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Search of human proteins with 37588869
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|37588869 ring finger protein 123 [Homo sapiens]
(1314 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|37588869 ring finger protein 123 [Homo sapiens] 2633 0.0
gi|45387949 ring finger and SPRY domain containing 1 [Homo sapiens] 91 6e-18
gi|112799847 cardiac muscle ryanodine receptor [Homo sapiens] 82 3e-15
gi|4826686 DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 [Homo sapiens] 81 8e-15
gi|126032338 ryanodine receptor 3 [Homo sapiens] 77 1e-13
gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo ... 71 8e-12
gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo ... 71 8e-12
gi|21536320 heterogeneous nuclear ribonucleoprotein U-like 1 iso... 58 5e-08
gi|21536326 heterogeneous nuclear ribonucleoprotein U-like 1 iso... 58 5e-08
gi|40538736 RAN binding protein 10 [Homo sapiens] 58 7e-08
gi|39812378 RAN binding protein 9 [Homo sapiens] 53 2e-06
gi|157412282 ash2-like isoform b [Homo sapiens] 52 4e-06
gi|157412280 ash2-like isoform a [Homo sapiens] 52 4e-06
gi|14141161 heterogeneous nuclear ribonucleoprotein U isoform b ... 51 8e-06
gi|74136883 heterogeneous nuclear ribonucleoprotein U isoform a ... 51 8e-06
gi|118601081 heterogeneous nuclear ribonucleoprotein U-like 2 [H... 47 1e-04
gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo s... 41 0.009
gi|50233824 ring finger and WD repeat domain 2 isoform d24 [Homo... 41 0.009
gi|109134327 PTD016 protein [Homo sapiens] 40 0.011
gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens] 40 0.015
gi|18141316 splA/ryanodine receptor domain and SOCS box containi... 40 0.015
gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens] 40 0.019
gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens] 40 0.019
gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens] 40 0.019
gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens] 40 0.019
gi|62865649 rififylin [Homo sapiens] 39 0.043
gi|17432433 rififylin [Homo sapiens] 39 0.043
gi|4504867 ring finger protein 8 isoform 1 [Homo sapiens] 39 0.043
gi|20162564 tripartite motif-containing 40 [Homo sapiens] 39 0.043
gi|18254460 splA/ryanodine receptor domain and SOCS box containi... 39 0.043
>gi|37588869 ring finger protein 123 [Homo sapiens]
Length = 1314
Score = 2633 bits (6824), Expect = 0.0
Identities = 1314/1314 (100%), Positives = 1314/1314 (100%)
Query: 1 MASKGAGMSFSRKSYRLTSDAEKSRVTGIVQEKLLNDYLNRIFSSSEHAPPAATSRKPLN 60
MASKGAGMSFSRKSYRLTSDAEKSRVTGIVQEKLLNDYLNRIFSSSEHAPPAATSRKPLN
Sbjct: 1 MASKGAGMSFSRKSYRLTSDAEKSRVTGIVQEKLLNDYLNRIFSSSEHAPPAATSRKPLN 60
Query: 61 FQNLPEHLDQLLQVDNEEEESQGQVEGRLGPSTVVLDHTGGFEGLLLVDDDLLGVIGHSN 120
FQNLPEHLDQLLQVDNEEEESQGQVEGRLGPSTVVLDHTGGFEGLLLVDDDLLGVIGHSN
Sbjct: 61 FQNLPEHLDQLLQVDNEEEESQGQVEGRLGPSTVVLDHTGGFEGLLLVDDDLLGVIGHSN 120
Query: 121 FGTIRSTTCVYKGKWLYEVLISSQGLMQIGWCTISCRFNQEEGVGDTHNSYAYDGNRVRK 180
FGTIRSTTCVYKGKWLYEVLISSQGLMQIGWCTISCRFNQEEGVGDTHNSYAYDGNRVRK
Sbjct: 121 FGTIRSTTCVYKGKWLYEVLISSQGLMQIGWCTISCRFNQEEGVGDTHNSYAYDGNRVRK 180
Query: 181 WNVTTTNYGKAWAAGDIVSCLIDLDDGTLSFCLNGVSLGTAFENLSRGLGMAYFPAISLS 240
WNVTTTNYGKAWAAGDIVSCLIDLDDGTLSFCLNGVSLGTAFENLSRGLGMAYFPAISLS
Sbjct: 181 WNVTTTNYGKAWAAGDIVSCLIDLDDGTLSFCLNGVSLGTAFENLSRGLGMAYFPAISLS 240
