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Search of human proteins with 34915994
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|34915994 transducin-like enhancer protein 4 [Homo sapiens]
(773 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|34915994 transducin-like enhancer protein 4 [Homo sapiens] 1585 0.0
gi|21541824 transducin-like enhancer protein 1 [Homo sapiens] 1363 0.0
gi|157384986 transducin-like enhancer protein 3 isoform b [Homo ... 1291 0.0
gi|157384982 transducin-like enhancer protein 3 isoform a [Homo ... 1286 0.0
gi|157384984 transducin-like enhancer protein 3 isoform c [Homo ... 1266 0.0
gi|21361151 transducin-like enhancer protein 2 isoform 1 [Homo s... 998 0.0
gi|221219048 transducin-like enhancer protein 2 isoform 2 [Homo ... 867 0.0
gi|221219050 transducin-like enhancer protein 2 isoform 3 [Homo ... 789 0.0
gi|5706731 amino-terminal enhancer of split isoform b [Homo sapi... 264 3e-70
gi|39812027 amino-terminal enhancer of split isoform c [Homo sap... 258 1e-68
gi|39812019 amino-terminal enhancer of split isoform a [Homo sap... 254 3e-67
gi|221136834 transducin-like enhancer of split 6 isoform 1 [Homo... 203 4e-52
gi|13376099 transducin-like enhancer of split 6 isoform 2 [Homo ... 203 4e-52
gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens] 92 2e-18
gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens] 92 2e-18
gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens] 92 2e-18
gi|26665869 WD repeat domain 51B [Homo sapiens] 88 3e-17
gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens] 83 8e-16
gi|5729852 guanine nucleotide-binding protein, beta-5 subunit is... 82 1e-15
gi|20336270 guanine nucleotide-binding protein, beta-5 subunit i... 82 1e-15
gi|24431950 PRP4 pre-mRNA processing factor 4 homolog [Homo sapi... 73 9e-13
gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo ... 72 3e-12
gi|5174447 guanine nucleotide binding protein (G protein), beta ... 71 3e-12
gi|11055998 guanine nucleotide-binding protein, beta-4 subunit [... 71 4e-12
gi|4504053 guanine nucleotide-binding protein, beta-3 subunit [H... 70 7e-12
gi|83779014 katanin p80 subunit B 1 [Homo sapiens] 70 7e-12
gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens] 69 1e-11
gi|8923881 WD SOCS-box protein 2 [Homo sapiens] 69 2e-11
gi|21071067 TBP-associated factor 5 [Homo sapiens] 68 4e-11
gi|20143912 WD repeat and SOCS box-containing 1 isoform 2 [Homo ... 68 4e-11
>gi|34915994 transducin-like enhancer protein 4 [Homo sapiens]
Length = 773
Score = 1585 bits (4103), Expect = 0.0
Identities = 773/773 (100%), Positives = 773/773 (100%)
Query: 1 MIRDLSKMYPQTRHPAPHQPAQPFKFTISESCDRIKEEFQFLQAQYHSLKLECEKLASEK 60
MIRDLSKMYPQTRHPAPHQPAQPFKFTISESCDRIKEEFQFLQAQYHSLKLECEKLASEK
Sbjct: 1 MIRDLSKMYPQTRHPAPHQPAQPFKFTISESCDRIKEEFQFLQAQYHSLKLECEKLASEK 60
Query: 61 TEMQRHYVMYYEMSYGLNIEMHKQAEIVKRLNAICAQVIPFLSQEHQQQVVQAVERAKQV 120
TEMQRHYVMYYEMSYGLNIEMHKQAEIVKRLNAICAQVIPFLSQEHQQQVVQAVERAKQV
Sbjct: 61 TEMQRHYVMYYEMSYGLNIEMHKQAEIVKRLNAICAQVIPFLSQEHQQQVVQAVERAKQV 120
Query: 121 TMAELNAIIGQQLQAQHLSHGHGLPVPLTPHPSGLQPPAIPPIGSSAGLLALSSALGGQS 180
TMAELNAIIGQQLQAQHLSHGHGLPVPLTPHPSGLQPPAIPPIGSSAGLLALSSALGGQS
Sbjct: 121 TMAELNAIIGQQLQAQHLSHGHGLPVPLTPHPSGLQPPAIPPIGSSAGLLALSSALGGQS 180
Query: 181 HLPIKDEKKHHDNDHQRDRDSIKSSSVSPSASFRGAEKHRNSADYSSESKKQKTEEKEIA 240
HLPIKDEKKHHDNDHQRDRDSIKSSSVSPSASFRGAEKHRNSADYSSESKKQKTEEKEIA
Sbjct: 181 HLPIKDEKKHHDNDHQRDRDSIKSSSVSPSASFRGAEKHRNSADYSSESKKQKTEEKEIA 240
Query: 241 ARYDSDGEKSDDNLVVDVSNEDPSSPRGSPAHSPRENGLDKTRLLKKDAPISPASIASSS 300
ARYDSDGEKSDDNLVVDVSNEDPSSPRGSPAHSPRENGLDKTRLLKKDAPISPASIASSS
Sbjct: 241 ARYDSDGEKSDDNLVVDVSNEDPSSPRGSPAHSPRENGLDKTRLLKKDAPISPASIASSS 300
Query: 301 STPSSKSKELSLNEKSTTPVSKSNTPTPRTDAPTPGSNSTPGLRPVPGKPPGVDPLASSL 360
STPSSKSKELSLNEKSTTPVSKSNTPTPRTDAPTPGSNSTPGLRPVPGKPPGVDPLASSL
Sbjct: 301 STPSSKSKELSLNEKSTTPVSKSNTPTPRTDAPTPGSNSTPGLRPVPGKPPGVDPLASSL 360
Query: 361 RTPMAVPCPYPTPFGIVPHAGMNGELTSPGAAYAGLHNISPQMSAAAAAAAAAAAYGRSP 420
RTPMAVPCPYPTPFGIVPHAGMNGELTSPGAAYAGLHNISPQMSAAAAAAAAAAAYGRSP
Sbjct: 361 RTPMAVPCPYPTPFGIVPHAGMNGELTSPGAAYAGLHNISPQMSAAAAAAAAAAAYGRSP 420
Query: 421 VVGFDPHHHMRVPAIPPNLTGIPGGKPAYSFHVSADGQMQPVPFPPDALIGPGIPRHARQ 480
VVGFDPHHHMRVPAIPPNLTGIPGGKPAYSFHVSADGQMQPVPFPPDALIGPGIPRHARQ
Sbjct: 421 VVGFDPHHHMRVPAIPPNLTGIPGGKPAYSFHVSADGQMQPVPFPPDALIGPGIPRHARQ 480
Query: 481 INTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIRSCR 540
INTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIRSCR
Sbjct: 481 INTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIRSCR 540
Query: 541 LLPDGRTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGN 600
LLPDGRTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGN
Sbjct: 541 LLPDGRTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGN 600
Query: 601 IAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFT 660
IAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFT
Sbjct: 601 IAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFT 660
Query: 661 SQIFSLGYCPTGEWLAVGMENSNVEVLHVTKPDKYQLHLHESCVLSLKFAHCGKWFVSTG 720
SQIFSLGYCPTGEWLAVGMENSNVEVLHVTKPDKYQLHLHESCVLSLKFAHCGKWFVSTG
Sbjct: 661 SQIFSLGYCPTGEWLAVGMENSNVEVLHVTKPDKYQLHLHESCVLSLKFAHCGKWFVSTG 720
Query: 721 KDNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIVTGSGDKKATVYEVIY 773
KDNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIVTGSGDKKATVYEVIY
Sbjct: 721 KDNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIVTGSGDKKATVYEVIY 773
>gi|21541824 transducin-like enhancer protein 1 [Homo sapiens]
Length = 770
Score = 1363 bits (3529), Expect = 0.0
Identities = 668/772 (86%), Positives = 710/772 (91%), Gaps = 8/772 (1%)
Query: 8 MYPQTRHPAPHQPA-QPFKFTISESCDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRH 66
M+PQ+RHP PHQ A QPFKFTI ES DRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRH
Sbjct: 1 MFPQSRHPTPHQAAGQPFKFTIPESLDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRH 60
Query: 67 YVMYYEMSYGLNIEMHKQAEIVKRLNAICAQVIPFLSQEHQQQVVQAVERAKQVTMAELN 126
YVMYYEMSYGLNIEMHKQ EI KRLN ICAQVIPFLSQEHQQQV QAVERAKQVTMAELN
Sbjct: 61 YVMYYEMSYGLNIEMHKQTEIAKRLNTICAQVIPFLSQEHQQQVAQAVERAKQVTMAELN 120
Query: 127 AIIGQQ-LQAQHLSHGHGLPVPLTPHPSGLQPPAIPPIGSSAGLLALSSALGGQSHLPIK 185
AIIGQQ LQAQHLSHGHG PVPLTPHPSGLQPP IPP+G SAGLLALSSAL GQSHL IK
Sbjct: 121 AIIGQQQLQAQHLSHGHGPPVPLTPHPSGLQPPGIPPLGGSAGLLALSSALSGQSHLAIK 180
Query: 186 DEKKHHDNDHQRDRDSIKSSSVSPSASFRGAEKHRNSADYSSESKKQKTEEKEIAARYDS 245
D+KKHHD +H RDR+ S+S+ S RG +K RN ++S++ KK+K ++K+ ++ YDS
Sbjct: 181 DDKKHHDAEHHRDREPGTSNSLLVPDSLRGTDKRRNGPEFSNDIKKRKVDDKD-SSHYDS 239
Query: 246 DGEKSDDNLVVDVSNEDPSSPRGSPAHSPRENGLDKTRLLKKDAPISPASIASSSSTPSS 305
DG+KSDDNLVVDVSNEDPSSPR SPAHSPRENG+DK RLLKKDA SPAS ASS+S+ S
Sbjct: 240 DGDKSDDNLVVDVSNEDPSSPRASPAHSPRENGIDKNRLLKKDASSSPASTASSASSTSL 299
Query: 306 KSKELSLNEKSTTPVSKSNTPTPRTDAPTPGSNSTPGLRPVPGKPPGVDPL----ASSLR 361
KSKE+SL+EK++TPV KS+TPTPR+D PTPG+++TPGLRP GKPP +DPL A+ LR
Sbjct: 300 KSKEMSLHEKASTPVLKSSTPTPRSDMPTPGTSATPGLRPGLGKPPAIDPLVNQAAAGLR 359
Query: 362 TPMAVPCPYPTPFGIVPHAGMNGELTSPGAAYAGLHNISPQMSAAAAAAAAAAAYGRSPV 421
TP+AVP PYP PFG+VPHAGMNGELTSPGAAYA LHN+SPQMSAAAAAAA A YGRSP+
Sbjct: 360 TPLAVPGPYPAPFGMVPHAGMNGELTSPGAAYASLHNMSPQMSAAAAAAAVVA-YGRSPM 418
Query: 422 VGFDPHHHMRVPAIPPNLTGIPGGKPAYSFHVSADGQMQPVPFPPDALIGPGIPRHARQI 481
VGFDP HMRVP IPPNL GIPGGKPAYSFHV+ADGQMQPVPFPPDALIGPGIPRHARQI
Sbjct: 419 VGFDPPPHMRVPTIPPNLAGIPGGKPAYSFHVTADGQMQPVPFPPDALIGPGIPRHARQI 478
Query: 482 NTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIRSCRL 541
NTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIRSC+L
Sbjct: 479 NTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIRSCKL 538
Query: 542 LPDGRTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNI 601
LPDG TLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNI
Sbjct: 539 LPDGCTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNI 598
Query: 602 AVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTS 661
AVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTS
Sbjct: 599 AVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTS 658
Query: 662 QIFSLGYCPTGEWLAVGMENSNVEVLHVTKPDKYQLHLHESCVLSLKFAHCGKWFVSTGK 721
QIFSLGYCPTGEWLAVGME+SNVEVLHV KPDKYQLHLHESCVLSLKFA+CGKWFVSTGK
Sbjct: 659 QIFSLGYCPTGEWLAVGMESSNVEVLHVNKPDKYQLHLHESCVLSLKFAYCGKWFVSTGK 718
Query: 722 DNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIVTGSGDKKATVYEVIY 773
DNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIVTGSGDKKATVYEVIY
Sbjct: 719 DNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIVTGSGDKKATVYEVIY 770
>gi|157384986 transducin-like enhancer protein 3 isoform b [Homo
sapiens]
Length = 769
Score = 1291 bits (3342), Expect = 0.0
Identities = 640/775 (82%), Positives = 696/775 (89%), Gaps = 15/775 (1%)
Query: 8 MYPQTRHPAPHQPAQP-FKFTISESCDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRH 66
MYPQ RHPAPHQP QP FKFT++ESCDRIK+EFQFLQAQYHSLK+E +KLA+EKTEMQRH
Sbjct: 1 MYPQGRHPAPHQPGQPGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYDKLANEKTEMQRH 60
