Guide to the Human Genome
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Search of human proteins with 34577096

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|34577096 ring finger protein 14 isoform 2 [Homo sapiens]
         (348 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|34577102 ring finger protein 14 isoform 1 [Homo sapiens]           736   0.0  
gi|34577100 ring finger protein 14 isoform 1 [Homo sapiens]           736   0.0  
gi|34577098 ring finger protein 14 isoform 1 [Homo sapiens]           736   0.0  
gi|34577096 ring finger protein 14 isoform 2 [Homo sapiens]           736   0.0  
gi|4757762 ring finger protein 14 isoform 1 [Homo sapiens]            736   0.0  
gi|50284696 IBR domain containing 2 [Homo sapiens]                    108   5e-24
gi|5453557 ariadne homolog 2 [Homo sapiens]                           101   1e-21
gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding pro...    96   4e-20
gi|38045938 ring finger protein 144 [Homo sapiens]                     96   4e-20
gi|148596953 ankyrin repeat and IBR domain containing 1 [Homo sa...    94   2e-19
gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo...    91   2e-18
gi|188219579 ring finger protein 19B isoform b [Homo sapiens]          78   1e-14
gi|188219577 ring finger protein 19B isoform a [Homo sapiens]          78   1e-14
gi|169790973 parkin isoform 3 [Homo sapiens]                           77   3e-14
gi|169790971 parkin isoform 2 [Homo sapiens]                           77   3e-14
gi|169790969 parkin isoform 1 [Homo sapiens]                           77   3e-14
gi|35493801 ring finger protein 19 [Homo sapiens]                      76   4e-14
gi|35493782 ring finger protein 19 [Homo sapiens]                      76   4e-14
gi|5454168 RanBP-type and C3HC4-type zinc finger containing 1 is...    68   1e-11
gi|144953898 RanBP-type and C3HC4-type zinc finger containing 1 ...    68   1e-11
gi|46370057 ring finger protein 216 isoform b [Homo sapiens]           64   2e-10
gi|46358403 ring finger protein 216 isoform a [Homo sapiens]           64   2e-10
gi|22749145 ring finger protein 217 [Homo sapiens]                     49   7e-06
gi|109150431 ring finger protein 31 [Homo sapiens]                     47   2e-05
gi|117606347 F-box protein 43 isoform a [Homo sapiens]                 47   3e-05
gi|117606351 F-box protein 43 isoform b [Homo sapiens]                 47   3e-05
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s...    42   0.001
gi|32454739 tripartite motif-containing 3 [Homo sapiens]               39   0.007
gi|32454737 tripartite motif-containing 3 [Homo sapiens]               39   0.007
gi|56605981 tripartite motif-containing 72 [Homo sapiens]              35   0.076

>gi|34577102 ring finger protein 14 isoform 1 [Homo sapiens]
          Length = 474

 Score =  736 bits (1899), Expect = 0.0
 Identities = 348/348 (100%), Positives = 348/348 (100%)

Query: 1   MQFLKEETLAYLNIVSPFELKIGSQKKVQRRTAQASPNTELDFGGAAGSDVDQEEIVDER 60
           MQFLKEETLAYLNIVSPFELKIGSQKKVQRRTAQASPNTELDFGGAAGSDVDQEEIVDER
Sbjct: 127 MQFLKEETLAYLNIVSPFELKIGSQKKVQRRTAQASPNTELDFGGAAGSDVDQEEIVDER 186

Query: 61  AVQDVESLSNLIQEILDFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFLECRHVYCKAC 120
           AVQDVESLSNLIQEILDFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFLECRHVYCKAC
Sbjct: 187 AVQDVESLSNLIQEILDFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFLECRHVYCKAC 246

Query: 121 LKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQVKELVEAELFARYDRLLLQSSLDLMADV 180
           LKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQVKELVEAELFARYDRLLLQSSLDLMADV
Sbjct: 247 LKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQVKELVEAELFARYDRLLLQSSLDLMADV 306

Query: 181 VYCPRPCCQLPVMQEPGCTMGICSSCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQ 240
           VYCPRPCCQLPVMQEPGCTMGICSSCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQ
Sbjct: 307 VYCPRPCCQLPVMQEPGCTMGICSSCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQ 366

