Search of human proteins with 37577148

Search of human proteins with 37577148

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|37577148 NCK interacting protein with SH3 domain isoform 2
[Homo sapiens]
         (715 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|37577148 NCK interacting protein with SH3 domain isoform 2 [H...  1416   0.0  
gi|7705266 NCK interacting protein with SH3 domain isoform 1 [Ho...  1409   0.0  
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        54   4e-07
gi|23510364 protein-tyrosine kinase fyn isoform c [Homo sapiens]       48   3e-05
gi|23510362 protein-tyrosine kinase fyn isoform b [Homo sapiens]       48   3e-05
gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens]        48   3e-05
gi|130977759 tec protein tyrosine kinase [Homo sapiens]                48   4e-05
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         46   1e-04
gi|15718680 IL2-inducible T-cell kinase [Homo sapiens]                 46   1e-04
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]         45   2e-04
gi|38683860 insulin receptor substrate 2 [Homo sapiens]                45   2e-04
gi|148596974 TXK tyrosine kinase [Homo sapiens]                        45   2e-04
gi|38202217 proto-oncogene tyrosine-protein kinase SRC [Homo sap...    44   4e-04
gi|4885609 proto-oncogene tyrosine-protein kinase SRC [Homo sapi...    44   4e-04
gi|161169015 neuron navigator 2 isoform 3 [Homo sapiens]               44   4e-04
gi|161169013 neuron navigator 2 isoform 1 [Homo sapiens]               44   4e-04
gi|38044282 neuron navigator 2 isoform 2 [Homo sapiens]                44   4e-04
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap...    44   7e-04
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    44   7e-04
gi|20143482 melanoma antigen family E, 1 [Homo sapiens]                44   7e-04
gi|112382244 proto-oncogene tyrosine-protein kinase FGR [Homo sa...    44   7e-04
gi|112382241 proto-oncogene tyrosine-protein kinase FGR [Homo sa...    44   7e-04
gi|4885235 proto-oncogene tyrosine-protein kinase FGR [Homo sapi...    44   7e-04
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    44   7e-04
gi|68348709 formin binding protein 1-like isoform 1 [Homo sapiens]     43   9e-04
gi|41581463 formin binding protein 1-like isoform 2 [Homo sapiens]     43   9e-04
gi|39930351 dynamin binding protein [Homo sapiens]                     43   9e-04
gi|20149528 proline-serine-threonine phosphatase interacting pro...    43   9e-04
gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo...    43   9e-04
gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo...    43   9e-04

>gi|37577148 NCK interacting protein with SH3 domain isoform 2 [Homo
           sapiens]
          Length = 715

 Score = 1416 bits (3665), Expect = 0.0
 Identities = 715/715 (100%), Positives = 715/715 (100%)

Query: 1   MYRALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGETGYVPPAYLRRLQGLE 60
           MYRALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGETGYVPPAYLRRLQGLE
Sbjct: 1   MYRALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGETGYVPPAYLRRLQGLE 60

Query: 61  QDVLQAIDRAIEAVHNTAMRDGGKYSLEQRGVLQKLIHHRKETLSRRGPSASSVAVMTSS 120
           QDVLQAIDRAIEAVHNTAMRDGGKYSLEQRGVLQKLIHHRKETLSRRGPSASSVAVMTSS
Sbjct: 61  QDVLQAIDRAIEAVHNTAMRDGGKYSLEQRGVLQKLIHHRKETLSRRGPSASSVAVMTSS 120

Query: 121 TSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGGLYQIPPQPRRAAPTTPPPPVK 180
           TSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGGLYQIPPQPRRAAPTTPPPPVK
Sbjct: 121 TSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGGLYQIPPQPRRAAPTTPPPPVK 180

Query: 181 RRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSSSPSEPGSSCSPTPPPVP 240
           RRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSSSPSEPGSSCSPTPPPVP
Sbjct: 181 RRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSSSPSEPGSSCSPTPPPVP 240

Query: 241 RRGTHTTVSQVQPPPSKASAPEPPAEEEVATGTTSASDDLEALGTLSLGTTEEKAAAEAA 300
           RRGTHTTVSQVQPPPSKASAPEPPAEEEVATGTTSASDDLEALGTLSLGTTEEKAAAEAA
Sbjct: 241 RRGTHTTVSQVQPPPSKASAPEPPAEEEVATGTTSASDDLEALGTLSLGTTEEKAAAEAA 300

Query: 301 VPRTIGAELMELVRRNTGLSHELCRVAIGIIVGHIQASVPASSPVMEQVLLSLVEGKDLS 360
           VPRTIGAELMELVRRNTGLSHELCRVAIGIIVGHIQASVPASSPVMEQVLLSLVEGKDLS
Sbjct: 301 VPRTIGAELMELVRRNTGLSHELCRVAIGIIVGHIQASVPASSPVMEQVLLSLVEGKDLS 360

Query: 361 MALPSGQVCHDQQRLEVIFADLARRKDDAQQRSWALYEDEGVIRCYLEELLHILTDADPE 420
           MALPSGQVCHDQQRLEVIFADLARRKDDAQQRSWALYEDEGVIRCYLEELLHILTDADPE
Sbjct: 361 MALPSGQVCHDQQRLEVIFADLARRKDDAQQRSWALYEDEGVIRCYLEELLHILTDADPE 420

Query: 421 VCKKMCKRNEFESVLALVAYYQMEHRASLRLLLLKCFGAMCSLDAAIISTLVSSVLPVEL 480
           VCKKMCKRNEFESVLALVAYYQMEHRASLRLLLLKCFGAMCSLDAAIISTLVSSVLPVEL
Sbjct: 421 VCKKMCKRNEFESVLALVAYYQMEHRASLRLLLLKCFGAMCSLDAAIISTLVSSVLPVEL 480

Query: 481 ARDMQTDTQDHQKLCYSALILAMVFSMGEAVPYAHYEHLGTPFAQFLLNIVEDGLPLDTT 540
           ARDMQTDTQDHQKLCYSALILAMVFSMGEAVPYAHYEHLGTPFAQFLLNIVEDGLPLDTT
Sbjct: 481 ARDMQTDTQDHQKLCYSALILAMVFSMGEAVPYAHYEHLGTPFAQFLLNIVEDGLPLDTT 540

