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Search of human proteins with 38049014
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38049014 semenogelin I isoform b preproprotein [Homo
sapiens]
(402 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38049014 semenogelin I isoform b preproprotein [Homo sapiens] 823 0.0
gi|4506883 semenogelin I isoform a preproprotein [Homo sapiens] 761 0.0
gi|4506885 semenogelin II precursor [Homo sapiens] 578 e-165
gi|60097902 filaggrin [Homo sapiens] 58 1e-08
gi|171916097 repetin [Homo sapiens] 49 1e-05
gi|62122917 filaggrin family member 2 [Homo sapiens] 48 1e-05
gi|57864582 hornerin [Homo sapiens] 47 2e-05
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 43 4e-04
gi|4504487 histidine rich calcium binding protein precursor [Hom... 43 6e-04
gi|62244004 modulator of estrogen induced transcription isoform ... 41 0.002
gi|63176611 modulator of estrogen induced transcription isoform ... 41 0.002
gi|190194423 SPARC-like 1 [Homo sapiens] 40 0.003
gi|190341024 SPARC-like 1 [Homo sapiens] 40 0.003
gi|50409738 SRp25 nuclear protein isoform 3 [Homo sapiens] 40 0.003
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 40 0.005
gi|50409756 SRp25 nuclear protein isoform 1 [Homo sapiens] 40 0.005
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 39 0.008
gi|7706635 cornulin [Homo sapiens] 39 0.011
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 38 0.014
gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens] 38 0.014
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 38 0.019
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 38 0.019
gi|50409691 SRp25 nuclear protein isoform 4 [Homo sapiens] 38 0.019
gi|50409707 SRp25 nuclear protein isoform 2 [Homo sapiens] 38 0.019
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 37 0.024
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 37 0.024
gi|126723564 pecanex-like 1 [Homo sapiens] 37 0.032
gi|21361831 partitioning-defective protein 3 homolog [Homo sapiens] 37 0.041
gi|219555661 intraflagellar transport 81-like isoform 1 [Homo sa... 37 0.041
gi|32526901 intraflagellar transport 81-like isoform 1 [Homo sap... 37 0.041
>gi|38049014 semenogelin I isoform b preproprotein [Homo sapiens]
Length = 402
Score = 823 bits (2125), Expect = 0.0
Identities = 402/402 (100%), Positives = 402/402 (100%)
Query: 1 MKPNIIFVLSLLLILEKQAAVMGQKGGSKGRLPSEFSQFPHGQKGQHYSGQKGKQQTESK 60
MKPNIIFVLSLLLILEKQAAVMGQKGGSKGRLPSEFSQFPHGQKGQHYSGQKGKQQTESK
Sbjct: 1 MKPNIIFVLSLLLILEKQAAVMGQKGGSKGRLPSEFSQFPHGQKGQHYSGQKGKQQTESK 60
Query: 61 GSFSIQYTYHVDANDHDQSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSK 120
GSFSIQYTYHVDANDHDQSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSK
Sbjct: 61 GSFSIQYTYHVDANDHDQSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSK 120
Query: 121 GHFHRVVIHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSG 180
GHFHRVVIHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSG
Sbjct: 121 GHFHRVVIHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSG 180
Query: 181 AQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCP 240
AQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCP
Sbjct: 181 AQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCP 240
Query: 241 AHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHY 300
AHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHY
Sbjct: 241 AHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHY 300
Query: 301 GENGVQKDVSQSSIYSQTEEKAQGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSH 360
GENGVQKDVSQSSIYSQTEEKAQGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSH
Sbjct: 301 GENGVQKDVSQSSIYSQTEEKAQGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSH 360
Query: 361 EQKGRHQHGSHGGLDIVIIEQEDDSDRHLAQHLNNDRNPLFT 402
EQKGRHQHGSHGGLDIVIIEQEDDSDRHLAQHLNNDRNPLFT
Sbjct: 361 EQKGRHQHGSHGGLDIVIIEQEDDSDRHLAQHLNNDRNPLFT 402
>gi|4506883 semenogelin I isoform a preproprotein [Homo sapiens]
Length = 462
Score = 761 bits (1964), Expect = 0.0
Identities = 390/462 (84%), Positives = 392/462 (84%), Gaps = 60/462 (12%)
Query: 1 MKPNIIFVLSLLLILEKQAAVMGQKGGSKGRLPSEFSQFPHGQKGQHYSGQKGKQQTESK 60
MKPNIIFVLSLLLILEKQAAVMGQKGGSKGRLPSEFSQFPHGQKGQHYSGQKGKQQTESK
Sbjct: 1 MKPNIIFVLSLLLILEKQAAVMGQKGGSKGRLPSEFSQFPHGQKGQHYSGQKGKQQTESK 60
Query: 61 GSFSIQYTYHVDANDHDQSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSK 120
GSFSIQYTYHVDANDHDQSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSK
Sbjct: 61 GSFSIQYTYHVDANDHDQSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSK 120
Query: 121 GHFHRVVIHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSG 180
GHFHRVVIHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSG
Sbjct: 121 GHFHRVVIHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSG 180
Query: 181 AQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCP 240
AQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCP
Sbjct: 181 AQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCP 240
Query: 241 AHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHY 300
AHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHY
Sbjct: 241 AHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHY 300
Query: 301 GENGVQKDVSQSSIYSQTEEKAQGKSQIQAPNPKQEPWHGENAK---------------- 344
GENGVQKDVSQSSIYSQTEEKAQGKSQ Q P QE H + A
Sbjct: 301 GENGVQKDVSQSSIYSQTEEKAQGKSQKQITIPSQEQEHSQKANKISYQSSSTEERRLHY 360
Query: 345 GESG--------------------------------------------QSTNREQDLLSH 360
GE+G QSTNREQDLLSH
Sbjct: 361 GENGVQKDVSQRSIYSQTEKLVAGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSH 420
Query: 361 EQKGRHQHGSHGGLDIVIIEQEDDSDRHLAQHLNNDRNPLFT 402
EQKGRHQHGSHGGLDIVIIEQEDDSDRHLAQHLNNDRNPLFT
Sbjct: 421 EQKGRHQHGSHGGLDIVIIEQEDDSDRHLAQHLNNDRNPLFT 462
>gi|4506885 semenogelin II precursor [Homo sapiens]
Length = 582
Score = 578 bits (1490), Expect = e-165
Identities = 291/381 (76%), Positives = 322/381 (84%)
Query: 1 MKPNIIFVLSLLLILEKQAAVMGQKGGSKGRLPSEFSQFPHGQKGQHYSGQKGKQQTESK 60
MK I+FVLSLLLILEKQAAVMGQKGGSKG+LPS SQFPHGQKGQHY GQK +Q T+SK
Sbjct: 1 MKSIILFVLSLLLILEKQAAVMGQKGGSKGQLPSGSSQFPHGQKGQHYFGQKDQQHTKSK 60
Query: 61 GSFSIQYTYHVDANDHDQSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSK 120
GSFSIQ+TYHVD NDHD +RKSQQYDLNALHK TKS++HLGGSQQLL+ KQEGRDHDKSK
Sbjct: 61 GSFSIQHTYHVDINDHDWTRKSQQYDLNALHKATKSKQHLGGSQQLLNYKQEGRDHDKSK 120
Query: 121 GHFHRVVIHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSG 180
GHFH +VIHHKGG+AH GTQNPSQDQGNSPSGKG+SSQ SNTE+RLWVHGLSKEQ S SG
Sbjct: 121 GHFHMIVIHHKGGQAHHGTQNPSQDQGNSPSGKGLSSQCSNTEKRLWVHGLSKEQASASG 180
Query: 181 AQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCP 240
AQKGR QGGSQSSYVLQTEELV NKQQRETKNSHQNKGHYQNVV+VREEHSSK+QTSL P
Sbjct: 181 AQKGRTQGGSQSSYVLQTEELVVNKQQRETKNSHQNKGHYQNVVDVREEHSSKLQTSLHP 240
Query: 241 AHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHY 300
AHQD+LQHG KDIF+TQDELLVYNKNQHQTKNL+QDQ+HGRKA+KISY SS TEER+LH+
Sbjct: 241 AHQDRLQHGPKDIFTTQDELLVYNKNQHQTKNLSQDQEHGRKAHKISYPSSRTEERQLHH 300
Query: 301 GENGVQKDVSQSSIYSQTEEKAQGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSH 360
GE VQKDVS+ SI QTEEK GKSQ Q Q+ HG S QS++ E+ L+
Sbjct: 301 GEKSVQKDVSKGSISIQTEEKIHGKSQNQVTIHSQDQEHGHKENKISYQSSSTEERHLNC 360
Query: 361 EQKGRHQHGSHGGLDIVIIEQ 381
+KG + S G + I EQ
Sbjct: 361 GEKGIQKGVSKGSISIQTEEQ 381
Score = 210 bits (535), Expect = 2e-54
Identities = 127/301 (42%), Positives = 172/301 (57%), Gaps = 15/301 (4%)
Query: 104 QQLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYSNTE 163
++ LH+ ++ D SKG GK+ SQDQ + IS Q S+TE
Sbjct: 295 ERQLHHGEKSVQKDVSKGSISIQTEEKIHGKSQNQVTIHSQDQEHGHKENKISYQSSSTE 354
Query: 164 ERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQTEELVANKQQRETK--NSHQNKGHYQ 221
ER ++ +KG ++G S+ S +QTEE + K Q + + + Q GH +
Sbjct: 355 ER-----------HLNCGEKGIQKGVSKGSISIQTEEQIHGKSQNQVRIPSQAQEYGHKE 403
Query: 222 NVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGR 281
N ++ + SS + L +D + SK S Q E ++ K+Q+Q +QDQ+HG
Sbjct: 404 N--KISYQSSSTEERRLNSGEKDVQKGVSKGSISIQTEEKIHGKSQNQVTIPSQDQEHGH 461
Query: 282 KANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTEEKAQGKSQIQAPNPKQEPWHGE 341
K NK+SYQSSSTEERRL+YG QKDVSQSSI Q E+ +GKSQIQ PNP Q+ W G+
Sbjct: 462 KENKMSYQSSSTEERRLNYGGKSTQKDVSQSSISFQIEKLVEGKSQIQTPNPNQDQWSGQ 521
Query: 342 NAKGESGQSTNREQDLLSHEQKGRHQHGSHGGLDIVIIEQEDDSDRHLAQHLNNDRNPLF 401
NAKG+SGQS + +QDLLSHEQKGR++ S +IVI E E D HL Q N DRNP+
Sbjct: 522 NAKGKSGQSADSKQDLLSHEQKGRYKQESSESHNIVITEHEVAQDDHLTQQYNEDRNPIS 581
Query: 402 T 402
T
Sbjct: 582 T 582
Score = 138 bits (348), Expect = 8e-33
Identities = 118/382 (30%), Positives = 173/382 (45%), Gaps = 26/382 (6%)
Query: 25 KGGSKGRLPSEFSQFPHGQKGQHYSG---QKGKQQTESKGSFSIQYTYHVDANDHDQSRK 81
KG S +E + HG + S QKG+ Q S+ S+ +Q V +++
Sbjct: 153 KGLSSQCSNTEKRLWVHGLSKEQASASGAQKGRTQGGSQSSYVLQTEELVVNKQQRETKN 212
Query: 82 SQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSKGHF---HRVVIHHKGGKAHRG 138
S Q + + + H Q LH + R K F +++++K
Sbjct: 213 SHQNKGHYQNVVDVREEHSSKLQTSLHPAHQDRLQHGPKDIFTTQDELLVYNKN---QHQ 269
Query: 139 TQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQT 198
T+N SQDQ + IS S TEER HG Q VS + S +QT
Sbjct: 270 TKNLSQDQEHGRKAHKISYPSSRTEERQLHHGEKSVQKDVS-----------KGSISIQT 318
Query: 199 EELVANKQQRETK--NSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHG-SKDIFS 255
EE + K Q + + Q GH +N + + SS + + +Q G SK S
Sbjct: 319 EEKIHGKSQNQVTIHSQDQEHGHKENKISYQ---SSSTEERHLNCGEKGIQKGVSKGSIS 375
Query: 256 TQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIY 315
Q E ++ K+Q+Q + +Q Q++G K NKISYQSSSTEERRL+ GE VQK VS+ SI
Sbjct: 376 IQTEEQIHGKSQNQVRIPSQAQEYGHKENKISYQSSSTEERRLNSGEKDVQKGVSKGSIS 435
Query: 316 SQTEEKAQGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQKGRHQHGSHGGLD 375
QTEEK GKSQ Q P Q+ HG S QS++ E+ L++ K + S +