Query: 241 FKESVAFNFGSRPLRYPVAGYRPLQDPPSADLVRAQRLLGCFRAVLSVELDPVEGRLLDK 300
FKESVAFNFGSRPLRYPVAGYRPLQDPPSADLVRAQRLLGCFRAVLSVELDPVEGRLLDK
Sbjct: 241 FKESVAFNFGSRPLRYPVAGYRPLQDPPSADLVRAQRLLGCFRAVLSVELDPVEGRLLDK 300
Query: 301 ESSKWRLRGQPTVLLTLAHIFHHFAPLLRKVYLVEAVLMSFLLGIVEKGTPTQAQSVVHQ 360
ESSKWRLRGQPTVLLTLAHIFHHFAPLLRKVYLVEAVLMSFLLGIVEKGTPTQAQSVVHQ
Sbjct: 301 ESSKWRLRGQPTVLLTLAHIFHHFAPLLRKVYLVEAVLMSFLLGIVEKGTPTQAQSVVHQ 360
Query: 361 VLDLLWLFMEDYEVQDCLKQLMMSLLRLYRFSPIVPDLGLQIHYLRLTIAILRHEKSRKF 420
VLDLLWLFMEDYEVQDCLKQLMMSLLRLYRFSPIVPDLGLQIHYLRLTIAILRHEKSRKF
Sbjct: 361 VLDLLWLFMEDYEVQDCLKQLMMSLLRLYRFSPIVPDLGLQIHYLRLTIAILRHEKSRKF 420
Query: 421 LLSNVLFDVLRSVVFFYIKSPLRVEEAGLQELIPTTWWPHCSSREGKESTEMKEETAEER 480
LLSNVLFDVLRSVVFFYIKSPLRVEEAGLQELIPTTWWPHCSSREGKESTEMKEETAEER
Sbjct: 421 LLSNVLFDVLRSVVFFYIKSPLRVEEAGLQELIPTTWWPHCSSREGKESTEMKEETAEER 480
Query: 481 LRRRAYERGCQRLRKRIEVVEELQVQILKLLLDNKDDNGGEASRYIFLTKFRKFLQENAS 540
LRRRAYERGCQRLRKRIEVVEELQVQILKLLLDNKDDNGGEASRYIFLTKFRKFLQENAS
Sbjct: 481 LRRRAYERGCQRLRKRIEVVEELQVQILKLLLDNKDDNGGEASRYIFLTKFRKFLQENAS 540
Query: 541 GRGNMPMLCPPEYMVCFLHRLISALRYYWDEYKASNPHASFSEEAYIPPQVFYNGKVDYF 600
GRGNMPMLCPPEYMVCFLHRLISALRYYWDEYKASNPHASFSEEAYIPPQVFYNGKVDYF
Sbjct: 541 GRGNMPMLCPPEYMVCFLHRLISALRYYWDEYKASNPHASFSEEAYIPPQVFYNGKVDYF 600
Query: 601 DLQRLGGLLSHLRKTLKDDLASKANIVIDPLELQSTAMDDLDEDEEPAPAMAQRPMQALA 660
DLQRLGGLLSHLRKTLKDDLASKANIVIDPLELQSTAMDDLDEDEEPAPAMAQRPMQALA
Sbjct: 601 DLQRLGGLLSHLRKTLKDDLASKANIVIDPLELQSTAMDDLDEDEEPAPAMAQRPMQALA 660
Query: 661 VGGPLPLPRPGWLSSPTLGRANRFLSTAAVSLMTPRRPLSTSEKVKVRTLSVEQRTREDI 720
VGGPLPLPRPGWLSSPTLGRANRFLSTAAVSLMTPRRPLSTSEKVKVRTLSVEQRTREDI
Sbjct: 661 VGGPLPLPRPGWLSSPTLGRANRFLSTAAVSLMTPRRPLSTSEKVKVRTLSVEQRTREDI 720
Query: 721 EGSHWNEGLLLGRPPEEPEQPLTENSLLEVLDGAVMMYNLSVHQQLGKMVGVSDDVNEYA 780
EGSHWNEGLLLGRPPEEPEQPLTENSLLEVLDGAVMMYNLSVHQQLGKMVGVSDDVNEYA
Sbjct: 721 EGSHWNEGLLLGRPPEEPEQPLTENSLLEVLDGAVMMYNLSVHQQLGKMVGVSDDVNEYA 780
Query: 781 MALRDTEDKLRRCPKRRKDILAELTKSQKVFSEKLDHLSRRLAWVHATVYSQEKMLDIYW 840
MALRDTEDKLRRCPKRRKDILAELTKSQKVFSEKLDHLSRRLAWVHATVYSQEKMLDIYW
Sbjct: 781 MALRDTEDKLRRCPKRRKDILAELTKSQKVFSEKLDHLSRRLAWVHATVYSQEKMLDIYW 840
Query: 841 LLRVCLRTIEHGDRTGSLFAFMPEFYLSVAINSYSALKNYFGPVHSMEELPGYEETLTRL 900
LLRVCLRTIEHGDRTGSLFAFMPEFYLSVAINSYSALKNYFGPVHSMEELPGYEETLTRL
Sbjct: 841 LLRVCLRTIEHGDRTGSLFAFMPEFYLSVAINSYSALKNYFGPVHSMEELPGYEETLTRL 900
Query: 901 AAILAKHFADARIVGTDIRDSLMQALASYVCYPHSLRAVERIPEEQRIAMVRNLLAPYEQ 960
AAILAKHFADARIVGTDIRDSLMQALASYVCYPHSLRAVERIPEEQRIAMVRNLLAPYEQ
Sbjct: 901 AAILAKHFADARIVGTDIRDSLMQALASYVCYPHSLRAVERIPEEQRIAMVRNLLAPYEQ 960
Query: 961 RPWAQTNWILVRLWRGCGFGYRYTRLPHLLKTKLEDANLPSLQKPCPSTLLQQHMADLLQ 1020
RPWAQTNWILVRLWRGCGFGYRYTRLPHLLKTKLEDANLPSLQKPCPSTLLQQHMADLLQ
Sbjct: 961 RPWAQTNWILVRLWRGCGFGYRYTRLPHLLKTKLEDANLPSLQKPCPSTLLQQHMADLLQ 1020
Query: 1021 QGPDVAPSFLNSVLNQLNWAFSEFIGMIQEIQQAAERLERNFVDSRQLKVCATCFDLSVS 1080
QGPDVAPSFLNSVLNQLNWAFSEFIGMIQEIQQAAERLERNFVDSRQLKVCATCFDLSVS
Sbjct: 1021 QGPDVAPSFLNSVLNQLNWAFSEFIGMIQEIQQAAERLERNFVDSRQLKVCATCFDLSVS 1080
Query: 1081 LLRVLEMTITLVPEIFLDWTRPTSEMLLRRLAQLLNQVLNRVTAERNLFDRVVTLRLPGL 1140
LLRVLEMTITLVPEIFLDWTRPTSEMLLRRLAQLLNQVLNRVTAERNLFDRVVTLRLPGL
Sbjct: 1081 LLRVLEMTITLVPEIFLDWTRPTSEMLLRRLAQLLNQVLNRVTAERNLFDRVVTLRLPGL 1140
Query: 1141 ESVDHYPILVAVTGILVQLLVRGPASEREQATSVLLADPCFQLRSICYLLGQPEPPAPGT 1200
ESVDHYPILVAVTGILVQLLVRGPASEREQATSVLLADPCFQLRSICYLLGQPEPPAPGT