Query: 541 EQLPDLCVNLLLALNLHLPAADQNVIMAALSKHANVKIFSEKLLLLLNRGDDPVRIFKHE 600
           EQLPDLCVNLLLALNLHLPAADQNVIMAALSKHANVKIFSEKLLLLLNRGDDPVRIFKHE
Sbjct: 541 EQLPDLCVNLLLALNLHLPAADQNVIMAALSKHANVKIFSEKLLLLLNRGDDPVRIFKHE 600

Query: 601 PQPPHSVLKFLQDVFGSPATAAIFYHTDMMALIDITVRHIADLSPGDKLRMEYLSLMHAI 660
           PQPPHSVLKFLQDVFGSPATAAIFYHTDMMALIDITVRHIADLSPGDKLRMEYLSLMHAI
Sbjct: 601 PQPPHSVLKFLQDVFGSPATAAIFYHTDMMALIDITVRHIADLSPGDKLRMEYLSLMHAI 660

Query: 661 VRTTPYLQHRHRLPDLQAILRRILNEEETSPQCQMDRMIVREMCKEFLVLGEAPS 715
           VRTTPYLQHRHRLPDLQAILRRILNEEETSPQCQMDRMIVREMCKEFLVLGEAPS
Sbjct: 661 VRTTPYLQHRHRLPDLQAILRRILNEEETSPQCQMDRMIVREMCKEFLVLGEAPS 715


>gi|7705266 NCK interacting protein with SH3 domain isoform 1 [Homo
           sapiens]
          Length = 722

 Score = 1409 bits (3647), Expect = 0.0
 Identities = 715/722 (99%), Positives = 715/722 (99%), Gaps = 7/722 (0%)

Query: 1   MYRALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGETGYVPPAYLRRLQGLE 60
           MYRALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGETGYVPPAYLRRLQGLE
Sbjct: 1   MYRALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGETGYVPPAYLRRLQGLE 60

Query: 61  QDVLQAIDRAIEAVHNTAMRDGGKYSLEQRGVLQKLIHHRKETLSRRGPSASSVAVMTSS 120
           QDVLQAIDRAIEAVHNTAMRDGGKYSLEQRGVLQKLIHHRKETLSRRGPSASSVAVMTSS
Sbjct: 61  QDVLQAIDRAIEAVHNTAMRDGGKYSLEQRGVLQKLIHHRKETLSRRGPSASSVAVMTSS 120

Query: 121 TSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGGLYQIP-------PQPRRAAPT 173
           TSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGGLYQIP       PQPRRAAPT
Sbjct: 121 TSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGGLYQIPLPSSQIPPQPRRAAPT 180

Query: 174 TPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSSSPSEPGSSCS 233
           TPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSSSPSEPGSSCS
Sbjct: 181 TPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSSSPSEPGSSCS 240

Query: 234 PTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGTTSASDDLEALGTLSLGTTEE 293
           PTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGTTSASDDLEALGTLSLGTTEE
Sbjct: 241 PTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGTTSASDDLEALGTLSLGTTEE 300

Query: 294 KAAAEAAVPRTIGAELMELVRRNTGLSHELCRVAIGIIVGHIQASVPASSPVMEQVLLSL 353
           KAAAEAAVPRTIGAELMELVRRNTGLSHELCRVAIGIIVGHIQASVPASSPVMEQVLLSL
Sbjct: 301 KAAAEAAVPRTIGAELMELVRRNTGLSHELCRVAIGIIVGHIQASVPASSPVMEQVLLSL 360

Query: 354 VEGKDLSMALPSGQVCHDQQRLEVIFADLARRKDDAQQRSWALYEDEGVIRCYLEELLHI 413
           VEGKDLSMALPSGQVCHDQQRLEVIFADLARRKDDAQQRSWALYEDEGVIRCYLEELLHI
Sbjct: 361 VEGKDLSMALPSGQVCHDQQRLEVIFADLARRKDDAQQRSWALYEDEGVIRCYLEELLHI 420

Query: 414 LTDADPEVCKKMCKRNEFESVLALVAYYQMEHRASLRLLLLKCFGAMCSLDAAIISTLVS 473
           LTDADPEVCKKMCKRNEFESVLALVAYYQMEHRASLRLLLLKCFGAMCSLDAAIISTLVS
Sbjct: 421 LTDADPEVCKKMCKRNEFESVLALVAYYQMEHRASLRLLLLKCFGAMCSLDAAIISTLVS 480

Query: 474 SVLPVELARDMQTDTQDHQKLCYSALILAMVFSMGEAVPYAHYEHLGTPFAQFLLNIVED 533
           SVLPVELARDMQTDTQDHQKLCYSALILAMVFSMGEAVPYAHYEHLGTPFAQFLLNIVED
Sbjct: 481 SVLPVELARDMQTDTQDHQKLCYSALILAMVFSMGEAVPYAHYEHLGTPFAQFLLNIVED 540

Query: 534 GLPLDTTEQLPDLCVNLLLALNLHLPAADQNVIMAALSKHANVKIFSEKLLLLLNRGDDP 593
           GLPLDTTEQLPDLCVNLLLALNLHLPAADQNVIMAALSKHANVKIFSEKLLLLLNRGDDP
Sbjct: 541 GLPLDTTEQLPDLCVNLLLALNLHLPAADQNVIMAALSKHANVKIFSEKLLLLLNRGDDP 600

Query: 594 VRIFKHEPQPPHSVLKFLQDVFGSPATAAIFYHTDMMALIDITVRHIADLSPGDKLRMEY 653
           VRIFKHEPQPPHSVLKFLQDVFGSPATAAIFYHTDMMALIDITVRHIADLSPGDKLRMEY
Sbjct: 601 VRIFKHEPQPPHSVLKFLQDVFGSPATAAIFYHTDMMALIDITVRHIADLSPGDKLRMEY 660

Query: 654 LSLMHAIVRTTPYLQHRHRLPDLQAILRRILNEEETSPQCQMDRMIVREMCKEFLVLGEA 713
           LSLMHAIVRTTPYLQHRHRLPDLQAILRRILNEEETSPQCQMDRMIVREMCKEFLVLGEA
Sbjct: 661 LSLMHAIVRTTPYLQHRHRLPDLQAILRRILNEEETSPQCQMDRMIVREMCKEFLVLGEA 720

Query: 714 PS 715
           PS
Sbjct: 721 PS 722


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 59/205 (28%), Positives = 86/205 (41%), Gaps = 33/205 (16%)

Query: 106  RRGPSASSVAVMTSSTSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGGLYQIP- 164
            RR  S+SS +  +SS+S     ++++        +G     S  SS  +  +  L ++P 
Sbjct: 2530 RRSSSSSSSSSSSSSSSSSSSSSSSS--------SGSSSSDSEGSSLPVQPEVALKRVPS 2581

