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Search of human proteins with 38201714
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38201714 ELAV-like 1 [Homo sapiens]
(326 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38201714 ELAV-like 1 [Homo sapiens] 657 0.0
gi|115511032 ELAV (embryonic lethal, abnormal vision, Drosophila... 491 e-139
gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens] 487 e-138
gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens] 487 e-138
gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens] 487 e-138
gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens] 487 e-138
gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens] 481 e-136
gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens] 465 e-131
gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens] 462 e-130
gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo s... 124 9e-29
gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens] 119 4e-27
gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s... 115 4e-26
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho... 115 5e-26
gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo... 115 5e-26
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho... 115 5e-26
gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens] 112 6e-25
gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens] 108 6e-24
gi|4506447 RNA binding motif, single stranded interacting protei... 103 2e-22
gi|8400718 RNA binding motif, single stranded interacting protei... 103 2e-22
gi|4506449 RNA binding motif, single stranded interacting protei... 103 2e-22
gi|51317355 RNA binding motif, single stranded interacting prote... 101 8e-22
gi|51317353 RNA binding motif, single stranded interacting prote... 101 8e-22
gi|51317351 RNA binding motif, single stranded interacting prote... 101 8e-22
gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens] 97 1e-20
gi|188219593 TIA1 protein isoform 1 [Homo sapiens] 97 2e-20
gi|188219591 TIA1 protein isoform 2 [Homo sapiens] 93 4e-19
gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens] 92 5e-19
gi|109948285 poly(A) binding protein, cytoplasmic 1-like 2B [Hom... 87 3e-17
gi|61175237 poly(A) binding protein, cytoplasmic 1-like 2A [Homo... 87 3e-17
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 86 3e-17
>gi|38201714 ELAV-like 1 [Homo sapiens]
Length = 326
Score = 657 bits (1694), Expect = 0.0
Identities = 326/326 (100%), Positives = 326/326 (100%)
Query: 1 MSNGYEDHMAEDCRGDIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHS 60
MSNGYEDHMAEDCRGDIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHS
Sbjct: 1 MSNGYEDHMAEDCRGDIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHS 60
Query: 61 LGYGFVNYVTAKDAERAINTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQK 120
LGYGFVNYVTAKDAERAINTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQK
Sbjct: 61 LGYGFVNYVTAKDAERAINTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQK 120
Query: 121 DVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPIT 180
DVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPIT
Sbjct: 121 DVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPIT 180
Query: 181 VKFAANPNQNKNVALLSQLYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNA 240
VKFAANPNQNKNVALLSQLYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNA
Sbjct: 181 VKFAANPNQNKNVALLSQLYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNA 240
Query: 241 SSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAM 300
SSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAM
Sbjct: 241 SSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAM 300
Query: 301 AIASLNGYRLGDKILQVSFKTNKSHK 326
AIASLNGYRLGDKILQVSFKTNKSHK
Sbjct: 301 AIASLNGYRLGDKILQVSFKTNKSHK 326
>gi|115511032 ELAV (embryonic lethal, abnormal vision,
Drosophila)-like 2 (Hu antigen B) [Homo sapiens]
Length = 359
Score = 491 bits (1264), Expect = e-139
Identities = 237/321 (73%), Positives = 274/321 (85%), Gaps = 13/321 (4%)
Query: 19 RTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAI 78
+TNLIVNYLPQNMTQ+EL+SLF SIGE+ES KL+RDK+ G SLGYGFVNY+ KDAE+AI
Sbjct: 38 KTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAI 97
Query: 79 NTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVL 138
NTLNGLRLQ+KTIKVSYARPSS I+DANLY+SGLP+TMTQK++E +FS++GRII SR+L
Sbjct: 98 NTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 157
Query: 139 VDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVALLSQ 198
VDQ TG+SRGV FIRFDKR EAEEAI NG KPPG++EPITVKFA NP+Q N A+LSQ
Sbjct: 158 VDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQKTNQAILSQ 217
Query: 199 LYHSPARRFGGPVHHQAQRF-------------RFSPMGVDHMSGLSGVNVPGNASSGWC 245
LY SP RR+ GP+ QAQRF RFSPM +D M+ L+G+N+PG+ +GWC
Sbjct: 218 LYQSPNRRYPGPLAQQAQRFRLDNLLNMAYGVKRFSPMTIDGMTSLAGINIPGHPGTGWC 277
Query: 246 IFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASL 305
IF+YNL DADE ILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNY+EAAMAIASL
Sbjct: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
Query: 306 NGYRLGDKILQVSFKTNKSHK 326
NGYRLGD++LQVSFKTNK+HK
Sbjct: 338 NGYRLGDRVLQVSFKTNKTHK 358
Score = 58.9 bits (141), Expect = 6e-09
Identities = 37/101 (36%), Positives = 52/101 (51%), Gaps = 2/101 (1%)
Query: 10 AEDCRGDIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYV 69
A I NL V+ LP+ MTQ EL LFS G + +++++ D+V G S G GF+ +
Sbjct: 115 ARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFD 174
Query: 70 TAKDAERAINTLNGLRLQSKT--IKVSYARPSSEVIKDANL 108
+AE AI LNG + T I V +A S+ A L
Sbjct: 175 KRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQKTNQAIL 215
>gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens]
Length = 369
Score = 487 bits (1253), Expect = e-138
Identities = 234/324 (72%), Positives = 273/324 (84%), Gaps = 13/324 (4%)
Query: 16 DIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAE 75
D +TNLIVNYLPQNMTQ+E RSLF SIGE+ES KL+RDK+ G SLGYGFVNY+ KDAE
Sbjct: 45 DDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAE 104
Query: 76 RAINTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINS 135
+AINTLNGLRLQ+KTIKVSYARPSS I+DANLY+SGLP+TMTQK++E +FS++GRII S
Sbjct: 105 KAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITS 164
Query: 136 RVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVAL 195
R+LVDQ TG+SRGV FIRFDKR EAEEAI NG KP G++EPITVKFA NP+Q + AL
Sbjct: 165 RILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQAL 224
Query: 196 LSQLYHSPARRFGGPVHHQAQRF-------------RFSPMGVDHMSGLSGVNVPGNASS 242
LSQLY SP RR+ GP+HHQAQRF RFSP+ +D M+ L G+N+PG+ +
Sbjct: 225 LSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPGHTGT 284
Query: 243 GWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAI 302
GWCIF+YNL D+DE +LWQ+FGPFGAV NVKVIRDFNTNKCKGFGFVTMTNY+EAAMAI
Sbjct: 285 GWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAI 344
Query: 303 ASLNGYRLGDKILQVSFKTNKSHK 326
ASLNGYRLGD++LQVSFKTNK+HK
Sbjct: 345 ASLNGYRLGDRVLQVSFKTNKAHK 368
Score = 59.3 bits (142), Expect = 4e-09
Identities = 54/193 (27%), Positives = 90/193 (46%), Gaps = 13/193 (6%)
Query: 10 AEDCRGDIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYV 69
A I NL V+ LP+ MTQ EL LFS G + +++++ D+V G S G GF+ +
Sbjct: 125 ARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFD 184
Query: 70 TAKDAERAINTLNGLRLQSKT--IKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFS 127
+AE AI LNG + T I V +A S+ K + +S L ++ ++ +
Sbjct: 185 KRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQ--KSSQALLSQLYQSPNRRYPGPLHH 242
Query: 128 RFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANP 187
+ R +D ++ GV RF + + +TS G PG + F N
Sbjct: 243 Q-----AQRFRLDNLLNMAYGVK--RFSPIT--IDGMTSLVGMNIPGHTGTGWCIFVYNL 293
Query: 188 NQNKNVALLSQLY 200
+ + + ++L QL+
Sbjct: 294 SPDSDESVLWQLF 306
>gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens]
Length = 366
Score = 487 bits (1253), Expect = e-138
Identities = 234/324 (72%), Positives = 273/324 (84%), Gaps = 13/324 (4%)
Query: 16 DIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAE 75
D +TNLIVNYLPQNMTQ+E RSLF SIGE+ES KL+RDK+ G SLGYGFVNY+ KDAE
Sbjct: 42 DDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAE 101
Query: 76 RAINTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINS 135
+AINTLNGLRLQ+KTIKVSYARPSS I+DANLY+SGLP+TMTQK++E +FS++GRII S
Sbjct: 102 KAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITS 161
Query: 136 RVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVAL 195
R+LVDQ TG+SRGV FIRFDKR EAEEAI NG KP G++EPITVKFA NP+Q + AL
Sbjct: 162 RILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQAL 221
Query: 196 LSQLYHSPARRFGGPVHHQAQRF-------------RFSPMGVDHMSGLSGVNVPGNASS 242
LSQLY SP RR+ GP+HHQAQRF RFSP+ +D M+ L G+N+PG+ +
Sbjct: 222 LSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPGHTGT 281
Query: 243 GWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAI 302
GWCIF+YNL D+DE +LWQ+FGPFGAV NVKVIRDFNTNKCKGFGFVTMTNY+EAAMAI
Sbjct: 282 GWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAI 341
Query: 303 ASLNGYRLGDKILQVSFKTNKSHK 326
ASLNGYRLGD++LQVSFKTNK+HK
Sbjct: 342 ASLNGYRLGDRVLQVSFKTNKAHK 365
Score = 59.3 bits (142), Expect = 4e-09
Identities = 54/193 (27%), Positives = 90/193 (46%), Gaps = 13/193 (6%)
Query: 10 AEDCRGDIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYV 69
A I NL V+ LP+ MTQ EL LFS G + +++++ D+V G S G GF+ +
Sbjct: 122 ARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFD 181
