Guide to the Human Genome
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Search of human proteins with 34577120

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|34577120 mitochondrial translational release factor 1 [Homo
sapiens]
         (445 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|34577120 mitochondrial translational release factor 1 [Homo s...   904   0.0  
gi|166795303 mitochondrial translational release factor 1-like i...   323   3e-88
gi|166795305 mitochondrial translational release factor 1-like i...   210   2e-54
gi|219879802 hypothetical protein LOC91574 [Homo sapiens]              56   8e-08
gi|22748627 hypothetical protein LOC91574 [Homo sapiens]               56   8e-08
gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens]              44   4e-04
gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens]              43   7e-04
gi|116235478 establishment of cohesion 1 homolog 1 [Homo sapiens]      43   7e-04
gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens]                    42   0.001
gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens]                    41   0.002
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa...    40   0.003
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s...    40   0.003
gi|110815815 centlein isoform 1 [Homo sapiens]                         40   0.004
gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens]         39   0.007
gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens]         39   0.007
gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens]         39   0.007
gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens]         39   0.007
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr...    39   0.007
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr...    39   0.007
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo...    39   0.007
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ...    39   0.010
gi|114155146 tropomyosin 3 isoform 3 [Homo sapiens]                    39   0.012
gi|24119203 tropomyosin 3 isoform 2 [Homo sapiens]                     39   0.012
gi|50658069 phosphodiesterase 4D interacting protein isoform 2 [...    38   0.021
gi|157311604 phosphodiesterase 4D interacting protein isoform 1 ...    38   0.021
gi|50658077 phosphodiesterase 4D interacting protein isoform 4 [...    38   0.021
gi|50658075 phosphodiesterase 4D interacting protein isoform 3 [...    37   0.036
gi|56961680 coiled-coil domain containing 147 [Homo sapiens]           37   0.036
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...    36   0.062
gi|221139761 zinc finger protein 853 [Homo sapiens]                    36   0.081

>gi|34577120 mitochondrial translational release factor 1 [Homo
           sapiens]
          Length = 445

 Score =  904 bits (2335), Expect = 0.0
 Identities = 445/445 (100%), Positives = 445/445 (100%)

Query: 1   MNRHLCVWLFRHPSLNGYLQCHIQLHSHQFRQIHLDTRLQVFRQNRNCILHLLSKNWSRR 60
           MNRHLCVWLFRHPSLNGYLQCHIQLHSHQFRQIHLDTRLQVFRQNRNCILHLLSKNWSRR
Sbjct: 1   MNRHLCVWLFRHPSLNGYLQCHIQLHSHQFRQIHLDTRLQVFRQNRNCILHLLSKNWSRR 60

Query: 61  YCHQDTKMLWKHKALQKYMENLSKEYQTLEQCLQHIPVNEENRRSLNRRHAELAPLAAIY 120
           YCHQDTKMLWKHKALQKYMENLSKEYQTLEQCLQHIPVNEENRRSLNRRHAELAPLAAIY
Sbjct: 61  YCHQDTKMLWKHKALQKYMENLSKEYQTLEQCLQHIPVNEENRRSLNRRHAELAPLAAIY 120

Query: 121 QEIQETEQAIEELESMCKSLNKQDEKQLQELALEERQTIDQKINMLYNELFQSLVPKEKY 180
           QEIQETEQAIEELESMCKSLNKQDEKQLQELALEERQTIDQKINMLYNELFQSLVPKEKY
Sbjct: 121 QEIQETEQAIEELESMCKSLNKQDEKQLQELALEERQTIDQKINMLYNELFQSLVPKEKY 180

Query: 181 DKNDVILEVTAGRTTGGDICQQFTREIFDMYQNYSCYKHWQFELLNYTPADYGGLHHAAA 240
           DKNDVILEVTAGRTTGGDICQQFTREIFDMYQNYSCYKHWQFELLNYTPADYGGLHHAAA
Sbjct: 181 DKNDVILEVTAGRTTGGDICQQFTREIFDMYQNYSCYKHWQFELLNYTPADYGGLHHAAA 240

Query: 241 RISGDGVYKHLKYEGGIHRVQRIPEVGLSSRMQRIHTGTMSVIVLPQPDEVDVKLDPKDL 300
           RISGDGVYKHLKYEGGIHRVQRIPEVGLSSRMQRIHTGTMSVIVLPQPDEVDVKLDPKDL
Sbjct: 241 RISGDGVYKHLKYEGGIHRVQRIPEVGLSSRMQRIHTGTMSVIVLPQPDEVDVKLDPKDL 300

Query: 301 RIDTFRAKGAGGQHVNKTDSAVRLVHIPTGLVVECQQERSQIKNKEIAFRVLRARLYQQI 360
           RIDTFRAKGAGGQHVNKTDSAVRLVHIPTGLVVECQQERSQIKNKEIAFRVLRARLYQQI
Sbjct: 301 RIDTFRAKGAGGQHVNKTDSAVRLVHIPTGLVVECQQERSQIKNKEIAFRVLRARLYQQI 360

Query: 361 IEKDKRQQQSARKLQVGTRAQSERIRTYNFTQDRVSDHRIAYEVRDIKEFLCGGKGLDQL 420
           IEKDKRQQQSARKLQVGTRAQSERIRTYNFTQDRVSDHRIAYEVRDIKEFLCGGKGLDQL
Sbjct: 361 IEKDKRQQQSARKLQVGTRAQSERIRTYNFTQDRVSDHRIAYEVRDIKEFLCGGKGLDQL 420

Query: 421 IQRLLQSADEEAIAELLDEHLKSAK 445
           IQRLLQSADEEAIAELLDEHLKSAK
Sbjct: 421 IQRLLQSADEEAIAELLDEHLKSAK 445


>gi|166795303 mitochondrial translational release factor 1-like
           isoform a [Homo sapiens]
          Length = 380