Sbjct: 436 IQTEEKIHGKSQNQVTIPSQDQEHGHKENKMSYQSSSTEERRLNYGGKSTQKDVSQSSIS 495
Query: 376 IVIIEQEDDSDRHLAQHLNNDR 397
I + + + + N D+
Sbjct: 496 FQIEKLVEGKSQIQTPNPNQDQ 517
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 58.2 bits (139), Expect = 1e-08
Identities = 105/449 (23%), Positives = 163/449 (36%), Gaps = 82/449 (18%)
Query: 17 KQAAVMGQKG--GSKGRLPSEF----------SQFPHGQKGQHYS-------GQKGKQQT 57
+ ++V+G G GS G S+ S HGQ G H GQ G++
Sbjct: 1701 QDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSG 1760
Query: 58 ESKGSFSIQYTYHVDAND----------------HDQSRKSQQYDLNALHKTTKSQRHLG 101
S GSF Q + H + H+Q+R S ++ + + T + H G
Sbjct: 1761 RS-GSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDT-IRGHPG 1818
Query: 102 ---GSQQLLHNKQEGRDHDKSKGHFHRVVIHHKG--GKAHRGTQNPS-QDQGNSPSGKGI 155
G +Q H +Q S H + + G+++ S Q + SG G
Sbjct: 1819 SSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGS 1878
Query: 156 SSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQ 215
S E S+ G G + +Q S V Q + + + E +
Sbjct: 1879 RHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSA 1938
Query: 216 NKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFS-------TQDELLVYNKNQH 268
++ H + E + S + H+D+ HG S T+ + H
Sbjct: 1939 SRNHLGSAWEQSRDGSRHPGSH----HEDRAGHGHSADSSRQSGTRHTESSSRGQAASSH 1994
Query: 269 QTKNLNQDQQHG-----------RKANKISYQSSSTEERRLHYGENGVQKDVSQS-SIYS 316
+ + ++HG R + Q+SS H G +G Q S+ S S
Sbjct: 1995 EQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDS 2054
Query: 317 QTEE-KAQGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLL----SHEQKGRHQHG-- 369
T+ AQGK+ P Q+ H E+A+G+SG+S+ R L +HEQ HG
Sbjct: 2055 DTQSVSAQGKA-----GPHQQS-HKESARGQSGESSGRSGSFLYQVSTHEQ-SESTHGQS 2107
Query: 370 --SHGGLDIVIIEQEDDSDRHLAQHLNND 396
S GG +Q DS RH A D
Sbjct: 2108 APSTGGRQGSHYDQAQDSSRHSASQEGQD 2136
Score = 56.6 bits (135), Expect = 4e-08
Identities = 88/416 (21%), Positives = 141/416 (33%), Gaps = 77/416 (18%)
Query: 41 HGQKGQHYS-------GQKGKQQTESKGSFSIQYTYHVDA-NDHDQSRKSQQYDLNALHK 92
HGQ G H G+ G+ S GSF Q + H + + H + S + + H+
Sbjct: 3034 HGQAGSHQQSHQESARGRSGETSGHS-GSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHE 3092
Query: 93 TTKSQRHLGGSQ--QLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAHRGTQNPSQDQGNSP 150
+ SQ Q G +G+ H + G + SQ + ++
Sbjct: 3093 QAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDAS 3152
Query: 151 SGKGISSQYSNTEERLWVHG------------------LSKEQTSVSGAQKGRKQGGSQS 192
G+ S S T G +S+ +V G +G ++ Q
Sbjct: 3153 RGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQG 3212
Query: 193 SYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKD 252
S V Q + + + E + ++ H +V E + H S+ S H+D+ HG
Sbjct: 3213 SSVSQDSDSEGHSEDSERWSGSASRNHRGSVQE-QSRHGSRHPRS---HHEDRAGHGHSA 3268
Query: 253 IFSTQDELLVYNKNQ-------HQTKNLNQDQQHGRKANKISY----------QSSSTEE 295
S Q + H+ + ++HG + + + Q+SS
Sbjct: 3269 DRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVR 3328
Query: 296 RRLHYGENGVQKDVSQSSIYSQTEEKAQGKSQIQAPNPKQEPWHGENAKGESGQSTNREQ 355
H+G +G Q S+ + G Q P Q+ H E+A+ SG + R
Sbjct: 3329 DSRHWGSSGSQASDSEGHSEESDTQSVSGHGQ---AGPHQQS-HQESARDRSGGRSGRSG 3384
Query: 356 DLL----SHEQK-----------GRHQHGSHGGLDIVIIEQEDDSDRHLAQHLNND 396
L +HEQ GR Q H EQ DS RH A D
Sbjct: 3385 SFLYQVSTHEQSESAHGRTRTSTGRRQGSHH--------EQARDSSRHSASQEGQD 3432
Score = 55.5 bits (132), Expect = 9e-08
Identities = 91/391 (23%), Positives = 144/391 (36%), Gaps = 59/391 (15%)
Query: 23 GQKGGSKGRLPSEFSQFPHGQKGQH-YSGQKGKQQTESKGSFSIQYTYHVDANDHDQSRK 81
G++ GS + S+ Q+GQ G ++ +GS Q VD + H S
Sbjct: 1139 GRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQ---SVDRSGHSGSHH 1195
Query: 82 SQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSKGHFHRVVI------HHKGGKA 135
S + S+Q +KQ G S H H + G+
Sbjct: 1196 SHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQE 1255
Query: 136 HRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYV 195
S+ QG+S S S ++S+ ERL SG+ G S+
Sbjct: 1256 QSSGSRTSRHQGSSVSQDSDSERHSDDSERL------------SGSASRNHHGSSRE--- 1300
Query: 196 LQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPA--HQDKLQHGSKDI 253
++++ ++ G +Q E R H +S H + HG
Sbjct: 1301 -------------QSRDGSRHPGFHQ---EDRASHGHSADSSRQSGTHHTESSSHGQA-- 1342
Query: 254 FSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSS 313
S+ ++ +H +++ Q R + Q+SS H G +G Q V+ S
Sbjct: 1343 VSSHEQARSSPGERHGSRH-QQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQ--VTNSE 1399
Query: 314 IYSQTEEKAQGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLL----SHEQKGRHQHG 369
+S+ + + QA P Q+ H E+A+G+SG+S+ R + L SHEQ HG
Sbjct: 1400 GHSEDSDTQSVSAHGQA-GPHQQS-HKESARGQSGESSGRSRSFLYQVSSHEQ-SESTHG 1456
Query: 370 ----SHGGLDIVIIEQEDDSDRHLAQHLNND 396
S GG EQ +S RH A D
Sbjct: 1457 QTAPSTGGRQGSRHEQARNSSRHSASQDGQD 1487
Score = 53.1 bits (126), Expect = 4e-07
Identities = 85/411 (20%), Positives = 141/411 (34%), Gaps = 55/411 (13%)
Query: 18 QAAVMGQKGGSKGRLPS--------EFSQFPHGQKGQHYSGQKGKQQTESKGSFSI---- 65
Q + G+ G GR S E S+ HG+ G G++G +++ S
Sbjct: 2397 QESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQ 2456
Query: 66 --QYTYHVDANDHDQSRKSQQYDL--------NALHKTTKSQRHLGGSQQLLHNKQEGRD 115
Q T H R+ Y+ + H T SQ S ++ R
Sbjct: 2457 EGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQ 2516
Query: 116 --HDKSKGHFHRVVIHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSK 173
+D+ G R H G + H + + G+S G+G S R W S+
Sbjct: 2517 TRNDEQSGDGSR----HSGSRHHEASSR-ADSSGHSQVGQGQSE--GPRTSRNWGSSFSQ 2569
Query: 174 EQTSVSGAQKGRKQGGSQS-SYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSS 232
+ S ++ + GS S ++ +E + + + + GH + R+ +
Sbjct: 2570 DSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTR 2629
Query: 233 KVQTSLCPAHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSS 292
QTS S ++ E + + + Q R + Q+SS
Sbjct: 2630 HTQTS------------SGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASS 2677
Query: 293 TEERRLHYGENGVQKDVSQSSIYSQTEEKAQGKSQIQAPNPKQEPWHGENAKGESGQSTN 352
H G +G Q S + +S+ + + QA + +Q H E+A+G SG+++
Sbjct: 2678 AVRDSGHRGYSGSQ--ASDNEGHSEDSDTQSVSAHGQAGSHQQS--HQESARGRSGETSG 2733
Query: 353 REQDLLSHEQKGRHQHGSHG-------GLDIVIIEQEDDSDRHLAQHLNND 396
L SHG G EQ DS RH A D
Sbjct: 2734 HSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQD 2784
Score = 51.2 bits (121), Expect = 2e-06
Identities = 85/385 (22%), Positives = 134/385 (34%), Gaps = 47/385 (12%)
Query: 23 GQKGGSKGRLPSEFSQFPHGQKGQH-YSGQKGKQQTESKGSFSIQYTYHVDANDHDQSRK 81
G++ GS + S+ Q+GQ G G + +GS Y VD + H S
Sbjct: 3408 GRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGS---HYEQSVDRSGHSGSHH 3464
Query: 82 SQQYDLNALHKTT--KSQRHLGGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAHRGT 139
S H T+ +S G S ++Q D G H HH+ +
Sbjct: 3465 S--------HTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQADSS 3516
Query: 140 QNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQTE 199
++ QG S + +Q S+ + G S++ SG+ +G +Q
Sbjct: 3517 RHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQ-------- 3568
Query: 200 ELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQDE 259
E + + T + GH + R+ + + S S ++ E
Sbjct: 3569 EQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENS------------SGGQAASSHE 3616
Query: 260 LLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTE 319
+ + + Q R + Q+SS H G +G Q S S +S+
Sbjct: 3617 QARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQ--ASDSEGHSEDS 3674
Query: 320 EKAQGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLL----SHEQKGRHQHG----SH 371
+ + QA P Q+ H E+ +G S + R L +HEQ HG S
Sbjct: 3675 DTQSVSAHGQA-GPHQQS-HQESTRGRSAGRSGRSGSFLYQVSTHEQ-SESAHGRAGPST 3731
Query: 372 GGLDIVIIEQEDDSDRHLAQHLNND 396
GG EQ DS RH A D
Sbjct: 3732 GGRQGSRHEQARDSSRHSASQEGQD 3756
Score = 47.4 bits (111), Expect = 2e-05
Identities = 78/383 (20%), Positives = 136/383 (35%), Gaps = 42/383 (10%)
Query: 23 GQKGGSKGRLPSEFSQFPHGQKGQH-YSGQKGKQQTESKGSFSIQYTYHVDANDHDQSRK 81
G + GS + S+ Q+GQ G G + +GS Q + S
Sbjct: 490 GGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHT 549
Query: 82 SQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAHRGTQN 141
+ Q +A H + S+ S+Q + +Q G G H HH+ +++
Sbjct: 550 TSQGRSDASHGQSGSR---SASRQTRNEEQSG------DGTRHSGSRHHEASSQADSSRH 600
Query: 142 PSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQTEEL 201
QG S + +Q S+ + G S++ SG+ G +Q
Sbjct: 601 SQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQ-------- 652
Query: 202 VANKQQRETKNSHQNK-GHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQDEL 260
+ R ++ H+++ GH + R+ + Q S S S+ ++
Sbjct: 653 -SRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNS-----------SSGQAASSHEQA 700
Query: 261 LVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTEE 320
+H +++ Q R + Q+SS H G +G Q + S +S+ +
Sbjct: 701 RSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQ--ATDSEGHSEDSD 758
Query: 321 KAQGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQKGRHQHGSHG--GLDIVI 378
QA + +Q H E+A+ SG+ + R L + SHG G +
Sbjct: 759 TQSVSGHGQAGHHQQS--HQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGV 816
Query: 379 -----IEQEDDSDRHLAQHLNND 396
EQ D+ RH A D
Sbjct: 817 RQGSHHEQARDNSRHSASQDGQD 839
Score = 47.4 bits (111), Expect = 2e-05
Identities = 81/391 (20%), Positives = 136/391 (34%), Gaps = 59/391 (15%)
Query: 23 GQKGGSKGRLPSEFSQFPHGQKGQH-YSGQKGKQQTESKGSFSIQYTYHVDANDHDQSRK 81
G + GS + S+ Q GQ G G + +GS Q VD + H S
Sbjct: 815 GVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQ---SVDRSGHSGSHH 871
Query: 82 SQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAHRGTQN 141
S ++ Q + + N+++ RD G H HH+ +++
Sbjct: 872 SHTTS-QGRSDASRGQSGSRSASRTTRNEEQSRD-----GSRHSGSRHHEASSHADISRH 925
Query: 142 PSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQTEEL 201
QG S + Q S+ + G S++ SG+ +G +Q
Sbjct: 926 SQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQ-------- 977