Sbjct: 1141 ESVDHYPILVAVTGILVQLLVRGPASEREQATSVLLADPCFQLRSICYLLGQPEPPAPGT 1200
Query: 1201 ALPAPDRKRFSLQSYADYISADELAQVEQMLAHLTSASAQAAAASLPTSEEDLCPICYAH 1260
ALPAPDRKRFSLQSYADYISADELAQVEQMLAHLTSASAQAAAASLPTSEEDLCPICYAH
Sbjct: 1201 ALPAPDRKRFSLQSYADYISADELAQVEQMLAHLTSASAQAAAASLPTSEEDLCPICYAH 1260
Query: 1261 PISAVFQPCGHKSCKACINQHLMNNKDCFFCKTTIVSVEDWEKGANTSTTSSAA 1314
PISAVFQPCGHKSCKACINQHLMNNKDCFFCKTTIVSVEDWEKGANTSTTSSAA
Sbjct: 1261 PISAVFQPCGHKSCKACINQHLMNNKDCFFCKTTIVSVEDWEKGANTSTTSSAA 1314
>gi|45387949 ring finger and SPRY domain containing 1 [Homo sapiens]
Length = 576
Score = 91.3 bits (225), Expect = 6e-18
Identities = 53/143 (37%), Positives = 74/143 (51%), Gaps = 5/143 (3%)
Query: 119 SNFGTIRSTTCVYKGKWLYEVLISSQGLMQIGWCTISCRFNQEE--GVGDTHNSYAYDGN 176
S+F ++R T CV G W YEV + + G+MQIGW T +F E G+GD S AYDG
Sbjct: 345 SSFESVRCTFCVDAGVWYYEVTVVTSGVMQIGWATRDSKFLNHEGYGIGDDEYSCAYDGC 404
Query: 177 RVRKWNVTTT--NYGKAWAAGDIVSCLIDLDDGTLSFCLNGVSLGTAFENLSRGLGMAYF 234
R W + + W GD V L+DL++ + F LNG L + S + +F
Sbjct: 405 RQLIWYNARSKPHIHPCWKEGDTVGFLLDLNEKQMIFFLNGNQLPPEKQVFSSTVS-GFF 463
Query: 235 PAISLSFKESVAFNFGSRPLRYP 257
A S + FNFG++P +YP
Sbjct: 464 AAASFMSYQQCEFNFGAKPFKYP 486
>gi|112799847 cardiac muscle ryanodine receptor [Homo sapiens]
Length = 4967
Score = 82.4 bits (202), Expect = 3e-15
Identities = 40/128 (31%), Positives = 69/128 (53%), Gaps = 6/128 (4%)
Query: 127 TTCVYKGKWLYEVLISSQGLMQIGWCTISCRFNQEEGVGDTHNSYAYDGNRVRKWNVTTT 186
T V G+W +E + G M++GW C+ +QE +G ++A+DG + ++W+
Sbjct: 1093 TYAVKAGRWYFEFETVTAGDMRVGWSRPGCQPDQE--LGSDERAFAFDGFKAQRWHQGNE 1150
Query: 187 NYGKAWAAGDIVSCLIDLDDGTLSFCLNGVSL----GTAFENLSRGLGMAYFPAISLSFK 242
+YG++W AGD+V C++D+++ T+ F LNG L G+ +G + P SL
Sbjct: 1151 HYGRSWQAGDVVGCMVDMNEHTMMFTLNGEILLDDSGSELAFKDFDVGDGFIPVCSLGVA 1210
Query: 243 ESVAFNFG 250
+ NFG
Sbjct: 1211 QVGRMNFG 1218
Score = 50.4 bits (119), Expect = 1e-05
Identities = 59/211 (27%), Positives = 87/211 (41%), Gaps = 48/211 (22%)
Query: 134 KWLYEVLI--------SSQGLMQIGWCTISCRF----NQEE----GVGDTHNSYAYDGNR 177
KW YE+++ + +++GW + EE GVGD SY +DG
Sbjct: 672 KWYYELMVDHTEPFVTAEATHLRVGWASTEGYSPYPGGGEEWGGNGVGDDLFSYGFDG-- 729
Query: 178 VRKWN------VTTTNYGKAWAAGDIVSCLIDLDDGTLSFCLNGVSLGTAFENLSRGLGM 231
+ W+ V++ N D++SC +DL ++SF +NG + FEN + +
Sbjct: 730 LHLWSGCIARTVSSPNQ-HLLRTDDVISCCLDLSAPSISFRINGQPVQGMFENFN--IDG 786
Query: 232 AYFPAISLSFKESVAFNFGSRPLRY---PVAGYRPLQDPPSADLVRAQRLLGCFRAVLSV 288
+FP +S S V F G R + P GY P C+ AVL
Sbjct: 787 LFFPVVSFSAGIKVRFLLGGRHGEFKFLPPPGYAP-----------------CYEAVLPK 829
Query: 289 ELDPVE-GRLLDKESSKWRLRGQPTVLLTLA 318
E VE R +E + R PTV LT A
Sbjct: 830 EKLKVEHSREYKQERTYTRDLLGPTVSLTQA 860
>gi|4826686 DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 [Homo sapiens]
Length = 740
Score = 80.9 bits (198), Expect = 8e-15
Identities = 49/153 (32%), Positives = 72/153 (47%), Gaps = 6/153 (3%)
Query: 125 RSTTCVYKGKWLYEVLISSQGLMQIGWCTISCRFNQEEGVGDTHNSYAYDGNRVRKWNVT 184
R+T + KGK YEV QGL ++GW T+ + +G + + G + N
Sbjct: 123 RATKGLMKGKHYYEVSCHDQGLCRVGWSTMQASLD----LGTDKFGFGFGGTGKKSHNKQ 178
Query: 185 TTNYGKAWAAGDIVSCLIDLDDGTLSFCLNGVSLGTAFENLSRGLGMAYFPAISLSFKES 244
NYG+ + D + C +D+D G + F NG LG AFE A FPA L E
Sbjct: 179 FDNYGEEFTMHDTIGCYLDIDKGHVKFSKNGKDLGLAFEIPPHMKNQALFPACVLKNAE- 237
Query: 245 VAFNFGSRPLRYPVA-GYRPLQDPPSADLVRAQ 276
+ FNFG ++P G+ L P +V++Q