 Score =  323 bits (827), Expect = 3e-88
 Identities = 159/324 (49%), Positives = 229/324 (70%), Gaps = 9/324 (2%)

Query: 116 LAAIYQEIQETEQAIEELESMCKSLNKQDEKQLQELALEERQTIDQKINMLYNELFQSLV 175
           L A+ + + E E+ + E E +    N+     L++LA  E     ++I  L +++   LV
Sbjct: 64  LLAVIKLLNEKERELRETEHLLHDENED----LRKLAENEITLCQKEITQLKHQIILLLV 119

Query: 176 PKEKYDKNDVILEVTAGRTTGGDICQQFTREIFDMYQNYSCYKHWQFELLNYTPADYGGL 235
           P E+ D+ND+ILEVTAG   GG     FT EIFDMYQ Y+ +K W FE L Y P++ GGL
Sbjct: 120 PSEETDENDLILEVTAG--VGGQEAMLFTSEIFDMYQQYAAFKRWHFETLEYFPSELGGL 177

Query: 236 HHAAARISGDGVYKHLKYEGGIHRVQRIPEVGLSSRMQRIHTGTMSVIVLPQPDEVDVKL 295
            HA+A I G   Y+H+K+EGG+HRVQR+P+   + +  R+HT TM+V +LPQP E+++ +
Sbjct: 178 RHASASIGGSEAYRHMKFEGGVHRVQRVPK---TEKQGRVHTSTMTVAILPQPTEINLVI 234

Query: 296 DPKDLRIDTFRAKGAGGQHVNKTDSAVRLVHIPTGLVVECQQERSQIKNKEIAFRVLRAR 355
           +PKDLRIDT RA GAGGQHVN TDSAVR+VH+PTG+V ECQQERSQ+KNKE+A   LRA+
Sbjct: 235 NPKDLRIDTKRASGAGGQHVNTTDSAVRIVHLPTGVVSECQQERSQLKNKELAMTKLRAK 294

Query: 356 LYQQIIEKDKRQQQSARKLQVGTRAQSERIRTYNFTQDRVSDHRIAYEVRDIKEFLCGGK 415
           LY   +E++  ++Q+ARK+Q+G++ +SE+IRTYNF Q+RV+DHRI   + D++ F+ G  
Sbjct: 295 LYSMHLEEEINKRQNARKIQIGSKGRSEKIRTYNFPQNRVTDHRINKTLHDLETFMQGDY 354

Query: 416 GLDQLIQRLLQSADEEAIAELLDE 439
            LD+L+Q L + AD E++ E++ +
Sbjct: 355 LLDELVQSLKEYADYESLVEIISQ 378


>gi|166795305 mitochondrial translational release factor 1-like
           isoform b [Homo sapiens]
          Length = 271

 Score =  210 bits (535), Expect = 2e-54
 Identities = 105/214 (49%), Positives = 145/214 (67%), Gaps = 9/214 (4%)

Query: 116 LAAIYQEIQETEQAIEELESMCKSLNKQDEKQLQELALEERQTIDQKINMLYNELFQSLV 175
           L A+ + + E E+ + E E +    N+     L++LA  E     ++I  L +++   LV
Sbjct: 64  LLAVIKLLNEKERELRETEHLLHDENED----LRKLAENEITLCQKEITQLKHQIILLLV 119

Query: 176 PKEKYDKNDVILEVTAGRTTGGDICQQFTREIFDMYQNYSCYKHWQFELLNYTPADYGGL 235
           P E+ D+ND+ILEVTAG   GG     FT EIFDMYQ Y+ +K W FE L Y P++ GGL
Sbjct: 120 PSEETDENDLILEVTAG--VGGQEAMLFTSEIFDMYQQYAAFKRWHFETLEYFPSELGGL 177

Query: 236 HHAAARISGDGVYKHLKYEGGIHRVQRIPEVGLSSRMQRIHTGTMSVIVLPQPDEVDVKL 295
            HA+A I G   Y+H+K+EGG+HRVQR+P+   + +  R+HT TM+V +LPQP E+++ +
Sbjct: 178 RHASASIGGSEAYRHMKFEGGVHRVQRVPK---TEKQGRVHTSTMTVAILPQPTEINLVI 234

Query: 296 DPKDLRIDTFRAKGAGGQHVNKTDSAVRLVHIPT 329
           +PKDLRIDT RA GAGGQHVN TDSAVR+VH+PT
Sbjct: 235 NPKDLRIDTKRASGAGGQHVNTTDSAVRIVHLPT 268


>gi|219879802 hypothetical protein LOC91574 [Homo sapiens]
          Length = 166

 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 32/99 (32%), Positives = 55/99 (55%), Gaps = 8/99 (8%)

Query: 293 VKLDPKDLRIDTFRAKGAGGQHVNKTDSAVRLVHIPTGLVVECQQERSQIKNKEIAFRVL 352
           + LD  +L     +  G GGQ  NKT + V L HIP+G+VV+C Q RS  +N+++A ++L
Sbjct: 53  LSLDENELEEQFVKGHGPGGQATNKTSNCVVLKHIPSGIVVKCHQTRSVDQNRKLARKIL 112

Query: 353 RARL------YQQIIEKDKRQQQSARKLQVGTRAQSERI 385
           + ++          + K+KR  ++A+K Q   +   E +
Sbjct: 113 QEKVDVFYNGENSPVHKEKR--EAAKKKQERKKRAKETL 149


>gi|22748627 hypothetical protein LOC91574 [Homo sapiens]
          Length = 166

 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 32/99 (32%), Positives = 55/99 (55%), Gaps = 8/99 (8%)

Query: 293 VKLDPKDLRIDTFRAKGAGGQHVNKTDSAVRLVHIPTGLVVECQQERSQIKNKEIAFRVL 352
           + LD  +L     +  G GGQ  NKT + V L HIP+G+VV+C Q RS  +N+++A ++L
Sbjct: 53  LSLDENELEEQFVKGHGPGGQATNKTSNCVVLKHIPSGIVVKCHQTRSVDQNRKLARKIL 112