Query: 202 VANKQQRETKNSHQNK-GHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQDEL 260
+ R ++ H+++ GH + R+ + +TS S+ ++
Sbjct: 978 -SRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETS-----------SGGQAASSHEQA 1025
Query: 261 LVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTEE 320
+H +++ Q R + Q+SS H+G +G Q S+ +
Sbjct: 1026 RSSPGERHGSRH-QQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQ 1084
Query: 321 KAQGKSQIQAPNPKQEPWHGENAK----GESGQSTNREQDLLSHEQK-----------GR 365
G Q P Q+ H E+A+ G SG+S + + +HEQ GR
Sbjct: 1085 SVSGHGQ---DGPHQQS-HQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGR 1140
Query: 366 HQHGSHGGLDIVIIEQEDDSDRHLAQHLNND 396
Q H EQ DS RH A D
Sbjct: 1141 RQGSHH--------EQARDSSRHSASQEGQD 1163
Score = 47.4 bits (111), Expect = 2e-05
Identities = 84/389 (21%), Positives = 151/389 (38%), Gaps = 46/389 (11%)
Query: 18 QAAVMGQKGGSKGRLPS---EFSQFPHGQKGQHYSGQKGKQQTESKGSFSIQYTYHVDAN 74
Q + G G S+G E S G G H+S + ++++ S +
Sbjct: 3107 QDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTR 3166
Query: 75 DHDQSRKSQQYDLNALHKTT-------KSQRHLGGSQQLLHNKQEGRD-HDKSKGHFHRV 126
+ +QS S ++ ++ H+ + SQ G S+ ++++G S H
Sbjct: 3167 NEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSE 3226
Query: 127 VIHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRK 186
G A R + Q+Q S G S+ E+R HG S +++ SG +
Sbjct: 3227 DSERWSGSASRNHRGSVQEQ----SRHGSRHPRSHHEDRAG-HGHSADRSRQSGTRHAET 3281
Query: 187 QGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKL 246
G Q++ +++Q R + H Q+ R HS + A +D
Sbjct: 3282 SSGGQAA--------SSHEQARSSPGERHGSRHQQSADSSR--HSGIPRGQASSAVRDSR 3331
Query: 247 QHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQ 306
GS ++ E + + T++++ Q G ++ S+Q S+ + G +G
Sbjct: 3332 HWGSSGSQASDSE---GHSEESDTQSVSGHGQAG--PHQQSHQESARDRSGGRSGRSG-- 3384
Query: 307 KDVSQSSIYSQTEEKAQGKSQIQAPNPKQEPWHGENAKGESGQSTNRE-QDLL-SHEQKG 364
+ Q S + Q+ E A G++ + +++ H E A+ S S ++E QD + H
Sbjct: 3385 SFLYQVSTHEQS-ESAHGRT--RTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSS 3441
Query: 365 RH-QHGSHGGLDIVIIEQEDDSDRHLAQH 392
R + GSH EQ D H H
Sbjct: 3442 RRGRQGSH-------YEQSVDRSGHSGSH 3463
Score = 43.5 bits (101), Expect = 3e-04
Identities = 81/414 (19%), Positives = 145/414 (35%), Gaps = 100/414 (24%)
Query: 41 HGQKGQHYSGQKGKQQTESKGSFSIQYTYHVDANDHDQSRKSQQYDLNALHKTTKSQRHL 100
H Q GQ S +G + + + GS ++ D++ S S+++ +A S+ H
Sbjct: 2546 HSQVGQGQS--EGPRTSRNWGS-----SFSQDSDSQGHSEDSERWSGSA------SRNHH 2592
Query: 101 GGSQ-QLLHNKQEGRDHDKSK-GHFHRVVIHHKGGKAHRGTQNPSQ-----DQGNSPSGK 153
G +Q QL + R H + + GH H + G H T + Q +Q S +G+
Sbjct: 2593 GSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGE 2652
Query: 154 GISSQYSNTEERLWVHGLSKEQTS----------VSGAQKGRKQGGSQSSYVLQTEELVA 203
S + + + G+ Q S SG+Q +G S+ S T+ + A
Sbjct: 2653 RHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDS---DTQSVSA 2709
Query: 204 NKQQRETKNSHQ------------NKGHYQNVVEVREEHSSKV----------QTSLCPA 241
+ Q + SHQ + G + V E+ S Q S
Sbjct: 2710 HGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQ 2769
Query: 242 HQDKLQHGSKDIFSTQDELLVY------------------------NKNQHQTKNLNQDQ 277
QD +H + QD + + + + H T D
Sbjct: 2770 AQDSSRHSASQ--DGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDA 2827
Query: 278 QHGRKANKISYQSSSTEERR----LHYG----ENGVQKDVSQSSIYSQTEEKAQGKSQIQ 329
G+ ++ + +++ EE+ H G E D+S+ S Q + + +S+ Q
Sbjct: 2828 SRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQ 2887
Query: 330 APNPKQ-----------EPWHGENAKGESGQSTNREQDLLSHEQKGRHQHGSHG 372
+ Q E W G ++ G + + +D H + + HG
Sbjct: 2888 GSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHG 2941
Score = 40.4 bits (93), Expect = 0.003
Identities = 81/407 (19%), Positives = 140/407 (34%), Gaps = 65/407 (15%)
Query: 27 GSKGRLPSEFSQFPHGQKGQHYSGQKGKQQTESKGSFSIQYTYHVDANDHDQSRKSQQYD 86
G+KGR S+ P G+ + K+ E KG N H+ S+K +
Sbjct: 136 GNKGR-----SKSPRETGGKRHESSSEKK--ERKGYSPTHREEEYGKNHHNSSKKEKNKT 188
Query: 87 LNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAHRGTQNPSQDQ 146
N + +++ L + + +EG ++ G + I H T QD+
Sbjct: 189 ENT--RLGDNRKRLSERLEEKEDNEEGVYDYENTGRMTQKWIQ----SGHIATYYTIQDE 242
Query: 147 GNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQ------------SSY 194
+ + E +++ S + S S + R + SQ S
Sbjct: 243 AYDTTDSLLE------ENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSR 296
Query: 195 VLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIF 254
V Q + + + E + ++ H+ + E + S ++ +D+ HG
Sbjct: 297 VSQDRDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSRHPRSH----DEDRASHGHSADS 352
Query: 255 STQD-------ELLVYNKNQHQTKNLNQDQQHG----------RKANKISYQSSSTEERR 297
S Q + H+ + ++HG R + Q+SS R
Sbjct: 353 SRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDR 412
Query: 298 LHYGENGVQKDVSQSSIYSQTEEKAQGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDL 357
H G +G Q S+ + + G + ++ H E+ +G SG+ + R
Sbjct: 413 GHRGSSGSQASDSEGHSENSDTQSVSGHGKAGL----RQQSHQESTRGRSGERSGRSGSS 468
Query: 358 L----SHEQKGRHQHG----SHGGLDIVIIEQEDDSDRHLAQHLNND 396
L +HEQ HG S GG EQ DS RH A D
Sbjct: 469 LYQVSTHEQPD-SAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQD 514
Score = 40.4 bits (93), Expect = 0.003
Identities = 86/396 (21%), Positives = 147/396 (37%), Gaps = 67/396 (16%)
Query: 41 HGQKGQHYSGQKGKQQTESKGSFSIQYTYHVDANDHDQSRKSQQYDLNALHK--TTKSQR 98
HG S Q G + TES A+ H+Q+R S + H+ + S R
Sbjct: 1967 HGHSADS-SRQSGTRHTESSSRGQA-------ASSHEQARSSAGERHGSHHQLQSADSSR 2018
Query: 99 HLG-GSQQLL-------HNKQEGRDHDKSKGHFHRVVIHHKGGKAHRGTQNPSQDQGNSP 150
H G G Q H G S+GH + +G P Q Q +
Sbjct: 2019 HSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSED---SDTQSVSAQGKAGPHQ-QSHKE 2074
Query: 151 SGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQTEEL---VANKQQ 207
S +G S + S + EQ+ + Q GG Q S+ Q ++ A+++
Sbjct: 2075 SARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEG 2134
Query: 208 RETKNSHQ------NKGHYQNVVEVREEHSSKVQ---TSLCPAHQDKLQHGSKDIF-STQ 257
++T H +G +Q R HS TS + + Q GS+ T
Sbjct: 2135 QDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTY 2194
Query: 258 DELLVYNKNQHQTKN---------------LNQDQQHGRKANKISYQSSSTEERRLHYGE 302
D+ + ++H + + Q Q G + ++ S S + + E
Sbjct: 2195 DKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSE 2254
Query: 303 NGVQKDVSQS-SIYSQTEEKAQGKSQIQAPNPKQEPWHGENAKG--ESG----QSTNREQ 355
+ ++ S S + + +E+++ S+ + + HG +A+ +SG ++++ Q
Sbjct: 2255 DSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQ 2314
Query: 356 DLLSHEQ---KGRHQHGSHGGLDIVIIEQEDDSDRH 388
SHEQ +HGSH +Q DS RH
Sbjct: 2315 AASSHEQARSSAGERHGSHH-------QQSADSSRH 2343
Score = 39.7 bits (91), Expect = 0.005
Identities = 73/365 (20%), Positives = 127/365 (34%), Gaps = 68/365 (18%)
Query: 16 EKQAAVMGQKGGSKGRLPSEFSQFP---HGQ-----KGQHYSGQKGKQQTESKGSFSIQY 67
E+ + G++ GS + ++ S+ HGQ + + G G Q ++S+G
Sbjct: 3616 EQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSD 3675
Query: 68 TYHVDANDHDQSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSKGHFHRVV 127
T V A H Q+ QQ Q+ + GR +S ++V
Sbjct: 3676 TQSVSA--HGQAGPHQQ-----------------SHQESTRGRSAGRS-GRSGSFLYQVS 3715
Query: 128 IHHKGGKAHRGTQNPSQD--QGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGR 185
H + AH G PS QG+ SS++S ++E Q ++ G G
Sbjct: 3716 THEQSESAH-GRAGPSTGGRQGSRHEQARDSSRHSASQEG---------QDTIRG-HPGS 3764
Query: 186 KQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDK 245
++GG Q SY +Q ++ H H + R + S S + + +
Sbjct: 3765 RRGGRQGSY----------HEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETR 3814
Query: 246 LQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGV 305
+ S D H+ +H + S Q S RR + V
Sbjct: 3815 NEEQSGDGSRHS------GSRHHEASTQADSSRHSQ-----SGQGESAGSRRSRRQGSSV 3863
Query: 306 QKDVSQSSIYSQTEEKAQGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQKGR 365
+D + +E +++ S+ + +++ G G S +D SH Q
Sbjct: 3864 SQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRHPGSS------HRDTASHVQSSP 3917
Query: 366 HQHGS 370
Q S
Sbjct: 3918 VQSDS 3922
Score = 35.8 bits (81), Expect = 0.070
Identities = 33/149 (22%), Positives = 59/149 (39%), Gaps = 19/149 (12%)
Query: 41 HGQKGQHYSGQKGKQQTESKGSFSIQYTYHVDANDHDQSRKSQQYDLNALHKTTKSQRHL 100
H Q GQ S G +++ +GS S+ +A D R+S+ + S+ H
Sbjct: 3842 HSQSGQGESA--GSRRSRRQGS-SVSQDSDSEAYPEDSERRSE----------SASRNHH 3888
Query: 101 GGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYS 160
G S +++ RD + G HR H + + +++ G+ S S+ +S
Sbjct: 3889 GSS------REQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHS 3942
Query: 161 NTEERLWVHGLSKEQTSVSGAQKGRKQGG 189
+ R H S G ++ + Q G
Sbjct: 3943 GIQSRGSPHSSSSYHYQSEGTERQKGQSG 3971
>gi|171916097 repetin [Homo sapiens]
Length = 784
Score = 48.5 bits (114), Expect = 1e-05
Identities = 74/339 (21%), Positives = 118/339 (34%), Gaps = 31/339 (9%)
Query: 23 GQKGGSKGRLPSEFSQFPHGQKGQ--HYSGQKGKQ-------QTESKGSFSIQYTYHVDA 73
G G RL E ++GQ HY GQ +Q QT+ +G S
Sbjct: 268 GSYCGQSERLGQELGCGQTDRQGQSSHY-GQTDRQDQSYHYGQTDRQGQSS-------HY 319
Query: 74 NDHDQSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKGG 133
+ D+ +S Y + + Q H Q R S H + +G
Sbjct: 320 SQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGS----HYSQPNRQGQ 375
Query: 134 KAHRGTQNPSQDQGN---SPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGS 190
+H G Q +QDQ + + SS Y TE + S+ G+ G+
Sbjct: 376 SSHYG-QPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDRQG 434
Query: 191 QSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGS 250
QSS+ Q + N +T Q+ + Q + + H S+ +H K+
Sbjct: 435 QSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQD 494
Query: 251 KDIFSTQDELLVYNKNQHQTKNLNQDQQHG---RKANKISYQSSSTEERRLHYGENGVQK 307
+ Q + + + QT Q +G R+ Y + + HYG+ Q
Sbjct: 495 QSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQ- 553
Query: 308 DVSQSSIYSQTEEKAQGKSQIQAPNPKQEPWHGENAKGE 346
QSS Y QT+ + Q Q Q + ++ GE