Query: 67 YVMYYEMSYGLNIEMHKQAEIVKRLNAICAQVIPFLSQEHQQQVVQAVERAKQVTMAELN 126
YVMYYEMSYGLNIEMHKQ EI KRLN I AQ++PFLSQEHQQQV QAVERAKQVTM ELN
Sbjct: 61 YVMYYEMSYGLNIEMHKQTEIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVTMTELN 120
Query: 127 AIIGQQ-LQAQHLSHG-HGLPVPLTPHPSGLQPPAIPPI-GSSAGLLALSSALGGQSHLP 183
AIIGQQ LQAQHLSH HG PV L PHPSGLQPP IPP+ GSS+GLLAL ALG Q+HL
Sbjct: 121 AIIGQQQLQAQHLSHATHGPPVQLPPHPSGLQPPGIPPVTGSSSGLLALG-ALGSQAHLT 179
Query: 184 IKDEKKHHDNDHQRDRDSIKSSSVSPSASFRGAEKHRNSADYSSESKKQKTEEKEIAARY 243
+KDEK HH+ DH R+R+S ++SVSPS S R +EKHR SADYS E+KK+K EEK+ +RY
Sbjct: 180 VKDEKNHHELDH-RERESSANNSVSPSESLRASEKHRGSADYSMEAKKRKAEEKDSLSRY 238
Query: 244 DSDGEKSDDNLVVDVSNEDPSSPRGSPAHSPRENGLDKTRLLKKDAPISPASIASSSSTP 303
DSDG+KSDD LVVDVSNEDP++PR SPAHSP ENGLDK R LKKDAP SPAS+ASSSSTP
Sbjct: 239 DSDGDKSDD-LVVDVSNEDPATPRVSPAHSPPENGLDKARSLKKDAPTSPASVASSSSTP 297
Query: 304 SSKSKELSLNEKSTTPVSKSNTPTPRTDAPTPGSNSTPGLRPVPGKPPGVDPLASSLRTP 363
SSK+K+L N+KS+TP KSNTPTPR DAPTPG+++TPGLR +PGKPPG+DP+AS+LRTP
Sbjct: 298 SSKTKDLGHNDKSSTPGLKSNTPTPRNDAPTPGTSTTPGLRSMPGKPPGMDPIASALRTP 357
Query: 364 MAVPCPYPTPFGIVPHAGMNGELTSPGAAYAGLHNISPQMSAAAAAAAAAAAYGRSPVV- 422
+++ Y PF ++ H MNG LTSPGA YAGLHNI PQMSAAAAAAAAA YGRSP+V
Sbjct: 358 ISITSSYAAPFAMMSHHEMNGSLTSPGA-YAGLHNIPPQMSAAAAAAAAA--YGRSPMVS 414
Query: 423 ----GFDPHHHMRVPAIPPNLTGIPGGKPAYSFHVSADGQMQPVPFPPDALIGPGIPRHA 478
GFDPH MR +P +L IPGGKPAYSFHVSADGQMQPVPFP DAL GPGIPRHA
Sbjct: 415 FGAVGFDPHPPMRATGLPSSLASIPGGKPAYSFHVSADGQMQPVPFPHDALAGPGIPRHA 474
Query: 479 RQINTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIRS 538
RQINTL+HGEVVCAVTISNPTRHVYTGGKGCVK+WDIS PG+KSP+SQLDCLNRDNYIRS
Sbjct: 475 RQINTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYIRS 534
Query: 539 CRLLPDGRTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSD 598
C+LLPDGRTLIVGGEASTL+IWDLA+PTPRIKAELTSSAPACYALAISPD+KVCFSCCSD
Sbjct: 535 CKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSD 594
Query: 599 GNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHD 658
GNIAVWDLHNQTLVRQFQGHTDGASCIDIS+DGTKLWTGGLDNTVRSWDLREGRQLQQHD
Sbjct: 595 GNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHD 654
Query: 659 FTSQIFSLGYCPTGEWLAVGMENSNVEVLHVTKPDKYQLHLHESCVLSLKFAHCGKWFVS 718
FTSQIFSLGYCPTGEWLAVGME+SNVEVLH TKPDKYQLHLHESCVLSLKFA+CGKWFVS
Sbjct: 655 FTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLSLKFAYCGKWFVS 714
Query: 719 TGKDNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIVTGSGDKKATVYEVIY 773
TGKDNLLNAWRTPYGASIFQSKESSSVLSCDIS DDKYIVTGSGDKKATVYEVIY
Sbjct: 715 TGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY 769
>gi|157384982 transducin-like enhancer protein 3 isoform a [Homo
sapiens]
Length = 772
Score = 1286 bits (3328), Expect = 0.0
Identities = 640/778 (82%), Positives = 696/778 (89%), Gaps = 18/778 (2%)
Query: 8 MYPQTRHPAPHQPAQP-FKFTISESCDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRH 66
MYPQ RHPAPHQP QP FKFT++ESCDRIK+EFQFLQAQYHSLK+E +KLA+EKTEMQRH
Sbjct: 1 MYPQGRHPAPHQPGQPGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYDKLANEKTEMQRH 60
Query: 67 YVMYYEMSYGLNIEMHKQAEIVKRLNAICAQVIPFLSQEHQQQVVQAVERAKQVTMAELN 126
YVMYYEMSYGLNIEMHKQ EI KRLN I AQ++PFLSQEHQQQV QAVERAKQVTM ELN
Sbjct: 61 YVMYYEMSYGLNIEMHKQTEIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVTMTELN 120
Query: 127 AIIGQQ-LQAQHLSHG-HGLPVPLTPHPSGLQPPAIPPI-GSSAGLLALSSALGGQSHLP 183
AIIGQQ LQAQHLSH HG PV L PHPSGLQPP IPP+ GSS+GLLAL ALG Q+HL
Sbjct: 121 AIIGQQQLQAQHLSHATHGPPVQLPPHPSGLQPPGIPPVTGSSSGLLALG-ALGSQAHLT 179
Query: 184 IKDEKKHHDNDHQRDRDSIKSSSVSPSASFRGAEKHRNSADYSSESKKQKTEEKEIAARY 243
+KDEK HH+ DH R+R+S ++SVSPS S R +EKHR SADYS E+KK+K EEK+ +RY
Sbjct: 180 VKDEKNHHELDH-RERESSANNSVSPSESLRASEKHRGSADYSMEAKKRKAEEKDSLSRY 238
Query: 244 DSDGEKSDDNLVVDVSNEDPSSPRGSPAHSPRENGLDKTRLLKKDAPISPASIASSSSTP 303
DSDG+KSDD LVVDVSNEDP++PR SPAHSP ENGLDK R LKKDAP SPAS+ASSSSTP
Sbjct: 239 DSDGDKSDD-LVVDVSNEDPATPRVSPAHSPPENGLDKARSLKKDAPTSPASVASSSSTP 297
Query: 304 SSKSKELSLNEKSTTPVSKSNTPTPRTDAPTPGSNSTPGLRPVPGKPPGVDPL---ASSL 360
SSK+K+L N+KS+TP KSNTPTPR DAPTPG+++TPGLR +PGKPPG+DP+ AS+L
Sbjct: 298 SSKTKDLGHNDKSSTPGLKSNTPTPRNDAPTPGTSTTPGLRSMPGKPPGMDPIGIMASAL 357
Query: 361 RTPMAVPCPYPTPFGIVPHAGMNGELTSPGAAYAGLHNISPQMSAAAAAAAAAAAYGRSP 420
RTP+++ Y PF ++ H MNG LTSPGA YAGLHNI PQMSAAAAAAAAA YGRSP
Sbjct: 358 RTPISITSSYAAPFAMMSHHEMNGSLTSPGA-YAGLHNIPPQMSAAAAAAAAA--YGRSP 414
Query: 421 VV-----GFDPHHHMRVPAIPPNLTGIPGGKPAYSFHVSADGQMQPVPFPPDALIGPGIP 475
+V GFDPH MR +P +L IPGGKPAYSFHVSADGQMQPVPFP DAL GPGIP
Sbjct: 415 MVSFGAVGFDPHPPMRATGLPSSLASIPGGKPAYSFHVSADGQMQPVPFPHDALAGPGIP 474
Query: 476 RHARQINTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNY 535
RHARQINTL+HGEVVCAVTISNPTRHVYTGGKGCVK+WDIS PG+KSP+SQLDCLNRDNY
Sbjct: 475 RHARQINTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNY 534
Query: 536 IRSCRLLPDGRTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSC 595
IRSC+LLPDGRTLIVGGEASTL+IWDLA+PTPRIKAELTSSAPACYALAISPD+KVCFSC
Sbjct: 535 IRSCKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSC 594
Query: 596 CSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQ 655
CSDGNIAVWDLHNQTLVRQFQGHTDGASCIDIS+DGTKLWTGGLDNTVRSWDLREGRQLQ
Sbjct: 595 CSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQ 654
Query: 656 QHDFTSQIFSLGYCPTGEWLAVGMENSNVEVLHVTKPDKYQLHLHESCVLSLKFAHCGKW 715
QHDFTSQIFSLGYCPTGEWLAVGME+SNVEVLH TKPDKYQLHLHESCVLSLKFA+CGKW
Sbjct: 655 QHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLSLKFAYCGKW 714
Query: 716 FVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIVTGSGDKKATVYEVIY 773
FVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDIS DDKYIVTGSGDKKATVYEVIY
Sbjct: 715 FVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY 772
>gi|157384984 transducin-like enhancer protein 3 isoform c [Homo
sapiens]
Length = 760
Score = 1266 bits (3275), Expect = 0.0
Identities = 633/775 (81%), Positives = 687/775 (88%), Gaps = 24/775 (3%)
Query: 8 MYPQTRHPAPHQPAQP-FKFTISESCDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRH 66
MYPQ RHPAPHQP QP FKFT++ESCDRIK+EFQFLQAQYHSLK+E +KLA+EKTEMQRH
Sbjct: 1 MYPQGRHPAPHQPGQPGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYDKLANEKTEMQRH 60
Query: 67 YVMYYEMSYGLNIEMHKQAEIVKRLNAICAQVIPFLSQEHQQQVVQAVERAKQVTMAELN 126
YVMYYEMSYGLNIEMHKQ EI KRLN I AQ++PFLSQEHQQQV QAVERAKQVTM ELN
Sbjct: 61 YVMYYEMSYGLNIEMHKQTEIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVTMTELN 120
Query: 127 AIIGQQ-LQAQHLSHG-HGLPVPLTPHPSGLQPPAIPPI-GSSAGLLALSSALGGQSHLP 183
AIIGQQ LQAQHLSH HG PV L PHPSGLQPP IPP+ GSS+GLLAL ALG Q+HL
Sbjct: 121 AIIGQQQLQAQHLSHATHGPPVQLPPHPSGLQPPGIPPVTGSSSGLLALG-ALGSQAHLT 179
Query: 184 IKDEKKHHDNDHQRDRDSIKSSSVSPSASFRGAEKHRNSADYSSESKKQKTEEKEIAARY 243
+KDEK HH+ DH R+R+S ++SVSPS S R +EKHR SADYS E+KK+K EEK+ +RY
Sbjct: 180 VKDEKNHHELDH-RERESSANNSVSPSESLRASEKHRGSADYSMEAKKRKAEEKDSLSRY 238
Query: 244 DSDGEKSDDNLVVDVSNEDPSSPRGSPAHSPRENGLDKTRLLKKDAPISPASIASSSSTP 303
DSDG+KSDD LVVDVSNEDP++PR SPAHSP ENGLDK R LKKDAP SPAS+ASSSSTP
Sbjct: 239 DSDGDKSDD-LVVDVSNEDPATPRVSPAHSPPENGLDKARSLKKDAPTSPASVASSSSTP 297
Query: 304 SSKSKELSLNEKSTTPVSKSNTPTPRTDAPTPGSNSTPGLRPVPGKPPGVDPLASSLRTP 363
SSK+K+L N+KS+TP KSNTPTPR DAPTPG+++TPGLR +P AS+LRTP
Sbjct: 298 SSKTKDLGHNDKSSTPGLKSNTPTPRNDAPTPGTSTTPGLRSMP---------ASALRTP 348
Query: 364 MAVPCPYPTPFGIVPHAGMNGELTSPGAAYAGLHNISPQMSAAAAAAAAAAAYGRSPVV- 422
+++ Y PF ++ H MNG LTSPGA YAGLHNI PQMSAAAAAAAAA YGRSP+V
Sbjct: 349 ISITSSYAAPFAMMSHHEMNGSLTSPGA-YAGLHNIPPQMSAAAAAAAAA--YGRSPMVS 405
Query: 423 ----GFDPHHHMRVPAIPPNLTGIPGGKPAYSFHVSADGQMQPVPFPPDALIGPGIPRHA 478
GFDPH MR +P +L IPGGKPAYSFHVSADGQMQPVPFP DAL GPGIPRHA
Sbjct: 406 FGAVGFDPHPPMRATGLPSSLASIPGGKPAYSFHVSADGQMQPVPFPHDALAGPGIPRHA 465
Query: 479 RQINTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIRS 538
RQINTL+HGEVVCAVTISNPTRHVYTGGKGCVK+WDIS PG+KSP+SQLDCLNRDNYIRS
Sbjct: 466 RQINTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYIRS 525
Query: 539 CRLLPDGRTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSD 598
C+LLPDGRTLIVGGEASTL+IWDLA+PTPRIKAELTSSAPACYALAISPD+KVCFSCCSD
Sbjct: 526 CKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSD 585
Query: 599 GNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHD 658
GNIAVWDLHNQTLVRQFQGHTDGASCIDIS+DGTKLWTGGLDNTVRSWDLREGRQLQQHD
Sbjct: 586 GNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHD 645
Query: 659 FTSQIFSLGYCPTGEWLAVGMENSNVEVLHVTKPDKYQLHLHESCVLSLKFAHCGKWFVS 718
FTSQIFSLGYCPTGEWLAVGME+SNVEVLH TKPDKYQLHLHESCVLSLKFA+CGKWFVS
Sbjct: 646 FTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLSLKFAYCGKWFVS 705
Query: 719 TGKDNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIVTGSGDKKATVYEVIY 773
TGKDNLLNAWRTPYGASIFQSKESSSVLSCDIS DDKYIVTGSGDKKATVYEVIY
Sbjct: 706 TGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY 760
>gi|21361151 transducin-like enhancer protein 2 isoform 1 [Homo
sapiens]
Length = 743
Score = 998 bits (2580), Expect = 0.0
Identities = 522/774 (67%), Positives = 608/774 (78%), Gaps = 39/774 (5%)
