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Search of human proteins with 38202224
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38202224 discs large-associated protein 2 [Homo sapiens]
(975 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38202224 discs large-associated protein 2 [Homo sapiens] 1989 0.0
gi|19923274 discs large homolog-associated protein 1 isoform alp... 924 0.0
gi|122937233 discs, large (Drosophila) homolog-associated protei... 811 0.0
gi|34335253 disks large-associated protein 4 isoform a [Homo sap... 677 0.0
gi|51339031 discs large homolog-associated protein 1 isoform bet... 649 0.0
gi|34335251 disks large-associated protein 4 isoform b [Homo sap... 393 e-109
gi|109891938 disks large-associated protein 4 isoform c [Homo sa... 313 4e-85
gi|226371669 discs large homolog 7 isoform b [Homo sapiens] 80 1e-14
gi|226371667 discs large homolog 7 isoform a [Homo sapiens] 80 1e-14
gi|83367077 mucin 16 [Homo sapiens] 40 0.008
gi|239758038 PREDICTED: mucin 3A, cell surface associated, parti... 38 0.040
gi|24762236 PRP38 pre-mRNA processing factor 38 (yeast) domain c... 38 0.040
gi|40805104 topoisomerase I binding, arginine/serine-rich [Homo ... 37 0.090
gi|7705555 iroquois homeobox 4 [Homo sapiens] 36 0.20
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 36 0.20
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 35 0.26
gi|109255230 centrosomal protein 170kDa isoform beta [Homo sapiens] 35 0.26
gi|109255228 centrosomal protein 170kDa isoform alpha [Homo sapi... 35 0.26
gi|109255232 centrosomal protein 170kDa isoform gamma [Homo sapi... 35 0.26
gi|115648142 centrosomal protein 164kDa [Homo sapiens] 35 0.34
gi|58530876 melanoma antigen family C, 1 [Homo sapiens] 35 0.34
gi|54607124 RNA binding motif protein 15B [Homo sapiens] 35 0.45
gi|187828892 calcium channel, alpha 1A subunit isoform 4 [Homo s... 34 0.58
gi|187828880 calcium channel, alpha 1A subunit isoform 3 [Homo s... 34 0.58
gi|148612840 RUN and TBC1 domain containing 2 isoform 3 [Homo sa... 34 0.58
gi|90577167 RUN and TBC1 domain containing 2 isoform 1 [Homo sap... 34 0.58
gi|18641364 protein tyrosine phosphatase, receptor type, C isofo... 34 0.76
gi|22209009 protein kinase CHK2 isoform b [Homo sapiens] 34 0.76
gi|6005850 protein kinase CHK2 isoform a [Homo sapiens] 34 0.76
gi|167736355 mucin 4 isoform a [Homo sapiens] 34 0.76
>gi|38202224 discs large-associated protein 2 [Homo sapiens]
Length = 975
Score = 1989 bits (5152), Expect = 0.0
Identities = 975/975 (100%), Positives = 975/975 (100%)
Query: 1 MKGLSGSRTQPPLCSGHTCGLAPPEDCEHLHHGPDARPPYLLSPADSCPGGRHRCSPRSS 60
MKGLSGSRTQPPLCSGHTCGLAPPEDCEHLHHGPDARPPYLLSPADSCPGGRHRCSPRSS
Sbjct: 1 MKGLSGSRTQPPLCSGHTCGLAPPEDCEHLHHGPDARPPYLLSPADSCPGGRHRCSPRSS 60
Query: 61 VHSECVMMPVVLGDHVSSSTFPRMHYSSHYDTRDDCAVAHAGAKINRIPANLLDQFEKQL 120
VHSECVMMPVVLGDHVSSSTFPRMHYSSHYDTRDDCAVAHAGAKINRIPANLLDQFEKQL
Sbjct: 61 VHSECVMMPVVLGDHVSSSTFPRMHYSSHYDTRDDCAVAHAGAKINRIPANLLDQFEKQL 120
Query: 121 PLHRDGFHTLQYQRTSAAAEQRSESPGRIRHLVHSVQKLFTKSHSLEGSSKSNANGTKAD 180
PLHRDGFHTLQYQRTSAAAEQRSESPGRIRHLVHSVQKLFTKSHSLEGSSKSNANGTKAD
Sbjct: 121 PLHRDGFHTLQYQRTSAAAEQRSESPGRIRHLVHSVQKLFTKSHSLEGSSKSNANGTKAD 180
Query: 181 GRADDHHHAHHAKHSKRSKSKERKPEGKPRPGMSSWWSSDDNLDSDSTYRTPSVLNRHHL 240
GRADDHHHAHHAKHSKRSKSKERKPEGKPRPGMSSWWSSDDNLDSDSTYRTPSVLNRHHL
Sbjct: 181 GRADDHHHAHHAKHSKRSKSKERKPEGKPRPGMSSWWSSDDNLDSDSTYRTPSVLNRHHL 240
Query: 241 GPVAHCYPDALQSPFGDLSLKTSKSNNDVKCSACEGLALTPDAKYLKRSSWSTLTVSQAK 300
GPVAHCYPDALQSPFGDLSLKTSKSNNDVKCSACEGLALTPDAKYLKRSSWSTLTVSQAK
Sbjct: 241 GPVAHCYPDALQSPFGDLSLKTSKSNNDVKCSACEGLALTPDAKYLKRSSWSTLTVSQAK 300
Query: 301 EAYRKSSLNLDKPLLHQDAKPALRPCHYLQVPQDEWGGYPTGGKDEEIPCRRMRSGSYIK 360
EAYRKSSLNLDKPLLHQDAKPALRPCHYLQVPQDEWGGYPTGGKDEEIPCRRMRSGSYIK
Sbjct: 301 EAYRKSSLNLDKPLLHQDAKPALRPCHYLQVPQDEWGGYPTGGKDEEIPCRRMRSGSYIK 360
Query: 361 AMGDEESGESDSSPKTSPKSAILPEPLLKSIGQRPLGEHQTQTYLQAASDVPVGHSLDPA 420
AMGDEESGESDSSPKTSPKSAILPEPLLKSIGQRPLGEHQTQTYLQAASDVPVGHSLDPA
Sbjct: 361 AMGDEESGESDSSPKTSPKSAILPEPLLKSIGQRPLGEHQTQTYLQAASDVPVGHSLDPA 420
Query: 421 ANYNSPKFRSRNQSYMRAVSTLSQASCVSQVSEAEINGQFESVCESVFSEVESQAMDALD 480
ANYNSPKFRSRNQSYMRAVSTLSQASCVSQVSEAEINGQFESVCESVFSEVESQAMDALD
Sbjct: 421 ANYNSPKFRSRNQSYMRAVSTLSQASCVSQVSEAEINGQFESVCESVFSEVESQAMDALD 480
Query: 481 LPGCFRTRSHSYLRAIQAGYSQDDECIPMMTPSDITSTIRSTAAVSYTNYKKTPPPVPPR 540
LPGCFRTRSHSYLRAIQAGYSQDDECIPMMTPSDITSTIRSTAAVSYTNYKKTPPPVPPR
Sbjct: 481 LPGCFRTRSHSYLRAIQAGYSQDDECIPMMTPSDITSTIRSTAAVSYTNYKKTPPPVPPR 540
Query: 541 TTSKPLISVTAQSSTESTQDAYQDSRAQRMSPWPQDSRGLYNSTDSLDSNKAMNLALETA 600
TTSKPLISVTAQSSTESTQDAYQDSRAQRMSPWPQDSRGLYNSTDSLDSNKAMNLALETA
Sbjct: 541 TTSKPLISVTAQSSTESTQDAYQDSRAQRMSPWPQDSRGLYNSTDSLDSNKAMNLALETA 600
Query: 601 AAQRHLPESQSSSVRTSDKAILVSKAEELLKSRCSSIGIQDSEFPEHQPYPRSDVETATD 660
AAQRHLPESQSSSVRTSDKAILVSKAEELLKSRCSSIGIQDSEFPEHQPYPRSDVETATD
Sbjct: 601 AAQRHLPESQSSSVRTSDKAILVSKAEELLKSRCSSIGIQDSEFPEHQPYPRSDVETATD 660
Query: 661 SDTESRGLREYHSVGVQVEDEKRHGRFKRSNSVTAAVQADLELEGFPGHITTEDKGLQFG 720
SDTESRGLREYHSVGVQVEDEKRHGRFKRSNSVTAAVQADLELEGFPGHITTEDKGLQFG
Sbjct: 661 SDTESRGLREYHSVGVQVEDEKRHGRFKRSNSVTAAVQADLELEGFPGHITTEDKGLQFG 720
Query: 721 SSFQRHSEPSTPTQYSAVRTVRTQGLFSYREDYRTQVDTSTLPPPDPWLEPAIDTVETGR 780
SSFQRHSEPSTPTQYSAVRTVRTQGLFSYREDYRTQVDTSTLPPPDPWLEPAIDTVETGR
Sbjct: 721 SSFQRHSEPSTPTQYSAVRTVRTQGLFSYREDYRTQVDTSTLPPPDPWLEPAIDTVETGR 780
Query: 781 MSPCRRDGSWFLKLLHAETKRMEGWCKEMEREAEENDLSEEILGKIRSAVGSAQLLMSQK 840
MSPCRRDGSWFLKLLHAETKRMEGWCKEMEREAEENDLSEEILGKIRSAVGSAQLLMSQK
Sbjct: 781 MSPCRRDGSWFLKLLHAETKRMEGWCKEMEREAEENDLSEEILGKIRSAVGSAQLLMSQK 840
Query: 841 FQQFYWLCQQNMDPSAMPRPTSQDLAGYWDMLQLSIEDVSMKFDELQRLRLNDWKMMESP 900
FQQFYWLCQQNMDPSAMPRPTSQDLAGYWDMLQLSIEDVSMKFDELQRLRLNDWKMMESP
