Guide to the Human Genome
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Search of human proteins with 38146113

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo
sapiens]
         (375 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s...   730   0.0  
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s...   713   0.0  
gi|38146109 arginine/serine-rich coiled-coil 2 isoform c [Homo s...   392   e-109
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi...   112   7e-25
gi|55741709 RNA binding motif protein 25 [Homo sapiens]               111   9e-25
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]           107   2e-23
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ...   106   3e-23
gi|52426743 cisplatin resistance-associated overexpressed protei...   103   3e-22
gi|19923485 cisplatin resistance-associated overexpressed protei...   103   3e-22
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ...   102   6e-22
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [...   102   6e-22
gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]     100   2e-21
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ...   100   3e-21
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]            99   8e-21
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]        98   1e-20
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]     97   2e-20
gi|116812577 LUC7-like 2 [Homo sapiens]                                96   7e-20
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        95   9e-20
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]     93   3e-19
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]           93   4e-19
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]           93   4e-19
gi|38488727 arginine/serine-rich coiled-coil 1 [Homo sapiens]          92   6e-19
gi|42560244 peptidylprolyl isomerase G [Homo sapiens]                  92   6e-19
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti...    92   8e-19
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]           92   8e-19
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]            91   2e-18
gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]           90   3e-18
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]          90   4e-18
gi|41393554 LUC7-like isoform b [Homo sapiens]                         89   8e-18
gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]            88   1e-17

>gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo
           sapiens]
          Length = 375

 Score =  730 bits (1884), Expect = 0.0
 Identities = 375/375 (100%), Positives = 375/375 (100%)

Query: 1   MIRTNFFLKQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKS 60
           MIRTNFFLKQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKS
Sbjct: 1   MIRTNFFLKQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKS 60

Query: 61  SRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSR 120
           SRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSR
Sbjct: 61  SRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSR 120

Query: 121 SRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEAL 180
           SRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEAL
Sbjct: 121 SRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEAL 180

Query: 181 ARRLERAKKLQEQREKEMVEKQKQQEIAAAAATGGSVLNVAALLASGTQVTPQIAMAAQM 240
           ARRLERAKKLQEQREKEMVEKQKQQEIAAAAATGGSVLNVAALLASGTQVTPQIAMAAQM
Sbjct: 181 ARRLERAKKLQEQREKEMVEKQKQQEIAAAAATGGSVLNVAALLASGTQVTPQIAMAAQM 240

Query: 241 AALQAKALAETGIAVPSYYNPAAVNPMKFAEQEKKRKMLWQGKKEGDKSQSAEIWEKLNF 300
           AALQAKALAETGIAVPSYYNPAAVNPMKFAEQEKKRKMLWQGKKEGDKSQSAEIWEKLNF
Sbjct: 241 AALQAKALAETGIAVPSYYNPAAVNPMKFAEQEKKRKMLWQGKKEGDKSQSAEIWEKLNF 300

Query: 301 GNKDQNVKFRKLMGIKSEDEAGCSSVDEESYKTLKQQEEVFRNLDAQYEMARSQTHTQRG 360
           GNKDQNVKFRKLMGIKSEDEAGCSSVDEESYKTLKQQEEVFRNLDAQYEMARSQTHTQRG
Sbjct: 301 GNKDQNVKFRKLMGIKSEDEAGCSSVDEESYKTLKQQEEVFRNLDAQYEMARSQTHTQRG 360

Query: 361 MGLGFTSSMRGMDAV 375
           MGLGFTSSMRGMDAV
Sbjct: 361 MGLGFTSSMRGMDAV 375


>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
           sapiens]
          Length = 434

 Score =  713 bits (1840), Expect = 0.0
 Identities = 366/367 (99%), Positives = 367/367 (100%)

Query: 9   KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 68
           K+GRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR
Sbjct: 68  KEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 127

Query: 69  SRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHR 128
           SRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHR
Sbjct: 128 SRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHR 187

Query: 129 HRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAK 188
           HRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAK
Sbjct: 188 HRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAK 247

Query: 189 KLQEQREKEMVEKQKQQEIAAAAATGGSVLNVAALLASGTQVTPQIAMAAQMAALQAKAL 248
           KLQEQREKEMVEKQKQQEIAAAAATGGSVLNVAALLASGTQVTPQIAMAAQMAALQAKAL
Sbjct: 248 KLQEQREKEMVEKQKQQEIAAAAATGGSVLNVAALLASGTQVTPQIAMAAQMAALQAKAL 307

Query: 249 AETGIAVPSYYNPAAVNPMKFAEQEKKRKMLWQGKKEGDKSQSAEIWEKLNFGNKDQNVK 308
           AETGIAVPSYYNPAAVNPMKFAEQEKKRKMLWQGKKEGDKSQSAEIWEKLNFGNKDQNVK
Sbjct: 308 AETGIAVPSYYNPAAVNPMKFAEQEKKRKMLWQGKKEGDKSQSAEIWEKLNFGNKDQNVK 367

Query: 309 FRKLMGIKSEDEAGCSSVDEESYKTLKQQEEVFRNLDAQYEMARSQTHTQRGMGLGFTSS 368
           FRKLMGIKSEDEAGCSSVDEESYKTLKQQEEVFRNLDAQYEMARSQTHTQRGMGLGFTSS
Sbjct: 368 FRKLMGIKSEDEAGCSSVDEESYKTLKQQEEVFRNLDAQYEMARSQTHTQRGMGLGFTSS 427

Query: 369 MRGMDAV 375
           MRGMDAV
Sbjct: 428 MRGMDAV 434


>gi|38146109 arginine/serine-rich coiled-coil 2 isoform c [Homo
           sapiens]
          Length = 202

 Score =  392 bits (1007), Expect = e-109
 Identities = 202/202 (100%), Positives = 202/202 (100%)

Query: 174 MDAQEALARRLERAKKLQEQREKEMVEKQKQQEIAAAAATGGSVLNVAALLASGTQVTPQ 233
           MDAQEALARRLERAKKLQEQREKEMVEKQKQQEIAAAAATGGSVLNVAALLASGTQVTPQ
Sbjct: 1   MDAQEALARRLERAKKLQEQREKEMVEKQKQQEIAAAAATGGSVLNVAALLASGTQVTPQ 60

Query: 234 IAMAAQMAALQAKALAETGIAVPSYYNPAAVNPMKFAEQEKKRKMLWQGKKEGDKSQSAE 293
           IAMAAQMAALQAKALAETGIAVPSYYNPAAVNPMKFAEQEKKRKMLWQGKKEGDKSQSAE
Sbjct: 61  IAMAAQMAALQAKALAETGIAVPSYYNPAAVNPMKFAEQEKKRKMLWQGKKEGDKSQSAE 120

Query: 294 IWEKLNFGNKDQNVKFRKLMGIKSEDEAGCSSVDEESYKTLKQQEEVFRNLDAQYEMARS 353
           IWEKLNFGNKDQNVKFRKLMGIKSEDEAGCSSVDEESYKTLKQQEEVFRNLDAQYEMARS
Sbjct: 121 IWEKLNFGNKDQNVKFRKLMGIKSEDEAGCSSVDEESYKTLKQQEEVFRNLDAQYEMARS 180

Query: 354 QTHTQRGMGLGFTSSMRGMDAV 375
           QTHTQRGMGLGFTSSMRGMDAV
Sbjct: 181 QTHTQRGMGLGFTSSMRGMDAV 202


>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
           sapiens]
          Length = 1031

 Score =  112 bits (279), Expect = 7e-25
 Identities = 75/172 (43%), Positives = 104/172 (60%), Gaps = 16/172 (9%)

Query: 50  EDRHKRKERKSSRGRSHSRSRSRERRH-RSRSRERKKSRSRSRERKKSRSRSRERKKSRS 108
           E RH RK R +SRGRS SRSRSR     RS+  + ++SRSR R+R++ RSRSR++++SRS
Sbjct: 4   ESRHYRK-RSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRS 62

Query: 109 RSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKR---------IEKPRRFSRSLS 159
           R R+R RR RSR R RSR R R+RSR R RSRSR R +R          +K    SRS  
Sbjct: 63  RDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKE 122

Query: 160 RT----PSPPPFRGRNTAMDAQEALARRLERAKKLQEQRE-KEMVEKQKQQE 206
           +T     S    + ++   D +E  A   ++ K  +E R+ KE VEK ++++
Sbjct: 123 KTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQ 174



 Score = 96.3 bits (238), Expect = 4e-20
 Identities = 65/189 (34%), Positives = 102/189 (53%), Gaps = 18/189 (9%)

Query: 12  RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRS 71
           +R  S+ +S  + +S   +DK   S +G +R + S    DR +R+ER  SR +  SRSR 
Sbjct: 10  KRSASRGRSGSRSRSRSPSDKR--SKRGDDRRSRSR---DRDRRRERSRSRDKRRSRSRD 64

Query: 72  RERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRT 131
           R+R  RSRSRE    R RSRER+  RSRSR+R++SRSRSR R+ R  S      +  +R+
Sbjct: 65  RKRLRRSRSRE----RDRSRERR--RSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRS 118

Query: 132 RSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQ 191
           RS+ +T      ++K+ +K         +        G       +E + +R ER +K +
Sbjct: 119 RSKEKTDGGESSKEKKKDKD-------DKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWR 171

Query: 192 EQREKEMVE 200
           E++ K+ +E
Sbjct: 172 EEQRKKAME 180



 Score = 82.4 bits (202), Expect = 6e-16
 Identities = 55/136 (40%), Positives = 76/136 (55%), Gaps = 3/136 (2%)

Query: 72  RERRH-RSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHR 130
           RE RH R RS  R +S SRSR R  S  RS+     RSRSR+R RR R RSRSR + R R
Sbjct: 3   RESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRR-RERSRSRDKRRSR 61

Query: 131 TRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKL 190
           +R R R R RSR R++   + RR SRS  R  S    RGR +   +    +++ E   + 
Sbjct: 62  SRDRKRLR-RSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRS 120

Query: 191 QEQREKEMVEKQKQQE 206
           +E+ +     K+K+++
Sbjct: 121 KEKTDGGESSKEKKKD 136



 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 52/162 (32%), Positives = 81/162 (50%), Gaps = 17/162 (10%)

Query: 9   KQGRRHESKDKSSKKHK-SEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHS 67
           + G R  S+  S K+ K  ++   +    D+ RER  S +    R  R  ++  R RS  
Sbjct: 17  RSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSR-SRDRKRLRRSRSRE 75

Query: 68  RSRSRERRHRSRSRERKKSRSRSRERK-------------KSRSRSRERKKSRSRSRERK 114
           R RSRERR RSRSR+R++SRSRSR R+             ++RSRS+E+      S+E+K
Sbjct: 76  RDRSRERR-RSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKK 134

Query: 115 RRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSR 156
           +    +   + +       +++     R RK+R+EK R   R
Sbjct: 135 KDKDDKEDEKEKDAGNF-DQNKLEEEMRKRKERVEKWREEQR 175



 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 35/156 (22%), Positives = 66/156 (42%), Gaps = 23/156 (14%)

Query: 12  RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGR------- 64
           RR  S+ +  ++ +S +      S  + R+R         R +R+ R  SRGR       
Sbjct: 48  RRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSP 107

Query: 65  ------SHSRSRSRERRHRSR-SRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRI 117
                 + +RSRS+E+      S+E+KK +    + K+  + + ++ K     R+RK R+
Sbjct: 108 GNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERV 167

Query: 118 RSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRR 153
                     + R   R +      + KK IE+ ++
Sbjct: 168 ---------EKWREEQRKKAMENIGELKKEIEEMKQ 194



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 25/100 (25%), Positives = 44/100 (44%), Gaps = 4/100 (4%)

Query: 10  QGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKS---SRGRSH 66
           +GRR  S    +K  K+E  +  +  +D G       ++ +D+   KE+ +    + +  
Sbjct: 98  RGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLE 157

Query: 67  SRSRSR-ERRHRSRSRERKKSRSRSRERKKSRSRSRERKK 105
              R R ER  + R  +RKK+     E KK     ++ KK
Sbjct: 158 EEMRKRKERVEKWREEQRKKAMENIGELKKEIEEMKQGKK 197


>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
          Length = 843

 Score =  111 bits (278), Expect = 9e-25
 Identities = 69/201 (34%), Positives = 105/201 (52%), Gaps = 11/201 (5%)

Query: 13  RHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSR 72
           + E + +  +K + E   ++E   ++ RER    E   +R K KER+  R R   R R++
Sbjct: 297 KKEKERQEIEKERRERERERERERER-REREREREREREREKEKERERERERDRDRDRTK 355

Query: 73  ER-RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKR-RIRSRSRSRSRHRHR 130
           ER R R R R+R + R RS +R K RSRSRE+ + R R RER+R R R R R R R R R
Sbjct: 356 ERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERER 415

Query: 131 TRSRSRTRSRSRDRKKRIEKP-------RRFSRSLSRTPSPPPFRGRNTAMDAQEALARR 183
            R R R R R +D+K+  E+        R+  R L    +    R +N  +  +    R 
Sbjct: 416 EREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEI-RERKKTRE 474

Query: 184 LERAKKLQEQREKEMVEKQKQ 204
            E+  + +E+R +EM ++ K+
Sbjct: 475 YEKEAEREEERRREMAKEAKR 495



 Score = 99.4 bits (246), Expect = 5e-21
 Identities = 51/169 (30%), Positives = 92/169 (54%), Gaps = 1/169 (0%)

Query: 41  ERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRS 100
           ++L   +  +++ +++  K  R R   R R RERR R R RER++ R + +ER++ R R 
Sbjct: 289 KKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERD 348

Query: 101 RERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSR 160
           R+R +++ R R+R R  R R R R R   R + RSR+R +SRDR++  E+ R   R   R
Sbjct: 349 RDRDRTKERDRDRDRE-RDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERER 407

Query: 161 TPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQEIAA 209
                  R R    + +    ++ +R +  ++  E+  +E++ +++ AA
Sbjct: 408 EREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAA 456



 Score = 97.1 bits (240), Expect = 2e-20
 Identities = 62/180 (34%), Positives = 88/180 (48%), Gaps = 6/180 (3%)

Query: 27  EEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKS 86
           E+ N  E   DK            D HK+ E +  +     +   +ERR R R RER++ 
Sbjct: 262 EDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERE 321

Query: 87  RSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKK 146
           R R RER++ R R RE++K R R RER R  R R++ R R R R R R R R RS DR K
Sbjct: 322 R-REREREREREREREKEKERERERERDRD-RDRTKERDRDRDRERDRDRDRERSSDRNK 379

Query: 147 RIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQE 206
              + R  SR   R       R R    + +    R  ER ++ + +RE+E  +K+ ++E
Sbjct: 380 DRSRSREKSRDRERERE----REREREREREREREREREREREREREREREKDKKRDREE 435



 Score = 97.1 bits (240), Expect = 2e-20
 Identities = 70/197 (35%), Positives = 99/197 (50%), Gaps = 11/197 (5%)

Query: 13  RHESKDKSSKKHKSEEHNDKEHSSDK-GRERLNSSENGEDRHKRKERKSSRGRSHSRSRS 71
           R  SK + + K   EE   KE    +  +ER       E   +R+ER+  R R   R + 
Sbjct: 279 REISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKE 338

Query: 72  RERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRT 131
           +ER  R R R+R + R++ R+R + R R R+R + RS  R  K R RSR +SR R R R 
Sbjct: 339 KERE-RERERDRDRDRTKERDRDRDRERDRDRDRERSSDR-NKDRSRSREKSRDRERERE 396

Query: 132 RSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARR-LERAKKL 190
           R R R R R R+R++  E+ R   R   R       + R+   D ++A  RR LER  KL
Sbjct: 397 REREREREREREREREREREREREREREREKD----KKRDREEDEEDAYERRKLER--KL 450

Query: 191 QEQREKEMVEKQKQQEI 207
           +E +E    E+ K  EI
Sbjct: 451 RE-KEAAYQERLKNWEI 466



 Score = 75.5 bits (184), Expect = 7e-14
 Identities = 55/204 (26%), Positives = 99/204 (48%), Gaps = 20/204 (9%)

Query: 13  RHESKDKSSKKHKSEEHN-DKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRS 71
           R   +D+   + +S + N D+  S +K R+R    E   +R + +ER+  R R   R R 
Sbjct: 361 RDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERE 420

Query: 72  RER-RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHR 130
           RER R + + R+R++    + ER+K   + RE K++  + R +   IR R ++R   +  
Sbjct: 421 REREREKDKKRDREEDEEDAYERRKLERKLRE-KEAAYQERLKNWEIRERKKTREYEKEA 479

Query: 131 TRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRL-ERAKK 189
            R   R R  +++ K+  E    +         P  +RG         AL +RL +R K+
Sbjct: 480 EREEERRREMAKEAKRLKEFLEDYD---DDRDDPKYYRG--------SALQKRLRDREKE 528

Query: 190 LQ-----EQREKEMVEKQKQQEIA 208
           ++      +REKE +E+ +Q+ +A
Sbjct: 529 MEADERDRKREKEELEEIRQRLLA 552



 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 55/221 (24%), Positives = 89/221 (40%), Gaps = 33/221 (14%)

Query: 16  SKDKSSKKHKS---EEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSR 72
           +KD+S  + KS   E   ++E   ++ RER    E   +R + +ER+  + +   R    
Sbjct: 378 NKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDE 437

Query: 73  ERRHRSRSRERKKSRSRS-----------RERKKSRSRSRERKKSRSRSRERKRRIR--- 118
           E  +  R  ERK     +           RERKK+R   +E ++   R RE  +  +   
Sbjct: 438 EDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLK 497

Query: 119 ------SRSRSRSRHRHRTRSRSRTRSR-------SRDRKKRIEKPRRFSRSLSRTPSPP 165
                    R   ++   +  + R R R        RDRK+  E+     + L     P 
Sbjct: 498 EFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPD 557

Query: 166 PFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQE 206
           P          QEA  RR  + K+  E  E+E  EKQ+++E
Sbjct: 558 P--DAELQRMEQEAERRRQPQIKQEPESEEEE-EEKQEKEE 595



 Score = 33.9 bits (76), Expect = 0.24
 Identities = 32/165 (19%), Positives = 65/165 (39%), Gaps = 11/165 (6%)

Query: 19  KSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHK-RKERKSSRGRS-HSRSRSRERRH 76
           K +++++ E   ++E   +  +E     E  ED    R + K  RG +   R R RE+  
Sbjct: 470 KKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEM 529

Query: 77  RSRSRERKKSRSRSRE-RKKSRSRSRE------RKKSRSRSRERKRRIRSRSRSRSRHRH 129
            +  R+RK+ +    E R++  +          ++  +   R R+ +I+    S      
Sbjct: 530 EADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEE 589

Query: 130 RTRSRSRTRSRSRDRKKRIEKP--RRFSRSLSRTPSPPPFRGRNT 172
           +     +      + ++  +KP  +   R +S  PS     G  T
Sbjct: 590 KQEKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSASGNAT 634


>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 202

 Score =  107 bits (266), Expect = 2e-23
 Identities = 65/193 (33%), Positives = 105/193 (54%), Gaps = 20/193 (10%)

Query: 22  KKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRER------- 74
           +K +++   + E   D+ RER N +E  E+RH++++R   R R   R + RER       
Sbjct: 7   RKRETDRGKETERERDRQRERENQTER-ENRHRQRDRHRERDRQTDREKERERQKERDRQ 65

Query: 75  RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRI-RSRSRSRSRHRHRTRS 133
           R R R  ER+  R R R+R++ R R  +R++ + R RERKR   R+R R+R   R R + 
Sbjct: 66  RQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQ 125

Query: 134 RSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQ 193
             R R R R+R+++ E+ R+  R           R R T  + Q   A R ER K+ +++
Sbjct: 126 TERERDRERERQRQRERERQRQRE----------RKRETDRERQR-WAEREERKKERKKE 174

Query: 194 REKEMVEKQKQQE 206
           R+KE  EK+K+++
Sbjct: 175 RKKERKEKKKEEK 187



 Score = 89.7 bits (221), Expect = 4e-18
 Identities = 51/152 (33%), Positives = 78/152 (51%), Gaps = 8/152 (5%)

Query: 9   KQGRRHESKDKSSKKHKSEEHN-DKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHS 67
           +Q  RH  +D+ + + K  E   +++    + RE    +E   +R +++ERK    R   
Sbjct: 38  RQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERD 97

Query: 68  RSRSRER-RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKR-RIRSRSRSRS 125
           + R RER R   R+RER +   R R+++  R R RER++ R R RER+R R R R   R 
Sbjct: 98  KDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRE 157

Query: 126 RHR-----HRTRSRSRTRSRSRDRKKRIEKPR 152
           R R      R + R + R + R  KK+ EK R
Sbjct: 158 RQRWAEREERKKERKKERKKERKEKKKEEKRR 189



 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 34/117 (29%), Positives = 58/117 (49%), Gaps = 12/117 (10%)

Query: 89  RSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRI 148
           R RERK+   R +E ++ R R RER+ +    +R R R RHR R R   R + R+R+K  
Sbjct: 3   RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKER 62

Query: 149 EKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQ 205
           ++ R+  R   R              + Q    R+ ER ++   +R+K+   ++K++
Sbjct: 63  DRQRQRERETER------------ETERQRERQRQRERKRQTDRERDKDRDRERKRE 107


>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
           sapiens]
          Length = 600

 Score =  106 bits (265), Expect = 3e-23
 Identities = 57/195 (29%), Positives = 99/195 (50%), Gaps = 15/195 (7%)

Query: 12  RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRS 71
           R  E++ ++ +K +++   D++  +++ RE+        +R +  ER++ R +   R R 
Sbjct: 214 RERETETETERKRQTDRERDRQRKTEREREKQ------AERERASERETERDKERERERD 267

Query: 72  RERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRT 131
           R+R    R +ER++   R R+R+  R R  ERK+ R R RER+R    R+R R R R R 
Sbjct: 268 RDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERE---RNRKRERERERE 324

Query: 132 RSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQ 191
           R R R R   RDR+K  E+ R+    + R       R R T  + +    R  ER ++  
Sbjct: 325 RERERQRETERDREKERERKRKRQTEMDRE------RNRQTGREGRRQAERERERERERD 378

Query: 192 EQREKEMVEKQKQQE 206
            Q  +E  E+++ ++
Sbjct: 379 RQSAREREERERDRD 393



 Score =  101 bits (251), Expect = 1e-21
 Identities = 52/198 (26%), Positives = 97/198 (48%), Gaps = 1/198 (0%)

Query: 9   KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 68
           +Q  R+  K++  +K++ E    +     + +     SE G +R + +E ++   R    
Sbjct: 169 RQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQT 228

Query: 69  SRSRERRHRS-RSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRH 127
            R R+R+ ++ R RE++  R R+ ER+  R + RER++ R R R+R+++ R R   R R 
Sbjct: 229 DRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQ 288

Query: 128 RHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERA 187
           R   R R   R R R R++  E+ R   R   R       R R T  D ++   R+ +R 
Sbjct: 289 RRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQ 348

Query: 188 KKLQEQREKEMVEKQKQQ 205
            ++  +R ++   + ++Q
Sbjct: 349 TEMDRERNRQTGREGRRQ 366



 Score =  100 bits (249), Expect = 2e-21
 Identities = 63/211 (29%), Positives = 103/211 (48%), Gaps = 14/211 (6%)

Query: 9   KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRH---------KRKERK 59
           ++ R+ +++ +  K+ + E  +++E   DK RER    +   DR          ++++R+
Sbjct: 231 ERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRR 290

Query: 60  SSRGRSHSRSRSRER-RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRI- 117
           + R R   R R R+R R R R R RK+ R R RER++ R R  ER + + R R+RKR+  
Sbjct: 291 TERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTE 350