Query: 353 RARL------YQQIIEKDKRQQQSARKLQVGTRAQSERI 385
           + ++          + K+KR  ++A+K Q   +   E +
Sbjct: 113 QEKVDVFYNGENSPVHKEKR--EAAKKKQERKKRAKETL 149


>gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens]
          Length = 284

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 40/133 (30%), Positives = 68/133 (51%), Gaps = 14/133 (10%)

Query: 75  LQKYMENLSKEYQTLEQCLQHIPVNEENRRSLNRR----HAEL----APLAAIYQEIQET 126
           ++KY E++ +  + LEQ  +     E +  SLNRR      EL      LA   Q+++E 
Sbjct: 57  VEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEA 116

Query: 127 EQAIEELESMCKSLN----KQDEK-QLQELALEERQTIDQKINMLYNELFQSLVPKE-KY 180
           E+A +E E   K +     K +EK +LQE+ L+E + I +  +  Y E+ + LV  E + 
Sbjct: 117 EKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGEL 176

Query: 181 DKNDVILEVTAGR 193
           ++++   EV   R
Sbjct: 177 ERSEERAEVAESR 189


>gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens]
          Length = 284

 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 36/114 (31%), Positives = 59/114 (51%), Gaps = 13/114 (11%)

Query: 75  LQKYMENLSKEYQTLEQCLQHIPVNEENRRSLNRR----HAEL----APLAAIYQEIQET 126
           ++KY E++ +  + LEQ  +     E +  SLNRR      EL      LA   Q+++E 
Sbjct: 57  VEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEA 116

Query: 127 EQAIEELESMCKSLN----KQDEK-QLQELALEERQTIDQKINMLYNELFQSLV 175
           E+A +E E   K +     K +EK +LQE+ L+E + I +  +  Y E+ + LV
Sbjct: 117 EKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLV 170


>gi|116235478 establishment of cohesion 1 homolog 1 [Homo sapiens]
          Length = 840

 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 38/150 (25%), Positives = 66/150 (44%), Gaps = 13/150 (8%)

Query: 59  RRYCHQDTKMLWKHKAL----QKYMENLSKEYQTLEQCLQHIPVNEENRRSLNRRHAELA 114
           R Y  + TK     K L     K  E L++  Q L+Q      + E +RRSL  R  +  
Sbjct: 91  RGYSQESTKKKLSQKKLVHENPKANEQLNRRSQRLQQ------LTEVSRRSLRSREIQ-G 143

Query: 115 PLAAIYQEIQETEQAIEELESMCKSLNKQDEKQLQELALEERQTIDQKINMLYNELFQSL 174
            + A+ Q +  T++  E+  S     NK  +K ++   LE +    +  N++ NE+  S 
Sbjct: 144 QVQAVKQSLPPTKK--EQCSSTQSKSNKTSQKHVKRKVLEVKSDSKEDENLVINEVINSP 201

Query: 175 VPKEKYDKNDVILEVTAGRTTGGDICQQFT 204
             K++  ++      ++  T G + C Q T
Sbjct: 202 KGKKRKVEHQTACACSSQCTQGSEKCPQKT 231


>gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens]
          Length = 285

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 38/135 (28%), Positives = 59/135 (43%), Gaps = 13/135 (9%)

Query: 54  SKNWSRRYCHQDTKMLWKHKALQKYMENLSKEYQTLEQCLQHIPVNEENRRSLNRR---- 109
           SK           K+      L KY E L    + LE   +     E    SLNRR    
Sbjct: 37  SKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLV 96

Query: 110 HAEL----APLAAIYQEIQETEQAIEELESMCK-----SLNKQDEKQLQELALEERQTID 160
             EL      LA   Q+++E E+A +E E   K     +L  +++ +LQE+ L+E + I 
Sbjct: 97  EEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIA 156

Query: 161 QKINMLYNELFQSLV 175
           ++ +  Y E+ + LV
Sbjct: 157 EEADRKYEEVARKLV 171


>gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens]
          Length = 284

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 37/126 (29%), Positives = 60/126 (47%), Gaps = 13/126 (10%)

Query: 63  HQDTKMLWKHKALQKYMENLSKEYQTLEQCLQHIPVNEENRRSLNRR----HAEL----A 114
           H   K+      L KY E+L    + LE   +     E +  +LNRR      EL     
Sbjct: 45  HLQKKLKGTEDELDKYSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQE 104

Query: 115 PLAAIYQEIQETEQAIEELESMCKSLN----KQDEK-QLQELALEERQTIDQKINMLYNE 169
            LA   Q+++E E+A +E E   K +     K +EK ++QE+ L+E + I ++ +  Y E
Sbjct: 105 RLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEE 164

Query: 170 LFQSLV 175
           + + LV
Sbjct: 165 VARKLV 170


>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
            sapiens]
          Length = 1843

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 37/155 (23%), Positives = 71/155 (45%), Gaps = 14/155 (9%)

Query: 81   NLSKEYQTL--------EQCLQHIPVNEENRRSLNRRHAELAPLAAIYQEI----QETEQ 128
            NL KE +TL        E C++   + +EN+  + R   ++  L  + +++     +T+Q
Sbjct: 861  NLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQ 920

Query: 129  AIEELESMCKSLNKQDEKQLQELALEERQTIDQKINMLYNELFQSLVPKEKYDKNDVILE 188
               +LE +   L K    + + L  +E+ T D +  +L ++L +S + K    K + I  
Sbjct: 921  MNNDLEKLTHELEKIGLNK-ERLLHDEQSTDDSRYKLLESKL-ESTLKKSLEIKEEKIAA 978

Query: 189  VTAGRTTGGDICQQFTREIFDMYQNYSCYKHWQFE 223
            + A      +  QQ  +E+  + +NY   K  Q E
Sbjct: 979  LEARLEESTNYNQQLRQELKTVKKNYEALKQRQDE 1013