Query: 241 ADEANKRLLDQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCM 300
           ADEANKRLLDQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCM
Sbjct: 367 ADEANKRLLDQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCM 426

Query: 301 QYFCWICMGSLSRANPYKHFNDPGSPCFNRLFYAVDVDDDIWEDEVED 348
           QYFCWICMGSLSRANPYKHFNDPGSPCFNRLFYAVDVDDDIWEDEVED
Sbjct: 427 QYFCWICMGSLSRANPYKHFNDPGSPCFNRLFYAVDVDDDIWEDEVED 474


>gi|34577100 ring finger protein 14 isoform 1 [Homo sapiens]
          Length = 474

 Score =  736 bits (1899), Expect = 0.0
 Identities = 348/348 (100%), Positives = 348/348 (100%)

Query: 1   MQFLKEETLAYLNIVSPFELKIGSQKKVQRRTAQASPNTELDFGGAAGSDVDQEEIVDER 60
           MQFLKEETLAYLNIVSPFELKIGSQKKVQRRTAQASPNTELDFGGAAGSDVDQEEIVDER
Sbjct: 127 MQFLKEETLAYLNIVSPFELKIGSQKKVQRRTAQASPNTELDFGGAAGSDVDQEEIVDER 186

Query: 61  AVQDVESLSNLIQEILDFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFLECRHVYCKAC 120
           AVQDVESLSNLIQEILDFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFLECRHVYCKAC
Sbjct: 187 AVQDVESLSNLIQEILDFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFLECRHVYCKAC 246

Query: 121 LKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQVKELVEAELFARYDRLLLQSSLDLMADV 180
           LKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQVKELVEAELFARYDRLLLQSSLDLMADV
Sbjct: 247 LKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQVKELVEAELFARYDRLLLQSSLDLMADV 306

Query: 181 VYCPRPCCQLPVMQEPGCTMGICSSCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQ 240
           VYCPRPCCQLPVMQEPGCTMGICSSCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQ
Sbjct: 307 VYCPRPCCQLPVMQEPGCTMGICSSCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQ 366

Query: 241 ADEANKRLLDQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCM 300
           ADEANKRLLDQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCM
Sbjct: 367 ADEANKRLLDQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCM 426

Query: 301 QYFCWICMGSLSRANPYKHFNDPGSPCFNRLFYAVDVDDDIWEDEVED 348
           QYFCWICMGSLSRANPYKHFNDPGSPCFNRLFYAVDVDDDIWEDEVED
Sbjct: 427 QYFCWICMGSLSRANPYKHFNDPGSPCFNRLFYAVDVDDDIWEDEVED 474


>gi|34577098 ring finger protein 14 isoform 1 [Homo sapiens]
          Length = 474

 Score =  736 bits (1899), Expect = 0.0
 Identities = 348/348 (100%), Positives = 348/348 (100%)

Query: 1   MQFLKEETLAYLNIVSPFELKIGSQKKVQRRTAQASPNTELDFGGAAGSDVDQEEIVDER 60
           MQFLKEETLAYLNIVSPFELKIGSQKKVQRRTAQASPNTELDFGGAAGSDVDQEEIVDER
Sbjct: 127 MQFLKEETLAYLNIVSPFELKIGSQKKVQRRTAQASPNTELDFGGAAGSDVDQEEIVDER 186

Query: 61  AVQDVESLSNLIQEILDFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFLECRHVYCKAC 120
           AVQDVESLSNLIQEILDFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFLECRHVYCKAC
Sbjct: 187 AVQDVESLSNLIQEILDFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFLECRHVYCKAC 246

Query: 121 LKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQVKELVEAELFARYDRLLLQSSLDLMADV 180
           LKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQVKELVEAELFARYDRLLLQSSLDLMADV
Sbjct: 247 LKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQVKELVEAELFARYDRLLLQSSLDLMADV 306

Query: 181 VYCPRPCCQLPVMQEPGCTMGICSSCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQ 240
           VYCPRPCCQLPVMQEPGCTMGICSSCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQ
Sbjct: 307 VYCPRPCCQLPVMQEPGCTMGICSSCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQ 366