Query: 118 --RSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMD 175
             R R+R   R   R   R R R R RDR+   E+  R  R   R       R      D
Sbjct: 351 MDRERNRQTGREGRRQAERERERERERDRQSAREREER-ERDRDRDRQKERERQTEKDRD 409

Query: 176 AQEALARRLERAKKLQEQREKEMVEKQKQQE 206
            Q    ++ ER K  + +R +E   ++++Q+
Sbjct: 410 GQRETEKQREREKDRESERGRERGREREKQK 440



 Score = 96.3 bits (238), Expect = 4e-20
 Identities = 56/201 (27%), Positives = 100/201 (49%), Gaps = 16/201 (7%)

Query: 13  RHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENG--EDRHKRKERKSSRGRSHSRSR 70
           RH  +D+  ++ +  E  ++E  +D+ R+R    E    ++R +  ER+  RGR      
Sbjct: 87  RHRKRDRHRERQRDRE-KERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDG 145

Query: 71  SRER---RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRH 127
            RER   R   + RER+  R R R+ +++R + RER+K+R   RER+R+    +++  RH
Sbjct: 146 QRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRH 205

Query: 128 RHRTRSRSRTR--SRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLE 185
             R R R R R      +RK++ ++ R   R   R         R    + + A  R  E
Sbjct: 206 SERGRERERERETETETERKRQTDRERDRQRKTERE--------REKQAERERASERETE 257

Query: 186 RAKKLQEQREKEMVEKQKQQE 206
           R K+ + +R+++    ++Q+E
Sbjct: 258 RDKERERERDRDRDRDRRQKE 278



 Score = 94.0 bits (232), Expect = 2e-19
 Identities = 60/215 (27%), Positives = 97/215 (45%), Gaps = 20/215 (9%)

Query: 9   KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 68
           ++GR  ++  +  ++ + +   ++E  +D+ R+R       ++R + K R+  R R   R
Sbjct: 136 ERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERE--R 193

Query: 69  SRSRERRHRSRSRERKKSRSRSRE--------RKKSRSRSRERKKSRSRSRERKR-RIRS 119
            R +E +   R  ER + R R RE        R+  R R R+RK  R R ++ +R R   
Sbjct: 194 QREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASE 253

Query: 120 RSRSRSRHRHRTRSRSRTRSR---------SRDRKKRIEKPRRFSRSLSRTPSPPPFRGR 170
           R   R + R R R R R R R          R R++R E+ R   R   R       R R
Sbjct: 254 RETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERER 313

Query: 171 NTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQ 205
           N   + +    R  ER ++ +  REKE   K+K+Q
Sbjct: 314 NRKRERERERERERERQRETERDREKERERKRKRQ 348



 Score = 93.2 bits (230), Expect = 3e-19
 Identities = 55/194 (28%), Positives = 93/194 (47%), Gaps = 5/194 (2%)

Query: 9   KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 68
           ++  R + +++   + +  +   KE      R+R   +E   +  +++ER+  R R   R
Sbjct: 254 RETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERER 313

Query: 69  SRSRER---RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERK-RRIRSRSRSR 124
           +R RER   R R R R+R+  R R +ER++ R R  E  + R+R   R+ RR   R R R
Sbjct: 314 NRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERER 373

Query: 125 SRHRHRTRSRSR-TRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARR 183
            R R R  +R R  R R RDR ++ E+ R+  +           R R    +++    R 
Sbjct: 374 ERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERG 433

Query: 184 LERAKKLQEQREKE 197
            ER K+   +R++E
Sbjct: 434 REREKQKGRERDRE 447



 Score = 92.8 bits (229), Expect = 4e-19
 Identities = 57/207 (27%), Positives = 97/207 (46%), Gaps = 10/207 (4%)

Query: 9   KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 68
           +Q  R   ++K   + +++   ++    D+ R+R    E   DR K +ER++ R R   R
Sbjct: 58  RQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQR 117

Query: 69  SRSRER---RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRS 125
            + R R   R R   RE ++ R R  + ++ R R R+ +K R R  +R+R+ R   R+R 
Sbjct: 118 EKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQ-RQTERNRQ 176

Query: 126 RHRHRTRSRSRTRSRSRDRKKRIEKPRRFS---RSLSRTPSPPPFRGRNTAMDAQEALAR 182
           + R R ++R   R R R R+K  +   R S   R   R         R    D +    R
Sbjct: 177 KEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQR 236

Query: 183 RLERAKKLQEQREK---EMVEKQKQQE 206
           + ER ++ Q +RE+      E+ K++E
Sbjct: 237 KTEREREKQAERERASERETERDKERE 263



 Score = 92.4 bits (228), Expect = 6e-19
 Identities = 57/184 (30%), Positives = 92/184 (50%), Gaps = 4/184 (2%)

Query: 24  HKSEEHNDKEHSSDKGRERLNSSENGE-DRHKRKERKSSRGRSHSRSRSRER-RHRSRSR 81
           HK  + +D+E +  K RER       E +  +++ER+  + R   R R RER R R + R
Sbjct: 46  HKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKER 105

Query: 82  ERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRS 141
           ER+  R R R+R+K R+R +ER++   R  ER R  R     R R R R   + R R   
Sbjct: 106 ERQTDRERDRQREKERNRQKERERETEREGERGRD-RQTDGQRERERQRDAEKERERQTD 164

Query: 142 RDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEK 201
           R+R+++ E+ R+  R   +       R R    +  +   R  ER ++ + +RE E   +
Sbjct: 165 RERQRQTERNRQKEREREKNRQERRERERQREKE-NKTEDRHSERGRERERERETETETE 223

Query: 202 QKQQ 205
           +K+Q
Sbjct: 224 RKRQ 227



 Score = 91.7 bits (226), Expect = 1e-18
 Identities = 56/206 (27%), Positives = 103/206 (50%), Gaps = 16/206 (7%)

Query: 15  ESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRER 74
           +  D+   + K  E   ++  +++  +R       +DRH++++R   R R   + R R+ 
Sbjct: 50  DGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQT 109

Query: 75  -RHRSRSRERKKSRSRSRERKKSR--SRSRERKKSRSRSRERKR---RIRSRSRSRSRHR 128
            R R R RE++++R + RER+  R   R R+R+    R RER+R   + R R   R R R
Sbjct: 110 DRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQR 169

Query: 129 HRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGR--------NTAMDAQEAL 180
              R+R + R R ++R++R E+ R+  +  ++T      RGR         T  + +   
Sbjct: 170 QTERNRQKEREREKNRQERRERERQREKE-NKTEDRHSERGRERERERETETETERKRQT 228

Query: 181 ARRLERAKKLQEQREKEMVEKQKQQE 206
            R  +R +K + +REK+  E+++  E
Sbjct: 229 DRERDRQRKTEREREKQ-AERERASE 253



 Score = 90.1 bits (222), Expect = 3e-18
 Identities = 53/198 (26%), Positives = 97/198 (48%), Gaps = 8/198 (4%)

Query: 12  RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRS 71
           R  + + +  +  + E   + E   ++GR+R    +   +R +  E++  R     R R 
Sbjct: 111 RERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQ 170

Query: 72  RERRHRSRSRERKKSRSRSRERKKSR---SRSRERKKSRSRSRERKRRIRSRSRSRSRHR 128
            ER +R + RER+K+R   RER++ R   +++ +R   R R RER+R   + +    R R
Sbjct: 171 TER-NRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETET---ERKR 226

Query: 129 HRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMD-AQEALARRLERA 187
              R R R R   R+R+K+ E+ R   R   R       R R+   D  Q+   R+ +R 
Sbjct: 227 QTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRK 286

Query: 188 KKLQEQREKEMVEKQKQQ 205
           ++ + +R++E   K+++Q
Sbjct: 287 RQRRTERDRETERKRERQ 304



 Score = 86.3 bits (212), Expect = 4e-17
 Identities = 53/205 (25%), Positives = 85/205 (41%), Gaps = 23/205 (11%)

Query: 9   KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 68
           K+  R   +D+   + + E     +    +  ER   +E   +R + +ER+  R R   R
Sbjct: 260 KERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRER 319

Query: 69  SRSRERRHRSRSRERKKSRSRSRERKKSRS----------------RSRERKKSRSRSRE 112
            R RER  R R RE ++ R + RERK+ R                 R  ER++ R R R+
Sbjct: 320 ERERERE-RERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERD 378

Query: 113 RKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNT 172
           R+       R R R R R + R R   + RD ++  EK R       R       RGR  
Sbjct: 379 RQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQR------EREKDRESERGRER 432

Query: 173 AMDAQEALARRLERAKKLQEQREKE 197
             + ++   R  +R ++   Q  ++
Sbjct: 433 GREREKQKGRERDRERQTDRQAGRQ 457



 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 58/179 (32%), Positives = 83/179 (46%), Gaps = 14/179 (7%)

Query: 37  DKGRERLNSSENGEDRHKRKERKSSRG--RSHSRSRSRERRHRSRSRERKKSRSRSRERK 94
           D  R R  S E+   R   +  K + G  R  +R + RERR   R  ER+  R R R R+
Sbjct: 25  DFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRRE 84

Query: 95  KSRSRSRERKKSRSRSRERKR-------RIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKR 147
           K R R R+R + R R RE++R       R R R + R+R + R R   R   R RDR+  
Sbjct: 85  KDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTD 144

Query: 148 IEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQE 206
            ++ R   R   +       R R    +      R  ER K  QE+RE+   E+Q+++E
Sbjct: 145 GQRERERQRDAEKERERQTDRERQRQTERNRQKER--EREKNRQERRER---ERQREKE 198



 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 54/174 (31%), Positives = 85/174 (48%), Gaps = 19/174 (10%)

Query: 17  KDKSSKKHKSEEHNDK-EHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRE-- 73
           +++  ++ +  E N K E   ++ RER    E   DR K +ERK  R     R R+R+  
Sbjct: 301 RERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTG 360

Query: 74  -----RRHRSRSRERKKSRSRSRERK-KSRSRSRERKKSRSRSRER---------KRRIR 118
                +  R R RER++ R  +RER+ + R R R+R+K R R  E+         K+R R
Sbjct: 361 REGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQRER 420

Query: 119 SRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRT-PSPPPFRGRN 171
            + R   R R R R R + + R RDR+++ ++     R  S    +PPP   R+
Sbjct: 421 EKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARS 474



 Score = 82.4 bits (202), Expect = 6e-16
 Identities = 49/178 (27%), Positives = 82/178 (46%), Gaps = 7/178 (3%)

Query: 9   KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 68
           K+ RR E   ++ +K + +   ++E   ++ RER    E   +R + ++R++ R R   R
Sbjct: 286 KRQRRTERDRETERKRERQRERERERERNRKRER----ERERERERERQRETERDREKER 341

Query: 69  SRSRERR---HRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRS 125
            R R+R+    R R+R+  +   R  ER++ R R R+R+ +R R    + R R R + R 
Sbjct: 342 ERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERE 401

Query: 126 RHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARR 183
           R   + R   R   + R+R+K  E  R   R   R       R R    D Q    R+
Sbjct: 402 RQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRK 459



 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 32/108 (29%), Positives = 57/108 (52%), Gaps = 9/108 (8%)

Query: 9   KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 68
           ++GRR   +++  ++ +  +   +    ++ R+R        DR K +ER++ + R   R
Sbjct: 361 REGRRQAERERERERERDRQSAREREERERDRDR--------DRQKERERQTEKDRDGQR 412

Query: 69  SRSRER-RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKR 115
              ++R R + R  ER + R R RE++K R R RER+  R   R+RKR
Sbjct: 413 ETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKR 460



 Score = 55.8 bits (133), Expect = 6e-08
 Identities = 26/100 (26%), Positives = 49/100 (49%), Gaps = 3/100 (3%)

Query: 9   KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 68
           +Q  R   +++   +  + E  ++E   D+ R++    +  +DR  ++E +  R R   R
Sbjct: 365 RQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDR 424

Query: 69  SRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRS 108
                 R R R RER+K + R R+R++   R   R++ RS
Sbjct: 425 E---SERGRERGREREKQKGRERDRERQTDRQAGRQRKRS 461



 Score = 37.7 bits (86), Expect = 0.017
 Identities = 29/129 (22%), Positives = 52/129 (40%), Gaps = 5/129 (3%)

Query: 9   KQGRRHESKDK-----SSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRG 63
           K+  R   KD+     + K+ + E+  + E   ++GRER        DR ++ +R++ R 
Sbjct: 398 KERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQ 457

Query: 64  RSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRS 123
           R  S          +RS   +   +R     + +S   + K + +R    +    SR R 
Sbjct: 458 RKRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWKSSPEDPKAASTRFPWGRPAKASRGRV 517

Query: 124 RSRHRHRTR 132
             R R   R
Sbjct: 518 AGRRRWEPR 526


>gi|52426743 cisplatin resistance-associated overexpressed protein
           [Homo sapiens]
          Length = 432

 Score =  103 bits (257), Expect = 3e-22
 Identities = 67/188 (35%), Positives = 95/188 (50%), Gaps = 10/188 (5%)

Query: 15  ESKDKSSKKHKSEEHNDKEHSSDKGRE-RLNSSENGEDRHKRKERKSSRGRSHSRSRSRE 73
           E K+K  K+ +  + +++     + RE R    E   +  +RK R+    R   R+R RE
Sbjct: 229 ELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRE 288

Query: 74  RRHRSRSRERKKSRSR----SRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRH 129
           RR RSRSR R  SR+     SR R   RSRSRER++SRSR R      RSRS  RS  +H
Sbjct: 289 RRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRR-----RSRSHDRSERKH 343

Query: 130 RTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKK 189
           R+RSR R RS+SRDRK    + +   R   R       RG +    + ++ +R  +    
Sbjct: 344 RSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDT 403

Query: 190 LQEQREKE 197
             E +E +
Sbjct: 404 NTESKESD 411



 Score =  100 bits (250), Expect = 2e-21
 Identities = 58/148 (39%), Positives = 92/148 (62%), Gaps = 10/148 (6%)

Query: 12  RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRK--ERKSSRGRSHSRS 69
           R  E +++  K+ + EE  +KE + D+ R + + S +   RH  +  +R+ SR R H RS
Sbjct: 261 REREREERERKRRREEEEREKERARDRERRKRSRSRS---RHSSRTSDRRCSRSRDHKRS 317

Query: 70  RSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRH 129
           RSRERR RSRSR+R++SRS  R  +K RSRSR+R++S+SR R   +  + RS+SR R + 
Sbjct: 318 RSRERR-RSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDR---KSYKHRSKSRDREQD 373

Query: 130 RTRSRSRTRSRSRDRKKRIEKPRRFSRS 157
           R +S+ + +  S D+K  ++   R  +S
Sbjct: 374 R-KSKEKEKRGSDDKKSSVKSGSREKQS 400



 Score = 95.9 bits (237), Expect = 5e-20
 Identities = 65/155 (41%), Positives = 91/155 (58%), Gaps = 11/155 (7%)

Query: 9   KQGRRHESKDKSSK-KHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHS 67
           K  +R E  D+  + K + +E  ++E   ++ RE        E+  + KER   R R   
Sbjct: 233 KLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRER-RK 291

Query: 68  RSRSRERRHRSRSRERKKSRSR----SRERKKSRSRSRERKKSRSRSR-ERKRRIRSRSR 122
           RSRSR R H SR+ +R+ SRSR    SR R++ RSRSR+R++SRS  R ERK R RSR R
Sbjct: 292 RSRSRSR-HSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDR 350

Query: 123 SRSRHRHRT--RSRSRTRSRSRDRKKRIEKPRRFS 155
            RS+ R R   + RS++R R +DRK + EK +R S
Sbjct: 351 RRSKSRDRKSYKHRSKSRDREQDRKSK-EKEKRGS 384



 Score = 91.3 bits (225), Expect = 1e-18
 Identities = 60/151 (39%), Positives = 87/151 (57%), Gaps = 13/151 (8%)

Query: 8   LKQGRRHESKDKSSKKHKSE-EHNDKEHSSDKGRERLNSSENGEDRHK-----RKERKSS 61
           L++      +D+  KK K E E  +KE   ++           E+R K     R+ RK S
Sbjct: 234 LRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRS 293

Query: 62  RGRSHSRSRSRERRHRSRSRERKKSRSR----SRERKKSRSRSRERKKSRSRSRERKRRI 117
           R RS   SR+ +RR  SRSR+ K+SRSR    SR R + RSRS +R + + RSR R RR 
Sbjct: 294 RSRSRHSSRTSDRRC-SRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRR- 351

Query: 118 RSRSRSRSRHRHRTRSRSRTRSR-SRDRKKR 147
           RS+SR R  ++HR++SR R + R S++++KR
Sbjct: 352 RSKSRDRKSYKHRSKSRDREQDRKSKEKEKR 382



 Score = 86.3 bits (212), Expect = 4e-17
 Identities = 58/159 (36%), Positives = 86/159 (54%), Gaps = 12/159 (7%)

Query: 50  EDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSR 109
           E   KR E      R     + RE R + R RER++     RERK+ R    ER+K R+R
Sbjct: 232 EKLRKRTEEPDRDERLKKEKQEREEREKEREREREE-----RERKRRREEE-EREKERAR 285

Query: 110 SRERKRRIRSRSR--SRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPF 167
            RER++R RSRSR  SR+  R  +RSR   RSRSR+R++   + RR SRS  R+      
Sbjct: 286 DRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSER---- 341

Query: 168 RGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQE 206
           + R+ + D + + +R  +  K   + R++E   K K++E
Sbjct: 342 KHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKE 380



 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 36/126 (28%), Positives = 63/126 (50%), Gaps = 9/126 (7%)

Query: 12  RRHESKDKSSKKHKSEEHN---DKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 68
           RR  S+ +S    ++ +      ++H   + RER  S      R +  +R   + RS SR
Sbjct: 289 RRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSR 348

Query: 69  SRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHR 128
            R   RR +SR R+  K RS+SR+R++ R   + ++K +  S ++K  ++S SR +    
Sbjct: 349 DR---RRSKSRDRKSYKHRSKSRDREQDR---KSKEKEKRGSDDKKSSVKSGSREKQSED 402

Query: 129 HRTRSR 134
             T S+
Sbjct: 403 TNTESK 408



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 29/110 (26%), Positives = 50/110 (45%), Gaps = 20/110 (18%)

Query: 12  RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRS 71
           RR  S D+S +KH+S           + R+R         R K ++RKS + RS SR R 
Sbjct: 331 RRSRSHDRSERKHRS-----------RSRDR--------RRSKSRDRKSYKHRSKSRDRE 371

Query: 72  RERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRS 121
           ++R+ + + + R     +S  +  SR +  E   + S+  + K  +   S
Sbjct: 372 QDRKSKEKEK-RGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTS 420


>gi|19923485 cisplatin resistance-associated overexpressed protein
           [Homo sapiens]
          Length = 432

 Score =  103 bits (257), Expect = 3e-22
 Identities = 67/188 (35%), Positives = 95/188 (50%), Gaps = 10/188 (5%)

Query: 15  ESKDKSSKKHKSEEHNDKEHSSDKGRE-RLNSSENGEDRHKRKERKSSRGRSHSRSRSRE 73
           E K+K  K+ +  + +++     + RE R    E   +  +RK R+    R   R+R RE
Sbjct: 229 ELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRE 288

Query: 74  RRHRSRSRERKKSRSR----SRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRH 129
           RR RSRSR R  SR+     SR R   RSRSRER++SRSR R      RSRS  RS  +H
Sbjct: 289 RRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRR-----RSRSHDRSERKH 343

Query: 130 RTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKK 189
           R+RSR R RS+SRDRK    + +   R   R       RG +    + ++ +R  +    
Sbjct: 344 RSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDT 403

Query: 190 LQEQREKE 197
             E +E +
Sbjct: 404 NTESKESD 411



 Score =  100 bits (250), Expect = 2e-21
 Identities = 58/148 (39%), Positives = 92/148 (62%), Gaps = 10/148 (6%)

Query: 12  RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRK--ERKSSRGRSHSRS 69
           R  E +++  K+ + EE  +KE + D+ R + + S +   RH  +  +R+ SR R H RS
Sbjct: 261 REREREERERKRRREEEEREKERARDRERRKRSRSRS---RHSSRTSDRRCSRSRDHKRS 317

Query: 70  RSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRH 129
           RSRERR RSRSR+R++SRS  R  +K RSRSR+R++S+SR R   +  + RS+SR R + 
Sbjct: 318 RSRERR-RSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDR---KSYKHRSKSRDREQD 373

Query: 130 RTRSRSRTRSRSRDRKKRIEKPRRFSRS 157
           R +S+ + +  S D+K  ++   R  +S
Sbjct: 374 R-KSKEKEKRGSDDKKSSVKSGSREKQS 400



 Score = 95.9 bits (237), Expect = 5e-20
 Identities = 65/155 (41%), Positives = 91/155 (58%), Gaps = 11/155 (7%)

Query: 9   KQGRRHESKDKSSK-KHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHS 67
           K  +R E  D+  + K + +E  ++E   ++ RE        E+  + KER   R R   
Sbjct: 233 KLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRER-RK 291

Query: 68  RSRSRERRHRSRSRERKKSRSR----SRERKKSRSRSRERKKSRSRSR-ERKRRIRSRSR 122
           RSRSR R H SR+ +R+ SRSR    SR R++ RSRSR+R++SRS  R ERK R RSR R
Sbjct: 292 RSRSRSR-HSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDR 350

Query: 123 SRSRHRHRT--RSRSRTRSRSRDRKKRIEKPRRFS 155
            RS+ R R   + RS++R R +DRK + EK +R S
Sbjct: 351 RRSKSRDRKSYKHRSKSRDREQDRKSK-EKEKRGS 384



 Score = 91.3 bits (225), Expect = 1e-18
 Identities = 60/151 (39%), Positives = 87/151 (57%), Gaps = 13/151 (8%)

Query: 8   LKQGRRHESKDKSSKKHKSE-EHNDKEHSSDKGRERLNSSENGEDRHK-----RKERKSS 61
           L++      +D+  KK K E E  +KE   ++           E+R K     R+ RK S
Sbjct: 234 LRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRS 293

Query: 62  RGRSHSRSRSRERRHRSRSRERKKSRSR----SRERKKSRSRSRERKKSRSRSRERKRRI 117
           R RS   SR+ +RR  SRSR+ K+SRSR    SR R + RSRS +R + + RSR R RR 
Sbjct: 294 RSRSRHSSRTSDRRC-SRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRR- 351

Query: 118 RSRSRSRSRHRHRTRSRSRTRSR-SRDRKKR 147
           RS+SR R  ++HR++SR R + R S++++KR
Sbjct: 352 RSKSRDRKSYKHRSKSRDREQDRKSKEKEKR 382



 Score = 86.3 bits (212), Expect = 4e-17
 Identities = 58/159 (36%), Positives = 86/159 (54%), Gaps = 12/159 (7%)

Query: 50  EDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSR 109
           E   KR E      R     + RE R + R RER++     RERK+ R    ER+K R+R
Sbjct: 232 EKLRKRTEEPDRDERLKKEKQEREEREKEREREREE-----RERKRRREEE-EREKERAR 285

Query: 110 SRERKRRIRSRSR--SRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPF 167
            RER++R RSRSR  SR+  R  +RSR   RSRSR+R++   + RR SRS  R+      
Sbjct: 286 DRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSER---- 341

Query: 168 RGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQE 206
           + R+ + D + + +R  +  K   + R++E   K K++E
Sbjct: 342 KHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKE 380



 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 36/126 (28%), Positives = 63/126 (50%), Gaps = 9/126 (7%)

Query: 12  RRHESKDKSSKKHKSEEHN---DKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 68
           RR  S+ +S    ++ +      ++H   + RER  S      R +  +R   + RS SR
Sbjct: 289 RRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSR 348

Query: 69  SRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHR 128
            R   RR +SR R+  K RS+SR+R++ R   + ++K +  S ++K  ++S SR +    
Sbjct: 349 DR---RRSKSRDRKSYKHRSKSRDREQDR---KSKEKEKRGSDDKKSSVKSGSREKQSED 402