Query: 70 TAKDAERAINTLNGLRLQSKT--IKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFS 127
+AE AI LNG + T I V +A S+ K + +S L ++ ++ +
Sbjct: 182 KRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQ--KSSQALLSQLYQSPNRRYPGPLHH 239
Query: 128 RFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANP 187
+ R +D ++ GV RF + + +TS G PG + F N
Sbjct: 240 Q-----AQRFRLDNLLNMAYGVK--RFSPIT--IDGMTSLVGMNIPGHTGTGWCIFVYNL 290
Query: 188 NQNKNVALLSQLY 200
+ + + ++L QL+
Sbjct: 291 SPDSDESVLWQLF 303
>gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens]
Length = 383
Score = 487 bits (1253), Expect = e-138
Identities = 234/324 (72%), Positives = 273/324 (84%), Gaps = 13/324 (4%)
Query: 16 DIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAE 75
D +TNLIVNYLPQNMTQ+E RSLF SIGE+ES KL+RDK+ G SLGYGFVNY+ KDAE
Sbjct: 59 DDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAE 118
Query: 76 RAINTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINS 135
+AINTLNGLRLQ+KTIKVSYARPSS I+DANLY+SGLP+TMTQK++E +FS++GRII S
Sbjct: 119 KAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITS 178
Query: 136 RVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVAL 195
R+LVDQ TG+SRGV FIRFDKR EAEEAI NG KP G++EPITVKFA NP+Q + AL
Sbjct: 179 RILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQAL 238
Query: 196 LSQLYHSPARRFGGPVHHQAQRF-------------RFSPMGVDHMSGLSGVNVPGNASS 242
LSQLY SP RR+ GP+HHQAQRF RFSP+ +D M+ L G+N+PG+ +
Sbjct: 239 LSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPGHTGT 298
Query: 243 GWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAI 302
GWCIF+YNL D+DE +LWQ+FGPFGAV NVKVIRDFNTNKCKGFGFVTMTNY+EAAMAI
Sbjct: 299 GWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAI 358
Query: 303 ASLNGYRLGDKILQVSFKTNKSHK 326
ASLNGYRLGD++LQVSFKTNK+HK
Sbjct: 359 ASLNGYRLGDRVLQVSFKTNKAHK 382
Score = 59.3 bits (142), Expect = 4e-09
Identities = 54/193 (27%), Positives = 90/193 (46%), Gaps = 13/193 (6%)
Query: 10 AEDCRGDIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYV 69
A I NL V+ LP+ MTQ EL LFS G + +++++ D+V G S G GF+ +
Sbjct: 139 ARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFD 198
Query: 70 TAKDAERAINTLNGLRLQSKT--IKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFS 127
+AE AI LNG + T I V +A S+ K + +S L ++ ++ +
Sbjct: 199 KRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQ--KSSQALLSQLYQSPNRRYPGPLHH 256
Query: 128 RFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANP 187
+ R +D ++ GV RF + + +TS G PG + F N
Sbjct: 257 Q-----AQRFRLDNLLNMAYGVK--RFSPIT--IDGMTSLVGMNIPGHTGTGWCIFVYNL 307
Query: 188 NQNKNVALLSQLY 200
+ + + ++L QL+
Sbjct: 308 SPDSDESVLWQLF 320
>gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens]
Length = 366
Score = 487 bits (1253), Expect = e-138
Identities = 234/324 (72%), Positives = 273/324 (84%), Gaps = 13/324 (4%)
Query: 16 DIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAE 75
D +TNLIVNYLPQNMTQ+E RSLF SIGE+ES KL+RDK+ G SLGYGFVNY+ KDAE
Sbjct: 42 DDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAE 101
Query: 76 RAINTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINS 135
+AINTLNGLRLQ+KTIKVSYARPSS I+DANLY+SGLP+TMTQK++E +FS++GRII S
Sbjct: 102 KAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITS 161
Query: 136 RVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVAL 195
R+LVDQ TG+SRGV FIRFDKR EAEEAI NG KP G++EPITVKFA NP+Q + AL
Sbjct: 162 RILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQAL 221
Query: 196 LSQLYHSPARRFGGPVHHQAQRF-------------RFSPMGVDHMSGLSGVNVPGNASS 242
LSQLY SP RR+ GP+HHQAQRF RFSP+ +D M+ L G+N+PG+ +
Sbjct: 222 LSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPGHTGT 281
Query: 243 GWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAI 302
GWCIF+YNL D+DE +LWQ+FGPFGAV NVKVIRDFNTNKCKGFGFVTMTNY+EAAMAI
Sbjct: 282 GWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAI 341
Query: 303 ASLNGYRLGDKILQVSFKTNKSHK 326
ASLNGYRLGD++LQVSFKTNK+HK
Sbjct: 342 ASLNGYRLGDRVLQVSFKTNKAHK 365
Score = 59.3 bits (142), Expect = 4e-09
Identities = 54/193 (27%), Positives = 90/193 (46%), Gaps = 13/193 (6%)
Query: 10 AEDCRGDIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYV 69
A I NL V+ LP+ MTQ EL LFS G + +++++ D+V G S G GF+ +
Sbjct: 122 ARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFD 181
Query: 70 TAKDAERAINTLNGLRLQSKT--IKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFS 127
+AE AI LNG + T I V +A S+ K + +S L ++ ++ +
Sbjct: 182 KRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQ--KSSQALLSQLYQSPNRRYPGPLHH 239
Query: 128 RFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANP 187
+ R +D ++ GV RF + + +TS G PG + F N
Sbjct: 240 Q-----AQRFRLDNLLNMAYGVK--RFSPIT--IDGMTSLVGMNIPGHTGTGWCIFVYNL 290
Query: 188 NQNKNVALLSQLY 200
+ + + ++L QL+
Sbjct: 291 SPDSDESVLWQLF 303
>gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens]
Length = 380
Score = 481 bits (1239), Expect = e-136
Identities = 234/338 (69%), Positives = 273/338 (80%), Gaps = 27/338 (7%)
Query: 16 DIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAE 75
D +TNLIVNYLPQNMTQ+E RSLF SIGE+ES KL+RDK+ G SLGYGFVNY+ KDAE
Sbjct: 42 DDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAE 101
Query: 76 RAINTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINS 135
+AINTLNGLRLQ+KTIKVSYARPSS I+DANLY+SGLP+TMTQK++E +FS++GRII S
Sbjct: 102 KAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITS 161
Query: 136 RVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVAL 195
R+LVDQ TG+SRGV FIRFDKR EAEEAI NG KP G++EPITVKFA NP+Q + AL
Sbjct: 162 RILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQAL 221
Query: 196 LSQLYHSPARRFGGPVHHQAQRF---------------------------RFSPMGVDHM 228
LSQLY SP RR+ GP+HHQAQRF RFSP+ +D M
Sbjct: 222 LSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRLMSGPVPPSACPPRFSPITIDGM 281
Query: 229 SGLSGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFG 288
+ L G+N+PG+ +GWCIF+YNL D+DE +LWQ+FGPFGAV NVKVIRDFNTNKCKGFG
Sbjct: 282 TSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFG 341
Query: 289 FVTMTNYEEAAMAIASLNGYRLGDKILQVSFKTNKSHK 326
FVTMTNY+EAAMAIASLNGYRLGD++LQVSFKTNK+HK
Sbjct: 342 FVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKAHK 379
>gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens]
Length = 360
Score = 465 bits (1196), Expect = e-131
Identities = 226/325 (69%), Positives = 268/325 (82%), Gaps = 14/325 (4%)
Query: 16 DIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAE 75
D +TNLIVNYLPQNMTQDE +SLF SIG++ES KL+RDK+ G SLGYGFVNY DA+
Sbjct: 35 DDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDAD 94
Query: 76 RAINTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINS 135
+AINTLNGL+LQ+KTIKVSYARPSS I+DANLY+SGLP+TM+QK++E +FS++GRII S
Sbjct: 95 KAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITS 154
Query: 136 RVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVAL 195
R+LVDQ TG+SRGV FIRFDKR EAEEAI NG KP G++EPITVKFA NP+Q AL
Sbjct: 155 RILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQAL 214
Query: 196 LSQLYHSPARRFGGPVHHQAQRF-------------RFSPMGVDHMSGLSGVNVPGNAS- 241
L+ LY S ARR+ GP+HHQ QRF RFSP+ +D MSGL+GV + G A+
Sbjct: 215 LTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKRFSPIAIDGMSGLAGVGLSGGAAG 274
Query: 242 SGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMA 301
+GWCIF+YNL +ADE +LWQ+FGPFGAVTNVKVIRDF TNKCKGFGFVTMTNY+EAAMA
Sbjct: 275 AGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMA 334
Query: 302 IASLNGYRLGDKILQVSFKTNKSHK 326
IASLNGYRLG+++LQVSFKT+K HK
Sbjct: 335 IASLNGYRLGERVLQVSFKTSKQHK 359
Score = 55.1 bits (131), Expect = 8e-08
Identities = 43/150 (28%), Positives = 70/150 (46%), Gaps = 13/150 (8%)
Query: 10 AEDCRGDIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYV 69
A I NL V+ LP+ M+Q E+ LFS G + +++++ D+V G S G GF+ +
Sbjct: 115 ARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFD 174
Query: 70 TAKDAERAINTLNGLRL--QSKTIKVSYARPSSEVIKDA---NLYISGLPRTMTQKDVED 124
+AE AI LNG + ++ I V +A S+ A +LY S R +
Sbjct: 175 KRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTHLYQSSARRYAGPLHHQT 234
Query: 125 MFSRFGRIIN--------SRVLVDQTTGLS 146
R ++N S + +D +GL+
Sbjct: 235 QRFRLDNLLNMAYGVKRFSPIAIDGMSGLA 264
>gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens]
Length = 367
Score = 462 bits (1189), Expect = e-130
Identities = 226/332 (68%), Positives = 268/332 (80%), Gaps = 21/332 (6%)
Query: 16 DIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAE 75
D +TNLIVNYLPQNMTQDE +SLF SIG++ES KL+RDK+ G SLGYGFVNY DA+
Sbjct: 35 DDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDAD 94
Query: 76 RAINTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINS 135
+AINTLNGL+LQ+KTIKVSYARPSS I+DANLY+SGLP+TM+QK++E +FS++GRII S
Sbjct: 95 KAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITS 154
Query: 136 RVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVAL 195
R+LVDQ TG+SRGV FIRFDKR EAEEAI NG KP G++EPITVKFA NP+Q AL
Sbjct: 155 RILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQAL 214
Query: 196 LSQLYHSPARRFGGPVHHQAQRF--------------------RFSPMGVDHMSGLSGVN 235
L+ LY S ARR+ GP+HHQ QRF RFSP+ +D MSGL+GV
Sbjct: 215 LTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKSPLSLIARFSPIAIDGMSGLAGVG 274
Query: 236 VPGNAS-SGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTN 294
+ G A+ +GWCIF+YNL +ADE +LWQ+FGPFGAVTNVKVIRDF TNKCKGFGFVTMTN
Sbjct: 275 LSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTN 334
Query: 295 YEEAAMAIASLNGYRLGDKILQVSFKTNKSHK 326
Y+EAAMAIASLNGYRLG+++LQVSFKT+K HK
Sbjct: 335 YDEAAMAIASLNGYRLGERVLQVSFKTSKQHK 366
