Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 35038528
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|35038528 PAS domain containing serine/threonine kinase [Homo
sapiens]
(1323 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|35038528 PAS domain containing serine/threonine kinase [Homo ... 2681 0.0
gi|7662170 AMPK-related protein kinase 5 [Homo sapiens] 160 6e-39
gi|24308326 BR serine/threonine kinase 1 [Homo sapiens] 159 2e-38
gi|254028240 MAP/microtubule affinity-regulating kinase 2 isofor... 156 1e-37
gi|254028237 MAP/microtubule affinity-regulating kinase 2 isofor... 156 1e-37
gi|254028234 MAP/microtubule affinity-regulating kinase 2 isofor... 156 1e-37
gi|254028232 MAP/microtubule affinity-regulating kinase 2 isofor... 156 1e-37
gi|86990441 MAP/microtubule affinity-regulating kinase 2 isoform... 156 1e-37
gi|33636756 MAP/microtubule affinity-regulating kinase 4 [Homo s... 155 2e-37
gi|193083129 MAP/microtubule affinity-regulating kinase 3 isofor... 154 5e-37
gi|193083127 MAP/microtubule affinity-regulating kinase 3 isofor... 154 5e-37
gi|193083125 MAP/microtubule affinity-regulating kinase 3 isofor... 154 5e-37
gi|46852166 MAP/microtubule affinity-regulating kinase 3 isoform... 154 5e-37
gi|153791472 MAP/microtubule affinity-regulating kinase 1 [Homo ... 152 2e-36
gi|13569922 NUAK family, SNF1-like kinase, 2 [Homo sapiens] 152 3e-36
gi|116089335 BR serine/threonine kinase 2 [Homo sapiens] 150 1e-35
gi|156105707 SNF related kinase [Homo sapiens] 149 1e-35
gi|156105705 SNF related kinase [Homo sapiens] 149 1e-35
gi|38569460 SNF1-like kinase 2 [Homo sapiens] 145 3e-34
gi|224591416 serine/threonine protein kinase pim-3 [Homo sapiens] 140 8e-33
gi|4505811 non-specific serine/threonine protein kinase [Homo sa... 140 8e-33
gi|42821112 serine/threonine protein kinase pim-2 [Homo sapiens] 140 1e-32
gi|23503303 serine/threonine-protein kinase NIM1 [Homo sapiens] 137 9e-32
gi|116256471 SNF1-like kinase [Homo sapiens] 135 2e-31
gi|94557301 protein kinase, AMP-activated, alpha 1 catalytic sub... 134 4e-31
gi|46877068 AMP-activated protein kinase alpha 2 catalytic subun... 134 4e-31
gi|38569491 serine/threonine-protein kinase QSK [Homo sapiens] 133 1e-30
gi|7657214 hormonally upregulated Neu-associated kinase [Homo sa... 128 3e-29
gi|7661974 maternal embryonic leucine zipper kinase [Homo sapiens] 128 3e-29
gi|194294513 testis-specific serine kinase 2 [Homo sapiens] 128 4e-29
>gi|35038528 PAS domain containing serine/threonine kinase [Homo
sapiens]
Length = 1323
Score = 2681 bits (6950), Expect = 0.0
Identities = 1323/1323 (100%), Positives = 1323/1323 (100%)
Query: 1 MEDGGLTAFEEDQRCLSQSLPLPVSAEGPAAQTTAEPSRSFSSAHRHLSRRNGLSRLCQS 60
MEDGGLTAFEEDQRCLSQSLPLPVSAEGPAAQTTAEPSRSFSSAHRHLSRRNGLSRLCQS
Sbjct: 1 MEDGGLTAFEEDQRCLSQSLPLPVSAEGPAAQTTAEPSRSFSSAHRHLSRRNGLSRLCQS 60
Query: 61 RTALSEDRWSSYCLSSLAAQNICTSKLHCPAAPEHTDPSEPRGSVSCCSLLRGLSSGWSS 120
RTALSEDRWSSYCLSSLAAQNICTSKLHCPAAPEHTDPSEPRGSVSCCSLLRGLSSGWSS
Sbjct: 61 RTALSEDRWSSYCLSSLAAQNICTSKLHCPAAPEHTDPSEPRGSVSCCSLLRGLSSGWSS 120
Query: 121 PLLPAPVCNPNKAIFTVDAKTTEILVANDKACGLLGYSSQDLIGQKLTQFFLRSDSDVVE 180
PLLPAPVCNPNKAIFTVDAKTTEILVANDKACGLLGYSSQDLIGQKLTQFFLRSDSDVVE
Sbjct: 121 PLLPAPVCNPNKAIFTVDAKTTEILVANDKACGLLGYSSQDLIGQKLTQFFLRSDSDVVE 180
Query: 181 ALSEEHMEADGHAAVVFGTVVDIISRSGEKIPVSVWMKRMRQERRLCCVVVLEPVERVST 240
ALSEEHMEADGHAAVVFGTVVDIISRSGEKIPVSVWMKRMRQERRLCCVVVLEPVERVST
Sbjct: 181 ALSEEHMEADGHAAVVFGTVVDIISRSGEKIPVSVWMKRMRQERRLCCVVVLEPVERVST 240
Query: 241 WVAFQSDGTVTSCDSLFAHLHGYVSGEDVAGQHITDLIPSVQLPPSGQHIPKNLKIQRSV 300
WVAFQSDGTVTSCDSLFAHLHGYVSGEDVAGQHITDLIPSVQLPPSGQHIPKNLKIQRSV
Sbjct: 241 WVAFQSDGTVTSCDSLFAHLHGYVSGEDVAGQHITDLIPSVQLPPSGQHIPKNLKIQRSV 300
Query: 301 GRARDGTTFPLSLKLKSQPSSEEATTGEAAPVSGYRASVWVFCTISGLITLLPDGTIHGI 360
GRARDGTTFPLSLKLKSQPSSEEATTGEAAPVSGYRASVWVFCTISGLITLLPDGTIHGI
Sbjct: 301 GRARDGTTFPLSLKLKSQPSSEEATTGEAAPVSGYRASVWVFCTISGLITLLPDGTIHGI 360
Query: 361 NHSFALTLFGYGKTELLGKNITFLIPGFYSYMDLAYNSSLQLPDLASCLDVGNESGCGER 420
NHSFALTLFGYGKTELLGKNITFLIPGFYSYMDLAYNSSLQLPDLASCLDVGNESGCGER
Sbjct: 361 NHSFALTLFGYGKTELLGKNITFLIPGFYSYMDLAYNSSLQLPDLASCLDVGNESGCGER 420
Query: 421 TLDPWQGQDPAEGGQDPRINVVLAGGHVVPRDEIRKLMESQDIFTGTQTELIAGGQLLSC 480
TLDPWQGQDPAEGGQDPRINVVLAGGHVVPRDEIRKLMESQDIFTGTQTELIAGGQLLSC
Sbjct: 421 TLDPWQGQDPAEGGQDPRINVVLAGGHVVPRDEIRKLMESQDIFTGTQTELIAGGQLLSC 480
Query: 481 LSPQPAPGVDNVPEGSLPVHGEQALPKDQQITALGREEPVAIESPGQDLLGESRSEPVDV 540
LSPQPAPGVDNVPEGSLPVHGEQALPKDQQITALGREEPVAIESPGQDLLGESRSEPVDV
Sbjct: 481 LSPQPAPGVDNVPEGSLPVHGEQALPKDQQITALGREEPVAIESPGQDLLGESRSEPVDV 540
Query: 541 KPFASCEDSEAPVPAEDGGSDAGMCGLCQKAQLERMGVSGPSGSDLWAGAAVAKPQAKGQ 600
KPFASCEDSEAPVPAEDGGSDAGMCGLCQKAQLERMGVSGPSGSDLWAGAAVAKPQAKGQ
Sbjct: 541 KPFASCEDSEAPVPAEDGGSDAGMCGLCQKAQLERMGVSGPSGSDLWAGAAVAKPQAKGQ 600
Query: 601 LAGGSLLMHCPCYGSEWGLWWRSQDLAPSPSGMAGLSFGTPTLDEPWLGVENDREELQTC 660
LAGGSLLMHCPCYGSEWGLWWRSQDLAPSPSGMAGLSFGTPTLDEPWLGVENDREELQTC
Sbjct: 601 LAGGSLLMHCPCYGSEWGLWWRSQDLAPSPSGMAGLSFGTPTLDEPWLGVENDREELQTC 660
Query: 661 LIKEQLSQLSLAGALDVPHAELVPTECQAVTAPVSSCDLGGRDLCGGCTGSSSACYALAT 720
LIKEQLSQLSLAGALDVPHAELVPTECQAVTAPVSSCDLGGRDLCGGCTGSSSACYALAT
Sbjct: 661 LIKEQLSQLSLAGALDVPHAELVPTECQAVTAPVSSCDLGGRDLCGGCTGSSSACYALAT 720