Query: 129 HRTRSR 134
             T S+
Sbjct: 403 TNTESK 408



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 29/110 (26%), Positives = 50/110 (45%), Gaps = 20/110 (18%)

Query: 12  RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRS 71
           RR  S D+S +KH+S           + R+R         R K ++RKS + RS SR R 
Sbjct: 331 RRSRSHDRSERKHRS-----------RSRDR--------RRSKSRDRKSYKHRSKSRDRE 371

Query: 72  RERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRS 121
           ++R+ + + + R     +S  +  SR +  E   + S+  + K  +   S
Sbjct: 372 QDRKSKEKEK-RGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTS 420


>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
           [Homo sapiens]
          Length = 624

 Score =  102 bits (254), Expect = 6e-22
 Identities = 58/189 (30%), Positives = 101/189 (53%), Gaps = 10/189 (5%)

Query: 19  KSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRER-RHR 77
           +S K ++ +    + H+  K R    SS     R KR + K  R RSH+RSRSR++ R R
Sbjct: 296 ESGKSNERKGGRSRSHTRSKSR----SSSKSHSRRKRSQSKH-RSRSHNRSRSRQKDRRR 350

Query: 78  SRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRT 137
           S+S  +K+S+SR R + +SRS SR+++K      + K R++ + R + R R + R + + 
Sbjct: 351 SKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKE 410

Query: 138 RSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKE 197
           R +++DR K  EK R   +   R       R +    D  +   +  ++ K+ ++ R KE
Sbjct: 411 RGKNKDRDKEREKDREKDKEKDRERE----REKEHEKDRDKEKEKEQDKEKEREKDRSKE 466

Query: 198 MVEKQKQQE 206
           + EK+K+ +
Sbjct: 467 IDEKRKKDK 475



 Score = 93.6 bits (231), Expect = 3e-19
 Identities = 57/210 (27%), Positives = 99/210 (47%), Gaps = 26/210 (12%)

Query: 12  RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRS 71
           + H  + +S  KH+S  HN +  S  K R R  S       HK++ +   R +S SRS S
Sbjct: 321 KSHSRRKRSQSKHRSRSHN-RSRSRQKDRRRSKSP------HKKRSKSRERRKSRSRSHS 373

Query: 72  RERR----------------HRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKR 115
           R++R                 R + RER+K R + +ER K++ R +ER+K R + +E+ R
Sbjct: 374 RDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDR 433

Query: 116 -RIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAM 174
            R R +   + R + + + + + + R +DR K I++ R+  +  SRTP P  +     + 
Sbjct: 434 EREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKK-SRTP-PRSYNASRRSR 491

Query: 175 DAQEALARRLERAKKLQEQREKEMVEKQKQ 204
            +     RR  R+     +  K +  K  +
Sbjct: 492 SSSRERRRRRSRSSSRSPRTSKTIKRKSSR 521



 Score = 92.8 bits (229), Expect = 4e-19
 Identities = 59/197 (29%), Positives = 97/197 (49%), Gaps = 17/197 (8%)

Query: 9   KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 68
           ++ R+  S+  S  K K      KE    K ++R    E  ++R K KER  ++ R   R
Sbjct: 362 RERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKER 421

Query: 69  SRSRER---RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRS 125
            + RE+   + R R RE++  + R +E++K + + +ER+K RS+  + KR+   +SR+  
Sbjct: 422 EKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPP 481

Query: 126 R-----HRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEAL 180
           R      R R+ SR R R RSR   +     +   R  SR+PSP   R RN      +  
Sbjct: 482 RSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSP---RSRN------KKD 532

Query: 181 ARRLERAKKLQEQREKE 197
            +R +    + E+RE+E
Sbjct: 533 KKREKERDHISERRERE 549



 Score = 85.9 bits (211), Expect = 5e-17
 Identities = 62/203 (30%), Positives = 104/203 (51%), Gaps = 15/203 (7%)

Query: 8   LKQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHS 67
           +K+  R + KD+  K+ + E+  +KE    K ++R    E   ++ K K+R+  R + H 
Sbjct: 384 IKEKERVKEKDRE-KEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHE 442

Query: 68  RSRSRER-RHRSRSRERKKSRSRS-----RERKKSRSRSRE---RKKSRSRSRERKRRIR 118
           + R +E+ + + + +ER+K RS+      ++ KKSR+  R     ++SRS SRER+RR R
Sbjct: 443 KDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRR-R 501

Query: 119 SRSRSRSRHRHRTRSRSRTRS---RSRDRK-KRIEKPRRFSRSLSRTPSPPPFRGRNTAM 174
           SRS SRS    +T  R  +RS   RSR++K K+ EK R               R  +   
Sbjct: 502 SRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDR 561

Query: 175 DAQEALARRLERAKKLQEQREKE 197
           D +E L +     K+ +  +E +
Sbjct: 562 DGKEKLEKNSTSLKEKEHNKEPD 584



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 35/138 (25%), Positives = 56/138 (40%), Gaps = 11/138 (7%)

Query: 8   LKQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHS 67
           + + R+ + K ++  +  +     +  S ++ R R  SS       K  +RKSSR  S  
Sbjct: 467 IDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPS-- 524

Query: 68  RSRSRERRHRSRSRERKK-SRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSR 126
             RSR ++ + R +ER   S  R RER  S  +S       S  R+ K ++   S S   
Sbjct: 525 -PRSRNKKDKKREKERDHISERRERERSTSMRKS-------SNDRDGKEKLEKNSTSLKE 576

Query: 127 HRHRTRSRSRTRSRSRDR 144
             H     S       D+
Sbjct: 577 KEHNKEPDSSVSKEVDDK 594


>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
           [Homo sapiens]
          Length = 508

 Score =  102 bits (254), Expect = 6e-22
 Identities = 58/189 (30%), Positives = 101/189 (53%), Gaps = 10/189 (5%)

Query: 19  KSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRER-RHR 77
           +S K ++ +    + H+  K R    SS     R KR + K  R RSH+RSRSR++ R R
Sbjct: 180 ESGKSNERKGGRSRSHTRSKSR----SSSKSHSRRKRSQSKH-RSRSHNRSRSRQKDRRR 234

Query: 78  SRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRT 137
           S+S  +K+S+SR R + +SRS SR+++K      + K R++ + R + R R + R + + 
Sbjct: 235 SKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKE 294

Query: 138 RSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKE 197
           R +++DR K  EK R   +   R       R +    D  +   +  ++ K+ ++ R KE
Sbjct: 295 RGKNKDRDKEREKDREKDKEKDRERE----REKEHEKDRDKEKEKEQDKEKEREKDRSKE 350

Query: 198 MVEKQKQQE 206
           + EK+K+ +
Sbjct: 351 IDEKRKKDK 359



 Score = 93.6 bits (231), Expect = 3e-19
 Identities = 57/210 (27%), Positives = 99/210 (47%), Gaps = 26/210 (12%)

Query: 12  RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRS 71
           + H  + +S  KH+S  HN +  S  K R R  S       HK++ +   R +S SRS S
Sbjct: 205 KSHSRRKRSQSKHRSRSHN-RSRSRQKDRRRSKSP------HKKRSKSRERRKSRSRSHS 257

Query: 72  RERR----------------HRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKR 115
           R++R                 R + RER+K R + +ER K++ R +ER+K R + +E+ R
Sbjct: 258 RDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDR 317

Query: 116 -RIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAM 174
            R R +   + R + + + + + + R +DR K I++ R+  +  SRTP P  +     + 
Sbjct: 318 EREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKK-SRTP-PRSYNASRRSR 375

Query: 175 DAQEALARRLERAKKLQEQREKEMVEKQKQ 204
            +     RR  R+     +  K +  K  +
Sbjct: 376 SSSRERRRRRSRSSSRSPRTSKTIKRKSSR 405



 Score = 92.8 bits (229), Expect = 4e-19
 Identities = 59/197 (29%), Positives = 97/197 (49%), Gaps = 17/197 (8%)

Query: 9   KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 68
           ++ R+  S+  S  K K      KE    K ++R    E  ++R K KER  ++ R   R
Sbjct: 246 RERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKER 305

Query: 69  SRSRER---RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRS 125
            + RE+   + R R RE++  + R +E++K + + +ER+K RS+  + KR+   +SR+  
Sbjct: 306 EKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPP 365

Query: 126 R-----HRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEAL 180
           R      R R+ SR R R RSR   +     +   R  SR+PSP   R RN      +  
Sbjct: 366 RSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSP---RSRN------KKD 416

Query: 181 ARRLERAKKLQEQREKE 197
            +R +    + E+RE+E
Sbjct: 417 KKREKERDHISERRERE 433



 Score = 85.9 bits (211), Expect = 5e-17
 Identities = 62/203 (30%), Positives = 104/203 (51%), Gaps = 15/203 (7%)

Query: 8   LKQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHS 67
           +K+  R + KD+  K+ + E+  +KE    K ++R    E   ++ K K+R+  R + H 
Sbjct: 268 IKEKERVKEKDRE-KEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHE 326

Query: 68  RSRSRER-RHRSRSRERKKSRSRS-----RERKKSRSRSRE---RKKSRSRSRERKRRIR 118
           + R +E+ + + + +ER+K RS+      ++ KKSR+  R     ++SRS SRER+RR R
Sbjct: 327 KDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRR-R 385

Query: 119 SRSRSRSRHRHRTRSRSRTRS---RSRDRK-KRIEKPRRFSRSLSRTPSPPPFRGRNTAM 174
           SRS SRS    +T  R  +RS   RSR++K K+ EK R               R  +   
Sbjct: 386 SRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDR 445

Query: 175 DAQEALARRLERAKKLQEQREKE 197
           D +E L +     K+ +  +E +
Sbjct: 446 DGKEKLEKNSTSLKEKEHNKEPD 468



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 35/138 (25%), Positives = 56/138 (40%), Gaps = 11/138 (7%)

Query: 8   LKQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHS 67
           + + R+ + K ++  +  +     +  S ++ R R  SS       K  +RKSSR  S  
Sbjct: 351 IDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPS-- 408

Query: 68  RSRSRERRHRSRSRERKK-SRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSR 126
             RSR ++ + R +ER   S  R RER  S  +S       S  R+ K ++   S S   
Sbjct: 409 -PRSRNKKDKKREKERDHISERRERERSTSMRKS-------SNDRDGKEKLEKNSTSLKE 460

Query: 127 HRHRTRSRSRTRSRSRDR 144
             H     S       D+
Sbjct: 461 KEHNKEPDSSVSKEVDDK 478


>gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]
          Length = 344

 Score =  100 bits (249), Expect = 2e-21
 Identities = 73/164 (44%), Positives = 96/164 (58%), Gaps = 21/164 (12%)

Query: 50  EDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSR 109
           ED+ +   R+S  G   SRSRSR RR RSRSR R+ SRSRSR   KSRSRSR R K RSR
Sbjct: 180 EDKPRTSHRRSYSG---SRSRSRSRR-RSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSR 235

Query: 110 SRERKRRIRSRSRS-----RSRHRH-RTRS-----RSRTRSRSRDRKKRIE---KPRRFS 155
           SR + R+ RS+S+S     R  H H R+RS     +SR+RSRSR  K+  +   K +  S
Sbjct: 236 SRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRS 295

Query: 156 RSLSRTPSP---PPFRGRNTAMDAQEALARRLERAKKLQEQREK 196
           RS SR+ SP   PP + R+ +   + A +R   R++     R +
Sbjct: 296 RSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSR 339



 Score = 85.9 bits (211), Expect = 5e-17
 Identities = 71/199 (35%), Positives = 101/199 (50%), Gaps = 17/199 (8%)

Query: 3   RTNFFLKQGRRHESKDKSSKKHKSEEHNDKEHS--SDKGRERLNSSENGEDRHKRKERKS 60
           RTN  + + R +    ++  K    E N +      DK R     S +G     R  R+S
Sbjct: 145 RTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRS 204

Query: 61  -SRGRSHSRSRSRE-RRHRSRSRERKKSRSRSRER-KKSRSRSRERKKS--------RSR 109
            SR R  SRSRSR   + RSRSR R K RSRSR + +KSRS+S+ + KS        RSR
Sbjct: 205 RSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSR 264

Query: 110 SRERKRRIRSRSRSRS-RHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFR 168
           S++   + RSRSRSRS +   +   +S++RSRS+ R      P     S +R+ SPPP R
Sbjct: 265 SKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRS---NSPLPVPPSKARSVSPPPKR 321

Query: 169 GRNTAMDAQEALARRLERA 187
             + +     + +R   R+
Sbjct: 322 ATSRSRSRSRSKSRSRSRS 340



 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 62/165 (37%), Positives = 80/165 (48%), Gaps = 36/165 (21%)

Query: 15  ESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRER 74
           E K ++S +        +  S  + R R   S     R   K R  SR RS  RSRSR +
Sbjct: 180 EDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSK 239

Query: 75  RHRSRSRERKK----------SRSRSR-ERKKSRSRSRERK---------KSRSRSRERK 114
             +SRS+ + K          SRSRS+ E +KSRSRSR R          KS+SRSR + 
Sbjct: 240 GRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQS 299

Query: 115 R----------RIRS------RSRSRSRHRHRTRSRSRTRSRSRD 143
           R          + RS      R+ SRSR R R++SRSR+RS SRD
Sbjct: 300 RSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSRD 344



 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 49/142 (34%), Positives = 61/142 (42%), Gaps = 38/142 (26%)

Query: 12  RRHESKDKSSKKHKSE---EHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRG-RSHS 67
           RR  S+ + S + +S    +   +  S  KGR R  S         + + KS RG  SHS
Sbjct: 202 RRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHS 261

Query: 68  RSRSRERRHRSRSRERK-------------KSRSRSRERKKS------------------ 96
           RSRS++   +SRSR R              KSRSRS+ R  S                  
Sbjct: 262 RSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKR 321

Query: 97  ---RSRSRERKKSRSRSRERKR 115
              RSRSR R KSRSRSR   R
Sbjct: 322 ATSRSRSRSRSKSRSRSRSSSR 343



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 40/105 (38%), Positives = 52/105 (49%), Gaps = 7/105 (6%)

Query: 10  QGRRHESKDKSSKKHKSEEHNDKEHSS----DKGRERLNS---SENGEDRHKRKERKSSR 62
           +GR+  SK KS  K     H+     S    +K R R  S    ENG+   K K R  S+
Sbjct: 239 KGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQ 298

Query: 63  GRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSR 107
            RS+S       + RS S   K++ SRSR R +S+SRSR R  SR
Sbjct: 299 SRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSR 343



 Score = 34.3 bits (77), Expect = 0.19
 Identities = 24/92 (26%), Positives = 41/92 (44%), Gaps = 1/92 (1%)

Query: 115 RRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAM 174
           R I  + R+ S  R  + SRSR+RSR R R +     R  SRS+S++ S    R +  + 
Sbjct: 177 RLIEDKPRT-SHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSR 235

Query: 175 DAQEALARRLERAKKLQEQREKEMVEKQKQQE 206
              +    R +   K +  R      + + ++
Sbjct: 236 SRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKD 267


>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
           containing B [Homo sapiens]
          Length = 546

 Score =  100 bits (248), Expect = 3e-21
 Identities = 72/233 (30%), Positives = 107/233 (45%), Gaps = 36/233 (15%)

Query: 9   KQGRRHESKDKSSKKHKSEEHNDKEHSS-DKGRERLNSSENGEDRHKRKERKSSRGRSHS 67
           ++G    S D+  ++ K  +  ++E    +K R R  S + G +R + + R+  R RS S
Sbjct: 283 REGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRS 342

Query: 68  RSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSR------- 120
           R R  +RR R R RE++  R R R+R   + R  ER+K R RSRER +  RSR       
Sbjct: 343 RDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKK 402

Query: 121 -----------------------SRSRSRHR-HRTRSRSRT---RSRSRDRKKRIEKPRR 153
                                  SRSRSR R HR+RSRSR    RSRSR ++K   K + 
Sbjct: 403 HKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKS-SKHKN 461

Query: 154 FSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQE 206
            S+  S   S    +GR  +++  +       + K  +  R KE   K+   +
Sbjct: 462 ESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSD 514



 Score = 96.7 bits (239), Expect = 3e-20
 Identities = 65/207 (31%), Positives = 105/207 (50%), Gaps = 17/207 (8%)

Query: 13  RHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSH-SRSRS 71
           R  S+D+   +   +   +KE+   + R+R    E G +R K +ER   R +   SR   
Sbjct: 339 RSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEV 398

Query: 72  RERRH-------------RSRSRERKKSRSRSRERK-KSRSRSRER-KKSRSRSRERKRR 116
            E++H             R   +E+K SRSRSRERK +SRSRSR   K+SRSRS+E+  +
Sbjct: 399 EEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSK 458

Query: 117 IRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDA 176
            ++ S+ +S  R R+ S+ RT S  + +K+     +  SR  SR+      R  + + D 
Sbjct: 459 HKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQ 518

Query: 177 QEALARRLERAKKLQEQREKEMVEKQK 203
            +   RR  ++ + QE +EK+   K +
Sbjct: 519 SDKHDRRRSQSIE-QESQEKQHKNKDE 544



 Score = 93.6 bits (231), Expect = 3e-19
 Identities = 65/219 (29%), Positives = 102/219 (46%), Gaps = 23/219 (10%)

Query: 12  RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRS 71
           RR  S+++   + +S +        D+ RE+ N      DR   KER + R +   RSR 
Sbjct: 328 RRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRE 387

Query: 72  RERRHRSRS----RERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRS-----R 122
           R +  RSR     ++ K+ +   R R   R   +E+K SRSRSRERK R RSRS     R
Sbjct: 388 RSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKR 447

Query: 123 SRSRHRHRT---------RSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTA 173
           SRSR + ++         +S  R+RS S+ R   +EK ++   S S+  S    R +  +
Sbjct: 448 SRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERS 507

Query: 174 -----MDAQEALARRLERAKKLQEQREKEMVEKQKQQEI 207
                 D+++   +   R  +  EQ  +E   K K + +
Sbjct: 508 HKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNKDETV 546



 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 64/210 (30%), Positives = 93/210 (44%), Gaps = 27/210 (12%)

Query: 12  RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRS 71
           RR  S  +S ++ +S  H+ + H S           +  DR   +E++  R    ++ R 
Sbjct: 264 RRSLSPRRSPRRSRSRSHHREGHGS-----------SSFDRELEREKERQRLEREAKERE 312

Query: 72  RER-----------RHRSRSRERKKSRSRSRERK-KSRSRSRERKKSRSRSRERKRRI-R 118
           +ER           R RSRSRER +SRSRSR+RK   R R RER+K   R R R R   +
Sbjct: 313 KERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDK 372

Query: 119 SRSRSRSRHRHRTRSRS---RTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMD 175
            R   R + R R+R RS   R+R    ++K + +K  R  R   R         R+ + +
Sbjct: 373 ERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRE 432

Query: 176 AQEALARRLERAKKLQEQREKEMVEKQKQQ 205
            +     R   A K    R KE   K K +
Sbjct: 433 RKHRSRSRSRNAGKRSRSRSKEKSSKHKNE 462



 Score = 82.0 bits (201), Expect = 8e-16
 Identities = 61/159 (38%), Positives = 83/159 (52%), Gaps = 8/159 (5%)

Query: 51  DRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRS 110
           DRH  + R  S  RS S  RS  RR RSRS  R+   S S +R+  R + R+R +  ++ 
Sbjct: 252 DRHVERRRSRSPRRSLSPRRS-PRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKE 310

Query: 111 RERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGR 170
           RE++RR RSRS  R   R R+RSR R RSRSR R +   K  R  R   R       R R
Sbjct: 311 REKERR-RSRSIDRGLERRRSRSRERHRSRSRSRDR---KGDRRDRDREREKENERGRRR 366

Query: 171 NTAMDAQEALARRLERAK---KLQEQREKEMVEKQKQQE 206
           +   D +    R  ER +   + +EQR +  VE++K +E
Sbjct: 367 DRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKE 405



 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 37/140 (26%), Positives = 64/140 (45%), Gaps = 14/140 (10%)

Query: 9   KQGRRHESKDKSSKKHKSE--------EHNDKEHSSDKGRERLNSSENGEDRHKRKERKS 60
           K  RRH    + SKK K          +H  +  S + G+   + S+    +HK + ++ 
Sbjct: 407 KDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEK 466

Query: 61  SRGRSHSRSRSR-----ERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKR 115
           S  RS S S+ R     + + R  S  ++KSR RSR +++S  R     K +S   +R R
Sbjct: 467 SNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDR-R 525

Query: 116 RIRSRSRSRSRHRHRTRSRS 135
           R +S  +     +H+ +  +
Sbjct: 526 RSQSIEQESQEKQHKNKDET 545



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 43/134 (32%), Positives = 60/134 (44%), Gaps = 13/134 (9%)

Query: 73  ERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERK-RRIRSRSRSRSRHRH-- 129
           +++ ++R R+ KK     +E  +   R  ER++SRS  R    RR   RSRSRS HR   
Sbjct: 230 DQQIKTRPRKIKKD---GKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGH 286

Query: 130 ------RTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARR 183
                 R   R + R R     K  EK RR SRS+ R       R R        +  R+
Sbjct: 287 GSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRK 346

Query: 184 LERAKKLQEQREKE 197
            +R  +   +REKE
Sbjct: 347 GDRRDR-DREREKE 359


>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 290

 Score = 98.6 bits (244), Expect = 8e-21
 Identities = 58/195 (29%), Positives = 94/195 (48%), Gaps = 6/195 (3%)

Query: 12  RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRS 71
           +  + +D+  K+ +     +KE + ++ RE+    E   +R K+K R+  R R   R R 
Sbjct: 87  KTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERD 146

Query: 72  RERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRT 131
           R+ R + R R+ +K R   RE +  R R RER+K + R  ER    R R R   + R R 
Sbjct: 147 RD-REKERERQTEKDRDGQRETETERERDREREKQKERETERD---RDRQRDTEKERERQ 202

Query: 132 RSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQ 191
             R R R R    +++ E  R   R   R       R R    D +    R+ ER K+ +
Sbjct: 203 TDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRER--DRKEERKKERK 260

Query: 192 EQREKEMVEKQKQQE 206
           ++R+KE  EK+K+++
Sbjct: 261 KERKKERKEKKKEEK 275



 Score = 85.5 bits (210), Expect = 7e-17
 Identities = 55/172 (31%), Positives = 79/172 (45%), Gaps = 21/172 (12%)

Query: 9   KQGRRHESKDKSSKKHKSEE-----HNDKEHSSDKGRERLNSS----ENGEDRHKRKERK 59
           K+ R    K+K + +++  E       D+E    KGRER        E   DR K +ER+
Sbjct: 97  KRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQ 156

Query: 60  SSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRI-- 117
           + + R   R    ER  R R RE++K R   R+R + R   +ER++   R R+R+R+   
Sbjct: 157 TEKDRDGQRETETERE-RDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQT 215

Query: 118 -------RSRSRSRSRHRHRTRSRSR--TRSRSRDRKKRIEKPRRFSRSLSR 160
                  R   R   R R R R R R   R R RDRK+  +K R+  R   R
Sbjct: 216 ERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKER 267



 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 48/161 (29%), Positives = 75/161 (46%), Gaps = 10/161 (6%)

Query: 9   KQGRRHESKDKSSKKHKS-----EEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRG 63
           KQ  R   +D+  ++ +      E     E   D  RE     E   +R K+KER++ R 
Sbjct: 129 KQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERD 188

Query: 64  RSHSRSRSRERRH---RSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRER-KRRIRS 119
           R   R   +ER     R R R+RK    R RE  +   R  +R++ R R R+R K R R 
Sbjct: 189 RDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRE 248