Sbjct: 554 --GQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGE 590
Score = 39.7 bits (91), Expect = 0.005
Identities = 44/223 (19%), Positives = 91/223 (40%), Gaps = 26/223 (11%)
Query: 172 SKEQTSVSGAQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHS 231
S+++ GAQ + G + + + EE N + + + H Q + R+ H
Sbjct: 99 SQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQPERQDRDSHH 158
Query: 232 SKVQTSLCPAHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSS 291
+ + +H + + +D Q E + + Q++ +QD G+ K+S++S+
Sbjct: 159 GQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGK---KVSHKST 215
Query: 292 STEER----------------RLHYGEN----GVQKDVSQSSIYSQTEEKAQGKSQIQAP 331
S + + HYG++ + + Q+S ++QT ++ G Q+
Sbjct: 216 SGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQASHFNQTNQQKSGSYCGQSE 275
Query: 332 NPKQEPWHGE-NAKGESGQ--STNREQDLLSHEQKGRHQHGSH 371
QE G+ + +G+S T+R+ + Q R SH
Sbjct: 276 RLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSH 318
>gi|62122917 filaggrin family member 2 [Homo sapiens]
Length = 2391
Score = 48.1 bits (113), Expect = 1e-05
Identities = 82/371 (22%), Positives = 139/371 (37%), Gaps = 59/371 (15%)
Query: 16 EKQAAVMGQKGGSKGRLPSEFSQFPHGQKGQHYSGQKGKQQTESKGSFSIQYTYHVDAND 75
E+ GQ G + G HG G S Q+G + T +GS
Sbjct: 1386 ERHETTYGQTGEATG----------HGHSGHGQSTQRGSRTTGRRGS------------G 1423
Query: 76 HDQSRKSQQYDLNALHKTTKSQRH------LGGSQQLLHNKQEGRDHDKSKGHFHRVVIH 129
H +S S+ + + ++ Q H G S +H + G H ++ G R +
Sbjct: 1424 HSESSDSEVHSGGSHRPQSQEQTHGQAGSQHGESGSTVHGR-HGTTHGQT-GDTTRHAHY 1481
Query: 130 HKGGKAHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVH-GLSKEQTSVSGAQKGRKQG 188
H G + TQ S G SG S+ S++E VH G S + + Q G + G
Sbjct: 1482 HHG----KSTQRGSSTTGRRGSG---HSESSDSE----VHSGGSHTHSGHTHGQSGSQHG 1530
Query: 189 GSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQH 248
S+S ++ + + Q +T H GH Q + + + +TS + ++
Sbjct: 1531 ESES--IIHDRHRITHGQTGDT-TRHSYSGHEQ-TTQTGSRTTGRQRTSHSESTDSEVHS 1586
Query: 249 GSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQKD 308
G +++ +QH+ ++HG +I + + + G +
Sbjct: 1587 GGSHRPHSREHTYGQAGSQHEEPEFTVHERHGTTHGQIGDTTGHSHSGHGQSTQRGSRTT 1646
Query: 309 VSQSSIYSQT--EEKAQGKSQIQAPNPKQEPWHGENAKGESGQSTN--REQDLLSHEQKG 364
Q S +S++ E G S + HG+ A + GQS + E+ +H Q G
Sbjct: 1647 GRQRSSHSESSDSEVHSGVSHTHTGHT-----HGQ-AGSQHGQSESIVPERHGTTHGQTG 1700
Query: 365 ---RHQHGSHG 372
RH H HG
Sbjct: 1701 DTTRHAHYHHG 1711
Score = 42.4 bits (98), Expect = 8e-04
Identities = 88/379 (23%), Positives = 126/379 (33%), Gaps = 61/379 (16%)
Query: 18 QAAVMGQKGGSKGRLPSEFSQFP----HGQKGQHYSGQKGKQQTESKGSFSIQYT-YHVD 72
Q+A GQ G G+ S F Q GQH SG GS S Q + +
Sbjct: 816 QSAGFGQHGSGSGQ-SSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQH 874
Query: 73 ANDHDQSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKG 132
+ Q Q+ + + Q G Q + E R H S G G
Sbjct: 875 RSSSGQYSGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSG 934
Query: 133 GKAHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQS 192
H + + G SG G SS + HG Q+ SG + G S
Sbjct: 935 YGQHGSSSGQTFGFGQHRSGSGQSSGFGQ-------HGSGSGQS--SGFGQHESGSGKSS 985
Query: 193 SYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKL------ 246
+ + + S Q+ G+ Q+ SS QT+ H+
Sbjct: 986 GFGQHESRSSQSNYGQHGSGSSQSSGYGQH-------GSSSGQTTGFGQHRSSSGQYSGF 1038
Query: 247 -QHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGV 305
QHGS S+ QH T + G+ + Y+S S R+ YG++G
Sbjct: 1039 GQHGSGSDQSS-------GFGQHGTGS-------GQSSGFGQYESRS---RQSSYGQHG- 1080
Query: 306 QKDVSQSSIYSQ---TEEKAQGKSQIQAPNPKQEPWHGE--------NAKGESGQSTNRE 354
SQSS Y Q + G Q P Q G+ + G+ G T +
Sbjct: 1081 -SGSSQSSGYGQHGSNSGQTSGFGQ-HRPGSGQSSGFGQYGSGSGQSSGFGQHGSGTGKS 1138
Query: 355 QDLLSHE-QKGRHQHGSHG 372
HE + G+ +G HG
Sbjct: 1139 SGFAQHEYRSGQSSYGQHG 1157
Score = 42.0 bits (97), Expect = 0.001
Identities = 82/385 (21%), Positives = 132/385 (34%), Gaps = 36/385 (9%)
Query: 18 QAAVMGQKGGSKGRLPSEFSQFPH-------GQKGQHYSGQKGKQQTESKGSFSIQYTYH 70
Q++ GQ G G+ S F+Q + GQ G S G Q ES + + H
Sbjct: 1124 QSSGFGQHGSGTGK-SSGFAQHEYRSGQSSYGQHGTGSSQSSGCGQHESGSGPTTSFGQH 1182
Query: 71 VDANDHDQSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSKGHFHRVVIHH 130
V +D+ S S Q+ ++ T Q G Q + E + + +H
Sbjct: 1183 VSGSDNFSS--SGQHISDSGQSTGFGQYGSGSGQSTGLGQGESQQVESGS------TVHG 1234
Query: 131 KGGKAHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGS 190
+ H T N ++ +S SG+G S+Q + R Q+ S ++ K
Sbjct: 1235 RQETTHGQTINTTR---HSQSGQGQSTQTGSRVTR----RRRSSQSENSDSEVHSKVSHR 1287
Query: 191 QSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGS 250
S ++ T+ + T Q H Q R HS Q++ + Q S
Sbjct: 1288 HSEHI-HTQAGSHYPKSGSTVRRRQGTTHGQRGDTTRHGHSGHGQSTQTGSRTSGRQRFS 1346
Query: 251 KDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEER-RLHYGENGVQKDV 309
S + V++ H+ +Q+Q H + ++ S+ ER YG+ G
Sbjct: 1347 ---HSDATDSEVHSGVSHRPH--SQEQTHSQAGSQHGESESTVHERHETTYGQTGEATGH 1401
Query: 310 SQSSIYSQTE--EKAQGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQKGRHQ 367
S T+ + G+ H + Q Q H + G
Sbjct: 1402 GHSGHGQSTQRGSRTTGRRGSGHSESSDSEVHSGGSHRPQSQEQTHGQAGSQHGESGSTV 1461
Query: 368 HGSHGGLDIVIIEQEDDSDRHLAQH 392
HG HG Q D+ RH H
Sbjct: 1462 HGRHG----TTHGQTGDTTRHAHYH 1482
Score = 36.2 bits (82), Expect = 0.054
Identities = 76/350 (21%), Positives = 118/350 (33%), Gaps = 61/350 (17%)
Query: 41 HGQKGQHYSGQKGKQQTESKGSFSIQYTYHVDANDHDQSRKSQQYDLNALHKTTKSQRHL 100
HG G S Q+G + T + S +Y+ D+ H S S + +A +
Sbjct: 2007 HGHSGHGQSTQRGSRTTGRRASGHSEYS---DSEGH--SGVSHTHSGHAHGQAGSQHGES 2061
Query: 101 GGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYS 160
G S H G+ D ++ H + TQ S+ G SG S+ S
Sbjct: 2062 GSSVHERHGTTHGQTGDTTR---------HAHSGHGQSTQRGSRTAGRRGSG---HSESS 2109
Query: 161 NTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHY 220
++E VH S + R Q G S + + + + T+ H GH
Sbjct: 2110 DSE----VHSGVSHTHSGHTYGQARSQHGESGSAIHGRQGTIHGQTGDTTR--HGQSGHG 2163
Query: 221 QNVV-------EVREEHS----SKVQTSLCPAHQDKL--QHGSKDIFSTQDELLVYNKNQ 267
Q+ R HS S+V + P H Q GS+ S
Sbjct: 2164 QSTQTGSRTTGRQRSSHSESSDSEVHSEASPTHSGHTHSQAGSRHGQSGSSGHGRQGTTH 2223
Query: 268 HQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTEEKAQGKSQ 327
QT + + +G Y S+ R + S S ++S G Q
Sbjct: 2224 GQTGDTTRHAHYG-------YGQSTQRGSRTTGRRGSGHSESSDSEVHSWGSHTHSGHIQ 2276
Query: 328 IQAPNPKQEPW---HG--ENAKGESGQSTNREQDLLSHEQKGRHQHGSHG 372
QA + +++P HG E G++G +T RH H +G
Sbjct: 2277 GQAGSQQRQPGSTVHGRLETTHGQTGDTT-------------RHGHSGYG 2313
Score = 29.3 bits (64), Expect = 6.6
Identities = 88/366 (24%), Positives = 121/366 (33%), Gaps = 78/366 (21%)
Query: 18 QAAVMGQKGGSKGRLPSEFSQFPHGQKGQHYSG--QKGKQQTESKG-----SFSIQYTYH 70
Q++ GQ G G+ S F Q HG SG Q G +S G S S Q +Y
Sbjct: 488 QSSGFGQCGSGSGQ-SSGFGQ--HGSVSGQSSGFGQHGSVSGQSSGFGQHESRSRQSSYG 544
Query: 71 VDANDHDQSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSKGHF-HRVVIH 129
+ QS QY +T+ +H GS Q Q G +S G H
Sbjct: 545 QHGSGSSQSSGYGQY---GSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGSGSG 601
Query: 130 HKGGKAHRGTQNPSQDQGNSPSGKGISSQYSNTEER----LWVHGLSKEQTSVSGAQKGR 185
G +++ G SG SS Y R HG Q++ G Q G
Sbjct: 602 QSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFG-QYG- 659
Query: 186 KQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDK 245
G QSS Q S Q+ G Q+ E R HSS Q +
Sbjct: 660 -SGSGQSSGFGQ-----------HVSGSGQSSGFGQH--ESRSGHSSYGQHGFGSSQSSG 705
Query: 246 L-QHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENG 304
QHGS + QT Q + +++ S + + +G++G
Sbjct: 706 YGQHGS---------------SSGQTSGFGQHELSSGQSSSFGQHGSGSGQSS-GFGQHG 749
Query: 305 VQKDVSQSSIYSQTEEKAQGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQKG 364
QSS + Q E + SGQS+ + S + G
Sbjct: 750 --SGSGQSSGFGQHESR-------------------------SGQSSYGQHSSGSSQSSG 782
Query: 365 RHQHGS 370
QHGS
Sbjct: 783 YGQHGS 788
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 47.4 bits (111), Expect = 2e-05
Identities = 84/365 (23%), Positives = 121/365 (33%), Gaps = 58/365 (15%)
Query: 18 QAAVMGQKGGSKGRLPSEFSQFPHGQKGQHYSGQKGKQQTESKGSFSIQYTYHVDANDHD 77
Q++ GQ G S G+ S GQH SG +GS S Q H
Sbjct: 2495 QSSSCGQHGASSGQSSSH---------GQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSG- 2544
Query: 78 QSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAHR 137
SR+S Y RH GS + + Q G +S G H H
Sbjct: 2545 -SRQSPSYG-----------RHGSGSGRSSSSGQHGSGLGESSGFGH-----------HE 2581
Query: 138 GTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQ 197
+ S SG G SS Y R + S SG+ Q GS S
Sbjct: 2582 SSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSG 2641
Query: 198 TEELVANKQQRETKNSH-QNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFST 256
+ Q ++ H GH + + S ++S ++ +L H S +F
Sbjct: 2642 HGRQGSGSGQSPSRGRHGSGLGHSSSH---GQHGSGSGRSSSRGPYESRLGHSS--VFGQ 2696
Query: 257 QDE----LLVYNKNQHQTKNLNQDQQHGRKANKISY--QSSSTEERRLHYGENGVQKDVS 310
+ Y+++ + + QHG + + S Q S+ + YG G S
Sbjct: 2697 HESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRG--SGSS 2754
Query: 311 QSSIYSQTEEKAQGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQKGRHQHGS 370
QSS Y + Q HG + G S+ + S + G QHGS
Sbjct: 2755 QSSGYGR-----------HGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGS 2803
Query: 371 HGGLD 375
G D
Sbjct: 2804 GSGQD 2808
Score = 47.0 bits (110), Expect = 3e-05
Identities = 87/385 (22%), Positives = 130/385 (33%), Gaps = 51/385 (13%)
Query: 18 QAAVMGQKGGSKGRLPSEFSQFPHGQKGQHYSGQKGKQQTESKGSFSIQYTYHVDANDHD 77
QA+ GQ G+ S+ HG H+S Q T + S S Q+ +
Sbjct: 813 QASGFGQHESGSGQGYSQ-----HGSASGHFSSQGRHGSTSGQSSSSGQHD-----SSSG 862
Query: 78 QSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRD---------HDKSKGHFHRVVI 128
QS Q++ +A H + RH GS Q + Q G H G
Sbjct: 863 QSSSYGQHE-SASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGR 921
Query: 129 HHKG-----GKAHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQK 183
H G G H+ + S SG G SS Y R S++ S SG+
Sbjct: 922 HGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSS 981