Score = 54.7 bits (130), Expect = 1e-07
Identities = 32/94 (34%), Positives = 51/94 (54%), Gaps = 2/94 (2%)
Query: 10 AEDCRGDIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYV 69
A I NL V+ LP+ M+Q E+ LFS G + +++++ D+V G S G GF+ +
Sbjct: 115 ARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFD 174
Query: 70 TAKDAERAINTLNGLRL--QSKTIKVSYARPSSE 101
+AE AI LNG + ++ I V +A S+
Sbjct: 175 KRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQ 208
>gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo
sapiens]
Length = 614
Score = 124 bits (312), Expect = 9e-29
Identities = 86/317 (27%), Positives = 152/317 (47%), Gaps = 47/317 (14%)
Query: 18 GRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERA 77
G N+ + L ++ L FS+ G + S K+ D+ S G+GFV++ T + A++A
Sbjct: 97 GVGNIFIKNLEDSIDNKALYDTFSTFGNILSCKVACDEHG--SRGFGFVHFETHEAAQQA 154
Query: 78 INTLNGLRLQSKTIKVSY--------ARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRF 129
INT+NG+ L + + V + A + ++ N+Y+ LP + ++ ++D+FS+F
Sbjct: 155 INTMNGMLLNDRKVFVGHFKSRREREAELGARALEFTNIYVKNLPVDVDEQGLQDLFSQF 214
Query: 130 GRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQ 189
G++++ +V+ D +G SR F+ F+K EA++A+ NG + G +
Sbjct: 215 GKMLSVKVMRD-NSGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSG-------RLLYAGRA 266
Query: 190 NKNVALLSQLYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNASSGWCIFIY 249
K V ++L + RF M D + GVN +++
Sbjct: 267 QKRVERQNEL-----------------KRRFEQMKQDRLRRYQGVN----------LYVK 299
Query: 250 NLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYR 309
NL D+ L + F P+G +T+ KV+ + KGFGFV ++ EEA A+ +NG
Sbjct: 300 NLDDSIDDDKLRKEFSPYGVITSAKVMTE--GGHSKGFGFVCFSSPEEATKAVTEMNGRI 357
Query: 310 LGDKILQVSFKTNKSHK 326
+G K L V+ K +
Sbjct: 358 VGTKPLYVALAQRKEER 374
Score = 110 bits (275), Expect = 2e-24
Identities = 81/297 (27%), Positives = 140/297 (47%), Gaps = 49/297 (16%)
Query: 21 NLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINT 80
+L V L ++T+ L FS G + S ++ RD SLGY ++N+ DAERA++T
Sbjct: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDT 71
Query: 81 LNGLRLQSKTIKVSYARPSSEVIKD--ANLYISGLPRTMTQKDVEDMFSRFGRIINSRVL 138
+N L+ + I++ +++ + K N++I L ++ K + D FS FG I++ +V
Sbjct: 72 MNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILSCKVA 131
Query: 139 VDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVALLSQ 198
D+ SRG F+ F+ A++AI + NG
Sbjct: 132 CDEHG--SRGFGFVHFETHEAAQQAINTMNG----------------------------- 160
Query: 199 LYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNASSGWCIFIYNLGQDADEG 258
+ + + F G H +++R R + +G + + I++ NL D DE
Sbjct: 161 MLLNDRKVFVG--HFKSRREREAELGARALEFTN-------------IYVKNLPVDVDEQ 205
Query: 259 ILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYRLGDKIL 315
L +F FG + +VKV+RD N+ + FGFV +EEA A+ +NG + ++L
Sbjct: 206 GLQDLFSQFGKMLSVKVMRD-NSGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSGRLL 261
Score = 77.0 bits (188), Expect = 2e-14
Identities = 54/199 (27%), Positives = 97/199 (48%), Gaps = 25/199 (12%)
Query: 20 TNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAIN 79
TN+ V LP ++ + L+ LFS G++ S K++RD +GHS +GFVN+ ++A++A+
Sbjct: 191 TNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDN-SGHSRCFGFVNFEKHEEAQKAVV 249
Query: 80 TLNGLRLQSKTIKVSYARPSSEVIKD------------------ANLYISGLPRTMTQKD 121
+NG + + + A+ E + NLY+ L ++
Sbjct: 250 HMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDK 309
Query: 122 VEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITV 181
+ FS +G I +++V+ + G S+G F+ F EA +A+T NG ++P+ V
Sbjct: 310 LRKEFSPYGVITSAKVMTEG--GHSKGFGFVCFSSPEEATKAVTEMNGRIV--GTKPLYV 365
Query: 182 KFAANPNQNKNVALLSQLY 200
A + K A+L+ Y
Sbjct: 366 ALAQRKEERK--AILTNQY 382
Score = 60.1 bits (144), Expect = 3e-09
Identities = 61/223 (27%), Positives = 93/223 (41%), Gaps = 55/223 (24%)
Query: 106 ANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAIT 165
A+LY+ L +T+ + + FS G I++ RV D T S G A+I F + ++AE A+
Sbjct: 11 ASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALD 70
Query: 166 SFNGHKPPGSSEPITVKFAA-NPNQNKNVALLSQLYHSPARRFGGPVHHQAQRFRFSPMG 224
+ N G +PI + ++ +P K
Sbjct: 71 TMNFEMLKG--QPIRIMWSQRDPGLRK--------------------------------- 95
Query: 225 VDHMSGLSGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKC 284
SGV GN IFI NL D L+ F FG + + KV D + ++
Sbjct: 96 -------SGV---GN------IFIKNLEDSIDNKALYDTFSTFGNILSCKVACDEHGSR- 138
Query: 285 KGFGFVTMTNYEEAAMAIASLNGYRLGD-KILQVSFKTNKSHK 326
GFGFV +E A AI ++NG L D K+ FK+ + +
Sbjct: 139 -GFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRRERE 180
>gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]
Length = 636
Score = 119 bits (298), Expect = 4e-27
Identities = 85/318 (26%), Positives = 150/318 (47%), Gaps = 49/318 (15%)
Query: 18 GRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERA 77
G N+ + L +++ L FS+ G + S K++ D+ S GYGFV++ T + AERA
Sbjct: 97 GVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYGFVHFETQEAAERA 154
Query: 78 INTLNGLRLQSKTI--------KVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRF 129
I +NG+ L + + K A + + N+YI M + ++D+F +F
Sbjct: 155 IEKMNGMLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKF 214
Query: 130 GRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQ 189
G ++ +V+ D+ +G S+G F+ F++ +A++A+ NG + G
Sbjct: 215 GPALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVDEMNGKELNG--------------- 258
Query: 190 NKNVALLSQLYHSPARRFGGPVHHQAQ-RFRFSPMGVDHMSGLSGVNVPGNASSGWCIFI 248
Q+Y A++ V Q + + +F M D ++ GVN +++
Sbjct: 259 -------KQIYVGRAQK---KVERQTELKRKFEQMKQDRITRYQGVN----------LYV 298
Query: 249 YNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGY 308
NL D+ L + F PFG +T+ KV+ + + KGFGFV ++ EEA A+ +NG
Sbjct: 299 KNLDDGIDDERLRKEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEEATKAVTEMNGR 356
Query: 309 RLGDKILQVSFKTNKSHK 326
+ K L V+ K +
Sbjct: 357 IVATKPLYVALAQRKEER 374
Score = 87.8 bits (216), Expect = 1e-17
Identities = 49/151 (32%), Positives = 85/151 (56%), Gaps = 4/151 (2%)
Query: 21 NLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINT 80
+L V L ++T+ L FS G + S ++ RD + SLGY +VN+ DAERA++T
Sbjct: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
Query: 81 LNGLRLQSKTIKVSYAR--PSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVL 138
+N ++ K +++ +++ PS N++I L +++ K + D FS FG I++ +V+
Sbjct: 72 MNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
Query: 139 VDQTTGLSRGVAFIRFDKRSEAEEAITSFNG 169
D+ S+G F+ F+ + AE AI NG
Sbjct: 132 CDENG--SKGYGFVHFETQEAAERAIEKMNG 160
Score = 72.4 bits (176), Expect = 5e-13
Identities = 65/266 (24%), Positives = 116/266 (43%), Gaps = 51/266 (19%)
Query: 98 PSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKR 157
PS+ A+LY+ L +T+ + + FS G I++ RV D T S G A++ F +
Sbjct: 3 PSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQP 62
Query: 158 SEAEEAITSFNGHKPPGSSEPITVKFA-ANPN-----------QNKNVALLSQLYHSPAR 205
++AE A+ + N G +P+ + ++ +P+ +N + ++ ++ +
Sbjct: 63 ADAERALDTMNFDVIKG--KPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFS 120
Query: 206 RFG-----------------GPVHHQAQRFRFSPMGVDHMSGL----------------- 231
FG G VH + Q + ++ M+G+
Sbjct: 121 AFGNILSCKVVCDENGSKGYGFVHFETQ--EAAERAIEKMNGMLLNDRKVFVGRFKSRKE 178
Query: 232 SGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVT 291
+ A ++I N G+D D+ L +FG FG +VKV+ D + K KGFGFV+
Sbjct: 179 REAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTD-ESGKSKGFGFVS 237
Query: 292 MTNYEEAAMAIASLNGYRLGDKILQV 317
+E+A A+ +NG L K + V
Sbjct: 238 FERHEDAQKAVDEMNGKELNGKQIYV 263
>gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
sapiens]
Length = 370
Score = 115 bits (289), Expect = 4e-26
Identities = 81/299 (27%), Positives = 147/299 (49%), Gaps = 49/299 (16%)
Query: 21 NLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINT 80
+L V L ++T+D L FS++G V S ++ RD+V SLGY +VN++ DA++A++T
Sbjct: 11 SLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDT 70
Query: 81 LNGLRLQSKTIKVSYARPSSEVIKD--ANLYISGLPRTMTQKDVEDMFSRFGRIINSRVL 138
+N ++ K+I++ +++ + + + N++I L +++ K + + FS FG+I++S+V+
Sbjct: 71 MNFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSKVM 130
Query: 139 VDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVALLSQ 198
D S+G AF+ F +S A+ AI NG G
Sbjct: 131 SDDQG--SKGYAFVHFQNQSAADRAIEEMNGKLLKG------------------------ 164
Query: 199 LYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNASSGWCIFIYNLGQDADEG 258
+ F G ++ R + AS ++I N G D D+
Sbjct: 165 -----CKVFVGRFKNRKDR---------------EAELRSKASEFTNVYIKNFGGDMDDE 204
Query: 259 ILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYRLGDKILQV 317
L +F +G +VKV+ D ++ K KGFGFV+ ++E A A+ +NG + +++ V
Sbjct: 205 RLKDVFSKYGKTLSVKVMTD-SSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFV 262
Score = 99.4 bits (246), Expect = 4e-21
Identities = 78/309 (25%), Positives = 140/309 (45%), Gaps = 47/309 (15%)
Query: 18 GRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERA 77
G N+ + L +++ L FS+ G++ S+K++ D S GY FV++ A+RA
Sbjct: 96 GIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQG--SKGYAFVHFQNQSAADRA 153
Query: 78 INTLNGLRLQS--------KTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRF 129
I +NG L+ K K A S+ + N+YI M + ++D+FS++
Sbjct: 154 IEEMNGKLLKGCKVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDERLKDVFSKY 213
Query: 130 GRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQ 189
G+ ++ +V+ D ++G S+G F+ FD A++A+ NG G + +
Sbjct: 214 GKTLSVKVMTD-SSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQ----LIFVGRAQKK 268
Query: 190 NKNVALLSQLYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNASSGWCIFIY 249