Query: 120 RSRSRSRHRHRTRSRSRTR-SRSRDRKKRIEKPRRFSRSLS 159
           R R   R + R + R + R  + ++ K+R +K R++   +S
Sbjct: 249 RDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGEGIS 289



 Score = 78.6 bits (192), Expect = 9e-15
 Identities = 55/173 (31%), Positives = 81/173 (46%), Gaps = 12/173 (6%)

Query: 37  DKGRERLNSSENGEDRHKRKERKSSRG--RSHSRSRSRERRHRSRSRERKKSRSRSR-ER 93
           D  R RL S E+       +  K + G  R   R R RE+  + R R+RK+ R R R E+
Sbjct: 48  DFSRGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEK 107

Query: 94  KKSRSRSRERKKSRSRSRER---KRRIRSRSRSRSRHRHRTRSRSRTRSRSRDR------ 144
           + +R+R RE++    R RER   K R R R R R R R R R + R R   +DR      
Sbjct: 108 ETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRET 167

Query: 145 KKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKE 197
           +   E+ R   +   R       R R+T  + +    R  +R +K Q +R++E
Sbjct: 168 ETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRE 220


>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
          Length = 1564

 Score = 98.2 bits (243), Expect = 1e-20
 Identities = 52/143 (36%), Positives = 80/143 (55%), Gaps = 4/143 (2%)

Query: 10  QGRRHE-SKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 68
           QGR  E  +D+  ++ + +  +D+    ++ RER    E   +R + +ER+  R R   R
Sbjct: 648 QGRNDELERDERREERRVDRVDDRR--DERARERDRERERDRERERERERERDREREKER 705

Query: 69  SRSRER-RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRH 127
              RER R R R RE+++ R R R+R   R R RER++ R + RER+R  R R R R R 
Sbjct: 706 ELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERE 765

Query: 128 RHRTRSRSRTRSRSRDRKKRIEK 150
           R R R R R R+R RD+++  ++
Sbjct: 766 RERERERERERARERDKERERQR 788



 Score = 96.3 bits (238), Expect = 4e-20
 Identities = 50/143 (34%), Positives = 76/143 (53%), Gaps = 3/143 (2%)

Query: 13  RHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSR 72
           RH+ ++   ++ +  E    +   D+  ER    +   +R + +ER+  R R   R + R
Sbjct: 646 RHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKER 705

Query: 73  E-RRHRSRSRERKKSRSRSRERKKSR--SRSRERKKSRSRSRERKRRIRSRSRSRSRHRH 129
           E  R R+R RER++ + R RER + R   R RER++ R R +ER+R    R R R R R 
Sbjct: 706 ELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERE 765

Query: 130 RTRSRSRTRSRSRDRKKRIEKPR 152
           R R R R R R+R+R K  E+ R
Sbjct: 766 RERERERERERARERDKERERQR 788



 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 63/194 (32%), Positives = 93/194 (47%), Gaps = 18/194 (9%)

Query: 12  RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRH------KRKERKSSRGRS 65
           RRH  +D+   + + +  +       +  E L   E  E+R       +R ER   R R 
Sbjct: 624 RRHGERDRRDNRERDQRPSSPIRHQGRNDE-LERDERREERRVDRVDDRRDERARERDRE 682

Query: 66  HSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKR---RIRSRSR 122
             R R RER  R R R+R++ + R  ER+++R R RER+K R R R+R R   R R R R
Sbjct: 683 RERDRERERE-RERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERER 741

Query: 123 SRSRHRHRTRSR-SRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALA 181
            R R + R R R  R R R R+R++  E+ R   R+  R       + R    D ++   
Sbjct: 742 ERDREKEREREREERERERERERERERERERERERARERD------KERERQRDWEDKDK 795

Query: 182 RRLERAKKLQEQRE 195
            R +R +K +E RE
Sbjct: 796 GRDDRREKREEIRE 809



 Score = 90.1 bits (222), Expect = 3e-18
 Identities = 55/157 (35%), Positives = 76/157 (48%), Gaps = 5/157 (3%)

Query: 12  RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRS 71
           RR E +       + E   +++   ++ RER    E   DR + KER+  R R+  R R 
Sbjct: 659 RREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARERERE 718

Query: 72  RER---RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHR 128
           RE+   R R R R+  + R R RER + + R RER++ R R RER+R  R R R R R R
Sbjct: 719 REKERDRERDRDRDHDRERERERERDREKEREREREE-RERERERERE-RERERERERER 776

Query: 129 HRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPP 165
            R R + R R R  + K +    RR  R   R    P
Sbjct: 777 ARERDKERERQRDWEDKDKGRDDRREKREEIREDRNP 813



 Score = 87.4 bits (215), Expect = 2e-17
 Identities = 52/169 (30%), Positives = 84/169 (49%), Gaps = 6/169 (3%)

Query: 13  RHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSR 72
           R   +D+  ++ +  E  D+E   ++  ER  + E   +R K ++R+  R R H R R R
Sbjct: 681 RERERDRERERERERER-DREREKERELERERAREREREREKERDRERDRDRDHDRERER 739

Query: 73  ER---RHRSRSRER-KKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSR-H 127
           ER   R + R RER ++ R R RER++ R R RER+++R R +ER+R+     + + R  
Sbjct: 740 ERERDREKEREREREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDD 799

Query: 128 RHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDA 176
           R   R   R     RD     +  +R+    S +P   P R R  + D+
Sbjct: 800 RREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDS 848



 Score = 85.9 bits (211), Expect = 5e-17
 Identities = 55/193 (28%), Positives = 95/193 (49%), Gaps = 5/193 (2%)

Query: 15  ESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRER 74
           E++    ++ +  E ++++ + D   ER +   +  D  +R +R SS  R   R+   ER
Sbjct: 597 ETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELER 656

Query: 75  RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSR 134
             R    ER+  R   R  +++R R RER++ R R RER+R  R R R + R   R R+R
Sbjct: 657 DERRE--ERRVDRVDDRRDERARERDRERERDRERERERERE-RDREREKERELERERAR 713

Query: 135 SRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQR 194
            R R R ++R +  ++ R   R   R       + R    + +E   R  ER ++ + +R
Sbjct: 714 EREREREKERDRERDRDRDHDRERERERERDREKEREREREERER-ERERERERERERER 772

Query: 195 EKEMV-EKQKQQE 206
           E+E   E+ K++E
Sbjct: 773 ERERARERDKERE 785



 Score = 85.1 bits (209), Expect = 9e-17
 Identities = 53/177 (29%), Positives = 87/177 (49%), Gaps = 6/177 (3%)

Query: 12  RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGED--RHKRKERKSSRGRSHSRS 69
           R  + +D+ +++   E   D+E   ++ RER    E   +  R + +ER+  R +   R 
Sbjct: 667 RVDDRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRE 726

Query: 70  RSRERRH-RSRSRERKKSRSRSRERKKS-RSRSRERKKSRSRSRERKRRIRSRSRSRSRH 127
           R R+R H R R RER++ R + RER++  R R RER++ R R RER+R  R+R R + R 
Sbjct: 727 RDRDRDHDRERERERERDREKEREREREERERERERERERERERERERE-RARERDKERE 785

Query: 128 RHRT-RSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARR 183
           R R    + + R   R++++ I + R          S   +R   +    Q    RR
Sbjct: 786 RQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRR 842



 Score = 82.0 bits (201), Expect = 8e-16
 Identities = 62/236 (26%), Positives = 100/236 (42%), Gaps = 40/236 (16%)

Query: 9   KQGRRHESKDKSSKKHKS-EEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHS 67
           ++  R   +D+  +K +  E    +E   ++ +ER    +   D  + +ER+  R R   
Sbjct: 689 RERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKE 748

Query: 68  RSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERK---------KSRSRSRERKRRIR 118
           R R RE R R R RER++ R R RER+++R R +ER+         K R   RE++  IR
Sbjct: 749 REREREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIR 808

Query: 119 SRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRR-----------------FSRSLSRT 161
                R  H  R +S+ R R+      ++  K RR                   R LS+ 
Sbjct: 809 EDRNPRDGHDER-KSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQV 867

Query: 162 PSPPPFRG---------RNTAMDAQEALARRLERAKKLQEQREKE---MVEKQKQQ 205
             P   R          R      ++    R E +++ +EQ  KE    V+KQ++Q
Sbjct: 868 VRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQ 923



 Score = 77.8 bits (190), Expect = 1e-14
 Identities = 64/232 (27%), Positives = 102/232 (43%), Gaps = 30/232 (12%)

Query: 5   NFFLKQGRRHESKDKSSKKHKSEEHNDKEHSS--------DKGRE-----RLNSSENGED 51
           N   ++  R E +++S  + +SE  ND+   S        +KG       +++S  +  +
Sbjct: 532 NHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSN 591

Query: 52  RHKRKERKSSR----------GRSHSRSRSRERRHRSRSRERKKSRSR---SRERKKSRS 98
            H   E +SS            R  +R  S ERRH  R R   + R +   S  R + R+
Sbjct: 592 YHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRN 651

Query: 99  RSRERKKSRSRSR----ERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRF 154
              ER + R   R    + +R  R+R R R R R R R R R R R R+R+K  E  R  
Sbjct: 652 DELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERER 711

Query: 155 SRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQE 206
           +R   R       R R+   D      R  ER ++ + +RE+E  E+++++E
Sbjct: 712 AREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERE 763



 Score = 62.0 bits (149), Expect = 8e-10
 Identities = 56/209 (26%), Positives = 94/209 (44%), Gaps = 22/209 (10%)

Query: 15  ESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRER 74
           E +D S    +S +  D   + D    R      G D H++++      RS+ R+  RE 
Sbjct: 481 EMRDYSRDTKESRDPRDSRSTRDAHDYR---DREGRDTHRKEDTYPEESRSYGRNHLREE 537

Query: 75  RHRS--RSRERKKSRSRSRERKKSRSRSRERKKSRSRSR-ERKRRIRSRS---------R 122
             R+  R+  R +SRS  R  +  RSR R  +     SR  R  +I S S          
Sbjct: 538 SSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWE 597

Query: 123 SRSRHRHRTRSRSR-TRSRSRD---RKKRIEKPRRFSRSLSRTPSPP-PFRGRNTAMDAQ 177
           +RS +  R R   R  R ++RD    ++  E+ RR +R   + PS P   +GRN  ++  
Sbjct: 598 TRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERD 657

Query: 178 EALARRLERAKKLQEQREKEMVEKQKQQE 206
           E   R   R  ++ ++R++   E+ +++E
Sbjct: 658 E--RREERRVDRVDDRRDERARERDRERE 684



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 65/207 (31%), Positives = 94/207 (45%), Gaps = 17/207 (8%)

Query: 3    RTNFFLKQGRRHESKDKSSKKHKSEEHNDKE--HSSDKGRERLNSSE-NGE-----DRHK 54
            R+N     GR     + S+ +   ++   K   HS  + RE+  S E  GE     D+ K
Sbjct: 1196 RSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLK 1255

Query: 55   RKE--RKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKK-SRSRSR 111
            R E  R +S  R  SRS S  RR    S  +  SRS S +   SR R +ER +    R R
Sbjct: 1256 RGEPSRSTSSDRQDSRSHS-SRRSSPESDRQVHSRSGSFD---SRDRLQERDRYEHDRER 1311

Query: 112  ERKRR-IRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGR 170
            ER+RR  R R   R   +   R+R R R R R+R++  +K R   R   R  S    R R
Sbjct: 1312 ERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVERDR 1371

Query: 171  NTAMDAQEALARRLERAKKLQEQREKE 197
            +   D +   + ++E  K+ + + E E
Sbjct: 1372 DRDRD-RTFESSQIESVKRCEAKLEGE 1397



 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 45/167 (26%), Positives = 69/167 (41%), Gaps = 3/167 (1%)

Query: 31   DKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRS 90
            D++ SS  G  R N S             + R       R R     SR RE+ KS   +
Sbjct: 1185 DQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEIT 1244

Query: 91   RERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEK 150
             ERK    + +  + SRS S +R+    SRS S  R    +  +  +RS S D + R+++
Sbjct: 1245 GERKSRIDQLKRGEPSRSTSSDRQ---DSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQE 1301

Query: 151  PRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKE 197
              R+     R       R R    DA +   R  +R +  + +RE+E
Sbjct: 1302 RDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERE 1348



 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 54/205 (26%), Positives = 84/205 (40%), Gaps = 22/205 (10%)

Query: 8    LKQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSS--ENGEDRHKRKERKSSRGRS 65
            ++  +  +  D+          +++ H+S + R   N S   +G+D+  RK    S  R 
Sbjct: 1175 IEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRD 1234

Query: 66   HSRSRSRERRHRSRSR-----ERKKSRSRSRERKKSRSRSRERKK--------SRSRSRE 112
              +++S E     +SR       + SRS S +R+ SRS S  R          SRS S +
Sbjct: 1235 REKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFD 1294

Query: 113  RKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNT 172
             + R++ R R     R R R R  TR R  DR    + PR   R   R       R R  
Sbjct: 1295 SRDRLQERDR-YEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRE------RERER 1347

Query: 173  AMDAQEALARRLERAKKLQEQREKE 197
              D +  L R  ER      +R+++
Sbjct: 1348 ERDKRRDLDRERERLISDSVERDRD 1372



 Score = 55.8 bits (133), Expect = 6e-08
 Identities = 44/161 (27%), Positives = 66/161 (40%), Gaps = 16/161 (9%)

Query: 12  RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSE--NGEDRHKRKERKSSRGRSHSRS 69
           RR +++ K  ++  S E  + E      R+  +  E  +G DR   ++ +  R    SR 
Sbjct: 416 RREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRD 475

Query: 70  RSRERRHRSRSRERKKSRS-------------RSRE-RKKSRSRSRERKKSRSRSRERKR 115
               R  R  SR+ K+SR              R RE R   R      ++SRS  R   R
Sbjct: 476 MRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLR 535

Query: 116 RIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSR 156
              SR+  R+  R+ +RS  R     R R +  E P + SR
Sbjct: 536 EESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSR 576



 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 54/185 (29%), Positives = 80/185 (43%), Gaps = 35/185 (18%)

Query: 13  RHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHK--RKERKSSRGRSHSRSR 70
           RH S  +   +H   +H     S D+  ER   +    DR K  R+ER+  + +S SR  
Sbjct: 390 RHRSPMREKGRH---DHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDH 446

Query: 71  --------SRERRHRSRSRERKKSRSR--SRERKKSRSRSRERKKSR----SRS------ 110
                    R+RR    +R+R++ R     R+ ++ R  SR+ K+SR    SRS      
Sbjct: 447 RDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHD 506

Query: 111 -RERKRRIRSR--------SRSRSR-HRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSR 160
            R+R+ R   R        SRS  R H     SR+  R+ SR+  +   +  R  RS  R
Sbjct: 507 YRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGR 566

Query: 161 TPSPP 165
            P  P
Sbjct: 567 VPELP 571



 Score = 52.4 bits (124), Expect = 7e-07
 Identities = 55/237 (23%), Positives = 90/237 (37%), Gaps = 46/237 (19%)

Query: 11  GRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGR---SHS 67
           GR H  ++ S  + ++E  N  E  S+   +R+  S         K  + SRG    SHS
Sbjct: 530 GRNHLREESSRTEIRNESRN--ESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHS 587

Query: 68  RSRSRERRHRSRSRERKKSRSRSRE-RKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSR 126
            + +      +RS   ++ R   R+ R ++R  S ER+      R+ + R +   R  S 
Sbjct: 588 SNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQ---RPSSP 644

Query: 127 HRH-------------------------------------RTRSRSRTRSRSRDRKKRIE 149
            RH                                     R R R R R R RDR++  E
Sbjct: 645 IRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKE 704

Query: 150 KPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQE 206
           +     R+  R       R R    D      R  ER +  +++RE+E  E+++++E
Sbjct: 705 RELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERE 761



 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 50/198 (25%), Positives = 80/198 (40%), Gaps = 28/198 (14%)

Query: 10  QGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGE--DRHK---RKERKSSRGR 64
           +GR  E + +   K +S     + HS    R   +SS++G    RH    R++R  S   
Sbjct: 300 RGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSY 359

Query: 65  SHS------RSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIR 118
             +      RS S    H   S +RK+S  R R   + + R    + S+S  R  +RR  
Sbjct: 360 QRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERRED 419

Query: 119 SR-SRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQ 177
           +R  R R +     R   + +S SRD +   E              P   R R  A D +
Sbjct: 420 TRGKRDREKDSREEREYEQDQSSSRDHRDDRE--------------PRDGRDRRDARDTR 465

Query: 178 EALARRLERAKKLQEQRE 195
           +   R L  ++ +++ RE
Sbjct: 466 D--RRELRDSRDMRDSRE 481



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 40/142 (28%), Positives = 63/142 (44%), Gaps = 10/142 (7%)

Query: 14  HESKDKSSKKHKSEEHNDKEHSSDKGR-ERLNSSENGEDRHKRKERKSSRGRSHSRSRSR 72
           + S   SS + K      +    +KGR +   +S++ + RH+R+E   +RG+      SR
Sbjct: 374 YPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERRE--DTRGKRDREKDSR 431

Query: 73  ERRHRSRSRERKKSRSRSRERKKSRSR-----SRERKKSR-SRSRERKRRIRSRSRSRSR 126
           E R   + +   +     RE +  R R     +R+R++ R SR     R +R  SR    
Sbjct: 432 EEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKE 491

Query: 127 HRHRTRSRS-RTRSRSRDRKKR 147
            R    SRS R     RDR+ R
Sbjct: 492 SRDPRDSRSTRDAHDYRDREGR 513



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 35/126 (27%), Positives = 50/126 (39%), Gaps = 5/126 (3%)

Query: 52  RHKRKERKSSRGRSHSRSRSRERRHRSRS-----RERKKSRSRSRERKKSRSRSRERKKS 106
           RH+   R+  R      S+S +RRH  R      R+R+K     RE ++ +S SR+ +  
Sbjct: 390 RHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDD 449

Query: 107 RSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPP 166
           R     R RR    +R R   R     R     R   R  +  +  R SRS         
Sbjct: 450 REPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRD 509

Query: 167 FRGRNT 172
             GR+T
Sbjct: 510 REGRDT 515



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 49/253 (19%), Positives = 89/253 (35%), Gaps = 52/253 (20%)

Query: 9    KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLN------SSENGEDRHKRKERKSSR 62
            ++  R  ++++  ++ +  +  DK+   D  RE+        +  +G D  K K+R  + 
Sbjct: 770  RERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNE 829

Query: 63   GRSHSRSRSRERRHRSRSRERKKSRSRSRER----------KKSRSRS--------RERK 104
            G    R   + RR  S   +   S     E+          ++SRS S        + R 
Sbjct: 830  GSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRW 889

Query: 105  KSRSRSRERKRRIR--------------------------SRSRSRSRHRHRTRSRSRTR 138
            K   R  ERK   R                          SR R++    H       T 
Sbjct: 890  KEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETS 949

Query: 139  SRSRDRKKRIEKPRRFSRSLSRTPSPPPFRG--RNTAMDAQEALARRLERAKKLQEQREK 196
             R+ D  K+  K ++      +       RG    T+ D Q    ++ ++ K ++++R+K
Sbjct: 950  DRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKK 1009

Query: 197  EMVEKQKQQEIAA 209
               +     E AA
Sbjct: 1010 SKGDSDISDEEAA 1022



 Score = 37.4 bits (85), Expect = 0.022
 Identities = 41/199 (20%), Positives = 77/199 (38%), Gaps = 18/199 (9%)

Query: 10  QGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRS 69
           +GR  E +D    K ++ E  ++    +  R+  ++ +   D       +  R +     
Sbjct: 118 RGRHREKEDIKITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQREL 177

Query: 70  RSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRH 129
              E+ +  +  E    +  S E  +S+       +  S+S +RK   +S S S+     
Sbjct: 178 MKLEQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASK----- 232

Query: 130 RTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPP-----------FRGRNTAMDAQE 178
           + R  S   S   D+++   K  +  +   RTPSPPP           ++ +    D  E
Sbjct: 233 KDRKTSAVSSPLLDQQRN-SKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIE 291

Query: 179 ALAR-RLERAKKLQEQREK 196
              R   +R +  + QREK
Sbjct: 292 EKTRDGKDRGRDFERQREK 310



 Score = 37.0 bits (84), Expect = 0.029
 Identities = 25/108 (23%), Positives = 44/108 (40%), Gaps = 6/108 (5%)

Query: 12   RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGR------S 65
            R  E + + +++ + +   DK+   ++ R+RL   E   +R KR++    R R       
Sbjct: 1309 RERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVE 1368

Query: 66   HSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRER 113
              R R R+R   S   E  K      E +  R      + S +  +ER
Sbjct: 1369 RDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTSRDSLALDKER 1416



 Score = 35.4 bits (80), Expect = 0.084
 Identities = 28/144 (19%), Positives = 61/144 (42%), Gaps = 33/144 (22%)

Query: 9    KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDR------HKRKERKSSR 62
            K+  R   + +SS++++ +E  +K  S DK RE+    E+   R      H + E + + 
Sbjct: 890  KEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETS 949

Query: 63   GRSHSRSRSRERRHRSRSRERK---------------------------KSRSRSRERKK 95
             R+H  ++ + +  +   +++K                           K +S  ++RKK
Sbjct: 950  DRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKK 1009

Query: 96   SRSRSRERKKSRSRSRERKRRIRS 119
            S+  S    +  ++  ++KR  R+
Sbjct: 1010 SKGDSDISDEEAAQQSKKKRGPRT 1033



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 21/89 (23%), Positives = 36/89 (40%), Gaps = 1/89 (1%)

Query: 9    KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 68
            K   R+  +D+  ++ +  E  DK    D+ RERL S     DR + ++R     +  S 
Sbjct: 1329 KDWPRNRDRDRLRERERERER-DKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESV 1387

Query: 69   SRSRERRHRSRSRERKKSRSRSRERKKSR 97
             R   +      R+ + +   S    K R
Sbjct: 1388 KRCEAKLEGEHERDLESTSRDSLALDKER 1416


>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
          Length = 494

 Score = 97.4 bits (241), Expect = 2e-20
 Identities = 65/209 (31%), Positives = 112/209 (53%), Gaps = 7/209 (3%)

Query: 10  QGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRS 69
           +GR++E   +       +   +K   ++    ++   E+     +R+    SR  S SRS
Sbjct: 137 KGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRS 196

Query: 70  RSR-ERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHR 128
           RSR  R+ RSRS   K S S+SR R +S SRSR + +SRS+SR R ++ +SRS S+ + R
Sbjct: 197 RSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSR 256

Query: 129 HRTRSRSRTRSRSRDR-KKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERA 187
            R+ S  ++RS+S+D+ +++I+      +  SR+PS    R ++ +     +  RR+E  
Sbjct: 257 SRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPS----RHKSKSKSRSRSQERRVEEE 312

Query: 188 KKLQEQREKEMVEKQKQQEIAAAAATGGS 216
           K+    R +   EK  +Q  + + + GGS
Sbjct: 313 KRGSVSRGRSQ-EKSLRQSRSRSRSKGGS 340



 Score = 97.4 bits (241), Expect = 2e-20
 Identities = 63/189 (33%), Positives = 95/189 (50%), Gaps = 7/189 (3%)

Query: 13  RHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSS-----ENGEDRHKRKERKSSRGRSHS 67
           R  SK + S+    E+   + HS+ K R +         +N ++  K K R  SR +S S
Sbjct: 239 RSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKS 298

Query: 68  RSRSRERRHRSRSRERKK-SRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSR 126
           +SRSR +  R    +R   SR RS+E+   +SRSR R K  SRSR R R  +S+ + + R
Sbjct: 299 KSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRS-KSKDKRKGR 357

Query: 127 HRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLER 186
            R R  SRSR+RSRS+  + R    +R S++ S          R+ +     ++++  E 
Sbjct: 358 KRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREH 417