Query: 8 MYPQTRHPAPHQPAQPFKFTISESCDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHY 67
MYPQ RHP P Q QPFKF+I E CDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHY
Sbjct: 1 MYPQGRHPTPLQSGQPFKFSILEICDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHY 60
Query: 68 VMYYEMSYGLNIEMHKQAEIVKRLNAICAQVIPFLSQEHQQQVVQAVERAKQVTMAELNA 127
VMYYEMSYGLNIEMHKQAEIVKRL+ ICAQ+IPFL+QEHQQQV+QAVERAKQVT+ ELN+
Sbjct: 61 VMYYEMSYGLNIEMHKQAEIVKRLSGICAQIIPFLTQEHQQQVLQAVERAKQVTVGELNS 120
Query: 128 IIGQQLQAQHLSHGHGLPVPLTPHPSGLQPPAIPPIGSSAGLLALSSALGGQSHLP--IK 185
+IGQQLQ LSH H PVPLTP P+GL GS+ GLLALS AL Q+ L +K
Sbjct: 121 LIGQQLQP--LSH-HAPPVPLTPRPAGLVG------GSATGLLALSGALAAQAQLAAAVK 171
Query: 186 DEKKHHDNDHQR-DRDSIKSSSVSPSASFRGAEKHRNSADYSSESKKQKTEEKEIAARYD 244
+++ + + R +R +S+S SP S E+ R S KQ+ +EKE + Y+
Sbjct: 172 EDRAGVEAEGSRVERAPSRSASPSPPESL--VEEERPSGP--GGGGKQRADEKEPSGPYE 227
Query: 245 SDGEKSDDNLVVDVSNEDPSSPRGSPAHSPRENGLDKTRLL---KKDAPISPASIASSSS 301
SD +KSD NLVVD ED S SPA +P K + ++D SPAS+ASS
Sbjct: 228 SDEDKSDYNLVVD---EDQPSEPPSPATTP----CGKVPICIPARRDLVDSPASLASSLG 280
Query: 302 TPSSKSKELSLNE-KSTTPVSKSNTPTPRTDAPTPGSNSTPGLRPVPGKP-PGVDPLASS 359
+P ++KEL LN+ ++TP SKS +P DA TPG +S L + KP P D +A
Sbjct: 281 SPLPRAKELILNDLPASTPASKSCDSSPPQDASTPGPSSASHLCQLAAKPAPSTDSVA-- 338
Query: 360 LRTPMAVPCPYPTPFGIVPHAGMNGELTSPGAAYAGLHNISPQMSAAAAAAAAAAAYGRS 419
LR+P+ + P+ T F + H+ +NG+L+ P ++Y LH +SPQ+S++ YGRS
Sbjct: 339 LRSPLTLSSPFTTSFSLGSHSTLNGDLSVP-SSYVSLH-LSPQVSSSVV-------YGRS 389
Query: 420 PVVGFDPHHHMRVPAIPPNLTGIPGGKPAYSFHVSADGQMQPVPFPPDALIGPGIPRHAR 479
PV+ F+ H H+R ++ +L IPGGKPAYSFHVSADGQMQPVPFP DAL+G GIPRHAR
Sbjct: 390 PVMAFESHPHLRGSSVSSSLPSIPGGKPAYSFHVSADGQMQPVPFPSDALVGAGIPRHAR 449
Query: 480 QINTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIRSC 539
Q++TL HGEVVCAVTIS T+HVYTGGKGCVKVWD+ PG K+PV+QLDCLNRDNYIRSC
Sbjct: 450 QLHTLAHGEVVCAVTISGSTQHVYTGGKGCVKVWDVGQPGAKTPVAQLDCLNRDNYIRSC 509
Query: 540 RLLPDGRTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDG 599
+LLPDGR+LIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALA+SPD+KVCFSCCSDG
Sbjct: 510 KLLPDGRSLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDG 569
Query: 600 NIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDF 659
NI VWDL NQT+VRQFQGHTDGASCIDIS+ GT+LWTGGLDNTVR WDLREGRQLQQHDF
Sbjct: 570 NIVVWDLQNQTMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQHDF 629
Query: 660 TSQIFSLGYCPTGEWLAVGMENSNVEVLHVTKPDKYQLHLHESCVLSLKFAHCGKWFVST 719
+SQIFSLG+CP +WLAVGME+SNVE+LHV KP+KYQLHLHESCVLSLKFA CG+WFVST
Sbjct: 630 SSQIFSLGHCPNQDWLAVGMESSNVEILHVRKPEKYQLHLHESCVLSLKFASCGRWFVST 689
Query: 720 GKDNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIVTGSGDKKATVYEVIY 773
GKDNLLNAWRTPYGASIFQSKESSSVLSCDIS ++KYIVTGSGDKKATVYEV+Y
Sbjct: 690 GKDNLLNAWRTPYGASIFQSKESSSVLSCDISRNNKYIVTGSGDKKATVYEVVY 743
>gi|221219048 transducin-like enhancer protein 2 isoform 2 [Homo
sapiens]
Length = 706
Score = 867 bits (2240), Expect = 0.0
Identities = 460/711 (64%), Positives = 543/711 (76%), Gaps = 38/711 (5%)
Query: 10 PQTRHPAPHQPAQPFKFTISESCDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVM 69
P + P Q QPFKF+I E CDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVM
Sbjct: 16 PASGLQTPLQSGQPFKFSILEICDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVM 75
Query: 70 YYEMSYGLNIEMHKQAEIVKRLNAICAQVIPFLSQEHQQQVVQAVERAKQVTMAELNAII 129
YYEMSYGLNIEMHKQAEIVKRL+ ICAQ+IPFL+QEHQQQV+QAVERAKQVT+ ELN++I
Sbjct: 76 YYEMSYGLNIEMHKQAEIVKRLSGICAQIIPFLTQEHQQQVLQAVERAKQVTVGELNSLI 135
Query: 130 GQQLQAQHLSHGHGLPVPLTPHPSGLQPPAIPPIGSSAGLLALSSALGGQSHLP--IKDE 187
GQQ Q Q LSH H PVPLTP P+GL GS+ GLLALS AL Q+ L +K++
Sbjct: 136 GQQ-QLQPLSH-HAPPVPLTPRPAGLVG------GSATGLLALSGALAAQAQLAAAVKED 187
Query: 188 KKHHDNDHQR-DRDSIKSSSVSPSASFRGAEKHRNSADYSSESKKQKTEEKEIAARYDSD 246
+ + + R +R +S+S SP S E+ R S KQ+ +EKE + Y+SD
Sbjct: 188 RAGVEAEGSRVERAPSRSASPSPPESL--VEEERPSGP--GGGGKQRADEKEPSGPYESD 243
Query: 247 GEKSDDNLVVDVSNEDPSSPRGSPAHSPRENGLDKTRLL---KKDAPISPASIASSSSTP 303
+KSD NLVVD ED S SPA +P K + ++D SPAS+ASS +P
Sbjct: 244 EDKSDYNLVVD---EDQPSEPPSPATTP----CGKVPICIPARRDLVDSPASLASSLGSP 296
Query: 304 SSKSKELSLNE-KSTTPVSKSNTPTPRTDAPTPGSNSTPGLRPVPGKP-PGVDPLASSLR 361
++KEL LN+ ++TP SKS +P DA TPG +S L + KP P D +A LR
Sbjct: 297 LPRAKELILNDLPASTPASKSCDSSPPQDASTPGPSSASHLCQLAAKPAPSTDSVA--LR 354
Query: 362 TPMAVPCPYPTPFGIVPHAGMNGELTSPGAAYAGLHNISPQMSAAAAAAAAAAAYGRSPV 421
+P+ + P+ T F + H+ +NG+L+ P ++Y LH +SPQ+S++ YGRSPV
Sbjct: 355 SPLTLSSPFTTSFSLGSHSTLNGDLSVP-SSYVSLH-LSPQVSSSVV-------YGRSPV 405
Query: 422 VGFDPHHHMRVPAIPPNLTGIPGGKPAYSFHVSADGQMQPVPFPPDALIGPGIPRHARQI 481
+ F+ H H+R ++ +L IPGGKPAYSFHVSADGQMQPVPFP DAL+G GIPRHARQ+
Sbjct: 406 MAFESHPHLRGSSVSSSLPSIPGGKPAYSFHVSADGQMQPVPFPSDALVGAGIPRHARQL 465
Query: 482 NTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIRSCRL 541
+TL HGEVVCAVTIS T+HVYTGGKGCVKVWD+ PG K+PV+QLDCLNRDNYIRSC+L
Sbjct: 466 HTLAHGEVVCAVTISGSTQHVYTGGKGCVKVWDVGQPGAKTPVAQLDCLNRDNYIRSCKL 525
Query: 542 LPDGRTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNI 601
LPDGR+LIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALA+SPD+KVCFSCCSDGNI
Sbjct: 526 LPDGRSLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNI 585
Query: 602 AVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTS 661
VWDL NQT+VRQFQGHTDGASCIDIS+ GT+LWTGGLDNTVR WDLREGRQLQQHDF+S
Sbjct: 586 VVWDLQNQTMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQHDFSS 645
Query: 662 QIFSLGYCPTGEWLAVGMENSNVEVLHVTKPDKYQLHLHESCVLSLKFAHC 712
QIFSLG+CP +WLAVGME+SNVE+LHV KP+KYQLHLHESCVLSLKFA C
Sbjct: 646 QIFSLGHCPNQDWLAVGMESSNVEILHVRKPEKYQLHLHESCVLSLKFASC 696
>gi|221219050 transducin-like enhancer protein 2 isoform 3 [Homo
sapiens]
Length = 621
Score = 789 bits (2038), Expect = 0.0
Identities = 425/712 (59%), Positives = 496/712 (69%), Gaps = 92/712 (12%)
Query: 63 MQRHYVMYYEMSYGLNIEMHKQAEIVKRLNAICAQVIPFLSQEHQQQVVQAVERAKQVTM 122
MQRHYVMYYEMSYGLNIEMHKQAEIVKRL+ ICAQ+IPFL+QEHQQQV+QAVERAKQVT+
Sbjct: 1 MQRHYVMYYEMSYGLNIEMHKQAEIVKRLSGICAQIIPFLTQEHQQQVLQAVERAKQVTV 60
Query: 123 AELNAIIGQQLQAQHLSHGHGLPVPLTPHPSGLQPPAIPPIGSSAGLLALSSALGGQSHL 182
ELN++IG +P P P G GG+
Sbjct: 61 GELNSLIGS----------------ASPSPPESLVEEERPSGPGG---------GGKQRA 95
Query: 183 PIKDEKKHHDNDHQRDRDSIKSSSVSPSASFRGAEKHRNSADYSSESKKQKTEEKEIAAR 242
K+ +++D + ++ PS A I AR
Sbjct: 96 DEKEPSGPYESDEDKSDYNLVVDEDQPSEPPSPATTPCGKVPIC------------IPAR 143
Query: 243 YDSDGEKSDDNLVVDVSNEDPSSPRGSPAHSPRENGLDKTRLLKKDAPISPASIASSSST 302
D +VD S +S GSP +E L+ D P +ST
Sbjct: 144 RD----------LVD-SPASLASSLGSPLPRAKE-------LILNDLP---------AST 176
Query: 303 PSSKSKELSLNEKSTTPVSKSNTPTPRTDAPTPGSNSTPGLRPVPGKP-PGVDPLASSLR 361
P+SKS + S P DA TPG +S L + KP P D +A LR
Sbjct: 177 PASKSCDSS----------------PPQDASTPGPSSASHLCQLAAKPAPSTDSVA--LR 218
Query: 362 TPMAVPCPYPTPFGIVPHAGMNGELTSPGAAYAGLHNISPQMSAAAAAAAAAAAYGRSPV 421
+P+ + P+ T F + H+ +NG+L+ P ++Y LH +SPQ+S ++ YGRSPV
Sbjct: 219 SPLTLSSPFTTSFSLGSHSTLNGDLSVP-SSYVSLH-LSPQVS-------SSVVYGRSPV 269
Query: 422 VGFDPHHHMRVPAIPPNLTGIPGGKPAYSFHVSADGQMQPVPFPPDALIGPGIPRHARQI 481
+ F+ H H+R ++ +L IPGGKPAYSFHVSADGQMQPVPFP DAL+G GIPRHARQ+
Sbjct: 270 MAFESHPHLRGSSVSSSLPSIPGGKPAYSFHVSADGQMQPVPFPSDALVGAGIPRHARQL 329
Query: 482 NTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIRSCRL 541
+TL HGEVVCAVTIS T+HVYTGGKGCVKVWD+ PG K+PV+QLDCLNRDNYIRSC+L
Sbjct: 330 HTLAHGEVVCAVTISGSTQHVYTGGKGCVKVWDVGQPGAKTPVAQLDCLNRDNYIRSCKL 389
Query: 542 LPDGRTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNI 601
LPDGR+LIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALA+SPD+KVCFSCCSDGNI
Sbjct: 390 LPDGRSLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNI 449
Query: 602 AVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTS 661
VWDL NQT+VRQFQGHTDGASCIDIS+ GT+LWTGGLDNTVR WDLREGRQLQQHDF+S
Sbjct: 450 VVWDLQNQTMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQHDFSS 509
Query: 662 QIFSLGYCPTGEWLAVGMENSNVEVLHVTKPDKYQLHLHESCVLSLKFAHCGKWFVSTGK 721
QIFSLG+CP +WLAVGME+SNVE+LHV KP+KYQLHLHESCVLSLKFA CG+WFVSTGK
Sbjct: 510 QIFSLGHCPNQDWLAVGMESSNVEILHVRKPEKYQLHLHESCVLSLKFASCGRWFVSTGK 569
Query: 722 DNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIVTGSGDKKATVYEVIY 773
DNLLNAWRTPYGASIFQSKESSSVLSCDIS ++KYIVTGSGDKKATVYEV+Y
Sbjct: 570 DNLLNAWRTPYGASIFQSKESSSVLSCDISRNNKYIVTGSGDKKATVYEVVY 621
>gi|5706731 amino-terminal enhancer of split isoform b [Homo
sapiens]
Length = 197
Score = 264 bits (674), Expect = 3e-70
Identities = 134/197 (68%), Positives = 156/197 (79%), Gaps = 2/197 (1%)
Query: 8 MYPQTRHPAPHQPAQPFKFTISESCDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHY 67
M+PQ+RH Q KFT S+SCDRIK+EFQ LQAQYHSLKLEC+KLASEK+EMQRHY
Sbjct: 2 MFPQSRHSGSSHLPQQLKFTTSDSCDRIKDEFQLLQAQYHSLKLECDKLASEKSEMQRHY 61
Query: 68 VMYYEMSYGLNIEMHKQAEIVKRLNAICAQVIPFLSQEHQQQVVQAVERAKQVTMAELNA 127
VMYYEMSYGLNIEMHKQAEIVKRLN ICAQV+P+LSQEHQQQV+ A+ERAKQVT ELN+
Sbjct: 62 VMYYEMSYGLNIEMHKQAEIVKRLNGICAQVLPYLSQEHQQQVLGAIERAKQVTAPELNS 121
Query: 128 IIGQQLQAQHLSHGHGLPVPLTPHPSGLQPPAIPPIGSSAGLLALSSALGGQSHLPIKDE 187
II QQLQA LS L +PLTP P GLQPP++P + + GLL+L SALG Q+HL K++
