Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 38045910
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens]
(3333 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens] 6916 0.0
gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens] 6735 0.0
gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens] 3351 0.0
gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens] 3170 0.0
gi|21264602 laminin alpha 5 [Homo sapiens] 1772 0.0
gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 831 0.0
gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 831 0.0
gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens] 830 0.0
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 645 0.0
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 644 0.0
gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 631 e-180
gi|219842266 usherin isoform B [Homo sapiens] 325 5e-88
gi|219842259 usherin isoform A [Homo sapiens] 325 5e-88
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 313 1e-84
gi|110611156 laminin, gamma 3 precursor [Homo sapiens] 295 7e-79
gi|145309326 laminin, gamma 1 precursor [Homo sapiens] 285 7e-76
gi|143770880 laminin, beta 4 [Homo sapiens] 270 1e-71
gi|62868217 laminin, beta 3 precursor [Homo sapiens] 269 3e-71
gi|62868215 laminin, beta 3 precursor [Homo sapiens] 269 3e-71
gi|189083719 laminin, beta 3 precursor [Homo sapiens] 269 3e-71
gi|167614504 laminin, beta 1 precursor [Homo sapiens] 266 3e-70
gi|148613884 netrin 1 [Homo sapiens] 256 3e-67
gi|119703755 laminin, beta 2 precursor [Homo sapiens] 252 4e-66
gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens] 243 2e-63
gi|93204871 netrin 4 [Homo sapiens] 239 3e-62
gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens] 235 5e-61
gi|5453810 netrin 3 [Homo sapiens] 195 6e-49
gi|164414431 netrin G1 isoform 1 [Homo sapiens] 176 3e-43
gi|190014607 netrin G2 [Homo sapiens] 169 6e-41
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 130 2e-29
>gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens]
Length = 3333
Score = 6916 bits (17943), Expect = 0.0
Identities = 3333/3333 (100%), Positives = 3333/3333 (100%)
Query: 1 MAAAARPRGRALGPVLPPTPLLLLVLRVLPACGATARDPGAAAGLSLHPTYFNLAEAARI 60
MAAAARPRGRALGPVLPPTPLLLLVLRVLPACGATARDPGAAAGLSLHPTYFNLAEAARI
Sbjct: 1 MAAAARPRGRALGPVLPPTPLLLLVLRVLPACGATARDPGAAAGLSLHPTYFNLAEAARI 60
Query: 61 WATATCGERGPGEGRPQPELYCKLVGGPTAPGSGHTIQGQFCDYCNSEDPRKAHPVTNAI 120
WATATCGERGPGEGRPQPELYCKLVGGPTAPGSGHTIQGQFCDYCNSEDPRKAHPVTNAI
Sbjct: 61 WATATCGERGPGEGRPQPELYCKLVGGPTAPGSGHTIQGQFCDYCNSEDPRKAHPVTNAI 120
Query: 121 DGSERWWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVDFGST 180
DGSERWWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVDFGST
Sbjct: 121 DGSERWWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVDFGST 180
Query: 181 YSPWQYFAHSKVDCLKEFGREANMAVTRDDDVLCVTEYSRIVPLENGEVVVSLINGRPGA 240
YSPWQYFAHSKVDCLKEFGREANMAVTRDDDVLCVTEYSRIVPLENGEVVVSLINGRPGA
Sbjct: 181 YSPWQYFAHSKVDCLKEFGREANMAVTRDDDVLCVTEYSRIVPLENGEVVVSLINGRPGA 240
Query: 241 KNFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDPTVTRRYYYSIKDISIGGQCV 300
KNFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDPTVTRRYYYSIKDISIGGQCV
Sbjct: 241 KNFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDPTVTRRYYYSIKDISIGGQCV 300
Query: 301 CNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHG 360
CNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHG
Sbjct: 301 CNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHG 360
Query: 361 HASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAP 420
HASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAP
Sbjct: 361 HASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAP 420
Query: 421 DGCIPCSCDPEHADGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSS 480
DGCIPCSCDPEHADGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSS
Sbjct: 421 DGCIPCSCDPEHADGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSS 480
Query: 481 EDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSA 540
EDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSA
Sbjct: 481 EDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSA 540
Query: 541 LGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQ 600
LGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQ
Sbjct: 541 LGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQ 600
Query: 601 CKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGG 660
CKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGG
Sbjct: 601 CKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGG 660
Query: 661 DSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENN 720
DSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENN
Sbjct: 661 DSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENN 720
Query: 721 YYFPDLHHMKYEIEDGSTPNGRDLRFGFDPLAFPEFSWRGYAQMTSVQNDVRITLNVGKS 780
YYFPDLHHMKYEIEDGSTPNGRDLRFGFDPLAFPEFSWRGYAQMTSVQNDVRITLNVGKS
Sbjct: 721 YYFPDLHHMKYEIEDGSTPNGRDLRFGFDPLAFPEFSWRGYAQMTSVQNDVRITLNVGKS 780
Query: 781 SGSLFRVILRYVNPGTEAVSGHITIYPSWGAAQSKEIIFLPSKEPAFVTVPGNGFADPFS 840
SGSLFRVILRYVNPGTEAVSGHITIYPSWGAAQSKEIIFLPSKEPAFVTVPGNGFADPFS
Sbjct: 781 SGSLFRVILRYVNPGTEAVSGHITIYPSWGAAQSKEIIFLPSKEPAFVTVPGNGFADPFS 840
Query: 841 ITPGIWVACIKAEGVLLDYLVLLPRDYYEASVLQLPVTEPCAYAGPPQENCLLYQHLPVT 900
ITPGIWVACIKAEGVLLDYLVLLPRDYYEASVLQLPVTEPCAYAGPPQENCLLYQHLPVT
Sbjct: 841 ITPGIWVACIKAEGVLLDYLVLLPRDYYEASVLQLPVTEPCAYAGPPQENCLLYQHLPVT 900
Query: 901 RFPCTLACEARHFLLDGEPRPVAVRQPTPAHPVMVDLSGREVELHLRLRIPQVGHYVVVV 960
RFPCTLACEARHFLLDGEPRPVAVRQPTPAHPVMVDLSGREVELHLRLRIPQVGHYVVVV
Sbjct: 901 RFPCTLACEARHFLLDGEPRPVAVRQPTPAHPVMVDLSGREVELHLRLRIPQVGHYVVVV 960
Query: 961 EYSTEAAQLFVVDVNVKSSGSVLAGQVNIYSCNYSVLCRSAVIDHMSRIAMYELLADADI 1020
EYSTEAAQLFVVDVNVKSSGSVLAGQVNIYSCNYSVLCRSAVIDHMSRIAMYELLADADI
Sbjct: 961 EYSTEAAQLFVVDVNVKSSGSVLAGQVNIYSCNYSVLCRSAVIDHMSRIAMYELLADADI 1020
Query: 1021 QLKGHMARFLLHQVCIIPIEEFSAEYVRPQVHCIASYGRFVNQSATCVSLAHETPPTALI 1080
QLKGHMARFLLHQVCIIPIEEFSAEYVRPQVHCIASYGRFVNQSATCVSLAHETPPTALI
Sbjct: 1021 QLKGHMARFLLHQVCIIPIEEFSAEYVRPQVHCIASYGRFVNQSATCVSLAHETPPTALI 1080
Query: 1081 LDVLSGRPFPHLPQQSSPSVDVLPGVTLKAPQNQVTLRGRVPHLGRYVFVIHFYQAAHPT 1140
LDVLSGRPFPHLPQQSSPSVDVLPGVTLKAPQNQVTLRGRVPHLGRYVFVIHFYQAAHPT
Sbjct: 1081 LDVLSGRPFPHLPQQSSPSVDVLPGVTLKAPQNQVTLRGRVPHLGRYVFVIHFYQAAHPT 1140
Query: 1141 FPAQVSVDGGWPRAGSFHASFCPHVLGCRDQVIAEGQIEFDISEPEVAATVKVPEGKSLV 1200
FPAQVSVDGGWPRAGSFHASFCPHVLGCRDQVIAEGQIEFDISEPEVAATVKVPEGKSLV
Sbjct: 1141 FPAQVSVDGGWPRAGSFHASFCPHVLGCRDQVIAEGQIEFDISEPEVAATVKVPEGKSLV 1200
Query: 1201 LVRVLVVPAENYDYQILHKKSMDKSLEFITNCGKNSFYLDPQTASRFCKNSARSLVAFYH 1260
LVRVLVVPAENYDYQILHKKSMDKSLEFITNCGKNSFYLDPQTASRFCKNSARSLVAFYH
Sbjct: 1201 LVRVLVVPAENYDYQILHKKSMDKSLEFITNCGKNSFYLDPQTASRFCKNSARSLVAFYH 1260
Query: 1261 KGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCGRRLCE 1320
KGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCGRRLCE
Sbjct: 1261 KGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCGRRLCE 1320
Query: 1321 EMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRC 1380
EMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRC
Sbjct: 1321 EMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRC 1380
Query: 1381 KPRITGRQCDRCASGFYRFPECVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCRE 1440
KPRITGRQCDRCASGFYRFPECVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCRE
Sbjct: 1381 KPRITGRQCDRCASGFYRFPECVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCRE 1440
Query: 1441 GSFHLDPANLKGCTSCFCFGVNNQCHSSHKRRTKFVDMLGWHLETADRVDIPVSFNPGSN 1500
GSFHLDPANLKGCTSCFCFGVNNQCHSSHKRRTKFVDMLGWHLETADRVDIPVSFNPGSN
Sbjct: 1441 GSFHLDPANLKGCTSCFCFGVNNQCHSSHKRRTKFVDMLGWHLETADRVDIPVSFNPGSN 1500
Query: 1501 SMVADLQELPATIHSASWVAPTSYLGDKVSSYGGYLTYQAKSFGLPGDMVLLEKKPDVQL 1560
SMVADLQELPATIHSASWVAPTSYLGDKVSSYGGYLTYQAKSFGLPGDMVLLEKKPDVQL
Sbjct: 1501 SMVADLQELPATIHSASWVAPTSYLGDKVSSYGGYLTYQAKSFGLPGDMVLLEKKPDVQL 1560
Query: 1561 TGQHMSIIYEETNTPRPDRLHHGRVHVVEGNFRHASSRAPVSREELMTVLSRLADVRIQG 1620
TGQHMSIIYEETNTPRPDRLHHGRVHVVEGNFRHASSRAPVSREELMTVLSRLADVRIQG
Sbjct: 1561 TGQHMSIIYEETNTPRPDRLHHGRVHVVEGNFRHASSRAPVSREELMTVLSRLADVRIQG 1620
Query: 1621 LYFTETQRLTLSEVGLEEASDTGSGRIALAVEICACPPAYAGDSCQGCSPGYYRDHKGLY 1680
LYFTETQRLTLSEVGLEEASDTGSGRIALAVEICACPPAYAGDSCQGCSPGYYRDHKGLY
Sbjct: 1621 LYFTETQRLTLSEVGLEEASDTGSGRIALAVEICACPPAYAGDSCQGCSPGYYRDHKGLY 1680
Query: 1681 TGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHTN 1740
TGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHTN
Sbjct: 1681 TGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHTN 1740
Query: 1741 SFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHP 1800
SFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHP
Sbjct: 1741 SFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHP 1800
Query: 1801 LTGDCINQEPKDSSPAEECDDCDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQM 1860
LTGDCINQEPKDSSPAEECDDCDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQM
Sbjct: 1801 LTGDCINQEPKDSSPAEECDDCDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQM 1860
Query: 1861 RHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLN 1920
RHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLN
Sbjct: 1861 RHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLN 1920
Query: 1921 NNVNRATQSAKELDVKIKNVIRNVHILLKQISGTDGEGNNVPSGDFSREWAEAQRMMREL 1980
NNVNRATQSAKELDVKIKNVIRNVHILLKQISGTDGEGNNVPSGDFSREWAEAQRMMREL
Sbjct: 1921 NNVNRATQSAKELDVKIKNVIRNVHILLKQISGTDGEGNNVPSGDFSREWAEAQRMMREL 1980
Query: 1981 RNRNFGKHLREAEADKRESQLLLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRA 2040
RNRNFGKHLREAEADKRESQLLLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRA
Sbjct: 1981 RNRNFGKHLREAEADKRESQLLLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRA 2040
Query: 2041 RLQEAAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQL 2100
RLQEAAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQL
Sbjct: 2041 RLQEAAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQL 2100
Query: 2101 MEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIK 2160
MEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIK
Sbjct: 2101 MEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIK 2160
Query: 2161 RNASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLS 2220
RNASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLS
Sbjct: 2161 RNASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLS 2220
Query: 2221 SNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGD 2280
SNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGD
Sbjct: 2221 SNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGD 2280
Query: 2281 IDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQNEDFKKALTDADNSVN 2340
IDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQNEDFKKALTDADNSVN
Sbjct: 2281 IDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQNEDFKKALTDADNSVN 2340
Query: 2341 KLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQQARDAASKVAVPMRFNGKSGVE 2400
KLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQQARDAASKVAVPMRFNGKSGVE
Sbjct: 2341 KLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQQARDAASKVAVPMRFNGKSGVE 2400
Query: 2401 VRLPNDLEDLKGYTSLSLFLQRPNSRENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTC 2460
VRLPNDLEDLKGYTSLSLFLQRPNSRENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTC
Sbjct: 2401 VRLPNDLEDLKGYTSLSLFLQRPNSRENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTC 2460
Query: 2461 VYNLGDREAELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDM 2520
VYNLGDREAELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDM
Sbjct: 2461 VYNLGDREAELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDM 2520
Query: 2521 DGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKT 2580
DGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKT
Sbjct: 2521 DGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKT 2580
Query: 2581 FNLNTTEVEPCRRRKEESDKNYFEGTGYARVPTQPHAPIPTFGQTIQTTVDRGLLFFAEN 2640
FNLNTTEVEPCRRRKEESDKNYFEGTGYARVPTQPHAPIPTFGQTIQTTVDRGLLFFAEN
Sbjct: 2581 FNLNTTEVEPCRRRKEESDKNYFEGTGYARVPTQPHAPIPTFGQTIQTTVDRGLLFFAEN 2640
Query: 2641 GDRFISLNIEDGKLMVRYKLNSELPKERGVGDAINNGRDHSIQIKIGKLQKRMWINVDVQ 2700
GDRFISLNIEDGKLMVRYKLNSELPKERGVGDAINNGRDHSIQIKIGKLQKRMWINVDVQ
Sbjct: 2641 GDRFISLNIEDGKLMVRYKLNSELPKERGVGDAINNGRDHSIQIKIGKLQKRMWINVDVQ 2700
Query: 2701 NTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNLKKTSGVVRLNDTVGVTKKC 2760
NTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNLKKTSGVVRLNDTVGVTKKC
Sbjct: 2701 NTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNLKKTSGVVRLNDTVGVTKKC 2760
Query: 2761 SEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGILLDHQTWTRNLQVTL 2820
SEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGILLDHQTWTRNLQVTL
Sbjct: 2761 SEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGILLDHQTWTRNLQVTL 2820
Query: 2821 EDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLLRNSKRLKHISS 2880
EDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLLRNSKRLKHISS
Sbjct: 2821 EDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLLRNSKRLKHISS 2880
Query: 2881 SRQSLRLGGSNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLGGCSLNKPPFLMLLKG 2940
SRQSLRLGGSNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLGGCSLNKPPFLMLLKG
Sbjct: 2881 SRQSLRLGGSNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLGGCSLNKPPFLMLLKG 2940
Query: 2941 STRFNKTKTFRINQLLQDTPVASPRSVKVWQDACSPLPKTQANHGALQFGDIPTSHLLFK 3000
STRFNKTKTFRINQLLQDTPVASPRSVKVWQDACSPLPKTQANHGALQFGDIPTSHLLFK
Sbjct: 2941 STRFNKTKTFRINQLLQDTPVASPRSVKVWQDACSPLPKTQANHGALQFGDIPTSHLLFK 3000
Query: 3001 LPQELLKPRSQFAVDMQTTSSRGLVFHTGTKNSFMALYLSKGRLVFALGTDGKKLRIKSK 3060
LPQELLKPRSQFAVDMQTTSSRGLVFHTGTKNSFMALYLSKGRLVFALGTDGKKLRIKSK
Sbjct: 3001 LPQELLKPRSQFAVDMQTTSSRGLVFHTGTKNSFMALYLSKGRLVFALGTDGKKLRIKSK 3060
Query: 3061 EKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRAPVYLGSPPSGKPKSLP 3120
EKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRAPVYLGSPPSGKPKSLP
Sbjct: 3061 EKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRAPVYLGSPPSGKPKSLP 3120
Query: 3121 TNSFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEGGHVVLAHSVLLGPEF 3180
TNSFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEGGHVVLAHSVLLGPEF
Sbjct: 3121 TNSFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEGGHVVLAHSVLLGPEF 3180
Query: 3181 KLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGGTSTSVTPKQSLCDGQ 3240
KLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGGTSTSVTPKQSLCDGQ
Sbjct: 3181 KLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGGTSTSVTPKQSLCDGQ 3240
Query: 3241 WHSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGAPANLTTLRIPVWKSFF 3300
WHSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGAPANLTTLRIPVWKSFF
Sbjct: 3241 WHSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGAPANLTTLRIPVWKSFF 3300
Query: 3301 GCLRNIHVNHIPVPVTEALEVQGPVSLNGCPDQ 3333
GCLRNIHVNHIPVPVTEALEVQGPVSLNGCPDQ
Sbjct: 3301 GCLRNIHVNHIPVPVTEALEVQGPVSLNGCPDQ 3333
>gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens]
Length = 3277
Score = 6735 bits (17473), Expect = 0.0
Identities = 3262/3333 (97%), Positives = 3267/3333 (98%), Gaps = 56/3333 (1%)
Query: 1 MAAAARPRGRALGPVLPPTPLLLLVLRVLPACGATARDPGAAAGLSLHPTYFNLAEAARI 60
MAAAARPRGRALGPVLPPTPLLLLVLRVLPACGATARDPGAAAGLSLHPTYFNLAEAARI
Sbjct: 1 MAAAARPRGRALGPVLPPTPLLLLVLRVLPACGATARDPGAAAGLSLHPTYFNLAEAARI 60
Query: 61 WATATCGERGPGEGRPQPELYCKLVGGPTAPGSGHTIQGQFCDYCNSEDPRKAHPVTNAI 120
WATATCGERGPGEGRPQPELYCKLVGGPTAPGSGHTIQGQFCDYCNSEDPRKAHPVTNAI
Sbjct: 61 WATATCGERGPGEGRPQPELYCKLVGGPTAPGSGHTIQGQFCDYCNSEDPRKAHPVTNAI 120
Query: 121 DGSERWWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVDFGST 180
DGSERWWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVDFGST
Sbjct: 121 DGSERWWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVDFGST 180
Query: 181 YSPWQYFAHSKVDCLKEFGREANMAVTRDDDVLCVTEYSRIVPLENGEVVVSLINGRPGA 240
YSPWQYFAHSKVDCLKEFGREANMAVTRDDDVLCVTEYSRIVPLENGEVVVSLINGRPGA
Sbjct: 181 YSPWQYFAHSKVDCLKEFGREANMAVTRDDDVLCVTEYSRIVPLENGEVVVSLINGRPGA 240
Query: 241 KNFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDPTVTRRYYYSIKDISIGGQCV 300
KNFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDPTVTRRYYYSIKDISIGGQCV
Sbjct: 241 KNFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDPTVTRRYYYSIKDISIGGQCV 300
Query: 301 CNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHG 360
CNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHG
Sbjct: 301 CNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHG 360
Query: 361 HASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAP 420
HASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAP
Sbjct: 361 HASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAP 420
Query: 421 DGCIPCSCDPEHADGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSS 480
DGCIPCSCDPEHADGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSS
Sbjct: 421 DGCIPCSCDPEHADGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSS 480
Query: 481 EDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSA 540
EDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSA
Sbjct: 481 EDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSA 540
Query: 541 LGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQ 600
LGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQ
Sbjct: 541 LGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQ 600
Query: 601 CKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGG 660
CKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGG
Sbjct: 601 CKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGG 660
Query: 661 DSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENN 720
DSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENN
Sbjct: 661 DSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENN 720
Query: 721 YYFPDLHHMKYEIEDGSTPNGRDLRFGFDPLAFPEFSWRGYAQMTSVQNDVRITLNVGKS 780
YYFPDLHHMKYEIEDGSTPNGRDLRFGFDPLAFPEFSWRGYAQMTSVQNDVRITLNVGKS
Sbjct: 721 YYFPDLHHMKYEIEDGSTPNGRDLRFGFDPLAFPEFSWRGYAQMTSVQNDVRITLNVGKS 780
Query: 781 SGSLFRVILRYVNPGTEAVSGHITIYPSWGAAQSKEIIFLPSKEPAFVTVPGNGFADPFS 840
SGSLFRVILRYVNPGTEAVSGHITIYPSWGAAQSKEIIFLPSKEPAFVTVPGNGFADPFS
Sbjct: 781 SGSLFRVILRYVNPGTEAVSGHITIYPSWGAAQSKEIIFLPSKEPAFVTVPGNGFADPFS 840
Query: 841 ITPGIWVACIKAEGVLLDYLVLLPRDYYEASVLQLPVTEPCAYAGPPQENCLLYQHLPVT 900
ITPGIWVACIKAEGVLLDYLVLLPRDYYEASVLQLPVTEPCAYAGPPQENCLLYQHLPVT
Sbjct: 841 ITPGIWVACIKAEGVLLDYLVLLPRDYYEASVLQLPVTEPCAYAGPPQENCLLYQHLPVT 900
Query: 901 RFPCTLACEARHFLLDGEPRPVAVRQPTPAHPVMVDLSGREVELHLRLRIPQVGHYVVVV 960
RFPCTLACEARHFLLDGEPRPVAVRQPTPAHPVMVDLSGREVELHLRLRIPQVGHYVVVV
Sbjct: 901 RFPCTLACEARHFLLDGEPRPVAVRQPTPAHPVMVDLSGREVELHLRLRIPQVGHYVVVV 960
Query: 961 EYSTEAAQLFVVDVNVKSSGSVLAGQVNIYSCNYSVLCRSAVIDHMSRIAMYELLADADI 1020
EYSTEAAQLFVVDVNVKSSGSVLAGQVNIYSCNYSVLCRSAVIDHMSRIAMYELLADADI
Sbjct: 961 EYSTEAAQLFVVDVNVKSSGSVLAGQVNIYSCNYSVLCRSAVIDHMSRIAMYELLADADI 1020
Query: 1021 QLKGHMARFLLHQVCIIPIEEFSAEYVRPQVHCIASYGRFVNQSATCVSLAHETPPTALI 1080
QLKGHMARFLLHQVCIIPIEEFSAEYVRPQVHCIASYGRFVNQSATCVSLAHETPPTALI
Sbjct: 1021 QLKGHMARFLLHQVCIIPIEEFSAEYVRPQVHCIASYGRFVNQSATCVSLAHETPPTALI 1080
Query: 1081 LDVLSGRPFPHLPQQSSPSVDVLPGVTLKAPQNQVTLRGRVPHLGRYVFVIHFYQAAHPT 1140
LDVLSGRPFPHLPQQSSPSVDVLPGVTLKAPQNQVTLRGRVPHLGRYVFVIHFYQAAHPT
Sbjct: 1081 LDVLSGRPFPHLPQQSSPSVDVLPGVTLKAPQNQVTLRGRVPHLGRYVFVIHFYQAAHPT 1140
Query: 1141 FPAQVSVDGGWPRAGSFHASFCPHVLGCRDQVIAEGQIEFDISEPEVAATVKVPEGKSLV 1200
FPAQVSVDGGWPRAGSFHASFCPHVLGCRDQVIAEGQIEFDISEPEVAATVKVPEGKSLV
Sbjct: 1141 FPAQVSVDGGWPRAGSFHASFCPHVLGCRDQVIAEGQIEFDISEPEVAATVKVPEGKSLV 1200
Query: 1201 LVRVLVVPAENYDYQILHKKSMDKSLEFITNCGKNSFYLDPQTASRFCKNSARSLVAFYH 1260
LVRVLVVPAENYDYQILHKKSMDKSLEFITNCGKNSFYLDPQTASRFCKNSARSLVAFYH
Sbjct: 1201 LVRVLVVPAENYDYQILHKKSMDKSLEFITNCGKNSFYLDPQTASRFCKNSARSLVAFYH 1260
Query: 1261 KGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCGRRLCE 1320
KGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCGRRLCE
Sbjct: 1261 KGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCGRRLCE 1320
Query: 1321 EMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRC 1380
EMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRC
Sbjct: 1321 EMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRC 1380
Query: 1381 KPRITGRQCDRCASGFYRFPECVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCRE 1440
KPRITGRQCDRCASGFYRFPECVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCRE
Sbjct: 1381 KPRITGRQCDRCASGFYRFPECVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCRE 1440
Query: 1441 GSFHLDPANLKGCTSCFCFGVNNQCHSSHKRRTKFVDMLGWHLETADRVDIPVSFNPGSN 1500
GSFHLDPANLKGCTSCFCFGVNNQCHSSHKRRTKFVDMLGWHLETADRVDIPVSFNPGSN
Sbjct: 1441 GSFHLDPANLKGCTSCFCFGVNNQCHSSHKRRTKFVDMLGWHLETADRVDIPVSFNPGSN 1500
Query: 1501 SMVADLQELPATIHSASWVAPTSYLGDKVSSYGGYLTYQAKSFGLPGDMVLLEKKPDVQL 1560
SMVADLQELPATIHSASWVAPTSYLGDKVSSYGGYLTYQAKSFGLPGDMVLLEKKPDVQL
Sbjct: 1501 SMVADLQELPATIHSASWVAPTSYLGDKVSSYGGYLTYQAKSFGLPGDMVLLEKKPDVQL 1560
Query: 1561 TGQHMSIIYEETNTPRPDRLHHGRVHVVEGNFRHASSRAPVSREELMTVLSRLADVRIQG 1620
TGQHMSIIYEETNTPRPDRLHHGRVHVVEGNFRHASSRAPVSREELMTVLSRLADVRIQG
Sbjct: 1561 TGQHMSIIYEETNTPRPDRLHHGRVHVVEGNFRHASSRAPVSREELMTVLSRLADVRIQG 1620
Query: 1621 LYFTETQRLTLSEVGLEEASDTGSGRIALAVEICACPPAYAGDSCQGCSPGYYRDHKGLY 1680
LYFTETQRLTLSEVGLEEASDTGSGRIALAVEICACPPAYAGDSCQGCSPGYYRDHKGLY
Sbjct: 1621 LYFTETQRLTLSEVGLEEASDTGSGRIALAVEICACPPAYAGDSCQGCSPGYYRDHKGLY 1680
Query: 1681 TGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHTN 1740
TGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHTN
Sbjct: 1681 TGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHTN 1740
Query: 1741 SFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHP 1800
SFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHP
Sbjct: 1741 SFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHP 1800
Query: 1801 LTGDCINQEPKDSSPAEECDDCDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQM 1860
LTGDCINQEPKDSSPAEECDDCDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQM
Sbjct: 1801 LTGDCINQEPKDSSPAEECDDCDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQM 1860
Query: 1861 RHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLN 1920
RHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLN
Sbjct: 1861 RHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLN 1920
Query: 1921 NNVNRATQSAKELDVKIKNVIRNVHILLKQISGTDGEGNNVPSGDFSREWAEAQRMMREL 1980
NNVNRATQSAKELDVKIKNVIRNVH+L N + R W +
Sbjct: 1921 NNVNRATQSAKELDVKIKNVIRNVHML-----------NRI------RTWQKTH------ 1957
Query: 1981 RNRNFGKHLREAEADKRESQLLLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRA 2040
+ E+ L N IR DSLNEYEAKLSDLRA
Sbjct: 1958 ---------------QGENNGLANSIR------------------DSLNEYEAKLSDLRA 1984
Query: 2041 RLQEAAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQL 2100
RLQEAAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQL
Sbjct: 1985 RLQEAAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQL 2044
Query: 2101 MEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIK 2160
MEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIK
Sbjct: 2045 MEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIK 2104
Query: 2161 RNASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLS 2220
RNASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLS
Sbjct: 2105 RNASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLS 2164
Query: 2221 SNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGD 2280
SNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGD
Sbjct: 2165 SNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGD 2224
Query: 2281 IDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQNEDFKKALTDADNSVN 2340
IDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQNEDFKKALTDADNSVN
Sbjct: 2225 IDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQNEDFKKALTDADNSVN 2284
Query: 2341 KLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQQARDAASKVAVPMRFNGKSGVE 2400
KLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQQARDAASKVAVPMRFNGKSGVE
Sbjct: 2285 KLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQQARDAASKVAVPMRFNGKSGVE 2344
Query: 2401 VRLPNDLEDLKGYTSLSLFLQRPNSRENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTC 2460
VRLPNDLEDLKGYTSLSLFLQRPNSRENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTC
Sbjct: 2345 VRLPNDLEDLKGYTSLSLFLQRPNSRENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTC 2404
Query: 2461 VYNLGDREAELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDM 2520
VYNLGDREAELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDM
Sbjct: 2405 VYNLGDREAELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDM 2464
Query: 2521 DGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKT 2580
DGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKT
Sbjct: 2465 DGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKT 2524
Query: 2581 FNLNTTEVEPCRRRKEESDKNYFEGTGYARVPTQPHAPIPTFGQTIQTTVDRGLLFFAEN 2640
FNLNTTEVEPCRRRKEESDKNYFEGTGYARVPTQPHAPIPTFGQTIQTTVDRGLLFFAEN
Sbjct: 2525 FNLNTTEVEPCRRRKEESDKNYFEGTGYARVPTQPHAPIPTFGQTIQTTVDRGLLFFAEN 2584
Query: 2641 GDRFISLNIEDGKLMVRYKLNSELPKERGVGDAINNGRDHSIQIKIGKLQKRMWINVDVQ 2700
GDRFISLNIEDGKLMVRYKLNSELPKERGVGDAINNGRDHSIQIKIGKLQKRMWINVDVQ
Sbjct: 2585 GDRFISLNIEDGKLMVRYKLNSELPKERGVGDAINNGRDHSIQIKIGKLQKRMWINVDVQ 2644
Query: 2701 NTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNLKKTSGVVRLNDTVGVTKKC 2760
NTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNLKKTSGVVRLNDTVGVTKKC
Sbjct: 2645 NTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNLKKTSGVVRLNDTVGVTKKC 2704
Query: 2761 SEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGILLDHQTWTRNLQVTL 2820
SEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGILLDHQTWTRNLQVTL
Sbjct: 2705 SEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGILLDHQTWTRNLQVTL 2764
Query: 2821 EDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLLRNSKRLKHISS 2880
EDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLLRNSKRLKHISS
Sbjct: 2765 EDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLLRNSKRLKHISS 2824
Query: 2881 SRQSLRLGGSNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLGGCSLNKPPFLMLLKG 2940
SRQSLRLGGSNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLGGCSLNKPPFLMLLKG
Sbjct: 2825 SRQSLRLGGSNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLGGCSLNKPPFLMLLKG 2884
Query: 2941 STRFNKTKTFRINQLLQDTPVASPRSVKVWQDACSPLPKTQANHGALQFGDIPTSHLLFK 3000
STRFNKTKTFRINQLLQDTPVASPRSVKVWQDACSPLPKTQANHGALQFGDIPTSHLLFK
Sbjct: 2885 STRFNKTKTFRINQLLQDTPVASPRSVKVWQDACSPLPKTQANHGALQFGDIPTSHLLFK 2944
Query: 3001 LPQELLKPRSQFAVDMQTTSSRGLVFHTGTKNSFMALYLSKGRLVFALGTDGKKLRIKSK 3060
LPQELLKPRSQFAVDMQTTSSRGLVFHTGTKNSFMALYLSKGRLVFALGTDGKKLRIKSK
Sbjct: 2945 LPQELLKPRSQFAVDMQTTSSRGLVFHTGTKNSFMALYLSKGRLVFALGTDGKKLRIKSK 3004
Query: 3061 EKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRAPVYLGSPPSGKPKSLP 3120
EKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRAPVYLGSPPSGKPKSLP
Sbjct: 3005 EKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRAPVYLGSPPSGKPKSLP 3064
Query: 3121 TNSFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEGGHVVLAHSVLLGPEF 3180
TNSFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEGGHVVLAHSVLLGPEF
Sbjct: 3065 TNSFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEGGHVVLAHSVLLGPEF 3124
Query: 3181 KLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGGTSTSVTPKQSLCDGQ 3240
KLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGGTSTSVTPKQSLCDGQ
Sbjct: 3125 KLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGGTSTSVTPKQSLCDGQ 3184
Query: 3241 WHSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGAPANLTTLRIPVWKSFF 3300
WHSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGAPANLTTLRIPVWKSFF
Sbjct: 3185 WHSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGAPANLTTLRIPVWKSFF 3244
Query: 3301 GCLRNIHVNHIPVPVTEALEVQGPVSLNGCPDQ 3333
GCLRNIHVNHIPVPVTEALEVQGPVSLNGCPDQ
Sbjct: 3245 GCLRNIHVNHIPVPVTEALEVQGPVSLNGCPDQ 3277
>gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens]
Length = 1724
Score = 3351 bits (8688), Expect = 0.0
Identities = 1668/1668 (100%), Positives = 1668/1668 (100%)
Query: 1666 QGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGN 1725
QGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGN
Sbjct: 57 QGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGN 116
Query: 1726 AVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQ 1785
AVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQ
Sbjct: 117 AVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQ 176
Query: 1786 PCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMTLLNDLATMGEQLRLVKS 1845
PCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMTLLNDLATMGEQLRLVKS
Sbjct: 177 PCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMTLLNDLATMGEQLRLVKS 236
Query: 1846 QLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFETL 1905
QLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFETL
Sbjct: 237 QLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFETL 296
Query: 1906 QEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHILLKQISGTDGEGNNVPSGD 1965
QEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHILLKQISGTDGEGNNVPSGD
Sbjct: 297 QEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHILLKQISGTDGEGNNVPSGD 356
Query: 1966 FSREWAEAQRMMRELRNRNFGKHLREAEADKRESQLLLNRIRTWQKTHQGENNGLANSIR 2025
FSREWAEAQRMMRELRNRNFGKHLREAEADKRESQLLLNRIRTWQKTHQGENNGLANSIR
Sbjct: 357 FSREWAEAQRMMRELRNRNFGKHLREAEADKRESQLLLNRIRTWQKTHQGENNGLANSIR 416
Query: 2026 DSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLT 2085
DSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLT
Sbjct: 417 DSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLT 476
Query: 2086 TADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKH 2145
TADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKH
Sbjct: 477 TADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKH 536
Query: 2146 ARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQ 2205
ARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQ
Sbjct: 537 ARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQ 596
Query: 2206 TVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTN 2265
TVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTN
Sbjct: 597 TVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTN 656
Query: 2266 LTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQN 2325
LTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQN
Sbjct: 657 LTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQN 716
Query: 2326 EDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQQARDAAS 2385
EDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQQARDAAS
Sbjct: 717 EDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQQARDAAS 776
Query: 2386 KVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSRENGGTENMFVMYLGNKDAS 2445
KVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSRENGGTENMFVMYLGNKDAS
Sbjct: 777 KVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSRENGGTENMFVMYLGNKDAS 836
Query: 2446 RDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTK 2505
RDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTK
Sbjct: 837 RDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTK 896
Query: 2506 GATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELD 2565
GATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELD
Sbjct: 897 GATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELD 956
Query: 2566 DLNENVLSLYNFKKTFNLNTTEVEPCRRRKEESDKNYFEGTGYARVPTQPHAPIPTFGQT 2625
DLNENVLSLYNFKKTFNLNTTEVEPCRRRKEESDKNYFEGTGYARVPTQPHAPIPTFGQT
Sbjct: 957 DLNENVLSLYNFKKTFNLNTTEVEPCRRRKEESDKNYFEGTGYARVPTQPHAPIPTFGQT 1016
Query: 2626 IQTTVDRGLLFFAENGDRFISLNIEDGKLMVRYKLNSELPKERGVGDAINNGRDHSIQIK 2685
IQTTVDRGLLFFAENGDRFISLNIEDGKLMVRYKLNSELPKERGVGDAINNGRDHSIQIK
Sbjct: 1017 IQTTVDRGLLFFAENGDRFISLNIEDGKLMVRYKLNSELPKERGVGDAINNGRDHSIQIK 1076
Query: 2686 IGKLQKRMWINVDVQNTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNLKKTS 2745
IGKLQKRMWINVDVQNTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNLKKTS
Sbjct: 1077 IGKLQKRMWINVDVQNTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNLKKTS 1136
Query: 2746 GVVRLNDTVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGI 2805
GVVRLNDTVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGI
Sbjct: 1137 GVVRLNDTVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGI 1196
Query: 2806 LLDHQTWTRNLQVTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLID 2865
LLDHQTWTRNLQVTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLID
Sbjct: 1197 LLDHQTWTRNLQVTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLID 1256
Query: 2866 DQLLRNSKRLKHISSSRQSLRLGGSNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLG 2925
DQLLRNSKRLKHISSSRQSLRLGGSNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLG
Sbjct: 1257 DQLLRNSKRLKHISSSRQSLRLGGSNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLG 1316
Query: 2926 GCSLNKPPFLMLLKGSTRFNKTKTFRINQLLQDTPVASPRSVKVWQDACSPLPKTQANHG 2985
GCSLNKPPFLMLLKGSTRFNKTKTFRINQLLQDTPVASPRSVKVWQDACSPLPKTQANHG
Sbjct: 1317 GCSLNKPPFLMLLKGSTRFNKTKTFRINQLLQDTPVASPRSVKVWQDACSPLPKTQANHG 1376
Query: 2986 ALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTGTKNSFMALYLSKGRLV 3045
ALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTGTKNSFMALYLSKGRLV
Sbjct: 1377 ALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTGTKNSFMALYLSKGRLV 1436
Query: 3046 FALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRAP 3105
FALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRAP
Sbjct: 1437 FALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRAP 1496
Query: 3106 VYLGSPPSGKPKSLPTNSFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEG 3165
VYLGSPPSGKPKSLPTNSFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEG
Sbjct: 1497 VYLGSPPSGKPKSLPTNSFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEG 1556
Query: 3166 GHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGG 3225
GHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGG
Sbjct: 1557 GHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGG 1616
Query: 3226 TSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGAP 3285
TSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGAP
Sbjct: 1617 TSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGAP 1676
Query: 3286 ANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCPDQ 3333
ANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCPDQ
Sbjct: 1677 ANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCPDQ 1724
Score = 97.4 bits (241), Expect = 2e-19
Identities = 61/199 (30%), Positives = 77/199 (38%), Gaps = 49/199 (24%)
Query: 333 CCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCIN 392
C GY +R + C CNC+GH++ C G G+C+N
Sbjct: 59 CSPGY----YRDHKGLYTGRCVPCNCNGHSNQCQ------------------DGSGICVN 96
Query: 393 CQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADGCEQGSG--RCHCKPNFH 450
CQHNTAG +CE+C +GY YG V PC A GC G RC CK +
Sbjct: 97 CQHNTAGEHCERCQEGY---YGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYT 153
Query: 451 GDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCL 510
G CE+CA GY+ P G + C CN G L G C+
Sbjct: 154 GTQCERCAPGYFGNP----------------QKFGGSCQPCSCNSNGQLGSCHPLTGDCI 197
Query: 511 ------CRPGVEGPRCDTC 523
P E CD+C
Sbjct: 198 NQEPKDSSPAEECDDCDSC 216
Score = 80.9 bits (198), Expect = 2e-14
Identities = 53/176 (30%), Positives = 78/176 (44%), Gaps = 24/176 (13%)
Query: 1283 GQCPCQPNVIG-RQCTRCATGHYG------FPRCKPCSCG--RRLCEEMTGQC-RCPPRT 1332
GQ Q + + R C+ G+Y RC PC+C C++ +G C C T
Sbjct: 42 GQSQLQASYVEFRPSQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNT 101
Query: 1333 VRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSG--QCRCKPRITGRQCD 1390
CE C+ + C C C + C + G +C CK TG QC+
Sbjct: 102 AGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATG---CVVNGGDVRCSCKAGYTGTQCE 158
Query: 1391 RCASGFYRFPE-----CVPCNCNRDGTEPGVCDPGTGACLCKENVEGT---ECNVC 1438
RCA G++ P+ C PC+CN +G + G C P TG C+ +E + + EC+ C
Sbjct: 159 RCAPGYFGNPQKFGGSCQPCSCNSNG-QLGSCHPLTGDCINQEPKDSSPAEECDDC 213
Score = 71.6 bits (174), Expect = 1e-11
Identities = 55/187 (29%), Positives = 72/187 (38%), Gaps = 36/187 (19%)
Query: 286 YYYSIKDISIGG--QCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWR 343
YY K + G C CNGH+ C + CQH+T GE C+RC GY
Sbjct: 63 YYRDHKGLYTGRCVPCNCNGHSNQCQDGSG---ICVNCQHNTAGEHCERCQEGYYGNAVH 119
Query: 344 PAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCE 403
+ C AC C H + S T + GG V +C+ G CE
Sbjct: 120 GS-------CRACPC-PHTN-------------SFATGCVVNGGDVRCSCKAGYTGTQCE 158
Query: 404 QCAKGYYRPYGVPVDAPDGCIPCSCDPEHADG-CEQGSGRC------HCKPNFHGDNCEK 456
+CA GY +G P C PCSC+ G C +G C P D+C+
Sbjct: 159 RCAPGY---FGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDS 215
Query: 457 CAIGYYN 463
C + N
Sbjct: 216 CVMTLLN 222
Score = 64.3 bits (155), Expect = 2e-09
Identities = 37/114 (32%), Positives = 51/114 (44%), Gaps = 9/114 (7%)
Query: 493 CNLEGVLPEICDAHGRCL-CRPGVEGPRCDTCRSGFYSFPI---CQACWCSALGSYQMPC 548
CN G + D G C+ C+ G C+ C+ G+Y + C+AC C S+ C
Sbjct: 78 CNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGC 137
Query: 549 SSVTG--QCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAG-TINSNLGYC 599
G +C C+ G TG +C+RC G + P G S C P N LG C
Sbjct: 138 VVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGS--CQPCSCNSNGQLGSC 189
Score = 58.9 bits (141), Expect = 8e-08
Identities = 36/126 (28%), Positives = 49/126 (38%), Gaps = 8/126 (6%)
Query: 578 HCQGSSSACDPAGTINSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAG 637
+C G S+ C I N C+ + G C RC+ Y+ C C C
Sbjct: 79 NCNGHSNQCQDGSGICVN-----CQHNTAGEHCERCQEGYYG--NAVHGSCRACPCPHTN 131
Query: 638 TVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCS 697
+ + GD C CK+ G C+ C GYF + CQ C C+ G L S C
Sbjct: 132 SFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGS-CH 190
Query: 698 GPSGVC 703
+G C
Sbjct: 191 PLTGDC 196
Score = 56.2 bits (134), Expect = 5e-07
Identities = 31/97 (31%), Positives = 44/97 (45%), Gaps = 14/97 (14%)
Query: 1260 HKGALPCECHPTGATGPHCSPEGG--QCPCQPNVIGRQCTRCATGHYGFPR-----CKPC 1312
H C C T + C GG +C C+ G QC RCA G++G P+ C+PC
Sbjct: 119 HGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPC 178
Query: 1313 SCGRR----LCEEMTGQC-RCPPRTVRP--QCEVCET 1342
SC C +TG C P+ P +C+ C++
Sbjct: 179 SCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDS 215
Score = 54.7 bits (130), Expect = 2e-06
Identities = 38/124 (30%), Positives = 47/124 (37%), Gaps = 15/124 (12%)
Query: 1353 CEGCNCSRRGTIEAAMPECDRDSGQC-RCKPRITGRQCDRCASGFYR---FPECVPCNCN 1408
C CNC+ +C SG C C+ G C+RC G+Y C C C
Sbjct: 75 CVPCNCNGHSN------QCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCP 128
Query: 1409 RDGTEPGVC--DPGTGACLCKENVEGTECNVCREGSFHLDPANLKG-CTSCFCFGVNNQC 1465
+ C + G C CK GT+C C G F +P G C C C N Q
Sbjct: 129 HTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFG-NPQKFGGSCQPCSC-NSNGQL 186
Query: 1466 HSSH 1469
S H
Sbjct: 187 GSCH 190
Score = 40.8 bits (94), Expect = 0.023
Identities = 21/64 (32%), Positives = 31/64 (48%), Gaps = 5/64 (7%)
Query: 666 CEDGYFALEKSNYFG-CQGCQCDIGGALSSMCSGPSGVC-QCREHVVGKVCQRPENNYYF 723
C GY+ K Y G C C C+ S+ C SG+C C+ + G+ C+R + YY
Sbjct: 59 CSPGYYRDHKGLYTGRCVPCNCN---GHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYG 115
Query: 724 PDLH 727
+H
Sbjct: 116 NAVH 119
>gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens]
Length = 1668
Score = 3170 bits (8218), Expect = 0.0
Identities = 1597/1668 (95%), Positives = 1602/1668 (96%), Gaps = 56/1668 (3%)
Query: 1666 QGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGN 1725
QGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGN
Sbjct: 57 QGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGN 116
Query: 1726 AVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQ 1785
AVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQ
Sbjct: 117 AVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQ 176
Query: 1786 PCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMTLLNDLATMGEQLRLVKS 1845
PCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMTLLNDLATMGEQLRLVKS
Sbjct: 177 PCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMTLLNDLATMGEQLRLVKS 236
Query: 1846 QLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFETL 1905
QLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFETL
Sbjct: 237 QLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFETL 296
Query: 1906 QEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHILLKQISGTDGEGNNVPSGD 1965
QEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVH+L N +
Sbjct: 297 QEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHML-----------NRI---- 341
Query: 1966 FSREWAEAQRMMRELRNRNFGKHLREAEADKRESQLLLNRIRTWQKTHQGENNGLANSIR 2025
R W + + E+ L N IR
Sbjct: 342 --RTWQKTH---------------------QGENNGLANSIR------------------ 360
Query: 2026 DSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLT 2085
DSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLT
Sbjct: 361 DSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLT 420
Query: 2086 TADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKH 2145
TADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKH
Sbjct: 421 TADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKH 480
Query: 2146 ARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQ 2205
ARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQ
Sbjct: 481 ARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQ 540
Query: 2206 TVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTN 2265
TVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTN
Sbjct: 541 TVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTN 600
Query: 2266 LTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQN 2325
LTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQN
Sbjct: 601 LTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQN 660
Query: 2326 EDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQQARDAAS 2385
EDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQQARDAAS
Sbjct: 661 EDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQQARDAAS 720
Query: 2386 KVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSRENGGTENMFVMYLGNKDAS 2445
KVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSRENGGTENMFVMYLGNKDAS
Sbjct: 721 KVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSRENGGTENMFVMYLGNKDAS 780
Query: 2446 RDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTK 2505
RDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTK
Sbjct: 781 RDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTK 840
Query: 2506 GATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELD 2565
GATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELD
Sbjct: 841 GATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELD 900
Query: 2566 DLNENVLSLYNFKKTFNLNTTEVEPCRRRKEESDKNYFEGTGYARVPTQPHAPIPTFGQT 2625
DLNENVLSLYNFKKTFNLNTTEVEPCRRRKEESDKNYFEGTGYARVPTQPHAPIPTFGQT
Sbjct: 901 DLNENVLSLYNFKKTFNLNTTEVEPCRRRKEESDKNYFEGTGYARVPTQPHAPIPTFGQT 960
Query: 2626 IQTTVDRGLLFFAENGDRFISLNIEDGKLMVRYKLNSELPKERGVGDAINNGRDHSIQIK 2685
IQTTVDRGLLFFAENGDRFISLNIEDGKLMVRYKLNSELPKERGVGDAINNGRDHSIQIK
Sbjct: 961 IQTTVDRGLLFFAENGDRFISLNIEDGKLMVRYKLNSELPKERGVGDAINNGRDHSIQIK 1020
Query: 2686 IGKLQKRMWINVDVQNTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNLKKTS 2745
IGKLQKRMWINVDVQNTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNLKKTS
Sbjct: 1021 IGKLQKRMWINVDVQNTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNLKKTS 1080
Query: 2746 GVVRLNDTVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGI 2805
GVVRLNDTVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGI
Sbjct: 1081 GVVRLNDTVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGI 1140
Query: 2806 LLDHQTWTRNLQVTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLID 2865
LLDHQTWTRNLQVTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLID
Sbjct: 1141 LLDHQTWTRNLQVTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLID 1200
Query: 2866 DQLLRNSKRLKHISSSRQSLRLGGSNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLG 2925
DQLLRNSKRLKHISSSRQSLRLGGSNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLG
Sbjct: 1201 DQLLRNSKRLKHISSSRQSLRLGGSNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLG 1260
Query: 2926 GCSLNKPPFLMLLKGSTRFNKTKTFRINQLLQDTPVASPRSVKVWQDACSPLPKTQANHG 2985
GCSLNKPPFLMLLKGSTRFNKTKTFRINQLLQDTPVASPRSVKVWQDACSPLPKTQANHG
Sbjct: 1261 GCSLNKPPFLMLLKGSTRFNKTKTFRINQLLQDTPVASPRSVKVWQDACSPLPKTQANHG 1320
Query: 2986 ALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTGTKNSFMALYLSKGRLV 3045
ALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTGTKNSFMALYLSKGRLV
Sbjct: 1321 ALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTGTKNSFMALYLSKGRLV 1380
Query: 3046 FALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRAP 3105
FALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRAP
Sbjct: 1381 FALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRAP 1440
Query: 3106 VYLGSPPSGKPKSLPTNSFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEG 3165
VYLGSPPSGKPKSLPTNSFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEG
Sbjct: 1441 VYLGSPPSGKPKSLPTNSFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEG 1500
Query: 3166 GHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGG 3225
GHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGG
Sbjct: 1501 GHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGG 1560
Query: 3226 TSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGAP 3285
TSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGAP
Sbjct: 1561 TSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGAP 1620
Query: 3286 ANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCPDQ 3333
ANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCPDQ
Sbjct: 1621 ANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCPDQ 1668
Score = 97.4 bits (241), Expect = 2e-19
Identities = 61/199 (30%), Positives = 77/199 (38%), Gaps = 49/199 (24%)
Query: 333 CCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCIN 392
C GY +R + C CNC+GH++ C G G+C+N
Sbjct: 59 CSPGY----YRDHKGLYTGRCVPCNCNGHSNQCQ------------------DGSGICVN 96
Query: 393 CQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADGCEQGSG--RCHCKPNFH 450
CQHNTAG +CE+C +GY YG V PC A GC G RC CK +
Sbjct: 97 CQHNTAGEHCERCQEGY---YGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYT 153
Query: 451 GDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCL 510
G CE+CA GY+ P G + C CN G L G C+
Sbjct: 154 GTQCERCAPGYFGNP----------------QKFGGSCQPCSCNSNGQLGSCHPLTGDCI 197
Query: 511 ------CRPGVEGPRCDTC 523
P E CD+C
Sbjct: 198 NQEPKDSSPAEECDDCDSC 216
Score = 80.9 bits (198), Expect = 2e-14
Identities = 53/176 (30%), Positives = 78/176 (44%), Gaps = 24/176 (13%)
Query: 1283 GQCPCQPNVIG-RQCTRCATGHYG------FPRCKPCSCG--RRLCEEMTGQC-RCPPRT 1332
GQ Q + + R C+ G+Y RC PC+C C++ +G C C T
Sbjct: 42 GQSQLQASYVEFRPSQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNT 101
Query: 1333 VRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSG--QCRCKPRITGRQCD 1390
CE C+ + C C C + C + G +C CK TG QC+
Sbjct: 102 AGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATG---CVVNGGDVRCSCKAGYTGTQCE 158
Query: 1391 RCASGFYRFPE-----CVPCNCNRDGTEPGVCDPGTGACLCKENVEGT---ECNVC 1438
RCA G++ P+ C PC+CN +G + G C P TG C+ +E + + EC+ C
Sbjct: 159 RCAPGYFGNPQKFGGSCQPCSCNSNG-QLGSCHPLTGDCINQEPKDSSPAEECDDC 213
Score = 71.6 bits (174), Expect = 1e-11
Identities = 55/187 (29%), Positives = 72/187 (38%), Gaps = 36/187 (19%)
Query: 286 YYYSIKDISIGG--QCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWR 343
YY K + G C CNGH+ C + CQH+T GE C+RC GY
Sbjct: 63 YYRDHKGLYTGRCVPCNCNGHSNQCQDGSG---ICVNCQHNTAGEHCERCQEGYYGNAVH 119
Query: 344 PAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCE 403
+ C AC C H + S T + GG V +C+ G CE
Sbjct: 120 GS-------CRACPC-PHTN-------------SFATGCVVNGGDVRCSCKAGYTGTQCE 158
Query: 404 QCAKGYYRPYGVPVDAPDGCIPCSCDPEHADG-CEQGSGRC------HCKPNFHGDNCEK 456
+CA GY +G P C PCSC+ G C +G C P D+C+
Sbjct: 159 RCAPGY---FGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDS 215
Query: 457 CAIGYYN 463
C + N
Sbjct: 216 CVMTLLN 222
Score = 71.6 bits (174), Expect = 1e-11
Identities = 126/665 (18%), Positives = 256/665 (38%), Gaps = 104/665 (15%)
Query: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNC--NGHSNQCQDGSGICVNCQHNTA 1711
C+C Y G C+ C+PGY+ + + + G C PC+C NG C +G C+N Q
Sbjct: 146 CSCKAGYTGTQCERCAPGYFGNPQ-KFGGSCQPCSCNSNGQLGSCHPLTGDCIN-QEPKD 203
Query: 1712 GEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAP 1771
E C + C +C N AT G Q
Sbjct: 204 SSPAEECDD----------CDSCVMTLLNDLAT-----------------MGEQLRLVKS 236
Query: 1772 GYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMTLLN 1831
G G Q + + L +N S+ + + + + L
Sbjct: 237 QLQGLSASAGLLEQMRHMETQAK-----DLRNQLLNYRSAISNHGSKIEGLERELTDLNQ 291
Query: 1832 DLATMGEQLRLVKSQLQGLSASAGLLEQ-MRHMETQAKD-LRN--QLLNYRSAISNHGSK 1887
+ T+ E+ ++ + Q L+ + Q + ++ + K+ +RN L R+ H +
Sbjct: 292 EFETLQEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHMLNRIRTWQKTHQGE 351
Query: 1888 IEGLERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHIL 1947
GL + D E+E K L + A A
Sbjct: 352 NNGLANSIRDSLNEYEA----------KLSDLRARLQEAAAQA----------------- 384
Query: 1948 LKQISGTDGEGNNVPSGDFSREWAEAQRMMRELRN--RNFGKHLREAEADKRESQLLLNR 2005
KQ +G + E R QR ++E+ + +F K+L A++ ++ + L
Sbjct: 385 -KQANGLNQEN--------ERALGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQL 435
Query: 2006 IRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGA 2065
+ QK ++ + SLNE +LSD L +A + +++ R+L
Sbjct: 436 MEKSQKEYE--------KLAASLNEARQELSDKVRELSRSAGKTSLVEEA-EKHARSLQE 486
Query: 2066 IQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEA------R 2119
+ +Q++EI S D++ NI + K+ ++ AAS +E+ +
Sbjct: 487 LAKQLEEIKRNASGDELVRCAVDAATAYENILNAI--KAAEDAANRAASASESALQTVIK 544
Query: 2120 QELSDKVRELSRSAGKTSLVEEAEKHARSL-QELAKQLEEIKRNASGDELVRCAVDA-AT 2177
++L K + LS ++ K L+ EA+ + L QE++ L +++ + + + +D T
Sbjct: 545 EDLPRKAKTLSSNSDK--LLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTNLT 602
Query: 2178 AYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKL 2237
+ L+ I+ + A +++ S I +++ + ++ +++ + TQ
Sbjct: 603 TLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQ--- 659
Query: 2238 KQEVSPALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKAND 2297
++ AL + ++N +T + + + ++ L + G+I + + ++++A D
Sbjct: 660 NEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQL--LPLGNISDNMDRIRELIQQARD 717
Query: 2298 ITDEV 2302
+V
Sbjct: 718 AASKV 722
Score = 64.3 bits (155), Expect = 2e-09
Identities = 37/114 (32%), Positives = 51/114 (44%), Gaps = 9/114 (7%)
Query: 493 CNLEGVLPEICDAHGRCL-CRPGVEGPRCDTCRSGFYSFPI---CQACWCSALGSYQMPC 548
CN G + D G C+ C+ G C+ C+ G+Y + C+AC C S+ C
Sbjct: 78 CNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGC 137
Query: 549 SSVTG--QCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAG-TINSNLGYC 599
G +C C+ G TG +C+RC G + P G S C P N LG C
Sbjct: 138 VVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGS--CQPCSCNSNGQLGSC 189
Score = 58.9 bits (141), Expect = 8e-08
Identities = 36/126 (28%), Positives = 49/126 (38%), Gaps = 8/126 (6%)
Query: 578 HCQGSSSACDPAGTINSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAG 637
+C G S+ C I N C+ + G C RC+ Y+ C C C
Sbjct: 79 NCNGHSNQCQDGSGICVN-----CQHNTAGEHCERCQEGYYG--NAVHGSCRACPCPHTN 131
Query: 638 TVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCS 697
+ + GD C CK+ G C+ C GYF + CQ C C+ G L S C
Sbjct: 132 SFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGS-CH 190
Query: 698 GPSGVC 703
+G C
Sbjct: 191 PLTGDC 196
Score = 56.2 bits (134), Expect = 5e-07
Identities = 31/97 (31%), Positives = 44/97 (45%), Gaps = 14/97 (14%)
Query: 1260 HKGALPCECHPTGATGPHCSPEGG--QCPCQPNVIGRQCTRCATGHYGFPR-----CKPC 1312
H C C T + C GG +C C+ G QC RCA G++G P+ C+PC
Sbjct: 119 HGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPC 178
Query: 1313 SCGRR----LCEEMTGQC-RCPPRTVRP--QCEVCET 1342
SC C +TG C P+ P +C+ C++
Sbjct: 179 SCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDS 215
Score = 54.7 bits (130), Expect = 2e-06
Identities = 38/124 (30%), Positives = 47/124 (37%), Gaps = 15/124 (12%)
Query: 1353 CEGCNCSRRGTIEAAMPECDRDSGQC-RCKPRITGRQCDRCASGFYR---FPECVPCNCN 1408
C CNC+ +C SG C C+ G C+RC G+Y C C C
Sbjct: 75 CVPCNCNGHSN------QCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCP 128
Query: 1409 RDGTEPGVC--DPGTGACLCKENVEGTECNVCREGSFHLDPANLKG-CTSCFCFGVNNQC 1465
+ C + G C CK GT+C C G F +P G C C C N Q
Sbjct: 129 HTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFG-NPQKFGGSCQPCSC-NSNGQL 186
Query: 1466 HSSH 1469
S H
Sbjct: 187 GSCH 190
Score = 40.8 bits (94), Expect = 0.023
Identities = 21/64 (32%), Positives = 31/64 (48%), Gaps = 5/64 (7%)
Query: 666 CEDGYFALEKSNYFG-CQGCQCDIGGALSSMCSGPSGVC-QCREHVVGKVCQRPENNYYF 723
C GY+ K Y G C C C+ S+ C SG+C C+ + G+ C+R + YY
Sbjct: 59 CSPGYYRDHKGLYTGRCVPCNCN---GHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYG 115
Query: 724 PDLH 727
+H
Sbjct: 116 NAVH 119
>gi|21264602 laminin alpha 5 [Homo sapiens]
Length = 3695
Score = 1772 bits (4590), Expect = 0.0
Identities = 898/1992 (45%), Positives = 1156/1992 (58%), Gaps = 223/1992 (11%)
Query: 18 PTPLLLLVLRVLPACGATARDPGAAAGLSLHPTYFNLAEAARIWATATCGERGPGEGRPQ 77
P PLLL+ L +L A A AR+ A G SLHP YFNLAE ARI A+ATCGE P G P+
Sbjct: 19 PAPLLLVGLALLGA--ARAREE-AGGGFSLHPPYFNLAEGARIAASATCGEEAPARGSPR 75
Query: 78 P--ELYCKLVGGPTAPGS-GHTIQGQFCDYCNSEDPRKAHPVTNAIDGSERWWQSPPLSS 134
P +LYCKLVGGP A G TI+GQ+CD C + + KAHP +NAIDG+ERWWQSPPLS
Sbjct: 76 PTEDLYCKLVGGPVAGGDPNQTIRGQYCDICTAANSNKAHPASNAIDGTERWWQSPPLSR 135
Query: 135 GTQYNRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVDFGSTYSPWQYFAHSKVDC 194
G +YN VN+TLDLGQ+FHVAY+LIKFANSPRPDLWVLERS+DFG TY PWQ+FA SK DC
Sbjct: 136 GLEYNEVNVTLDLGQVFHVAYVLIKFANSPRPDLWVLERSMDFGRTYQPWQFFASSKRDC 195
Query: 195 LKEFGREANMAVTRDDDVLCVTEYSRIVPLENGEVVVSLINGRPGAKNFTFSHTLREFTK 254
L+ FG + +TRDD +C TEYSRIVPLENGE+VVSL+NGRPGA NF++S LREFTK
Sbjct: 196 LERFGPQTLERITRDDAAICTTEYSRIVPLENGEIVVSLVNGRPGAMNFSYSPLLREFTK 255
Query: 255 ATNIRLRFLRTNTLLGHLISKAQR---------------------------------DPT 281
ATN+RLRFLRTNTLLGHL+ KA R DPT
Sbjct: 256 ATNVRLRFLRTNTLLGHLMGKALRDPTVTRRYYYSIKDISIGGRCVCHGHADACDAKDPT 315
Query: 282 VTRRYYYSIKDISIGG--------------------------QCVCNGHAEVCNINNPEK 315
R + + + GG C C GHA C +
Sbjct: 316 DPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVD 375
Query: 316 LFRC---------------ECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHG 360
R +CQHHT G C+RC G+ + P + H C CNC
Sbjct: 376 RRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPL--DSPHVCRRCNCES 433
Query: 361 HASN---------CYYDPDVERQQASLNTQG---------------------IYAG---- 386
++ CY P+ ++ + +G + AG
Sbjct: 434 DFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVN 493
Query: 387 ---------GGVCIN--------CQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCD 429
G C C+ N G +CE CA G+Y P GC PC C
Sbjct: 494 CDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFYGP---------GCQPCQCS 544
Query: 430 PEHA--DGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAG- 486
D C+ +G+C C+ F G C++CA GY++FP C P T AG
Sbjct: 545 SPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPLCQLCGCSPAGTLPEGCDEAGR 604
Query: 487 -----------------------DIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTC 523
+ + C C+ G L ++C A G C CRPG G C C
Sbjct: 605 CLCQPEFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTACQEC 664
Query: 524 RSGFYSFPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSS 583
GF+ FP C C CSA GS C +GQC CRP VTG RCD C+ GAY+FP+C+ S
Sbjct: 665 SPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNFPYCEAGS 724
Query: 584 SACDPAGTINSNLGY------CQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAG 637
C PAG + C C+ HVEGP+C RCK +W L NP GC+ C C G
Sbjct: 725 --CHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSCDLRG 782
Query: 638 TVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCS 697
T+ G EC+ G G C CK HV G +C +C+DG+F L++++YFGC+ C+CDIGGAL C
Sbjct: 783 TLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCRSCRCDIGGALGQSCE 842
Query: 698 GPSGVCQCREHVVGKVCQRPENNYYFPDLHHMKYEIEDGSTPNGRDLRFGFDPLAFPEFS 757
+GVC+CR + G C P ++Y PDLHH++ E+E+ +TP G +RFGF+PL F FS
Sbjct: 843 PRTGVCRCRPNTQGPTCSEPARDHYLPDLHHLRLELEEAATPEGHAVRFGFNPLEFENFS 902
Query: 758 WRGYAQMTSVQNDVRITLNVGKSSGSLFRVILRYVNPGTEAVSGHITIYPSWGAA----- 812
WRGYAQM VQ + LN+ +S LF ++ RYVN G +VSG +++ +A
Sbjct: 903 WRGYAQMAPVQPRIVARLNL--TSPDLFWLVFRYVNRGAMSVSGRVSVREEGRSATCANC 960
Query: 813 --QSKEIIFLPSKEPAFVTVPGNGFADPFSITPGIWVACIKAEGVLLDYLVLLPRDYYEA 870
QS+ + F PS EPAF+TVP GF +PF + PG W ++AEGVLLDY+VLLP YYEA
Sbjct: 961 TAQSQPVAFPPSTEPAFITVPQRGFGEPFVLNPGTWALRVEAEGVLLDYVVLLPSAYYEA 1020
Query: 871 SVLQLPVTEPCAYAGPPQE---NCLLYQHLPVTRFPCTLACEARHFLLDGEPRPVAVRQP 927
++LQL VTE C Y Q+ NCLLY HLP+ FP EA + PRP Q
Sbjct: 1021 ALLQLRVTEACTYRPSAQQSGDNCLLYTHLPLDGFPSAAGLEALCRQDNSLPRPCPTEQL 1080
Query: 928 TPAHPVMVDLSGREVELHLRLRIPQVGHYVVVVEYSTEAAQLFVVDVNVKSSGSVLAGQV 987
+P+HP ++ +G +V++ L++ +PQ G Y +VVEY+ E A+ V + G +
Sbjct: 1081 SPSHPPLITCTGSDVDVQLQVAVPQPGRYALVVEYANEDARQEVGVAVHTPQRAPQQGLL 1140
Query: 988 NIYSCNYSVLCRSAVIDHMSRIAMYELLADADIQLKGHMARFLLHQVCIIPIEEFSAEYV 1047
+++ C YS LCR D +A++ L ++A ++L ARF LH V ++PIEEFS E+V
Sbjct: 1141 SLHPCLYSTLCRGTARDTQDHLAVFHLDSEASVRLTAEQARFFLHGVTLVPIEEFSPEFV 1200
Query: 1048 RPQVHCIASYGRFVNQSATCVSLAHETPPTALIL------DVLSGRPFPHL--------- 1092
P+V CI+S+G F SA C+ PP +IL + G P H
Sbjct: 1201 EPRVSCISSHGAFGPNSAACLPSRFPKPPQPIILRDCQVIPLPPGLPLTHAQDLTPAMSP 1260
Query: 1093 --PQQSSPSV---DVLPGVTLKAPQNQVTLRGRVPHLGRYVFVIHFYQAAHPTFPAQVSV 1147
P+ P+ D P + L+ PQ V VP LGRY F++H YQ AHPTFP +V +
Sbjct: 1261 AGPRPRPPTAVDPDAEPTL-LREPQATVVFTTHVPTLGRYAFLLHGYQPAHPTFPVEVLI 1319
Query: 1148 DGGWPRAGSFHASFCPHVLGCRDQVIAEGQIEFDISEPEVAATVKVPEGKSLVLVRVLVV 1207
+ G G +ASFCPH GCR V+ EGQ D++ E+ TV+VP+G+ L L VLVV
Sbjct: 1320 NAGRVWQGHANASFCPHGYGCRTLVVCEGQALLDVTHSELTVTVRVPKGRWLWLDYVLVV 1379
Query: 1208 PAENYDYQILHKKSMDKSLEFITNCGKNSFYLDPQTASRFCKNSARSLVAFYHKGALPCE 1267
P Y + L ++ +DKS +FI++C +++ P ++S FC+N+A SL FY+ GA PC
Sbjct: 1380 PENVYSFGYLREEPLDKSYDFISHCAAQGYHISPSSSSLFCRNAAASLSLFYNNGARPCG 1439
Query: 1268 CHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCGRRLCEEMTGQCR 1327
CH GATGP C P GGQCPC +VIGR C+RCATG++GFP C+PC CG RLC+E+TGQC
Sbjct: 1440 CHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFPNCRPCDCGARLCDELTGQCI 1499
Query: 1328 CPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGR 1387
CPPRT+ P C +C+ +F HP+ GCE CNCS G E P CD DSGQC+C+P +TGR
Sbjct: 1500 CPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGR 1559
Query: 1388 QCDRCASGFYRFPECVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCREGSFHLDP 1447
+CD C+ GF+ +P C PC+C+ GT PGVCDP TG C CKENV+G +C+ C G+F LD
Sbjct: 1560 RCDTCSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQCSLGTFSLDA 1619
Query: 1448 ANLKGCTSCFCFGVNNQCHSSHKRRTKFVDMLGWHLETADRVDIPVSFNPGSNSMVADLQ 1507
AN KGCT CFCFG +C SS R +FVDM GW L + DR +P PG+ + ADL+
Sbjct: 1620 ANPKGCTRCFCFGATERCRSSSYTRQEFVDMEGWVLLSTDRQVVPHERQPGTEMLRADLR 1679
Query: 1508 ELPATIHSA----SWVAPTSYLGDKVSSYGGYLTYQAKSFGLPGDM-VLLEKKPDVQLTG 1562
+P + A W AP SYLGD+VSSYGG L Y+ S GD+ V +E +PDV L G
Sbjct: 1680 HVPEAVPEAFPELYWQAPPSYLGDRVSSYGGTLRYELHSETQRGDVFVPMESRPDVVLQG 1739
Query: 1563 QHMSIIYEETNTPRPDRLHHGRVHVVEGNFRHASSRAPVSREELMTVLSRLADVRIQGLY 1622
MSI + E P P +H G++ +VEGNFRH +R VSREELM VL+ L ++I+ L+
Sbjct: 1740 NQMSITFLEPAYPTPGHVHRGQLQLVEGNFRHTETRNTVSREELMMVLASLEQLQIRALF 1799
Query: 1623 FTETQRLTLSEVGLEEASDTGSGRIALAVEICACPPAYAGDSCQGCSPGYYRDHKGLYTG 1682
+ + L V LE AS G G +A VE+C CP +Y GDSCQ C+PG+YRD KGL+ G
Sbjct: 1800 SQISSAVFLRRVALEVASPAGQGALASNVELCLCPASYRGDSCQECAPGFYRDVKGLFLG 1859
Query: 1683 RCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGS--CRACPCP--- 1737
RCVPC C+GHS++C GSG+CV+CQHNT G HCERCQ G+ + S C +CPCP
Sbjct: 1860 RCVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCERCQAGFVSSRDDPSAPCVSCPCPLSV 1919
Query: 1738 HTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQ--- 1794
+N+FA GCV+ GG +C CK GY G CERCAPG+FGNP G SCQPC C+ NG
Sbjct: 1920 PSNNFAEGCVLRGGRTQCLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNL 1979
Query: 1795 -LGSCHPLTGDC 1805
C PLTG C
Sbjct: 1980 LFSDCDPLTGAC 1991
Score = 766 bits (1979), Expect = 0.0
Identities = 566/1793 (31%), Positives = 865/1793 (48%), Gaps = 151/1793 (8%)
Query: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSN------QCQDGSGICVNCQ 1707
C C P YAG SC+ C+PG++ + L + C PC+C+G+ + C +G C C
Sbjct: 1937 CLCKPGYAGASCERCAPGFFGNPLVLGSS-CQPCDCSGNGDPNLLFSDCDPLTGACRGCL 1995
Query: 1708 HNTAGEHCERCQEGYYGNAV-HGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQC 1766
+T G CE C G+YGNA+ G+C C C + A C + G C CKAG TG +C
Sbjct: 1996 RHTTGPRCEICAPGFYGNALLPGNCTRCDCTPCGTEA--CDPHSG--HCLCKAGVTGRRC 2051
Query: 1767 ERCAPGYFGNPQKFGGSCQPCSCNS-------NGQLGSCH-------------------- 1799
+RC G+FG G C+PC+C + Q G CH
Sbjct: 2052 DRCQEGHFGFDGC--GGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGL 2109
Query: 1800 ----------------PLTGDCI----------------NQEPKDSSPAEE---CDDCDS 1824
P TG C +Q P P C+ CD
Sbjct: 2110 PEQGCRRCQCPGGRCDPHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVGHSIHCEVCDH 2169
Query: 1825 CVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNH 1884
CV+ LL+DL G L + QL+G++AS+ ++ + DL++QL +
Sbjct: 2170 CVVLLLDDLERAGALLPAIHEQLRGINASSMAWARLHRLNASIADLQSQLRSPLGPRHET 2229
Query: 1885 GSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNV 1944
++E LE++ T L Q+ L +A +A L AK L I+ V R +
Sbjct: 2230 AQQLEVLEQQSTSLGQDARRLGGQAVGTRDQASQLLAGTEATLGHAKTLLAAIRAVDRTL 2289
Query: 1945 HILLKQISGTDGEGNNVPSGD-FSREWAEAQRMMRELRNRNFGKHLREAEADKRESQLLL 2003
L+ Q + PSG+ R AE +R++ E+R R+ G AEA+ +Q LL
Sbjct: 2290 SELMSQTGHLGLANASAPSGEQLLRTLAEVERLLWEMRARDLGAPQAAAEAELAAAQRLL 2349
Query: 2004 NRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERAL 2063