Sbjct: 841 FQQFYWLCQQNMDPSAMPRPTSQDLAGYWDMLQLSIEDVSMKFDELQRLRLNDWKMMESP 900
Query: 901 ERKEERKVPPPIPKKPPKGKFPITREKSLDLPDRQRQEARRRLMAAKRAASFRQNSASER 960
ERKEERKVPPPIPKKPPKGKFPITREKSLDLPDRQRQEARRRLMAAKRAASFRQNSASER
Sbjct: 901 ERKEERKVPPPIPKKPPKGKFPITREKSLDLPDRQRQEARRRLMAAKRAASFRQNSASER 960
Query: 961 ADSIEIYIPEAQTRL 975
ADSIEIYIPEAQTRL
Sbjct: 961 ADSIEIYIPEAQTRL 975
>gi|19923274 discs large homolog-associated protein 1 isoform alpha
[Homo sapiens]
Length = 977
Score = 924 bits (2389), Expect = 0.0
Identities = 541/1020 (53%), Positives = 673/1020 (65%), Gaps = 88/1020 (8%)
Query: 1 MKGLSGSRTQPPLCSGHTCGLAPPEDCEHLHHGPDARPPYLLSPADSCPGGRHRCSPRSS 60
MKGLSGSR+ G TC A C+ L H D R PYLLSP + P + R+S
Sbjct: 1 MKGLSGSRSHH---HGVTCDSA----CDSLSHHSD-RKPYLLSPVEHHPADHPYYTQRNS 52
Query: 61 VHSECVMMPVVLGDHVSSSTFPRMHYSSHYDTRDDCAVAHA--GAKINRIPANLLDQFEK 118
+ECV D ++SSTFPR HY+S + +D+CA+ K NRIPANLLDQFE+
Sbjct: 53 FQAECVGP---FSDPLASSTFPRRHYTSQQELKDECALVPRTLATKANRIPANLLDQFER 109
Query: 119 QLPLHRDGFHTLQYQRTSAAAEQRSESPGRIRHLVHSVQKLFTKSHSLEGSSKSNANGTK 178
QLPL RDG+HTLQY+RT A E RS+SPGRIRHLVHSVQKLFTKSHSLEG SK + NG K
Sbjct: 110 QLPLSRDGYHTLQYKRT--AVEHRSDSPGRIRHLVHSVQKLFTKSHSLEGPSKGSVNGGK 167
Query: 179 ADGRADDHHHAHHAKHSKRSKSKERKPEGKPRPGMS-SWWSSDDNLDSDST-YRTPSVLN 236
A A A++ KRSKSKER+ E K RP S WWSSDDNLD D Y PS +
Sbjct: 168 ASP-----DEAQAARYGKRSKSKERRAEPKARPSTSPGWWSSDDNLDGDMCIYHAPSGVM 222
Query: 237 RHHLGP--VAHCYPDALQSPFGDLSLKTSKSNNDVKCSACEGLALTPDAKYLKRSSWS-T 293
P A Y + + ++K S+SNNDVKCS C L ++ D LK+S+WS T
Sbjct: 223 TMGRCPDRSASQYFLEAYNTISEQAVKASRSNNDVKCSTCANLPVSLDTPLLKKSAWSST 282
Query: 294 LTVSQAKEAYRKSSLNLDKPLLHQDAKPALRPCHYLQVPQDEWGGYPTGGKDEEIPCRRM 353
LTVS+A+E Y+K+S+N+D+ ++ ++ R C YLQVPQDEW GY GKD+EIPCRRM
Sbjct: 283 LTVSRAREVYQKASVNMDQAMVKSESCQQERSCQYLQVPQDEWTGYTPRGKDDEIPCRRM 342
Query: 354 RSGSYIKAMGDEESGESDSSPKTSPKSAILPEPLLK--------------SIGQRPLGEH 399
RSGSYIKAMGDE+SG+SD+SPK SPK A E LK S P +
Sbjct: 343 RSGSYIKAMGDEDSGDSDTSPKPSPKVAARRESYLKATQPSLTELTTLKISNEHSPKLQI 402
Query: 400 QTQTYLQAASDVPVGHSLD---PAANYNSPKFRSRNQSYMRAVSTLSQASCVSQVSEAEI 456
++ +YL+A S+V + SLD PA SPKFRSRN+SYMRA+ST +SQVSE E+
Sbjct: 403 RSHSYLRAVSEVSINRSLDSLDPAGLLTSPKFRSRNESYMRAMST------ISQVSEMEV 456
Query: 457 NGQFESVCESVFSEVESQAMDALDLP--GCFRTRSHSYLRAIQAGYSQDDECIPMMT--P 512
NGQFESVCESVFSE+ESQA++ALDLP GCFR RSHSY+RAI+ G SQDDEC+ + + P
Sbjct: 457 NGQFESVCESVFSELESQAVEALDLPMPGCFRMRSHSYVRAIEKGCSQDDECVSLRSSSP 516
Query: 513 SDITSTIR----STAAVSYTNYKKTPPPVPPRTTSKPLISVTAQSSTESTQDAYQDSRAQ 568
T+T+R ST + T YKKTPPPVPPRTT+KP IS+TAQSSTES QDAY D + Q
Sbjct: 517 PRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMDGQGQ 576
Query: 569 RMSPWPQDSRGLYNSTDSLDSNKAMNLALETAAAQRHLPESQ-----SSSVRTSDKAILV 623
R Q GL NST+SLDS KA+ A+E A AQ H P SQ +++V T+ V
Sbjct: 577 RGDIISQS--GLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTTIATV 634
Query: 624 S----KAEELLKSRCSSIGIQ--DSEFPEHQPYPRSDVETATDSDTESRGLREYHSVGVQ 677
+ K + K+RC SIGIQ D+E P D E++ ++ SVGVQ
Sbjct: 635 TTEDRKKDHFKKNRCLSIGIQVDDAEEP--------------DKTGENKAPSKFQSVGVQ 680
Query: 678 VEDEKRHGRFKRSNSVTAAVQADLEL-EGFPGHITTEDKGLQFGSSFQRHSEPSTPTQYS 736
VE+EK RF RSNSVT AVQADL+ + + + + G ++ S ++ + S
Sbjct: 681 VEEEKCFRRFTRSNSVTTAVQADLDFHDNLENSLESIEDNSCPGPMARQFSRDASTSTVS 740
Query: 737 AVRTVRTQGLFSYREDYRTQVDTSTLPPPDPWLEPAI-DTVETGRMSPCRRDGSWFLKLL 795
+ + +D+ T D S LPPPDPW++ D +E + S C RDG WFLKLL
Sbjct: 741 IQGSGNHYHACAADDDFDTDFDPSILPPPDPWIDSITEDPLEAVQRSVCHRDGHWFLKLL 800
Query: 796 HAETKRMEGWCKEMEREAEENDLSEEILGKIRSAVGSAQLLMSQKFQQFYWLCQQNMDPS 855
AE RMEGWC++MERE EN+L E+ILGKIR+AVGSAQLLM+QKF QF LC++N++P+
Sbjct: 801 QAERDRMEGWCQQMEREERENNLPEDILGKIRTAVGSAQLLMAQKFYQFRELCEENLNPN 860
Query: 856 AMPRPTSQDLAGYWDMLQLSIEDVSMKFDELQRLRLNDWKMMESPERKEERKVPPPIPKK 915
A PRPTSQDLAG+WDMLQLSIE++SMKFDEL +L+ N+WK M+ P K+ER+ PPP+PKK
Sbjct: 861 AHPRPTSQDLAGFWDMLQLSIENISMKFDELHQLKANNWKQMD-PLDKKERRAPPPVPKK 919
Query: 916 PPKGKFPITREKSLDLPDRQRQEARRRLMAAKRAASFRQNSASERADSIEIYIPEAQTRL 975
P KG P+ RE+SL+ QRQEAR+RLMAAKRAAS RQNSA+E A+SIEIYIPEAQTRL
Sbjct: 920 PAKGPAPLIRERSLE--SSQRQEARKRLMAAKRAASVRQNSATESAESIEIYIPEAQTRL 977
>gi|122937233 discs, large (Drosophila) homolog-associated protein 3
[Homo sapiens]
Length = 979
Score = 811 bits (2096), Expect = 0.0
Identities = 490/1029 (47%), Positives = 618/1029 (60%), Gaps = 147/1029 (14%)
Query: 26 DCEHLHHGPDARPPYLLSPADSCPGGRHRCSPRSSVHSECVMMPVVLGDHVS-------- 77
D +H+ GP AR PYLL ++ C+PR+ + P+ L + S
Sbjct: 19 DQQHMDVGPAARAPYLLGSREAFSTEPRFCAPRAGLGHISPEGPLSLSEGPSVGPEGGPA 78
Query: 78 -------SSTFPRMHYSSH-YDTRDDCAVAHAGAKINRIPANLLDQFEKQLPLHRDGFHT 129
SSTFPRM+ +DT +DC G R+P LLDQFEKQLP+ +DGFHT
Sbjct: 79 GAGVGGGSSTFPRMYPGQGPFDTCEDCVGHPQGKGAPRLPPTLLDQFEKQLPVQQDGFHT 138
Query: 130 LQYQR------------TSAAAEQRSESPGRIRHLVHSVQKLFTKSHSLEGSSKSNANGT 177
L YQR T A E RSESP RIRHLVHSVQKLF KSHSLE K + NG
Sbjct: 139 LPYQRGPAGAGPGPAPGTGTAPEPRSESPSRIRHLVHSVQKLFAKSHSLEAPGKRDYNGP 198
Query: 178 KADGRADD-----------------------HHHAHHAKHSKRSKSKERKPEGKPRPGMS 214
KA+GR HHH H ++H KRSKSK+RK +G+ + +
Sbjct: 199 KAEGRGGSGGDSYPGPGSGGPHTSHHHHHHHHHHHHQSRHGKRSKSKDRKGDGRHQAKST 258
Query: 215 SWWSSDDNLDSDSTYRTPSVLNRHHLGPVAHCYPDALQSPFGDLSLKTSKSNNDVKCSAC 274
WWSSDDNLDSDS + GP PD + DLS K ++ +C AC
Sbjct: 259 GWWSSDDNLDSDSGFLAGGRPPGEPGGPFCLEGPDG---SYRDLSFKGRSGGSEGRCLAC 315
Query: 275 EGLALTPDAKYLKRSSWSTLTVSQAKEAYRKSSLNLDKPLLHQDAKPALRPCHYLQVPQD 334
G++++ D + +KRS+W T+ VSQ ++ Y + K LL + K R HYLQVPQD
Sbjct: 316 TGMSMSLDGQSVKRSAWHTMMVSQGRDGYPGAGPG--KGLLGPETKAKARTYHYLQVPQD 373
Query: 335 EWGGYPTGGKDEEIPCRRMRSGSYIKAMGDEESGESDSSPKTSPKSAILPEPLLKSIGQR 394
+WGGYPTGGKD EIPCRRMRSGSYIKAMGDEESG+SD SPKTSPK+ R
Sbjct: 374 DWGGYPTGGKDGEIPCRRMRSGSYIKAMGDEESGDSDGSPKTSPKAVA-----------R 422
Query: 395 PLGEHQTQTYLQAASDVPVGHSLDPAANYNSPKFRSRNQSYMRAVSTLSQASCVSQVSEA 454
++ + QA + V + P RS Y R+++T Q+S+