Query: 184 GRKQGGSQSSYVL-QTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCP-- 240
Q GS S L + + Q G Q+ S +S P
Sbjct: 982 SYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYE 1041
Query: 241 ---AHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISY--QSSSTEE 295
H L H S + Y ++ + + + QHG + + S Q ++
Sbjct: 1042 SGSGHSSGLGHRE----SRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSG 1097
Query: 296 RRLHYGENGVQKDVSQSSIYSQTEEKAQGKSQIQAP-------NPKQEPWHGENAKGESG 348
+ +G++G SQSS Y + QG Q+P +Q P +G + G
Sbjct: 1098 QSSSHGQHG--SGSSQSSGYGR-----QGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGR 1150
Query: 349 QSTNREQDLLSHEQKGRHQHGSHGG 373
S++ + E G H S G
Sbjct: 1151 SSSSGQHGSGLGESSGFGHHESSSG 1175
Score = 45.8 bits (107), Expect = 7e-05
Identities = 87/407 (21%), Positives = 136/407 (33%), Gaps = 77/407 (18%)
Query: 17 KQAAVMGQKGGSKGRLPS------------EFSQFPHGQ-------KGQHYSGQK---GK 54
+Q+ GQ G G+ PS S P+G +G + SG G
Sbjct: 1461 RQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGL 1520
Query: 55 QQTESKGSFSIQYTYHVDANDHD-----------QSRKSQQYDLNALHKTTKSQRHLGGS 103
ES+ S Y H ++ H QS Q+ ++ ++ Q G S
Sbjct: 1521 GHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSS 1580
Query: 104 QQLLHNKQEGRDHDKSKGHFHRVVIHHKGGK--AHRGTQNPSQDQGNSPSGKGISSQYSN 161
Q + +Q G +S GH R + H S G SG G SS + +
Sbjct: 1581 QSSGYGRQ-GSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGH 1639
Query: 162 TEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQ 221
E + S SG G Q GS+S +++ +R +S + + Q
Sbjct: 1640 HESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQ--------SSRGERHGSSSRSSSRYGQ 1691
Query: 222 NVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGR 281
+ R+ Q S + +HGS H + + GR
Sbjct: 1692 HGSGSRQSSGHGRQGSGSGQSPSRGRHGSG--------------LGHSSSHGQHGSGSGR 1737
Query: 282 KANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQ------------TEEKAQGKSQI- 328
+++ Y+S S E+G SS YSQ G+S
Sbjct: 1738 SSSRGPYESRSGHSSVFGQHESGS----GHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTF 1793
Query: 329 --QAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQKGRHQHGSHGG 373
+ + Q HG++ G S S+ +Q S + R +HGS G
Sbjct: 1794 DQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSG 1840
Score = 44.3 bits (103), Expect = 2e-04
Identities = 79/360 (21%), Positives = 125/360 (34%), Gaps = 45/360 (12%)
Query: 19 AAVMGQKGGSKGRLPSEFSQFPHGQKGQHYSGQKGKQQTESKGSFSIQYTYHVDANDHDQ 78
++V GQ G S +SQ HG H+ Q T + S T+ + + Q
Sbjct: 1751 SSVFGQHESGSGH-SSAYSQ--HGSGSGHFCSQGQHGSTSGQSS-----TFDQEGSSTGQ 1802
Query: 79 SRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAHRG 138
S Q+ + ++ Q+ G Q + GR H GH H G
Sbjct: 1803 SSSHGQHGSGSSQSSSYGQQGSGSGQ----SPSRGR-HGSGSGHSSSYGQHGSGS----- 1852
Query: 139 TQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQT 198
S G SG G SS + + E W + S SG +Q GS+S +
Sbjct: 1853 --GWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRG 1910
Query: 199 EELVANKQQRETKNSH-----QNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDI 253
E+ ++ + H Q+ GH Q H S S P+ + +HGS
Sbjct: 1911 EQHGSSSGSSSSYGQHGSGSRQSLGHGQ--------HGSGSGQSPSPS---RGRHGSGS- 1958
Query: 254 FSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSS 313
Y + + + ++ + ++ S + + YG++G SS
Sbjct: 1959 -GQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSS-GYGQHG--SSSGHSS 2014
Query: 314 IYSQTEEKAQGKSQI---QAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQKGRHQHGS 370
+ Q A G+S + Q HG++ G S S Q S + G Q GS
Sbjct: 2015 THGQ-HGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGS 2073
Score = 43.9 bits (102), Expect = 3e-04
Identities = 86/407 (21%), Positives = 136/407 (33%), Gaps = 77/407 (18%)
Query: 17 KQAAVMGQKGGSKGRLPS------------EFSQFPHGQ-------KGQHYSGQ---KGK 54
+Q+ GQ G G+ PS S P+G +G + SG G
Sbjct: 1931 RQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGL 1990
Query: 55 QQTESKGSFSIQYTYHVDANDHD-----------QSRKSQQYDLNALHKTTKSQRHLGGS 103
ES+ S Y H ++ H QS Q+ ++ ++ Q G S
Sbjct: 1991 GHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSS 2050
Query: 104 QQLLHNKQEGRDHDKSKGHFHRVVIHHKGGK--AHRGTQNPSQDQGNSPSGKGISSQYSN 161
Q + +Q G +S GH R + H S G G G SS + +
Sbjct: 2051 QSSGYGRQ-GSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGH 2109
Query: 162 TEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQ 221
E + S SG G Q GS+S +++ +R +S + + Q
Sbjct: 2110 HESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQ--------SSRGERHGSSSGSSSRYGQ 2161
Query: 222 NVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGR 281
+ R+ Q S + +HGS + H + + GR
Sbjct: 2162 HGSGSRQSSGHGRQGSGSGHSPSRGRHGSG--------------SGHSSSHGQHGSGSGR 2207
Query: 282 KANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQ------------TEEKAQGKSQI- 328
+++ Y+S S E+G SS YSQ G+S
Sbjct: 2208 SSSRGPYESRSGHSSVFGQHESGS----GHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTF 2263
Query: 329 --QAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQKGRHQHGSHGG 373
+ + Q HG++ G S S+ +Q S + R +HGS G
Sbjct: 2264 DQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSG 2310
Score = 43.1 bits (100), Expect = 4e-04
Identities = 74/357 (20%), Positives = 119/357 (33%), Gaps = 39/357 (10%)
Query: 19 AAVMGQKGGSKGRLPSEFSQFPHGQKGQHYSGQKGKQQTESKGSFSIQYTYHVDANDHDQ 78
++V GQ G S +SQ HG H+ Q T + S T+ + + Q
Sbjct: 2221 SSVFGQHESGSGH-SSAYSQ--HGSGSGHFCSQGQHGSTSGQSS-----TFDQEGSSTGQ 2272
Query: 79 SRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAHRG 138
S Q+ + ++ Q+ G Q + GR H GH H G
Sbjct: 2273 SSSHGQHGSGSSQSSSYGQQGSGSGQ----SPSRGR-HGSGSGHSSSYGQHGSGS----- 2322
Query: 139 TQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQT 198
S G SG G SS + + E W + S SG +Q GS+S +
Sbjct: 2323 --GWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRG 2380
Query: 199 EELVANKQQRETKNSH-----QNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDI 253
E ++ + H Q+ GH Q H S S P+ + +HGS
Sbjct: 2381 ERHGSSSGSSSSYGQHGSGSRQSLGHGQ--------HGSGSGQSPSPS---RGRHGSGS- 2428
Query: 254 FSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSS 313
Y + + + ++ + ++ S + + YG++G S +
Sbjct: 2429 -GQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSS-GYGQHGSSSGHSSTH 2486
Query: 314 IYSQTEEKAQGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQKGRHQHGS 370
+ + Q HG++ G S S Q S + G Q GS
Sbjct: 2487 GQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGS 2543
Score = 41.2 bits (95), Expect = 0.002
Identities = 68/273 (24%), Positives = 92/273 (33%), Gaps = 53/273 (19%)
Query: 98 RHLGGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAHRGTQNPSQDQGNSPSGKGISS 157
+H GS Q N G +S G H+ + S SG G SS
Sbjct: 207 QHGSGSGQSSSNDTHGSGSGQSSGF-----------SQHKSSSGQSSGYSQHGSGSGHSS 255
Query: 158 QYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNK 217
Y HG Q+ S ++ R GS SSY + S Q+
Sbjct: 256 GYGQ-------HGSRSGQS--SRGERHRSSSGSSSSY------------GQHGSGSRQSL 294
Query: 218 GHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQ 277
GH + R+ S S QHGS +S Y QT Q +
Sbjct: 295 GHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRG--HYESGSGQTSGFGQHE 352
Query: 278 ----------QHGRKANKISYQS--SSTEERRLHYGENGVQKDVSQSSIYSQTEEKAQ-- 323
+HG + S Q ST + G++G QSS Y Q E ++
Sbjct: 353 SGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHG--SSSRQSSSYGQHESASRHS 410
Query: 324 -GKSQIQAPNPKQEPWHGENAKGESGQSTNREQ 355
G+ Q + Q P HG+ G SGQS + Q
Sbjct: 411 SGRGQ-HSSGSGQSPGHGQRGSG-SGQSPSSGQ 441
Score = 40.4 bits (93), Expect = 0.003
Identities = 75/359 (20%), Positives = 116/359 (32%), Gaps = 25/359 (6%)
Query: 23 GQKGGSKGRLPSEF---SQFPHGQK-GQHYSGQKGKQQTESKGSFSIQY-TYHVDANDHD 77
GQ G GR S S+ H GQH SG GS S + + +
Sbjct: 1259 GQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSG 1318
Query: 78 QSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQ-EGRDHDKSKGHFHRVVIHHKGGKAH 136
QS Q + ++ R G SQ + + G S+G H H
Sbjct: 1319 QSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQH 1378
Query: 137 RGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVL 196
S G SG G SS + + E W + S SG +Q GS+S
Sbjct: 1379 GSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSS 1438
Query: 197 QTEELVANKQQRETKNSH-----QNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSK 251
+ E ++ + H Q+ GH Q H S S P+ + +HGS
Sbjct: 1439 RGERHGSSSGSSSSYGQHGSGSRQSLGHGQ--------HGSGSGQSPSPS---RGRHGSG 1487
Query: 252 DIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQ 311
Y + + + ++ + ++ S + + YG++G S
Sbjct: 1488 S--GQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSS-GYGQHGSSSGHSS 1544
Query: 312 SSIYSQTEEKAQGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQKGRHQHGS 370
+ + + Q HG++ G S S Q S + G Q GS
Sbjct: 1545 THGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGS 1603
Score = 40.0 bits (92), Expect = 0.004
Identities = 74/365 (20%), Positives = 114/365 (31%), Gaps = 47/365 (12%)
Query: 18 QAAVMGQKGGSKGRLPSEFSQFPHGQKGQHYSGQKGKQQTESKGSFSIQYTYHVDANDHD 77
Q + GQ G+ S +S+ HG H S Q T + S S Q+ +
Sbjct: 344 QTSGFGQHESGSGQ-SSGYSK--HGSGSGHSSSQGQHGSTSGQASSSGQH-----GSSSR 395
Query: 78 QSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQ-EGRDHDKSKGHFHRVVIHHKGGKAH 136
QS Q++ + H + + Q G Q H ++ G S G H G
Sbjct: 396 QSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQ-------HGTGFGR 448
Query: 137 RGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSG--------AQKGRKQG 188
+ P SG G S HG +S G + +G +QG
Sbjct: 449 SSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQG 508
Query: 189 GSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQH 248
S S + ++Q G + R E S+ +S P +
Sbjct: 509 SSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRS 568
Query: 249 GSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQKD 308
S+ Y + L + +++ SS+ H G++G
Sbjct: 569 SSRG---------PYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTH-GQHGSTS- 617