Sbjct: 122 IIRQQLQAHQLSQLQALALPLTPLPVGLQPPSLPAVSAGTGLLSL-SALGSQAHLS-KED 179
Query: 188 KKHHDNDHQRDRDSIKS 204
K HD D ++ D KS
Sbjct: 180 KNGHDGDTHQEDDGEKS 196
>gi|39812027 amino-terminal enhancer of split isoform c [Homo
sapiens]
Length = 196
Score = 258 bits (660), Expect = 1e-68
Identities = 133/197 (67%), Positives = 156/197 (79%), Gaps = 3/197 (1%)
Query: 8 MYPQTRHPAPHQPAQPFKFTISESCDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHY 67
M+PQ+RH Q KFT S+SCDRIK+EFQ LQAQYHSLKLEC+KLASEK+EMQRHY
Sbjct: 2 MFPQSRHSGSSHLPQQLKFTTSDSCDRIKDEFQLLQAQYHSLKLECDKLASEKSEMQRHY 61
Query: 68 VMYYEMSYGLNIEMHKQAEIVKRLNAICAQVIPFLSQEHQQQVVQAVERAKQVTMAELNA 127
VMYYEMSYGLNIEMHKQAEIVKRLN ICAQV+P+LSQEHQQQV+ A+ERAKQVT ELN+
Sbjct: 62 VMYYEMSYGLNIEMHKQAEIVKRLNGICAQVLPYLSQEHQQQVLGAIERAKQVTAPELNS 121
Query: 128 IIGQQLQAQHLSHGHGLPVPLTPHPSGLQPPAIPPIGSSAGLLALSSALGGQSHLPIKDE 187
II +QLQA LS L +PLTP P GLQPP++P + + GLL+L SALG Q+HL K++
Sbjct: 122 II-RQLQAHQLSQLQALALPLTPLPVGLQPPSLPAVSAGTGLLSL-SALGSQAHLS-KED 178
Query: 188 KKHHDNDHQRDRDSIKS 204
K HD D ++ D KS
Sbjct: 179 KNGHDGDTHQEDDGEKS 195
>gi|39812019 amino-terminal enhancer of split isoform a [Homo
sapiens]
Length = 264
Score = 254 bits (648), Expect = 3e-67
Identities = 131/187 (70%), Positives = 151/187 (80%), Gaps = 3/187 (1%)
Query: 18 HQPAQPFKFTISESCDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGL 77
H P Q KFT S+SCDRIK+EFQ LQAQYHSLKLEC+KLASEK+EMQRHYVMYYEMSYGL
Sbjct: 80 HLPQQ-LKFTTSDSCDRIKDEFQLLQAQYHSLKLECDKLASEKSEMQRHYVMYYEMSYGL 138
Query: 78 NIEMHKQAEIVKRLNAICAQVIPFLSQEHQQQVVQAVERAKQVTMAELNAIIGQQLQAQH 137
NIEMHKQAEIVKRLN ICAQV+P+LSQEHQQQV+ A+ERAKQVT ELN+II QQLQA
Sbjct: 139 NIEMHKQAEIVKRLNGICAQVLPYLSQEHQQQVLGAIERAKQVTAPELNSIIRQQLQAHQ 198
Query: 138 LSHGHGLPVPLTPHPSGLQPPAIPPIGSSAGLLALSSALGGQSHLPIKDEKKHHDNDHQR 197
LS L +PLTP P GLQPP++P + + GLL+L SALG Q+HL K++K HD D +
Sbjct: 199 LSQLQALALPLTPLPVGLQPPSLPAVSAGTGLLSL-SALGSQAHLS-KEDKNGHDGDTHQ 256
Query: 198 DRDSIKS 204
+ D KS
Sbjct: 257 EDDGEKS 263
>gi|221136834 transducin-like enhancer of split 6 isoform 1 [Homo
sapiens]
Length = 572
Score = 203 bits (517), Expect = 4e-52
Identities = 108/315 (34%), Positives = 180/315 (57%), Gaps = 10/315 (3%)
Query: 466 PDALIGPG----IPRHARQINTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDISHP--G 519
PDAL G +P ++ L HGE+V A IS+ TRHV+T G+ +KVW ++
Sbjct: 261 PDALPGQSKRLAVPCKLEKMRILAHGELVLATAISSFTRHVFTCGRRGIKVWSLTGQVAE 320
Query: 520 NKSPVSQLDCLNRDNYIRSCRLLPDGRTLIVGG-EASTLSIWDLAAPTPRIKAELTSSAP 578
++ P S L ++R+C L + R+L+ GG +++S+WDLAAP+ +K +L +
Sbjct: 321 DRFPESHLPIQTPGAFLRTCLLSSNSRSLLTGGYNLASVSVWDLAAPSLHVKEQLPCAGL 380
Query: 579 ACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGG 638
C AL + D+ + F+ + G + +WDL +Q++VR +G+ DG I + G +WTGG
Sbjct: 381 NCQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKSIVVK--GYNIWTGG 438
Query: 639 LDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMENSNVEVLHVTKPDKYQLH 698
D +R WD R + ++ F SQI SL + P +W+ +GM N + + ++ +
Sbjct: 439 PDACLRCWDQRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMANGQQWLQSTSGSQRHMVG 498
Query: 699 LHESCVLSLKFAHCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIV 758
+S +LS+KF+ G+W+ S G D+ L + P G +F+ E S V CD+S +++ +V
Sbjct: 499 QKDSVILSVKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEVPEMSPVTCCDVSSNNRLVV 558
Query: 759 TGSGDKKATVYEVIY 773
TGSG+ A+VY++ Y
Sbjct: 559 TGSGE-HASVYQITY 572
>gi|13376099 transducin-like enhancer of split 6 isoform 2 [Homo
sapiens]
Length = 449
Score = 203 bits (517), Expect = 4e-52
Identities = 108/315 (34%), Positives = 180/315 (57%), Gaps = 10/315 (3%)
Query: 466 PDALIGPG----IPRHARQINTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDISHP--G 519
PDAL G +P ++ L HGE+V A IS+ TRHV+T G+ +KVW ++
Sbjct: 138 PDALPGQSKRLAVPCKLEKMRILAHGELVLATAISSFTRHVFTCGRRGIKVWSLTGQVAE 197
Query: 520 NKSPVSQLDCLNRDNYIRSCRLLPDGRTLIVGG-EASTLSIWDLAAPTPRIKAELTSSAP 578
++ P S L ++R+C L + R+L+ GG +++S+WDLAAP+ +K +L +
Sbjct: 198 DRFPESHLPIQTPGAFLRTCLLSSNSRSLLTGGYNLASVSVWDLAAPSLHVKEQLPCAGL 257
Query: 579 ACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGG 638
C AL + D+ + F+ + G + +WDL +Q++VR +G+ DG I + G +WTGG
Sbjct: 258 NCQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKSIVVK--GYNIWTGG 315
Query: 639 LDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMENSNVEVLHVTKPDKYQLH 698
D +R WD R + ++ F SQI SL + P +W+ +GM N + + ++ +
Sbjct: 316 PDACLRCWDQRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMANGQQWLQSTSGSQRHMVG 375
Query: 699 LHESCVLSLKFAHCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIV 758
+S +LS+KF+ G+W+ S G D+ L + P G +F+ E S V CD+S +++ +V
Sbjct: 376 QKDSVILSVKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEVPEMSPVTCCDVSSNNRLVV 435
Query: 759 TGSGDKKATVYEVIY 773
TGSG+ A+VY++ Y
Sbjct: 436 TGSGE-HASVYQITY 449
>gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens]
Length = 369
Score = 92.0 bits (227), Expect = 2e-18
Identities = 60/259 (23%), Positives = 115/259 (44%), Gaps = 12/259 (4%)
Query: 478 ARQINTLNHGEVVCAVTISNPTRHVYTGGKG--CVKVWDISHPGNKSPVSQLDCLNRDNY 535
+R H + V V S P+ H+ G V++W + + +S V +
Sbjct: 14 SRAYRFTGHKDAVTCVNFS-PSGHLLASGSRDKTVRIW-VPNVKGESTVFRAHTAT---- 67
Query: 536 IRSCRLLPDGRTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSC 595
+RS DG++ + + T+ +W A + L+ SPD ++ S
Sbjct: 68 VRSVHFCSDGQSFVTASDDKTVKVW--ATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSA 125
Query: 596 CSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQ 655
D + +WD ++ V + H + +D GT + G+DNTV+ WD+R R LQ
Sbjct: 126 SDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQ 185
Query: 656 QHDF-TSQIFSLGYCPTGEWLAVGMENSNVEVLHVTKPD-KYQLHLHESCVLSLKFAHCG 713
+ ++ + L + P+G +L +S +++L + + Y LH H+ ++ F+ G
Sbjct: 186 HYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTG 245
Query: 714 KWFVSTGKDNLLNAWRTPY 732
++F S G D + W++ +
Sbjct: 246 EYFASGGSDEQVMVWKSNF 264
Score = 56.6 bits (135), Expect = 8e-08
Identities = 35/133 (26%), Positives = 58/133 (43%), Gaps = 2/133 (1%)
Query: 598 DGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLR-EGRQLQQ 656
D + VW + Q+ +F GH D +C++ S G L +G D TVR W +G
Sbjct: 2 DSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVF 61
Query: 657 HDFTSQIFSLGYCPTGEWLAVGMENSNVEVLHVTKPD-KYQLHLHESCVLSLKFAHCGKW 715
T+ + S+ +C G+ ++ V+V + + L H + V KF+ G+
Sbjct: 62 RAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRL 121
Query: 716 FVSTGKDNLLNAW 728
VS D + W
Sbjct: 122 IVSASDDKTVKLW 134
>gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens]
Length = 359
Score = 92.0 bits (227), Expect = 2e-18
Identities = 60/259 (23%), Positives = 115/259 (44%), Gaps = 12/259 (4%)
Query: 478 ARQINTLNHGEVVCAVTISNPTRHVYTGGKG--CVKVWDISHPGNKSPVSQLDCLNRDNY 535
+R H + V V S P+ H+ G V++W + + +S V +
Sbjct: 52 SRAYRFTGHKDAVTCVNFS-PSGHLLASGSRDKTVRIW-VPNVKGESTVFRAHTAT---- 105
Query: 536 IRSCRLLPDGRTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSC 595
+RS DG++ + + T+ +W A + L+ SPD ++ S
Sbjct: 106 VRSVHFCSDGQSFVTASDDKTVKVW--ATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSA 163
Query: 596 CSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQ 655
D + +WD ++ V + H + +D GT + G+DNTV+ WD+R R LQ
Sbjct: 164 SDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQ 223
Query: 656 QHDF-TSQIFSLGYCPTGEWLAVGMENSNVEVLHVTKPD-KYQLHLHESCVLSLKFAHCG 713
+ ++ + L + P+G +L +S +++L + + Y LH H+ ++ F+ G
Sbjct: 224 HYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTG 283
Query: 714 KWFVSTGKDNLLNAWRTPY 732
++F S G D + W++ +
Sbjct: 284 EYFASGGSDEQVMVWKSNF 302
Score = 65.9 bits (159), Expect = 1e-10
Identities = 42/166 (25%), Positives = 78/166 (46%), Gaps = 7/166 (4%)
Query: 610 TLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQ---IFSL 666
+L R F+GH D +C+D S + +L +G +D+ + W ++ Q + + FT + +
Sbjct: 10 SLERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKP--QSRAYRFTGHKDAVTCV 67
Query: 667 GYCPTGEWLAVGMENSNVEV-LHVTKPDKYQLHLHESCVLSLKFAHCGKWFVSTGKDNLL 725
+ P+G LA G + V + + K + H + V S+ F G+ FV+ D +
Sbjct: 68 NFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTV 127
Query: 726 NAWRTPYGASIFQSKESSSVLSC-DISVDDKYIVTGSGDKKATVYE 770
W T +F + + + C S D + IV+ S DK +++
Sbjct: 128 KVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWD 173
Score = 59.7 bits (143), Expect = 1e-08
Identities = 41/167 (24%), Positives = 69/167 (41%), Gaps = 2/167 (1%)
Query: 564 APTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGAS 623
A P ++ A + S ++K S D + VW + Q+ +F GH D +
Sbjct: 6 AEDPSLERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVT 65
Query: 624 CIDISNDGTKLWTGGLDNTVRSWDLR-EGRQLQQHDFTSQIFSLGYCPTGEWLAVGMENS 682
C++ S G L +G D TVR W +G T+ + S+ +C G+ ++
Sbjct: 66 CVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDK 125
Query: 683 NVEVLHVTKPD-KYQLHLHESCVLSLKFAHCGKWFVSTGKDNLLNAW 728
V+V + + L H + V KF+ G+ VS D + W
Sbjct: 126 TVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLW 172
>gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens]
Length = 407
Score = 92.0 bits (227), Expect = 2e-18