Sbjct: 423 RFTTRRSSSVDQARINCCVPPRIHP---------RSSIPGYSRSLTT-------GQLSD- 465
Query: 455 EINGQFESVCESVFSEVESQAMDALDLPGCFRTRSHSYLRAIQAGYSQDDECIPMM-TPS 513
E+N Q E+VC SVF E+ESQA+DALDLPGCFR RSHSYLRAIQAG SQDD+C+P++ TP+
Sbjct: 466 ELNQQLEAVCGSVFGELESQAVDALDLPGCFRMRSHSYLRAIQAGCSQDDDCLPLLATPA 525
Query: 514 DITSTIRSTAAVSYTNYKKTPPPVPPRTTSKPLISVTAQSSTESTQDAYQ--DSRAQRMS 571
++ S+ N++K PPP+PP + + P IS+TAQSST+S +++ + A+R S
Sbjct: 526 AVSGRPGSSF-----NFRKAPPPIPPGSQAPPRISITAQSSTDSAHESFTAAEGPARRCS 580
Query: 572 PWPQDSRGLYNSTDSLDSNKAMNLALETAAAQ-RHLPESQSSSVRTSDKAILVSKAEELL 630
S D LD LE A R P+ + ++T +
Sbjct: 581 -----------SADGLDGPAMGARTLELAPVPPRASPKPPTLIIKTIPGREELRSLARQR 629
Query: 631 KSRCSSIGIQDSEFPEHQPYPRSDVETATDSDTESRGLREYHSVGVQVEDEKRHGRFKRS 690
K R SIG+Q VET +DSDTE+R RE+HS+GVQVE++KR RFKRS
Sbjct: 630 KWR-PSIGVQ--------------VETISDSDTENRSRREFHSIGVQVEEDKRRARFKRS 674
Query: 691 NSVTAAVQADLELEGFPGHIT--TEDKGLQFGSSFQRHSE-----PSTPTQYSAVRTVRT 743
NSVTA VQADLELEG G T TEDK LQFG SFQRH+ P PT YS RTV T
Sbjct: 675 NSVTAGVQADLELEGLAGLATVATEDKALQFGRSFQRHASEPQPGPRAPT-YSVFRTVHT 733
Query: 744 QGLFSYREDYRTQ-----VDTSTLPPPDP-----------WLEPAIDTV-ETGRMSPCRR 786
QG ++YRE Y D S P P P W+E ++ ++GR SPC R
Sbjct: 734 QGQWAYREGYPLPYEPPATDGSPGPAPAPTPGPGAGRRDSWIERGSRSLPDSGRASPCPR 793
Query: 787 DGSWFLKLLHAETKRMEGWCKEMEREAEENDLSEEILGKIRSAVGSAQLLMSQKFQQFYW 846
DG WF+K+L AE +++E WC++MEREAE+ +L EEIL KIRSAVGS QLL+SQK QQF+
Sbjct: 794 DGEWFIKMLRAEVEKLEHWCQQMEREAEDYELPEEILEKIRSAVGSTQLLLSQKVQQFFR 853
Query: 847 LCQQNMDPSAMPRPTSQDLAGYWDMLQLSIEDVSMKFDELQRLRLNDWKMMESPERKEER 906
LCQQ+MDP+A P PT QDLAG+WD+LQLSIEDV++KF ELQ+L+ N WK++E KEE+
Sbjct: 854 LCQQSMDPTAFPVPTFQDLAGFWDLLQLSIEDVTLKFLELQQLKANSWKLLEP---KEEK 910
Query: 907 KVPPPIPKKPPKGKFPITREKSLDLPDRQRQEARRRLMAAKRAASFRQNSASERADSIEI 966
KVPPPIPKKP +G+ +E+SLD DRQRQEAR+RL+AAKRAASFR +SA+E ADSIEI
Sbjct: 911 KVPPPIPKKPLRGRGVPVKERSLDSVDRQRQEARKRLLAAKRAASFRHSSATESADSIEI 970
Query: 967 YIPEAQTRL 975
YIPEAQTRL
Sbjct: 971 YIPEAQTRL 979
>gi|34335253 disks large-associated protein 4 isoform a [Homo
sapiens]
Length = 989
Score = 677 bits (1747), Expect = 0.0
Identities = 452/1053 (42%), Positives = 591/1053 (56%), Gaps = 142/1053 (13%)
Query: 1 MKGLSGSRTQPPLCSGHTCGLAPPEDCEHLHHGPDARPPYLLSPADSCPGGRHRCSPRSS 60
MKGL SR + S L PP E L G D R PYLLSP ++ R P +
Sbjct: 1 MKGLGDSRPRHLSDS-----LDPPH--EPLFAGTD-RNPYLLSPTEAF--AREARFPGQN 50
Query: 61 VHSECVMMPVVLGDHVSSSTFPRMHYSSHYDTRDDCAV-AHAGA-KINRIPANLLDQFEK 118
+ P+ SSTFPR+HY+SH++ ++ +HA A KINR+PANLLDQFEK
Sbjct: 51 TLPGDGLFPLNNQLPPPSSTFPRIHYNSHFEVPEESPFPSHAQATKINRLPANLLDQFEK 110
Query: 119 QLPLHRDGFHTLQYQRTSAAAEQRSESPGRIRHLVHSVQKLF-TKSHSLEGSS-KSNANG 176
QLP+HRDGF TLQ+ R A A R ESPGRIRHLVHSVQ+LF TK+ SLEG++ K NG
Sbjct: 111 QLPIHRDGFSTLQFPRGEAKA--RGESPGRIRHLVHSVQRLFFTKAPSLEGTAGKVGGNG 168
Query: 177 TKADGRADDHHHAHHAKHSKRSKSKERKPEGKP----RPGMSSWWSSDDNLDSDS-TYRT 231
+K G D +R+KSKER G+P R +S WWSSDDNLD ++ +R+
Sbjct: 169 SKKGGMEDGK--------GRRAKSKERAKAGEPKRRSRSNISGWWSSDDNLDGEAGAFRS 220
Query: 232 PS------VLNRHHLGPVAHCYPDALQSPFGDLSLKTSKSNND---------VKCSACEG 276
L R + A + G + LKT+K+N + C
Sbjct: 221 SGPASGLMTLGRQAERSQPRYFMHAYNTISGHM-LKTTKNNTTELTAPPPPPAPPATCPS 279
Query: 277 LALTPDAKYLKRSSWSTLTVSQAKEAYRKSSLNLDKPLLHQDAKPALRPCHYLQVPQD-- 334
L + D Y+KR SWSTLT+S A E +K+S LDK LL + HYLQVP
Sbjct: 280 LGVGTDTNYVKRGSWSTLTLSHAHEVCQKTSATLDKSLLKSKSCHQGLAYHYLQVPGGGG 339
Query: 335 EWGGYPTGGKDEE------IPCRRMRSGSYIKAMGDEESGESDSSPKTSPKSAILPEPLL 388
EW ++ + IPCRRMRSGSYIKAMGDE+S ES SPK SPK+A + L
Sbjct: 340 EWSTTLLSPRETDAAAEGPIPCRRMRSGSYIKAMGDEDSDESGGSPKPSPKTAARRQSYL 399
Query: 389 KSIGQRPLGEHQTQTYLQAASDVPVGHSLDPAANYNSPKFRSRNQSYMRAVSTLSQASCV 448
++ Q+ LGE Q+ + + D LD K S + Y +L+ +SC+
Sbjct: 400 RAT-QQSLGE---QSNPRRSLD-----RLDSVDMLLPSKCPSWEEDYTPVSDSLNDSSCI 450
Query: 449 SQ-----------------VSEAEINGQFESVCESVFSEVESQAMDALDLP--GCFRTRS 489
SQ V EAE++ Q+E+ CES SE ES A + LDLP FR+RS
Sbjct: 451 SQIFGQASLIPQLFGHEQQVREAELSDQYEAACESACSEAESTAAETLDLPLPSYFRSRS 510
Query: 490 HSYLRAIQAGYSQDDECIPM--MTPSDITSTIRSTAAVSYTN----YKKTPPPVPPRTTS 543
HSYLRAIQAG SQ+++ + + ++P T ++ ++ + ++ YKKTPPPVPPRTTS
Sbjct: 511 HSYLRAIQAGCSQEEDSVSLQSLSPPPSTGSLSNSRTLPSSSCLVAYKKTPPPVPPRTTS 570
Query: 544 KPLISVTAQSSTESTQDAYQDSRAQRMSPWPQDSRGLYNSTDSLDSNKAMNLALETAAAQ 603
KP ISVT QSSTES QD Y DS+ + Q GL NS+DSLDS+
Sbjct: 571 KPFISVTVQSSTESAQDTYLDSQDHKSEVTSQS--GLSNSSDSLDSSTRP---------- 618
Query: 604 RHLPESQSSSVRTSDKAILVSKAEELLKSRCSSIGIQDSEFPEHQPYPRSDVETATDSDT 663
P V + +A LKS ++ T+++S
Sbjct: 619 ---PSVTRGGVAPAPEAPEPPPKHAALKSEQGTL-------------------TSSESHP 656
Query: 664 ESRGLREYHSVGVQVEDEKRHGRFKRSNSVTAA-VQADLELEGFPGHIT---------TE 713
E+ R+ S+G+Q + N A V A P H T+
Sbjct: 657 EAAPKRKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAPSSESSVPSHSMSSRRDTDSDTQ 716
Query: 714 DKGLQFGSSFQRHSEPSTPTQYS---------AVRTVRTQGLFSYREDYRTQVDTSTLPP 764
D S +R TP S A + + + SY ++ ++ S+LPP
Sbjct: 717 DANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPP 776
Query: 765 PDPWLEPAIDT-VETGRMSPCRRDGSWFLKLLHAETKRMEGWCKEMEREAEENDLSEEIL 823
PDPWLE + + E + CRRDG WFLKLL AET+R+EGWC +M++E +EN+LSEE+L
Sbjct: 777 PDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVL 836
Query: 824 GKIRSAVGSAQLLMSQKFQQFYWLCQQNMDPSAMPRPTSQDLAGYWDMLQLSIEDVSMKF 883
GK+ SAVGSAQLLMSQKFQQF LC+QN++P A PRPT+QDLAG+WD+LQLSIED+SMKF
Sbjct: 837 GKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKF 896
Query: 884 DELQRLRLNDWKMMESPE-RKEERKVPPPIPKKPPKGKFPITREKSLDLPDRQRQEARRR 942
DEL L+ N W+++E+PE RKEE+K PPP+PKKP K K ++R+K+ D D+QRQEAR+R
Sbjct: 897 DELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKR 956
Query: 943 LMAAKRAASFRQNSASERADSIEIYIPEAQTRL 975
L+AAKRAAS RQNSA+E ADSIEIY+PEAQTRL
Sbjct: 957 LLAAKRAASVRQNSATESADSIEIYVPEAQTRL 989
>gi|51339031 discs large homolog-associated protein 1 isoform beta