Query: 165  --PQPRRAAPTTPPP---PVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTL 219
              P P+ A     PP   P KR+ R +  +S S       S  +S SS SS SS+S  + 
Sbjct: 2582 PTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSS-------SSSSSSSSSSSSSSSSSSSS 2634

Query: 220  YTSSSPSEPGSSCSPTP-PPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGTTSASD 278
             +SSS S   SS SP+P  P P           Q  P  AS  +PP  E  +       D
Sbjct: 2635 SSSSSSSSSSSSSSPSPAKPGP-----------QALPKPASPKKPPPGERRSRSPRKPID 2683

Query: 279  DLEALGTLSLGTTEEKAAAEAAVPR 303
             L    +LS    E +  +    PR
Sbjct: 2684 SLRDSRSLSYSPVERRRPSPQPSPR 2708



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 47/202 (23%), Positives = 76/202 (37%), Gaps = 28/202 (13%)

Query: 99  HRKETLSRRGPSASSVAVMTSSTSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADG 158
           HR  +      S +S +   S+ +  H  A A R P+    +G   +   P SE  G   
Sbjct: 261 HRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPA--SGRRGEGDAPFSEP-GTTS 317

Query: 159 GLYQIPPQPRRAAPTTP--PPPVKRRDREALMASGSGGHNTM----PSGGNSVSSGSSVS 212
                 P+     P++P       ++++ A   S S   ++     P+    ++     S
Sbjct: 318 TQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGS 377

Query: 213 STSLDTLYTSSSPSEPGSSCSPT----PPPVPRRGTHTTVSQVQPP---PSKAS------ 259
              L T   S  P  P S  SPT    PP  P +   ++ S+  PP   P+K S      
Sbjct: 378 PQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSS 437

Query: 260 ------APEPPAEEEVATGTTS 275
                 AP P +  E+++  TS
Sbjct: 438 PESPKPAPAPGSHREISSSPTS 459



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 46/196 (23%), Positives = 79/196 (40%), Gaps = 33/196 (16%)

Query: 110  SASSVAVMTSSTSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGGLYQIPPQPRR 169
            S+ +VA  TSS  DH          NG+         S+P+     +D G    PP    
Sbjct: 2476 SSGAVATTTSSAGDH----------NGML--------SVPAPGVPHSDVGE---PPASTG 2514

Query: 170  A----APTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSSSP 225
            A    A     P  +RR   +  +S S   ++  S  +S SSGSS S +       SS P
Sbjct: 2515 AQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSE-----GSSLP 2569

Query: 226  SEPGSSCSPTPPPVPRRGTHTTVSQVQPP-PSKASAPEPPAEEEVATGTTSASDDLEALG 284
             +P  +    P P P       V + +PP P+ A      +    ++ ++S+S    +  
Sbjct: 2570 VQPEVALKRVPSPTP--APKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSS 2627

Query: 285  TLSLGTTEEKAAAEAA 300
            + S  ++   +++ ++
Sbjct: 2628 SSSSSSSSSSSSSSSS 2643



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 45/184 (24%), Positives = 65/184 (35%), Gaps = 12/184 (6%)

Query: 100 RKETLSRRGPSASSVAVMTSSTSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGG 159
           R  T +RRG S S      S  S     A   R  +   R G  R  SL         G 
Sbjct: 659 RSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRR------GR 712

Query: 160 LYQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGH----NTMPSGGNSVSSGSSVSSTS 215
            +   PQ R  + ++     K R  +    S S               S+SS  S + + 
Sbjct: 713 SHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSR 772

Query: 216 LDTLYTSSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPP--SKASAPEPPAEEEVATGT 273
           L    + S  S      S TPP   R G+    ++ + PP  S++S+  PP ++      
Sbjct: 773 LSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSR 832

Query: 274 TSAS 277
            S S
Sbjct: 833 QSHS 836



 Score = 34.3 bits (77), Expect = 0.41
 Identities = 39/180 (21%), Positives = 67/180 (37%), Gaps = 10/180 (5%)

Query: 109  PSASSVAVMTSSTSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGGLYQIPPQ-- 166
            PSA ++A   + T+   ++ A AR P  +         + P++ +  +     Q P    
Sbjct: 2279 PSAVNLADPRTPTAPA-VNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASAN 2337

Query: 167  ---PRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSS 223
               PR A  T P      R   AL  +        P+   +  +   V  ++ + +   +
Sbjct: 2338 LVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRT 2397

Query: 224  SPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPE----PPAEEEVATGTTSASDD 279
            SP     + S TPP  P +   T+     P      AP     PPA+++  +   SA  D
Sbjct: 2398 SPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSD 2457



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 42/169 (24%), Positives = 58/169 (34%), Gaps = 17/169 (10%)

Query: 100 RKETLSRRGPSASSVAVMTSSTSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGG 159
           + +T  RR  S SS     S T      ++++  P    +    + HS  SS H     G
Sbjct: 789 KSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHS-SSSPHPKVKSG 847

Query: 160 L--------------YQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSV 205
                            + PQ R    ++P P +K R       SGS       S     
Sbjct: 848 TPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQ 907

Query: 206 S-SGSSVSSTSLDTLYTSSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQP 253
           S S SS     +  + +    S  GSS SP+P  V  R T      V P
Sbjct: 908 SPSRSSSPQPKVKAIISPRQRSHSGSS-SPSPSRVTSRTTPRRSRSVSP 955



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 30/127 (23%), Positives = 49/127 (38%), Gaps = 23/127 (18%)

Query: 167 PRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVS-------------- 212
           PRR+  ++ PPP ++    +  +  S   +     G     GS  S              
Sbjct: 812 PRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRS 871

Query: 213 --STSLDTLYTSSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVA 270
              +S D    S +PS    SCS + PP  +  T    S     PS++S+P+P  +  ++
Sbjct: 872 CFESSPDPELKSRTPSR--HSCSGSSPPRVKSSTPPRQS-----PSRSSSPQPKVKAIIS 924

Query: 271 TGTTSAS 277
               S S
Sbjct: 925 PRQRSHS 931



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 33/109 (30%), Positives = 46/109 (42%), Gaps = 15/109 (13%)

Query: 164  PPQPRRAAPTTPPPPVK-----RRDREALMASGSGGH---NTMPSGGNSVSSGSSVSSTS 215
            PP+   +  ++P P VK     R+   +  +S S       T P    SVS  S+V S  
Sbjct: 904  PPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRL 963