Identities = 60/259 (23%), Positives = 115/259 (44%), Gaps = 12/259 (4%)
Query: 478 ARQINTLNHGEVVCAVTISNPTRHVYTGGKG--CVKVWDISHPGNKSPVSQLDCLNRDNY 535
+R H + V V S P+ H+ G V++W + + +S V +
Sbjct: 52 SRAYRFTGHKDAVTCVNFS-PSGHLLASGSRDKTVRIW-VPNVKGESTVFRAHTAT---- 105
Query: 536 IRSCRLLPDGRTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSC 595
+RS DG++ + + T+ +W A + L+ SPD ++ S
Sbjct: 106 VRSVHFCSDGQSFVTASDDKTVKVW--ATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSA 163
Query: 596 CSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQ 655
D + +WD ++ V + H + +D GT + G+DNTV+ WD+R R LQ
Sbjct: 164 SDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQ 223
Query: 656 QHDF-TSQIFSLGYCPTGEWLAVGMENSNVEVLHVTKPD-KYQLHLHESCVLSLKFAHCG 713
+ ++ + L + P+G +L +S +++L + + Y LH H+ ++ F+ G
Sbjct: 224 HYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTG 283
Query: 714 KWFVSTGKDNLLNAWRTPY 732
++F S G D + W++ +
Sbjct: 284 EYFASGGSDEQVMVWKSNF 302
Score = 65.9 bits (159), Expect = 1e-10
Identities = 42/166 (25%), Positives = 78/166 (46%), Gaps = 7/166 (4%)
Query: 610 TLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQ---IFSL 666
+L R F+GH D +C+D S + +L +G +D+ + W ++ Q + + FT + +
Sbjct: 10 SLERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKP--QSRAYRFTGHKDAVTCV 67
Query: 667 GYCPTGEWLAVGMENSNVEV-LHVTKPDKYQLHLHESCVLSLKFAHCGKWFVSTGKDNLL 725
+ P+G LA G + V + + K + H + V S+ F G+ FV+ D +
Sbjct: 68 NFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTV 127
Query: 726 NAWRTPYGASIFQSKESSSVLSC-DISVDDKYIVTGSGDKKATVYE 770
W T +F + + + C S D + IV+ S DK +++
Sbjct: 128 KVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWD 173
Score = 59.7 bits (143), Expect = 1e-08
Identities = 41/167 (24%), Positives = 69/167 (41%), Gaps = 2/167 (1%)
Query: 564 APTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGAS 623
A P ++ A + S ++K S D + VW + Q+ +F GH D +
Sbjct: 6 AEDPSLERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVT 65
Query: 624 CIDISNDGTKLWTGGLDNTVRSWDLR-EGRQLQQHDFTSQIFSLGYCPTGEWLAVGMENS 682
C++ S G L +G D TVR W +G T+ + S+ +C G+ ++
Sbjct: 66 CVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDK 125
Query: 683 NVEVLHVTKPD-KYQLHLHESCVLSLKFAHCGKWFVSTGKDNLLNAW 728
V+V + + L H + V KF+ G+ VS D + W
Sbjct: 126 TVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLW 172
>gi|26665869 WD repeat domain 51B [Homo sapiens]
Length = 478
Score = 88.2 bits (217), Expect = 3e-17
Identities = 64/259 (24%), Positives = 110/259 (42%), Gaps = 10/259 (3%)
Query: 477 HARQINTLNHGEVVCAVTISNPTRHVYTGGKG-CVKVWDISHPGNKSPVSQLDCLNRDNY 535
HAR + H +VV +V S + + + V++W P + S+
Sbjct: 50 HARAYRYVGHKDVVTSVQFSPHGNLLASASRDRTVRLWI---PDKRGKFSEFKAHTAP-- 104
Query: 536 IRSCRLLPDGRTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSC 595
+RS DG+ L E ++ +W + R L SPD ++ SC
Sbjct: 105 VRSVDFSADGQFLATASEDKSIKVWSMYRQ--RFLYSLYRHTHWVRCAKFSPDGRLIVSC 162
Query: 596 CSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQ 655
D I +WD N+ V F A+ +D + GT + + G D TV+ WD+R + LQ
Sbjct: 163 SEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQ 222
Query: 656 QHDFTS-QIFSLGYCPTGEWLAVGMENSNVEVLHVTKPDK-YQLHLHESCVLSLKFAHCG 713
+ S + + + P+G +L + +++L + + Y L H V ++ F+ G
Sbjct: 223 HYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGG 282
Query: 714 KWFVSTGKDNLLNAWRTPY 732
+ F S G D + WRT +
Sbjct: 283 ELFASGGADTQVLLWRTNF 301
Score = 60.1 bits (144), Expect = 8e-09
Identities = 46/212 (21%), Positives = 88/212 (41%), Gaps = 3/212 (1%)
Query: 563 AAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGA 622
A P ++ A +L +SP+ K + D + +W+ ++ GH D
Sbjct: 4 ATEDPVLERYFKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVV 63
Query: 623 SCIDISNDGTKLWTGGLDNTVRSW-DLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMEN 681
+ + S G L + D TVR W + G+ + T+ + S+ + G++LA E+
Sbjct: 64 TSVQFSPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASED 123
Query: 682 SNVEVLHVTKPD-KYQLHLHESCVLSLKFAHCGKWFVSTGKDNLLNAWRTPYGASIFQSK 740
+++V + + Y L+ H V KF+ G+ VS +D + W T +
Sbjct: 124 KSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFS 183
Query: 741 ESSSVLS-CDISVDDKYIVTGSGDKKATVYEV 771
+S + D + I + D+ V++V
Sbjct: 184 DSVGFANFVDFNPSGTCIASAGSDQTVKVWDV 215
>gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens]
Length = 357
Score = 83.2 bits (204), Expect = 8e-16
Identities = 61/243 (25%), Positives = 104/243 (42%), Gaps = 12/243 (4%)
Query: 539 CRLLPDGRTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSD 598
C+ P+G TL G + +W++ A L + A L + D + FS +D
Sbjct: 72 CKFHPNGSTLASAGFDRLILLWNVYGDCDNY-ATLKGHSGAVMELHYNTDGSMLFSASTD 130
Query: 599 GNIAVWDLHNQTLVRQFQGHTDGA-SCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQH 657
+AVWD V++ +GHT SC + TG D TV+ WD+R+ +Q
Sbjct: 131 KTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTF 190
Query: 658 DFTSQIFSLGYCPTGEWLAVGMENSNVEVLHVTKPD-KYQLHLHESCVLSLKFAHCGKWF 716
T Q+ ++ + T + + G +++++V + + Y + H V L + G +
Sbjct: 191 QNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYL 250
Query: 717 VSTGKDNLLNAWRT-PYG-----ASIFQSKE---SSSVLSCDISVDDKYIVTGSGDKKAT 767
+S DN + W P+ IFQ ++L C S D I GS D+
Sbjct: 251 LSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVY 310
Query: 768 VYE 770
V++
Sbjct: 311 VWD 313
Score = 68.2 bits (165), Expect = 3e-11
Identities = 60/229 (26%), Positives = 97/229 (42%), Gaps = 23/229 (10%)
Query: 510 VKVWDISHPGNKSPVSQLDCLNRDNYIRSCRLLPDGRTLI-VGGEASTLSIWDLAAPTPR 568
V VWD S G + V +L +++ SC G L+ G + T+ +WD+ R
Sbjct: 133 VAVWD-SETGER--VKRLK--GHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDI-----R 182
Query: 569 IKAELTSSAPACYALAIS--PDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCID 626
KA + + LA++ S S D +I VWDL L +GH D + +
Sbjct: 183 KKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLS 242
Query: 627 ISNDGTKLWTGGLDNTVRSWDLREGRQLQQ---------HDFTSQIFSLGYCPTGEWLAV 677
+S++G+ L + +DNTVR WD+R ++ H+F + + P G +A
Sbjct: 243 LSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAA 302
Query: 678 GMENSNVEVLHVT-KPDKYQLHLHESCVLSLKFAHCGKWFVSTGKDNLL 725
G + V V T + Y+L H + + F +S D L
Sbjct: 303 GSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRL 351
Score = 32.7 bits (73), Expect = 1.3
Identities = 38/169 (22%), Positives = 62/169 (36%), Gaps = 8/169 (4%)
Query: 609 QTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSW----DLREGRQLQQHDFTSQIF 664
Q + GH C +G+ L + G D + W D L+ H + +
Sbjct: 56 QAPIMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGH--SGAVM 113
Query: 665 SLGYCPTGEWLAVGMENSNVEVLHVTKPDKY-QLHLHESCVLSLKFAHCGKWFVSTGKDN 723
L Y G L + V V ++ +L H S V S A G V TG D+
Sbjct: 114 ELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDD 173
Query: 724 -LLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIVTGSGDKKATVYEV 771
+ W A+I + + VL+ + I++G D V+++
Sbjct: 174 GTVKLWDIRKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDL 222
>gi|5729852 guanine nucleotide-binding protein, beta-5 subunit
isoform a [Homo sapiens]
Length = 353
Score = 82.4 bits (202), Expect = 1e-15
Identities = 72/299 (24%), Positives = 125/299 (41%), Gaps = 23/299 (7%)
Query: 486 HG-EVVCAVTISNPTRHVYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIRSCRLLPD 544
HG +V+C + R V + G V VWD S NK + C ++ +C P
Sbjct: 62 HGNKVLCMDWCKDKRRIVSSSQDGKVIVWD-SFTTNKEHAVTMPC----TWVMACAYAPS 116
Query: 545 GRTLIVGGEASTLSIWDLA-------APTPRIKAELTSSAPACYALAISPDSKVCFSCCS 597
G + GG + S++ L A + A T+ AC + + +
Sbjct: 117 GCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSAC---SFTNSDMQILTASG 173
Query: 598 DGNIAVWDLHNQTLVRQFQGHTDGASCIDI--SNDGTKLWTGGLDNTVRSWDLREGRQLQ 655
DG A+WD+ + L++ F GH C+D+ S G +GG D WD+R G+ +Q
Sbjct: 174 DGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQ 233
Query: 656 QHD-FTSQIFSLGYCPTGEWLAVGMENSNVEVLHVTKPDKYQLHLHESCVL---SLKFAH 711
+ S I S+ Y P+G+ A G +++ + + + ++ ES + S+ F+
Sbjct: 234 AFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSL 293
Query: 712 CGKWFVSTGKDNLLNAWRTPYGASI-FQSKESSSVLSCDISVDDKYIVTGSGDKKATVY 769
G+ + D +N W G+ + + V + +S D +GS D V+
Sbjct: 294 SGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 352
Score = 35.8 bits (81), Expect = 0.16
Identities = 37/173 (21%), Positives = 70/173 (40%), Gaps = 17/173 (9%)
Query: 613 RQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFT---SQIFSLGYC 669
R +GH + C+D D ++ + D V WD ++H T + + + Y
Sbjct: 57 RTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWD--SFTTNKEHAVTMPCTWVMACAYA 114
Query: 670 PTGEWLAVGMENSNVEVLHVT-------KPDKYQLHLHESCVLSLKFAHCGKWFVSTGKD 722
P+G +A G ++ V +T K + +H + + + F + ++ D
Sbjct: 115 PSGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGD 174
Query: 723 NLLNAWRTPYGASIFQS--KESSSVLSCDISVDD--KYIVTGSGDKKATVYEV 771
W G + QS + VL D++ + V+G DKKA V+++
Sbjct: 175 GTCALWDVESG-QLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDM 226
>gi|20336270 guanine nucleotide-binding protein, beta-5 subunit
isoform b [Homo sapiens]
Length = 395
Score = 82.4 bits (202), Expect = 1e-15