[Homo sapiens]
Length = 675
Score = 649 bits (1673), Expect = 0.0
Identities = 372/684 (54%), Positives = 463/684 (67%), Gaps = 63/684 (9%)
Query: 330 QVPQDEWGGYPTGGKDEEIPCRRMRSGSYIKAMGDEESGESDSSPKTSPKSAILPEPLLK 389
+VPQDEW GY GKD+EIPCRRMRSGSYIKAMGDE+SG+SD+SPK SPK A E LK
Sbjct: 17 KVPQDEWTGYTPRGKDDEIPCRRMRSGSYIKAMGDEDSGDSDTSPKPSPKVAARRESYLK 76
Query: 390 --------------SIGQRPLGEHQTQTYLQAASDVPVGHSLD---PAANYNSPKFRSRN 432
S P + ++ +YL+A S+V + SLD PA SPKFRSRN
Sbjct: 77 ATQPSLTELTTLKISNEHSPKLQIRSHSYLRAVSEVSINRSLDSLDPAGLLTSPKFRSRN 136
Query: 433 QSYMRAVSTLSQASCVSQVSEAEINGQFESVCESVFSEVESQAMDALDLP--GCFRTRSH 490
+SYMRA+ST +SQVSE E+NGQFESVCESVFSE+ESQA++ALDLP GCFR RSH
Sbjct: 137 ESYMRAMST------ISQVSEMEVNGQFESVCESVFSELESQAVEALDLPMPGCFRMRSH 190
Query: 491 SYLRAIQAGYSQDDECIPMMT--PSDITSTIR----STAAVSYTNYKKTPPPVPPRTTSK 544
SY+RAI+ G SQDDEC+ + + P T+T+R ST + T YKKTPPPVPPRTT+K
Sbjct: 191 SYVRAIEKGCSQDDECVSLRSSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTK 250
Query: 545 PLISVTAQSSTESTQDAYQDSRAQRMSPWPQDSRGLYNSTDSLDSNKAMNLALETAAAQR 604
P IS+TAQSSTES QDAY D + QR Q GL NST+SLDS KA+ A+E A AQ
Sbjct: 251 PFISITAQSSTESAQDAYMDGQGQRGDIISQS--GLSNSTESLDSMKALTAAIEAANAQI 308
Query: 605 HLPESQ-----SSSVRTSDKAILVS----KAEELLKSRCSSIGIQ--DSEFPEHQPYPRS 653
H P SQ +++V T+ V+ K + K+RC SIGIQ D+E P
Sbjct: 309 HGPASQHMGNNTATVTTTTTIATVTTEDRKKDHFKKNRCLSIGIQVDDAEEP-------- 360
Query: 654 DVETATDSDTESRGLREYHSVGVQVEDEKRHGRFKRSNSVTAAVQADLEL-EGFPGHITT 712
D E++ ++ SVGVQVE+EK RF RSNSVT AVQADL+ + + +
Sbjct: 361 ------DKTGENKAPSKFQSVGVQVEEEKCFRRFTRSNSVTTAVQADLDFHDNLENSLES 414
Query: 713 EDKGLQFGSSFQRHSEPSTPTQYSAVRTVRTQGLFSYREDYRTQVDTSTLPPPDPWLEPA 772
+ G ++ S ++ + S + + +D+ T D S LPPPDPW++
Sbjct: 415 IEDNSCPGPMARQFSRDASTSTVSIQGSGNHYHACAADDDFDTDFDPSILPPPDPWIDSI 474
Query: 773 I-DTVETGRMSPCRRDGSWFLKLLHAETKRMEGWCKEMEREAEENDLSEEILGKIRSAVG 831
D +E + S C RDG WFLKLL AE RMEGWC++MERE EN+L E+ILGKIR+AVG
Sbjct: 475 TEDPLEAVQRSVCHRDGHWFLKLLQAERDRMEGWCQQMEREERENNLPEDILGKIRTAVG 534
Query: 832 SAQLLMSQKFQQFYWLCQQNMDPSAMPRPTSQDLAGYWDMLQLSIEDVSMKFDELQRLRL 891
SAQLLM+QKF QF LC++N++P+A PRPTSQDLAG+WDMLQLSIE++SMKFDEL +L+
Sbjct: 535 SAQLLMAQKFYQFRELCEENLNPNAHPRPTSQDLAGFWDMLQLSIENISMKFDELHQLKA 594
Query: 892 NDWKMMESPERKEERKVPPPIPKKPPKGKFPITREKSLDLPDRQRQEARRRLMAAKRAAS 951
N+WK M+ P K+ER+ PPP+PKKP KG P+ RE+SL+ QRQEAR+RLMAAKRAAS
Sbjct: 595 NNWKQMD-PLDKKERRAPPPVPKKPAKGPAPLIRERSLE--SSQRQEARKRLMAAKRAAS 651
Query: 952 FRQNSASERADSIEIYIPEAQTRL 975
RQNSA+E A+SIEIYIPEAQTRL
Sbjct: 652 VRQNSATESAESIEIYIPEAQTRL 675
>gi|34335251 disks large-associated protein 4 isoform b [Homo
sapiens]
Length = 453
Score = 393 bits (1010), Expect = e-109
Identities = 226/462 (48%), Positives = 295/462 (63%), Gaps = 42/462 (9%)
Query: 530 YKKTPPPVPPRTTSKPLISVTAQSSTESTQDAYQDSRAQRMSPWPQDSRGLYNSTDSLDS 589
YKKTPPPVPPRTTSKP ISVT QSSTES QD Y DS+ + Q GL NS+DSLDS
Sbjct: 18 YKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQS--GLSNSSDSLDS 75
Query: 590 NK---AMNLALETAAAQRHLPESQSSSVRTSDKAILVSKA--EELLKSRCSSIGIQDSEF 644
+ ++ A + P + +++++ + S++ E K + SSIGIQ
Sbjct: 76 STRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCI 135
Query: 645 PEHQPYPRSDVETATDSDTESRGLREYHSVGVQVEDEKRHGRFKRSNSVTAAVQADLELE 704
QP P+ + AT ++ S+GVQVED+ R S S +D
Sbjct: 136 ---QPVPKEEPSPAT----------KFQSIGVQVEDDWRSSVPSHSMSSRRDTDSD---- 178
Query: 705 GFPGHITTEDKGLQFGSSFQRHSEPSTPTQYS---------AVRTVRTQGLFSYREDYRT 755
T+D S +R TP S A + + + SY ++
Sbjct: 179 -------TQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDP 231
Query: 756 QVDTSTLPPPDPWLEPAIDT-VETGRMSPCRRDGSWFLKLLHAETKRMEGWCKEMEREAE 814
++ S+LPPPDPWLE + + E + CRRDG WFLKLL AET+R+EGWC +M++E +
Sbjct: 232 ALEASSLPPPDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETK 291
Query: 815 ENDLSEEILGKIRSAVGSAQLLMSQKFQQFYWLCQQNMDPSAMPRPTSQDLAGYWDMLQL 874
EN+LSEE+LGK+ SAVGSAQLLMSQKFQQF LC+QN++P A PRPT+QDLAG+WD+LQL
Sbjct: 292 ENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQL 351
Query: 875 SIEDVSMKFDELQRLRLNDWKMMESPE-RKEERKVPPPIPKKPPKGKFPITREKSLDLPD 933
SIED+SMKFDEL L+ N W+++E+PE RKEE+K PPP+PKKP K K ++R+K+ D D
Sbjct: 352 SIEDISMKFDELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASD 411
Query: 934 RQRQEARRRLMAAKRAASFRQNSASERADSIEIYIPEAQTRL 975
+QRQEAR+RL+AAKRAAS RQNSA+E ADSIEIY+PEAQTRL
Sbjct: 412 KQRQEARKRLLAAKRAASVRQNSATESADSIEIYVPEAQTRL 453
>gi|109891938 disks large-associated protein 4 isoform c [Homo
sapiens]
Length = 285
Score = 313 bits (803), Expect = 4e-85
Identities = 150/230 (65%), Positives = 190/230 (82%), Gaps = 2/230 (0%)
Query: 748 SYREDYRTQVDTSTLPPPDPWLEPAIDT-VETGRMSPCRRDGSWFLKLLHAETKRMEGWC 806
SY ++ ++ S+LPPPDPWLE + + E + CRRDG WFLKLL AET+R+EGWC
Sbjct: 56 SYGDNSDPALEASSLPPPDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWC 115
Query: 807 KEMEREAEENDLSEEILGKIRSAVGSAQLLMSQKFQQFYWLCQQNMDPSAMPRPTSQDLA 866
+M++E +EN+LSEE+LGK+ SAVGSAQLLMSQKFQQF LC+QN++P A PRPT+QDLA
Sbjct: 116 CQMDKETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLA 175
Query: 867 GYWDMLQLSIEDVSMKFDELQRLRLNDWKMMESPE-RKEERKVPPPIPKKPPKGKFPITR 925
G+WD+LQLSIED+SMKFDEL L+ N W+++E+PE RKEE+K PPP+PKKP K K ++R
Sbjct: 176 GFWDLLQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSR 235
Query: 926 EKSLDLPDRQRQEARRRLMAAKRAASFRQNSASERADSIEIYIPEAQTRL 975
+K+ D D+QRQEAR+RL+AAKRAAS RQNSA+E ADSIEIY+PEAQTRL
Sbjct: 236 DKASDASDKQRQEARKRLLAAKRAASVRQNSATESADSIEIYVPEAQTRL 285
>gi|226371669 discs large homolog 7 isoform b [Homo sapiens]
Length = 842
Score = 79.7 bits (195), Expect = 1e-14
Identities = 61/196 (31%), Positives = 95/196 (48%), Gaps = 12/196 (6%)
Query: 771 PAIDTVETGRMSPCRRDGSWFLKLLHAETKRMEGWCKEMEREAEENDLSEEILGKIRSAV 830
P+++ E GR++ +F +L +ET+++ C E +R+ E D+ ++ IR+AV
Sbjct: 414 PSLERNE-GRIAQPHHGVPYFRNILQSETEKLTSHCFEWDRKLEL-DIPDDAKDLIRTAV 471
