Guide to the Human Genome
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Name: SIK1 Sequence: fasta or formatted (783aa) NCBI GI: 116256471
Description:

SNF1-like kinase

Referenced in:

Additional Serine / Threonine Protein Kinases

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.6         67           3
 C cysteine            2.4         19           1
 D aspartate           3.8         30           1
 E glutamate           5.5         43           3
 F phenylalanine       3.6         28           2
 G glycine             8.0         63           2
 H histidine           2.3         18           2
 I isoleucine          3.2         25           2
 K lysine              3.1         24           2
 L leucine            12.6         99           3
 M methionine          1.8         14           1
 N asparagine          1.9         15           1
 P proline             8.9         70           3
 Q glutamine           6.4         50           2
 R arginine            6.0         47           2
 S serine              8.6         67           2
 T threonine           5.2         41           2
 V valine              5.2         41           2
 W tryptophan          0.8          6           1
 Y tyrosine            2.0         16           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   SNF1-like kinase 
SIK2                  0.362   SNF1-like kinase 2 
QSK                   0.247   serine/threonine-protein kinase QSK 
MARK1                 0.217   MAP/microtubule affinity-regulating kinase 1 
MARK2                 0.215   MAP/microtubule affinity-regulating kinase 2 isofor...
MARK2                 0.215   MAP/microtubule affinity-regulating kinase 2 isofor...
MARK2                 0.215   MAP/microtubule affinity-regulating kinase 2 isofor...
MARK2                 0.215   MAP/microtubule affinity-regulating kinase 2 isofor...
MARK2                 0.215   MAP/microtubule affinity-regulating kinase 2 isoform...
MARK4                 0.213   MAP/microtubule affinity-regulating kinase 4 
MARK3                 0.210   MAP/microtubule affinity-regulating kinase 3 isofor...
MARK3                 0.209   MAP/microtubule affinity-regulating kinase 3 isofor...
MARK3                 0.209   MAP/microtubule affinity-regulating kinase 3 isofor...
MARK3                 0.209   MAP/microtubule affinity-regulating kinase 3 isoform...
BRSK1                 0.170   BR serine/threonine kinase 1 
BRSK2                 0.169   BR serine/threonine kinase 2 
SNRK                  0.168   SNF related kinase 
SNRK                  0.168   SNF related kinase 
PRKAA1                0.164   protein kinase, AMP-activated, alpha 1 catalytic sub...
PRKAA2                0.164   AMP-activated protein kinase alpha 2 catalytic subun...
PRKAA1                0.158   protein kinase, AMP-activated, alpha 1 catalytic sub...
MGC42105              0.147   serine/threonine-protein kinase NIM1 
NUAK1                 0.143   AMPK-related protein kinase 5 
NUAK2                 0.138   NUAK family, SNF1-like kinase, 2 
MELK                  0.131   maternal embryonic leucine zipper kinase 
TSSK1B                0.116   testis-specific serine kinase 1 
TSSK2                 0.111   testis-specific serine kinase 2 
HUNK                  0.110   hormonally upregulated Neu-associated kinase 
TSSK3                 0.103   testis-specific serine kinase 3 
DCLK3                 0.102   doublecortin-like kinase 3 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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