Sbjct: 238 LKFNFGEEEFKFPPKDGFVALSKAPDGYIVKSQ 270
>gi|126032338 ryanodine receptor 3 [Homo sapiens]
Length = 4870
Score = 77.0 bits (188), Expect = 1e-13
Identities = 35/100 (35%), Positives = 58/100 (58%), Gaps = 2/100 (2%)
Query: 121 FGTIRSTTCVYKGKWLYEVLISSQGLMQIGWCTISCRFNQEEGVGDTHNSYAYDGNRVRK 180
F + + V GKW +E + + G M++GW CR + E G D ++ ++GNR ++
Sbjct: 1073 FFRVERSYAVRSGKWYFEFEVVTGGDMRVGWARPGCRPDVELGADD--QAFVFEGNRGQR 1130
Query: 181 WNVTTTNYGKAWAAGDIVSCLIDLDDGTLSFCLNGVSLGT 220
W+ + +G+ W GD+V C+I+LDD ++ F LNG L T
Sbjct: 1131 WHQGSGYFGRTWQPGDVVGCMINLDDASMIFTLNGELLIT 1170
Score = 47.0 bits (110), Expect = 1e-04
Identities = 45/156 (28%), Positives = 69/156 (44%), Gaps = 32/156 (20%)
Query: 134 KWLYEVLI--------SSQGLMQIGWCTISCRFNQE--------EGVGDTHNSYAYDGNR 177
KW +E++I + +++GW + S GVGD SY +DG
Sbjct: 659 KWYFELIIDQVDPFLTAEPTHLRVGWASSSGYAPYPGGGEGWGGNGVGDDLYSYGFDG-- 716
Query: 178 VRKWN------VTTTNYGKAWAAGDIVSCLIDLDDGTLSFCLNGVSLGTAFENLSR-GLG 230
+ W+ V + N + D+VSC +DL ++SF +NG + FEN + GL
Sbjct: 717 LHLWSGRIPRAVASINQ-HLLRSDDVVSCCLDLGVPSISFRINGQPVQGMFENFNTDGL- 774
Query: 231 MAYFPAISLSFKESVAFNFGSRPLRY---PVAGYRP 263
+FP +S S V F G R + P +GY P
Sbjct: 775 --FFPVMSFSAGVKVRFLMGGRHGEFKFLPPSGYAP 808
Score = 33.1 bits (74), Expect = 1.8
Identities = 19/52 (36%), Positives = 25/52 (48%), Gaps = 3/52 (5%)
Query: 198 VSCLIDLDDGTLSFCLNGVSLGTAFENLSRGLGMAYFPAISLSFKESVAFNF 249
+ CL+DL G LSF NG LGT ++ FPA+ L + F F
Sbjct: 1411 IGCLVDLAMGMLSFSANGKELGTCYQVEP---NTKVFPAVFLQPTSTSLFQF 1459
>gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo
sapiens]
Length = 5033
Score = 70.9 bits (172), Expect = 8e-12
Identities = 39/127 (30%), Positives = 65/127 (51%), Gaps = 10/127 (7%)
Query: 130 VYKGKWLYEVLISSQGLMQIGWCTISCRFNQEEGVGDTHNSYAYDGNRVRKWNVTTTNYG 189
V G+W +E + G M++GW R + E G + +Y ++G+R ++W++ + +G
Sbjct: 1082 VQSGRWYFEFEAVTTGEMRVGWARPELRPDVELGADEL--AYVFNGHRGQRWHLGSEPFG 1139
Query: 190 KAWAAGDIVSCLIDLDDGTLSFCLNGVSL------GTAFENLSRGLGMAYFPAISLSFKE 243
+ W GD+V C+IDL + T+ F LNG L TAF + +G + P SL +
Sbjct: 1140 RPWQPGDVVGCMIDLTENTIIFTLNGEVLMSDSGSETAFREIE--IGDGFLPVCSLGPGQ 1197
Query: 244 SVAFNFG 250
N G
Sbjct: 1198 VGHLNLG 1204
Score = 49.3 bits (116), Expect = 2e-05
Identities = 36/110 (32%), Positives = 54/110 (49%), Gaps = 8/110 (7%)
Query: 163 GVGDTHNSYAYDGNRVRKWNVT--TTNYGK-AWAAGDIVSCLIDLDDGTLSFCLNGVSLG 219
GVGD SY +DG + +V T+ G+ A D++SC +DL ++SF +NG +
Sbjct: 705 GVGDDLYSYGFDGLHLWTGHVARPVTSPGQHLLAPEDVISCCLDLSVPSISFRINGCPVQ 764
Query: 220 TAFENLSRGLGMAYFPAISLSFKESVAFNFGSRPLRY---PVAGYRPLQD 266
FE+ + L +FP +S S V F G R + P GY P +
Sbjct: 765 GVFESFN--LDGLFFPVVSFSAGVKVRFLLGGRHGEFKFLPPPGYAPCHE 812
>gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo
sapiens]
Length = 5038
Score = 70.9 bits (172), Expect = 8e-12
Identities = 39/127 (30%), Positives = 65/127 (51%), Gaps = 10/127 (7%)
Query: 130 VYKGKWLYEVLISSQGLMQIGWCTISCRFNQEEGVGDTHNSYAYDGNRVRKWNVTTTNYG 189
V G+W +E + G M++GW R + E G + +Y ++G+R ++W++ + +G
Sbjct: 1082 VQSGRWYFEFEAVTTGEMRVGWARPELRPDVELGADEL--AYVFNGHRGQRWHLGSEPFG 1139
Query: 190 KAWAAGDIVSCLIDLDDGTLSFCLNGVSL------GTAFENLSRGLGMAYFPAISLSFKE 243
+ W GD+V C+IDL + T+ F LNG L TAF + +G + P SL +
Sbjct: 1140 RPWQPGDVVGCMIDLTENTIIFTLNGEVLMSDSGSETAFREIE--IGDGFLPVCSLGPGQ 1197
Query: 244 SVAFNFG 250
N G
Sbjct: 1198 VGHLNLG 1204
Score = 49.3 bits (116), Expect = 2e-05