Query: 721 DLPGGLEAVEAQEVDVNSFSWNLKELFFSDQTDQTSSNCSCATSELRETPSSLAVGSDPD 780
DLPGGLEAVEAQEVDVNSFSWNLKELFFSDQTDQTSSNCSCATSELRETPSSLAVGSDPD
Sbjct: 721 DLPGGLEAVEAQEVDVNSFSWNLKELFFSDQTDQTSSNCSCATSELRETPSSLAVGSDPD 780
Query: 781 VGSLQEQGSCVLDDRELLLLTGTCVDLGQGRRFRESCVGHDPTEPLEVCLVSSEHYAASD 840
VGSLQEQGSCVLDDRELLLLTGTCVDLGQGRRFRESCVGHDPTEPLEVCLVSSEHYAASD
Sbjct: 781 VGSLQEQGSCVLDDRELLLLTGTCVDLGQGRRFRESCVGHDPTEPLEVCLVSSEHYAASD 840
Query: 841 RESPGHVPSTLDAGPEDTCPSAEEPRLNVQVTSTPVIVMRGAAGLQREIQEGAYSGSCYH 900
RESPGHVPSTLDAGPEDTCPSAEEPRLNVQVTSTPVIVMRGAAGLQREIQEGAYSGSCYH
Sbjct: 841 RESPGHVPSTLDAGPEDTCPSAEEPRLNVQVTSTPVIVMRGAAGLQREIQEGAYSGSCYH 900
Query: 901 RDGLRLSIQFEVRRVELQGPTPLFCCWLVKDLLHSQRDSAARTRLFLASLPGSTHSTAAE 960
RDGLRLSIQFEVRRVELQGPTPLFCCWLVKDLLHSQRDSAARTRLFLASLPGSTHSTAAE
Sbjct: 901 RDGLRLSIQFEVRRVELQGPTPLFCCWLVKDLLHSQRDSAARTRLFLASLPGSTHSTAAE 960
Query: 961 LTGPSLVEVLRARPWFEEPPKAVELEGLAACEGEYSQKYSTMSPLGSGAFGFVWTAVDKE 1020
LTGPSLVEVLRARPWFEEPPKAVELEGLAACEGEYSQKYSTMSPLGSGAFGFVWTAVDKE
Sbjct: 961 LTGPSLVEVLRARPWFEEPPKAVELEGLAACEGEYSQKYSTMSPLGSGAFGFVWTAVDKE 1020
Query: 1021 KNKEVVVKFIKKEKVLEDCWIEDPKLGKVTLEIAILSRVEHANIIKVLDIFENQGFFQLV 1080
KNKEVVVKFIKKEKVLEDCWIEDPKLGKVTLEIAILSRVEHANIIKVLDIFENQGFFQLV
Sbjct: 1021 KNKEVVVKFIKKEKVLEDCWIEDPKLGKVTLEIAILSRVEHANIIKVLDIFENQGFFQLV 1080
Query: 1081 MEKHGSGLDLFAFIDRHPRLDEPLASYIFRQLVSAVGYLRLKDIIHRDIKDENIVIAEDF 1140
MEKHGSGLDLFAFIDRHPRLDEPLASYIFRQLVSAVGYLRLKDIIHRDIKDENIVIAEDF
Sbjct: 1081 MEKHGSGLDLFAFIDRHPRLDEPLASYIFRQLVSAVGYLRLKDIIHRDIKDENIVIAEDF 1140
Query: 1141 TIKLIDFGSAAYLERGKLFYTFCGTIEYCAPEVLMGNPYRGPELEMWSLGVTLYTLVFEE 1200
TIKLIDFGSAAYLERGKLFYTFCGTIEYCAPEVLMGNPYRGPELEMWSLGVTLYTLVFEE
Sbjct: 1141 TIKLIDFGSAAYLERGKLFYTFCGTIEYCAPEVLMGNPYRGPELEMWSLGVTLYTLVFEE 1200
Query: 1201 NPFCELEETVEAAIHPPYLVSKELMSLVSGLLQPVPERRTTLEKLVTDPWVTQPVNLADY 1260
NPFCELEETVEAAIHPPYLVSKELMSLVSGLLQPVPERRTTLEKLVTDPWVTQPVNLADY
Sbjct: 1201 NPFCELEETVEAAIHPPYLVSKELMSLVSGLLQPVPERRTTLEKLVTDPWVTQPVNLADY 1260
Query: 1261 TWEEVFRVNKPESGVLSAASLEMGNRSLSDVAQAQELCGGPVPGEAPNGQGCLHPGDPRL 1320
TWEEVFRVNKPESGVLSAASLEMGNRSLSDVAQAQELCGGPVPGEAPNGQGCLHPGDPRL
Sbjct: 1261 TWEEVFRVNKPESGVLSAASLEMGNRSLSDVAQAQELCGGPVPGEAPNGQGCLHPGDPRL 1320
Query: 1321 LTS 1323
LTS
Sbjct: 1321 LTS 1323
>gi|7662170 AMPK-related protein kinase 5 [Homo sapiens]
Length = 661
Score = 160 bits (406), Expect = 6e-39
Identities = 86/259 (33%), Positives = 141/259 (54%), Gaps = 11/259 (4%)
Query: 998 KYSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVTLEIAILS 1057
+Y LG G +G V A ++ + V +K I+K+K+ ++ + + EI I+S
Sbjct: 54 RYELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDE-----QDMVHIRREIEIMS 108
Query: 1058 RVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQLVSAVG 1117
+ H +II + ++FEN+ ++ME G +L+ +I RL E + FRQ+VSAV
Sbjct: 109 SLNHPHIISIYEVFENKDKIVIIMEYASKG-ELYDYISERRRLSERETRHFFRQIVSAVH 167
Query: 1118 YLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGKLFYTFCGTIEYCAPEVLMGN 1177
Y ++HRD+K ENI++ ++ IK+ DFG + ++ K TFCG+ Y +PE++ G
Sbjct: 168 YCHKNGVVHRDLKLENILLDDNCNIKIADFGLSNLYQKDKFLQTFCGSPLYASPEIVNGR 227
Query: 1178 PYRGPELEMWSLGVTLYTLVFEENPF-----CELEETVEAAIHPPYLVSKELMSLVSGLL 1232
PYRGPE++ W+LGV LYTLV+ PF L + + + + L+ +L
Sbjct: 228 PYRGPEVDSWALGVLLYTLVYGTMPFDGFDHKNLIRQISSGEYREPTQPSDARGLIRWML 287
Query: 1233 QPVPERRTTLEKLVTDPWV 1251
P+RR T+E + WV
Sbjct: 288 MVNPDRRATIEDIANHWWV 306
>gi|24308326 BR serine/threonine kinase 1 [Homo sapiens]
Length = 778
Score = 159 bits (402), Expect = 2e-38
Identities = 91/263 (34%), Positives = 140/263 (53%), Gaps = 13/263 (4%)
Query: 994 EYSQKYSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVTLEI 1053
+Y Y LG G G V V ++V +K + +EK+ E L KV EI
Sbjct: 29 QYVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESV------LMKVEREI 82
Query: 1054 AILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQLV 1113
AIL +EH +++K+ D++EN+ + LV+E H SG +LF ++ + RL A FRQ+V
Sbjct: 83 AILKLIEHPHVLKLHDVYENKKYLYLVLE-HVSGGELFDYLVKKGRLTPKEARKFFRQIV 141
Query: 1114 SAVGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGKLFYTFCGTIEYCAPEV 1173
SA+ + I HRD+K EN+++ E I++ DFG A+ L T CG+ Y PEV
Sbjct: 142 SALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEV 201
Query: 1174 LMGNPYRGPELEMWSLGVTLYTLVFEENPFCE------LEETVEAAIHPPYLVSKELMSL 1227
+ G Y G +MWS GV L+ L+ PF + LE+ H P+ + + SL
Sbjct: 202 IKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSL 261
Query: 1228 VSGLLQPVPERRTTLEKLVTDPW 1250
+ G+++ PE+R +LE++ PW
Sbjct: 262 LRGMIEVEPEKRLSLEQIQKHPW 284
>gi|254028240 MAP/microtubule affinity-regulating kinase 2 isoform f
[Homo sapiens]
Length = 709
Score = 156 bits (394), Expect = 1e-37
Identities = 98/269 (36%), Positives = 142/269 (52%), Gaps = 13/269 (4%)
Query: 989 AACEGEYSQKYSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGK 1048
+A E + Y + +G G F V A KEV VK I K + + L K
Sbjct: 43 SADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQ------LNSSSLQK 96
Query: 1049 VTLEIAILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYI 1108
+ E+ I+ + H NI+K+ ++ E + LVME + SG ++F ++ H R+ E A
Sbjct: 97 LFREVRIMKVLNHPNIVKLFEVIETEKTLYLVME-YASGGEVFDYLVAHGRMKEKEARAK 155
Query: 1109 FRQLVSAVGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGKLFYTFCGTIEY 1168
FRQ+VSAV Y K I+HRD+K EN+++ D IK+ DFG + G TFCG+ Y