R++ + EN LA RD L ++EA L DLR L A ++A LN N+ L
Sbjct: 2350 ARVQEQLSSLWEENQALATQTRDRLAQHEAGLMDLREALNRAVDATREAQELNSRNQERL 2409
Query: 2064 GAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELS 2123
++ +E++ + L A +L L ++++++E E+LAASL+ AR L
Sbjct: 2410 EEALQRKQELSRDNATLQATLHAARDTLASVFRLLHSLDQAKEELERLAASLDGARTPLL 2469
Query: 2124 DKVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENIL 2183
+++ S + K LVE AE HA+ L +LA L I + + D L + A++A+ AY IL
Sbjct: 2470 QRMQTFSPAGSKLRLVEAAEAHAQQLGQLALNLSSIILDVNQDRLTQRAIEASNAYSRIL 2529
Query: 2184 NAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSP 2243
A++AAEDAA +A ++ TV+++ L +A+ L +NS L EA + +++ V
Sbjct: 2530 QAVQAAEDAAGQALQQADHTWATVVRQGLVDRAQQLLANS-TALEEAMLQEQQRLGLVWA 2588
Query: 2244 ALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVL 2303
AL + L V +K+ ++ ++ + + + + I+ AK++ +A D V
Sbjct: 2589 ALQGARTQLRDVRAKKDQLEAHIQAAQ-AMLAMDTDETSKKIAHAKAVAAEAQDTATRVQ 2647
Query: 2304 DGLNPIQTDVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPL 2363
L +Q +VER + Y + +D +A+ DA +SV+ L LP L K+ + + +
Sbjct: 2648 SQLQAMQENVERWQGQYEGLRGQDLGQAVLDAGHSVSTLEKTLPQLLAKLSILENRGVHN 2707
Query: 2364 GN--ISDNMDRIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQ 2421
+ +S ++ R+RELI QAR AASKV VPM+FNG+SGV++R P DL DL YT+L +LQ
Sbjct: 2708 ASLALSASIGRVRELIAQARGAASKVKVPMKFNGRSGVQLRTPRDLADLAAYTALKFYLQ 2767
Query: 2422 RPNSRENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTCVYNLGDR-EAELQVDQILTKS 2480
P GTE+ FVMY+G++ A+ DY+G+++ D ++ VY LG+ A L +D+ + +
Sbjct: 2768 GPEPEPGQGTEDRFVMYMGSRQATGDYMGVSLRDKKVHWVYQLGEAGPAVLSIDEDIGEQ 2827
Query: 2481 ETKEAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYV 2540
V R QF ++ T + ET G D + LLNL P++ VFYV
Sbjct: 2828 ------FAAVSLDRTLQFGHMSVTVERQMIQ-ETKG--DTVAPGAEGLLNLRPDDFVFYV 2878
Query: 2541 GGYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPCRRRKEE--- 2597
GGYP F P L FP Y+GCIE+D LNE V+SLYNF++TF L+T PC R K
Sbjct: 2879 GGYPSTFTPPPLLRFPGYRGCIEMDTLNEEVVSLYNFERTFQLDTAVDRPCARSKSTGDP 2938
Query: 2598 --SDKNYFEGTGYARVPTQPH-APIPTFGQTIQTTVDRGLLFFAENGDRFISLNIEDGKL 2654
+D +Y +GTG+AR+ + F Q ++ G+LFF + +F+ L +++G L
Sbjct: 2939 WLTDGSYLDGTGFARISFDSQISTTKRFEQELRLVSYSGVLFFLKQQSQFLCLAVQEGSL 2998
Query: 2655 MVRYKLNSELPKERGVGDAIN-NGRDHSIQI-KIGKLQKRMWINVD---VQNTIIDGEVF 2709
++ Y + L K + +IQ+ +G +KR+ + V+ V + D ++
Sbjct: 2999 VLLYDFGAGLKKAVPLQPPPPLTSASKAIQVFLLGGSRKRVLVRVERATVYSVEQDNDLE 3058
Query: 2710 DFSTYYLGGI-----PIAIRERFNISTPAFRGCMKNLKKTSGVVRLN--DTVGVTKKCSE 2762
YYLGG+ P ++R F + + RGC+K +K V L +T GV+ C+
Sbjct: 3059 LADAYYLGGVPPDQLPPSLRRLFP-TGGSVRGCVKGIKALGKYVDLKRLNTTGVSAGCTA 3117
Query: 2763 DWKLVRSASFSRGGQLSFTDLGLPP-TDHLQASFGFQTFQPSGILLDHQTWTRNLQVTLE 2821
D + R+ +F G L + P T ++ + FGF + Q S +L + QV+L+
Sbjct: 3118 DLLVGRAMTFHGHGFLRLALSNVAPLTGNVYSGFGFHSAQDSALLYYRASPDGLCQVSLQ 3177
Query: 2822 DGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLLRNS------KRL 2875
G + L + K+ + DG HYV+ S+ +G+ L +DDQL + L
Sbjct: 3178 QGRVSLQLLRTE---VKTQAGFADGAPHYVAFYSNATGVWLYVDDQLQQMKPHRGPPPEL 3234
Query: 2876 KHISSSRQSLRLGG-------SNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLGGCS 2928
+ L LGG NF GCISNVFVQRL V DL N +VS GC+
Sbjct: 3235 QPQPEGPPRLLLGGLPESGTIYNFSGCISNVFVQRLLGPQRVFDLQQNLGSVNVST-GCA 3293
Query: 2929 LNKPPFLMLLKGSTRFNKTKTFRINQLLQDTPVASPRSVKVWQDACSPLPKTQANHGALQ 2988
P G T R P P AC P + + Q
Sbjct: 3294 ---PALQAQTPGLGPRGLQATARKASRRSRQPARHP--------ACMLPPHLRTTRDSYQ 3342
Query: 2989 FGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTG---TKNSFMALYLSKGRLV 3045
FG +SHL F + ++ + SSRGL+ T + +AL+LS G V
Sbjct: 3343 FGGSLSSHLEFVGILARHRNWPSLSMHVLPRSSRGLLLFTARLRPGSPSLALFLSNGHFV 3402
Query: 3046 FALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRA--REGSLPGNSTISIR 3103
+ G +LR +S+++ G+WH V + + LV DG RA +EG +
Sbjct: 3403 AQMEGLGTRLRAQSRQRSRPGRWHKVSVRWEKNRILLVTDGARAWSQEGPHRQHQGAEHP 3462
Query: 3104 APVYL---GSPPSGKPKSLP-TNSFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGI 3159
P L G P S LP T F GC+K +L +PL P+ GV+ C+ GPLE G+
Sbjct: 3463 QPHTLFVGGLPASSHSSKLPVTVGFSGCVKRLRLHGRPLGAPTRMAGVTPCILGPLEAGL 3522
Query: 3160 YFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIG-SQPGKHLCVYLEAGKVTAS 3218
+F GG + L P+ L +RP ++TG++ H+G ++ +L + + +V
Sbjct: 3523 FFPGSGGVITLDLPGATLPDVGLELEVRPLAVTGLIFHLGQARTPPYLQLQVTEKQVLLR 3582
Query: 3219 MDSGAGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEP 3278
D GAG STSVT LCDGQWH +AV ++L LE+D S++T G + A P
Sbjct: 3583 ADDGAGEFSTSVTRPSVLCDGQWHRLAVMKSGNVLRLEVDAQSNHTVGPLLAAAAGAPAP 3642
Query: 3279 LHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCP 3331
L+LGG P + P ++ GC+R + VN PV +T ++EV G V +GCP
Sbjct: 3643 LYLGGLPEPMAVQPWP--PAYCGCMRRLAVNRSPVAMTRSVEVHGAVGASGCP 3693
Score = 188 bits (478), Expect = 7e-47
Identities = 116/364 (31%), Positives = 153/364 (42%), Gaps = 65/364 (17%)
Query: 319 CECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASL 378
C C G++C C G+ +R C C CHGH+ C
Sbjct: 1831 CLCPASYRGDSCQECAPGF----YRDVKGLFLGRCVPCQCHGHSDRCL------------ 1874
Query: 379 NTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSC-----DPEHA 433
G GVC++CQHNT G +CE+C G+ P AP C+ C C A
Sbjct: 1875 ------PGSGVCVDCQHNTEGAHCERCQAGFVSSRDDP-SAP--CVSCPCPLSVPSNNFA 1925
Query: 434 DGCEQGSGR--CHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGC 491
+GC GR C CKP + G +CE+CA G++ P L P + DP ++
Sbjct: 1926 EGCVLRGGRTQCLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDP---NLLFS 1982
Query: 492 DCNLEGVLPEICDAHGRCL-CRPGVEGPRCDTCRSGFYSFPI----CQACWCSALGSYQM 546
DC+ G C C GPRC+ C GFY + C C C+ G+
Sbjct: 1983 DCD---------PLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTPCGTEA- 2032
Query: 547 PCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQG-SSSACDPA---GTINSNLGYCQCK 602
C +G C C+ GVTG+RCDRC G + F C G AC PA + G C C+
Sbjct: 2033 -CDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCHCR 2091
Query: 603 LHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDS 662
GP C C YW L ++ GC C+C G C G C+C + G+
Sbjct: 2092 PGTMGPQCRECAPGYWGLPEQ---GCRRCQC-------PGGRCDPHTGRCNCPPGLSGER 2141
Query: 663 CDTC 666
CDTC
Sbjct: 2142 CDTC 2145
Score = 170 bits (431), Expect = 2e-41
Identities = 117/375 (31%), Positives = 160/375 (42%), Gaps = 54/375 (14%)
Query: 371 VERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPY-GVPVDAPDGCIPCSCD 429
V + AS QG A C + G +C++CA G+YR G+ + C+PC C
Sbjct: 1811 VALEVASPAGQGALASNVELCLCPASYRGDSCQECAPGFYRDVKGLFLGR---CVPCQCH 1867
Query: 430 PEHADGCEQGSGRC-HCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDI 488
H+D C GSG C C+ N G +CE+C G+ + S +DP A +
Sbjct: 1868 G-HSDRCLPGSGVCVDCQHNTEGAHCERCQAGFVS---------------SRDDPSAPCV 1911
Query: 489 KGCDCNLE---GVLPEICDAHG---RCLCRPGVEGPRCDTCRSGFYSFPI-----CQACW 537
C C L E C G +CLC+PG G C+ C GF+ P+ CQ C
Sbjct: 1912 S-CPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCD 1970
Query: 538 CSALGSYQM---PCSSVTGQCE-CRPGVTGQRCDRCLSGAYDFPHCQGSSSACD--PAGT 591
CS G + C +TG C C TG RC+ C G Y G+ + CD P GT
Sbjct: 1971 CSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTPCGT 2030
Query: 592 --INSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGD 649
+ + G+C CK V G C RC+ ++ D GC C+ G + EC
Sbjct: 2031 EACDPHSGHCLCKAGVTGRRCDRCQEGHFGFD-----GCGGCRPCACGPAAEGSECHPQS 2085
Query: 650 GDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHV 709
G CHC+ G C C GY+ L + GC+ CQC G C +G C C +
Sbjct: 2086 GQCHCRPGTMGPQCRECAPGYWGLPEQ---GCRRCQCPGG-----RCDPHTGRCNCPPGL 2137
Query: 710 VGKVCQRPENNYYFP 724
G+ C + P
Sbjct: 2138 SGERCDTCSQQHQVP 2152
Score = 134 bits (338), Expect = 1e-30
Identities = 88/327 (26%), Positives = 121/327 (37%), Gaps = 73/327 (22%)
Query: 286 YYYSIKDISIGG--QCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWR 343
+Y +K + +G C C+GH++ C P +CQH+T G C+RC G+ R
Sbjct: 1849 FYRDVKGLFLGRCVPCQCHGHSDRCL---PGSGVCVDCQHNTEGAHCERCQAGFVSSRDD 1905
Query: 344 PAAWEQSHEC----------EACNCHGHASNCYYDPDVERQQASLNTQGIYAGG------ 387
P+A S C E C G + C P G +
Sbjct: 1906 PSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGASCERCAPGFFGNPLVLGSS 1965
Query: 388 -----------------------GVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCI 424
G C C +T G CE CA G+Y +P C
Sbjct: 1966 CQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLP----GNCT 2021
Query: 425 PCSCDPEHADGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPV 484
C C P + C+ SG C CK G C++C G++ F C
Sbjct: 2022 RCDCTPCGTEACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGC----------------- 2064
Query: 485 AGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPI--CQACWCSALG 542
G + C C E G+C CRPG GP+C C G++ P C+ C C
Sbjct: 2065 -GGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQGCRRCQCPG-- 2121
Query: 543 SYQMPCSSVTGQCECRPGVTGQRCDRC 569
C TG+C C PG++G+RCD C
Sbjct: 2122 ---GRCDPHTGRCNCPPGLSGERCDTC 2145
Score = 125 bits (315), Expect = 5e-28
Identities = 79/244 (32%), Positives = 102/244 (41%), Gaps = 35/244 (14%)
Query: 1243 TASRFCKNSARSLVAFYHKGALPCECHPTGATGPH------CSPEGG--QCPCQPNVIGR 1294
T C+ V+ + PC P + P C GG QC C+P G
Sbjct: 1887 TEGAHCERCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGA 1946
Query: 1295 QCTRCATGHYGFP-----RCKPCSCGRRL--------CEEMTGQCR-CPPRTVRPQCEVC 1340
C RCA G +G P C+PC C C+ +TG CR C T P+CE+C
Sbjct: 1947 SCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEIC 2006
Query: 1341 ETHSFSFHPMAG-CEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRF 1399
+ + G C C+C+ GT CD SG C CK +TGR+CDRC G + F
Sbjct: 2007 APGFYGNALLPGNCTRCDCTPCGT-----EACDPHSGHCLCKAGVTGRRCDRCQEGHFGF 2061
Query: 1400 P---ECVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSC 1456
C PC C E C P +G C C+ G +C C G + L +GC C
Sbjct: 2062 DGCGGCRPCACG-PAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPE---QGCRRC 2117
Query: 1457 FCFG 1460
C G
Sbjct: 2118 QCPG 2121
Score = 116 bits (291), Expect = 3e-25
Identities = 77/228 (33%), Positives = 93/228 (40%), Gaps = 32/228 (14%)
Query: 1264 LPCECHPTGATGPHCSPEGGQC-PCQPNVIGRQCTRCATGHYGF-----PRCKPCSCGRR 1317
+PC+CH C P G C CQ N G C RC G C C C
Sbjct: 1862 VPCQCH---GHSDRCLPGSGVCVDCQHNTEGAHCERCQAGFVSSRDDPSAPCVSCPCPLS 1918
Query: 1318 L--------CEEMTG--QCRCPPRTVRPQCEVCETHSFSFHPMAG--CEGCNCSRRGTIE 1365
+ C G QC C P CE C F + G C+ C+CS G
Sbjct: 1919 VPSNNFAEGCVLRGGRTQCLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPN 1978
Query: 1366 AAMPECDRDSGQCR-CKPRITGRQCDRCASGFYRFP----ECVPCNCNRDGTEPGVCDPG 1420
+CD +G CR C TG +C+ CA GFY C C+C GTE CDP
Sbjct: 1979 LLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTPCGTE--ACDPH 2036
Query: 1421 TGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFC--FGVNNQCH 1466
+G CLCK V G C+ C+EG F D GC C C ++CH
Sbjct: 2037 SGHCLCKAGVTGRRCDRCQEGHFGFDGCG--GCRPCACGPAAEGSECH 2082
Score = 114 bits (284), Expect = 2e-24
Identities = 63/189 (33%), Positives = 77/189 (40%), Gaps = 22/189 (11%)
Query: 1265 PCECHPTGATG---PHCSPEGGQCP-CQPNVIGRQCTRCATGHYG-------FPRCKPCS 1313
PC+C G C P G C C + G +C CA G YG RC
Sbjct: 1968 PCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTP 2027
Query: 1314 CGRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDR 1373
CG C+ +G C C +C+ C+ F F GC C C A EC
Sbjct: 2028 CGTEACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGCRPCACGPA----AEGSECHP 2083
Query: 1374 DSGQCRCKPRITGRQCDRCASGFYRFPE--CVPCNCNRDGTEPGVCDPGTGACLCKENVE 1431
SGQC C+P G QC CA G++ PE C C C G CDP TG C C +
Sbjct: 2084 QSGQCHCRPGTMGPQCRECAPGYWGLPEQGCRRCQC-----PGGRCDPHTGRCNCPPGLS 2138
Query: 1432 GTECNVCRE 1440
G C+ C +
Sbjct: 2139 GERCDTCSQ 2147
Score = 93.6 bits (231), Expect = 3e-18
Identities = 51/169 (30%), Positives = 74/169 (43%), Gaps = 22/169 (13%)
Query: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHS---NQCQDGSGICVNCQHNT 1710
C C P + G C+ C+PG+Y C PC C+ ++C +G C C+
Sbjct: 515 CLCKPNFQGTHCELCAPGFYGPG-------CQPCQCSSPGVADDRCDPDTGQC-RCRVGF 566
Query: 1711 AGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCA 1770
G C+RC GY+ + C+ C C + GC G RC C+ + G C+RC
Sbjct: 567 EGATCDRCAPGYFHFPL---CQLCGCSPAGTLPEGCDEAG---RCLCQPEFAGPHCDRCR 620
Query: 1771 PGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEEC 1819
PGY G P +CQ C+C+ G L G C + + +EC
Sbjct: 621 PGYHGFP-----NCQACTCDPRGALDQLCGAGGLCRCRPGYTGTACQEC 664
Score = 84.3 bits (207), Expect = 2e-15
Identities = 52/173 (30%), Positives = 73/173 (42%), Gaps = 23/173 (13%)
Query: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGE 1713
C C G C C+ GY+ C PC+C + C + +G C+ C T
Sbjct: 1457 CPCHAHVIGRDCSRCATGYWG------FPNCRPCDCG--ARLCDELTGQCI-CPPRTIPP 1507
Query: 1714 HCERCQEGYYGNAVHGSCRACPC--PHTNSFATG-CVVNGGDVRCSCKAGYTGTQCERCA 1770
C CQ +G C C C P C + G +C C+ TG +C+ C+
Sbjct: 1508 DCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSG--QCKCRPNVTGRRCDTCS 1565
Query: 1771 PGYFGNPQKFGGSCQPCSCNSNGQL-GSCHPLTGDCINQEPKDSSPAEECDDC 1822
PG+ G P+ C+PC C+ G G C PLTG C K++ +CD C
Sbjct: 1566 PGFHGYPR-----CRPCDCHEAGTAPGVCDPLTGQCY---CKENVQGPKCDQC 1610
Score = 83.6 bits (205), Expect = 3e-15
Identities = 34/81 (41%), Positives = 44/81 (54%), Gaps = 3/81 (3%)
Query: 1262 GALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPR--CKPCSCGRRLC 1319
G PC C P A G C P+ GQC C+P +G QC CA G++G P C+ C C C
Sbjct: 2066 GCRPCACGPA-AEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQGCRRCQCPGGRC 2124
Query: 1320 EEMTGQCRCPPRTVRPQCEVC 1340
+ TG+C CPP +C+ C
Sbjct: 2125 DPHTGRCNCPPGLSGERCDTC 2145
Score = 79.3 bits (194), Expect = 6e-14
Identities = 53/170 (31%), Positives = 72/170 (42%), Gaps = 35/170 (20%)
Query: 1682 GRCVPCNCNGHSNQCQ-----DGSGICVNCQHNTAGEHCERCQEGY----YGNAVHGSCR 1732
GRCV C+GH++ C D + CQHNT G C+RC G+ + A S
Sbjct: 298 GRCV---CHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSAN 354
Query: 1733 ACPCPHTNSFATGCVVN-----------------GGDVRCSCKAGYTGTQCERCAPGYFG 1775
C + AT C + GG V C+ TG CERC PG++
Sbjct: 355 ECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYR 414
Query: 1776 NPQKFGGS---CQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 1822
+P S C+ C+C S+ G+C LTG C + + E CD C
Sbjct: 415 SPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCY---CRPNFSGERCDVC 461
Score = 39.3 bits (90), Expect = 0.066
Identities = 18/63 (28%), Positives = 25/63 (39%), Gaps = 5/63 (7%)
Query: 1241 PQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCA 1300
P T C+ A +G C+C G C P G+C C P + G +C C+
Sbjct: 2092 PGTMGPQCRECAPGYWGLPEQGCRRCQC-----PGGRCDPHTGRCNCPPGLSGERCDTCS 2146
Query: 1301 TGH 1303
H
Sbjct: 2147 QQH 2149
>gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
Length = 1816
Score = 831 bits (2147), Expect = 0.0
Identities = 560/1816 (30%), Positives = 893/1816 (49%), Gaps = 157/1816 (8%)
Query: 1632 SEVGLEEASDTGSGRIALAVEICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNG 1691
S VG ++ +T R+AL PPA + C+ G++ +G CVPC+CNG
Sbjct: 40 SAVGRQDPPETSEPRVALG----RLPPA-----AEKCNAGFFHT----LSGECVPCDCNG 86
Query: 1692 HSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGS---CRACPCP--HTNSFATGC 1746
+SN+C DGSG CV+CQ NT GEHCE+C +GY G+++ G+ C+ CPCP H +FA C
Sbjct: 87 NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESC 146
Query: 1747 VVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQ----LGSCHPLT 1802
G VRC C Y G CERCAPGY+GNP G +C+ C C+ N C +T
Sbjct: 147 YRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVT 206
Query: 1803 GDCIN---------------------------------QEPKDSSPAEECDD-------C 1822
G C N P DS E ++ C
Sbjct: 207 GQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGECLEEGFEPPTGC 266
Query: 1823 DSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAIS 1882
D CV L + L + KS + +S+ A + + L+ +L + +
Sbjct: 267 DKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYA 326
Query: 1883 NHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLN-------NNVNRATQSAKELDV 1935
+I E + L + E L EK SRK Q + N+ ++ + A ++
Sbjct: 327 LRKIQINNAENTMKSLLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRD 386
Query: 1936 KIKNVIRNVHILLKQISGTDGEGNNVPSGDFSREWAEAQRMMRELRNRN---FGKHLREA 1992
KI+ + + GE + + + S + AQ+M+ E+R+R + L +
Sbjct: 387 KIQEINNKMLYY--------GEEHELSPKEISEKLVLAQKMLEEIRSRQPFFTQRELVDE 438
Query: 1993 EADKRESQLLLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQA 2052
EAD E+ LL++ +WQ+ H E L + + L++Y AKLSDL+ L +A + A
Sbjct: 439 EAD--EAYELLSQAESWQRLHN-ETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDA 495
Query: 2053 NGLNQENERALGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLA 2112
+N+ ++Q + + L+T+ SL + L ++ K +
Sbjct: 496 EDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIY 555
Query: 2113 ASLNEARQELSDKVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCA 2172
A ++ A+ EL K+ LS + LV+EA HA+ LQ+ A +L ++ + LV+ A
Sbjct: 556 AEIDGAKSELQVKLSNLSNLSH--DLVQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKA 613
Query: 2173 VDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKM 2232
+DA+ YENI+N + A + A A + ++ V + + S+ LLN+A+
Sbjct: 614 LDASNVYENIVNYVSEANETAEFALNTTDRIYDAV--SGIDTQIIYHKDESENLLNQARE 671
Query: 2233 TQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMV 2292
Q K + A+ + + + +K + T L+ L +RGD + ++ +
Sbjct: 672 LQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRLIT 731
Query: 2293 RKANDITDEVLDGLNPIQTDVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRK 2352
+AN T EV P+ ++ + + A+ A ++V LT +P L +
Sbjct: 732 EEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQ 791
Query: 2353 IESINQQLLPLGNISDNMDRIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKG 2412
+ ++ Q+ P N+S ++ RIRELI Q R ASK+ V M F+G+S VEV ++DLK
Sbjct: 792 LRTVEQKR-PASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLKA 850
Query: 2413 YTSLSLFLQRPNSR-ENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTCVYNLGDREAEL 2471
+TSLSL+++ P R E T + F++YLG+K+A ++Y+G+A+ + L VYNLG ++ E+
Sbjct: 851 FTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEI 910
Query: 2472 QVDQILTKSETKEAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNL 2531
+D S A VK +R+ + ++ T + SS E + + ++LL+L
Sbjct: 911 PLDSKPVSSWP--AYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDL 968
Query: 2532 DPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPC 2591
DPE+ VFYVGG P +FKLP+ L+ P + GC+EL LN +V+SLYNFK +N++ + PC
Sbjct: 969 DPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNMDPSTSVPC 1028
Query: 2592 RRRK-----EESDKNYFEGTGYARVPTQPH----APIPTFGQTIQTTVDRGLLFFAENGD 2642
R K + +F+G+GYA V + F ++T D GL+ NG
Sbjct: 1029 ARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGS 1088
Query: 2643 RFISLNIEDGKLMVRYK---------LNSELPKERGVGDAINNGRDHSIQIKIGKLQKRM 2693
F L + +G L V Y L L K + IN+ + H I I I K+M
Sbjct: 1089 MFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQ-----INDAKYHEISI-IYHNDKKM 1142
Query: 2694 WINVDVQNT-IIDGEVFD--FSTYYLGGIPIAIRERFNISTPA-----FRGCMKNL---K 2742
+ VD ++ +D E F+ Y+GG P I + + FRGCMK K
Sbjct: 1143 ILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQK 1202
Query: 2743 KTSGVVRLNDTVGVTKKCSEDWKLVRSASFSRGGQLSFTDLG-LPPTDHLQASFGFQTFQ 2801
K ++ +T+GV C ED + R A F+ GQ + + D + F F+T Q
Sbjct: 1203 KDFNLLEQTETLGVGYGCPEDSLISRRAYFN--GQSFIASIQKISFFDGFEGGFNFRTLQ 1260
Query: 2802 PSGILLDHQTWTRNLQVTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLR 2861
P+G+L + + + ++L++G + + G + + Y DGL H+V +
Sbjct: 1261 PNGLLFYYASGSDVFSISLDNGTVIMDVK--GIKVQSVDKQYNDGLSHFVISSVSPTRYE 1318
Query: 2862 LLIDDQLLRNSK----RLKHISSSRQSLRLGGS-------NFEGCISNVFVQRLSLSPEV 2910
L++D + + +++ +S + GGS NF GCISN + R+ EV
Sbjct: 1319 LIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEV 1378
Query: 2911 LDLTSNSLKRDVSLGGCSLNKPPFLMLLKGSTRFNKTKTFRINQ--LLQDTPVASPRSVK 2968
D + K SL C + P +L K +K K + + +D P P ++K
Sbjct: 1379 EDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALK 1438
Query: 2969 VWQ------DACSPLPKTQANHGALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSR 3022
+ + C +A A Q+G S F+ + +SQF++ ++T SS
Sbjct: 1439 LPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSH 1498
Query: 3023 GLVFHTGTK--NSFMALYLSKGRLVFALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKG 3080
G++F+ + N FM L+L+ GRLV+ KKL+I+S+EK NDG WH V+F + G
Sbjct: 1499 GMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSG 1558
Query: 3081 RLVVDGLRAREGSLPGN-STISIRAPVYLGSPPSGKP-KSLPTNS---FVGCLKNFQLDS 3135
RLV+DGLR E SLP +T I+ P+YLG GK K++ NS F GCL N QL+
Sbjct: 1559 RLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNG 1618
Query: 3136 KPLYTPSSSFGVSSCLGGPLEKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGIL 3195
+ + S +F V+ C GP+E G YFS EGG+VVL S +G +F++ F +RPRS +G L
Sbjct: 1619 ASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTL 1678
Query: 3196 IHIGSQPGKHLCVYLEAGKVTASMDSGAGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHL 3255
+H S G++L V+++ G+V +++G STSVTPKQSLCDG+WH + V +++ L
Sbjct: 1679 VHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQL 1738
Query: 3256 ELDTDSSYTAGQIPFPPASTQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPV 3315
++D++ ++ G + P +EP+ +GG P +L T R+ K F GC+R+ ++ PV
Sbjct: 1739 DVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSF 1798
Query: 3316 TEALEVQGPVSLNGCP 3331
++A V G VS+N CP
Sbjct: 1799 SKAALVSGAVSINSCP 1814
Score = 107 bits (268), Expect = 2e-22
Identities = 73/237 (30%), Positives = 99/237 (41%), Gaps = 58/237 (24%)
Query: 350 SHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGY 409
S EC C+C+G+++ C G G C++CQ NT G +CE+C GY
Sbjct: 76 SGECVPCDCNGNSNECL------------------DGSGYCVHCQRNTTGEHCEKCLDGY 117
Query: 410 YRPYGVPV-DAPDGCIPCSCDPEH----ADGC--EQGSGRCHCKPNFHGDNCEKCAIGYY 462
G + AP C PC C H A+ C + G+ RC C N+ G NCE+CA GYY
Sbjct: 118 I---GDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
Query: 463 NFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLE---GVLPEICD-AHGRCL-CRPGVEG 517
P + K CDC+ ++ E CD G+C C G
Sbjct: 175 GNPLL----------------IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTG 218
Query: 518 PRCDTCRSGFYS----FPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCL 570
+C+ C G+Y C C C PC SVTG+C CD+C+
Sbjct: 219 FKCERCAPGYYGDARIAKNCAVCNCGG-----GPCDSVTGECLEEGFEPPTGCDKCV 270
Score = 80.9 bits (198), Expect = 2e-14
Identities = 74/246 (30%), Positives = 100/246 (40%), Gaps = 66/246 (26%)
Query: 294 SIGGQCV---CNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQS 350
++ G+CV CNG++ C + + CQ +T GE C++C GY R A
Sbjct: 74 TLSGECVPCDCNGNSNECLDGSG---YCVHCQRNTTGEHCEKCLDGYIGDSIRGA----P 126
Query: 351 HECEACNC-----HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQC 405
C+ C C A +CY G V C N AG NCE+C
Sbjct: 127 QFCQPCPCPLPHLANFAESCY-----------------RKNGAVRCICNENYAGPNCERC 169
Query: 406 AKGYYRPYGVPVDAPDGCIPCSC----DPEHA-DGCEQGSGRC-HCKPNFHGDNCEKCAI 459
A GY YG P+ C C C DP + C++ +G+C +C N G CE+CA
Sbjct: 170 APGY---YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAP 226
Query: 460 GYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDA-HGRCLCRPGVEGP 518
GYY + +A + C+C G P CD+ G CL G E P
Sbjct: 227 GYY-----------------GDARIAKNCAVCNC---GGGP--CDSVTGECL-EEGFEPP 263
Query: 519 R-CDTC 523
CD C
Sbjct: 264 TGCDKC 269
Score = 71.2 bits (173), Expect = 2e-11
Identities = 70/266 (26%), Positives = 96/266 (36%), Gaps = 30/266 (11%)
Query: 1250 NSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATG--HYGFP 1307
++A S A A P + + A G PE + + +C G H
Sbjct: 18 SAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHTLSG 77
Query: 1308 RCKPCSCGRRL--CEEMTGQC-RCPPRTVRPQCEVCETHSFSFHPMAG----CEGCNCSR 1360
C PC C C + +G C C T CE C + + G C+ C C
Sbjct: 78 ECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKC-LDGYIGDSIRGAPQFCQPCPCPL 136
Query: 1361 RGTIEAAMPECDRDSG--QCRCKPRITGRQCDRCASGFYRFP-----ECVPCNCNRDGTE 1413
A C R +G +C C G C+RCA G+Y P C C+C+ ++
Sbjct: 137 PHLANFA-ESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCS-GNSD 194
Query: 1414 PGV----CDPGTGACL-CKENVEGTECNVCREGSFHLDPANLKGCTSCFCFG-----VNN 1463
P + CD TG C C N G +C C G ++ D K C C C G V
Sbjct: 195 PNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPG-YYGDARIAKNCAVCNCGGGPCDSVTG 253
Query: 1464 QCHSSHKRRTKFVDMLGWHLETADRV 1489
+C D W L A R+
Sbjct: 254 ECLEEGFEPPTGCDKCVWDLTDALRL 279
Score = 64.7 bits (156), Expect = 1e-09
Identities = 51/174 (29%), Positives = 66/174 (37%), Gaps = 33/174 (18%)
Query: 1243 TASRFCKNSARSLVAFYHKGALPCECHPTGATGPH-------CSPEGG--QCPCQPNVIG 1293
T C+ + +GA P C P PH C + G +C C N G
Sbjct: 105 TTGEHCEKCLDGYIGDSIRGA-PQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAG 163
Query: 1294 RQCTRCATGHYGFP-----RCKPCSCGRRL--------CEEMTGQCR-CPPRTVRPQCEV 1339
C RCA G+YG P CK C C C+E+TGQCR C T +CE
Sbjct: 164 PNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCER 223
Query: 1340 CETHSFSFHPMA-GCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRC 1392
C + +A C CNC CD +G+C + CD+C
Sbjct: 224 CAPGYYGDARIAKNCAVCNCGG--------GPCDSVTGECLEEGFEPPTGCDKC 269
Score = 63.5 bits (153), Expect = 3e-09
Identities = 52/210 (24%), Positives = 77/210 (36%), Gaps = 24/210 (11%)
Query: 518 PRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQC-ECRPGVTGQRCDRCLSGAYDF 576
P + C +GF+ + C G+ C +G C C+ TG+ C++CL G Y
Sbjct: 62 PAAEKCNAGFFHTLSGECVPCDCNGNSN-ECLDGSGYCVHCQRNTTGEHCEKCLDG-YIG 119
Query: 577 PHCQGSSSACDPAGTINSNLGY-------------CQCKLHVEGPTCSRCKLLYWNLDKE 623
+G+ C P +L C C + GP C RC Y+
Sbjct: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLL 179
Query: 624 NPSGCSECKCHKAGTVSGTGE-CRQGDGDC-HCKSHVGGDSCDTCEDGYFA----LEKSN 677
S C +C C + E C + G C +C + G C+ C GY+ +
Sbjct: 180 IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCA 239
Query: 678 YFGCQGCQCD--IGGALSSMCSGPSGVCQC 705
C G CD G L P+G +C
Sbjct: 240 VCNCGGGPCDSVTGECLEEGFEPPTGCDKC 269
Score = 51.6 bits (122), Expect = 1e-05
Identities = 31/102 (30%), Positives = 45/102 (44%), Gaps = 13/102 (12%)
Query: 628 CSECKCHKAGTVSGTGECRQGDGDC-HCKSHVGGDSCDTCEDGYF--ALEKSNYFGCQGC 684
C C C+ + EC G G C HC+ + G+ C+ C DGY ++ + F CQ C
Sbjct: 79 CVPCDCN-----GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQF-CQPC 132
Query: 685 QCDIG--GALSSMCSGPSGV--CQCREHVVGKVCQRPENNYY 722
C + + C +G C C E+ G C+R YY
Sbjct: 133 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
>gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
Length = 1816
Score = 831 bits (2147), Expect = 0.0
Identities = 560/1816 (30%), Positives = 893/1816 (49%), Gaps = 157/1816 (8%)
Query: 1632 SEVGLEEASDTGSGRIALAVEICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNG 1691
S VG ++ +T R+AL PPA + C+ G++ +G CVPC+CNG
Sbjct: 40 SAVGRQDPPETSEPRVALG----RLPPA-----AEKCNAGFFHT----LSGECVPCDCNG 86
Query: 1692 HSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGS---CRACPCP--HTNSFATGC 1746
+SN+C DGSG CV+CQ NT GEHCE+C +GY G+++ G+ C+ CPCP H +FA C
Sbjct: 87 NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESC 146
Query: 1747 VVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQ----LGSCHPLT 1802
G VRC C Y G CERCAPGY+GNP G +C+ C C+ N C +T
Sbjct: 147 YRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVT 206
Query: 1803 GDCIN---------------------------------QEPKDSSPAEECDD-------C 1822
G C N P DS E ++ C
Sbjct: 207 GQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGECLEEGFEPPTGC 266
Query: 1823 DSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAIS 1882
D CV L + L + KS + +S+ A + + L+ +L + +
Sbjct: 267 DKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYA 326
Query: 1883 NHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLN-------NNVNRATQSAKELDV 1935
+I E + L + E L EK SRK Q + N+ ++ + A ++
Sbjct: 327 LRKIQINNAENTMKSLLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRD 386
Query: 1936 KIKNVIRNVHILLKQISGTDGEGNNVPSGDFSREWAEAQRMMRELRNRN---FGKHLREA 1992
KI+ + + GE + + + S + AQ+M+ E+R+R + L +
Sbjct: 387 KIQEINNKMLYY--------GEEHELSPKEISEKLVLAQKMLEEIRSRQPFFTQRELVDE 438
Query: 1993 EADKRESQLLLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQA 2052
EAD E+ LL++ +WQ+ H E L + + L++Y AKLSDL+ L +A + A
Sbjct: 439 EAD--EAYELLSQAESWQRLHN-ETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDA 495
Query: 2053 NGLNQENERALGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLA 2112
+N+ ++Q + + L+T+ SL + L ++ K +
Sbjct: 496 EDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIY 555
Query: 2113 ASLNEARQELSDKVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCA 2172
A ++ A+ EL K+ LS + LV+EA HA+ LQ+ A +L ++ + LV+ A
Sbjct: 556 AEIDGAKSELQVKLSNLSNLSH--DLVQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKA 613
Query: 2173 VDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKM 2232
+DA+ YENI+N + A + A A + ++ V + + S+ LLN+A+
Sbjct: 614 LDASNVYENIVNYVSEANETAEFALNTTDRIYDAV--SGIDTQIIYHKDESENLLNQARE 671
Query: 2233 TQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMV 2292
Q K + A+ + + + +K + T L+ L +RGD + ++ +
Sbjct: 672 LQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRLIT 731
Query: 2293 RKANDITDEVLDGLNPIQTDVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRK 2352
+AN T EV P+ ++ + + A+ A ++V LT +P L +
Sbjct: 732 EEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQ 791
Query: 2353 IESINQQLLPLGNISDNMDRIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKG 2412
+ ++ Q+ P N+S ++ RIRELI Q R ASK+ V M F+G+S VEV ++DLK
Sbjct: 792 LRTVEQKR-PASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLKA 850
Query: 2413 YTSLSLFLQRPNSR-ENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTCVYNLGDREAEL 2471
+TSLSL+++ P R E T + F++YLG+K+A ++Y+G+A+ + L VYNLG ++ E+
Sbjct: 851 FTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEI 910
Query: 2472 QVDQILTKSETKEAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNL 2531
+D S A VK +R+ + ++ T + SS E + + ++LL+L
Sbjct: 911 PLDSKPVSSWP--AYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDL 968
Query: 2532 DPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPC 2591
DPE+ VFYVGG P +FKLP+ L+ P + GC+EL LN +V+SLYNFK +N++ + PC
Sbjct: 969 DPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNMDPSTSVPC 1028
Query: 2592 RRRK-----EESDKNYFEGTGYARVPTQPH----APIPTFGQTIQTTVDRGLLFFAENGD 2642
R K + +F+G+GYA V + F ++T D GL+ NG
Sbjct: 1029 ARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGS 1088
Query: 2643 RFISLNIEDGKLMVRYK---------LNSELPKERGVGDAINNGRDHSIQIKIGKLQKRM 2693
F L + +G L V Y L L K + IN+ + H I I I K+M
Sbjct: 1089 MFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQ-----INDAKYHEISI-IYHNDKKM 1142
Query: 2694 WINVDVQNT-IIDGEVFD--FSTYYLGGIPIAIRERFNISTPA-----FRGCMKNL---K 2742
+ VD ++ +D E F+ Y+GG P I + + FRGCMK K
Sbjct: 1143 ILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQK 1202
Query: 2743 KTSGVVRLNDTVGVTKKCSEDWKLVRSASFSRGGQLSFTDLG-LPPTDHLQASFGFQTFQ 2801
K ++ +T+GV C ED + R A F+ GQ + + D + F F+T Q
Sbjct: 1203 KDFNLLEQTETLGVGYGCPEDSLISRRAYFN--GQSFIASIQKISFFDGFEGGFNFRTLQ 1260
Query: 2802 PSGILLDHQTWTRNLQVTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLR 2861
P+G+L + + + ++L++G + + G + + Y DGL H+V +
Sbjct: 1261 PNGLLFYYASGSDVFSISLDNGTVIMDVK--GIKVQSVDKQYNDGLSHFVISSVSPTRYE 1318
Query: 2862 LLIDDQLLRNSK----RLKHISSSRQSLRLGGS-------NFEGCISNVFVQRLSLSPEV 2910
L++D + + +++ +S + GGS NF GCISN + R+ EV
Sbjct: 1319 LIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEV 1378
Query: 2911 LDLTSNSLKRDVSLGGCSLNKPPFLMLLKGSTRFNKTKTFRINQ--LLQDTPVASPRSVK 2968
D + K SL C + P +L K +K K + + +D P P ++K
Sbjct: 1379 EDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALK 1438
Query: 2969 VWQ------DACSPLPKTQANHGALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSR 3022
+ + C +A A Q+G S F+ + +SQF++ ++T SS
Sbjct: 1439 LPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSH 1498
Query: 3023 GLVFHTGTK--NSFMALYLSKGRLVFALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKG 3080
G++F+ + N FM L+L+ GRLV+ KKL+I+S+EK NDG WH V+F + G
Sbjct: 1499 GMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSG 1558
Query: 3081 RLVVDGLRAREGSLPGN-STISIRAPVYLGSPPSGKP-KSLPTNS---FVGCLKNFQLDS 3135
RLV+DGLR E SLP +T I+ P+YLG GK K++ NS F GCL N QL+
Sbjct: 1559 RLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNG 1618
Query: 3136 KPLYTPSSSFGVSSCLGGPLEKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGIL 3195
+ + S +F V+ C GP+E G YFS EGG+VVL S +G +F++ F +RPRS +G L
Sbjct: 1619 ASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTL 1678
Query: 3196 IHIGSQPGKHLCVYLEAGKVTASMDSGAGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHL 3255
+H S G++L V+++ G+V +++G STSVTPKQSLCDG+WH + V +++ L
Sbjct: 1679 VHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQL 1738
Query: 3256 ELDTDSSYTAGQIPFPPASTQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPV 3315
++D++ ++ G + P +EP+ +GG P +L T R+ K F GC+R+ ++ PV
Sbjct: 1739 DVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSF 1798
Query: 3316 TEALEVQGPVSLNGCP 3331
++A V G VS+N CP
Sbjct: 1799 SKAALVSGAVSINSCP 1814
Score = 107 bits (268), Expect = 2e-22
Identities = 73/237 (30%), Positives = 99/237 (41%), Gaps = 58/237 (24%)
Query: 350 SHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGY 409
S EC C+C+G+++ C G G C++CQ NT G +CE+C GY
Sbjct: 76 SGECVPCDCNGNSNECL------------------DGSGYCVHCQRNTTGEHCEKCLDGY 117
Query: 410 YRPYGVPV-DAPDGCIPCSCDPEH----ADGC--EQGSGRCHCKPNFHGDNCEKCAIGYY 462
G + AP C PC C H A+ C + G+ RC C N+ G NCE+CA GYY
Sbjct: 118 I---GDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
Query: 463 NFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLE---GVLPEICD-AHGRCL-CRPGVEG 517
P + K CDC+ ++ E CD G+C C G
Sbjct: 175 GNPLL----------------IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTG 218
Query: 518 PRCDTCRSGFYS----FPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCL 570
+C+ C G+Y C C C PC SVTG+C CD+C+
Sbjct: 219 FKCERCAPGYYGDARIAKNCAVCNCGG-----GPCDSVTGECLEEGFEPPTGCDKCV 270
Score = 80.9 bits (198), Expect = 2e-14
Identities = 74/246 (30%), Positives = 100/246 (40%), Gaps = 66/246 (26%)
Query: 294 SIGGQCV---CNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQS 350
++ G+CV CNG++ C + + CQ +T GE C++C GY R A
Sbjct: 74 TLSGECVPCDCNGNSNECLDGSG---YCVHCQRNTTGEHCEKCLDGYIGDSIRGA----P 126
Query: 351 HECEACNC-----HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQC 405
C+ C C A +CY G V C N AG NCE+C
Sbjct: 127 QFCQPCPCPLPHLANFAESCY-----------------RKNGAVRCICNENYAGPNCERC 169
Query: 406 AKGYYRPYGVPVDAPDGCIPCSC----DPEHA-DGCEQGSGRC-HCKPNFHGDNCEKCAI 459
A GY YG P+ C C C DP + C++ +G+C +C N G CE+CA
Sbjct: 170 APGY---YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAP 226
Query: 460 GYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDA-HGRCLCRPGVEGP 518
GYY + +A + C+C G P CD+ G CL G E P
Sbjct: 227 GYY-----------------GDARIAKNCAVCNC---GGGP--CDSVTGECL-EEGFEPP 263
Query: 519 R-CDTC 523
CD C
Sbjct: 264 TGCDKC 269
Score = 71.2 bits (173), Expect = 2e-11
Identities = 70/266 (26%), Positives = 96/266 (36%), Gaps = 30/266 (11%)
Query: 1250 NSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATG--HYGFP 1307
++A S A A P + + A G PE + + +C G H
Sbjct: 18 SAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHTLSG 77
Query: 1308 RCKPCSCGRRL--CEEMTGQC-RCPPRTVRPQCEVCETHSFSFHPMAG----CEGCNCSR 1360
C PC C C + +G C C T CE C + + G C+ C C
Sbjct: 78 ECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKC-LDGYIGDSIRGAPQFCQPCPCPL 136
Query: 1361 RGTIEAAMPECDRDSG--QCRCKPRITGRQCDRCASGFYRFP-----ECVPCNCNRDGTE 1413
A C R +G +C C G C+RCA G+Y P C C+C+ ++
Sbjct: 137 PHLANFA-ESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCS-GNSD 194
Query: 1414 PGV----CDPGTGACL-CKENVEGTECNVCREGSFHLDPANLKGCTSCFCFG-----VNN 1463
P + CD TG C C N G +C C G ++ D K C C C G V
Sbjct: 195 PNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPG-YYGDARIAKNCAVCNCGGGPCDSVTG 253
Query: 1464 QCHSSHKRRTKFVDMLGWHLETADRV 1489
+C D W L A R+
Sbjct: 254 ECLEEGFEPPTGCDKCVWDLTDALRL 279
Score = 64.7 bits (156), Expect = 1e-09
Identities = 51/174 (29%), Positives = 66/174 (37%), Gaps = 33/174 (18%)
Query: 1243 TASRFCKNSARSLVAFYHKGALPCECHPTGATGPH-------CSPEGG--QCPCQPNVIG 1293
T C+ + +GA P C P PH C + G +C C N G
Sbjct: 105 TTGEHCEKCLDGYIGDSIRGA-PQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAG 163
Query: 1294 RQCTRCATGHYGFP-----RCKPCSCGRRL--------CEEMTGQCR-CPPRTVRPQCEV 1339
C RCA G+YG P CK C C C+E+TGQCR C T +CE
Sbjct: 164 PNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCER 223
Query: 1340 CETHSFSFHPMA-GCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRC 1392
C + +A C CNC CD +G+C + CD+C
Sbjct: 224 CAPGYYGDARIAKNCAVCNCGG--------GPCDSVTGECLEEGFEPPTGCDKC 269
Score = 63.5 bits (153), Expect = 3e-09
Identities = 52/210 (24%), Positives = 77/210 (36%), Gaps = 24/210 (11%)
Query: 518 PRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQC-ECRPGVTGQRCDRCLSGAYDF 576
P + C +GF+ + C G+ C +G C C+ TG+ C++CL G Y
Sbjct: 62 PAAEKCNAGFFHTLSGECVPCDCNGNSN-ECLDGSGYCVHCQRNTTGEHCEKCLDG-YIG 119
Query: 577 PHCQGSSSACDPAGTINSNLGY-------------CQCKLHVEGPTCSRCKLLYWNLDKE 623
+G+ C P +L C C + GP C RC Y+
Sbjct: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLL 179
Query: 624 NPSGCSECKCHKAGTVSGTGE-CRQGDGDC-HCKSHVGGDSCDTCEDGYFA----LEKSN 677
S C +C C + E C + G C +C + G C+ C GY+ +
Sbjct: 180 IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCA 239
Query: 678 YFGCQGCQCD--IGGALSSMCSGPSGVCQC 705
C G CD G L P+G +C
Sbjct: 240 VCNCGGGPCDSVTGECLEEGFEPPTGCDKC 269
Score = 51.6 bits (122), Expect = 1e-05
Identities = 31/102 (30%), Positives = 45/102 (44%), Gaps = 13/102 (12%)
Query: 628 CSECKCHKAGTVSGTGECRQGDGDC-HCKSHVGGDSCDTCEDGYF--ALEKSNYFGCQGC 684
C C C+ + EC G G C HC+ + G+ C+ C DGY ++ + F CQ C
Sbjct: 79 CVPCDCN-----GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQF-CQPC 132
Query: 685 QCDIG--GALSSMCSGPSGV--CQCREHVVGKVCQRPENNYY 722
C + + C +G C C E+ G C+R YY
Sbjct: 133 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
>gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens]
Length = 1823
Score = 830 bits (2143), Expect = 0.0
Identities = 560/1824 (30%), Positives = 896/1824 (49%), Gaps = 166/1824 (9%)
Query: 1632 SEVGLEEASDTGSGRIALAVEICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNG 1691
S VG ++ +T R+AL PPA + C+ G++ +G CVPC+CNG
Sbjct: 40 SAVGRQDPPETSEPRVALG----RLPPA-----AEKCNAGFFHT----LSGECVPCDCNG 86
Query: 1692 HSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGS---CRACPCP--HTNSFATGC 1746
+SN+C DGSG CV+CQ NT GEHCE+C +GY G+++ G+ C+ CPCP H +FA C
Sbjct: 87 NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESC 146
Query: 1747 VVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSN-------------- 1792
G VRC C Y G CERCAPGY+GNP G +C+ C C+ N
Sbjct: 147 YRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVT 206
Query: 1793 GQL------------------------------------GSCHPLTGDCINQEPKDSSPA 1816
GQ G C +TG+C+ +E +
Sbjct: 207 GQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGECL-EEGFEPPTG 265
Query: 1817 EECD--DCDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQL 1874
+C CD CV L + L + KS + +S+ A + + L+ +L
Sbjct: 266 MDCPTISCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKL 325
Query: 1875 LNYRSAISNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLN-------NNVNRAT 1927
+ + +I E + L + E L EK SRK Q + N+ ++
Sbjct: 326 SERENQYALRKIQINNAENTMKSLLSDVEELVEKENQASRKGQLVQKESMDTINHASQLV 385
Query: 1928 QSAKELDVKIKNVIRNVHILLKQISGTDGEGNNVPSGDFSREWAEAQRMMRELRNRN--- 1984
+ A ++ KI+ + + GE + + + S + AQ+M+ E+R+R
Sbjct: 386 EQAHDMRDKIQEINNKMLYY--------GEEHELSPKEISEKLVLAQKMLEEIRSRQPFF 437
Query: 1985 FGKHLREAEADKRESQLLLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQE 2044
+ L + EAD E+ LL++ +WQ+ H E L + + L++Y AKLSDL+ L +
Sbjct: 438 TQRELVDEEAD--EAYELLSQAESWQRLHN-ETRTLFPVVLEQLDDYNAKLSDLQEALDQ 494
Query: 2045 AAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKS 2104
A + A +N+ ++Q + + L+T+ SL + L ++
Sbjct: 495 ALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDI 554
Query: 2105 QKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNAS 2164
K + A ++ A+ EL K+ LS + LV+EA HA+ LQ+ A +L ++
Sbjct: 555 IKNASGIYAEIDGAKSELQVKLSNLSNLSH--DLVQEAIDHAQDLQQEANELSRKLHSSD 612
Query: 2165 GDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSD 2224
+ LV+ A+DA+ YENI+N + A + A A + ++ V + + S+
Sbjct: 613 MNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAV--SGIDTQIIYHKDESE 670
Query: 2225 KLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAM 2284
LLN+A+ Q K + A+ + + + +K + T L+ L +RGD
Sbjct: 671 NLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQR 730
Query: 2285 ISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQNEDFKKALTDADNSVNKLTN 2344
+ ++ + +AN T EV P+ ++ + + A+ A ++V LT
Sbjct: 731 LGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRNLTE 790
Query: 2345 KLPDLWRKIESINQQLLPLGNISDNMDRIRELIQQARDAASKVAVPMRFNGKSGVEVRLP 2404
+P L ++ ++ Q+ P N+S ++ RIRELI Q R ASK+ V M F+G+S VEV
Sbjct: 791 VVPQLLDQLRTVEQKR-PASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVHSR 849
Query: 2405 NDLEDLKGYTSLSLFLQRPNSR-ENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTCVYN 2463
++DLK +TSLSL+++ P R E T + F++YLG+K+A ++Y+G+A+ + L VYN
Sbjct: 850 TSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYN 909
Query: 2464 LGDREAELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGR 2523
LG ++ E+ +D S A VK +R+ + ++ T + SS E + +
Sbjct: 910 LGTKDVEIPLDSKPVSSWP--AYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFS 967
Query: 2524 NSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNL 2583
++LL+LDPE+ VFYVGG P +FKLP+ L+ P + GC+EL LN +V+SLYNFK +N+
Sbjct: 968 GDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNM 1027
Query: 2584 NTTEVEPCRRRK-----EESDKNYFEGTGYARVPTQPH----APIPTFGQTIQTTVDRGL 2634
+ + PC R K + +F+G+GYA V + F ++T D GL
Sbjct: 1028 DPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGL 1087
Query: 2635 LFFAENGDRFISLNIEDGKLMVRYK---------LNSELPKERGVGDAINNGRDHSIQIK 2685
+ NG F L + +G L V Y L L K + IN+ + H I I
Sbjct: 1088 ILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQ-----INDAKYHEISI- 1141
Query: 2686 IGKLQKRMWINVDVQNT-IIDGEVFD--FSTYYLGGIPIAIRERFNISTPA-----FRGC 2737
I K+M + VD ++ +D E F+ Y+GG P I + + FRGC
Sbjct: 1142 IYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGC 1201
Query: 2738 MKNL---KKTSGVVRLNDTVGVTKKCSEDWKLVRSASFSRGGQLSFTDLG-LPPTDHLQA 2793
MK KK ++ +T+GV C ED + R A F+ GQ + + D +
Sbjct: 1202 MKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFN--GQSFIASIQKISFFDGFEG 1259
Query: 2794 SFGFQTFQPSGILLDHQTWTRNLQVTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSV 2853
F F+T QP+G+L + + + ++L++G + + G + + Y DGL H+V
Sbjct: 1260 GFNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVK--GIKVQSVDKQYNDGLSHFVIS 1317
Query: 2854 ISDNSGLRLLIDDQLLRNSK----RLKHISSSRQSLRLGGS-------NFEGCISNVFVQ 2902
+ L++D + + +++ +S + GGS NF GCISN +
Sbjct: 1318 SVSPTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFT 1377
Query: 2903 RLSLSPEVLDLTSNSLKRDVSLGGCSLNKPPFLMLLKGSTRFNKTKTFRINQ--LLQDTP 2960
R+ EV D + K SL C + P +L K +K K + + +D P
Sbjct: 1378 RVDRDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAP 1437
Query: 2961 VASPRSVKVWQ------DACSPLPKTQANHGALQFGDIPTSHLLFKLPQELLKPRSQFAV 3014
P ++K+ + C +A A Q+G S F+ + +SQF++
Sbjct: 1438 SWDPVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSI 1497
Query: 3015 DMQTTSSRGLVFHTGTK--NSFMALYLSKGRLVFALGTDGKKLRIKSKEKCNDGKWHTVV 3072
++T SS G++F+ + N FM L+L+ GRLV+ KKL+I+S+EK NDG WH V+
Sbjct: 1498 RLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVI 1557
Query: 3073 FGHDGEKGRLVVDGLRAREGSLPGN-STISIRAPVYLGSPPSGKP-KSLPTNS---FVGC 3127
F + GRLV+DGLR E SLP +T I+ P+YLG GK K++ NS F GC
Sbjct: 1558 FIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGC 1617
Query: 3128 LKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIR 3187
L N QL+ + + S +F V+ C GP+E G YFS EGG+VVL S +G +F++ F +R
Sbjct: 1618 LSNLQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVR 1677
Query: 3188 PRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGGTSTSVTPKQSLCDGQWHSVAVT 3247
PRS +G L+H S G++L V+++ G+V +++G STSVTPKQSLCDG+WH + V
Sbjct: 1678 PRSSSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVI 1737
Query: 3248 IKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIH 3307
+++ L++D++ ++ G + P +EP+ +GG P +L T R+ K F GC+R+
Sbjct: 1738 RDSNVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFV 1797
Query: 3308 VNHIPVPVTEALEVQGPVSLNGCP 3331
++ PV ++A V G VS+N CP
Sbjct: 1798 IDGHPVSFSKAALVSGAVSINSCP 1821
Score = 105 bits (263), Expect = 6e-22
Identities = 76/244 (31%), Positives = 102/244 (41%), Gaps = 65/244 (26%)
Query: 350 SHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGY 409
S EC C+C+G+++ C G G C++CQ NT G +CE+C GY
Sbjct: 76 SGECVPCDCNGNSNECL------------------DGSGYCVHCQRNTTGEHCEKCLDGY 117
Query: 410 YRPYGVPV-DAPDGCIPCSCDPEH----ADGC--EQGSGRCHCKPNFHGDNCEKCAIGYY 462
G + AP C PC C H A+ C + G+ RC C N+ G NCE+CA GYY
Sbjct: 118 I---GDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
Query: 463 NFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLE---GVLPEICD-AHGRCL-CRPGVEG 517
P + K CDC+ ++ E CD G+C C G
Sbjct: 175 GNPLL----------------IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTG 218
Query: 518 PRCDTCRSGFYS----FPICQACWCSALGSYQMPCSSVTGQC--ECRPGVTGQ-----RC 566
+C+ C G+Y C C C PC SVTG+C E TG C
Sbjct: 219 FKCERCAPGYYGDARIAKNCAVCNCGG-----GPCDSVTGECLEEGFEPPTGMDCPTISC 273
Query: 567 DRCL 570
D+C+
Sbjct: 274 DKCV 277
Score = 80.1 bits (196), Expect = 3e-14
Identities = 58/183 (31%), Positives = 79/183 (43%), Gaps = 41/183 (22%)
Query: 294 SIGGQCV---CNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQS 350
++ G+CV CNG++ C + + CQ +T GE C++C GY R A
Sbjct: 74 TLSGECVPCDCNGNSNECLDGSG---YCVHCQRNTTGEHCEKCLDGYIGDSIRGA----P 126
Query: 351 HECEACNC-----HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQC 405
C+ C C A +CY G V C N AG NCE+C
Sbjct: 127 QFCQPCPCPLPHLANFAESCY-----------------RKNGAVRCICNENYAGPNCERC 169
Query: 406 AKGYYRPYGVPVDAPDGCIPCSC----DPEHA-DGCEQGSGRC-HCKPNFHGDNCEKCAI 459
A GY YG P+ C C C DP + C++ +G+C +C N G CE+CA
Sbjct: 170 APGY---YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAP 226
Query: 460 GYY 462
GYY
Sbjct: 227 GYY 229
Score = 70.5 bits (171), Expect = 3e-11
Identities = 63/232 (27%), Positives = 87/232 (37%), Gaps = 25/232 (10%)
Query: 1250 NSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATG--HYGFP 1307
++A S A A P + + A G PE + + +C G H
Sbjct: 18 SAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHTLSG 77
Query: 1308 RCKPCSCGRRL--CEEMTGQC-RCPPRTVRPQCEVCETHSFSFHPMAG----CEGCNCSR 1360
C PC C C + +G C C T CE C + + G C+ C C
Sbjct: 78 ECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKC-LDGYIGDSIRGAPQFCQPCPCPL 136
Query: 1361 RGTIEAAMPECDRDSG--QCRCKPRITGRQCDRCASGFYRFP-----ECVPCNCNRDGTE 1413
A C R +G +C C G C+RCA G+Y P C C+C+ ++
Sbjct: 137 PHLANFA-ESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCS-GNSD 194
Query: 1414 PGV----CDPGTGACL-CKENVEGTECNVCREGSFHLDPANLKGCTSCFCFG 1460
P + CD TG C C N G +C C G ++ D K C C C G
Sbjct: 195 PNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPG-YYGDARIAKNCAVCNCGG 245
Score = 63.2 bits (152), Expect = 4e-09
Identities = 50/174 (28%), Positives = 66/174 (37%), Gaps = 26/174 (14%)
Query: 1243 TASRFCKNSARSLVAFYHKGALPCECHPTGATGPH-------CSPEGG--QCPCQPNVIG 1293
T C+ + +GA P C P PH C + G +C C N G
Sbjct: 105 TTGEHCEKCLDGYIGDSIRGA-PQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAG 163
Query: 1294 RQCTRCATGHYGFP-----RCKPCSCGRRL--------CEEMTGQCR-CPPRTVRPQCEV 1339
C RCA G+YG P CK C C C+E+TGQCR C T +CE
Sbjct: 164 PNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCER 223
Query: 1340 CETHSFSFHPMA-GCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRC 1392
C + +A C CNC G ++ EC + + CD+C
Sbjct: 224 CAPGYYGDARIAKNCAVCNCG-GGPCDSVTGECLEEGFEPPTGMDCPTISCDKC 276
Score = 62.4 bits (150), Expect = 7e-09
Identities = 51/202 (25%), Positives = 75/202 (37%), Gaps = 24/202 (11%)
Query: 518 PRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQC-ECRPGVTGQRCDRCLSGAYDF 576
P + C +GF+ + C G+ C +G C C+ TG+ C++CL G Y
Sbjct: 62 PAAEKCNAGFFHTLSGECVPCDCNGNSN-ECLDGSGYCVHCQRNTTGEHCEKCLDG-YIG 119
Query: 577 PHCQGSSSACDPAGTINSNLGY-------------CQCKLHVEGPTCSRCKLLYWNLDKE 623
+G+ C P +L C C + GP C RC Y+
Sbjct: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLL 179
Query: 624 NPSGCSECKCHKAGTVSGTGE-CRQGDGDC-HCKSHVGGDSCDTCEDGYFALEKSNYFGC 681
S C +C C + E C + G C +C + G C+ C GY+ + C
Sbjct: 180 IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNC 238
Query: 682 QGCQCDIGGALSSMCSGPSGVC 703
C C GG C +G C
Sbjct: 239 AVCNC--GG---GPCDSVTGEC 255
Score = 51.6 bits (122), Expect = 1e-05
Identities = 31/102 (30%), Positives = 45/102 (44%), Gaps = 13/102 (12%)
Query: 628 CSECKCHKAGTVSGTGECRQGDGDC-HCKSHVGGDSCDTCEDGYF--ALEKSNYFGCQGC 684
C C C+ + EC G G C HC+ + G+ C+ C DGY ++ + F CQ C
Sbjct: 79 CVPCDCN-----GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQF-CQPC 132
Query: 685 QCDIG--GALSSMCSGPSGV--CQCREHVVGKVCQRPENNYY 722
C + + C +G C C E+ G C+R YY
Sbjct: 133 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
sapiens]
Length = 3118
Score = 645 bits (1663), Expect = 0.0
Identities = 591/2246 (26%), Positives = 960/2246 (42%), Gaps = 266/2246 (11%)
Query: 1261 KGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPR--CKPCSCGR-- 1316
+G +PC C+ G+ C E GQC CQP V G++C RCA G++ F C C C
Sbjct: 962 RGCVPCNCNSFGSKSFDCE-ESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLG 1020
Query: 1317 RLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSG 1376
C+ TG+C CPP T+ +C C +++ GC+ CNCS G+++ +C+ ++G
Sbjct: 1021 NNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDF---QCNVNTG 1077
Query: 1377 QCRCKPRITGRQCDRCASGFYRFPECVPCNCNRDGTEPGVCDPGT---------GACLCK 1427
QC C P+ +G +C C+ G + +P C C+C GT+ CD T G C CK
Sbjct: 1078 QCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCK 1137
Query: 1428 ENVEGTECNVCREGSFHLDPANLKGCTSCFCFGVNNQCHSSHKRRTKFVDMLGWHLETAD 1487
NVEG C+ CR G F LD N GC+SC+CFG QC + +V + A+
Sbjct: 1138 VNVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTWVTL------KAE 1191
Query: 1488 RVDIPVSFNPGSNS-----------MVADLQELPATIHSAS--WVAPTSYLGDKVSSYGG 1534
+ +P+ ++ +VA + + +H W P + G K+ +YGG
Sbjct: 1192 QTILPLVDEALQHTTTKGIVFQHPEIVAHMDLMREDLHLEPFYWKLPEQFEGKKLMAYGG 1251
Query: 1535 YLTYQAKSFGLPGDMVLLEKKPDVQLTG---QHMSIIYEETNTPRPDRLHHGRVHVVEGN 1591
L Y A F + P V + G H II P +L + + E
Sbjct: 1252 KLKY-AIYFEAREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTRHEIEMTEKE 1310
Query: 1592 FRHASS----RAPVSREELMTVLSRLADVRIQGLYFTETQRLTLSEVGLEEASDTGSGRI 1647
+++ V+RE+ + +L + + I+ Y ++ +SE+ +E A + G G
Sbjct: 1311 WKYYGDDPRVHRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEVA-EQGRGTT 1369
Query: 1648 ----ALAVEICACPPAYAGDSCQGCSPGYYRDHK-------GLYTGRCVPCNCNGHSNQC 1696
A +E C CP Y+G SC+ C PG+YR G G CVPC CNGHS+ C
Sbjct: 1370 MTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLC 1429
Query: 1697 QDGSGICVNCQHNTAGEHCERCQEGYYG--NAVHGSCRACPCP---HTNSFATGCVVNG- 1750
+ IC NCQH+TAG+ CERC GYYG + C+ C CP +N+F+ CV G
Sbjct: 1430 DPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGL 1489
Query: 1751 GDVRC-SCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLG-SCHPLTGDCINQ 1808
D RC +C GY G CERCAPGY G+P GGSCQ C C+ G L C P+TG C
Sbjct: 1490 DDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFC--- 1546
Query: 1809 EPKDSSPAEECDDC---------------DSCVMTLLNDLATMGEQLRLVKSQLQGLSAS 1853
+ + +CD C D C LL DLA + EQ+ + + L A
Sbjct: 1547 TCRPGATGRKCDGCKHWHAREGWECVFCGDECTGLLLGDLARL-EQMVMSINLTGPLPAP 1605
Query: 1854 AGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEG-LERELTDLNQEFETLQEKAQVN 1912
+L + +M + K LL+ + A EG L +T++N E L +V
Sbjct: 1606 YKMLYGLENMTQELK----HLLSPQRAPERLIQLAEGNLNTLVTEMN---ELLTRATKVT 1658
Query: 1913 SRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHILLK---QISGTDGEGNNVPSGDFSRE 1969
+ QT + R AK L IK + R+ + + +++ T G + +
Sbjct: 1659 ADGEQT-GQDAERTNTRAKSLGEFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGL 1717
Query: 1970 WAEAQRMMRELRNRNFGKHLREAEADKRESQLLLNRIRTWQKTHQGENNGLANSIRDSLN 2029
E +M++ELR +N AE + ++ LL +++ +GEN + +R+ L
Sbjct: 1718 QKEIDQMIKELRRKNLETQKEIAEDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLA 1777
Query: 2030 EYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLTTADS 2089
+Y+ K+ D L+EA + ++AN L N++ + A++++ + + S + L +
Sbjct: 1778 DYKNKVDDAWDLLREATDKIREANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGND 1837
Query: 2090 SLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVE---EAEKHA 2146
L + N + E + L +EL+DK+ +LS+ L E +AE HA
Sbjct: 1838 ILDEANRLADEINSIIDYVEDIQTKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHA 1897
Query: 2147 RSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESA--L 2204
L + + L+ I A + A A AY NI + I AE A A + A L
Sbjct: 1898 AQLNDSSAVLDGILDEAK--NISFNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKL 1955
Query: 2205 QTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDT 2264
T + L AK S ++LNEAK +K E LN L+ + + +
Sbjct: 1956 ATGPRGLLKEDAKGCLQKSFRILNEAKKLANDVK-ENEDHLNGLKTRIENADARNGDL-- 2012
Query: 2265 NLTTLRDGLHGIQR--GDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGR 2322
L TL D L + D A + + K R+AND +VL + + +++ +K Y +
Sbjct: 2013 -LRTLNDTLGKLSAIPNDTAAKLQAVKDKARQANDTAKDVLAQITELHQNLDGLKKNYNK 2071
Query: 2323 TQNEDFK-----------KALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNMD 2371
+ K K + DAD +V L + L K++ I + N+ N+
Sbjct: 2072 LADSVAKTNAVVKDPSKNKIIADADATVKNLEQEADRLIDKLKPIKEL---EDNLKKNIS 2128
Query: 2372 RIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKG-YTSLSLFLQRPNSRENGG 2430
I+ELI QAR A+ + V + SG + E KG Y ++ + ++
Sbjct: 2129 EIKELINQARKQANSIKVSV----SSGGDCIRTYKPEIKKGSYNNIVVNVKT-------A 2177
Query: 2431 TENMFVMYLGNKDASRDYIGMAVVDGQLTCVYNLGDREAELQV-DQILTKSETKEAVMDR 2489
+ + YLG+ D++ + + G+++ ++++G ++ D + S V R
Sbjct: 2178 VADNLLFYLGSAKFI-DFLAIEMRKGKVSFLWDVGSGVGRVEYPDLTIDDSYWYRIVASR 2236
Query: 2490 VKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKL 2549
L+ K + P + T+L++D N + +VGG K
Sbjct: 2237 TGRNGTISVRALDGPKASI-----VPSTHHSTSPPGYTILDVD-ANAMLFVGGLTGKLKK 2290
Query: 2550 PSRLSFPPYKGCIELDDLNENVLSLYNFK-KTFNLNTTEVEPCRRRKEESDKN-YFEGTG 2607
+ + GC+ + + L+NF+ K + V P + E+S+ F+G G
Sbjct: 2291 ADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSP---QVEDSEGTIQFDGEG 2347
Query: 2608 YARV--PTQPHAPIPTFGQTIQTTVDRGLLFFAENGD--RFISLNIEDGKLMVRYKLNSE 2663
YA V P + + I T +T LL + D F+S+ + DG + V Y L S
Sbjct: 2348 YALVSRPIRWYPNISTVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHIKVSYDLGS- 2406
Query: 2664 LPKERGVGDAINNGRDHSIQIK---IGKLQKRMWIN-VDVQN-------TIIDGEVFDF- 2711
G+ ++N + + K + ++QK+ I+ VD+ T G F
Sbjct: 2407 -----GMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNFGLD 2461
Query: 2712 ----STYYLGGIPIAIRERFNISTPAFRGCMKNL---KKTSGVVRLNDTVGVTKKCSEDW 2764
Y GG+P R ++ + GC+K++ + ++ D VGVTK CS
Sbjct: 2462 LKADDKIYFGGLPTLRNLRPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVTKGCS--L 2519
Query: 2765 KLVRSASFSRGGQLSFTDLGLPPTD-HLQASFGFQTFQPSGILL-------------DHQ 2810
+ V + SF + G F +L P D + + F T SGI+L Q
Sbjct: 2520 ENVYTVSFPKPG---FVELSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKRRQ 2576
Query: 2811 TWTRNLQVTLEDGYIELSTSDSGSPIFK-----SPQTYMDGLLHYVSVISDNSGLRLLID 2865
T + L G +E+ S + K P + DG H V V + +D
Sbjct: 2577 TGQAYYVILLNRGRLEVHLSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQVD 2636
Query: 2866 DQLLRNSKRLKHISSSR----QSLRLGGS-------------NFEGCISNVFVQRLSLSP 2908
+ N + +++++ + + L +GG+ FEGCI N+ + +
Sbjct: 2637 E----NRRYMQNLTVEQPIEVKKLFVGGAPPEFQPSPLRNIPPFEGCIWNLVINSVP--- 2689
Query: 2909 EVLDLTSNSLKRDVSLGGCSLNKPPFLMLLKGSTRFNKTKTFRINQLLQDTPVASPR--- 2965
+D ++ +G C+ K R ++ ++Q PV +P
Sbjct: 2690 --MDFARPVSFKNADIGRCAHQK----------LREDEDGAAPAEIVIQPEPVPTPAFPT 2737
Query: 2966 -SVKVWQDACSPLPKTQANHGALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGL 3024
+ + C+ + G+ QFG SH+ +K R ++++T + GL
Sbjct: 2738 PTPVLTHGPCAAESEPALLIGSKQFGLSRNSHIAIAFDDTKVKNRLTIELEVRTEAESGL 2797
Query: 3025 VFHTGTKN--SFMALYLSKGRLVFALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRL 3082
+F+ N F + L G F+ K NDG+WH + ++G L
Sbjct: 2798 LFYMARINHADFATVQLRNGLPYFSYDLGSGDTHTMIPTKINDGQWHKIKIMRSKQEGIL 2857
Query: 3083 VVDGLRAREGSLPGNSTISIRAPVYLGSPP---SGKPKSLPTNSFVGCLKNFQLDSKP-- 3137
VDG R S + + +Y+G P + + T S GC++N + P
Sbjct: 2858 YVDGASNRTISPKKADILDVVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPAD 2917
Query: 3138 LYTPSSSFGVSSCLGGPLEKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIH 3197
L P+SSF V +C ++G YF + G +G + + F R + TG+L+
Sbjct: 2918 LEQPTSSFHVGTCFAN-AQRGTYF-DGTGFAKAVGGFKVGLDLLVEFEFRTTTTTGVLLG 2975
Query: 3198 IGSQPGKHLCVYLEAGKVTASMDSGAGGTST--SVTPKQSLCDGQWHSVAVTIKQHILHL 3255
I SQ + + + K+ +D+GAG + LCDGQWH V +H +
Sbjct: 2976 ISSQKMDGMGIEMIDEKLMFHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKH--RI 3033
Query: 3256 ELDTDSSYTAGQIPFP---PASTQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNH-- 3310
EL D + Q P P A T +P+ +GG P +L + F GC+R++ +
Sbjct: 3034 ELTVDGNQVEAQSPNPASTSADTNDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGT 3093
Query: 3311 ---IPVPVTEALEVQG--PVSLNGCP 3331
+ V +ALE++G PVS CP
Sbjct: 3094 GKPLEVNFAKALELRGVQPVS---CP 3116
Score = 451 bits (1160), Expect = e-126
Identities = 234/525 (44%), Positives = 304/525 (57%), Gaps = 66/525 (12%)
Query: 47 LHPTYFNLAEAARIWATATCGERGPGEGRPQPELYCKLVGGPTAPGSGHTIQGQFCDYCN 106
L P NLA A I ATCGE+GP E+YCKLV G ++ C CN
Sbjct: 39 LFPAVLNLASNALITTNATCGEKGP-------EMYCKLVEHVP----GQPVRNPQCRICN 87
Query: 107 --SEDPRKAHPVTNAIDGSERWWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKFANSP 164
S +P + HP+TNAIDG WWQSP + +G +Y+ V +TLDL Q+F +AY+++K ANSP
Sbjct: 88 QNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANSP 147
Query: 165 RPDLWVLERSVDFGSTYSPWQYFAHSKVDCLKEFG---REANMAVTRDDDVLCVTEYSRI 221
RP W+LERS+D Y PWQY A + +CL + R + +DD+V+C + YS+I
Sbjct: 148 RPGNWILERSLD-DVEYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTSFYSKI 206
Query: 222 VPLENGEVVVSLINGRPGAKNFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDPT 281
PLENGE+ +SLINGRP A + S L EFT A IRLRF R TL L+ A +DP
Sbjct: 207 HPLENGEIHISLINGRPSADDP--SPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPR 264
Query: 282 -----VTRRYYYSIKDISIGGQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTG 336
VTRRYYYS+KDIS+GG C+C GHA C ++ RCEC+H+TCG++CD+CC G
Sbjct: 265 EIDPIVTRRYYYSVKDISVGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPG 324
Query: 337 YNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHN 396
++Q+ WR + ECEACNCHG A CYYD +V R+ SLN +G Y GGGVCINC N
Sbjct: 325 FHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQN 384
Query: 397 TAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDP------------EHA-DGCEQGSGRC 443
TAG+NCE C G++RP GV + P C PC CDP +HA G GS C
Sbjct: 385 TAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGS--C 442
Query: 444 HCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEIC 503
HCK F G +C++CA GY +P C K C+C+ G E
Sbjct: 443 HCKTGFGGVSCDRCARGYTGYPDC---------------------KACNCSGLGSKNE-D 480
Query: 504 DAHGRCLCRPGVEGPRCDTCRSGFY-----SFPICQACWCSALGS 543
G C+C+ VEG C C+SGF+ ++ C C+CS + +
Sbjct: 481 PCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSGVSN 525
Score = 333 bits (855), Expect = 1e-90
Identities = 207/608 (34%), Positives = 292/608 (48%), Gaps = 81/608 (13%)
Query: 1284 QCPCQPNVIGRQCTRCATGHYGFP----------RCKPCSCG--------------RRLC 1319
+C C+ N G C +C G + P C+ C+C R L
Sbjct: 306 RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLS 365
Query: 1320 EEMTGQ-------CRCPPRTVRPQCEVCETHSFSFHPMA-------GCEGCNCSRRGTIE 1365
+ G+ C T CE C T F F P C+ C+C G++
Sbjct: 366 LNIRGKYIGGGVCINCTQNTAGINCETC-TDGF-FRPKGVSPNYPRPCQPCHCDPIGSLN 423
Query: 1366 AAMPECDRDS------GQCRCKPRITGRQCDRCASGFYRFPECVPCNCNRDGTEPGVCDP 1419
+ ++ + G C CK G CDRCA G+ +P+C CNC+ G++ DP
Sbjct: 424 EVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNE--DP 481
Query: 1420 GTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFCFGVNNQCHSSHKRRTKFVDML 1479
G C+CKENVEG +C+ C+ G F+L N KGC CFC GV+N+C SS+ K DM
Sbjct: 482 CFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDMS 541
Query: 1480 GWHLETADRVDIP--VSFNPGSNSM-------VADLQELPATIHSASWVAPTSYLGDKVS 1530
GW+L D+P + P + + +++ + A HS W AP YLG+K+
Sbjct: 542 GWYL-----TDLPGRIRVAPQQDDLDSPQQISISNAEARQALPHSYYWSAPAPYLGNKLP 596
Query: 1531 SYGGYLTYQAKSFGLPGDMVLLEKKPDVQ--LTGQHMSIIYEETNTP-RPDRLHHGRVHV 1587
+ GG LT+ S+ L + E+ + L G +SI + P H + +
Sbjct: 597 AVGGQLTFTI-SYDLEEEEEDTERVLQLMIILEGNDLSISTAQDEVYLHPSEEHTNVLLL 655
Query: 1588 VEGNFRHASSRAPVSREELMTVLSRLADVRIQGLY-FTETQRLTLSEVGLEEA-SDTGSG 1645
E +F + PV R+E MTVL+ L V +Q Y F LS V LE A S G
Sbjct: 656 KEESFTIHGTHFPVRRKEFMTVLANLKRVLLQITYSFGMDAIFRLSSVNLESAVSYPTDG 715
Query: 1646 RIALAVEICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVN 1705
IA AVE+C CPP Y G SC+ C P + R + ++ G C PC C GH+ C D +G C+N
Sbjct: 716 SIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLN 775
Query: 1706 CQHNTAGEHCERCQEGYYGNAVHGS---CRACPCP---HTNSFATGCVVNG--GDVRCSC 1757
C+ +T G +C++C G+YG G+ C+ C CP +N+F+ C ++ G + C
Sbjct: 776 CKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGC 835
Query: 1758 KAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQL---GSCHPLTGDCINQEPKDSS 1814
GYTG +CERCA GYFG P GGSCQPC CN N GSC L+G C+ +P +
Sbjct: 836 PVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKP--GT 893
Query: 1815 PAEECDDC 1822
C+ C
Sbjct: 894 TGRYCELC 901
Score = 204 bits (518), Expect = 2e-51
Identities = 134/440 (30%), Positives = 190/440 (43%), Gaps = 71/440 (16%)
Query: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 358
C C GHAE C+ E L C+ HT G CD+C G+ + S +C+ C C
Sbjct: 757 CQCFGHAESCDDVTGECL---NCKDHTGGPYCDKCLPGFYGEPTKGT----SEDCQPCAC 809
Query: 359 HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVD 418
+ + + P ++ G +C C G CE+CA+GY+ VP
Sbjct: 810 PLNIPSNNFSPTCHLDRSL---------GLICDGCPVGYTGPRCERCAEGYFGQPSVPGG 860
Query: 419 APDGCIPCSC----DPEHADGCEQGSGRCH-CKPNFHGDNCEKCAIGYYNFPFCLRIPIF 473
+ C PC C D C+ SG C CKP G CE CA GY+
Sbjct: 861 S---CQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFG---------- 907
Query: 474 PVSTPSSEDPV-AGDIKGCDCNLEGVLPEICDAH-GRCLCRPGVEGPRCDTCRSGFYSFP 531
D V A + + C CN G E+C + G+C CR V+G RCD C++G +
Sbjct: 908 --------DAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQ 959