 Score = 37.4 bits (85), Expect = 0.028
 Identities = 23/86 (26%), Positives = 47/86 (54%), Gaps = 1/86 (1%)

Query: 71  KHKALQKYMENLSKEYQTLEQCLQHIPV-NEENRRSLNRRHAELAPLAAIYQEIQETEQA 129
           +++ LQK +EN +K+ Q LE  LQ + + N+  +++L         L  + +E +  EQ 
Sbjct: 764 ENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQE 823

Query: 130 IEELESMCKSLNKQDEKQLQELALEE 155
             +LE   K L K++++  Q+  +++
Sbjct: 824 TSQLEKDKKQLEKENKRLRQQAEIKD 849



 Score = 32.7 bits (73), Expect = 0.68
 Identities = 42/162 (25%), Positives = 66/162 (40%), Gaps = 17/162 (10%)

Query: 38  RLQVFRQNRNCILHLLSKNWSRRYCHQDT--KMLWKHKALQKYMENLSKEYQTLEQCLQH 95
           RLQ   +N N  +  L            T  K L + K   K +E L KE ++LEQ    
Sbjct: 767 RLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQ 826

Query: 96  IPVNEENRRSLNRRHAELAPLAAIYQ-EIQETEQAIEELESMCKSLNKQ----------- 143
           +   E++++ L + +  L   A I    ++E    I  LE   K+L+K+           
Sbjct: 827 L---EKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRL 883

Query: 144 DEKQLQELALEERQTIDQKINMLYNELFQSLVPKEKYDKNDV 185
            E + +   L +R TID K  +   E   S   K +   ND+
Sbjct: 884 KELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDL 925


>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
            sapiens]
          Length = 1870

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 37/155 (23%), Positives = 70/155 (45%), Gaps = 15/155 (9%)

Query: 81   NLSKEYQTL--------EQCLQHIPVNEENRRSLNRRHAELAPLAAIYQEI----QETEQ 128
            NL KE +TL        E C++   + +EN+  + R   ++  L  + +++     +T+Q
Sbjct: 861  NLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQ 920

Query: 129  AIEELESMCKSLNKQDEKQLQELALEERQTIDQKINMLYNELFQSLVPKEKYDKNDVILE 188
               +LE +   L K      +E  L + Q+ D +  +L ++L +S + K    K + I  
Sbjct: 921  MNNDLEKLTHELEKIGLN--KERLLHDEQSTDDRYKLLESKL-ESTLKKSLEIKEEKIAA 977

Query: 189  VTAGRTTGGDICQQFTREIFDMYQNYSCYKHWQFE 223
            + A      +  QQ  +E+  + +NY   K  Q E
Sbjct: 978  LEARLEESTNYNQQLRQELKTVKKNYEALKQRQDE 1012



 Score = 37.4 bits (85), Expect = 0.028
 Identities = 23/86 (26%), Positives = 47/86 (54%), Gaps = 1/86 (1%)

Query: 71  KHKALQKYMENLSKEYQTLEQCLQHIPV-NEENRRSLNRRHAELAPLAAIYQEIQETEQA 129
           +++ LQK +EN +K+ Q LE  LQ + + N+  +++L         L  + +E +  EQ 
Sbjct: 764 ENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQE 823

Query: 130 IEELESMCKSLNKQDEKQLQELALEE 155
             +LE   K L K++++  Q+  +++
Sbjct: 824 TSQLEKDKKQLEKENKRLRQQAEIKD 849



 Score = 32.7 bits (73), Expect = 0.68
 Identities = 42/162 (25%), Positives = 66/162 (40%), Gaps = 17/162 (10%)

Query: 38  RLQVFRQNRNCILHLLSKNWSRRYCHQDT--KMLWKHKALQKYMENLSKEYQTLEQCLQH 95
           RLQ   +N N  +  L            T  K L + K   K +E L KE ++LEQ    
Sbjct: 767 RLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQ 826

Query: 96  IPVNEENRRSLNRRHAELAPLAAIYQ-EIQETEQAIEELESMCKSLNKQ----------- 143
           +   E++++ L + +  L   A I    ++E    I  LE   K+L+K+           
Sbjct: 827 L---EKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRL 883

Query: 144 DEKQLQELALEERQTIDQKINMLYNELFQSLVPKEKYDKNDV 185
            E + +   L +R TID K  +   E   S   K +   ND+
Sbjct: 884 KELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDL 925


>gi|110815815 centlein isoform 1 [Homo sapiens]
          Length = 1406

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 36/130 (27%), Positives = 60/130 (46%), Gaps = 19/130 (14%)

Query: 59   RRYCHQDTKMLWK-----HKALQKYMENLSKEYQTL-EQCLQHIPVNEENRRSLNRRHAE 112
            +R+  +D K   K     +K+  + ++NL K+ +TL E+C       +  ++ LN    E
Sbjct: 1146 KRHLIEDLKFRQKVNLESNKSFSEMLQNLDKKVKTLTEECSNKKVSIDSLKQRLNVAVKE 1205

Query: 113  LAPLAAIYQEIQETEQA-----------IEELESMCKSLNKQDEKQLQELALEERQTID- 160
             +    +YQ+ +E  +            I E ES    +     KQLQELAL+  Q ++ 
Sbjct: 1206 KSQYEQMYQKSKEELEKKDLKLTLLVSRISETESAMAEIETAASKQLQELALQSEQVLEG 1265

Query: 161  -QKINMLYNE 169
             QK  +L NE
Sbjct: 1266 AQKTLLLANE 1275


>gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens]
          Length = 284

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 34/114 (29%), Positives = 54/114 (47%), Gaps = 13/114 (11%)

Query: 75  LQKYMENLSKEYQTLEQCLQHIPVNEENRRSLNRR----HAEL----APLAAIYQEIQET 126
           L KY E L    + LE   +     E +  SLNRR      EL      LA   Q+++E 
Sbjct: 57  LDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEA 116