Identities = 72/299 (24%), Positives = 125/299 (41%), Gaps = 23/299 (7%)
Query: 486 HG-EVVCAVTISNPTRHVYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIRSCRLLPD 544
HG +V+C + R V + G V VWD S NK + C ++ +C P
Sbjct: 104 HGNKVLCMDWCKDKRRIVSSSQDGKVIVWD-SFTTNKEHAVTMPC----TWVMACAYAPS 158
Query: 545 GRTLIVGGEASTLSIWDLA-------APTPRIKAELTSSAPACYALAISPDSKVCFSCCS 597
G + GG + S++ L A + A T+ AC + + +
Sbjct: 159 GCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSAC---SFTNSDMQILTASG 215
Query: 598 DGNIAVWDLHNQTLVRQFQGHTDGASCIDI--SNDGTKLWTGGLDNTVRSWDLREGRQLQ 655
DG A+WD+ + L++ F GH C+D+ S G +GG D WD+R G+ +Q
Sbjct: 216 DGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQ 275
Query: 656 QHD-FTSQIFSLGYCPTGEWLAVGMENSNVEVLHVTKPDKYQLHLHESCVL---SLKFAH 711
+ S I S+ Y P+G+ A G +++ + + + ++ ES + S+ F+
Sbjct: 276 AFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSL 335
Query: 712 CGKWFVSTGKDNLLNAWRTPYGASI-FQSKESSSVLSCDISVDDKYIVTGSGDKKATVY 769
G+ + D +N W G+ + + V + +S D +GS D V+
Sbjct: 336 SGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
Score = 35.8 bits (81), Expect = 0.16
Identities = 37/173 (21%), Positives = 70/173 (40%), Gaps = 17/173 (9%)
Query: 613 RQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFT---SQIFSLGYC 669
R +GH + C+D D ++ + D V WD ++H T + + + Y
Sbjct: 99 RTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWD--SFTTNKEHAVTMPCTWVMACAYA 156
Query: 670 PTGEWLAVGMENSNVEVLHVT-------KPDKYQLHLHESCVLSLKFAHCGKWFVSTGKD 722
P+G +A G ++ V +T K + +H + + + F + ++ D
Sbjct: 157 PSGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGD 216
Query: 723 NLLNAWRTPYGASIFQS--KESSSVLSCDISVDD--KYIVTGSGDKKATVYEV 771
W G + QS + VL D++ + V+G DKKA V+++
Sbjct: 217 GTCALWDVESG-QLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDM 268
>gi|24431950 PRP4 pre-mRNA processing factor 4 homolog [Homo
sapiens]
Length = 522
Score = 73.2 bits (178), Expect = 9e-13
Identities = 56/213 (26%), Positives = 93/213 (43%), Gaps = 6/213 (2%)
Query: 556 TLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQF 615
++ +W L + P A++ + P + + C D + +WDL Q +
Sbjct: 304 SVKLWSLDSDEP--VADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQ 361
Query: 616 QGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQ-QHDFTSQIFSLGYCPTGEW 674
+GH+ G I DG+ TGGLD R WDLR GR + +I+ + + P G
Sbjct: 362 EGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYH 421
Query: 675 LAVGMENSNVEVLHV-TKPDKYQLHLHESCVLSLKFAHCGKWFVSTGK-DNLLNAWRTPY 732
+A G ++ +V + + Y + H++ V +KF F+ TG DN W P
Sbjct: 422 IATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPG 481
Query: 733 GASI-FQSKESSSVLSCDISVDDKYIVTGSGDK 764
+ + + V+ DIS D + I T S D+
Sbjct: 482 WSPLKTLAGHEGKVMGLDISSDGQLIATCSYDR 514
Score = 41.6 bits (96), Expect = 0.003
Identities = 51/248 (20%), Positives = 78/248 (31%), Gaps = 51/248 (20%)
Query: 533 DNYIRSCRLLPDGRTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVC 592
D I C P+ + L + +W + P + L A+ P S V
Sbjct: 231 DRPISYCHFSPNSKMLATACWSGLCKLWSV--PDCNLLHTLRGHNTNVGAIVFHPKSTVS 288
Query: 593 F--------SCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVR 644
SC +DG++ +W L + V +GHT + + G L T D + R
Sbjct: 289 LDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWR 348
Query: 645 SWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMENSNVEVLHVTKPDKYQLHLHESCV 704
WDL + E+LH H V
Sbjct: 349 LWDLE--------------------------------AQEEILHQEG--------HSMGV 368
Query: 705 LSLKFAHCGKWFVSTGKDNLLNAWRTPYGASI-FQSKESSSVLSCDISVDDKYIVTGSGD 763
+ F G + G D W G I F + + S + +I TGSGD
Sbjct: 369 YDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGD 428
Query: 764 KKATVYEV 771
V+++
Sbjct: 429 NTCKVWDL 436
Score = 30.8 bits (68), Expect = 5.0
Identities = 22/105 (20%), Positives = 38/105 (36%), Gaps = 3/105 (2%)
Query: 543 PDGRTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISP-DSKVCFSCCSDGNI 601
P+G + G +T +WDL R + + + P + D
Sbjct: 417 PNGYHIATGSGDNTCKVWDLRQR--RCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTA 474
Query: 602 AVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSW 646
+W + ++ GH +DIS+DG + T D T + W
Sbjct: 475 KIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 519
>gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo
sapiens]
Length = 421
Score = 71.6 bits (174), Expect = 3e-12
Identities = 63/257 (24%), Positives = 98/257 (38%), Gaps = 35/257 (13%)
Query: 508 GCVKVWDISHPGNKSPVSQLDCLNRDNYIRSCRLLPDGRTLIVGGEAS-TLSIWDLAAPT 566
G +K+WD+ + G L+ ++ +R PDG ++V TL +WDL
Sbjct: 150 GRIKIWDV-YTGKLL----LNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDG 204
Query: 567 PRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCID 626
+K L Y+ A SPDS + S + + +W++ T++R+ +GH D
Sbjct: 205 NMMKV-LRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACD 263
Query: 627 ISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMENSNVEV 686
S DG L T D V WD G L + F + P A G
Sbjct: 264 FSPDGALLATASYDTRVYIWDPHNGDILME-------FGHLFPPPTPIFAGGA------- 309
Query: 687 LHVTKPDKYQLHLHESCVLSLKFAHCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVL 746
++ V S+ F+H G S D ++ WR + Q S+ L
Sbjct: 310 -------------NDRWVRSVSFSHDGLHVASLADDKMVRFWRIDEDYPV-QVAPLSNGL 355
Query: 747 SCDISVDDKYIVTGSGD 763
C S D + G+ D
Sbjct: 356 CCAFSTDGSVLAAGTHD 372
Score = 53.9 bits (128), Expect = 6e-07
Identities = 51/220 (23%), Positives = 88/220 (40%), Gaps = 24/220 (10%)
Query: 481 INTLNHGEVVCAVTISNPTRHVYTGGKG--CVKVWDISHPGNKSPVSQLDCLNRDNYIRS 538
+N ++H EVV +T + + ++VWD+ GN V + N++ S
Sbjct: 164 LNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLR----GHQNWVYS 219
Query: 539 CRLLPDGRTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSD 598
C PD L G + + +W++ T K E A SPD + + D
Sbjct: 220 CAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLE--GHHHDVVACDFSPDGALLATASYD 277
Query: 599 GNIAVWDLHNQTLVRQFQGH---------TDGAS-----CIDISNDGTKLWTGGLDNTVR 644
+ +WD HN ++ +F GH GA+ + S+DG + + D VR
Sbjct: 278 TRVYIWDPHNGDILMEF-GHLFPPPTPIFAGGANDRWVRSVSFSHDGLHVASLADDKMVR 336
Query: 645 SWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMENSNV 684
W + E +Q ++ + + G LA G + +V
Sbjct: 337 FWRIDEDYPVQVAPLSNGL-CCAFSTDGSVLAAGTHDGSV 375
Score = 39.7 bits (91), Expect = 0.011
Identities = 31/140 (22%), Positives = 61/140 (43%), Gaps = 12/140 (8%)
Query: 597 SDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTK-LWTGGLDNTVRSWDLREGRQLQ 655
++G I +WD++ L+ HT+ + + DG+ L + D T+R WDL++ +
Sbjct: 148 NNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMM 207
Query: 656 Q--HDFTSQIFSLGYCPTGEWL-AVGMENSNVEVLHVTKPDKY----QLHLHESCVLSLK 708
+ + ++S + P L +VG + + + DKY +L H V++
Sbjct: 208 KVLRGHQNWVYSCAFSPDSSMLCSVGAS----KAVFLWNMDKYTMIRKLEGHHHDVVACD 263
Query: 709 FAHCGKWFVSTGKDNLLNAW 728
F+ G + D + W
Sbjct: 264 FSPDGALLATASYDTRVYIW 283
>gi|5174447 guanine nucleotide binding protein (G protein), beta
polypeptide 2-like 1 [Homo sapiens]
Length = 317
Score = 71.2 bits (173), Expect = 3e-12
Identities = 52/205 (25%), Positives = 88/205 (42%), Gaps = 11/205 (5%)
Query: 473 GIPRHARQINTLNHGEVVCAVTISNPTRHVYTGG-KGCVKVWDISHPGNKSPVSQLDCLN 531
GIP+ A + H V V IS+ + +G G +++WD++ + + +
Sbjct: 53 GIPQRALR----GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLT-----TGTTTRRFVG 103
Query: 532 RDNYIRSCRLLPDGRTLIVGGEASTLSIWD-LAAPTPRIKAELTSSAPACYALAISPDSK 590
+ S D R ++ G T+ +W+ L ++ E S +C + + +
Sbjct: 104 HTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNP 163
Query: 591 VCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLRE 650
+ SC D + VW+L N L GHT + + +S DG+ +GG D WDL E
Sbjct: 164 IIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNE 223
Query: 651 GRQLQQHDFTSQIFSLGYCPTGEWL 675
G+ L D I +L + P WL
Sbjct: 224 GKHLYTLDGGDIINALCFSPNRYWL 248
Score = 45.4 bits (106), Expect = 2e-04
Identities = 45/180 (25%), Positives = 73/180 (40%), Gaps = 23/180 (12%)
Query: 485 NHGEVVCAVTISNPTRH---VYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIRSCRL 541
+H E V V S + + V G VKVW++++ K+ + + Y+ + +
Sbjct: 146 SHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKT-----NHIGHTGYLNTVTV 200
Query: 542 LPDGRTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDG-N 600
PDG GG+ +WDL + AL SP+ + C + G +
Sbjct: 201 SPDGSLCASGGKDGQAMLWDLNEGKHLYTLD---GGDIINALCFSPNRY--WLCAATGPS 255
Query: 601 IAVWDLHNQTLVRQFQGHTDGAS-------CIDI--SNDGTKLWTGGLDNTVRSWDLREG 651
I +WDL + +V + + S C + S DG L+ G DN VR W + G
Sbjct: 256 IKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIG 315
>gi|11055998 guanine nucleotide-binding protein, beta-4 subunit
[Homo sapiens]
Length = 340
Score = 70.9 bits (172), Expect = 4e-12
Identities = 61/263 (23%), Positives = 108/263 (41%), Gaps = 13/263 (4%)
Query: 508 GCVKVWDISHPGNKSPVSQLDCLNRDNYIRSCRLLPDGRTLIVGGEASTLSIWDLAA--P 565
G + +WD S+ NK L R +++ +C P G + GG + SI++L
Sbjct: 77 GKLIIWD-SYTTNKMHAIPL----RSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREG 131
Query: 566 TPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCI 625
R+ EL DS++ S D A+WD+ F GH+ +
Sbjct: 132 NVRVSRELPGHTGYLSCCRFLDDSQIVTS-SGDTTCALWDIETAQQTTTFTGHSGDVMSL 190