Query: 532 I---CQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDP 588
C C C++ GS C +GQC C+PGVTG++CDRC G ++F +G +AC+
Sbjct: 960 SARGCVPCNCNSFGSKSFDCEE-SGQCWCQPGVTGKKCDRCAHGYFNFQ--EGGCTACEC 1016
Query: 589 AGTINS---NLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGEC 645
+ N+ G C C + G CS+C W +GC C C G++ +C
Sbjct: 1017 SHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWG--HSITTGCKACNCSTVGSLDF--QC 1072
Query: 646 RQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSS---------MC 696
G C+C G C C G++ NY C C C + G ++ C
Sbjct: 1073 NVNTGQCNCHPKFSGAKCTECSRGHW-----NYPRCNLCDCFLPGTDATTCDSETKKCSC 1127
Query: 697 SGPSGVCQCREHVVGKVCQR 716
S +G C C+ +V G C R
Sbjct: 1128 SDQTGQCTCKVNVEGIHCDR 1147
Score = 190 bits (482), Expect = 2e-47
Identities = 127/420 (30%), Positives = 172/420 (40%), Gaps = 77/420 (18%)
Query: 319 CECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASL 378
C+C G +C+ C R R CE C C GHA +C DV
Sbjct: 724 CQCPPGYTGSSCESCWP----RHRRVNGTIFGGICEPCQCFGHAESC---DDVT------ 770
Query: 379 NTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAP-DGCIPCSCDPEHADGCE 437
G C+NC+ +T G C++C G+Y G P + C PC+C
Sbjct: 771 ---------GECLNCKDHTGGPYCDKCLPGFY---GEPTKGTSEDCQPCACPLNIPSN-- 816
Query: 438 QGSGRCH-----------CKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAG 486
S CH C + G CE+CA GY+ P S P G
Sbjct: 817 NFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQP----------SVPG------G 860
Query: 487 DIKGCDCN--LEGVLPEICDA-HGRCL-CRPGVEGPRCDTCRSGFYSFPI----CQACWC 538
+ C CN L+ +P CD+ G CL C+PG G C+ C G++ + CQ C C
Sbjct: 861 SCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRC 920
Query: 539 SALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSA-CDPAGTIN---S 594
+A GS+ C S TGQCECR V GQRCD+C +G + +G C+ G+ +
Sbjct: 921 NAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCE 980
Query: 595 NLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHC 654
G C C+ V G C RC Y+N + GC+ C+C G C G C C
Sbjct: 981 ESGQCWCQPGVTGKKCDRCAHGYFNFQE---GGCTACECSHLG-----NNCDPKTGRCIC 1032
Query: 655 KSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVC 714
+ G+ C C + S GC+ C C G+L C+ +G C C G C
Sbjct: 1033 PPNTIGEKCSKCAPNTWG--HSITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKC 1090
Score = 137 bits (344), Expect = 2e-31
Identities = 81/253 (32%), Positives = 111/253 (43%), Gaps = 59/253 (23%)
Query: 1264 LPCECHPTGATGPHC-----------SPEGGQC-PCQ----------------------- 1288
L C+ P G TGP C S GG C PCQ
Sbjct: 830 LICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLIC 889
Query: 1289 -PNVIGRQCTRCATGHYG----FPRCKPCSCG-----RRLCEEMTGQCRCPPRTVRPQCE 1338
P GR C CA G++G C+PC C +C TGQC C +C+
Sbjct: 890 KPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCD 949
Query: 1339 VCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYR 1398
C+ +F GC CNC+ G+ +C+ +SGQC C+P +TG++CDRCA G++
Sbjct: 950 KCKAGTFGLQSARGCVPCNCNSFGSKSF---DCE-ESGQCWCQPGVTGKKCDRCAHGYFN 1005
Query: 1399 FPE--CVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSC 1456
F E C C C+ G CDP TG C+C N G +C+ C ++ + GC +C
Sbjct: 1006 FQEGGCTACECSHLGNN---CDPKTGRCICPPNTIGEKCSKCAPNTW--GHSITTGCKAC 1060
Query: 1457 FCFGVNN---QCH 1466
C V + QC+
Sbjct: 1061 NCSTVGSLDFQCN 1073
Score = 127 bits (318), Expect = 2e-28
Identities = 91/310 (29%), Positives = 121/310 (39%), Gaps = 59/310 (19%)
Query: 443 CHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEI 502
C C P + G +CE C +P + G + C C G
Sbjct: 724 CQCPPGYTGSSCESC---------------WPRHRRVNGTIFGGICEPCQCF--GHAESC 766
Query: 503 CDAHGRCL-CRPGVEGPRCDTCRSGFYSFPI------CQACWCSALGSYQMPCSSVTGQC 555
D G CL C+ GP CD C GFY P CQ C C +P ++ + C
Sbjct: 767 DDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPL----NIPSNNFSPTC 822
Query: 556 E-----------CRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPA-----------GTIN 593
C G TG RC+RC G + P G S C P G+ +
Sbjct: 823 HLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGS--CQPCQCNDNLDFSIPGSCD 880
Query: 594 SNLGYCQ-CKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDC 652
S G C CK G C C Y+ D + C C+C+ G+ S C G C
Sbjct: 881 SLSGSCLICKPGTTGRYCELCADGYFG-DAVDAKNCQPCRCNAGGSFSEV--CHSQTGQC 937
Query: 653 HCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGK 712
C+++V G CD C+ G F L+ + GC C C+ G+ S C SG C C+ V GK
Sbjct: 938 ECRANVQGQRCDKCKAGTFGLQSAR--GCVPCNCNSFGSKSFDCE-ESGQCWCQPGVTGK 994
Query: 713 VCQRPENNYY 722
C R + Y+
Sbjct: 995 KCDRCAHGYF 1004
Score = 117 bits (292), Expect = 2e-25
Identities = 71/221 (32%), Positives = 99/221 (44%), Gaps = 34/221 (15%)
Query: 1265 PCECHPTGATGPHCSPEGGQC-PCQPNVIGRQCTRCATGHYGFPR------CKPCSCGRR 1317
PC+C + C G+C C+ + G C +C G YG P C+PC+C
Sbjct: 756 PCQCFGHAES---CDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLN 812
Query: 1318 L-CEEMTGQCR-----------CPPRTVRPQCEVCETHSFSFHPMAG--CEGCNCSRRGT 1363
+ + C CP P+CE C F + G C+ C C+
Sbjct: 813 IPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCN--DN 870
Query: 1364 IEAAMP-ECDRDSGQCR-CKPRITGRQCDRCASGFYR----FPECVPCNCNRDGTEPGVC 1417
++ ++P CD SG C CKP TGR C+ CA G++ C PC CN G+ VC
Sbjct: 871 LDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVC 930
Query: 1418 DPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFC 1458
TG C C+ NV+G C+ C+ G+F L A +GC C C
Sbjct: 931 HSQTGQCECRANVQGQRCDKCKAGTFGLQSA--RGCVPCNC 969
Score = 110 bits (274), Expect = 3e-23
Identities = 61/177 (34%), Positives = 85/177 (48%), Gaps = 15/177 (8%)
Query: 1653 IC-ACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSN-----QCQDGSGICVNC 1706
IC CP Y G C+ C+ GY+ + G C PC CN + + C SG C+ C
Sbjct: 831 ICDGCPVGYTGPRCERCAEGYF-GQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLIC 889
Query: 1707 QHNTAGEHCERCQEGYYGNAVHG-SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQ 1765
+ T G +CE C +GY+G+AV +C+ C C SF+ C G +C C+A G +
Sbjct: 890 KPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTG--QCECRANVQGQR 947
Query: 1766 CERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 1822
C++C G FG G C PC+CNS G +G C Q ++CD C
Sbjct: 948 CDKCKAGTFGLQSARG--CVPCNCNSFGSKSFDCEESGQCWCQ---PGVTGKKCDRC 999
Score = 108 bits (271), Expect = 7e-23
Identities = 64/194 (32%), Positives = 90/194 (46%), Gaps = 30/194 (15%)
Query: 392 NCQHNTAGVNCEQCAKGYYRPYGVPVDAPDG-----CIPCSCDPEHADGCEQGSGRC-HC 445
+C +G++CE C G+YR P G C+PC C+ H+ C+ + C +C
Sbjct: 1381 DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNG-HSSLCDPETSICQNC 1439
Query: 446 KPNFHGDNCEKCAIGYYNFPF-----CLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLP 500
+ + GD CE+CA+GYY C + +S+ ++ P C EG+
Sbjct: 1440 QHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSP--------SCVAEGLDD 1491
Query: 501 EICDAHGRCLCRPGVEGPRCDTCRSGFYSFP-----ICQACWCSALGSYQMPCSSVTGQC 555
C A C G EG C+ C G+ P CQ C C GS +PC VTG C
Sbjct: 1492 YRCTA-----CPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFC 1546
Query: 556 ECRPGVTGQRCDRC 569
CRPG TG++CD C
Sbjct: 1547 TCRPGATGRKCDGC 1560
Score = 107 bits (268), Expect = 2e-22
Identities = 72/233 (30%), Positives = 98/233 (42%), Gaps = 35/233 (15%)
Query: 432 HADGCE----QGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGD 487
HA C RC C+ N GD+C++C G++ P+ R F T G
Sbjct: 292 HARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPW--RAGTFLTKTECEACNCHGK 349
Query: 488 IKGCDC-------NLEGVLPEICDAHGRCL-CRPGVEGPRCDTCRSGFY-------SFPI 532
+ C NL + G C+ C G C+TC GF+ ++P
Sbjct: 350 AEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPR 409
Query: 533 -CQACWCSALGSYQMPCSS---------VTGQCECRPGVTGQRCDRCLSGAYDFPHCQGS 582
CQ C C +GS C G C C+ G G CDRC G +P C+
Sbjct: 410 PCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKAC 469
Query: 583 SSACDPAGTINSN--LGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKC 633
+ C G+ N + G C CK +VEG CSRCK ++NL ++N GC EC C
Sbjct: 470 N--CSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFC 520
Score = 104 bits (259), Expect = 2e-21
Identities = 69/220 (31%), Positives = 94/220 (42%), Gaps = 50/220 (22%)
Query: 318 RCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHE---CEACNCHGHASNCYYDPDVERQ 374
+C+C G +C+ C G+ + R +P C C C+GH+S C DP+
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLC--DPETS-- 1434
Query: 375 QASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSC-----D 429
+C NCQH+TAG CE+CA GY YG+ P+ C C+C
Sbjct: 1435 --------------ICQNCQHHTAGDFCERCALGY---YGIVKGLPNDCQQCACPLISSS 1477
Query: 430 PEHADGCEQ---GSGRC-HCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVA 485
+ C RC C + G CE+CA GY T S +P
Sbjct: 1478 NNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGY---------------TGSPGNP-G 1521
Query: 486 GDIKGCDCNLEGVLPEICD-AHGRCLCRPGVEGPRCDTCR 524
G + C+C+ G LP CD G C CRPG G +CD C+
Sbjct: 1522 GSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGCK 1561
Score = 101 bits (252), Expect = 1e-20
Identities = 73/245 (29%), Positives = 98/245 (40%), Gaps = 57/245 (23%)
Query: 308 CNINN-PEKLFRCE------CQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHG 360
CN N+ K F CE CQ G+ CDRC GY Q C AC C
Sbjct: 967 CNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFN--------FQEGGCTACECSH 1018
Query: 361 HASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAP 420
+NC DP G CI C NT G C +CA +G +
Sbjct: 1019 LGNNC--DPKT----------------GRCI-CPPNTIGEKCSKCAP---NTWGHSITT- 1055
Query: 421 DGCIPCSCDPEHA--DGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTP 478
GC C+C + C +G+C+C P F G C +C+ G++N+P C F T
Sbjct: 1056 -GCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTD 1114
Query: 479 SSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPI-----C 533
++ + K C C+ D G+C C+ VEG CD CR G + C
Sbjct: 1115 AT--TCDSETKKCSCS---------DQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGC 1163
Query: 534 QACWC 538
+C+C
Sbjct: 1164 SSCYC 1168
Score = 90.9 bits (224), Expect = 2e-17
Identities = 55/196 (28%), Positives = 78/196 (39%), Gaps = 28/196 (14%)
Query: 542 GSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFP------------------HCQGSS 583
G+ P + + +C+C G +G C+ CL G Y C G S
Sbjct: 1367 GTTMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHS 1426
Query: 584 SACDPAGTINSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTG 643
S CDP +I N C+ H G C RC L Y+ + K P+ C +C C + +
Sbjct: 1427 SLCDPETSICQN-----CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFS 1481
Query: 644 ECRQGDG--DCHCKS---HVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSG 698
+G D C + G C+ C GY + CQ C+CD G+L C
Sbjct: 1482 PSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDP 1541
Query: 699 PSGVCQCREHVVGKVC 714
+G C CR G+ C
Sbjct: 1542 VTGFCTCRPGATGRKC 1557
Score = 81.3 bits (199), Expect = 2e-14
Identities = 50/161 (31%), Positives = 70/161 (43%), Gaps = 22/161 (13%)
Query: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 358
C CNGH+ +C+ PE CQHHT G+ C+RC GY ++C+ C C
Sbjct: 1420 CQCNGHSSLCD---PETSICQNCQHHTAGDFCERCALGY-----YGIVKGLPNDCQQCAC 1471
Query: 359 HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVD 418
+S+ + P S +G+ C C G CE+CA GY G P +
Sbjct: 1472 PLISSSNNFSP-------SCVAEGL--DDYRCTACPRGYEGQYCERCAPGY---TGSPGN 1519
Query: 419 APDGCIPCSCDPEHA--DGCEQGSGRCHCKPNFHGDNCEKC 457
C C CDP + C+ +G C C+P G C+ C
Sbjct: 1520 PGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGC 1560
Score = 63.2 bits (152), Expect = 4e-09
Identities = 34/115 (29%), Positives = 47/115 (40%), Gaps = 14/115 (12%)
Query: 1259 YHKGALPCECHPTGATGPHCSPEG---------GQCPCQPNVIGRQCTRCATGHYGFPRC 1309
Y + PC C P G+ C + G C C+ G C RCA G+ G+P C
Sbjct: 407 YPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDC 466
Query: 1310 KPCSC---GRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHP--MAGCEGCNCS 1359
K C+C G + + G C C C C++ F+ GC+ C CS
Sbjct: 467 KACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCS 521
Score = 60.1 bits (144), Expect = 4e-08
Identities = 52/191 (27%), Positives = 66/191 (34%), Gaps = 39/191 (20%)
Query: 508 RCLCRPGVEGPRCDTCRSGFY-------------SFPICQACWCSALGSYQMPCSSVTGQ 554
+C C G G C+ C GFY + C C C+ S C T
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL---CDPETSI 1435
Query: 555 CE-CRPGVTGQRCDRCLSGAYDF-----PHCQGSSSACDPAGTINSNLGYC--------- 599
C+ C+ G C+RC G Y CQ AC + N+ C
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQ--QCACPLISSSNNFSPSCVAEGLDDYR 1493
Query: 600 --QCKLHVEGPTCSRCKLLYWNLDKENPSG-CSECKCHKAGTVSGTGECRQGDGDCHCKS 656
C EG C RC Y NP G C EC+C G++ C G C C+
Sbjct: 1494 CTACPRGYEGQYCERCAPGYTG-SPGNPGGSCQECECDPYGSL--PVPCDPVTGFCTCRP 1550
Query: 657 HVGGDSCDTCE 667
G CD C+
Sbjct: 1551 GATGRKCDGCK 1561
Score = 50.4 bits (119), Expect = 3e-05
Identities = 39/150 (26%), Positives = 55/150 (36%), Gaps = 29/150 (19%)
Query: 590 GTINSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSG-CSECKC--HKAGTVSGTGECR 646
G+I + + CQC G +C C + ++ G C C+C H TGEC
Sbjct: 715 GSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGEC- 773
Query: 647 QGDGDCHCKSHVGGDSCDTCEDGYFA-LEKSNYFGCQGCQCDIG-------------GAL 692
+CK H GG CD C G++ K CQ C C + +L
Sbjct: 774 -----LNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSL 828
Query: 693 SSMCSGPSGVCQCREHVVGKVCQRPENNYY 722
+C G C G C+R Y+
Sbjct: 829 GLICDG------CPVGYTGPRCERCAEGYF 852
Score = 48.5 bits (114), Expect = 1e-04
Identities = 33/133 (24%), Positives = 47/133 (35%), Gaps = 29/133 (21%)
Query: 1355 GCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFP----------ECVP 1404
G C G A + + +C C+ G CD+C GF++ P EC
Sbjct: 284 GGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEA 343
Query: 1405 CNCNRDGTEPGVCDP---------------GTGACL-CKENVEGTECNVCREGSFH---L 1445
CNC+ E + G G C+ C +N G C C +G F +
Sbjct: 344 CNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGV 403
Query: 1446 DPANLKGCTSCFC 1458
P + C C C
Sbjct: 404 SPNYPRPCQPCHC 416
Score = 43.9 bits (102), Expect = 0.003
Identities = 24/80 (30%), Positives = 33/80 (41%), Gaps = 12/80 (15%)
Query: 652 CHCKSHVGGDSCDTCEDGYFALEKS--------NYFGCQGCQCDIGGALSSMCSGPSGVC 703
C C G SC+ C G++ L C CQC+ SS+C + +C
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCN---GHSSLCDPETSIC 1436
Query: 704 Q-CREHVVGKVCQRPENNYY 722
Q C+ H G C+R YY
Sbjct: 1437 QNCQHHTAGDFCERCALGYY 1456
Score = 37.0 bits (84), Expect = 0.33
Identities = 16/60 (26%), Positives = 27/60 (45%)
Query: 1268 CHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCGRRLCEEMTGQCR 1327
C+ +G + P G C C+ NV G C+RC +G + C C ++ +C+
Sbjct: 469 CNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSGVSNRCQ 528
>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
sapiens]
Length = 3122
Score = 644 bits (1661), Expect = 0.0
Identities = 591/2250 (26%), Positives = 964/2250 (42%), Gaps = 270/2250 (12%)
Query: 1261 KGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPR--CKPCSCGR-- 1316
+G +PC C+ G+ C E GQC CQP V G++C RCA G++ F C C C
Sbjct: 962 RGCVPCNCNSFGSKSFDCE-ESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLG 1020
Query: 1317 RLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSG 1376
C+ TG+C CPP T+ +C C +++ GC+ CNCS G+++ +C+ ++G
Sbjct: 1021 NNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDF---QCNVNTG 1077
Query: 1377 QCRCKPRITGRQCDRCASGFYRFPECVPCNCNRDGTEPGVCDPGT---------GACLCK 1427
QC C P+ +G +C C+ G + +P C C+C GT+ CD T G C CK
Sbjct: 1078 QCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCK 1137
Query: 1428 ENVEGTECNVCREGSFHLDPANLKGCTSCFCFGVNNQCHSSHKRRTKFVDMLGWHLETAD 1487
NVEG C+ CR G F LD N GC+SC+CFG QC + +V + A+
Sbjct: 1138 VNVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTWVTL------KAE 1191
Query: 1488 RVDIPVSFNPGSNS-----------MVADLQELPATIHSAS--WVAPTSYLGDKVSSYGG 1534
+ +P+ ++ +VA + + +H W P + G K+ +YGG
Sbjct: 1192 QTILPLVDEALQHTTTKGIVFQHPEIVAHMDLMREDLHLEPFYWKLPEQFEGKKLMAYGG 1251
Query: 1535 YLTYQAKSFGLPGDMVLLEKKPDVQLTG---QHMSIIYEETNTPRPDRLHHGRVHVVEGN 1591
L Y A F + P V + G H II P +L + + E
Sbjct: 1252 KLKY-AIYFEAREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTRHEIEMTEKE 1310
Query: 1592 FRHASS----RAPVSREELMTVLSRLADVRIQGLYFTETQRLTLSEVGLEEASDTGSGRI 1647
+++ V+RE+ + +L + + I+ Y ++ +SE+ +E A + G G
Sbjct: 1311 WKYYGDDPRVHRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEVA-EQGRGTT 1369
Query: 1648 ----ALAVEICACPPAYAGDSCQGCSPGYYRDHK-------GLYTGRCVPCNCNGHSNQC 1696
A +E C CP Y+G SC+ C PG+YR G G CVPC CNGHS+ C
Sbjct: 1370 MTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLC 1429
Query: 1697 QDGSGICVNCQHNTAGEHCERCQEGYYG--NAVHGSCRACPCP---HTNSFATGCVVNG- 1750
+ IC NCQH+TAG+ CERC GYYG + C+ C CP +N+F+ CV G
Sbjct: 1430 DPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGL 1489
Query: 1751 GDVRC-SCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLG-SCHPLTGDCINQ 1808
D RC +C GY G CERCAPGY G+P GGSCQ C C+ G L C P+TG C
Sbjct: 1490 DDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFC--- 1546
Query: 1809 EPKDSSPAEECDDC---------------DSCVMTLLNDLATMGEQLRLVKSQLQGLSAS 1853
+ + +CD C D C LL DLA + EQ+ + + L A
Sbjct: 1547 TCRPGATGRKCDGCKHWHAREGWECVFCGDECTGLLLGDLARL-EQMVMSINLTGPLPAP 1605
Query: 1854 AGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEG-LERELTDLNQEFETLQEKAQVN 1912
+L + +M + K LL+ + A EG L +T++N E L +V
Sbjct: 1606 YKMLYGLENMTQELK----HLLSPQRAPERLIQLAEGNLNTLVTEMN---ELLTRATKVT 1658
Query: 1913 SRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHILLK---QISGTDGEGNNVPSGDFSRE 1969
+ QT + R AK L IK + R+ + + +++ T G + +
Sbjct: 1659 ADGEQT-GQDAERTNTRAKSLGEFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGL 1717
Query: 1970 WAEAQRMMRELRNRNFGKHLREAEADKRESQLLLNRIRTWQKTHQGENNGLANSIRDSLN 2029
E +M++ELR +N AE + ++ LL +++ +GEN + +R+ L
Sbjct: 1718 QKEIDQMIKELRRKNLETQKEIAEDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLA 1777
Query: 2030 EYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLTTADS 2089
+Y+ K+ D L+EA + ++AN L N++ + A++++ + + S + L +
Sbjct: 1778 DYKNKVDDAWDLLREATDKIREANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGND 1837
Query: 2090 SLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVE---EAEKHA 2146
L + N + E + L +EL+DK+ +LS+ L E +AE HA
Sbjct: 1838 ILDEANRLADEINSIIDYVEDIQTKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHA 1897
Query: 2147 RSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESA--L 2204
L + + L+ I A + A A AY NI + I AE A A + A L
Sbjct: 1898 AQLNDSSAVLDGILDEAK--NISFNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKL 1955
Query: 2205 QTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDT 2264
T + L AK S ++LNEAK +K E LN L+ + + +
Sbjct: 1956 ATGPRGLLKEDAKGCLQKSFRILNEAKKLANDVK-ENEDHLNGLKTRIENADARNGDL-- 2012
Query: 2265 NLTTLRDGLHGIQR--GDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGR 2322
L TL D L + D A + + K R+AND +VL + + +++ +K Y +
Sbjct: 2013 -LRTLNDTLGKLSAIPNDTAAKLQAVKDKARQANDTAKDVLAQITELHQNLDGLKKNYNK 2071
Query: 2323 TQNEDFK-----------KALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNMD 2371
+ K K + DAD +V L + L K++ I + N+ N+
Sbjct: 2072 LADSVAKTNAVVKDPSKNKIIADADATVKNLEQEADRLIDKLKPIKEL---EDNLKKNIS 2128
Query: 2372 RIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKG-YTSLSLFLQRPNSRENGG 2430
I+ELI QAR A+ + V + SG + E KG Y ++ + ++
Sbjct: 2129 EIKELINQARKQANSIKVSV----SSGGDCIRTYKPEIKKGSYNNIVVNVKT-------A 2177
Query: 2431 TENMFVMYLGNKDASRDYIGMAVVDGQLTCVYNLGDREAELQV-DQILTKSETKEAVMDR 2489
+ + YLG+ D++ + + G+++ ++++G ++ D + S V R
Sbjct: 2178 VADNLLFYLGSAKFI-DFLAIEMRKGKVSFLWDVGSGVGRVEYPDLTIDDSYWYRIVASR 2236
Query: 2490 VKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKL 2549
L+ K + P + T+L++D N + +VGG K
Sbjct: 2237 TGRNGTISVRALDGPKASI-----VPSTHHSTSPPGYTILDVD-ANAMLFVGGLTGKLKK 2290
Query: 2550 PSRLSFPPYKGCIELDDLNENVLSLYNFK-KTFNLNTTEVEPCRRRKEESDKN-YFEGTG 2607
+ + GC+ + + L+NF+ K + V P + E+S+ F+G G
Sbjct: 2291 ADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSP---QVEDSEGTIQFDGEG 2347
Query: 2608 YARV--PTQPHAPIPTFGQTIQTTVDRGLLFFAENGD--RFISLNIEDGKLMVRYKLNSE 2663
YA V P + + I T +T LL + D F+S+ + DG + V Y L S
Sbjct: 2348 YALVSRPIRWYPNISTVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHIKVSYDLGS- 2406
Query: 2664 LPKERGVGDAINNGRDHSIQIK---IGKLQKRMWIN-VDVQN-------TIIDGEVFDF- 2711
G+ ++N + + K + ++QK+ I+ VD+ T G F
Sbjct: 2407 -----GMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNFGLD 2461
Query: 2712 ----STYYLGGIP----IAIRERFNISTPAFRGCMKNL---KKTSGVVRLNDTVGVTKKC 2760
Y GG+P ++++ R ++ + GC+K++ + ++ D VGVTK C
Sbjct: 2462 LKADDKIYFGGLPTLRNLSMKARPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVTKGC 2521
Query: 2761 SEDWKLVRSASFSRGGQLSFTDLGLPPTD-HLQASFGFQTFQPSGILL------------ 2807
S + V + SF + G F +L P D + + F T SGI+L
Sbjct: 2522 S--LENVYTVSFPKPG---FVELSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRR 2576
Query: 2808 -DHQTWTRNLQVTLEDGYIELSTSDSGSPIFK-----SPQTYMDGLLHYVSVISDNSGLR 2861
QT + L G +E+ S + K P + DG H V V
Sbjct: 2577 KRRQTGQAYYVILLNRGRLEVHLSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFT 2636
Query: 2862 LLIDDQLLRNSKRLKHISSSR----QSLRLGGS-------------NFEGCISNVFVQRL 2904
+ +D+ N + +++++ + + L +GG+ FEGCI N+ + +
Sbjct: 2637 VQVDE----NRRYMQNLTVEQPIEVKKLFVGGAPPEFQPSPLRNIPPFEGCIWNLVINSV 2692
Query: 2905 SLSPEVLDLTSNSLKRDVSLGGCSLNKPPFLMLLKGSTRFNKTKTFRINQLLQDTPVASP 2964
+D ++ +G C+ K R ++ ++Q PV +P
Sbjct: 2693 P-----MDFARPVSFKNADIGRCAHQK----------LREDEDGAAPAEIVIQPEPVPTP 2737
Query: 2965 R----SVKVWQDACSPLPKTQANHGALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTS 3020
+ + C+ + G+ QFG SH+ +K R ++++T +
Sbjct: 2738 AFPTPTPVLTHGPCAAESEPALLIGSKQFGLSRNSHIAIAFDDTKVKNRLTIELEVRTEA 2797
Query: 3021 SRGLVFHTGTKN--SFMALYLSKGRLVFALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGE 3078
GL+F+ N F + L G F+ K NDG+WH + +
Sbjct: 2798 ESGLLFYMARINHADFATVQLRNGLPYFSYDLGSGDTHTMIPTKINDGQWHKIKIMRSKQ 2857
Query: 3079 KGRLVVDGLRAREGSLPGNSTISIRAPVYLGSPP---SGKPKSLPTNSFVGCLKNFQLDS 3135
+G L VDG R S + + +Y+G P + + T S GC++N +
Sbjct: 2858 EGILYVDGASNRTISPKKADILDVVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAE 2917
Query: 3136 KP--LYTPSSSFGVSSCLGGPLEKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTG 3193
P L P+SSF V +C ++G YF + G +G + + F R + TG
Sbjct: 2918 APADLEQPTSSFHVGTCFAN-AQRGTYF-DGTGFAKAVGGFKVGLDLLVEFEFRTTTTTG 2975
Query: 3194 ILIHIGSQPGKHLCVYLEAGKVTASMDSGAGGTST--SVTPKQSLCDGQWHSVAVTIKQH 3251
+L+ I SQ + + + K+ +D+GAG + LCDGQWH V +H
Sbjct: 2976 VLLGISSQKMDGMGIEMIDEKLMFHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKH 3035
Query: 3252 ILHLELDTDSSYTAGQIPFP---PASTQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHV 3308
+EL D + Q P P A T +P+ +GG P +L + F GC+R++ +
Sbjct: 3036 --RIELTVDGNQVEAQSPNPASTSADTNDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKL 3093
Query: 3309 NH-----IPVPVTEALEVQG--PVSLNGCP 3331
+ V +ALE++G PVS CP
Sbjct: 3094 TKGTGKPLEVNFAKALELRGVQPVS---CP 3120
Score = 451 bits (1160), Expect = e-126
Identities = 234/525 (44%), Positives = 304/525 (57%), Gaps = 66/525 (12%)
Query: 47 LHPTYFNLAEAARIWATATCGERGPGEGRPQPELYCKLVGGPTAPGSGHTIQGQFCDYCN 106
L P NLA A I ATCGE+GP E+YCKLV G ++ C CN
Sbjct: 39 LFPAVLNLASNALITTNATCGEKGP-------EMYCKLVEHVP----GQPVRNPQCRICN 87
Query: 107 --SEDPRKAHPVTNAIDGSERWWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKFANSP 164
S +P + HP+TNAIDG WWQSP + +G +Y+ V +TLDL Q+F +AY+++K ANSP
Sbjct: 88 QNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANSP 147
Query: 165 RPDLWVLERSVDFGSTYSPWQYFAHSKVDCLKEFG---REANMAVTRDDDVLCVTEYSRI 221
RP W+LERS+D Y PWQY A + +CL + R + +DD+V+C + YS+I
Sbjct: 148 RPGNWILERSLD-DVEYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTSFYSKI 206
Query: 222 VPLENGEVVVSLINGRPGAKNFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDPT 281
PLENGE+ +SLINGRP A + S L EFT A IRLRF R TL L+ A +DP
Sbjct: 207 HPLENGEIHISLINGRPSADDP--SPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPR 264
Query: 282 -----VTRRYYYSIKDISIGGQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTG 336
VTRRYYYS+KDIS+GG C+C GHA C ++ RCEC+H+TCG++CD+CC G
Sbjct: 265 EIDPIVTRRYYYSVKDISVGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPG 324
Query: 337 YNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHN 396
++Q+ WR + ECEACNCHG A CYYD +V R+ SLN +G Y GGGVCINC N
Sbjct: 325 FHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQN 384
Query: 397 TAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDP------------EHA-DGCEQGSGRC 443
TAG+NCE C G++RP GV + P C PC CDP +HA G GS C
Sbjct: 385 TAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGS--C 442
Query: 444 HCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEIC 503
HCK F G +C++CA GY +P C K C+C+ G E
Sbjct: 443 HCKTGFGGVSCDRCARGYTGYPDC---------------------KACNCSGLGSKNE-D 480
Query: 504 DAHGRCLCRPGVEGPRCDTCRSGFY-----SFPICQACWCSALGS 543
G C+C+ VEG C C+SGF+ ++ C C+CS + +
Sbjct: 481 PCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSGVSN 525
Score = 333 bits (855), Expect = 1e-90
Identities = 207/608 (34%), Positives = 292/608 (48%), Gaps = 81/608 (13%)
Query: 1284 QCPCQPNVIGRQCTRCATGHYGFP----------RCKPCSCG--------------RRLC 1319
+C C+ N G C +C G + P C+ C+C R L
Sbjct: 306 RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLS 365
Query: 1320 EEMTGQ-------CRCPPRTVRPQCEVCETHSFSFHPMA-------GCEGCNCSRRGTIE 1365
+ G+ C T CE C T F F P C+ C+C G++
Sbjct: 366 LNIRGKYIGGGVCINCTQNTAGINCETC-TDGF-FRPKGVSPNYPRPCQPCHCDPIGSLN 423
Query: 1366 AAMPECDRDS------GQCRCKPRITGRQCDRCASGFYRFPECVPCNCNRDGTEPGVCDP 1419
+ ++ + G C CK G CDRCA G+ +P+C CNC+ G++ DP
Sbjct: 424 EVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNE--DP 481
Query: 1420 GTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFCFGVNNQCHSSHKRRTKFVDML 1479
G C+CKENVEG +C+ C+ G F+L N KGC CFC GV+N+C SS+ K DM
Sbjct: 482 CFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDMS 541
Query: 1480 GWHLETADRVDIP--VSFNPGSNSM-------VADLQELPATIHSASWVAPTSYLGDKVS 1530
GW+L D+P + P + + +++ + A HS W AP YLG+K+
Sbjct: 542 GWYL-----TDLPGRIRVAPQQDDLDSPQQISISNAEARQALPHSYYWSAPAPYLGNKLP 596
Query: 1531 SYGGYLTYQAKSFGLPGDMVLLEKKPDVQ--LTGQHMSIIYEETNTP-RPDRLHHGRVHV 1587
+ GG LT+ S+ L + E+ + L G +SI + P H + +
Sbjct: 597 AVGGQLTFTI-SYDLEEEEEDTERVLQLMIILEGNDLSISTAQDEVYLHPSEEHTNVLLL 655
Query: 1588 VEGNFRHASSRAPVSREELMTVLSRLADVRIQGLY-FTETQRLTLSEVGLEEA-SDTGSG 1645
E +F + PV R+E MTVL+ L V +Q Y F LS V LE A S G
Sbjct: 656 KEESFTIHGTHFPVRRKEFMTVLANLKRVLLQITYSFGMDAIFRLSSVNLESAVSYPTDG 715
Query: 1646 RIALAVEICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVN 1705
IA AVE+C CPP Y G SC+ C P + R + ++ G C PC C GH+ C D +G C+N
Sbjct: 716 SIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLN 775
Query: 1706 CQHNTAGEHCERCQEGYYGNAVHGS---CRACPCP---HTNSFATGCVVNG--GDVRCSC 1757
C+ +T G +C++C G+YG G+ C+ C CP +N+F+ C ++ G + C
Sbjct: 776 CKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGC 835
Query: 1758 KAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQL---GSCHPLTGDCINQEPKDSS 1814
GYTG +CERCA GYFG P GGSCQPC CN N GSC L+G C+ +P +
Sbjct: 836 PVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKP--GT 893
Query: 1815 PAEECDDC 1822
C+ C
Sbjct: 894 TGRYCELC 901
Score = 204 bits (518), Expect = 2e-51
Identities = 134/440 (30%), Positives = 190/440 (43%), Gaps = 71/440 (16%)
Query: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 358
C C GHAE C+ E L C+ HT G CD+C G+ + S +C+ C C
Sbjct: 757 CQCFGHAESCDDVTGECL---NCKDHTGGPYCDKCLPGFYGEPTKGT----SEDCQPCAC 809
Query: 359 HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVD 418
+ + + P ++ G +C C G CE+CA+GY+ VP
Sbjct: 810 PLNIPSNNFSPTCHLDRSL---------GLICDGCPVGYTGPRCERCAEGYFGQPSVPGG 860
Query: 419 APDGCIPCSC----DPEHADGCEQGSGRCH-CKPNFHGDNCEKCAIGYYNFPFCLRIPIF 473
+ C PC C D C+ SG C CKP G CE CA GY+
Sbjct: 861 S---CQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFG---------- 907
Query: 474 PVSTPSSEDPV-AGDIKGCDCNLEGVLPEICDAH-GRCLCRPGVEGPRCDTCRSGFYSFP 531
D V A + + C CN G E+C + G+C CR V+G RCD C++G +
Sbjct: 908 --------DAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQ 959
Query: 532 I---CQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDP 588
C C C++ GS C +GQC C+PGVTG++CDRC G ++F +G +AC+
Sbjct: 960 SARGCVPCNCNSFGSKSFDCEE-SGQCWCQPGVTGKKCDRCAHGYFNFQ--EGGCTACEC 1016
Query: 589 AGTINS---NLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGEC 645
+ N+ G C C + G CS+C W +GC C C G++ +C
Sbjct: 1017 SHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWG--HSITTGCKACNCSTVGSLDF--QC 1072
Query: 646 RQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSS---------MC 696
G C+C G C C G++ NY C C C + G ++ C
Sbjct: 1073 NVNTGQCNCHPKFSGAKCTECSRGHW-----NYPRCNLCDCFLPGTDATTCDSETKKCSC 1127
Query: 697 SGPSGVCQCREHVVGKVCQR 716
S +G C C+ +V G C R
Sbjct: 1128 SDQTGQCTCKVNVEGIHCDR 1147
Score = 190 bits (482), Expect = 2e-47
Identities = 127/420 (30%), Positives = 172/420 (40%), Gaps = 77/420 (18%)
Query: 319 CECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASL 378
C+C G +C+ C R R CE C C GHA +C DV
Sbjct: 724 CQCPPGYTGSSCESCWP----RHRRVNGTIFGGICEPCQCFGHAESC---DDVT------ 770
Query: 379 NTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAP-DGCIPCSCDPEHADGCE 437
G C+NC+ +T G C++C G+Y G P + C PC+C
Sbjct: 771 ---------GECLNCKDHTGGPYCDKCLPGFY---GEPTKGTSEDCQPCACPLNIPSN-- 816
Query: 438 QGSGRCH-----------CKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAG 486
S CH C + G CE+CA GY+ P S P G
Sbjct: 817 NFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQP----------SVPG------G 860
Query: 487 DIKGCDCN--LEGVLPEICDA-HGRCL-CRPGVEGPRCDTCRSGFYSFPI----CQACWC 538
+ C CN L+ +P CD+ G CL C+PG G C+ C G++ + CQ C C
Sbjct: 861 SCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRC 920
Query: 539 SALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSA-CDPAGTIN---S 594
+A GS+ C S TGQCECR V GQRCD+C +G + +G C+ G+ +
Sbjct: 921 NAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCE 980
Query: 595 NLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHC 654
G C C+ V G C RC Y+N + GC+ C+C G C G C C
Sbjct: 981 ESGQCWCQPGVTGKKCDRCAHGYFNFQE---GGCTACECSHLG-----NNCDPKTGRCIC 1032
Query: 655 KSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVC 714
+ G+ C C + S GC+ C C G+L C+ +G C C G C
Sbjct: 1033 PPNTIGEKCSKCAPNTWG--HSITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKC 1090
Score = 137 bits (344), Expect = 2e-31
Identities = 81/253 (32%), Positives = 111/253 (43%), Gaps = 59/253 (23%)
Query: 1264 LPCECHPTGATGPHC-----------SPEGGQC-PCQ----------------------- 1288
L C+ P G TGP C S GG C PCQ
Sbjct: 830 LICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLIC 889
Query: 1289 -PNVIGRQCTRCATGHYG----FPRCKPCSCG-----RRLCEEMTGQCRCPPRTVRPQCE 1338
P GR C CA G++G C+PC C +C TGQC C +C+
Sbjct: 890 KPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCD 949
Query: 1339 VCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYR 1398
C+ +F GC CNC+ G+ +C+ +SGQC C+P +TG++CDRCA G++
Sbjct: 950 KCKAGTFGLQSARGCVPCNCNSFGSKSF---DCE-ESGQCWCQPGVTGKKCDRCAHGYFN 1005
Query: 1399 FPE--CVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSC 1456
F E C C C+ G CDP TG C+C N G +C+ C ++ + GC +C
Sbjct: 1006 FQEGGCTACECSHLGNN---CDPKTGRCICPPNTIGEKCSKCAPNTW--GHSITTGCKAC 1060
Query: 1457 FCFGVNN---QCH 1466
C V + QC+
Sbjct: 1061 NCSTVGSLDFQCN 1073
Score = 127 bits (318), Expect = 2e-28
Identities = 91/310 (29%), Positives = 121/310 (39%), Gaps = 59/310 (19%)
Query: 443 CHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEI 502
C C P + G +CE C +P + G + C C G
Sbjct: 724 CQCPPGYTGSSCESC---------------WPRHRRVNGTIFGGICEPCQCF--GHAESC 766
Query: 503 CDAHGRCL-CRPGVEGPRCDTCRSGFYSFPI------CQACWCSALGSYQMPCSSVTGQC 555
D G CL C+ GP CD C GFY P CQ C C +P ++ + C
Sbjct: 767 DDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPL----NIPSNNFSPTC 822
Query: 556 E-----------CRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPA-----------GTIN 593
C G TG RC+RC G + P G S C P G+ +
Sbjct: 823 HLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGS--CQPCQCNDNLDFSIPGSCD 880
Query: 594 SNLGYCQ-CKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDC 652
S G C CK G C C Y+ D + C C+C+ G+ S C G C
Sbjct: 881 SLSGSCLICKPGTTGRYCELCADGYFG-DAVDAKNCQPCRCNAGGSFSEV--CHSQTGQC 937
Query: 653 HCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGK 712
C+++V G CD C+ G F L+ + GC C C+ G+ S C SG C C+ V GK
Sbjct: 938 ECRANVQGQRCDKCKAGTFGLQSAR--GCVPCNCNSFGSKSFDCE-ESGQCWCQPGVTGK 994
Query: 713 VCQRPENNYY 722
C R + Y+
Sbjct: 995 KCDRCAHGYF 1004
Score = 117 bits (292), Expect = 2e-25
Identities = 71/221 (32%), Positives = 99/221 (44%), Gaps = 34/221 (15%)
Query: 1265 PCECHPTGATGPHCSPEGGQC-PCQPNVIGRQCTRCATGHYGFPR------CKPCSCGRR 1317
PC+C + C G+C C+ + G C +C G YG P C+PC+C
Sbjct: 756 PCQCFGHAES---CDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLN 812
Query: 1318 L-CEEMTGQCR-----------CPPRTVRPQCEVCETHSFSFHPMAG--CEGCNCSRRGT 1363
+ + C CP P+CE C F + G C+ C C+
Sbjct: 813 IPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCN--DN 870
Query: 1364 IEAAMP-ECDRDSGQCR-CKPRITGRQCDRCASGFYR----FPECVPCNCNRDGTEPGVC 1417
++ ++P CD SG C CKP TGR C+ CA G++ C PC CN G+ VC
Sbjct: 871 LDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVC 930
Query: 1418 DPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFC 1458
TG C C+ NV+G C+ C+ G+F L A +GC C C
Sbjct: 931 HSQTGQCECRANVQGQRCDKCKAGTFGLQSA--RGCVPCNC 969
Score = 110 bits (274), Expect = 3e-23
Identities = 61/177 (34%), Positives = 85/177 (48%), Gaps = 15/177 (8%)
Query: 1653 IC-ACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSN-----QCQDGSGICVNC 1706
IC CP Y G C+ C+ GY+ + G C PC CN + + C SG C+ C
Sbjct: 831 ICDGCPVGYTGPRCERCAEGYF-GQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLIC 889
Query: 1707 QHNTAGEHCERCQEGYYGNAVHG-SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQ 1765
+ T G +CE C +GY+G+AV +C+ C C SF+ C G +C C+A G +
Sbjct: 890 KPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTG--QCECRANVQGQR 947
Query: 1766 CERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 1822
C++C G FG G C PC+CNS G +G C Q ++CD C
Sbjct: 948 CDKCKAGTFGLQSARG--CVPCNCNSFGSKSFDCEESGQCWCQ---PGVTGKKCDRC 999
Score = 108 bits (271), Expect = 7e-23
Identities = 64/194 (32%), Positives = 90/194 (46%), Gaps = 30/194 (15%)
Query: 392 NCQHNTAGVNCEQCAKGYYRPYGVPVDAPDG-----CIPCSCDPEHADGCEQGSGRC-HC 445
+C +G++CE C G+YR P G C+PC C+ H+ C+ + C +C
Sbjct: 1381 DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNG-HSSLCDPETSICQNC 1439
Query: 446 KPNFHGDNCEKCAIGYYNFPF-----CLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLP 500
+ + GD CE+CA+GYY C + +S+ ++ P C EG+
Sbjct: 1440 QHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSP--------SCVAEGLDD 1491
Query: 501 EICDAHGRCLCRPGVEGPRCDTCRSGFYSFP-----ICQACWCSALGSYQMPCSSVTGQC 555
C A C G EG C+ C G+ P CQ C C GS +PC VTG C
Sbjct: 1492 YRCTA-----CPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFC 1546
Query: 556 ECRPGVTGQRCDRC 569
CRPG TG++CD C
Sbjct: 1547 TCRPGATGRKCDGC 1560
Score = 107 bits (268), Expect = 2e-22
Identities = 72/233 (30%), Positives = 98/233 (42%), Gaps = 35/233 (15%)
Query: 432 HADGCE----QGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGD 487
HA C RC C+ N GD+C++C G++ P+ R F T G
Sbjct: 292 HARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPW--RAGTFLTKTECEACNCHGK 349
Query: 488 IKGCDC-------NLEGVLPEICDAHGRCL-CRPGVEGPRCDTCRSGFY-------SFPI 532
+ C NL + G C+ C G C+TC GF+ ++P
Sbjct: 350 AEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPR 409
Query: 533 -CQACWCSALGSYQMPCSS---------VTGQCECRPGVTGQRCDRCLSGAYDFPHCQGS 582
CQ C C +GS C G C C+ G G CDRC G +P C+
Sbjct: 410 PCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKAC 469
Query: 583 SSACDPAGTINSN--LGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKC 633
+ C G+ N + G C CK +VEG CSRCK ++NL ++N GC EC C
Sbjct: 470 N--CSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFC 520
Score = 104 bits (259), Expect = 2e-21
Identities = 69/220 (31%), Positives = 94/220 (42%), Gaps = 50/220 (22%)
Query: 318 RCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHE---CEACNCHGHASNCYYDPDVERQ 374
+C+C G +C+ C G+ + R +P C C C+GH+S C DP+
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLC--DPETS-- 1434
Query: 375 QASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSC-----D 429
+C NCQH+TAG CE+CA GY YG+ P+ C C+C
Sbjct: 1435 --------------ICQNCQHHTAGDFCERCALGY---YGIVKGLPNDCQQCACPLISSS 1477
Query: 430 PEHADGCEQ---GSGRC-HCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVA 485
+ C RC C + G CE+CA GY T S +P
Sbjct: 1478 NNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGY---------------TGSPGNP-G 1521
Query: 486 GDIKGCDCNLEGVLPEICD-AHGRCLCRPGVEGPRCDTCR 524
G + C+C+ G LP CD G C CRPG G +CD C+
Sbjct: 1522 GSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGCK 1561
Score = 101 bits (252), Expect = 1e-20
Identities = 73/245 (29%), Positives = 98/245 (40%), Gaps = 57/245 (23%)
Query: 308 CNINN-PEKLFRCE------CQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHG 360
CN N+ K F CE CQ G+ CDRC GY Q C AC C
Sbjct: 967 CNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFN--------FQEGGCTACECSH 1018
Query: 361 HASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAP 420
+NC DP G CI C NT G C +CA +G +
Sbjct: 1019 LGNNC--DPKT----------------GRCI-CPPNTIGEKCSKCAP---NTWGHSITT- 1055
Query: 421 DGCIPCSCDPEHA--DGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTP 478
GC C+C + C +G+C+C P F G C +C+ G++N+P C F T
Sbjct: 1056 -GCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTD 1114
Query: 479 SSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPI-----C 533
++ + K C C+ D G+C C+ VEG CD CR G + C
Sbjct: 1115 AT--TCDSETKKCSCS---------DQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGC 1163
Query: 534 QACWC 538
+C+C
Sbjct: 1164 SSCYC 1168
Score = 90.9 bits (224), Expect = 2e-17
Identities = 55/196 (28%), Positives = 78/196 (39%), Gaps = 28/196 (14%)
Query: 542 GSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFP------------------HCQGSS 583
G+ P + + +C+C G +G C+ CL G Y C G S
Sbjct: 1367 GTTMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHS 1426
Query: 584 SACDPAGTINSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTG 643
S CDP +I N C+ H G C RC L Y+ + K P+ C +C C + +
Sbjct: 1427 SLCDPETSICQN-----CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFS 1481
Query: 644 ECRQGDG--DCHCKS---HVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSG 698
+G D C + G C+ C GY + CQ C+CD G+L C
Sbjct: 1482 PSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDP 1541
Query: 699 PSGVCQCREHVVGKVC 714
+G C CR G+ C
Sbjct: 1542 VTGFCTCRPGATGRKC 1557
Score = 81.3 bits (199), Expect = 2e-14
Identities = 50/161 (31%), Positives = 70/161 (43%), Gaps = 22/161 (13%)
Query: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 358
C CNGH+ +C+ PE CQHHT G+ C+RC GY ++C+ C C
Sbjct: 1420 CQCNGHSSLCD---PETSICQNCQHHTAGDFCERCALGY-----YGIVKGLPNDCQQCAC 1471
Query: 359 HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVD 418
+S+ + P S +G+ C C G CE+CA GY G P +
Sbjct: 1472 PLISSSNNFSP-------SCVAEGL--DDYRCTACPRGYEGQYCERCAPGY---TGSPGN 1519
Query: 419 APDGCIPCSCDPEHA--DGCEQGSGRCHCKPNFHGDNCEKC 457
C C CDP + C+ +G C C+P G C+ C
Sbjct: 1520 PGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGC 1560
Score = 63.2 bits (152), Expect = 4e-09
Identities = 34/115 (29%), Positives = 47/115 (40%), Gaps = 14/115 (12%)
Query: 1259 YHKGALPCECHPTGATGPHCSPEG---------GQCPCQPNVIGRQCTRCATGHYGFPRC 1309
Y + PC C P G+ C + G C C+ G C RCA G+ G+P C
Sbjct: 407 YPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDC 466
Query: 1310 KPCSC---GRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHP--MAGCEGCNCS 1359
K C+C G + + G C C C C++ F+ GC+ C CS
Sbjct: 467 KACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCS 521
Score = 60.1 bits (144), Expect = 4e-08
Identities = 52/191 (27%), Positives = 66/191 (34%), Gaps = 39/191 (20%)
Query: 508 RCLCRPGVEGPRCDTCRSGFY-------------SFPICQACWCSALGSYQMPCSSVTGQ 554
+C C G G C+ C GFY + C C C+ S C T
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL---CDPETSI 1435
Query: 555 CE-CRPGVTGQRCDRCLSGAYDF-----PHCQGSSSACDPAGTINSNLGYC--------- 599
C+ C+ G C+RC G Y CQ AC + N+ C
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQ--QCACPLISSSNNFSPSCVAEGLDDYR 1493
Query: 600 --QCKLHVEGPTCSRCKLLYWNLDKENPSG-CSECKCHKAGTVSGTGECRQGDGDCHCKS 656
C EG C RC Y NP G C EC+C G++ C G C C+
Sbjct: 1494 CTACPRGYEGQYCERCAPGYTG-SPGNPGGSCQECECDPYGSL--PVPCDPVTGFCTCRP 1550
Query: 657 HVGGDSCDTCE 667
G CD C+
Sbjct: 1551 GATGRKCDGCK 1561
Score = 50.4 bits (119), Expect = 3e-05
Identities = 39/150 (26%), Positives = 55/150 (36%), Gaps = 29/150 (19%)
Query: 590 GTINSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSG-CSECKC--HKAGTVSGTGECR 646
G+I + + CQC G +C C + ++ G C C+C H TGEC
Sbjct: 715 GSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGEC- 773
Query: 647 QGDGDCHCKSHVGGDSCDTCEDGYFA-LEKSNYFGCQGCQCDIG-------------GAL 692
+CK H GG CD C G++ K CQ C C + +L
Sbjct: 774 -----LNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSL 828
Query: 693 SSMCSGPSGVCQCREHVVGKVCQRPENNYY 722
+C G C G C+R Y+
Sbjct: 829 GLICDG------CPVGYTGPRCERCAEGYF 852
Score = 48.5 bits (114), Expect = 1e-04
Identities = 33/133 (24%), Positives = 47/133 (35%), Gaps = 29/133 (21%)
Query: 1355 GCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFP----------ECVP 1404
G C G A + + +C C+ G CD+C GF++ P EC
Sbjct: 284 GGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEA 343
Query: 1405 CNCNRDGTEPGVCDP---------------GTGACL-CKENVEGTECNVCREGSFH---L 1445
CNC+ E + G G C+ C +N G C C +G F +
Sbjct: 344 CNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGV 403
Query: 1446 DPANLKGCTSCFC 1458
P + C C C
Sbjct: 404 SPNYPRPCQPCHC 416
Score = 43.9 bits (102), Expect = 0.003
Identities = 24/80 (30%), Positives = 33/80 (41%), Gaps = 12/80 (15%)
Query: 652 CHCKSHVGGDSCDTCEDGYFALEKS--------NYFGCQGCQCDIGGALSSMCSGPSGVC 703
C C G SC+ C G++ L C CQC+ SS+C + +C
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCN---GHSSLCDPETSIC 1436
Query: 704 Q-CREHVVGKVCQRPENNYY 722
Q C+ H G C+R YY
Sbjct: 1437 QNCQHHTAGDFCERCALGYY 1456
Score = 37.0 bits (84), Expect = 0.33
Identities = 16/60 (26%), Positives = 27/60 (45%)
Query: 1268 CHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCGRRLCEEMTGQCR 1327
C+ +G + P G C C+ NV G C+RC +G + C C ++ +C+
Sbjct: 469 CNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSGVSNRCQ 528
>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
Length = 3075
Score = 631 bits (1627), Expect = e-180
Identities = 588/2236 (26%), Positives = 956/2236 (42%), Gaps = 277/2236 (12%)
Query: 1262 GALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFP--RCKPCSCG--RR 1317
G PC C G+ C+ EG QC C P V G++C RCA G Y + C PC C +
Sbjct: 947 GCRPCNCSVAGSVSDGCTDEG-QCHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDCPHTQN 1005
Query: 1318 LCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQ 1377
C+ TG+C CPP T +CE CE + + GC+ CNCS G+ CD +G
Sbjct: 1006 TCDPETGECVCPPHTQGVKCEECEDGHWGYDAEVGCQACNCSLVGSTHH---RCDVVTGH 1062
Query: 1378 CRCKPRITGRQCDRCASGFYRFPECVPCNCNRDGT-------EPGVCD--PGTGACLCKE 1428
C+CK + GR CD+C+ G+ FP+CVPC+C+ GT E G+C TGAC CKE
Sbjct: 1063 CQCKSKFGGRACDQCSLGYRDFPDCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKE 1122
Query: 1429 NVEGTECNVCREGSFHLDPANLKGCTSCFCFGVNNQCHSSHKRRTKFVDMLGWHLETADR 1488
NV G +CN CREG+F L N GC+ CFC G+++ C E D
Sbjct: 1123 NVFGPQCNECREGTFALRADNPLGCSPCFCSGLSHLCS-----------------ELEDY 1165
Query: 1489 VDIPVSFNPGSNSM-VADLQELPATIHSAS-----------------------WVAPTSY 1524
V PV+ + V L T W P +
Sbjct: 1166 VRTPVTLGSDQPLLRVVSQSNLRGTTEGVYYQAPDFLLDAATVRQHIRAEPFYWRLPQQF 1225
Query: 1525 LGDKVSSYGGYLTYQAKSFGLPGDMVLLEKKPDVQLTGQHM--SIIYEETNTPRPDRLHH 1582
GD++ +YGG L Y + L G + +P V + G + +IY + P
Sbjct: 1226 QGDQLMAYGGKLKYSVAFYSLDG-VGTSNFEPQVLIKGGRIRKQVIYMDAPAPENGVRQE 1284
Query: 1583 GRVHVVEGNFRHASS--RAPVSREELMTVLSRLADVRIQGLYFTETQRLTLSEVGLEEAS 1640
V + E +++ +S PV+RE+ M+VLS + + I+ Y Q+ +S++ +E
Sbjct: 1285 QEVAMRENFWKYFNSVSEKPVTREDFMSVLSDIEYILIKASYGQGLQQSRISDISMEVGR 1344
Query: 1641 DTGS----GRIALAVEICACPPAYAGDSCQGCSPGYYRDHKGLYTGR--------CVPCN 1688
+A +E C CPP G SCQ C+PGY+R + R CVPC+
Sbjct: 1345 KAEKLHPEEEVASLLENCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCS 1404
Query: 1689 CNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGS--CRACPCPHTN--SFAT 1744
CN HS+ C +G C+NC NTAG+HC+ C GYYG + C C CPH+ SF+
Sbjct: 1405 CNNHSDTCDPNTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSP 1464
Query: 1745 GCVVNGG-DVRC-SCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQL-GSCHPL 1801
CV+ G D RC +C GY G CERC+ Y+GNPQ GGSCQ C CN +G + G C
Sbjct: 1465 TCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRT 1524
Query: 1802 TGDCINQEPKDSSPAEECD--------DC----DSCVMTLLNDLATMGEQLRLVKSQLQG 1849
+G C+ + +EC+ DC D CV LLNDL +G+ + + L G
Sbjct: 1525 SGQCVCRLGASGLRCDECEPRHILMETDCVSCDDECVGVLLNDLDEIGDAV--LSLNLTG 1582
Query: 1850 L-SASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFETLQEK 1908
+ G+L ++E K L+ LL K+EG+ +E + LQ+K
Sbjct: 1583 IIPVPYGILS---NLENTTKYLQESLLKENMQKDLGKIKLEGVA-------EETDNLQKK 1632
Query: 1909 AQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHILLKQ--ISGTDGEGNNVPSGDF 1966
Q +N R + +++L + I+ + ++ ++++ ++ T E +P+
Sbjct: 1633 LTRMLASTQKVNRATERIFKESQDLAIAIERLQMSITEIMEKTTLNQTLDEDFLLPNSTL 1692
Query: 1967 SREWAEAQRMMRELRNRNFGKHLREAEADKRESQLLLNRIRTWQKTHQGENNGLANSIRD 2026
++ ++ R+F + + A + + ++ LL++I+ + E L +
Sbjct: 1693 QNMQQNGTSLLEIMQIRDFTQLHQNATLELKAAEDLLSQIQENYQKPLEELEVLKEAASH 1752
Query: 2027 SLNEYEAKLSDLRARLQEAAAQAKQANGLN---QENERALGAIQRQVKEINSLQSDF-TK 2082
L+++ +L A ++EA A+ +++N L N R + V+E +L S+ +
Sbjct: 1753 VLSKHNNELKAAEALVREAEAKMQESNHLLLMVNANLREFSDKKLHVQEEQNLTSELIVQ 1812
Query: 2083 YLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEA 2142
D++ QT+ +E + +KL + R + D V +S+ LV A
Sbjct: 1813 GRGLIDAAAAQTDAVQDALEHLEDHQDKLLLWSAKIRHHIDDLVMHMSQR-NAVDLVYRA 1871
Query: 2143 EKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRA-ASASE 2201
E HA Q LA L N L A AA + NI + I+ +E+ A A + +E
Sbjct: 1872 EDHAAEFQRLADVLYSGLENIRNVSLN--ATSAAYVHYNIQSLIEESEELARDAHRTVTE 1929
Query: 2202 SALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLK------QEVSPALNNLQQTLNIV 2255
++L + E L K S + L E +KL E+ N Q+ +
Sbjct: 1930 TSL---LSESLVSNGKAAVQRSSRFLKEGNNLSRKLPGIALELSELRNKTNRFQENAVEI 1986
Query: 2256 TVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVER 2315
T Q L + G+ + S+++S V D+ + LN + R
Sbjct: 1987 TRQTNESLLILRAIPKGIRDKGAKTKELATSASQSAVSTLRDVAGLSQELLNT-SASLSR 2045
Query: 2316 IKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLG----NISDNMD 2371
+ T T + L D+ + K+ D+ + + +L PL N+S N+
Sbjct: 2046 VNTTLRETH-----QLLQDSTMATLLAGRKVKDVEIQANLLFDRLKPLKMLEENLSRNLS 2100
Query: 2372 RIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSRENGGT 2431
I+ LI QAR A+ + V + + + + P +L++ Q P++
Sbjct: 2101 EIKLLISQARKQAASIKVAVSAD-RDCIRAYQPQISSTNYNTLTLNVKTQEPDN------ 2153
Query: 2432 ENMFVMYLGNKDASRDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAV----M 2487
+ YLG+ AS D++ + + G++ +++LG L+ ++
Sbjct: 2154 ---LLFYLGSSTAS-DFLAVEMRRGRVAFLWDLGSGSTRLEFPDFPIDDNRWHSIHVARF 2209
Query: 2488 DRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDF 2547
+ + + + + TS P T V D+ N++TL+ +VGG
Sbjct: 2210 GNIGSLSVKEMSSNQKSPTKTSKSPGTANVLDV---NNSTLM---------FVGGLGGQI 2257
Query: 2548 KLPSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPCRRRKEESDKNY-FEGT 2606
K + +KGC+ LN + L+N+ + + C + D ++ F+G+
Sbjct: 2258 KKSPAVKVTHFKGCLGEAFLNGKSIGLWNYIE----REGKCRGCFGSSQNEDPSFHFDGS 2313
Query: 2607 GYARVPTQPHAPIPTFGQTIQTTVDRGLLFFAEN-GDR-FISLNIEDGKLMVRYKLNSEL 2664
GY+ V A + T GLL + + G + F+S+ + G++ V L S
Sbjct: 2314 GYSVVEKSLPATVTQIIMLFNTFSPNGLLLYLGSYGTKDFLSIELFRGRVKVMTDLGSG- 2372
Query: 2665 PKERGVGDAINNGRDHSIQIKIGKLQKRMWINVDVQNT----IIDGEV---------FDF 2711
P NNG + I + + Q + + +D NT GE D
Sbjct: 2373 PITLLTDRRYNNGTWYKIAFQRNRKQGVLAV-IDAYNTSNKETKQGETPGASSDLNRLDK 2431
Query: 2712 STYYLGGIPIAIRERFNISTPAFRGCMKNLK-KTSGVVRLNDTVGVTKKCSEDWKLVRSA 2770
Y+GG+P + R ++T +F GC+KNL+ S L ++ GV K C + +RS
Sbjct: 2432 DPIYVGGLPRSRVVRRGVTTKSFVGCIKNLEISRSTFDLLRNSYGVRKGCLLE--PIRSV 2489
Query: 2771 SFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGILLD------------HQTWTRNLQV 2818
SF +GG + L P +F T SGI+L + V
Sbjct: 2490 SFLKGGYIELPPKSLSPESEWLVTFA--TTNSSGIILAALGGDVEKRGDREEAHVPFFSV 2547
Query: 2819 TLEDGYIELSTSDS-GSPIFKS-----PQTYMDGLLHYVSVISDNSGLRLLIDDQLLRNS 2872
L G IE+ + G+ + K+ T DG H +S++ + R +I QL N+
Sbjct: 2548 MLIGGNIEVHVNPGDGTGLRKALLHAPTGTCSDGQAHSISLVRN----RRIITVQLDENN 2603
Query: 2873 K---RLKHISSSR----QSLRLGG-------------SNFEGCISNVFVQRLSLSPEVLD 2912
+L + SR +L +GG +F GCI N L + E+LD
Sbjct: 2604 PVEMKLGTLVESRTINVSNLYVGGIPEGEGTSLLTMRRSFHGCIKN-----LIFNLELLD 2658
Query: 2913 LTSNSLKRDVSLGGCSLNKPPFLMLLKGSTRFNKTKTFRINQLLQDTPVASPRSVKVWQD 2972
S V L C L++ P L ++LL + P A P V
Sbjct: 2659 FNSAVGHEQVDLDTCWLSERPKL-----------APDAEDSKLLPE-PRAFPEQCVV-DA 2705
Query: 2973 ACSPLPKTQANHGALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTGTKN 3032
A +P GA QFG SH + Q ++ + + ++T +S GL+++ +N
Sbjct: 2706 ALEYVP------GAHQFGLTQNSHFILPFNQSAVRKKLSVELSIRTFASSGLIYYMAHQN 2759
Query: 3033 S--FMALYLSKGRLVFALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAR 3090
+ L L GRL F + ++ +DGKWHTV + KG + VDG +
Sbjct: 2760 QADYAVLQLHGGRLHFMFDLGKGRTKVSHPALLSDGKWHTVKTDYVKRKGFITVDGRESP 2819
Query: 3091 EGSLPGNST-ISIRAPVYLGSPPS---GKPKSLPTNSFVGCLKNFQLDSKPL--YTPSSS 3144
++ G+ T + + YLG PS + T+S C+ + ++SK L +P S+
Sbjct: 2820 MVTVVGDGTMLDVEGLFYLGGLPSQYQARKIGNITHSIPACIGDVTVNSKQLDKDSPVSA 2879
Query: 3145 FGVSSCLGGPLEKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGK 3204
F V+ C ++G YF G ++ + + + R S G+L+ I +
Sbjct: 2880 FTVNRCY-AVAQEGTYFDGSGYAALVKEGYKVQSDVNITLEFRTSSQNGVLLGISTAKVD 2938
Query: 3205 HLCVYLEAGKVTASMDSGAGGTSTSVTPKQS--LCDGQWHSVAVTIKQHILHLELDTDSS 3262
+ + L GKV +++GAG + + PK + LCDG+WH++ +H + L D +
Sbjct: 2939 AIGLELVDGKVLFHVNNGAGRITAAYEPKTATVLCDGKWHTLQANKSKH--RITLIVDGN 2996
Query: 3263 YTAGQIPFPPAS---TQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIP----VPV 3315
+ P ++ T P+++GG PA + + SF GCLR + + P
Sbjct: 2997 AVGAESPHTQSTSVDTNNPIYVGGYPAGVKQKCLRSQTSFRGCLRKLALIKSPQVQSFDF 3056
Query: 3316 TEALEVQGPVSLNGCP 3331
+ A E+ G V L+ CP
Sbjct: 3057 SRAFELHG-VFLHSCP 3071
Score = 456 bits (1172), Expect = e-127
Identities = 242/566 (42%), Positives = 316/566 (55%), Gaps = 73/566 (12%)
Query: 25 VLRVLPAC-GATARDPGAAAGLSLHPTYFNLAEAARIWATATCGERGPGEGRPQPELYCK 83
VL VL C A R G L P NLA A I ATCGE+GP E++CK
Sbjct: 5 VLLVLLLCVAAQCRQRG------LFPAILNLASNAHISTNATCGEKGP-------EMFCK 51
Query: 84 LVGGPTAPGSGHTIQGQFCDYC--NSEDPRKAHPVTNAIDGSERWWQSPPLSSGTQYNRV 141
LV G ++ C C NS +PR+ HP+++AIDG+ WWQSP + +G +Y+ V
Sbjct: 52 LVEHVP----GRPVRNPQCRICDGNSANPRERHPISHAIDGTNNWWQSPSIQNGREYHWV 107
Query: 142 NLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVDFGSTYSPWQYFAHSKVDCLKEFG-- 199
+TLDL Q+F VAY++IK AN+PRP W+LERS+D G+T+SPWQY+A S +CL +
Sbjct: 108 TITLDLRQVFQVAYVIIKAANAPRPGNWILERSLD-GTTFSPWQYYAVSDSECLSRYNIT 166
Query: 200 -REANMAVTRDDDVLCVTEYSRIVPLENGEVVVSLINGRPGAKNFTFSHTLREFTKATNI 258
R DD+V+C + YSR+VPLE+GE+ SLINGRP A + S L EFT A I
Sbjct: 167 PRRGPPTYRADDEVICTSYYSRLVPLEHGEIHTSLINGRPSADDL--SPKLLEFTSARYI 224
Query: 259 RLRFLRTNTLLGHLISKAQR-----DPTVTRRYYYSIKDISIGGQCVCNGHAEVCNINNP 313
RLR R TL L++ + R DP VTRRYYYSIKDIS+GG C+C GHA C +
Sbjct: 225 RLRLQRIRTLNADLMTLSHREPKELDPIVTRRYYYSIKDISVGGMCICYGHASSCPWDET 284
Query: 314 EKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVER 373
K +C+C+H+TCGE+C+RCC GY+Q+ WRP + CEACNCH A +CYYD V +
Sbjct: 285 TKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAK 344
Query: 374 QQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPE-- 431
Q+ SLNT G + GGGVCINC NT G+NCE C GYYRP+ V + C PC+CDP
Sbjct: 345 QKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGS 404
Query: 432 ----------HADGCEQGS--GRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPS 479
H+D G G+C CK + G+ C++C +GY ++P C+ PV + S
Sbjct: 405 LSSVCIKDDLHSD-LHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCNPVGSAS 463
Query: 480 SEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPI-----CQ 534
E G C+C+ VEG CD C+ GFY+ C
Sbjct: 464 DE----------------------PCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCS 501
Query: 535 ACWCSALGSYQMPCSSVTGQCECRPG 560
C+C + S GQ G
Sbjct: 502 ECFCFGVSDVCSSLSWPVGQVNSMSG 527
Score = 330 bits (847), Expect = 1e-89
Identities = 204/606 (33%), Positives = 292/606 (48%), Gaps = 75/606 (12%)
Query: 1284 QCPCQPNVIGRQCTRCATGHYGFP----------RCKPCSCGRRLCE------------- 1320
QC C+ N G C RC G++ P C+ C+C + +
Sbjct: 289 QCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKS 348
Query: 1321 -EMTGQCR-------CPPRTVRPQCEVC-----ETHSFSFHPMAGCEGCNCSRRGTIEAA 1367
GQ R C T+ CE C H S + C CNC G++ +
Sbjct: 349 LNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSV 408
Query: 1368 MPECDRDS--------GQCRCKPRITGRQCDRCASGFYRFPECVPCNCNRDGTEPGVCDP 1419
+ D S GQC CK TG +CDRC G+ +P CV C CN G+ +P
Sbjct: 409 CIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCNPVGSASD--EP 466
Query: 1420 GTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFCFGVNNQCHSSHKRRTKFVDML 1479
TG C+CKENVEG C+ C+ G ++L N +GC+ CFCFGV++ C S + M
Sbjct: 467 CTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFCFGVSDVCSSLSWPVGQVNSMS 526
Query: 1480 GWHL-------ETADRVDIPVSFNPGSNSMVADLQELPATIHSASWVAPTSYLGDKVSSY 1532
GW + + + D + S + A +Q L + W AP +YLG+K++++
Sbjct: 527 GWLVTDLISPRKIPSQQDALGGRHQVSINNTAVMQRLAPKYY---WAAPEAYLGNKLTAF 583
Query: 1533 GGYLTYQAKSFGLPGDMV--LLEKKPDVQLTGQHMSIIYE-ETNTPRPDRLHHGRVHVVE 1589
GG+L Y S+ +P + V L DV + G +++ + E + +P + V +V
Sbjct: 584 GGFLKYTV-SYDIPVETVDSNLMSHADVIIKGNGLTLSTQAEGLSLQPYEEYLNVVRLVP 642
Query: 1590 GNFRHASSRAPVSREELMTVLSRLADVRIQGLYFTETQRL-TLSEVGLEEASDTGSGRIA 1648
NF+ S+ + R++LMTVL+ + + I+ Y + L L V L+ AS +
Sbjct: 643 ENFQDFHSKRQIDRDQLMTVLANVTHLLIRANYNSAKMALYRLESVSLDIASSNAIDLVV 702
Query: 1649 LA-VEICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQ 1707
A VE C CP Y G SC+ C GYYR L+ G C PC C+GH+ +C + G+C+ C
Sbjct: 703 AADVEHCECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAEC-NVHGVCIACA 761
Query: 1708 HNTAGEHCERCQEGYYG---NAVHGSCRACPCPHT---NSFATGCVVNGGD-VRCS-CKA 1759
HNT G HCE+C G+YG G C+ C CP T N+F+ C +N GD V C C
Sbjct: 762 HNTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAP 821
Query: 1760 GYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSN---GQLGSCHPLTGDCIN-QEPKDSSP 1815
GY+G CERCA GY+GNP G SC PC C+ N + G C +TG+C+ D +
Sbjct: 822 GYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAH 881
Query: 1816 AEECDD 1821
E C D
Sbjct: 882 CERCAD 887
Score = 227 bits (579), Expect = 1e-58
Identities = 142/454 (31%), Positives = 193/454 (42%), Gaps = 77/454 (16%)
Query: 287 YYSIKDISIGG---QCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGY--NQRR 341
YY + I GG C C+GHA CN++ C H+T G C++C G+ R
Sbjct: 727 YYRVDGILFGGICQPCECHGHAAECNVHG----VCIACAHNTTGVHCEQCLPGFYGEPSR 782
Query: 342 WRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVN 401
P +C+ C C ++ + P VC C +G
Sbjct: 783 GTPG------DCQPCACPLTIASNNFSPTCHLNDGD---------EVVCDWCAPGYSGAW 827
Query: 402 CEQCAKGYYRPYGVPVDAPDGCIPCSC----DPEHADGCEQGSGRC-HCKPNFHGDNCEK 456
CE+CA GYY G P + C+PC C DP A C+ +G C C N G +CE+
Sbjct: 828 CERCADGYY---GNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCER 884
Query: 457 CAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAH-GRCLCRPGV 515
CA G+Y + A + + C+C+++G +C G C C+P V
Sbjct: 885 CADGFYG-----------------DAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNV 927
Query: 516 EGPRCDTCRSGFYSFPI---CQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSG 572
G +CD C G+Y C+ C CS GS C+ GQC C PGV G+RCDRC G
Sbjct: 928 TGQQCDQCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTD-EGQCHCVPGVAGKRCDRCAHG 986
Query: 573 AYDFPHCQGSSSACDPAGTINS---NLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCS 629
Y + GS + CD T N+ G C C H +G C C+ +W D E GC
Sbjct: 987 FYAYQ--DGSCTPCDCPHTQNTCDPETGECVCPPHTQGVKCEECEDGHWGYDAE--VGCQ 1042
Query: 630 ECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIG 689
C C G+ C G C CKS GG +CD C GY ++ C C CD+
Sbjct: 1043 ACNCSLVGSTHH--RCDVVTGHCQCKSKFGGRACDQCSLGY-----RDFPDCVPCDCDLR 1095
Query: 690 GALSSMCS---------GPSGVCQCREHVVGKVC 714
G C+ +G C C+E+V G C
Sbjct: 1096 GTSGDACNLEQGLCGCVEETGACPCKENVFGPQC 1129
Score = 169 bits (428), Expect = 4e-41
Identities = 108/359 (30%), Positives = 154/359 (42%), Gaps = 79/359 (22%)
Query: 299 CVCNGHAEVCNINNPEKLF-RC-ECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEAC 356
C C+G+ + + + + C +C +T G C+RC G+ + A ++ C AC
Sbjct: 849 CDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCADGF----YGDAVTAKN--CRAC 902
Query: 357 NCH---GHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPY 413
CH H++ C+ + G+C +C+ N G C+QC GYY
Sbjct: 903 ECHVKGSHSAVCHLET------------------GLC-DCKPNVTGQQCDQCLHGYYG-- 941
Query: 414 GVPVDAPDGCIPCSCDPEHA--DGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIP 471
+D+ GC PC+C + DGC G+CHC P G C++CA G+Y +
Sbjct: 942 ---LDSGHGCRPCNCSVAGSVSDGCTD-EGQCHCVPGVAGKRCDRCAHGFYAYQ------ 991
Query: 472 IFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAH-GRCLCRPGVEGPRCDTCRSGFYSF 530
G CDC CD G C+C P +G +C+ C G + +
Sbjct: 992 -------------DGSCTPCDCPHT---QNTCDPETGECVCPPHTQGVKCEECEDGHWGY 1035
Query: 531 PI---CQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACD 587
CQAC CS +GS C VTG C+C+ G+ CD+C G DFP C CD
Sbjct: 1036 DAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFPDCVPCD--CD 1093
Query: 588 PAGTIN-------------SNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKC 633
GT G C CK +V GP C+ C+ + L +NP GCS C C
Sbjct: 1094 LRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCSPCFC 1152
Score = 121 bits (303), Expect = 1e-26
Identities = 61/161 (37%), Positives = 86/161 (53%), Gaps = 18/161 (11%)
Query: 1656 CPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGH-----SNQCQDGSGICVNCQHNT 1710
C P Y+G C+ C+ GYY + + CVPC+C+G+ + C +G C+ C NT
Sbjct: 819 CAPGYSGAWCERCADGYY-GNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNT 877
Query: 1711 AGEHCERCQEGYYGNAVHG-SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERC 1769
G HCERC +G+YG+AV +CRAC C S + C + G C CK TG QC++C
Sbjct: 878 DGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETG--LCDCKPNVTGQQCDQC 935
Query: 1770 APGYFGNPQKFGGSCQPCSCNSNGQL-------GSCHPLTG 1803
GY+G G C+PC+C+ G + G CH + G
Sbjct: 936 LHGYYGLDS--GHGCRPCNCSVAGSVSDGCTDEGQCHCVPG 974
Score = 115 bits (289), Expect = 6e-25
Identities = 72/195 (36%), Positives = 92/195 (47%), Gaps = 34/195 (17%)
Query: 393 CQHNTAGVNCEQCAKGYYR---PYGV-----PVDAPDGCIPCSCDPEHADGCEQGSGRC- 443
C T G +C+ CA GY+R P G P+ AP C+PCSC+ H+D C+ +G+C
Sbjct: 1364 CPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAP--CVPCSCN-NHSDTCDPNTGKCL 1420
Query: 444 HCKPNFHGDNCEKCAIGYYN----FPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVL 499
+C N GD+C+ C GYY + P S P+S P C LEG
Sbjct: 1421 NCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPT--------CVLEGDH 1472
Query: 500 PEICDAHGRCLCRPGVEGPRCDTCRSGFYSFP-----ICQACWCSALGSYQMPCSSVTGQ 554
CDA C G EG C+ C S +Y P CQ C C+ GS C +GQ
Sbjct: 1473 DFRCDA-----CLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQ 1527
Query: 555 CECRPGVTGQRCDRC 569
C CR G +G RCD C
Sbjct: 1528 CVCRLGASGLRCDEC 1542
Score = 111 bits (278), Expect = 1e-23
Identities = 71/223 (31%), Positives = 101/223 (45%), Gaps = 37/223 (16%)
Query: 442 RCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNL-EGVLP 500
+C C+ N G++C +C GY+ P+ VS+ ++ + K DC E V
Sbjct: 289 QCQCEHNTCGESCNRCCPGYHQQPWRPGT----VSSGNTCEACNCHNKAKDCYYDESVAK 344
Query: 501 EICDAH--------GRCL-CRPGVEGPRCDTCRSGFY--------SFPICQACWCSALGS 543
+ + G C+ C G C+TC G+Y C+ C C +GS
Sbjct: 345 QKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGS 404
Query: 544 YQMPC-----------SSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTI 592
C GQC C+ G TG++CDRC G D+P C S C+P G+
Sbjct: 405 LSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCV--SCGCNPVGSA 462
Query: 593 NSN--LGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKC 633
+ G C CK +VEG C RCK ++NL ++NP GCSEC C
Sbjct: 463 SDEPCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFC 505
Score = 108 bits (271), Expect = 7e-23
Identities = 75/266 (28%), Positives = 108/266 (40%), Gaps = 38/266 (14%)
Query: 509 CLCRPGVEGPRCDTCRSGFYSFP------ICQACWCSALGSYQMPCSSVTGQC-ECRPGV 561
C C G G C++C SG+Y ICQ C C + C+ V G C C
Sbjct: 709 CECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHG---HAAECN-VHGVCIACAHNT 764
Query: 562 TGQRCDRCLSGAYDFPHCQGSSSACDPAG---TINSNLGYCQCKLH-------------V 605
TG C++CL G Y P +G+ C P TI SN C L+
Sbjct: 765 TGVHCEQCLPGFYGEPS-RGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGY 823
Query: 606 EGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDC-HCKSHVGGDSCD 664
G C RC Y+ C C C S G C G+C C + G C+
Sbjct: 824 SGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCE 883
Query: 665 TCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENNYYFP 724
C DG++ + C+ C+C + G+ S++C +G+C C+ +V G+ C + + YY
Sbjct: 884 RCADGFYG-DAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGL 942
Query: 725 DLHH--------MKYEIEDGSTPNGR 742
D H + + DG T G+
Sbjct: 943 DSGHGCRPCNCSVAGSVSDGCTDEGQ 968
Score = 107 bits (267), Expect = 2e-22
Identities = 69/220 (31%), Positives = 91/220 (41%), Gaps = 33/220 (15%)
Query: 1265 PCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPR------CKPCSCGRRL 1318
PCECH A C+ G C N G C +C G YG P C+PC+C +
Sbjct: 741 PCECHGHAA---ECNVHGVCIACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTI 797
Query: 1319 CEE-MTGQCR-----------CPPRTVRPQCEVCETHSFSFHPMAG--CEGCNCSRRGTI 1364
+ C C P CE C + + G C C+CS G +
Sbjct: 798 ASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPCDCS--GNV 855
Query: 1365 EAAMP-ECDRDSGQC-RCKPRITGRQCDRCASGFY----RFPECVPCNCNRDGTEPGVCD 1418
+ + CD +G+C +C G C+RCA GFY C C C+ G+ VC
Sbjct: 856 DPSEAGHCDSVTGECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCH 915
Query: 1419 PGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFC 1458
TG C CK NV G +C+ C G + LD + GC C C
Sbjct: 916 LETGLCDCKPNVTGQQCDQCLHGYYGLDSGH--GCRPCNC 953
Score = 98.6 bits (244), Expect = 9e-20