Query: 187 AKKLQEQRE 195
           AK    QRE
Sbjct: 418 AKSESSQRE 426



 Score = 96.3 bits (238), Expect = 4e-20
 Identities = 72/232 (31%), Positives = 113/232 (48%), Gaps = 38/232 (16%)

Query: 9   KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 68
           K G R       S+ H S   +   HS  K R R  SS++   + + + R  SR RS SR
Sbjct: 176 KPGSRRRRSYSRSRSH-SRSRSRSRHSR-KSRSRSGSSKSSHSKSRSRSRSGSRSRSKSR 233

Query: 69  SRS----RERRHRSRSRERKKSRSRSRERKKSRSRS-----------------------R 101
           SRS    R ++ +SRS  ++KSRSRS    KSRS+S                       R
Sbjct: 234 SRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSR 293

Query: 102 ERKKSRSRSRERKRRI---------RSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPR 152
            + KS+SRSR ++RR+         R RS+ +S  + R+RSRS+  SRSR R +   K +
Sbjct: 294 HKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDK 353

Query: 153 RFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQ 204
           R  R  SR  S    R R+ +  +++  ++R  +A   +++++++    Q +
Sbjct: 354 RKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSR 405



 Score = 91.7 bits (226), Expect = 1e-18
 Identities = 71/219 (32%), Positives = 112/219 (51%), Gaps = 20/219 (9%)

Query: 17  KDKSSKKHKSEEHNDKEHSSDKGRERLN-SSENGEDRHKRKERKS-SRGRSHSRSRSRER 74
           +DK   + +      + HS  + R R +  S +     K    KS SR RS SRSRS+ R
Sbjct: 174 EDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSR 233

Query: 75  -RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRER-KRRIRS-------RSRSRS 125
            R +SRSR  KK +SRS  ++KSRSRS    KSRS+S+++ + +I++       +SRS S
Sbjct: 234 SRSQSRSRS-KKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPS 292

Query: 126 RHRHRTRSRSRTRSRSRDRKKR--------IEKPRRFSRSLSRTPSPPPFRGRNTAMDAQ 177
           RH+ +++SRSR++ R  + +KR         EK  R SRS SR+      R R+ +    
Sbjct: 293 RHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKD 352

Query: 178 EALARRLERAKKLQEQREKEMVEKQKQQEIAAAAATGGS 216
           +   R+  R +     R +   E+ +++     +  G S
Sbjct: 353 KRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSS 391



 Score = 91.3 bits (225), Expect = 1e-18
 Identities = 64/184 (34%), Positives = 92/184 (50%), Gaps = 21/184 (11%)

Query: 9   KQGRRHESKDKSSKKHKSEEHN---DKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRS 65
           ++ R  E K  S  + +S+E +    +  S  KG  R  S    + + KRK RK SR  S
Sbjct: 305 QERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREES 364

Query: 66  HSRSRSRERRHRSRSR-------------ERKKSRSRSRERKKSRSRSRERKKSRSRSRE 112
            SRSRSR +  RSR R             ++K+   RS+ R  SRS S+ER+ ++S S +
Sbjct: 365 RSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQ 424

Query: 113 RKRRIRSRS-----RSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPF 167
           R+ R  S +      +RSR R  ++S+    S SR R K   K R  S+S SR+ S  P 
Sbjct: 425 REGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPS 484

Query: 168 RGRN 171
           R R+
Sbjct: 485 RSRS 488



 Score = 86.3 bits (212), Expect = 4e-17
 Identities = 60/186 (32%), Positives = 94/186 (50%), Gaps = 11/186 (5%)

Query: 13  RHESKDKS-SKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRS 71
           RH+SK KS S+  +     +K  S  +GR +  S      R + K    SR RS S+S+ 
Sbjct: 293 RHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKD 352

Query: 72  RERRHRSRSRERKKSRSRSRER-KKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHR 130
           + R+ R RSRE  +SRSRSR + ++SR R  +R      S+++K+    RS+SRS  R  
Sbjct: 353 K-RKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSV 411

Query: 131 TRSRSRTRSRSRDRKKRIE--------KPRRFSRSLSRTPSPPPFRGRNTAMDAQEALAR 182
           ++ R   +S S  R+ R E        + R  SRS S++    P   R+ +  A +  +R
Sbjct: 412 SKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSR 471

Query: 183 RLERAK 188
              R++
Sbjct: 472 SKSRSR 477


>gi|116812577 LUC7-like 2 [Homo sapiens]
          Length = 392

 Score = 95.5 bits (236), Expect = 7e-20
 Identities = 59/155 (38%), Positives = 87/155 (56%), Gaps = 9/155 (5%)

Query: 54  KRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRER 113
           KR   +    R+  R + RE R R    + ++SRS S+  K+SRSR   R +SRS SRER
Sbjct: 229 KRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRER 288

Query: 114 KRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTA 173
           KRR RS+SR + RHRHR+RS SR+RSRS  R +   + R   RS  R  S   FR ++ A
Sbjct: 289 KRRTRSKSREK-RHRHRSRSSSRSRSRSHQRSRHSSRDRSRERS-KRRSSKERFRDQDLA 346

Query: 174 MDAQEALARRLERAKKLQEQREKEMVEKQKQQEIA 208
              +       +R+ + +  R+++  +K++  E A
Sbjct: 347 SCDR-------DRSSRDRSPRDRDRKDKKRSYESA 374



 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 62/167 (37%), Positives = 86/167 (51%), Gaps = 9/167 (5%)

Query: 33  EHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRE 92
           E    + +ERL   +  E+R + +  K  R RSHS++    +R RSR   R +SRS SRE
Sbjct: 234 EKQEKRNQERL---KRREEREREEREKLRRSRSHSKN---PKRSRSREHRRHRSRSMSRE 287

Query: 93  RKK-SRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKP 151
           RK+ +RS+SRE K+ R RSR   R  RSRS  RSRH  R RSR R++ RS   + R +  
Sbjct: 288 RKRRTRSKSRE-KRHRHRSRSSSRS-RSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDL 345

Query: 152 RRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEM 198
               R  S     P  R R     + E+   R E  +  +E+   E+
Sbjct: 346 ASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEEREAGEI 392



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 57/148 (38%), Positives = 76/148 (51%), Gaps = 8/148 (5%)

Query: 19  KSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKR-KERKSSRGRSHSRSRSRERRHR 77
           +  +K   E    +E    + RE+L  S +     KR + R+  R RS S SR R+RR R
Sbjct: 234 EKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTR 293

Query: 78  SRSRE-RKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHR---HRTRS 133
           S+SRE R + RSRS  R +SRS  R R  SR RSRER +R  S+ R R +      R RS
Sbjct: 294 SKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRS 353

Query: 134 RSRTRSRSRDRKKRIEKPRRFSRSLSRT 161
                 R RDRK   +K R +  +  R+
Sbjct: 354 SRDRSPRDRDRK---DKKRSYESANGRS 378



 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 49/139 (35%), Positives = 70/139 (50%), Gaps = 4/139 (2%)

Query: 9   KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 68
           KQ +R++ + K  ++ + EE      S    +    S      RH+ +     R R  +R
Sbjct: 235 KQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKR-RTR 293

Query: 69  SRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHR 128
           S+SRE+RHR RSR    SRSRSR  ++SR  SR+R + RS+ R  K R R +  +     
Sbjct: 294 SKSREKRHRHRSRS--SSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRD 351

Query: 129 HRTRSRSRTRSRSRDRKKR 147
             +R RS  R R R  KKR
Sbjct: 352 RSSRDRS-PRDRDRKDKKR 369



 Score = 70.5 bits (171), Expect = 2e-12
 Identities = 50/140 (35%), Positives = 65/140 (46%), Gaps = 12/140 (8%)

Query: 12  RRHESKDKSSKKHKSEEHN-DKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSR 70
           RR  S  K+ K+ +S EH   +  S  + R+R   S++ E RH        R RS S SR
Sbjct: 259 RRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKRH--------RHRSRSSSR 310

Query: 71  SRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHR 130
           SR R H+   R R  SR RSRER K RS     +     S +R R  R RS      + +
Sbjct: 311 SRSRSHQ---RSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDRSPRDRDRKDK 367

Query: 131 TRSRSRTRSRSRDRKKRIEK 150
            RS      RS DR+   E+
Sbjct: 368 KRSYESANGRSEDRRSSEER 387



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 42/123 (34%), Positives = 64/123 (52%), Gaps = 2/123 (1%)

Query: 72  RERRHRSRSRERKKSRSRSRERKKSRS-RSRERKKSRSRSRERKRRIRSRSRSRSRHRHR 130
           RE+    +    +K   R++ER K R  R RE ++   RSR   +  + RSRSR   RHR
Sbjct: 222 REKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPK-RSRSREHRRHR 280

Query: 131 TRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKL 190
           +RS SR R R    K R ++ R  SRS SR+ S    R R+++ D     ++R    ++ 
Sbjct: 281 SRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERF 340

Query: 191 QEQ 193
           ++Q
Sbjct: 341 RDQ 343


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 95.1 bits (235), Expect = 9e-20
 Identities = 77/250 (30%), Positives = 120/250 (48%), Gaps = 32/250 (12%)

Query: 10  QGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRS 69
           + R  + + +S    +   H+    +  + R R   +  G  R +   R+ SR R+ +R 
Sbjct: 544 RSRNTQRRGRSRSARRGRSHSRSPATRGRSRSR-TPARRGRSRSRTPARRRSRSRTPTRR 602

Query: 70  RSRER------RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRS 123
           RSR R      R RSR+  R++SR+RS  R++SRSRS  R+  RSRSR   RR RSRSR+
Sbjct: 603 RSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRT 662

Query: 124 RSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTP------------------SPP 165
            +R   R RSRSRT +R R  + R   P R  RS SRTP                    P
Sbjct: 663 PAR---RGRSRSRTPAR-RSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTP 718

Query: 166 PFRGRNTAMDAQEALARRLERAKKLQEQRE--KEMVEKQKQQEIAAAAATGGSVLNVAAL 223
             RGR+ +   ++  +R  +R  +     E  K  +  ++ + +++  +   S L++   
Sbjct: 719 QRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRS 778

Query: 224 LASGTQVTPQ 233
           L SG+   P+
Sbjct: 779 L-SGSSPCPK 787



 Score = 89.0 bits (219), Expect = 6e-18
 Identities = 67/174 (38%), Positives = 90/174 (51%), Gaps = 14/174 (8%)

Query: 10  QGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERL-NSSENGEDRHKRKERKSSR-----G 63
           Q RR  S  +  +    +           G  R  N+   G  R  R+ R  SR     G
Sbjct: 512 QWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRG 571

Query: 64  RSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRS 123
           RS SR+ +R  R RSR+  R++SRSR+  R++SRSR+  R + RSRSR   RR RSR+RS
Sbjct: 572 RSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPAR-RGRSRSRTPARR-RSRTRS 629

Query: 124 RSRHRHRTRS------RSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRN 171
             R R R+RS      RSR+R+ +R  + R   P R  RS SRTP+    R R+
Sbjct: 630 PVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRS 683



 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 75/242 (30%), Positives = 115/242 (47%), Gaps = 26/242 (10%)

Query: 16  SKDKS---SKKHKSEEHNDKEH--------SSDKGRERLNS-SENGEDRHKRKE-RKSSR 62
           SK++S   +K+ KS  H             ++ +GR R  + ++ G  R +  + R+S  
Sbjct: 459 SKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRS 518

Query: 63  GRSHSRSRSRERRHRSRSRER----------KKSRSRSRERKKSRSRSRERKKSRSRSRE 112
            +   RSRS +RR RSRS +R          ++ RSRS  R +S SRS    + RSRSR 
Sbjct: 519 AQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRS-PATRGRSRSRT 577

Query: 113 RKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKR-IEKPRRFSRSLSRTPSPPPFRGRN 171
             RR RSRSR+ +R R R+R+ +R RSRSR   +R   + R  +R  SRT SP   R R+
Sbjct: 578 PARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRS 637

Query: 172 TAMDAQEALARRLERAKKLQEQREKEMVEKQKQQEIAAAAATGGSVLNVAALLASGTQVT 231
            +   +   +R    A++    R +    + + +    A  +G S     A        T
Sbjct: 638 RSPARRSGRSRSRTPARR-GRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRT 696

Query: 232 PQ 233
           P+
Sbjct: 697 PR 698



 Score = 78.6 bits (192), Expect = 9e-15
 Identities = 64/180 (35%), Positives = 84/180 (46%), Gaps = 21/180 (11%)

Query: 12  RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRS 71
           R   S   S  +       DK HS    R    S      +  R   ++   R HSRSRS
Sbjct: 451 REISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRS 510

Query: 72  RERRHRSRSRER--------KKSRSRSRER--------KKSRSRSRERKKSRSRSRERKR 115
            + R RSRS +R        ++ RSRS +R         + R RSR  ++ RS SR    
Sbjct: 511 PQWR-RSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPAT 569

Query: 116 RIRSRSRS---RSRHRHRTRSRSRTRSRSRDRKK-RIEKPRRFSRSLSRTPSPPPFRGRN 171
           R RSRSR+   R R R RT +R R+RSR+  R++ R   P R  RS SRTP+    R R+
Sbjct: 570 RGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRS 629



 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 73/208 (35%), Positives = 91/208 (43%), Gaps = 27/208 (12%)

Query: 13  RHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSR 72
           RH S    S K      + +E SS    +  N S     R K      SR    SRS + 
Sbjct: 432 RHASSSPESPKPAPAPGSHREISSSPTSK--NRSHGRAKRDKSHSHTPSRRMGRSRSPAT 489

Query: 73  ERRHRSRSR---ERKKSRSRSRERKKSRS------------RSRERKKSR---SRSRERK 114
            +R RSRSR   +R  SRSRS + ++SRS            R R R   R   SRSR  +
Sbjct: 490 AKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQ 549

Query: 115 RRIRSRSRSRSRHRHR---TRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRN 171
           RR RSRS  R R   R   TR RSR+R+ +R  + R   P R  RS SRTP+    R R 
Sbjct: 550 RRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPAR-RRSRSRTPTRRRSRSRT 608

Query: 172 TA---MDAQEALARRLERAKKLQEQREK 196
            A          ARR  R +    +R +
Sbjct: 609 PARRGRSRSRTPARRRSRTRSPVRRRSR 636



 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 77/236 (32%), Positives = 103/236 (43%), Gaps = 46/236 (19%)

Query: 3    RTNFFLKQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSS- 61
            RT    ++GR    K +  ++ +S    +K  ++ + R+R  SS++   R +R   +S  
Sbjct: 1752 RTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRR-RDRSGSSQSTSRRRQRSRSRSRV 1810

Query: 62   ----RGRS--HSRSRSRE-------RRHRSRSRERKKSRSRSRER------KKSRSR--- 99
                RG S  HSRS +R+       RR R RSR    SR RSR R      K+SRSR   
Sbjct: 1811 TRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASP 1870

Query: 100  -----------------SRERKK--SRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSR 140
                             SR R    SR RSR R    R RSRSR+    R RSRSRT   
Sbjct: 1871 ATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPV 1930

Query: 141  SRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREK 196
            +R R+ R   P    RS SRT  PP  R R+ +        R   R   +  +R +
Sbjct: 1931 TR-RRSRSRTPTTRRRSRSRT--PPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSR 1983



 Score = 72.0 bits (175), Expect = 8e-13
 Identities = 61/210 (29%), Positives = 88/210 (41%), Gaps = 19/210 (9%)

Query: 15   ESKDKSSKKHK------SEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 68
            E++ ++  +H+      S E  +K  SS + R   +       R  R      RG   SR
Sbjct: 1715 ETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSR 1774

Query: 69   SRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSR------SRERKRRIRSRSR 122
            SRSR  + R+  R  +   S+S  R++ RSRSR R   R R      SR   R+  SR+ 
Sbjct: 1775 SRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTS 1834

Query: 123  SRSRH-RHRTRSRSRTRSRSR------DRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMD 175
            SR R  R RT   SR RSRSR       R +    P    RS SRTP     R R+    
Sbjct: 1835 SRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSP 1894

Query: 176  AQEALARRLERAKKLQEQREKEMVEKQKQQ 205
                 +R      + + +     V +++ +
Sbjct: 1895 VSRRRSRSRTSVTRRRSRSRASPVSRRRSR 1924



 Score = 70.1 bits (170), Expect = 3e-12
 Identities = 79/294 (26%), Positives = 122/294 (41%), Gaps = 45/294 (15%)

Query: 3    RTNFFLKQGRRH----ESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKER 58
            RT+   ++GR        K   S+   +     +  +S     R  S      R + + R
Sbjct: 1832 RTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSR 1891

Query: 59   KSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRER------KKSRSR---SRERKKSRS- 108
             S   R  SRSR+   R RSRSR    SR RSR R      ++SRSR   +R R +SR+ 
Sbjct: 1892 TSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTP 1951

Query: 109  -----RSRER-----KRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFS--- 155
                 RSR R     +RR RSR+   +R R R+R+   TR RSR R   + + R  S   
Sbjct: 1952 PVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTS 2011

Query: 156  -----RSLSRTP--------SPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEK- 201
                 RS SRTP        S  P   R  +        RR  R++  +  R K  + + 
Sbjct: 2012 PVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRS 2071

Query: 202  ----QKQQEIAAAAATGGSVLNVAALLASGTQVTPQIAMAAQMAALQAKALAET 251
                +++    +++    S    A    SG++  P    +++M+     +++ T
Sbjct: 2072 PPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPT 2125



 Score = 69.7 bits (169), Expect = 4e-12
 Identities = 61/184 (33%), Positives = 88/184 (47%), Gaps = 10/184 (5%)

Query: 17   KDKSSKKHKSEEHNDKEHSSDKGRERLNSSENG-EDRHKRKERKSSRGRSHSRSRSRERR 75
            K + S++ +S   + +  S    R R + S +  E   K +  +  R  S  R+++  RR
Sbjct: 1700 KARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRR 1759

Query: 76   HRSRS---RERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTR 132
             RS S   R  ++SRSRSR  K   +R R+R  S S+S  R+R+ RSRSRSR   R R  
Sbjct: 1760 GRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGS-SQSTSRRRQ-RSRSRSRVTRRRRGG 1817

Query: 133  SRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQE 192
            S   +RS +R    R    RR  R  SRT  PP  R R+ +  +     R   RA     
Sbjct: 1818 SGYHSRSPARQESSRTSSRRR--RGRSRT--PPTSRKRSRSRTSPAPWKRSRSRASPATH 1873

Query: 193  QREK 196
            +R +
Sbjct: 1874 RRSR 1877



 Score = 69.3 bits (168), Expect = 5e-12
 Identities = 64/200 (32%), Positives = 94/200 (47%), Gaps = 23/200 (11%)

Query: 13   RHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSH----SR 68
            R ES   SS++ +         S  + R R + +     R +       R RS     SR
Sbjct: 1827 RQESSRTSSRRRRGRSRTPPT-SRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISR 1885

Query: 69   SRSRER-----RHRSRSRE---RKKSRSRSR--ERKKSRSRSR--ERKKSRSRSRERKRR 116
             RSR R     R RSRSR    R++SRSR+    R++SRSR+    R++SRSR+   +RR
Sbjct: 1886 RRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRR 1945

Query: 117  IRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDA 176
             RSR+   +R R R+R+   TR RSR R   I + R      SR+ + P  R R+ +  +
Sbjct: 1946 SRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRR------SRSRTSPVTRRRSRSRTS 1999

Query: 177  QEALARRLERAKKLQEQREK 196
                 R   R   +  +R +
Sbjct: 2000 PVTRRRSRSRTSPVTRRRSR 2019



 Score = 65.9 bits (159), Expect = 6e-11
 Identities = 58/197 (29%), Positives = 87/197 (44%), Gaps = 32/197 (16%)

Query: 9   KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 68
           ++ R      + S+       + +  S    R   + S     R + + R  +R    SR
Sbjct: 623 RRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSR 682

Query: 69  SRSRERRHRSRSRERKKSRSRSR---ERKKSRSRSRERKKSRSRSRERKRRIR-SRSRSR 124
           SR+  RR RSRSR  ++ RSRSR    R +S SR+ +R+     S ERK + R S+ RSR
Sbjct: 683 SRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSR 742

Query: 125 SR----------HRHRTRSRSRTRSRSRDR--------------KKRIEKPRRFSRSLSR 160
           S              R+RS S  RS+++ R              K++ + P R SRS S 
Sbjct: 743 SNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSS 802

Query: 161 TPS----PPPFRGRNTA 173
            P      PP R R+++
Sbjct: 803 QPKAKSRTPPRRSRSSS 819



 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 33/121 (27%), Positives = 59/121 (48%)

Query: 44  NSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRER 103
           +SS +   + K+K++K  RGR    S  R  R +S  +++ +S S S++RK      + +
Sbjct: 178 SSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSK 237

Query: 104 KKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPS 163
           +KS+ + R+R R      +SR  HR  +   + +   SR R +        +    R+PS
Sbjct: 238 RKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPS 297

Query: 164 P 164
           P
Sbjct: 298 P 298



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 59/208 (28%), Positives = 93/208 (44%), Gaps = 22/208 (10%)

Query: 12  RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRS 71
           RR  S+ ++  +      +     + +GR R  +   G  R +   R   RGRSHSR+  
Sbjct: 665 RRGRSRSRTPARRSGRSRS--RTPARRGRSRSRTPRRGRSRSRSLVR---RGRSHSRTPQ 719

Query: 72  R--------ERRHRSRSRERKKSRSRSRERKKSR-----SRSRERKKSRSRSRERKRRIR 118
           R        ER+++SR+ +R+   + S E KKSR     SRS    +S+++SR   RR  
Sbjct: 720 RRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSL 779

Query: 119 SRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQE 178
           S S    + + +T  R R+RS S   K +   P R SRS S   SPPP +   T      
Sbjct: 780 SGSSPCPKQKSQTPPR-RSRSGSSQPKAKSRTPPRRSRSSS---SPPPKQKSKTPSRQSH 835

Query: 179 ALARRLERAKKLQEQREKEMVEKQKQQE 206
           + +    + K     R+  +   Q  ++
Sbjct: 836 SSSSPHPKVKSGTPPRQGSITSPQANEQ 863



 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 62/211 (29%), Positives = 90/211 (42%), Gaps = 26/211 (12%)

Query: 10   QGRRHESKDKSSKKHKSEEHNDKEHSSDKGR---ERLNSSENGEDRHKRKERKSSRGRSH 66
            Q     S +  +   ++     +  SS KGR      +SS      H  K R + RG   
Sbjct: 1615 QSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRS 1674

Query: 67   S-----RSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRS 121
            S     +SR+  RR  SRS      ++R   R +S S S E   +RSR+  R RR  S S
Sbjct: 1675 SPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPE---TRSRTPPRHRRSPSVS 1731

Query: 122  ------RSRSRHRHRTRSRSRTRSRSRDRKKRIEKPR--RFSRSLSRTPSPPPFRGRNTA 173
                  +SRS  R R+ S  RT++ SR  +    KPR  + SRS SR       R R+ +
Sbjct: 1732 SPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRS 1791

Query: 174  MDAQEALARRLERAKKLQEQREKEMVEKQKQ 204
              +Q    RR       Q  R +  V ++++
Sbjct: 1792 GSSQSTSRRR-------QRSRSRSRVTRRRR 1815



 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 69/209 (33%), Positives = 94/209 (44%), Gaps = 35/209 (16%)

Query: 8   LKQGRRHESKDKSSKKHKSEEHNDKEHSSDK------GRERLNSSENGEDRHKRKERKSS 61
           L Q    ES   S +  K   H      S K          ++SS   ++R      ++ 
Sbjct: 412 LPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNR---SHGRAK 468

Query: 62  RGRSHSRSRSRERRHRSRS-RERKKSRSRSRE-RKKSRSRSRERKKSRSRSRERKRRIRS 119
           R +SHS + SR R  RSRS    K+ RSRSR   K+  SRSR  +  RSRS +R  R RS
Sbjct: 469 RDKSHSHTPSR-RMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRS 527