Query: 626 DISNDGTKLWTGGLDNTVRSWDLREGRQLQQH-DFTSQIFSLGYCPTGEWLAVGMENSNV 684
+S D +G D + + WD+R+G Q S I ++ + P G A G +++
Sbjct: 191 SLSPDMRTFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYAFATGSDDATC 250
Query: 685 EVLHVTKPDKYQLHLHESC---VLSLKFAHCGKWFVSTGKDNLLNAWRTPYGASIFQSKE 741
+ + + L+ H++ + S+ F+ G+ ++ D N W T G
Sbjct: 251 RLFDLRADQELLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTLKGDRAGVLAG 310
Query: 742 SSSVLSC-DISVDDKYIVTGSGD 763
+ +SC ++ D + TGS D
Sbjct: 311 HDNRVSCLGVTDDGMAVATGSWD 333
Score = 67.4 bits (163), Expect = 5e-11
Identities = 51/198 (25%), Positives = 86/198 (43%), Gaps = 7/198 (3%)
Query: 535 YIRSCRLLPDGRTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFS 594
Y+ CR L D + + G+ +T ++WD+ T + T + +L++SPD + S
Sbjct: 145 YLSCCRFLDDSQIVTSSGD-TTCALWDIE--TAQQTTTFTGHSGDVMSLSLSPDMRTFVS 201
Query: 595 CCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQ- 653
D + +WD+ + + F GH + + +G TG D T R +DLR ++
Sbjct: 202 GACDASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYAFATGSDDATCRLFDLRADQEL 261
Query: 654 -LQQHD-FTSQIFSLGYCPTGEWLAVGMENSNVEVLHVTKPDKY-QLHLHESCVLSLKFA 710
L HD I S+ + +G L G ++ N V K D+ L H++ V L
Sbjct: 262 LLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTLKGDRAGVLAGHDNRVSCLGVT 321
Query: 711 HCGKWFVSTGKDNLLNAW 728
G + D+ L W
Sbjct: 322 DDGMAVATGSWDSFLRIW 339
Score = 49.7 bits (117), Expect = 1e-05
Identities = 38/172 (22%), Positives = 71/172 (41%), Gaps = 7/172 (4%)
Query: 478 ARQINTLN-HGEVVCAVTISNPTRHVYTGG-KGCVKVWDISHPGNKSPVSQLDCLNRDNY 535
A+Q T H V ++++S R +G K+WDI + + + +
Sbjct: 174 AQQTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKLWDI-----RDGMCRQSFTGHVSD 228
Query: 536 IRSCRLLPDGRTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSC 595
I + P+G G + +T ++DL A + + ++A S ++ +
Sbjct: 229 INAVSFFPNGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGRLLLAG 288
Query: 596 CSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWD 647
D N VWD GH + SC+ +++DG + TG D+ +R W+
Sbjct: 289 YDDFNCNVWDTLKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN 340
Score = 34.3 bits (77), Expect = 0.45
Identities = 34/149 (22%), Positives = 69/149 (46%), Gaps = 9/149 (6%)
Query: 629 NDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMENSNVEVLH 688
ND T + ++V +R R L+ H ++I+++ + L ++ + +
Sbjct: 26 NDATLVQITSNMDSVGRIQMRTRRTLRGH--LAKIYAMHWGYDSRLLVSASQDGKLIIWD 83
Query: 689 VTKPDK-YQLHLHESCVLSLKFAHCGKWFVSTGKDNLLNAW--RTPYGASIFQSKE---S 742
+K + + L S V++ +A G + G DN+ + + +T G ++ S+E
Sbjct: 84 SYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREG-NVRVSRELPGH 142
Query: 743 SSVLSCDISVDDKYIVTGSGDKKATVYEV 771
+ LSC +DD IVT SGD ++++
Sbjct: 143 TGYLSCCRFLDDSQIVTSSGDTTCALWDI 171
Score = 32.3 bits (72), Expect = 1.7
Identities = 21/86 (24%), Positives = 34/86 (39%), Gaps = 2/86 (2%)
Query: 568 RIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDI 627
R + L YA+ DS++ S DG + +WD + + +
Sbjct: 46 RTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAY 105
Query: 628 SNDGTKLWTGGLDNTVRSWDL--REG 651
+ G + GGLDN ++L REG
Sbjct: 106 APSGNYVACGGLDNICSIYNLKTREG 131
>gi|4504053 guanine nucleotide-binding protein, beta-3 subunit [Homo
sapiens]
Length = 340
Score = 70.1 bits (170), Expect = 7e-12
Identities = 62/262 (23%), Positives = 107/262 (40%), Gaps = 11/262 (4%)
Query: 508 GCVKVWDISHPGNKSPVSQLDCLNRDNYIRSCRLLPDGRTLIVGGEASTLSIWDLAAPTP 567
G + VWD S+ NK L R +++ +C P G + GG + SI++L +
Sbjct: 77 GKLIVWD-SYTTNKVHAIPL----RSSWVMTCAYAPSGNFVACGGLDNMCSIYNLKSREG 131
Query: 568 RIKAELTSSAPACY-ALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCID 626
+K SA Y + D + D A+WD+ F GHT +
Sbjct: 132 NVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLA 191
Query: 627 ISNDGTKLWTGGLDNTVRSWDLREGRQLQQH-DFTSQIFSLGYCPTGEWLAVGMENSNVE 685
+S D +G D + + WD+REG Q S I ++ + P GE + G ++++
Sbjct: 192 VSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCR 251
Query: 686 VLHVTKPDKYQLHLHESC---VLSLKFAHCGKWFVSTGKDNLLNAWRTPYGASIFQSKES 742
+ + + HES + S+ F+ G+ + D N W + +
Sbjct: 252 LFDLRADQELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGH 311
Query: 743 SSVLSC-DISVDDKYIVTGSGD 763
+ +SC ++ D + TGS D
Sbjct: 312 DNRVSCLGVTADGMAVATGSWD 333
Score = 68.2 bits (165), Expect = 3e-11
Identities = 51/198 (25%), Positives = 84/198 (42%), Gaps = 7/198 (3%)
Query: 535 YIRSCRLLPDGRTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFS 594
Y+ CR L D + G+ +T ++WD+ T + K C +LA+SPD + S
Sbjct: 145 YLSCCRFLDDNNIVTSSGD-TTCALWDIE--TGQQKTVFVGHTGDCMSLAVSPDFNLFIS 201
Query: 595 CCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQL 654
D + +WD+ T + F GH + I +G + TG D + R +DLR ++L
Sbjct: 202 GACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQEL 261
Query: 655 ---QQHDFTSQIFSLGYCPTGEWLAVGMENSNVEVLHVTKPDKYQ-LHLHESCVLSLKFA 710
I S+ + +G L G ++ N V K ++ L H++ V L
Sbjct: 262 ICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVT 321
Query: 711 HCGKWFVSTGKDNLLNAW 728
G + D+ L W
Sbjct: 322 ADGMAVATGSWDSFLKIW 339
Score = 51.2 bits (121), Expect = 4e-06
Identities = 34/159 (21%), Positives = 66/159 (41%), Gaps = 7/159 (4%)
Query: 491 CAVTISNPTRHVYTGGK--GCVKVWDISHPGNKSPVSQLDCLNRDNYIRSCRLLPDGRTL 548
C +P +++ G K+WD+ + + ++ I + P+G +
Sbjct: 187 CMSLAVSPDFNLFISGACDASAKLWDV-----REGTCRQTFTGHESDINAICFFPNGEAI 241
Query: 549 IVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHN 608
G + ++ ++DL A I S ++A S ++ F+ D N VWD
Sbjct: 242 CTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMK 301
Query: 609 QTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWD 647
V GH + SC+ ++ DG + TG D+ ++ W+
Sbjct: 302 SERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
Score = 38.1 bits (87), Expect = 0.031
Identities = 53/220 (24%), Positives = 80/220 (36%), Gaps = 33/220 (15%)
Query: 568 RIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDI 627
R + L YA+ + DSK+ S DG + VWD + V +
Sbjct: 46 RTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAY 105
Query: 628 SNDGTKLWTGGLDNTVRSWDL--REG-----RQLQQH----------DFTSQIFSLGYCP 670
+ G + GGLDN ++L REG R+L H D + + S G
Sbjct: 106 APSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTT 165
Query: 671 TGEWLAVGMENSNVEVLH-------VTKPDKYQLHLHESCVLSLKF-----AHCGKWFVS 718
W + V V H PD + L + +C S K C + F
Sbjct: 166 CALWDIETGQQKTVFVGHTGDCMSLAVSPD-FNLFISGACDASAKLWDVREGTCRQTF-- 222
Query: 719 TGKDNLLNA-WRTPYGASIFQSKESSSVLSCDISVDDKYI 757
TG ++ +NA P G +I + +S D+ D + I
Sbjct: 223 TGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELI 262
Score = 34.7 bits (78), Expect = 0.35
Identities = 30/129 (23%), Positives = 61/129 (47%), Gaps = 7/129 (5%)
Query: 648 LREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMENSNVEVLHVTKPDK-YQLHLHESCVLS 706
+R R L+ H ++I+++ + + L ++ + V +K + + L S V++
Sbjct: 45 MRTRRTLRGH--LAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMT 102
Query: 707 LKFAHCGKWFVSTGKDNLLNAWRTPYG-ASIFQSKESSS---VLSCDISVDDKYIVTGSG 762
+A G + G DN+ + + ++ S+E S+ LSC +DD IVT SG
Sbjct: 103 CAYAPSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSG 162
Query: 763 DKKATVYEV 771
D ++++
Sbjct: 163 DTTCALWDI 171
>gi|83779014 katanin p80 subunit B 1 [Homo sapiens]
Length = 655
Score = 70.1 bits (170), Expect = 7e-12
Identities = 48/194 (24%), Positives = 84/194 (43%), Gaps = 9/194 (4%)
Query: 500 RHVYTGGKGC-VKVWDISHPGNKSPVSQLDCLNRDNYIRSCRLLPDGRTLIVGGEASTLS 558
R + TGG C V +W I+ P + + + S RL ++ G ++ ++
Sbjct: 34 RLLATGGDDCRVNLWSINKPN-----CIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIR 88
Query: 559 IWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGH 618
+WDL A +I L +L P + S D NI +WD+ + V +++GH
Sbjct: 89 VWDLEAA--KILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGH 146
Query: 619 TDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQH-DFTSQIFSLGYCPTGEWLAV 677
+ C+ S DG L + D+TV+ WDL G+ + + T + + + P LA
Sbjct: 147 SQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLAS 206
Query: 678 GMENSNVEVLHVTK 691
G + + + K
Sbjct: 207 GSSDRTIRFWDLEK 220
Score = 60.5 bits (145), Expect = 6e-09
Identities = 34/147 (23%), Positives = 66/147 (44%), Gaps = 3/147 (2%)
Query: 545 GRTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVW 604
GR L GG+ +++W + P LT ++ ++ ++ + G+I VW
Sbjct: 33 GRLLATGGDDCRVNLWSI--NKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVW 90
Query: 605 DLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDL-REGRQLQQHDFTSQI 663
DL ++R GH +D G + +G D ++ WD+ R+G + + +
Sbjct: 91 DLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAV 150
Query: 664 FSLGYCPTGEWLAVGMENSNVEVLHVT 690
L + P G+WLA ++ V++ +T
Sbjct: 151 RCLRFSPDGKWLASAADDHTVKLWDLT 177
Score = 60.1 bits (144), Expect = 8e-09
Identities = 35/177 (19%), Positives = 78/177 (44%), Gaps = 3/177 (1%)
Query: 598 DGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQ- 656
D + +W ++ + GHT + ++ + G ++R WDL + L+
Sbjct: 42 DCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTL 101
Query: 657 HDFTSQIFSLGYCPTGEWLAVGMENSNVEVLHVTKPD-KYQLHLHESCVLSLKFAHCGKW 715
+ I SL + P GE++A G +++N+++ + + ++ H V L+F+ GKW