Identities = 63/179 (35%), Positives = 81/179 (45%), Gaps = 22/179 (12%)
Query: 1649 LAVEICACPPAYAGDSCQGCSPGYYRDHKGLYTGR-CVPCNCN---GHSNQCQDGSGICV 1704
L +C C P G C C GYY GL +G C PCNC+ S+ C D G C
Sbjct: 916 LETGLCDCKPNVTGQQCDQCLHGYY----GLDSGHGCRPCNCSVAGSVSDGCTD-EGQC- 969
Query: 1705 NCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGT 1764
+C AG+ C+RC G+Y GSC C CPHT + C G+ C C G
Sbjct: 970 HCVPGVAGKRCDRCAHGFYAYQ-DGSCTPCDCPHTQN---TCDPETGE--CVCPPHTQGV 1023
Query: 1765 QCERCAPGYFGNPQKFGGSCQPCSCNSNGQL-GSCHPLTGDCINQEPKDSSPAEECDDC 1822
+CE C G++G + G CQ C+C+ G C +TG C + K CD C
Sbjct: 1024 KCEECEDGHWGYDAEVG--CQACNCSLVGSTHHRCDVVTGHC---QCKSKFGGRACDQC 1077
Score = 95.9 bits (237), Expect = 6e-19
Identities = 65/228 (28%), Positives = 91/228 (39%), Gaps = 64/228 (28%)
Query: 316 LFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHE-----CEACNCHGHASNCYYDPD 370
L C C T G +C C GY++ + PA ++ C C+C+ H+ C DP+
Sbjct: 1359 LENCVCPPGTVGFSCQDCAPGYHRGKL-PAGSDRGPRPLVAPCVPCSCNNHSDTC--DPN 1415
Query: 371 VERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSC-- 428
G C+NC NTAG +C+ C GY YG + C C+C
Sbjct: 1416 T----------------GKCLNCGDNTAGDHCDVCTSGY---YGKVTGSASDCALCACPH 1456
Query: 429 ------------DPEHADGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVS 476
+ +H C+ C + G +CE+C+ YY P
Sbjct: 1457 SPPASFSPTCVLEGDHDFRCDA------CLLGYEGKHCERCSSSYYGNP----------Q 1500
Query: 477 TPSSEDPVAGDIKGCDCNLEGVLPEICD-AHGRCLCRPGVEGPRCDTC 523
TP G + CDCN G + CD G+C+CR G G RCD C
Sbjct: 1501 TP------GGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDEC 1542
Score = 88.6 bits (218), Expect = 9e-17
Identities = 67/252 (26%), Positives = 90/252 (35%), Gaps = 51/252 (20%)
Query: 443 CHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEI 502
C C P G +C+ CA GY+ P + P+ C CN +
Sbjct: 1362 CVCPPGTVGFSCQDCAPGYHRGKL-------PAGSDRGPRPLVAPCVPCSCNNHS---DT 1411
Query: 503 CDAH-GRCL-CRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQCECRPG 560
CD + G+CL C G CD C SG+Y A C+ P +S + C G
Sbjct: 1412 CDPNTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLE-G 1470
Query: 561 VTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQCKLHVEGPTCSRCKLLYWNL 620
RCD CL LGY EG C RC Y+
Sbjct: 1471 DHDFRCDACL-------------------------LGY-------EGKHCERCSSSYYGN 1498
Query: 621 DKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFG 680
+ C +C C+ G+V G +C + G C C+ G CD CE + +E
Sbjct: 1499 PQTPGGSCQKCDCNPHGSVHG--DCDRTSGQCVCRLGASGLRCDECEPRHILMETD---- 1552
Query: 681 CQGCQCDIGGAL 692
C C + G L
Sbjct: 1553 CVSCDDECVGVL 1564
Score = 84.0 bits (206), Expect = 2e-15
Identities = 71/256 (27%), Positives = 97/256 (37%), Gaps = 72/256 (28%)
Query: 508 RCLCRPGVEGPRCDTCRSGFYSFP----------ICQACWC--SALGSY-------QMPC 548
+C C G C+ C G++ P C+AC C A Y Q
Sbjct: 289 QCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKS 348
Query: 549 SSVTGQ-------CECRPGVTGQRCDRCLSGAYDFPH---------CQGSSSACDPAGTI 592
+ GQ C G C+ C+ G Y PH C+ + CDP G++
Sbjct: 349 LNTAGQFRGGGVCINCLQNTMGINCETCIDGYYR-PHKVSPYEDEPCRPCN--CDPVGSL 405
Query: 593 NS---------------NLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAG 637
+S G C CK G C RC+L Y K+ P+ C C C+ G
Sbjct: 406 SSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGY----KDYPT-CVSCGCNPVG 460
Query: 638 TVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCS 697
+ S C G C CK +V G +CD C+ G++ L++ N GC C C
Sbjct: 461 SASDE-PCT---GPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSEC----------FCF 506
Query: 698 GPSGVCQCREHVVGKV 713
G S VC VG+V
Sbjct: 507 GVSDVCSSLSWPVGQV 522
Score = 77.8 bits (190), Expect = 2e-13
Identities = 55/212 (25%), Positives = 78/212 (36%), Gaps = 53/212 (25%)
Query: 554 QCECRPGVTGQRCDRCLSGAYDFP---------------HCQGSSSAC------------ 586
QC+C G+ C+RC G + P +C + C
Sbjct: 289 QCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKS 348
Query: 587 -DPAGTINSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENP---SGCSECKCHKAGTVSGT 642
+ AG C + G C C Y+ K +P C C C G++S
Sbjct: 349 LNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSV 408
Query: 643 GECRQGD-----------GDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCD-IGG 690
C + D G C CK G+ CD C+ GY +Y C C C+ +G
Sbjct: 409 --CIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGY-----KDYPTCVSCGCNPVGS 461
Query: 691 ALSSMCSGPSGVCQCREHVVGKVCQRPENNYY 722
A C+GP C C+E+V GK C R + +Y
Sbjct: 462 ASDEPCTGP---CVCKENVEGKACDRCKPGFY 490
Score = 71.2 bits (173), Expect = 2e-11
Identities = 58/223 (26%), Positives = 80/223 (35%), Gaps = 38/223 (17%)
Query: 501 EICDAHGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQCECRPG 560
E+ C+C PG G C C G++ ++P S G RP
Sbjct: 1354 EVASLLENCVCPPGTVGFSCQDCAPGYHRG--------------KLPAGSDRGP---RPL 1396
Query: 561 VTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYC-QCKLHVEGPTCSRCKLLYWN 619
V C C C S CDP N G C C + G C C Y+
Sbjct: 1397 VAP--CVPC--------SCNNHSDTCDP------NTGKCLNCGDNTAGDHCDVCTSGYYG 1440
Query: 620 LDKENPSGCSECKCHKAGTVSGTGEC-RQGDGDCHCKSHV---GGDSCDTCEDGYFALEK 675
+ S C+ C C + S + C +GD D C + + G C+ C Y+ +
Sbjct: 1441 KVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQ 1500
Query: 676 SNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPE 718
+ CQ C C+ G++ C SG C CR G C E
Sbjct: 1501 TPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECE 1543
Score = 68.2 bits (165), Expect = 1e-10
Identities = 46/162 (28%), Positives = 71/162 (43%), Gaps = 25/162 (15%)
Query: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 358
C CN H++ C+ N + L C +T G+ CD C +GY + A+ +C C C
Sbjct: 1403 CSCNNHSDTCDPNTGKCL---NCGDNTAGDHCDVCTSGYYGKVTGSAS-----DCALCAC 1454
Query: 359 HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVD 418
H+ + P + +G + C C G +CE+C+ Y YG P
Sbjct: 1455 -PHSPPASFSP-------TCVLEGDH--DFRCDACLLGYEGKHCERCSSSY---YGNPQT 1501
Query: 419 APDGCIPCSCDPE---HADGCEQGSGRCHCKPNFHGDNCEKC 457
C C C+P H D C++ SG+C C+ G C++C
Sbjct: 1502 PGGSCQKCDCNPHGSVHGD-CDRTSGQCVCRLGASGLRCDEC 1542
Score = 62.8 bits (151), Expect = 6e-09
Identities = 32/110 (29%), Positives = 42/110 (38%), Gaps = 16/110 (14%)
Query: 1265 PCECHPTGATGPHC-----------SPEGGQCPCQPNVIGRQCTRCATGHYGFPRCKPCS 1313
PC C P G+ C + GQCPC+ G +C RC G+ +P C C
Sbjct: 396 PCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCG 455
Query: 1314 C---GRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPM--AGCEGCNC 1358
C G E TG C C C+ C+ ++ GC C C
Sbjct: 456 CNPVGSASDEPCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFC 505
Score = 44.3 bits (103), Expect = 0.002
Identities = 20/61 (32%), Positives = 26/61 (42%), Gaps = 2/61 (3%)
Query: 1266 CECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCGRRLCEEMTGQ 1325
C C+P G+ P G C C+ NV G+ C RC G Y P C C ++
Sbjct: 454 CGCNPVGSASDE--PCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFCFGVSDV 511
Query: 1326 C 1326
C
Sbjct: 512 C 512
Score = 40.4 bits (93), Expect = 0.030
Identities = 27/115 (23%), Positives = 47/115 (40%), Gaps = 22/115 (19%)
Query: 1728 HGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQK-----FGG 1782
+G +CP T ++C C+ G C RC PGY P + G
Sbjct: 273 YGHASSCPWDETTK----------KLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGN 322
Query: 1783 SCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMTLLNDLATMG 1837
+C+ C+C++ + C+ + + ++ K + A + C+ L N TMG
Sbjct: 323 TCEACNCHNKAK--DCY--YDESVAKQKKSLNTAGQFRGGGVCINCLQN---TMG 370
Score = 39.7 bits (91), Expect = 0.050
Identities = 19/69 (27%), Positives = 28/69 (40%), Gaps = 15/69 (21%)
Query: 1235 NSFYLDPQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGR 1294
+S+Y +PQT C+ C+C+P G+ C GQC C+ G
Sbjct: 1493 SSYYGNPQTPGGSCQK---------------CDCNPHGSVHGDCDRTSGQCVCRLGASGL 1537
Query: 1295 QCTRCATGH 1303
+C C H
Sbjct: 1538 RCDECEPRH 1546
>gi|219842266 usherin isoform B [Homo sapiens]
Length = 5202
Score = 325 bits (833), Expect = 5e-88
Identities = 201/637 (31%), Positives = 297/637 (46%), Gaps = 61/637 (9%)
Query: 112 KAHPVTNAIDGSERW-WQSPPLSSGTQYNR---VNLTLDLGQLFHVAYILIKFANSPRPD 167
+AHP++ D W S ++ TQ N+ +++ L+ GQ + V YI+I+F SP+P
Sbjct: 338 EAHPLSFVNDNDVGTSWVSNVFTNITQLNQGVTISVDLENGQ-YQVFYIIIQFF-SPQPT 395
Query: 168 LWVLERSVDFGSTYSPWQYFAHSKVDCLKEFGREANMAVTRDDDVLCVTEYSRIVPLENG 227
++R + + WQYFA + FG + N + + D V C+ + S P G
Sbjct: 396 EIRIQRKKENSLDWEDWQYFARN----CGAFGMKNNGDLEKPDSVNCL-QLSNFTPYSRG 450
Query: 228 EVVVSLI----NGRPGAKNFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDPTVT 283
V S++ N RPG NF + +L+EF KAT IR F H
Sbjct: 451 NVTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQIRFHF--------HGQYYTTETAVNL 502
Query: 284 RRYYYSIKDISIGGQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWR 343
R YY++ +I+I G+C C+GHA+ C+ + C + T G CDRC YN + +R
Sbjct: 503 RHRYYAVDEITISGRCQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFR 562
Query: 344 PAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCE 403
+ C+ C C+ H+ +C+Y+ V+ + GGGVC +C+HNT G NCE
Sbjct: 563 QGDQVYAFNCKPCQCNSHSKSCHYNISVD----PFPFEHFRGGGGVCDDCEHNTTGRNCE 618
Query: 404 QCAKGYYRPYGVPVDAPDGCIPCSCDPEHADG----CEQGSGRCHCKPNFHGDNCEKCAI 459
C ++R G A D C PC CD C+Q G+C+CK + G C +C
Sbjct: 619 LCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQN 678
Query: 460 GYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAH---GRCLCRPGVE 516
G+YN DP C+CN G + H G+C C+ V
Sbjct: 679 GFYNL--------------QELDP--DGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVI 722
Query: 517 GPRCDTCRSGF-----YSFPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLS 571
G RCD C GF ++ C+ C C+ GS C+ +GQCEC+ G +CD C
Sbjct: 723 GLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRE 782
Query: 572 GAYDFPHCQGSSSACDPAGTI-----NSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPS 626
Y + CD AG++ N+ G C CK +VEG C++C + L + N
Sbjct: 783 NFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSF 842
Query: 627 GCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQC 686
C C C K GT++G+ C + G C CK V G C+ CE + L N+ CQ C+C
Sbjct: 843 LCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCEC 902
Query: 687 DIGGAL-SSMCSGPSGVCQCREHVVGKVCQRPENNYY 722
D G L ++C SG C C + G+ C + + +Y
Sbjct: 903 DSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFY 939
Score = 160 bits (404), Expect = 3e-38
Identities = 85/239 (35%), Positives = 113/239 (47%), Gaps = 21/239 (8%)
Query: 1248 CKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGF- 1306
C + L +F G PC+C+ G+ C+P GQC C+ G QC C YG
Sbjct: 729 CNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLD 788
Query: 1307 -PRCKPCSCGR------RLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAG--CEGCN 1357
CK C C +C TGQC C P QC C +F C CN
Sbjct: 789 VTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCN 848
Query: 1358 CSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFY-----RFPECVPCNCNRDGT 1412
C + GTI ++ C++ +GQC CK +TG +C++C Y F C C C+ GT
Sbjct: 849 CDKTGTINGSL-LCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGT 907
Query: 1413 EPG-VCDPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFCF---GVNNQCHS 1467
PG +CDP +G CLC N +G CN C+ G F++ P N GC C C VN+ C+S
Sbjct: 908 LPGTICDPISGQCLCVPNRQGRRCNQCQPG-FYISPGNATGCLPCSCHTTGAVNHICNS 965
Score = 153 bits (386), Expect = 3e-36
Identities = 80/216 (37%), Positives = 105/216 (48%), Gaps = 28/216 (12%)
Query: 1265 PCECHPTGATGPH--CSPEGGQCPCQPNVIGRQCTRCATGHYGFPR-----CKPCSC--- 1314
PC+C G C GGQC C+ +V GRQC +C G Y C PC+C
Sbjct: 640 PCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTS 699
Query: 1315 ----GRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPM-----AGCEGCNCSRRGTIE 1365
G C + +GQC+C + +C+ C +F F + GCE C C+ G++
Sbjct: 700 GTVDGDITCHQNSGQCKCKANVIGLRCDHC---NFGFKFLRSFNDVGCEPCQCNLHGSVN 756
Query: 1366 AAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFP--ECVPCNCNRDGTEPG-VCDPGTG 1422
C+ SGQC CK G QCD C FY C C+C+ G+ PG VC+ TG
Sbjct: 757 KF---CNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTG 813
Query: 1423 ACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFC 1458
C+CK NVEG +CN C EG+F+L N C C C
Sbjct: 814 QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNC 849
Score = 147 bits (372), Expect = 1e-34
Identities = 75/231 (32%), Positives = 109/231 (47%), Gaps = 24/231 (10%)
Query: 1248 CKNSARSLVAFYHKGALPCECHPTGATGPH--CSPEGGQCPCQPNVIGRQCTRCATGHYG 1305
C+N +L G PC C+ +G C GQC C+ NVIG +C C G +
Sbjct: 676 CQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFG-FK 734
Query: 1306 FPR------CKPCSCG-----RRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCE 1354
F R C+PC C + C +GQC C QC+ C + + + C+
Sbjct: 735 FLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGL-DVTNCK 793
Query: 1355 GCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPE-----CVPCNCNR 1409
C+C G++ + C+ +GQC CKP + GRQC++C G + + C+PCNC++
Sbjct: 794 ACDCDTAGSLPGTV--CNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDK 851
Query: 1410 DGTEPG--VCDPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFC 1458
GT G +C+ TG C CK V G CN C ++L N + C C C
Sbjct: 852 TGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCEC 902
Score = 142 bits (358), Expect = 6e-33
Identities = 81/261 (31%), Positives = 114/261 (43%), Gaps = 40/261 (15%)
Query: 508 RCLCRPG--VEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQC---------- 555
RCLC EG CD C + P Q A C+S + C
Sbjct: 535 RCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFP 594
Query: 556 ------------ECRPGVTGQRCDRCLSGAYDFPHCQGSSSA--------CDPAGTINSN 595
+C TG+ C+ C Y F SA CD GT N +
Sbjct: 595 FEHFRGGGGVCDDCEHNTTGRNCELCKD--YFFRQVGADPSAIDVCKPCDCDTVGTRNGS 652
Query: 596 L------GYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGD 649
+ G C CK HV G C++C+ ++NL + +P GCS C C+ +GTV G C Q
Sbjct: 653 ILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNS 712
Query: 650 GDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHV 709
G C CK++V G CD C G+ L N GC+ CQC++ G+++ C+ SG C+C++
Sbjct: 713 GQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEA 772
Query: 710 VGKVCQRPENNYYFPDLHHMK 730
G C N+Y D+ + K
Sbjct: 773 KGLQCDTCRENFYGLDVTNCK 793
Score = 138 bits (347), Expect = 1e-31
Identities = 107/351 (30%), Positives = 141/351 (40%), Gaps = 64/351 (18%)
Query: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 358
C CN H V NP +CEC+ G CD C + C+AC+C
Sbjct: 747 CQCNLHGSVNKFCNPHS-GQCECKKEAKGLQCDTCRENFYGL--------DVTNCKACDC 797
Query: 359 HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKG--YYRPYGVP 416
SL A G CI C+ N G C +C +G Y R
Sbjct: 798 D--------------TAGSLPGTVCNAKTGQCI-CKPNVEGRQCNKCLEGNFYLRQNNSF 842
Query: 417 VDAPDGCIPCSCDPEHADG----CEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPI 472
+ C+PC+CD C + +G+C CK G C +C YN L I
Sbjct: 843 L-----CLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYN----LTIDN 893
Query: 473 FPVSTPSSEDPVAGDIKGCDCNLEGVLP-EICDA-HGRCLCRPGVEGPRCDTCRSGFYSF 530
F + C+C+ G LP ICD G+CLC P +G RC+ C+ GFY
Sbjct: 894 FQ------------HCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYIS 941
Query: 531 PI----CQACWCSALGSYQMPCSSVTGQCECRPG-VTGQRCDRCLSGAYDFPHCQGSSSA 585
P C C C G+ C+S+TGQC C+ + GQRCD+C + F G
Sbjct: 942 PGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQP 1001
Query: 586 CDP--AGTINSNL----GYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSE 630
C+ +G +N G C CK V G C C +LD N GCS+
Sbjct: 1002 CNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGCSK 1052
Score = 134 bits (337), Expect = 2e-30
Identities = 70/213 (32%), Positives = 98/213 (46%), Gaps = 28/213 (13%)
Query: 1268 CHPTGATGP----HCSPEGGQCP-CQPNVIGRQCTRCATGHY--------GFPRCKPCSC 1314
CH + P H GG C C+ N GR C C + CKPC C
Sbjct: 584 CHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDC 643
Query: 1315 -------GRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMA--GCEGCNCSRRGTIE 1365
G LC+++ GQC C QC C+ ++ + GC CNC+ GT++
Sbjct: 644 DTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVD 703
Query: 1366 AAMPECDRDSGQCRCKPRITGRQCDRCASGF-----YRFPECVPCNCNRDGTEPGVCDPG 1420
+ C ++SGQC+CK + G +CD C GF + C PC CN G+ C+P
Sbjct: 704 GDIT-CHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPH 762
Query: 1421 TGACLCKENVEGTECNVCREGSFHLDPANLKGC 1453
+G C CK+ +G +C+ CRE + LD N K C
Sbjct: 763 SGQCECKKEAKGLQCDTCRENFYGLDVTNCKAC 795
Score = 130 bits (326), Expect = 3e-29
Identities = 70/211 (33%), Positives = 98/211 (46%), Gaps = 24/211 (11%)
Query: 1264 LPCECHPTGATGPH--CSPEGGQCPCQPNVIGRQCTRCATGHYG-----FPRCKPCSCGR 1316
LPC C TG C+ GQCPC+ V G +C +C Y F C+ C C
Sbjct: 845 LPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDS 904
Query: 1317 ------RLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHP--MAGCEGCNCSRRGTIEAAM 1368
+C+ ++GQC C P +C C+ F P GC C+C G +
Sbjct: 905 LGTLPGTICDPISGQCLCVPNRQGRRCNQCQP-GFYISPGNATGCLPCSCHTTGAVNHI- 962
Query: 1369 PECDRDSGQCRCKPR-ITGRQCDRCASGFYRFP----ECVPCNCNRDGTEPGVCDPGTGA 1423
C+ +GQC C+ I G++CD+C ++ F C PCNC+ G C TG
Sbjct: 963 --CNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQ 1020
Query: 1424 CLCKENVEGTECNVCREGSFHLDPANLKGCT 1454
C CK+ V G++C+ C + HLD NL GC+
Sbjct: 1021 CFCKQFVTGSKCDACVPSASHLDVNNLLGCS 1051
Score = 99.0 bits (245), Expect = 7e-20
Identities = 56/199 (28%), Positives = 89/199 (44%), Gaps = 33/199 (16%)
Query: 1653 ICACPPAYAGDSCQGCSPGY----YRDHKGLYTGRCVPCNCNGHSNQC------------ 1696
+C+ G C C P Y +R +Y C PC CN HS C
Sbjct: 537 LCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFE 596
Query: 1697 --QDGSGICVNCQHNTAGEHCERCQEGYYGN-----AVHGSCRACPCPH--TNSFATGCV 1747
+ G G+C +C+HNT G +CE C++ ++ + C+ C C T + + C
Sbjct: 597 HFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCD 656
Query: 1748 VNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLG---SCHPLTGD 1804
GG +C+CK +G QC +C G++ + C PC+CN++G + +CH +G
Sbjct: 657 QIGG--QCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQ 714
Query: 1805 CINQEPKDSSPAEECDDCD 1823
C + K + CD C+
Sbjct: 715 C---KCKANVIGLRCDHCN 730
Score = 87.4 bits (215), Expect = 2e-16
Identities = 51/158 (32%), Positives = 68/158 (43%), Gaps = 10/158 (6%)
Query: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQ---CQDGSGICVNCQHNT 1710
C C G C C+ G+ + + C PC CN H + C SG C C+
Sbjct: 715 CKCKANVIGLRCDHCNFGF-KFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQC-ECKKEA 772
Query: 1711 AGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCA 1770
G C+ C+E +YG V +C+AC C S G V N +C CK G QC +C
Sbjct: 773 KGLQCDTCRENFYGLDVT-NCKACDCDTAGSLP-GTVCNAKTGQCICKPNVEGRQCNKCL 830
Query: 1771 PGYFGNPQKFGGSCQPCSCNSNGQLGS---CHPLTGDC 1805
G F Q C PC+C+ G + C+ TG C
Sbjct: 831 EGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQC 868
Score = 87.0 bits (214), Expect = 3e-16
Identities = 52/179 (29%), Positives = 77/179 (43%), Gaps = 18/179 (10%)
Query: 1654 CACPPAYAGDSCQGCSPG--YYRDHKGLYTGRCVPCNCN-----GHSNQCQDGSGICVNC 1706
C C P G C C G Y R + C+PCNC+ S C +G C C
Sbjct: 815 CICKPNVEGRQCNKCLEGNFYLRQNNSFL---CLPCNCDKTGTINGSLLCNKSTGQCP-C 870
Query: 1707 QHNTAGEHCERCQEGYYGNAVHG--SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGT 1764
+ G C +C+ Y + C+ C C + G + + +C C G
Sbjct: 871 KLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLP-GTICDPISGQCLCVPNRQGR 929
Query: 1765 QCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGS-CHPLTGDCINQEPKDSSPAEECDDC 1822
+C +C PG++ +P G C PCSC++ G + C+ LTG C+ Q+ S + CD C
Sbjct: 930 RCNQCQPGFYISPGNATG-CLPCSCHTTGAVNHICNSLTGQCVCQDA--SIAGQRCDQC 985
Score = 85.1 bits (209), Expect = 1e-15
Identities = 61/183 (33%), Positives = 81/183 (44%), Gaps = 24/183 (13%)
Query: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQ----CQDGSGICVNCQHN 1709
C C G C C P Y + C C C+ C SG C+ C N
Sbjct: 868 CPCKLGVTGLRCNQCEPHRYNLTIDNFQ-HCQMCECDSLGTLPGTICDPISGQCL-CVPN 925
Query: 1710 TAGEHCERCQEGYY---GNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCK-AGYTGTQ 1765
G C +CQ G+Y GNA C C C HT A + N +C C+ A G +
Sbjct: 926 RQGRRCNQCQPGFYISPGNAT--GCLPCSC-HTTG-AVNHICNSLTGQCVCQDASIAGQR 981
Query: 1766 CERCAPGYFG-NPQKFGGSCQPCSCNSNGQLG-SCHPLTGDCINQEPKDSSPAEECDDCD 1823
C++C YFG +PQ G CQPC+C+ +G L +CH +TG C ++ S CD
Sbjct: 982 CDQCKDHYFGFDPQT--GRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGS------KCD 1033
Query: 1824 SCV 1826
+CV
Sbjct: 1034 ACV 1036
Score = 82.8 bits (203), Expect = 5e-15
Identities = 48/174 (27%), Positives = 70/174 (40%), Gaps = 13/174 (7%)
Query: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQ----CQDGSGICVNCQHN 1709
C C G C C +Y GL C C+C+ + C +G C+ C+ N
Sbjct: 766 CECKKEAKGLQCDTCRENFY----GLDVTNCKACDCDTAGSLPGTVCNAKTGQCI-CKPN 820
Query: 1710 TAGEHCERCQEGYYGNAVHGS--CRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCE 1767
G C +C EG + + S C C C T + + N +C CK G TG +C
Sbjct: 821 VEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCN 880
Query: 1768 RCAPGYFGNPQKFGGSCQPCSCNSNGQLGS--CHPLTGDCINQEPKDSSPAEEC 1819
+C P + CQ C C+S G L C P++G C+ + +C
Sbjct: 881 QCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQC 934
Score = 80.5 bits (197), Expect = 3e-14
Identities = 77/335 (22%), Positives = 140/335 (41%), Gaps = 40/335 (11%)
Query: 3029 GTKNSFMALYLSKGRLVFALGTDGKKLRIKSK----EKCNDGKWHTVVFGHDGEKGRLVV 3084
G + + AL L KGRL F G + + + ++ +DGKWH ++ G++ +
Sbjct: 1564 GNQEEYFALQLKKGRLYFLFDPQGSPVEVTTTNDHGKQYSDGKWHEIIAIRHQAFGQITL 1623
Query: 3085 DGLRAREGS-LPGNSTISIRAPVYLGSPPSG-----KPKSLPTNSFVGCLKNFQLDSKPL 3138
DG+ + L G++ I V+LG P K + FVGCLK+
Sbjct: 1624 DGIYTGSSAILNGSTVIGDNTGVFLGGLPRSYTILRKDPEIIQKGFVGCLKDVHFMKN-- 1681
Query: 3139 YTPSSSFGVSSCLGGPLEKGIYFSEEGG------------------HVVLAHSVLLGPEF 3180
Y PS+ + + +Y S EG H + H G F
Sbjct: 1682 YNPSAIWEPLDWQSSEEQINVYNSWEGCPASLNEGAQFLGAGFLELHPYMFHG---GMNF 1738
Query: 3181 KLVFSIRPRSLTGILIHIGSQPG-KHLCVYLEAGKVTASMDSGAGGTSTSVTPKQSLCDG 3239
++ F R L G+L+ + ++ G L + L++G +T +++ T + S C+G
Sbjct: 1739 EISFKFRTDQLNGLLLFVYNKDGPDFLAMELKSGILTFRLNTSLAFTQVDLLLGLSYCNG 1798
Query: 3240 QWHSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGAPANL--TTLRIPVWK 3297
+W+ V + + + ++ + A + P P+++GG P L + + + +
Sbjct: 1799 KWNKVIIKKEGSFISASVNGLMKH-ASESGDQPLVVNSPVYVGGIPQELLNSYQHLCLEQ 1857
Query: 3298 SFFGCLRNIHVNHIPVPVTEALEVQGP--VSLNGC 3330
F GC++++ V V A G V+L+GC
Sbjct: 1858 GFGGCMKDVKFTRGAV-VNLASVSSGAVRVNLDGC 1891
Score = 80.1 bits (196), Expect = 3e-14
Identities = 58/203 (28%), Positives = 77/203 (37%), Gaps = 33/203 (16%)
Query: 356 CN-CHGHASNCYYDPDVERQQASLNTQGIYAG------GGVCINCQHNTAGVNCEQCAKG 408
CN C H N D Q ++ G G G C+ C N G C QC G
Sbjct: 879 CNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCL-CVPNRQGRRCNQCQPG 937
Query: 409 YYRPYGVPVDAPDGCIPCSCDPEHADG--CEQGSGRCHCKP-NFHGDNCEKCAIGYYNFP 465
+Y G GC+PCSC A C +G+C C+ + G C++C Y+ F
Sbjct: 938 FYISPGNAT----GCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGF- 992
Query: 466 FCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICD-AHGRCLCRPGVEGPRCDTCR 524
DP G + C+C+L G L E C G+C C+ V G +CD C
Sbjct: 993 ----------------DPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACV 1036
Query: 525 SGFYSFPICQACWCSALGSYQMP 547
+ CS Q P
Sbjct: 1037 PSASHLDVNNLLGCSKTPFQQPP 1059
Score = 79.0 bits (193), Expect = 8e-14
Identities = 53/182 (29%), Positives = 78/182 (42%), Gaps = 24/182 (13%)
Query: 1656 CPPAYAGDSCQGCSPGYYR----DHKGLYTGRCVPCNCN-----GHSNQCQDGSGICVNC 1706
C G +C+ C ++R D + C PC+C+ S C G C NC
Sbjct: 608 CEHNTTGRNCELCKDYFFRQVGADPSAIDV--CKPCDCDTVGTRNGSILCDQIGGQC-NC 664
Query: 1707 QHNTAGEHCERCQEGYYG--NAVHGSCRACPCPHTNSFATG---CVVNGGDVRCSCKAGY 1761
+ + +G C +CQ G+Y C C C +T+ G C N G +C CKA
Sbjct: 665 KRHVSGRQCNQCQNGFYNLQELDPDGCSPCNC-NTSGTVDGDITCHQNSG--QCKCKANV 721
Query: 1762 TGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGS-CHPLTGDCINQEPKDSSPAEECD 1820
G +C+ C G+ C+PC CN +G + C+P +G C E K + +CD
Sbjct: 722 IGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQC---ECKKEAKGLQCD 778
Query: 1821 DC 1822
C
Sbjct: 779 TC 780
Score = 75.5 bits (184), Expect = 8e-13
Identities = 42/122 (34%), Positives = 63/122 (51%), Gaps = 8/122 (6%)
Query: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCN--GHSNQ-CQDGSGICVNCQHNT 1710
C C P G C C PG+Y G TG C+PC+C+ G N C +G CV +
Sbjct: 920 CLCVPNRQGRRCNQCQPGFYIS-PGNATG-CLPCSCHTTGAVNHICNSLTGQCVCQDASI 977
Query: 1711 AGEHCERCQEGYYG-NAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERC 1769
AG+ C++C++ Y+G + G C+ C C + + C + G +C CK TG++C+ C
Sbjct: 978 AGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTG--QCFCKQFVTGSKCDAC 1035
Query: 1770 AP 1771
P
Sbjct: 1036 VP 1037
Score = 71.6 bits (174), Expect = 1e-11
Identities = 33/89 (37%), Positives = 46/89 (51%), Gaps = 10/89 (11%)
Query: 1262 GALPCECHPTGATGPHCSPEGGQCPCQ-PNVIGRQCTRCATGHYGFP----RCKPCSCG- 1315
G LPC CH TGA C+ GQC CQ ++ G++C +C ++GF RC+PC+C
Sbjct: 947 GCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHL 1006
Query: 1316 ----RRLCEEMTGQCRCPPRTVRPQCEVC 1340
C +TGQC C +C+ C
Sbjct: 1007 SGALNETCHLVTGQCFCKQFVTGSKCDAC 1035
Score = 58.2 bits (139), Expect = 1e-07
Identities = 50/182 (27%), Positives = 72/182 (39%), Gaps = 38/182 (20%)
Query: 1672 YYRDHKGLYTGRCVPCNCNGHSNQCQDGSG--ICVNCQHN-TAGEHCERCQEGY------ 1722
YY + +GRC C+GH++ C S C+ Q + T G HC+RC Y
Sbjct: 506 YYAVDEITISGRC---QCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFR 562
Query: 1723 YGNAVHG-SCRACPCPHTNSFATGCVVN-------------GGDVRCSCKAGYTGTQCER 1768
G+ V+ +C+ C C NS + C N GG V C+ TG CE
Sbjct: 563 QGDQVYAFNCKPCQC---NSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCEL 619
Query: 1769 CAPGYF---GNPQKFGGSCQPCSCNSNGQLGS---CHPLTGDCINQEPKDSSPAEECDDC 1822
C +F G C+PC C++ G C + G C K +C+ C
Sbjct: 620 CKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQC---NCKRHVSGRQCNQC 676
Query: 1823 DS 1824
+
Sbjct: 677 QN 678
Score = 32.3 bits (72), Expect = 8.1
Identities = 34/129 (26%), Positives = 61/129 (47%), Gaps = 19/129 (14%)
Query: 2633 GLLFFAEN--GDRFISLNIEDGKLMVRYKLNSELPKERG---VGDAINNGRDHSIQIKIG 2687
GLL F N G F+++ ++ G ++ ++LN+ L + +G + NG+ + + IK
Sbjct: 1751 GLLLFVYNKDGPDFLAMELKSG--ILTFRLNTSLAFTQVDLLLGLSYCNGKWNKVIIK-- 1806
Query: 2688 KLQKRMWINVDVQNTII------DGEVFDFSTYYLGGIPIAIRERFN--ISTPAFRGCMK 2739
++ +I+ V + D + S Y+GGIP + + F GCMK
Sbjct: 1807 --KEGSFISASVNGLMKHASESGDQPLVVNSPVYVGGIPQELLNSYQHLCLEQGFGGCMK 1864
Query: 2740 NLKKTSGVV 2748
++K T G V
Sbjct: 1865 DVKFTRGAV 1873
>gi|219842259 usherin isoform A [Homo sapiens]
Length = 1546
Score = 325 bits (833), Expect = 5e-88
Identities = 201/637 (31%), Positives = 297/637 (46%), Gaps = 61/637 (9%)
Query: 112 KAHPVTNAIDGSERW-WQSPPLSSGTQYNR---VNLTLDLGQLFHVAYILIKFANSPRPD 167
+AHP++ D W S ++ TQ N+ +++ L+ GQ + V YI+I+F SP+P
Sbjct: 338 EAHPLSFVNDNDVGTSWVSNVFTNITQLNQGVTISVDLENGQ-YQVFYIIIQFF-SPQPT 395
Query: 168 LWVLERSVDFGSTYSPWQYFAHSKVDCLKEFGREANMAVTRDDDVLCVTEYSRIVPLENG 227
++R + + WQYFA + FG + N + + D V C+ + S P G
Sbjct: 396 EIRIQRKKENSLDWEDWQYFARN----CGAFGMKNNGDLEKPDSVNCL-QLSNFTPYSRG 450
Query: 228 EVVVSLI----NGRPGAKNFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDPTVT 283
V S++ N RPG NF + +L+EF KAT IR F H
Sbjct: 451 NVTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQIRFHF--------HGQYYTTETAVNL 502
Query: 284 RRYYYSIKDISIGGQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWR 343
R YY++ +I+I G+C C+GHA+ C+ + C + T G CDRC YN + +R
Sbjct: 503 RHRYYAVDEITISGRCQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFR 562
Query: 344 PAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCE 403
+ C+ C C+ H+ +C+Y+ V+ + GGGVC +C+HNT G NCE
Sbjct: 563 QGDQVYAFNCKPCQCNSHSKSCHYNISVD----PFPFEHFRGGGGVCDDCEHNTTGRNCE 618
Query: 404 QCAKGYYRPYGVPVDAPDGCIPCSCDPEHADG----CEQGSGRCHCKPNFHGDNCEKCAI 459
C ++R G A D C PC CD C+Q G+C+CK + G C +C
Sbjct: 619 LCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQN 678
Query: 460 GYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAH---GRCLCRPGVE 516
G+YN DP C+CN G + H G+C C+ V
Sbjct: 679 GFYNL--------------QELDP--DGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVI 722
Query: 517 GPRCDTCRSGF-----YSFPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLS 571
G RCD C GF ++ C+ C C+ GS C+ +GQCEC+ G +CD C
Sbjct: 723 GLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRE 782
Query: 572 GAYDFPHCQGSSSACDPAGTI-----NSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPS 626
Y + CD AG++ N+ G C CK +VEG C++C + L + N
Sbjct: 783 NFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSF 842
Query: 627 GCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQC 686
C C C K GT++G+ C + G C CK V G C+ CE + L N+ CQ C+C
Sbjct: 843 LCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCEC 902
Query: 687 DIGGAL-SSMCSGPSGVCQCREHVVGKVCQRPENNYY 722
D G L ++C SG C C + G+ C + + +Y
Sbjct: 903 DSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFY 939
Score = 160 bits (404), Expect = 3e-38
Identities = 85/239 (35%), Positives = 113/239 (47%), Gaps = 21/239 (8%)
Query: 1248 CKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGF- 1306
C + L +F G PC+C+ G+ C+P GQC C+ G QC C YG
Sbjct: 729 CNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLD 788
Query: 1307 -PRCKPCSCGR------RLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAG--CEGCN 1357
CK C C +C TGQC C P QC C +F C CN
Sbjct: 789 VTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCN 848
Query: 1358 CSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFY-----RFPECVPCNCNRDGT 1412
C + GTI ++ C++ +GQC CK +TG +C++C Y F C C C+ GT
Sbjct: 849 CDKTGTINGSL-LCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGT 907
Query: 1413 EPG-VCDPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFCF---GVNNQCHS 1467
PG +CDP +G CLC N +G CN C+ G F++ P N GC C C VN+ C+S
Sbjct: 908 LPGTICDPISGQCLCVPNRQGRRCNQCQPG-FYISPGNATGCLPCSCHTTGAVNHICNS 965
Score = 153 bits (386), Expect = 3e-36
Identities = 80/216 (37%), Positives = 105/216 (48%), Gaps = 28/216 (12%)
Query: 1265 PCECHPTGATGPH--CSPEGGQCPCQPNVIGRQCTRCATGHYGFPR-----CKPCSC--- 1314
PC+C G C GGQC C+ +V GRQC +C G Y C PC+C
Sbjct: 640 PCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTS 699
Query: 1315 ----GRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPM-----AGCEGCNCSRRGTIE 1365
G C + +GQC+C + +C+ C +F F + GCE C C+ G++
Sbjct: 700 GTVDGDITCHQNSGQCKCKANVIGLRCDHC---NFGFKFLRSFNDVGCEPCQCNLHGSVN 756
Query: 1366 AAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFP--ECVPCNCNRDGTEPG-VCDPGTG 1422
C+ SGQC CK G QCD C FY C C+C+ G+ PG VC+ TG
Sbjct: 757 KF---CNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTG 813
Query: 1423 ACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFC 1458
C+CK NVEG +CN C EG+F+L N C C C
Sbjct: 814 QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNC 849
Score = 147 bits (372), Expect = 1e-34
Identities = 75/231 (32%), Positives = 109/231 (47%), Gaps = 24/231 (10%)
Query: 1248 CKNSARSLVAFYHKGALPCECHPTGATGPH--CSPEGGQCPCQPNVIGRQCTRCATGHYG 1305
C+N +L G PC C+ +G C GQC C+ NVIG +C C G +
Sbjct: 676 CQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFG-FK 734
Query: 1306 FPR------CKPCSCG-----RRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCE 1354
F R C+PC C + C +GQC C QC+ C + + + C+
Sbjct: 735 FLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGL-DVTNCK 793
Query: 1355 GCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPE-----CVPCNCNR 1409
C+C G++ + C+ +GQC CKP + GRQC++C G + + C+PCNC++
Sbjct: 794 ACDCDTAGSLPGTV--CNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDK 851
Query: 1410 DGTEPG--VCDPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFC 1458
GT G +C+ TG C CK V G CN C ++L N + C C C
Sbjct: 852 TGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCEC 902
Score = 142 bits (358), Expect = 6e-33
Identities = 81/261 (31%), Positives = 114/261 (43%), Gaps = 40/261 (15%)
Query: 508 RCLCRPG--VEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQC---------- 555
RCLC EG CD C + P Q A C+S + C
Sbjct: 535 RCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFP 594
Query: 556 ------------ECRPGVTGQRCDRCLSGAYDFPHCQGSSSA--------CDPAGTINSN 595
+C TG+ C+ C Y F SA CD GT N +
Sbjct: 595 FEHFRGGGGVCDDCEHNTTGRNCELCKD--YFFRQVGADPSAIDVCKPCDCDTVGTRNGS 652
Query: 596 L------GYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGD 649
+ G C CK HV G C++C+ ++NL + +P GCS C C+ +GTV G C Q
Sbjct: 653 ILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNS 712
Query: 650 GDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHV 709
G C CK++V G CD C G+ L N GC+ CQC++ G+++ C+ SG C+C++
Sbjct: 713 GQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEA 772
Query: 710 VGKVCQRPENNYYFPDLHHMK 730
G C N+Y D+ + K
Sbjct: 773 KGLQCDTCRENFYGLDVTNCK 793
Score = 138 bits (347), Expect = 1e-31
Identities = 107/351 (30%), Positives = 141/351 (40%), Gaps = 64/351 (18%)
Query: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 358
C CN H V NP +CEC+ G CD C + C+AC+C
Sbjct: 747 CQCNLHGSVNKFCNPHS-GQCECKKEAKGLQCDTCRENFYGL--------DVTNCKACDC 797
Query: 359 HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKG--YYRPYGVP 416
SL A G CI C+ N G C +C +G Y R
Sbjct: 798 D--------------TAGSLPGTVCNAKTGQCI-CKPNVEGRQCNKCLEGNFYLRQNNSF 842
Query: 417 VDAPDGCIPCSCDPEHADG----CEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPI 472
+ C+PC+CD C + +G+C CK G C +C YN L I
Sbjct: 843 L-----CLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYN----LTIDN 893
Query: 473 FPVSTPSSEDPVAGDIKGCDCNLEGVLP-EICDA-HGRCLCRPGVEGPRCDTCRSGFYSF 530
F + C+C+ G LP ICD G+CLC P +G RC+ C+ GFY
Sbjct: 894 FQ------------HCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYIS 941
Query: 531 PI----CQACWCSALGSYQMPCSSVTGQCECRPG-VTGQRCDRCLSGAYDFPHCQGSSSA 585
P C C C G+ C+S+TGQC C+ + GQRCD+C + F G
Sbjct: 942 PGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQP 1001
Query: 586 CDP--AGTINSNL----GYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSE 630
C+ +G +N G C CK V G C C +LD N GCS+
Sbjct: 1002 CNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGCSK 1052
Score = 134 bits (337), Expect = 2e-30
Identities = 70/213 (32%), Positives = 98/213 (46%), Gaps = 28/213 (13%)
Query: 1268 CHPTGATGP----HCSPEGGQCP-CQPNVIGRQCTRCATGHY--------GFPRCKPCSC 1314
CH + P H GG C C+ N GR C C + CKPC C
Sbjct: 584 CHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDC 643
Query: 1315 -------GRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMA--GCEGCNCSRRGTIE 1365
G LC+++ GQC C QC C+ ++ + GC CNC+ GT++
Sbjct: 644 DTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVD 703
Query: 1366 AAMPECDRDSGQCRCKPRITGRQCDRCASGF-----YRFPECVPCNCNRDGTEPGVCDPG 1420
+ C ++SGQC+CK + G +CD C GF + C PC CN G+ C+P
Sbjct: 704 GDIT-CHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPH 762
Query: 1421 TGACLCKENVEGTECNVCREGSFHLDPANLKGC 1453
+G C CK+ +G +C+ CRE + LD N K C
Sbjct: 763 SGQCECKKEAKGLQCDTCRENFYGLDVTNCKAC 795
Score = 130 bits (326), Expect = 3e-29
Identities = 70/211 (33%), Positives = 98/211 (46%), Gaps = 24/211 (11%)
Query: 1264 LPCECHPTGATGPH--CSPEGGQCPCQPNVIGRQCTRCATGHYG-----FPRCKPCSCGR 1316
LPC C TG C+ GQCPC+ V G +C +C Y F C+ C C
Sbjct: 845 LPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDS 904
Query: 1317 ------RLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHP--MAGCEGCNCSRRGTIEAAM 1368
+C+ ++GQC C P +C C+ F P GC C+C G +
Sbjct: 905 LGTLPGTICDPISGQCLCVPNRQGRRCNQCQP-GFYISPGNATGCLPCSCHTTGAVNHI- 962
Query: 1369 PECDRDSGQCRCKPR-ITGRQCDRCASGFYRFP----ECVPCNCNRDGTEPGVCDPGTGA 1423
C+ +GQC C+ I G++CD+C ++ F C PCNC+ G C TG
Sbjct: 963 --CNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQ 1020
Query: 1424 CLCKENVEGTECNVCREGSFHLDPANLKGCT 1454
C CK+ V G++C+ C + HLD NL GC+
Sbjct: 1021 CFCKQFVTGSKCDACVPSASHLDVNNLLGCS 1051
Score = 99.0 bits (245), Expect = 7e-20
Identities = 56/199 (28%), Positives = 89/199 (44%), Gaps = 33/199 (16%)
Query: 1653 ICACPPAYAGDSCQGCSPGY----YRDHKGLYTGRCVPCNCNGHSNQC------------ 1696
+C+ G C C P Y +R +Y C PC CN HS C
Sbjct: 537 LCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFE 596
Query: 1697 --QDGSGICVNCQHNTAGEHCERCQEGYYGN-----AVHGSCRACPCPH--TNSFATGCV 1747
+ G G+C +C+HNT G +CE C++ ++ + C+ C C T + + C
Sbjct: 597 HFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCD 656
Query: 1748 VNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLG---SCHPLTGD 1804
GG +C+CK +G QC +C G++ + C PC+CN++G + +CH +G
Sbjct: 657 QIGG--QCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQ 714
Query: 1805 CINQEPKDSSPAEECDDCD 1823
C + K + CD C+
Sbjct: 715 C---KCKANVIGLRCDHCN 730
Score = 87.4 bits (215), Expect = 2e-16
Identities = 51/158 (32%), Positives = 68/158 (43%), Gaps = 10/158 (6%)
Query: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQ---CQDGSGICVNCQHNT 1710
C C G C C+ G+ + + C PC CN H + C SG C C+
Sbjct: 715 CKCKANVIGLRCDHCNFGF-KFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQC-ECKKEA 772
Query: 1711 AGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCA 1770
G C+ C+E +YG V +C+AC C S G V N +C CK G QC +C
Sbjct: 773 KGLQCDTCRENFYGLDVT-NCKACDCDTAGSLP-GTVCNAKTGQCICKPNVEGRQCNKCL 830
Query: 1771 PGYFGNPQKFGGSCQPCSCNSNGQLGS---CHPLTGDC 1805
G F Q C PC+C+ G + C+ TG C
Sbjct: 831 EGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQC 868
Score = 87.0 bits (214), Expect = 3e-16
Identities = 52/179 (29%), Positives = 77/179 (43%), Gaps = 18/179 (10%)
Query: 1654 CACPPAYAGDSCQGCSPG--YYRDHKGLYTGRCVPCNCN-----GHSNQCQDGSGICVNC 1706
C C P G C C G Y R + C+PCNC+ S C +G C C
Sbjct: 815 CICKPNVEGRQCNKCLEGNFYLRQNNSFL---CLPCNCDKTGTINGSLLCNKSTGQCP-C 870
Query: 1707 QHNTAGEHCERCQEGYYGNAVHG--SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGT 1764
+ G C +C+ Y + C+ C C + G + + +C C G
Sbjct: 871 KLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLP-GTICDPISGQCLCVPNRQGR 929
Query: 1765 QCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGS-CHPLTGDCINQEPKDSSPAEECDDC 1822
+C +C PG++ +P G C PCSC++ G + C+ LTG C+ Q+ S + CD C
Sbjct: 930 RCNQCQPGFYISPGNATG-CLPCSCHTTGAVNHICNSLTGQCVCQDA--SIAGQRCDQC 985
Score = 85.1 bits (209), Expect = 1e-15
Identities = 61/183 (33%), Positives = 81/183 (44%), Gaps = 24/183 (13%)
Query: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQ----CQDGSGICVNCQHN 1709
C C G C C P Y + C C C+ C SG C+ C N
Sbjct: 868 CPCKLGVTGLRCNQCEPHRYNLTIDNFQ-HCQMCECDSLGTLPGTICDPISGQCL-CVPN 925
Query: 1710 TAGEHCERCQEGYY---GNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCK-AGYTGTQ 1765
G C +CQ G+Y GNA C C C HT A + N +C C+ A G +
Sbjct: 926 RQGRRCNQCQPGFYISPGNAT--GCLPCSC-HTTG-AVNHICNSLTGQCVCQDASIAGQR 981
Query: 1766 CERCAPGYFG-NPQKFGGSCQPCSCNSNGQLG-SCHPLTGDCINQEPKDSSPAEECDDCD 1823
C++C YFG +PQ G CQPC+C+ +G L +CH +TG C ++ S CD
Sbjct: 982 CDQCKDHYFGFDPQT--GRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGS------KCD 1033
Query: 1824 SCV 1826
+CV
Sbjct: 1034 ACV 1036
Score = 82.8 bits (203), Expect = 5e-15
Identities = 48/174 (27%), Positives = 70/174 (40%), Gaps = 13/174 (7%)
Query: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQ----CQDGSGICVNCQHN 1709
C C G C C +Y GL C C+C+ + C +G C+ C+ N
Sbjct: 766 CECKKEAKGLQCDTCRENFY----GLDVTNCKACDCDTAGSLPGTVCNAKTGQCI-CKPN 820
Query: 1710 TAGEHCERCQEGYYGNAVHGS--CRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCE 1767
G C +C EG + + S C C C T + + N +C CK G TG +C
Sbjct: 821 VEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCN 880
Query: 1768 RCAPGYFGNPQKFGGSCQPCSCNSNGQLGS--CHPLTGDCINQEPKDSSPAEEC 1819
+C P + CQ C C+S G L C P++G C+ + +C
Sbjct: 881 QCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQC 934
Score = 80.1 bits (196), Expect = 3e-14
Identities = 58/203 (28%), Positives = 77/203 (37%), Gaps = 33/203 (16%)
Query: 356 CN-CHGHASNCYYDPDVERQQASLNTQGIYAG------GGVCINCQHNTAGVNCEQCAKG 408
CN C H N D Q ++ G G G C+ C N G C QC G
Sbjct: 879 CNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCL-CVPNRQGRRCNQCQPG 937
Query: 409 YYRPYGVPVDAPDGCIPCSCDPEHADG--CEQGSGRCHCKP-NFHGDNCEKCAIGYYNFP 465
+Y G GC+PCSC A C +G+C C+ + G C++C Y+ F
Sbjct: 938 FYISPGNAT----GCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGF- 992
Query: 466 FCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICD-AHGRCLCRPGVEGPRCDTCR 524
DP G + C+C+L G L E C G+C C+ V G +CD C
Sbjct: 993 ----------------DPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACV 1036
Query: 525 SGFYSFPICQACWCSALGSYQMP 547
+ CS Q P
Sbjct: 1037 PSASHLDVNNLLGCSKTPFQQPP 1059
Score = 79.0 bits (193), Expect = 8e-14
Identities = 53/182 (29%), Positives = 78/182 (42%), Gaps = 24/182 (13%)
Query: 1656 CPPAYAGDSCQGCSPGYYR----DHKGLYTGRCVPCNCN-----GHSNQCQDGSGICVNC 1706
C G +C+ C ++R D + C PC+C+ S C G C NC
Sbjct: 608 CEHNTTGRNCELCKDYFFRQVGADPSAIDV--CKPCDCDTVGTRNGSILCDQIGGQC-NC 664
Query: 1707 QHNTAGEHCERCQEGYYG--NAVHGSCRACPCPHTNSFATG---CVVNGGDVRCSCKAGY 1761
+ + +G C +CQ G+Y C C C +T+ G C N G +C CKA
Sbjct: 665 KRHVSGRQCNQCQNGFYNLQELDPDGCSPCNC-NTSGTVDGDITCHQNSG--QCKCKANV 721
Query: 1762 TGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGS-CHPLTGDCINQEPKDSSPAEECD 1820
G +C+ C G+ C+PC CN +G + C+P +G C E K + +CD
Sbjct: 722 IGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQC---ECKKEAKGLQCD 778
Query: 1821 DC 1822
C
Sbjct: 779 TC 780
Score = 75.5 bits (184), Expect = 8e-13
Identities = 42/122 (34%), Positives = 63/122 (51%), Gaps = 8/122 (6%)
Query: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCN--GHSNQ-CQDGSGICVNCQHNT 1710
C C P G C C PG+Y G TG C+PC+C+ G N C +G CV +
Sbjct: 920 CLCVPNRQGRRCNQCQPGFYIS-PGNATG-CLPCSCHTTGAVNHICNSLTGQCVCQDASI 977
Query: 1711 AGEHCERCQEGYYG-NAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERC 1769
AG+ C++C++ Y+G + G C+ C C + + C + G +C CK TG++C+ C
Sbjct: 978 AGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTG--QCFCKQFVTGSKCDAC 1035
Query: 1770 AP 1771
P
Sbjct: 1036 VP 1037
Score = 71.6 bits (174), Expect = 1e-11
Identities = 33/89 (37%), Positives = 46/89 (51%), Gaps = 10/89 (11%)
Query: 1262 GALPCECHPTGATGPHCSPEGGQCPCQ-PNVIGRQCTRCATGHYGFP----RCKPCSCG- 1315
G LPC CH TGA C+ GQC CQ ++ G++C +C ++GF RC+PC+C
Sbjct: 947 GCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHL 1006
Query: 1316 ----RRLCEEMTGQCRCPPRTVRPQCEVC 1340
C +TGQC C +C+ C
Sbjct: 1007 SGALNETCHLVTGQCFCKQFVTGSKCDAC 1035
Score = 58.2 bits (139), Expect = 1e-07
Identities = 50/182 (27%), Positives = 72/182 (39%), Gaps = 38/182 (20%)
Query: 1672 YYRDHKGLYTGRCVPCNCNGHSNQCQDGSG--ICVNCQHN-TAGEHCERCQEGY------ 1722
YY + +GRC C+GH++ C S C+ Q + T G HC+RC Y
Sbjct: 506 YYAVDEITISGRC---QCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFR 562
Query: 1723 YGNAVHG-SCRACPCPHTNSFATGCVVN-------------GGDVRCSCKAGYTGTQCER 1768
G+ V+ +C+ C C NS + C N GG V C+ TG CE
Sbjct: 563 QGDQVYAFNCKPCQC---NSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCEL 619
Query: 1769 CAPGYF---GNPQKFGGSCQPCSCNSNGQLGS---CHPLTGDCINQEPKDSSPAEECDDC 1822
C +F G C+PC C++ G C + G C K +C+ C
Sbjct: 620 CKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQC---NCKRHVSGRQCNQC 676
Query: 1823 DS 1824
+
Sbjct: 677 QN 678
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 313 bits (803), Expect = 1e-84
Identities = 200/566 (35%), Positives = 260/566 (45%), Gaps = 63/566 (11%)
Query: 1274 TGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPR------CKPCSCG--RRLCEEMTGQ 1325
TG + E QC C P G C C TG+ P C+ CSC CE TG
Sbjct: 1115 TGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETGA 1174
Query: 1326 CR-CPPRTVRPQCEVCETHSFSFHPMA---GCEGCNCSRRGTIEAAMPECDRDSG---QC 1378
C+ C T P+CE C+ + C+ C C A C D+ C
Sbjct: 1175 CQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTC 1234
Query: 1379 -RCKPRITGRQCDRCASGFY-------------RFPECVPCNCNRDGTEPGVCDPGTGAC 1424
C P +GR C+RCA G+Y + P + CNC+ G+ CD G C
Sbjct: 1235 DACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCD-AAGQC 1293
Query: 1425 LCKENVEGTECNVCREGSFHLDPANLKGCTSCFCFGVNNQCHSSHKRRTKFVDMLGWHLE 1484
CK VEG C+ CR FHL +N GC CFC G+ QC SS R ++ H
Sbjct: 1294 QCKAQVEGLTCSHCRPHHFHLSASNPDGCLPCFCMGITQQCASSAYTR----HLISTHFA 1349
Query: 1485 TADRVDIPVSFNPGSNSMVAD---LQELPATIH------------SASWVAPTSYLGDKV 1529
D + NP NS + ++ +P S W P +Y GDKV
Sbjct: 1350 PGDFQGFAL-VNPQRNSRLTGEFTVEPVPEGAQLSFGNFAQLGHESFYWQLPETYQGDKV 1408
Query: 1530 SSYGGYLTYQAKSFGLPGDMVLLEKKPDVQLTGQHMSIIYEETNTPRPDRLHHGRVHVVE 1589
++YGG L Y P L + PDVQ+TG ++ ++ + P+R + + E
Sbjct: 1409 AAYGGKLRYTLSYTAGPQGSPLSD--PDVQITGNNIMLVASQPALQGPERRSYEIMFREE 1466
Query: 1590 GNFRHASSRAPVSREELMTVLSRLADVRIQGLYFTETQRLTLSEVGLEEASDTGSGRI-A 1648
F P +RE L+ L+ L ++ I+ + + ++S V LE A S R A
Sbjct: 1467 --FWRRPDGQPATREHLLMALADLDELLIRATFSSVPLAASISAVSLEVAQPGPSNRPRA 1524
Query: 1649 LAVEICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQH 1708
L VE C CPP Y G SCQ C+PGY R GLY G C C CNGHS+ C +G C CQH
Sbjct: 1525 LEVEECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQCQH 1584
Query: 1709 NTAGEHCERCQEGYYGNAVHGS---CRACPCPHT---NSFATGC-VVNGGDVRC-SCKAG 1760
N AGE CE C GYYG+A G+ C+ C CP T N F+ C + G RC +C+ G
Sbjct: 1585 NAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPG 1644
Query: 1761 YTGTQCERCAPGYFGNPQKFGGSCQP 1786
YTG CE+C PGY GNP GG C P
Sbjct: 1645 YTGQYCEQCGPGYVGNPSVQGGQCLP 1670
Score = 271 bits (694), Expect = 6e-72
Identities = 184/569 (32%), Positives = 249/569 (43%), Gaps = 52/569 (9%)
Query: 1284 QCPCQPNVIGRQCTRCATGHYGFP------RCKPCSCGRRL--CEEMTGQC-RCPPRTVR 1334
+C C G C C P C C+C C+ + G C C T
Sbjct: 730 ECRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCNGHASSCDPVYGHCLNCQHNTEG 789
Query: 1335 PQCEVCETHSFSFHPMA---GCEGCNCSRRGTIEAAMPECDRDS-GQCRCK---PRITGR 1387
PQC C+ F A C C C C D+ GQ C P TGR
Sbjct: 790 PQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYTGR 849
Query: 1388 QCDRCASGFYRFPECVPCNCNRDGTEPGVCDP----GTG--ACLCKENVEGTECNVCREG 1441
+C+ CA G+ P C E CD GT AC CK NV G CN C +G
Sbjct: 850 RCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEACRCKNNVVGRLCNECADG 909
Query: 1442 SFHLDPANLKGCTSCFCFGVNNQCHSSHKRRTKF--VDMLGWHLETADRVDIPVS----F 1495
SFHL N GC CFC GV+ C SS R + H + + F
Sbjct: 910 SFHLSTRNPDGCLKCFCMGVSRHCTSSSWSRAQLHGASEEPGHFSLTNAASTHTTNEGIF 969
Query: 1496 NPGSNSM-VADLQELPATIHSASWVAPTSYLGDKVSSYGGYLTYQAKSFGLPGDMVLLEK 1554
+P + + L + + W P+ +LGDKV+SYGG L + PG L
Sbjct: 970 SPTPGELGFSSFHRLLSGPYF--WSLPSRFLGDKVTSYGGELRFTVTQRSQPGS-TPLHG 1026
Query: 1555 KPDVQLTGQHMSIIYEETNTPRPDRLHHGRVHVVEGNFRHASSRAPVSREELMTVLSRLA 1614
+P V L G ++ + + P P + V E ++ + P +RE L+ L+ +
Sbjct: 1027 QPLVVLQGNNIILEHHVAQEPSPGQPSTFIVPFREQAWQRPDGQ-PATREHLLMALAGID 1085
Query: 1615 DVRIQGLYFTETQRLTLSEVGLEEASDTGSGR-IALAVEICACPPAYAGDSCQGCSPGYY 1673
+ I+ Y + +S + ++ A +G+ AL VE C+CPP Y G SCQ C GY
Sbjct: 1086 TLLIRASYAQQPAESRVSGISMDVAVPEETGQDPALEVEQCSCPPGYRGPSCQDCDTGYT 1145
Query: 1674 RDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGS--- 1730
R GLY G C C+C+GHS C+ +G C CQH+T G CE+CQ GYYG+A G+
Sbjct: 1146 RTPSGLYLGTCERCSCHGHSEACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQD 1205
Query: 1731 CRACPC---PHTNSFATGCVVN-GGDVRC-SCKAGYTGTQCERCAPGYFGNPQKFGGSCQ 1785
C+ CPC P A C ++ G C +C G++G CERCAPGY+GNP + G CQ
Sbjct: 1206 CQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQ-GQPCQ 1264
Query: 1786 ---------PCSCNSNGQLGSCHPLTGDC 1805
C+C+ G + S G C
Sbjct: 1265 RDSQVPGPIGCNCDPQGSVSSQCDAAGQC 1293
Score = 228 bits (581), Expect = 8e-59
Identities = 133/392 (33%), Positives = 203/392 (51%), Gaps = 41/392 (10%)
Query: 1438 CREGSFHLDPANLKGCTSCFCFGVNNQCHSSHKRRTKFVDMLGWHLETADR---VDIPVS 1494
C +G F+L+ + C CFCFG+ + C S+ + F D + + D V++ +
Sbjct: 505 CPDGHFYLEHS--AACLPCFCFGITSVCQSTRR----FRDQIRLRFDQPDDFKGVNVTMP 558
Query: 1495 FNPGSNSMVADLQELPAT--------------IHSASWVAPTSYLGDKVSSYGGYLTYQA 1540
PG+ + + ++ + +H + W P +LG+KV SYGG L Y
Sbjct: 559 AQPGTPPLSSTQLQIDPSLHEFQLVDLSRRFLVHDSFWALPEQFLGNKVDSYGGSLRYNV 618
Query: 1541 KSFGLPGDMVLLEKKPDVQLTGQHMSIIYEETNTPRPDRLHHGRVHVVEGNFRHASSRAP 1600
+ + L M+ ++PDV L G ++ +P L+ +V E ++ H S R P
Sbjct: 619 R-YELARGMLEPVQRPDVVLMGAGYRLLSRGHTPTQPGALNQRQVQFSEEHWVHESGR-P 676
Query: 1601 VSREELMTVLSRLADVRIQGLYFTETQRLTLSEVGLEEASD--TGSGRIALAVEICACPP 1658
V R EL+ VL L V IQ +Y T+ + LS++ ++ T GR A +VE C CP
Sbjct: 677 VQRAELLQVLQSLEAVLIQTVYNTKMASVGLSDIAMDTTVTHATSHGR-AHSVEECRCPI 735
Query: 1659 AYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERC 1718
Y+G SC+ C + R G Y G C CNCNGH++ C G C+NCQHNT G C +C
Sbjct: 736 GYSGLSCESCDAHFTRVPGGPYLGTCSGCNCNGHASSCDPVYGHCLNCQHNTEGPQCNKC 795
Query: 1719 QEGYYGNAVHG---SCRACPCPHTNS---FATGCVVN-GGDVRC-SCKAGYTGTQCERCA 1770
+ G++G+A+ SCR CPCP+ ++ F+ C ++ G C +C GYTG +CE CA
Sbjct: 796 KAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYTGRRCESCA 855
Query: 1771 PGYFGNPQKFGGSCQPCS-----CNSNGQLGS 1797
PGY GNP + GG C+P + C+ G +G+
Sbjct: 856 PGYEGNPIQPGGKCRPVNQEIVRCDERGSMGT 887
Score = 113 bits (282), Expect = 4e-24
Identities = 75/238 (31%), Positives = 95/238 (39%), Gaps = 46/238 (19%)
Query: 318 RCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQAS 377
+C C G +C C TGY R + CE C+CHGH+ C +P+
Sbjct: 1125 QCSCPPGYRGPSCQDCDTGYT----RTPSGLYLGTCERCSCHGHSEAC--EPET------ 1172
Query: 378 LNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYY--RPYGVPVDAPDGCIPCSCDP---EH 432
G C CQH+T G CEQC GYY G P D PC DP +
Sbjct: 1173 ----------GACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQ--LCPCYGDPAAGQA 1220
Query: 433 ADGC---EQGSGRCH-CKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDI 488
A C G C C P G +CE+CA GYY P P D
Sbjct: 1221 AHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNP--------SQGQPCQRDSQVPGP 1272
Query: 489 KGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPI-----CQACWCSAL 541
GC+C+ +G + CDA G+C C+ VEG C CR + C C+C +
Sbjct: 1273 IGCNCDPQGSVSSQCDAAGQCQCKAQVEGLTCSHCRPHHFHLSASNPDGCLPCFCMGI 1330
Score = 108 bits (269), Expect = 1e-22
Identities = 72/221 (32%), Positives = 95/221 (42%), Gaps = 47/221 (21%)
Query: 442 RCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPE 501
+C C P + G +C+ C GY P L + G + C C+ E
Sbjct: 1125 QCSCPPGYRGPSCQDCDTGYTRTPSGLYL---------------GTCERCSCHGHS---E 1166
Query: 502 ICDAH-GRCL-CRPGVEGPRCDTCRSGFYSFPI------CQACWC---SALGSYQMPCSS 550
C+ G C C+ EGPRC+ C+ G+Y CQ C C A G C
Sbjct: 1167 ACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFL 1226
Query: 551 VTG---QCE-CRPGVTGQRCDRCLSGAYDFPH----CQGSSSA-------CDPAGTINSN 595
T C+ C PG +G+ C+RC G Y P CQ S CDP G+++S
Sbjct: 1227 DTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQ 1286
Query: 596 L---GYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKC 633
G CQCK VEG TCS C+ +++L NP GC C C
Sbjct: 1287 CDAAGQCQCKAQVEGLTCSHCRPHHFHLSASNPDGCLPCFC 1327
Score = 90.5 bits (223), Expect = 2e-17
Identities = 62/214 (28%), Positives = 91/214 (42%), Gaps = 41/214 (19%)
Query: 443 CHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEI 502
C C + G +CE C + P P G GC+CN
Sbjct: 731 CRCPIGYSGLSCESCDAHFTRVP---------------GGPYLGTCSGCNCNGHA---SS 772
Query: 503 CD-AHGRCL-CRPGVEGPRCDTCRSGFYSFPI------CQACWCSALGS---YQMPCSSV 551
CD +G CL C+ EGP+C+ C++GF+ + C+ C C + + + C
Sbjct: 773 CDPVYGHCLNCQHNTEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLD 832
Query: 552 T-GQ--CE-CRPGVTGQRCDRCLSGAYDFPHCQGSSSA--------CDPAGTINSNLGYC 599
T GQ C+ C PG TG+RC+ C G P G CD G++ ++ C
Sbjct: 833 TDGQATCDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEAC 892
Query: 600 QCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKC 633
+CK +V G C+ C ++L NP GC +C C
Sbjct: 893 RCKNNVVGRLCNECADGSFHLSTRNPDGCLKCFC 926
Score = 87.8 bits (216), Expect = 2e-16
Identities = 62/213 (29%), Positives = 81/213 (38%), Gaps = 40/213 (18%)
Query: 554 QCECRPGVTGQRCDRCLSGAYDFPH-----------CQGSSSACDPAGTINSNLGYCQ-C 601
QC C PG G C C +G P C G S AC+P G CQ C
Sbjct: 1125 QCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEP------ETGACQGC 1178
Query: 602 KLHVEGPTCSRCKLLYW-NLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCH-----CK 655
+ H EGP C +C+ Y+ + + P C C C+ D D H C
Sbjct: 1179 QHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACS 1238
Query: 656 SHVGGDSCDTCEDGYFALEKSNYFGCQ---------GCQCDIGGALSSMCSGPSGVCQCR 706
G C+ C GY+ S CQ GC CD G++SS C +G CQC+
Sbjct: 1239 PGHSGRHCERCAPGYYG-NPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDA-AGQCQCK 1296
Query: 707 EHVVGKVCQRPENNYYFPDLHHMKYEIEDGSTP 739
V G C +++ H+ DG P
Sbjct: 1297 AQVEGLTCSHCRPHHF-----HLSASNPDGCLP 1324
Score = 83.2 bits (204), Expect = 4e-15
Identities = 53/172 (30%), Positives = 72/172 (41%), Gaps = 34/172 (19%)
Query: 298 QCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACN 357
+C C+GH+E C PE CQHHT G C++C GY + A +C+ C
Sbjct: 1158 RCSCHGHSEAC---EPETGACQGCQHHTEGPRCEQCQPGY----YGDAQRGTPQDCQLCP 1210
Query: 358 CHGH------ASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYY- 410
C+G A C+ D D G C C +G +CE+CA GYY
Sbjct: 1211 CYGDPAAGQAAHTCFLDTD---------------GHPTCDACSPGHSGRHCERCAPGYYG 1255
Query: 411 -RPYGVPVDAPD---GCIPCSCDPEHADGCE-QGSGRCHCKPNFHGDNCEKC 457
G P G I C+CDP+ + + +G+C CK G C C
Sbjct: 1256 NPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAAGQCQCKAQVEGLTCSHC 1307
Score = 83.2 bits (204), Expect = 4e-15
Identities = 51/156 (32%), Positives = 65/156 (41%), Gaps = 33/156 (21%)
Query: 319 CECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASL 378
C C G +C C GY R + CE C C+GH+ C+ +
Sbjct: 1530 CRCPPGYIGLSCQDCAPGYT----RTGSGLYLGHCELCECNGHSDLCHPET--------- 1576
Query: 379 NTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSC---DPEH--A 433
G C CQHN AG CE CA GYY P+ C PC+C +PE+ +
Sbjct: 1577 ---------GACSQCQHNAAGEFCELCAPGYYG--DATAGTPEDCQPCACPLTNPENMFS 1625
Query: 434 DGCEQ---GSGRC-HCKPNFHGDNCEKCAIGYYNFP 465
CE G RC C+P + G CE+C GY P
Sbjct: 1626 RTCESLGAGGYRCTACEPGYTGQYCEQCGPGYVGNP 1661
Score = 82.4 bits (202), Expect = 7e-15
Identities = 67/241 (27%), Positives = 91/241 (37%), Gaps = 54/241 (22%)
Query: 319 CECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASL 378
C C G +C+ C + + P C CNC+GHAS+C DP
Sbjct: 731 CRCPIGYSGLSCESCDAHFTRVPGGPYLGT----CSGCNCNGHASSC--DP--------- 775
Query: 379 NTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDA-PDGCIPCSC-----DPEH 432
+Y G C+NCQHNT G C +C G+ +G + A C PC C
Sbjct: 776 ----VY---GHCLNCQHNTEGPQCNKCKAGF---FGDAMKATATSCRPCPCPYIDASRRF 825
Query: 433 ADGC---EQGSGRCH-CKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDI 488
+D C G C C P + G CE CA GY P+ PV +I
Sbjct: 826 SDTCFLDTDGQATCDACAPGYTGRRCESCAPGYEG---------NPIQPGGKCRPVNQEI 876
Query: 489 KGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPI-----CQACWCSALGS 543
CD G + +A C C+ V G C+ C G + C C+C +
Sbjct: 877 VRCD--ERGSMGTSGEA---CRCKNNVVGRLCNECADGSFHLSTRNPDGCLKCFCMGVSR 931
Query: 544 Y 544
+
Sbjct: 932 H 932
Score = 67.8 bits (164), Expect = 2e-10
Identities = 57/215 (26%), Positives = 83/215 (38%), Gaps = 42/215 (19%)
Query: 505 AHGR------CLCRPGVEGPRCDTCRSGFYSFP------ICQACWCSALGSYQMPCSSVT 552
+HGR C C G G C++C + F P C C C+ S C V
Sbjct: 721 SHGRAHSVEECRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCNGHAS---SCDPVY 777
Query: 553 GQC-ECRPGVTGQRCDRCLSGAY-DFPHCQGSSSACDPAGTINSNLGYCQ-CKLHVEGP- 608
G C C+ G +C++C +G + D +S P I+++ + C L +G
Sbjct: 778 GHCLNCQHNTEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQA 837
Query: 609 TCSRCKLLYWNLDKEN-----------------PSGCSECKCHKAGTVSGTGECRQGDGD 651
TC C Y E+ P +C + G++ +GE
Sbjct: 838 TCDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEA------ 891
Query: 652 CHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQC 686
C CK++V G C+ C DG F L N GC C C
Sbjct: 892 CRCKNNVVGRLCNECADGSFHLSTRNPDGCLKCFC 926
Score = 65.1 bits (157), Expect = 1e-09
Identities = 50/176 (28%), Positives = 66/176 (37%), Gaps = 38/176 (21%)
Query: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 358
C CNGHA C +P CQH+T G C++C G+ + A + C C C
Sbjct: 764 CNCNGHASSC---DPVYGHCLNCQHNTEGPQCNKCKAGF----FGDAMKATATSCRPCPC 816
Query: 359 ------HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRP 412
+ C+ D D G C C G CE CA GY
Sbjct: 817 PYIDASRRFSDTCFLDTD---------------GQATCDACAPGYTGRRCESCAPGY--- 858
Query: 413 YGVPVDAPDGCIPCSCDPEHADGCEQGS-----GRCHCKPNFHGDNCEKCAIGYYN 463
G P+ C P + + D E+GS C CK N G C +CA G ++
Sbjct: 859 EGNPIQPGGKCRPVNQEIVRCD--ERGSMGTSGEACRCKNNVVGRLCNECADGSFH 912
Score = 62.8 bits (151), Expect = 6e-09
Identities = 39/127 (30%), Positives = 55/127 (43%), Gaps = 19/127 (14%)
Query: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 358
C CNGH+++C+ PE +CQH+ GE C+ C GY + A +C+ C C
Sbjct: 1563 CECNGHSDLCH---PETGACSQCQHNAAGEFCELCAPGY----YGDATAGTPEDCQPCAC 1615
Query: 359 HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVD 418
+P+ S + + AGG C C+ G CEQC GY G P
Sbjct: 1616 P------LTNPE---NMFSRTCESLGAGGYRCTACEPGYTGQYCEQCGPGY---VGNPSV 1663
Query: 419 APDGCIP 425
C+P
Sbjct: 1664 QGGQCLP 1670
Score = 61.6 bits (148), Expect = 1e-08
Identities = 38/132 (28%), Positives = 65/132 (49%), Gaps = 10/132 (7%)
Query: 3014 VDMQTTSSRGLVFHTGTK-------NSFMALYLSKGRLVFALGTDGKKLRIKSKEKCNDG 3066
++++T+++ GL+ G + F++L L G LVF + R+ S++ NDG
Sbjct: 4232 LEVRTSTASGLLLWQGVEVGEAGQGKDFISLGLQDGHLVFRYQLGSGEARLVSEDPINDG 4291
Query: 3067 KWHTVVFGHDGEKGRLVVDGLRAREGSLPG-NSTISIRAPVYLGSPP--SGKPKSLPTNS 3123
+WH V +G +G + VDG G PG N ++ + VY+G P + ++
Sbjct: 4292 EWHRVTALREGRRGSIQVDGEELVSGRSPGPNVAVNAKGSVYIGGAPDVATLTGGRFSSG 4351
Query: 3124 FVGCLKNFQLDS 3135
GC+KN L S
Sbjct: 4352 ITGCVKNLVLHS 4363
Score = 60.8 bits (146), Expect = 2e-08
Identities = 45/180 (25%), Positives = 70/180 (38%), Gaps = 25/180 (13%)
Query: 554 QCECRPGVTGQRCDRCLSGAYDFP-----------HCQGSSSACDPAGTINSNLGYC-QC 601
+C C G +G C+ C + P +C G +S+CDP G+C C
Sbjct: 730 ECRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCNGHASSCDPV------YGHCLNC 783
Query: 602 KLHVEGPTCSRCKL-LYWNLDKENPSGCSECKCHKAGTVSGTGEC----RQGDGDCH-CK 655
+ + EGP C++CK + + K + C C C + G C C
Sbjct: 784 QHNTEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACA 843
Query: 656 SHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSG-VCQCREHVVGKVC 714
G C++C GY C+ +I G SG C+C+ +VVG++C
Sbjct: 844 PGYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEACRCKNNVVGRLC 903
Score = 55.8 bits (133), Expect = 7e-07
Identities = 43/154 (27%), Positives = 58/154 (37%), Gaps = 33/154 (21%)
Query: 443 CHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEI 502
C C P + G +C+ CA GY T + G + C+CN ++
Sbjct: 1530 CRCPPGYIGLSCQDCAPGY---------------TRTGSGLYLGHCELCECNGHS---DL 1571
Query: 503 CDAH-GRCL-CRPGVEGPRCDTCRSGFYSFPI------CQACWCSALGSYQM---PCSSV 551
C G C C+ G C+ C G+Y CQ C C M C S+
Sbjct: 1572 CHPETGACSQCQHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESL 1631
Query: 552 TG---QCE-CRPGVTGQRCDRCLSGAYDFPHCQG 581
+C C PG TGQ C++C G P QG
Sbjct: 1632 GAGGYRCTACEPGYTGQYCEQCGPGYVGNPSVQG 1665
Score = 53.1 bits (126), Expect = 4e-06
Identities = 26/69 (37%), Positives = 35/69 (50%), Gaps = 5/69 (7%)
Query: 1755 CSCKAGYTGTQCERCAPGYFGNPQK-FGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDS 1813
C C GY G C+ CAPGY + G C+ C CN + L CHP TG C + + +
Sbjct: 1530 CRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDL--CHPETGAC--SQCQHN 1585
Query: 1814 SPAEECDDC 1822
+ E C+ C
Sbjct: 1586 AAGEFCELC 1594
Score = 50.4 bits (119), Expect = 3e-05
Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 5/69 (7%)
Query: 1755 CSCKAGYTGTQCERCAPGYFGNPQ-KFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDS 1813
C C GY+G CE C + P + G+C C+CN G SC P+ G C+N +
Sbjct: 731 CRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCN--GHASSCDPVYGHCLNCQHNTE 788
Query: 1814 SPAEECDDC 1822
P +C+ C
Sbjct: 789 GP--QCNKC 795
Score = 47.0 bits (110), Expect = 3e-04
Identities = 21/65 (32%), Positives = 27/65 (41%), Gaps = 1/65 (1%)
Query: 1262 GALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCGRRLCEE 1321
G + C C P G+ C GQC C+ V G C+ C H+ P C C
Sbjct: 1271 GPIGCNCDPQGSVSSQCD-AAGQCQCKAQVEGLTCSHCRPHHFHLSASNPDGCLPCFCMG 1329
Query: 1322 MTGQC 1326
+T QC
Sbjct: 1330 ITQQC 1334
Score = 46.2 bits (108), Expect = 5e-04
Identities = 42/165 (25%), Positives = 55/165 (33%), Gaps = 31/165 (18%)
Query: 524 RSGFYSFPICQACWCSAL-----GSYQMPCSSVTGQCECRPGVTGQRCDRCL-------S 571
R+ F S P+ + +L G P + +C C PG G C C S
Sbjct: 1494 RATFSSVPLAASISAVSLEVAQPGPSNRPRALEVEECRCPPGYIGLSCQDCAPGYTRTGS 1553
Query: 572 GAY----DFPHCQGSSSACDPAGTINSNLGYC-QCKLHVEGPTCSRCKLLYW-NLDKENP 625
G Y + C G S C P G C QC+ + G C C Y+ + P
Sbjct: 1554 GLYLGHCELCECNGHSDLCHP------ETGACSQCQHNAAGEFCELCAPGYYGDATAGTP 1607
Query: 626 SGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGY 670
C C C + + G GG C CE GY
Sbjct: 1608 EDCQPCACPLTNPENMFSRTCESLG-------AGGYRCTACEPGY 1645
Score = 43.9 bits (102), Expect = 0.003
Identities = 23/74 (31%), Positives = 33/74 (44%), Gaps = 5/74 (6%)
Query: 651 DCHCKSHVGGDSCDTCEDGYFALEKSNYFG-CQGCQCDIGGALSSMCSGPSGVC-QCREH 708
+C C G SC C GY Y G C+ C+C+ S +C +G C QC+ +
Sbjct: 1529 ECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECN---GHSDLCHPETGACSQCQHN 1585
Query: 709 VVGKVCQRPENNYY 722
G+ C+ YY
Sbjct: 1586 AAGEFCELCAPGYY 1599
Score = 43.1 bits (100), Expect = 0.005
Identities = 40/148 (27%), Positives = 64/148 (43%), Gaps = 11/148 (7%)
Query: 3014 VDMQTTSSRGLVFHTGTKNS----FMALYLSKGRLVFALGTDGKKLRIKSKEKCNDGKWH 3069
V+ + + G++ +G K+ F++L + G L F ++S E G+WH
Sbjct: 3955 VEFKPLAPDGVLLFSGGKSGPVEDFVSLAMVGGHLEFRYELGSGLAVLRSAEPLALGRWH 4014
Query: 3070 TVVFGHDGEKGRLVVDGLRAREGSLPGNST-ISIRAPVYLGSPPSGKPKSLPTN---SFV 3125
V + G L V+G R S PG S +++ +YLG P S TN F
Sbjct: 4015 RVSAERLNKDGSLRVNGGRPVLRSSPGKSQGLNLHTLLYLGGVEPSVPLSPATNMSAHFR 4074
Query: 3126 GCLKNFQLDSKPL---YTPSSSFGVSSC 3150
GC+ ++ K L Y+ S G+ C
Sbjct: 4075 GCVGEVSVNGKRLDLTYSFLGSQGIGQC 4102
Score = 39.7 bits (91), Expect = 0.050
Identities = 45/163 (27%), Positives = 66/163 (40%), Gaps = 31/163 (19%)
Query: 2602 YFEGTGYARVP------TQPHAPIPTFGQTIQTTVDRGLLFF-------AENGDRFISLN 2648
YF G+ P + P P T ++T+ GLL + A G FISL
Sbjct: 4205 YFHDDGFLAFPGHVFSRSLPEVP-ETIELEVRTSTASGLLLWQGVEVGEAGQGKDFISLG 4263
Query: 2649 IEDGKLMVRYKLNS---ELPKERGVGD-------AINNGRDHSIQIKIGKLQKRMWINVD 2698
++DG L+ RY+L S L E + D A+ GR SIQ+ +L V
Sbjct: 4264 LQDGHLVFRYQLGSGEARLVSEDPINDGEWHRVTALREGRRGSIQVDGEEL-------VS 4316
Query: 2699 VQNTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNL 2741
++ + V + Y+GG P + GC+KNL
Sbjct: 4317 GRSPGPNVAVNAKGSVYIGGAPDVATLTGGRFSSGITGCVKNL 4359
Score = 38.1 bits (87), Expect = 0.15
Identities = 18/66 (27%), Positives = 25/66 (37%), Gaps = 6/66 (9%)
Query: 1267 ECHPTGATGPHCSPEGGQ------CPCQPNVIGRQCTRCATGHYGFPRCKPCSCGRRLCE 1320
+C P C G C C+ NV+GR C CA G + P C + C