Query: 216  LDTLYTSSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEPP 264
            L   Y+ S  S P +   P  PP   R +H+    + P P K  A  PP
Sbjct: 964  LPR-YSHSGSSSPDTKVKPETPP---RQSHS--GSISPYP-KVKAQTPP 1005


>gi|23510364 protein-tyrosine kinase fyn isoform c [Homo sapiens]
          Length = 482

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 20/62 (32%), Positives = 34/62 (54%)

Query: 1   MYRALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGETGYVPPAYLRRLQGLE 60
           ++ ALY + +   + L+F  GE F +L  S   WW A    +GETGY+P  Y+  +  ++
Sbjct: 86  LFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSIQ 145

Query: 61  QD 62
            +
Sbjct: 146 AE 147


>gi|23510362 protein-tyrosine kinase fyn isoform b [Homo sapiens]
          Length = 534

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 20/62 (32%), Positives = 34/62 (54%)

Query: 1   MYRALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGETGYVPPAYLRRLQGLE 60
           ++ ALY + +   + L+F  GE F +L  S   WW A    +GETGY+P  Y+  +  ++
Sbjct: 86  LFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSIQ 145

Query: 61  QD 62
            +
Sbjct: 146 AE 147


>gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens]
          Length = 537

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 20/62 (32%), Positives = 34/62 (54%)

Query: 1   MYRALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGETGYVPPAYLRRLQGLE 60
           ++ ALY + +   + L+F  GE F +L  S   WW A    +GETGY+P  Y+  +  ++
Sbjct: 86  LFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSIQ 145

Query: 61  QD 62
            +
Sbjct: 146 AE 147


>gi|130977759 tec protein tyrosine kinase [Homo sapiens]
          Length = 631

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 20/50 (40%), Positives = 32/50 (64%), Gaps = 1/50 (2%)

Query: 4   ALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGETGYVPPAYL 53
           A+Y F++AE + L    G+ +L+LE++  HWW  AR + G  GY+P  Y+
Sbjct: 186 AMYDFQAAEGHDLRLERGQEYLILEKNDVHWW-RARDKYGNEGYIPSNYV 234


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 41/144 (28%), Positives = 52/144 (36%), Gaps = 7/144 (4%)

Query: 165 PQPRRAAPTT--PPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTS 222
           P PRR  P    PPPP  RR R  +        +   SG +S SS S   S        +
Sbjct: 321 PSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASL--SGSSSSSSSSRSRSPPKKPPKRT 378

Query: 223 SSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGTTSASDD-LE 281
           SSP       SP+  P  RR  H       PPP    +P P           S S     
Sbjct: 379 SSPPRKTRRLSPSASPPRRR--HRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTS 436

Query: 282 ALGTLSLGTTEEKAAAEAAVPRTI 305
              T   GT + ++ + A  PR +
Sbjct: 437 GKVTKHKGTEKRESPSPAPKPRKV 460



 Score = 39.3 bits (90), Expect = 0.013
 Identities = 47/202 (23%), Positives = 76/202 (37%), Gaps = 15/202 (7%)

Query: 106 RRGPSASSVAVMTSSTSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGGLYQIPP 165
           R+   +SS +  +SS+ D     +  +  NG    G  R+HS   S          +  P
Sbjct: 487 RQNQQSSSDSGSSSSSEDERPKRSHVK--NG--EVGRRRRHSPSRSASPSPRKRQKETSP 542

Query: 166 QPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTS----LDTLYT 221
           + RR    +PPP  +RR              T P    + S      S S       +  
Sbjct: 543 RGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQR 602

Query: 222 SSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGTTSASDDLE 281
             SPS P    + +PPP P+R      +   PPP +  +  PP ++  +  T   S  L 
Sbjct: 603 RYSPSPPPKRRTASPPPPPKRR-----ASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLS 657

Query: 282 ALGTLSLGTTEEKAAAEAAVPR 303
           +      G++  ++  EA  P+
Sbjct: 658 S--KHRKGSSPSRSTREARSPQ 677



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 50/181 (27%), Positives = 69/181 (38%), Gaps = 38/181 (20%)

Query: 106 RRGPSASSVAVMTSSTSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGGLYQIPP 165
           RR PS SS     SS S    +A +  QPN        ++HS PS              P
Sbjct: 651 RRSPSLSSKHRKGSSPSRSTREARSP-QPN--------KRHS-PS--------------P 686

Query: 166 QPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNS-------VSSGSSVSSTSLDT 218
           +PR    ++ PPPV+R    +     S   +T P    S       +   +S S  S+  
Sbjct: 687 RPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRR 746

Query: 219 LYTSSSPS---EPGSSCSPTPP-PVPRRGTHTTVSQVQP---PPSKASAPEPPAEEEVAT 271
           + +S S S   EP +   P PP PV  +   T  S   P     S   +P PP   +   
Sbjct: 747 VSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEG 806

Query: 272 G 272
           G
Sbjct: 807 G 807



 Score = 35.0 bits (79), Expect = 0.24
 Identities = 42/173 (24%), Positives = 69/173 (39%), Gaps = 27/173 (15%)

Query: 161 YQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGN---------SVSS---- 207
           Y   P P+R   + PPPP KRR   +        H+  P   +         S+SS    
Sbjct: 604 YSPSPPPKRRTASPPPPP-KRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRK 662

Query: 208 GSSVSSTSLDTLYT------SSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSK---- 257
           GSS S ++ +          S SP       S +PPPV R  + +   +  P PS     
Sbjct: 663 GSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIR 722

Query: 258 --ASAPEPPAEEEVATGTTSASDDLEALGTLSLGTTEEKAAAEAAVPRTIGAE 308
             +  PEP   ++ A+ +  +   + +  ++S G+ E  A    A P  + ++
Sbjct: 723 RVSRTPEPKKIKKAASPSPQSVRRVSSSRSVS-GSPEPAAKKPPAPPSPVQSQ 774


>gi|15718680 IL2-inducible T-cell kinase [Homo sapiens]
          Length = 620

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 20/50 (40%), Positives = 30/50 (60%), Gaps = 1/50 (2%)

Query: 4   ALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGETGYVPPAYL 53
           ALY +++ +P  LA    E + +L+ S  HWW   + R+G  GYVP +YL
Sbjct: 178 ALYDYQTNDPQELALRRNEEYCLLDSSEIHWW-RVQDRNGHEGYVPSSYL 226