+ A L Q++ R + + G GV ++I
Sbjct: 269 VERQAELKQMFEQLKR--------------------ERIRGCQGVK----------LYIK 298
Query: 250 NLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYR 309
NL D+ L F FG+++ VKV+++ + KGFG + ++ E+A A+ +NG
Sbjct: 299 NLDDTIDDEKLRNEFSSFGSISRVKVMQE--EGQSKGFGLICFSSPEDATKAMTEMNGRI 356
Query: 310 LGDKILQVS 318
LG K L ++
Sbjct: 357 LGSKPLSIA 365
Score = 70.1 bits (170), Expect = 3e-12
Identities = 52/183 (28%), Positives = 87/183 (47%), Gaps = 23/183 (12%)
Query: 20 TNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAIN 79
TN+ + +M + L+ +FS G+ S K++ D +G S G+GFV++ + + A++A+
Sbjct: 190 TNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDS-SGKSKGFGFVSFDSHEAAKKAVE 248
Query: 80 TLNGLRLQSKTIKVSYARPSSE------------------VIKDANLYISGLPRTMTQKD 121
+NG + + I V A+ E + LYI L T+ +
Sbjct: 249 EMNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDDEK 308
Query: 122 VEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITV 181
+ + FS FG I SRV V Q G S+G I F +A +A+T NG S+P+++
Sbjct: 309 LRNEFSSFGSI--SRVKVMQEEGQSKGFGLICFSSPEDATKAMTEMNGRIL--GSKPLSI 364
Query: 182 KFA 184
A
Sbjct: 365 ALA 367
Score = 53.9 bits (128), Expect = 2e-07
Identities = 56/222 (25%), Positives = 90/222 (40%), Gaps = 53/222 (23%)
Query: 106 ANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAIT 165
A+LY+ L +T+ + FS G +++ R+ DQ T S G A++ F + ++A++A+
Sbjct: 10 ASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALD 69
Query: 166 SFNGHKPPGSSEPITVKFAANPNQNKNVALLSQLYHSPARRFGGPVHHQAQRFRFSPMGV 225
+ N G K++ L+ + RR
Sbjct: 70 TMNFDIIKG----------------KSIRLMWSQRDAYLRR------------------- 94
Query: 226 DHMSGLSGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCK 285
SG+ GN +FI NL + D L++ F FG + + KV+ D K
Sbjct: 95 ------SGI---GN------VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSD--DQGSK 137
Query: 286 GFGFVTMTNYEEAAMAIASLNGYRL-GDKILQVSFKTNKSHK 326
G+ FV N A AI +NG L G K+ FK K +
Sbjct: 138 GYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDRE 179
Score = 47.0 bits (110), Expect = 2e-05
Identities = 27/93 (29%), Positives = 51/93 (54%), Gaps = 3/93 (3%)
Query: 5 YEDHMAEDCRGDIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYG 64
+E E RG G L + L + ++LR+ FSS G + K+++++ G S G+G
Sbjct: 279 FEQLKRERIRGCQG-VKLYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQEE--GQSKGFG 335
Query: 65 FVNYVTAKDAERAINTLNGLRLQSKTIKVSYAR 97
+ + + +DA +A+ +NG L SK + ++ A+
Sbjct: 336 LICFSSPEDATKAMTEMNGRILGSKPLSIALAQ 368
>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
sapiens]
Length = 631
Score = 115 bits (288), Expect = 5e-26
Identities = 85/299 (28%), Positives = 147/299 (49%), Gaps = 49/299 (16%)
Query: 21 NLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINT 80
+L V L ++T+ L FS G V S ++ RD + SLGY +VN+ DAERA++T
Sbjct: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
Query: 81 LNGLRLQSKTIKVSYARPSSEVIKDA--NLYISGLPRTMTQKDVEDMFSRFGRIINSRVL 138
+N ++ K I++ +++ + K N++I L +++ K + D FS FG I++ +V+
Sbjct: 72 MNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
Query: 139 VDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVALLSQ 198
D+ S+G AF+ F+ + A++AI + N LL+
Sbjct: 132 CDENG--SKGYAFVHFETQEAADKAI------------------------EKMNGMLLND 165
Query: 199 LYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNASSGWCIFIYNLGQDADEG 258
+ F G ++++ R + +G A ++I N G++ D+
Sbjct: 166 -----RKVFVG--RFKSRKEREAELGA-------------KAKEFTNVYIKNFGEEVDDE 205
Query: 259 ILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYRLGDKILQV 317
L ++F FG +VKV+RD N K KGFGFV+ +E+A A+ +NG + KI+ V
Sbjct: 206 SLKELFSQFGKTLSVKVMRDPN-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFV 263
Score = 112 bits (279), Expect = 6e-25
Identities = 81/318 (25%), Positives = 149/318 (46%), Gaps = 49/318 (15%)
Query: 18 GRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERA 77
G N+ + L +++ L FS+ G + S K++ D+ S GY FV++ T + A++A
Sbjct: 97 GVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKA 154
Query: 78 INTLNGLRLQSKTI--------KVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRF 129
I +NG+ L + + K A ++ + N+YI + + ++++FS+F
Sbjct: 155 IEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQF 214
Query: 130 GRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQ 189
G+ ++ +V+ D G S+G F+ ++K +A +A+ NG + G + F +
Sbjct: 215 GKTLSVKVMRDPN-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGK-----IIFVGRAQK 268
Query: 190 NKNVALLSQLYHSPARRFGGPVHHQAQ-RFRFSPMGVDHMSGLSGVNVPGNASSGWCIFI 248
V QA+ + +F + + +S GVN ++I
Sbjct: 269 K--------------------VERQAELKRKFEQLKQERISRYQGVN----------LYI 298
Query: 249 YNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGY 308
NL D+ L + F PFG++T+ KV+ + + KGFGFV ++ EEA A+ +NG
Sbjct: 299 KNLDDTIDDEKLRKEFSPFGSITSAKVMLE--DGRSKGFGFVCFSSPEEATKAVTEMNGR 356
Query: 309 RLGDKILQVSFKTNKSHK 326
+G K L V+ K +
Sbjct: 357 IVGSKPLYVALAQRKEER 374
Score = 83.6 bits (205), Expect = 2e-16
Identities = 56/190 (29%), Positives = 90/190 (47%), Gaps = 23/190 (12%)
Query: 20 TNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAIN 79
TN+ + + + + L+ LFS G+ S K++RD G S G+GFV+Y +DA +A+
Sbjct: 191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVE 249
Query: 80 TLNGLRLQSKTIKVSYARPSSE------------------VIKDANLYISGLPRTMTQKD 121
+NG + K I V A+ E + NLYI L T+ +
Sbjct: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEK 309
Query: 122 VEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITV 181
+ FS FG I +++V+++ G S+G F+ F EA +A+T NG S+P+ V
Sbjct: 310 LRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEMNGRIV--GSKPLYV 365
Query: 182 KFAANPNQNK 191
A + K
Sbjct: 366 ALAQRKEERK 375
>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
sapiens]
Length = 644
Score = 115 bits (288), Expect = 5e-26
Identities = 85/299 (28%), Positives = 147/299 (49%), Gaps = 49/299 (16%)
Query: 21 NLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINT 80
+L V L ++T+ L FS G V S ++ RD + SLGY +VN+ DAERA++T
Sbjct: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
Query: 81 LNGLRLQSKTIKVSYARPSSEVIKDA--NLYISGLPRTMTQKDVEDMFSRFGRIINSRVL 138
+N ++ K I++ +++ + K N++I L +++ K + D FS FG I++ +V+
Sbjct: 72 MNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
Query: 139 VDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVALLSQ 198
D+ S+G AF+ F+ + A++AI + N LL+
Sbjct: 132 CDENG--SKGYAFVHFETQEAADKAI------------------------EKMNGMLLND 165
Query: 199 LYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNASSGWCIFIYNLGQDADEG 258
+ F G ++++ R + +G A ++I N G++ D+
Sbjct: 166 -----RKVFVG--RFKSRKEREAELGA-------------KAKEFTNVYIKNFGEEVDDE 205
Query: 259 ILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYRLGDKILQV 317
L ++F FG +VKV+RD N K KGFGFV+ +E+A A+ +NG + KI+ V
Sbjct: 206 SLKELFSQFGKTLSVKVMRDPN-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFV 263
Score = 112 bits (279), Expect = 6e-25
Identities = 81/318 (25%), Positives = 149/318 (46%), Gaps = 49/318 (15%)
Query: 18 GRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERA 77
G N+ + L +++ L FS+ G + S K++ D+ S GY FV++ T + A++A
Sbjct: 97 GVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKA 154
Query: 78 INTLNGLRLQSKTI--------KVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRF 129
I +NG+ L + + K A ++ + N+YI + + ++++FS+F
Sbjct: 155 IEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQF 214
Query: 130 GRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQ 189
G+ ++ +V+ D G S+G F+ ++K +A +A+ NG + G + F +
Sbjct: 215 GKTLSVKVMRDPN-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGK-----IIFVGRAQK 268
Query: 190 NKNVALLSQLYHSPARRFGGPVHHQAQ-RFRFSPMGVDHMSGLSGVNVPGNASSGWCIFI 248
V QA+ + +F + + +S GVN ++I
Sbjct: 269 K--------------------VERQAELKRKFEQLKQERISRYQGVN----------LYI 298
Query: 249 YNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGY 308
NL D+ L + F PFG++T+ KV+ + + KGFGFV ++ EEA A+ +NG
Sbjct: 299 KNLDDTIDDEKLRKEFSPFGSITSAKVMLE--DGRSKGFGFVCFSSPEEATKAVTEMNGR 356
Query: 309 RLGDKILQVSFKTNKSHK 326
+G K L V+ K +
Sbjct: 357 IVGSKPLYVALAQRKEER 374
Score = 83.6 bits (205), Expect = 2e-16
Identities = 56/190 (29%), Positives = 90/190 (47%), Gaps = 23/190 (12%)
Query: 20 TNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAIN 79
TN+ + + + + L+ LFS G+ S K++RD G S G+GFV+Y +DA +A+
Sbjct: 191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVE 249
Query: 80 TLNGLRLQSKTIKVSYARPSSE------------------VIKDANLYISGLPRTMTQKD 121
+NG + K I V A+ E + NLYI L T+ +
Sbjct: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEK 309
Query: 122 VEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITV 181
+ FS FG I +++V+++ G S+G F+ F EA +A+T NG S+P+ V
Sbjct: 310 LRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEMNGRIV--GSKPLYV 365
Query: 182 KFAANPNQNK 191
A + K
Sbjct: 366 ALAQRKEERK 375
>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
sapiens]
Length = 660
Score = 115 bits (288), Expect = 5e-26
Identities = 85/299 (28%), Positives = 147/299 (49%), Gaps = 49/299 (16%)
Query: 21 NLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINT 80
+L V L ++T+ L FS G V S ++ RD + SLGY +VN+ DAERA++T
Sbjct: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
Query: 81 LNGLRLQSKTIKVSYARPSSEVIKDA--NLYISGLPRTMTQKDVEDMFSRFGRIINSRVL 138
+N ++ K I++ +++ + K N++I L +++ K + D FS FG I++ +V+
Sbjct: 72 MNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
Query: 139 VDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVALLSQ 198
D+ S+G AF+ F+ + A++AI + N LL+
Sbjct: 132 CDENG--SKGYAFVHFETQEAADKAI------------------------EKMNGMLLND 165