Query: 831 GSAQLLMSQKFQQFYWLCQQNMDPSAMPRPTSQDLAGYWDMLQLSIEDVSMKFDELQRLR 890
G +LLM ++F+QF L + T DL G+WDM+ IEDV KF+ L +L
Sbjct: 472 GQTRLLMKERFKQFEGLVDDCEYKRGIKETTCTDLDGFWDMVSFQIEDVIHKFNNLIKLE 531
Query: 891 LNDWKMMESPERKEERKVPPPIPKKPPKGKFPITREKSLDLPDRQRQEARRRLMAAKRA- 949
+ W++ + + V KK G I + D D R AR RL A K A
Sbjct: 532 ESGWQVNNNMNHNMNKNV---FRKKVVSG---IASKPKQD--DAGRIAARNRLAAIKNAM 583
Query: 950 -ASFRQNSASERADSI 964
RQ +E A S+
Sbjct: 584 RERIRQEECAETAVSV 599
>gi|226371667 discs large homolog 7 isoform a [Homo sapiens]
Length = 846
Score = 79.7 bits (195), Expect = 1e-14
Identities = 61/196 (31%), Positives = 95/196 (48%), Gaps = 12/196 (6%)
Query: 771 PAIDTVETGRMSPCRRDGSWFLKLLHAETKRMEGWCKEMEREAEENDLSEEILGKIRSAV 830
P+++ E GR++ +F +L +ET+++ C E +R+ E D+ ++ IR+AV
Sbjct: 414 PSLERNE-GRIAQPHHGVPYFRNILQSETEKLTSHCFEWDRKLEL-DIPDDAKDLIRTAV 471
Query: 831 GSAQLLMSQKFQQFYWLCQQNMDPSAMPRPTSQDLAGYWDMLQLSIEDVSMKFDELQRLR 890
G +LLM ++F+QF L + T DL G+WDM+ IEDV KF+ L +L
Sbjct: 472 GQTRLLMKERFKQFEGLVDDCEYKRGIKETTCTDLDGFWDMVSFQIEDVIHKFNNLIKLE 531
Query: 891 LNDWKMMESPERKEERKVPPPIPKKPPKGKFPITREKSLDLPDRQRQEARRRLMAAKRA- 949
+ W++ + + V KK G I + D D R AR RL A K A
Sbjct: 532 ESGWQVNNNMNHNMNKNV---FRKKVVSG---IASKPKQD--DAGRIAARNRLAAIKNAM 583
Query: 950 -ASFRQNSASERADSI 964
RQ +E A S+
Sbjct: 584 RERIRQEECAETAVSV 599
>gi|83367077 mucin 16 [Homo sapiens]
Length = 14507
Score = 40.4 bits (93), Expect = 0.008
Identities = 63/292 (21%), Positives = 109/292 (37%), Gaps = 33/292 (11%)
Query: 357 SYIKAMGDEESGESDSSPKTSPKSAILPEPLLKSIGQRPLGEHQTQTYLQAASDVPVGHS 416
S+ KA +G + S KT P SA+L L + P + L S P G
Sbjct: 744 SHHKATSSITTGTPEISTKTKPSSAVLSSMTLSNAATSPERVRNATSPLTHPS--PSGEE 801
Query: 417 LDPAANYNSPKFRSRNQSYMRAVSTLS-----QASCVSQVSEAEINGQFESVCESVFSEV 471
+ S + + + TL+ S +S S + + F S S
Sbjct: 802 TAGSVLTLSTSAETTDSPNIHPTGTLTSESSESPSTLSLPSVSGVKTTFSSSTPSTHLFT 861
Query: 472 ESQAMDALDLPGCFRTR-SHSYLRAIQAGYSQDDECIPMM----------TPSDITSTIR 520
+ + P + S S +R A S P M + S + S +R
Sbjct: 862 SGEETEETSNPSVSQPETSVSRVRTTLASTSVPTPVFPTMDTWPTRSAQFSSSHLVSELR 921
Query: 521 STAAVSYTNYKKTPPPVPPRTTSKPLISVTAQSSTESTQDAYQDSRAQRMSPWPQDS--- 577
+T++ S TN + P T +S ++ +D + DS A + + WP+ S
Sbjct: 922 ATSSTSVTNSTGSALPKISHLTGTATMS-------QTNRDTFNDSAAPQSTTWPETSPRF 974
Query: 578 -RGLYNSTDSLDSNKAMNLALETAAAQRHLPESQS---SSVRTSDKAILVSK 625
GL ++T ++ S A +L+ ++ P + S +S+R IL ++
Sbjct: 975 KTGLPSATTTV-STSATSLSATVMVSKFTSPATSSMEATSIREPSTTILTTE 1025
>gi|239758038 PREDICTED: mucin 3A, cell surface associated, partial
[Homo sapiens]
Length = 909
Score = 38.1 bits (87), Expect = 0.040
Identities = 56/239 (23%), Positives = 84/239 (35%), Gaps = 28/239 (11%)
Query: 511 TPSDITSTIRSTAAVSYTNYKKTPPPVPPRTTSKPLISVTAQSSTESTQDAYQDSRAQRM 570
TPS TS+IR+T SY+ P TS I+ T ST S + +
Sbjct: 130 TPS-FTSSIRTTETTSYST---------PSFTSSNTITETTSHSTPSYITSITTTETPSS 179
Query: 571 SPWPQDSRGLYNSTDSLDSNKAMNLALETAAAQRHLPESQSSSVRTSDKAILVSKAEELL 630
S P S + + + S ++ T H S +SS+ T++
Sbjct: 180 ST-PSFSSSITTTETTSHSTPGFTSSITTTETTSHSTPSFTSSITTTE------TTSHDT 232
Query: 631 KSRCSSIGIQDSEFPEHQPYPRSDVETATDSDTESRGLREYHSVGVQVEDEKRHGRFKRS 690
S SS I SE P H S T + T S + S + + H +
Sbjct: 233 PSFTSS--ITTSETPSHS--TPSSTSLITTTKTTSHSTPSFTS-SITTTETTSHSAHSFT 287
Query: 691 NSVTAAVQADLELEGFPGHITTEDKGLQFGSSF------QRHSEPSTPTQYSAVRTVRT 743
+S+T F ITT + +SF + STP+ S++ T T
Sbjct: 288 SSITTTETTSHNTRSFTSSITTTETNSHSTTSFTSSITTTETTSHSTPSFSSSITTTET 346
>gi|24762236 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing A [Homo sapiens]
Length = 312
Score = 38.1 bits (87), Expect = 0.040
Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 5/72 (6%)
Query: 133 QRTSAAAEQRSESPGRIRHLVHSVQKLFTKSHSLEGSSKSNANGTKADGRADDHHHAHHA 192
+R S + ++RS SP R RH S ++ ++S S+S K+ G H H H+
Sbjct: 240 RRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRS-----KSPGHHRSHRHRSHS 294
Query: 193 KHSKRSKSKERK 204
K +RSK +K
Sbjct: 295 KSPERSKKSHKK 306
>gi|40805104 topoisomerase I binding, arginine/serine-rich [Homo
sapiens]
Length = 1045
Score = 37.0 bits (84), Expect = 0.090
Identities = 37/120 (30%), Positives = 57/120 (47%), Gaps = 17/120 (14%)
Query: 136 SAAAEQRSESPGRIRHLVHSVQ-----KLFTKSHSLEGSSKSNANGTKA-DGRADDHHHA 189
S E+RS S R+L SV+ + H G S+S+ + +++ G +H
Sbjct: 558 SKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGHDQKNHRK 617
Query: 190 HHAKH---SKRSKSKE------RKPEGKPRPGMSSW--WSSDDNLDSDSTYRTPSVLNRH 238
HH K SKRS+S+E R+ + + R SSW S +L S+ST R+ S + H
Sbjct: 618 HHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSESTSRSRSRSSDH 677
>gi|7705555 iroquois homeobox 4 [Homo sapiens]
Length = 519
Score = 35.8 bits (81), Expect = 0.20
Identities = 59/254 (23%), Positives = 93/254 (36%), Gaps = 29/254 (11%)
Query: 361 AMGDEESGESDSSPKTSPKSAILPEPLLKSIGQRPLGEHQTQTYLQAASDVPVGHSLDPA 420
A G+EE G + + + EPL S P+G+ + + L D + PA
Sbjct: 222 AEGEEEEGGEEEARE---------EPLKSSKNAEPVGKEEKELELSDLDDFDPLEAEPPA 272
Query: 421 ANYNSPKFRSRNQSYMRAVST----LSQASCVSQVSEAEING-QFESVCESVFSEVESQA 475
P F S + R + + +AS ++S A G + E S + S A
Sbjct: 273 CEL-KPPFHSLDGGLERVPAAPDGPVKEASGALRMSLAAGGGAALDEDLERARSCLRSAA 331
Query: 476 MDALDLPGCFRTRS--HSYLRAIQAGYSQDDECIPMMTPSDITSTIRSTAAVSYTN---- 529
LPG + L + AG S E P + T+T + AA S +
Sbjct: 332 AGPEPLPGAEGGPQVCEAKLGFVPAGASAGLEAKPRIWSLAHTATAAAAAATSLSQTEFP 391
Query: 530 ---YKKTPPPVPPRTTSKPLISVTAQSSTESTQDAYQDSRAQRMSPWPQDSRGLYNSTDS 586
K+ P P +S P S + D +QDS + W G+++ D
Sbjct: 392 SCMLKRQGPAAPAAVSSAPATSPSVALPHSGALDRHQDSPVTSLRNWVD---GVFH--DP 446
Query: 587 LDSNKAMNLALETA 600
+ + +N A TA
Sbjct: 447 ILRHSTLNQAWATA 460
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 35.8 bits (81), Expect = 0.20
Identities = 32/133 (24%), Positives = 54/133 (40%), Gaps = 2/133 (1%)
Query: 103 AKINRIPANLLDQFEKQLPLHRDGFHTLQYQRTSAAAEQRSESPGRIRHLVH--SVQKLF 160