Sbjct: 156 FRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPY 215
Query: 1169 CAPEVLMGNPYRGPELEMWSLGVTLYTLVFEENPF-----CELEETV-EAAIHPPYLVSK 1222
APE+ G Y GPE+++WSLGV LYTLV PF EL E V P+ +S
Sbjct: 216 AAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMST 275
Query: 1223 ELMSLVSGLLQPVPERRTTLEKLVTDPWV 1251
+ +L+ L P +R TLE+++ D W+
Sbjct: 276 DCENLLKKFLILNPSKRGTLEQIMKDRWM 304
>gi|254028237 MAP/microtubule affinity-regulating kinase 2 isoform e
[Homo sapiens]
Length = 719
Score = 156 bits (394), Expect = 1e-37
Identities = 98/269 (36%), Positives = 142/269 (52%), Gaps = 13/269 (4%)
Query: 989 AACEGEYSQKYSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGK 1048
+A E + Y + +G G F V A KEV VK I K + + L K
Sbjct: 43 SADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQ------LNSSSLQK 96
Query: 1049 VTLEIAILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYI 1108
+ E+ I+ + H NI+K+ ++ E + LVME + SG ++F ++ H R+ E A
Sbjct: 97 LFREVRIMKVLNHPNIVKLFEVIETEKTLYLVME-YASGGEVFDYLVAHGRMKEKEARAK 155
Query: 1109 FRQLVSAVGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGKLFYTFCGTIEY 1168
FRQ+VSAV Y K I+HRD+K EN+++ D IK+ DFG + G TFCG+ Y
Sbjct: 156 FRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPY 215
Query: 1169 CAPEVLMGNPYRGPELEMWSLGVTLYTLVFEENPF-----CELEETV-EAAIHPPYLVSK 1222
APE+ G Y GPE+++WSLGV LYTLV PF EL E V P+ +S
Sbjct: 216 AAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMST 275
Query: 1223 ELMSLVSGLLQPVPERRTTLEKLVTDPWV 1251
+ +L+ L P +R TLE+++ D W+
Sbjct: 276 DCENLLKKFLILNPSKRGTLEQIMKDRWM 304
>gi|254028234 MAP/microtubule affinity-regulating kinase 2 isoform d
[Homo sapiens]
Length = 788
Score = 156 bits (394), Expect = 1e-37
Identities = 98/269 (36%), Positives = 142/269 (52%), Gaps = 13/269 (4%)
Query: 989 AACEGEYSQKYSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGK 1048
+A E + Y + +G G F V A KEV VK I K + + L K
Sbjct: 43 SADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQ------LNSSSLQK 96
Query: 1049 VTLEIAILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYI 1108
+ E+ I+ + H NI+K+ ++ E + LVME + SG ++F ++ H R+ E A
Sbjct: 97 LFREVRIMKVLNHPNIVKLFEVIETEKTLYLVME-YASGGEVFDYLVAHGRMKEKEARAK 155
Query: 1109 FRQLVSAVGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGKLFYTFCGTIEY 1168
FRQ+VSAV Y K I+HRD+K EN+++ D IK+ DFG + G TFCG+ Y
Sbjct: 156 FRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPY 215
Query: 1169 CAPEVLMGNPYRGPELEMWSLGVTLYTLVFEENPF-----CELEETV-EAAIHPPYLVSK 1222
APE+ G Y GPE+++WSLGV LYTLV PF EL E V P+ +S
Sbjct: 216 AAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMST 275
Query: 1223 ELMSLVSGLLQPVPERRTTLEKLVTDPWV 1251
+ +L+ L P +R TLE+++ D W+
Sbjct: 276 DCENLLKKFLILNPSKRGTLEQIMKDRWM 304
>gi|254028232 MAP/microtubule affinity-regulating kinase 2 isoform c
[Homo sapiens]
Length = 724
Score = 156 bits (394), Expect = 1e-37
Identities = 98/269 (36%), Positives = 142/269 (52%), Gaps = 13/269 (4%)
Query: 989 AACEGEYSQKYSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGK 1048
+A E + Y + +G G F V A KEV VK I K + + L K
Sbjct: 43 SADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQ------LNSSSLQK 96
Query: 1049 VTLEIAILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYI 1108
+ E+ I+ + H NI+K+ ++ E + LVME + SG ++F ++ H R+ E A
Sbjct: 97 LFREVRIMKVLNHPNIVKLFEVIETEKTLYLVME-YASGGEVFDYLVAHGRMKEKEARAK 155
Query: 1109 FRQLVSAVGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGKLFYTFCGTIEY 1168
FRQ+VSAV Y K I+HRD+K EN+++ D IK+ DFG + G TFCG+ Y
Sbjct: 156 FRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPY 215
Query: 1169 CAPEVLMGNPYRGPELEMWSLGVTLYTLVFEENPF-----CELEETV-EAAIHPPYLVSK 1222
APE+ G Y GPE+++WSLGV LYTLV PF EL E V P+ +S
Sbjct: 216 AAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMST 275
Query: 1223 ELMSLVSGLLQPVPERRTTLEKLVTDPWV 1251
+ +L+ L P +R TLE+++ D W+
Sbjct: 276 DCENLLKKFLILNPSKRGTLEQIMKDRWM 304
>gi|86990441 MAP/microtubule affinity-regulating kinase 2 isoform a
[Homo sapiens]
Length = 745
Score = 156 bits (394), Expect = 1e-37
Identities = 98/269 (36%), Positives = 142/269 (52%), Gaps = 13/269 (4%)
Query: 989 AACEGEYSQKYSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGK 1048
+A E + Y + +G G F V A KEV VK I K + + L K
Sbjct: 10 SADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQ------LNSSSLQK 63
Query: 1049 VTLEIAILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYI 1108
+ E+ I+ + H NI+K+ ++ E + LVME + SG ++F ++ H R+ E A
Sbjct: 64 LFREVRIMKVLNHPNIVKLFEVIETEKTLYLVME-YASGGEVFDYLVAHGRMKEKEARAK 122
Query: 1109 FRQLVSAVGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGKLFYTFCGTIEY 1168
FRQ+VSAV Y K I+HRD+K EN+++ D IK+ DFG + G TFCG+ Y
Sbjct: 123 FRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPY 182
Query: 1169 CAPEVLMGNPYRGPELEMWSLGVTLYTLVFEENPF-----CELEETV-EAAIHPPYLVSK 1222
APE+ G Y GPE+++WSLGV LYTLV PF EL E V P+ +S
Sbjct: 183 AAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMST 242
Query: 1223 ELMSLVSGLLQPVPERRTTLEKLVTDPWV 1251
+ +L+ L P +R TLE+++ D W+
Sbjct: 243 DCENLLKKFLILNPSKRGTLEQIMKDRWM 271
>gi|33636756 MAP/microtubule affinity-regulating kinase 4 [Homo
sapiens]
Length = 688
Score = 155 bits (393), Expect = 2e-37
Identities = 100/293 (34%), Positives = 150/293 (51%), Gaps = 20/293 (6%)