Query: 199 LYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNASSGWCIFIYNLGQDADEG 258
+ F G ++++ R + +G A ++I N G++ D+
Sbjct: 166 -----RKVFVG--RFKSRKEREAELGA-------------KAKEFTNVYIKNFGEEVDDE 205
Query: 259 ILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYRLGDKILQV 317
L ++F FG +VKV+RD N K KGFGFV+ +E+A A+ +NG + KI+ V
Sbjct: 206 SLKELFSQFGKTLSVKVMRDPN-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFV 263
Score = 112 bits (279), Expect = 6e-25
Identities = 81/318 (25%), Positives = 149/318 (46%), Gaps = 49/318 (15%)
Query: 18 GRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERA 77
G N+ + L +++ L FS+ G + S K++ D+ S GY FV++ T + A++A
Sbjct: 97 GVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKA 154
Query: 78 INTLNGLRLQSKTI--------KVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRF 129
I +NG+ L + + K A ++ + N+YI + + ++++FS+F
Sbjct: 155 IEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQF 214
Query: 130 GRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQ 189
G+ ++ +V+ D G S+G F+ ++K +A +A+ NG + G + F +
Sbjct: 215 GKTLSVKVMRDPN-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGK-----IIFVGRAQK 268
Query: 190 NKNVALLSQLYHSPARRFGGPVHHQAQ-RFRFSPMGVDHMSGLSGVNVPGNASSGWCIFI 248
V QA+ + +F + + +S GVN ++I
Sbjct: 269 K--------------------VERQAELKRKFEQLKQERISRYQGVN----------LYI 298
Query: 249 YNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGY 308
NL D+ L + F PFG++T+ KV+ + + KGFGFV ++ EEA A+ +NG
Sbjct: 299 KNLDDTIDDEKLRKEFSPFGSITSAKVMLE--DGRSKGFGFVCFSSPEEATKAVTEMNGR 356
Query: 309 RLGDKILQVSFKTNKSHK 326
+G K L V+ K +
Sbjct: 357 IVGSKPLYVALAQRKEER 374
Score = 83.6 bits (205), Expect = 2e-16
Identities = 56/190 (29%), Positives = 90/190 (47%), Gaps = 23/190 (12%)
Query: 20 TNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAIN 79
TN+ + + + + L+ LFS G+ S K++RD G S G+GFV+Y +DA +A+
Sbjct: 191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVE 249
Query: 80 TLNGLRLQSKTIKVSYARPSSE------------------VIKDANLYISGLPRTMTQKD 121
+NG + K I V A+ E + NLYI L T+ +
Sbjct: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEK 309
Query: 122 VEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITV 181
+ FS FG I +++V+++ G S+G F+ F EA +A+T NG S+P+ V
Sbjct: 310 LRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEMNGRIV--GSKPLYV 365
Query: 182 KFAANPNQNK 191
A + K
Sbjct: 366 ALAQRKEERK 375
>gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]
Length = 631
Score = 112 bits (279), Expect = 6e-25
Identities = 86/318 (27%), Positives = 147/318 (46%), Gaps = 49/318 (15%)
Query: 18 GRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERA 77
G N+ V L +++ L S+ G + S ++ D+ S GYGFV++ T + AERA
Sbjct: 97 GVGNIFVKNLDKSINNKALYDTVSAFGNILSCNVVCDE--NGSKGYGFVHFETHEAAERA 154
Query: 78 INTLNGLRL--------QSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRF 129
I +NG+ L Q K+ K A + + N+YI M + ++D+F +F
Sbjct: 155 IKKMNGMLLNGRKVFVGQFKSRKEREAELGARAKEFPNVYIKNFGEDMDDERLKDLFGKF 214
Query: 130 GRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQ 189
G ++ +V+ D+ +G S+G F+ F++ +A++A+ NG + G
Sbjct: 215 GPALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVDEMNGKELNG--------------- 258
Query: 190 NKNVALLSQLYHSPARRFGGPVHHQAQRFR-FSPMGVDHMSGLSGVNVPGNASSGWCIFI 248
Q+Y A++ V Q + R F M D ++ VN +++
Sbjct: 259 -------KQIYVGRAQK---KVERQTELKRTFEQMKQDRITRYQVVN----------LYV 298
Query: 249 YNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGY 308
NL D+ L + F PFG +T+ KV+ + + KGFGFV ++ EEA A+ +NG
Sbjct: 299 KNLDDGIDDERLRKAFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEEATKAVTEMNGR 356
Query: 309 RLGDKILQVSFKTNKSHK 326
+ K L V+ K +
Sbjct: 357 IVATKPLYVALAQRKEER 374
Score = 79.7 bits (195), Expect = 3e-15
Identities = 45/151 (29%), Positives = 80/151 (52%), Gaps = 4/151 (2%)
Query: 21 NLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINT 80
+L V L ++T+ L FS G + S ++ RD + S Y +VN+ KDAE A++T
Sbjct: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALDT 71
Query: 81 LNGLRLQSKTIKVSYAR--PSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVL 138
+N ++ K +++ +++ PS N+++ L +++ K + D S FG I++ V+
Sbjct: 72 MNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNKALYDTVSAFGNILSCNVV 131
Query: 139 VDQTTGLSRGVAFIRFDKRSEAEEAITSFNG 169
D+ S+G F+ F+ AE AI NG
Sbjct: 132 CDENG--SKGYGFVHFETHEAAERAIKKMNG 160
Score = 67.8 bits (164), Expect = 1e-11
Identities = 64/264 (24%), Positives = 111/264 (42%), Gaps = 47/264 (17%)
Query: 98 PSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKR 157
PS+ A+LY+ L +T+ + + FS G I++ R+ D T S A++ F
Sbjct: 3 PSTPSYPTASLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHT 62
Query: 158 SEAEEAITSFNGHKPPGSSEPITVKFA-ANPN-----------QNKNVALLSQLYHSPAR 205
+AE A+ + N G +P+ + ++ +P+ +N + ++ ++ +
Sbjct: 63 KDAEHALDTMNFDVIKG--KPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNKALYDTVS 120
Query: 206 RFG-----------------GPVH---HQAQRFRFSPMGVDHMSGLS------------G 233
FG G VH H+A M ++G
Sbjct: 121 AFGNILSCNVVCDENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFKSRKERE 180
Query: 234 VNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMT 293
+ A ++I N G+D D+ L +FG FG +VKV+ D + K KGFGFV+
Sbjct: 181 AELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTD-ESGKSKGFGFVSFE 239
Query: 294 NYEEAAMAIASLNGYRLGDKILQV 317
+E+A A+ +NG L K + V
Sbjct: 240 RHEDAQKAVDEMNGKELNGKQIYV 263
>gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens]
Length = 382
Score = 108 bits (270), Expect = 6e-24
Identities = 85/298 (28%), Positives = 136/298 (45%), Gaps = 48/298 (16%)
Query: 22 LIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINTL 81
L V L ++T+D L F G + ++ RD V LGYG+VN+ DAE A+NT+
Sbjct: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
Query: 82 NGLRLQSKTIKVSYARPSSEVIKD--ANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLV 139
N + K ++ +++P + K N++I L +++ + + +FS FG I++ +V+
Sbjct: 80 NFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNILSCKVVC 139
Query: 140 DQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVALLSQL 199
D S+G A++ FD + A AI NG + N+ V +
Sbjct: 140 DDNG--SKGYAYVHFDSLAAANRAIWHMNGVR----------------LNNRQVYV---- 177
Query: 200 YHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNASSGWCIFIYNLGQDADEGI 259
RF P A+ V + NV F+ N+G D D+
Sbjct: 178 -----GRFKFPEERAAE--------VRTRDRATFTNV----------FVKNIGDDIDDEK 214
Query: 260 LWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYRLGDKILQV 317
L ++F +G +VKVIRD + K KGFGFV +E A A+ L+G + K+L V
Sbjct: 215 LKELFCEYGPTESVKVIRD-ASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYV 271
Score = 87.4 bits (215), Expect = 2e-17
Identities = 74/310 (23%), Positives = 140/310 (45%), Gaps = 48/310 (15%)
Query: 18 GRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERA 77
G N+ + L +++ L LFS+ G + S K++ D S GY +V++ + A RA
Sbjct: 104 GVGNIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDD--NGSKGYAYVHFDSLAAANRA 161
Query: 78 INTLNGLRLQSKTIKVSYARPSSEVIKD---------ANLYISGLPRTMTQKDVEDMFSR 128
I +NG+RL ++ + V + E + N+++ + + + ++++F
Sbjct: 162 IWHMNGVRLNNRQVYVGRFKFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCE 221
Query: 129 FGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPN 188
+G + +V+ D +G S+G F+R++ A++A+ +G G K
Sbjct: 222 YGPTESVKVIRD-ASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDG-------KVLYVGR 273
Query: 189 QNKNVALLSQLYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNASSGWCIFI 248
K + L++L R RF + + S GV I+I
Sbjct: 274 AQKKIERLAEL-----------------RRRFERLRLKEKSRPPGVP----------IYI 306
Query: 249 YNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGY 308
NL + ++ L + F FG+++ KV+ + + KGFG V +++EEA A+ +NG
Sbjct: 307 KNLDETINDEKLKEEFSSFGSISRAKVMME--VGQGKGFGVVCFSSFEEATKAVDEMNGR 364
Query: 309 RLGDKILQVS 318
+G K L V+
Sbjct: 365 IVGSKPLHVT 374
>gi|4506447 RNA binding motif, single stranded interacting protein 1
isoform c [Homo sapiens]
Length = 403
Score = 103 bits (258), Expect = 2e-22
Identities = 65/186 (34%), Positives = 100/186 (53%), Gaps = 21/186 (11%)
Query: 17 IGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAER 76
+ +TNL + LP + T +L L G++ S K I DK GYGFV++ + A++
Sbjct: 59 LSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQK 118
Query: 77 AINTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSR 136
A++ L +Q++ K P+ NLYIS LP +M ++++E+M FG++I++R
Sbjct: 119 AVSALKASGVQAQMAKQQEQDPT-------NLYISNLPLSMDEQELENMLKPFGQVISTR 171
Query: 137 VLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNG---HKPPGSS---EPITVKFA------ 184
+L D ++G SRGV F R + + E I FNG PPG S EP+ KFA
Sbjct: 172 ILRD-SSGTSRGVGFARMESTEKCEAVIGHFNGKFIKTPPGVSAPTEPLLCKFADGGQKK 230
Query: 185 -ANPNQ 189
NPN+
Sbjct: 231 RQNPNK 236
Score = 44.7 bits (104), Expect = 1e-04
Identities = 25/80 (31%), Positives = 41/80 (51%), Gaps = 6/80 (7%)
Query: 232 SGVNVPGNASSGWC------IFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCK 285
S N +++SGW ++I L + L ++ P+G + + K I D TNKCK
Sbjct: 44 SNNNSSSSSNSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCK 103
Query: 286 GFGFVTMTNYEEAAMAIASL 305
G+GFV + A A+++L
Sbjct: 104 GYGFVDFDSPAAAQKAVSAL 123
Score = 39.3 bits (90), Expect = 0.005
Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 246 IFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASL 305
++I NL DE L M PFG V + +++RD ++ +G GF M + E+ I
Sbjct: 143 LYISNLPLSMDEQELENMLKPFGQVISTRILRD-SSGTSRGVGFARMESTEKCEAVIGHF 201
Query: 306 NG 307
NG
Sbjct: 202 NG 203
>gi|8400718 RNA binding motif, single stranded interacting protein 1