Query: 241 ADEANKRLLDQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCM 300
           ADEANKRLLDQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCM
Sbjct: 367 ADEANKRLLDQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCM 426

Query: 301 QYFCWICMGSLSRANPYKHFNDPGSPCFNRLFYAVDVDDDIWEDEVED 348
           QYFCWICMGSLSRANPYKHFNDPGSPCFNRLFYAVDVDDDIWEDEVED
Sbjct: 427 QYFCWICMGSLSRANPYKHFNDPGSPCFNRLFYAVDVDDDIWEDEVED 474


>gi|34577096 ring finger protein 14 isoform 2 [Homo sapiens]
          Length = 348

 Score =  736 bits (1899), Expect = 0.0
 Identities = 348/348 (100%), Positives = 348/348 (100%)

Query: 1   MQFLKEETLAYLNIVSPFELKIGSQKKVQRRTAQASPNTELDFGGAAGSDVDQEEIVDER 60
           MQFLKEETLAYLNIVSPFELKIGSQKKVQRRTAQASPNTELDFGGAAGSDVDQEEIVDER
Sbjct: 1   MQFLKEETLAYLNIVSPFELKIGSQKKVQRRTAQASPNTELDFGGAAGSDVDQEEIVDER 60

Query: 61  AVQDVESLSNLIQEILDFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFLECRHVYCKAC 120
           AVQDVESLSNLIQEILDFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFLECRHVYCKAC
Sbjct: 61  AVQDVESLSNLIQEILDFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFLECRHVYCKAC 120

Query: 121 LKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQVKELVEAELFARYDRLLLQSSLDLMADV 180
           LKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQVKELVEAELFARYDRLLLQSSLDLMADV
Sbjct: 121 LKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQVKELVEAELFARYDRLLLQSSLDLMADV 180

Query: 181 VYCPRPCCQLPVMQEPGCTMGICSSCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQ 240
           VYCPRPCCQLPVMQEPGCTMGICSSCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQ
Sbjct: 181 VYCPRPCCQLPVMQEPGCTMGICSSCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQ 240

Query: 241 ADEANKRLLDQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCM 300
           ADEANKRLLDQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCM
Sbjct: 241 ADEANKRLLDQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCM 300

Query: 301 QYFCWICMGSLSRANPYKHFNDPGSPCFNRLFYAVDVDDDIWEDEVED 348
           QYFCWICMGSLSRANPYKHFNDPGSPCFNRLFYAVDVDDDIWEDEVED
Sbjct: 301 QYFCWICMGSLSRANPYKHFNDPGSPCFNRLFYAVDVDDDIWEDEVED 348


>gi|4757762 ring finger protein 14 isoform 1 [Homo sapiens]
          Length = 474

 Score =  736 bits (1899), Expect = 0.0
 Identities = 348/348 (100%), Positives = 348/348 (100%)

Query: 1   MQFLKEETLAYLNIVSPFELKIGSQKKVQRRTAQASPNTELDFGGAAGSDVDQEEIVDER 60
           MQFLKEETLAYLNIVSPFELKIGSQKKVQRRTAQASPNTELDFGGAAGSDVDQEEIVDER
Sbjct: 127 MQFLKEETLAYLNIVSPFELKIGSQKKVQRRTAQASPNTELDFGGAAGSDVDQEEIVDER 186

Query: 61  AVQDVESLSNLIQEILDFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFLECRHVYCKAC 120
           AVQDVESLSNLIQEILDFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFLECRHVYCKAC
Sbjct: 187 AVQDVESLSNLIQEILDFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFLECRHVYCKAC 246

Query: 121 LKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQVKELVEAELFARYDRLLLQSSLDLMADV 180
           LKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQVKELVEAELFARYDRLLLQSSLDLMADV
Sbjct: 247 LKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQVKELVEAELFARYDRLLLQSSLDLMADV 306

Query: 181 VYCPRPCCQLPVMQEPGCTMGICSSCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQ 240
           VYCPRPCCQLPVMQEPGCTMGICSSCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQ
Sbjct: 307 VYCPRPCCQLPVMQEPGCTMGICSSCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQ 366