Query: 309 VSQSSIYSQTEEKAQGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQKGRHQH 368
QSS Q Q HG++ G S S +Q S + R +H
Sbjct: 618 -GQSSSCGQ-----------HGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRH 665
Query: 369 GSHGG 373
GS G
Sbjct: 666 GSDFG 670
Score = 38.9 bits (89), Expect = 0.008
Identities = 83/381 (21%), Positives = 128/381 (33%), Gaps = 68/381 (17%)
Query: 18 QAAVMGQKGGSKGRLPSEFSQFPHGQKGQHYSGQKGKQQTESKGSFSIQYTYHVDANDHD 77
Q++ GQ G S G+ S GQH SG +GS S Q H
Sbjct: 1085 QSSSCGQHGASSGQSSSH---------GQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSG- 1134
Query: 78 QSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAHR 137
SR+S Y RH GS + + Q G +S G H H
Sbjct: 1135 -SRQSPSYG-----------RHGSGSGRSSSSGQHGSGLGESSGFGH-----------HE 1171
Query: 138 GTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQ 197
+ S SG G SS Y R + S SG+ Q GS S
Sbjct: 1172 SSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGS----- 1226
Query: 198 TEELVANKQQRETKNSHQNKGHYQNVVEVREEH----SSKVQTSLCPAHQDKLQHGSKDI 253
+ + +Q ++G + + + H S ++S ++ + H S +
Sbjct: 1227 -RQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSS--V 1283
Query: 254 F----STQDELLVYNKNQHQTKNLNQDQQHGRKANKISY--QSSSTEERRLHYGENGVQK 307
F S Y+++ + + QHG + + S Q S+ + YG G
Sbjct: 1284 FGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRG--S 1341
Query: 308 DVSQSSIYSQ-----TEEKAQGKSQIQAPNPKQEPWHG-----ENAKGESGQSTNREQDL 357
SQSS Y + + ++G+ + + HG ++ G G + +
Sbjct: 1342 GSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGF 1401
Query: 358 LSHE-----QKGRHQHGSHGG 373
HE G QHGS G
Sbjct: 1402 GHHESSSWQSSGCTQHGSGSG 1422
Score = 29.6 bits (65), Expect = 5.0
Identities = 39/172 (22%), Positives = 60/172 (34%), Gaps = 28/172 (16%)
Query: 202 VANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQDELL 261
V+ + R+ + HQ + E + + SS +S D + E +
Sbjct: 96 VSGSKLRDDTHQHQEEQEETEKEENKRQESSFSHSSWSAGENDSYSRNVRGSLKPGTESI 155
Query: 262 VYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTEEK 321
++ L+ + + N S QSSS YGE D QSS Q
Sbjct: 156 --------SRRLSFQRDFSGQHNSYSGQSSS-------YGEQN--SDSHQSSGRGQC--- 195
Query: 322 AQGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQKGRHQHGSHGG 373
G Q+PN +G++ G S+N S + G QH S G
Sbjct: 196 --GSGSGQSPN------YGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSG 239
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 43.1 bits (100), Expect = 4e-04
Identities = 50/296 (16%), Positives = 125/296 (42%), Gaps = 19/296 (6%)
Query: 70 HVDANDHDQSR-KSQQYDLNALHKTTKSQRHLGG-SQQLLHNKQEGRDHD------KSKG 121
H +H ++R ++++ L+ + + ++S+ H G SQ + GR H+ K +
Sbjct: 305 HSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERS 364
Query: 122 HFHRVVIHHKGGKAHRGTQNPSQDQGNSPSGKGISSQ-YSNTEERLWVHGLSKEQTSVSG 180
H H + + HRG+ +P ++ G S SG + +S + S+ ++
Sbjct: 365 HSHSRSSSKE--RDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKA 422
Query: 181 AQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCP 240
+ R + +++ ++ + + +++ ++ + H ++ + S+ ++
Sbjct: 423 RDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKE 482
Query: 241 AHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHY 300
+L SK+ + + Q+++ ++++ H R +S S E +R
Sbjct: 483 RDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRS------RSPSKERQRRQS 536
Query: 301 GENGVQKDVSQSSIYSQTEEKAQGKSQIQAPNPKQEPWHGENAKGESGQSTNREQD 356
++D SQS S +EE+ +S+ + + W + + E QS + ++
Sbjct: 537 RSPNKERDRSQSR--SPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEE 590
Score = 34.3 bits (77), Expect = 0.20
Identities = 52/254 (20%), Positives = 104/254 (40%), Gaps = 28/254 (11%)
Query: 133 GKAHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQ---TSVSGAQKGRKQGG 189
G A R SQ +G+ G + LSK+ SG + +
Sbjct: 153 GMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAV 212
Query: 190 SQSSYVLQTEELVANKQQRET---KNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKL 246
+ S+ QT + +K++ + +S + K + Q ++ RE+ S + S ++
Sbjct: 213 TPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQA 272
Query: 247 QHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQ 306
S+ +Q +++ ++++ +Q + H R + ++ S R G
Sbjct: 273 STRSRPQSHSQ------SRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGI---- 322
Query: 307 KDVSQSSIYSQTEEKAQGKSQIQAPNPKQ---EPWHGENAKGES---GQSTNREQD---- 356
+SQ +SQ+ ++GKSQ Q+ P++ W +K S +S+++E+D
Sbjct: 323 --LSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGS 380
Query: 357 LLSHEQKGRHQHGS 370
++ GR Q GS
Sbjct: 381 SSPRKESGRSQSGS 394
Score = 32.0 bits (71), Expect = 1.0
Identities = 62/324 (19%), Positives = 114/324 (35%), Gaps = 19/324 (5%)
Query: 42 GQKGQHYSGQKGKQQTESK----GSFSIQYTYHVDANDHDQSRKSQQYDLNALHKTTKSQ 97
G+ Q S KGK Q +S+ G H SR S + H+ + S
Sbjct: 327 GRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSK---ERDHRGSSSP 383
Query: 98 RHLGG-SQQLLHNKQEGRDHDKSKG-----HFHRVVIHHKGGKAHRG-TQNPSQDQGNSP 150
R G SQ NKQ RDH +S+ R +K R + N ++D S
Sbjct: 384 RKESGRSQSGSPNKQ--RDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSR 441
Query: 151 SG-KGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQTEELVANKQQRE 209
S K S + + H S+ + R + L + + ++
Sbjct: 442 SPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSR 501
Query: 210 TKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQDELLVYNKNQHQ 269
+ + + ++ + R+ S+ + Q + + +D ++ Q +
Sbjct: 502 SPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSR 561
Query: 270 TKNLNQDQQHGRKANKISY--QSSSTEERRLHYGENGVQKDVSQSSIYSQTEEKAQGKSQ 327
+ + +D++ R +K QS S+ E R H K S + ++EKA +S+
Sbjct: 562 SPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSR 621
Query: 328 IQAPNPKQEPWHGENAKGESGQST 351
+ + + + QST
Sbjct: 622 TPSKEGNHSQSRTSSKESDPSQST 645
>gi|4504487 histidine rich calcium binding protein precursor [Homo
sapiens]
Length = 699
Score = 42.7 bits (99), Expect = 6e-04
Identities = 62/345 (17%), Positives = 119/345 (34%), Gaps = 56/345 (16%)
Query: 45 GQHYSGQKGKQQTESKGSFSIQYTYHVDANDHDQSRKSQQYDLNALHKTTKSQRHLGGSQ 104
G H+ G + Q + D +D D D ++ ++ RH G
Sbjct: 230 GHHHHGPSHRHQGHEE-----------DDDDDDDDDDDDDDDDVSIEYRHQAHRHQG--- 275
Query: 105 QLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYSNTEE 164
H +E D D S GH HR H ++H N D +S++Y +
Sbjct: 276 ---HGIEE--DEDVSDGHHHRDPSHRH--RSHEEDDNDDDD---------VSTEYGHQAH 319
Query: 165 RLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVV 224
R H +E +VSG + + E+ + T+ HQ H + +
Sbjct: 320 RHQDHR-KEEVEAVSGEHHHHVPDHRHQGHRDEEED-----EDVSTERWHQGPQHVHHGL 373
Query: 225 EVREEHSSKVQTSL---CPAHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGR 281
EE ++ +HQ + ++ F + + V + + H+ ++
Sbjct: 374 VDEEEEEEEITVQFGHYVASHQPRGHKSDEEDFQDEYKTEVPHHHHHRVPREEDEEVSAE 433
Query: 282 KANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTEEKAQGKSQIQAPNPKQEPWHGE 341
++ S ++ +G+ G K++S + + +S ++
Sbjct: 434 LGHQAPSHRQSHQDEETGHGQRGSIKEMSH---HPPGHTVVKDRSHLR------------ 478
Query: 342 NAKGESGQSTNREQDLLSHEQKGRHQHGSHGGLDIVIIEQEDDSD 386
K +S + +E+D SHE+ G +QED+ D
Sbjct: 479 --KDDSEEEKEKEEDPGSHEEDDESSEQGEKGTHHGSRDQEDEED 521
>gi|62244004 modulator of estrogen induced transcription isoform b
[Homo sapiens]
Length = 1016
Score = 41.2 bits (95), Expect = 0.002
Identities = 63/319 (19%), Positives = 119/319 (37%), Gaps = 49/319 (15%)
Query: 72 DANDHDQSRKSQQYDLNALHKTTKSQRHLGG---SQQLLHNKQEGRDHDKSKGHFHR-VV 127
DA ++S+ Y++NA HK K + + G ++ + ++ DK K +
Sbjct: 266 DAIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPS 325
Query: 128 IHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYS----NTEERLWVHGLSKEQTSVSGAQK 183
G+A ++ + +S KG +S S ++ + +WV GLS +
Sbjct: 326 STGASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNL 385
Query: 184 GRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQ 243
K G S+ V+ N+ +V + SS + S C AH
Sbjct: 386 FGKYGKVLSAKVV--------------TNARSPGAKCYGIVTM----SSSTEVSRCIAHL 427
Query: 244 DKLQ-HGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGE 302
+ + HG +L+ K + +++ K++ S R +
Sbjct: 428 HRTELHG---------QLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQ 478
Query: 303 NGVQKDVSQSSIYSQTEEKAQGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQ 362
V+K+ +SS S+ +E K G++ K ++G S + + E+
Sbjct: 479 ASVKKEEKRSSEKSEKKESKDTKK-----------IEGKDEKNDNGASGQTSESIKKSEE 527
Query: 363 KGRHQHGSHGGLDIVIIEQ 381
K R S G +VI++Q
Sbjct: 528 KKRISSKSPG--HMVILDQ 544
>gi|63176611 modulator of estrogen induced transcription isoform a
[Homo sapiens]
Length = 1034
Score = 41.2 bits (95), Expect = 0.002
Identities = 63/319 (19%), Positives = 119/319 (37%), Gaps = 49/319 (15%)
Query: 72 DANDHDQSRKSQQYDLNALHKTTKSQRHLGG---SQQLLHNKQEGRDHDKSKGHFHR-VV 127
DA ++S+ Y++NA HK K + + G ++ + ++ DK K +
Sbjct: 284 DAIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPS 343
Query: 128 IHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYS----NTEERLWVHGLSKEQTSVSGAQK 183
G+A ++ + +S KG +S S ++ + +WV GLS +
Sbjct: 344 STGASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNL 403
Query: 184 GRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQ 243
K G S+ V+ N+ +V + SS + S C AH
Sbjct: 404 FGKYGKVLSAKVV--------------TNARSPGAKCYGIVTM----SSSTEVSRCIAHL 445
Query: 244 DKLQ-HGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGE 302
+ + HG +L+ K + +++ K++ S R +
Sbjct: 446 HRTELHG---------QLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQ 496
Query: 303 NGVQKDVSQSSIYSQTEEKAQGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQ 362
V+K+ +SS S+ +E K G++ K ++G S + + E+
Sbjct: 497 ASVKKEEKRSSEKSEKKESKDTKK-----------IEGKDEKNDNGASGQTSESIKKSEE 545
Query: 363 KGRHQHGSHGGLDIVIIEQ 381
K R S G +VI++Q
Sbjct: 546 KKRISSKSPG--HMVILDQ 562
>gi|190194423 SPARC-like 1 [Homo sapiens]
Length = 664
Score = 40.4 bits (93), Expect = 0.003
Identities = 46/258 (17%), Positives = 103/258 (39%), Gaps = 18/258 (6%)