Query: 127 EQAIEELESMCKSLNKQDEK-----QLQELALEERQTIDQKINMLYNELFQSLV 175
           E+A +E E   K +  + +K     ++QE+ L+E + I +  +  Y E+ + LV
Sbjct: 117 EKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLV 170


>gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens]
          Length = 284

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 34/114 (29%), Positives = 54/114 (47%), Gaps = 13/114 (11%)

Query: 75  LQKYMENLSKEYQTLEQCLQHIPVNEENRRSLNRR----HAEL----APLAAIYQEIQET 126
           L KY E L    + LE   +     E +  SLNRR      EL      LA   Q+++E 
Sbjct: 57  LDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEA 116

Query: 127 EQAIEELESMCKSLNKQDEK-----QLQELALEERQTIDQKINMLYNELFQSLV 175
           E+A +E E   K +  + +K     ++QE+ L+E + I +  +  Y E+ + LV
Sbjct: 117 EKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLV 170


>gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens]
          Length = 284

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 34/114 (29%), Positives = 54/114 (47%), Gaps = 13/114 (11%)

Query: 75  LQKYMENLSKEYQTLEQCLQHIPVNEENRRSLNRR----HAEL----APLAAIYQEIQET 126
           L KY E L    + LE   +     E +  SLNRR      EL      LA   Q+++E 
Sbjct: 57  LDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEA 116

Query: 127 EQAIEELESMCKSLNKQDEK-----QLQELALEERQTIDQKINMLYNELFQSLV 175
           E+A +E E   K +  + +K     ++QE+ L+E + I +  +  Y E+ + LV
Sbjct: 117 EKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLV 170


>gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens]
          Length = 284

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 34/114 (29%), Positives = 54/114 (47%), Gaps = 13/114 (11%)

Query: 75  LQKYMENLSKEYQTLEQCLQHIPVNEENRRSLNRR----HAEL----APLAAIYQEIQET 126
           L KY E L    + LE   +     E +  SLNRR      EL      LA   Q+++E 
Sbjct: 57  LDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEA 116

Query: 127 EQAIEELESMCKSLNKQDEK-----QLQELALEERQTIDQKINMLYNELFQSLV 175
           E+A +E E   K +  + +K     ++QE+ L+E + I +  +  Y E+ + LV
Sbjct: 117 EKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLV 170


>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
            repeats isoform 2 [Homo sapiens]
          Length = 1403

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 29/130 (22%), Positives = 65/130 (50%), Gaps = 14/130 (10%)

Query: 73   KALQKYMENLSKEYQTLEQCLQHIPVNEENRRSLNRRHAELAPLAAIYQEIQETEQAIEE 132
            +AL +  + L+K+ + L Q  ++  V     + +     + + + A+   +Q+    +E+
Sbjct: 1046 RALSRKTDELNKQLKDLSQ--KYTEVKNVKEKLVEENAKQTSEILAVQNLLQKQHVPLEQ 1103

Query: 133  LESMCKSLN------KQDEKQLQELALEERQTIDQKINMLYNE------LFQSLVPKEKY 180
            +E++ KSLN      K++ K +Q    +E+QT+ +   +L N+      L + L  KE +
Sbjct: 1104 VEALKKSLNGTIENLKEELKSMQRCYEKEQQTVTKLHQLLENQKNSSVPLAEHLQIKEAF 1163

Query: 181  DKNDVILEVT 190
            +K   I++ +
Sbjct: 1164 EKEVGIIKAS 1173



 Score = 28.9 bits (63), Expect = 9.9
 Identities = 28/107 (26%), Positives = 49/107 (45%), Gaps = 21/107 (19%)

Query: 71   KHKALQKYMENLSK---EYQTLEQCLQHIPVNE------------ENRRSLNRRHAELAP 115
            K +  Q  ME +SK   E Q  +Q L+ +   E            +    ++  + +LA 
Sbjct: 1177 KEEESQNKMEEVSKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLAN 1236

Query: 116  LAAIYQEIQETEQAIEELESMCKSLNKQDEKQLQELALEERQTIDQK 162
            L   Y+E+ E     E L +  K ++ +DEK+L   ++E+ +  DQK
Sbjct: 1237 LNRKYEEVCE-----EVLHAKKKEISAKDEKELLHFSIEQ-EIKDQK 1277


>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
            repeats isoform 1 [Homo sapiens]
          Length = 1416

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 29/130 (22%), Positives = 65/130 (50%), Gaps = 14/130 (10%)

Query: 73   KALQKYMENLSKEYQTLEQCLQHIPVNEENRRSLNRRHAELAPLAAIYQEIQETEQAIEE 132
            +AL +  + L+K+ + L Q  ++  V     + +     + + + A+   +Q+    +E+
Sbjct: 1059 RALSRKTDELNKQLKDLSQ--KYTEVKNVKEKLVEENAKQTSEILAVQNLLQKQHVPLEQ 1116

Query: 133  LESMCKSLN------KQDEKQLQELALEERQTIDQKINMLYNE------LFQSLVPKEKY 180
            +E++ KSLN      K++ K +Q    +E+QT+ +   +L N+      L + L  KE +
Sbjct: 1117 VEALKKSLNGTIENLKEELKSMQRCYEKEQQTVTKLHQLLENQKNSSVPLAEHLQIKEAF 1176

Query: 181  DKNDVILEVT 190
            +K   I++ +
Sbjct: 1177 EKEVGIIKAS 1186



 Score = 28.9 bits (63), Expect = 9.9
 Identities = 28/107 (26%), Positives = 49/107 (45%), Gaps = 21/107 (19%)

Query: 71   KHKALQKYMENLSK---EYQTLEQCLQHIPVNE------------ENRRSLNRRHAELAP 115
            K +  Q  ME +SK   E Q  +Q L+ +   E            +    ++  + +LA 
Sbjct: 1190 KEEESQNKMEEVSKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLAN 1249

