Guide to the Human Genome
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Name: MELK Sequence: fasta or formatted (651aa) NCBI GI: 7661974
Description:

maternal embryonic leucine zipper kinase

Referenced in:

Additional Serine / Threonine Protein Kinases
Zinc Finger Proteins

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.8         31           2
 C cysteine            2.5         16           2
 D aspartate           6.0         39           3
 E glutamate           5.8         38           3
 F phenylalanine       2.8         18           1
 G glycine             4.9         32           2
 H histidine           2.8         18           2
 I isoleucine          4.8         31           2
 K lysine              9.1         59           2
 L leucine            11.2         73           4
 M methionine          2.6         17           1
 N asparagine          4.5         29           2
 P proline             4.8         31           1
 Q glutamine           4.1         27           2
 R arginine            5.1         33           2
 S serine              6.1         40           2
 T threonine           6.3         41           3
 V valine              6.3         41           2
 W tryptophan          1.4          9           1
 Y tyrosine            4.3         28           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   maternal embryonic leucine zipper kinase 
MARK3                 0.202   MAP/microtubule affinity-regulating kinase 3 isofor...
MARK3                 0.198   MAP/microtubule affinity-regulating kinase 3 isoform...
MARK3                 0.196   MAP/microtubule affinity-regulating kinase 3 isofor...
MARK3                 0.194   MAP/microtubule affinity-regulating kinase 3 isofor...
MARK2                 0.190   MAP/microtubule affinity-regulating kinase 2 isofor...
MARK2                 0.190   MAP/microtubule affinity-regulating kinase 2 isofor...
MARK2                 0.188   MAP/microtubule affinity-regulating kinase 2 isofor...
PRKAA1                0.176   protein kinase, AMP-activated, alpha 1 catalytic sub...
MARK2                 0.174   MAP/microtubule affinity-regulating kinase 2 isofor...
MARK4                 0.173   MAP/microtubule affinity-regulating kinase 4 
MARK2                 0.171   MAP/microtubule affinity-regulating kinase 2 isoform...
PRKAA2                0.171   AMP-activated protein kinase alpha 2 catalytic subun...
PRKAA1                0.168   protein kinase, AMP-activated, alpha 1 catalytic sub...
MARK1                 0.168   MAP/microtubule affinity-regulating kinase 1 
QSK                   0.164   serine/threonine-protein kinase QSK 
BRSK1                 0.160   BR serine/threonine kinase 1 
BRSK2                 0.156   BR serine/threonine kinase 2 
SIK1                  0.155   SNF1-like kinase 
SIK2                  0.154   SNF1-like kinase 2 
SNRK                  0.149   SNF related kinase 
SNRK                  0.149   SNF related kinase 
NUAK1                 0.144   AMPK-related protein kinase 5 
MGC42105              0.134   serine/threonine-protein kinase NIM1 
CAMK1D                0.132   calcium/calmodulin-dependent protein kinase ID isofor...
CAMK1D                0.132   calcium/calmodulin-dependent protein kinase ID isofo...
NUAK2                 0.132   NUAK family, SNF1-like kinase, 2 
HUNK                  0.132   hormonally upregulated Neu-associated kinase 
PSKH1                 0.121   protein serine kinase H1 
PNCK                  0.119   pregnancy upregulated non-ubiquitously expressed Ca...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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