Query: 988 LAACEGEYSQ--KYSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPK 1045
+A+C E Y + +G G F V A +EV +K I K + +
Sbjct: 46 IASCPEEQPHVGNYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQ------LNPSS 99
Query: 1046 LGKVTLEIAILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLA 1105
L K+ E+ I+ + H NI+K+ ++ E + LVME +G ++F ++ H R+ E A
Sbjct: 100 LQKLFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAG-EVFDYLVSHGRMKEKEA 158
Query: 1106 SYIFRQLVSAVGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGKLFYTFCGT 1165
FRQ+VSAV Y K+I+HRD+K EN+++ + IK+ DFG + G TFCG+
Sbjct: 159 RAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGS 218
Query: 1166 IEYCAPEVLMGNPYRGPELEMWSLGVTLYTLVFEENPF-----CELEETV-EAAIHPPYL 1219
Y APE+ G Y GPE+++WSLGV LYTLV PF EL E V P+
Sbjct: 219 PPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFY 278
Query: 1220 VSKELMSLVSGLLQPVPERRTTLEKLVTDPWVTQPVNLADYTWEEVFRVNKPE 1272
+S + S++ L P +R TLE+++ D W+ Y EE+ +PE
Sbjct: 279 MSTDCESILRRFLVLNPAKRCTLEQIMKDKWIN-----IGYEGEELKPYTEPE 326
>gi|193083129 MAP/microtubule affinity-regulating kinase 3 isoform d
[Homo sapiens]
Length = 713
Score = 154 bits (389), Expect = 5e-37
Identities = 96/272 (35%), Positives = 143/272 (52%), Gaps = 15/272 (5%)
Query: 988 LAACEGEYSQ--KYSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPK 1045
+A+C E Y + +G G F V A +EV +K I K + +
Sbjct: 43 IASCADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQ------LNPTS 96
Query: 1046 LGKVTLEIAILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLA 1105
L K+ E+ I+ + H NI+K+ ++ E + L+ME + SG ++F ++ H R+ E A
Sbjct: 97 LQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLIME-YASGGEVFDYLVAHGRMKEKEA 155
Query: 1106 SYIFRQLVSAVGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGKLFYTFCGT 1165
FRQ+VSAV Y K I+HRD+K EN+++ D IK+ DFG + G TFCG+
Sbjct: 156 RSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGS 215
Query: 1166 IEYCAPEVLMGNPYRGPELEMWSLGVTLYTLVFEENPF-----CELEETV-EAAIHPPYL 1219
Y APE+ G Y GPE+++WSLGV LYTLV PF EL E V P+
Sbjct: 216 PPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFY 275
Query: 1220 VSKELMSLVSGLLQPVPERRTTLEKLVTDPWV 1251
+S + +L+ L P +R TLE+++ D W+
Sbjct: 276 MSTDCENLLKRFLVLNPIKRGTLEQIMKDRWI 307
>gi|193083127 MAP/microtubule affinity-regulating kinase 3 isoform b
[Homo sapiens]
Length = 744
Score = 154 bits (389), Expect = 5e-37
Identities = 96/272 (35%), Positives = 143/272 (52%), Gaps = 15/272 (5%)
Query: 988 LAACEGEYSQ--KYSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPK 1045
+A+C E Y + +G G F V A +EV +K I K + +
Sbjct: 43 IASCADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQ------LNPTS 96
Query: 1046 LGKVTLEIAILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLA 1105
L K+ E+ I+ + H NI+K+ ++ E + L+ME + SG ++F ++ H R+ E A
Sbjct: 97 LQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLIME-YASGGEVFDYLVAHGRMKEKEA 155
Query: 1106 SYIFRQLVSAVGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGKLFYTFCGT 1165
FRQ+VSAV Y K I+HRD+K EN+++ D IK+ DFG + G TFCG+
Sbjct: 156 RSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGS 215
Query: 1166 IEYCAPEVLMGNPYRGPELEMWSLGVTLYTLVFEENPF-----CELEETV-EAAIHPPYL 1219
Y APE+ G Y GPE+++WSLGV LYTLV PF EL E V P+
Sbjct: 216 PPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFY 275
Query: 1220 VSKELMSLVSGLLQPVPERRTTLEKLVTDPWV 1251
+S + +L+ L P +R TLE+++ D W+
Sbjct: 276 MSTDCENLLKRFLVLNPIKRGTLEQIMKDRWI 307
>gi|193083125 MAP/microtubule affinity-regulating kinase 3 isoform a
[Homo sapiens]
Length = 753
Score = 154 bits (389), Expect = 5e-37
Identities = 96/272 (35%), Positives = 143/272 (52%), Gaps = 15/272 (5%)
Query: 988 LAACEGEYSQ--KYSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPK 1045
+A+C E Y + +G G F V A +EV +K I K + +
Sbjct: 43 IASCADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQ------LNPTS 96
Query: 1046 LGKVTLEIAILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLA 1105
L K+ E+ I+ + H NI+K+ ++ E + L+ME + SG ++F ++ H R+ E A
Sbjct: 97 LQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLIME-YASGGEVFDYLVAHGRMKEKEA 155
Query: 1106 SYIFRQLVSAVGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGKLFYTFCGT 1165
FRQ+VSAV Y K I+HRD+K EN+++ D IK+ DFG + G TFCG+
Sbjct: 156 RSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGS 215
Query: 1166 IEYCAPEVLMGNPYRGPELEMWSLGVTLYTLVFEENPF-----CELEETV-EAAIHPPYL 1219
Y APE+ G Y GPE+++WSLGV LYTLV PF EL E V P+
Sbjct: 216 PPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFY 275
Query: 1220 VSKELMSLVSGLLQPVPERRTTLEKLVTDPWV 1251
+S + +L+ L P +R TLE+++ D W+
Sbjct: 276 MSTDCENLLKRFLVLNPIKRGTLEQIMKDRWI 307
>gi|46852166 MAP/microtubule affinity-regulating kinase 3 isoform c
[Homo sapiens]
Length = 729
Score = 154 bits (389), Expect = 5e-37
Identities = 96/272 (35%), Positives = 143/272 (52%), Gaps = 15/272 (5%)
Query: 988 LAACEGEYSQ--KYSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPK 1045
+A+C E Y + +G G F V A +EV +K I K + +
Sbjct: 43 IASCADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQ------LNPTS 96
Query: 1046 LGKVTLEIAILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLA 1105
L K+ E+ I+ + H NI+K+ ++ E + L+ME + SG ++F ++ H R+ E A
Sbjct: 97 LQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLIME-YASGGEVFDYLVAHGRMKEKEA 155