>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
          Length = 953

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 39/130 (30%), Positives = 54/130 (41%), Gaps = 21/130 (16%)

Query: 167 PRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVS-STSLDTLYTSSSP 225
           P++    +  P   RR R+   +S S  +++  S  +S  SGS  S S S  + Y+S S 
Sbjct: 525 PKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSS 584

Query: 226 SEP---------------GSSCSPTPPPVPRRGTHTTVSQVQPPPSKA-----SAPEPPA 265
                              SS SP+P P P R +  T  +  PPP KA       P PP 
Sbjct: 585 RSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPP 644

Query: 266 EEEVATGTTS 275
               AT TT+
Sbjct: 645 APPQATKTTA 654



 Score = 34.7 bits (78), Expect = 0.32
 Identities = 39/137 (28%), Positives = 55/137 (40%), Gaps = 32/137 (23%)

Query: 164 PPQPRRAAPTTPPPP----------VKRRDREA--------LMASGSGGHNTMPSGGNSV 205
           PP P +A  TT P P           +R++R A        L  SGSG  ++  SG +S 
Sbjct: 643 PPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSY-SGSSSR 701

Query: 206 SSGSSVSSTSLDTLYTSSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEP-P 264
           S   SVSS S  +  TSSS S                 +    + +  P S AS+  P P
Sbjct: 702 SRSLSVSSVSSVSSATSSSSSAHSVD------------SEDMYADLASPVSSASSRSPAP 749

Query: 265 AEEEVATGTTSASDDLE 281
           A+     G +   D ++
Sbjct: 750 AQTRKEKGKSKKEDGVK 766



 Score = 31.6 bits (70), Expect = 2.7
 Identities = 26/98 (26%), Positives = 34/98 (34%), Gaps = 10/98 (10%)

Query: 190 SGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSSSPSEPGSSCS------PTPPPVPRRG 243
           S   G  +     +S  S S   S    ++ T   P+ P           P PPP P + 
Sbjct: 590 SSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQA 649

Query: 244 THTTVSQVQP----PPSKASAPEPPAEEEVATGTTSAS 277
           T TT    +P     P +A   E PA       T S S
Sbjct: 650 TKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGS 687


>gi|38683860 insulin receptor substrate 2 [Homo sapiens]
          Length = 1338

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 78/347 (22%), Positives = 119/347 (34%), Gaps = 73/347 (21%)

Query: 56   LQGLEQDVLQAIDRAIEAVHNTAMRDGGKYSLEQRGVLQKLIHHRKETLSRRGPSASSVA 115
            L+G+      ++ R+ +A + T   D  +Y L    V + L   R E  +  GPS ++ A
Sbjct: 795  LRGVPGCCYSSLPRSYKAPY-TCGGDSDQYVLMSSPVGRILEEERLEPQATPGPSQAASA 853

Query: 116  VMTSSTSDHHLDAAAARQPNGVCRAGFERQH---------------SLPSSEHLGADGGL 160
                 T   H    +  +P+G    GF  Q                SLPS          
Sbjct: 854  FGAGPTQPPHPVVPSPVRPSGGRPEGFLGQRGRAVRPTRLSLEGLPSLPSMHE------- 906

Query: 161  YQIPPQPRR------------AAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSG 208
            Y +PP+P+              A  +PP P        L+AS +   + + +   + S G
Sbjct: 907  YPLPPEPKSPGEYINIDFGEPGARLSPPAP-------PLLASAASSSSLLSASSPASSLG 959

Query: 209  SSVSSTSLDTLYTS----------SSPSEP--------------------GSSCSPTPPP 238
            S    TS D+   S          SSP  P                     SS  P  PP
Sbjct: 960  SGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPEASSPYPPLPP 1019

Query: 239  VPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGTTSASDDLEALGTLSLGTTEEKAAAE 298
             P     +++    PPP+       P    VAT     +    +  T   G   E A   
Sbjct: 1020 RPSASPSSSLQPPPPPPAPGELYRLPPASAVATAQGPGAASSLSSDTGDNGDYTEMAFGV 1079

Query: 299  AAV-PRTIGAELMELVRRNTGLSHELCRVAIGIIVGHIQASVPASSP 344
            AA  P+ I A       R    +  + R+++   V  ++A + AS P
Sbjct: 1080 AATPPQPIAAPPKPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQP 1126


>gi|148596974 TXK tyrosine kinase [Homo sapiens]
          Length = 527

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 22/51 (43%), Positives = 29/51 (56%), Gaps = 1/51 (1%)

Query: 3   RALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGETGYVPPAYL 53
           +ALY F   EP  LA    E +L+LE+ + HWW  AR R G  G +P  Y+
Sbjct: 88  KALYDFLPREPCNLALRRAEEYLILEKYNPHWW-KARDRLGNEGLIPSNYV 137


>gi|38202217 proto-oncogene tyrosine-protein kinase SRC [Homo
           sapiens]
          Length = 536

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 18/50 (36%), Positives = 27/50 (54%)

Query: 4   ALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGETGYVPPAYL 53
           ALY + S     L+F  GE   ++  +   WWLA    +G+TGY+P  Y+
Sbjct: 91  ALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYV 140


>gi|4885609 proto-oncogene tyrosine-protein kinase SRC [Homo
           sapiens]
          Length = 536

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 18/50 (36%), Positives = 27/50 (54%)

Query: 4   ALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGETGYVPPAYL 53
           ALY + S     L+F  GE   ++  +   WWLA    +G+TGY+P  Y+
Sbjct: 91  ALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYV 140


>gi|161169015 neuron navigator 2 isoform 3 [Homo sapiens]
          Length = 2365

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 33/111 (29%), Positives = 50/111 (45%), Gaps = 5/111 (4%)

Query: 173 TTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSSSPSEPGSSC 232
           T+PPPP    ++E L +S S       +   S+ SGSS + T+     TSS+  +PG++ 
Sbjct: 235 TSPPPPPSSHEKEPLASSASSHPGMSDNAPASLESGSSSTPTNCS---TSSAIPQPGAAT 291

Query: 233 SPTPPPVPRRGTHTTVS--QVQPPPSKASAPEPPAEEEVATGTTSASDDLE 281
            P            TVS   V+PP  +A  P P A +       S  + L+
Sbjct: 292 KPWRSKSLSVKHSATVSMLSVKPPGPEAPRPTPEAMKPAPNNQKSMLEKLK 342


>gi|161169013 neuron navigator 2 isoform 1 [Homo sapiens]
          Length = 2432