Identities = 36/110 (32%), Positives = 54/110 (49%), Gaps = 8/110 (7%)
Query: 163 GVGDTHNSYAYDGNRVRKWNVT--TTNYGK-AWAAGDIVSCLIDLDDGTLSFCLNGVSLG 219
GVGD SY +DG + +V T+ G+ A D++SC +DL ++SF +NG +
Sbjct: 705 GVGDDLYSYGFDGLHLWTGHVARPVTSPGQHLLAPEDVISCCLDLSVPSISFRINGCPVQ 764
Query: 220 TAFENLSRGLGMAYFPAISLSFKESVAFNFGSRPLRY---PVAGYRPLQD 266
FE+ + L +FP +S S V F G R + P GY P +
Sbjct: 765 GVFESFN--LDGLFFPVVSFSAGVKVRFLLGGRHGEFKFLPPPGYAPCHE 812
>gi|21536320 heterogeneous nuclear ribonucleoprotein U-like 1
isoform d [Homo sapiens]
Length = 756
Score = 58.2 bits (139), Expect = 5e-08
Identities = 43/135 (31%), Positives = 63/135 (46%), Gaps = 11/135 (8%)
Query: 146 LMQIGWCTISCRFNQEEGVGDTHNSYAYDGNRVRKWNVTTTNYGKAWAAGDIVSCLIDLD 205
+++IGW SC +G+ SY Y G + N NYG +A D++ C D +
Sbjct: 181 VVRIGWSLDSCSTQ----LGEEPFSYGYGGTGKKSTNSRFENYGDKFAENDVIGCFADFE 236
Query: 206 DGT---LSFCLNGVSLGTAFENLSRGL-GMAYFPAISLSFKESVAFNFGSR--PLRYPVA 259
G LSF NG +G AF L G A +P + L +V FNFG R P +
Sbjct: 237 CGNDVELSFTKNGKWMGIAFRIQKEALGGQALYPHV-LVKNCAVEFNFGQRAEPYCSVLP 295
Query: 260 GYRPLQDPPSADLVR 274
G+ +Q P ++ +R
Sbjct: 296 GFTFIQHLPLSERIR 310
>gi|21536326 heterogeneous nuclear ribonucleoprotein U-like 1
isoform a [Homo sapiens]
Length = 856
Score = 58.2 bits (139), Expect = 5e-08
Identities = 43/135 (31%), Positives = 63/135 (46%), Gaps = 11/135 (8%)
Query: 146 LMQIGWCTISCRFNQEEGVGDTHNSYAYDGNRVRKWNVTTTNYGKAWAAGDIVSCLIDLD 205
+++IGW SC +G+ SY Y G + N NYG +A D++ C D +
Sbjct: 281 VVRIGWSLDSCSTQ----LGEEPFSYGYGGTGKKSTNSRFENYGDKFAENDVIGCFADFE 336
Query: 206 DGT---LSFCLNGVSLGTAFENLSRGL-GMAYFPAISLSFKESVAFNFGSR--PLRYPVA 259
G LSF NG +G AF L G A +P + L +V FNFG R P +
Sbjct: 337 CGNDVELSFTKNGKWMGIAFRIQKEALGGQALYPHV-LVKNCAVEFNFGQRAEPYCSVLP 395
Query: 260 GYRPLQDPPSADLVR 274
G+ +Q P ++ +R
Sbjct: 396 GFTFIQHLPLSERIR 410
>gi|40538736 RAN binding protein 10 [Homo sapiens]
Length = 620
Score = 57.8 bits (138), Expect = 7e-08
Identities = 47/152 (30%), Positives = 72/152 (47%), Gaps = 14/152 (9%)
Query: 118 HSNFGTIRSTTCVYK--GKWLYEVLISSQG---LMQIGWCTISCRFNQEEGVGDTHNSYA 172
H + ++R+T + G + +EV I S+G M IG N+ G D H SY
Sbjct: 84 HKDAASVRATHPIPAACGIYYFEVKIVSKGRDGYMGIGLSAQGVNMNRLPG-WDKH-SYG 141
Query: 173 YDGNRVRKWNVTTTN--YGKAWAAGDIVSCLIDLDDGTLSFCLNGVSLGTAFENLSRGLG 230
Y G+ + + T YG + GD++ C ++L +GT + NG SLG AF +L L
Sbjct: 142 YHGDDGHSFCSSGTGQPYGPTFTTGDVIGCCVNLINGTCFYTKNGHSLGIAFTDLPANL- 200
Query: 231 MAYFPAISLSFK-ESVAFNFGSRPLRYPVAGY 261
+P + L E V NFG +P + + Y
Sbjct: 201 ---YPTVGLQTPGEIVDANFGQQPFLFDIEDY 229
>gi|39812378 RAN binding protein 9 [Homo sapiens]
Length = 729
Score = 53.1 bits (126), Expect = 2e-06
Identities = 43/135 (31%), Positives = 62/135 (45%), Gaps = 12/135 (8%)
Query: 133 GKWLYEVLISSQG---LMQIGWCTISCRFNQEEGVGDTHNSYAYDGNRVRKWNVTTTN-- 187
G + +EV I S+G M IG N+ G D H SY Y G+ + + T
Sbjct: 213 GIYYFEVKIVSKGRDGYMGIGLSAQGVNMNRLPG-WDKH-SYGYHGDDGHSFCSSGTGQP 270
Query: 188 YGKAWAAGDIVSCLIDLDDGTLSFCLNGVSLGTAFENLSRGLGMAYFPAISLSFK-ESVA 246
YG + GD++ C ++L + T + NG SLG AF +L L +P + L E V
Sbjct: 271 YGPTFTTGDVIGCCVNLINNTCFYTKNGHSLGIAFTDLPPNL----YPTVGLQTPGEVVD 326
Query: 247 FNFGSRPLRYPVAGY 261
NFG P + + Y
Sbjct: 327 ANFGQHPFVFDIEDY 341
>gi|157412282 ash2-like isoform b [Homo sapiens]
Length = 534
Score = 52.0 bits (123), Expect = 4e-06
Identities = 49/211 (23%), Positives = 85/211 (40%), Gaps = 56/211 (26%)