Query: 116  LAAIYQEIQETEQAIEELESMCKSLNKQDEKQLQELALEERQTIDQK 162
            L   Y+E+ E     E L +  K ++ +DEK+L   ++E+ +  DQK
Sbjct: 1250 LNRKYEEVCE-----EVLHAKKKEISAKDEKELLHFSIEQ-EIKDQK 1290


>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
            sapiens]
          Length = 1939

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 80/416 (19%), Positives = 160/416 (38%), Gaps = 51/416 (12%)

Query: 35   LDTRLQVFRQNRNCILHLLSKNWSRRYCHQDTKMLWKHKALQKYMENLSKEYQTLEQCLQ 94
            ++ R  +F    N    +  K+W     +   K L K    +K M N+ +E+   E+  +
Sbjct: 809  VERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEF---EKTKE 865

Query: 95   HIPVNEENRRSLNRRHAELAPLAAIYQ-EIQETEQAIEELESMCKSLNKQDEKQLQELAL 153
             +   E  R+ L  +   L       Q ++Q    ++ + E  C  L K   K   E  +
Sbjct: 866  ELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKT--KIQLEAKI 923

Query: 154  EERQTIDQKINMLYNELFQSLVPKEKYDKNDVILEVTAGRTTGGDICQQFTREIFDM--- 210
            +E                   V +   D+ ++  E+TA +    D C +  ++I D+   
Sbjct: 924  KE-------------------VTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 964

Query: 211  YQNYSCYKHWQFELLNYTPADYGGLHHAAARISGDGVYKHLKYEGGIHRVQRIPEVGLSS 270
                   KH     +     +  GL    A+++        K +  +    +     L +
Sbjct: 965  LAKVEKEKHATENKVKNLTEEMAGLDETIAKLT--------KEKKALQEAHQQTLDDLQA 1016

Query: 271  RMQRIHTGTMSVIVLPQP-DEVDVKLD-PKDLRIDTFRAKGAGGQHVNKTDSAVRLVHIP 328
               +++T T + I L Q  D+++  L+  K +R+D  RAK        K +  ++L    
Sbjct: 1017 EEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAK-------RKLEGDLKLAQES 1069

Query: 329  T-GLVVECQQERSQIKNKEIAFRVLRARLYQQIIEKDKRQQQSARKLQVGTRAQSERIRT 387
            T  +  + QQ   ++K KE     L++++  +      + Q+  ++LQ       E I  
Sbjct: 1070 TMDIENDKQQLDEKLKKKEFEMSGLQSKIEDE-QALGMQLQKKIKELQARIEELEEEIEA 1128

Query: 388  YNFTQDRVSDHR--IAYEVRDIKEFL--CGGKGLDQLIQRLLQSADEEAIAELLDE 439
               ++ +    R  ++ E+ +I E L   GG    Q+     + A+ + +   L+E
Sbjct: 1129 ERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEE 1184


>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
            transmembrane signal), 1 [Homo sapiens]
          Length = 3259

 Score = 38.9 bits (89), Expect = 0.010
 Identities = 25/96 (26%), Positives = 48/96 (50%), Gaps = 5/96 (5%)

Query: 64   QDTKMLWKHKALQKYMENLSKEYQTLE---QCLQHI--PVNEENRRSLNRRHAELAPLAA 118
            + T+   KHK LQK  E L + Y+ +    + +QH+   V +E +    +  +  A    
Sbjct: 1600 ESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKE 1659

Query: 119  IYQEIQETEQAIEELESMCKSLNKQDEKQLQELALE 154
              +++QE EQ +EE++   +   K  ++++ EL  E
Sbjct: 1660 TEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEE 1695



 Score = 36.2 bits (82), Expect = 0.062
 Identities = 36/142 (25%), Positives = 69/142 (48%), Gaps = 23/142 (16%)

Query: 75  LQKYMENLSKEYQTLEQCLQHIPVNEENRRSLNRRH-AELAPLAAIYQEIQETEQAIEEL 133
           LQ+ M +L ++++   Q    +   E    +L ++H AE+    +    +Q+T Q   EL
Sbjct: 338 LQEEMHHLLEQFEQAGQAQAEL---ESRYSALEQKHKAEMEEKTSHILSLQKTGQ---EL 391

Query: 134 ESMCKSLNKQDEKQLQ---ELALEERQTIDQKINMLYNE-----LFQSLVPKEKYDKNDV 185
           +S C +L  Q+ K LQ   E A++  QTI Q  + L  +      F + +P ++++    
Sbjct: 392 QSACDALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQHE---- 447

Query: 186 ILEVTAGRTTGGDICQQFTREI 207
               TA +T+  D+  + T+ +
Sbjct: 448 ----TASQTSFPDVYNEGTQAV 465



 Score = 31.2 bits (69), Expect = 2.0
 Identities = 26/102 (25%), Positives = 48/102 (47%), Gaps = 19/102 (18%)

Query: 61   YCHQDTKMLWKHKALQKYMENLSKEYQTLEQCLQHIPVNEENRRSLNRRHAELAPLAAIY 120
            YC   T    K++ L+  M+NL K       C+  +   EE ++ L +   ++       
Sbjct: 1940 YCQDVTDAQIKNELLESEMKNLKK-------CVSEL---EEEKQQLVKEKTKV------- 1982

Query: 121  QEIQETEQAIEELESMCKSL-NKQDEKQLQELALEERQTIDQ 161
             E +  ++ +E+++   K   NK   K+LQEL  E++Q + Q
Sbjct: 1983 -ESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQ 2023


>gi|114155146 tropomyosin 3 isoform 3 [Homo sapiens]
          Length = 247

 Score = 38.5 bits (88), Expect = 0.012
 Identities = 29/107 (27%), Positives = 54/107 (50%), Gaps = 12/107 (11%)