A++NR P N ++Q P D + R+ + +E +S R H S +
Sbjct: 1285 ARLNRRPRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSS 1344
Query: 161 TKSHSLEGSSKSNANGTKADGRADDHHHAHHAKHSKRSKSKERKPEGKPRPGMSSWWSSD 220
T S+ S+S + G + GR ++ + S R+ S+ R P S +
Sbjct: 1345 TSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTY 1404
Query: 221 DNLDSDSTYRTPS 233
D+ S S R+ S
Sbjct: 1405 DSYYSRSRSRSRS 1417
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 35.4 bits (80), Expect = 0.26
Identities = 94/504 (18%), Positives = 170/504 (33%), Gaps = 49/504 (9%)
Query: 170 SKSNANGTKADGRADDHHHAHHAKHSKRSKSK--------ERKPEGKPRPGMSSWWSSDD 221
SK N NG+ + G DD + ++ S ++ GK + S SSD
Sbjct: 498 SKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDS 557
Query: 222 NLDSDSTYRTPSVLNRHHLGPVAHCYPDALQSPFGDLSLKTSKSNNDVKCSACEGLALTP 281
+ SDS+ + S + D+ S D S S ++D S + +
Sbjct: 558 SNSSDSSDSSDSDSS------------DSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSS 605
Query: 282 DAKYLKRSSWSTLTVSQAKEAYRKSSLNLDKPLLHQDAKPALRPCHYLQVPQDEWGGYPT 341
D+ SS S+ + ++ + S + D D+K D +
Sbjct: 606 DSSDSSDSSDSSDSSDSKSDSSKSESDSSD-----SDSK------------SDSSDSNSS 648
Query: 342 GGKDEEIPCRRMRSGSYIKAMGDEESGESDSSPKTSPKSAILPEPLLKSIGQRPLGEHQT 401
D S + + +S +S SS +S S + + +
Sbjct: 649 DSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSS 708
Query: 402 QTYLQAASDVPVGHSLDPAANYNSPKFRSRNQSYMRAVSTLSQASCVSQVSEAEINGQFE 461
+ +SD +S D ++ +S S N S S S +S S S++ +
Sbjct: 709 DSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSS 768
Query: 462 SVCESVFSEVESQAMDALDLPGCFRTRSHSYLRAIQAGYSQDDECIPMMTPSDITSTIRS 521
+S S S + D+ D S+S + + S SD + + S
Sbjct: 769 DSSDSSDSSDSSNSSDSND-------SSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSS 821
Query: 522 TAAVSYTNYKKTPPPVPPRTTSKPLISVTAQSSTESTQDAYQDSRAQRMSPWPQDSRGLY 581
++ S + + +S S + ++S DS S DS
Sbjct: 822 NSSDSSNSSDSS----DSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSS 877
Query: 582 NSTDSLDSNKAMNLALETAAAQRHLPESQSSSVRTSDKAILVSKAEELLKSRCSSIGIQD 641
+S+DS DSN++ N + +++ + S S +SD + + ++ S S
Sbjct: 878 DSSDSSDSNESSN-SSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSS 936
Query: 642 SEFPEHQPYPRSDVETATDSDTES 665
SD ++DS S
Sbjct: 937 DSSNSSDSSDSSDSSNSSDSSNSS 960
Score = 30.8 bits (68), Expect = 6.5
Identities = 91/514 (17%), Positives = 170/514 (33%), Gaps = 8/514 (1%)
Query: 163 SHSLEGSSKSNANGTKADGRADDHHHAHHAKHSKRSKSKERKPEGKPRPGMSSWWSSD-- 220
S+S + S SN++ + + D + + S S S S SSD
Sbjct: 789 SNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSS 848
Query: 221 DNLDSDSTYRTPSVLNRHHLGPVAHCYPDALQSPFGDLSLKTSKSNN-DVKCSACEGLAL 279
D DSDS+ R+ S + + + S D S SN+ D S+ +
Sbjct: 849 DGSDSDSSNRSDS----SNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSD 904
Query: 280 TPDAKYLKRSSWSTLTVSQAKEAYRKSSLNLDKPLLHQDAKPALRPCHYLQVPQDEWGGY 339
+ D+ SS S+ + ++ + + N D+ + +
Sbjct: 905 SSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSN 964
Query: 340 PTGGKDEEIPCRRMRSGSYIKAMGDEESGESDSSPKTSPKSAILPEPLLKSIGQRPLGEH 399
+ D S S + + S SDSS ++ + S
Sbjct: 965 SSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNS 1024
Query: 400 QTQTYLQAASDVPVGHSLDPAANYNSPKFRSRNQSYMRAVSTLSQASCVSQVSEAEINGQ 459
+ +SD +++ +S S N S S S +S S S++ + +
Sbjct: 1025 SDSSNSSDSSDSSDSSDSSDSSD-SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSE 1083
Query: 460 FESVCESVFSEVESQAMDALDLPGCFRTRSHSYLRAIQAGYSQDDECIPMMTPSDITSTI 519
+S S S + D+ D + S D + S+
Sbjct: 1084 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 1143
Query: 520 RSTAAVSYTNYKKTPPPVPPRTTSKPLISVTAQSSTESTQDAYQDSRAQRMSPWPQDSRG 579
S ++ S + + ++ S ++ SS S DS S DS
Sbjct: 1144 SSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1203
Query: 580 LYNSTDSLDSNKAMNLALETAAAQRHLPESQSSSVRTSDKAILVSKAEELLKSRCSSIGI 639
+S+DS DS+ + + + + ++ S S +SD + + ++ S S
Sbjct: 1204 SSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTS 1263
Query: 640 QDSEFPEHQPYPRSDVETATDSDTESRGLREYHS 673
++ + Q + +DSD++S G HS
Sbjct: 1264 DSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHS 1297
>gi|109255230 centrosomal protein 170kDa isoform beta [Homo sapiens]
Length = 1486
Score = 35.4 bits (80), Expect = 0.26
Identities = 54/223 (24%), Positives = 85/223 (38%), Gaps = 31/223 (13%)
Query: 47 SCPGGRHRCSPRSSV---HSECVMMPVVLGDHVSSSTFPRMHYSSHYDTRDDCAVAHAGA 103
S G RHR PR + +C +M + S + + H +YD D +
Sbjct: 10 SSGGTRHRL-PREMIFVGRDDCELM-------LQSRSVDKQHAVINYDASTDEHLVKDLG 61
Query: 104 KIN-------RIPANLLDQFEKQLPLHRDGFHTLQYQRTSAAAEQRSESPGRIRHLVHSV 156
+N RIP + + L R G+ T + T E R ++H ++
Sbjct: 62 SLNGTFVNDVRIPEQTYITLKLEDKL-RFGYDTNLF--TVVQGEMRVPEEA-LKHEKFTI 117
Query: 157 QKLFTKSHSLEGSSKSNANGTKADGRADDHHHAHHAKHSKRSKSKERK------PEGKPR 210
Q ++ S SKS A+ D + D K ++ KS+E+ P G P
Sbjct: 118 QLQLSQKSSESELSKS-ASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPL 176
Query: 211 PGMSSWWSSDDNLDSDSTYRT-PSVLNRHHLGPVAHCYPDALQ 252
G SWW DD +D ++T ++H + C DA Q
Sbjct: 177 YGQPSWW-GDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDAKQ 218
>gi|109255228 centrosomal protein 170kDa isoform alpha [Homo
sapiens]
Length = 1584
Score = 35.4 bits (80), Expect = 0.26
Identities = 54/223 (24%), Positives = 85/223 (38%), Gaps = 31/223 (13%)
Query: 47 SCPGGRHRCSPRSSV---HSECVMMPVVLGDHVSSSTFPRMHYSSHYDTRDDCAVAHAGA 103
S G RHR PR + +C +M + S + + H +YD D +
Sbjct: 10 SSGGTRHRL-PREMIFVGRDDCELM-------LQSRSVDKQHAVINYDASTDEHLVKDLG 61
Query: 104 KIN-------RIPANLLDQFEKQLPLHRDGFHTLQYQRTSAAAEQRSESPGRIRHLVHSV 156
+N RIP + + L R G+ T + T E R ++H ++
Sbjct: 62 SLNGTFVNDVRIPEQTYITLKLEDKL-RFGYDTNLF--TVVQGEMRVPEEA-LKHEKFTI 117
Query: 157 QKLFTKSHSLEGSSKSNANGTKADGRADDHHHAHHAKHSKRSKSKERK------PEGKPR 210
Q ++ S SKS A+ D + D K ++ KS+E+ P G P
Sbjct: 118 QLQLSQKSSESELSKS-ASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPL 176