Query: 1106 SYIFRQLVSAVGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGKLFYTFCGT 1165
FRQ+VSAV Y K I+HRD+K EN+++ D IK+ DFG + G TFCG+
Sbjct: 156 RSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGS 215
Query: 1166 IEYCAPEVLMGNPYRGPELEMWSLGVTLYTLVFEENPF-----CELEETV-EAAIHPPYL 1219
Y APE+ G Y GPE+++WSLGV LYTLV PF EL E V P+
Sbjct: 216 PPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFY 275
Query: 1220 VSKELMSLVSGLLQPVPERRTTLEKLVTDPWV 1251
+S + +L+ L P +R TLE+++ D W+
Sbjct: 276 MSTDCENLLKRFLVLNPIKRGTLEQIMKDRWI 307
>gi|153791472 MAP/microtubule affinity-regulating kinase 1 [Homo
sapiens]
Length = 795
Score = 152 bits (385), Expect = 2e-36
Identities = 97/269 (36%), Positives = 141/269 (52%), Gaps = 13/269 (4%)
Query: 989 AACEGEYSQKYSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGK 1048
A E + Y +G G F V A +EV VK I K + + L K
Sbjct: 50 ATDEQPHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQ------LNPTSLQK 103
Query: 1049 VTLEIAILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYI 1108
+ E+ I+ + H NI+K+ ++ E + LVME + SG ++F ++ H R+ E A
Sbjct: 104 LFREVRIMKILNHPNIVKLFEVIETEKTLYLVME-YASGGEVFDYLVAHGRMKEKEARAK 162
Query: 1109 FRQLVSAVGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGKLFYTFCGTIEY 1168
FRQ+VSAV Y K I+HRD+K EN+++ D IK+ DFG + G TFCG+ Y
Sbjct: 163 FRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPY 222
Query: 1169 CAPEVLMGNPYRGPELEMWSLGVTLYTLVFEENPF-----CELEETV-EAAIHPPYLVSK 1222
APE+ G Y GPE+++WSLGV LYTLV PF EL E V P+ +S
Sbjct: 223 AAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMST 282
Query: 1223 ELMSLVSGLLQPVPERRTTLEKLVTDPWV 1251
+ +L+ LL P +R +LE+++ D W+
Sbjct: 283 DCENLLKKLLVLNPIKRGSLEQIMKDRWM 311
>gi|13569922 NUAK family, SNF1-like kinase, 2 [Homo sapiens]
Length = 628
Score = 152 bits (383), Expect = 3e-36
Identities = 93/260 (35%), Positives = 139/260 (53%), Gaps = 14/260 (5%)
Query: 998 KYSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVTLEIAILS 1057
+Y + LG G +G V A + + V +K I+K+K+ ++ L + EI I+S
Sbjct: 52 RYEFLETLGKGTYGKVKKARESS-GRLVAIKSIRKDKIKDE-----QDLMHIRREIEIMS 105
Query: 1058 RVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQLVSAVG 1117
+ H +II + ++FEN +VME G DL+ +I +L E A + FRQ+VSAV
Sbjct: 106 SLNHPHIIAIHEVFENSSKIVIVMEYASRG-DLYDYISERQQLSEREARHFFRQIVSAVH 164
Query: 1118 YLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGKLFYTFCGTIEYCAPEVLMGN 1177
Y ++HRD+K ENI++ + IK+ DFG + +GK TFCG+ Y +PE++ G
Sbjct: 165 YCHQNRVVHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGK 224
Query: 1178 PYRGPELEMWSLGVTLYTLVFEENPF------CELEETVEAAIHPPYLVSKELMSLVSGL 1231
PY GPE++ WSLGV LY LV PF +++ A P S + L+ L
Sbjct: 225 PYTGPEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPKPS-DACGLIRWL 283
Query: 1232 LQPVPERRTTLEKLVTDPWV 1251
L P RR TLE + + WV
Sbjct: 284 LMVNPTRRATLEDVASHWWV 303
>gi|116089335 BR serine/threonine kinase 2 [Homo sapiens]
Length = 668
Score = 150 bits (378), Expect = 1e-35
Identities = 89/267 (33%), Positives = 138/267 (51%), Gaps = 13/267 (4%)
Query: 990 ACEGEYSQKYSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKV 1049
A +Y Y LG G G V V ++V +K + +EK+ E L KV
Sbjct: 10 AQHAQYVGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESV------LMKV 63
Query: 1050 TLEIAILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIF 1109
EIAIL +EH +++K+ D++EN+ + LV+E H SG +LF ++ + RL A F
Sbjct: 64 EREIAILKLIEHPHVLKLHDVYENKKYLYLVLE-HVSGGELFDYLVKKGRLTPKEARKFF 122
Query: 1110 RQLVSAVGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGKLFYTFCGTIEYC 1169
RQ++SA+ + I HRD+K EN+++ E I++ DFG A+ L T CG+ Y
Sbjct: 123 RQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYA 182
Query: 1170 APEVLMGNPYRGPELEMWSLGVTLYTLVFEENPFCE------LEETVEAAIHPPYLVSKE 1223
PEV+ G Y G + ++WS GV L+ L+ PF + LE+ H P+ + +
Sbjct: 183 CPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPD 242
Query: 1224 LMSLVSGLLQPVPERRTTLEKLVTDPW 1250
SL+ G+++ RR TLE + W
Sbjct: 243 CQSLLRGMIEVDAARRLTLEHIQKHIW 269
>gi|156105707 SNF related kinase [Homo sapiens]
Length = 765
Score = 149 bits (377), Expect = 1e-35
Identities = 90/268 (33%), Positives = 144/268 (53%), Gaps = 15/268 (5%)
Query: 992 EGEYSQKYSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVTL 1051
+G+ + Y LG G F V A ++V VK I K K ++ G +
Sbjct: 9 DGKIAGLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTK------LDTLATGHLFQ 62
Query: 1052 EIAILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPR-LDEPLASYIFR 1110
E+ + V+H NI+++ ++ + Q L++E G G D+F +I +H L+E LA F
Sbjct: 63 EVRCMKLVQHPNIVRLYEVIDTQTKLYLILEL-GDGGDMFDYIMKHEEGLNEDLAKKYFA 121
Query: 1111 QLVSAVGYLRLKDIIHRDIKDENIVIAE-DFTIKLIDFGSAAYLERGKLFYTFCGTIEYC 1169
Q+V A+ Y ++HRD+K EN+V E +KL DFG + + GK T CG++ Y
Sbjct: 122 QIVHAISYCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYS 181
Query: 1170 APEVLMGNPYRGPELEMWSLGVTLYTLVFEENPFCELEET------VEAAIHPPYLVSKE 1223
APE+L+G+ Y P +++WSLGV L+ LV + PF E ++ ++ P VSKE
Sbjct: 182 APEILLGDEYDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSHVSKE 241
Query: 1224 LMSLVSGLLQPVPERRTTLEKLVTDPWV 1251
L++ +LQ P+RR +LE++ PW+
Sbjct: 242 CKDLITRMLQRDPKRRASLEEIENHPWL 269
>gi|156105705 SNF related kinase [Homo sapiens]
Length = 765
Score = 149 bits (377), Expect = 1e-35