Query: 106 LLVDDDLLGVIGHSNFGTIRSTTCVYKGKWLYEVLISS---QGLMQIGWCTISCRFNQEE 162
L + DD L V+G + +R++ V KG W +E+ + ++GW N +
Sbjct: 298 LKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEITVDEMPPDTAARLGWS--QPLGNLQA 355
Query: 163 GVGDTHNSYAYDGNRVRKWNVTT-TNYGKAWAAGDIVSCLIDLDDGT------------- 208
+G SY++ + K++ + +Y + GD++ I+L + T
Sbjct: 356 PLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDK 415
Query: 209 -------------------------------LSFCLNGVSLGTAFENLSRGLGMAYFPAI 237
+ F NGV+ G A++++ G+ YFPAI
Sbjct: 416 ALIKFKSYLYFEEKDFVDKAEKSLKQTPHSEIIFYKNGVNQGVAYKDIFEGV---YFPAI 472
Query: 238 SLSFKESVAFNFGSRPLRYPVAG--YRPLQD 266
SL +V+ NFG +YP YRP+ D
Sbjct: 473 SLYKSCTVSINFGP-CFKYPPKDLTYRPMSD 502
>gi|157412280 ash2-like isoform a [Homo sapiens]
Length = 628
Score = 52.0 bits (123), Expect = 4e-06
Identities = 49/211 (23%), Positives = 85/211 (40%), Gaps = 56/211 (26%)
Query: 106 LLVDDDLLGVIGHSNFGTIRSTTCVYKGKWLYEVLISS---QGLMQIGWCTISCRFNQEE 162
L + DD L V+G + +R++ V KG W +E+ + ++GW N +
Sbjct: 392 LKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEITVDEMPPDTAARLGWS--QPLGNLQA 449
Query: 163 GVGDTHNSYAYDGNRVRKWNVTT-TNYGKAWAAGDIVSCLIDLDDGT------------- 208
+G SY++ + K++ + +Y + GD++ I+L + T
Sbjct: 450 PLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDK 509
Query: 209 -------------------------------LSFCLNGVSLGTAFENLSRGLGMAYFPAI 237
+ F NGV+ G A++++ G+ YFPAI
Sbjct: 510 ALIKFKSYLYFEEKDFVDKAEKSLKQTPHSEIIFYKNGVNQGVAYKDIFEGV---YFPAI 566
Query: 238 SLSFKESVAFNFGSRPLRYPVAG--YRPLQD 266
SL +V+ NFG +YP YRP+ D
Sbjct: 567 SLYKSCTVSINFGP-CFKYPPKDLTYRPMSD 596
>gi|14141161 heterogeneous nuclear ribonucleoprotein U isoform b
[Homo sapiens]
Length = 806
Score = 50.8 bits (120), Expect = 8e-06
Identities = 37/119 (31%), Positives = 58/119 (48%), Gaps = 6/119 (5%)
Query: 164 VGDTHNSYAYDGNRVRKWNVTTTNYGKAWAAGDIVSCL--IDLDDGTLSFCLNGVSLGTA 221
+G+ SY Y ++ N T +YG+ + D+++C + D+ LS+ NG LG A
Sbjct: 353 LGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFESDEVELSYAKNGQDLGVA 412
Query: 222 FENLSRGL-GMAYFPAISLSFKESVAFNFGSRPLRY-PV-AGYRPLQDPPSADLVRAQR 277
F+ L G FP + L +V FNFG + Y P+ Y +Q+ P D VR +
Sbjct: 413 FKISKEVLAGRPLFPHV-LCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVPLEDRVRGPK 470
>gi|74136883 heterogeneous nuclear ribonucleoprotein U isoform a
[Homo sapiens]
Length = 825
Score = 50.8 bits (120), Expect = 8e-06
Identities = 37/119 (31%), Positives = 58/119 (48%), Gaps = 6/119 (5%)
Query: 164 VGDTHNSYAYDGNRVRKWNVTTTNYGKAWAAGDIVSCL--IDLDDGTLSFCLNGVSLGTA 221
+G+ SY Y ++ N T +YG+ + D+++C + D+ LS+ NG LG A
Sbjct: 372 LGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFESDEVELSYAKNGQDLGVA 431
Query: 222 FENLSRGL-GMAYFPAISLSFKESVAFNFGSRPLRY-PV-AGYRPLQDPPSADLVRAQR 277
F+ L G FP + L +V FNFG + Y P+ Y +Q+ P D VR +
Sbjct: 432 FKISKEVLAGRPLFPHV-LCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVPLEDRVRGPK 489
>gi|118601081 heterogeneous nuclear ribonucleoprotein U-like 2 [Homo
sapiens]
Length = 747
Score = 47.0 bits (110), Expect = 1e-04
Identities = 31/110 (28%), Positives = 53/110 (48%), Gaps = 16/110 (14%)
Query: 125 RSTTCVYKGKWLYEVLISSQ----------GLMQIGWCTISCRFNQEEGVGDTHNSYAYD 174
RST V KGK +E ++ L+++GW S F++ + +G+ SY +D
Sbjct: 282 RSTYGVTKGKVCFEAKVTQNLPMKEGCTEVSLLRVGW---SVDFSRPQ-LGEDEFSYGFD 337
Query: 175 GNRVRKWNVTTTNYGKAWAAGDIVSCL--IDLDDGTLSFCLNGVSLGTAF 222