Sbjct: 868 KCRPVNQEIVRCDERGSMGTSGEACRCKNNVVGRLCNECADGSFHLSTRNPDGCLKCFCM 927
Query: 1321 EMTGQC 1326
++ C
Sbjct: 928 GVSRHC 933
Score = 35.8 bits (81), Expect = 0.73
Identities = 32/159 (20%), Positives = 62/159 (38%), Gaps = 19/159 (11%)
Query: 3011 QFAVDMQTTSSRGLVFHTGTKN-------------SFMALYLSKGRLVFALGTDGKKLRI 3057
+ + + S+ G++ + G K F++ L GR F I
Sbjct: 3687 EIKITFRPDSADGMLLYNGQKRVPGSPTNLANRQPDFISFGLVGGRPEFRFDAGSGMATI 3746
Query: 3058 KSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGN-STISIRAPVYLGSPP--SG 3114
+ G +HTV +G L+V L G+ G + + +YLG P
Sbjct: 3747 RHPTPLALGHFHTVTLLRSLTQGSLIVGDLAPVNGTSQGKFQGLDLNEELYLGGYPDYGA 3806
Query: 3115 KPKSLPTNSFVGCLKNFQLDSKPLYTPS---SSFGVSSC 3150
PK+ ++ F+GC++ ++ + + ++ G+S C
Sbjct: 3807 IPKAGLSSGFIGCVRELRIQGEEIVFHDLNLTAHGISHC 3845
Score = 33.9 bits (76), Expect = 2.8
Identities = 27/89 (30%), Positives = 34/89 (38%), Gaps = 15/89 (16%)
Query: 1681 TGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHTN 1740
T R PC G + + S +CV C G CE Q A+H AC T
Sbjct: 3847 TCRDRPCQNGGQCHDSESSSYVCV-CPAGFTGSRCEHSQ------ALHCHPEACGPDAT- 3898
Query: 1741 SFATGCV--VNGGDVRCSCKAGYTGTQCE 1767
CV +G C C G +G +CE
Sbjct: 3899 -----CVNRPDGRGYTCRCHLGRSGLRCE 3922
Score = 32.7 bits (73), Expect = 6.2
Identities = 40/158 (25%), Positives = 63/158 (39%), Gaps = 20/158 (12%)
Query: 2440 GNKDASRDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAVMDRVKFQRIYQFA 2499
G D++ +A+V G L Y LG A L+ + L RV +R+ +
Sbjct: 3971 GKSGPVEDFVSLAMVGGHLEFRYELGSGLAVLRSAEPLALGR-----WHRVSAERLNKDG 4025
Query: 2500 RLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKL-PSRLSFPPY 2558
L G + +PG G N +TLL Y+GG P L P+ +
Sbjct: 4026 SLRVNGGRPVLR-SSPG--KSQGLNLHTLL---------YLGGVEPSVPLSPATNMSAHF 4073
Query: 2559 KGCIELDDLNENVLSL-YNFKKTFNLNTT-EVEPCRRR 2594
+GC+ +N L L Y+F + + + PC R+
Sbjct: 4074 RGCVGEVSVNGKRLDLTYSFLGSQGIGQCYDSSPCERQ 4111
>gi|110611156 laminin, gamma 3 precursor [Homo sapiens]
Length = 1575
Score = 295 bits (754), Expect = 7e-79
Identities = 197/614 (32%), Positives = 282/614 (45%), Gaps = 95/614 (15%)
Query: 1266 CECHPTGATGPHCSPE-GGQ--CPCQPNVIGRQCTRCATGHYGFP----------RCKPC 1312
C+C+ + C P+ GQ C CQ N G C RC P C PC
Sbjct: 271 CKCNGHAS---ECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPC 327
Query: 1313 SCGRRLCEEMT------------GQCR-CPPRTVRPQCEVCETHSFSFHPMAGCEGCNCS 1359
+C R EE T G+C C T P CE C+ + + + P C+ C+C
Sbjct: 328 NCSGR-SEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQ 386
Query: 1360 RRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPE--CVPCNCNRDGTEPGVC 1417
G++ +CD D+G C CKP +TG +CDRC GF+ E C PC CN G+ C
Sbjct: 387 SAGSLHL---QCD-DTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLD-TC 441
Query: 1418 DPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFCFGVNNQCHSSHKRRTKFV- 1476
DP +G C CKENVEG C+ CR G+F+L P N GC+SCFC+G + C S+ + + +
Sbjct: 442 DPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYGHSKVCASTAQFQVHHIL 501
Query: 1477 -----DMLGWHLETADRVDIPVSFNPGSNSMVADLQELPATIHSASWVAPTSYLGDKVSS 1531
GW + + P ++P + + +E AP +LGD+ S
Sbjct: 502 SDFHQGAEGWWARSVGGSEHPPQWSPNGVLLSPEDEE--------ELTAPEKFLGDQRFS 553
Query: 1532 YGG--YLTYQAKSFGLPGDMVLLEKKPDVQLTGQHMSIIYEETNTPRPDRLHHGRVHVVE 1589
YG LT++ PGD L ++L G +++ ++ P H R +
Sbjct: 554 YGQPLILTFRVP----PGDSPL---PVQLRLEGTGLALSLRHSSLSGPQDAGHPREVELR 606
Query: 1590 GNFRHASS--RAPVSREELMTVLSRLADVRIQ--------GLYFTETQRLTLSEVGLEEA 1639
+ + S P+ +L+ L +R++ G F RLT + GL
Sbjct: 607 FHLQETSEDVAPPLPPFHFQRLLANLTSLRLRVSPGPSPAGPVFLTEVRLTSARPGLSPP 666
Query: 1640 SDTGSGRIALAVEICACPPAYAGDSCQGCSPGYYRD-HKGLYTGRCVPCNCNGHSNQCQD 1698
A VEIC+CP Y G C+ C+PGY R+ +G CVPC CN H C
Sbjct: 667 --------ASWVEICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT-CDP 717
Query: 1699 GSGICVNCQHNTAGEHCERCQEGYYGNAVHG---SCRACPCPHTNSFATGCVVNGGDVRC 1755
+GICV C H+T G CERC G+YGN G C+ CPCP ++ T + +V C
Sbjct: 718 NTGICV-CSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTT--IPESREVVC 774
Query: 1756 S-CKAGYTGTQCERCAPGYFGNPQKFGGSCQP---CSCNSN---GQLGSCHPLTGDCINQ 1808
+ C G G +CE C G+FG+P G QP C C+ N +G+C PL+G C+
Sbjct: 775 THCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCL-- 832
Query: 1809 EPKDSSPAEECDDC 1822
++ + C+ C
Sbjct: 833 RCLHNTTGDHCEHC 846
Score = 261 bits (667), Expect = 8e-69
Identities = 165/532 (31%), Positives = 239/532 (44%), Gaps = 73/532 (13%)
Query: 21 LLLLVLRVLPACGATARDPGAAAGLSLHPTYFNLAEAARIWATATCGERGPGEGRPQPEL 80
L LL R A G A GA P + N A A+ TCG PE
Sbjct: 10 LALLAPRAAGA-GMGACYDGAGRPQRCLPVFENAAFGRLAQASHTCGS--------PPED 60
Query: 81 YCKLVGGPTAPGSGHTIQGQFCDYCNSEDPRKAHPVTNAID----GSERWWQSPPLSSGT 136
+C VG A G C C++ DP++ H + D WWQSP ++ G
Sbjct: 61 FCPHVGAAGA--------GAHCQRCDAADPQRHHNASYLTDFHSQDESTWWQSPSMAFGV 112
Query: 137 QY-NRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVDFGSTYSPWQYFAHSKVDCL 195
QY VN+TL LG+ + + Y+ +KF S RP+ + + + + P+Q+++ S C
Sbjct: 113 QYPTSVNITLRLGKAYEITYVRLKFHTS-RPESFAIYKRSRADGPWEPYQFYSAS---CQ 168
Query: 196 KEFGREANMAVTRDDD---VLCVTEYSRIVPLENGEVVVSLINGRPGAKNFTFSHTLREF 252
K +GR + +D C +E+S I PL G V S + GRP A NF S L+E+
Sbjct: 169 KTYGRPEGQYLRPGEDERVAFCTSEFSDISPLSGGNVAFSTLEGRPSAYNFEESPGLQEW 228
Query: 253 TKATNIRLRFLRTNTLLGHLISKAQRDPTVTRRYYYSIKDISIGGQCVCNGHAEVCNINN 312
+T + + R NT + +DP V + YYY++ D S+GG+C CNGHA C +
Sbjct: 229 VTSTELLISLDRLNTFGDDIF----KDPKVLQSYYYAVSDFSVGGRCKCNGHASECGPDV 284
Query: 313 PEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVE 372
+L C CQH+T G C+RC + R W E +HEC CNC G + C +D ++
Sbjct: 285 AGQL-ACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELF 343
Query: 373 RQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEH 432
R GG C +C+ +TAG +CE+C + +Y D C PC C
Sbjct: 344 RSTGH---------GGRCHHCRDHTAGPHCERCQENFYH-----WDPRMPCQPCDCQSAG 389
Query: 433 ADGCE-QGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGC 491
+ + +G C CKP G C++C G+++ G + C
Sbjct: 390 SLHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLS-------------------EGGCRPC 430
Query: 492 DCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPI-----CQACWC 538
CN G L GRC C+ VEG CD CR G ++ C +C+C
Sbjct: 431 TCNPAGSLDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFC 482
Score = 168 bits (426), Expect = 7e-41
Identities = 109/361 (30%), Positives = 156/361 (43%), Gaps = 62/361 (17%)
Query: 392 NCQHNTAGVNCEQCAKGYYR--PYGVPVDAPDGCIPCSCDPEHADGCEQGSGRCHCKPNF 449
+C G CE CA GY R P G P + C+PC+C+ +H C+ +G C C +
Sbjct: 674 SCPTGYTGQFCESCAPGYKREMPQGGPYAS---CVPCTCN-QHGT-CDPNTGICVCSHHT 728
Query: 450 HGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRC 509
G +CE+C G+Y PF + A D + C C + I ++
Sbjct: 729 EGPSCERCLPGFYGNPFAGQ---------------ADDCQPCPCPGQSACTTIPESREVV 773
Query: 510 L--CRPGVEGPRCDTCRSGFYSFPI--------CQACWCS------ALGSYQMPCSSVTG 553
C PG G RC+ C GF+ P+ C C CS A+G+ C ++G
Sbjct: 774 CTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGN----CDPLSG 829
Query: 554 QC-ECRPGVTGQRCDRCLSGAYDF-----PHCQGSSSACDPAGTINSNL------GYCQC 601
C C TG C+ C G Y P + +C P G+++ + G C C
Sbjct: 830 HCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSC 889
Query: 602 KLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGD 661
HV CSRC +++L GC CKCH G S +C G C C+ V G
Sbjct: 890 LPHVTARDCSRCYPGFFDLQPGR--GCRSCKCHPLG--SQEDQCHPKTGQCTCRPGVTGQ 945
Query: 662 SCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENNY 721
+CD C+ G+F + GC+ C+C GA S+ C +G C CR G C R +N+
Sbjct: 946 ACDRCQLGFFGF---SIKGCRACRCSPLGAASAQCH-ENGTCVCRPGFEGYKCDRCHDNF 1001
Query: 722 Y 722
+
Sbjct: 1002 F 1002
Score = 165 bits (418), Expect = 6e-40
Identities = 115/386 (29%), Positives = 159/386 (41%), Gaps = 65/386 (16%)
Query: 319 CECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASL 378
C C G+ C+ C GY + + + C C C+ H + DP+
Sbjct: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYA---SCVPCTCNQHGT---CDPNT------- 719
Query: 379 NTQGIYAGGGVCINCQHNTAGVNCEQCAKGYY-RPYGVPVDAPDGCIPCSCDPEHADGCE 437
G+C+ C H+T G +CE+C G+Y P+ D C PC C + A
Sbjct: 720 ---------GICV-CSHHTEGPSCERCLPGFYGNPF---AGQADDCQPCPCPGQSACTTI 766
Query: 438 QGSGR---CHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCN 494
S HC P G CE C G++ P + +F P + +G++ D N
Sbjct: 767 PESREVVCTHCPPGQRGRRCEVCDDGFFGDP----LGLFGHPQPCHQCQCSGNV---DPN 819
Query: 495 LEGVLPEICD-AHGRCL-CRPGVEGPRCDTCRSGFYSFPI-------CQACWCSALGSY- 544
G CD G CL C G C+ C+ GFY + C C C GS
Sbjct: 820 AVG----NCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVS 875
Query: 545 -QMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSA-CDPAGT----INSNLGY 598
QMPC VTGQC C P VT + C RC G +D +G S C P G+ + G
Sbjct: 876 EQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQ 935
Query: 599 CQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHV 658
C C+ V G C RC+L ++ + GC C+C G S +C + +G C C+
Sbjct: 936 CTCRPGVTGQACDRCQLGFFGF---SIKGCRACRCSPLGAAS--AQCHE-NGTCVCRPGF 989
Query: 659 GGDSCDTCEDGYFALEKSNYFGCQGC 684
G CD C D +F + CQ C
Sbjct: 990 EGYKCDRCHDNFFLTADGTH--CQQC 1013
Score = 156 bits (395), Expect = 3e-37
Identities = 105/330 (31%), Positives = 136/330 (41%), Gaps = 54/330 (16%)
Query: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 358
C CN H C+ N C C HHT G +C+RC G+ + Q+ +C+ C C
Sbjct: 707 CTCNQHG-TCDPNTGI----CVCSHHTEGPSCERCLPGFYGNPFAG----QADDCQPCPC 757
Query: 359 HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYR-PYGVPV 417
G ++ C P+ VC +C G CE C G++ P G+
Sbjct: 758 PGQSA-CTTIPESREV--------------VCTHCPPGQRGRRCEVCDDGFFGDPLGL-F 801
Query: 418 DAPDGCIPCSC----DPEHADGCEQGSGRC-HCKPNFHGDNCEKCAIGYYNFPFCLRIPI 472
P C C C DP C+ SG C C N GD+CE C G+Y R
Sbjct: 802 GHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPR--- 858
Query: 473 FPVSTPSSEDPVAGDIKGCDCNLEGVLPEI--CD-AHGRCLCRPGVEGPRCDTCRSGFYS 529
A C C+ +G + E CD G+C C P V C C GF+
Sbjct: 859 -----------PADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFD 907
Query: 530 FPI---CQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSAC 586
C++C C LGS + C TGQC CRPGVTGQ CDRC G + F + C
Sbjct: 908 LQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRC 967
Query: 587 DPAGTINSNL---GYCQCKLHVEGPTCSRC 613
P G ++ G C C+ EG C RC
Sbjct: 968 SPLGAASAQCHENGTCVCRPGFEGYKCDRC 997
Score = 130 bits (328), Expect = 2e-29
Identities = 91/311 (29%), Positives = 120/311 (38%), Gaps = 59/311 (18%)
Query: 443 CHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGC---DCNLEGVL 499
C C + G CE CA GY E P G C CN G
Sbjct: 673 CSCPTGYTGQFCESCAPGY-----------------KREMPQGGPYASCVPCTCNQHGT- 714
Query: 500 PEICDAH-GRCLCRPGVEGPRCDTCRSGFYSFPI------CQACWCSALGSYQMPCSSVT 552
CD + G C+C EGP C+ C GFY P CQ C C Q C+++
Sbjct: 715 ---CDPNTGICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPG----QSACTTIP 767
Query: 553 GQCE-----CRPGVTGQRCDRCLSGAYDFP-----------HCQGSSSACDP--AGTINS 594
E C PG G+RC+ C G + P CQ S + DP G +
Sbjct: 768 ESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNV-DPNAVGNCDP 826
Query: 595 NLGYC-QCKLHVEGPTCSRCKLLYWN--LDKENPSGCSECKCHKAGTVSGTGECRQGDGD 651
G+C +C + G C C+ ++ L C C CH G+VS C G
Sbjct: 827 LSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQ 886
Query: 652 CHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVG 711
C C HV C C G+F L+ GC+ C+C G+ C +G C CR V G
Sbjct: 887 CSCLPHVTARDCSRCYPGFFDLQPGR--GCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTG 944
Query: 712 KVCQRPENNYY 722
+ C R + ++
Sbjct: 945 QACDRCQLGFF 955
Score = 127 bits (319), Expect = 2e-28
Identities = 71/216 (32%), Positives = 94/216 (43%), Gaps = 27/216 (12%)
Query: 1265 PC-ECHPTGATGPH----CSPEGGQC-PCQPNVIGRQCTRCATGHYGFP-------RCKP 1311
PC +C +G P+ C P G C C N G C C G YG +C P
Sbjct: 806 PCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMP 865
Query: 1312 CSCG-------RRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTI 1364
CSC + C+ +TGQC C P C C F P GC C C G+
Sbjct: 866 CSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQ 925
Query: 1365 EAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFP--ECVPCNCNRDGTEPGVCDPGTG 1422
E +C +GQC C+P +TG+ CDRC GF+ F C C C+ G C G
Sbjct: 926 E---DQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCHEN-G 981
Query: 1423 ACLCKENVEGTECNVCREGSF-HLDPANLKGCTSCF 1457
C+C+ EG +C+ C + F D + + C SC+
Sbjct: 982 TCVCRPGFEGYKCDRCHDNFFLTADGTHCQQCPSCY 1017
Score = 126 bits (317), Expect = 3e-28
Identities = 83/239 (34%), Positives = 106/239 (44%), Gaps = 41/239 (17%)
Query: 1260 HKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFP------RCKPCS 1313
+ +PC C+ G C P G C C + G C RC G YG P C+PC
Sbjct: 701 YASCVPCTCNQHGT----CDPNTGICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCP 756
Query: 1314 C-GRRLC----EEMTGQC-RCPPRTVRPQCEVCETHSFSF------HPMAGCEGCNCSRR 1361
C G+ C E C CPP +CEVC+ F HP C C CS
Sbjct: 757 CPGQSACTTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQP-CHQCQCS-- 813
Query: 1362 GTIEA-AMPECDRDSGQC-RCKPRITGRQCDRCASGFYRFP-------ECVPCNCNRDGT 1412
G ++ A+ CD SG C RC TG C+ C GFY +C+PC+C+ G+
Sbjct: 814 GNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGS 873
Query: 1413 --EPGVCDPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFCFGV---NNQCH 1466
E CDP TG C C +V +C+ C G F L P +GC SC C + +QCH
Sbjct: 874 VSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPG--RGCRSCKCHPLGSQEDQCH 930
Score = 124 bits (311), Expect = 2e-27
Identities = 74/221 (33%), Positives = 104/221 (47%), Gaps = 20/221 (9%)
Query: 426 CSCDPEHADGCEQ---GSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSED 482
C C+ HA C G C C+ N G +CE+C PF P + ++ +
Sbjct: 271 CKCNG-HASECGPDVAGQLACRCQHNTTGTDCERC------LPFFQDRPWARGTAEAAHE 323
Query: 483 PVAGDIKGC--DCNLEGVLPEICDAHGRCL-CRPGVEGPRCDTCRSGFYSFPI---CQAC 536
+ + G +C + L GRC CR GP C+ C+ FY + CQ C
Sbjct: 324 CLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPC 383
Query: 537 WCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINS-- 594
C + GS + C TG C C+P VTG +CDRCL G + C+PAG++++
Sbjct: 384 DCQSAGSLHLQCDD-TGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDTCD 442
Query: 595 -NLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCH 634
G C CK +VEG C RC+ +NL NP+GCS C C+
Sbjct: 443 PRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCY 483
Score = 119 bits (298), Expect = 5e-26
Identities = 72/233 (30%), Positives = 100/233 (42%), Gaps = 35/233 (15%)
Query: 1265 PCECHPTGATGPHCSPEGGQCPCQ---PNVIGRQCTRCATGHYGFPR--------CKPCS 1313
PC C G + PE + C P GR+C C G +G P C C
Sbjct: 754 PCPC--PGQSACTTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQ 811
Query: 1314 CGRRL-------CEEMTGQC-RCPPRTVRPQCEVCETHSFSF----HPMAGCEGCNCSRR 1361
C + C+ ++G C RC T CE C+ + P C C+C +
Sbjct: 812 CSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQ 871
Query: 1362 GTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPE---CVPCNCNRDGTEPGVCD 1418
G++ MP CD +GQC C P +T R C RC GF+ C C C+ G++ C
Sbjct: 872 GSVSEQMP-CDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCH 930
Query: 1419 PGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFCF---GVNNQCHSS 1468
P TG C C+ V G C+ C+ G F ++KGC +C C + QCH +
Sbjct: 931 PKTGQCTCRPGVTGQACDRCQLGFFGF---SIKGCRACRCSPLGAASAQCHEN 980
Score = 115 bits (288), Expect = 7e-25
Identities = 62/179 (34%), Positives = 83/179 (46%), Gaps = 17/179 (9%)
Query: 1656 CPPAYAGDSCQGCSPGYYRDHKGLY--TGRCVPCNCNGHSN-----QCQDGSGICVNCQH 1708
CPP G C+ C G++ D GL+ C C C+G+ + C SG C+ C H
Sbjct: 777 CPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLH 836
Query: 1709 NTAGEHCERCQEGYYGNAV----HGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGT 1764
NT G+HCE CQEG+YG+A+ C C C S + + +CSC T
Sbjct: 837 NTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTAR 896
Query: 1765 QCERCAPGYFGNPQKFGGSCQPCSCNSNG-QLGSCHPLTGDCINQEPKDSSPAEECDDC 1822
C RC PG+F + G C+ C C+ G Q CHP TG C + + CD C
Sbjct: 897 DCSRCYPGFF--DLQPGRGCRSCKCHPLGSQEDQCHPKTGQC---TCRPGVTGQACDRC 950
Score = 103 bits (258), Expect = 2e-21
Identities = 53/152 (34%), Positives = 69/152 (45%), Gaps = 15/152 (9%)
Query: 1264 LPCECHPTGATGPH--CSPEGGQCPCQPNVIGRQCTRCATGHYGFPR---CKPCSCG--- 1315
+PC CHP G+ C P GQC C P+V R C+RC G + C+ C C
Sbjct: 864 MPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLG 923
Query: 1316 --RRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDR 1373
C TGQC C P C+ C+ F F + GC C CS G AA +C
Sbjct: 924 SQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFS-IKGCRACRCSPLG---AASAQC-H 978
Query: 1374 DSGQCRCKPRITGRQCDRCASGFYRFPECVPC 1405
++G C C+P G +CDRC F+ + C
Sbjct: 979 ENGTCVCRPGFEGYKCDRCHDNFFLTADGTHC 1010
Score = 100 bits (248), Expect = 3e-20
Identities = 142/676 (21%), Positives = 249/676 (36%), Gaps = 109/676 (16%)
Query: 1662 GDSCQGCSPGYYRDHKGLYTG-RCVPCNCNGHSN-----QCQDGSGICVNCQHNTAGEHC 1715
GD C+ C G+Y +C+PC+C+ + C +G C H TA + C
Sbjct: 840 GDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARD-C 898
Query: 1716 ERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFG 1775
RC G++ CR+C C S C G +C+C+ G TG C+RC G+FG
Sbjct: 899 SRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTG--QCTCRPGVTGQACDRCQLGFFG 956
Query: 1776 NPQKFGGSCQPCSCNSNGQLGS-CHPLTGDCINQEPKDSSPAEECDD------------- 1821
K C+ C C+ G + CH G C+ + + + C D
Sbjct: 957 FSIK---GCRACRCSPLGAASAQCHE-NGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQ 1012
Query: 1822 CDSCVMTLLNDLATMGEQLRLVKSQLQGL-----------------------------SA 1852
C SC + + A + +L L + LQG A
Sbjct: 1013 CPSCYALVKEEAAKLKARLTLTEGWLQGSDCGSPWGPLDILLGEAPRGDVYQGHHLLPGA 1072
Query: 1853 SAGLLEQMRHMETQAKDLRNQL--LNYRSAISNHGSKIEGLERELTDLNQEFETLQEKAQ 1910
LEQM +E K R QL LN + + GS + +L DL E+ +E+
Sbjct: 1073 REAFLEQMMSLEGAVKAAREQLQRLNKGARCAQAGS--QKTCTQLADLEAVLESSEEEIL 1130
Query: 1911 VNSRKAQTLNNNVNRATQSAK--ELDVKIKNVIRNVHILLKQISGTDGEGNNVPSGDFSR 1968
+ +L +Q K L + + + R+ +I+ T + ++
Sbjct: 1131 HAAAILASLEIPQEGPSQPTKWSHLATEARALARSHRDTATKIAATAWRALLASNTSYAL 1190
Query: 1969 EWAEAQRMMRELRNRNFGKHLREAEADKRESQLLLNRI--------RTWQKTHQGENNGL 2020
W + + R+ +E +A ++ + + + T Q+ L
Sbjct: 1191 LWNLLEGRVALETQRDLEDRYQEVQAAQKALRTAVAEVLPEAESVLATVQQVGADTAPYL 1250
Query: 2021 ANSIRDSLNEYEAKLSDL----RARLQEAAAQAKQANGLNQENERALGAIQRQVKEINSL 2076
A +++ DL +A + A+ A + + A A RQ + + L
Sbjct: 1251 ALLASPGALPQKSRAEDLGLKAKALEKTVASWQHMATEAARTLQTAAQATLRQTEPLTKL 1310
Query: 2077 QSDFTKYLTTADSSLLQTNIALQLME---------KSQKEYEKLAASLNEARQELSDKVR 2127
+ LT A SS+ + + K Q K A+L +SD++
Sbjct: 1311 HQEARAALTQASSSVQAATVTVMGARTLLADLEGMKLQFPRPKDQAALQRKADSVSDRL- 1369
Query: 2128 ELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIK 2187
L+ + KT E +A L AK+ G E A D+A + +L K
Sbjct: 1370 -LADTRKKTKQAERMLGNAAPLSSSAKK--------KGREAEVLAKDSAKLAKALLRERK 1420
Query: 2188 AAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNN 2247
A A+R S +++ LQ ++ L +EA+ + + + V L+
Sbjct: 1421 QAHRRASRLTSQTQATLQ--------------QASQQVLASEARRQELEEAERVGAGLSE 1466
Query: 2248 LQQTL--NIVTVQKEV 2261
++Q + + ++++K++
Sbjct: 1467 MEQQIRESRISLEKDI 1482
Score = 98.2 bits (243), Expect = 1e-19
Identities = 68/208 (32%), Positives = 96/208 (46%), Gaps = 32/208 (15%)
Query: 530 FPICQACWCSALGSYQMPCSSVTGQ--CECRPGVTGQRCDRCLSGAYDFPHCQGSSSA-- 585
F + C C+ S P V GQ C C+ TG C+RCL D P +G++ A
Sbjct: 265 FSVGGRCKCNGHASECGP--DVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAH 322
Query: 586 ----CDPAG-----TINSNL-------GYC-QCKLHVEGPTCSRCKLLYWNLDKENPSGC 628
C+ +G T + L G C C+ H GP C RC+ +++ D P C
Sbjct: 323 ECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMP--C 380
Query: 629 SECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDI 688
C C AG++ +C G C CK V G CD C G+ +L + GC+ C C+
Sbjct: 381 QPCDCQSAGSLH--LQC-DDTGTCACKPTVTGWKCDRCLPGFHSLSEG---GCRPCTCNP 434
Query: 689 GGALSSMCSGPSGVCQCREHVVGKVCQR 716
G+L + C SG C C+E+V G +C R
Sbjct: 435 AGSLDT-CDPRSGRCPCKENVEGNLCDR 461
Score = 87.0 bits (214), Expect = 3e-16
Identities = 56/199 (28%), Positives = 77/199 (38%), Gaps = 27/199 (13%)
Query: 509 CLCRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQC------------- 555
C C+ G C+ C F P + +A CS + +C
Sbjct: 290 CRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHG 349
Query: 556 ----ECRPGVTGQRCDRCLSGAYDF-PHCQGSSSACDPAGTIN---SNLGYCQCKLHVEG 607
CR G C+RC Y + P C AG+++ + G C CK V G
Sbjct: 350 GRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQSAGSLHLQCDDTGTCACKPTVTG 409
Query: 608 PTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCE 667
C RC + +L + GC C C+ AG++ C G C CK +V G+ CD C
Sbjct: 410 WKCDRCLPGFHSLSE---GGCRPCTCNPAGSLD---TCDPRSGRCPCKENVEGNLCDRCR 463
Query: 668 DGYFALEKSNYFGCQGCQC 686
G F L+ N GC C C
Sbjct: 464 PGTFNLQPHNPAGCSSCFC 482
Score = 82.4 bits (202), Expect = 7e-15
Identities = 55/189 (29%), Positives = 74/189 (39%), Gaps = 15/189 (7%)
Query: 547 PCSSVTGQCECRPGVTGQRCDRCLSG-----AYDFPHCQGSSSACDPAGTINSNLGYCQC 601
P +S C C G TGQ C+ C G P+ C+ GT + N G C C
Sbjct: 665 PPASWVEICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGTCDPNTGICVC 724
Query: 602 KLHVEGPTCSRC-KLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGG 660
H EGP+C RC Y N C C C + E R+ HC G
Sbjct: 725 SHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESRE-VVCTHCPPGQRG 783
Query: 661 DSCDTCEDGYFALEKSNYFG----CQGCQC--DIGGALSSMCSGPSGVC-QCREHVVGKV 713
C+ C+DG+F + FG C CQC ++ C SG C +C + G
Sbjct: 784 RRCEVCDDGFFG-DPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDH 842
Query: 714 CQRPENNYY 722
C+ + +Y
Sbjct: 843 CEHCQEGFY 851
Score = 74.3 bits (181), Expect = 2e-12
Identities = 35/103 (33%), Positives = 46/103 (44%), Gaps = 8/103 (7%)
Query: 1261 KGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFP-------RCKPCS 1313
+G C+CHP G+ C P+ GQC C+P V G+ C RC G +GF RC P
Sbjct: 912 RGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCSPLG 971
Query: 1314 CGRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGC 1356
C E G C C P +C+ C + F C+ C
Sbjct: 972 AASAQCHE-NGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQC 1013
Score = 54.3 bits (129), Expect = 2e-06
Identities = 22/58 (37%), Positives = 27/58 (46%), Gaps = 1/58 (1%)
Query: 1262 GALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCGRRLC 1319
G PC C+P G+ C P G+CPC+ NV G C RC G + P C C
Sbjct: 426 GCRPCTCNPAGSLDT-CDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFC 482
Score = 43.9 bits (102), Expect = 0.003
Identities = 26/85 (30%), Positives = 32/85 (37%), Gaps = 5/85 (5%)
Query: 1241 PQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCA 1300
P + C F KG C C P GA C E G C C+P G +C RC
Sbjct: 940 PGVTGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCH-ENGTCVCRPGFEGYKCDRCH 998
Query: 1301 TGHY---GFPRCKPC-SCGRRLCEE 1321
+ C+ C SC + EE
Sbjct: 999 DNFFLTADGTHCQQCPSCYALVKEE 1023
Score = 43.5 bits (101), Expect = 0.003
Identities = 31/95 (32%), Positives = 42/95 (44%), Gaps = 19/95 (20%)
Query: 280 PTVTR----RYYYSIKDISIGG--QCVCN--GHAEVCNINNPEKLFRCECQHHTCGETCD 331
PTVT R +S GG C CN G + C+ + RC C+ + G CD
Sbjct: 405 PTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDTCDPRSG----RCPCKENVEGNLCD 460
Query: 332 RCCTG-YNQRRWRPAAWEQSHECEACNCHGHASNC 365
RC G +N + PA C +C C+GH+ C
Sbjct: 461 RCRPGTFNLQPHNPAG------CSSCFCYGHSKVC 489
Score = 38.5 bits (88), Expect = 0.11
Identities = 31/110 (28%), Positives = 43/110 (39%), Gaps = 20/110 (18%)
Query: 631 CKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTC----EDGYFALEKSNY-FGCQGCQ 685
CKC+ G S G G C C+ + G C+ C +D +A + C C
Sbjct: 271 CKCN--GHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCN 328
Query: 686 CDIGGALSSMCS---------GPSGVCQ-CREHVVGKVCQRPENNYYFPD 725
C S C+ G G C CR+H G C+R + N+Y D
Sbjct: 329 CS---GRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWD 375
>gi|145309326 laminin, gamma 1 precursor [Homo sapiens]
Length = 1609
Score = 285 bits (728), Expect = 7e-76
Identities = 179/566 (31%), Positives = 257/566 (45%), Gaps = 78/566 (13%)
Query: 2 AAAARPRGRALGPVLPPTPLLLLVLRVLPACGATARDPGAAAG---LSLHPTYFNLAEAA 58
A A RPRGR L PVL +L C A D G P + N A
Sbjct: 8 APALRPRGR-LWPVLA-----VLAAAAAAGCAQAAMDECTDEGGRPQRCMPEFVNAAFNV 61
Query: 59 RIWATATCGERGPGEGRPQPELYCKLVGGPTAPGSGHTIQGQFCDYCNSEDPRKAHPVTN 118
+ AT TCG PE YC G S C C++ P H
Sbjct: 62 TVVATNTCGT--------PPEEYCVQTGVTGVTKS--------CHLCDAGQPHLQHGAAF 105
Query: 119 AIDGSER----WWQSPPLSSGTQY-NRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLER 173
D + + WWQS + +G QY + +NLTL LG+ F + Y+ +KF S RP+ + + +
Sbjct: 106 LTDYNNQADTTWWQSQTMLAGVQYPSSINLTLHLGKAFDITYVRLKFHTS-RPESFAIYK 164
Query: 174 SVDFGSTYSPWQYFAHSKVDCLKEFGREANMAVTRDDDVLCVTEYSRIVPLENGEVVVSL 233
+ P+QY++ S + + R + LC E+S I PL G V S
Sbjct: 165 RTREDGPWIPYQYYSGSCENTYSKANRGFIRTGGDEQQALCTDEFSDISPLTGGNVAFST 224
Query: 234 INGRPGAKNFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDPTVTRRYYYSIKDI 293
+ GRP A NF S L+E+ AT+IR+ R NT + + DP V + YYY+I D
Sbjct: 225 LEGRPSAYNFDNSPVLQEWVTATDIRVTLNRLNTFGDEVFN----DPKVLKSYYYAISDF 280
Query: 294 SIGGQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHEC 353
++GG+C CNGHA C N +KL C C+H+T G C++C +N R WR A E + EC
Sbjct: 281 AVGGRCKCNGHASECMKNEFDKLV-CNCKHNTYGVDCEKCLPFFNDRPWRRATAESASEC 339
Query: 354 EACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPY 413
C+C+G + CY+DP++ R GG C NCQ NT G +CE+C + ++R
Sbjct: 340 LPCDCNGRSQECYFDPELYRSTGH---------GGHCTNCQDNTDGAHCERCRENFFR-- 388
Query: 414 GVPVDAPDGCIPCSCDPEHADGCEQGS-GRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPI 472
+ + C C C P + + S GRC CKP GD C++C G+++
Sbjct: 389 ---LGNNEACSSCHCSPVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSL-------- 437
Query: 473 FPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPI 532
+ C C+ G + E GRC+C+ VEG C+ C+ GF++
Sbjct: 438 -----------TEAGCRPCSCDPSGSIDECNIETGRCVCKDNVEGFNCERCKPGFFNLES 486
Query: 533 -----CQACWCSALGSYQMPCSSVTG 553
C C+C S C++ G
Sbjct: 487 SNPRGCTPCFCFGHSSV---CTNAVG 509
Score = 280 bits (717), Expect = 1e-74
Identities = 193/605 (31%), Positives = 276/605 (45%), Gaps = 90/605 (14%)
Query: 1285 CPCQPNVIGRQCTRCATGHYGFP----------RCKPCSCGRRLCE-----------EMT 1323
C C+ N G C +C P C PC C R E
Sbjct: 305 CNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRSTGHG 364
Query: 1324 GQC-RCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKP 1382
G C C T CE C + F C C+CS G++ +CD G+C CKP
Sbjct: 365 GHCTNCQDNTDGAHCERCRENFFRLGNNEACSSCHCSPVGSLST---QCD-SYGRCSCKP 420
Query: 1383 RITGRQCDRCASGFYRFPE--CVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCRE 1440
+ G +CDRC GF+ E C PC+C+ G+ C+ TG C+CK+NVEG C C+
Sbjct: 421 GVMGDKCDRCQPGFHSLTEAGCRPCSCDPSGSIDE-CNIETGRCVCKDNVEGFNCERCKP 479
Query: 1441 GSFHLDPANLKGCTSCFCFGVNNQC-----HSSHKRRTKF-VDMLGWHLETADRVDIPVS 1494
G F+L+ +N +GCT CFCFG ++ C +S + + F +D GW E D + +
Sbjct: 480 GFFNLESSNPRGCTPCFCFGHSSVCTNAVGYSVYSISSTFQIDEDGWRAEQRDGSEASLE 539
Query: 1495 FNPGSNSMVADLQELPATIHSASWVAPTSYLGDKVSSYGGYLTY----QAKSFGLPGDMV 1550
+ +S D+ + + ++AP +LG +V SYG L++ + L + +
Sbjct: 540 W----SSERQDIAVISDSYFPRYFIAPAKFLGKQVLSYGQNLSFSFRVDRRDTRLSAEDL 595
Query: 1551 LLE---KKPDVQLTGQHMSIIYEETNTPRPDRLHHGRVHVVEGNFRHASSRAPVSREELM 1607
+LE + V L Q S ET RLH + R ++ E
Sbjct: 596 VLEGAGLRVSVPLIAQGNS-YPSETTVKYVFRLHEATDY---------PWRPALTPFEFQ 645
Query: 1608 TVLSRLADVRIQGLYFTETQRLTLSEVGLEEASDTGSGRIALAVEICACPPAYAGDSCQG 1667
+L+ L ++I+G Y +E L +V L A G G A VE C CP Y G C+
Sbjct: 646 KLLNNLTSIKIRGTY-SERSAGYLDDVTLASAR-PGPGVPATWVESCTCPVGYGGQFCEM 703
Query: 1668 CSPGYYRDHKGLYT-GRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNA 1726
C GY R+ L CV C CNGHS C +G+C NC+ NTAG HCE+C +GYYG++
Sbjct: 704 CLSGYRRETPNLGPYSPCVLCACNGHSETCDPETGVC-NCRDNTAGPHCEKCSDGYYGDS 762
Query: 1727 VHGS---CRACPCPHTNSFATGCVVNGGDVRC-SCKAGYTGTQCERCAPGYFGNPQKFGG 1782
G+ C+ CPCP +S A V +V C +C G TG +CE C GYFG+P G
Sbjct: 763 TAGTSSDCQPCPCPGGSSCAV--VPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNG 820
Query: 1783 S---CQPCSCNSN---GQLGSCHPLTGDCIN------------------QEPKDSSPAEE 1818
C+ C C+ N +G+C+ LTG+C+ P +PA++
Sbjct: 821 PVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADK 880
Query: 1819 CDDCD 1823
C C+
Sbjct: 881 CKACN 885
Score = 175 bits (443), Expect = 8e-43
Identities = 121/384 (31%), Positives = 165/384 (42%), Gaps = 60/384 (15%)
Query: 319 CECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASL 378
C C G+ C+ C +GY RR P S C C C+GH+ C DP+
Sbjct: 690 CTCPVGYGGQFCEMCLSGY--RRETPNLGPYS-PCVLCACNGHSETC--DPET------- 737
Query: 379 NTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADGCEQ 438
GVC NC+ NTAG +CE+C+ GYY + C PC C +
Sbjct: 738 ---------GVC-NCRDNTAGPHCEKCSDGYYGDSTAGTSSD--CQPCPCPGGSSCAVVP 785
Query: 439 GSGRC---HCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNL 495
+ +C G CE C GY+ P P+ D + + G +CN
Sbjct: 786 KTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVG-NCNR 844
Query: 496 EGVLPEICDAHGRCL-CRPGVEGPRCDTCRSGFYSFPI-------CQACWCSALGSY--Q 545
G CL C G CD C+ GF+ P+ C+AC C+ G+ Q
Sbjct: 845 ---------LTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACNCNLYGTMKQQ 895
Query: 546 MPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSA-CDPAGTINSNL----GYCQ 600
C+ VTGQCEC P VTGQ C C G Y+ QG C G+ N G C+
Sbjct: 896 SSCNPVTGQCECLPHVTGQDCGACDPGFYNLQSGQGCERCDCHALGSTNGQCDIRTGQCE 955
Query: 601 CKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGG 660
C+ + G C RC++ ++ P GC C CH G++S +C+ DG C C+ G
Sbjct: 956 CQPGITGQHCERCEVNHFGF---GPEGCKPCDCHPEGSLSL--QCKD-DGRCECREGFVG 1009
Query: 661 DSCDTCEDGYFALEKSNYFGCQGC 684
+ CD CE+ YF ++ GCQ C
Sbjct: 1010 NRCDQCEENYF--YNRSWPGCQEC 1031
Score = 166 bits (420), Expect = 4e-40
Identities = 109/362 (30%), Positives = 158/362 (43%), Gaps = 63/362 (17%)
Query: 393 CQHNTAGVNCEQCAKGYYRPYGVPVDAP-DGCIPCSCDPEHADGCEQGSGRCHCKPNFHG 451
C G CE C GY R P P C+ C+C+ H++ C+ +G C+C+ N G
Sbjct: 692 CPVGYGGQFCEMCLSGYRRE--TPNLGPYSPCVLCACNG-HSETCDPETGVCNCRDNTAG 748
Query: 452 DNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDC---NLEGVLPEICDAHGR 508
+CEKC+ GYY S + D + C C + V+P+ +
Sbjct: 749 PHCEKCSDGYYG---------------DSTAGTSSDCQPCPCPGGSSCAVVPKTKEVV-- 791
Query: 509 CL-CRPGVEGPRCDTCRSGFYSFPI--------CQACWCS------ALGSYQMPCSSVTG 553
C C G G RC+ C G++ P+ C+ C CS A+G+ C+ +TG
Sbjct: 792 CTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGN----CNRLTG 847
Query: 554 QC-ECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPA-----GTI------NSNLGYCQC 601
+C +C G CDRC G + P + C GT+ N G C+C
Sbjct: 848 ECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACNCNLYGTMKQQSSCNPVTGQCEC 907
Query: 602 KLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGD 661
HV G C C ++NL ++ GC C CH G+ +G +C G C C+ + G
Sbjct: 908 LPHVTGQDCGACDPGFYNL--QSGQGCERCDCHALGSTNG--QCDIRTGQCECQPGITGQ 963
Query: 662 SCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENNY 721
C+ CE +F GC+ C C G+LS C G C+CRE VG C + E NY
Sbjct: 964 HCERCEVNHFGFGPE---GCKPCDCHPEGSLSLQCKD-DGRCECREGFVGNRCDQCEENY 1019
Query: 722 YF 723
++
Sbjct: 1020 FY 1021
Score = 165 bits (418), Expect = 6e-40
Identities = 111/350 (31%), Positives = 152/350 (43%), Gaps = 59/350 (16%)
Query: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 358
C CNGH+E C+ PE C C+ +T G C++C GY + + S +C+ C C
Sbjct: 724 CACNGHSETCD---PETGV-CNCRDNTAGPHCEKCSDGY----YGDSTAGTSSDCQPCPC 775
Query: 359 HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYR-PYGV-- 415
G S+C P + VC NC T G CE C GY+ P G
Sbjct: 776 PG-GSSCAVVPKTKEV--------------VCTNCPTGTTGKRCELCDDGYFGDPLGRNG 820
Query: 416 PVDAPDGCIPCSC----DPEHADGCEQGSGRC-HCKPNFHGDNCEKCAIGYYNFPFCLRI 470
PV C C C DP C + +G C C N G C++C G++ P
Sbjct: 821 PVRL---CRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLA--- 874
Query: 471 PIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAH---GRCLCRPGVEGPRCDTCRSGF 527
P+ D K C+CNL G + + + G+C C P V G C C GF
Sbjct: 875 -------PNPADKC----KACNCNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGF 923
Query: 528 YSFPI---CQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSS 584
Y+ C+ C C ALGS C TGQCEC+PG+TGQ C+RC + F
Sbjct: 924 YNLQSGQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHFGFGPEGCKPC 983
Query: 585 ACDPAGTIN---SNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSEC 631
C P G+++ + G C+C+ G C +C+ Y+ + GC EC
Sbjct: 984 DCHPEGSLSLQCKDDGRCECREGFVGNRCDQCEENYFY--NRSWPGCQEC 1031
Score = 138 bits (347), Expect = 1e-31
Identities = 173/759 (22%), Positives = 312/759 (41%), Gaps = 102/759 (13%)
Query: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSN-QCQDGSGICVNCQHNTAG 1712
C C P G C C PG+Y G RC C+ G +N QC +G C CQ G
Sbjct: 905 CECLPHVTGQDCGACDPGFYNLQSGQGCERC-DCHALGSTNGQCDIRTGQC-ECQPGITG 962
Query: 1713 EHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPG 1772
+HCERC+ ++G G C+ C C S + C +G RC C+ G+ G +C++C
Sbjct: 963 QHCERCEVNHFGFGPEG-CKPCDCHPEGSLSLQCKDDG---RCECREGFVGNRCDQCEEN 1018
Query: 1773 YFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMTLLND 1832
YF N G CQ C +C+ L D K + + + +S + L
Sbjct: 1019 YFYNRSWPG--CQECP--------ACYRLVKD------KVADHRVKLQELESLIANLGTG 1062
Query: 1833 LATMGEQL---RLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIE 1889
+ +Q RL +++ + + LL + + ++ ++L ++L + +S+ S+++
Sbjct: 1063 DEMVTDQAFEDRLKEAEREVMD----LLREAQDVKDVDQNLMDRLQRVNNTLSSQISRLQ 1118
Query: 1890 GLERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHILLK 1949
+ + +E L E+A+ + + L +R + AK + ++ +
Sbjct: 1119 NIRNTI----EETGNLAEQARAHVENTERLIEIASRELEKAK---------VAAANVSVT 1165
Query: 1950 QISGTDGEGNNVPSGDFSREWAEAQRMMRELRNRNFGKHLREAEADKRESQLLLNRIRTW 2009
Q T G+ NN+ AE R + E + +R A+ S N +
Sbjct: 1166 QPEST-GDPNNMTL------LAEEARKLAERHKQEADDIVRVAKTANDTSTEAYNLL--- 1215
Query: 2010 QKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERA---LGAI 2066
+T GEN A I + +YE + ++ L+ KQA +++E +RA I
Sbjct: 1216 LRTLAGENQ-TAFEIEELNRKYE-QAKNISQDLE------KQAARVHEEAKRAGDKAVEI 1267
Query: 2067 QRQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKV 2126
V +++ L S+ + A++ ++ QL+++ K+YE L + E+ + +
Sbjct: 1268 YASVAQLSPLDSETLE--NEANNIKMEAENLEQLIDQKLKDYEDLREDMRGKELEVKNLL 1325
Query: 2127 RE-----------LSRSAGKTSLVEEAEKHAR-SLQELAKQLEEIKRNASGDELVRCAVD 2174
+ L+R+ +L EEA K R +LQE L +K + R D
Sbjct: 1326 EKGKTEQQTADQLLARADAAKALAEEAAKKGRDTLQEANDILNNLK------DFDRRVND 1379
Query: 2175 AATAYENILNAIKA-----------AEDAANRAASASESALQTVIK-EDLPRKAKTLSSN 2222
TA E L I A +A SA+ A + K + R A + N
Sbjct: 1380 NKTAAEEALRKIPAINQTITEANEKTREAQQALGSAAADATEAKNKAHEAERIASAVQKN 1439
Query: 2223 SDKLLNEAKMTQKK---LKQEVSPALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRG 2279
+ EA+ T + L EV+ L LQ+ + +++ D ++ Q
Sbjct: 1440 ATSTKAEAERTFAEVTDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEA 1499
Query: 2280 DIDAMISSAKSMVRKANDITDEVLDGLNPIQT-DVERIKDTYGRTQNEDFKKALTDADNS 2338
+I+A AK+ V I +++L+ L + T D+ ++ + G + ++D D
Sbjct: 1500 EINA--RKAKNSVTSLLSIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMKVSDLDRK 1557
Query: 2339 VNKLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELI 2377
V+ L N+ I N+ + + N++ IR+ +
Sbjct: 1558 VSDLENEAKKQEAAIMDYNRDIEEIMKDIRNLEDIRKTL 1596
Score = 130 bits (328), Expect = 2e-29
Identities = 82/245 (33%), Positives = 113/245 (46%), Gaps = 24/245 (9%)
Query: 401 NCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADGCEQGSGR---CHCKPNFHGDNCEKC 457
N + K YY Y + A G C C+ HA C + C+CK N +G +CEKC
Sbjct: 265 NDPKVLKSYY--YAISDFAVGG--RCKCNG-HASECMKNEFDKLVCNCKHNTYGVDCEKC 319
Query: 458 AIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGC--DCNLEGVLPEICDAHGRCL-CRPG 514
PF P + S+ + + D G +C + L G C C+
Sbjct: 320 ------LPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRSTGHGGHCTNCQDN 373
Query: 515 VEGPRCDTCRSGFYSF---PICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLS 571
+G C+ CR F+ C +C CS +GS C S G+C C+PGV G +CDRC
Sbjct: 374 TDGAHCERCRENFFRLGNNEACSSCHCSPVGSLSTQCDSY-GRCSCKPGVMGDKCDRCQP 432
Query: 572 GAYDFPHCQGSSSACDPAGTI---NSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGC 628
G + +CDP+G+I N G C CK +VEG C RCK ++NL+ NP GC
Sbjct: 433 GFHSLTEAGCRPCSCDPSGSIDECNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGC 492
Query: 629 SECKC 633
+ C C
Sbjct: 493 TPCFC 497
Score = 128 bits (321), Expect = 1e-28
Identities = 88/304 (28%), Positives = 118/304 (38%), Gaps = 44/304 (14%)
Query: 443 CHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEI 502
C C + G CE C GY E P G C E
Sbjct: 690 CTCPVGYGGQFCEMCLSGYRR-----------------ETPNLGPYSPCVLCACNGHSET 732
Query: 503 CDAH-GRCLCRPGVEGPRCDTCRSGFYSFPI------CQACWCSALGSYQMPCSSVTGQC 555
CD G C CR GP C+ C G+Y CQ C C S + + C
Sbjct: 733 CDPETGVCNCRDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKEVVC 792
Query: 556 -ECRPGVTGQRCDRCLSGAYDFPH-----------CQGSSSACDP--AGTINSNLGYC-Q 600
C G TG+RC+ C G + P CQ S + DP G N G C +
Sbjct: 793 TNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNI-DPNAVGNCNRLTGECLK 851
Query: 601 CKLHVEGPTCSRCKL-LYWNLDKENPSG-CSECKCHKAGTVSGTGECRQGDGDCHCKSHV 658
C + G C RCK + N NP+ C C C+ GT+ C G C C HV
Sbjct: 852 CIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACNCNLYGTMKQQSSCNPVTGQCECLPHV 911
Query: 659 GGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPE 718
G C C+ G++ L+ GC+ C C G+ + C +G C+C+ + G+ C+R E
Sbjct: 912 TGQDCGACDPGFYNLQSGQ--GCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCE 969
Query: 719 NNYY 722
N++
Sbjct: 970 VNHF 973
Score = 124 bits (312), Expect = 1e-27
Identities = 75/245 (30%), Positives = 113/245 (46%), Gaps = 28/245 (11%)
Query: 1266 CECHPT---GATGPHCSPEGGQC-PCQPNVIGRQCTRCATGHYGFP-------RCKPCSC 1314
C+C A G +C+ G+C C N G C RC G +G P +CK C+C
Sbjct: 828 CQCSDNIDPNAVG-NCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACNC 886
Query: 1315 G-------RRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAA 1367
+ C +TGQC C P C C+ ++ GCE C+C G+
Sbjct: 887 NLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFYNLQSGQGCERCDCHALGSTNG- 945
Query: 1368 MPECDRDSGQCRCKPRITGRQCDRCASGFYRF-PE-CVPCNCNRDGTEPGVCDPGTGACL 1425
+CD +GQC C+P ITG+ C+RC + F PE C PC+C+ +G+ C G C
Sbjct: 946 --QCDIRTGQCECQPGITGQHCERCEVNHFGFGPEGCKPCDCHPEGSLSLQCKDD-GRCE 1002
Query: 1426 CKENVEGTECNVCREGSFHLDPANLKGCTSC-FCFGVNNQCHSSHKRRTKFVDMLGWHLE 1484
C+E G C+ C E F+ + GC C C+ + + H+ + + ++ L +L
Sbjct: 1003 CREGFVGNRCDQCEENYFY--NRSWPGCQECPACYRLVKDKVADHRVKLQELESLIANLG 1060
Query: 1485 TADRV 1489
T D +
Sbjct: 1061 TGDEM 1065
Score = 115 bits (287), Expect = 9e-25
Identities = 74/230 (32%), Positives = 100/230 (43%), Gaps = 36/230 (15%)
Query: 1266 CECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYG------FPRCKPCSC-GRRL 1318
C C+ T C PE G C C+ N G C +C+ G+YG C+PC C G
Sbjct: 724 CACNGHSET---CDPETGVCNCRDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSS 780
Query: 1319 CEEMTGQ-----CRCPPRTVRPQCEVCETHSFS-----FHPMAGCEGCNCSRRGTIEAAM 1368
C + CP T +CE+C+ F P+ C C CS A+
Sbjct: 781 CAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCS-DNIDPNAV 839
Query: 1369 PECDRDSGQC-RCKPRITGRQCDRCASGFYRFP-------ECVPCNCNRDGT--EPGVCD 1418
C+R +G+C +C G CDRC GF+ P +C CNCN GT + C+
Sbjct: 840 GNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACNCNLYGTMKQQSSCN 899
Query: 1419 PGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFCFGV---NNQC 1465
P TG C C +V G +C C G ++L +GC C C + N QC
Sbjct: 900 PVTGQCECLPHVTGQDCGACDPGFYNLQSG--QGCERCDCHALGSTNGQC 947
Score = 109 bits (272), Expect = 5e-23
Identities = 59/195 (30%), Positives = 85/195 (43%), Gaps = 27/195 (13%)
Query: 1287 CQPNVIGRQCTRCATGHYGFPR--------CKPCSCGRRL-------CEEMTGQC-RCPP 1330
C G++C C G++G P C+ C C + C +TG+C +C
Sbjct: 795 CPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIY 854
Query: 1331 RTVRPQCEVCETHSFSF----HPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITG 1386
T C+ C+ F +P C+ CNC+ GT++ C+ +GQC C P +TG
Sbjct: 855 NTAGFYCDRCKDGFFGNPLAPNPADKCKACNCNLYGTMKQ-QSSCNPVTGQCECLPHVTG 913
Query: 1387 RQCDRCASGFYRFPE---CVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCREGSF 1443
+ C C GFY C C+C+ G+ G CD TG C C+ + G C C F
Sbjct: 914 QDCGACDPGFYNLQSGQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHF 973
Query: 1444 HLDPANLKGCTSCFC 1458
P +GC C C
Sbjct: 974 GFGP---EGCKPCDC 985
Score = 97.8 bits (242), Expect = 2e-19
Identities = 50/154 (32%), Positives = 70/154 (45%), Gaps = 16/154 (10%)
Query: 1263 ALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPR---CKPCSC----- 1314
A C + T C+P GQC C P+V G+ C C G Y C+ C C
Sbjct: 883 ACNCNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFYNLQSGQGCERCDCHALGS 942
Query: 1315 GRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRD 1374
C+ TGQC C P CE CE + F F P GC+ C+C G++ +C +D
Sbjct: 943 TNGQCDIRTGQCECQPGITGQHCERCEVNHFGFGP-EGCKPCDCHPEGSLSL---QC-KD 997
Query: 1375 SGQCRCKPRITGRQCDRCASGFY---RFPECVPC 1405
G+C C+ G +CD+C ++ +P C C
Sbjct: 998 DGRCECREGFVGNRCDQCEENYFYNRSWPGCQEC 1031
Score = 94.4 bits (233), Expect = 2e-18
Identities = 61/214 (28%), Positives = 92/214 (42%), Gaps = 30/214 (14%)
Query: 509 CLCRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQC------------- 555
C C+ G C+ C F P +A SA C+ + +C
Sbjct: 305 CNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRSTGHG 364
Query: 556 ----ECRPGVTGQRCDRCLSGAYDFPHCQGSSSA-CDPAGTINS---NLGYCQCKLHVEG 607
C+ G C+RC + + + SS C P G++++ + G C CK V G
Sbjct: 365 GHCTNCQDNTDGAHCERCRENFFRLGNNEACSSCHCSPVGSLSTQCDSYGRCSCKPGVMG 424
Query: 608 PTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCE 667
C RC+ + +L + +GC C C +G++ EC G C CK +V G +C+ C+
Sbjct: 425 DKCDRCQPGFHSLTE---AGCRPCSCDPSGSID---ECNIETGRCVCKDNVEGFNCERCK 478
Query: 668 DGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSG 701
G+F LE SN GC C C SS+C+ G
Sbjct: 479 PGFFNLESSNPRGCTPCFC---FGHSSVCTNAVG 509
Score = 90.5 bits (223), Expect = 2e-17
Identities = 61/212 (28%), Positives = 94/212 (44%), Gaps = 28/212 (13%)
Query: 530 FPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFP------------ 577
F + C C+ S M C C+ G C++CL D P
Sbjct: 280 FAVGGRCKCNGHASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASEC 339
Query: 578 ---HCQGSSSAC--DPA-GTINSNLGYC-QCKLHVEGPTCSRCKLLYWNLDKENPSGCSE 630
C G S C DP + G+C C+ + +G C RC+ ++ L N CS
Sbjct: 340 LPCDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLG--NNEACSS 397
Query: 631 CKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGG 690
C C G++S +C G C CK V GD CD C+ G+ +L ++ GC+ C CD G
Sbjct: 398 CHCSPVGSLST--QC-DSYGRCSCKPGVMGDKCDRCQPGFHSLTEA---GCRPCSCDPSG 451
Query: 691 ALSSMCSGPSGVCQCREHVVGKVCQRPENNYY 722
++ C+ +G C C+++V G C+R + ++
Sbjct: 452 SIDE-CNIETGRCVCKDNVEGFNCERCKPGFF 482
Score = 80.5 bits (197), Expect = 3e-14
Identities = 37/103 (35%), Positives = 50/103 (48%), Gaps = 8/103 (7%)
Query: 1261 KGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGF--PRCKPCSCGRR- 1317
+G C+CH G+T C GQC CQP + G+ C RC H+GF CKPC C
Sbjct: 930 QGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHFGFGPEGCKPCDCHPEG 989
Query: 1318 ----LCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGC 1356
C++ G+C C V +C+ CE + F GC+ C
Sbjct: 990 SLSLQCKD-DGRCECREGFVGNRCDQCEENYFYNRSWPGCQEC 1031
Score = 79.3 bits (194), Expect = 6e-14
Identities = 53/198 (26%), Positives = 75/198 (37%), Gaps = 71/198 (35%)
Query: 1687 CNCNGHSNQCQDGS--GICVNCQHNTAGEHCERC-------------------------- 1718
C CNGH+++C + NC+HNT G CE+C
Sbjct: 286 CKCNGHASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCN 345
Query: 1719 ---QEGY-----YGNAVHGS----------------CR-------------ACPCPHTNS 1741
QE Y Y + HG CR +C C S
Sbjct: 346 GRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGNNEACSSCHCSPVGS 405
Query: 1742 FATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPL 1801
+T C G RCSCK G G +C+RC PG+ + C+PCSC+ +G + C+
Sbjct: 406 LSTQCDSYG---RCSCKPGVMGDKCDRCQPGFHSLTE---AGCRPCSCDPSGSIDECNIE 459
Query: 1802 TGDCINQEPKDSSPAEEC 1819
TG C+ ++ + E C
Sbjct: 460 TGRCVCKDNVEGFNCERC 477
Score = 62.8 bits (151), Expect = 6e-09
Identities = 33/101 (32%), Positives = 43/101 (42%), Gaps = 9/101 (8%)
Query: 1266 CECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPR--CKPCSCGRR----LC 1319
C C P G+ C G +C C+P V+G +C RC G + C+PCSC C
Sbjct: 398 CHCSPVGSLSTQCDSYG-RCSCKPGVMGDKCDRCQPGFHSLTEAGCRPCSCDPSGSIDEC 456
Query: 1320 EEMTGQCRCPPRTVRPQCEVCETHSFSFHPM--AGCEGCNC 1358
TG+C C CE C+ F+ GC C C
Sbjct: 457 NIETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFC 497
Score = 52.4 bits (124), Expect = 8e-06
Identities = 23/90 (25%), Positives = 41/90 (45%), Gaps = 4/90 (4%)
Query: 1241 PQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCA 1300
P + C+ + F +G PC+CHP G+ C + G+C C+ +G +C +C
Sbjct: 958 PGITGQHCERCEVNHFGFGPEGCKPCDCHPEGSLSLQCK-DDGRCECREGFVGNRCDQCE 1016
Query: 1301 TGHY---GFPRCKPCSCGRRLCEEMTGQCR 1327
++ +P C+ C RL ++ R
Sbjct: 1017 ENYFYNRSWPGCQECPACYRLVKDKVADHR 1046
Score = 49.3 bits (116), Expect = 6e-05
Identities = 24/58 (41%), Positives = 30/58 (51%), Gaps = 6/58 (10%)
Query: 1262 GALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGF----PR-CKPCSC 1314
G PC C P+G+ C+ E G+C C+ NV G C RC G + PR C PC C
Sbjct: 441 GCRPCSCDPSGSID-ECNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFC 497
>gi|143770880 laminin, beta 4 [Homo sapiens]
Length = 1761
Score = 270 bits (691), Expect = 1e-71
Identities = 175/571 (30%), Positives = 269/571 (47%), Gaps = 93/571 (16%)
Query: 48 HPTYFNL--AEAARIWATATCGERGPGEGRPQPELYCKLVGGPTAPGSGHTIQG-QFCDY 104
HPT +L ++ A++TCG + + YC L ++G Q C
Sbjct: 29 HPTTGDLLVGRNTQLMASSTCG-------LSRAQKYCIL----------SYLEGEQKCFI 71
Query: 105 CNSE------DPRKAHPVTNAI-----DGSERWWQSPPLSSGTQYNRVNLTLDLGQLFHV 153
C+S D +H + N I D ++WWQS + V++ LDL LF
Sbjct: 72 CDSRFPYDPYDQPNSHTIENVIVSFEPDREKKWWQSE-----NGLDHVSIRLDLEALFRF 126
Query: 154 AYILIKFANSPRPDLWVLERSVDFGSTYSPWQYFAHSKVDCLKEFGREANMAVTRDDDVL 213
+++++ F RP ++ERS D+G + ++YFA DC F + D++
Sbjct: 127 SHLILTFKTF-RPAAMLVERSTDYGHNWKVFKYFAK---DCATSFPNITSGQAQGVGDIV 182
Query: 214 CVTEYSRIVPLENGEVVVSLINGRPGAKNFTFSHTLREFTKATNIRLRFLRTNTLLGHLI 273
C ++YS I P GEVV+ +++ +N +S +++ TN+R+ F + +TL L+
Sbjct: 183 CDSKYSDIEPSTGGEVVLKVLDPSFEIEN-PYSPYIQDLVTLTNLRINFTKLHTLGDALL 241
Query: 274 SKAQRDPTVTRRYYYSIKDISIGGQCVCNGHAEVC--------NINNPEKLF--RCECQH 323
+ Q D +YYY++ ++ + G C CNGHA C ++ +P + +C CQH
Sbjct: 242 GRRQNDSL--DKYYYALYEMIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQH 299
Query: 324 HTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGI 383
+T G C+RC + WRPAA Q + C +C+C+ H+S C++D L+
Sbjct: 300 NTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLS---- 355
Query: 384 YAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPE----------HA 433
GGVC +CQHNT G +C++C +YR + P CIPC CDP+ H+
Sbjct: 356 ---GGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHS 412
Query: 434 D-GCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCD 492
D +G+C CK N G C++C +Y S+ DP+ + CD
Sbjct: 413 DPALGSVAGQCLCKENVEGAKCDQCKPNHYGL--------------SATDPLG--CQPCD 456
Query: 493 CNLEGVLPEI-CDAH-GRCLCRPGVEGPRCDTCRSGFYSFPI----CQACWCSALGSYQM 546
CN G LP + CD G+CLC V G C+ C G++ C C C G+Y
Sbjct: 457 CNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSN 516
Query: 547 PCSSVTGQCECRPGVTGQRCDRCLSGAYDFP 577
CS GQCECRP VTG+ C G + P
Sbjct: 517 VCSPKNGQCECRPHVTGRSCSEPAPGYFFAP 547
Score = 170 bits (430), Expect = 2e-41
Identities = 132/446 (29%), Positives = 170/446 (38%), Gaps = 81/446 (18%)
Query: 318 RCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQAS 377
+C C G CDRC GY C C C+ A C DP+
Sbjct: 835 QCPCHGEVSGRRCDRCLAGYFG----------FPSCHPCPCNRFAELC--DPET------ 876
Query: 378 LNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSC--DPEH--- 432
G C NC T G NCE+C GYY G P + C PC C DP
Sbjct: 877 ----------GSCFNCGGFTTGRNCERCIDGYY---GNP-SSGQPCRPCLCPDDPSSNQY 922
Query: 433 -ADGCEQGSGR----CHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGD 487
A C Q C+C + G C +C+ G+Y P P P +
Sbjct: 923 FAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCA----------- 971
Query: 488 IKGCDCNLEGVLPEICD-AHGRCL-CRPGVEGPRCDTCRSGFYSFPI---CQACWCSALG 542
C+ N++ PE C G CL C +G C C+ G Y + C+ C C A G
Sbjct: 972 ---CNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASG 1028
Query: 543 SYQMPC---------SSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSA-CDPAGTI 592
M C VTG C C P VTG CDRC G ++ +G S CDP +
Sbjct: 1029 VSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQ 1088
Query: 593 NSNL----GYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQG 648
+S+ G C CKL G CS C+ Y+ + P C C C++AGT C
Sbjct: 1089 SSHCDQLTGQCPCKLGYGGKRCSECQENYYG---DPPGRCIPCDCNRAGTQKPI--CDPD 1143
Query: 649 DGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREH 708
G C C+ V G CD C G+ + E C C +SS+ G+ + +
Sbjct: 1144 TGMCRCREGVSGQRCDRCARGH-SQEFPTCLQCHLCFDQWDHTISSLSKAVQGLMRLAAN 1202
Query: 709 VVGKVCQRPENNYYFPDLHHMKYEIE 734
+ K P F DL EIE
Sbjct: 1203 MEDKRETLPVCEADFKDLRGNVSEIE 1228
Score = 166 bits (421), Expect = 3e-40
Identities = 126/423 (29%), Positives = 165/423 (39%), Gaps = 73/423 (17%)
Query: 318 RCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHE-CEACNCHGHASNCYYDPDVERQQA 376
+C+C+ G CDRC TG +++ H C C+CH S D Q
Sbjct: 787 QCQCKPLVVGRCCDRCSTG---------SYDLGHHGCHPCHCHPQGSK-----DTVCDQV 832
Query: 377 SLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADGC 436
+ G C C +G C++C GY+ G P C PC C+ A+ C
Sbjct: 833 T----------GQC-PCHGEVSGRRCDRCLAGYF---GFP-----SCHPCPCN-RFAELC 872
Query: 437 EQGSGRC-HCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNL 495
+ +G C +C G NCE+C GYY P + P P P +DP + C
Sbjct: 873 DPETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQ-PCRPCLCP--DDPSSNQYFAHSC-- 927
Query: 496 EGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPI-----CQACWCSALGSYQMP--C 548
+ + C C G G +C C +GFY P CQ C C+ P C
Sbjct: 928 ---YQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESC 984
Query: 549 SSVTGQC-ECRPGVTGQRCDRCLSGAYDFP----------HCQG-SSSACDPAG---TIN 593
S VTG+C C G C C G Y H G S C P G +
Sbjct: 985 SRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCD 1044
Query: 594 SNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCH 653
G C C +V G C RC YWNL GC C C S + C Q G C
Sbjct: 1045 PVTGACPCLPNVTGLACDRCADGYWNLVPGR--GCQSCDCDPR--TSQSSHCDQLTGQCP 1100
Query: 654 CKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKV 713
CK GG C C++ Y+ C C C+ G +C +G+C+CRE V G+
Sbjct: 1101 CKLGYGGKRCSECQENYYGDPPGR---CIPCDCNRAGTQKPICDPDTGMCRCREGVSGQR 1157
Query: 714 CQR 716
C R
Sbjct: 1158 CDR 1160
Score = 163 bits (413), Expect = 2e-39
Identities = 92/279 (32%), Positives = 129/279 (46%), Gaps = 50/279 (17%)
Query: 506 HGRCLCRPGVEGPRCDTCRSGFYSFP----------ICQACWCSALGS--------YQMP 547
HG+C+C+ +GP C+ C+ F P C++C C++ S Y
Sbjct: 292 HGQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLAS 351
Query: 548 CSSVTGQCE-CRPGVTGQRCDRC-----------LSGAYDFPHCQGSSSACDPAGTINSN 595
G CE C+ GQ CDRC +S Y C+ CDP GTI+
Sbjct: 352 GGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCE-----CDPDGTISGG 406
Query: 596 L-------------GYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGT 642
+ G C CK +VEG C +CK ++ L +P GC C C+ G++
Sbjct: 407 ICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFL 466
Query: 643 GECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGV 702
C G C C S+V G C+ C GY+ L ++ GC C CDIGGA S++CS +G
Sbjct: 467 -TCDVDTGQCLCLSYVTGAHCEECTVGYWGLG-NHLHGCSPCDCDIGGAYSNVCSPKNGQ 524
Query: 703 CQCREHVVGKVCQRPENNYYFPDLHHMKYEIEDGSTPNG 741
C+CR HV G+ C P Y+F L+ YE E+ +T G
Sbjct: 525 CECRPHVTGRSCSEPAPGYFFAPLNFYLYEAEEATTLQG 563
Score = 148 bits (374), Expect = 8e-35
Identities = 110/373 (29%), Positives = 144/373 (38%), Gaps = 76/373 (20%)
Query: 387 GGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADG--CEQGSGRCH 444
GG C C+ G C++C+ G Y GC PC C P+ + C+Q +G+C
Sbjct: 785 GGQC-QCKPLVVGRCCDRCSTGSYDL------GHHGCHPCHCHPQGSKDTVCDQVTGQCP 837
Query: 445 CKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICD 504
C G C++C GY+ FP C C CN E+CD
Sbjct: 838 CHGEVSGRRCDRCLAGYFGFPSC---------------------HPCPCNR---FAELCD 873
Query: 505 AH-GRCL-CRPGVEGPRCDTCRSGFYSFPI----CQACWCS---------ALGSYQMPCS 549
G C C G C+ C G+Y P C+ C C A YQ S
Sbjct: 874 PETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWS 933
Query: 550 SVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNL------------G 597
S C C G TG +C C +G Y P G+ C P N+N+ G
Sbjct: 934 SDV-ICNCLQGYTGTQCGECSTGFYGNPRISGAP--CQPCAC-NNNIDVTDPESCSRVTG 989
Query: 598 YC-QCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTV-------SGTGECRQGD 649
C +C + +G C CK ++ C C CH +G G C
Sbjct: 990 ECLRCLHNTQGANCQLCKPGHYGSALNQT--CRRCSCHASGVSPMECPPGGGACLCDPVT 1047
Query: 650 GDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHV 709
G C C +V G +CD C DGY+ L GCQ C CD + SS C +G C C+
Sbjct: 1048 GACPCLPNVTGLACDRCADGYWNLVPGR--GCQSCDCDPRTSQSSHCDQLTGQCPCKLGY 1105
Query: 710 VGKVCQRPENNYY 722
GK C + NYY
Sbjct: 1106 GGKRCSECQENYY 1118
Score = 147 bits (372), Expect = 1e-34
Identities = 123/428 (28%), Positives = 177/428 (41%), Gaps = 61/428 (14%)
Query: 1070 LAHETPPTALILDVLSGRPFPHLPQQ-SSPS-VDVLPGVTLKAPQNQVTLRGRVPHLGRY 1127
L ET + + V+ G P P P + P VLPG L+ N + P +
Sbjct: 567 LGSETFGQSPAVHVVLGEPVPGNPVTWTGPGFARVLPGAGLRFAVNNI------PFPVDF 620
Query: 1128 VFVIHFYQAAHPTFPAQVSVDGGWPRAGSFHASFCPHVLGCRDQVIAEGQIEFDIS---- 1183
IH+ + + Q+ V+ P GS H P L + Q A +
Sbjct: 621 TIAIHYETQSAADWTVQIVVN---PPGGSEHC--IPKTLQSKPQSFALPAATRIMLLPTP 675
Query: 1184 ---EPEVAATVKVP-----EGKSLVLVRVLV-----VPAENYDYQILHKKSMDKSLEFIT 1230
EP+V ++ V +G+S VLV +P N K+ +D+ +
Sbjct: 676 ICLEPDVQYSIDVYFSQPLQGESHAHSHVLVDSLGLIPQINSLENFCSKQDLDEYQ--LH 733
Query: 1231 NCGKNSFYLDPQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPN 1290
NC + + + PQ C+ S+ A H GA+ C+CHP G+ G CS GGQC C+P
Sbjct: 734 NCVEIASAMGPQVLPGACERLIISMSAKLHDGAVACKCHPQGSVGSSCSRLGGQCQCKPL 793
Query: 1291 VIGRQCTRCATGHY--GFPRCKPCSCGRR-----LCEEMTGQCRCPPRTVRPQCEVCETH 1343
V+GR C RC+TG Y G C PC C + +C+++TGQC C +C+ C
Sbjct: 794 VVGRCCDRCSTGSYDLGHHGCHPCHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAG 853
Query: 1344 SFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQC-RCKPRITGRQCDRCASGFYRFPE- 1401
F F C C C+R + CD ++G C C TGR C+RC G+Y P
Sbjct: 854 YFGF---PSCHPCPCNRFAEL------CDPETGSCFNCGGFTTGRNCERCIDGYYGNPSS 904
Query: 1402 ---CVPCNCNRDGTE----PGVCDPGTGA----CLCKENVEGTECNVCREGSFHLDPANL 1450
C PC C D + C + C C + GT+C C G + +
Sbjct: 905 GQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISG 964
Query: 1451 KGCTSCFC 1458
C C C
Sbjct: 965 APCQPCAC 972
Score = 141 bits (356), Expect = 9e-33
Identities = 84/252 (33%), Positives = 113/252 (44%), Gaps = 43/252 (17%)
Query: 1230 TNCGKNS--FYLDPQTASRFCKNSARSLVAFYHKGALPCECHPT-GATGPH-CSPEGGQC 1285
T CG+ S FY +P+ + C+ PC C+ T P CS G+C
Sbjct: 947 TQCGECSTGFYGNPRISGAPCQ---------------PCACNNNIDVTDPESCSRVTGEC 991
Query: 1286 -PCQPNVIGRQCTRCATGHYGFP---RCKPCSC--------------GRRLCEEMTGQCR 1327
C N G C C GHYG C+ CSC G LC+ +TG C
Sbjct: 992 LRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACP 1051
Query: 1328 CPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGR 1387
C P C+ C ++ P GC+ C+C R + + CD+ +GQC CK G+
Sbjct: 1052 CLPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQSS---HCDQLTGQCPCKLGYGGK 1108
Query: 1388 QCDRCASGFYRFP--ECVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCREGSFHL 1445
+C C +Y P C+PC+CNR GT+ +CDP TG C C+E V G C+ C G
Sbjct: 1109 RCSECQENYYGDPPGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCARGHSQE 1168
Query: 1446 DPANLKGCTSCF 1457
P L+ C CF
Sbjct: 1169 FPTCLQ-CHLCF 1179
Score = 140 bits (354), Expect = 2e-32
Identities = 98/332 (29%), Positives = 130/332 (39%), Gaps = 50/332 (15%)
Query: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGY--NQRRWRPAAWEQSHECEAC 356
C CN AE+C+ PE C T G C+RC GY N +P C C
Sbjct: 863 CPCNRFAELCD---PETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQP--------CRPC 911
Query: 357 NCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVP 416
C DP + A Q +++ +C NC G C +C+ G+Y G P
Sbjct: 912 LCPD-------DPSSNQYFAHSCYQNLWSSDVIC-NCLQGYTGTQCGECSTGFY---GNP 960
Query: 417 VDAPDGCIPCSC----DPEHADGCEQGSGRC-HCKPNFHGDNCEKCAIGYYNFPF---CL 468
+ C PC+C D + C + +G C C N G NC+ C G+Y C
Sbjct: 961 RISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCR 1020
Query: 469 RIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFY 528
R E P G CD G C C P V G CD C G++
Sbjct: 1021 RCSCHASGVSPMECPPGGGACLCD-----------PVTGACPCLPNVTGLACDRCADGYW 1069
Query: 529 SFPI---CQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSA 585
+ CQ+C C S C +TGQC C+ G G+RC C Y P +
Sbjct: 1070 NLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYGDPPGRCIPCD 1129
Query: 586 CDPAGT----INSNLGYCQCKLHVEGPTCSRC 613
C+ AGT + + G C+C+ V G C RC
Sbjct: 1130 CNRAGTQKPICDPDTGMCRCREGVSGQRCDRC 1161
Score = 135 bits (340), Expect = 7e-31
Identities = 68/163 (41%), Positives = 85/163 (52%), Gaps = 16/163 (9%)
Query: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGE 1713
C C +G C C GY+ C PC CN + C +G C NC T G
Sbjct: 836 CPCHGEVSGRRCDRCLAGYFGFPS------CHPCPCNRFAELCDPETGSCFNCGGFTTGR 889
Query: 1714 HCERCQEGYYGNAVHGS-CRACPCPHTNS----FATGCVVN--GGDVRCSCKAGYTGTQC 1766
+CERC +GYYGN G CR C CP S FA C N DV C+C GYTGTQC
Sbjct: 890 NCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQC 949
Query: 1767 ERCAPGYFGNPQKFGGSCQPCSCNSNGQL---GSCHPLTGDCI 1806
C+ G++GNP+ G CQPC+CN+N + SC +TG+C+
Sbjct: 950 GECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECL 992
Score = 113 bits (283), Expect = 3e-24
Identities = 79/253 (31%), Positives = 103/253 (40%), Gaps = 31/253 (12%)
Query: 491 CDCNLEGVLPEICDA-HGRCLCRPGVEGPRCDTCRSGFYSFPI--CQACWCSALGSYQMP 547
C C+ +G + C G+C C+P V G CD C +G Y C C C GS
Sbjct: 769 CKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQGSKDTV 828
Query: 548 CSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGS-----SSACDPAGTINSNLGYC-QC 601
C VTGQC C V+G+RCDRCL+G + FP C + CDP G C C
Sbjct: 829 CDQVTGQCPCHGEVSGRRCDRCLAGYFGFPSCHPCPCNRFAELCDP------ETGSCFNC 882
Query: 602 KLHVEGPTCSRCKLLYWNLDKENPSG---CSECKC--HKAGTVSGTGECRQ----GDGDC 652
G C RC Y+ NPS C C C + C Q D C
Sbjct: 883 GGFTTGRNCERCIDGYYG----NPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVIC 938
Query: 653 HCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQC--DIGGALSSMCSGPSGVC-QCREHV 709
+C G C C G++ + + CQ C C +I CS +G C +C +
Sbjct: 939 NCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNT 998
Query: 710 VGKVCQRPENNYY 722
G CQ + +Y
Sbjct: 999 QGANCQLCKPGHY 1011
Score = 110 bits (274), Expect = 3e-23
Identities = 59/182 (32%), Positives = 81/182 (44%), Gaps = 16/182 (8%)
Query: 1653 ICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSN-----QCQDGSGICVNCQ 1707
IC C Y G C CS G+Y + + + C PC CN + + C +G C+ C
Sbjct: 937 ICNCLQGYTGTQCGECSTGFYGNPR-ISGAPCQPCACNNNIDVTDPESCSRVTGECLRCL 995
Query: 1708 HNTAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDV-------RCSCKAG 1760
HNT G +C+ C+ G+YG+A++ +CR C C + C GG C C
Sbjct: 996 HNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPN 1055
Query: 1761 YTGTQCERCAPGYFGNPQKFGGSCQPCSCN-SNGQLGSCHPLTGDCINQEPKDSSPAEEC 1819
TG C+RCA GY+ G CQ C C+ Q C LTG C + EC
Sbjct: 1056 VTGLACDRCADGYWNLVP--GRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSEC 1113
Query: 1820 DD 1821
+
Sbjct: 1114 QE 1115
Score = 102 bits (253), Expect = 8e-21
Identities = 56/195 (28%), Positives = 84/195 (43%), Gaps = 29/195 (14%)
Query: 1654 CACPPAYAGDSCQGCSPGY----YRDHKGLYTGRCVPCNCNGHSNQCQD----------- 1698
C C G +C+ C + +R L C C+CN HS++C
Sbjct: 295 CVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGL 354
Query: 1699 GSGICVNCQHNTAGEHCERCQEGYYGNAVHG-----SCRACPCPHTNSFATGCVVNGGDV 1753
G+C +CQHNT G+HC+RC+ +Y + + +C C C + + G V+ D
Sbjct: 355 SGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDP 414
Query: 1754 -------RCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLG--SCHPLTGD 1804
+C CK G +C++C P ++G CQPC CN G L +C TG
Sbjct: 415 ALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQ 474
Query: 1805 CINQEPKDSSPAEEC 1819
C+ + EEC
Sbjct: 475 CLCLSYVTGAHCEEC 489
Score = 96.3 bits (238), Expect = 5e-19
Identities = 56/191 (29%), Positives = 79/191 (41%), Gaps = 31/191 (16%)
Query: 1282 GGQCP-CQPNVIGRQCTRCATGHYGFP--------RCKPCSC------GRRLCEE----- 1321
GG C CQ N G+ C RC Y P C PC C +C
Sbjct: 356 GGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDPA 415
Query: 1322 ---MTGQCRCPPRTVRPQCEVCETHSFSFHPM--AGCEGCNCSRRGTIEAAMPECDRDSG 1376
+ GQC C +C+ C+ + + GC+ C+C+ G++ CD D+G
Sbjct: 416 LGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLT--CDVDTG 473
Query: 1377 QCRCKPRITGRQCDRCASGFYRFPE----CVPCNCNRDGTEPGVCDPGTGACLCKENVEG 1432
QC C +TG C+ C G++ C PC+C+ G VC P G C C+ +V G
Sbjct: 474 QCLCLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTG 533
Query: 1433 TECNVCREGSF 1443
C+ G F
Sbjct: 534 RSCSEPAPGYF 544
Score = 93.6 bits (231), Expect = 3e-18
Identities = 51/158 (32%), Positives = 67/158 (42%), Gaps = 24/158 (15%)
Query: 1264 LPCECHPTGA---------TGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPR-----C 1309
+PCEC P G + P GQC C+ NV G +C +C HYG C
Sbjct: 393 IPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGC 452
Query: 1310 KPCSCGR------RLCEEMTGQCRCPPRTVRPQCEVCETHSFSF-HPMAGCEGCNCSRRG 1362
+PC C C+ TGQC C CE C + + + GC C+C G
Sbjct: 453 QPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGG 512
Query: 1363 TIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFP 1400
A C +GQC C+P +TGR C A G++ P
Sbjct: 513 ---AYSNVCSPKNGQCECRPHVTGRSCSEPAPGYFFAP 547
Score = 93.2 bits (230), Expect = 4e-18
Identities = 73/237 (30%), Positives = 89/237 (37%), Gaps = 46/237 (19%)
Query: 1267 ECHPTGAT-GPHCSPEG---GQCPCQPNVIGRQCTRCATGHYGFP----------RCKPC 1312
EC P G SP G GQC CQ N G C RC P C+ C
Sbjct: 273 ECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSC 332
Query: 1313 SCGR---RLCEEMT----------GQCR-CPPRTVRPQCEVCETHSF-----SFHPMAGC 1353
SC R +MT G C C T C+ C + + C
Sbjct: 333 SCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYAC 392
Query: 1354 EGCNCSRRGTIEAAM------PECDRDSGQCRCKPRITGRQCDRCASGFYRFPE-----C 1402
C C GTI + P +GQC CK + G +CD+C Y C
Sbjct: 393 IPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGC 452
Query: 1403 VPCNCNRDGTEPGV-CDPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFC 1458
PC+CN G+ P + CD TG CLC V G C C G + L +L GC+ C C
Sbjct: 453 QPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLG-NHLHGCSPCDC 508
Score = 91.3 bits (225), Expect = 1e-17
Identities = 58/201 (28%), Positives = 81/201 (40%), Gaps = 24/201 (11%)
Query: 535 ACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGT--- 591
AC C GS CS + GQC+C+P V G+ CDRC +G+YD H C P G+