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 33/111 (29%), Positives = 50/111 (45%), Gaps = 5/111 (4%)

Query: 173 TTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSSSPSEPGSSC 232
           T+PPPP    ++E L +S S       +   S+ SGSS + T+     TSS+  +PG++ 
Sbjct: 299 TSPPPPPSSHEKEPLASSASSHPGMSDNAPASLESGSSSTPTNCS---TSSAIPQPGAAT 355

Query: 233 SPTPPPVPRRGTHTTVS--QVQPPPSKASAPEPPAEEEVATGTTSASDDLE 281
            P            TVS   V+PP  +A  P P A +       S  + L+
Sbjct: 356 KPWRSKSLSVKHSATVSMLSVKPPGPEAPRPTPEAMKPAPNNQKSMLEKLK 406


>gi|38044282 neuron navigator 2 isoform 2 [Homo sapiens]
          Length = 2429

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 33/111 (29%), Positives = 50/111 (45%), Gaps = 5/111 (4%)

Query: 173 TTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSSSPSEPGSSC 232
           T+PPPP    ++E L +S S       +   S+ SGSS + T+     TSS+  +PG++ 
Sbjct: 299 TSPPPPPSSHEKEPLASSASSHPGMSDNAPASLESGSSSTPTNCS---TSSAIPQPGAAT 355

Query: 233 SPTPPPVPRRGTHTTVS--QVQPPPSKASAPEPPAEEEVATGTTSASDDLE 281
            P            TVS   V+PP  +A  P P A +       S  + L+
Sbjct: 356 KPWRSKSLSVKHSATVSMLSVKPPGPEAPRPTPEAMKPAPNNQKSMLEKLK 406


>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
           sapiens]
          Length = 505

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 31/110 (28%), Positives = 38/110 (34%), Gaps = 9/110 (8%)

Query: 164 PPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSS--------GSSVSSTS 215
           PP P R  P  PPPP          A G G     PS   + +           +V    
Sbjct: 279 PPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPP 338

Query: 216 LDTLYTSSSPSEPGSSCSPTPPPVPR-RGTHTTVSQVQPPPSKASAPEPP 264
            + +Y    P+ P S+ S  PPP P   G         PPP     P PP
Sbjct: 339 PNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPP 388


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 35/141 (24%), Positives = 54/141 (38%), Gaps = 7/141 (4%)

Query: 167 PRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSSSPS 226
           PR A    P PP +   +    AS        P+     S+G  +   +  +L +S++P 
Sbjct: 190 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 249

Query: 227 EPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGTTSASDDLEALGTL 286
              +   P+    PR   H +    QP P    A  PP   +V      A+  L  L + 
Sbjct: 250 SSPARSGPSARGTPRAPAHPS----QPKPKGLQALRPP---QVTPPRKDAAPALGPLSSS 302

Query: 287 SLGTTEEKAAAEAAVPRTIGA 307
            L T    AA ++  P T+ A
Sbjct: 303 PLATPSPSAALQSQAPPTLPA 323



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 28/111 (25%), Positives = 42/111 (37%), Gaps = 16/111 (14%)

Query: 167 PRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSSSPS 226
           PR      PPPPV       L A+G+ G   +      +   +   S         + P+
Sbjct: 27  PRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESA------PRAGPT 80

Query: 227 EPGSSCSPTP---PPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGTT 274
               + S  P   PP   RG        + PP+K ++P P +    A+GTT
Sbjct: 81  RSAGTSSRNPASRPPASGRGE-------RAPPAKNTSPGPVSSPGRASGTT 124



 Score = 33.1 bits (74), Expect = 0.92
 Identities = 40/140 (28%), Positives = 47/140 (33%), Gaps = 25/140 (17%)

Query: 165 PQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSSS 224
           P+   A    PPPP  R     L      GH+            SS +ST  +     S 
Sbjct: 601 PRLTLALAPGPPPPPSRSPSSTLSGPDLAGHS------------SSATSTPEELRGYDSG 648

Query: 225 PSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKA--SAPEPPAEEEVATGTTSASDDLEA 282
           P E G++ SP PP       H       P P  A   AP  P     ATG  SA      
Sbjct: 649 P-EGGAAASP-PPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSAD----- 701

Query: 283 LGTLSLGTTEEKAAAEAAVP 302
                L T  E    E+A P
Sbjct: 702 ----GLCTIYETEGPESATP 717



 Score = 31.2 bits (69), Expect = 3.5
 Identities = 33/148 (22%), Positives = 46/148 (31%), Gaps = 31/148 (20%)

Query: 149 PSSEHLGADGGLYQIPPQPRRAAPTT------------PP--------PPVKRRDREALM 188
           P +E  G  GG   IP    RA PT             PP        PP K      + 
Sbjct: 57  PLAERAGGIGGA-TIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVS 115

Query: 189 ASGSGGHNTMP----------SGGNSVSSGSSVSSTSLDTLYTSSSPSEPGSSCSPTPPP 238
           + G     T P          S   +V+ G +  +     L   +     G +     P 
Sbjct: 116 SPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPA 175

Query: 239 VPRRGTHTTVSQVQPPPSKASAPEPPAE 266
           + RR          P P+ ++ P PP E
Sbjct: 176 MARRSRAAGTEVGLPRPAPSARPRPPTE 203



 Score = 30.4 bits (67), Expect = 6.0
 Identities = 44/191 (23%), Positives = 64/191 (33%), Gaps = 23/191 (12%)

Query: 105 SRRGPSASSVAVMTSSTSDHHL---DAAAARQPNGVCRAGFERQHSLPSSEHLGADGGLY 161
           +R  P         SS S+H       AA R+P+     G +R    P+S  L +     
Sbjct: 196 ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA--GGGLQR----PASRSLSSSATPL 249

Query: 162 QIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYT 221
             P +   +A  TP  P      +             P   ++  +   +SS+ L T   
Sbjct: 250 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT--- 306

Query: 222 SSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQP----------PPSKASAPEPPAEEEVAT 271
             SPS    S +P   P     +  T     P          PPS  + P PPA      
Sbjct: 307 -PSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQA 365

Query: 272 GTTSASDDLEA 282
            T+  S  L+A
Sbjct: 366 TTSLGSPTLQA 376



 Score = 30.4 bits (67), Expect = 6.0
 Identities = 30/110 (27%), Positives = 40/110 (36%), Gaps = 29/110 (26%)