isoform a [Homo sapiens]
Length = 406
Score = 103 bits (258), Expect = 2e-22
Identities = 65/186 (34%), Positives = 100/186 (53%), Gaps = 21/186 (11%)
Query: 17 IGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAER 76
+ +TNL + LP + T +L L G++ S K I DK GYGFV++ + A++
Sbjct: 59 LSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQK 118
Query: 77 AINTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSR 136
A++ L +Q++ K P+ NLYIS LP +M ++++E+M FG++I++R
Sbjct: 119 AVSALKASGVQAQMAKQQEQDPT-------NLYISNLPLSMDEQELENMLKPFGQVISTR 171
Query: 137 VLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNG---HKPPGSS---EPITVKFA------ 184
+L D ++G SRGV F R + + E I FNG PPG S EP+ KFA
Sbjct: 172 ILRD-SSGTSRGVGFARMESTEKCEAVIGHFNGKFIKTPPGVSAPTEPLLCKFADGGQKK 230
Query: 185 -ANPNQ 189
NPN+
Sbjct: 231 RQNPNK 236
Score = 44.7 bits (104), Expect = 1e-04
Identities = 25/80 (31%), Positives = 41/80 (51%), Gaps = 6/80 (7%)
Query: 232 SGVNVPGNASSGWC------IFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCK 285
S N +++SGW ++I L + L ++ P+G + + K I D TNKCK
Sbjct: 44 SNNNSSSSSNSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCK 103
Query: 286 GFGFVTMTNYEEAAMAIASL 305
G+GFV + A A+++L
Sbjct: 104 GYGFVDFDSPAAAQKAVSAL 123
Score = 39.3 bits (90), Expect = 0.005
Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 246 IFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASL 305
++I NL DE L M PFG V + +++RD ++ +G GF M + E+ I
Sbjct: 143 LYISNLPLSMDEQELENMLKPFGQVISTRILRD-SSGTSRGVGFARMESTEKCEAVIGHF 201
Query: 306 NG 307
NG
Sbjct: 202 NG 203
>gi|4506449 RNA binding motif, single stranded interacting protein 2
[Homo sapiens]
Length = 407
Score = 103 bits (257), Expect = 2e-22
Identities = 64/183 (34%), Positives = 97/183 (53%), Gaps = 15/183 (8%)
Query: 17 IGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAER 76
+ +TNL + L T +L L G++ S K I DK GYGFV++ + A++
Sbjct: 53 LSKTNLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQK 112
Query: 77 AINTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSR 136
A+ L +Q++ K P+ NLYIS LP +M ++++E M FG++I++R
Sbjct: 113 AVTALKASGVQAQMAKQQEQDPT-------NLYISNLPLSMDEQELEGMLKPFGQVISTR 165
Query: 137 VLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNG---HKPPG---SSEPITVKFA-ANPNQ 189
+L D T+G SRGV F R + + E IT FNG PPG S+P+ KFA P +
Sbjct: 166 ILRD-TSGTSRGVGFARMESTEKCEAIITHFNGKYIKTPPGVPAPSDPLLCKFADGGPKK 224
Query: 190 NKN 192
+N
Sbjct: 225 RQN 227
Score = 53.1 bits (126), Expect = 3e-07
Identities = 44/208 (21%), Positives = 80/208 (38%), Gaps = 60/208 (28%)
Query: 100 SEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSE 159
++ + NLYI GL T +D+ + +G+I++++ ++D+TT +G F+ FD S
Sbjct: 50 NDQLSKTNLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSA 109
Query: 160 AEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVALLSQLYHSPARRFGGPVHHQAQRFR 219
A++A+T+ + + + A Q+ +S L
Sbjct: 110 AQKAVTAL-------KASGVQAQMAKQQEQDPTNLYISNL-------------------- 142
Query: 220 FSPMGVDHMSGLSGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDF 279
P+ +D E L M PFG V + +++RD
Sbjct: 143 --PLSMD------------------------------EQELEGMLKPFGQVISTRILRD- 169
Query: 280 NTNKCKGFGFVTMTNYEEAAMAIASLNG 307
+ +G GF M + E+ I NG
Sbjct: 170 TSGTSRGVGFARMESTEKCEAIITHFNG 197
>gi|51317355 RNA binding motif, single stranded interacting protein
3 isoform 1 [Homo sapiens]
Length = 437
Score = 101 bits (252), Expect = 8e-22
Identities = 64/190 (33%), Positives = 101/190 (53%), Gaps = 15/190 (7%)
Query: 2 SNGYEDHMAEDCRGD-IGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHS 60
+N ++ + + G+ + +TNL + LP T +L L G++ S K I DK
Sbjct: 42 TNSSSNNSSNNSSGEQLSKTNLYIRGLPPGTTDQDLIKLCQPYGKIVSTKAILDKNTNQC 101
Query: 61 LGYGFVNYVTAKDAERAINTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQK 120
GYGFV++ + A++A+ +L +Q++ K P+ NLYIS LP +M ++
Sbjct: 102 KGYGFVDFDSPAAAQKAVASLKANGVQAQMAKQQEQDPT-------NLYISNLPISMDEQ 154
Query: 121 DVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNG---HKPPG--- 174
++E+M FG +I++R+L D G+SRGV F R + + E I FNG PPG
Sbjct: 155 ELENMLKPFGHVISTRILRD-ANGVSRGVGFARMESTEKCEVVIQHFNGKYLKTPPGIPA 213
Query: 175 SSEPITVKFA 184
SEP+ KFA
Sbjct: 214 PSEPLLCKFA 223
Score = 47.0 bits (110), Expect = 2e-05
Identities = 31/89 (34%), Positives = 43/89 (48%), Gaps = 5/89 (5%)
Query: 222 PMGVDHMSGLSGVNVPGNASSG-----WCIFIYNLGQDADEGILWQMFGPFGAVTNVKVI 276
PM S S N N SSG ++I L + L ++ P+G + + K I
Sbjct: 34 PMAPPSPSTNSSSNNSSNNSSGEQLSKTNLYIRGLPPGTTDQDLIKLCQPYGKIVSTKAI 93
Query: 277 RDFNTNKCKGFGFVTMTNYEEAAMAIASL 305
D NTN+CKG+GFV + A A+ASL
Sbjct: 94 LDKNTNQCKGYGFVDFDSPAAAQKAVASL 122
Score = 45.4 bits (106), Expect = 7e-05
Identities = 47/209 (22%), Positives = 71/209 (33%), Gaps = 60/209 (28%)
Query: 99 SSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRS 158
S E + NLYI GLP T +D+ + +G+I++++ ++D+
Sbjct: 54 SGEQLSKTNLYIRGLPPGTTDQDLIKLCQPYGKIVSTKAILDK----------------- 96
Query: 159 EAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVALLSQLYHSPARRFGGPVHHQAQRF 218
N NQ K + F P Q
Sbjct: 97 ---------------------------NTNQCKGYGFVD---------FDSPAAAQKAVA 120
Query: 219 RFSPMGVDHMSGLSGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRD 278
GV P N ++I NL DE L M PFG V + +++RD
Sbjct: 121 SLKANGVQAQMAKQQEQDPTN------LYISNLPISMDEQELENMLKPFGHVISTRILRD 174
Query: 279 FNTNKCKGFGFVTMTNYEEAAMAIASLNG 307
N +G GF M + E+ + I NG
Sbjct: 175 AN-GVSRGVGFARMESTEKCEVVIQHFNG 202
>gi|51317353 RNA binding motif, single stranded interacting protein
3 isoform 3 [Homo sapiens]
Length = 419
Score = 101 bits (252), Expect = 8e-22
Identities = 64/190 (33%), Positives = 101/190 (53%), Gaps = 15/190 (7%)
Query: 2 SNGYEDHMAEDCRGD-IGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHS 60
+N ++ + + G+ + +TNL + LP T +L L G++ S K I DK
Sbjct: 41 TNSSSNNSSNNSSGEQLSKTNLYIRGLPPGTTDQDLIKLCQPYGKIVSTKAILDKNTNQC 100
Query: 61 LGYGFVNYVTAKDAERAINTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQK 120
GYGFV++ + A++A+ +L +Q++ K P+ NLYIS LP +M ++
Sbjct: 101 KGYGFVDFDSPAAAQKAVASLKANGVQAQMAKQQEQDPT-------NLYISNLPISMDEQ 153
Query: 121 DVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNG---HKPPG--- 174
++E+M FG +I++R+L D G+SRGV F R + + E I FNG PPG
Sbjct: 154 ELENMLKPFGHVISTRILRD-ANGVSRGVGFARMESTEKCEVVIQHFNGKYLKTPPGIPA 212
Query: 175 SSEPITVKFA 184
SEP+ KFA
Sbjct: 213 PSEPLLCKFA 222
Score = 47.0 bits (110), Expect = 2e-05
Identities = 31/89 (34%), Positives = 43/89 (48%), Gaps = 5/89 (5%)
Query: 222 PMGVDHMSGLSGVNVPGNASSG-----WCIFIYNLGQDADEGILWQMFGPFGAVTNVKVI 276
PM S S N N SSG ++I L + L ++ P+G + + K I
Sbjct: 33 PMAPPSPSTNSSSNNSSNNSSGEQLSKTNLYIRGLPPGTTDQDLIKLCQPYGKIVSTKAI 92
Query: 277 RDFNTNKCKGFGFVTMTNYEEAAMAIASL 305
D NTN+CKG+GFV + A A+ASL
Sbjct: 93 LDKNTNQCKGYGFVDFDSPAAAQKAVASL 121
Score = 45.4 bits (106), Expect = 7e-05
Identities = 47/209 (22%), Positives = 71/209 (33%), Gaps = 60/209 (28%)
Query: 99 SSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRS 158
S E + NLYI GLP T +D+ + +G+I++++ ++D+
Sbjct: 53 SGEQLSKTNLYIRGLPPGTTDQDLIKLCQPYGKIVSTKAILDK----------------- 95
Query: 159 EAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVALLSQLYHSPARRFGGPVHHQAQRF 218
N NQ K + F P Q
Sbjct: 96 ---------------------------NTNQCKGYGFVD---------FDSPAAAQKAVA 119
Query: 219 RFSPMGVDHMSGLSGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRD 278
GV P N ++I NL DE L M PFG V + +++RD
Sbjct: 120 SLKANGVQAQMAKQQEQDPTN------LYISNLPISMDEQELENMLKPFGHVISTRILRD 173
Query: 279 FNTNKCKGFGFVTMTNYEEAAMAIASLNG 307
N +G GF M + E+ + I NG
Sbjct: 174 AN-GVSRGVGFARMESTEKCEVVIQHFNG 201
>gi|51317351 RNA binding motif, single stranded interacting protein
3 isoform 2 [Homo sapiens]
Length = 420
Score = 101 bits (252), Expect = 8e-22
Identities = 64/190 (33%), Positives = 101/190 (53%), Gaps = 15/190 (7%)
Query: 2 SNGYEDHMAEDCRGD-IGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHS 60
+N ++ + + G+ + +TNL + LP T +L L G++ S K I DK
Sbjct: 42 TNSSSNNSSNNSSGEQLSKTNLYIRGLPPGTTDQDLIKLCQPYGKIVSTKAILDKNTNQC 101
Query: 61 LGYGFVNYVTAKDAERAINTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQK 120
GYGFV++ + A++A+ +L +Q++ K P+ NLYIS LP +M ++
Sbjct: 102 KGYGFVDFDSPAAAQKAVASLKANGVQAQMAKQQEQDPT-------NLYISNLPISMDEQ 154
Query: 121 DVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNG---HKPPG--- 174
++E+M FG +I++R+L D G+SRGV F R + + E I FNG PPG
Sbjct: 155 ELENMLKPFGHVISTRILRD-ANGVSRGVGFARMESTEKCEVVIQHFNGKYLKTPPGIPA 213
Query: 175 SSEPITVKFA 184
SEP+ KFA
Sbjct: 214 PSEPLLCKFA 223
Score = 47.0 bits (110), Expect = 2e-05
Identities = 31/89 (34%), Positives = 43/89 (48%), Gaps = 5/89 (5%)
Query: 222 PMGVDHMSGLSGVNVPGNASSG-----WCIFIYNLGQDADEGILWQMFGPFGAVTNVKVI 276
PM S S N N SSG ++I L + L ++ P+G + + K I
Sbjct: 34 PMAPPSPSTNSSSNNSSNNSSGEQLSKTNLYIRGLPPGTTDQDLIKLCQPYGKIVSTKAI 93
Query: 277 RDFNTNKCKGFGFVTMTNYEEAAMAIASL 305
D NTN+CKG+GFV + A A+ASL
Sbjct: 94 LDKNTNQCKGYGFVDFDSPAAAQKAVASL 122
Score = 45.4 bits (106), Expect = 7e-05
Identities = 47/209 (22%), Positives = 71/209 (33%), Gaps = 60/209 (28%)
Query: 99 SSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRS 158
S E + NLYI GLP T +D+ + +G+I++++ ++D+
Sbjct: 54 SGEQLSKTNLYIRGLPPGTTDQDLIKLCQPYGKIVSTKAILDK----------------- 96
Query: 159 EAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVALLSQLYHSPARRFGGPVHHQAQRF 218
N NQ K + F P Q
Sbjct: 97 ---------------------------NTNQCKGYGFVD---------FDSPAAAQKAVA 120
Query: 219 RFSPMGVDHMSGLSGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRD 278
GV P N ++I NL DE L M PFG V + +++RD
Sbjct: 121 SLKANGVQAQMAKQQEQDPTN------LYISNLPISMDEQELENMLKPFGHVISTRILRD 174