Identities = 90/268 (33%), Positives = 144/268 (53%), Gaps = 15/268 (5%)
Query: 992 EGEYSQKYSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVTL 1051
+G+ + Y LG G F V A ++V VK I K K ++ G +
Sbjct: 9 DGKIAGLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTK------LDTLATGHLFQ 62
Query: 1052 EIAILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPR-LDEPLASYIFR 1110
E+ + V+H NI+++ ++ + Q L++E G G D+F +I +H L+E LA F
Sbjct: 63 EVRCMKLVQHPNIVRLYEVIDTQTKLYLILEL-GDGGDMFDYIMKHEEGLNEDLAKKYFA 121
Query: 1111 QLVSAVGYLRLKDIIHRDIKDENIVIAE-DFTIKLIDFGSAAYLERGKLFYTFCGTIEYC 1169
Q+V A+ Y ++HRD+K EN+V E +KL DFG + + GK T CG++ Y
Sbjct: 122 QIVHAISYCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYS 181
Query: 1170 APEVLMGNPYRGPELEMWSLGVTLYTLVFEENPFCELEET------VEAAIHPPYLVSKE 1223
APE+L+G+ Y P +++WSLGV L+ LV + PF E ++ ++ P VSKE
Sbjct: 182 APEILLGDEYDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSHVSKE 241
Query: 1224 LMSLVSGLLQPVPERRTTLEKLVTDPWV 1251
L++ +LQ P+RR +LE++ PW+
Sbjct: 242 CKDLITRMLQRDPKRRASLEEIENHPWL 269
>gi|38569460 SNF1-like kinase 2 [Homo sapiens]
Length = 926
Score = 145 bits (366), Expect = 3e-34
Identities = 83/259 (32%), Positives = 134/259 (51%), Gaps = 13/259 (5%)
Query: 999 YSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVTLEIAILSR 1058
Y LG G F V + EV +K I K + ++ L K+ E+ I+
Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQ------LDAVNLEKIYREVQIMKM 73
Query: 1059 VEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQLVSAVGY 1118
++H +IIK+ + E + LV E +G ++F ++ H RL+E A F Q++SAV Y
Sbjct: 74 LDHPHIIKLYQVMETKSMLYLVTEYAKNG-EIFDYLANHGRLNESEARRKFWQILSAVDY 132
Query: 1119 LRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGKLFYTFCGTIEYCAPEVLMGNP 1178
+ I+HRD+K EN+++ + IK+ DFG + + G+L T+CG+ Y APEV G
Sbjct: 133 CHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGELLATWCGSPPYAAPEVFEGQQ 192
Query: 1179 YRGPELEMWSLGVTLYTLVFEENPF------CELEETVEAAIHPPYLVSKELMSLVSGLL 1232
Y GP+L++WS+GV LY LV PF + +E PY +S++ L+ +L
Sbjct: 193 YEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRML 252
Query: 1233 QPVPERRTTLEKLVTDPWV 1251
P +R T+ ++ W+
Sbjct: 253 VLDPSKRLTIAQIKEHKWM 271
>gi|224591416 serine/threonine protein kinase pim-3 [Homo sapiens]
Length = 326
Score = 140 bits (353), Expect = 8e-33
Identities = 106/306 (34%), Positives = 151/306 (49%), Gaps = 23/306 (7%)
Query: 953 STHSTAAELTGPSLVEVLRARPWFEEPPKAVELEGLAACEGEYSQKYSTMSPLGSGAFGF 1012
S + A L GP V+ L P K L+ A + + + Y + LGSG FG
Sbjct: 4 SKFGSLAHLCGPGGVDHL--------PVKI--LQPAKADKESFEKAYQVGAVLGSGGFGT 53
Query: 1013 VWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVT--LEIAILSRVEHAN----IIK 1066
V+ V VK + KE+V E W LG T LE+ +L +V A +I+
Sbjct: 54 VYAGSRIADGLPVAVKHVVKERVTE--W---GSLGGATVPLEVVLLRKVGAAGGARGVIR 108
Query: 1067 VLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQLVSAVGYLRLKDIIH 1126
+LD FE F LV+E+ DLF FI LDEPLA F Q+++AV + ++H
Sbjct: 109 LLDWFERPDGFLLVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHSCGVVH 168
Query: 1127 RDIKDENIVI-AEDFTIKLIDFGSAAYLERGKLFYTFCGTIEYCAPEVLMGNPYRGPELE 1185
RDIKDEN+++ +KLIDFGS A L + ++ F GT Y PE + + Y G
Sbjct: 169 RDIKDENLLVDLRSGELKLIDFGSGALL-KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAT 227
Query: 1186 MWSLGVTLYTLVFEENPFCELEETVEAAIHPPYLVSKELMSLVSGLLQPVPERRTTLEKL 1245
+WSLGV LY +V + PF + EE + + VS E L+ L P R +L+++
Sbjct: 228 VWSLGVLLYDMVCGDIPFEQDEEILRGRLLFRRRVSPECQQLIRWCLSLRPSERPSLDQI 287
Query: 1246 VTDPWV 1251
PW+
Sbjct: 288 AAHPWM 293
>gi|4505811 non-specific serine/threonine protein kinase [Homo
sapiens]
Length = 313
Score = 140 bits (353), Expect = 8e-33
Identities = 94/269 (34%), Positives = 139/269 (51%), Gaps = 7/269 (2%)
Query: 998 KYSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVTLEIAILS 1057
+Y LGSG FG V++ + N V +K ++K+++ + W E P +V +E+ +L
Sbjct: 37 QYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISD--WGELPNGTRVPMEVVLLK 94
Query: 1058 RVEH--ANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQLVSA 1115
+V + +I++LD FE F L++E+ DLF FI L E LA F Q++ A
Sbjct: 95 KVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEA 154
Query: 1116 VGYLRLKDIIHRDIKDENIVI-AEDFTIKLIDFGSAAYLERGKLFYTFCGTIEYCAPEVL 1174
V + ++HRDIKDENI+I +KLIDFGS A L + ++ F GT Y PE +
Sbjct: 155 VRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALL-KDTVYTDFDGTRVYSPPEWI 213
Query: 1175 MGNPYRGPELEMWSLGVTLYTLVFEENPFCELEETVEAAIHPPYLVSKELMSLVSGLLQP 1234
+ Y G +WSLG+ LY +V + PF EE + + VS E L+ L
Sbjct: 214 RYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLAL 273
Query: 1235 VPERRTTLEKLVTDPWVTQPVNLADYTWE 1263
P R T E++ PW+ Q V L T E
Sbjct: 274 RPSDRPTFEEIQNHPWM-QDVLLPQETAE 301
>gi|42821112 serine/threonine protein kinase pim-2 [Homo sapiens]
Length = 311
Score = 140 bits (352), Expect = 1e-32
Identities = 95/267 (35%), Positives = 139/267 (52%), Gaps = 12/267 (4%)
Query: 995 YSQKYSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVT--LE 1052
+ +Y LG G FG V+ +V +K I + +VL W P VT LE
Sbjct: 28 FEAEYRLGPLLGKGGFGTVFAGHRLTDRLQVAIKVIPRNRVLG--W--SPLSDSVTCPLE 83
Query: 1053 IAILSRVE----HANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYI 1108
+A+L +V H +I++LD FE Q F LV+E+ DLF +I L E +
Sbjct: 84 VALLWKVGAGGGHPGVIRLLDWFETQEGFMLVLERPLPAQDLFDYITEKGPLGEGPSRCF 143