Query: 211 PGMSSWWSSDDNLDSDSTYRT-PSVLNRHHLGPVAHCYPDALQ 252
G SWW DD +D ++T ++H + C DA Q
Sbjct: 177 YGQPSWW-GDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDAKQ 218
>gi|109255232 centrosomal protein 170kDa isoform gamma [Homo
sapiens]
Length = 1460
Score = 35.4 bits (80), Expect = 0.26
Identities = 54/223 (24%), Positives = 85/223 (38%), Gaps = 31/223 (13%)
Query: 47 SCPGGRHRCSPRSSV---HSECVMMPVVLGDHVSSSTFPRMHYSSHYDTRDDCAVAHAGA 103
S G RHR PR + +C +M + S + + H +YD D +
Sbjct: 10 SSGGTRHRL-PREMIFVGRDDCELM-------LQSRSVDKQHAVINYDASTDEHLVKDLG 61
Query: 104 KIN-------RIPANLLDQFEKQLPLHRDGFHTLQYQRTSAAAEQRSESPGRIRHLVHSV 156
+N RIP + + L R G+ T + T E R ++H ++
Sbjct: 62 SLNGTFVNDVRIPEQTYITLKLEDKL-RFGYDTNLF--TVVQGEMRVPEEA-LKHEKFTI 117
Query: 157 QKLFTKSHSLEGSSKSNANGTKADGRADDHHHAHHAKHSKRSKSKERK------PEGKPR 210
Q ++ S SKS A+ D + D K ++ KS+E+ P G P
Sbjct: 118 QLQLSQKSSESELSKS-ASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPL 176
Query: 211 PGMSSWWSSDDNLDSDSTYRT-PSVLNRHHLGPVAHCYPDALQ 252
G SWW DD +D ++T ++H + C DA Q
Sbjct: 177 YGQPSWW-GDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDAKQ 218
>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
Length = 1460
Score = 35.0 bits (79), Expect = 0.34
Identities = 94/465 (20%), Positives = 171/465 (36%), Gaps = 48/465 (10%)
Query: 313 PLLHQDAKPALRPCHYLQVPQ-DEWGGYPTGGKDEEIPCRRMRSGSYIKAMGDEESGESD 371
P ++ K + C L P+ D G P ++E P + +G +E S +
Sbjct: 311 PEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAG-------EEGSRREE 363
Query: 372 SSPKTSPKSAILPEPLLKSIGQRPLGEHQTQTYLQ--AASDVPVGHSLDPAANYNSPKFR 429
++ + K++ L E + + + EH + L ASD H LD FR
Sbjct: 364 AAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFG-------FR 416
Query: 430 SRNQSYMRAVSTLSQA---SCVSQVSEAEINGQFESVCESVFSEVESQAMDALD------ 480
SR ++ V LS +C I + +S +S E++S+ L+
Sbjct: 417 SRISEHLLDVDVLSPVLGGACRQAQQPLGIEDKDDS--QSSQDELQSKQSKGLEERLSPP 474
Query: 481 LPGCFRTRSHSYLRAIQAGYSQDDECIPMMTPSDITSTIRSTAAVSYTNYKKTPPPVPPR 540
LP R +S A + Q E P ++ + + + ++ P PP
Sbjct: 475 LPHEERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPA 534
Query: 541 TTSKPLISVTAQSSTESTQDAYQDSRAQ-RMSPWPQDSRGLYNSTDSL----DSNKAMNL 595
K + Q+ +D + +SP P S + ST+ + ++A
Sbjct: 535 ACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEV-RSTEPVAPPEQLSEAALK 593
Query: 596 ALETAAAQ------RHLPESQSSSVRTSDKAILVSKAEELLKSRCSSIGIQDSEFPEHQP 649
A+E A AQ RHL ES+ ++ + + + EE+L R Q +
Sbjct: 594 AMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEIL--RLHQQKEQSLSSLRERL 651
Query: 650 YPRSDVETATDSDTESR---GLREYHSVGVQVEDEKRHGRFKRSNSVTAAVQADLELEGF 706
+ E A + ES+ LR Q ++++ + S ++ +LE +
Sbjct: 652 QKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEAS---LQKLREELESQQK 708
Query: 707 PGHITTEDKGLQFGSSFQRHSEPSTPTQYSAVRTVRTQGLFSYRE 751
+ E K Q + E S ++ +A+ + + L RE
Sbjct: 709 AERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLRE 753
>gi|58530876 melanoma antigen family C, 1 [Homo sapiens]
Length = 1142
Score = 35.0 bits (79), Expect = 0.34
Identities = 68/327 (20%), Positives = 126/327 (38%), Gaps = 29/327 (8%)
Query: 368 GESDSSPKTSPKSAILPEPLLKSIGQRPLG-------EHQTQTYLQAASDVPVGHSLDPA 420
GE SP P+S + E S+ Q P+ Q++ +++ P G P
Sbjct: 602 GEDSMSPLYFPQSPLQGEEFQSSL-QSPVSICSSSTPSSLPQSFPESSQSPPEGPVQSPL 660
Query: 421 ANYNSPKFRSRNQSYMRAVSTLSQAS---CVSQVSEAEINGQFESVCESVFSEVESQAMD 477
+ SP +QS +++ + + Q+ ++ + G+ +S+ F + + D
Sbjct: 661 HSPQSPPEGMHSQSPLQSPESAPEGEDSLSPLQIPQSPLEGE-DSLSSLHFPQSPPEWED 719
Query: 478 ALDLPGCFRTRSHSYLRAIQAGYSQDDECIPMMTPSDITSTIRSTAAVSYTNYKKTPPPV 537
+L S L Q +D + +P I S+ ST+ ++ ++P
Sbjct: 720 SL-----------SPLHFPQFPPQGEDFQSSLQSPVSICSS--STSLSLPQSFPESPQSP 766
Query: 538 PPRTTSKPLISVTAQSSTESTQDAYQDSRAQRMSPWPQDSRG-LYNSTDSLDSNKAMNLA 596
P PL + + + Q S SP ++ L + S S+ + +L+
Sbjct: 767 PEGPAQSPLQRPVSSFFSYTLASLLQSSHESPQSPPEGPAQSPLQSPVSSFPSSTSSSLS 826
Query: 597 LETAAAQRHLPESQSSSV-RTSDKAILVSKAEELLKSRCSSIGIQDSEFPEHQPYPRSDV 655
+ + P S SSS+ ++S ++ L S S S ++S P + SD
Sbjct: 827 QSSPVSS--FPSSTSSSLSKSSPESPLQSPVISFSSSTSLSPFSEESSSPVDEYTSSSDT 884
Query: 656 ETATDSDTESRGLREYHSVGVQVEDEK 682
+DS T+S L E + DEK
Sbjct: 885 LLESDSLTDSESLIESEPLFTYTLDEK 911
>gi|54607124 RNA binding motif protein 15B [Homo sapiens]
Length = 890
Score = 34.7 bits (78), Expect = 0.45
Identities = 18/60 (30%), Positives = 32/60 (53%), Gaps = 10/60 (16%)
Query: 162 KSHSLEGSSKSNANG---TKADGRADDHHHAHH----AKHSKRSKSKERK---PEGKPRP 211
++HS EG+ +S++N ++ HHH HH + H K+++ ER E +P+P
Sbjct: 638 ENHSSEGTKESSSNSLSNSRHGAEERGHHHHHHEAADSSHGKKARDSERNHRTTEAEPKP 697
>gi|187828892 calcium channel, alpha 1A subunit isoform 4 [Homo
sapiens]
Length = 2506
Score = 34.3 bits (77), Expect = 0.58
Identities = 27/127 (21%), Positives = 47/127 (37%), Gaps = 2/127 (1%)
Query: 88 SHYDTRDDCAVAHAGAKINRIPANLLDQF--EKQLPLHRDGFHTLQYQRTSAAAEQRSES 145
++ T D + A + A LD + E+ P H + R+ A+E+
Sbjct: 2110 NNLSTISDTSPMKRSASVLGPKARRLDDYSLERVPPEENQRHHQRRRDRSHRASERSLGR 2169
Query: 146 PGRIRHLVHSVQKLFTKSHSLEGSSKSNANGTKADGRADDHHHAHHAKHSKRSKSKERKP 205
+ + + + T+S L + G D + HHH HH H K+R
Sbjct: 2170 YTDVDTGLGTDLSMTTQSGDLPSKERDQERGRPKDRKHRQHHHHHHHHHHPPPPDKDRYA 2229
Query: 206 EGKPRPG 212
+ +P G
Sbjct: 2230 QERPDHG 2236
>gi|187828880 calcium channel, alpha 1A subunit isoform 3 [Homo
sapiens]
Length = 2261
Score = 34.3 bits (77), Expect = 0.58
Identities = 27/127 (21%), Positives = 47/127 (37%), Gaps = 2/127 (1%)
Query: 88 SHYDTRDDCAVAHAGAKINRIPANLLDQF--EKQLPLHRDGFHTLQYQRTSAAAEQRSES 145
++ T D + A + A LD + E+ P H + R+ A+E+
Sbjct: 2111 NNLSTISDTSPMKRSASVLGPKARRLDDYSLERVPPEENQRHHQRRRDRSHRASERSLGR 2170
Query: 146 PGRIRHLVHSVQKLFTKSHSLEGSSKSNANGTKADGRADDHHHAHHAKHSKRSKSKERKP 205
+ + + + T+S L + G D + HHH HH H K+R
Sbjct: 2171 YTDVDTGLGTDLSMTTQSGDLPSKERDQERGRPKDRKHRQHHHHHHHHHHPPPPDKDRYA 2230
Query: 206 EGKPRPG 212
