Guide to the Human Genome
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Name: PRKAA1 Sequence: fasta or formatted (559aa) NCBI GI: 94557301
Description:

protein kinase, AMP-activated, alpha 1 catalytic subunit isoform 1

Referenced in:

Additional Serine / Threonine Protein Kinases

Other entries for this name:
alt prot [574aa] protein kinase, AMP-activated, alpha 1 catalytic subunit isoform 2
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.8         27           2
 C cysteine            2.0         11           1
 D aspartate           7.0         39           3
 E glutamate           5.9         33           3
 F phenylalanine       3.4         19           2
 G glycine             4.8         27           2
 H histidine           3.9         22           2
 I isoleucine          5.9         33           2
 K lysine              6.8         38           2
 L leucine             9.5         53           2
 M methionine          2.7         15           2
 N asparagine          3.2         18           1
 P proline             5.2         29           2
 Q glutamine           3.6         20           2
 R arginine            6.8         38           2
 S serine              8.6         48           2
 T threonine           4.5         25           1
 V valine              6.6         37           2
 W tryptophan          0.9          5           1
 Y tyrosine            3.9         22           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   protein kinase, AMP-activated, alpha 1 catalytic sub... 
PRKAA1                0.991   protein kinase, AMP-activated, alpha 1 catalytic sub...
PRKAA2                0.742   AMP-activated protein kinase alpha 2 catalytic subun...
SIK2                  0.238   SNF1-like kinase 2 
SIK1                  0.229   SNF1-like kinase 
BRSK1                 0.226   BR serine/threonine kinase 1 
BRSK2                 0.226   BR serine/threonine kinase 2 
MARK2                 0.218   MAP/microtubule affinity-regulating kinase 2 isofor...
MARK2                 0.218   MAP/microtubule affinity-regulating kinase 2 isofor...
MARK2                 0.218   MAP/microtubule affinity-regulating kinase 2 isoform...
MARK1                 0.217   MAP/microtubule affinity-regulating kinase 1 
MARK3                 0.217   MAP/microtubule affinity-regulating kinase 3 isofor...
MARK3                 0.217   MAP/microtubule affinity-regulating kinase 3 isofor...
MARK3                 0.217   MAP/microtubule affinity-regulating kinase 3 isoform...
QSK                   0.216   serine/threonine-protein kinase QSK 
MARK2                 0.216   MAP/microtubule affinity-regulating kinase 2 isofor...
MARK2                 0.216   MAP/microtubule affinity-regulating kinase 2 isofor...
MARK3                 0.214   MAP/microtubule affinity-regulating kinase 3 isofor...
MELK                  0.207   maternal embryonic leucine zipper kinase 
MARK4                 0.206   MAP/microtubule affinity-regulating kinase 4 
NUAK1                 0.200   AMPK-related protein kinase 5 
NUAK2                 0.197   NUAK family, SNF1-like kinase, 2 
SNRK                  0.172   SNF related kinase 
SNRK                  0.172   SNF related kinase 
MGC42105              0.169   serine/threonine-protein kinase NIM1 
HUNK                  0.158   hormonally upregulated Neu-associated kinase 
CAMK1D                0.140   calcium/calmodulin-dependent protein kinase ID isofor...
CAMK1D                0.140   calcium/calmodulin-dependent protein kinase ID isofo...
CAMK1                 0.136   calcium/calmodulin-dependent protein kinase I 
PNCK                  0.132   pregnancy upregulated non-ubiquitously expressed Ca...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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