Query: 1109 FRQLVSAVGYLRLKDIIHRDIKDENIVI-AEDFTIKLIDFGSAAYLERGKLFYTFCGTIE 1167
F Q+V+A+ + + ++HRDIKDENI+I KLIDFGS A L + + F GT
Sbjct: 144 FGQVVAAIQHCHSRGVVHRDIKDENILIDLRRGCAKLIDFGSGALLH-DEPYTDFDGTRV 202
Query: 1168 YCAPEVLMGNPYRGPELEMWSLGVTLYTLVFEENPFCELEETVEAAIHPPYLVSKELMSL 1227
Y PE + + Y +WSLG+ LY +V + PF +E +EA +H P VS + +L
Sbjct: 203 YSPPEWISRHQYHALPATVWSLGILLYDMVCGDIPFERDQEILEAELHFPAHVSPDCCAL 262
Query: 1228 VSGLLQPVPERRTTLEKLVTDPWVTQP 1254
+ L P P R +LE+++ DPW+ P
Sbjct: 263 IRRCLAPKPSSRPSLEEILLDPWMQTP 289
>gi|23503303 serine/threonine-protein kinase NIM1 [Homo sapiens]
Length = 436
Score = 137 bits (344), Expect = 9e-32
Identities = 83/260 (31%), Positives = 138/260 (53%), Gaps = 15/260 (5%)
Query: 999 YSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKV-TLEIAILS 1057
Y +GSG F V + ++V +K + K K+ D K ++ + EI+ +
Sbjct: 74 YRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKL-------DQKTQRLLSREISSME 126
Query: 1058 RVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQLVSAVG 1117
++ H NII++ ++ E LVME G G +LF I +L EP + IF Q+VSAV
Sbjct: 127 KLHHPNIIRLYEVVETLSKLHLVMEYAGGG-ELFGKISTEGKLSEPESKLIFSQIVSAVK 185
Query: 1118 YLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGKLFYTFCGTIEYCAPEVLMGN 1177
++ IIHRD+K EN+ + +K+ DFG + ++G++ TFCG+ Y APE+
Sbjct: 186 HMHENQIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDE 245
Query: 1178 PYRGPELEMWSLGVTLYTLVFEENPF-----CELEETV-EAAIHPPYLVSKELMSLVSGL 1231
Y G +++W+LGV LY +V PF +L++++ E P VS+ L+ G+
Sbjct: 246 HYIGIYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGV 305
Query: 1232 LQPVPERRTTLEKLVTDPWV 1251
LQ +P R ++ ++ D W+
Sbjct: 306 LQQIPTERYGIDCIMNDEWM 325
>gi|116256471 SNF1-like kinase [Homo sapiens]
Length = 783
Score = 135 bits (341), Expect = 2e-31
Identities = 85/274 (31%), Positives = 137/274 (50%), Gaps = 19/274 (6%)
Query: 990 ACEGEYSQK------YSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIED 1043
A +G+ QK Y LG G F V A + +V +K I K + ++
Sbjct: 12 AGQGQGQQKPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTR------LDS 65
Query: 1044 PKLGKVTLEIAILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEP 1103
L K+ E+ ++ + H +IIK+ + E + +V E +G ++F ++ + L E
Sbjct: 66 SNLEKIYREVQLMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNG-EMFDYLTSNGHLSEN 124
Query: 1104 LASYIFRQLVSAVGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGKLFYTFC 1163
A F Q++SAV Y I+HRD+K EN+++ + IKL DFG + + G+ T+C
Sbjct: 125 EARKKFWQILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLADFGFGNFYKSGEPLSTWC 184
Query: 1164 GTIEYCAPEVLMGNPYRGPELEMWSLGVTLYTLVFEENPF------CELEETVEAAIHPP 1217
G+ Y APEV G Y GP+L++WSLGV LY LV PF + +E P
Sbjct: 185 GSPPYAAPEVFEGKEYEGPQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIP 244
Query: 1218 YLVSKELMSLVSGLLQPVPERRTTLEKLVTDPWV 1251
+ +S++ SL+ +L P RR T+ ++ W+
Sbjct: 245 FFMSQDCESLIRRMLVVDPARRITIAQIRQHRWM 278
>gi|94557301 protein kinase, AMP-activated, alpha 1 catalytic subunit
isoform 1 [Homo sapiens]
Length = 559
Score = 134 bits (338), Expect = 4e-31
Identities = 82/266 (30%), Positives = 137/266 (51%), Gaps = 14/266 (5%)
Query: 1005 LGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVTLEIAILSRVEHANI 1064
LG G FG V + +V VK + ++K+ +GK+ EI L H +I
Sbjct: 33 LGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSL-----DVVGKIRREIQNLKLFRHPHI 87
Query: 1065 IKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQLVSAVGYLRLKDI 1124
IK+ + +VME + SG +LF +I ++ RLDE + +F+Q++S V Y +
Sbjct: 88 IKLYQVISTPSDIFMVME-YVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMV 146
Query: 1125 IHRDIKDENIVIAEDFTIKLIDFGSAAYLERGKLFYTFCGTIEYCAPEVLMGNPYRGPEL 1184
+HRD+K EN+++ K+ DFG + + G+ T CG+ Y APEV+ G Y GPE+
Sbjct: 147 VHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEV 206
Query: 1185 EMWSLGVTLYTLVFEENPFCE------LEETVEAAIHPPYLVSKELMSLVSGLLQPVPER 1238
++WS GV LY L+ PF + ++ + + P ++ ++SL+ +LQ P +
Sbjct: 207 DIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMK 266
Query: 1239 RTTLEKLVTDPWVTQPVNLADYTWEE 1264
R T++ + W Q +L Y + E
Sbjct: 267 RATIKDIREHEWFKQ--DLPKYLFPE 290
>gi|46877068 AMP-activated protein kinase alpha 2 catalytic subunit
[Homo sapiens]
Length = 552
Score = 134 bits (338), Expect = 4e-31
Identities = 84/266 (31%), Positives = 140/266 (52%), Gaps = 14/266 (5%)
Query: 1005 LGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVTLEIAILSRVEHANI 1064
LG G FG V + +V VK + ++K+ +GK+ EI L H +I
Sbjct: 22 LGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSL-----DVVGKIKREIQNLKLFRHPHI 76
Query: 1065 IKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQLVSAVGYLRLKDI 1124
IK+ + F +VME + SG +LF +I +H R++E A +F+Q++SAV Y +
Sbjct: 77 IKLYQVISTPTDFFMVME-YVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMV 135
Query: 1125 IHRDIKDENIVIAEDFTIKLIDFGSAAYLERGKLFYTFCGTIEYCAPEVLMGNPYRGPEL 1184
+HRD+K EN+++ K+ DFG + + G+ T CG+ Y APEV+ G Y GPE+
Sbjct: 136 VHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEV 195
Query: 1185 EMWSLGVTLY-----TLVFEENPFCELEETVEAAI-HPPYLVSKELMSLVSGLLQPVPER 1238
++WS GV LY TL F++ L + + + + P +++ + +L+ +LQ P +
Sbjct: 196 DIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVDPLK 255
Query: 1239 RTTLEKLVTDPWVTQPVNLADYTWEE 1264
R T++ + W Q +L Y + E
Sbjct: 256 RATIKDIREHEWFKQ--DLPSYLFPE 279