G ++ N +G+ + D++ C + ++ LSF NG LG AF
Sbjct: 338 GRGLKAENGQFEEFGQTFGENDVIGCFANFETEEVELSFSKNGEDLGVAF 387
>gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo
sapiens]
Length = 731
Score = 40.8 bits (94), Expect = 0.009
Identities = 17/51 (33%), Positives = 26/51 (50%)
Query: 1249 SEEDLCPICYAHPISAVFQPCGHKSCKACINQHLMNNKDCFFCKTTIVSVE 1299
S + +CPIC+ A CGH C CI+Q L +N C C + +++
Sbjct: 131 SNDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNID 181
>gi|50233824 ring finger and WD repeat domain 2 isoform d24 [Homo
sapiens]
Length = 707
Score = 40.8 bits (94), Expect = 0.009
Identities = 17/51 (33%), Positives = 26/51 (50%)
Query: 1249 SEEDLCPICYAHPISAVFQPCGHKSCKACINQHLMNNKDCFFCKTTIVSVE 1299
S + +CPIC+ A CGH C CI+Q L +N C C + +++
Sbjct: 131 SNDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNID 181
>gi|109134327 PTD016 protein [Homo sapiens]
Length = 435
Score = 40.4 bits (93), Expect = 0.011
Identities = 23/76 (30%), Positives = 34/76 (44%), Gaps = 2/76 (2%)
Query: 1235 TSASAQAAAASLPTSE-EDLCPICYAHPISAVFQPCGHKSCKACINQHLMNNKDCFFCKT 1293
T S AA+ S+ +D+C IC A + C H C+ C+ K C C+T
Sbjct: 355 TQPSYGVAASKRQCSDVDDICSICQAEFQKPILLICQHIFCEECMTLWFNREKTCPLCRT 414
Query: 1294 TIVS-VEDWEKGANTS 1308
I + W+ GA +S
Sbjct: 415 VISDHINKWKDGATSS 430
>gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens]
Length = 285
Score = 40.0 bits (92), Expect = 0.015
Identities = 23/73 (31%), Positives = 38/73 (52%), Gaps = 3/73 (4%)
Query: 768 KMVGVSDDVNEYAMALRDTEDKLRRCPKRRKDILAE---LTKSQKVFSEKLDHLSRRLAW 824
K+ G D++++Y+ AL+D ++KL K+ D AE L + ++ E+LD RLA
Sbjct: 50 KLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLAT 109
Query: 825 VHATVYSQEKMLD 837
+ EK D
Sbjct: 110 ALQKLEEAEKAAD 122
>gi|18141316 splA/ryanodine receptor domain and SOCS box containing
1 [Homo sapiens]
Length = 273
Score = 40.0 bits (92), Expect = 0.015
Identities = 26/85 (30%), Positives = 39/85 (45%), Gaps = 13/85 (15%)
Query: 164 VGDTHNSYAYDGNRVRKWNVTTTNYGKAWAA----------GDIVSCLIDLDDGTLSFCL 213
VG+ H S+ +D R R ++ K + A D +D+DDGTLSF +
Sbjct: 133 VGNNHESWGWDLGRNRLYHDGKNQPSKTYPAFLEPDETFIVPDSFLVALDMDDGTLSFIV 192
Query: 214 NGVSLGTAFENLSRGLGMAYFPAIS 238
+G +G AF L G +P +S
Sbjct: 193 DGQYMGVAFRGLK---GKKLYPVVS 214
>gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens]
Length = 284
Score = 39.7 bits (91), Expect = 0.019
Identities = 22/73 (30%), Positives = 38/73 (52%), Gaps = 3/73 (4%)
Query: 768 KMVGVSDDVNEYAMALRDTEDKLRRCPKRRKDI---LAELTKSQKVFSEKLDHLSRRLAW 824
K+ G D++++Y+ AL+D ++KL K+ D +A L + ++ E+LD RLA
Sbjct: 49 KLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLAT 108
Query: 825 VHATVYSQEKMLD 837
+ EK D
Sbjct: 109 ALQKLEEAEKAAD 121
>gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens]
Length = 284
Score = 39.7 bits (91), Expect = 0.019
Identities = 22/73 (30%), Positives = 38/73 (52%), Gaps = 3/73 (4%)
Query: 768 KMVGVSDDVNEYAMALRDTEDKLRRCPKRRKDI---LAELTKSQKVFSEKLDHLSRRLAW 824
K+ G D++++Y+ AL+D ++KL K+ D +A L + ++ E+LD RLA
Sbjct: 49 KLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLAT 108
Query: 825 VHATVYSQEKMLD 837
+ EK D
Sbjct: 109 ALQKLEEAEKAAD 121
>gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens]
Length = 284
Score = 39.7 bits (91), Expect = 0.019
Identities = 22/73 (30%), Positives = 38/73 (52%), Gaps = 3/73 (4%)
Query: 768 KMVGVSDDVNEYAMALRDTEDKLRRCPKRRKDI---LAELTKSQKVFSEKLDHLSRRLAW 824