Sbjct: 768 ACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQGSKDT 827
Query: 592 -INSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDG 650
+ G C C V G C RC Y+ PS C C C++ + C G
Sbjct: 828 VCDQVTGQCPCHGEVSGRRCDRCLAGYFGF----PS-CHPCPCNRFAEL-----CDPETG 877
Query: 651 DC-HCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCS--------GPSG 701
C +C G +C+ C DGY+ S C+ C C + + +
Sbjct: 878 SCFNCGGFTTGRNCERCIDGYYGNPSSGQ-PCRPCLCPDDPSSNQYFAHSCYQNLWSSDV 936
Query: 702 VCQCREHVVGKVCQRPENNYY 722
+C C + G C +Y
Sbjct: 937 ICNCLQGYTGTQCGECSTGFY 957
Score = 78.6 bits (192), Expect = 1e-13
Identities = 49/132 (37%), Positives = 57/132 (43%), Gaps = 13/132 (9%)
Query: 1676 HKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACP 1735
H G +C P G S C G C C+ G C+RC G Y HG C C
Sbjct: 763 HDGAVACKCHPQGSVGSS--CSRLGGQC-QCKPLVVGRCCDRCSTGSYDLGHHG-CHPCH 818
Query: 1736 CPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQL 1795
C S T C G +C C +G +C+RC GYFG P SC PC CN +L
Sbjct: 819 CHPQGSKDTVCDQVTG--QCPCHGEVSGRRCDRCLAGYFGFP-----SCHPCPCNRFAEL 871
Query: 1796 GSCHPLTGDCIN 1807
C P TG C N
Sbjct: 872 --CDPETGSCFN 881
Score = 77.0 bits (188), Expect = 3e-13
Identities = 45/133 (33%), Positives = 57/133 (42%), Gaps = 11/133 (8%)
Query: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSN----QCQDGSGICVNCQHN 1709
C C G C C P +Y G C PC+CN + C +G C+ C
Sbjct: 423 CLCKENVEGAKCDQCKPNHYGLSATDPLG-CQPCDCNPLGSLPFLTCDVDTGQCL-CLSY 480
Query: 1710 TAGEHCERCQEGYYG--NAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCE 1767
G HCE C GY+G N +HG C C C +++ C G +C C+ TG C
Sbjct: 481 VTGAHCEECTVGYWGLGNHLHG-CSPCDCDIGGAYSNVCSPKNG--QCECRPHVTGRSCS 537
Query: 1768 RCAPGYFGNPQKF 1780
APGYF P F
Sbjct: 538 EPAPGYFFAPLNF 550
Score = 72.4 bits (176), Expect = 7e-12
Identities = 38/116 (32%), Positives = 53/116 (45%), Gaps = 6/116 (5%)
Query: 613 CKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFA 672
C+ L ++ + G CKCH G+V + C + G C CK V G CD C G +
Sbjct: 751 CERLIISMSAKLHDGAVACKCHPQGSVGSS--CSRLGGQCQCKPLVVGRCCDRCSTGSYD 808
Query: 673 LEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENNYY-FPDLH 727
L + GC C C G+ ++C +G C C V G+ C R Y+ FP H
Sbjct: 809 L---GHHGCHPCHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFPSCH 861
Score = 69.7 bits (169), Expect = 5e-11
Identities = 50/192 (26%), Positives = 83/192 (43%), Gaps = 51/192 (26%)
Query: 1672 YYRDHKGLYTGRCVPCNCNGHSNQCQDGS--------------GICVNCQHNTAGEHCER 1717
YY ++ + G C CNGH+++C+ G CV CQHNT G +CER
Sbjct: 253 YYALYEMIVRGSCF---CNGHASECRPMQKMRGDVFSPPGMVHGQCV-CQHNTDGPNCER 308
Query: 1718 CQEGYY-------GNAVHGSCRACPCPHTNSFATGCVVN----------GGDVRCSCKAG 1760
C++ + + +CR+C C NS ++ C + G V C+
Sbjct: 309 CKDFFQDAPWRPAADLQDNACRSCSC---NSHSSRCHFDMTTYLASGGLSGGVCEDCQHN 365
Query: 1761 YTGTQCERCAPGYFGNPQKFGG---SCQPCSCNSNGQL--GSC--------HPLTGDCIN 1807
G C+RC P ++ +P K +C PC C+ +G + G C + G C+
Sbjct: 366 TEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLC 425
Query: 1808 QEPKDSSPAEEC 1819
+E + + ++C
Sbjct: 426 KENVEGAKCDQC 437
Score = 60.8 bits (146), Expect = 2e-08
Identities = 32/100 (32%), Positives = 40/100 (40%), Gaps = 10/100 (10%)
Query: 1248 CKNSARSLVAFYHKGALPCECHPTGATG-PHCSPEGGQCPCQPNVIGRQCTRCATGHYGF 1306
CK + L A G PC+C+P G+ C + GQC C V G C C G++G
Sbjct: 437 CKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGL 496
Query: 1307 PR----CKPCSCG-----RRLCEEMTGQCRCPPRTVRPQC 1337
C PC C +C GQC C P C
Sbjct: 497 GNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSC 536
Score = 52.0 bits (123), Expect = 1e-05
Identities = 21/46 (45%), Positives = 28/46 (60%)
Query: 1262 GALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFP 1307
G PC+C GA CSP+ GQC C+P+V GR C+ A G++ P
Sbjct: 502 GCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYFFAP 547
Score = 46.6 bits (109), Expect = 4e-04
Identities = 25/80 (31%), Positives = 34/80 (42%), Gaps = 6/80 (7%)
Query: 1727 VHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQP 1786
+H AC C S + C GG +C CK G C+RC+ G + C P
Sbjct: 762 LHDGAVACKCHPQGSVGSSCSRLGG--QCQCKPLVVGRCCDRCSTGSYDLGHH---GCHP 816
Query: 1787 CSCNSNGQLGS-CHPLTGDC 1805
C C+ G + C +TG C
Sbjct: 817 CHCHPQGSKDTVCDQVTGQC 836
Score = 43.1 bits (100), Expect = 0.005
Identities = 22/63 (34%), Positives = 30/63 (47%), Gaps = 2/63 (3%)
Query: 666 CEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENNYYFPD 725
CE ++ + G C+C G++ S CS G CQC+ VVG+ C R Y D
Sbjct: 751 CERLIISMSAKLHDGAVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSY--D 808
Query: 726 LHH 728
L H
Sbjct: 809 LGH 811
Score = 35.4 bits (80), Expect = 0.95
Identities = 25/113 (22%), Positives = 55/113 (48%), Gaps = 1/113 (0%)
Query: 1839 QLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDL 1898
Q R +KS+L+ +GL + + ++T+ + ++ +N + + + LE+E +L
Sbjct: 1610 QTREMKSELELAKQRSGLEDGLSLLQTKLQRHQDHAVNAKVQAESAQHQAGSLEKEFVEL 1669
Query: 1899 NQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHILLKQI 1951
+++ LQ K +TL V + +A++L + IR + L ++I
Sbjct: 1670 KKQYAILQRKTSTTGLTKETL-GKVKQLKDAAEKLAGDTEAKIRRITDLERKI 1721
Score = 33.9 bits (76), Expect = 2.8
Identities = 28/104 (26%), Positives = 42/104 (40%), Gaps = 29/104 (27%)
Query: 1387 RQCDRCASGFYRFPECV---PCNCNRDGTE--------------PGVCDPGTGACLCKEN 1429
RQ D +Y E + C CN +E PG+ G C+C+ N
Sbjct: 244 RQNDSLDKYYYALYEMIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVH---GQCVCQHN 300
Query: 1430 VEGTECNVCREGSFHLDP-----ANLK--GCTSCFCFGVNNQCH 1466
+G C C++ F D A+L+ C SC C +++CH
Sbjct: 301 TDGPNCERCKD--FFQDAPWRPAADLQDNACRSCSCNSHSSRCH 342
Score = 33.5 bits (75), Expect = 3.6
Identities = 27/113 (23%), Positives = 46/113 (40%), Gaps = 21/113 (18%)
Query: 1725 NAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQK----- 1779
N CR + F+ +V+G +C C+ G CERC + P +
Sbjct: 268 NGHASECRPMQKMRGDVFSPPGMVHG---QCVCQHNTDGPNCERCKDFFQDAPWRPAADL 324
Query: 1780 FGGSCQPCSCNSNGQLGSCH----------PLTGDCINQEPKDSSPAEECDDC 1822
+C+ CSCNS+ CH L+G + ++ + ++ + CD C
Sbjct: 325 QDNACRSCSCNSHS--SRCHFDMTTYLASGGLSGG-VCEDCQHNTEGQHCDRC 374
>gi|62868217 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 269 bits (688), Expect = 3e-71
Identities = 186/593 (31%), Positives = 262/593 (44%), Gaps = 97/593 (16%)
Query: 62 ATATCGERGPGEGRPQPELYCKLVGGPTAPGSGHTIQGQF-CDYCNSEDPRK--AHPVTN 118
A++TCG +PE YC G + Q C C+S P +H V N
Sbjct: 43 ASSTCG-------LTKPETYCTQYG-----------EWQMKCCKCDSRQPHNYYSHRVEN 84
Query: 119 AID--GSERWWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVD 176
G RWWQS N V+L LDL + F + ++++F P P ++ERS D
Sbjct: 85 VASSSGPMRWWQSQ-----NDVNPVSLQLDLDRRFQLQEVMMEF-QGPMPAGMLIERSSD 138
Query: 177 FGSTYSPWQYFAHSKVDCLKEFGREANMAVTRDDDVLCVTEYSRIVPLENGEVV----VS 232
FG T+ +QY A DC F R DV C + R NG V +
Sbjct: 139 FGKTWRVYQYLA---ADCTSTFPRVRQGRPQSWQDVRCQSLPQRPNARLNGGKVQLNLMD 195
Query: 233 LINGRPGAKNFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDPTVTRRYYYSIKD 292
L++G P T S ++E + TN+R+ F R L + + P+ YY++
Sbjct: 196 LVSGIPA----TQSQKIQEVGEITNLRVNFTR----LAPVPQRGYHPPSA----YYAVSQ 243
Query: 293 ISIGGQCVCNGHAEVCNIN-----NPEKLFR----CECQHHTCGETCDRCCTGYNQRRWR 343
+ + G C C+GHA+ C P + C CQH+T G C+RC YN R WR
Sbjct: 244 LRLQGSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWR 303
Query: 344 PAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCE 403
PA + +HEC+ C+C+GH+ C++DP V +QG Y GGVC NC+ +T G NCE
Sbjct: 304 PAEGQDAHECQRCDCNGHSETCHFDPAV-----FAASQGAY--GGVCDNCRDHTEGKNCE 356
Query: 404 QCAKGYYRPYGVPVDAPDGCIPCSCDPEHA---DGCEQGSGRCHCKPNFHGDNCEKCAIG 460
+C Y+R + CI C CDP+ A C+ +G+C CK + G+ C+ C G
Sbjct: 357 RCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPG 416
Query: 461 YYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEI-CDAH-GRCLCRPGVEGP 518
+ + + P CDCN+ G ++ CD GRCLC P V GP
Sbjct: 417 FTGLTY---------ANPQG-------CHRCDCNILGSRRDMPCDEESGRCLCLPNVVGP 460
Query: 519 RCDTCRSGFYSFPI---CQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCD-----RCL 570
+CD C + C+ C C S C+ TGQC CR G G C +C
Sbjct: 461 KCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCP 520
Query: 571 SGAYDFPHCQGSSSACDPAGT----INSNLGYCQCKLHVEGPTCSRCKLLYWN 619
Y + CD GT + G C C+ + GP C +C+ Y N
Sbjct: 521 DRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCN 573
Score = 129 bits (324), Expect = 5e-29
Identities = 99/346 (28%), Positives = 131/346 (37%), Gaps = 74/346 (21%)
Query: 426 CSCDPEHADGCEQGSGR-------------CHCKPNFHGDNCEKCAIGYYNFPFCLRIPI 472
C C HAD C G C C+ N G NCE+CA Y N P+
Sbjct: 250 CFCHG-HADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPW------ 302
Query: 473 FPVSTPSSEDPVAGDIKGCDCN---------------LEGVLPEICDAHGRCLCRPGVEG 517
+E A + + CDCN +G +CD CR EG
Sbjct: 303 -----RPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDN-----CRDHTEG 352
Query: 518 PRCDTC--------RSGFYSFPICQACWCSALGSYQ-MPCSSVTGQCECRPGVTGQRCDR 568
C+ C R G C +C C G+ PC VTGQC C+ V G+RCD
Sbjct: 353 KNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDL 412
Query: 569 CLSG--AYDFPHCQGSSSA-CDPAGT-----INSNLGYCQCKLHVEGPTCSRCKLLYWNL 620
C G + + QG C+ G+ + G C C +V GP C +C +W L
Sbjct: 413 CKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKL 472
Query: 621 DKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDT-----CEDGYFALEK 675
+ GC C C ++S +C Q G C C+ GG C C D +
Sbjct: 473 --ASGQGCEPCACDPHNSLSP--QCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVA 528
Query: 676 SNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENNY 721
+ GC+ C CD G C SG C CR + G C + + Y
Sbjct: 529 T---GCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGY 571
Score = 124 bits (311), Expect = 2e-27
Identities = 67/215 (31%), Positives = 97/215 (45%), Gaps = 27/215 (12%)
Query: 1264 LPCECHPTGAT-GPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCGR------ 1316
+ CEC P GA G C P GQC C+ +V G +C C G G P C R
Sbjct: 377 ISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNIL 436
Query: 1317 -----RLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPEC 1371
C+E +G+C C P V P+C+ C + + GCE C C ++ P+C
Sbjct: 437 GSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLS---PQC 493
Query: 1372 DRDSGQCRCKPRITGRQCDRCASGFYRFPE---------CVPCNCNRDGTEPGVCDPGTG 1422
++ +GQC C+ G C A+ + P+ C C+C+ GTE CD +G
Sbjct: 494 NQFTGQCPCREGFGGLMCS--AAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASG 551
Query: 1423 ACLCKENVEGTECNVCREGSFHLDPANLKGCTSCF 1457
CLC+ + G C+ C+ G + P + C CF
Sbjct: 552 RCLCRPGLTGPRCDQCQRGYCNRYPVCV-ACHPCF 585
Score = 99.8 bits (247), Expect = 4e-20
Identities = 74/237 (31%), Positives = 95/237 (40%), Gaps = 40/237 (16%)
Query: 1258 FYHKGALPCECHPTGATGPHCSPEGGQ-CPCQPNVIGRQCTRCATGHYGFP--------- 1307
F H A C P + GP + + C CQ N G C RCA + P
Sbjct: 251 FCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDA 310
Query: 1308 -RCKPCSCG--RRLCE-----------EMTGQC-RCPPRTVRPQCEVCETHSF-SFHPMA 1351
C+ C C C G C C T CE C+ H F + P A
Sbjct: 311 HECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGA 370
Query: 1352 G----CEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGF----YRFPE-C 1402
C C C G + A CD +GQC CK + G +CD C GF Y P+ C
Sbjct: 371 SIQETCISCECDPDGAVPGA--PCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGC 428
Query: 1403 VPCNCNRDGTEPGV-CDPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFC 1458
C+CN G+ + CD +G CLC NV G +C+ C +H A+ +GC C C
Sbjct: 429 HRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQC--APYHWKLASGQGCEPCAC 483
Score = 95.9 bits (237), Expect = 6e-19
Identities = 60/197 (30%), Positives = 87/197 (44%), Gaps = 34/197 (17%)
Query: 1652 EICACPPAYAGDSCQGCSPGY----YRDHKGLYTGRCVPCNCNGHSNQCQDG-------- 1699
++C C AG +C+ C+P Y +R +G C C+CNGHS C
Sbjct: 277 DVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQ 336
Query: 1700 ---SGICVNCQHNTAGEHCERCQEGYY-----GNAVHGSCRACPCPHTNSFATGCVVNGG 1751
G+C NC+ +T G++CERCQ Y+ G ++ +C +C C + G +
Sbjct: 337 GAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCEC-DPDGAVPGAPCDPV 395
Query: 1752 DVRCSCKAGYTGTQCERCAPGYFG----NPQKFGGSCQPCSCNSNGQLGS--CHPLTGDC 1805
+C CK G +C+ C PG+ G NPQ C C CN G C +G C
Sbjct: 396 TGQCVCKEHVQGERCDLCKPGFTGLTYANPQ----GCHRCDCNILGSRRDMPCDEESGRC 451
Query: 1806 INQEPKDSSPAEECDDC 1822
+ P P +CD C
Sbjct: 452 LCL-PNVVGP--KCDQC 465
Score = 84.3 bits (207), Expect = 2e-15
Identities = 150/716 (20%), Positives = 272/716 (37%), Gaps = 85/716 (11%)
Query: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGR-CVPCNCNGHSN---QCQDGSGICVNCQHN 1709
C C P G C C+P +++ L +G+ C PC C+ H++ QC +G C C+
Sbjct: 451 CLCLPNVVGPKCDQCAPYHWK----LASGQGCEPCACDPHNSLSPQCNQFTGQCP-CREG 505
Query: 1710 TAGEHCE-----RCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGT 1764
G C +C + YG+ G CRAC C + GC G RC C+ G TG
Sbjct: 506 FGGLMCSAAAIRQCPDRTYGDVATG-CRACDCDFRGTEGPGCDKASG--RCLCRPGLTGP 562
Query: 1765 QCERCAPGYFGNPQKFGGSCQPC-----------------SCNSNGQLGSCHPLTGDCIN 1807
+C++C GY N +C PC N+ L S L +
Sbjct: 563 RCDQCQRGYC-NRYPVCVACHPCFQTYDADLREQALRFGRLRNATASLWSGPGLEDRGLA 621
Query: 1808 QEPKDS-SPAEECDDCDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQ 1866
D+ S E+ S ++A + + ++ LQGL L E+ +
Sbjct: 622 SRILDAKSKIEQIRAVLSSPAVTEQEVAQVASAILSLRRTLQGLQLDLPLEEETLSL--- 678
Query: 1867 AKDLRNQLLNYRSAISNHGSKIEGLER-ELTDLNQEFETLQEKAQVNSRKAQTLNNNVNR 1925
+DL + ++ ++ + K E E+ D + F L + +++ AQ +
Sbjct: 679 PRDLESLDRSFNGLLTMYQRKREQFEKISSADPSGAFRMLSTAYEQSAQAAQ-------Q 731
Query: 1926 ATQSAKELDVKIKNVIRNVHILLKQISGTDGEGNNVPSGDFSREWAEAQRMMRELRNRNF 1985
+ S++ LD ++++ R L++Q G G G+ P R + + N+
Sbjct: 732 VSDSSRLLD-QLRDSRREAERLVRQAGGGGGTGS--PKLVALRLEMSSLPDLTPTFNKLC 788
Query: 1986 GKHLREA--------EADKRESQLLLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSD 2037
G + A E +++ G +A + + L + A+L
Sbjct: 789 GNSRQMACTPISCPGELCPQDNGTACGSRCRGVLPRAGGAFLMAGQVAEQLRGFNAQLQR 848
Query: 2038 LRARLQEAAAQAKQANGLNQENERALGAIQRQVKE----INSLQSDFTKYLTTADS---- 2089
R ++ A A Q Q E + A + Q++E L +LT D+
Sbjct: 849 TRQMIRAAEESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAAT 908
Query: 2090 --SLLQTNIALQLMEKS------QKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEE 2141
+ + +AL L S E + +AA L LS ++++R+ + EE
Sbjct: 909 IQEVSEAVLALWLPTDSATVLQKMNEIQAIAARLPNVDLVLSQTKQDIARARRLQAEAEE 968
Query: 2142 AEKHARSLQELAKQLEEIKRN-ASGDELVRCAVDAATAYENILNAIKAAEDAANRAASAS 2200
A A +++ Q+E++ N G ++ A D L I+ + +
Sbjct: 969 ARSRAHAVE---GQVEDVVGNLRQGTVALQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPA 1025
Query: 2201 ESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKE 2260
E + ++ K+ + ++L ++A+ + Q A +Q L+ E
Sbjct: 1026 EKLVTSMTKQ-----LGDFWTRMEELRHQARQQGAEAVQAQQLAEGASEQALS-AQEGFE 1079
Query: 2261 VIDTNLTTLRDGL-HGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVER 2315
I L+D L G+ A I S K+ + T E++D + ++ ++ R
Sbjct: 1080 RIKQKYAELKDRLGQSSMLGEQGARIQSVKTEAEELFGETMEMMDRMKDMELELLR 1135
Score = 72.4 bits (176), Expect = 7e-12
Identities = 54/170 (31%), Positives = 73/170 (42%), Gaps = 40/170 (23%)
Query: 1687 CNCNGHSNQCQDGSG-------------ICVNCQHNTAGEHCERCQEGY--------YGN 1725
C C+GH+++C G +CV CQHNTAG +CERC Y G
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERCAPFYNNRPWRPAEGQ 308
Query: 1726 AVHGSCRACPC-PHTNS-------FATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNP 1777
H C+ C C H+ + FA GG V +C+ G CERC YF N
Sbjct: 309 DAH-ECQRCDCNGHSETCHFDPAVFAASQGAYGG-VCDNCRDHTEGKNCERCQLHYFRNR 366
Query: 1778 Q---KFGGSCQPCSCNSNGQL--GSCHPLTGDCINQEPKDSSPAEECDDC 1822
+ +C C C+ +G + C P+TG C+ K+ E CD C
Sbjct: 367 RPGASIQETCISCECDPDGAVPGAPCDPVTGQCV---CKEHVQGERCDLC 413
Score = 61.6 bits (148), Expect = 1e-08
Identities = 32/109 (29%), Positives = 49/109 (44%), Gaps = 13/109 (11%)
Query: 1261 KGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCT-----RCATGHYG--FPRCKPCS 1313
+G PC C P + P C+ GQCPC+ G C+ +C YG C+ C
Sbjct: 476 QGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACD 535
Query: 1314 CGRR-----LCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPM-AGCEGC 1356
C R C++ +G+C C P P+C+ C+ + +P+ C C
Sbjct: 536 CDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPC 584
Score = 42.0 bits (97), Expect = 0.010
Identities = 31/114 (27%), Positives = 45/114 (39%), Gaps = 22/114 (19%)
Query: 631 CKCH--------KAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYF-----ALEKSN 677
C CH K G +G Q C C+ + G +C+ C Y E +
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQD 309
Query: 678 YFGCQGCQCD-------IGGALSSMCSGP-SGVCQ-CREHVVGKVCQRPENNYY 722
CQ C C+ A+ + G GVC CR+H GK C+R + +Y+
Sbjct: 310 AHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYF 363
>gi|62868215 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 269 bits (688), Expect = 3e-71
Identities = 186/593 (31%), Positives = 262/593 (44%), Gaps = 97/593 (16%)
Query: 62 ATATCGERGPGEGRPQPELYCKLVGGPTAPGSGHTIQGQF-CDYCNSEDPRK--AHPVTN 118
A++TCG +PE YC G + Q C C+S P +H V N
Sbjct: 43 ASSTCG-------LTKPETYCTQYG-----------EWQMKCCKCDSRQPHNYYSHRVEN 84
Query: 119 AID--GSERWWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVD 176
G RWWQS N V+L LDL + F + ++++F P P ++ERS D
Sbjct: 85 VASSSGPMRWWQSQ-----NDVNPVSLQLDLDRRFQLQEVMMEF-QGPMPAGMLIERSSD 138
Query: 177 FGSTYSPWQYFAHSKVDCLKEFGREANMAVTRDDDVLCVTEYSRIVPLENGEVV----VS 232
FG T+ +QY A DC F R DV C + R NG V +
Sbjct: 139 FGKTWRVYQYLA---ADCTSTFPRVRQGRPQSWQDVRCQSLPQRPNARLNGGKVQLNLMD 195
Query: 233 LINGRPGAKNFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDPTVTRRYYYSIKD 292
L++G P T S ++E + TN+R+ F R L + + P+ YY++
Sbjct: 196 LVSGIPA----TQSQKIQEVGEITNLRVNFTR----LAPVPQRGYHPPSA----YYAVSQ 243
Query: 293 ISIGGQCVCNGHAEVCNIN-----NPEKLFR----CECQHHTCGETCDRCCTGYNQRRWR 343
+ + G C C+GHA+ C P + C CQH+T G C+RC YN R WR
Sbjct: 244 LRLQGSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWR 303
Query: 344 PAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCE 403
PA + +HEC+ C+C+GH+ C++DP V +QG Y GGVC NC+ +T G NCE
Sbjct: 304 PAEGQDAHECQRCDCNGHSETCHFDPAV-----FAASQGAY--GGVCDNCRDHTEGKNCE 356
Query: 404 QCAKGYYRPYGVPVDAPDGCIPCSCDPEHA---DGCEQGSGRCHCKPNFHGDNCEKCAIG 460
+C Y+R + CI C CDP+ A C+ +G+C CK + G+ C+ C G
Sbjct: 357 RCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPG 416
Query: 461 YYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEI-CDAH-GRCLCRPGVEGP 518
+ + + P CDCN+ G ++ CD GRCLC P V GP
Sbjct: 417 FTGLTY---------ANPQG-------CHRCDCNILGSRRDMPCDEESGRCLCLPNVVGP 460
Query: 519 RCDTCRSGFYSFPI---CQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCD-----RCL 570
+CD C + C+ C C S C+ TGQC CR G G C +C
Sbjct: 461 KCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCP 520
Query: 571 SGAYDFPHCQGSSSACDPAGT----INSNLGYCQCKLHVEGPTCSRCKLLYWN 619
Y + CD GT + G C C+ + GP C +C+ Y N
Sbjct: 521 DRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCN 573
Score = 129 bits (324), Expect = 5e-29
Identities = 99/346 (28%), Positives = 131/346 (37%), Gaps = 74/346 (21%)
Query: 426 CSCDPEHADGCEQGSGR-------------CHCKPNFHGDNCEKCAIGYYNFPFCLRIPI 472
C C HAD C G C C+ N G NCE+CA Y N P+
Sbjct: 250 CFCHG-HADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPW------ 302
Query: 473 FPVSTPSSEDPVAGDIKGCDCN---------------LEGVLPEICDAHGRCLCRPGVEG 517
+E A + + CDCN +G +CD CR EG
Sbjct: 303 -----RPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDN-----CRDHTEG 352
Query: 518 PRCDTC--------RSGFYSFPICQACWCSALGSYQ-MPCSSVTGQCECRPGVTGQRCDR 568
C+ C R G C +C C G+ PC VTGQC C+ V G+RCD
Sbjct: 353 KNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDL 412
Query: 569 CLSG--AYDFPHCQGSSSA-CDPAGT-----INSNLGYCQCKLHVEGPTCSRCKLLYWNL 620
C G + + QG C+ G+ + G C C +V GP C +C +W L
Sbjct: 413 CKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKL 472
Query: 621 DKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDT-----CEDGYFALEK 675
+ GC C C ++S +C Q G C C+ GG C C D +
Sbjct: 473 --ASGQGCEPCACDPHNSLSP--QCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVA 528
Query: 676 SNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENNY 721
+ GC+ C CD G C SG C CR + G C + + Y
Sbjct: 529 T---GCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGY 571
Score = 124 bits (311), Expect = 2e-27
Identities = 67/215 (31%), Positives = 97/215 (45%), Gaps = 27/215 (12%)
Query: 1264 LPCECHPTGAT-GPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCGR------ 1316
+ CEC P GA G C P GQC C+ +V G +C C G G P C R
Sbjct: 377 ISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNIL 436
Query: 1317 -----RLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPEC 1371
C+E +G+C C P V P+C+ C + + GCE C C ++ P+C
Sbjct: 437 GSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLS---PQC 493
Query: 1372 DRDSGQCRCKPRITGRQCDRCASGFYRFPE---------CVPCNCNRDGTEPGVCDPGTG 1422
++ +GQC C+ G C A+ + P+ C C+C+ GTE CD +G
Sbjct: 494 NQFTGQCPCREGFGGLMCS--AAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASG 551
Query: 1423 ACLCKENVEGTECNVCREGSFHLDPANLKGCTSCF 1457
CLC+ + G C+ C+ G + P + C CF
Sbjct: 552 RCLCRPGLTGPRCDQCQRGYCNRYPVCV-ACHPCF 585
Score = 99.8 bits (247), Expect = 4e-20
Identities = 74/237 (31%), Positives = 95/237 (40%), Gaps = 40/237 (16%)
Query: 1258 FYHKGALPCECHPTGATGPHCSPEGGQ-CPCQPNVIGRQCTRCATGHYGFP--------- 1307
F H A C P + GP + + C CQ N G C RCA + P
Sbjct: 251 FCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDA 310
Query: 1308 -RCKPCSCG--RRLCE-----------EMTGQC-RCPPRTVRPQCEVCETHSF-SFHPMA 1351
C+ C C C G C C T CE C+ H F + P A
Sbjct: 311 HECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGA 370
Query: 1352 G----CEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGF----YRFPE-C 1402
C C C G + A CD +GQC CK + G +CD C GF Y P+ C
Sbjct: 371 SIQETCISCECDPDGAVPGA--PCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGC 428
Query: 1403 VPCNCNRDGTEPGV-CDPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFC 1458
C+CN G+ + CD +G CLC NV G +C+ C +H A+ +GC C C
Sbjct: 429 HRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQC--APYHWKLASGQGCEPCAC 483
Score = 95.9 bits (237), Expect = 6e-19
Identities = 60/197 (30%), Positives = 87/197 (44%), Gaps = 34/197 (17%)
Query: 1652 EICACPPAYAGDSCQGCSPGY----YRDHKGLYTGRCVPCNCNGHSNQCQDG-------- 1699
++C C AG +C+ C+P Y +R +G C C+CNGHS C
Sbjct: 277 DVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQ 336
Query: 1700 ---SGICVNCQHNTAGEHCERCQEGYY-----GNAVHGSCRACPCPHTNSFATGCVVNGG 1751
G+C NC+ +T G++CERCQ Y+ G ++ +C +C C + G +
Sbjct: 337 GAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCEC-DPDGAVPGAPCDPV 395
Query: 1752 DVRCSCKAGYTGTQCERCAPGYFG----NPQKFGGSCQPCSCNSNGQLGS--CHPLTGDC 1805
+C CK G +C+ C PG+ G NPQ C C CN G C +G C
Sbjct: 396 TGQCVCKEHVQGERCDLCKPGFTGLTYANPQ----GCHRCDCNILGSRRDMPCDEESGRC 451
Query: 1806 INQEPKDSSPAEECDDC 1822
+ P P +CD C
Sbjct: 452 LCL-PNVVGP--KCDQC 465
Score = 84.3 bits (207), Expect = 2e-15
Identities = 150/716 (20%), Positives = 272/716 (37%), Gaps = 85/716 (11%)
Query: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGR-CVPCNCNGHSN---QCQDGSGICVNCQHN 1709
C C P G C C+P +++ L +G+ C PC C+ H++ QC +G C C+
Sbjct: 451 CLCLPNVVGPKCDQCAPYHWK----LASGQGCEPCACDPHNSLSPQCNQFTGQCP-CREG 505
Query: 1710 TAGEHCE-----RCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGT 1764
G C +C + YG+ G CRAC C + GC G RC C+ G TG
Sbjct: 506 FGGLMCSAAAIRQCPDRTYGDVATG-CRACDCDFRGTEGPGCDKASG--RCLCRPGLTGP 562
Query: 1765 QCERCAPGYFGNPQKFGGSCQPC-----------------SCNSNGQLGSCHPLTGDCIN 1807
+C++C GY N +C PC N+ L S L +
Sbjct: 563 RCDQCQRGYC-NRYPVCVACHPCFQTYDADLREQALRFGRLRNATASLWSGPGLEDRGLA 621
Query: 1808 QEPKDS-SPAEECDDCDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQ 1866
D+ S E+ S ++A + + ++ LQGL L E+ +
Sbjct: 622 SRILDAKSKIEQIRAVLSSPAVTEQEVAQVASAILSLRRTLQGLQLDLPLEEETLSL--- 678
Query: 1867 AKDLRNQLLNYRSAISNHGSKIEGLER-ELTDLNQEFETLQEKAQVNSRKAQTLNNNVNR 1925
+DL + ++ ++ + K E E+ D + F L + +++ AQ +
Sbjct: 679 PRDLESLDRSFNGLLTMYQRKREQFEKISSADPSGAFRMLSTAYEQSAQAAQ-------Q 731
Query: 1926 ATQSAKELDVKIKNVIRNVHILLKQISGTDGEGNNVPSGDFSREWAEAQRMMRELRNRNF 1985
+ S++ LD ++++ R L++Q G G G+ P R + + N+
Sbjct: 732 VSDSSRLLD-QLRDSRREAERLVRQAGGGGGTGS--PKLVALRLEMSSLPDLTPTFNKLC 788
Query: 1986 GKHLREA--------EADKRESQLLLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSD 2037
G + A E +++ G +A + + L + A+L
Sbjct: 789 GNSRQMACTPISCPGELCPQDNGTACGSRCRGVLPRAGGAFLMAGQVAEQLRGFNAQLQR 848
Query: 2038 LRARLQEAAAQAKQANGLNQENERALGAIQRQVKE----INSLQSDFTKYLTTADS---- 2089
R ++ A A Q Q E + A + Q++E L +LT D+
Sbjct: 849 TRQMIRAAEESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAAT 908
Query: 2090 --SLLQTNIALQLMEKS------QKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEE 2141
+ + +AL L S E + +AA L LS ++++R+ + EE
Sbjct: 909 IQEVSEAVLALWLPTDSATVLQKMNEIQAIAARLPNVDLVLSQTKQDIARARRLQAEAEE 968
Query: 2142 AEKHARSLQELAKQLEEIKRN-ASGDELVRCAVDAATAYENILNAIKAAEDAANRAASAS 2200
A A +++ Q+E++ N G ++ A D L I+ + +
Sbjct: 969 ARSRAHAVE---GQVEDVVGNLRQGTVALQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPA 1025
Query: 2201 ESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKE 2260
E + ++ K+ + ++L ++A+ + Q A +Q L+ E
Sbjct: 1026 EKLVTSMTKQ-----LGDFWTRMEELRHQARQQGAEAVQAQQLAEGASEQALS-AQEGFE 1079
Query: 2261 VIDTNLTTLRDGL-HGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVER 2315
I L+D L G+ A I S K+ + T E++D + ++ ++ R
Sbjct: 1080 RIKQKYAELKDRLGQSSMLGEQGARIQSVKTEAEELFGETMEMMDRMKDMELELLR 1135
Score = 72.4 bits (176), Expect = 7e-12
Identities = 54/170 (31%), Positives = 73/170 (42%), Gaps = 40/170 (23%)
Query: 1687 CNCNGHSNQCQDGSG-------------ICVNCQHNTAGEHCERCQEGY--------YGN 1725
C C+GH+++C G +CV CQHNTAG +CERC Y G
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERCAPFYNNRPWRPAEGQ 308
Query: 1726 AVHGSCRACPC-PHTNS-------FATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNP 1777
H C+ C C H+ + FA GG V +C+ G CERC YF N
Sbjct: 309 DAH-ECQRCDCNGHSETCHFDPAVFAASQGAYGG-VCDNCRDHTEGKNCERCQLHYFRNR 366
Query: 1778 Q---KFGGSCQPCSCNSNGQL--GSCHPLTGDCINQEPKDSSPAEECDDC 1822
+ +C C C+ +G + C P+TG C+ K+ E CD C
Sbjct: 367 RPGASIQETCISCECDPDGAVPGAPCDPVTGQCV---CKEHVQGERCDLC 413
Score = 61.6 bits (148), Expect = 1e-08
Identities = 32/109 (29%), Positives = 49/109 (44%), Gaps = 13/109 (11%)
Query: 1261 KGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCT-----RCATGHYG--FPRCKPCS 1313
+G PC C P + P C+ GQCPC+ G C+ +C YG C+ C
Sbjct: 476 QGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACD 535
Query: 1314 CGRR-----LCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPM-AGCEGC 1356
C R C++ +G+C C P P+C+ C+ + +P+ C C
Sbjct: 536 CDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPC 584
Score = 42.0 bits (97), Expect = 0.010
Identities = 31/114 (27%), Positives = 45/114 (39%), Gaps = 22/114 (19%)
Query: 631 CKCH--------KAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYF-----ALEKSN 677
C CH K G +G Q C C+ + G +C+ C Y E +
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQD 309
Query: 678 YFGCQGCQCD-------IGGALSSMCSGP-SGVCQ-CREHVVGKVCQRPENNYY 722
CQ C C+ A+ + G GVC CR+H GK C+R + +Y+
Sbjct: 310 AHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYF 363
>gi|189083719 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 269 bits (688), Expect = 3e-71
Identities = 186/593 (31%), Positives = 262/593 (44%), Gaps = 97/593 (16%)
Query: 62 ATATCGERGPGEGRPQPELYCKLVGGPTAPGSGHTIQGQF-CDYCNSEDPRK--AHPVTN 118
A++TCG +PE YC G + Q C C+S P +H V N
Sbjct: 43 ASSTCG-------LTKPETYCTQYG-----------EWQMKCCKCDSRQPHNYYSHRVEN 84
Query: 119 AID--GSERWWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVD 176
G RWWQS N V+L LDL + F + ++++F P P ++ERS D
Sbjct: 85 VASSSGPMRWWQSQ-----NDVNPVSLQLDLDRRFQLQEVMMEF-QGPMPAGMLIERSSD 138
Query: 177 FGSTYSPWQYFAHSKVDCLKEFGREANMAVTRDDDVLCVTEYSRIVPLENGEVV----VS 232
FG T+ +QY A DC F R DV C + R NG V +
Sbjct: 139 FGKTWRVYQYLA---ADCTSTFPRVRQGRPQSWQDVRCQSLPQRPNARLNGGKVQLNLMD 195
Query: 233 LINGRPGAKNFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDPTVTRRYYYSIKD 292
L++G P T S ++E + TN+R+ F R L + + P+ YY++
Sbjct: 196 LVSGIPA----TQSQKIQEVGEITNLRVNFTR----LAPVPQRGYHPPSA----YYAVSQ 243
Query: 293 ISIGGQCVCNGHAEVCNIN-----NPEKLFR----CECQHHTCGETCDRCCTGYNQRRWR 343
+ + G C C+GHA+ C P + C CQH+T G C+RC YN R WR
Sbjct: 244 LRLQGSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWR 303
Query: 344 PAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCE 403
PA + +HEC+ C+C+GH+ C++DP V +QG Y GGVC NC+ +T G NCE
Sbjct: 304 PAEGQDAHECQRCDCNGHSETCHFDPAV-----FAASQGAY--GGVCDNCRDHTEGKNCE 356
Query: 404 QCAKGYYRPYGVPVDAPDGCIPCSCDPEHA---DGCEQGSGRCHCKPNFHGDNCEKCAIG 460
+C Y+R + CI C CDP+ A C+ +G+C CK + G+ C+ C G
Sbjct: 357 RCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPG 416
Query: 461 YYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEI-CDAH-GRCLCRPGVEGP 518
+ + + P CDCN+ G ++ CD GRCLC P V GP
Sbjct: 417 FTGLTY---------ANPQG-------CHRCDCNILGSRRDMPCDEESGRCLCLPNVVGP 460
Query: 519 RCDTCRSGFYSFPI---CQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCD-----RCL 570
+CD C + C+ C C S C+ TGQC CR G G C +C
Sbjct: 461 KCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCP 520
Query: 571 SGAYDFPHCQGSSSACDPAGT----INSNLGYCQCKLHVEGPTCSRCKLLYWN 619
Y + CD GT + G C C+ + GP C +C+ Y N
Sbjct: 521 DRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCN 573
Score = 129 bits (324), Expect = 5e-29
Identities = 99/346 (28%), Positives = 131/346 (37%), Gaps = 74/346 (21%)
Query: 426 CSCDPEHADGCEQGSGR-------------CHCKPNFHGDNCEKCAIGYYNFPFCLRIPI 472
C C HAD C G C C+ N G NCE+CA Y N P+
Sbjct: 250 CFCHG-HADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPW------ 302
Query: 473 FPVSTPSSEDPVAGDIKGCDCN---------------LEGVLPEICDAHGRCLCRPGVEG 517
+E A + + CDCN +G +CD CR EG
Sbjct: 303 -----RPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDN-----CRDHTEG 352
Query: 518 PRCDTC--------RSGFYSFPICQACWCSALGSYQ-MPCSSVTGQCECRPGVTGQRCDR 568
C+ C R G C +C C G+ PC VTGQC C+ V G+RCD
Sbjct: 353 KNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDL 412
Query: 569 CLSG--AYDFPHCQGSSSA-CDPAGT-----INSNLGYCQCKLHVEGPTCSRCKLLYWNL 620
C G + + QG C+ G+ + G C C +V GP C +C +W L
Sbjct: 413 CKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKL 472
Query: 621 DKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDT-----CEDGYFALEK 675
+ GC C C ++S +C Q G C C+ GG C C D +
Sbjct: 473 --ASGQGCEPCACDPHNSLSP--QCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVA 528
Query: 676 SNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENNY 721
+ GC+ C CD G C SG C CR + G C + + Y
Sbjct: 529 T---GCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGY 571
Score = 124 bits (311), Expect = 2e-27
Identities = 67/215 (31%), Positives = 97/215 (45%), Gaps = 27/215 (12%)
Query: 1264 LPCECHPTGAT-GPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCGR------ 1316
+ CEC P GA G C P GQC C+ +V G +C C G G P C R
Sbjct: 377 ISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNIL 436
Query: 1317 -----RLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPEC 1371
C+E +G+C C P V P+C+ C + + GCE C C ++ P+C
Sbjct: 437 GSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLS---PQC 493
Query: 1372 DRDSGQCRCKPRITGRQCDRCASGFYRFPE---------CVPCNCNRDGTEPGVCDPGTG 1422
++ +GQC C+ G C A+ + P+ C C+C+ GTE CD +G
Sbjct: 494 NQFTGQCPCREGFGGLMCS--AAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASG 551
Query: 1423 ACLCKENVEGTECNVCREGSFHLDPANLKGCTSCF 1457
CLC+ + G C+ C+ G + P + C CF
Sbjct: 552 RCLCRPGLTGPRCDQCQRGYCNRYPVCV-ACHPCF 585
Score = 99.8 bits (247), Expect = 4e-20
Identities = 74/237 (31%), Positives = 95/237 (40%), Gaps = 40/237 (16%)
Query: 1258 FYHKGALPCECHPTGATGPHCSPEGGQ-CPCQPNVIGRQCTRCATGHYGFP--------- 1307
F H A C P + GP + + C CQ N G C RCA + P
Sbjct: 251 FCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDA 310
Query: 1308 -RCKPCSCG--RRLCE-----------EMTGQC-RCPPRTVRPQCEVCETHSF-SFHPMA 1351
C+ C C C G C C T CE C+ H F + P A
Sbjct: 311 HECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGA 370
Query: 1352 G----CEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGF----YRFPE-C 1402
C C C G + A CD +GQC CK + G +CD C GF Y P+ C
Sbjct: 371 SIQETCISCECDPDGAVPGA--PCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGC 428
Query: 1403 VPCNCNRDGTEPGV-CDPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFC 1458
C+CN G+ + CD +G CLC NV G +C+ C +H A+ +GC C C
Sbjct: 429 HRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQC--APYHWKLASGQGCEPCAC 483
Score = 95.9 bits (237), Expect = 6e-19
Identities = 60/197 (30%), Positives = 87/197 (44%), Gaps = 34/197 (17%)
Query: 1652 EICACPPAYAGDSCQGCSPGY----YRDHKGLYTGRCVPCNCNGHSNQCQDG-------- 1699
++C C AG +C+ C+P Y +R +G C C+CNGHS C
Sbjct: 277 DVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQ 336
Query: 1700 ---SGICVNCQHNTAGEHCERCQEGYY-----GNAVHGSCRACPCPHTNSFATGCVVNGG 1751
G+C NC+ +T G++CERCQ Y+ G ++ +C +C C + G +
Sbjct: 337 GAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCEC-DPDGAVPGAPCDPV 395
Query: 1752 DVRCSCKAGYTGTQCERCAPGYFG----NPQKFGGSCQPCSCNSNGQLGS--CHPLTGDC 1805
+C CK G +C+ C PG+ G NPQ C C CN G C +G C
Sbjct: 396 TGQCVCKEHVQGERCDLCKPGFTGLTYANPQ----GCHRCDCNILGSRRDMPCDEESGRC 451
Query: 1806 INQEPKDSSPAEECDDC 1822
+ P P +CD C
Sbjct: 452 LCL-PNVVGP--KCDQC 465
Score = 84.3 bits (207), Expect = 2e-15
Identities = 150/716 (20%), Positives = 272/716 (37%), Gaps = 85/716 (11%)
Query: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGR-CVPCNCNGHSN---QCQDGSGICVNCQHN 1709
C C P G C C+P +++ L +G+ C PC C+ H++ QC +G C C+
Sbjct: 451 CLCLPNVVGPKCDQCAPYHWK----LASGQGCEPCACDPHNSLSPQCNQFTGQCP-CREG 505
Query: 1710 TAGEHCE-----RCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGT 1764
G C +C + YG+ G CRAC C + GC G RC C+ G TG
Sbjct: 506 FGGLMCSAAAIRQCPDRTYGDVATG-CRACDCDFRGTEGPGCDKASG--RCLCRPGLTGP 562
Query: 1765 QCERCAPGYFGNPQKFGGSCQPC-----------------SCNSNGQLGSCHPLTGDCIN 1807
+C++C GY N +C PC N+ L S L +
Sbjct: 563 RCDQCQRGYC-NRYPVCVACHPCFQTYDADLREQALRFGRLRNATASLWSGPGLEDRGLA 621
Query: 1808 QEPKDS-SPAEECDDCDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQ 1866
D+ S E+ S ++A + + ++ LQGL L E+ +
Sbjct: 622 SRILDAKSKIEQIRAVLSSPAVTEQEVAQVASAILSLRRTLQGLQLDLPLEEETLSL--- 678
Query: 1867 AKDLRNQLLNYRSAISNHGSKIEGLER-ELTDLNQEFETLQEKAQVNSRKAQTLNNNVNR 1925
+DL + ++ ++ + K E E+ D + F L + +++ AQ +
Sbjct: 679 PRDLESLDRSFNGLLTMYQRKREQFEKISSADPSGAFRMLSTAYEQSAQAAQ-------Q 731
Query: 1926 ATQSAKELDVKIKNVIRNVHILLKQISGTDGEGNNVPSGDFSREWAEAQRMMRELRNRNF 1985
+ S++ LD ++++ R L++Q G G G+ P R + + N+
Sbjct: 732 VSDSSRLLD-QLRDSRREAERLVRQAGGGGGTGS--PKLVALRLEMSSLPDLTPTFNKLC 788
Query: 1986 GKHLREA--------EADKRESQLLLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSD 2037
G + A E +++ G +A + + L + A+L
Sbjct: 789 GNSRQMACTPISCPGELCPQDNGTACGSRCRGVLPRAGGAFLMAGQVAEQLRGFNAQLQR 848
Query: 2038 LRARLQEAAAQAKQANGLNQENERALGAIQRQVKE----INSLQSDFTKYLTTADS---- 2089
R ++ A A Q Q E + A + Q++E L +LT D+
Sbjct: 849 TRQMIRAAEESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAAT 908
Query: 2090 --SLLQTNIALQLMEKS------QKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEE 2141
+ + +AL L S E + +AA L LS ++++R+ + EE
Sbjct: 909 IQEVSEAVLALWLPTDSATVLQKMNEIQAIAARLPNVDLVLSQTKQDIARARRLQAEAEE 968
Query: 2142 AEKHARSLQELAKQLEEIKRN-ASGDELVRCAVDAATAYENILNAIKAAEDAANRAASAS 2200
A A +++ Q+E++ N G ++ A D L I+ + +
Sbjct: 969 ARSRAHAVE---GQVEDVVGNLRQGTVALQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPA 1025
Query: 2201 ESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKE 2260
E + ++ K+ + ++L ++A+ + Q A +Q L+ E
Sbjct: 1026 EKLVTSMTKQ-----LGDFWTRMEELRHQARQQGAEAVQAQQLAEGASEQALS-AQEGFE 1079
Query: 2261 VIDTNLTTLRDGL-HGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVER 2315
I L+D L G+ A I S K+ + T E++D + ++ ++ R
Sbjct: 1080 RIKQKYAELKDRLGQSSMLGEQGARIQSVKTEAEELFGETMEMMDRMKDMELELLR 1135
Score = 72.4 bits (176), Expect = 7e-12
Identities = 54/170 (31%), Positives = 73/170 (42%), Gaps = 40/170 (23%)
Query: 1687 CNCNGHSNQCQDGSG-------------ICVNCQHNTAGEHCERCQEGY--------YGN 1725
C C+GH+++C G +CV CQHNTAG +CERC Y G
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERCAPFYNNRPWRPAEGQ 308
Query: 1726 AVHGSCRACPC-PHTNS-------FATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNP 1777
H C+ C C H+ + FA GG V +C+ G CERC YF N
Sbjct: 309 DAH-ECQRCDCNGHSETCHFDPAVFAASQGAYGG-VCDNCRDHTEGKNCERCQLHYFRNR 366
Query: 1778 Q---KFGGSCQPCSCNSNGQL--GSCHPLTGDCINQEPKDSSPAEECDDC 1822
+ +C C C+ +G + C P+TG C+ K+ E CD C
Sbjct: 367 RPGASIQETCISCECDPDGAVPGAPCDPVTGQCV---CKEHVQGERCDLC 413
Score = 61.6 bits (148), Expect = 1e-08
Identities = 32/109 (29%), Positives = 49/109 (44%), Gaps = 13/109 (11%)
Query: 1261 KGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCT-----RCATGHYG--FPRCKPCS 1313
+G PC C P + P C+ GQCPC+ G C+ +C YG C+ C
Sbjct: 476 QGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACD 535
Query: 1314 CGRR-----LCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPM-AGCEGC 1356
C R C++ +G+C C P P+C+ C+ + +P+ C C
Sbjct: 536 CDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPC 584
Score = 42.0 bits (97), Expect = 0.010
Identities = 31/114 (27%), Positives = 45/114 (39%), Gaps = 22/114 (19%)
Query: 631 CKCH--------KAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYF-----ALEKSN 677
C CH K G +G Q C C+ + G +C+ C Y E +
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQD 309
Query: 678 YFGCQGCQCD-------IGGALSSMCSGP-SGVCQ-CREHVVGKVCQRPENNYY 722
CQ C C+ A+ + G GVC CR+H GK C+R + +Y+
Sbjct: 310 AHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYF 363
>gi|167614504 laminin, beta 1 precursor [Homo sapiens]
Length = 1786
Score = 266 bits (680), Expect = 3e-70
Identities = 183/599 (30%), Positives = 279/599 (46%), Gaps = 99/599 (16%)
Query: 21 LLLLVLRVLPACGATAR--DP----GAAAGLSLHPTYFNL--AEAARIWATATCGERGPG 72
L LL L C A R +P G A G S +P +L A ++ T+TCG
Sbjct: 4 LQLLAFSFLALCRARVRAQEPEFSYGCAEG-SCYPATGDLLIGRAQKLSVTSTCGLH--- 59
Query: 73 EGRPQPELYCKLVGGPTAPGSGHTIQGQFCDYCNSEDPRK------AHPVTNAI-----D 121
+PE YC + H + + C CNS+DP +H + N + +
Sbjct: 60 ----KPEPYCIV---------SHLQEDKKCFICNSQDPYHETLNPDSHLIENVVTTFAPN 106
Query: 122 GSERWWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVDFGSTY 181
+ WWQS +G + V + LDL FH ++++ F RP ++ERS DFG T+
Sbjct: 107 RLKIWWQS---ENGVE--NVTIQLDLEAEFHFTHLIMTFKTF-RPAAMLIERSSDFGKTW 160
Query: 182 SPWQYFAHSKVDCLKEFGREANMAVTRDDDVLCVTEYSRIVPLENGEVVVSLINGRPGAK 241
++YFA+ DC F + + + DD++C + YS I P GEV+ ++ P K
Sbjct: 161 GVYRYFAY---DCEASFPGISTGPMKKVDDIICDSRYSDIEPSTEGEVIFRALD--PAFK 215
Query: 242 -NFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDPTVTRRYYYSIKDISIGGQCV 300
+S ++ K TN+R++F++ +TL +L+ + +YYY++ D+ + G C
Sbjct: 216 IEDPYSPRIQNLLKITNLRIKFVKLHTLGDNLLDSRME---IREKYYYAVYDMVVRGNCF 272
Query: 301 CNGHAEVC----NINNPEKLF---RCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHEC 353
C GHA C N + C C+H+T G C+ C Y+ WRPA S+ C
Sbjct: 273 CYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNAC 332
Query: 354 EACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPY 413
+ CNC+ H+ +C++D V +++ GGVC +CQHNT G NCEQC YY+
Sbjct: 333 KKCNCNEHSISCHFDMAVYLATGNVS-------GGVCDDCQHNTMGRNCEQCKPFYYQHP 385
Query: 414 GVPVDAPDGCIPCSCDPEHADG---CEQG--------SGRCHCKPNFHGDNCEKCAIGYY 462
+ P+ C C+CDP + C+ +G+C CK N G++C+ C G+Y
Sbjct: 386 ERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFY 445
Query: 463 NFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLP--EICDAH-GRCLCRPGVEGPR 519
+ SSEDP K C CN G +P CD+ G C C+ V G
Sbjct: 446 DL--------------SSEDPFG--CKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQH 489
Query: 520 CDTCRSGFYSFPI----CQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAY 574
CD C + C+ C C G+ C + +GQC CRP + G++C+ G Y
Sbjct: 490 CDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYY 548
Score = 175 bits (444), Expect = 6e-43
Identities = 130/448 (29%), Positives = 170/448 (37%), Gaps = 114/448 (25%)
Query: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 358
C C+ V NP +C C CDRC G+ W C+ C C
Sbjct: 821 CECHLQGSVNAFCNPVT-GQCHCFQGVYARQCDRCLPGH---------WGFP-SCQPCQC 869
Query: 359 HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPV- 417
+GHA +C DP G C+NCQ T G NCE+C GYY G P+
Sbjct: 870 NGHADDC--DPVT----------------GECLNCQDYTMGHNCERCLAGYY---GDPII 908
Query: 418 DAPDGCIPCSCDPEHADGCEQGSGRCH-----------CKPNFHGDNCEKCAIGYYNFPF 466
+ D C PC C P+ D Q + C+ C P + G C+ CA GY+ P
Sbjct: 909 GSGDHCRPCPC-PDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNP- 966
Query: 467 CLRIPIFPVSTPSSEDPVAGDIKGCDC--NLEGVLPEICDAH-GRCL-CRPGVEGPRCDT 522
V G + C C N++ PE CD GRCL C EG C
Sbjct: 967 ---------------SEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQF 1011
Query: 523 CRSGFYSFPI---CQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHC 579
CR G+Y + C+ C C+ LG+ Q HC
Sbjct: 1012 CRFGYYGDALQQDCRKCVCNYLGTVQ-------------------------------EHC 1040
Query: 580 QGSSSACDPAGTINSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTV 639
GS CD A G C C +V G C RC W L + +GC C C+ A +
Sbjct: 1041 NGSDCQCDKA------TGQCLCLPNVIGQNCDRCAPNTWQL--ASGTGCDPCNCNAAHSF 1092
Query: 640 SGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGP 699
+ C + G C C GG +C C++ ++ C+ C CD G + C
Sbjct: 1093 GPS--CNEFTGQCQCMPGFGGRTCSECQELFWGDPDVE---CRACDCDPRGIETPQCDQS 1147
Query: 700 SGVCQCREHVVGKVCQRPENNY--YFPD 725
+G C C E V G C + Y FPD
Sbjct: 1148 TGQCVCVEGVEGPRCDKCTRGYSGVFPD 1175
Score = 168 bits (425), Expect = 9e-41
Identities = 89/276 (32%), Positives = 127/276 (46%), Gaps = 43/276 (15%)
Query: 506 HGRCLCRPGVEGPRCDTCRSGFYSFP----------ICQACWC---SALGSYQMPCSSVT 552
HG C+CR +G C+ C ++ P C+ C C S + M T
Sbjct: 295 HGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLAT 354
Query: 553 GQC------ECRPGVTGQRCDRCLSGAYDFPH--------CQGSSSACDPAGTINSNL-- 596
G +C+ G+ C++C Y P C+ + CDPAG+ N +
Sbjct: 355 GNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCT--CDPAGSQNEGICD 412
Query: 597 -----------GYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGEC 645
G C+CKL+VEG C CK +++L E+P GC C C+ GT+ G C
Sbjct: 413 SYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPC 472
Query: 646 RQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQC 705
G C+CK V G CD C ++ L ++ GC+ C CD+GGAL++ C SG C C
Sbjct: 473 DSETGHCYCKRLVTGQHCDQCLPEHWGL-SNDLDGCRPCDCDLGGALNNSCFAESGQCSC 531
Query: 706 REHVVGKVCQRPENNYYFPDLHHMKYEIEDGSTPNG 741
R H++G+ C E YYF L H YE E+ + G
Sbjct: 532 RPHMIGRQCNEVEPGYYFATLDHYLYEAEEANLGPG 567
Score = 147 bits (370), Expect = 2e-34
Identities = 85/238 (35%), Positives = 104/238 (43%), Gaps = 23/238 (9%)
Query: 1241 PQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCA 1300
P R C A F G PCECH G+ C+P GQC C V RQC RC
Sbjct: 796 PNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCL 855
Query: 1301 TGHYGFPRCKPCSCGRRL--CEEMTGQC-RCPPRTVRPQCEVCETHSFSFHPMAG----C 1353
GH+GFP C+PC C C+ +TG+C C T+ CE C + P+ G C
Sbjct: 856 PGHWGFPSCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCLAGYYG-DPIIGSGDHC 914
Query: 1354 EGCNC-----SRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFP-----ECV 1403
C C S R + + C C P G +CD CASG++ P C
Sbjct: 915 RPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQ 974
Query: 1404 PCNC--NRDGTEPGVCDPGTGACL-CKENVEGTECNVCREGSFHLDPANLKGCTSCFC 1458
PC C N D T+P CD TG CL C + EG C CR G + A + C C C
Sbjct: 975 PCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFG--YYGDALQQDCRKCVC 1030
Score = 145 bits (367), Expect = 5e-34
Identities = 95/324 (29%), Positives = 135/324 (41%), Gaps = 58/324 (17%)
Query: 424 IPCSCDPEHA--DGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSE 481
+ C CDP+ + C+ G+C C+PN G C +CA G + F PS
Sbjct: 771 LACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGF------------GPSG- 817
Query: 482 DPVAGDIKGCDCNLEGVLPEICD-AHGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSA 540
K C+C+L+G + C+ G+C C GV +CD C G + FP CQ C C+
Sbjct: 818 ------CKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCN- 870
Query: 541 LGSYQMPCSSVTGQC-ECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDP--------AGT 591
+ C VTG+C C+ G C+RCL+G Y P GS C P +G
Sbjct: 871 --GHADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDP-IIGSGDHCRPCPCPDGPDSGR 927
Query: 592 INSNLGY---------CQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGT 642
+ Y C C G C C Y+ E C C+CH +
Sbjct: 928 QFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDP 987
Query: 643 GECRQGDGDC-HCKSHVGGDSCDTCEDGYF--ALEKSNYFGCQGCQCDIGGALSSMCSG- 698
C + G C C H G+ C C GY+ AL++ C+ C C+ G + C+G
Sbjct: 988 EACDKETGRCLKCLYHTEGEHCQFCRFGYYGDALQQD----CRKCVCNYLGTVQEHCNGS 1043
Query: 699 ------PSGVCQCREHVVGKVCQR 716
+G C C +V+G+ C R
Sbjct: 1044 DCQCDKATGQCLCLPNVIGQNCDR 1067
Score = 143 bits (361), Expect = 2e-33
Identities = 86/251 (34%), Positives = 115/251 (45%), Gaps = 35/251 (13%)
Query: 1232 CGKNSFYLDPQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNV 1291
C +NS + + C+N S+ A H+ L CEC P G+ C P GGQC C+PNV
Sbjct: 739 CLENSRSVVKTPMTDVCRNIIFSISALLHQTGLACECDPQGSLSSVCDPNGGQCQCRPNV 798
Query: 1292 IGRQCTRCATGHYGF--PRCKPCSCG-----RRLCEEMTGQCRCPPRTVRPQCEVCETHS 1344
+GR C RCA G +GF CKPC C C +TGQC C QC+ C
Sbjct: 799 VGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGH 858
Query: 1345 FSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQC-RCKPRITGRQCDRCASGFYRFP--- 1400
+ F C+ C C+ +CD +G+C C+ G C+RC +G+Y P
Sbjct: 859 WGF---PSCQPCQCNGHA------DDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIG 909
Query: 1401 ---ECVPCNCNRDGTEPG-------VCDPGT--GACLCKENVEGTECNVCREGSFHLDPA 1448
C PC C DG + G DP T AC+C G+ C+ C G F +P+
Sbjct: 910 SGDHCRPCPC-PDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFG-NPS 967
Query: 1449 NLKG-CTSCFC 1458
+ G C C C
Sbjct: 968 EVGGSCQPCQC 978
Score = 138 bits (348), Expect = 8e-32
Identities = 69/165 (41%), Positives = 88/165 (53%), Gaps = 18/165 (10%)
Query: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGE 1713
C C C C PG H G + C PC CNGH++ C +G C+NCQ T G
Sbjct: 840 CHCFQGVYARQCDRCLPG----HWGFPS--CQPCQCNGHADDCDPVTGECLNCQDYTMGH 893
Query: 1714 HCERCQEGYYGNAVHGS---CRACPCP----HTNSFATGCVVNGGDVR--CSCKAGYTGT 1764
+CERC GYYG+ + GS CR CPCP FA C + ++ C C GY G+
Sbjct: 894 NCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGS 953
Query: 1765 QCERCAPGYFGNPQKFGGSCQPCSCNSN---GQLGSCHPLTGDCI 1806
+C+ CA GYFGNP + GGSCQPC C++N +C TG C+
Sbjct: 954 RCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCL 998
Score = 132 bits (333), Expect = 4e-30
Identities = 89/253 (35%), Positives = 110/253 (43%), Gaps = 29/253 (11%)
Query: 491 CDCNLEGVLPEICDAHG-RCLCRPGVEGPRCDTCRSGFYSFPI--CQACWCSALGSYQMP 547
C+C+ +G L +CD +G +C CRP V G C+ C G + F C+ C C GS
Sbjct: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAF 832
Query: 548 CSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQ-----GSSSACDPAGTINSNLGYC-QC 601
C+ VTGQC C GV ++CDRCL G + FP CQ G + CDP G C C
Sbjct: 833 CNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCNGHADDCDPV------TGECLNC 886
Query: 602 KLHVEGPTCSRCKLLYWNLDKENPSG--CSECKCHKAGTVSGTGECRQGDGD-------C 652
+ + G C RC Y+ D SG C C C G SG R D C
Sbjct: 887 QDYTMGHNCERCLAGYYG-DPIIGSGDHCRPCPC-PDGPDSGRQFARSCYQDPVTLQLAC 944
Query: 653 HCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQC--DIGGALSSMCSGPSGVC-QCREHV 709
C G CD C GYF CQ CQC +I C +G C +C H
Sbjct: 945 VCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHT 1004
Query: 710 VGKVCQRPENNYY 722
G+ CQ YY
Sbjct: 1005 EGEHCQFCRFGYY 1017
Score = 131 bits (329), Expect = 1e-29
Identities = 82/261 (31%), Positives = 113/261 (43%), Gaps = 38/261 (14%)
Query: 1265 PCECHPT-GATGPH-CSPEGGQC-PCQPNVIGRQCTRCATGHYGFPR---CKPCSCGRR- 1317
PC+CH T P C E G+C C + G C C G+YG C+ C C
Sbjct: 975 PCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDALQQDCRKCVCNYLG 1034
Query: 1318 -----------LCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEA 1366
C++ TGQC C P + C+ C +++ GC+ CNC+ +
Sbjct: 1035 TVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLASGTGCDPCNCNAAHSFG- 1093
Query: 1367 AMPECDRDSGQCRCKPRITGRQCDRCASGFYRFP--ECVPCNCNRDGTEPGVCDPGTGAC 1424
P C+ +GQC+C P GR C C F+ P EC C+C+ G E CD TG C
Sbjct: 1094 --PSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDCDPRGIETPQCDQSTGQC 1151
Query: 1425 LCKENVEGTECNVCREGSFHLDPANLKGCTSCF-CFG--------VNNQCHS--SHKRRT 1473
+C E VEG C+ C G + P CT C CF + N+ H +
Sbjct: 1152 VCVEGVEGPRCDKCTRGYSGVFP----DCTPCHQCFALWDVIIAELTNRTHRFLEKAKAL 1207
Query: 1474 KFVDMLGWHLETADRVDIPVS 1494
K ++G + ET D V+ VS
Sbjct: 1208 KISGVIGPYRETVDSVERKVS 1228
Score = 129 bits (323), Expect = 6e-29
Identities = 165/848 (19%), Positives = 314/848 (37%), Gaps = 161/848 (18%)
Query: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQ-----CQDGSGICVNCQH 1708
C C P Y G C C+ GY+ + + G C PC C+ + + C +G C+ C +
Sbjct: 944 CVCDPGYIGSRCDDCASGYFGNPSEV-GGSCQPCQCHNNIDTTDPEACDKETGRCLKCLY 1002
Query: 1709 NTAGEHCERCQEGYYGNAVHGSCRACPC-------------------------------- 1736
+T GEHC+ C+ GYYG+A+ CR C C
Sbjct: 1003 HTEGEHCQFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIG 1062
Query: 1737 -------PHTNSFATG-----CVVNGGDV----------RCSCKAGYTGTQCERCAPGYF 1774
P+T A+G C N +C C G+ G C C ++
Sbjct: 1063 QNCDRCAPNTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFW 1122
Query: 1775 GNPQKFGGSCQPCSCNSNG-QLGSCHPLTGDCINQEPKDSSPAEEC--------DDCDSC 1825
G+P C+ C C+ G + C TG C+ E + ++C DC C
Sbjct: 1123 GDPDV---ECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPDCTPC 1179
Query: 1826 VM------TLLNDLATMGEQLRLVKSQLQGLSASAG-LLEQMRHMETQAKDLRNQLLNYR 1878
++ +L + L K++ +S G E + +E + ++++ L
Sbjct: 1180 HQCFALWDVIIAELTNRTHRF-LEKAKALKISGVIGPYRETVDSVERKVSEIKDILAQSP 1238
Query: 1879 SA--ISNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKELD-- 1934
+A + N G+ E E+ + D+ + ++ K L++ +++ +AKELD
Sbjct: 1239 AAEPLKNIGNLFEEAEKLIKDVTEMMAQVEVK----------LSDTTSQSNSTAKELDSL 1288
Query: 1935 ----VKIKNVIRNVHILLKQISGTDGEGNNVPSGDFSREWAEAQRMMRELRNRNFGKHLR 1990
+ N ++ + L+ I +D G + + EA+ + +
Sbjct: 1289 QTEAESLDNTVKELAEQLEFIKNSDIRGALDSITKYFQMSLEAEERVNASTTEPNSTVEQ 1348
Query: 1991 EAEADKRESQLLLNRIRTWQKTHQGENNGLANSIRDSLNEY------------------- 2031
A R +++ R + K Q E L + + L
Sbjct: 1349 SALMRDRVEDVMMER-ESQFKEKQEEQARLLDELAGKLQSLDLSAAAEMTCGTPPGASCS 1407
Query: 2032 EAKLSDLRARLQEAAAQA----------------KQANGLNQENERALGAIQRQVKEINS 2075
E + R E + ++A L+Q+ AL +++ K ++
Sbjct: 1408 ETECGGPNCRTDEGERKCGGPGCGGLVTVAHNAWQKAMDLDQDVLSALAEVEQLSKMVSE 1467
Query: 2076 LQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGK 2135
+ + +A+ LL+TN + M+KS +E L + + S + + A +
Sbjct: 1468 AKLRADEAKQSAEDILLKTNATKEKMDKSNEELRNLIKQIRNFLTQDSADLDSIEAVANE 1527
Query: 2136 TSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANR 2195
L E + LQ L + + E + S E++ ++ I AE
Sbjct: 1528 V-LKMEMPSTPQQLQNLTEDIRERVESLSQVEVI---------LQHSAADIARAEMLLEE 1577
Query: 2196 AASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIV 2255
A AS+SA + D+ ++A L EA+ Q ++ + A ++Q T N++
Sbjct: 1578 AKRASKSATDVKVTADMVKEA----------LEEAEKAQVAAEKAIKQADEDIQGTQNLL 1627
Query: 2256 TVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVER 2315
T + + TL + I +++ + K + + + + + ++ E
Sbjct: 1628 TSIESETAASEETLFNASQRI--SELERNVEELKRKAAQNSGEAEYIEKVVYTVKQSAED 1685
Query: 2316 IKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESI-NQQLLPLGNISDNMDRIR 2374
+K T +E +KK +N + K T + D RK E + N+ L + + ++
Sbjct: 1686 VKKTLDGELDEKYKK----VENLIAKKTEESADARRKAEMLQNEAKTLLAQANSKLQLLK 1741
Query: 2375 ELIQQARD 2382
+L ++ D
Sbjct: 1742 DLERKYED 1749
Score = 127 bits (319), Expect = 2e-28
Identities = 101/342 (29%), Positives = 133/342 (38%), Gaps = 93/342 (27%)
Query: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 358
C CNGHA+ C+ E L CQ +T G C+RC GY P H C C C
Sbjct: 867 CQCNGHADDCDPVTGECL---NCQDYTMGHNCERCLAGYYGD---PIIGSGDH-CRPCPC 919
Query: 359 -------HGHASNCYYDPDVERQQASLNTQGIYA-----------------GG------- 387
A +CY DP V Q A + G GG
Sbjct: 920 PDGPDSGRQFARSCYQDP-VTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQC 978
Query: 388 ----------------GVCINCQHNTAGVNCEQCAKGYYRPYGVPVDA-PDGCIPCSCD- 429
G C+ C ++T G +C+ C GYY DA C C C+
Sbjct: 979 HNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYG------DALQQDCRKCVCNY 1032
Query: 430 ----PEHADG----CEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSE 481
EH +G C++ +G+C C PN G NC++CA + +++ +
Sbjct: 1033 LGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQ-----------LASGTGC 1081
Query: 482 DPVAGDIKGCDCNLEGVLPEICDAH-GRCLCRPGVEGPRCDTCRSGFYSFPI--CQACWC 538
DP C+CN C+ G+C C PG G C C+ F+ P C+AC C
Sbjct: 1082 DP-------CNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDC 1134
Query: 539 SALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSG-AYDFPHC 579
G C TGQC C GV G RCD+C G + FP C
Sbjct: 1135 DPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPDC 1176
Score = 103 bits (258), Expect = 2e-21
Identities = 58/191 (30%), Positives = 84/191 (43%), Gaps = 30/191 (15%)
Query: 1282 GGQCP-CQPNVIGRQCTRCATGHYGFPR--------CKPCSC------GRRLCEEMT--- 1323
GG C CQ N +GR C +C +Y P C+ C+C +C+ T
Sbjct: 359 GGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFS 418
Query: 1324 -----GQCRCPPRTVRPQCEVCET--HSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSG 1376
GQCRC C+VC+ + S GC+ C C+ GTI P CD ++G
Sbjct: 419 TGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNP-CDSETG 477
Query: 1377 QCRCKPRITGRQCDRCASGFYRFPE----CVPCNCNRDGTEPGVCDPGTGACLCKENVEG 1432
C CK +TG+ CD+C + C PC+C+ G C +G C C+ ++ G
Sbjct: 478 HCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIG 537
Query: 1433 TECNVCREGSF 1443
+CN G +
Sbjct: 538 RQCNEVEPGYY 548
Score = 92.8 bits (229), Expect = 5e-18
Identities = 69/229 (30%), Positives = 86/229 (37%), Gaps = 48/229 (20%)
Query: 1283 GQCPCQPNVIGRQCTRCATGHYGFP----------RCKPCSCGRRLCE---EMT------ 1323
G C C+ N G C C ++ P CK C+C +M
Sbjct: 296 GHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATG 355
Query: 1324 ----GQCR-CPPRTVRPQCEVCETHSFSFHPMAG------CEGCNCSRRGTIEAAMPECD 1372
G C C T+ CE C+ + HP CE C C G+ + +
Sbjct: 356 NVSGGVCDDCQHNTMGRNCEQCKPFYYQ-HPERDIRDPNFCERCTCDPAGSQNEGICDSY 414
Query: 1373 RD------SGQCRCKPRITGRQCDRCASGFYRFPE-----CVPCNCNRDGTEPG--VCDP 1419
D +GQCRCK + G CD C GFY C C CN GT PG CD
Sbjct: 415 TDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDS 474
Query: 1420 GTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFC---FGVNNQC 1465
TG C CK V G C+ C + L +L GC C C +NN C
Sbjct: 475 ETGHCYCKRLVTGQHCDQCLPEHWGLS-NDLDGCRPCDCDLGGALNNSC 522
Score = 89.4 bits (220), Expect = 6e-17
Identities = 57/211 (27%), Positives = 82/211 (38%), Gaps = 35/211 (16%)
Query: 1654 CACPPAYAGDSCQGCSPGYY----RDHKGLYTGRCVPCNCNGHSNQCQD----------- 1698
C C G +C+ C Y+ R +G + C CNCN HS C
Sbjct: 298 CMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNV 357
Query: 1699 GSGICVNCQHNTAGEHCERCQEGYYGNAVH-----GSCRACPCPHTNS-----------F 1742
G+C +CQHNT G +CE+C+ YY + C C C S F
Sbjct: 358 SGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDF 417
Query: 1743 ATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLT 1802
+TG + +C CK G C+ C G++ + C+ C+CN G + +P
Sbjct: 418 STGLIAG----QCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCD 473
Query: 1803 GDCINQEPKDSSPAEECDDCDSCVMTLLNDL 1833
+ + K + CD C L NDL
Sbjct: 474 SETGHCYCKRLVTGQHCDQCLPEHWGLSNDL 504
Score = 88.6 bits (218), Expect = 9e-17
Identities = 51/143 (35%), Positives = 66/143 (46%), Gaps = 14/143 (9%)
Query: 1681 TGRCVPCNCNGH-SNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHT 1739
TG C+ G S+ C G C C+ N G C RC G +G G C+ C C
Sbjct: 769 TGLACECDPQGSLSSVCDPNGGQC-QCRPNVVGRTCNRCAPGTFGFGPSG-CKPCECHLQ 826
Query: 1740 NSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCH 1799
S C N +C C G QC+RC PG++G P SCQPC C NG C
Sbjct: 827 GSVNAFC--NPVTGQCHCFQGVYARQCDRCLPGHWGFP-----SCQPCQC--NGHADDCD 877
Query: 1800 PLTGDCINQEPKDSSPAEECDDC 1822
P+TG+C+N + D + C+ C
Sbjct: 878 PVTGECLNCQ--DYTMGHNCERC 898
Score = 81.3 bits (199), Expect = 2e-14
Identities = 45/154 (29%), Positives = 61/154 (39%), Gaps = 25/154 (16%)
Query: 1266 CECHPTGATGPHCSPE---------GGQCPCQPNVIGRQCTRCATGHYGFPR-----CKP 1311
C C P G+ GQC C+ NV G C C G Y CK
Sbjct: 398 CTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKS 457
Query: 1312 CSC-------GRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSF-HPMAGCEGCNCSRRGT 1363
C+C G C+ TG C C C+ C + + + GC C+C G
Sbjct: 458 CACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGA 517
Query: 1364 IEAAMPECDRDSGQCRCKPRITGRQCDRCASGFY 1397
+ + C +SGQC C+P + GRQC+ G+Y
Sbjct: 518 LNNS---CFAESGQCSCRPHMIGRQCNEVEPGYY 548
Score = 79.3 bits (194), Expect = 6e-14
Identities = 50/171 (29%), Positives = 71/171 (41%), Gaps = 27/171 (15%)
Query: 1656 CPPAYAGDSCQGCSPGYY----RDHKGLYTGRCVPCNCNGHSNQCQDGSGIC-------- 1703
C G +C+ C P YY RD + C C C+ +Q GIC
Sbjct: 365 CQHNTMGRNCEQCKPFYYQHPERDIRD--PNFCERCTCDPAGSQ---NEGICDSYTDFST 419
Query: 1704 ------VNCQHNTAGEHCERCQEGYYGNAVHG--SCRACPCPHTNSFATGCVVNGGDVRC 1755
C+ N GEHC+ C+EG+Y + C++C C + G + C
Sbjct: 420 GLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHC 479
Query: 1756 SCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQL-GSCHPLTGDC 1805
CK TG C++C P ++G G C+PC C+ G L SC +G C
Sbjct: 480 YCKRLVTGQHCDQCLPEHWGLSNDLDG-CRPCDCDLGGALNNSCFAESGQC 529
Score = 68.6 bits (166), Expect = 1e-10
Identities = 38/127 (29%), Positives = 53/127 (41%), Gaps = 10/127 (7%)
Query: 1654 CACPPAYAGDSCQGCSPGYY----RDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHN 1709
C C G+ C C G+Y D G + C P N C +G C C+
Sbjct: 426 CRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCY-CKRL 484
Query: 1710 TAGEHCERCQEGYYG--NAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCE 1767
G+HC++C ++G N + G CR C C + C G +CSC+ G QC
Sbjct: 485 VTGQHCDQCLPEHWGLSNDLDG-CRPCDCDLGGALNNSCFAESG--QCSCRPHMIGRQCN 541
Query: 1768 RCAPGYF 1774
PGY+
Sbjct: 542 EVEPGYY 548
Score = 68.6 bits (166), Expect = 1e-10
Identities = 35/103 (33%), Positives = 46/103 (44%), Gaps = 8/103 (7%)
Query: 1262 GALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFP--RCKPCSCGRR-- 1317
G PC C+ + GP C+ GQC C P GR C+ C +G P C+ C C R
Sbjct: 1080 GCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDCDPRGI 1139
Query: 1318 ---LCEEMTGQCRCPPRTVRPQCEVC-ETHSFSFHPMAGCEGC 1356
C++ TGQC C P+C+ C +S F C C
Sbjct: 1140 ETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPDCTPCHQC 1182
Score = 67.4 bits (163), Expect = 2e-10
Identities = 37/98 (37%), Positives = 50/98 (51%), Gaps = 11/98 (11%)
Query: 1727 VHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGS-CQ 1785
+H + AC C S ++ C NGG +C C+ G C RCAPG FG FG S C+
Sbjct: 766 LHQTGLACECDPQGSLSSVCDPNGG--QCQCRPNVVGRTCNRCAPGTFG----FGPSGCK 819
Query: 1786 PCSCNSNGQLGS-CHPLTGDCINQEPKDSSPAEECDDC 1822
PC C+ G + + C+P+TG C A +CD C
Sbjct: 820 PCECHLQGSVNAFCNPVTGQC---HCFQGVYARQCDRC 854
Score = 60.5 bits (145), Expect = 3e-08
Identities = 27/69 (39%), Positives = 35/69 (50%), Gaps = 7/69 (10%)
Query: 1405 CNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCREGSFHLDPA-------NLKGCTSCF 1457
C C+ G+ VCDP G C C+ NV G CN C G+F P+ +L+G + F
Sbjct: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAF 832
Query: 1458 CFGVNNQCH 1466
C V QCH
Sbjct: 833 CNPVTGQCH 841
Score = 58.2 bits (139), Expect = 1e-07
Identities = 54/191 (28%), Positives = 77/191 (40%), Gaps = 49/191 (25%)
Query: 1672 YYRDHKGLYTGRCVPCNCNGHSNQCQ--DG---------SGICVNCQHNTAGEHCERCQE 1720
YY + + G C C GH+++C DG G C+ C+HNT G +CE C +
Sbjct: 259 YYAVYDMVVRGNCF---CYGHASECAPVDGFNEEVEGMVHGHCM-CRHNTKGLNCELCMD 314
Query: 1721 GYYG-------NAVHGSCRACPC-PHTNS--------FATGCVVNGGDVRCSCKAGYTGT 1764
Y+ +C+ C C H+ S ATG V G V C+ G
Sbjct: 315 FYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNV--SGGVCDDCQHNTMGR 372
Query: 1765 QCERCAPGYFGNPQ---KFGGSCQPCSCNSNGQL--GSCHPLT--------GDCINQEPK 1811
CE+C P Y+ +P+ + C+ C+C+ G G C T G C K
Sbjct: 373 NCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQC---RCK 429
Query: 1812 DSSPAEECDDC 1822
+ E CD C
Sbjct: 430 LNVEGEHCDVC 440
Score = 51.2 bits (121), Expect = 2e-05
Identities = 20/43 (46%), Positives = 25/43 (58%)
Query: 1262 GALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHY 1304
G PC+C GA C E GQC C+P++IGRQC G+Y
Sbjct: 506 GCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYY 548
Score = 40.8 bits (94), Expect = 0.023
Identities = 64/343 (18%), Positives = 143/343 (41%), Gaps = 49/343 (14%)
Query: 1821 DCDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAG--LLEQ---MRHMETQAKDLRNQLL 1875
D D V++ L ++ + + + K + SA LL+ M+ ++LRN +
Sbjct: 1446 DLDQDVLSALAEVEQLSKMVSEAKLRADEAKQSAEDILLKTNATKEKMDKSNEELRNLIK 1505
Query: 1876 NYRSAISNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKELDV 1935
R+ ++ + ++ +E E L+ + ++ Q L ++ +S +++V
Sbjct: 1506 QIRNFLTQDSADLDSIEAVAN------EVLKMEMPSTPQQLQNLTEDIRERVESLSQVEV 1559
Query: 1936 KIKNV---IRNVHILLKQISGTDGEGNNVP-SGDFSREWAEAQRMMRELRNRNFGKHLRE 1991
+++ I +LL++ +V + D +E E + K +++
Sbjct: 1560 ILQHSAADIARAEMLLEEAKRASKSATDVKVTADMVKEALEEAEKAQVAAE----KAIKQ 1615
Query: 1992 AEADKRESQLLLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQA-- 2049
A+ D + +Q LL I + +T E S R ++E E + +L+ + + + +A
Sbjct: 1616 ADEDIQGTQNLLTSIES--ETAASEETLFNASQR--ISELERNVEELKRKAAQNSGEAEY 1671
Query: 2050 ----------------KQANG-LNQENERALGAIQRQVKEINSLQSDFTKYLTTADSSLL 2092
K +G L+++ ++ I ++ +E + A + L
Sbjct: 1672 IEKVVYTVKQSAEDVKKTLDGELDEKYKKVENLIAKKTEESADARRKAEMLQNEAKTLLA 1731
Query: 2093 QTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGK 2135
Q N LQL++ +++YE + ++ L DK +EL+R G+
Sbjct: 1732 QANSKLQLLKDLERKYE-------DNQRYLEDKAQELARLEGE 1767
Score = 33.9 bits (76), Expect = 2.8
Identities = 20/71 (28%), Positives = 27/71 (38%), Gaps = 9/71 (12%)
Query: 1401 ECVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCREGSFHL-----DPANLKGCTS 1455
EC P DG V G C+C+ N +G C +C + L + N C
Sbjct: 279 ECAPV----DGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKK 334
Query: 1456 CFCFGVNNQCH 1466
C C + CH
Sbjct: 335 CNCNEHSISCH 345
>gi|148613884 netrin 1 [Homo sapiens]
Length = 604
Score = 256 bits (653), Expect = 3e-67
Identities = 150/451 (33%), Positives = 236/451 (52%), Gaps = 50/451 (11%)
Query: 49 PTYFNLAEAARIWATATCGERGPGEGRPQPELYCKLVGGPTAPGSGHTIQGQFCDYCNSE 108
P + N A + ++TCG RP P YC + + G + C CN+
Sbjct: 53 PDFVNAAFGKDVRVSSTCG-------RP-PARYCVV----SERGEERL---RSCHLCNAS 97
Query: 109 DPRKAHPVTNAIDGSE----RWWQSPPLSSGTQY-NRVNLTLDLGQLFHVAYILIKFANS 163
DP+KAHP D + WQS + Q+ + V LTL LG+ F V Y+ ++F S