Query: 120 RSRSRSRHRHRTRSRSRTR---SRSRDRKKR-IEKPRRFSRSLSRTPS--------PPPF 167
             R       R RSRS  R   SRSR+ ++R   +  R  RS SR+P+         P  
Sbjct: 528 PQR-------RGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPAR 580

Query: 168 RGRNTAMDAQEALARRLERAKKLQEQREK 196
           RGR+ +       ARR  R++    +R +
Sbjct: 581 RGRSRS----RTPARRRSRSRTPTRRRSR 605



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 39/141 (27%), Positives = 67/141 (47%), Gaps = 12/141 (8%)

Query: 17  KDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSH-SRSRSRERR 75
           ++ SS +  + +   K+   D+GR   +SS       +R+ +KSS+ + H S S S++R+
Sbjct: 175 RESSSSRSPTPKQKKKKKKKDRGRRSESSSP------RRERKKSSKKKKHRSESESKKRK 228

Query: 76  HRS-----RSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHR 130
           HRS     + + + K R RSR    +    R  + + + S       RSRSRS +   H 
Sbjct: 229 HRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHT 288

Query: 131 TRSRSRTRSRSRDRKKRIEKP 151
           T    R+ S +  R+   + P
Sbjct: 289 TALAGRSPSPASGRRGEGDAP 309



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 34/131 (25%), Positives = 61/131 (46%)

Query: 7   FLKQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSH 66
           F  Q R  E+K  + +  K      +  SS     +    +  +DR +R E  S R    
Sbjct: 151 FDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERK 210

Query: 67  SRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSR 126
             S+ ++ R  S S++RK      + ++KS+ + R+R +S + + + +R  RS S   + 
Sbjct: 211 KSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSAS 270

Query: 127 HRHRTRSRSRT 137
               +RSRSR+
Sbjct: 271 SSDTSRSRSRS 281



 Score = 52.4 bits (124), Expect = 7e-07
 Identities = 40/157 (25%), Positives = 72/157 (45%), Gaps = 8/157 (5%)

Query: 21  SKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRS 80
           ++ H+  E N+K++      ERL ++    D +        + R+    +      +  S
Sbjct: 119 TETHQLAELNEKKN------ERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYS 172

Query: 81  RERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSR 140
             R+ S SRS   K+ + + ++ +  RS S    RR R +S  + +HR  + S+ R    
Sbjct: 173 LVRESSSSRSPTPKQKKKKKKKDRGRRSESSS-PRRERKKSSKKKKHRSESESKKRKHRS 231

Query: 141 SRDRKKRIEKPRRFSRSLSRTPSPPPFRG-RNTAMDA 176
              + KR  K ++  RS S TP+P   R  R+T+ D+
Sbjct: 232 PTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADS 268



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 49/154 (31%), Positives = 74/154 (48%), Gaps = 8/154 (5%)

Query: 3   RTNFFLKQGRRHE-SKDKSSKKHKSEEHNDKEHSSDKGRERLNSS-ENGEDR-HKRKERK 59
           R+   +++GR H  +  +  +   S E  +K  +S + R R NSS E  + R   R+ R 
Sbjct: 703 RSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQR-RSRSNSSPEMKKSRISSRRSRS 761

Query: 60  SSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRS 119
            S  RS ++SR   RR  S S    K +S++  R +SRS S + K   ++SR   RR RS
Sbjct: 762 LSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPR-RSRSGSSQPK---AKSRTPPRRSRS 817

Query: 120 RSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRR 153
            S    + + +T SR    S S   K +   P R
Sbjct: 818 SSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPR 851



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 48/174 (27%), Positives = 68/174 (39%), Gaps = 23/174 (13%)

Query: 10  QGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRS 69
           +GRR ES     ++ KS +   K  S  + ++R + S   + + K K++K  R RS + +
Sbjct: 196 RGRRSESSSPRRERKKSSKKK-KHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPA 254

Query: 70  RSRERRHRSRSRERKKSRSRSRERKKSRSRSRERK------KSRSRSRERKRR------- 116
               R HRS S +   S   SR    SRSRS   K        RS S    RR       
Sbjct: 255 PKSRRAHRSTSADSASSSDTSR----SRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPF 310

Query: 117 ----IRSRSRSRSRHRHRTRSRSRTRSRSRDRK-KRIEKPRRFSRSLSRTPSPP 165
                 S  R  S      +  S    + +D+K K   +P       S  P PP
Sbjct: 311 SEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPP 364



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 53/209 (25%), Positives = 79/209 (37%), Gaps = 33/209 (15%)

Query: 21   SKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSH----SRSRSRERRH 76
            S+   S+E + K  +S + R   +SS + + + +   R+ SR  S     S+SR   RR 
Sbjct: 1537 SRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRS 1596

Query: 77   RSRSRERKKSRSRSRERKKSRSRSRERKK----------SRSRSRERKR----------- 115
            RS S    K + R+  R +S S S    K          SRS S  + R           
Sbjct: 1597 RSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTE 1656

Query: 116  --------RIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPF 167
                       +R  SRS    +T+SR+  R RS      + +  R SR      S P  
Sbjct: 1657 SSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPET 1716

Query: 168  RGRNTAMDAQEALARRLERAKKLQEQREK 196
            R R      +       E A+K +  R +
Sbjct: 1717 RSRTPPRHRRSPSVSSPEPAEKSRSSRRR 1745



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 40/128 (31%), Positives = 54/128 (42%), Gaps = 3/128 (2%)

Query: 40  RERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRE---RKKSRSRSRERKKS 96
           R    SS + E + +   R S  G S  R +S     +S SR    + K ++    R++S
Sbjct: 870 RSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRS 929

Query: 97  RSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSR 156
            S S     SR  SR   RR RS S   +         S + S S D K + E P R S 
Sbjct: 930 HSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSH 989

Query: 157 SLSRTPSP 164
           S S +P P
Sbjct: 990 SGSISPYP 997



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 54/210 (25%), Positives = 80/210 (38%), Gaps = 48/210 (22%)

Query: 10  QGRRHESKDKSSKKHKSEEHNDKEHSS--DKGRERLN-------SSENGEDRHKRKERKS 60
           Q R   +     KK +      +  SS   K + RL+       SS   + + +   R+S
Sbjct: 738 QRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRS 797

Query: 61  SRGRSHSRSRSRE--RRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIR 118
             G S  +++SR   RR RS S    K +S++  R+ S S S    K +S +  R+  I 
Sbjct: 798 RSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQ-SHSSSSPHPKVKSGTPPRQGSIT 856

Query: 119 S------------------------RSRSRSRHRHRTRSRSRTRSRSRDRK--------- 145
           S                        +SR+ SRH     S  R +S +  R+         
Sbjct: 857 SPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQ 916

Query: 146 ---KRIEKPRRFSRSLSRTPSPPPFRGRNT 172
              K I  PR+ S S S +PSP     R T
Sbjct: 917 PKVKAIISPRQRSHSGSSSPSPSRVTSRTT 946



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 45/170 (26%), Positives = 76/170 (44%), Gaps = 17/170 (10%)

Query: 9   KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSEN---GEDRHKRKERKSSRGRS 65
           ++GR   S ++ +K   S+  +    S +  + R++S  +      R K K R S R RS
Sbjct: 720 RRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLR-RS 778

Query: 66  HSRS------RSRERRHRSRS-RERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIR 118
            S S      +S+    RSRS   + K++SR+  R +SRS S    K +S++  R+    
Sbjct: 779 LSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPR-RSRSSSSPPPKQKSKTPSRQSHSS 837

Query: 119 SRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRS-----LSRTPS 163
           S    + +     R  S T  ++ ++    ++   F  S      SRTPS
Sbjct: 838 SSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPS 887



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 42/155 (27%), Positives = 66/155 (42%), Gaps = 13/155 (8%)

Query: 21   SKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR-------SRSRE 73
            S+   S E N+K  +    RER  S  + + +   +     R RS S        S S +
Sbjct: 1497 SRSPSSPELNNKCLTPQ--RERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQ 1554

Query: 74   RRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRS 133
             R  S S    K+++R+  R++SRS S     S+SR   R+ R  S    + + R   R+
Sbjct: 1555 ERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRA 1614

Query: 134  RSRTRSRSRDR----KKRIEKPRRFSRSLSRTPSP 164
            +S + S    +    +    + R  S S  R PSP
Sbjct: 1615 QSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSP 1649



 Score = 37.0 bits (84), Expect = 0.029
 Identities = 41/154 (26%), Positives = 67/154 (43%), Gaps = 7/154 (4%)

Query: 13   RHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSR 72
            R  S+  SS + K+     +  S       LN+      R +     S   ++ +R+   
Sbjct: 1475 RGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLG 1534

Query: 73   ERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTR 132
            +R     S+E     S S + ++S S S    K+++R+      +R RSRS S     ++
Sbjct: 1535 QRSRSGSSQELDVKPSASPQ-ERSESDSSPDSKAKTRT-----PLRQRSRSGSSPEVDSK 1588

Query: 133  SR-SRTRSRSRDRKKRIEKPRRFSRSLSRTPSPP 165
            SR S  RSRS    +  +KPR   R+ S + S P
Sbjct: 1589 SRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSP 1622



 Score = 36.6 bits (83), Expect = 0.038
 Identities = 37/163 (22%), Positives = 54/163 (33%), Gaps = 8/163 (4%)

Query: 8    LKQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHS 67
            +++GR  E      K+  S   +    SS       +SS +           SS   S  
Sbjct: 2590 VREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSP 2649

Query: 68   RSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSR---ERKRRI-----RS 119
                   +   +    KK     R  +  R      + SRS S    ER+R       R 
Sbjct: 2650 SPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRD 2709

Query: 120  RSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTP 162
            +  S S    R   R  +RS S  R++    PR      SR+P
Sbjct: 2710 QQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRSP 2752



 Score = 35.8 bits (81), Expect = 0.064
 Identities = 35/112 (31%), Positives = 48/112 (42%), Gaps = 14/112 (12%)

Query: 54  KRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRER 113
           K  +  SS     S   ++  RH S S E  K        ++  S       S++RS  R
Sbjct: 411 KLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPT----SKNRSHGR 466

Query: 114 KRRIRSRSRSRSRHRHRTRSRS---RTRSRSRDRKKRIEKPRRFSRSLSRTP 162
            +R +S S + SR   R+RS +   R RSRSR   KR         S SR+P
Sbjct: 467 AKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKR-------GHSRSRSP 511


>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
          Length = 484

 Score = 93.2 bits (230), Expect = 3e-19
 Identities = 66/173 (38%), Positives = 88/173 (50%), Gaps = 26/173 (15%)

Query: 59  KSSRGRSHSRSRSRERRHRSRSRER-KKSRSRSRERKKSRSRSRERKKS----RSRSRER 113
           K    R HSRSRSR RR R+ S  R ++SRSRSR R  S+SRSR R KS    RS SRER
Sbjct: 241 KKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRER 300

Query: 114 KRRIRSRSRSRSR--------------------HRHRTRSRSRTRSRSRDRKKRIEKPRR 153
            RR RS S++R +                     R R+ SR R R RSR   +  +KPR 
Sbjct: 301 GRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRS 360

Query: 154 FSRSLSRTPSPPPF-RGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQ 205
             R LSR+PSP    + +    D + +   R     K ++ ++KE   ++K +
Sbjct: 361 PKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSE 413



 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 47/145 (32%), Positives = 83/145 (57%), Gaps = 7/145 (4%)

Query: 12  RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRS 71
           RR  SK +S ++ KS     + HS ++GR   ++S+  + + + KE+K  R ++  +S S
Sbjct: 275 RRSHSKSRSRRRSKSPRRR-RSHSRERGRRSRSTSKTRDKKKEDKEKK--RSKTPPKSYS 331

Query: 72  RERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRS----RSRERKRRIRSRSRSRSRH 127
             RR RS SRER++ RSRS  R   + RS +RK SRS    R ++ K++ + + RSR   
Sbjct: 332 TARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDER 391

Query: 128 RHRTRSRSRTRSRSRDRKKRIEKPR 152
              T  + +++ + +DR+++ E  +
Sbjct: 392 ERSTSKKKKSKDKEKDRERKSESDK 416



 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 64/208 (30%), Positives = 105/208 (50%), Gaps = 19/208 (9%)

Query: 9   KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 68
           ++ RRH      S++ ++   +    S  + R R +S    + R +R+ +   R RSHSR
Sbjct: 243 EEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHS----KSRSRRRSKSPRRRRSHSR 298

Query: 69  SRSRERRHRSRSRERKKS---RSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRS 125
            R R  R  S++R++KK    + RS+   KS S +R   +SRS SRER+RR RSRS +RS
Sbjct: 299 ERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTAR---RSRSASRERRRR-RSRSGTRS 354

Query: 126 RHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLE 185
             + R+  R  +RS S  R K+ EK +   +  SR         +  + D ++   R+ E
Sbjct: 355 PKKPRSPKRKLSRSPSPRRHKK-EKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSE 413

Query: 186 RAKKLQ-------EQREKEMVEKQKQQE 206
             K ++       E+ +    EK+K++E
Sbjct: 414 SDKDVKQVTRDYDEEEQGYDSEKEKKEE 441



 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 56/201 (27%), Positives = 85/201 (42%), Gaps = 43/201 (21%)

Query: 42  RLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSR 101
           +LN    G      K   SS+    +  R RE +    +      +   R   +SRSRSR
Sbjct: 197 KLNHVAAGLVSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSR 256

Query: 102 ERKKSRSRSRERKRRIRSRSRSRSRHRHRTRS---------------RSRTRSRSRDRKK 146
            R+++ S SR R+ R RSR RS S+ R R RS               RSR+ S++RD+KK
Sbjct: 257 -RRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKK 315

Query: 147 R------------------------IEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALAR 182
                                     E+ RR SRS +R+P  P    R     ++    R
Sbjct: 316 EDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKL---SRSPSPR 372

Query: 183 RLERAKKLQEQREKEMVEKQK 203
           R ++ KK  + +E+   E+++
Sbjct: 373 RHKKEKKKDKDKERSRDERER 393



 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 40/123 (32%), Positives = 62/123 (50%), Gaps = 13/123 (10%)

Query: 85  KSRSRSRERKKSRSRSRERKKSRSRSRE--RKRRIRSRSRSRSRHRHRTRSRSRTRSRSR 142
           KS + S+E +++  R RE +   S + E  +K   R  SRSRSR R R    S    RSR
Sbjct: 211 KSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSR 270

Query: 143 DRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQ 202
            R +R    R  S+S SR  S  P R R+ + +       R  R++   + R+K+  +K+
Sbjct: 271 SRSRR----RSHSKSRSRRRSKSPRRRRSHSRE-------RGRRSRSTSKTRDKKKEDKE 319

Query: 203 KQQ 205
           K++
Sbjct: 320 KKR 322


>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
          Length = 2426

 Score = 92.8 bits (229), Expect = 4e-19
 Identities = 78/221 (35%), Positives = 107/221 (48%), Gaps = 50/221 (22%)

Query: 7    FLKQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSH 66
            F+K    HE     SKK+K+ +  +KE   D      +S  +   R K  E KS +  S 
Sbjct: 1793 FVKVKDTHEK----SKKNKNRDKGEKEKKRD------SSLRSRSKRSKSSEHKSRKRTSE 1842

Query: 67   SRSRSRER-----------RHRSRSRERK---KSRSRSRERK-----------KSRSRSR 101
            SRSR+R+R           R RSRSR R+   +SRS+SR R+           K RS+SR
Sbjct: 1843 SRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSR 1902

Query: 102  ERKKSRSRSRERKRRIRSRSRSRSR--------HRHRTRSRSRTRS-------RSRDRKK 146
            ERK+ RS SR+ ++ +R+RSR+ SR         R R+RS  R RS       RSR   +
Sbjct: 1903 ERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSR 1962

Query: 147  RIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERA 187
            R   P R SR+ SR    P  R R  +  ++    RR  R+
Sbjct: 1963 RSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRS 2003



 Score = 87.8 bits (216), Expect = 1e-17
 Identities = 83/279 (29%), Positives = 133/279 (47%), Gaps = 34/279 (12%)

Query: 2    IRTNFFLKQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSS 61
            +R+     +   H+S+ ++S+          +  S + + R  S         R+ R+SS
Sbjct: 1822 LRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRS-------RSRRRRRSS 1874

Query: 62   RGRSHSRSR---SRERR-----HRSRSRERKKSRSRSRERKKS-RSRSR-ERKKSRSRSR 111
            R RS SR R   S+E+R     HRS+SRERK+ RS SR+ +K+ R+RSR   ++SRS + 
Sbjct: 1875 RSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTP 1934

Query: 112  ERKRRIRSRSRSRS-----RHRHRTRS-RSRTRS-RSRDRKKRIEKPRRFSRSLSRTPSP 164
             R+RR RS  R RS       R RT S RSRT S RSR   +R   P R SR+ SR    
Sbjct: 1935 SRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRT 1994

Query: 165  PPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQEIAAAAATGGSVLNVAALL 224
            P  R R+ ++  + + +    R ++ +    +       +++ + ++  G S   +  L 
Sbjct: 1995 PSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKRLTDL- 2053

Query: 225  ASGTQVTPQIAMAAQMAALQAKAL-AETGIAVPSYYNPA 262
                      A   ++A   A A+ A+ G+ +P    PA
Sbjct: 2054 --------DKAQLLEIAKANAAAMCAKAGVPLPPNLKPA 2084



 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 58/163 (35%), Positives = 80/163 (49%), Gaps = 16/163 (9%)

Query: 16   SKDKSSKKHKSEEHNDKEH--SSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRE 73
            S  + + +  SEE +D E         E+   ++N +   K K+R SS      RS+S E
Sbjct: 1774 SMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSE 1833

Query: 74   RRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSR--------- 124
             + R R+ E  +SR+R R  K    RS+ R +SRSR R R  R RS+SR R         
Sbjct: 1834 HKSRKRTSE-SRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRK 1892

Query: 125  --SRHRHRTRSRSRTRSRSRDRKKRIEKPRR--FSRSLSRTPS 163
               +HR ++R R R RS SRD +K +    R    RS S TPS
Sbjct: 1893 RSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPS 1935



 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 57/180 (31%), Positives = 92/180 (51%), Gaps = 8/180 (4%)

Query: 33   EHSSDKGRERLNSSE---NGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSR 89
            E +S+   E  +  E     +D H++ ++  +R +   + + R+   RSRS+  K S  +
Sbjct: 1777 ERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGE-KEKKRDSSLRSRSKRSKSSEHK 1835

Query: 90   SRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHR-HRTRSRSRTRSRSRDRKKRI 148
            SR+R  S SRSR RK+S S+S+  + + RSRSRSR R R  R+RS+SR R RS  ++KR 
Sbjct: 1836 SRKRT-SESRSRARKRS-SKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGR-RSVSKEKRK 1892

Query: 149  EKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQEIA 208
              P+  S+S  R       R     + A+     R  R+     +R    V +++   I+
Sbjct: 1893 RSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSIS 1952



 Score = 66.6 bits (161), Expect = 3e-11
 Identities = 51/182 (28%), Positives = 82/182 (45%), Gaps = 24/182 (13%)

Query: 43   LNSSENGEDRHKRKERKSSRGRSHSRSRSRER-----------RHRSRSRERKKSRSRSR 91
            L +S+ G DR       SS     S S S E+            H    + + + +    
Sbjct: 1756 LLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKE 1815

Query: 92   ERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKP 151
            +++ S  RSR ++   S  + RKR   SRSR+R R       RS+TRSRSR R++     
Sbjct: 1816 KKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRR----- 1870

Query: 152  RRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQEIAAAA 211
            RR SRS S++      RGR +   ++E   R  +   K +E++ K    +  ++ + A +
Sbjct: 1871 RRSSRSRSKS------RGRRSV--SKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARS 1922

Query: 212  AT 213
             T
Sbjct: 1923 RT 1924


>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
          Length = 2303

 Score = 92.8 bits (229), Expect = 4e-19
 Identities = 78/221 (35%), Positives = 107/221 (48%), Gaps = 50/221 (22%)

Query: 7    FLKQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSH 66
            F+K    HE     SKK+K+ +  +KE   D      +S  +   R K  E KS +  S 
Sbjct: 1793 FVKVKDTHEK----SKKNKNRDKGEKEKKRD------SSLRSRSKRSKSSEHKSRKRTSE 1842

Query: 67   SRSRSRER-----------RHRSRSRERK---KSRSRSRERK-----------KSRSRSR 101
            SRSR+R+R           R RSRSR R+   +SRS+SR R+           K RS+SR
Sbjct: 1843 SRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSR 1902

Query: 102  ERKKSRSRSRERKRRIRSRSRSRSR--------HRHRTRSRSRTRS-------RSRDRKK 146
            ERK+ RS SR+ ++ +R+RSR+ SR         R R+RS  R RS       RSR   +
Sbjct: 1903 ERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSR 1962

Query: 147  RIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERA 187
            R   P R SR+ SR    P  R R  +  ++    RR  R+
Sbjct: 1963 RSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRS 2003



 Score = 87.8 bits (216), Expect = 1e-17
 Identities = 83/279 (29%), Positives = 133/279 (47%), Gaps = 34/279 (12%)

Query: 2    IRTNFFLKQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSS 61
            +R+     +   H+S+ ++S+          +  S + + R  S         R+ R+SS
Sbjct: 1822 LRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRS-------RSRRRRRSS 1874

Query: 62   RGRSHSRSR---SRERR-----HRSRSRERKKSRSRSRERKKS-RSRSR-ERKKSRSRSR 111
            R RS SR R   S+E+R     HRS+SRERK+ RS SR+ +K+ R+RSR   ++SRS + 
Sbjct: 1875 RSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTP 1934

Query: 112  ERKRRIRSRSRSRS-----RHRHRTRS-RSRTRS-RSRDRKKRIEKPRRFSRSLSRTPSP 164
             R+RR RS  R RS       R RT S RSRT S RSR   +R   P R SR+ SR    
Sbjct: 1935 SRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRT 1994

Query: 165  PPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQEIAAAAATGGSVLNVAALL 224
            P  R R+ ++  + + +    R ++ +    +       +++ + ++  G S   +  L 
Sbjct: 1995 PSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKRLTDL- 2053

Query: 225  ASGTQVTPQIAMAAQMAALQAKAL-AETGIAVPSYYNPA 262
                      A   ++A   A A+ A+ G+ +P    PA
Sbjct: 2054 --------DKAQLLEIAKANAAAMCAKAGVPLPPNLKPA 2084



 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 58/163 (35%), Positives = 80/163 (49%), Gaps = 16/163 (9%)

Query: 16   SKDKSSKKHKSEEHNDKEH--SSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRE 73
            S  + + +  SEE +D E         E+   ++N +   K K+R SS      RS+S E
Sbjct: 1774 SMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSE 1833

Query: 74   RRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSR--------- 124
             + R R+ E  +SR+R R  K    RS+ R +SRSR R R  R RS+SR R         
Sbjct: 1834 HKSRKRTSE-SRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRK 1892

Query: 125  --SRHRHRTRSRSRTRSRSRDRKKRIEKPRR--FSRSLSRTPS 163
               +HR ++R R R RS SRD +K +    R    RS S TPS
Sbjct: 1893 RSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPS 1935



 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 57/180 (31%), Positives = 92/180 (51%), Gaps = 8/180 (4%)

Query: 33   EHSSDKGRERLNSSE---NGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSR 89
            E +S+   E  +  E     +D H++ ++  +R +   + + R+   RSRS+  K S  +
Sbjct: 1777 ERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGE-KEKKRDSSLRSRSKRSKSSEHK 1835