Query: 149 SPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQTEELVANKQQR 208
+P I S + EE +S E S A+K + S+ E+ ++ Q+
Sbjct: 36 APDNTAIPSLRAEAEENEKETAVSTEDDSHHKAEKSSVLKSKEESHEQSAEQGKSSSQEL 95
Query: 209 ETKNSHQNKGHY---------QNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFST--Q 257
K+ + GH + ++++E+ S + L + D L G + Q
Sbjct: 96 GLKDQEDSDGHLSVNLEYAPTEGTLDIKEDMSEPQEKKL-SENTDFLAPGVSSFTDSNQQ 154
Query: 258 DELLVYNKNQHQTKNLNQDQ--QHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIY 315
+ + +NQ Q +N + Q + + + + Q + ++ + GE +K+ + +
Sbjct: 155 ESITKREENQEQPRNYSHHQLNRSSKHSQGLRDQGNQEQDPNISNGEEEEEKEPGEVGTH 214
Query: 316 SQTEEKAQGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQKGRHQHGSHGGLD 375
+ +E+ + A N KQE +N + + + + +S Q+ G+ D
Sbjct: 215 NDNQERKTELPREHA-NSKQEE---DNTQSDDILEESDQPTQVSKMQEDEFDQGNQEQED 270
Query: 376 IVIIEQEDDSDRHLAQHL 393
E E+++ ++ +H+
Sbjct: 271 NSNAEMEEENASNVNKHI 288
>gi|190341024 SPARC-like 1 [Homo sapiens]
Length = 664
Score = 40.4 bits (93), Expect = 0.003
Identities = 46/258 (17%), Positives = 103/258 (39%), Gaps = 18/258 (6%)
Query: 149 SPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQTEELVANKQQR 208
+P I S + EE +S E S A+K + S+ E+ ++ Q+
Sbjct: 36 APDNTAIPSLRAEAEENEKETAVSTEDDSHHKAEKSSVLKSKEESHEQSAEQGKSSSQEL 95
Query: 209 ETKNSHQNKGHY---------QNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFST--Q 257
K+ + GH + ++++E+ S + L + D L G + Q
Sbjct: 96 GLKDQEDSDGHLSVNLEYAPTEGTLDIKEDMSEPQEKKL-SENTDFLAPGVSSFTDSNQQ 154
Query: 258 DELLVYNKNQHQTKNLNQDQ--QHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIY 315
+ + +NQ Q +N + Q + + + + Q + ++ + GE +K+ + +
Sbjct: 155 ESITKREENQEQPRNYSHHQLNRSSKHSQGLRDQGNQEQDPNISNGEEEEEKEPGEVGTH 214
Query: 316 SQTEEKAQGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQKGRHQHGSHGGLD 375
+ +E+ + A N KQE +N + + + + +S Q+ G+ D
Sbjct: 215 NDNQERKTELPREHA-NSKQEE---DNTQSDDILEESDQPTQVSKMQEDEFDQGNQEQED 270
Query: 376 IVIIEQEDDSDRHLAQHL 393
E E+++ ++ +H+
Sbjct: 271 NSNAEMEEENASNVNKHI 288
>gi|50409738 SRp25 nuclear protein isoform 3 [Homo sapiens]
Length = 352
Score = 40.4 bits (93), Expect = 0.003
Identities = 43/202 (21%), Positives = 82/202 (40%), Gaps = 29/202 (14%)
Query: 171 LSKEQTSVSGAQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEH 230
L K + +SG Q GR +G V ++++ +++ + +G E R++
Sbjct: 105 LEKARGGLSGPQGGRARGAMAH---------VGSRKRSRSRSRSRGRGS-----EKRKKK 150
Query: 231 SSKVQTSLCPAHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQS 290
S K + C A + G K + E K + +T++ + ++ S S
Sbjct: 151 SRKDTSRNCSASTSQ---GRKASTAPGAEERSKQKARRRTRSSSSSSSSSSSSSSSSSSS 207
Query: 291 SSTE-----ERRLHYGENGVQKDVSQSSIYSQTEEKAQGKSQIQAPNPKQEPWHGENAKG 345
SS+ ++R Y + +K + + + +EKA+ + P P + WH +
Sbjct: 208 SSSSSSDGRKKRGKYKDKRRKKKKKRKKLKKKGKEKAEAQQVEALPGPSLDQWHRSAGEE 267
Query: 346 ESGQSTNREQDLLSHEQKGRHQ 367
E G +L+ EQK R Q
Sbjct: 268 EDG-------PVLTDEQKSRIQ 282
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 39.7 bits (91), Expect = 0.005
Identities = 42/231 (18%), Positives = 89/231 (38%), Gaps = 22/231 (9%)
Query: 163 EERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQN 222
+E+LW H +EQ + Q + + E++ Q++E K Q K +
Sbjct: 664 KEKLWEHEKMQEQEKMQ----------EQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEE 713
Query: 223 VVEVRE------EHSSKVQTSLCPAHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQD 276
+ RE E + Q ++K+Q ++++ ++++ + + + L +
Sbjct: 714 SMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQ 773
Query: 277 QQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTEEKAQGKSQIQAPNPKQE 336
++ + K+ Q E+ + +K Q EEK +G+ + ++
Sbjct: 774 KEKLWEHEKMQEQEKIWEQEEKMRDQE--EKMRGQEEKMRGQEEKMRGQEEKMWGQEEKM 831
Query: 337 PWHGENAKGES----GQSTNREQDLLSHEQKGRHQHGSHGGLDIVIIEQED 383
E G+ GQ E+ + E+K R Q G + + EQE+
Sbjct: 832 WGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEE 882
>gi|50409756 SRp25 nuclear protein isoform 1 [Homo sapiens]
Length = 360
Score = 39.7 bits (91), Expect = 0.005
Identities = 39/202 (19%), Positives = 80/202 (39%), Gaps = 21/202 (10%)
Query: 171 LSKEQTSVSGAQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEH 230
L K + +SG Q GR +G V ++++ +++ + +G + + R++
Sbjct: 105 LEKARGGLSGPQGGRARGAMAH---------VGSRKRSRSRSRSRGRGSEKRKKKSRKDT 155
Query: 231 SSKVQTSLCPAHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQS 290
S S + G++ S K + +T++ + ++ S S
Sbjct: 156 SRNCSASTSQGRKASTAPGAEASPSPCITERSKQKARRRTRSSSSSSSSSSSSSSSSSSS 215
Query: 291 SSTE-----ERRLHYGENGVQKDVSQSSIYSQTEEKAQGKSQIQAPNPKQEPWHGENAKG 345
SS+ ++R Y + +K + + + +EKA+ + P P + WH +
Sbjct: 216 SSSSSSDGRKKRGKYKDKRRKKKKKRKKLKKKGKEKAEAQQVEALPGPSLDQWHRSAGEE 275
Query: 346 ESGQSTNREQDLLSHEQKGRHQ 367
E G +L+ EQK R Q
Sbjct: 276 EDG-------PVLTDEQKSRIQ 290
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 38.9 bits (89), Expect = 0.008
Identities = 68/347 (19%), Positives = 132/347 (38%), Gaps = 54/347 (15%)
Query: 33 PSEFSQFPHGQKGQHYSGQKGKQQTESKGSFSIQYTYHVDANDHDQSR----KSQQY--- 85
P+E ++ K + GQKGK+Q SF + ++ D + K + Y
Sbjct: 83 PTENNEEEFTSKDKKKKGQKGKKQ-----SFDDNDSEELEDKDSKSKKTAKPKVEMYSGS 137
Query: 86 ----DLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAHRGTQN 141
D N L K K G Q + K +G + D+ + R N
Sbjct: 138 DDDDDFNKLPKKAK------GKAQKSNKKWDGSEEDEDNSKKIK----------ERSRIN 181
Query: 142 PSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQT-EE 200
S + G+ S ++ + + G K Q + G +S+ ++T +
Sbjct: 182 SSGESGDE------SDEFLQSRK-----GQKKNQKNKPGPNIESGNEDDDASFKIKTVAQ 230
Query: 201 LVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGS-KDIFSTQDE 259
A K++RE K + K + + E E + K S Q K + + K +
Sbjct: 231 KKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTG 290
Query: 260 LLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTE 319
++ ++ + +T +D G K K + +E + E +K S++++ + E
Sbjct: 291 VIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEK----EKEKKKGPSKATVKAMQE 346
Query: 320 EKAQGKSQIQAPNPKQEPWHGENAKG-ESGQSTNREQDLLSHEQKGR 365
A+ K + + ++E E K E ++ +E++ L E++ R
Sbjct: 347 ALAKLKEEEERQKREEE----ERIKRLEELEAKRKEEERLEQEKRER 389
>gi|7706635 cornulin [Homo sapiens]
Length = 495
Score = 38.5 bits (88), Expect = 0.011
Identities = 52/237 (21%), Positives = 90/237 (37%), Gaps = 25/237 (10%)
Query: 44 KGQHYSGQKGKQ---------------QTESKGSFSIQYTYHVDANDHDQSRKSQQYDLN 88
KGQHY G +Q Q ++ GS + +Y A Q R S Q L+
Sbjct: 128 KGQHYEGSSHRQSQQGSRGQNRPGVQTQGQATGSAWVS-SYDRQAESQSQERISPQIQLS 186
Query: 89 A-LHKTTKSQRHLGGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAHRG-TQNPSQDQ 146
+T K+ + +++ + ++ + H + G + G TQ QD
Sbjct: 187 GQTEQTQKAGEGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDS 246
Query: 147 GNSPSGKGISSQYSNTEER--LWVHGLSKEQTS--VSGAQKGRKQGGSQSSYVLQTEELV 202
+ +Q + ++ HG + QTS V+G + Q G+ + QT E
Sbjct: 247 SHQTGRTSKQTQEATNDQNRGTETHGQGRSQTSQAVTGGH-AQIQAGTHTQTPTQTVEQD 305
Query: 203 ANKQQRETKNSHQNKGHYQN-VVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQD 258
++ Q T Q + QN E+ + S+ ++ H ++Q GS QD
Sbjct: 306 SSHQTGSTSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGH-TQIQAGSHTETVEQD 361
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 38.1 bits (87), Expect = 0.014
Identities = 51/213 (23%), Positives = 82/213 (38%), Gaps = 26/213 (12%)
Query: 155 ISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQTEELVANKQQRETKNSH 214
+ S++ ER H ++T A+ K QS ++ E Q ++N
Sbjct: 1382 LQSEHDTLLER---HNKMLQETVSKEAELREKLCSIQSENMMMKSEHTQTVSQLTSQNEV 1438
Query: 215 QNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQDELLVYN--KNQHQTKN 272
V ++EEH V+T Q +L +F ++E + +Q KN
Sbjct: 1439 LRNSFRDQVRHLQEEHRKTVETL-----QQQLSKMEAQLFQLKNEPTTRSPVSSQQSLKN 1493
Query: 273 LNQDQQHGRKANKISYQSSSTEERRLHYG-ENGVQKDVSQSSIYSQTEEKAQGKSQIQAP 331
L + R+ + T R G E + VS +S Y+Q+ E+ + +P
Sbjct: 1494 LRE-----RRNTDLPLLDMHTVTREEGEGMETTDTESVSSASTYTQSLEQL-----LNSP 1543
Query: 332 NPKQEP--WHGENAKGESGQ---STNREQDLLS 359
K EP WH E K E Q ST + D L+
Sbjct: 1544 ETKLEPPLWHAEFTKEELVQKLSSTTKSADHLN 1576
>gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]
Length = 592
Score = 38.1 bits (87), Expect = 0.014
Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 23/176 (13%)
Query: 140 QNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQTE 199
Q+ + Q S G S Y + +G + + + G SQS Y
Sbjct: 9 QSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGYSQSYG 68
Query: 200 ELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQ-- 257
KQ ++ + N+G QN+ SS Q P++ D+ +G +D + Q
Sbjct: 69 GYENQKQSSYSQQPYNNQGQQQNM------ESSGSQGGRAPSY-DQPDYGQQDSYDQQSG 121
Query: 258 --------DELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERR--LHYGEN 303
DE Y++ QH + + NQ H ++ N Y + ++RR YGE+
Sbjct: 122 YDQHQGSYDEQSNYDQ-QHDSYSQNQQSYHSQREN---YSHHTQDDRRDVSRYGED 173
Score = 30.8 bits (68), Expect = 2.3
Identities = 29/144 (20%), Positives = 63/144 (43%), Gaps = 10/144 (6%)
Query: 16 EKQAAVMGQKGGSKGRLPSEFSQFPHGQKGQHYSGQKGKQQTESKGSFSIQYTY--HVDA 73
+ Q+ GG + + S +SQ P+ +GQ Q+ + + S+G + Y +
Sbjct: 58 QSQSGYSQSYGGYENQKQSSYSQQPYNNQGQ----QQNMESSGSQGGRAPSYDQPDYGQQ 113
Query: 74 NDHDQSRKSQQYDLNALHKTTKSQRH--LGGSQQLLHNKQEGRDHDKSKGHFHRVVIHHK 131
+ +DQ Q+ + ++ Q+H +QQ H+++E H ++ V + +
Sbjct: 114 DSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSH-HTQDDRRDVSRYGE 172
Query: 132 GGKAHRGTQNPSQDQGN-SPSGKG 154
+ + G+Q + +G G+G
Sbjct: 173 DNRGYGGSQGGGRGRGGYDKDGRG 196
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 37.7 bits (86), Expect = 0.019
Identities = 46/274 (16%), Positives = 113/274 (41%), Gaps = 32/274 (11%)
Query: 104 QQLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYSNTE 163
++ +H++++ + +K H+ K HR Q+ ++ + + ++ ++S
Sbjct: 94 KEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSR-R 152
Query: 164 ERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNV 223
ER + L +++ ++ +K+ Q + EE ++ R ++H
Sbjct: 153 ERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHR------- 205