K+ G D++++Y+ AL+D ++KL K+ D +A L + ++ E+LD RLA
Sbjct: 49 KLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLAT 108
Query: 825 VHATVYSQEKMLD 837
+ EK D
Sbjct: 109 ALQKLEEAEKAAD 121
>gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens]
Length = 284
Score = 39.7 bits (91), Expect = 0.019
Identities = 22/73 (30%), Positives = 38/73 (52%), Gaps = 3/73 (4%)
Query: 768 KMVGVSDDVNEYAMALRDTEDKLRRCPKRRKDI---LAELTKSQKVFSEKLDHLSRRLAW 824
K+ G D++++Y+ AL+D ++KL K+ D +A L + ++ E+LD RLA
Sbjct: 49 KLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLAT 108
Query: 825 VHATVYSQEKMLD 837
+ EK D
Sbjct: 109 ALQKLEEAEKAAD 121
>gi|62865649 rififylin [Homo sapiens]
Length = 363
Score = 38.5 bits (88), Expect = 0.043
Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 6/68 (8%)
Query: 1231 LAHLTSASAQAAAASLPTS-EEDLCPICYAHPISAVFQPCGHK-SCKACINQHLMNNKDC 1288
L HL S + ++P+ EE+LC IC PI V CGH +C C + MN +C
Sbjct: 292 LQHLVSGAEDQNGGAVPSGLEENLCKICMDSPIDCVLLECGHMVTCTKCGKR--MN--EC 347
Query: 1289 FFCKTTIV 1296
C+ ++
Sbjct: 348 PICRQYVI 355
>gi|17432433 rififylin [Homo sapiens]
Length = 363
Score = 38.5 bits (88), Expect = 0.043
Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 6/68 (8%)
Query: 1231 LAHLTSASAQAAAASLPTS-EEDLCPICYAHPISAVFQPCGHK-SCKACINQHLMNNKDC 1288
L HL S + ++P+ EE+LC IC PI V CGH +C C + MN +C
Sbjct: 292 LQHLVSGAEDQNGGAVPSGLEENLCKICMDSPIDCVLLECGHMVTCTKCGKR--MN--EC 347
Query: 1289 FFCKTTIV 1296
C+ ++
Sbjct: 348 PICRQYVI 355
>gi|4504867 ring finger protein 8 isoform 1 [Homo sapiens]
Length = 485
Score = 38.5 bits (88), Expect = 0.043
Identities = 22/73 (30%), Positives = 31/73 (42%), Gaps = 10/73 (13%)
Query: 1225 AQVEQMLAHLTSASAQAAAASLPTSEEDLCPICYAHPISAVFQPCGHKSCKACINQHLMN 1284
AQ E++L+H+ E C IC + I AV C H C CIN+ +
Sbjct: 384 AQKEEVLSHMNDV----------LENELQCIICSEYFIEAVTLNCAHSFCSYCINEWMKR 433
Query: 1285 NKDCFFCKTTIVS 1297
+C C+ I S
Sbjct: 434 KIECPICRKDIKS 446
>gi|20162564 tripartite motif-containing 40 [Homo sapiens]
Length = 229
Score = 38.5 bits (88), Expect = 0.043
Identities = 15/33 (45%), Positives = 19/33 (57%)
Query: 1250 EEDLCPICYAHPISAVFQPCGHKSCKACINQHL 1282
EE +CPIC AV CGH C+ C+ QH+
Sbjct: 10 EEGVCPICQESLKEAVSTNCGHLFCRVCLTQHV 42
>gi|18254460 splA/ryanodine receptor domain and SOCS box containing
4 [Homo sapiens]
Length = 273
Score = 38.5 bits (88), Expect = 0.043
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 13/85 (15%)
Query: 164 VGDTHNSYAYDGNRVRKWNVTTTNYG----------KAWAAGDIVSCLIDLDDGTLSFCL 213
VG S+ +D R R ++ G +A+A D + ++D+D+GTLSF +
Sbjct: 133 VGSDAESWGWDLGRSRLYHDGKNQPGVAYPAFLGPDEAFALPDSLLVVLDMDEGTLSFIV 192
Query: 214 NGVSLGTAFENLSRGLGMAYFPAIS 238
+G LG AF L G +P +S
Sbjct: 193 DGQYLGVAFRGLK---GKKLYPVVS 214
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,289,363
Number of Sequences: 37866
Number of extensions: 2323225
Number of successful extensions: 8335
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 93
Number of HSP's successfully gapped in prelim test: 83
Number of HSP's that attempted gapping in prelim test: 8129
Number of HSP's gapped (non-prelim): 265
length of query: 1314
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1200
effective length of database: 13,930,794
effective search space: 16716952800
effective search space used: 16716952800
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.