Query: 279 FNTNKCKGFGFVTMTNYEEAAMAIASLNG 307
N +G GF M + E+ + I NG
Sbjct: 175 AN-GVSRGVGFARMESTEKCEVVIQHFNG 202
>gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens]
Length = 375
Score = 97.4 bits (241), Expect = 1e-20
Identities = 74/290 (25%), Positives = 131/290 (45%), Gaps = 42/290 (14%)
Query: 22 LIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINTL 81
L V L +++T+ + LFS IG +S K+I + + Y FV + +DA A+ +
Sbjct: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP--YCFVEFYEHRDAAAALAAM 68
Query: 82 NGLRLQSKTIKVSYARPSSEVIKDA----NLYISGLPRTMTQKDVEDMFSRFGRIINSRV 137
NG ++ K +KV++A S KD ++++ L +T +D++ F+ FG+I ++RV
Sbjct: 69 NGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARV 128
Query: 138 LVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVALLS 197
+ D TG S+G F+ F + +AE AI G G I +A
Sbjct: 129 VKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGG--RQIRTNWATR----------- 175
Query: 198 QLYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNASSGWCIFIYNLGQDADE 257
PA + + ++ RF + V ++ ++ + +
Sbjct: 176 ---KPPAPK--STQENNTKQLRFEDV------------VNQSSPKNCTVYCGGIASGLTD 218
Query: 258 GILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNG 307
++ Q F PFG + ++V + KG+ FV + +E AA AI S+NG
Sbjct: 219 QLMRQTFSPFGQIMEIRVFPE------KGYSFVRFSTHESAAHAIVSVNG 262
Score = 75.1 bits (183), Expect = 8e-14
Identities = 67/258 (25%), Positives = 115/258 (44%), Gaps = 48/258 (18%)
Query: 21 NLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINT 80
++ V L +T ++++S F+ G++ A++++D G S GYGFV++ DAE AI
Sbjct: 98 HVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVH 157
Query: 81 LNGLRLQSKTIKVSYA-----RPSS------------EVI-----KDANLYISGLPRTMT 118
+ G L + I+ ++A P S +V+ K+ +Y G+ +T
Sbjct: 158 MGGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLT 217
Query: 119 QKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEP 178
+ + FS FG+I+ RV + +G +F+RF A AI S NG G
Sbjct: 218 DQLMRQTFSPFGQIMEIRVFPE------KGYSFVRFSTHESAAHAIVSVNGTTIEGH--- 268
Query: 179 ITVKF---AANPNQNKNVALL--------SQLYHSPARRFGGPVHHQAQRFRFSPMGV-D 226
VK +P+ KN + SQ+Y +P +++G + A ++ P GV
Sbjct: 269 -VVKCYWGKESPDMTKNFQQVDYSQWGQWSQVYGNP-QQYG---QYMANGWQVPPYGVYG 323
Query: 227 HMSGLSGVNVPGNASSGW 244
G V + S+ W
Sbjct: 324 QPWNQQGFGVDQSPSAAW 341
Score = 63.2 bits (152), Expect = 3e-10
Identities = 46/216 (21%), Positives = 90/216 (41%), Gaps = 50/216 (23%)
Query: 108 LYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSF 167
LY+ L R +T+ + +FS+ G + +++ + T+ + F+ F + +A A+ +
Sbjct: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTS--NDPYCFVEFYEHRDAAAALAAM 68
Query: 168 NGHKPPGSSEPITVKFAANPNQNKNVALLSQLYHSPARRFGGPVHHQAQRFRFSPMGVDH 227
NG K G + V +A P+ K
Sbjct: 69 NGRKILGKE--VKVNWATTPSSQKK----------------------------------- 91
Query: 228 MSGLSGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGF 287
+ S+ + +F+ +L + + F PFG +++ +V++D T K KG+
Sbjct: 92 -----------DTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGY 140
Query: 288 GFVTMTNYEEAAMAIASLNGYRLGDKILQVSFKTNK 323
GFV+ N +A AI + G LG + ++ ++ T K
Sbjct: 141 GFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRK 176
>gi|188219593 TIA1 protein isoform 1 [Homo sapiens]
Length = 375
Score = 97.1 bits (240), Expect = 2e-20
Identities = 81/291 (27%), Positives = 134/291 (46%), Gaps = 44/291 (15%)
Query: 22 LIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINTL 81
L V L +++T+ + LFS IG ++ K+I D AG+ Y FV + + A A+ +
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD-TAGND-PYCFVEFHEHRHAAAALAAM 66
Query: 82 NGLRLQSKTIKVSYARPSSEVIKDA----NLYISGLPRTMTQKDVEDMFSRFGRIINSRV 137
NG ++ K +KV++A S KD ++++ L +T +D++ F+ FGRI ++RV
Sbjct: 67 NGRKIMGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDARV 126
Query: 138 LVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAA-NPNQNKNVALL 196
+ D TG S+G F+ F + +AE AI G G I +A P K+
Sbjct: 127 VKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGG--RQIRTNWATRKPPAPKST--- 181
Query: 197 SQLYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNASSGWCIFIYNLGQDAD 256
Y S ++ + D + S P N + ++ +
Sbjct: 182 ---YESNTKQ----------------LSYDEVVNQSS---PSNCT----VYCGGVTSGLT 215
Query: 257 EGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNG 307
E ++ Q F PFG + ++V D KG+ FV ++E AA AI S+NG
Sbjct: 216 EQLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSVNG 260
Score = 76.3 bits (186), Expect = 4e-14
Identities = 48/171 (28%), Positives = 84/171 (49%), Gaps = 28/171 (16%)
Query: 21 NLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINT 80
++ V L +T +++++ F+ G + A++++D G S GYGFV++ DAE AI
Sbjct: 96 HVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQ 155
Query: 81 LNGLRLQSKTIKVSYA-----RPSS------------EVIKDAN-----LYISGLPRTMT 118
+ G L + I+ ++A P S EV+ ++ +Y G+ +T
Sbjct: 156 MGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLT 215
Query: 119 QKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNG 169
++ + FS FG+I+ RV D +G +F+RF+ A AI S NG
Sbjct: 216 EQLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSVNG 260
Score = 65.5 bits (158), Expect = 6e-11
Identities = 48/216 (22%), Positives = 89/216 (41%), Gaps = 50/216 (23%)
Query: 108 LYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSF 167
LY+ L R +T+ + +FS+ G N ++++D T + F+ F + A A+ +
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAAM 66
Query: 168 NGHKPPGSSEPITVKFAANPNQNKNVALLSQLYHSPARRFGGPVHHQAQRFRFSPMGVDH 227
NG K G + V +A P+ K
Sbjct: 67 NGRKIMGKE--VKVNWATTPSSQKK----------------------------------- 89
Query: 228 MSGLSGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGF 287
+ S+ + +F+ +L + + F PFG +++ +V++D T K KG+
Sbjct: 90 -----------DTSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGY 138
Query: 288 GFVTMTNYEEAAMAIASLNGYRLGDKILQVSFKTNK 323
GFV+ N +A AI + G LG + ++ ++ T K
Sbjct: 139 GFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRK 174
Score = 37.0 bits (84), Expect = 0.024
Identities = 18/73 (24%), Positives = 38/73 (52%), Gaps = 6/73 (8%)
Query: 31 MTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINTLNGLRLQSKT 90
+T+ +R FS G++ ++ DK GY FV + + + A AI ++NG ++
Sbjct: 214 LTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESAAHAIVSVNGTTIEGHV 267
Query: 91 IKVSYARPSSEVI 103
+K + + + ++I
Sbjct: 268 VKCYWGKETLDMI 280
>gi|188219591 TIA1 protein isoform 2 [Homo sapiens]
Length = 386
Score = 92.8 bits (229), Expect = 4e-19
Identities = 81/302 (26%), Positives = 134/302 (44%), Gaps = 55/302 (18%)
Query: 22 LIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINTL 81
L V L +++T+ + LFS IG ++ K+I D AG+ Y FV + + A A+ +
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD-TAGND-PYCFVEFHEHRHAAAALAAM 66
Query: 82 NGLRLQSKTIKVSYARPSSEVIKDA---------------NLYISGLPRTMTQKDVEDMF 126
NG ++ K +KV++A S KD ++++ L +T +D++ F
Sbjct: 67 NGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAF 126
Query: 127 SRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAA- 185
+ FGRI ++RV+ D TG S+G F+ F + +AE AI G G I +A
Sbjct: 127 APFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGG--RQIRTNWATR 184
Query: 186 NPNQNKNVALLSQLYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNASSGWC 245
P K+ Y S ++ + D + S P N +
Sbjct: 185 KPPAPKST------YESNTKQ----------------LSYDEVVNQSS---PSNCT---- 215
Query: 246 IFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASL 305
++ + E ++ Q F PFG + ++V D KG+ FV ++E AA AI S+
Sbjct: 216 VYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSV 269
Query: 306 NG 307
NG
Sbjct: 270 NG 271
Score = 76.3 bits (186), Expect = 4e-14
Identities = 48/171 (28%), Positives = 84/171 (49%), Gaps = 28/171 (16%)
Query: 21 NLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINT 80
++ V L +T +++++ F+ G + A++++D G S GYGFV++ DAE AI
Sbjct: 107 HVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQ 166
Query: 81 LNGLRLQSKTIKVSYA-----RPSS------------EVIKDAN-----LYISGLPRTMT 118
+ G L + I+ ++A P S EV+ ++ +Y G+ +T
Sbjct: 167 MGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLT 226
Query: 119 QKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNG 169
++ + FS FG+I+ RV D +G +F+RF+ A AI S NG
Sbjct: 227 EQLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSVNG 271
Score = 67.4 bits (163), Expect = 2e-11
Identities = 50/216 (23%), Positives = 91/216 (42%), Gaps = 39/216 (18%)
Query: 108 LYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSF 167
LY+ L R +T+ + +FS+ G N ++++D T + F+ F + A A+ +
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAAM 66
Query: 168 NGHKPPGSSEPITVKFAANPNQNKNVALLSQLYHSPARRFGGPVHHQAQRFRFSPMGVDH 227
NG K G + V +A P+ K S + + + DH
Sbjct: 67 NGRKIMGKE--VKVNWATTPSSQKKDTSSSTVVSTQRSQ-------------------DH 105
Query: 228 MSGLSGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGF 287
+F+ +L + + F PFG +++ +V++D T K KG+
Sbjct: 106 FH----------------VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGY 149
Query: 288 GFVTMTNYEEAAMAIASLNGYRLGDKILQVSFKTNK 323
GFV+ N +A AI + G LG + ++ ++ T K
Sbjct: 150 GFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRK 185
Score = 37.0 bits (84), Expect = 0.024
Identities = 18/73 (24%), Positives = 38/73 (52%), Gaps = 6/73 (8%)
Query: 31 MTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINTLNGLRLQSKT 90
+T+ +R FS G++ ++ DK GY FV + + + A AI ++NG ++
Sbjct: 225 LTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESAAHAIVSVNGTTIEGHV 278
Query: 91 IKVSYARPSSEVI 103
+K + + + ++I
Sbjct: 279 VKCYWGKETLDMI 291
>gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens]
Length = 392
Score = 92.4 bits (228), Expect = 5e-19