Sbjct: 98 DPKKAHPPAFLTDLNNPHNLTCWQS---ENYLQFPHNVTLTLSLGKKFEVTYVSLQFC-S 153
Query: 164 PRPDLWVLERSVDFGSTYSPWQYFAHSKVDCLKEFGREANMAVTR--DDDVLCVTEYSRI 221
PRP+ + +S+D+G T+ P+Q+++ C K + R +T+ + + +C ++ +
Sbjct: 154 PRPESMAIYKSMDYGRTWVPFQFYS---TQCRKMYNRPHRAPITKQNEQEAVCTDSHTDM 210
Query: 222 VPLENGEVVVSLINGRPGAKNFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDPT 281
PL G + S ++GRP A +F S L+++ AT+IR+ F R +T + + D
Sbjct: 211 RPLSGGLIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVAFSRLHTFG----DENEDDSE 266
Query: 282 VTR-RYYYSIKDISIGGQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQR 340
+ R Y+Y++ D+ +GG+C CNGHA C + + L C+C+H+T G CDRC + R
Sbjct: 267 LARDSYFYAVSDLQVGGRCKCNGHAARCVRDRDDSLV-CDCRHNTAGPECDRCKPFHYDR 325
Query: 341 RWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGV 400
W+ A +++EC ACNC+ HA C ++ ++ + + GGVC+NC+HNTAG
Sbjct: 326 PWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKS-------GGVCLNCRHNTAGR 378
Query: 401 NCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADG--CEQGSGRCHCKPNFHGDNCEKCA 458
+C C +GYYR G P+ C C C P A G C Q +G+C CK G C +CA
Sbjct: 379 HCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCA 438
Query: 459 IGYYN----FPFCLRIPIFPVSTPSS--EDP 483
GY C++IP+ P +T +S E+P
Sbjct: 439 KGYQQSRSPIAPCIKIPVAPPTTAASSVEEP 469
Score = 104 bits (259), Expect = 2e-21
Identities = 66/192 (34%), Positives = 84/192 (43%), Gaps = 40/192 (20%)
Query: 1653 ICACPPAYAGDSCQGCSPGYYRDHKGLYTGR----CVPCNCNGHSNQCQ----------- 1697
+C C AG C C P +Y T R CV CNCN H+ +C+
Sbjct: 303 VCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGR 362
Query: 1698 DGSGICVNCQHNTAGEHCERCQEGYY---GNAV--HGSCRACPCPHTNSFATGCVVNGGD 1752
G+C+NC+HNTAG HC C+EGYY G + +C+AC C A G N
Sbjct: 363 KSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVG--AAGKTCNQTT 420
Query: 1753 VRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKD 1812
+C CK G TG C RCA GY Q+ PC ++ P T
Sbjct: 421 GQCPCKDGVTGITCNRCAKGY----QQSRSPIAPCI-----KIPVAPPTTA--------- 462
Query: 1813 SSPAEECDDCDS 1824
+S EE +DCDS
Sbjct: 463 ASSVEEPEDCDS 474
Score = 75.9 bits (185), Expect = 6e-13
Identities = 50/160 (31%), Positives = 68/160 (42%), Gaps = 31/160 (19%)
Query: 1687 CNCNGHSNQC---QDGSGICVNCQHNTAGEHCERCQEGYYGNAVH-------GSCRACPC 1736
C CNGH+ +C +D S +C +C+HNTAG C+RC+ +Y C AC C
Sbjct: 285 CKCNGHAARCVRDRDDSLVC-DCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNC 343
Query: 1737 PHTNSFATGCVVN----------GGDVRCSCKAGYTGTQCERCAPGYF---GNPQKFGGS 1783
N A C N G V +C+ G C C GY+ G P +
Sbjct: 344 ---NLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKA 400
Query: 1784 CQPCSCNSNGQLG-SCHPLTGDCINQEPKDSSPAEECDDC 1822
C+ C C+ G G +C+ TG C KD C+ C
Sbjct: 401 CKACDCHPVGAAGKTCNQTTGQC---PCKDGVTGITCNRC 437
Score = 74.3 bits (181), Expect = 2e-12
Identities = 52/168 (30%), Positives = 71/168 (42%), Gaps = 33/168 (19%)
Query: 426 CSCDPEHADGC---EQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSED 482
C C+ HA C S C C+ N G C++C +Y+ P+ +
Sbjct: 285 CKCNG-HAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPW-----------QRATA 332
Query: 483 PVAGDIKGCDCNLEG----VLPEICDAHGR-----CL-CRPGVEGPRCDTCRSGFY---S 529
A + C+CNL E+ GR CL CR G C C+ G+Y
Sbjct: 333 REANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMG 392
Query: 530 FPI-----CQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSG 572
PI C+AC C +G+ C+ TGQC C+ GVTG C+RC G
Sbjct: 393 KPITHRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKG 440
Score = 65.9 bits (159), Expect = 7e-10
Identities = 41/141 (29%), Positives = 53/141 (37%), Gaps = 28/141 (19%)
Query: 555 CECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQCKLHVE-------- 606
C+CR G CDRC YD P + ++ + N NL +C+ ++E
Sbjct: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRK 363
Query: 607 -------------GPTCSRCKLLYWNLDKENP----SGCSECKCHKAGTVSGTGECRQGD 649
G C CK Y+ D P C C CH G T C Q
Sbjct: 364 SGGVCLNCRHNTAGRHCHYCKEGYYR-DMGKPITHRKACKACDCHPVGAAGKT--CNQTT 420
Query: 650 GDCHCKSHVGGDSCDTCEDGY 670
G C CK V G +C+ C GY
Sbjct: 421 GQCPCKDGVTGITCNRCAKGY 441
Score = 64.3 bits (155), Expect = 2e-09
Identities = 38/137 (27%), Positives = 53/137 (38%), Gaps = 21/137 (15%)
Query: 1326 CRCPPRTVRPQCEVCETHSF-------SFHPMAGCEGCNCSR-----RGTIEAAMPECDR 1373
C C T P+C+ C+ + + C CNC+ R +E +
Sbjct: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRK 363
Query: 1374 DSGQC-RCKPRITGRQCDRCASGFYRF--------PECVPCNCNRDGTEPGVCDPGTGAC 1424
G C C+ GR C C G+YR C C+C+ G C+ TG C
Sbjct: 364 SGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQC 423
Query: 1425 LCKENVEGTECNVCREG 1441
CK+ V G CN C +G
Sbjct: 424 PCKDGVTGITCNRCAKG 440
Score = 63.9 bits (154), Expect = 2e-09
Identities = 51/193 (26%), Positives = 69/193 (35%), Gaps = 44/193 (22%)
Query: 1266 CECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFP----------RCKPCSCG 1315
C+C+ A + C C+ N G +C RC HY P C C+C
Sbjct: 285 CKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCN 344
Query: 1316 --RRLCE-----------EMTGQC-RCPPRTVRPQCEVCETHSFS------FHPMAGCEG 1355
R C + G C C T C C+ + H A C+
Sbjct: 345 LHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKA-CKA 403
Query: 1356 CNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGF----------YRFPECVPC 1405
C+C G AA C++ +GQC CK +TG C+RCA G+ + P P
Sbjct: 404 CDCHPVG---AAGKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAPPT 460
Query: 1406 NCNRDGTEPGVCD 1418
EP CD
Sbjct: 461 TAASSVEEPEDCD 473
Score = 57.0 bits (136), Expect = 3e-07
Identities = 33/93 (35%), Positives = 39/93 (41%), Gaps = 13/93 (13%)
Query: 1217 LHKKSMDKSLEFITNCGKNSFYLDPQTASRFCKNSARSLVA------FYHKGALPCECHP 1270
L+K S KS NC N TA R C + K C+CHP
Sbjct: 356 LYKLSGRKSGGVCLNCRHN-------TAGRHCHYCKEGYYRDMGKPITHRKACKACDCHP 408
Query: 1271 TGATGPHCSPEGGQCPCQPNVIGRQCTRCATGH 1303
GA G C+ GQCPC+ V G C RCA G+
Sbjct: 409 VGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGY 441
Score = 51.2 bits (121), Expect = 2e-05
Identities = 39/135 (28%), Positives = 50/135 (37%), Gaps = 35/135 (25%)
Query: 1355 GCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFP----------ECVP 1404
G C G + + D DS C C+ G +CDRC Y P ECV
Sbjct: 282 GGRCKCNGHAARCVRDRD-DSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVA 340
Query: 1405 CNCNR--------------DGTEPGVCDPGTGACL-CKENVEGTECNVCREGSFH---LD 1446
CNCN G + G G CL C+ N G C+ C+EG +
Sbjct: 341 CNCNLHARRCRFNMELYKLSGRKSG------GVCLNCRHNTAGRHCHYCKEGYYRDMGKP 394
Query: 1447 PANLKGCTSCFCFGV 1461
+ K C +C C V
Sbjct: 395 ITHRKACKACDCHPV 409
>gi|119703755 laminin, beta 2 precursor [Homo sapiens]
Length = 1798
Score = 252 bits (644), Expect = 4e-66
Identities = 185/615 (30%), Positives = 270/615 (43%), Gaps = 96/615 (15%)
Query: 1 MAAAARPRGRALGPVLPPTPLLLLVLRVLPACGATARDP---GAAAGLSLHPTYFNL--A 55
M +R RGR G LP L L+L VL A A A P G + G S +P +L
Sbjct: 1 MELTSRERGR--GQPLPWELRLGLLLSVLAATLAQAPAPDVPGCSRG-SCYPATGDLLVG 57
Query: 56 EAARIWATATCGERGPGEGRPQPELYCKLVGGPTAPGSGHTIQGQFCDYCNSEDPRKA-- 113
A R+ A++TCG GP QP YC + H + C C+S P A
Sbjct: 58 RADRLTASSTCGLNGP-----QP--YCIV---------SHLQDEKKCFLCDSRRPFSARD 101
Query: 114 ----HPVTNAIDG-----SERWWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKFANSP 164
H + N + WWQS V + LDL FH ++++ F
Sbjct: 102 NPHSHRIQNVVTSFAPQRRAAWWQSE-----NGIPAVTIQLDLEAEFHFTHLIMTFKTF- 155
Query: 165 RPDLWVLERSVDFGSTYSPWQYFAHSKVDCLKEFGREANMAVTRDDDVLCVTEYSRIVPL 224
RP ++ERS DFG T+ ++YF++ DC +F DDV+C + YS I P
Sbjct: 156 RPAAMLVERSADFGRTWHVYRYFSY---DCGADFPGVPLAPPRHWDDVVCESRYSEIEPS 212
Query: 225 ENGEVVVSLINGRPGAKNFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDPTVTR 284
GEV+ +++ + +S ++ K TN+R+ R +TL +L+ + +
Sbjct: 213 TEGEVIYRVLDPAIPIPD-PYSSRIQNLLKITNLRVNLTRLHTLGDNLLDPRRE---IRE 268
Query: 285 RYYYSIKDISIGGQCVCNGHAEVCNIN-----NPEKLFR--CECQHHTCGETCDRCCTGY 337
+YYY++ ++ + G C C GHA C + E + C C+H+T G C++C Y
Sbjct: 269 KYYYALYELVVRGNCFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFY 328
Query: 338 NQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNT 397
WRPA SH C C CHGH +C++D V +++ GGVC CQHNT
Sbjct: 329 RDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASGNVS-------GGVCDGCQHNT 381
Query: 398 AGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDP---EHADGCEQG--------SGRCHCK 446
AG +CE C +YR + P C C CDP + C+ SG+C CK
Sbjct: 382 AGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCK 441
Query: 447 PNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLP--EICD 504
+ G C++C G++ R+ + C CN G +P CD
Sbjct: 442 EHVVGTRCQQCRDGFFGLSISDRL----------------GCRRCQCNARGTVPGSTPCD 485
Query: 505 AH-GRCLCRPGVEGPRCDTCRSGFYSFPI----CQACWCSALGSYQMPCSSVTGQCECRP 559
+ G C C+ V G CD C G + C+ C C G+ C TGQC CR
Sbjct: 486 PNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQ 545
Query: 560 GVTGQRCDRCLSGAY 574
+ G+RC++ G +
Sbjct: 546 HMVGRRCEQVQPGYF 560
Score = 167 bits (424), Expect = 1e-40
Identities = 120/403 (29%), Positives = 162/403 (40%), Gaps = 87/403 (21%)
Query: 318 RCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQAS 377
+C C+ G CDRC G +W + C C C+GHA C
Sbjct: 849 QCLCRTGAFGLRCDRCQRG----QWGFPS------CRPCVCNGHADEC------------ 886
Query: 378 LNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPE------ 431
NT G C+ C+ +T G +CE+C G++ +P C PC C PE
Sbjct: 887 -NTHT-----GACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQ--CRPCPC-PEGPGSQR 937
Query: 432 -HADGCEQGSGR----CHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAG 486
A C Q CHC+ + G CE CA G++ P S P G
Sbjct: 938 HFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDP----------SRPG------G 981
Query: 487 DIKGCDC--NLEGVLPEICDAH-GRCL-CRPGVEGPRCDTCRSGFYSFPI---CQACWCS 539
+ C+C N++ + P+ CD H G+CL C EGP C C+ GF+ C C C+
Sbjct: 982 RCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCTCN 1041
Query: 540 ALGSYQMPCSSV--------TGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSS-ACDPAG 590
LG+ C S +GQC C P V G CDRC ++ G AC P+
Sbjct: 1042 LLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQPCACHPSR 1101
Query: 591 ----TINSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECR 646
T N G C C+ G TCS C+ L+W + C C C G T +C
Sbjct: 1102 ARGPTCNEFTGQCHCRAGFGGRTCSECQELHWG---DPGLQCHACDCDSRGI--DTPQCH 1156
Query: 647 QGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIG 689
+ G C C+ V G CD C G+ + + C C G
Sbjct: 1157 RFTGHCSCRPGVSGVRCDQCARGFSGI----FPACHPCHACFG 1195
Score = 164 bits (415), Expect = 1e-39
Identities = 102/336 (30%), Positives = 145/336 (43%), Gaps = 77/336 (22%)
Query: 423 CIPCSCDPEHADGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSED 482
C P P HA+G G+ C CK N G NCE+C Y + P+ +ED
Sbjct: 292 CAPAPGAPAHAEGMVHGA--CICKHNTRGLNCEQCQDFYRDLPW-----------RPAED 338
Query: 483 PVAGDIKGCDCNLE---------------GVLPEICDAHGRCLCRPGVEGPRCDTCRSGF 527
+ + C+C+ V +CD C+ G C+ CR F
Sbjct: 339 GHSHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDG-----CQHNTAGRHCELCRPFF 393
Query: 528 YSFP--------ICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHC 579
Y P +C++C C +GS G RCD
Sbjct: 394 YRDPTKDLRDPAVCRSCDCDPMGSQD-----------------GGRCD------------ 424
Query: 580 QGSSSACDPAGTINSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTV 639
S DPA + S G C+CK HV G C +C+ ++ L + GC C+C+ GTV
Sbjct: 425 ----SHDDPALGLVS--GQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTV 478
Query: 640 SGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGP 699
G+ C G C+CK V G CD C G++ L + GC+ C CD+GGAL C
Sbjct: 479 PGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGL-SHDLLGCRPCDCDVGGALDPQCDEG 537
Query: 700 SGVCQCREHVVGKVCQRPENNYYFPDLHHMKYEIED 735
+G C CR+H+VG+ C++ + Y+ P L H+ +E ED
Sbjct: 538 TGQCHCRQHMVGRRCEQVQPGYFRPFLDHLIWEAED 573
Score = 150 bits (380), Expect = 2e-35
Identities = 119/412 (28%), Positives = 153/412 (37%), Gaps = 93/412 (22%)
Query: 387 GGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADG--CEQGSGRCH 444
GG C+ C+ G C+ CA GYY +G P GC C C E A CE+ SG+C
Sbjct: 799 GGQCL-CKPGVVGRRCDLCAPGYYG-FG-----PTGCQACQCSHEGALSSLCEKTSGQCL 851
Query: 445 CKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICD 504
C+ G C++C G + FP C P + G GC + G E C
Sbjct: 852 CRTGAFGLRCDRCQRGQWGFPSCR--PCVCNGHADECNTHTGACLGCRDHTGGEHCERCI 909
Query: 505 A--HGR--------------------------------------CLCRPGVEGPRCDTCR 524
A HG C CR G G RC+ C
Sbjct: 910 AGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACA 969
Query: 525 SGFYSFPI-----CQACWCSALGSYQMP--CSSVTGQC-------------ECRPGVTG- 563
G + P CQ C CS P C TGQC C+PG G
Sbjct: 970 PGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQ 1029
Query: 564 ---QRCDRC---LSGAYDFPHCQGSSSACDPAGTINSNLGYCQCKLHVEGPTCSRCKLLY 617
Q C RC L G CDP+ G C C +V+GP+C RC +
Sbjct: 1030 AARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSS------GQCPCLPNVQGPSCDRCAPNF 1083
Query: 618 WNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSN 677
WNL + GC C CH + T C + G CHC++ GG +C C++ ++
Sbjct: 1084 WNLTSGH--GCQPCACHPSRARGPT--CNEFTGQCHCRAGFGGRTCSECQELHWG---DP 1136
Query: 678 YFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENNY--YFPDLH 727
C C CD G + C +G C CR V G C + + FP H
Sbjct: 1137 GLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFPACH 1188
Score = 147 bits (370), Expect = 2e-34
Identities = 101/343 (29%), Positives = 138/343 (40%), Gaps = 71/343 (20%)
Query: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 358
CVCNGHA+ CN + L C+ HT GE C+RC G++ P +C C C
Sbjct: 877 CVCNGHADECNTHTGACL---GCRDHTGGEHCERCIAGFHGDPRLP----YGGQCRPCPC 929
Query: 359 HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVD 418
P +R A+ Q Y+ VC +C+ G+ CE CA G++ G P
Sbjct: 930 PE-------GPGSQRHFATSCHQDEYSQQIVC-HCRAGYTGLRCEACAPGHF---GDPSR 978
Query: 419 APDGCIPCSC----DPEHADGCEQGSGRC-------------HCKPNFHGD----NCEKC 457
C C C DP D C+ +G+C HCKP FHG +C +C
Sbjct: 979 PGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRC 1038
Query: 458 AIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEG 517
C + P PS + C C+ + G+C C P V+G
Sbjct: 1039 T--------CNLLGTNPQQCPSPDQ--------CHCD---------PSSGQCPCLPNVQG 1073
Query: 518 PRCDTCRSGFYSFPI---CQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAY 574
P CD C F++ CQ C C + C+ TGQC CR G G+ C C +
Sbjct: 1074 PSCDRCAPNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHW 1133
Query: 575 DFPHCQGSSSACDPAG----TINSNLGYCQCKLHVEGPTCSRC 613
P Q + CD G + G+C C+ V G C +C
Sbjct: 1134 GDPGLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQC 1176
Score = 141 bits (356), Expect = 9e-33
Identities = 95/332 (28%), Positives = 134/332 (40%), Gaps = 55/332 (16%)
Query: 421 DGCIPCSCDPEHA--DGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTP 478
+G +PC C+P+ + C G+C CKP G C+ CA GYY F P
Sbjct: 778 NGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGF------------GP 825
Query: 479 SSEDPVAGDIKGCDCNLEGVLPEICD-AHGRCLCRPGVEGPRCDTCRSGFYSFPICQACW 537
+ + C C+ EG L +C+ G+CLCR G G RCD C+ G + FP C+ C
Sbjct: 826 TG-------CQACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCV 878
Query: 538 CSALGSYQMPCSSVTGQC-ECRPGVTGQRCDRCLSGAYDFPHCQ--GSSSACD-PAGTIN 593
C+ + C++ TG C CR G+ C+RC++G + P G C P G +
Sbjct: 879 CN---GHADECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGS 935
Query: 594 -------------SNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSG-CSECKCHKAGTV 639
S C C+ G C C ++ D P G C C+C
Sbjct: 936 QRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFG-DPSRPGGRCQLCECSGNIDP 994
Query: 640 SGTGECRQGDGDC-HCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSG 698
C G C C H G C C+ G+ ++ C C C++ G C
Sbjct: 995 MDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHG--QAARQSCHRCTCNLLGTNPQQCPS 1052
Query: 699 P--------SGVCQCREHVVGKVCQRPENNYY 722
P SG C C +V G C R N++
Sbjct: 1053 PDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFW 1084
Score = 140 bits (353), Expect = 2e-32
Identities = 73/207 (35%), Positives = 98/207 (47%), Gaps = 54/207 (26%)
Query: 1654 CACPPAYAGDSCQGCSPGYYR-----------DHKGLYT-------GRCV---------- 1685
C C P G C C+PGYY H+G + G+C+
Sbjct: 802 CLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEGALSSLCEKTSGQCLCRTGAFGLRC 861
Query: 1686 --------------PCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNA---VH 1728
PC CNGH+++C +G C+ C+ +T GEHCERC G++G+
Sbjct: 862 DRCQRGQWGFPSCRPCVCNGHADECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYG 921
Query: 1729 GSCRACPCPH----TNSFATGCVVN--GGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGG 1782
G CR CPCP FAT C + + C C+AGYTG +CE CAPG+FG+P + GG
Sbjct: 922 GQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGG 981
Query: 1783 SCQPCSCNSN---GQLGSCHPLTGDCI 1806
CQ C C+ N +C P TG C+
Sbjct: 982 RCQLCECSGNIDPMDPDACDPHTGQCL 1008
Score = 133 bits (334), Expect = 3e-30
Identities = 78/258 (30%), Positives = 110/258 (42%), Gaps = 45/258 (17%)
Query: 1232 CGKNSFYLDPQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNV 1291
C + + S C SL + GALPC+C+P G+ C+P GGQC C+P V
Sbjct: 749 CHEEGLVPSKTSPSEACAPLLISLSTLIYNGALPCQCNPQGSLSSECNPHGGQCLCKPGV 808
Query: 1292 IGRQCTRCATGHYGF--PRCKPCSCGRR-----LCEEMTGQCRCPPRTVRPQCEVCETHS 1344
+GR+C CA G+YGF C+ C C LCE+ +GQC C +C+ C+
Sbjct: 809 VGRRCDLCAPGYYGFGPTGCQACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQ 868
Query: 1345 FSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQC-RCKPRITGRQCDRCASGFYRFP--- 1400
+ F C C C+ EC+ +G C C+ G C+RC +GF+ P
Sbjct: 869 WGF---PSCRPCVCNGHA------DECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLP 919
Query: 1401 ---ECVPC--------------NCNRDGTEPGVCDPGTGACLCKENVEGTECNVCREGSF 1443
+C PC +C++D + C C+ G C C G F
Sbjct: 920 YGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQI------VCHCRAGYTGLRCEACAPGHF 973
Query: 1444 HLDPANLKG-CTSCFCFG 1460
DP+ G C C C G
Sbjct: 974 G-DPSRPGGRCQLCECSG 990
Score = 115 bits (288), Expect = 7e-25
Identities = 67/193 (34%), Positives = 86/193 (44%), Gaps = 34/193 (17%)
Query: 1282 GGQCP-CQPNVIGRQCTRCATGHYGFPR--------CKPCSC--------GRRLCEE--- 1321
GG C CQ N GR C C Y P C+ C C GR C+
Sbjct: 371 GGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGR--CDSHDD 428
Query: 1322 -----MTGQCRCPPRTVRPQCEVCETHSF--SFHPMAGCEGCNCSRRGTIEAAMPECDRD 1374
++GQCRC V +C+ C F S GC C C+ RGT+ + P CD +
Sbjct: 429 PALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTP-CDPN 487
Query: 1375 SGQCRCKPRITGRQCDRCASGFYRFPE----CVPCNCNRDGTEPGVCDPGTGACLCKENV 1430
SG C CK +TGR CDRC G + C PC+C+ G CD GTG C C++++
Sbjct: 488 SGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHM 547
Query: 1431 EGTECNVCREGSF 1443
G C + G F
Sbjct: 548 VGRRCEQVQPGYF 560
Score = 110 bits (276), Expect = 2e-23
Identities = 55/181 (30%), Positives = 81/181 (44%), Gaps = 15/181 (8%)
Query: 1653 ICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGH-----SNQCQDGSGICVNCQ 1707
+C C Y G C+ C+PG++ D GRC C C+G+ + C +G C+ C
Sbjct: 953 VCHCRAGYTGLRCEACAPGHFGD-PSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCL 1011
Query: 1708 HNTAGEHCERCQEGYYGNAVHGSCRACPC------PHTNSFATGCVVNGGDVRCSCKAGY 1761
H+T G HC C+ G++G A SC C C P C + +C C
Sbjct: 1012 HHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNV 1071
Query: 1762 TGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLG-SCHPLTGDCINQEPKDSSPAEECD 1820
G C+RCAP ++ G CQPC+C+ + G +C+ TG C + EC
Sbjct: 1072 QGPSCDRCAPNFWNLTS--GHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQ 1129
Query: 1821 D 1821
+
Sbjct: 1130 E 1130
Score = 109 bits (272), Expect = 5e-23
Identities = 54/139 (38%), Positives = 68/139 (48%), Gaps = 13/139 (9%)
Query: 1277 HCSPEGGQCPCQPNVIGRQCTRCATGHYGFPR---CKPCSCGRR-----LCEEMTGQCRC 1328
HC P GQCPC PNV G C RCA + C+PC+C C E TGQC C
Sbjct: 1057 HCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHC 1116
Query: 1329 PPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQ 1388
C C+ + P C C+C RG P+C R +G C C+P ++G +
Sbjct: 1117 RAGFGGRTCSECQELHWG-DPGLQCHACDCDSRG---IDTPQCHRFTGHCSCRPGVSGVR 1172
Query: 1389 CDRCASGFYR-FPECVPCN 1406
CD+CA GF FP C PC+
Sbjct: 1173 CDQCARGFSGIFPACHPCH 1191
Score = 102 bits (253), Expect = 8e-21
Identities = 65/219 (29%), Positives = 88/219 (40%), Gaps = 33/219 (15%)
Query: 1266 CECHPTGATGPH----CSPEGGQC-PCQPNVIGRQCTRCATGHYGFPR---CKPCSCG-- 1315
CEC +G P C P GQC C + G C C G +G C C+C
Sbjct: 986 CEC--SGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCTCNLL 1043
Query: 1316 -----------RRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTI 1364
+ C+ +GQC C P P C+ C + ++ GC+ C C
Sbjct: 1044 GTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQPCACHPS--- 1100
Query: 1365 EAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFP--ECVPCNCNRDGTEPGVCDPGTG 1422
A P C+ +GQC C+ GR C C + P +C C+C+ G + C TG
Sbjct: 1101 RARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCHACDCDSRGIDTPQCHRFTG 1160
Query: 1423 ACLCKENVEGTECNVCREGSFHLDPANLKGCTSCF-CFG 1460
C C+ V G C+ C G + PA C C CFG
Sbjct: 1161 HCSCRPGVSGVRCDQCARGFSGIFPA----CHPCHACFG 1195
Score = 95.5 bits (236), Expect = 8e-19
Identities = 71/237 (29%), Positives = 91/237 (38%), Gaps = 48/237 (20%)
Query: 1267 ECHPTGATGPHCSPEG---GQCPCQPNVIGRQCTRCATGHYGFP----------RCKPCS 1313
EC P A G EG G C C+ N G C +C + P C+ C
Sbjct: 291 ECAP--APGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCE 348
Query: 1314 CGRRL--CE-EMT----------GQCR-CPPRTVRPQCEVCETHSF-----SFHPMAGCE 1354
C C +M G C C T CE+C + A C
Sbjct: 349 CHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCR 408
Query: 1355 GCNCSRRGTIEAAMPECDRD------SGQCRCKPRITGRQCDRCASGFYRFP-----ECV 1403
C+C G+ + + D SGQCRCK + G +C +C GF+ C
Sbjct: 409 SCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCR 468
Query: 1404 PCNCNRDGTEPGV--CDPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFC 1458
C CN GT PG CDP +G+C CK V G C+ C G + L +L GC C C
Sbjct: 469 RCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLS-HDLLGCRPCDC 524
Score = 94.7 bits (234), Expect = 1e-18
Identities = 53/160 (33%), Positives = 77/160 (48%), Gaps = 17/160 (10%)
Query: 1666 QGCSPGYYRDHKGLYTGRCVPCNCNGH---SNQCQDGSGICVNCQHNTAGEHCERCQEGY 1722
+ C+P +Y G +PC CN S++C G C+ C+ G C+ C GY
Sbjct: 763 EACAPLLISLSTLIYNG-ALPCQCNPQGSLSSECNPHGGQCL-CKPGVVGRRCDLCAPGY 820
Query: 1723 YGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGG 1782
YG G C+AC C H + ++ C G +C C+ G G +C+RC G +G P
Sbjct: 821 YGFGPTG-CQACQCSHEGALSSLCEKTSG--QCLCRTGAFGLRCDRCQRGQWGFP----- 872
Query: 1783 SCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 1822
SC+PC C NG C+ TG C+ +D + E C+ C
Sbjct: 873 SCRPCVC--NGHADECNTHTGACLG--CRDHTGGEHCERC 908
Score = 93.2 bits (230), Expect = 4e-18
Identities = 55/182 (30%), Positives = 79/182 (43%), Gaps = 30/182 (16%)
Query: 1654 CACPPAYAGDSCQGCSPGY----YRDHKGLYTGRCVPCNCNGHSNQCQD----------- 1698
C C G +C+ C Y +R + ++ C C C+GH++ C
Sbjct: 310 CICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASGNV 369
Query: 1699 GSGICVNCQHNTAGEHCERCQEGYYGNAVH-----GSCRACPCPHTNSFATGCVVNGGDV 1753
G+C CQHNTAG HCE C+ +Y + CR+C C S G + D
Sbjct: 370 SGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDP 429
Query: 1754 -------RCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQL-GS--CHPLTG 1803
+C CK GT+C++C G+FG C+ C CN+ G + GS C P +G
Sbjct: 430 ALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSG 489
Query: 1804 DC 1805
C
Sbjct: 490 SC 491
Score = 88.6 bits (218), Expect = 9e-17
Identities = 45/155 (29%), Positives = 70/155 (45%), Gaps = 25/155 (16%)
Query: 1266 CECHPTGAT-GPHCSPE--------GGQCPCQPNVIGRQCTRCATGHYGFP-----RCKP 1311
C+C P G+ G C GQC C+ +V+G +C +C G +G C+
Sbjct: 410 CDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRR 469
Query: 1312 CSCGRR-------LCEEMTGQCRCPPRTVRPQCEVC-ETHSFSFHPMAGCEGCNCSRRGT 1363
C C R C+ +G C C C+ C H H + GC C+C G
Sbjct: 470 CQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGA 529
Query: 1364 IEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYR 1398
++ P+CD +GQC C+ + GR+C++ G++R
Sbjct: 530 LD---PQCDEGTGQCHCRQHMVGRRCEQVQPGYFR 561
Score = 81.6 bits (200), Expect = 1e-14
Identities = 53/169 (31%), Positives = 74/169 (43%), Gaps = 23/169 (13%)
Query: 1656 CPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDG--------------SG 1701
C AG C+ C P +YRD V +C+ QDG SG
Sbjct: 377 CQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSG 436
Query: 1702 ICVNCQHNTAGEHCERCQEGYYGNAVHG--SCRACPCPHTNSF--ATGCVVNGGDVRCSC 1757
C C+ + G C++C++G++G ++ CR C C + +T C N G C C
Sbjct: 437 QC-RCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGS--CYC 493
Query: 1758 KAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLG-SCHPLTGDC 1805
K TG C+RC PG++G G C+PC C+ G L C TG C
Sbjct: 494 KRLVTGRGCDRCLPGHWGLSHDLLG-CRPCDCDVGGALDPQCDEGTGQC 541
Score = 77.4 bits (189), Expect = 2e-13
Identities = 49/132 (37%), Positives = 61/132 (46%), Gaps = 14/132 (10%)
Query: 600 QCKLHVEGPTCSR------CKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCH 653
QC H EG S+ C L +L +G C+C+ G++S EC G C
Sbjct: 748 QC--HEEGLVPSKTSPSEACAPLLISLSTLIYNGALPCQCNPQGSLSS--ECNPHGGQCL 803
Query: 654 CKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKV 713
CK V G CD C GY+ + GCQ CQC GALSS+C SG C CR G
Sbjct: 804 CKPGVVGRRCDLCAPGYYGFGPT---GCQACQCSHEGALSSLCEKTSGQCLCRTGAFGLR 860
Query: 714 CQRPENNYY-FP 724
C R + + FP
Sbjct: 861 CDRCQRGQWGFP 872
Score = 73.9 bits (180), Expect = 2e-12
Identities = 39/106 (36%), Positives = 47/106 (44%), Gaps = 13/106 (12%)
Query: 1262 GALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFP--RCKPCSCGRR-- 1317
G PC CHP+ A GP C+ GQC C+ GR C+ C H+G P +C C C R
Sbjct: 1091 GCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCHACDCDSRGI 1150
Query: 1318 ---LCEEMTGQCRCPPRTVRPQCEVCETHSFS-----FHPMAGCEG 1355
C TG C C P +C+ C FS HP C G
Sbjct: 1151 DTPQCHRFTGHCSCRPGVSGVRCDQC-ARGFSGIFPACHPCHACFG 1195
Score = 65.9 bits (159), Expect = 7e-10
Identities = 41/132 (31%), Positives = 54/132 (40%), Gaps = 20/132 (15%)
Query: 1654 CACPPAYAGDSCQGCSPGYY----RDHKGLYTGRCVPCNCNGH-----SNQCQDGSGICV 1704
C C G CQ C G++ D G C C CN S C SG C
Sbjct: 438 CRCKEHVVGTRCQQCRDGFFGLSISDRLG-----CRRCQCNARGTVPGSTPCDPNSGSCY 492
Query: 1705 NCQHNTAGEHCERCQEGYYGNAVHG--SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYT 1762
C+ G C+RC G++G + H CR C C + C + G +C C+
Sbjct: 493 -CKRLVTGRGCDRCLPGHWGLS-HDLLGCRPCDCDVGGALDPQC--DEGTGQCHCRQHMV 548
Query: 1763 GTQCERCAPGYF 1774
G +CE+ PGYF
Sbjct: 549 GRRCEQVQPGYF 560
Score = 61.2 bits (147), Expect = 2e-08
Identities = 53/190 (27%), Positives = 80/190 (42%), Gaps = 46/190 (24%)
Query: 1672 YYRDHKGLYTGRCVPCNCNGHSNQCQDG-----------SGICVNCQHNTAGEHCERCQE 1720
YY ++ + G C C GH+++C G C+ C+HNT G +CE+CQ+
Sbjct: 271 YYALYELVVRGNCF---CYGHASECAPAPGAPAHAEGMVHGACI-CKHNTRGLNCEQCQD 326
Query: 1721 GY----YGNAVHG---SCRACPC-PHTNS--------FATGCVVNGGDVRCSCKAGYTGT 1764
Y + A G +CR C C HT+S A+G V G V C+ G
Sbjct: 327 FYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASGNV--SGGVCDGCQHNTAGR 384
Query: 1765 QCERCAPGYFGNPQK---FGGSCQPCSCNSNGQL--GSCHP--------LTGDCINQEPK 1811
CE C P ++ +P K C+ C C+ G G C ++G C +E
Sbjct: 385 HCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHV 444
Query: 1812 DSSPAEECDD 1821
+ ++C D
Sbjct: 445 VGTRCQQCRD 454
Score = 47.0 bits (110), Expect = 3e-04
Identities = 34/124 (27%), Positives = 48/124 (38%), Gaps = 37/124 (29%)
Query: 298 QCVCNGHAEV-----CNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHE 352
+C CN V C+ N+ C C+ G CDRC G+ W SH+
Sbjct: 469 RCQCNARGTVPGSTPCDPNSGS----CYCKRLVTGRGCDRCLPGH---------WGLSHD 515
Query: 353 ---CEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGY 409
C C+C + DP + G G C +C+ + G CEQ GY
Sbjct: 516 LLGCRPCDCDVGGA---LDPQCDE------------GTGQC-HCRQHMVGRRCEQVQPGY 559
Query: 410 YRPY 413
+RP+
Sbjct: 560 FRPF 563
Score = 45.4 bits (106), Expect = 0.001
Identities = 16/43 (37%), Positives = 25/43 (58%)
Query: 1262 GALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHY 1304
G PC+C GA P C GQC C+ +++GR+C + G++
Sbjct: 518 GCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYF 560
Score = 38.1 bits (87), Expect = 0.15
Identities = 19/52 (36%), Positives = 25/52 (48%), Gaps = 9/52 (17%)
Query: 1422 GACLCKENVEGTECNVCREGSFHLD----PA---NLKGCTSCFCFGVNNQCH 1466
GAC+CK N G C C++ F+ D PA + C C C G + CH
Sbjct: 308 GACICKHNTRGLNCEQCQD--FYRDLPWRPAEDGHSHACRKCECHGHTHSCH 357
>gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens]
Length = 1193
Score = 243 bits (620), Expect = 2e-63
Identities = 292/1171 (24%), Positives = 481/1171 (41%), Gaps = 174/1171 (14%)
Query: 1328 CPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGR 1387
C T CE C+ + C CNC+ +G++ A CD +SG+C CKP +TG
Sbjct: 56 CNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSA---RCD-NSGRCSCKPGVTGA 111
Query: 1388 QCDRCASGFYRFPEC----------VPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNV 1437
+CDRC GF+ + C+C+ G G CD G C+CK V G C+
Sbjct: 112 RCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIA-GPCD--AGRCVCKPAVTGERCDR 168
Query: 1438 CREGSFHLDPANLKGCTSCFCFGVNNQCHSS-----HKRRTKF-VDMLGWHLETADRVDI 1491
CR G ++LD N +GCT CFC+G + C SS HK + F D+ GW +
Sbjct: 169 CRSGYYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSPA 228
Query: 1492 PVSFNPGSNSMVADLQELPATIHSASWVAPTSYLGDKVSSYGGYLTYQAKSFGLPGDMVL 1551
+ ++ + + Q L +VAP +LG++ SYG Q+ SF D
Sbjct: 229 KLQWSQRHQDVFSSAQRLDPVY----FVAPAKFLGNQQVSYG-----QSLSFDYRVDRGG 279
Query: 1552 LEKKP-DVQLTGQHMSIIYEETNTPRPDRLHHGRVHVVEGNFRHASSRAP-VSREELMTV 1609
DV L G + I + + + N +++ +P +S E +
Sbjct: 280 RHPSAHDVILEGAGLRITAPLMPLGKTLPCGLTKTYTFRLNEHPSNNWSPQLSYFEYRRL 339
Query: 1610 LSRLADVRIQGLYFTETQRLTLSEVGLEEASDTGSGRIALAVEICACPPAYAGDSCQGCS 1669
L L +RI+ Y E + V L A SG A VE C CP Y G CQ C+
Sbjct: 340 LRNLTALRIRATY-GEYSTGYIDNVTLISARPV-SGAPAPWVEQCICPVGYKGQFCQDCA 397
Query: 1670 PGYYRDHKGLYT-GRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVH 1728
GY RD L G C+PCNC G C +G C + N E C C G+Y N H
Sbjct: 398 SGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYSGDENPDIE-CADCPIGFY-NDPH 454
Query: 1729 G--SCRACPCPHTNSFATGCVVNGGDVRCS-CKAGYTGTQCERCAPGYFGNPQKFGG--- 1782
SC+ CPC N F+ + +V C+ C G TG +CE CA GYFG+P G
Sbjct: 455 DPRSCKPCPCH--NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVR 512
Query: 1783 SCQPCSCNSN---GQLGSCHPLTGDCIN------------------QEPKDSSPAEECDD 1821
CQPC CN+N G+C LTG C+ +P +PA++C
Sbjct: 513 PCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRA 572
Query: 1822 CDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAI 1881
C +C + + + K G + G Q K +Q + +
Sbjct: 573 C-NCNPMGSEPVGCRSDGTCVCKPGFGGPNCEHGAF-SCPACYNQVKIQMDQFMQQLQRM 630
Query: 1882 SNHGSKIEG---------LERELTDLNQEFETLQEKAQVNSRKAQTLN------------ 1920
SK +G LE + Q + + AQ++ +++L
Sbjct: 631 EALISKAQGGDGVVPDTELEGRMQQAEQALQDILRDAQISEGASRSLGLQLAKVRSQENS 690
Query: 1921 -----NNVNRATQSAKELDVKIKNVIRNVHILLKQISGTDGE-----GN-NVPSGD---- 1965
+++ + + L + +N +R+ H L+ Q+ + E GN N+P+ D
Sbjct: 691 YQSRLDDLKMTVERVRALGSQYQNRVRDTHRLITQMQLSLAESEASLGNTNIPASDHYVG 750
Query: 1966 ---FSREWAEAQRMMRE--LRNRNFGKHLREAEADKRESQLLLNRIRTWQKTHQGENNGL 2020
F EA R+ N + RE E +++ L+ + H+G +G
Sbjct: 751 PNGFKSLAQEATRLAESHVESASNMEQLTRETEDYSKQALSLVRK-----ALHEGVGSGS 805
Query: 2021 AN---SIRDSLNEYEAKLSDLRARLQEAAAQAK-QANGLNQENERALGAIQR-QVKEINS 2075
+ ++ L E K L +L A QA+ +A+ Q + R L ++ R Q S
Sbjct: 806 GSPDGAVVQGLVEKLEKTKSLAQQLTREATQAEIEADRSYQHSLRLLDSVSRLQGVSDQS 865
Query: 2076 LQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQ---------ELSDKV 2126
Q + K + SL +++ + M++ ++ + L EA+Q E SD++
Sbjct: 866 FQVEEAKRIKQKADSL--SSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQL 923
Query: 2127 ---RELSRSAGKTSL------VEEAEKHARSLQELAKQLEEIKRNASGDELVR------- 2170
L++S + +L E E ++L+E Q++ R A +E ++
Sbjct: 924 LSRANLAKSRAQEALSMGNATFYEVESILKNLREFDLQVD--NRKAEAEEAMKRLSYISQ 981
Query: 2171 CAVDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEA 2230
DA+ + A+ +A A RA + + AL+ I ++ ++ +L+ ++ + A
Sbjct: 982 KVSDASDKTQQAERALGSAAADAQRAKNGAGEALE--ISSEIEQEIGSLNLEANVTADGA 1039
Query: 2231 KMTQK---KLKQEVSPALNNLQQTLNIVTVQKEV-IDTNLTTLRDGLHGIQRGDIDAMIS 2286
+K LK E+ L+ +KE+ DTN+ ++ + Q+ +D
Sbjct: 1040 LAMEKGLASLKSEMREVEGELE--------RKELEFDTNMDAVQMVITEAQK--VDTRAK 1089
Query: 2287 SAKSMVRKANDITDEVLDGLN-PIQTDVERI-----KDTYGRTQ-NEDFKKALTDADNSV 2339
+A ++ + D +L ++ P+ D E + K + +TQ N + +++ +
Sbjct: 1090 NAGVTIQDTLNTLDGLLHLMDQPLSVDEEGLVLLEQKLSRAKTQINSQLRPMMSELEERA 1149
Query: 2340 NKLTNKLPDLWRKIESINQQLLPLGNISDNM 2370
+ L L I+ I + L NI DN+
Sbjct: 1150 RQQRGHLHLLETSIDGILADVKNLENIRDNL 1180
Score = 120 bits (302), Expect = 2e-26
Identities = 69/201 (34%), Positives = 99/201 (49%), Gaps = 34/201 (16%)
Query: 344 PAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCE 403
PAA S E C+C+G + C +D ++ RQ + G C+NC NT G++CE
Sbjct: 17 PAARATSRR-EVCDCNGKSRQCIFDRELHRQTGN---------GFRCLNCNDNTDGIHCE 66
Query: 404 QCAKGYYRPYGVPVDAPDGCIPCSCDPEHADGCE-QGSGRCHCKPNFHGDNCEKCAIGYY 462
+C G+YR D C+PC+C+ + + SGRC CKP G C++C G++
Sbjct: 67 KCKNGFYRH-----RERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFH 121
Query: 463 NFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDT 522
++D D K CDC+ G+ CDA GRC+C+P V G RCD
Sbjct: 122 ML----------TDAGCTQDQRLLDSK-CDCDPAGIAGP-CDA-GRCVCKPAVTGERCDR 168
Query: 523 CRSGFYSF-----PICQACWC 538
CRSG+Y+ C C+C
Sbjct: 169 CRSGYYNLDGGNPEGCTQCFC 189
Score = 107 bits (268), Expect = 2e-22
Identities = 56/140 (40%), Positives = 73/140 (52%), Gaps = 14/140 (10%)
Query: 508 RCL-CRPGVEGPRCDTCRSGFYSF---PICQACWCSALGSYQMPCSSVTGQCECRPGVTG 563
RCL C +G C+ C++GFY C C C++ GS C + +G+C C+PGVTG
Sbjct: 52 RCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTG 110
Query: 564 QRCDRCLSGAYDFPHCQ--------GSSSACDPAGTINS-NLGYCQCKLHVEGPTCSRCK 614
RCDRCL G + S CDPAG + G C CK V G C RC+
Sbjct: 111 ARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCR 170
Query: 615 LLYWNLDKENPSGCSECKCH 634
Y+NLD NP GC++C C+
Sbjct: 171 SGYYNLDGGNPEGCTQCFCY 190
Score = 98.6 bits (244), Expect = 9e-20
Identities = 58/158 (36%), Positives = 73/158 (46%), Gaps = 22/158 (13%)
Query: 1681 TGRCVPCNCNGHSNQC--------QDGSGI-CVNCQHNTAGEHCERCQEGYYGNAVHGSC 1731
T R C+CNG S QC Q G+G C+NC NT G HCE+C+ G+Y + C
Sbjct: 22 TSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRC 81
Query: 1732 RACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYF-----GNPQKFGGSCQP 1786
C C S + C +G RCSCK G TG +C+RC PG+ G Q
Sbjct: 82 LPCNCNSKGSLSARCDNSG---RCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSK 138
Query: 1787 CSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDS 1824
C C+ G G C G C+ K + E CD C S
Sbjct: 139 CDCDPAGIAGPCD--AGRCV---CKPAVTGERCDRCRS 171
Score = 94.0 bits (232), Expect = 2e-18
Identities = 65/217 (29%), Positives = 87/217 (40%), Gaps = 40/217 (18%)
Query: 1264 LPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPR----CKPCSCGRRL- 1318
+PC C GA C P+ G C +C C G Y P CKPC C
Sbjct: 414 IPCNCQGGGA----CDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFS 469
Query: 1319 CEEMTGQ----CR-CPPRTVRPQCEVCETHSFS-----FHPMAGCEGCNCSRRGTIEAAM 1368
C M C CPP +CE+C F P+ C+ C C+ +A
Sbjct: 470 CSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNN-VDPSAS 528
Query: 1369 PECDRDSGQC-RCKPRITGRQCDRCASGFYRFP-------ECVPCNCNRDGTEPGVCDPG 1420
CDR +G+C +C G CD+C +G++ P +C CNCN G+EP C
Sbjct: 529 GNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGC-RS 587
Query: 1421 TGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCF 1457
G C+CK G C G+F C +C+
Sbjct: 588 DGTCVCKPGFGGPN---CEHGAF--------SCPACY 613
Score = 93.2 bits (230), Expect = 4e-18
Identities = 60/172 (34%), Positives = 77/172 (44%), Gaps = 43/172 (25%)
Query: 437 EQGSG-RC-HCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCN 494
+ G+G RC +C N G +CEKC G+Y R P C+CN
Sbjct: 46 QTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRE--RDRCLP----------------CNCN 87
Query: 495 LEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFP----------ICQACWCSALGSY 544
+G L CD GRC C+PGV G RCD C GF+ + C C G
Sbjct: 88 SKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAG-I 146
Query: 545 QMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFP----------HCQGSSSAC 586
PC + G+C C+P VTG+RCDRC SG Y+ C G S++C
Sbjct: 147 AGPCDA--GRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSASC 196
Score = 91.7 bits (226), Expect = 1e-17
Identities = 73/258 (28%), Positives = 100/258 (38%), Gaps = 68/258 (26%)
Query: 318 RCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHAS------NCYY---D 368
+C C G+ C C +GY + R + C CNC G + +CY +
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGT---CIPCNCQGGGACDPDTGDCYSGDEN 437
Query: 369 PDVERQQASLNTQGIYAGGG-------------------------VCINCQHNTAGVNCE 403
PD+E + G Y VC NC G CE
Sbjct: 438 PDIECADCPI---GFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCE 494
Query: 404 QCAKGYYR-PYGV--PVDAPDGCIPCSC----DPEHADGCEQGSGRC-HCKPNFHGDNCE 455
CA GY+ P+G PV C PC C DP + C++ +GRC C N G C+
Sbjct: 495 LCADGYFGDPFGEHGPVRP---CQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCD 551
Query: 456 KCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGV 515
+C GY+ P P+ D + C+CN G P C + G C+C+PG
Sbjct: 552 QCKAGYFGDPLA----------PNPADKC----RACNCNPMGSEPVGCRSDGTCVCKPGF 597
Query: 516 EGPRCDTCRSGFYSFPIC 533
GP C+ G +S P C
Sbjct: 598 GGPNCE---HGAFSCPAC 612
Score = 89.0 bits (219), Expect = 7e-17
Identities = 62/197 (31%), Positives = 82/197 (41%), Gaps = 24/197 (12%)
Query: 1284 QCPCQPNVIGRQCTRCATGHYG-------FPRCKPCSC-GRRLCEEMTGQCRCPPRTVRP 1335
QC C G+ C CA+G+ F C PC+C G C+ TG C
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDI 440
Query: 1336 QCEVCETHSFSF-HPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCAS 1394
+C C ++ H C+ C C G + MPE + C P +TG +C+ CA
Sbjct: 441 ECADCPIGFYNDPHDPRSCKPCPC-HNGFSCSVMPETEEVVCN-NCPPGVTGARCELCAD 498
Query: 1395 GFYRFP--------ECVPCNCNR--DGTEPGVCDPGTGACL-CKENVEGTECNVCREGSF 1443
G++ P C PC CN D + G CD TG CL C N G C+ C+ G F
Sbjct: 499 GYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYF 558
Query: 1444 --HLDPANLKGCTSCFC 1458
L P C +C C
Sbjct: 559 GDPLAPNPADKCRACNC 575
Score = 87.4 bits (215), Expect = 2e-16
Identities = 74/259 (28%), Positives = 99/259 (38%), Gaps = 76/259 (29%)
Query: 390 CINCQHNTAGVNCEQCAKGYYR------PYGVPVDAPDGCIPCSCDPEHADGCEQGSGRC 443
CI C G C+ CA GY R P+G CIPC+C + C+ +G C
Sbjct: 382 CI-CPVGYKGQFCQDCASGYKRDSARLGPFGT-------CIPCNC--QGGGACDPDTGDC 431
Query: 444 HCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLE---GVLP 500
+ C C IG+YN P DP K C C+ V+P
Sbjct: 432 YSGDENPDIECADCPIGFYNDP---------------HDP--RSCKPCPCHNGFSCSVMP 474
Query: 501 E----ICDAHGRCLCRPGVEGPRCDTCRSGFYSFPI--------CQACWC------SALG 542
E +C+ C PGV G RC+ C G++ P CQ C C SA G
Sbjct: 475 ETEEVVCNN-----CPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASG 529
Query: 543 SYQMPCSSVTGQC-ECRPGVTGQRCDRCLSGAYDFPHCQGSSSAC----------DPAGT 591
+ C +TG+C +C G CD+C +G + P + C +P G
Sbjct: 530 N----CDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGC 585
Query: 592 INSNLGYCQCKLHVEGPTC 610
+ G C CK GP C
Sbjct: 586 RSD--GTCVCKPGFGGPNC 602
Score = 75.1 bits (183), Expect = 1e-12
Identities = 52/171 (30%), Positives = 73/171 (42%), Gaps = 22/171 (12%)
Query: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 358
C C+ + E++ C G C+ C GY + C+ C C
Sbjct: 462 CPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPF--GEHGPVRPCQPCQC 519
Query: 359 HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVD 418
+ + DP AS N + G C+ C HNTAG+ C+QC GY+ P
Sbjct: 520 NNNV-----DP-----SASGNCDRL---TGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNP 566
Query: 419 APDGCIPCSCDPEHAD--GCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFC 467
A D C C+C+P ++ GC + G C CKP F G NCE G ++ P C
Sbjct: 567 A-DKCRACNCNPMGSEPVGC-RSDGTCVCKPGFGGPNCEH---GAFSCPAC 612
Score = 74.3 bits (181), Expect = 2e-12
Identities = 70/246 (28%), Positives = 92/246 (37%), Gaps = 46/246 (18%)
Query: 442 RCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVL-P 500
+C C + G C+ CA GY R+ F P C+C G P
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDS--ARLGPFGTCIP------------CNCQGGGACDP 426
Query: 501 EICDAHGRCLCRPGVEGP--RCDTCRSGFYSFP----ICQACWC-SALGSYQMPCSSVTG 553
+ D C G E P C C GFY+ P C+ C C + MP +
Sbjct: 427 DTGD------CYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVV 480
Query: 554 QCECRPGVTGQRCDRCLSGAYDFPHCQ-GSSSACDP-----------AGTINSNLGYC-Q 600
C PGVTG RC+ C G + P + G C P +G + G C +
Sbjct: 481 CNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLK 540
Query: 601 CKLHVEGPTCSRCKLLYWN--LDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHV 658
C + G C +CK Y+ L C C C+ G S CR DG C CK
Sbjct: 541 CIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMG--SEPVGCR-SDGTCVCKPGF 597
Query: 659 GGDSCD 664
GG +C+
Sbjct: 598 GGPNCE 603
Score = 73.6 bits (179), Expect = 3e-12
Identities = 52/177 (29%), Positives = 73/177 (41%), Gaps = 41/177 (23%)
Query: 1256 VAFYH-----KGALPCECHPTGATGPHCS--PEGGQCPCQ---PNVIGRQCTRCATGHYG 1305
+ FY+ + PC CH G CS PE + C P V G +C CA G++G
Sbjct: 447 IGFYNDPHDPRSCKPCPCH----NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFG 502
Query: 1306 FP--------RCKPCSCGRRL-------CEEMTGQC-RCPPRTVRPQCEVCETHSF---- 1345
P C+PC C + C+ +TG+C +C T C+ C+ F
Sbjct: 503 DPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPL 562
Query: 1346 SFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPEC 1402
+ +P C CNC+ G + P R G C CKP G C+ G + P C
Sbjct: 563 APNPADKCRACNCNPMG----SEPVGCRSDGTCVCKPGFGGPNCEH---GAFSCPAC 612
Score = 68.6 bits (166), Expect = 1e-10
Identities = 46/144 (31%), Positives = 62/144 (43%), Gaps = 24/144 (16%)
Query: 557 CRPGVTGQRCDRCLSGAY---DFPHCQGSSSACDPAGTINS---NLGYCQCKLHVEGPTC 610
C G C++C +G Y + C + C+ G++++ N G C CK V G C
Sbjct: 56 CNDNTDGIHCEKCKNGFYRHRERDRCLPCN--CNSKGSLSARCDNSGRCSCKPGVTGARC 113
Query: 611 SRCKLLYWNLDKENPSGC--------SECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDS 662
RC + L +GC S+C C AG G C G C CK V G+
Sbjct: 114 DRCLPGFHML---TDAGCTQDQRLLDSKCDCDPAGIA---GPCDAGR--CVCKPAVTGER 165
Query: 663 CDTCEDGYFALEKSNYFGCQGCQC 686
CD C GY+ L+ N GC C C
Sbjct: 166 CDRCRSGYYNLDGGNPEGCTQCFC 189
Score = 67.4 bits (163), Expect = 2e-10
Identities = 50/180 (27%), Positives = 71/180 (39%), Gaps = 13/180 (7%)
Query: 554 QCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPA-----GTINSNLGYCQCKLHVEGP 608
QC C G GQ C C SG G C P G + + G C
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDI 440
Query: 609 TCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCED 668
C+ C + ++N D +P C C CH + S E + + +C V G C+ C D
Sbjct: 441 ECADCPIGFYN-DPHDPRSCKPCPCHNGFSCSVMPETEEVVCN-NCPPGVTGARCELCAD 498
Query: 669 GYFA---LEKSNYFGCQGCQC--DIGGALSSMCSGPSGVC-QCREHVVGKVCQRPENNYY 722
GYF E CQ CQC ++ + S C +G C +C + G C + + Y+
Sbjct: 499 GYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYF 558
Score = 58.2 bits (139), Expect = 1e-07
Identities = 42/156 (26%), Positives = 63/156 (40%), Gaps = 23/156 (14%)
Query: 579 CQGSSSACDPAGTINSNLGY----CQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCH 634
C G S C ++ G C + +G C +CK ++ + + C C C+
Sbjct: 30 CNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR--CLPCNCN 87
Query: 635 KAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGC--------QGCQC 686
G++S + G C CK V G CD C G+ L + GC C C
Sbjct: 88 SKGSLSARCD---NSGRCSCKPGVTGARCDRCLPGFHMLTDA---GCTQDQRLLDSKCDC 141
Query: 687 DIGGALSSMCSGPSGVCQCREHVVGKVCQRPENNYY 722
D G ++ C +G C C+ V G+ C R + YY
Sbjct: 142 DPAG-IAGPCD--AGRCVCKPAVTGERCDRCRSGYY 174
Score = 53.1 bits (126), Expect = 4e-06
Identities = 23/62 (37%), Positives = 32/62 (51%), Gaps = 3/62 (4%)
Query: 1266 CECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCGRRLCEEMTGQ 1325
C+C P G GP C + G+C C+P V G +C RC +G+Y P C + C +
Sbjct: 139 CDCDPAGIAGP-C--DAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSAS 195
Query: 1326 CR 1327
CR
Sbjct: 196 CR 197
Score = 45.8 bits (107), Expect = 7e-04
Identities = 34/130 (26%), Positives = 45/130 (34%), Gaps = 33/130 (25%)
Query: 308 CNINNPEKLF-------RCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCH- 359
CN N+ L RC C+ G CDRC G++ +Q C+C
Sbjct: 84 CNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDP 143
Query: 360 -GHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVD 418
G A C G C+ C+ G C++C GYY G
Sbjct: 144 AGIAGPC--------------------DAGRCV-CKPAVTGERCDRCRSGYYNLDG---G 179
Query: 419 APDGCIPCSC 428
P+GC C C
Sbjct: 180 NPEGCTQCFC 189
Score = 40.8 bits (94), Expect = 0.023
Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 11/72 (15%)
Query: 295 IGGQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTG-YNQRRWRPAAWEQSHEC 353
+ +C C + I P RC C+ GE CDRC +G YN P C
Sbjct: 135 LDSKCDC----DPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEG------C 184
Query: 354 EACNCHGHASNC 365
C C+GH+++C
Sbjct: 185 TQCFCYGHSASC 196
>gi|93204871 netrin 4 [Homo sapiens]
Length = 628
Score = 239 bits (610), Expect = 3e-62
Identities = 158/494 (31%), Positives = 226/494 (45%), Gaps = 71/494 (14%)
Query: 26 LRVLPACGATARDPGAAAGLS------LHPTYFNLAEAARIWATATCGERGPGEGRPQPE 79
L +L C A AG+S +P NLA ++WA TCG+ E
Sbjct: 7 LLLLWGCTVVAAGLSGVAGVSSRCEKACNPRMGNLALGRKLWADTTCGQNAT-------E 59
Query: 80 LYCKLVGGPTAPGSGHTIQGQFCDYCNSEDPRKAHPVTNAIDGSER----WWQSPPLSSG 135
LYC + + T + CD CN+ P AH + D S R WWQS
Sbjct: 60 LYCFY-----SENTDLTCRQPKCDKCNAAYPHLAHLPSAMADSSFRFPRTWWQS-----A 109
Query: 136 TQYNRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVDFGSTYSPWQYFAHSKVDCL 195
+R + LDL F+ ++++ F SPRP VL+RS DFG T+ P++YFA +C
Sbjct: 110 EDVHREKIQLDLEAEFYFTHLIVMF-KSPRPAAMVLDRSQDFGKTWKPYKYFA---TNCS 165
Query: 196 KEFGREANMAVTRDDDVLCVTEYSRIVPLENGEVVVSLINGRPGAKNFTFSHTLREFTKA 255
FG E ++ +C ++YS P GEV+ ++ +N +S ++E K
Sbjct: 166 ATFGLEDDVV---KKGAICTSKYSSPFPCTGGEVIFKALSPPYDTEN-PYSAKVQEQLKI 221
Query: 256 TNIRLRFLRTNTLLGHLISKAQRDPTVTRRYYYSIKDISIGGQCVCNGHAEVC------- 308
TN+R++ L+ + + T +Y+I D + G C CNGHA+ C
Sbjct: 222 TNLRVQLLKRQSCPCQRNDLNEEPQHFT---HYAIYDFIVKGSCFCNGHADQCIPVHGFR 278
Query: 309 NINNPEKLF----RCECQHHTCGETCDRCCTGYNQRRWRPAAWEQS--HECEACNCHGHA 362
+ P +C C+H+T G C C YN R W A + +EC C C+GHA
Sbjct: 279 PVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHA 338
Query: 363 SNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDG 422
C++D +V +AS N G GVC +CQHNT G C++C G+YR P APD
Sbjct: 339 DTCHFDVNV--WEASGNRSG-----GVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDA 391
Query: 423 CIPCSCDP--------EHADGCEQGSGRCHCKPNFHGDNCEKCAIGYYNF-PFCLRIPIF 473
C PCSC P C+ +G C CKP G C++C +GY+ F + R
Sbjct: 392 CKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCR---- 447
Query: 474 PVSTPSSEDPVAGD 487
P S DP+ GD
Sbjct: 448 PCDCAGSCDPITGD 461
Score = 115 bits (289), Expect = 6e-25
Identities = 65/183 (35%), Positives = 86/183 (46%), Gaps = 40/183 (21%)
Query: 1654 CACPPAYAGDSCQGCSPGYY------RDHKGLYTGRCVPCNCNGHSNQCQ---------- 1697
C C AG CQ C+P Y D K C C CNGH++ C
Sbjct: 293 CMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASG 352
Query: 1698 -DGSGICVNCQHNTAGEHCERCQEGYYGN-----AVHGSCRACPCPHTNS------FATG 1745
G+C +CQHNT G++C+RC+ G+Y + + +C+ C C S T
Sbjct: 353 NRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTF 412
Query: 1746 CVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGG-SCQPCSCNSNGQLGSCHPLTGD 1804
C + GD C CK G G +C+RC GY+G FG C+PC C GSC P+TGD
Sbjct: 413 CDPSNGD--CPCKPGVAGRRCDRCMVGYWG----FGDYGCRPCDC-----AGSCDPITGD 461
Query: 1805 CIN 1807
CI+
Sbjct: 462 CIS 464
Score = 90.1 bits (222), Expect = 3e-17
Identities = 76/261 (29%), Positives = 102/261 (39%), Gaps = 75/261 (28%)
Query: 355 ACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYY-RPY 413
+C C+GHA C +A ++ G C+ C+HNTAG +C+ CA Y RP+
Sbjct: 261 SCFCNGHADQCIPVHGFRPVKAPGTFHMVH---GKCM-CKHNTAGSHCQHCAPLYNDRPW 316
Query: 414 GVPVDAPDGCIPCSCDPEHADGCEQGSGRCH-CKPNFHGDNCEKCAIGYYNFPFCLRIPI 472
E ADG C CK N H D C
Sbjct: 317 -----------------EAADGKTGAPNECRTCKCNGHADTCH----------------- 342
Query: 473 FPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFY---- 528
F V+ + +G + CD C+ EG C C+ GFY
Sbjct: 343 FDVNVWEASGNRSGGV--------------CDD-----CQHNTEGQYCQRCKPGFYRDLR 383
Query: 529 ---SFP-ICQACWCSALGSYQMPCSSVT------GQCECRPGVTGQRCDRCLSGAYDFPH 578
S P C+ C C +GS +P +SVT G C C+PGV G+RCDRC+ G + F
Sbjct: 384 RPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFG- 442
Query: 579 CQGSSSACDPAGTINSNLGYC 599
CD AG+ + G C
Sbjct: 443 -DYGCRPCDCAGSCDPITGDC 462
Score = 80.5 bits (197), Expect = 3e-14
Identities = 83/329 (25%), Positives = 125/329 (37%), Gaps = 84/329 (25%)
Query: 1157 FHASFCPHVLGCRDQVIAEGQIEFDISEPEVAATVKVPEGKSLVLVRVLVVPAENYDYQI 1216
+ A+ C G D V+ +G I + ++ G+ V+ + L P YD +
Sbjct: 159 YFATNCSATFGLEDDVVKKGAI----CTSKYSSPFPCTGGE--VIFKALSPP---YDTEN 209
Query: 1217 LHKKSMDKSLEFITN------------CGKNSFYLDPQTASRFCKNSARSLVAFYHKGAL 1264
+ + + L+ ITN C +N +PQ + + ++ F KG+
Sbjct: 210 PYSAKVQEQLK-ITNLRVQLLKRQSCPCQRNDLNEEPQHFTHY------AIYDFIVKGSC 262
Query: 1265 PC-----ECHPTGATGPHCSPEG-----GQCPCQPNVIGRQCTRCAT-----------GH 1303
C +C P P +P G+C C+ N G C CA G
Sbjct: 263 FCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGK 322
Query: 1304 YGFPR-CKPCSCGRRL--CE-----------EMTGQCR-CPPRTVRPQCEVCETHSFS-- 1346
G P C+ C C C G C C T C+ C+ +
Sbjct: 323 TGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDL 382
Query: 1347 ---FHPMAGCEGCNCSRRGTIEAAMPE-----CDRDSGQCRCKPRITGRQCDRCASGFYR 1398
F C+ C+C G+ A +P CD +G C CKP + GR+CDRC G++
Sbjct: 383 RRPFSAPDACKPCSCHPVGS--AVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWG 440
Query: 1399 FPE--CVPCNCNRDGTEPGVCDPGTGACL 1425
F + C PC+C G CDP TG C+
Sbjct: 441 FGDYGCRPCDC------AGSCDPITGDCI 463
Score = 73.2 bits (178), Expect = 4e-12
Identities = 54/189 (28%), Positives = 72/189 (38%), Gaps = 35/189 (18%)
Query: 506 HGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQR 565
HG+C+C+ G C C + P W +A G P ECR
Sbjct: 290 HGKCMCKHNTAGSHCQHCAPLYNDRP-----WEAADGKTGAPN-------ECRTCKCNGH 337
Query: 566 CDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQ-CKLHVEGPTCSRCKL-LYWNLDK- 622
D C +D + S N + G C C+ + EG C RCK Y +L +
Sbjct: 338 ADTC---HFDVNVWEASG---------NRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRP 385
Query: 623 -ENPSGCSECKCHKAGTV----SGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSN 677
P C C CH G+ + C +GDC CK V G CD C GY+
Sbjct: 386 FSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGF---G 442
Query: 678 YFGCQGCQC 686
+GC+ C C
Sbjct: 443 DYGCRPCDC 451
Score = 70.9 bits (172), Expect = 2e-11
Identities = 51/180 (28%), Positives = 66/180 (36%), Gaps = 51/180 (28%)
Query: 1687 CNCNGHSNQCQDGSGI---------------CVNCQHNTAGEHCERCQEGYYG------- 1724
C CNGH++QC G C+ C+HNTAG HC+ C Y
Sbjct: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCM-CKHNTAGSHCQHCAPLYNDRPWEAAD 320
Query: 1725 --NAVHGSCRACPCPHTNSFATGCVVN----------GGDVRCSCKAGYTGTQCERCAPG 1772
CR C C N A C + G V C+ G C+RC PG
Sbjct: 321 GKTGAPNECRTCKC---NGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPG 377
Query: 1773 YFGN---PQKFGGSCQPCSCNSNG-------QLGSCHPLTGDCINQEPKDSSPAEECDDC 1822
++ + P +C+PCSC+ G + C P GDC K CD C
Sbjct: 378 FYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDC---PCKPGVAGRRCDRC 434
Score = 55.1 bits (131), Expect = 1e-06
Identities = 44/176 (25%), Positives = 64/176 (36%), Gaps = 32/176 (18%)
Query: 579 CQGSSSACDPA---------GTINSNLGYCQCKLHVEGPTCSRCKLLYWNLDKEN----- 624
C G + C P GT + G C CK + G C C LY + E
Sbjct: 264 CNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKT 323
Query: 625 --PSGCSECKC-------HKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEK 675
P+ C CKC H V R G C+ + G C C+ G++ +
Sbjct: 324 GAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLR 383
Query: 676 SNYFG---CQGCQCD-IGGALS-----SMCSGPSGVCQCREHVVGKVCQRPENNYY 722
+ C+ C C +G A+ + C +G C C+ V G+ C R Y+
Sbjct: 384 RPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYW 439
Score = 42.7 bits (99), Expect = 0.006
Identities = 38/135 (28%), Positives = 49/135 (36%), Gaps = 26/135 (19%)
Query: 1706 CQHNTAGEHCERCQE-GYYGNAVHGSC----RACPCPHTNSF------ATGCVVNGGDVR 1754
CQ N E + Y V GSC A C + F T +V+G +
Sbjct: 236 CQRNDLNEEPQHFTHYAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHMVHG---K 292
Query: 1755 CSCKAGYTGTQCERCAPGYFGNPQKFG-------GSCQPCSCNSNGQLGSCHPLTGDCIN 1807
C CK G+ C+ CAP Y P + C+ C C NG +CH D
Sbjct: 293 CMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKC--NGHADTCH---FDVNV 347
Query: 1808 QEPKDSSPAEECDDC 1822
E + CDDC
Sbjct: 348 WEASGNRSGGVCDDC 362
Score = 35.4 bits (80), Expect = 0.95
Identities = 21/73 (28%), Positives = 30/73 (41%), Gaps = 7/73 (9%)
Query: 1401 ECVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCRE--GSFHLDPANLK-----GC 1453
+C+P + R PG G C+CK N G+ C C + A+ K C
Sbjct: 270 QCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNEC 329
Query: 1454 TSCFCFGVNNQCH 1466
+C C G + CH
Sbjct: 330 RTCKCNGHADTCH 342
>gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens]
Length = 1111
Score = 235 bits (600), Expect = 5e-61
Identities = 274/1077 (25%), Positives = 442/1077 (41%), Gaps = 165/1077 (15%)
Query: 1328 CPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGR 1387
C T CE C+ + C CNC+ +G++ A CD +SG+C CKP +TG
Sbjct: 56 CNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSA---RCD-NSGRCSCKPGVTGA 111
Query: 1388 QCDRCASGFYRFPEC----------VPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNV 1437
+CDRC GF+ + C+C+ G G CD G C+CK V G C+
Sbjct: 112 RCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIA-GPCD--AGRCVCKPAVTGERCDR 168
Query: 1438 CREGSFHLDPANLKGCTSCFCFGVNNQCHSS-----HKRRTKF-VDMLGWHLETADRVDI 1491
CR G ++LD N +GCT CFC+G + C SS HK + F D+ GW +
Sbjct: 169 CRSGYYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSPA 228
Query: 1492 PVSFNPGSNSMVADLQELPATIHSASWVAPTSYLGDKVSSYGGYLTYQAKSFGLPGDMVL 1551
+ ++ + + Q L +VAP +LG++ SYG Q+ SF D
Sbjct: 229 KLQWSQRHQDVFSSAQRLDPVY----FVAPAKFLGNQQVSYG-----QSLSFDYRVDRGG 279
Query: 1552 LEKKP-DVQLTGQHMSIIYEETNTPRPDRLHHGRVHVVEGNFRHASSRAP-VSREELMTV 1609
DV L G + I + + + N +++ +P +S E +
Sbjct: 280 RHPSAHDVILEGAGLRITAPLMPLGKTLPCGLTKTYTFRLNEHPSNNWSPQLSYFEYRRL 339
Query: 1610 LSRLADVRIQGLYFTETQRLTLSEVGLEEASDTGSGRIALAVEICACPPAYAGDSCQGCS 1669
L L +RI+ Y E + V L A SG A VE C CP Y G CQ C+
Sbjct: 340 LRNLTALRIRATY-GEYSTGYIDNVTLISARPV-SGAPAPWVEQCICPVGYKGQFCQDCA 397
Query: 1670 PGYYRDHKGLYT-GRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVH 1728
GY RD L G C+PCNC G C +G C + N E C C G+Y N H
Sbjct: 398 SGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYSGDENPDIE-CADCPIGFY-NDPH 454
Query: 1729 G--SCRACPCPHTNSFATGCVVNGGDVRCS-CKAGYTGTQCERCAPGYFGNPQKFGG--- 1782
SC+ CPC N F+ + +V C+ C G TG +CE CA GYFG+P G
Sbjct: 455 DPRSCKPCPCH--NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVR 512
Query: 1783 SCQPCSCNSN---GQLGSCHPLTGDCIN------------------QEPKDSSPAEECDD 1821
CQPC CN+N G+C LTG C+ +P +PA++C
Sbjct: 513 PCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRA 572
Query: 1822 CDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAI 1881
C +C + + + K G + G Q K +Q + +
Sbjct: 573 C-NCNPMGSEPVGCRSDGTCVCKPGFGGPNCEHGAF-SCPACYNQVKIQMDQFMQQLQRM 630
Query: 1882 SNHGSKIEG---------LERELTDLNQEFETLQEKAQVNSRKAQTLN------------ 1920
SK +G LE + Q + + AQ++ +++L
Sbjct: 631 EALISKAQGGDGVVPDTELEGRMQQAEQALQDILRDAQISEGASRSLGLQLAKVRSQENS 690
Query: 1921 -----NNVNRATQSAKELDVKIKNVIRNVHILLKQISGTDGE-----GN-NVPSGD---- 1965
+++ + + L + +N +R+ H L+ Q+ + E GN N+P+ D
Sbjct: 691 YQSRLDDLKMTVERVRALGSQYQNRVRDTHRLITQMQLSLAESEASLGNTNIPASDHYVG 750
Query: 1966 ---FSREWAEAQRMMRE--LRNRNFGKHLREAEADKRESQLLLNRIRTWQKTHQGENNGL 2020
F EA R+ N + RE E +++ L+ + H+G +G
Sbjct: 751 PNGFKSLAQEATRLAESHVESASNMEQLTRETEDYSKQALSLVRK-----ALHEGVGSGS 805
Query: 2021 AN---SIRDSLNEYEAKLSDLRARLQEAAAQAK-QANGLNQENERALGAIQR-QVKEINS 2075
+ ++ L E K L +L A QA+ +A+ Q + R L ++ R Q S
Sbjct: 806 GSPDGAVVQGLVEKLEKTKSLAQQLTREATQAEIEADRSYQHSLRLLDSVSRLQGVSDQS 865
Query: 2076 LQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQ---------ELSDKV 2126
Q + K + SL +++ + M++ ++ + L EA+Q E SD++
Sbjct: 866 FQVEEAKRIKQKADSL--SSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQL 923
Query: 2127 ---RELSRSAGKTSL------VEEAEKHARSLQELAKQLEEIKRNASGDELVR------- 2170
L++S + +L E E ++L+E Q++ R A +E ++
Sbjct: 924 LSRANLAKSRAQEALSMGNATFYEVESILKNLREFDLQVD--NRKAEAEEAMKRLSYISQ 981
Query: 2171 CAVDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEA 2230
DA+ + A+ +A A RA + + AL+ I ++ ++ +L+ ++ + A
Sbjct: 982 KVSDASDKTQQAERALGSAAADAQRAKNGAGEALE--ISSEIEQEIGSLNLEANVTADGA 1039
Query: 2231 KMTQK---KLKQEVSPALNNLQQTLNIVTVQKEV-IDTNLTTLRDGLHGIQRGDIDA 2283
+K LK E+ L+ +KE+ DTN+ ++ + Q+ D A
Sbjct: 1040 LAMEKGLASLKSEMREVEGELE--------RKELEFDTNMDAVQMVITEAQKVDTRA 1088
Score = 120 bits (302), Expect = 2e-26
Identities = 69/201 (34%), Positives = 99/201 (49%), Gaps = 34/201 (16%)
Query: 344 PAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCE 403
PAA S E C+C+G + C +D ++ RQ + G C+NC NT G++CE
Sbjct: 17 PAARATSRR-EVCDCNGKSRQCIFDRELHRQTGN---------GFRCLNCNDNTDGIHCE 66
Query: 404 QCAKGYYRPYGVPVDAPDGCIPCSCDPEHADGCE-QGSGRCHCKPNFHGDNCEKCAIGYY 462
+C G+YR D C+PC+C+ + + SGRC CKP G C++C G++
Sbjct: 67 KCKNGFYRH-----RERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFH 121
Query: 463 NFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDT 522
++D D K CDC+ G+ CDA GRC+C+P V G RCD
Sbjct: 122 ML----------TDAGCTQDQRLLDSK-CDCDPAGIAGP-CDA-GRCVCKPAVTGERCDR 168
Query: 523 CRSGFYSF-----PICQACWC 538
CRSG+Y+ C C+C
Sbjct: 169 CRSGYYNLDGGNPEGCTQCFC 189
Score = 107 bits (268), Expect = 2e-22
Identities = 56/140 (40%), Positives = 73/140 (52%), Gaps = 14/140 (10%)
Query: 508 RCL-CRPGVEGPRCDTCRSGFYSF---PICQACWCSALGSYQMPCSSVTGQCECRPGVTG 563
RCL C +G C+ C++GFY C C C++ GS C + +G+C C+PGVTG
Sbjct: 52 RCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTG 110
Query: 564 QRCDRCLSGAYDFPHCQ--------GSSSACDPAGTINS-NLGYCQCKLHVEGPTCSRCK 614
RCDRCL G + S CDPAG + G C CK V G C RC+
Sbjct: 111 ARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCR 170
Query: 615 LLYWNLDKENPSGCSECKCH 634
Y+NLD NP GC++C C+
Sbjct: 171 SGYYNLDGGNPEGCTQCFCY 190
Score = 98.6 bits (244), Expect = 9e-20
Identities = 58/158 (36%), Positives = 73/158 (46%), Gaps = 22/158 (13%)
Query: 1681 TGRCVPCNCNGHSNQC--------QDGSGI-CVNCQHNTAGEHCERCQEGYYGNAVHGSC 1731
T R C+CNG S QC Q G+G C+NC NT G HCE+C+ G+Y + C
Sbjct: 22 TSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRC 81
Query: 1732 RACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYF-----GNPQKFGGSCQP 1786
C C S + C +G RCSCK G TG +C+RC PG+ G Q
Sbjct: 82 LPCNCNSKGSLSARCDNSG---RCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSK 138
Query: 1787 CSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDS 1824
C C+ G G C G C+ K + E CD C S
Sbjct: 139 CDCDPAGIAGPCD--AGRCV---CKPAVTGERCDRCRS 171
Score = 94.0 bits (232), Expect = 2e-18
Identities = 65/217 (29%), Positives = 87/217 (40%), Gaps = 40/217 (18%)
Query: 1264 LPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPR----CKPCSCGRRL- 1318
+PC C GA C P+ G C +C C G Y P CKPC C
Sbjct: 414 IPCNCQGGGA----CDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFS 469
Query: 1319 CEEMTGQ----CR-CPPRTVRPQCEVCETHSFS-----FHPMAGCEGCNCSRRGTIEAAM 1368
C M C CPP +CE+C F P+ C+ C C+ +A
Sbjct: 470 CSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNN-VDPSAS 528
Query: 1369 PECDRDSGQC-RCKPRITGRQCDRCASGFYRFP-------ECVPCNCNRDGTEPGVCDPG 1420
CDR +G+C +C G CD+C +G++ P +C CNCN G+EP C
Sbjct: 529 GNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGC-RS 587
Query: 1421 TGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCF 1457
G C+CK G C G+F C +C+
Sbjct: 588 DGTCVCKPGFGGPN---CEHGAF--------SCPACY 613
Score = 93.2 bits (230), Expect = 4e-18
Identities = 60/172 (34%), Positives = 77/172 (44%), Gaps = 43/172 (25%)
Query: 437 EQGSG-RC-HCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCN 494
+ G+G RC +C N G +CEKC G+Y R P C+CN
Sbjct: 46 QTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRE--RDRCLP----------------CNCN 87
Query: 495 LEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFP----------ICQACWCSALGSY 544
+G L CD GRC C+PGV G RCD C GF+ + C C G
Sbjct: 88 SKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAG-I 146
Query: 545 QMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFP----------HCQGSSSAC 586
PC + G+C C+P VTG+RCDRC SG Y+ C G S++C
Sbjct: 147 AGPCDA--GRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSASC 196
Score = 91.7 bits (226), Expect = 1e-17
Identities = 73/258 (28%), Positives = 100/258 (38%), Gaps = 68/258 (26%)
Query: 318 RCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHAS------NCYY---D 368
+C C G+ C C +GY + R + C CNC G + +CY +
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGT---CIPCNCQGGGACDPDTGDCYSGDEN 437
Query: 369 PDVERQQASLNTQGIYAGGG-------------------------VCINCQHNTAGVNCE 403
PD+E + G Y VC NC G CE
Sbjct: 438 PDIECADCPI---GFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCE 494
Query: 404 QCAKGYYR-PYGV--PVDAPDGCIPCSC----DPEHADGCEQGSGRC-HCKPNFHGDNCE 455
CA GY+ P+G PV C PC C DP + C++ +GRC C N G C+
Sbjct: 495 LCADGYFGDPFGEHGPVRP---CQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCD 551
Query: 456 KCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGV 515
+C GY+ P P+ D + C+CN G P C + G C+C+PG
Sbjct: 552 QCKAGYFGDPLA----------PNPADKC----RACNCNPMGSEPVGCRSDGTCVCKPGF 597
Query: 516 EGPRCDTCRSGFYSFPIC 533
GP C+ G +S P C
Sbjct: 598 GGPNCE---HGAFSCPAC 612
Score = 89.0 bits (219), Expect = 7e-17
Identities = 62/197 (31%), Positives = 82/197 (41%), Gaps = 24/197 (12%)
Query: 1284 QCPCQPNVIGRQCTRCATGHYG-------FPRCKPCSC-GRRLCEEMTGQCRCPPRTVRP 1335
QC C G+ C CA+G+ F C PC+C G C+ TG C
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDI 440
Query: 1336 QCEVCETHSFSF-HPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCAS 1394
+C C ++ H C+ C C G + MPE + C P +TG +C+ CA
Sbjct: 441 ECADCPIGFYNDPHDPRSCKPCPC-HNGFSCSVMPETEEVVCN-NCPPGVTGARCELCAD 498
Query: 1395 GFYRFP--------ECVPCNCNR--DGTEPGVCDPGTGACL-CKENVEGTECNVCREGSF 1443
G++ P C PC CN D + G CD TG CL C N G C+ C+ G F
Sbjct: 499 GYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYF 558
Query: 1444 --HLDPANLKGCTSCFC 1458
L P C +C C
Sbjct: 559 GDPLAPNPADKCRACNC 575
Score = 87.4 bits (215), Expect = 2e-16
Identities = 74/259 (28%), Positives = 99/259 (38%), Gaps = 76/259 (29%)
Query: 390 CINCQHNTAGVNCEQCAKGYYR------PYGVPVDAPDGCIPCSCDPEHADGCEQGSGRC 443