Query: 90   SRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHR-HRTRSRSRTRSRSRDRKKRI 148
            SR+R  S SRSR RK+S S+S+  + + RSRSRSR R R  R+RS+SR R RS  ++KR 
Sbjct: 1836 SRKRT-SESRSRARKRS-SKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGR-RSVSKEKRK 1892

Query: 149  EKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQEIA 208
              P+  S+S  R       R     + A+     R  R+     +R    V +++   I+
Sbjct: 1893 RSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSIS 1952



 Score = 66.6 bits (161), Expect = 3e-11
 Identities = 51/182 (28%), Positives = 82/182 (45%), Gaps = 24/182 (13%)

Query: 43   LNSSENGEDRHKRKERKSSRGRSHSRSRSRER-----------RHRSRSRERKKSRSRSR 91
            L +S+ G DR       SS     S S S E+            H    + + + +    
Sbjct: 1756 LLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKE 1815

Query: 92   ERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKP 151
            +++ S  RSR ++   S  + RKR   SRSR+R R       RS+TRSRSR R++     
Sbjct: 1816 KKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRR----- 1870

Query: 152  RRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQEIAAAA 211
            RR SRS S++      RGR +   ++E   R  +   K +E++ K    +  ++ + A +
Sbjct: 1871 RRSSRSRSKS------RGRRSV--SKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARS 1922

Query: 212  AT 213
             T
Sbjct: 1923 RT 1924


>gi|38488727 arginine/serine-rich coiled-coil 1 [Homo sapiens]
          Length = 334

 Score = 92.4 bits (228), Expect = 6e-19
 Identities = 75/235 (31%), Positives = 110/235 (46%), Gaps = 23/235 (9%)

Query: 11  GRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRG-RSHSRS 69
           GRR    ++ S+  + ++H  +  SS     R  S + G  + + K R  SR  +  S S
Sbjct: 2   GRRSSDTEEESRSKRKKKHRRRSSSSSSSDSRTYSRKKGGRKSRSKSRSWSRDLQPRSHS 61

Query: 70  RSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRH 129
             R RRHRS S     SR R R R +SR R +  +  RSRS+ R RR RSR R RS  R 
Sbjct: 62  YDRRRRHRSSSSSSYGSR-RKRSRSRSRGRGKSYRVQRSRSKSRTRRSRSRPRLRSHSRS 120

Query: 130 RTRS---RSRTRSRSRDRKKRIEKPRRFS----------RSLSRTPSPPPFRGRNTAMDA 176
             RS   R+R+RSR R+R+K  +K +R             ++ R  S     G      A
Sbjct: 121 SERSSHRRTRSRSRDRERRKGRDKEKREKEKDKGKDKELHNIKRGESGNIKAGLEHLPPA 180

Query: 177 QEALARR---LERAKKLQE-----QREKEMVEKQKQQEIAAAAATGGSVLNVAAL 223
           ++A AR    LE A K  E     +R +E  +++K+++ A        V  + A+
Sbjct: 181 EQAKARLQLVLEAAAKADEALKAKERNEEEAKRRKEEDQATLVEQVKRVKEIEAI 235



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 48/235 (20%), Positives = 92/235 (39%), Gaps = 27/235 (11%)

Query: 12  RRHESKDKSSKKHKSEEHNDKEHSSDKG---RERLNSSENGEDRHKRKERKSSRGRSHSR 68
           RR   +  SS  + S     +  S  +G   R + + S++   R + + R  S  RS  R
Sbjct: 64  RRRRHRSSSSSSYGSRRKRSRSRSRGRGKSYRVQRSRSKSRTRRSRSRPRLRSHSRSSER 123

Query: 69  SRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHR 128
           S  R  R RSR RER+K R + +         RE++K + + +E     R  S +     
Sbjct: 124 SSHRRTRSRSRDRERRKGRDKEK---------REKEKDKGKDKELHNIKRGESGNIKAGL 174

Query: 129 HRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAK 188
                  + ++R +   +   K     ++  R         +    + Q  L  +++R K
Sbjct: 175 EHLPPAEQAKARLQLVLEAAAKADEALKAKERNEE----EAKRRKEEDQATLVEQVKRVK 230

Query: 189 KLQE-----------QREKEMVEKQKQQEIAAAAATGGSVLNVAALLASGTQVTP 232
           +++            +  KE+ +  +  E+  A +T G    VA   ++  ++ P
Sbjct: 231 EIEAIESDSFVQQTFRSSKEVKKSVEPSEVKQATSTSGPASAVADPPSTEKEIDP 285


>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
          Length = 754

 Score = 92.4 bits (228), Expect = 6e-19
 Identities = 67/233 (28%), Positives = 112/233 (48%), Gaps = 32/233 (13%)

Query: 3   RTNFFLKQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSR 62
           R N   K+ + H+S  K     ++ E +DK  +  K R +  S    +++ K KER S  
Sbjct: 418 RKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKH 477

Query: 63  GRSHS---RSRSRERRHRSRSRERKKSRSRSRERKKSRSR-------SRERKKSRSRSRE 112
            R+     RSRS+ R H +   + K+S S+ +++++SRS+       S+  +   S+S+E
Sbjct: 478 NRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKE 537

Query: 113 RKRRIRSRSRSR--SRHRHRTRSRSRTRSRSRDRKKRI--------------------EK 150
           + RR +SRSR    ++ +H   SR+R RSRSRDR +R+                    ++
Sbjct: 538 KDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQE 597

Query: 151 PRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQK 203
            RR  RS SR    PP R R+     +   +R  ER +     ++K   ++ K
Sbjct: 598 YRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESK 650



 Score = 89.0 bits (219), Expect = 6e-18
 Identities = 75/226 (33%), Positives = 109/226 (48%), Gaps = 44/226 (19%)

Query: 9   KQGRRHESKDKSSKKHKSEEHNDKEH----SSDKGRERLNSSEN---GEDRHKRKERKSS 61
           K   R +SK+KS  K +  +HN  E     S  KGR+  N  E     + + K +ER  S
Sbjct: 457 KSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRS 516

Query: 62  RGRS-----------HSRSRSRERRHRSRSRE------------RKKSRSRSRER-KKSR 97
           + +S           HS+S+ ++RR +SRSRE            R + RSRSR+R ++ R
Sbjct: 517 KEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVR 576

Query: 98  SRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRS 157
           SR+ +R +SRS+   R R    R R RSR R R       RSRS+DR++R    RR SRS
Sbjct: 577 SRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPG--RSRSKDRRRR----RRDSRS 630

Query: 158 LSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQK 203
             R  S    R ++   + +   + R E +     + EK M  K +
Sbjct: 631 SEREESQS--RNKDKYRNQESKSSHRKENS-----ESEKRMYSKSR 669



 Score = 82.4 bits (202), Expect = 6e-16
 Identities = 70/212 (33%), Positives = 106/212 (50%), Gaps = 22/212 (10%)

Query: 9   KQGRRHESKDKSSK-KHKSEEHNDKEHSSDKGRERLNSSENGE---DRHKRKERKSSRGR 64
           K   R  SK+KS + + KS EH   +HS  K ++R   S + E    + K      +R R
Sbjct: 509 KDQERSRSKEKSKQLESKSNEH---DHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRER 565

Query: 65  SHSRSRSRERRHRSRSRERKKSRS--RSRE---RKKSRSRSRERKKSRSRSRERKRRIRS 119
           S SR RSR  R R+  R+R +S+   R RE   R++ RSRSRER+    RSR + RR R 
Sbjct: 566 SRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRR-RR 624

Query: 120 RSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEA 179
           R  SRS  R  ++SR++ + R+++ K    K    S     + S    R  N++ +++E 
Sbjct: 625 RRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKS----RDHNSSNNSREK 680

Query: 180 LARR----LERAKKLQEQRE-KEMVEKQKQQE 206
            A R      + K+  +  E K  + K K+ E
Sbjct: 681 KADRDQSPFSKIKQSSQDNELKSSMLKNKEDE 712



 Score = 68.9 bits (167), Expect = 7e-12
 Identities = 86/381 (22%), Positives = 158/381 (41%), Gaps = 70/381 (18%)

Query: 10  QGRRHESKDKSSKKHKSEEHNDKEHSSDKGR---ERLNSSENGEDRHKRKERKSSRGRSH 66
           Q  R  S ++  K  KSE +  KE+     R    ++    N  +   RK  K  + + H
Sbjct: 370 QRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDH 429

Query: 67  SRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERK------RRIRSR 120
            +S S+ER  R  S +  K +++ ++R KS+SRS+ ++KS+S+ R+ K      +R+RSR
Sbjct: 430 -KSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSR 488

Query: 121 SRSR-------------SRHRHRTRSRSR-------TRSRSRDRKKRIEKPRRF---SRS 157
           S+ R             S+ + + RSRS+       ++S   D  K  EK RR    SR 
Sbjct: 489 SKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRE 548

Query: 158 LSRTPSPPPFRGRNTAMDAQEALARRL---------ERAKKLQEQREKEMVEKQKQQEIA 208
              T     +  R          +RR+          R+K+    RE+E   + + +   
Sbjct: 549 CDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRE 608

Query: 209 AAAATGGSVLNVAALLASGTQVTPQIAMAAQMAALQAKALAETGIAVPSYYNPAAVNPMK 268
                G S        +   +   + + +++    Q++           Y N  + +  +
Sbjct: 609 RRTPPGRS-------RSKDRRRRRRDSRSSEREESQSR-------NKDKYRNQESKSSHR 654

Query: 269 FAEQEKKRKMLWQGK----------KEGDKSQSAEIWEKLNFGNKDQNVKFRKLMGIKSE 318
               E +++M  + +          K+ D+ QS   + K+   ++D  +K   L     E
Sbjct: 655 KENSESEKRMYSKSRDHNSSNNSREKKADRDQSP--FSKIKQSSQDNELKSSMLK--NKE 710

Query: 319 DEAGCSSVDEESYKTLKQQEE 339
           DE   SSV++E+ K+  Q+ +
Sbjct: 711 DEKIRSSVEKENQKSKGQEND 731



 Score = 58.5 bits (140), Expect = 9e-09
 Identities = 44/184 (23%), Positives = 80/184 (43%), Gaps = 33/184 (17%)

Query: 9   KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 68
           ++ +RH+S   SS      + +    SS    +  +++E    + K+K RK+SR +    
Sbjct: 186 EEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSR-KHKKE 244

Query: 69  SRSRERRHRSRSRE-----------------------------RKKSRSRSRERKKSRSR 99
            + R++  +S S E                             RK       + +K+R R
Sbjct: 245 KKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRER 304

Query: 100 SRERKKSRSRSRE---RKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSR 156
            RER+ +   S+    ++R + +RS  + + R   R R+ +RSRSRDR +R E P  + +
Sbjct: 305 ERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQ 364

Query: 157 SLSR 160
            + R
Sbjct: 365 EMQR 368



 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 55/237 (23%), Positives = 100/237 (42%), Gaps = 53/237 (22%)

Query: 15  ESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRER 74
           E + K+ ++ +  E N         + RL  + +G    K K R   R R+ SRSRSR+R
Sbjct: 296 EKERKNRERERERECNPPNSQPASYQRRLLVTRSGR---KIKGRGPRRYRTPSRSRSRDR 352

Query: 75  RHRSRS---------------------------------RERKKSRSRSRERK------- 94
             RS +                                 +E ++S  R +ERK       
Sbjct: 353 FRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNV 412

Query: 95  -KSRSRSRERKKS----RSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIE 149
            +S +R  E++K     +S S+ER  R  S    + +++ + R++S++RS+S+++ K  E
Sbjct: 413 SESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKE 472

Query: 150 KPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQE 206
           +  + +R+  +       R R+   D +    +  +   K ++Q      EK KQ E
Sbjct: 473 RDSKHNRNEEKR-----MRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLE 524



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 40/207 (19%), Positives = 95/207 (45%), Gaps = 18/207 (8%)

Query: 12  RRHESKDKSSKKHKSEEHNDKEH-SSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRS- 69
           RR+ +  +S  + +        H   +  R +     +GE   K  + + +  + + RS 
Sbjct: 339 RRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSP 398

Query: 70  -RSRERR---HRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERK------RRIRS 119
            R +ER+   HR+ S    +   + ++ K  +S S+ER   R+  ++ K      +R +S
Sbjct: 399 VRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKS 458

Query: 120 RSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEA 179
           +SRS+S+ + +++ R    +R+ +++ R     R   ++         +G++      + 
Sbjct: 459 KSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKD------QE 512

Query: 180 LARRLERAKKLQEQREKEMVEKQKQQE 206
            +R  E++K+L+ +  +    K K+++
Sbjct: 513 RSRSKEKSKQLESKSNEHDHSKSKEKD 539



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 42/165 (25%), Positives = 76/165 (46%), Gaps = 19/165 (11%)

Query: 13  RHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKE--RKSSRGRSHSRSR 70
           R  S+ K   +++ +E+  +  S  + R         +DR +R+   R S R  S SR++
Sbjct: 582 RDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNK 641

Query: 71  SRERRHRSRSRERKKSRSRSRERKKSRSR-------SRERKKSRSRSRERKRRIRSR--- 120
            + R   S+S  RK++ S S +R  S+SR       SRE+K  R +S   K +  S+   
Sbjct: 642 DKYRNQESKSSHRKEN-SESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNE 700

Query: 121 ---SRSRSRHRHRTRS---RSRTRSRSRDRKKRIEKPRRFSRSLS 159
              S  +++   + RS   +   +S+ ++     EK ++F    S
Sbjct: 701 LKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNKKFDHESS 745



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 34/154 (22%), Positives = 68/154 (44%), Gaps = 13/154 (8%)

Query: 3   RTNFFLKQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSR 62
           R   + ++GR    + ++       +   +     +  ER  S    +D+++ +E KSS 
Sbjct: 594 REQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSH 653

Query: 63  GRSHSRS------RSRERRHRSRSRERKKSRSRSRERK-KSRSRSRERKKSRSRSRERKR 115
            + +S S      +SR+    + SRE+K  R +S   K K  S+  E K S  +++E   
Sbjct: 654 RKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKE-DE 712

Query: 116 RIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIE 149
           +IRS     S  +   +S+ +      ++ K+ +
Sbjct: 713 KIRS-----SVEKENQKSKGQENDHVHEKNKKFD 741


>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
           [Homo sapiens]
          Length = 213

 Score = 92.0 bits (227), Expect = 8e-19
 Identities = 58/192 (30%), Positives = 95/192 (49%), Gaps = 9/192 (4%)

Query: 21  SKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKR---KERKSSRGRSHSRSRSRERRHR 77
           SK      H + E + D+ RER   ++   DR K    ++R S R R   R R+RER   
Sbjct: 3   SKTEGRHTHTETE-TMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRER--- 58

Query: 78  SRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRI-RSRSRSRSRHRHRTRSRSR 136
            R RER+K   R  ER++ R R R+R++   R R+++R   R     R R + + R   R
Sbjct: 59  DRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMER 118

Query: 137 TRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQ-EALARRLERAKKLQEQRE 195
            R R R+++K + + R+  R   R       R R T  + + E   R  ER +K + +R+
Sbjct: 119 VRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERK 178

Query: 196 KEMVEKQKQQEI 207
           +E  E+++  ++
Sbjct: 179 RETKERERHTDM 190



 Score = 85.1 bits (209), Expect = 9e-17
 Identities = 56/196 (28%), Positives = 88/196 (44%), Gaps = 14/196 (7%)

Query: 9   KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 68
           ++ RR   +++   K    E    E    + RER    +   +R K+ +R+  R R   R
Sbjct: 21  RERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERER 80

Query: 69  SRSRERR-HRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKR---RIRSRSRSR 124
            R R+R   R R +ER+  R    +R++ + + RE ++ R R RE+++   R R   R  
Sbjct: 81  DRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRET 140

Query: 125 SRHRHRTRSRSRTRSRSR---DRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALA 181
            R R R   R R   R R   DR +  E+ R+  R   R       R R+T M+ +    
Sbjct: 141 DRERERQAERERETGRERKTEDRHRERERERKRERERKRETKE---RERHTDMERE---- 193

Query: 182 RRLERAKKLQEQREKE 197
           R+ E  +K   QRE E
Sbjct: 194 RQRETDRKRDRQRESE 209



 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 50/153 (32%), Positives = 73/153 (47%), Gaps = 17/153 (11%)

Query: 13  RHESKDKSSKKHKSEEHN-----DKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHS 67
           R +  D+  ++ +  E +     + E   DK RE    +E   +R K+KER+  R R   
Sbjct: 64  REKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDRE 123

Query: 68  RSRSRER-RHRSRSRERKKSRSRSRER-------KKSRSRSRERKKSRSRSRERKRRIRS 119
           R + +E  R R   RE  + R R  ER       +K+  R RER++ R R RERKR    
Sbjct: 124 REKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKR---- 179

Query: 120 RSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPR 152
            ++ R RH    R R R   R RDR++  E+ R
Sbjct: 180 ETKERERHTDMERERQRETDRKRDRQRESERER 212



 Score = 79.0 bits (193), Expect = 7e-15
 Identities = 46/133 (34%), Positives = 65/133 (48%), Gaps = 4/133 (3%)

Query: 12  RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRS 71
           R+ E++ +  K+ +++ H + +    K +ER    E   DR + K+++  R R   R   
Sbjct: 84  RQRETERERDKERETDRHTETDRERQKQKER--EMERVRDREREKQKEMGRERQTDRETD 141

Query: 72  RERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRT 131
           RER  R   RER+  R R  E  + R R RERK+ R R RE K R R     R R R   
Sbjct: 142 RERE-RQAERERETGRERKTE-DRHRERERERKRERERKRETKERERHTDMERERQRETD 199

Query: 132 RSRSRTRSRSRDR 144
           R R R R   R+R
Sbjct: 200 RKRDRQRESERER 212


>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
          Length = 330

 Score = 92.0 bits (227), Expect = 8e-19
 Identities = 68/161 (42%), Positives = 86/161 (53%), Gaps = 18/161 (11%)

Query: 15  ESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGR---SHSRSRS 71
           E +D+   K+K +E  D E  +D  +  L++SE  ED +K+K  + SR +   SHSRS S
Sbjct: 158 EDEDEDLSKYKLDEDED-EDDADLSKYNLDASEE-EDSNKKKSNRRSRSKSRSSHSRSSS 215

Query: 72  R-----ERRHRSRSRERKKSRSRSRERKKSRSRSRER-KKSRSRSRE-------RKRRIR 118
           R       R RSRSR R  S S+SR R  SR RSR R  KSRS SR        RKR   
Sbjct: 216 RSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYS 275

Query: 119 SRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLS 159
           S S S  R+R R+RSRS +    + R+ R   P R  RS S
Sbjct: 276 SSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSS 316



 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 51/138 (36%), Positives = 70/138 (50%), Gaps = 4/138 (2%)

Query: 9   KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 68
           K  RR  SK +SS    S   +    S  + R R  SS + + R +   R+ SR R  S+
Sbjct: 197 KSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRG-SK 255

Query: 69  SRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHR 128
           SRS  R HR  S  RK+S S S     S  R+R+R +SRS S   +++ R+RSRS  R  
Sbjct: 256 SRSSSRSHRGSSSPRKRSYSSS---SSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRH 312

Query: 129 HRTRSRSRTRSRSRDRKK 146
             +   S + SRS  +KK
Sbjct: 313 RSSSGSSHSGSRSSSKKK 330



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 57/200 (28%), Positives = 85/200 (42%), Gaps = 26/200 (13%)

Query: 17  KDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRH 76
           K+   K+ + EE ++ E   D  + +L+  E+ +D    K    +     S  +   RR 
Sbjct: 146 KEVEDKESEGEEEDEDE---DLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRS 202

Query: 77  RSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSR 136
           RS+SR              S SRS  R  S S SR R R   SRSRS S  + R+RS SR
Sbjct: 203 RSKSRS-------------SHSRSSSRSSSPSSSRSRSR---SRSRSSSSSQSRSRSSSR 246

Query: 137 TRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREK 196
            RSRSR  K R       S S S   S  P +   ++  +     R+  R++       K
Sbjct: 247 ERSRSRGSKSR-------SSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRK 299

Query: 197 EMVEKQKQQEIAAAAATGGS 216
           +   + +  E    +++G S
Sbjct: 300 KRRTRSRSPERRHRSSSGSS 319


>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 275

 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 52/148 (35%), Positives = 77/148 (52%), Gaps = 7/148 (4%)

Query: 12  RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSH----S 67
           R+ E   K  KK K  E   +     K RE+       ++R KRK+ K  R R       
Sbjct: 54  RKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRE 113

Query: 68  RSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSR-SRSRSR 126
           R + +ER+ R R  ++++ R R + RKK R + R+R+K R + RERKR+ R +  R + R
Sbjct: 114 RKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGK-RERKRKKRKKEEREKKR 172

Query: 127 HRHR-TRSRSRTRSRSRDRKKRIEKPRR 153
            R+R  R + R R   R+RKK  +K RR
Sbjct: 173 ERNRKERKKERERKERRERKKERKKERR 200



 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 48/150 (32%), Positives = 77/150 (51%), Gaps = 2/150 (1%)

Query: 9   KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHK-RKERKSSRGRSHS 67
           K+ ++ E   +  +K K  E   KE    + R+R    +  E + + R+ERK  + R   
Sbjct: 64  KKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKER 123

Query: 68  RSRSRERRHRSRSRERKKSRSRSRERKKSR-SRSRERKKSRSRSRERKRRIRSRSRSRSR 126
              +++RR R R + RKK R + R+R+K R  R R+RKK +   RE+KR    + R + R
Sbjct: 124 ERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKER 183

Query: 127 HRHRTRSRSRTRSRSRDRKKRIEKPRRFSR 156
            R   R R + R + R +KK  +K R+  R
Sbjct: 184 ERKERRERKKERKKERRKKKERKKDRKTDR 213



 Score = 89.4 bits (220), Expect = 5e-18
 Identities = 44/153 (28%), Positives = 80/153 (52%), Gaps = 2/153 (1%)

Query: 9   KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 68
           ++G+  E K K  +K + E    +     K +++    + G    K+K+ +  R R + +
Sbjct: 70  ERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQ 129

Query: 69  SRSRERRHRSRSRERKKSRSRSRER-KKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRH 127
            R R+R+ R R ++R+K R R +ER K+ R R + +K+ R + RER R+ R + R R   
Sbjct: 130 RRERKRKKR-RKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKER 188

Query: 128 RHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSR 160
           R R + R + R + ++RKK  +  R+    + R
Sbjct: 189 RERKKERKKERRKKKERKKDRKTDRQTDSQVFR 221



 Score = 88.6 bits (218), Expect = 8e-18
 Identities = 52/194 (26%), Positives = 98/194 (50%), Gaps = 15/194 (7%)

Query: 12  RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRS 71
           R+ E +++  +K + E+   +E    + ++R       E   KRKER+  R       R 
Sbjct: 36  RKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQR----KERRE 91

Query: 72  RERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRT 131
           +ERR R + +++++ + R R  +K +   +ER++   + RERKR+ R R + R + R R 
Sbjct: 92  KERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKR-RKKKRRKERKRE 150

Query: 132 RSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQ 191
           + R +   R R RKKR ++ R   R  +R       + R    + +E   R+ ER K+ +
Sbjct: 151 KERGK---RERKRKKRKKEEREKKRERNR-------KERKKERERKERRERKKERKKERR 200

Query: 192 EQREKEMVEKQKQQ 205
           +++E++   K  +Q
Sbjct: 201 KKKERKKDRKTDRQ 214



 Score = 86.7 bits (213), Expect = 3e-17
 Identities = 43/178 (24%), Positives = 89/178 (50%), Gaps = 3/178 (1%)

Query: 27  EEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKS 86
           E    KE    + R+R    E   +R K++++K  +     R + RER+ + R ++RK+ 
Sbjct: 33  ESERKKERREREKRKREREKERKRERGKKEKKKRKK---RERGKERERKRKEREKQRKER 89