Identities = 76/305 (24%), Positives = 134/305 (43%), Gaps = 55/305 (18%)
Query: 22 LIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKV----AGHSLG-----------YGFV 66
L V L +++T+ + LFS IG +S K+I ++ S+G Y FV
Sbjct: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQHTSNDPYCFV 70
Query: 67 NYVTAKDAERAINTLNGLRLQSKTIKVSYARPSSEVIKDA----NLYISGLPRTMTQKDV 122
+ +DA A+ +NG ++ K +KV++A S KD ++++ L +T +D+
Sbjct: 71 EFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDI 130
Query: 123 EDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVK 182
+ F+ FG+I ++RV+ D TG S+G F+ F + +AE AI G G I
Sbjct: 131 KSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGG--RQIRTN 188
Query: 183 FAANPNQNKNVALLSQLYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNASS 242
+A PA + + ++ RF + V ++
Sbjct: 189 WATR--------------KPPAPK--STQENNTKQLRFEDV------------VNQSSPK 220
Query: 243 GWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAI 302
++ + + ++ Q F PFG + ++V + KG+ FV + +E AA AI
Sbjct: 221 NCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE------KGYSFVRFSTHESAAHAI 274
Query: 303 ASLNG 307
S+NG
Sbjct: 275 VSVNG 279
Score = 75.1 bits (183), Expect = 8e-14
Identities = 67/258 (25%), Positives = 115/258 (44%), Gaps = 48/258 (18%)
Query: 21 NLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINT 80
++ V L +T ++++S F+ G++ A++++D G S GYGFV++ DAE AI
Sbjct: 115 HVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVH 174
Query: 81 LNGLRLQSKTIKVSYA-----RPSS------------EVI-----KDANLYISGLPRTMT 118
+ G L + I+ ++A P S +V+ K+ +Y G+ +T
Sbjct: 175 MGGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLT 234
Query: 119 QKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEP 178
+ + FS FG+I+ RV + +G +F+RF A AI S NG G
Sbjct: 235 DQLMRQTFSPFGQIMEIRVFPE------KGYSFVRFSTHESAAHAIVSVNGTTIEGH--- 285
Query: 179 ITVKF---AANPNQNKNVALL--------SQLYHSPARRFGGPVHHQAQRFRFSPMGV-D 226
VK +P+ KN + SQ+Y +P +++G + A ++ P GV
Sbjct: 286 -VVKCYWGKESPDMTKNFQQVDYSQWGQWSQVYGNP-QQYG---QYMANGWQVPPYGVYG 340
Query: 227 HMSGLSGVNVPGNASSGW 244
G V + S+ W
Sbjct: 341 QPWNQQGFGVDQSPSAAW 358
Score = 57.4 bits (137), Expect = 2e-08
Identities = 48/231 (20%), Positives = 91/231 (39%), Gaps = 63/231 (27%)
Query: 108 LYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQ--------TTGLS-------RGVAFI 152
LY+ L R +T+ + +FS+ G + +++ +Q + G S F+
Sbjct: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQHTSNDPYCFV 70
Query: 153 RFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVALLSQLYHSPARRFGGPVH 212
F + +A A+ + NG K G + V +A P+ K
Sbjct: 71 EFYEHRDAAAALAAMNGRKILGKE--VKVNWATTPSSQKK-------------------- 108
Query: 213 HQAQRFRFSPMGVDHMSGLSGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTN 272
+ S+ + +F+ +L + + F PFG +++
Sbjct: 109 --------------------------DTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISD 142
Query: 273 VKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYRLGDKILQVSFKTNK 323
+V++D T K KG+GFV+ N +A AI + G LG + ++ ++ T K
Sbjct: 143 ARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRK 193
>gi|109948285 poly(A) binding protein, cytoplasmic 1-like 2B [Homo
sapiens]
Length = 200
Score = 86.7 bits (213), Expect = 3e-17
Identities = 50/151 (33%), Positives = 83/151 (54%), Gaps = 4/151 (2%)
Query: 21 NLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINT 80
+L V L +T+ L FS G + S ++ RDK+ SLGY +VNY DA+RA+ T
Sbjct: 3 SLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALET 62
Query: 81 LNGLRLQSKTIKVSYAR--PSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVL 138
LN ++ + +++ +++ PS N++I L +T+ K + ++FS FG I++ +V
Sbjct: 63 LNFDVIKGRPVRIMWSQRDPSLRKSGVGNVFIKNLGKTIDNKALYNIFSAFGNILSCKVA 122
Query: 139 VDQTTGLSRGVAFIRFDKRSEAEEAITSFNG 169
D+ +G F+ F K+ AE AI NG
Sbjct: 123 CDEKG--PKGYGFVHFQKQESAERAIDVMNG 151
Score = 53.1 bits (126), Expect = 3e-07
Identities = 57/223 (25%), Positives = 92/223 (41%), Gaps = 55/223 (24%)
Query: 106 ANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAIT 165
A+LY+ L +T+ + + FS G I++ R+ D+ T S G A++ + + +A+ A+
Sbjct: 2 ASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALE 61
Query: 166 SFNGHKPPGSSEPITVKFAA-NPNQNKNVALLSQLYHSPARRFGGPVHHQAQRFRFSPMG 224
+ N G P+ + ++ +P+ K
Sbjct: 62 TLNFDVIKG--RPVRIMWSQRDPSLRK--------------------------------- 86
Query: 225 VDHMSGLSGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKC 284
SGV GN +FI NLG+ D L+ +F FG + + KV D
Sbjct: 87 -------SGV---GN------VFIKNLGKTIDNKALYNIFSAFGNILSCKVACD--EKGP 128
Query: 285 KGFGFVTMTNYEEAAMAIASLNGYRLG-DKILQVSFKTNKSHK 326
KG+GFV E A AI +NG L KI FK++K +
Sbjct: 129 KGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSHKERE 171
Score = 45.1 bits (105), Expect = 9e-05
Identities = 31/107 (28%), Positives = 52/107 (48%), Gaps = 6/107 (5%)
Query: 18 GRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERA 77
G N+ + L + + L ++FS+ G + S K+ D+ GYGFV++ + AERA
Sbjct: 88 GVGNVFIKNLGKTIDNKALYNIFSAFGNILSCKVACDEKGPK--GYGFVHFQKQESAERA 145
Query: 78 INTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVED 124
I+ +NG+ L + I V + E + + R T DV+D
Sbjct: 146 IDVMNGMFLNYRKIFVGRFKSHKEREAERGAW----ARQSTSADVKD 188
>gi|61175237 poly(A) binding protein, cytoplasmic 1-like 2A [Homo
sapiens]
Length = 200
Score = 86.7 bits (213), Expect = 3e-17
Identities = 50/151 (33%), Positives = 83/151 (54%), Gaps = 4/151 (2%)
Query: 21 NLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINT 80
+L V L +T+ L FS G + S ++ RDK+ SLGY +VNY DA+RA+ T
Sbjct: 3 SLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALET 62
Query: 81 LNGLRLQSKTIKVSYAR--PSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVL 138
LN ++ + +++ +++ PS N++I L +T+ K + ++FS FG I++ +V
Sbjct: 63 LNFDVIKGRPVRIMWSQRDPSLRKSGVGNVFIKNLGKTIDNKALYNIFSAFGNILSCKVA 122
Query: 139 VDQTTGLSRGVAFIRFDKRSEAEEAITSFNG 169
D+ +G F+ F K+ AE AI NG
Sbjct: 123 CDEKG--PKGYGFVHFQKQESAERAIDVMNG 151
Score = 53.1 bits (126), Expect = 3e-07
Identities = 57/223 (25%), Positives = 92/223 (41%), Gaps = 55/223 (24%)
Query: 106 ANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAIT 165
A+LY+ L +T+ + + FS G I++ R+ D+ T S G A++ + + +A+ A+
Sbjct: 2 ASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALE 61
Query: 166 SFNGHKPPGSSEPITVKFAA-NPNQNKNVALLSQLYHSPARRFGGPVHHQAQRFRFSPMG 224
+ N G P+ + ++ +P+ K
Sbjct: 62 TLNFDVIKG--RPVRIMWSQRDPSLRK--------------------------------- 86
Query: 225 VDHMSGLSGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKC 284
SGV GN +FI NLG+ D L+ +F FG + + KV D
Sbjct: 87 -------SGV---GN------VFIKNLGKTIDNKALYNIFSAFGNILSCKVACD--EKGP 128
Query: 285 KGFGFVTMTNYEEAAMAIASLNGYRLG-DKILQVSFKTNKSHK 326
KG+GFV E A AI +NG L KI FK++K +
Sbjct: 129 KGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSHKERE 171
Score = 45.1 bits (105), Expect = 9e-05
Identities = 31/107 (28%), Positives = 52/107 (48%), Gaps = 6/107 (5%)
Query: 18 GRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERA 77
G N+ + L + + L ++FS+ G + S K+ D+ GYGFV++ + AERA
Sbjct: 88 GVGNVFIKNLGKTIDNKALYNIFSAFGNILSCKVACDEKGPK--GYGFVHFQKQESAERA 145
Query: 78 INTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVED 124
I+ +NG+ L + I V + E + + R T DV+D
Sbjct: 146 IDVMNGMFLNYRKIFVGRFKSHKEREAERGAW----ARQSTSADVKD 188
>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
Length = 424
Score = 86.3 bits (212), Expect = 3e-17
Identities = 54/163 (33%), Positives = 91/163 (55%), Gaps = 4/163 (2%)
Query: 24 VNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINTLNG 83
V L + +++ L LF G V + + +D+V G GYGFV +++ +DA+ AI +N
Sbjct: 17 VGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIMNM 76
Query: 84 LRLQSKTIKVSYARPSSEVIK-DANLYISGLPRTMTQKDVEDMFSRFGRIINS-RVLVDQ 141
++L K I+V+ A ++ + AN++I L + +K + D FS FG I+ + +++ D
Sbjct: 77 IKLYGKPIRVNKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDP 136
Query: 142 TTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFA 184
TG S+G AFI F ++ AI + NG + PITV +A
Sbjct: 137 DTGNSKGYAFINFASFDASDAAIEAMNGQYL--CNRPITVSYA 177
Score = 77.8 bits (190), Expect = 1e-14
Identities = 60/232 (25%), Positives = 102/232 (43%), Gaps = 52/232 (22%)
Query: 96 ARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFD 155
A P SE +DA +Y+ GL +++ + ++F + G ++N+ + D+ TG +G F+ F
Sbjct: 3 AGPISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFL 62
Query: 156 KRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVALLSQLYHSPARRFGGPVHHQA 215
+A+ AI N K G +PI V A+ N+N +V
Sbjct: 63 SEEDADYAIKIMNMIKLYG--KPIRVNKASAHNKNLDV---------------------- 98
Query: 216 QRFRFSPMGVDHMSGLSGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNV-K 274
G N IFI NL + DE +L+ F FG + K
Sbjct: 99 -----------------GAN----------IFIGNLDPEIDEKLLYDTFSAFGVILQTPK 131
Query: 275 VIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYRLGDKILQVSFKTNKSHK 326
++RD +T KG+ F+ +++ + AI ++NG L ++ + VS+ K K
Sbjct: 132 IMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKKDSK 183
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,443,278
Number of Sequences: 37866
Number of extensions: 492645
Number of successful extensions: 2501
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 220
Number of HSP's successfully gapped in prelim test: 95
Number of HSP's that attempted gapping in prelim test: 1164
Number of HSP's gapped (non-prelim): 1023
length of query: 326
length of database: 18,247,518
effective HSP length: 103
effective length of query: 223
effective length of database: 14,347,320
effective search space: 3199452360
effective search space used: 3199452360
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.