Query: 116 LAAIYQEIQETEQAIEELESMCK-----SLNKQDEKQLQELALEERQTIDQKINMLYNEL 170
           LA   Q+++E E+A +E E   K     +L  +++ +LQE+ L+E + I ++ +  Y E+
Sbjct: 70  LATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEV 129

Query: 171 FQSLVPKE-KYDKNDVILEVTAGRTTGGDICQQFTREIFDMYQNYSC 216
            + LV  E   ++ +   E+   R      C++   +I  M QN  C
Sbjct: 130 ARKLVIIEGDLERTEERAELAESR------CREMDEQIRLMDQNLKC 170


>gi|24119203 tropomyosin 3 isoform 2 [Homo sapiens]
          Length = 248

 Score = 38.5 bits (88), Expect = 0.012
 Identities = 29/107 (27%), Positives = 54/107 (50%), Gaps = 12/107 (11%)

Query: 116 LAAIYQEIQETEQAIEELESMCK-----SLNKQDEKQLQELALEERQTIDQKINMLYNEL 170
           LA   Q+++E E+A +E E   K     +L  +++ +LQE+ L+E + I ++ +  Y E+
Sbjct: 70  LATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEV 129

Query: 171 FQSLVPKE-KYDKNDVILEVTAGRTTGGDICQQFTREIFDMYQNYSC 216
            + LV  E   ++ +   E+   R      C++   +I  M QN  C
Sbjct: 130 ARKLVIIEGDLERTEERAELAESR------CREMDEQIRLMDQNLKC 170


>gi|50658069 phosphodiesterase 4D interacting protein isoform 2
           [Homo sapiens]
          Length = 969

 Score = 37.7 bits (86), Expect = 0.021
 Identities = 27/119 (22%), Positives = 62/119 (52%), Gaps = 7/119 (5%)

Query: 72  HKALQKYMENLSKEYQTLEQCLQHIPVN-----EENRRSLNRRHAEL-APLAAIYQEIQE 125
           ++ L +++ +L KE  +L+  +  +        E +R  + +R+ EL   + ++ +E+Q+
Sbjct: 5   YRTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQD 64

Query: 126 TEQAIEELESMCKSLNKQDEKQLQELALEERQTIDQKINMLYNELFQSLVPKEKYDKND 184
            +Q +++  +  ++LN Q+E +L+    EERQ   + +  L     Q L  + +  KN+
Sbjct: 65  KKQHLDKTWADVENLNSQNEAELRR-QFEERQQETEHVYELLENKIQLLQEESRLAKNE 122


>gi|157311604 phosphodiesterase 4D interacting protein isoform 1
           [Homo sapiens]
          Length = 2346

 Score = 37.7 bits (86), Expect = 0.021
 Identities = 27/119 (22%), Positives = 62/119 (52%), Gaps = 7/119 (5%)

Query: 72  HKALQKYMENLSKEYQTLEQCLQHIPVN-----EENRRSLNRRHAEL-APLAAIYQEIQE 125
           ++ L +++ +L KE  +L+  +  +        E +R  + +R+ EL   + ++ +E+Q+
Sbjct: 5   YRTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQD 64

Query: 126 TEQAIEELESMCKSLNKQDEKQLQELALEERQTIDQKINMLYNELFQSLVPKEKYDKND 184
            +Q +++  +  ++LN Q+E +L+    EERQ   + +  L     Q L  + +  KN+
Sbjct: 65  KKQHLDKTWADVENLNSQNEAELRR-QFEERQQETEHVYELLENKIQLLQEESRLAKNE 122


>gi|50658077 phosphodiesterase 4D interacting protein isoform 4
           [Homo sapiens]
          Length = 173

 Score = 37.7 bits (86), Expect = 0.021
 Identities = 27/119 (22%), Positives = 62/119 (52%), Gaps = 7/119 (5%)

Query: 72  HKALQKYMENLSKEYQTLEQCLQHIPVN-----EENRRSLNRRHAEL-APLAAIYQEIQE 125
           ++ L +++ +L KE  +L+  +  +        E +R  + +R+ EL   + ++ +E+Q+
Sbjct: 5   YRTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQD 64

Query: 126 TEQAIEELESMCKSLNKQDEKQLQELALEERQTIDQKINMLYNELFQSLVPKEKYDKND 184
            +Q +++  +  ++LN Q+E +L+    EERQ   + +  L     Q L  + +  KN+
Sbjct: 65  KKQHLDKTWADVENLNSQNEAELRR-QFEERQQETEHVYELLENKIQLLQEESRLAKNE 122


>gi|50658075 phosphodiesterase 4D interacting protein isoform 3
           [Homo sapiens]
          Length = 310

 Score = 37.0 bits (84), Expect = 0.036
 Identities = 27/115 (23%), Positives = 60/115 (52%), Gaps = 7/115 (6%)

Query: 76  QKYMENLSKEYQTLEQCLQHIPVN-----EENRRSLNRRHAEL-APLAAIYQEIQETEQA 129
           +K++ +L KE  +L+  +  +        E +R  + +R+ EL   + ++ +E+Q+ +Q 
Sbjct: 146 EKHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQH 205

Query: 130 IEELESMCKSLNKQDEKQLQELALEERQTIDQKINMLYNELFQSLVPKEKYDKND 184
           +++  +  ++LN Q+E +L+    EERQ   + +  L     Q L  + +  KN+
Sbjct: 206 LDKTWADVENLNSQNEAELRR-QFEERQQETEHVYELLENKIQLLQEESRLAKNE 259


>gi|56961680 coiled-coil domain containing 147 [Homo sapiens]
          Length = 872

 Score = 37.0 bits (84), Expect = 0.036
 Identities = 28/123 (22%), Positives = 59/123 (47%), Gaps = 9/123 (7%)

Query: 73  KALQKYMENLSKEYQTLEQCLQHIPVNEENRRSLNRRHAELAPLAAIYQEIQETEQAIEE 132
           KALQ+Y++   +E Q LEQ L       + ++ LN R A+   L        + +Q  E+
Sbjct: 240 KALQQYVQKSKEELQKLEQQL-------KEQKILNERAAK--ELEQFQMRNAKLQQENEQ 290