Sbjct: 102 MGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKW 161
Query: 716 FVSTGKDNLLNAWRTPYGASIFQ-SKESSSVLSCDISVDDKYIVTGSGDKKATVYEV 771
S D+ + W G + + + V + ++ + +GS D+ +++
Sbjct: 162 LASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDL 218
Score = 48.9 bits (115), Expect = 2e-05
Identities = 40/170 (23%), Positives = 68/170 (40%), Gaps = 17/170 (10%)
Query: 484 LNHGEVVCAVTISNPTRHVYTGGKGC-VKVWDISHPGNKSPVSQLDCLNR----DNYIRS 538
+ H +C++ V +G + +K+WDI G C+ R +R
Sbjct: 102 MGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKG---------CVFRYRGHSQAVRC 152
Query: 539 CRLLPDGRTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSD 598
R PDG+ L + T+ +WDL A ++ +E + P+ + S SD
Sbjct: 153 LRFSPDGKWLASAADDHTVKLWDLTAG--KMMSEFPGHTGPVNVVEFHPNEYLLASGSSD 210
Query: 599 GNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDN-TVRSWD 647
I WDL +V +G + + DG L++G D+ V W+
Sbjct: 211 RTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDSLRVYGWE 260
>gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens]
Length = 589
Score = 69.3 bits (168), Expect = 1e-11
Identities = 61/276 (22%), Positives = 103/276 (37%), Gaps = 37/276 (13%)
Query: 531 NRDNYIRSCRLLPDGRTLIVGGEASTLSIWDLAAPTPRIKAE------------------ 572
N + + + + PD + L G + S + +W L + ++K+E
Sbjct: 266 NTEQLLNTAEISPDSKLLAAGFDNSCIKLWSLR--SKKLKSEPHQVDVSRIHLACDILEE 323
Query: 573 --------------LTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGH 618
L Y+ DS SC D +I WDL + T +QGH
Sbjct: 324 EDDEDDNAGTEMKILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGH 383
Query: 619 TDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQH-DFTSQIFSLGYCPTGEWLAV 677
+DIS +G D T R W L+ + + + + + P +LA
Sbjct: 384 AYPVWDLDISPYSLYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLAT 443
Query: 678 GMENSNVEVLHVTKPDKYQLHL-HESCVLSLKFAHCGKWFVSTGKDNLLNAWRTPYGASI 736
G + V + + + +L H VLSL F+ GK+ S G+D L W G
Sbjct: 444 GSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLY 503
Query: 737 FQSK-ESSSVLSCDISVDDKYIVTGSGDKKATVYEV 771
+ + + ++ S S D I + S D V+++
Sbjct: 504 KELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDI 539
Score = 68.2 bits (165), Expect = 3e-11
Identities = 61/241 (25%), Positives = 96/241 (39%), Gaps = 20/241 (8%)
Query: 536 IRSCRLLPDGRTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSC 595
+ S R L D L+ E ++ WDL + T + + A + L ISP S S
Sbjct: 345 VYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQ--GHAYPVWDLDISPYSLYFASG 402
Query: 596 CSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQ 655
D +W +R + GH C+ + L TG D TVR W ++G ++
Sbjct: 403 SHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVR 462
Query: 656 QHDFTSQ---IFSLGYCPTGEWLAVGMENSNVEVLHVTKPDKY-QLHLHESCVLSLKFAH 711
FT + SL + P G++LA E+ +++ + Y +L H + SL F+
Sbjct: 463 L--FTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSP 520
Query: 712 CGKWFVSTGKDNLLNAW--RTPYGASIFQSKES----------SSVLSCDISVDDKYIVT 759
S DN + W R Y ++ S S+VLS + +VT
Sbjct: 521 DSGLIASASMDNSVRVWDIRNTYCSAPADGSSSELVGVYTGQMSNVLSVQFMACNLLLVT 580
Query: 760 G 760
G
Sbjct: 581 G 581
>gi|8923881 WD SOCS-box protein 2 [Homo sapiens]
Length = 404
Score = 68.9 bits (167), Expect = 2e-11
Identities = 59/257 (22%), Positives = 100/257 (38%), Gaps = 36/257 (14%)
Query: 508 GCVKVWDISHPGNKSPVSQLDCLNRDNYIRSCRLLPDGRTLIVGGEAS-TLSIWDLAAPT 566
G +K+W++ ++ + L+ + +R P G ++V TL IWDL
Sbjct: 133 GQIKIWEV-----QTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNKHG 187
Query: 567 PRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCID 626
+I+ L+ Y +ISPD + S + ++ +W + + TL+R+ +GH D
Sbjct: 188 KQIQV-LSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCD 246
Query: 627 ISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMENSNVEV 686
S D L T D V WD G +L+ T + M++S+V
Sbjct: 247 FSPDSALLVTASYDTNVIMWDPYTGERLRSLHHTQ-------------VDPAMDDSDV-- 291
Query: 687 LHVTKPDKYQLHLHESCVLSLKFAHCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVL 746
H S + S+ F+ G + + D LL W I + ++ L
Sbjct: 292 -------------HISSLRSVCFSPEGLYLATVADDRLLRIWALELKTPIAFAPMTNG-L 337
Query: 747 SCDISVDDKYIVTGSGD 763
C I TG+ D
Sbjct: 338 CCTFFPHGGVIATGTRD 354
Score = 39.3 bits (90), Expect = 0.014
Identities = 39/162 (24%), Positives = 67/162 (41%), Gaps = 8/162 (4%)
Query: 597 SDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTK-LWTGGLDNTVRSWDL-REGRQL 654
+DG I +W++ L+ GH D + + G+ L + D T+R WDL + G+Q+
Sbjct: 131 NDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNKHGKQI 190
Query: 655 QQHDFTSQ-IFSLGYCPTGEWLAVGMENSNVEVLHVTKPDKY-QLHLHESCVLSLKFAHC 712
Q Q ++ P L +V + + +L H+S V+S F+
Sbjct: 191 QVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCDFSPD 250
Query: 713 GKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISVDD 754
V+ D + W PY +S + V D ++DD
Sbjct: 251 SALLVTASYDTNVIMW-DPYTGERLRSLHHTQV---DPAMDD 288
>gi|21071067 TBP-associated factor 5 [Homo sapiens]
Length = 800
Score = 67.8 bits (164), Expect = 4e-11
Identities = 44/161 (27%), Positives = 76/161 (47%), Gaps = 8/161 (4%)
Query: 536 IRSCRLLPDGRTLIVGGEASTLSIWD-LAAPTPRIKAELTSSAPACYALAISPDSKVCFS 594
+ R P+ + G T+ +WD L RI T ++L SP+ + +
Sbjct: 630 VNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRI---FTGHKGPIHSLTFSPNGRFLAT 686
Query: 595 CCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWD-LREGRQ 653
+DG + +WD+ + +V + +GHTD + S DG L +G +DNTVR WD ++
Sbjct: 687 GATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAIKAFED 746
Query: 654 LQQHDFTSQIFSLGYCPTGEWLAVG---MENSNVEVLHVTK 691
L+ DFT+ + + L +G +++ V LH T+
Sbjct: 747 LETDDFTTATGHINLPENSQELLLGTYMTKSTPVVHLHFTR 787
Score = 54.7 bits (130), Expect = 3e-07
Identities = 52/233 (22%), Positives = 94/233 (40%), Gaps = 13/233 (5%)
Query: 553 EASTLSIWDLAAPT--PRIKAELTSS--------APACYALAISPDSKVCFSCCSDGNIA 602
+AS LS+ D + RI E T+S + Y + SPD S DG +
Sbjct: 509 QASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVR 568
Query: 603 VWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQH-DFTS 661
+W L T + ++GH S G +GG D R W + L+ +
Sbjct: 569 LWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLA 628
Query: 662 QIFSLGYCPTGEWLAVGMENSNVEVLHVTKPDKYQLHL-HESCVLSLKFAHCGKWFVSTG 720
+ + P ++A G + V + V + ++ H+ + SL F+ G++ +
Sbjct: 629 DVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGA 688
Query: 721 KDNLLNAWRTPYGASIFQSK-ESSSVLSCDISVDDKYIVTGSGDKKATVYEVI 772
D + W +G + + K + +V S S D + + +GS D +++ I
Sbjct: 689 TDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAI 741
>gi|20143912 WD repeat and SOCS box-containing 1 isoform 2 [Homo
sapiens]
Length = 275
Score = 67.8 bits (164), Expect = 4e-11
Identities = 58/238 (24%), Positives = 89/238 (37%), Gaps = 30/238 (12%)
Query: 527 LDCLNRDNYIRSCRLLPDGRTLIVGGEAS-TLSIWDLAAPTPRIKAELTSSAPACYALAI 585
L+ ++ +R PDG ++V TL +WDL +K L Y+ A
Sbjct: 18 LNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKV-LRGHQNWVYSCAF 76
Query: 586 SPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRS 645
SPDS + S + + +W++ T++R+ +GH D S DG L T D V
Sbjct: 77 SPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACDFSPDGALLATASYDTRVYI 136
Query: 646 WDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMENSNVEVLHVTKPDKYQLHLHESCVL 705
WD G L + F + P A G ++ V
Sbjct: 137 WDPHNGDILME-------FGHLFPPPTPIFAGG--------------------ANDRWVR 169
Query: 706 SLKFAHCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIVTGSGD 763
S+ F+H G S D ++ WR + Q S+ L C S D + G+ D
Sbjct: 170 SVSFSHDGLHVASLADDKMVRFWRIDEDYPV-QVAPLSNGLCCAFSTDGSVLAAGTHD 226
Score = 53.9 bits (128), Expect = 6e-07
Identities = 51/220 (23%), Positives = 88/220 (40%), Gaps = 24/220 (10%)
Query: 481 INTLNHGEVVCAVTISNPTRHVYTGGKG--CVKVWDISHPGNKSPVSQLDCLNRDNYIRS 538
+N ++H EVV +T + + ++VWD+ GN V + N++ S
Sbjct: 18 LNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLR----GHQNWVYS 73
Query: 539 CRLLPDGRTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSD 598
C PD L G + + +W++ T K E A SPD + + D
Sbjct: 74 CAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLE--GHHHDVVACDFSPDGALLATASYD 131
Query: 599 GNIAVWDLHNQTLVRQFQGH---------TDGAS-----CIDISNDGTKLWTGGLDNTVR 644
+ +WD HN ++ +F GH GA+ + S+DG + + D VR
Sbjct: 132 TRVYIWDPHNGDILMEF-GHLFPPPTPIFAGGANDRWVRSVSFSHDGLHVASLADDKMVR 190
Query: 645 SWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMENSNV 684
W + E +Q ++ + + G LA G + +V
Sbjct: 191 FWRIDEDYPVQVAPLSNGL-CCAFSTDGSVLAAGTHDGSV 229
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,156,415
Number of Sequences: 37866
Number of extensions: 1993100
Number of successful extensions: 16529
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 286
Number of HSP's successfully gapped in prelim test: 1087
Number of HSP's that attempted gapping in prelim test: 10150
Number of HSP's gapped (non-prelim): 5418
length of query: 773
length of database: 18,247,518
effective HSP length: 110
effective length of query: 663
effective length of database: 14,082,258
effective search space: 9336537054
effective search space used: 9336537054
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.