Query: 87  RSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKK 146
           R + R ++K   + RERK+   R R++K+  + R R   + R R R + R + R ++RK+
Sbjct: 90  REKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKR 149

Query: 147 RIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQ 204
             E+ +R  +   R       +      + ++   R+  R +K + ++E+   +++K+
Sbjct: 150 EKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKK 207



 Score = 86.3 bits (212), Expect = 4e-17
 Identities = 46/158 (29%), Positives = 79/158 (50%), Gaps = 6/158 (3%)

Query: 9   KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRER-----LNSSENGEDRHKRKERKSSRG 63
           K+ R  E + +  +K +  E   KE    K RER         E  + R +R+E++  + 
Sbjct: 38  KERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKR 97

Query: 64  RSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRS 123
           +   + R R++R R   +++K+ + R RE K+ R R R++++ + R +ERKR      R 
Sbjct: 98  KKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRE 157

Query: 124 RSRHRHRTRSRSRTRSRSR-DRKKRIEKPRRFSRSLSR 160
           R R + +   R + R R+R +RKK  E+  R  R   R
Sbjct: 158 RKRKKRKKEEREKKRERNRKERKKERERKERRERKKER 195



 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 49/164 (29%), Positives = 84/164 (51%), Gaps = 4/164 (2%)

Query: 46  SENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSR-ERKKSRS--RSRE 102
           SE  ++R +R++RK  R +   R R ++ + + + RER K R R R ER+K R   R +E
Sbjct: 34  SERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKE 93

Query: 103 RKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTP 162
           R+K +   ++R+R+ R R   + +   + R R   + R R RKKR +K RR  R   +  
Sbjct: 94  RRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKER 153

Query: 163 SPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQE 206
                R R      +    R   R ++ +E+  KE  E++K+++
Sbjct: 154 GKRE-RKRKKRKKEEREKKRERNRKERKKERERKERRERKKERK 196



 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 36/123 (29%), Positives = 59/123 (47%), Gaps = 7/123 (5%)

Query: 9   KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGR------ERLNSSENGEDRHKRKERKSS- 61
           ++GRR   K K  K+ + E    +E    K R      ER    E G+   KRK+RK   
Sbjct: 108 QRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEE 167

Query: 62  RGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRS 121
           R +   R+R   ++ R R   R++ + R +ER+K + R ++RK  R    +  R +R  +
Sbjct: 168 REKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESA 227

Query: 122 RSR 124
            +R
Sbjct: 228 FNR 230



 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 33/128 (25%), Positives = 60/128 (46%)

Query: 79  RSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTR 138
           R  ERKK R    +RK+ R + R+R++ +   ++RK+R R + R R R     + + R  
Sbjct: 32  RESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERRE 91

Query: 139 SRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEM 198
              R RKK  +K  R  R           + R      +    R+  R KK +++R++E 
Sbjct: 92  KERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREK 151

Query: 199 VEKQKQQE 206
              +++++
Sbjct: 152 ERGKRERK 159



 Score = 62.0 bits (149), Expect = 8e-10
 Identities = 38/128 (29%), Positives = 63/128 (49%), Gaps = 2/128 (1%)

Query: 78  SRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRT 137
           S S   K    R  ERKK R    +RK+ R + R+R+R  + + + + R R + R R R 
Sbjct: 21  SCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKR- 79

Query: 138 RSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKE 197
           + R + RK+R EK RR  R   +       RGR      +E   R  E  ++ + +R+K 
Sbjct: 80  KEREKQRKERREKERR-KRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKR 138

Query: 198 MVEKQKQQ 205
             +K++++
Sbjct: 139 RKKKRRKE 146



 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 36/145 (24%), Positives = 72/145 (49%), Gaps = 16/145 (11%)

Query: 69  SRSRERRHRSRSRERKKSRSRSRERKKSRSRSRER-------KKSRSRSRERKRRIRSRS 121
           S+   +R   R +ER++   R RER+K   R RER       +K R R +ER+R+ + R 
Sbjct: 26  SKPCTQRESERKKERREREKRKREREKE--RKRERGKKEKKKRKKRERGKERERKRKERE 83

Query: 122 RSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALA 181
           + R   R + R + +   + R+RK+R  + R+  +           R R      +    
Sbjct: 84  KQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKE-------RERENKQRRERKRK 136

Query: 182 RRLERAKKLQEQREKEMVEKQKQQE 206
           +R ++ ++ + +REKE  +++++++
Sbjct: 137 KRRKKKRRKERKREKERGKRERKRK 161


>gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]
          Length = 320

 Score = 90.1 bits (222), Expect = 3e-18
 Identities = 75/174 (43%), Positives = 92/174 (52%), Gaps = 30/174 (17%)

Query: 15  ESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGR---SHSRSRS 71
           E +D+   K+K +E  D E  +D  +  L++SE  ED +K+K  + SR +   SHSRS S
Sbjct: 158 EDEDEDLSKYKLDEDED-EDDADLSKYNLDASEE-EDSNKKKSNRRSRSKSRSSHSRSSS 215

Query: 72  R-----ERRHRSRSRERKKSRSRSRERKKSRSRSRER-KKSRSRSRE-------RKRRIR 118
           R       R RSRSR R  S S+SR R  SR RSR R  KSRS SR        RKR   
Sbjct: 216 RSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYS 275

Query: 119 SRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNT 172
           S S S  R+R R+RSRS   S S DRKKR        R+ SR+P      G NT
Sbjct: 276 SSSSSPERNRKRSRSRS---SSSGDRKKR--------RTRSRSPESQVI-GENT 317



 Score = 72.4 bits (176), Expect = 6e-13
 Identities = 47/117 (40%), Positives = 59/117 (50%), Gaps = 6/117 (5%)

Query: 9   KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 68
           K  RR  SK +SS    S   +    S  + R R  SS + + R +   R+ SR R  S+
Sbjct: 197 KSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRG-SK 255

Query: 69  SRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRS 125
           SRS  R HR  S  RK+S S S     S S  R RK+SRSRS     R + R+RSRS
Sbjct: 256 SRSSSRSHRGSSSPRKRSYSSS-----SSSPERNRKRSRSRSSSSGDRKKRRTRSRS 307



 Score = 66.2 bits (160), Expect = 4e-11
 Identities = 60/196 (30%), Positives = 83/196 (42%), Gaps = 30/196 (15%)

Query: 17  KDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRH 76
           K+   K+ + EE ++ E   D  + +L+  E+ +D    K    +     S  +   RR 
Sbjct: 146 KEVEDKESEGEEEDEDE---DLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRS 202

Query: 77  RSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSR 136
           RS+SR              S SRS  R  S S SR R R   SRSRS S  + R+RS SR
Sbjct: 203 RSKSRS-------------SHSRSSSRSSSPSSSRSRSR---SRSRSSSSSQSRSRSSSR 246

Query: 137 TRSRSRDRKKR--------IEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAK 188
            RSRSR  K R           PR+ S S S   S  P R R  +     +   R +R  
Sbjct: 247 ERSRSRGSKSRSSSRSHRGSSSPRKRSYSSS---SSSPERNRKRSRSRSSSSGDRKKRRT 303

Query: 189 KLQEQREKEMVEKQKQ 204
           + +    + + E  KQ
Sbjct: 304 RSRSPESQVIGENTKQ 319


>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
          Length = 715

 Score = 89.7 bits (221), Expect = 4e-18
 Identities = 62/208 (29%), Positives = 102/208 (49%), Gaps = 6/208 (2%)

Query: 2   IRTNFFLKQGRRHESKDKSSKKHKSEEHND-KEHSSDKGRERLNSSENGEDRHKRKERKS 60
           +R++ + +   R  S+ +     +   H+  + HS  K + +  +   G   +  +    
Sbjct: 302 VRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSK 361

Query: 61  SRGRSHSRSRSRERRHRSRSRERKKS-RSRSRERKKSRSRSRERKKSRSRSRERKR---R 116
            R  SHSRS S+ER HR  S  RK+S RS+S    K R  SR R  +++R R R R   +
Sbjct: 362 ERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYK 421

Query: 117 IRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDA 176
            R RSRSRS ++ R  SRSR+  ++RDR +     +    S SR+P+    R R+ +  +
Sbjct: 422 ARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRS-PS 480

Query: 177 QEALARRLERAKKLQEQREKEMVEKQKQ 204
           +E    +L    K ++ R      K++Q
Sbjct: 481 KERDHSQLGSPSKERDHRRSRSPSKERQ 508



 Score = 89.7 bits (221), Expect = 4e-18
 Identities = 63/163 (38%), Positives = 97/163 (59%), Gaps = 19/163 (11%)

Query: 14  HESKDKSSKKHKSEEHNDKEHSS-DKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSR 72
           ++++D+S  +  S+E +  +  S  K R+   S    ++R  R+ R SS+ R H RSRS 
Sbjct: 468 NKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRS- 526

Query: 73  ERRHRSRSRERKKSRSRSRERKKSRSRS----RERKKSRSRSRERKRRIRSRSRSRSRHR 128
                S+ R+R++SRS ++ER +S+SRS    RE ++SRS S+ER RR R RS S+ R R
Sbjct: 527 ----PSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRR-RWRSPSKERER 581

Query: 129 HRTRS----RSRTRSRSRDRKKRIEKPRRFSR----SLSRTPS 163
            ++RS    R  +RSRS +++    +PR  S+    S SRTPS
Sbjct: 582 RQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPS 624



 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 65/205 (31%), Positives = 102/205 (49%), Gaps = 11/205 (5%)

Query: 10  QGRRH---ESKDKSSKKHKSEEHN-DKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRS 65
           Q R H   +S+++S    +   HN  +  S ++      SS    D       +   GRS
Sbjct: 331 QSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRS 390

Query: 66  HSRSRSRERRH-RSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKR---RIRSRS 121
            S S +++R H RSRS  + + RSRSR   K+R RSR R  +++R   R R   + R RS
Sbjct: 391 QSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRS 450

Query: 122 RSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRG-RNTAMDAQEAL 180
           RSRS ++ R  SRSR+ +++RDR  R   P +  R  S+  SP   R  R +   ++E  
Sbjct: 451 RSRSPNKARDHSRSRSPNKARDR-SRSRSPSK-ERDHSQLGSPSKERDHRRSRSPSKERQ 508

Query: 181 ARRLERAKKLQEQREKEMVEKQKQQ 205
            R+   + K ++ R      K++Q+
Sbjct: 509 CRQSRSSSKERDHRRSRSPSKERQR 533



 Score = 86.7 bits (213), Expect = 3e-17
 Identities = 65/204 (31%), Positives = 101/204 (49%), Gaps = 13/204 (6%)

Query: 12  RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRS 71
           R+   + +S   +K  +H+ +  S +K R+R  S    + R + + R  ++ R  SRSRS
Sbjct: 384 RKESGRSQSGSPNKQRDHS-RSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRS 442

Query: 72  RER-RHRSRSRERKKSR--SRSRERKKSRSRSRERKKSRSR--------SRERKRRIRSR 120
             + R RSRSR   K+R  SRSR   K+R RSR R  S+ R        S+ER  R RSR
Sbjct: 443 PYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHR-RSR 501

Query: 121 SRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEAL 180
           S S+ R   ++RS S+ R   R R    E+ RR SRS ++       R  +   + +++ 
Sbjct: 502 SPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSR 561

Query: 181 ARRLERAKKLQEQREKEMVEKQKQ 204
           +   ER ++      KE   +Q +
Sbjct: 562 SPSKERDRRRWRSPSKERERRQSR 585



 Score = 83.2 bits (204), Expect = 4e-16
 Identities = 62/200 (31%), Positives = 100/200 (50%), Gaps = 17/200 (8%)

Query: 13  RHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSR 72
           R  S+ +S  K +    +   + + + R R  S     D  + +    +R RS SRS S+
Sbjct: 423 RDRSRSRSPNKARDCSRSRSPYKA-RDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSK 481

Query: 73  ERRHR-----SRSRERKKSRSRSRER--KKSRSRSRER--KKSRSRSRERKRR------- 116
           ER H      S+ R+ ++SRS S+ER  ++SRS S+ER  ++SRS S+ER+RR       
Sbjct: 482 ERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNK 541

Query: 117 IRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDA 176
            R RS+SRS    R   +SR+ S+ RDR++     +   R  SR+ S      R+ + + 
Sbjct: 542 ERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNK 601

Query: 177 QEALARRLERAKKLQEQREK 196
           Q   +R    +K+    R +
Sbjct: 602 QSGYSRPRASSKEKAHSRSR 621



 Score = 82.4 bits (202), Expect = 6e-16
 Identities = 63/189 (33%), Positives = 96/189 (50%), Gaps = 11/189 (5%)

Query: 19  KSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR--SRSRERRH 76
           +S   +K+ + + +  S +K R+   S    + R + + R  S+ R HS+  S S+ER H
Sbjct: 439 RSRSPYKARDRS-RSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDH 497

Query: 77  R-----SRSRERKKSRSRSRER--KKSRSRSRERKKSRSRSRERKR-RIRSRSRSRSRHR 128
           R     S+ R+ ++SRS S+ER  ++SRS S+ER++ +SRS  ++R R +SRS S  R  
Sbjct: 498 RRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREH 557

Query: 129 HRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAK 188
            ++RS S+ R R R R    E+ RR SRS S        R  N         A   E+A 
Sbjct: 558 RQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAH 617

Query: 189 KLQEQREKE 197
                  KE
Sbjct: 618 SRSRTPSKE 626



 Score = 78.6 bits (192), Expect = 9e-15
 Identities = 62/202 (30%), Positives = 96/202 (47%), Gaps = 38/202 (18%)

Query: 16  SKDKSSKKHKS---EEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSS--RGRSHSRSR 70
           SK++  ++ +S   E    +  SS K R+   S    ++R +R+ R  +  R RS SRS 
Sbjct: 492 SKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSP 551

Query: 71  SRERRHR-------SRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRER---------- 113
           S ER HR        R R R +S S+ RER++SRS S ER  SRSRS  +          
Sbjct: 552 SEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRAS 611

Query: 114 -KRRIRSRSRSRSRHRHRTRSRSRTR---------------SRSRDRKKRIEKPRRFSRS 157
            K +  SRSR+ S+  + ++SR+ ++                RS  R   + + R  S++
Sbjct: 612 SKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKT 671

Query: 158 LSRTPSPPPFRGRNTAMDAQEA 179
            S +PS  P  G+  + D  +A
Sbjct: 672 SSHSPSTFPSGGQTLSQDDSQA 693



 Score = 69.3 bits (168), Expect = 5e-12
 Identities = 61/200 (30%), Positives = 93/200 (46%), Gaps = 25/200 (12%)

Query: 20  SSKKHKSEEH-----NDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRER 74
           SS+K KS         +K +S  +   R+ S      R + +    SR    SRS S++R
Sbjct: 238 SSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKR 297

Query: 75  RH---RSRSRERKKSRSRSRERK--------KSRSRSRERKKSRSRSRERKRRIRSRSRS 123
            H   RS S +R  SR+RSR RK         S+SRS  + KS+++SR   RR RS + S
Sbjct: 298 THSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSR-TPRRGRSHNWS 356

Query: 124 RSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTP--------SPPPFRGRNTAMD 175
           R+  + R+ S SR+ S+ RD +      +   RS S +P        S  P + R+ +  
Sbjct: 357 RNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRS 416

Query: 176 AQEALARRLERAKKLQEQRE 195
                AR   R++   + R+
Sbjct: 417 RSPYKARDRSRSRSPNKARD 436



 Score = 69.3 bits (168), Expect = 5e-12
 Identities = 60/204 (29%), Positives = 97/204 (47%), Gaps = 27/204 (13%)

Query: 13  RHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKS--------SRGR 64
           R +S  +S    +S   + K   S   R R +S +    R + + RK         S+ R
Sbjct: 277 RPQSHSQSRSPRRSRSGSQKRTHS---RVRSHSWKRNHSRARSRTRKGILSQMGRHSQSR 333

Query: 65  SHSRSRSRE-----RRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKR---- 115
           SHS+ +S+      RR RS +  R  S+ RS    +S S+ R+ + S S  +E  R    
Sbjct: 334 SHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSG 393

Query: 116 ---RIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNT 172
              + R  SRSRS ++ R RSRSR+  ++RDR  R   P + +R  SR+ S  P++ R+ 
Sbjct: 394 SPNKQRDHSRSRSPNKARDRSRSRSPYKARDR-SRSRSPNK-ARDCSRSRS--PYKARDR 449

Query: 173 AMDAQEALARRLERAKKLQEQREK 196
           +       AR   R++   + R++
Sbjct: 450 SRSRSPNKARDHSRSRSPNKARDR 473



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 44/150 (29%), Positives = 73/150 (48%), Gaps = 4/150 (2%)

Query: 46  SENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKK 105
           S+N      RK +   +    SR +S      S SR +  +++ +R R +S S+SR  ++
Sbjct: 231 SDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMS-SRVKSYNQASTRSRPQSHSQSRSPRR 289

Query: 106 SRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPP 165
           SRS S+   +R  SR RS S  R+ +R+RSRTR     +  R  + R  S+  S+  S  
Sbjct: 290 SRSGSQ---KRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRT 346

Query: 166 PFRGRNTAMDAQEALARRLERAKKLQEQRE 195
           P RGR+       +  R    ++   ++R+
Sbjct: 347 PRRGRSHNWSRNPSKERSHSHSRSSSKERD 376



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 40/158 (25%), Positives = 65/158 (41%), Gaps = 12/158 (7%)

Query: 5   NFFLKQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGR 64
           N  +       +K  S+K+  S   + +     K R     S    D    K  K+S  R
Sbjct: 54  NSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKAR---TPSRVSTDTRTSKASKASDVR 110

Query: 65  SHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSR 124
            H R     R   SR R   +  SRS +R  SR+ +      R R+   +  + SR R+ 
Sbjct: 111 CHQR-----RGTHSRGRTPGRRGSRSSKRSPSRAST----PGRIRTHGARPGMASRVRTP 161

Query: 125 SRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTP 162
           +  +  +R +S  R R+ +R++   +PR  S+   R P
Sbjct: 162 TSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPP 199



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 41/150 (27%), Positives = 59/150 (39%), Gaps = 15/150 (10%)

Query: 43  LNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRE 102
           L S+++          K +  R+   S S  +  +S S +R  S   +R   +SR RS+ 
Sbjct: 32  LKSTKSATPNRSLVPTKPATSRNSVMSPSSSKSTKSTSTKRAPS---NRPSSRSRVRSKA 88

Query: 103 RKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTP 162
           R  SR  +  R  +    S  R   R  T SR RT  R            R SRS  R+P
Sbjct: 89  RTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGR------------RGSRSSKRSP 136

Query: 163 SPPPFRGRNTAMDAQEALARRLERAKKLQE 192
           S     GR     A+  +A R+      Q+
Sbjct: 137 SRASTPGRIRTHGARPGMASRVRTPTSQQK 166


>gi|41393554 LUC7-like isoform b [Homo sapiens]
          Length = 371

 Score = 88.6 bits (218), Expect = 8e-18
 Identities = 55/114 (48%), Positives = 70/114 (61%), Gaps = 4/114 (3%)

Query: 40  RERLNSSEN--GEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSR 97
           RE+L+       E + KR + +  R     R     RR  SR+R+R++SRSR R R++SR
Sbjct: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSR 281

Query: 98  SRSRERKK-SRSRSRERKRRIRSRSRSRSR-HRHRTRSRSRTRSRSRDRKKRIE 149
           S SRER+K SRSRSR+R RR RSRSRS SR HR  +R RS     SR+R  R E
Sbjct: 282 STSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREE 335



 Score = 82.0 bits (201), Expect = 8e-16
 Identities = 49/102 (48%), Positives = 66/102 (64%), Gaps = 5/102 (4%)

Query: 58  RKSSRGRSHSRSRSRERRHRSRSRERKKSR---SRSRERKKSRSRSRERKKSRSRSRERK 114
           RK+   +   R++ R RR   R RE + SR   SR+R+R++SRSR R R++SRS SRER+
Sbjct: 229 RKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERR 288

Query: 115 RRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSR 156
           +  RSRSR R R RHR+RSRS +R   R  + R  K  +FSR
Sbjct: 289 KLSRSRSRDRHR-RHRSRSRSHSRGHRRASRDRSAK-YKFSR 328



 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 41/110 (37%), Positives = 53/110 (48%), Gaps = 4/110 (3%)

Query: 17  KDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRH 76
           K  + K+ K  +   +     +  ERL+       R +R+ R   R R  SRS SRERR 
Sbjct: 230 KTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRK 289

Query: 77  RSRSRERKKSRSRSRERKKSRSRSR-ERKKSRSRSRERKRRIRSRSRSRS 125
            SRSR R + R   R R +SRS SR  R+ SR RS + K      SR  S
Sbjct: 290 LSRSRSRDRHR---RHRSRSRSHSRGHRRASRDRSAKYKFSRERASREES 336



 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 45/141 (31%), Positives = 67/141 (47%), Gaps = 11/141 (7%)

Query: 9   KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGR---S 65
           KQ +R++ + +  ++ + EE   +  S  + R+R  S     DR +R+ R +SR R   S
Sbjct: 235 KQEKRNQDRLRRREEREREERLSRR-SGSRTRDRRRS--RSRDRRRRRSRSTSRERRKLS 291

Query: 66  HSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRS 125
            SRSR R RRHRSRSR   +       R+ SR RS + K SR R+   +     RS    
Sbjct: 292 RSRSRDRHRRHRSRSRSHSRG-----HRRASRDRSAKYKFSRERASREESWESGRSERGP 346

Query: 126 RHRHRTRSRSRTRSRSRDRKK 146
                  S  +  SR  + K+
Sbjct: 347 PDWRLESSNGKMASRRSEEKE 367



 Score = 55.8 bits (133), Expect = 6e-08
 Identities = 47/155 (30%), Positives = 73/155 (47%), Gaps = 13/155 (8%)

Query: 17  KDKSSKKHKSEEHNDKEHSSDKGRERLN-----SSENGEDRHKRKERKSSRGRSHS---R 68
           K ++ KK   EE+ +   +S   +++L      S+  G   + R+      G+ H    +
Sbjct: 161 KVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQ 220

Query: 69  SRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHR 128
            R +  + R    E+++ R++ R R++      ER   RS SR R RR     RSRSR R
Sbjct: 221 IREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRR-----RSRSRDR 275

Query: 129 HRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPS 163
            R RSRS +R R +  + R     R  RS SR+ S
Sbjct: 276 RRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHS 310


>gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 285

 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 57/211 (27%), Positives = 92/211 (43%), Gaps = 7/211 (3%)

Query: 8   LKQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHS 67
           +++  R   +++  K+ K E H +K+   +K R+R    +    R + ++RK  R     
Sbjct: 57  IRERERQRERERQRKRAK-ERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRD 115

Query: 68  RSRSRER---RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSR 124
           R    ER   R R R R+R+K R R R+R+    + RE +  + R RER+     R R R
Sbjct: 116 RETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDR 175

Query: 125 SRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRL 184
            R R + R   R R R R R+K   + R   R   +      +R R T  D  +   R  
Sbjct: 176 ERERQKQRETRRDRDRERQREK---EDRERDRDRQKEREKDRYRERETGRDRDKERDRER 232

Query: 185 ERAKKLQEQREKEMVEKQKQQEIAAAAATGG 215
           +R K    Q+  + V  + +  + A     G
Sbjct: 233 QREKDRDRQKAIDCVPGRWEVTVMAVDCVPG 263


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.122    0.325 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,246,852
Number of Sequences: 37866
Number of extensions: 607597
Number of successful extensions: 31716
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 664
Number of HSP's successfully gapped in prelim test: 646
Number of HSP's that attempted gapping in prelim test: 6805
Number of HSP's gapped (non-prelim): 8536
length of query: 375
length of database: 18,247,518
effective HSP length: 104
effective length of query: 271
effective length of database: 14,309,454
effective search space: 3877862034
effective search space used: 3877862034
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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