Query: 164 PPQPRRAAPTTPP--PPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYT 221
           PP P   AP +PP  PPV                   PS      +  S+++  L     
Sbjct: 443 PPSPPVQAPFSPPASPPVS------------------PSATPPSQAPPSLAAPPLQV--P 482

Query: 222 SSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVAT 271
            S P+ P  S S TPPP            +  PP + + P P A   +AT
Sbjct: 483 PSPPASPPMSPSATPPP-------QAPPPLAAPPLQLAKPPPQAPPALAT 525



 Score = 30.4 bits (67), Expect = 6.0
 Identities = 22/69 (31%), Positives = 29/69 (42%), Gaps = 2/69 (2%)

Query: 225 PSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGTTSASDDLEALG 284
           PS P S     P   P  G  T+VS   P  + A AP PP     +  +T +  DL    
Sbjct: 575 PSPPASPTLQAPRRPPTPGPDTSVS--GPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHS 632

Query: 285 TLSLGTTEE 293
           + +  T EE
Sbjct: 633 SSATSTPEE 641


>gi|20143482 melanoma antigen family E, 1 [Homo sapiens]
          Length = 957

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 55/219 (25%), Positives = 86/219 (39%), Gaps = 17/219 (7%)

Query: 102 ETLSRRGPSASSVAVMTSSTSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGGLY 161
           E LS  GP   S  + TS T    L A+  R  +    +  E   S+P +    ++    
Sbjct: 110 EGLSTSGPPTISKGLCTSVT----LAASEGRNTSRPPTSSEEPSTSVPPT---ASEVPST 162

Query: 162 QIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNT--MPSGGNSVSSGSSVSSTSLDTL 219
            +PP P     T+ PP        +++ +   G +T  +P+ G     G+SV   + + L
Sbjct: 163 SLPPTPGEGTSTSVPPTAYEGPSTSVVPTPDEGPSTSVLPTPGEG--PGTSVPLAATEGL 220

Query: 220 YTSSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGTTSASDD 279
            TS   + P    S + PP    G  T V   +      S P  P E    +   +ASD 
Sbjct: 221 STSVQAT-PDEGPSTSVPPTATEGLSTPVPPTRDEGPSTSVPATPGEGPSTSVLPAASDG 279

Query: 280 LEALGTLSLGTTEEKAAAEAAVPRTIGAELMELVRRNTG 318
                ++SL  T  K ++  +VP T    L   V+   G
Sbjct: 280 ----QSISLVPTRGKGSS-TSVPPTATEGLSTSVQPTAG 313



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 38/149 (25%), Positives = 57/149 (38%), Gaps = 6/149 (4%)

Query: 156 ADGGLYQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTS 215
           ++G    + P P     T+ PP + +    ++  + S G NT     +S    +SV  T+
Sbjct: 97  SEGPGTSVLPTPSEGLSTSGPPTISKGLCTSVTLAASEGRNTSRPPTSSEEPSTSVPPTA 156

Query: 216 LDTLYTSSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGTTS 275
            +   TS  P+ PG   S + PP    G  T+V          S    P E     GT+ 
Sbjct: 157 SEVPSTSLPPT-PGEGTSTSVPPTAYEGPSTSVVPTPDEGPSTSVLPTPGE---GPGTSV 212

Query: 276 ASDDLEALGTLSLGTTEEKAAAEAAVPRT 304
                E L T    T +E      +VP T
Sbjct: 213 PLAATEGLSTSVQATPDE--GPSTSVPPT 239



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 35/122 (28%), Positives = 53/122 (43%), Gaps = 7/122 (5%)

Query: 149 PSSEHLGA--DGGLYQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTM--PSGGNS 204
           PS+  L A  DG    + P   + + T+ PP        ++  +   G +T   P+ G  
Sbjct: 268 PSTSVLPAASDGQSISLVPTRGKGSSTSVPPTATEGLSTSVQPTAGEGSSTSVPPTPGGG 327

Query: 205 VSSGSSVSSTSLDTLYTSSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEPP 264
           +S+  SV  T+ + L TS  P+ PG   S +  P+P  G  T+V       S  S P  P
Sbjct: 328 LST--SVPPTATEELSTSVPPT-PGEGPSTSVLPIPGEGLSTSVPPTASDGSDTSVPPTP 384

Query: 265 AE 266
            E
Sbjct: 385 GE 386


>gi|112382244 proto-oncogene tyrosine-protein kinase FGR [Homo
           sapiens]
          Length = 529

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 18/62 (29%), Positives = 32/62 (51%)

Query: 1   MYRALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGETGYVPPAYLRRLQGLE 60
           ++ ALY + +   + L F  GE F +L  +   WW A    SG+TG +P  Y+  +  ++
Sbjct: 81  LFIALYDYEARTEDDLTFTKGEKFHILNNTEGDWWEARSLSSGKTGCIPSNYVAPVDSIQ 140

Query: 61  QD 62
            +
Sbjct: 141 AE 142


>gi|112382241 proto-oncogene tyrosine-protein kinase FGR [Homo
           sapiens]
          Length = 529

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 18/62 (29%), Positives = 32/62 (51%)

Query: 1   MYRALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGETGYVPPAYLRRLQGLE 60
           ++ ALY + +   + L F  GE F +L  +   WW A    SG+TG +P  Y+  +  ++
Sbjct: 81  LFIALYDYEARTEDDLTFTKGEKFHILNNTEGDWWEARSLSSGKTGCIPSNYVAPVDSIQ 140

Query: 61  QD 62
            +
Sbjct: 141 AE 142


>gi|4885235 proto-oncogene tyrosine-protein kinase FGR [Homo
           sapiens]
          Length = 529

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 18/62 (29%), Positives = 32/62 (51%)

Query: 1   MYRALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGETGYVPPAYLRRLQGLE 60
           ++ ALY + +   + L F  GE F +L  +   WW A    SG+TG +P  Y+  +  ++
Sbjct: 81  LFIALYDYEARTEDDLTFTKGEKFHILNNTEGDWWEARSLSSGKTGCIPSNYVAPVDSIQ 140

Query: 61  QD 62
            +
Sbjct: 141 AE 142


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 36/117 (30%), Positives = 48/117 (41%), Gaps = 21/117 (17%)

Query: 161 YQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLY 220
           +Q PP P+      PPPP +   +  ++A G G     P  G++  + SS       T  
Sbjct: 85  HQPPPHPQPHQQQQPPPPPQDSSKP-VVAQGPG---PAPGVGSAPPASSSAPPA---TPP 137