Query: 133 LESMCKSLNKQDEKQLQELALEERQTIDQKINMLYNELFQSLVPKEKYDKNDVILEVTAG 192
              +C+ L+++++++  EL  +E +    ++++      +  + K+ +   D   EV   
Sbjct: 291 HSLVCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKLHHTEDQKAEVEQH 350

Query: 193 RTT 195
           + T
Sbjct: 351 KET 353


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
            sapiens]
          Length = 1935

 Score = 36.2 bits (82), Expect = 0.062
 Identities = 69/347 (19%), Positives = 142/347 (40%), Gaps = 38/347 (10%)

Query: 116  LAAIYQEIQETEQAIEELES--------MCKSLNKQDEKQLQELALEE-----RQTIDQK 162
            +A++ +E    ++A+E+ E+        M   L ++++ QLQ  A ++      +  DQ 
Sbjct: 849  MASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQL 908

Query: 163  I-NMLYNELFQSLVPKEKYDKNDVILEVTAGRTTGGDICQQFTREIFDM---YQNYSCYK 218
            I N +  E     + +   D+ ++  E+TA +    D C +  R+I D+          K
Sbjct: 909  IKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEK 968

Query: 219  HWQFELLNYTPADYGGLHHAAARISGDGVYKHLKYEGGIHRVQRIPEVGLSSRMQRIHTG 278
            H     +     +  GL    A+++        K +  +    +     L +   +++T 
Sbjct: 969  HATENKVKNLTEEMAGLDEIIAKLT--------KEKKALQEAHQQALDDLQAEEDKVNTL 1020

Query: 279  TMSVIVLPQP-DEVDVKLD-PKDLRIDTFRAKGAGGQHVNKTDSAVRLVHIPTGLVVECQ 336
            T + + L Q  D+++  L+  K +R+D  RAK      +  T  ++        L  + Q
Sbjct: 1021 TKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESI------MDLENDKQ 1074

Query: 337  QERSQIKNKEIAFRVLRARLYQQIIEKDKRQQQSARKLQVGTRAQSERIRTYNFTQDRVS 396
            Q   ++K K+     L AR+  +      + Q+  ++LQ       E +      + +V 
Sbjct: 1075 QLDERLKKKDFELNALNARIEDE-QALGSQLQKKLKELQARIEELEEELEAERTARAKVE 1133

Query: 397  DHR--IAYEVRDIKEFL--CGGKGLDQLIQRLLQSADEEAIAELLDE 439
              R  ++ E+ +I E L   GG    Q+     + A+ + +   L+E
Sbjct: 1134 KLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEE 1180



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 22/101 (21%), Positives = 45/101 (44%), Gaps = 8/101 (7%)

Query: 57   WSRRYCHQDTKMLWKHKALQKYMENLSKEYQTLEQCLQHIPVNEENRRSLNRRHAELAPL 116
            W ++Y    +++    K  +     L K     E+ L+H+   +   ++L    ++L   
Sbjct: 1456 WKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLT-- 1513

Query: 117  AAIYQEIQETEQAIEELESMCKSLNKQDEKQLQELALEERQ 157
                +++  + + I ELE + K L  + EK   + ALEE +
Sbjct: 1514 ----EQLGSSGKTIHELEKVRKQL--EAEKMELQSALEEAE 1548


>gi|221139761 zinc finger protein 853 [Homo sapiens]
          Length = 659

 Score = 35.8 bits (81), Expect = 0.081
 Identities = 44/176 (25%), Positives = 74/176 (42%), Gaps = 21/176 (11%)

Query: 19  LQCHIQLHSHQFRQ----IHLDTRLQVFRQNRNCILHLLSKNWSR---RYCHQDTKMLWK 71
           LQ   QL   QF+Q    +    +L + +Q       LL +  ++   +   Q    L +
Sbjct: 217 LQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQ 276

Query: 72  HKALQKYMENLSKEYQTL---------EQCLQHIPVNEENRRSLNRRHAELAPLAAIYQE 122
              LQ+  +   ++ Q L         +Q LQ  P+  E    +     EL P+    + 
Sbjct: 277 QLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVE---LELMPVDLGSE- 332

Query: 123 IQETEQAIEELESMCKSLNKQDEKQLQELALEERQTIDQKINMLYNELFQSLVPKE 178
            QE EQ  +ELE   +   +Q+++QLQ    EE Q ++Q++     +L Q  V  E
Sbjct: 333 -QELEQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLE 387



 Score = 29.6 bits (65), Expect = 5.8
 Identities = 30/154 (19%), Positives = 64/154 (41%), Gaps = 16/154 (10%)

Query: 51  HLLSKNWSRRYCHQDTKMLWKHKALQKYMENLSKEYQTLEQCLQHIPVNEENRRSLNRRH 110
           HL  +   ++   Q    L + K    + + L  E Q + Q  Q  P   + ++ L ++ 
Sbjct: 115 HLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQ 174

Query: 111 AELAPLAA-----------IYQEIQETEQAIEELESMCKSLNKQDEKQLQELALEERQTI 159
            +L    A           + Q++QE +   ++ E + +    Q ++QLQ+   +++Q  
Sbjct: 175 EQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQ 234

Query: 160 DQKINML-----YNELFQSLVPKEKYDKNDVILE 188
            Q+   L       +L Q L+ +++      +LE
Sbjct: 235 LQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLE 268


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.135    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,277,998
Number of Sequences: 37866
Number of extensions: 718540
Number of successful extensions: 3491
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 253
Number of HSP's that attempted gapping in prelim test: 3120
Number of HSP's gapped (non-prelim): 680
length of query: 445
length of database: 18,247,518
effective HSP length: 105
effective length of query: 340
effective length of database: 14,271,588
effective search space: 4852339920
effective search space used: 4852339920
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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