+ +P G
Sbjct: 2231 QERPDHG 2237
>gi|148612840 RUN and TBC1 domain containing 2 isoform 3 [Homo
sapiens]
Length = 1093
Score = 34.3 bits (77), Expect = 0.58
Identities = 59/245 (24%), Positives = 98/245 (40%), Gaps = 32/245 (13%)
Query: 595 LALETAAAQRHLPESQSSSVRTSDKAILVSKAEELLKSRCSSIGIQDSEFPEHQPYPRSD 654
L E QR ++ + S A L S +L R S+I + S+ R +
Sbjct: 607 LGCEAIVRQRERESHAAALAKCSSGASLDSHLHRMLH-RDSTISNESSQSCSSG---RQN 662
Query: 655 VETATDSDTESR---GLREYHSVGVQVEDEKRHGRFKRSNSVTAAVQADLELEGFPGHIT 711
+ +DS + ++ + E V + E++ + N V D GH +
Sbjct: 663 IRLHSDSSSSTQVFESVDEVEQVEAEGRLEEKQPKIPNGNLVNGTCSPD------SGHPS 716
Query: 712 TEDKGLQFGSSFQRHSEPSTPTQYSAVRTVR-TQGLFSYRE---DYRTQVDTSTLPPPDP 767
+ + F S HSEPS T+ S + R T + R+ D R + +T P
Sbjct: 717 SHN----FSSGLSEHSEPSLSTEDSVLDAQRNTPTVLRPRDGSVDDRQSSEATTSQDEAP 772
Query: 768 WLEPAI-DTVETGRMSPCRRD------GSWFLKLLHAETKRMEGW-CKEMEREAE---EN 816
E A+ D++E+ ++ D GS + L + MEGW E E+ + E+
Sbjct: 773 REELAVQDSLESDLLANESMDEFMSITGSLDMALPEKDDVVMEGWRSSETEKHGQADSED 832
Query: 817 DLSEE 821
+LSEE
Sbjct: 833 NLSEE 837
>gi|90577167 RUN and TBC1 domain containing 2 isoform 1 [Homo
sapiens]
Length = 1148
Score = 34.3 bits (77), Expect = 0.58
Identities = 59/245 (24%), Positives = 98/245 (40%), Gaps = 32/245 (13%)
Query: 595 LALETAAAQRHLPESQSSSVRTSDKAILVSKAEELLKSRCSSIGIQDSEFPEHQPYPRSD 654
L E QR ++ + S A L S +L R S+I + S+ R +
Sbjct: 662 LGCEAIVRQRERESHAAALAKCSSGASLDSHLHRMLH-RDSTISNESSQSCSSG---RQN 717
Query: 655 VETATDSDTESR---GLREYHSVGVQVEDEKRHGRFKRSNSVTAAVQADLELEGFPGHIT 711
+ +DS + ++ + E V + E++ + N V D GH +
Sbjct: 718 IRLHSDSSSSTQVFESVDEVEQVEAEGRLEEKQPKIPNGNLVNGTCSPD------SGHPS 771
Query: 712 TEDKGLQFGSSFQRHSEPSTPTQYSAVRTVR-TQGLFSYRE---DYRTQVDTSTLPPPDP 767
+ + F S HSEPS T+ S + R T + R+ D R + +T P
Sbjct: 772 SHN----FSSGLSEHSEPSLSTEDSVLDAQRNTPTVLRPRDGSVDDRQSSEATTSQDEAP 827
Query: 768 WLEPAI-DTVETGRMSPCRRD------GSWFLKLLHAETKRMEGW-CKEMEREAE---EN 816
E A+ D++E+ ++ D GS + L + MEGW E E+ + E+
Sbjct: 828 REELAVQDSLESDLLANESMDEFMSITGSLDMALPEKDDVVMEGWRSSETEKHGQADSED 887
Query: 817 DLSEE 821
+LSEE
Sbjct: 888 NLSEE 892
>gi|18641364 protein tyrosine phosphatase, receptor type, C isoform
3 precursor [Homo sapiens]
Length = 1256
Score = 33.9 bits (76), Expect = 0.76
Identities = 41/140 (29%), Positives = 55/140 (39%), Gaps = 11/140 (7%)
Query: 535 PPVPPRTTSKPLISVTAQSSTESTQDAYQDSRAQRMSPWPQDSRGLYNSTDSLDSNKAMN 594
P VP +S PL + T S ST + D S P D+ S DSLD+ A N
Sbjct: 39 PSVP--LSSDPLPTHTTAFSPASTFERENDFSETTTSLSP-DNTSTQVSPDSLDNASAFN 95
Query: 595 LALETAAAQRHLP---ESQSSSVRTSDKAILVSKAEELLKSRCSSIGIQD-----SEFPE 646
++ HLP +SQ+ S T + S A L S I D SE
Sbjct: 96 TTGVSSVQTPHLPTHADSQTPSAGTDTQTFSGSAANAKLNPTPGSNAISDAYLNASETTT 155
Query: 647 HQPYPRSDVETATDSDTESR 666
P + + T T + T S+
Sbjct: 156 LSPSGSAVISTTTIATTPSK 175
>gi|22209009 protein kinase CHK2 isoform b [Homo sapiens]
Length = 514
Score = 33.9 bits (76), Expect = 0.76
Identities = 33/118 (27%), Positives = 49/118 (41%), Gaps = 13/118 (11%)
Query: 678 VEDEKRHGRFKRSN---SVTAAVQADLELEGFPGHITTEDKGLQFGSSFQRHSEPSTPTQ 734
VE ++ HG S SVT + + + +G I++ SS HS T
Sbjct: 7 VEAQQSHGSSACSQPHGSVTQSQGSSSQSQG----ISSSSTSTMPNSSQSSHSSSGT--- 59
Query: 735 YSAVRTVRTQGLFSYREDYRTQVDTSTLPPPDPWLEPAIDTVETGRMS-PCRRDGSWF 791
S++ TV TQ L+S ED + P P PW + ++ G + C D WF
Sbjct: 60 LSSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWAR--LWALQDGFANLECVNDNYWF 115
>gi|6005850 protein kinase CHK2 isoform a [Homo sapiens]
Length = 543
Score = 33.9 bits (76), Expect = 0.76
Identities = 33/118 (27%), Positives = 49/118 (41%), Gaps = 13/118 (11%)
Query: 678 VEDEKRHGRFKRSN---SVTAAVQADLELEGFPGHITTEDKGLQFGSSFQRHSEPSTPTQ 734
VE ++ HG S SVT + + + +G I++ SS HS T
Sbjct: 7 VEAQQSHGSSACSQPHGSVTQSQGSSSQSQG----ISSSSTSTMPNSSQSSHSSSGT--- 59
Query: 735 YSAVRTVRTQGLFSYREDYRTQVDTSTLPPPDPWLEPAIDTVETGRMS-PCRRDGSWF 791
S++ TV TQ L+S ED + P P PW + ++ G + C D WF
Sbjct: 60 LSSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWAR--LWALQDGFANLECVNDNYWF 115
>gi|167736355 mucin 4 isoform a [Homo sapiens]
Length = 5284
Score = 33.9 bits (76), Expect = 0.76
Identities = 64/298 (21%), Positives = 108/298 (36%), Gaps = 25/298 (8%)
Query: 340 PTGGKDEEIPCRRMRSGSYIKAMGDEESGESDSSPKTSPKSAILPEPLLKSIGQRPLGEH 399
P+GG + S + G E + +S TSP +A ++ G+
Sbjct: 726 PSGGTSLSKTGALTLANSVVSTPGGPEGQWTSASASTSPDTAAAMTHTHQAESTEASGQT 785
Query: 400 QTQTYLQAASDVPVGHSLDPAANYNSPKFRSRNQSYMRAVSTLSQASCVSQVSEA-EING 458
QT + S + P+++ S S ++ + T +S S+ S +
Sbjct: 786 QTSEPASSGSRTTSAGTATPSSSGASGTTPSGSEGISTSGETTRFSSNPSRDSHTTQSTT 845
Query: 459 QFESVCESVFSEVESQAMDALDLPGCFR-TRSHSYLRAIQAGYS---------QDDECIP 508
+ S S + S M + +PG F T S + G S Q+ I
Sbjct: 846 ELLSASASHGAIPVSTGMASSIVPGTFHPTLSEASTAGRPTGQSSPTSPSASPQETAAIS 905
Query: 509 MMTPSDITSTIRSTAAVSY----TNYKKTPPPVPPRTTSKPLISVTAQSSTESTQDA--- 561
M + T T R + +S T+ T PP PP TS L S ++ T S +
Sbjct: 906 RMAQTQRTRTSRGSDTISLASQATDTFSTVPPTPPSITSTGLTSPQTETHTLSPSGSGKT 965
Query: 562 YQDSRAQRMSPWPQDSRGLYNSTDSLDSNKAMNLALETAAAQRH---LPESQSSSVRT 616
+ + +P P Y S+ S +++ ++ + H LP + SSV T
Sbjct: 966 FTTALISNATPLPV----TYASSASTGHTTPLHVTDASSVSTGHATPLPVTSPSSVST 1019
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.127 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,094,659
Number of Sequences: 37866
Number of extensions: 2163928
Number of successful extensions: 8290
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 132
Number of HSP's that attempted gapping in prelim test: 7841
Number of HSP's gapped (non-prelim): 429
length of query: 975
length of database: 18,247,518
effective HSP length: 112
effective length of query: 863
effective length of database: 14,006,526
effective search space: 12087631938
effective search space used: 12087631938
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.