CI C G C+ CA GY R P+G CIPC+C + C+ +G C
Sbjct: 382 CI-CPVGYKGQFCQDCASGYKRDSARLGPFGT-------CIPCNC--QGGGACDPDTGDC 431
Query: 444 HCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLE---GVLP 500
+ C C IG+YN P DP K C C+ V+P
Sbjct: 432 YSGDENPDIECADCPIGFYNDP---------------HDP--RSCKPCPCHNGFSCSVMP 474
Query: 501 E----ICDAHGRCLCRPGVEGPRCDTCRSGFYSFPI--------CQACWC------SALG 542
E +C+ C PGV G RC+ C G++ P CQ C C SA G
Sbjct: 475 ETEEVVCNN-----CPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASG 529
Query: 543 SYQMPCSSVTGQC-ECRPGVTGQRCDRCLSGAYDFPHCQGSSSAC----------DPAGT 591
+ C +TG+C +C G CD+C +G + P + C +P G
Sbjct: 530 N----CDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGC 585
Query: 592 INSNLGYCQCKLHVEGPTC 610
+ G C CK GP C
Sbjct: 586 RSD--GTCVCKPGFGGPNC 602
Score = 75.1 bits (183), Expect = 1e-12
Identities = 52/171 (30%), Positives = 73/171 (42%), Gaps = 22/171 (12%)
Query: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 358
C C+ + E++ C G C+ C GY + C+ C C
Sbjct: 462 CPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPF--GEHGPVRPCQPCQC 519
Query: 359 HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVD 418
+ + DP AS N + G C+ C HNTAG+ C+QC GY+ P
Sbjct: 520 NNNV-----DP-----SASGNCDRL---TGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNP 566
Query: 419 APDGCIPCSCDPEHAD--GCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFC 467
A D C C+C+P ++ GC + G C CKP F G NCE G ++ P C
Sbjct: 567 A-DKCRACNCNPMGSEPVGC-RSDGTCVCKPGFGGPNCEH---GAFSCPAC 612
Score = 74.3 bits (181), Expect = 2e-12
Identities = 70/246 (28%), Positives = 92/246 (37%), Gaps = 46/246 (18%)
Query: 442 RCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVL-P 500
+C C + G C+ CA GY R+ F P C+C G P
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDS--ARLGPFGTCIP------------CNCQGGGACDP 426
Query: 501 EICDAHGRCLCRPGVEGP--RCDTCRSGFYSFP----ICQACWC-SALGSYQMPCSSVTG 553
+ D C G E P C C GFY+ P C+ C C + MP +
Sbjct: 427 DTGD------CYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVV 480
Query: 554 QCECRPGVTGQRCDRCLSGAYDFPHCQ-GSSSACDP-----------AGTINSNLGYC-Q 600
C PGVTG RC+ C G + P + G C P +G + G C +
Sbjct: 481 CNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLK 540
Query: 601 CKLHVEGPTCSRCKLLYWN--LDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHV 658
C + G C +CK Y+ L C C C+ G S CR DG C CK
Sbjct: 541 CIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMG--SEPVGCR-SDGTCVCKPGF 597
Query: 659 GGDSCD 664
GG +C+
Sbjct: 598 GGPNCE 603
Score = 73.6 bits (179), Expect = 3e-12
Identities = 52/177 (29%), Positives = 73/177 (41%), Gaps = 41/177 (23%)
Query: 1256 VAFYH-----KGALPCECHPTGATGPHCS--PEGGQCPCQ---PNVIGRQCTRCATGHYG 1305
+ FY+ + PC CH G CS PE + C P V G +C CA G++G
Sbjct: 447 IGFYNDPHDPRSCKPCPCH----NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFG 502
Query: 1306 FP--------RCKPCSCGRRL-------CEEMTGQC-RCPPRTVRPQCEVCETHSF---- 1345
P C+PC C + C+ +TG+C +C T C+ C+ F
Sbjct: 503 DPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPL 562
Query: 1346 SFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPEC 1402
+ +P C CNC+ G + P R G C CKP G C+ G + P C
Sbjct: 563 APNPADKCRACNCNPMG----SEPVGCRSDGTCVCKPGFGGPNCEH---GAFSCPAC 612
Score = 68.6 bits (166), Expect = 1e-10
Identities = 46/144 (31%), Positives = 62/144 (43%), Gaps = 24/144 (16%)
Query: 557 CRPGVTGQRCDRCLSGAY---DFPHCQGSSSACDPAGTINS---NLGYCQCKLHVEGPTC 610
C G C++C +G Y + C + C+ G++++ N G C CK V G C
Sbjct: 56 CNDNTDGIHCEKCKNGFYRHRERDRCLPCN--CNSKGSLSARCDNSGRCSCKPGVTGARC 113
Query: 611 SRCKLLYWNLDKENPSGC--------SECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDS 662
RC + L +GC S+C C AG G C G C CK V G+
Sbjct: 114 DRCLPGFHML---TDAGCTQDQRLLDSKCDCDPAGIA---GPCDAGR--CVCKPAVTGER 165
Query: 663 CDTCEDGYFALEKSNYFGCQGCQC 686
CD C GY+ L+ N GC C C
Sbjct: 166 CDRCRSGYYNLDGGNPEGCTQCFC 189
Score = 67.4 bits (163), Expect = 2e-10
Identities = 50/180 (27%), Positives = 71/180 (39%), Gaps = 13/180 (7%)
Query: 554 QCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPA-----GTINSNLGYCQCKLHVEGP 608
QC C G GQ C C SG G C P G + + G C
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDI 440
Query: 609 TCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCED 668
C+ C + ++N D +P C C CH + S E + + +C V G C+ C D
Sbjct: 441 ECADCPIGFYN-DPHDPRSCKPCPCHNGFSCSVMPETEEVVCN-NCPPGVTGARCELCAD 498
Query: 669 GYFA---LEKSNYFGCQGCQC--DIGGALSSMCSGPSGVC-QCREHVVGKVCQRPENNYY 722
GYF E CQ CQC ++ + S C +G C +C + G C + + Y+
Sbjct: 499 GYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYF 558
Score = 58.2 bits (139), Expect = 1e-07
Identities = 42/156 (26%), Positives = 63/156 (40%), Gaps = 23/156 (14%)
Query: 579 CQGSSSACDPAGTINSNLGY----CQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCH 634
C G S C ++ G C + +G C +CK ++ + + C C C+
Sbjct: 30 CNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR--CLPCNCN 87
Query: 635 KAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGC--------QGCQC 686
G++S + G C CK V G CD C G+ L + GC C C
Sbjct: 88 SKGSLSARCD---NSGRCSCKPGVTGARCDRCLPGFHMLTDA---GCTQDQRLLDSKCDC 141
Query: 687 DIGGALSSMCSGPSGVCQCREHVVGKVCQRPENNYY 722
D G ++ C +G C C+ V G+ C R + YY
Sbjct: 142 DPAG-IAGPCD--AGRCVCKPAVTGERCDRCRSGYY 174
Score = 53.1 bits (126), Expect = 4e-06
Identities = 23/62 (37%), Positives = 32/62 (51%), Gaps = 3/62 (4%)
Query: 1266 CECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCGRRLCEEMTGQ 1325
C+C P G GP C + G+C C+P V G +C RC +G+Y P C + C +
Sbjct: 139 CDCDPAGIAGP-C--DAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSAS 195
Query: 1326 CR 1327
CR
Sbjct: 196 CR 197
Score = 45.8 bits (107), Expect = 7e-04
Identities = 34/130 (26%), Positives = 45/130 (34%), Gaps = 33/130 (25%)
Query: 308 CNINNPEKLF-------RCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCH- 359
CN N+ L RC C+ G CDRC G++ +Q C+C
Sbjct: 84 CNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDP 143
Query: 360 -GHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVD 418
G A C G C+ C+ G C++C GYY G
Sbjct: 144 AGIAGPC--------------------DAGRCV-CKPAVTGERCDRCRSGYYNLDG---G 179
Query: 419 APDGCIPCSC 428
P+GC C C
Sbjct: 180 NPEGCTQCFC 189
Score = 40.8 bits (94), Expect = 0.023
Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 11/72 (15%)
Query: 295 IGGQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTG-YNQRRWRPAAWEQSHEC 353
+ +C C + I P RC C+ GE CDRC +G YN P C
Sbjct: 135 LDSKCDC----DPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEG------C 184
Query: 354 EACNCHGHASNC 365
C C+GH+++C
Sbjct: 185 TQCFCYGHSASC 196
>gi|5453810 netrin 3 [Homo sapiens]
Length = 580
Score = 195 bits (496), Expect = 6e-49
Identities = 132/419 (31%), Positives = 198/419 (47%), Gaps = 48/419 (11%)
Query: 105 CNSEDPRKAH-PVTNAIDG---SERWWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKF 160
C++ DPR+AH P G S W+S L V LT+ LG+ F + ++ ++F
Sbjct: 67 CDASDPRRAHSPALLTSPGGTASPLCWRSESLPRAPL--NVTLTVPLGKAFELVFVSLRF 124
Query: 161 ANSPRPDLWVLERSVDFGSTYSPWQYFAHSKVDCLKEFGR---EANMAVTRDDDVLCVTE 217
++P P L +S D G +++P +F+ C ++GR AN + LC
Sbjct: 125 CSAP-PASVALLKSQDHGRSWAPLGFFSSH---CDLDYGRLPAPANGPAGPGPEALCFPA 180
Query: 218 YSRIVPLENGEVVVSLINGRPGAKNFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKAQ 277
P +G + S+ + P + S L+++ AT++R+ R +T +
Sbjct: 181 -PLAQPDGSGLLAFSMQDSSPPGLDLDSSPVLQDWVTATDVRVVLTRPST------AGDP 233
Query: 278 RDPTVTRRYYYSIKDISIGGQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGY 337
RD Y Y+ D+ +GG+C CNGHA C ++ L C+C+H T G C RC Y
Sbjct: 234 RDMEAVVPYSYAATDLQVGGRCKCNGHASRCLLDTQGHLI-CDCRHGTEGPDCGRCKPFY 292
Query: 338 NQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNT 397
R W+ A +SH C AC+C+GHA C ++ ++ R GGVC+NC+HNT
Sbjct: 293 CDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGR-------RSGGVCLNCRHNT 345
Query: 398 AGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADG--CEQGSGRCHCKPNFHGDNCE 455
AG +C C +G+YR G + C C C P A G C Q +G+C CK G C
Sbjct: 346 AGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCN 405
Query: 456 KCAIGYYNFPFCLRIPIFP-VSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRP 513
+CA G+ R P+ P V TP I G + V P+ CD+H C+P
Sbjct: 406 RCAPGFQQ----SRSPVAPCVKTP---------IPGPTEDSSPVQPQDCDSH----CKP 447
Score = 103 bits (257), Expect = 3e-21
Identities = 67/192 (34%), Positives = 85/192 (44%), Gaps = 41/192 (21%)
Query: 1653 ICACPPAYAGDSCQGCSPGYYRDHKGLYTGR----CVPCNCNGHSNQCQ----------- 1697
IC C G C C P Y T R C+ C+CNGH+ +C+
Sbjct: 273 ICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGR 332
Query: 1698 DGSGICVNCQHNTAGEHCERCQEGYY---GNAV--HGSCRACPCPHTNSFATGCVVNGGD 1752
G+C+NC+HNTAG HC C+EG+Y G A+ +CRAC C A G N
Sbjct: 333 RSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVG--AAGKTCNQTT 390
Query: 1753 VRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKD 1812
+C CK G TG C RCAPG+ Q+ PC P+ G +D
Sbjct: 391 GQCPCKDGVTGLTCNRCAPGF----QQSRSPVAPCVKT---------PIPG-----PTED 432
Query: 1813 SSPAEECDDCDS 1824
SSP + DCDS
Sbjct: 433 SSPVQP-QDCDS 443
Score = 76.3 bits (186), Expect = 5e-13
Identities = 53/163 (32%), Positives = 68/163 (41%), Gaps = 23/163 (14%)
Query: 426 CSCDPEHADGC---EQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSED 482
C C+ HA C QG C C+ G +C +C PF P + S
Sbjct: 255 CKCNG-HASRCLLDTQGHLICDCRHGTEGPDCGRCK------PFYCDRPWQRATARESHA 307
Query: 483 PVA----GDIKGCDCNLEGVLPEICDAHGRCL-CRPGVEGPRCDTCRSGFYSFP------ 531
+A G + C N+E + G CL CR G C CR GFY P
Sbjct: 308 CLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSD 367
Query: 532 --ICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSG 572
C+AC C +G+ C+ TGQC C+ GVTG C+RC G
Sbjct: 368 RRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPG 410
Score = 68.9 bits (167), Expect = 8e-11
Identities = 52/187 (27%), Positives = 74/187 (39%), Gaps = 45/187 (24%)
Query: 356 CNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYY-RPYG 414
C C+GHAS C D G + +C+H T G +C +C Y RP+
Sbjct: 255 CKCNGHASRCLLDTQ----------------GHLICDCRHGTEGPDCGRCKPFYCDRPWQ 298
Query: 415 -VPVDAPDGCIPCSCDPEHADGCE-----------QGSGRC-HCKPNFHGDNCEKCAIGY 461
C+ CSC+ HA C + G C +C+ N G +C C G+
Sbjct: 299 RATARESHACLACSCNG-HARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGF 357
Query: 462 YNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICD-AHGRCLCRPGVEGPRC 520
Y P + D A + CDC+ G + C+ G+C C+ GV G C
Sbjct: 358 YRDP-----------GRALSDRRA--CRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTC 404
Query: 521 DTCRSGF 527
+ C GF
Sbjct: 405 NRCAPGF 411
Score = 66.2 bits (160), Expect = 5e-10
Identities = 55/198 (27%), Positives = 77/198 (38%), Gaps = 30/198 (15%)
Query: 1648 ALAVEICACPPAYAGD--SCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQC---QDGSGI 1702
A V + P+ AGD + P Y GRC CNGH+++C G I
Sbjct: 217 ATDVRVVLTRPSTAGDPRDMEAVVPYSYAATDLQVGGRC---KCNGHASRCLLDTQGHLI 273
Query: 1703 CVNCQHNTAGEHCERCQEGY----YGNAVHGSCRACPCPHTNSFATGCVVN--------- 1749
C +C+H T G C RC+ Y + A AC N A C N
Sbjct: 274 C-DCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGR 332
Query: 1750 -GGDVRCSCKAGYTGTQCERCAPGYFGNPQKF---GGSCQPCSCNSNGQLG-SCHPLTGD 1804
G V +C+ G C C G++ +P + +C+ C C+ G G +C+ TG
Sbjct: 333 RSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQ 392
Query: 1805 CINQEPKDSSPAEECDDC 1822
C KD C+ C
Sbjct: 393 C---PCKDGVTGLTCNRC 407
Score = 66.2 bits (160), Expect = 5e-10
Identities = 45/159 (28%), Positives = 64/159 (40%), Gaps = 30/159 (18%)
Query: 579 CQGSSSAC--DPAGTINSNLGYCQCKLHVEGPTCSRCKLLY----WNLDKENPS-GCSEC 631
C G +S C D G + C C+ EGP C RCK Y W S C C
Sbjct: 257 CNGHASRCLLDTQGHL-----ICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLAC 311
Query: 632 KCH----------KAGTVSGTGECRQGDGDC-HCKSHVGGDSCDTCEDGYF---ALEKSN 677
C+ + +SG R+ G C +C+ + G C C +G++ S+
Sbjct: 312 SCNGHARRCRFNMELYRLSG----RRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSD 367
Query: 678 YFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQR 716
C+ C C GA C+ +G C C++ V G C R
Sbjct: 368 RRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNR 406
Score = 63.2 bits (152), Expect = 4e-09
Identities = 51/176 (28%), Positives = 66/176 (37%), Gaps = 33/176 (18%)
Query: 1282 GGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCGRRLCEEMTGQCRCPPRTVRP--QCEV 1339
GG+C C N +C GH C C G+C+ P RP +
Sbjct: 252 GGRCKC--NGHASRCLLDTQGHL------ICDCRHGTEGPDCGRCK-PFYCDRPWQRATA 302
Query: 1340 CETHSFSFHPMAGCEGCNCSR-----RGTIEAAMPECDRDSGQC-RCKPRITGRQCDRCA 1393
E+H+ C C+C+ R +E R G C C+ GR C C
Sbjct: 303 RESHA--------CLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCR 354
Query: 1394 SGFYRFP--------ECVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCREG 1441
GFYR P C C+C+ G C+ TG C CK+ V G CN C G
Sbjct: 355 EGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPG 410
Score = 55.5 bits (132), Expect = 9e-07
Identities = 54/186 (29%), Positives = 66/186 (35%), Gaps = 32/186 (17%)
Query: 1240 DPQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRC 1299
D Q R N S +G L C+C G GP C C+P R R
Sbjct: 248 DLQVGGRCKCNGHASRCLLDTQGHLICDCRH-GTEGPDCGR------CKPFYCDRPWQR- 299
Query: 1300 ATGHYGFPRCKPCSCG--RRLCE-----------EMTGQC-RCPPRTVRPQCEVCETHSF 1345
AT C CSC R C G C C T C C +
Sbjct: 300 ATARESHA-CLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFY 358
Query: 1346 -----SFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFP 1400
+ C C+C G AA C++ +GQC CK +TG C+RCA GF +
Sbjct: 359 RDPGRALSDRRACRACDCHPVG---AAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQSR 415
Query: 1401 ECV-PC 1405
V PC
Sbjct: 416 SPVAPC 421
Score = 54.7 bits (130), Expect = 2e-06
Identities = 51/218 (23%), Positives = 70/218 (32%), Gaps = 64/218 (29%)
Query: 472 IFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFP 531
+ P S +++ V G K C+ + L + H C CR G EGP C C+ + P
Sbjct: 239 VVPYSYAATDLQVGGRCK-CNGHASRCLLDT-QGHLICDCRHGTEGPDCGRCKPFYCDRP 296
Query: 532 ----------ICQACWCSA--------LGSYQMPCSSVTGQC-ECRPGVTGQRCDRCLSG 572
C AC C+ + Y++ G C CR G+ C C G
Sbjct: 297 WQRATARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREG 356
Query: 573 AYDFPHCQGSSSACDPAGTINSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECK 632
Y DP ++ C C
Sbjct: 357 FYR-----------DPGRALSDR------------------------------RACRACD 375
Query: 633 CHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGY 670
CH G T C Q G C CK V G +C+ C G+
Sbjct: 376 CHPVGAAGKT--CNQTTGQCPCKDGVTGLTCNRCAPGF 411
Score = 41.2 bits (95), Expect = 0.017
Identities = 31/113 (27%), Positives = 42/113 (37%), Gaps = 36/113 (31%)
Query: 1378 CRCKPRITGRQCDRCASGFYRFP----------ECVPCNCNR--------------DGTE 1413
C C+ G C RC + P C+ C+CN G
Sbjct: 274 CDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRR 333
Query: 1414 PGVCDPGTGACL-CKENVEGTECNVCREGSFHLDP----ANLKGCTSCFCFGV 1461
G G CL C+ N G C+ CREG F+ DP ++ + C +C C V
Sbjct: 334 SG------GVCLNCRHNTAGRHCHYCREG-FYRDPGRALSDRRACRACDCHPV 379
>gi|164414431 netrin G1 isoform 1 [Homo sapiens]
Length = 539
Score = 176 bits (446), Expect = 3e-43
Identities = 138/495 (27%), Positives = 204/495 (41%), Gaps = 99/495 (20%)
Query: 65 TCGERGPGEGRPQPELYCKLVGGPTAPGSGHTIQGQFCDYCNSEDPRKAHPVTNAIDGSE 124
TCG+ PE +C A G+ + + C++ P AHP D
Sbjct: 71 TCGD--------PPETFC-------AMGNPYMCNNE----CDASTPELAHPPELMFDFEG 111
Query: 125 R----WWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVDFGST 180
R +WQS + +VN+TL + + ++ S RPD +LE+S+D+G T
Sbjct: 112 RHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRT 171
Query: 181 YSPWQYFAHSKVDCLKEFGREANMAVTRDD----DVLCVTEYSRIVPLENGEVVVSLING 236
+ P+QY+A DCL F + +++C EYS N +++ I
Sbjct: 172 WQPYQYYA---TDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTT-NSKIIHFEIKD 227
Query: 237 R------PGAKNFTFSH-------TLREFTKATNIRLRFLRTNTLLGHLISKAQRDPTVT 283
R P +N + LR+F T++R+R LR + + D
Sbjct: 228 RFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLRP------AVGEIFVDELHL 281
Query: 284 RRYYYSIKDISIGGQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWR 343
RY+Y+I DI + G+C CN HA VC +N + CEC+H+T G C +C Y R W
Sbjct: 282 ARYFYAISDIKVRGRCKCNLHATVCVYDNSK--LTCECEHNTTGPDCGKCKKNYQGRPWS 339
Query: 344 PAAWEQSHECEA------------CNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCI 391
P ++ + A C C GH++ C Y LNT +C+
Sbjct: 340 PGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSYID-------LLNTV-------ICV 385
Query: 392 NCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHA--DGCEQGSGRCHCKPNF 449
+C+HNT G +CE C GY+R +D + CI C C+P + D C GSG C CK
Sbjct: 386 SCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRC-NGSGFCECKTGT 444
Query: 450 HGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRC 509
G C++C G C P D + C G C + RC
Sbjct: 445 TGPKCDECLPGNSWHYGC--------------QPNVCDNELLHCQNGGT----CHNNVRC 486
Query: 510 LCRPGVEGPRCDTCR 524
LC G C+ R
Sbjct: 487 LCPAAYTGILCEKLR 501
Score = 91.7 bits (226), Expect = 1e-17
Identities = 61/177 (34%), Positives = 75/177 (42%), Gaps = 41/177 (23%)
Query: 1654 CACPPAYAGDSCQGC---------SPGYYRDHKGLYTGRCVP-------CNCNGHSNQCQ 1697
C C G C C SPG Y C+P C C GHSN+C
Sbjct: 315 CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCS 374
Query: 1698 D----GSGICVNCQHNTAGEHCERCQEGYYGNAV-----HGSCRACPCPHTNSFATGCVV 1748
+ ICV+C+HNT G+HCE C+ GY+ NA C C C S C
Sbjct: 375 YIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRC-- 432
Query: 1749 NGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNS------NGQLGSCH 1799
G C CK G TG +C+ C P GN +G CQP C++ NG G+CH
Sbjct: 433 -NGSGFCECKTGTTGPKCDECLP---GNSWHYG--CQPNVCDNELLHCQNG--GTCH 481
Score = 79.7 bits (195), Expect = 4e-14
Identities = 69/262 (26%), Positives = 96/262 (36%), Gaps = 65/262 (24%)
Query: 356 CNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYY-RPYG 414
C C+ HA+ C YD + C+HNT G +C +C K Y RP+
Sbjct: 297 CKCNLHATVCVYD-----------------NSKLTCECEHNTTGPDCGKCKKNYQGRPWS 339
Query: 415 ------VPVDAPDGCIPCSCDPEHADGCEQGSGRCH------------CKPNFHGDNCEK 456
+P + CIP + + C S RC CK N G +CE
Sbjct: 340 PGSYLPIPKGTANTCIPSISSIGNCE-CFGHSNRCSYIDLLNTVICVSCKHNTRGQHCEL 398
Query: 457 CAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVE 516
C +GY+ S ++ V + C CN G + + C+ G C C+ G
Sbjct: 399 CRLGYFR----------NASAQLDDENVCIE---CYCNPLGSIHDRCNGSGFCECKTGTT 445
Query: 517 GPRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCL-SGAYD 575
GP+CD C G CQ C C+ G T RCL AY
Sbjct: 446 GPKCDECLPGNSWHYGCQPNVCD------------NELLHCQNGGTCHNNVRCLCPAAYT 493
Query: 576 FPHCQGSSSACDPAGTINSNLG 597
C+ C+ AG+ S+ G
Sbjct: 494 GILCE--KLRCEEAGSCGSDSG 513
Score = 70.5 bits (171), Expect = 3e-11
Identities = 58/202 (28%), Positives = 79/202 (39%), Gaps = 35/202 (17%)
Query: 491 CDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSS 550
C CNL + ++ C C GP C C+ + P W GSY +P
Sbjct: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRP-----WSP--GSY-LPIPK 348
Query: 551 VTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQCKLHVEGPTC 610
T C P ++ C C G S+ C +N+ + CK + G C
Sbjct: 349 GTANT-CIPSISS--IGNC--------ECFGHSNRCSYIDLLNTVI-CVSCKHNTRGQHC 396
Query: 611 SRCKLLYWN-----LDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDT 665
C+L Y+ LD EN C EC C+ G++ C G G C CK+ G CD
Sbjct: 397 ELCRLGYFRNASAQLDDENV--CIECYCNPLGSIHD--RCN-GSGFCECKTGTTGPKCDE 451
Query: 666 CEDGYFALEKSNYFGCQGCQCD 687
C G S ++GCQ CD
Sbjct: 452 CLPG-----NSWHYGCQPNVCD 468
Score = 63.9 bits (154), Expect = 2e-09
Identities = 49/159 (30%), Positives = 59/159 (37%), Gaps = 26/159 (16%)
Query: 1687 CNCNGHSNQC-QDGSGICVNCQHNTAGEHCERCQEGYYGNA-VHGSCRACP------CPH 1738
C CN H+ C D S + C+HNT G C +C++ Y G GS P C
Sbjct: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIP 356
Query: 1739 TNSFATGCVVNGGDVRC------------SCKAGYTGTQCERCAPGYFGNPQ---KFGGS 1783
+ S C G RC SCK G CE C GYF N
Sbjct: 357 SISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENV 416
Query: 1784 CQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 1822
C C CN LGS H E K + +CD+C
Sbjct: 417 CIECYCN---PLGSIHDRCNGSGFCECKTGTTGPKCDEC 452
Score = 51.2 bits (121), Expect = 2e-05
Identities = 53/195 (27%), Positives = 68/195 (34%), Gaps = 47/195 (24%)
Query: 1248 CKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFP 1307
CK + + V Y L CEC TGP C C+ N GR + + P
Sbjct: 297 CKCNLHATVCVYDNSKLTCECE-HNTTGPDCG------KCKKNYQGRPWS--PGSYLPIP 347
Query: 1308 R-----CKP--CSCGRRLCEEMTGQC------------RCPPRTVRPQCEVCETHSF--- 1345
+ C P S G C + +C C T CE+C F
Sbjct: 348 KGTANTCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNA 407
Query: 1346 --SFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPECV 1403
C C C+ G+I C+ SG C CK TG +CD EC+
Sbjct: 408 SAQLDDENVCIECYCNPLGSIH---DRCN-GSGFCECKTGTTGPKCD----------ECL 453
Query: 1404 PCNCNRDGTEPGVCD 1418
P N G +P VCD
Sbjct: 454 PGNSWHYGCQPNVCD 468
Score = 50.1 bits (118), Expect = 4e-05
Identities = 41/165 (24%), Positives = 62/165 (37%), Gaps = 34/165 (20%)
Query: 1308 RCKPCSCGRRLC--EEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIE 1365
RCK C+ +C + C C T P C C+ + + P + + GT
Sbjct: 296 RCK-CNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKN-YQGRPWSPGSYLPIPK-GTAN 352
Query: 1366 AAMP--------ECDRDSGQCR------------CKPRITGRQCDRCASGFYRFPE---- 1401
+P EC S +C CK G+ C+ C G++R
Sbjct: 353 TCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLD 412
Query: 1402 ----CVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCREGS 1442
C+ C CN G+ C+ G+G C CK G +C+ C G+
Sbjct: 413 DENVCIECYCNPLGSIHDRCN-GSGFCECKTGTTGPKCDECLPGN 456
Score = 42.7 bits (99), Expect = 0.006
Identities = 36/147 (24%), Positives = 53/147 (36%), Gaps = 42/147 (28%)
Query: 1356 CNCSRRGTIEAAMPECDRDSGQ--CRCKPRITGRQCDRCASGFYRFP------------- 1400
C C+ T+ C D+ + C C+ TG C +C + P
Sbjct: 297 CKCNLHATV------CVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGT 350
Query: 1401 --ECVP-------CNCNRDGTEPGVCDP-GTGACL-CKENVEGTECNVCREGSF-----H 1444
C+P C C D T C+ CK N G C +CR G F
Sbjct: 351 ANTCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQ 410
Query: 1445 LDPANLKGCTSCFC---FGVNNQCHSS 1468
LD N+ C C+C ++++C+ S
Sbjct: 411 LDDENV--CIECYCNPLGSIHDRCNGS 435
Score = 42.7 bits (99), Expect = 0.006
Identities = 34/118 (28%), Positives = 43/118 (36%), Gaps = 25/118 (21%)
Query: 1264 LPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATG---HYGFPRCKPCSCGRRLCE 1320
+ C C+P G+ C+ G C C+ G +C C G HYG C+P C L
Sbjct: 418 IECYCNPLGSIHDRCNGSGF-CECKTGTTGPKCDECLPGNSWHYG---CQPNVCDNELLH 473
Query: 1321 -EMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQ 1377
+ G C VR C T CE C G+ C DSGQ
Sbjct: 474 CQNGGTCH---NNVRCLCPAAYTGIL-------CEKLRCEEAGS-------CGSDSGQ 514
>gi|190014607 netrin G2 [Homo sapiens]
Length = 530
Score = 169 bits (427), Expect = 6e-41
Identities = 125/454 (27%), Positives = 193/454 (42%), Gaps = 78/454 (17%)
Query: 105 CNSEDPRKAHPVTNAIDGSER----WWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKF 160
C++ +P AHP D E +WQS S N+TL + + ++
Sbjct: 81 CDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPLEANITLSWNKTVELTDDVVMT 140
Query: 161 ANSPRPDLWVLERSVDFGSTYSPWQYFAHSKVDCLKEFGREA----NMAVTRDDDVLCVT 216
RP + VLE+S+D G T+ P+Q++A DC++ FG A +M+ + VLC
Sbjct: 141 FEYGRPTVMVLEKSLDNGRTWQPYQFYAE---DCMEAFGMSARRARDMSSSSAHRVLCTE 197
Query: 217 EYSRIVPLENGEVVVSLINGR------PGAKNFTFSHT-------LREFTKATNIRLRFL 263
EYSR + + V + R P +N +T L+EF T++R+R L
Sbjct: 198 EYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLESAKGLKEFFTLTDLRMRLL 257
Query: 264 RTNTLLGHLISKAQRDPTVTRRYYYSIKDISIGGQCVCNGHAEVCNINNPEKLFRCECQH 323
R L G + + +Y+Y+I +I + G+C CN HA +C++ E +CEC+H
Sbjct: 258 RP-ALGGTYVQREN-----LYKYFYAISNIEVIGRCKCNLHANLCSMR--EGSLQCECEH 309
Query: 324 HTCGETCDRCCTGYNQRRWR-----------PAAWEQSHECEACNCHGHASNCYYDPDVE 372
+T G C +C + R WR P A + C C+GH++ C Y
Sbjct: 310 NTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSYID--- 366
Query: 373 RQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEH 432
+ C++C+HNT G +C+ C GYYR +D + CI C+C+
Sbjct: 367 -----------FLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIG 415
Query: 433 A--DGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKG 490
+ D C + +G C C+ G C+ C +Y C P D
Sbjct: 416 SVHDRCNE-TGFCECREGAAGPKCDDCLPTHYWRQGCY--------------PNVCDDDQ 460
Query: 491 CDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCR 524
C G C + RC C G G RC+ R
Sbjct: 461 LLCQNGGT----CLQNQRCACPRGYTGVRCEQPR 490
Score = 79.3 bits (194), Expect = 6e-14
Identities = 64/243 (26%), Positives = 93/243 (38%), Gaps = 71/243 (29%)
Query: 356 CNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAK-------- 407
C C+ HA+ C ++ SL + C+HNT G +C +C K
Sbjct: 287 CKCNLHANLC------SMREGSLQCE-----------CEHNTTGPDCGKCKKNFRTRSWR 329
Query: 408 -GYYRPYGVPVDAPDGCIPC----SCDPEHADGCEQGSGRCH------------CKPNFH 450
G Y P +P +P+ C +C+ C S RC CK N
Sbjct: 330 AGSYLP--LPHGSPNACATAGSFGNCE------CYGHSNRCSYIDFLNVVTCVSCKHNTR 381
Query: 451 GDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCL 510
G +C+ C +GYY S+E C+CN G + + C+ G C
Sbjct: 382 GQHCQHCRLGYYR-------------NGSAELDDENVCIECNCNQIGSVHDRCNETGFCE 428
Query: 511 CRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSS-----VTGQCECRPGVTGQR 565
CR G GP+CD C Y Q C+ + Q+ C + +C C G TG R
Sbjct: 429 CREGAAGPKCDDCLPTHY---WRQGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVR 485
Query: 566 CDR 568
C++
Sbjct: 486 CEQ 488
Score = 74.7 bits (182), Expect = 1e-12
Identities = 53/179 (29%), Positives = 71/179 (39%), Gaps = 26/179 (14%)
Query: 1687 CNCNGHSNQCQ--DGSGI--CVNCQHNTAGEHCERCQEGYYGNAV-----HGSCRACPCP 1737
C C GHSN+C D + CV+C+HNT G+HC+ C+ GYY N C C C
Sbjct: 353 CECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCN 412
Query: 1738 HTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQP----C----SC 1789
S C G C C+ G G +C+ C P ++ + C C +C
Sbjct: 413 QIGSVHDRCNETG---FCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTC 469
Query: 1790 NSNGQLGSCHPLTGDCINQ---EPKDSSPAEECDDCDSCV---MTLLNDLATMGEQLRL 1842
N + TG Q +P D +CD TLL L +G RL
Sbjct: 470 LQNQRCACPRGYTGVRCEQPRCDPADDDGGLDCDRAPGAAPRPATLLGCLLLLGLAARL 528
Score = 71.2 bits (173), Expect = 2e-11
Identities = 59/207 (28%), Positives = 84/207 (40%), Gaps = 25/207 (12%)
Query: 426 CSCDPEHADGCE--QGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLR--IPIFPVSTPSSE 481
C C+ HA+ C +GS +C C+ N G +C KC + + +P+ P +P++
Sbjct: 287 CKCNL-HANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPL-PHGSPNA- 343
Query: 482 DPVAGDIKGCDCNLEGVLPEICDAHG--RCL-CRPGVEGPRCDTCRSGFY--------SF 530
AG C+C D C+ C+ G C CR G+Y
Sbjct: 344 CATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDE 403
Query: 531 PICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAY----DFPH-CQGSSSA 585
+C C C+ +GS C+ TG CECR G G +CD CL Y +P+ C
Sbjct: 404 NVCIECNCNQIGSVHDRCNE-TGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLL 462
Query: 586 CDPAGTINSNLGYCQCKLHVEGPTCSR 612
C GT N C C G C +
Sbjct: 463 CQNGGTCLQN-QRCACPRGYTGVRCEQ 488
Score = 69.3 bits (168), Expect = 6e-11
Identities = 51/162 (31%), Positives = 67/162 (41%), Gaps = 33/162 (20%)
Query: 1687 CNCNGHSNQC--QDGSGICVNCQHNTAGEHCERCQE---------GYYGNAVHGSCRACP 1735
C CN H+N C ++GS C C+HNT G C +C++ G Y HGS AC
Sbjct: 287 CKCNLHANLCSMREGSLQC-ECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACA 345
Query: 1736 CPHTNSFATGCVVNGGDVRC------------SCKAGYTGTQCERCAPGYFGNPQ---KF 1780
SF C G RC SCK G C+ C GY+ N
Sbjct: 346 T--AGSFG-NCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDD 402
Query: 1781 GGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 1822
C C+CN Q+GS H + E ++ + +CDDC
Sbjct: 403 ENVCIECNCN---QIGSVHDRCNETGFCECREGAAGPKCDDC 441
Score = 66.2 bits (160), Expect = 5e-10
Identities = 59/237 (24%), Positives = 89/237 (37%), Gaps = 44/237 (18%)
Query: 491 CDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSS 550
C CNL L + + +C C GP C C+ F + W + GSY +P
Sbjct: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRT-----RSWRA--GSY-LPL-- 336
Query: 551 VTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQCKLHVEGPTC 610
P + C +G++ C G S+ C +N + CK + G C
Sbjct: 337 --------PHGSPNAC--ATAGSFGNCECYGHSNRCSYIDFLNV-VTCVSCKHNTRGQHC 385
Query: 611 SRCKLLYWN-----LDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDT 665
C+L Y+ LD EN C EC C++ G+V C + G C C+ G CD
Sbjct: 386 QHCRLGYYRNGSAELDDENV--CIECNCNQIGSVHD--RCNE-TGFCECREGAAGPKCDD 440
Query: 666 CEDGYFALEKSNYFGCQGCQCDIGGALSSMCSG-----PSGVCQCREHVVGKVCQRP 717
C ++ QGC ++ +C + C C G C++P
Sbjct: 441 C--------LPTHYWRQGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQP 489
Score = 58.9 bits (141), Expect = 8e-08
Identities = 42/133 (31%), Positives = 55/133 (41%), Gaps = 22/133 (16%)
Query: 1651 VEICACPPAYAGDSCQGCSPGYYRDHKGLYTGR--CVPCNCN--GHSNQCQDGSGICVNC 1706
V +C G CQ C GYYR+ C+ CNCN G + + +G C C
Sbjct: 371 VTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNETGFC-EC 429
Query: 1707 QHNTAGEHCERC------QEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAG 1760
+ AG C+ C ++G Y N C T C+ N RC+C G
Sbjct: 430 REGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGT------CLQN---QRCACPRG 480
Query: 1761 YTGTQCE--RCAP 1771
YTG +CE RC P
Sbjct: 481 YTGVRCEQPRCDP 493
Score = 51.6 bits (122), Expect = 1e-05
Identities = 48/199 (24%), Positives = 69/199 (34%), Gaps = 52/199 (26%)
Query: 1248 CKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFP 1307
CK + + + +G+L CEC TGP C C+ N R A + P
Sbjct: 287 CKCNLHANLCSMREGSLQCECE-HNTTGPDCG------KCKKNFRTRSWR--AGSYLPLP 337
Query: 1308 RCKPCSCGRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAA 1367
P +C G C C + R C + F + C C + R
Sbjct: 338 HGSPNACA---TAGSFGNCECYGHSNR--CSYID-----FLNVVTCVSCKHNTR------ 381
Query: 1368 MPECDRDSGQCRCKPRITGRQCDRCASGFYRFPE--------CVPCNCNRDGTEPGVCDP 1419
G+ C C G+YR C+ CNCN+ G+ C+
Sbjct: 382 ------------------GQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNE 423
Query: 1420 GTGACLCKENVEGTECNVC 1438
TG C C+E G +C+ C
Sbjct: 424 -TGFCECREGAAGPKCDDC 441
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 130 bits (327), Expect = 2e-29
Identities = 129/471 (27%), Positives = 163/471 (34%), Gaps = 123/471 (26%)
Query: 324 HTCGETCDRCCTGYNQRRWR-----PAAWEQSHECEACNCHGHASNCYYDPDVERQQASL 378
H C TCD C G P W E C NC + +
Sbjct: 518 HDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQ------ 571
Query: 379 NTQGIYAGGGVC------INCQHNTAGVNCEQ-CAKGYY-----------------RPYG 414
GG C C +G NCE C KGYY R YG
Sbjct: 572 -------NGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYG 624
Query: 415 VPVDAP-----------------DGCI-PCSCDPEHADGCEQGSGRCHCKPNFHGDNCE- 455
+ P GC C C H C++ G C CK F G+ C+
Sbjct: 625 ACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQA 684
Query: 456 KCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGD--------IKGCDCNLE---GVLPEICD 504
+C +GY+ P C + PV D V+G+ +G DC E G C
Sbjct: 685 ECELGYFG-PGCWQACTCPVGVAC--DSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCS 741
Query: 505 AH------------GRCLCRPGVEGPRCDT-CRSGFYSF---PICQACWCSALGSYQMPC 548
+ G+C C PG G C+ C G + IC AC + C
Sbjct: 742 SSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPAC------QHAARC 795
Query: 549 SSVTGQCECRPGVTGQRC-DRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQCKLHVEG 607
TG C C PG G RC D C +G Y P CQ + +C G + G+C C G
Sbjct: 796 DPETGACLCLPGFVGSRCQDVCPAGWYG-PSCQ-TRCSCANDGHCHPATGHCSCAPGWTG 853
Query: 608 PTCSR-CKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCD-T 665
+C R C +W D +P CS +G G C G C C++ G C+
Sbjct: 854 FSCQRACDTGHWGPDCSHPCNCS----------AGHGSCDAISGLCLCEAGYVGPRCEQQ 903
Query: 666 CEDGYFALEKSNYFGC-QGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQ 715
C G+F GC Q CQC G A C SG C C G C+
Sbjct: 904 CPQGHFGP------GCEQRCQCQHGAA----CDHVSGACTCPAGWRGTFCE 944
Score = 122 bits (306), Expect = 6e-27
Identities = 131/485 (27%), Positives = 167/485 (34%), Gaps = 128/485 (26%)
Query: 294 SIGGQCVCNGH--AEVCNINNPEKLF------RCECQHHTCGETCDRCCTGYNQRRWRPA 345
+I G C+C C P+ F RC+CQH + CT PA
Sbjct: 884 AISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTC-------PA 936
Query: 346 AWEQS---HECEA----CNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTA 398
W + H C A +C A NC + S G C +T
Sbjct: 937 GWRGTFCEHACPAGFFGLDCRS-ACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTY 995
Query: 399 GVNCEQ---CAKGYYRPYGVPVDAPDGCIPCSCDPEHADGCEQGSGRCHCKPNFHGDNC- 454
G NC Q C G SCDP H G+CHC P + G +C
Sbjct: 996 GHNCSQACACFNG-----------------ASCDPVH--------GQCHCAPGWMGPSCL 1030
Query: 455 EKCAIGYYN---FPFCLRIPIFPVSTPSSEDPVAGDI------KGCDCNLEGVLPE---- 501
+ C G Y CL + DPV+G G C E LP
Sbjct: 1031 QACPAGLYGDNCRHSCL------CQNGGTCDPVSGHCACPEGWAGLACEKE-CLPRDVRA 1083
Query: 502 ------------ICDAH-GRCLCRPGVEGPRCDT-CRSGFYSFPICQACWCSALGSYQMP 547
+CD H GRCLC G G +C + C G++ Q C C +
Sbjct: 1084 GCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAA---- 1139
Query: 548 CSSVTGQCECRPGVTGQRCDR-CLSGAY-----DFPHCQGSSSACDPAGTINSNLGYCQC 601
C VTG C C PG TG C++ C G++ C G + AC PA G C C
Sbjct: 1140 CHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPA------TGTCSC 1193
Query: 602 KLHVEGPTC-SRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGG 660
GP+C RC P G C + G C G C C + G
Sbjct: 1194 AAGYHGPSCQQRC-----------PPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLG 1242
Query: 661 DSCD-TCEDGYFALEKSNYFGC-QGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQR-- 716
C+ TC G F ++ GC QG CD +G C C G C+R
Sbjct: 1243 TDCNLTCPQGRFGPNCTHVCGCGQGAACD----------PVTGTCLCPPGRAGVRCERGC 1292
Query: 717 PENNY 721
P+N +
Sbjct: 1293 PQNRF 1297
Score = 111 bits (277), Expect = 1e-23
Identities = 128/472 (27%), Positives = 172/472 (36%), Gaps = 108/472 (22%)
Query: 317 FRCECQHHTCGETCD------RC---CTGYNQRRWRPAAWEQSHECEACNC------HGH 361
F C CQ+ G TCD RC +G N P + H + CNC H
Sbjct: 566 FSCSCQN---GGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRL 622
Query: 362 ASNCYYDPDV--------------------ERQQASLNTQGIYAGGGVCINCQHNTAGVN 401
C DP + E Q +TQ G C +C+ G
Sbjct: 623 YGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSC-SCKAGFRGER 681
Query: 402 CE-QCAKGYYRPYGVPVDAPDGCIP-CSCDPEHADGCEQGSGRC--HCKPNFHGDNC-EK 456
C+ +C GY+ P GC C+C A C+ SG C C F G++C ++
Sbjct: 682 CQAECELGYFGP---------GCWQACTCPVGVA--CDSVSGECGKRCPAGFQGEDCGQE 730
Query: 457 CAIGYYNFPF-----CLRIPIFPVSTPSSEDPV-AGDIKGCDCNLEGV----LPEICDA- 505
C +G + C P V+ P G+ DC EG EIC A
Sbjct: 731 CPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCP-EGRWGLGCQEICPAC 789
Query: 506 ---------HGRCLCRPGVEGPRC-DTCRSGFYSFPICQA-CWCSALGSYQMPCSSVTGQ 554
G CLC PG G RC D C +G+Y P CQ C C+ G C TG
Sbjct: 790 QHAARCDPETGACLCLPGFVGSRCQDVCPAGWYG-PSCQTRCSCANDGH----CHPATGH 844
Query: 555 CECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQCKLHVEGPTC-SRC 613
C C PG TG C R + P C + G+ ++ G C C+ GP C +C
Sbjct: 845 CSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQC 904
Query: 614 KLLYWNLDKENPSGCSE-CKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCD-TCEDGYF 671
++ GC + C+C C G C C + G C+ C G+F
Sbjct: 905 PQGHFG------PGCEQRCQCQHGAA------CDHVSGACTCPAGWRGTFCEHACPAGFF 952
Query: 672 ALEKSNYFGC-QGCQCDIGGALSSMCSGPSG------VCQCREHVVGKVCQR 716
L+ + C G CD A++ C P+G C H G C +
Sbjct: 953 GLDCRSACNCTAGAACD---AVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQ 1001
Score = 101 bits (252), Expect = 1e-20
Identities = 121/496 (24%), Positives = 158/496 (31%), Gaps = 124/496 (25%)
Query: 321 CQHHTCGETCDRCCTGYNQRRWRPA--------AWEQSHECEACNCHGHASNCYYDPDVE 372
C HT G C + C +N P W +AC + NC +
Sbjct: 990 CPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSC--- 1046
Query: 373 RQQASLNTQGIYAGGGVC------INCQHNTAGVNCE-QCAKGYYRPYGVPVDAPDGCIP 425
+ GG C C AG+ CE +C +P D GC
Sbjct: 1047 ----------LCQNGGTCDPVSGHCACPEGWAGLACEKEC---------LPRDVRAGC-- 1085
Query: 426 CSCDPEHADGCEQG------SGRCHCKPNFHGDNCEK-CAIGYYNFPFCLRIPIFPVS-- 476
H+ GC G +GRC C + GD C+ C G++ R P +
Sbjct: 1086 -----RHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAAC 1140
Query: 477 ---TPSSEDPVAGDIKGCD---------------CNLEGVLPEICDAHGRCLCRPGVEGP 518
T + P GC+ C G P A G C C G GP
Sbjct: 1141 HHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGP 1200
Query: 519 RCDT-CRSGFYSFPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCD-RCLSGAYDF 576
C C G Y Q C C GS C + TG C C G G C+ C G +
Sbjct: 1201 SCQQRCPPGRYGPGCEQLCGCLNGGS----CDAATGACRCPTGFLGTDCNLTCPQGRFG- 1255
Query: 577 PHCQ-----GSSSACDPA-----------------GTINSNLGY-----CQCK----LHV 605
P+C G +ACDP G + G C C+ H
Sbjct: 1256 PNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHA 1315
Query: 606 EGPTCSRCKLLYWNLDKEN--PSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSC 663
+CS C L + E P G CH + C G C C G +C
Sbjct: 1316 SNGSCS-CGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQAC 1374
Query: 664 D-TCEDGYFALEKSNYFGCQG-CQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENNY 721
+ C G+ GCQG C C G C SG C C G C+R
Sbjct: 1375 EHPCPPGFHGA------GCQGLCWCQHGAP----CDPISGRCLCPAGFHGHFCERGCEPG 1424
Query: 722 YFPDLHHMKYEIEDGS 737
F + H + + + G+
Sbjct: 1425 SFGEGCHQRCDCDGGA 1440
Score = 98.6 bits (244), Expect = 9e-20
Identities = 68/211 (32%), Positives = 82/211 (38%), Gaps = 27/211 (12%)
Query: 1266 CECHPTGATGPHCSPEGGQCPCQPNVIGRQCTR-CATGHYGFPRCKPCSC--GRRLCEEM 1322
C+ + A HC P G C C P G C R C TGH+G PC+C G C+ +
Sbjct: 826 CQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAI 885
Query: 1323 TGQCRCPPRTVRPQCE-VCETHSFSFHPMAGCE-GCNCSRRGTIEAAMPECDRDSGQCRC 1380
+G C C V P+CE C F GCE C C CD SG C C
Sbjct: 886 SGLCLCEAGYVGPRCEQQCPQGHFG----PGCEQRCQCQHGAA-------CDHVSGACTC 934
Query: 1381 KPRITGRQCDR-CASGFYRFPECVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCR 1439
G C+ C +GF+ CNC T CD G+CLC G C
Sbjct: 935 PAGWRGTFCEHACPAGFFGLDCRSACNC----TAGAACDAVNGSCLCPAGRRGPRC--AE 988
Query: 1440 EGSFHLDPANLKGCTSCF----CFGVNNQCH 1466
H N +CF C V+ QCH
Sbjct: 989 TCPAHTYGHNCSQACACFNGASCDPVHGQCH 1019
Score = 94.4 bits (233), Expect = 2e-18
Identities = 76/213 (35%), Positives = 83/213 (38%), Gaps = 36/213 (16%)
Query: 1266 CECHPTGATGPHCSPEGGQCPCQPNVIGRQCT-RCATGHYGFPRCKPCSC-GRRLCEEMT 1323
C C G C G C C GR C C G YG CSC CE T
Sbjct: 1305 CSCRNGGL----CHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPAT 1360
Query: 1324 GQCRCPPRTVRPQCE-VCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKP 1382
G CRC P CE C FH AGC+G + G CD SG+C C
Sbjct: 1361 GTCRCGPGFYGQACEHPCPP---GFHG-AGCQGLCWCQHGA------PCDPISGRCLCPA 1410
Query: 1383 RITGRQCDR-CASGFYRFPECVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNV-CRE 1440
G C+R C G F E C+ DG P CDP TG CLC G CN+ CR
Sbjct: 1411 GFHGHFCERGCEPG--SFGEGCHQRCDCDGGAP--CDPVTGLCLCPPGRSGATCNLDCRR 1466
Query: 1441 GSFHLDPANLKGCT-SCFCFG------VNNQCH 1466
G F CT C C G V+ QCH
Sbjct: 1467 GQFG------PSCTLHCDCGGGADCDPVSGQCH 1493
Score = 92.4 bits (228), Expect = 7e-18
Identities = 70/247 (28%), Positives = 93/247 (37%), Gaps = 34/247 (13%)
Query: 1228 FITNCGKNSFYLDPQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHC-----SPEG 1282
F C + + P T S ++ + S A + EC G GP C P G
Sbjct: 646 FGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECE-LGYFGPGCWQACTCPVG 704
Query: 1283 GQCPCQPNVIGRQCT----------RCATGHYGFPRCKPCSCGRRLCEEMTGQCRCPPRT 1332
C G++C C G +G CSCG C +TGQCRCPP
Sbjct: 705 VACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGR 764
Query: 1333 VRPQCEV-CETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQC-D 1390
CE C + C C + R CD ++G C C P G +C D
Sbjct: 765 TGEDCEADCPEGRWGLGCQEICPACQHAAR---------CDPETGACLCLPGFVGSRCQD 815
Query: 1391 RCASGFYRFPEC-VPCNCNRDGTEPGVCDPGTGACLCKENVEGTEC-NVCREGSFHLDPA 1448
C +G+Y P C C+C DG C P TG C C G C C G + D +
Sbjct: 816 VCPAGWYG-PSCQTRCSCANDGH----CHPATGHCSCAPGWTGFSCQRACDTGHWGPDCS 870
Query: 1449 NLKGCTS 1455
+ C++
Sbjct: 871 HPCNCSA 877
Score = 91.7 bits (226), Expect = 1e-17
Identities = 115/469 (24%), Positives = 146/469 (31%), Gaps = 124/469 (26%)
Query: 318 RCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECE-ACNCHGHASNCYYDPDVERQQA 376
RC C G+ C C R W A Q C CH C P
Sbjct: 1103 RCLCPAGWTGDKCQSPCL----RGWFGEACAQRCSCPPGAACHHVTGACRCPPG------ 1152
Query: 377 SLNTQGIYAGGGVCINCQHNTAGVNCEQ-------------------CAKGYYRP----- 412
+ G G C + G +C Q CA GY+ P
Sbjct: 1153 -------FTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQR 1205
Query: 413 -----YGVPVDAPDGCIPCSCDPEHADGCEQGSGRCHCKPNFHGDNCE-KCAIGYYNFPF 466
YG + GC+ + C+ +G C C F G +C C G + P
Sbjct: 1206 CPPGRYGPGCEQLCGCL-------NGGSCDAATGACRCPTGFLGTDCNLTCPQGRFG-PN 1257
Query: 467 CLRIPIFPVSTPSSEDPVAGDI------------KGCDCNLEGVLPE---------ICDA 505
C + ++ DPV G +GC N GV E +C A
Sbjct: 1258 CTHV--CGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHA 1315
Query: 506 -HGRCLCRPGVEGPRCD-TCRSGFYSFPICQACWCSALGSYQMPCSSVTGQCECRPGVTG 563
+G C C G G C+ C G Y C C + C TG C C PG G
Sbjct: 1316 SNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNST----CEPATGTCRCGPGFYG 1371
Query: 564 QRCDRCLSGAYDFPHCQG-----SSSACDPAGTINSNLGYCQCKLHVEGPTCSR-CKLLY 617
Q C+ + CQG + CDP G C C G C R C+
Sbjct: 1372 QACEHPCPPGFHGAGCQGLCWCQHGAPCDPIS------GRCLCPAGFHGHFCERGCE--- 1422
Query: 618 WNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCD-TCEDGYFALEKS 676
P E CH+ G C G C C G +C+ C G F +
Sbjct: 1423 -------PGSFGE-GCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCT 1474
Query: 677 NYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQR------PEN 719
CD GG C SG C C + +G C+ PEN
Sbjct: 1475 -------LHCDCGGGAD--CDPVSGQCHCVDGYMGPTCREGGPLRLPEN 1514
Score = 90.1 bits (222), Expect = 3e-17
Identities = 66/207 (31%), Positives = 84/207 (40%), Gaps = 23/207 (11%)
Query: 1268 CHPTGA--TGPHCSPEGGQCPCQPNVIGRQC-TRCATGHYGFPRCKPCSCGR-RLCEEMT 1323
C +G G C P G+C C G +C + C G +G + CSC C +T
Sbjct: 1085 CRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVT 1144
Query: 1324 GQCRCPPRTVRPQCE-VCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKP 1382
G CRCPP CE C SF G +C++ P C +G C C
Sbjct: 1145 GACRCPPGFTGSGCEQACPPGSF---------GEDCAQMCQCPGENPACHPATGTCSCAA 1195
Query: 1383 RITGRQCD-RCASGFYRFPECVP-CNCNRDGTEPGVCDPGTGACLCKENVEGTECNV-CR 1439
G C RC G Y P C C C G+ CD TGAC C GT+CN+ C
Sbjct: 1196 GYHGPSCQQRCPPGRYG-PGCEQLCGCLNGGS----CDAATGACRCPTGFLGTDCNLTCP 1250
Query: 1440 EGSFHLDPANLKGC-TSCFCFGVNNQC 1465
+G F + ++ GC C V C
Sbjct: 1251 QGRFGPNCTHVCGCGQGAACDPVTGTC 1277
Score = 85.5 bits (210), Expect = 8e-16
Identities = 74/272 (27%), Positives = 99/272 (36%), Gaps = 31/272 (11%)
Query: 1260 HKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTR-CATGHYGFPRCKPCSC-GRR 1317
H + C C G C P GQC C P +G C + C G YG C C
Sbjct: 997 HNCSQACACF----NGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGG 1052
Query: 1318 LCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQ 1377
C+ ++G C CP CE AGC G + CD +G+
Sbjct: 1053 TCDPVSGHCACPEGWAG---LACEKECLPRDVRAGCRHSGGCLNGGL------CDPHTGR 1103
Query: 1378 CRCKPRITGRQCDR-CASGFYRFPECVPCNCNRDGTEPG-VCDPGTGACLCKENVEGTEC 1435
C C TG +C C G++ C+C PG C TGAC C G+ C
Sbjct: 1104 CLCPAGWTGDKCQSPCLRGWFGEACAQRCSC-----PPGAACHHVTGACRCPPGFTGSGC 1158
Query: 1436 -NVCREGSFHLDPANLKGCTSCFCFGVNNQCHSSHKRRTKFVDMLGWHLETADRVDIPVS 1494
C GSF D A + C C G N CH + + G+H + + P
Sbjct: 1159 EQACPPGSFGEDCAQM-----CQCPGENPACHPATGTCS---CAAGYHGPSCQQRCPPGR 1210
Query: 1495 FNPGSNSMVADLQELPATIHSASWVAPTSYLG 1526
+ PG + L + + PT +LG
Sbjct: 1211 YGPGCEQLCGCLNGGSCDAATGACRCPTGFLG 1242
Score = 84.0 bits (206), Expect = 2e-15
Identities = 64/210 (30%), Positives = 83/210 (39%), Gaps = 29/210 (13%)
Query: 1266 CECHPTGATGPHCSPEGGQCPCQPNVIGRQCTR-CATGHYGFPRCKPCSCGRR-LCEEMT 1323
C C G C G C C P V G C C G+YG K C+C R C +
Sbjct: 568 CSCQNGGT----CDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLY 623
Query: 1324 GQCRCPPRTVRPQCEV-CETHSFSFHPMAGC-EGCNCSRRGTIEAAMPECDRDSGQCRCK 1381
G C C P C + C +F GC E C C ++ CD+ G C CK
Sbjct: 624 GACLCDPGLYGRFCHLTCPPWAFG----PGCSEECQC-----VQPHTQSCDKRDGSCSCK 674
Query: 1382 PRITGRQCD-RCASGFYRFPEC-VPCNCNRDGTEPGV-CDPGTGAC--LCKENVEGTECN 1436
G +C C G++ P C C C GV CD +G C C +G +C
Sbjct: 675 AGFRGERCQAECELGYFG-PGCWQACTC-----PVGVACDSVSGECGKRCPAGFQGEDCG 728
Query: 1437 V-CREGSFHLDPANLKGCTSCFCFGVNNQC 1465
C G+F ++ ++ C C GV QC
Sbjct: 729 QECPVGTFGVNCSSSCSCGGAPCHGVTGQC 758
Score = 80.9 bits (198), Expect = 2e-14
Identities = 70/241 (29%), Positives = 91/241 (37%), Gaps = 44/241 (18%)
Query: 1232 CGKNSFYLDPQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNV 1291
C +SF D C+N L+ G C+C P G TG C+ C P+
Sbjct: 511 CLDDSFGHDCSLTCDDCRNGGTCLL-----GLDGCDC-PEGWTGLICNET-----CPPDT 559
Query: 1292 IGRQCTRCATGHYGFPRCKPCSCGRR-LCEEMTGQCRCPPRTVRPQCE-VCETHSFSFHP 1349
G+ C+ CSC C+ +TG CRCPP CE C + H
Sbjct: 560 FGKNCSFS------------CSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHC 607
Query: 1350 MAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPEC-VPCNCN 1408
+ CNC+ RG C R G C C P + GR C + P C C C
Sbjct: 608 R---KKCNCANRG-------RCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCV 657
Query: 1409 RDGTEPGVCDPGTGACLCKENVEGTECNV-CREGSFHLDPANLKGCT---SCFCFGVNNQ 1464
+ T+ CD G+C CK G C C G F P + CT C V+ +
Sbjct: 658 QPHTQS--CDKRDGSCSCKAGFRGERCQAECELGYF--GPGCWQACTCPVGVACDSVSGE 713
Query: 1465 C 1465
C
Sbjct: 714 C 714
Score = 75.5 bits (184), Expect = 8e-13
Identities = 61/211 (28%), Positives = 75/211 (35%), Gaps = 34/211 (16%)
Query: 1266 CECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGH-YGFPRCKPCSC-GRRLCEEMT 1323
C C G C G C C G +C H YG + C+C C+ +
Sbjct: 960 CNC----TAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVH 1015
Query: 1324 GQCRCPPRTVRPQC-EVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKP 1382
GQC C P + P C + C AG G NC R + CD SG C C
Sbjct: 1016 GQCHCAPGWMGPSCLQACP---------AGLYGDNC-RHSCLCQNGGTCDPVSGHCACPE 1065
Query: 1383 RITGRQCDRCASGFYRFPECVP----CNCNRDG--TEPGVCDPGTGACLCKENVEGTEC- 1435
G C++ EC+P C G G+CDP TG CLC G +C
Sbjct: 1066 GWAGLACEK---------ECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQ 1116
Query: 1436 NVCREGSFHLDPANLKGC-TSCFCFGVNNQC 1465
+ C G F A C C V C
Sbjct: 1117 SPCLRGWFGEACAQRCSCPPGAACHHVTGAC 1147
Score = 74.7 bits (182), Expect = 1e-12
Identities = 47/156 (30%), Positives = 69/156 (44%), Gaps = 27/156 (17%)
Query: 1654 CACPPAYAGDSCQ-GCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAG 1712
C+C P + G SCQ C G++ PCNC+ C SG+C+ C+ G
Sbjct: 845 CSCAPGWTGFSCQRACDTGHWGPDCSH------PCNCSAGHGSCDAISGLCL-CEAGYVG 897
Query: 1713 EHCER-CQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAP 1771
CE+ C +G++G G + C C H G + C+C AG+ GT CE P
Sbjct: 898 PRCEQQCPQGHFGP---GCEQRCQCQH------GAACDHVSGACTCPAGWRGTFCEHACP 948
Query: 1772 GYFGNPQKFGGSCQ-PCSCNSNGQLGSCHPLTGDCI 1806
F FG C+ C+C + +C + G C+
Sbjct: 949 AGF-----FGLDCRSACNCTAG---AACDAVNGSCL 976
Score = 73.9 bits (180), Expect = 2e-12
Identities = 50/164 (30%), Positives = 67/164 (40%), Gaps = 28/164 (17%)
Query: 1645 GRIALAVEICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVP-CNCNGHSNQCQDGSGIC 1703
G A C CP + G C P +G + C C C G C +G C
Sbjct: 1225 GSCDAATGACRCPTGFLGTDCNLTCP------QGRFGPNCTHVCGC-GQGAACDPVTGTC 1277
Query: 1704 VNCQHNTAGEHCER-CQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYT 1762
+ C AG CER C + +G C HT S G + + + CSC G+T
Sbjct: 1278 L-CPPGRAGVRCERGCPQNRFGVG---------CEHTCSCRNGGLCHASNGSCSCGLGWT 1327
Query: 1763 GTQCERCAPGYFGNPQKFGGSCQ-PCSCNSNGQLGSCHPLTGDC 1805
G CE P P ++G +C CSC++N +C P TG C
Sbjct: 1328 GRHCELACP-----PGRYGAACHLECSCHNN---STCEPATGTC 1363
Score = 72.8 bits (177), Expect = 5e-12
Identities = 59/183 (32%), Positives = 76/183 (41%), Gaps = 27/183 (14%)
Query: 1264 LPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTR-CATGHYGFPRCKPCSCGRRL-CEE 1321
L C CH C P G C C P G+ C C G +G C C C+
Sbjct: 1346 LECSCHNNST----CEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDP 1401
Query: 1322 MTGQCRCPPRTVRPQCEV-CETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRC 1380
++G+C CP CE CE SF EGC+ +R + P CD +G C C
Sbjct: 1402 ISGRCLCPAGFHGHFCERGCEPGSFG-------EGCH--QRCDCDGGAP-CDPVTGLCLC 1451
Query: 1381 KPRITGRQCDR-CASGFYRFPEC-VPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVC 1438
P +G C+ C G + P C + C+C CDP +G C C V+G C
Sbjct: 1452 PPGRSGATCNLDCRRGQFG-PSCTLHCDCGGGAD----CDPVSGQCHC---VDGYMGPTC 1503
Query: 1439 REG 1441
REG
Sbjct: 1504 REG 1506
Score = 72.0 bits (175), Expect = 9e-12
Identities = 50/162 (30%), Positives = 64/162 (39%), Gaps = 39/162 (24%)
Query: 1654 CACPPAYAGDSC-QGCSPGYYRDHKGLYTGRCVP-CNCNGHSNQCQDGSGICVNCQHNTA 1711
C CPP + G C Q C PG + + C C C G + C +G C +C
Sbjct: 1147 CRCPPGFTGSGCEQACPPGSFGED-------CAQMCQCPGENPACHPATGTC-SCAAGYH 1198
Query: 1712 GEHCE-RCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDV-----RCSCKAGYTGTQ 1765
G C+ RC G YG C GC+ NGG C C G+ GT
Sbjct: 1199 GPSCQQRCPPGRYGPGCEQLC-------------GCL-NGGSCDAATGACRCPTGFLGTD 1244
Query: 1766 CERCAPGYFGNPQKFGGSC-QPCSCNSNGQLGSCHPLTGDCI 1806
C P +FG +C C C GQ +C P+TG C+
Sbjct: 1245 CNLTCP-----QGRFGPNCTHVCGC---GQGAACDPVTGTCL 1278
Score = 71.2 bits (173), Expect = 2e-11
Identities = 51/156 (32%), Positives = 68/156 (43%), Gaps = 28/156 (17%)
Query: 1654 CACPPAYAGDSCQ-GCSPGYYRDHKGLYTGRC-VPCNCNGHSNQCQDGSGICVNCQHNTA 1711
C CPP +G +C+ GC GYY H C CNC + +C G C+ C
Sbjct: 583 CRCPPGVSGTNCEDGCPKGYYGKH-------CRKKCNC-ANRGRCHRLYGACL-CDPGLY 633
Query: 1712 GEHCE-RCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCE-RC 1769
G C C +G C+ C PHT S + D CSCKAG+ G +C+ C
Sbjct: 634 GRFCHLTCPPWAFGPGCSEECQ-CVQPHTQS------CDKRDGSCSCKAGFRGERCQAEC 686
Query: 1770 APGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDC 1805
GYFG G Q C+C +C ++G+C
Sbjct: 687 ELGYFG-----PGCWQACTCPVG---VACDSVSGEC 714
Score = 69.3 bits (168), Expect = 6e-11
Identities = 55/178 (30%), Positives = 72/178 (40%), Gaps = 31/178 (17%)
Query: 1634 VGLEEASDTGSGRIALAVE-ICACPPAYAGDSCQ-GCSPGYYRDHKGLYTGRCVPCNCNG 1691
VG E +G + A C+C + G C+ C PG Y G C+
Sbjct: 1299 VGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRY--------GAACHLECSC 1350
Query: 1692 HSNQ-CQDGSGICVNCQHNTAGEHCER-CQEGYYGNAVHGSCRACPCPHTNSFATGCVVN 1749
H+N C+ +G C C G+ CE C G++G G C C H G +
Sbjct: 1351 HNNSTCEPATGTC-RCGPGFYGQACEHPCPPGFHGAGCQGLCW---CQH------GAPCD 1400
Query: 1750 GGDVRCSCKAGYTGTQCER-CAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCI 1806
RC C AG+ G CER C PG FG G Q C C+ C P+TG C+
Sbjct: 1401 PISGRCLCPAGFHGHFCERGCEPGSFGE-----GCHQRCDCDGG---APCDPVTGLCL 1450
Score = 68.9 bits (167), Expect = 8e-11
Identities = 52/158 (32%), Positives = 65/158 (41%), Gaps = 34/158 (21%)
Query: 1654 CACPPAYAGDSC-QGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAG 1712
C C P + G SC Q C G Y D NC HS CQ+G G C +
Sbjct: 1018 CHCAPGWMGPSCLQACPAGLYGD------------NCR-HSCLCQNG-GTC-----DPVS 1058
Query: 1713 EHCERCQEGYYGNAVHGSCRA----CPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCER 1768
HC C EG+ G A C C H+ G + + RC C AG+TG +C+
Sbjct: 1059 GHCA-CPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQS 1117
Query: 1769 -CAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDC 1805
C G+FG Q CSC +CH +TG C
Sbjct: 1118 PCLRGWFGE-----ACAQRCSCPPG---AACHHVTGAC 1147
Score = 64.7 bits (156), Expect = 1e-09
Identities = 54/159 (33%), Positives = 66/159 (41%), Gaps = 35/159 (22%)
Query: 1654 CACPPAYAGDSCQG-CSPGYYRDHKGLYTGRCVP-CNCNGHSNQCQDGSGICVNCQHNTA 1711
C CP + GD CQ C G++ + C C+C + C +G C C
Sbjct: 1104 CLCPAGWTGDKCQSPCLRGWFGE-------ACAQRCSCPPGA-ACHHVTGAC-RCPPGFT 1154
Query: 1712 GEHCER-CQEGYYGNAVHGSCRACPCPHTNSF---ATGCVVNGGDVRCSCKAGYTGTQC- 1766
G CE+ C G +G + C CP N ATG CSC AGY G C
Sbjct: 1155 GSGCEQACPPGSFGE---DCAQMCQCPGENPACHPATGT--------CSCAAGYHGPSCQ 1203
Query: 1767 ERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDC 1805
+RC PG +G G Q C C NG GSC TG C
Sbjct: 1204 QRCPPGRYG-----PGCEQLCGC-LNG--GSCDAATGAC 1234
Score = 64.3 bits (155), Expect = 2e-09
Identities = 45/156 (28%), Positives = 67/156 (42%), Gaps = 26/156 (16%)
Query: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVP-CNCNGHSNQCQDGSGICVNCQHNTAG 1712
C CPP G+ C+ P +G + C C H+ +C +G C+ C G
Sbjct: 758 CRCPPGRTGEDCEADCP------EGRWGLGCQEICPACQHAARCDPETGACL-CLPGFVG 810
Query: 1713 EHCER-CQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCER-CA 1770
C+ C G+YG + C H + ATG CSC G+TG C+R C
Sbjct: 811 SRCQDVCPAGWYGPSCQTRCSCANDGHCHP-ATG--------HCSCAPGWTGFSCQRACD 861
Query: 1771 PGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCI 1806
G++G PC+C++ GSC ++G C+
Sbjct: 862 TGHWG-----PDCSHPCNCSAGH--GSCDAISGLCL 890
Score = 58.2 bits (139), Expect = 1e-07
Identities = 53/167 (31%), Positives = 65/167 (38%), Gaps = 30/167 (17%)
Query: 1643 GSGRIALAVEICACPPAYAGDSC-QGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSG 1701
G G +C C Y G C Q C G++ G C C H C SG
Sbjct: 878 GHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFG------PGCEQRCQCQ-HGAACDHVSG 930
Query: 1702 ICVNCQHNTAGEHCER-CQEGYYGNAVHGSCR-ACPCPHTNSFATGCVVNGGDVRCSCKA 1759
C C G CE C G++G CR AC C + A VNG C C A
Sbjct: 931 AC-TCPAGWRGTFCEHACPAGFFGL----DCRSACNC---TAGAACDAVNGS---CLCPA 979
Query: 1760 GYTGTQCERCAPGYFGNPQKFGGSC-QPCSCNSNGQLGSCHPLTGDC 1805
G G +C P + +G +C Q C+C NG SC P+ G C
Sbjct: 980 GRRGPRCAETCPAH-----TYGHNCSQACAC-FNG--ASCDPVHGQC 1018
Score = 57.8 bits (138), Expect = 2e-07
Identities = 90/366 (24%), Positives = 112/366 (30%), Gaps = 92/366 (25%)
Query: 393 CQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADGCEQGSGRC--HCKPNFH 450
C +N G C G Y Y + D C C E D C G C HC N
Sbjct: 386 CTNNPGGYEC-----GCYAGYRLSADG------CGC--EDVDECASSRGGCEHHCT-NLA 431
Query: 451 GDNCEKCAIGYY--------------------NFPFCLRIPIFPVSTPS-----SEDPVA 485
G C GY PF +P V +D V
Sbjct: 432 GSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVG 491
Query: 486 GDIKGCDCNLEGVLPE--IC--DAHGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSAL 541
D + + E L E +C D+ G CD CR+G
Sbjct: 492 ADEEEAELRGEHTLTEKFVCLDDSFGHDCSLT------CDDCRNGG-------------- 531
Query: 542 GSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQC 601
C C+C G TG C+ +C S S C GT +S G C+C
Sbjct: 532 -----TCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCS-CQNGGTCDSVTGACRC 585
Query: 602 KLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGD 661
V G C + P G C K + G C + G C C + G
Sbjct: 586 PPGVSGTNC----------EDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGR 635
Query: 662 SCD-TCEDGYFALEKSNYFGC-QGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRP-E 718
C TC F GC + CQC S C G C C+ G+ CQ E
Sbjct: 636 FCHLTCPPWAFGP------GCSEECQCVQPHTQS--CDKRDGSCSCKAGFRGERCQAECE 687
Query: 719 NNYYFP 724
Y+ P
Sbjct: 688 LGYFGP 693
Score = 56.2 bits (134), Expect = 5e-07
Identities = 44/147 (29%), Positives = 53/147 (36%), Gaps = 13/147 (8%)
Query: 1275 GPHCSPEGGQCPCQPNVIGRQCTR-CATGHYGFPRCKPCSC-GRRLCEEMTGQCRCPPRT 1332
G C P G+C C G C R C G +G + C C G C+ +TG C CPP
Sbjct: 1396 GAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGR 1455
Query: 1333 VRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRC 1392
C + + F P C+C +CD SGQC C G C
Sbjct: 1456 SGATCNL-DCRRGQFGPSCTLH-CDCGGGA-------DCDPVSGQCHCVDGYMGPTCRE- 1505
Query: 1393 ASGFYRFPECVPCNCNRDGTEPGVCDP 1419
G R PE GT P P
Sbjct: 1506 -GGPLRLPENPSLAQGSAGTLPASSRP 1531
Score = 50.4 bits (119), Expect = 3e-05
Identities = 80/345 (23%), Positives = 113/345 (32%), Gaps = 89/345 (25%)
Query: 421 DGCIPCSCDPE---HADGCEQGSGR-CHCKPNFHGDNCE-----------KCAIGYYNFP 465
+GC+ C H C GS + CHC P F G C+ C N P
Sbjct: 121 EGCLSAECSASLCFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNTP 180
Query: 466 ---FCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGV----EGP 518
C P F + T S + + ++ RC CRPG +G
Sbjct: 181 GSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGR 240
Query: 519 RCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTG--QCECRPG----VTGQRCDRCLSG 572
C + ++ + GS C V G +CEC G G+ C+
Sbjct: 241 HC-----------VRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACE----- 284
Query: 573 AYDFPHCQGSSSACDPAGTINSNLGY-CQC----KLHVEGPTCSRCKLLYWNLDKENPSG 627
D C + C G +N+ + C C +L +G C R ++ N + N G
Sbjct: 285 --DVDECAAGLAQC-AHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGG 341
Query: 628 CSE----------CKCHKA-------GTVSGTGECRQGDGDC---HCKSHVGGDSCDTCE 667
CS C C + T +C D C C ++ GG C C
Sbjct: 342 CSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDC--ADSPCCQQVCTNNPGGYECG-CY 398
Query: 668 DGYFALEKSNYFGCQGCQC-DIGGALSSM------CSGPSGVCQC 705
GY GC C D+ SS C+ +G QC
Sbjct: 399 AGY-------RLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQC 436
Score = 49.7 bits (117), Expect = 5e-05
Identities = 53/193 (27%), Positives = 70/193 (36%), Gaps = 45/193 (23%)
Query: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVP------CNCNG----HS--------NQ 1695
C CPP + G CQ R H G RCV C C H+ N
Sbjct: 147 CHCPPGFQGPRCQ-YDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINS 205
Query: 1696 CQDGSGICV-NCQHNTAGEHCERCQEGYYGNAVHGSC-RACPCPHTN-SFATGCVVNGGD 1752
C G+G C +C T H +C+ G+ C R PC + N S C V G
Sbjct: 206 CALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGL 265
Query: 1753 VRCSCKAGY----TGTQCE----------RCAPGYFGNPQKFGGSCQPCSCNSNGQLGS- 1797
RC C GY G CE +CA G F C C++ +LG+
Sbjct: 266 ARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSF-----KCVCHAGYELGAD 320
Query: 1798 ---CHPLTGDCIN 1807
C+ + + +N
Sbjct: 321 GRQCYRIEMEIVN 333
Score = 47.8 bits (112), Expect = 2e-04
Identities = 50/180 (27%), Positives = 68/180 (37%), Gaps = 29/180 (16%)
Query: 1665 CQGCSPGYYRDHKGLYTGRCVPC-NCNGHS-NQCQDGSGIC-----VNCQHNTAGEHCER 1717
CQ C PG+ G + R PC N NG ++CQ G+ V Q G+ CE
Sbjct: 227 CQ-CRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACED 285
Query: 1718 CQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGY----TGTQCERCAPGY 1773
E G A C H GC+ G +C C AGY G QC R
Sbjct: 286 VDECAAGLA--------QCAH------GCLNTQGSFKCVCHAGYELGADGRQCYRIEMEI 331
Query: 1774 FGNPQKFGGSC-QPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMTLLND 1832
+ + G C CS S G L +C G ++ + + ++C D C N+
Sbjct: 332 VNSCEANNGGCSHGCSHTSAGPLCTCP--RGYELDTDQRTCIDVDDCADSPCCQQVCTNN 389
Score = 47.0 bits (110), Expect = 3e-04
Identities = 44/159 (27%), Positives = 54/159 (33%), Gaps = 46/159 (28%)
Query: 1650 AVEICACPPAYAGDSCQG-CSPGYY-RDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQ 1707
A C C P + G +C+ C PG++ +GL C C H C SG C+ C
Sbjct: 1359 ATGTCRCGPGFYGQACEHPCPPGFHGAGCQGL-------CWCQ-HGAPCDPISGRCL-CP 1409
Query: 1708 HNTAGEHCER-CQEGYYGNAVHGSCRA------------CPCPHTNSFAT---------- 1744
G CER C+ G +G H C C CP S AT
Sbjct: 1410 AGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQF 1469
Query: 1745 ------GCVVNGG------DVRCSCKAGYTGTQCERCAP 1771
C GG +C C GY G C P
Sbjct: 1470 GPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGGP 1508
Score = 45.4 bits (106), Expect = 0.001
Identities = 36/125 (28%), Positives = 56/125 (44%), Gaps = 22/125 (17%)
Query: 1688 NCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCV 1747
+C+ + C++G G C+ + C+ C EG+ G + +C SF+ C
Sbjct: 519 DCSLTCDDCRNG-GTCL-----LGLDGCD-CPEGWTGLICNETCPPDTFGKNCSFSCSCQ 571
Query: 1748 VNGGDV-----RCSCKAGYTGTQCE-RCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPL 1801
NGG C C G +GT CE C GY+G + + C+C + G+ CH L
Sbjct: 572 -NGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCR-----KKCNCANRGR---CHRL 622
Query: 1802 TGDCI 1806
G C+
Sbjct: 623 YGACL 627
Score = 44.3 bits (103), Expect = 0.002
Identities = 66/267 (24%), Positives = 89/267 (33%), Gaps = 74/267 (27%)
Query: 496 EGVLPEICDAH-----GRCL--------CRPGVEGPRC----DTCRSGFYSFPICQACWC 538
EG L C A GRC+ C PG +GPRC D CR+ CQ
Sbjct: 121 EGCLSAECSASLCFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECRTHNGG---CQHRCV 177
Query: 539 SALGSYQMPCSSVTGQCECRPG----VTGQRCDRCLSGAYDFPHCQ---------GSSSA 585
+ GSY CEC+PG + C S A CQ
Sbjct: 178 NTPGSY---------LCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQ 228
Query: 586 CDPAGTINSNLGYCQCK---LHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGT 642
C P + + +C + + G RC+++ G + C+CH ++
Sbjct: 229 CRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVV---------RGLARCECHVGYQLAAD 279
Query: 643 G-------ECRQGDGDC--HCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQC-DIGGAL 692
G EC G C C + G C C GY G G QC I +
Sbjct: 280 GKACEDVDECAAGLAQCAHGCLNTQGSFKC-VCHAGY-------ELGADGRQCYRIEMEI 331
Query: 693 SSMCSGPSGVCQ--CREHVVGKVCQRP 717
+ C +G C C G +C P
Sbjct: 332 VNSCEANNGGCSHGCSHTSAGPLCTCP 358
Score = 41.6 bits (96), Expect = 0.013
Identities = 32/112 (28%), Positives = 40/112 (35%), Gaps = 25/112 (22%)
Query: 1339 VCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQC------RCKPRITGRQCDRC 1392
VC SF C+ +C GT + CD G C P G+ C
Sbjct: 510 VCLDDSFGHDCSLTCD--DCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCS-- 565
Query: 1393 ASGFYRFPECVPCNCNRDGTEPGVCDPGTGACLCKENVEGTEC-NVCREGSF 1443
C+C GT CD TGAC C V GT C + C +G +
Sbjct: 566 ----------FSCSCQNGGT----CDSVTGACRCPPGVSGTNCEDGCPKGYY 603
Score = 41.2 bits (95), Expect = 0.017
Identities = 54/194 (27%), Positives = 69/194 (35%), Gaps = 37/194 (19%)
Query: 1634 VGLEEASDTGSGRIALAVEICACPPAYAGDSC---QG-----CSPGYYRDHKGLYTGRC- 1684
VG + A+D G+ V+ CA A C QG C GY G R
Sbjct: 272 VGYQLAAD---GKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIE 328
Query: 1685 --VPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSC-RACPCPHTNS 1741
+ +C ++ C G C H +AG C C GY + +C C +
Sbjct: 329 MEIVNSCEANNGGCSHG------CSHTSAGPLCT-CPRGYELDTDQRTCIDVDDCADSPC 381
Query: 1742 FATGCVVNGGDVRCSCKAGY----TGTQCE---RCAPGYFG---NPQKFGGSCQPCSCNS 1791
C N G C C AGY G CE CA G + GS Q CSC +
Sbjct: 382 CQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQ-CSCEA 440
Query: 1792 NGQL----GSCHPL 1801
+L C PL
Sbjct: 441 GYRLHEDRRGCSPL 454
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.422
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 141,114,678
Number of Sequences: 37866
Number of extensions: 7342603
Number of successful extensions: 33046
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 130
Number of HSP's successfully gapped in prelim test: 872
Number of HSP's that attempted gapping in prelim test: 19427
Number of HSP's gapped (non-prelim): 6530
length of query: 3333
length of database: 18,247,518
effective HSP length: 121
effective length of query: 3212
effective length of database: 13,665,732
effective search space: 43894331184
effective search space used: 43894331184
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 72 (32.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.