Query: 221 TSSSPSEPGSSCSPTPPPV-------------PRRGTHTTVSQV-QPPPSKASAPEP 263
           TS +P   G   +PTPPP              P  G  TT  Q   PPP  A+ P P
Sbjct: 138 TSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGP 194



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 25/86 (29%), Positives = 31/86 (36%), Gaps = 2/86 (2%)

Query: 182 RDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSSSPSEPGSSCSPTPPPVPR 241
           RDR      G GG +    GG         S      L  +  P  PG   S   PP+P 
Sbjct: 3   RDRFRSRGGGGGGFHRRGGGGGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPIPP 62

Query: 242 RGTHTTVSQVQPPPSKASAPEPPAEE 267
              H    Q QPPP +    +PP  +
Sbjct: 63  PPPHQ--QQQQPPPQQPPPQQPPPHQ 86


>gi|68348709 formin binding protein 1-like isoform 1 [Homo sapiens]
          Length = 551

 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 18/51 (35%), Positives = 26/51 (50%)

Query: 3   RALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGETGYVPPAYL 53
           +A+Y F       LA   GE   ++E      W  AR ++GE GYVP +Y+
Sbjct: 486 KAIYPFDGHNEGTLAMKEGEVLYIIEEDKGDGWTRARRQNGEEGYVPTSYI 536


>gi|41581463 formin binding protein 1-like isoform 2 [Homo sapiens]
          Length = 547

 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 18/51 (35%), Positives = 26/51 (50%)

Query: 3   RALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGETGYVPPAYL 53
           +A+Y F       LA   GE   ++E      W  AR ++GE GYVP +Y+
Sbjct: 486 KAIYPFDGHNEGTLAMKEGEVLYIIEEDKGDGWTRARRQNGEEGYVPTSYI 536


>gi|39930351 dynamin binding protein [Homo sapiens]
          Length = 1577

 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 21/61 (34%), Positives = 35/61 (57%), Gaps = 6/61 (9%)

Query: 1    MYRALYAFRSAEPNALAFAAGETFLVLE----RSSAHWWLAARARSGETGYVPPAYLRRL 56
            +Y A+Y F++  PN L+ +A +   +LE      +  WWLA    +G+ GYVP  Y+R+ 
Sbjct: 1517 VYFAVYTFKARNPNELSVSANQKLKILEFKDVTGNTEWWLA--EVNGKKGYVPSNYIRKT 1574

Query: 57   Q 57
            +
Sbjct: 1575 E 1575



 Score = 30.0 bits (66), Expect = 7.8
 Identities = 16/51 (31%), Positives = 24/51 (47%), Gaps = 2/51 (3%)

Query: 4   ALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGETGYVPPAYLR 54
           ALY F++ EPN L F  G+   +L      W     +  G TG  P  +++
Sbjct: 250 ALYRFQALEPNELDFEVGDKIRILATLEDGW--LEGSLKGRTGIFPYRFVK 298


>gi|20149528 proline-serine-threonine phosphatase interacting
           protein 1 [Homo sapiens]
          Length = 416

 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 20/55 (36%), Positives = 31/55 (56%), Gaps = 2/55 (3%)

Query: 2   YRALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGETGYVPPAYLRRL 56
           YRALY + +  P+ L  +AG+   V+      WW     R+G+ G+VP +YL +L
Sbjct: 364 YRALYDYTAQNPDELDLSAGDILEVILEGEDGWWTV--ERNGQRGFVPGSYLEKL 416


>gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo
           sapiens]
          Length = 870

 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 47/198 (23%), Positives = 76/198 (38%), Gaps = 8/198 (4%)

Query: 109 PSASSVAVMTSSTSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGGLYQIP-PQP 167
           P+++  A+   ++SD    A++   P G   A   R+ + P+    G  GGL   P P+ 
Sbjct: 598 PASAEEAIPLPASSDSERSASSVEGPGGALYARVARREARPARAR-GEIGGLSLSPSPER 656

Query: 168 RRAAPTTP--PPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLD-TLYTSSS 224
           R+  P  P   P V     +   A+     +  P G  +  S S    T  D + +T   
Sbjct: 657 RKPPPPDPATKPKVSWIHGKHSAAAAGRAPSPPPPGSEAAPSPSKRKRTPSDKSAHTVEH 716

Query: 225 PSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKA-SAPEPPAEEEVATGTTSASDDLEAL 283
            S      +P PP +P     T ++   PP ++A +AP P             ++    L
Sbjct: 717 GSPRTRDPTPRPPGLPEEA--TALAAPSPPRARARAAPRPLGAHGRRRSPAKRAEAASML 774

Query: 284 GTLSLGTTEEKAAAEAAV 301
                G T     AE A+
Sbjct: 775 AADVRGKTRSLGRAEVAL 792


>gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo
           sapiens]
          Length = 865

 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 47/198 (23%), Positives = 76/198 (38%), Gaps = 8/198 (4%)

Query: 109 PSASSVAVMTSSTSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGGLYQIP-PQP 167
           P+++  A+   ++SD    A++   P G   A   R+ + P+    G  GGL   P P+ 
Sbjct: 593 PASAEEAIPLPASSDSERSASSVEGPGGALYARVARREARPARAR-GEIGGLSLSPSPER 651

Query: 168 RRAAPTTP--PPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLD-TLYTSSS 224
           R+  P  P   P V     +   A+     +  P G  +  S S    T  D + +T   
Sbjct: 652 RKPPPPDPATKPKVSWIHGKHSAAAAGRAPSPPPPGSEAAPSPSKRKRTPSDKSAHTVEH 711

Query: 225 PSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKA-SAPEPPAEEEVATGTTSASDDLEAL 283
            S      +P PP +P     T ++   PP ++A +AP P             ++    L
Sbjct: 712 GSPRTRDPTPRPPGLPEEA--TALAAPSPPRARARAAPRPLGAHGRRRSPAKRAEAASML 769

Query: 284 GTLSLGTTEEKAAAEAAV 301
                G T     AE A+
Sbjct: 770 AADVRGKTRSLGRAEVAL 787


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.132    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,862,036
Number of Sequences: 37866
Number of extensions: 1560068
Number of successful extensions: 16606
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 213
Number of HSP's successfully gapped in prelim test: 799
Number of HSP's that attempted gapping in prelim test: 11614
Number of HSP's gapped (non-prelim): 4386
length of query: 715
length of database: 18,247,518
effective HSP length: 109
effective length of query: 606
effective length of database: 14,120,124
effective search space: 8556795144
effective search space used: 8556795144
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.