>gi|38569491 serine/threonine-protein kinase QSK [Homo sapiens]
Length = 1263
Score = 133 bits (334), Expect = 1e-30
Identities = 79/259 (30%), Positives = 134/259 (51%), Gaps = 13/259 (5%)
Query: 999 YSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVTLEIAILSR 1058
Y +G G F V A +V +K I K + +++ L K+ E+ I+
Sbjct: 8 YEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKTQ------LDEENLKKIFREVQIMKM 61
Query: 1059 VEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQLVSAVGY 1118
+ H +II++ + E + LV E + SG ++F + H R+ E A F+Q+V+AV +
Sbjct: 62 LCHPHIIRLYQVMETERMIYLVTE-YASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYF 120
Query: 1119 LRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGKLFYTFCGTIEYCAPEVLMGNP 1178
++I+HRD+K EN+++ + IK+ DFG + G+L T+CG+ Y APE+ G
Sbjct: 121 CHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKE 180
Query: 1179 YRGPELEMWSLGVTLYTLVFEENPF--CELE----ETVEAAIHPPYLVSKELMSLVSGLL 1232
Y GP++++WSLGV LY LV PF L+ + P+ +S E L+ +L
Sbjct: 181 YDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHML 240
Query: 1233 QPVPERRTTLEKLVTDPWV 1251
P +R ++E++ W+
Sbjct: 241 VLDPNKRLSMEQICKHKWM 259
>gi|7657214 hormonally upregulated Neu-associated kinase [Homo
sapiens]
Length = 714
Score = 128 bits (322), Expect = 3e-29
Identities = 87/261 (33%), Positives = 138/261 (52%), Gaps = 18/261 (6%)
Query: 1005 LGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVTLEIAILSRVEHANI 1064
LG G+F V + ++V +K I K++ +D ++ + E I + H NI
Sbjct: 68 LGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTK----NLRREGQIQQMIRHPNI 123
Query: 1065 IKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQLVSAVGYLRLKDI 1124
++LDI E + + LVME G +L I RL+E A RQL+SAV +L +
Sbjct: 124 TQLLDILETENSYYLVMELCPGG-NLMHKIYEKKRLEESEARRYIRQLISAVEHLHRAGV 182
Query: 1125 IHRDIKDENIVIAEDFTIKLIDFG---SAAYLERGKLFYTFCGTIEYCAPEVLMGNPYRG 1181
+HRD+K EN+++ ED IKLIDFG A L F T CG+ Y APE+L Y G
Sbjct: 183 VHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLARKKY-G 241
Query: 1182 PELEMWSLGVTLY-----TLVFEENPF---CELEETVEAAIHP-PYLVSKELMSLVSGLL 1232
P++++WS+GV +Y TL F PF ++ V+ ++P P +S +S + LL
Sbjct: 242 PKIDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKEMNPLPTQLSTGAISFLRSLL 301
Query: 1233 QPVPERRTTLEKLVTDPWVTQ 1253
+P P +R +++ + + W+ +
Sbjct: 302 EPDPVKRPNIQQALANRWLNE 322
>gi|7661974 maternal embryonic leucine zipper kinase [Homo sapiens]
Length = 651
Score = 128 bits (322), Expect = 3e-29
Identities = 80/271 (29%), Positives = 135/271 (49%), Gaps = 16/271 (5%)
Query: 994 EYSQKYSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVTLEI 1053
E + Y +G+G F V A + V +K + K + D L ++ EI
Sbjct: 6 ELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSD-------LPRIKTEI 58
Query: 1054 AILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQLV 1113
L + H +I ++ + E +V+E + G +LF +I RL E +FRQ+V
Sbjct: 59 EALKNLRHQHICQLYHVLETANKIFMVLE-YCPGGELFDYIISQDRLSEEETRVVFRQIV 117
Query: 1114 SAVGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGKLFY--TFCGTIEYCAP 1171
SAV Y+ + HRD+K EN++ E +KLIDFG A + K ++ T CG++ Y AP
Sbjct: 118 SAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDYHLQTCCGSLAYAAP 177
Query: 1172 EVLMGNPYRGPELEMWSLGVTLYTLVF------EENPFCELEETVEAAIHPPYLVSKELM 1225
E++ G Y G E ++WS+G+ LY L+ ++N ++ + P +S +
Sbjct: 178 ELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSI 237
Query: 1226 SLVSGLLQPVPERRTTLEKLVTDPWVTQPVN 1256
L+ +LQ P++R +++ L+ PW+ Q N
Sbjct: 238 LLLQQMLQVDPKKRISMKNLLNHPWIMQDYN 268
>gi|194294513 testis-specific serine kinase 2 [Homo sapiens]
Length = 358
Score = 128 bits (321), Expect = 4e-29
Identities = 91/264 (34%), Positives = 136/264 (51%), Gaps = 20/264 (7%)
Query: 1005 LGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVTLEIAILSRVEHANI 1064
LG G++ V +A + V VK I ++K D ++E + E+ IL+ V H +I
Sbjct: 18 LGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTD-FVER----FLPREMDILATVNHGSI 72
Query: 1065 IKVLDIFE-NQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQLVSAVGYLRLKD 1123
IK +IFE + G ++ME G DL FI L E +A +FRQL SAV Y D
Sbjct: 73 IKTYEIFETSDGRIYIIMELGVQG-DLLEFIKCQGALHEDVARKMFRQLSSAVKYCHDLD 131
Query: 1124 IIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGK-----LFYTFCGTIEYCAPEVLMGNP 1178
I+HRD+K EN+++ +DF IKL DFG + R L TFCG+ Y APEVL P
Sbjct: 132 IVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQSIP 191
Query: 1179 YRGPELEMWSLGVTLYTLVFEENPFCELEETVEAAIHPPYLV--------SKELMSLVSG 1230
Y+ ++WSLGV LY +V P+ + + I + V + E L+
Sbjct: 192 YQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTCECKDLIYR 251
Query: 1231 LLQPVPERRTTLEKLVTDPWVTQP 1254
+LQP +R ++++++ W+ P
Sbjct: 252 MLQPDVSQRLHIDEILSHSWLQPP 275
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 57,046,621
Number of Sequences: 37866
Number of extensions: 2888020
Number of successful extensions: 9869
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 621
Number of HSP's successfully gapped in prelim test: 178
Number of HSP's that attempted gapping in prelim test: 7688
Number of HSP's gapped (non-prelim): 1121
length of query: 1323
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1209
effective length of database: 13,930,794
effective search space: 16842329946
effective search space used: 16842329946
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.