Query: 224 VEVREEHSSKVQTS-------LCPAHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQD 276
+RE++S KV+ S P + +L G K + ++E + ++++
Sbjct: 206 -TMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPV---KEEKMEERDLLSDLQDISDS 261
Query: 277 QQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTEEKAQGKSQIQAPNPKQE 336
++ A S +S S E E +++ + S ++EE+ + + + +E
Sbjct: 262 ERKTSSAESSSAESGSGSEEE----EEEEEEEEEEGSTSEESEEEEEEEEE-------EE 310
Query: 337 PWHGENAKGESGQSTNR--EQDLLSHEQKGRHQH 368
G N++ S QS E+++ E++ H
Sbjct: 311 EETGSNSEEASEQSAEEVSEEEMSEDEERENENH 344
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 37.7 bits (86), Expect = 0.019
Identities = 46/274 (16%), Positives = 113/274 (41%), Gaps = 32/274 (11%)
Query: 104 QQLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYSNTE 163
++ +H++++ + +K H+ K HR Q+ ++ + + ++ ++S
Sbjct: 60 KEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSR-R 118
Query: 164 ERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNV 223
ER + L +++ ++ +K+ Q + EE ++ R ++H
Sbjct: 119 ERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHR------- 171
Query: 224 VEVREEHSSKVQTS-------LCPAHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQD 276
+RE++S KV+ S P + +L G K + ++E + ++++
Sbjct: 172 -TMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPV---KEEKMEERDLLSDLQDISDS 227
Query: 277 QQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTEEKAQGKSQIQAPNPKQE 336
++ A S +S S E E +++ + S ++EE+ + + + +E
Sbjct: 228 ERKTSSAESSSAESGSGSEEE----EEEEEEEEEEGSTSEESEEEEEEEEE-------EE 276
Query: 337 PWHGENAKGESGQSTNR--EQDLLSHEQKGRHQH 368
G N++ S QS E+++ E++ H
Sbjct: 277 EETGSNSEEASEQSAEEVSEEEMSEDEERENENH 310
>gi|50409691 SRp25 nuclear protein isoform 4 [Homo sapiens]
Length = 338
Score = 37.7 bits (86), Expect = 0.019
Identities = 39/197 (19%), Positives = 76/197 (38%), Gaps = 30/197 (15%)
Query: 171 LSKEQTSVSGAQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEH 230
L K + +SG Q GR +G V ++++ +++ + +G E R++
Sbjct: 105 LEKARGGLSGPQGGRARGAMAH---------VGSRKRSRSRSRSRGRGS-----EKRKKK 150
Query: 231 SSKVQTSLCPAHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQS 290
S K + C A + + K T+ + + + ++ S S
Sbjct: 151 SRKDTSRNCSASTSQERSKQKARRRTRSS---------SSSSSSSSSSSSSSSSSSSSSS 201
Query: 291 SSTEERRLHYGENGVQKDVSQSSIYSQTEEKAQGKSQIQAPNPKQEPWHGENAKGESGQS 350
S ++R Y + +K + + + +EKA+ + P P + WH + E G
Sbjct: 202 SDGRKKRGKYKDKRRKKKKKRKKLKKKGKEKAEAQQVEALPGPSLDQWHRSAGEEEDG-- 259
Query: 351 TNREQDLLSHEQKGRHQ 367
+L+ EQK R Q
Sbjct: 260 -----PVLTDEQKSRIQ 271
>gi|50409707 SRp25 nuclear protein isoform 2 [Homo sapiens]
Length = 341
Score = 37.7 bits (86), Expect = 0.019
Identities = 39/197 (19%), Positives = 76/197 (38%), Gaps = 30/197 (15%)
Query: 171 LSKEQTSVSGAQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEH 230
L K + +SG Q GR +G V ++++ +++ + +G E R++
Sbjct: 105 LEKARGGLSGPQGGRARGAMAH---------VGSRKRSRSRSRSRGRGS-----EKRKKK 150
Query: 231 SSKVQTSLCPAHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQS 290
S K + C A + + K T+ + + + ++ S S
Sbjct: 151 SRKDTSRNCSASTSQERSKQKARRRTRSS---------SSSSSSSSSSSSSSSSSSSSSS 201
Query: 291 SSTEERRLHYGENGVQKDVSQSSIYSQTEEKAQGKSQIQAPNPKQEPWHGENAKGESGQS 350
S ++R Y + +K + + + +EKA+ + P P + WH + E G
Sbjct: 202 SDGRKKRGKYKDKRRKKKKKRKKLKKKGKEKAEAQQVEALPGPSLDQWHRSAGEEEDG-- 259
Query: 351 TNREQDLLSHEQKGRHQ 367
+L+ EQK R Q
Sbjct: 260 -----PVLTDEQKSRIQ 271
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 37.4 bits (85), Expect = 0.024
Identities = 35/181 (19%), Positives = 68/181 (37%), Gaps = 10/181 (5%)
Query: 169 HGLSKEQTSVSGAQKGRKQGG------SQSSYVLQTEELVANKQQRETKNSHQNKGHYQN 222
H +++ V +KG+KQ ++ +L ++ ++K S ++
Sbjct: 427 HKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMKSSCDRERSSR 486
Query: 223 VVEVREEHSSKVQTSLCPAH-QDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGR 281
+ HSSK S Q L H S+D + ++ Y++ +++ ++ H R
Sbjct: 487 SSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSR 546
Query: 282 KANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTEEKAQGKSQIQAPNPKQEPWHGE 341
+K S S +R +K SQ S + + + Q N +P E
Sbjct: 547 SRSKSRSSSKSGHRKR---ASKSPRKTASQLSENKPVKTEPLRATMAQNENVVVQPVVAE 603
Query: 342 N 342
N
Sbjct: 604 N 604
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 37.4 bits (85), Expect = 0.024
Identities = 41/219 (18%), Positives = 83/219 (37%), Gaps = 11/219 (5%)
Query: 140 QNPSQDQGNSPSGKGI--SSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQ 197
Q+P D+ P G S Q E+ +W ++ + ++ RK+ + + +
Sbjct: 416 QHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEE 475
Query: 198 TEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQ 257
+ ++ + + E+RE K + +++ Q K+ +
Sbjct: 476 QRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDR 535
Query: 258 DELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQ 317
+ + Q + K L ++Q+ R+ K Q E R E +QK Q
Sbjct: 536 E------RQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECEL 589
Query: 318 TEEKAQGKSQIQAPNPKQEPWHGENAKGESGQSTNREQD 356
+E+ + + +I+ P EP K ES S N+E++
Sbjct: 590 EKEREKLEEKIEPREPNLEPM---VEKQESENSCNKEEE 625
>gi|126723564 pecanex-like 1 [Homo sapiens]
Length = 2341
Score = 37.0 bits (84), Expect = 0.032
Identities = 71/347 (20%), Positives = 123/347 (35%), Gaps = 37/347 (10%)
Query: 41 HGQKGQHYSGQKGKQQTESKGSFSIQYTYHVDANDHDQSRKSQQYDLNALHKTTKSQRHL 100
H Q+G S + + F+ Q ++ KS D +A+ +K ++ +
Sbjct: 477 HNQRGLSTSASEEANKNPHANEFTSQGDRPPGNTAENKEEKS---DKSAVSVDSKVRKDV 533
Query: 101 GGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAHRGTQNPSQDQGN---------SPS 151
GG Q+ EG KS HR HK G+ G + S + S
Sbjct: 534 GGKQK------EGDVRPKSSSVIHRTASAHKSGRRRTGKKRASSFDSSRHRDYVCFRGVS 587
Query: 152 G-KGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQTEELVANKQQRET 210
G K S+ + + E+ LS+ + S Q S +S+ Q+ E +T
Sbjct: 588 GTKPHSAIFCHDEDSSDQSDLSRASSVQSAHQFSSDSSSSTTSHSCQSPE--GRYSALKT 645
Query: 211 KNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQDELLVYNKNQHQT 270
K++H+ +G EH+ K + + + S + V + +
Sbjct: 646 KHTHKERG-------TDSEHTHKAHLVPEGTSKKRATRRTSSTNSAKTRARVLSLDSGTV 698
Query: 271 KNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTEEKAQGK----S 326
LN R S + +T + L E V ++S SQ E + + +
Sbjct: 699 ACLNDS---NRLMAPESIKPLTTSKSDLEAKEGEVLDELSLLGRASQLETVTRSRNSLPN 755
Query: 327 QIQAP-NPKQEPWHGENAKGESGQSTNREQDLLSHEQ-KGRHQHGSH 371
Q+ P +Q+ G E S RE+ + + RH GS+
Sbjct: 756 QVAFPEGEEQDAVSGAAQASEEAVSFRRERSTFRRQAVRRRHNAGSN 802
>gi|21361831 partitioning-defective protein 3 homolog [Homo sapiens]
Length = 1356
Score = 36.6 bits (83), Expect = 0.041
Identities = 42/200 (21%), Positives = 77/200 (38%), Gaps = 18/200 (9%)
Query: 189 GSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLC-PAHQDKLQ 247
G SSY + N + + + H Y V + R S V ++ P++ D++Q
Sbjct: 1099 GGVSSY---EGSMALNARPQSPREGHMMDALYAQVKKPRNSKPSPVDSNRSTPSNHDRIQ 1155
Query: 248 HGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTE----ERRLHYGEN 303
++ + + V +++ +T + Q + R A + S S E +R E+
Sbjct: 1156 RLRQEFQQAKQDEDV--EDRRRTYSFEQPWPNARPATQSGRHSVSVEVQMQRQRQEERES 1213
Query: 304 GVQKDVSQSSIYSQTEEKAQGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQK 363
Q SS+ Q+ + A S Q+ W + GE QS S++
Sbjct: 1214 SQQAQRQYSSLPRQSRKNASSVS--------QDSWEQNYSPGEGFQSAKENPRYSSYQGS 1265
Query: 364 GRHQHGSHGGLDIVIIEQED 383
G HG V++E ++
Sbjct: 1266 RNGYLGGHGFNARVMLETQE 1285
>gi|219555661 intraflagellar transport 81-like isoform 1 [Homo
sapiens]
Length = 676
Score = 36.6 bits (83), Expect = 0.041
Identities = 48/209 (22%), Positives = 75/209 (35%), Gaps = 26/209 (12%)
Query: 140 QNPSQDQGNSPSGKGISSQYSNTEERLW-VHGLSKEQTSVSGAQKGRKQGGSQSSYVLQT 198
+N Q KGIS YS T+E L V L E + G + Y L +
Sbjct: 440 ENIQQQLQTMEEKKGISG-YSYTQEELERVSALKSEVDEMKGRTLDDMSEMVKKLYSLVS 498
Query: 199 EELVA------------NKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKL 246
E+ A K Q T+ + K Y + E + SK++ + ++ L
Sbjct: 499 EKKSALASVIKELRQLRQKYQELTQECDEKKSQYDSCAAGLESNRSKLEQEVRRLREECL 558
Query: 247 QHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQ 306
Q S+ Y+ KNL + K +Y SS +E+R E +
Sbjct: 559 QEESR-----------YHYTNCMIKNLEVQLRRATDEMK-AYISSDQQEKRKAIREQYTK 606
Query: 307 KDVSQSSIYSQTEEKAQGKSQIQAPNPKQ 335
Q ++ + EK + + PN KQ
Sbjct: 607 NTAEQENLGKKLREKQKVIRESHGPNMKQ 635
>gi|32526901 intraflagellar transport 81-like isoform 1 [Homo
sapiens]
Length = 676
Score = 36.6 bits (83), Expect = 0.041
Identities = 48/209 (22%), Positives = 75/209 (35%), Gaps = 26/209 (12%)
Query: 140 QNPSQDQGNSPSGKGISSQYSNTEERLW-VHGLSKEQTSVSGAQKGRKQGGSQSSYVLQT 198
+N Q KGIS YS T+E L V L E + G + Y L +
Sbjct: 440 ENIQQQLQTMEEKKGISG-YSYTQEELERVSALKSEVDEMKGRTLDDMSEMVKKLYSLVS 498
Query: 199 EELVA------------NKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKL 246
E+ A K Q T+ + K Y + E + SK++ + ++ L
Sbjct: 499 EKKSALASVIKELRQLRQKYQELTQECDEKKSQYDSCAAGLESNRSKLEQEVRRLREECL 558
Query: 247 QHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQ 306
Q S+ Y+ KNL + K +Y SS +E+R E +
Sbjct: 559 QEESR-----------YHYTNCMIKNLEVQLRRATDEMK-AYISSDQQEKRKAIREQYTK 606
Query: 307 KDVSQSSIYSQTEEKAQGKSQIQAPNPKQ 335
Q ++ + EK + + PN KQ
Sbjct: 607 NTAEQENLGKKLREKQKVIRESHGPNMKQ 635
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.124 0.351
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,200,533
Number of Sequences: 37866
Number of extensions: 781936
Number of successful extensions: 2874
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 176
Number of HSP's that attempted gapping in prelim test: 2574
Number of HSP's gapped (non-prelim): 371
length of query: 402
length of database: 18,247,518
effective HSP length: 105
effective length of query: 297
effective length of database: 14,271,588
effective search space: 4238661636
effective search space used: 4238661636
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.