Query: 241 ADEANKRLLDQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCM 300
           ADEANKRLLDQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCM
Sbjct: 367 ADEANKRLLDQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCM 426

Query: 301 QYFCWICMGSLSRANPYKHFNDPGSPCFNRLFYAVDVDDDIWEDEVED 348
           QYFCWICMGSLSRANPYKHFNDPGSPCFNRLFYAVDVDDDIWEDEVED
Sbjct: 427 QYFCWICMGSLSRANPYKHFNDPGSPCFNRLFYAVDVDDDIWEDEVED 474


>gi|50284696 IBR domain containing 2 [Homo sapiens]
          Length = 303

 Score =  108 bits (271), Expect = 5e-24
 Identities = 67/247 (27%), Positives = 107/247 (43%), Gaps = 35/247 (14%)

Query: 91  LFLCSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVAT- 149
           L  C +C CE+   +     EC+ ++C ACLK Y ++ IR+G    + CP+  C +  T 
Sbjct: 27  LITCKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGCGSPITCPDMVCLNHGTL 86

Query: 150 -PGQVKELVEAELFARYDRLLLQSSLDLMADVVYCPRPCCQ--LPV-MQEPGCTMGI-CS 204
              ++  LV  + F  Y RL  +  + L     +CP   CQ   PV   +PG  + + C 
Sbjct: 87  QEAEIACLVPVDQFQLYQRLKFEREVHLDPYRTWCPVADCQTVCPVASSDPGQPVLVECP 146

Query: 205 SCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEE 264
           SC+  FC+ C+  +H    C+ +   ++   +  L   +A                    
Sbjct: 147 SCHLKFCSCCKDAWHAEVSCRDSQPIVLPTEHRALFGTDA-------------------- 186

Query: 265 MESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMGSLSRANPYKHFNDPG 324
                  E   K CP C   IE+ +GC +M C  C   FCW C+ +L      +H++   
Sbjct: 187 -------EAPIKQCPVCRVYIERNEGCAQMMCKNCKHTFCWYCLQNLDNDIFLRHYDK-- 237

Query: 325 SPCFNRL 331
            PC N+L
Sbjct: 238 GPCRNKL 244


>gi|5453557 ariadne homolog 2 [Homo sapiens]
          Length = 493

 Score =  101 bits (251), Expect = 1e-21
 Identities = 56/218 (25%), Positives = 96/218 (44%), Gaps = 30/218 (13%)

Query: 94  CSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQV 153
           C++C  + +  E +  L C+H +C++C + +  + ++DG    ++C    CP       V
Sbjct: 139 CAVCM-QFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFV 197

Query: 154 KELV-EAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPV-MQEPGCTMGICSSCNFAFC 211
             L+   EL  +Y R L +  ++    +  CP   C + + +QEP      C+ CN  FC
Sbjct: 198 FPLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQEPRARRVQCNRCNEVFC 257

Query: 212 TLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKEWL 271
             CR  YH  + C                              ++ + K  ++ E+  ++
Sbjct: 258 FKCRQMYHAPTDCATI---------------------------RKWLTKCADDSETANYI 290

Query: 272 EKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMG 309
             ++K CP C   IEK  GCN M C+ C   FCW+C+G
Sbjct: 291 SAHTKDCPKCNICIEKNGGCNHMQCSKCKHDFCWMCLG 328



 Score = 29.6 bits (65), Expect = 4.2
 Identities = 14/48 (29%), Positives = 21/48 (43%)

Query: 77  DFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFLECRHVYCKACLKDY 124
           D + A  I         C+IC  +  G   M   +C+H +C  CL D+
Sbjct: 283 DSETANYISAHTKDCPKCNICIEKNGGCNHMQCSKCKHDFCWMCLGDW 330


>gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding
           protein homolog 1 [Homo sapiens]
          Length = 557

 Score = 96.3 bits (238), Expect = 4e-20
 Identities = 60/222 (27%), Positives = 92/222 (41%), Gaps = 36/222 (16%)

Query: 94  CSICFCEKLGSECMYF--LECRHVYCKACLKDYFEIQI-RDGQVQCLNCPEPKCPSVATP 150
           C IC+     S   YF  LEC H +C  C  +Y   +I  +G  Q ++CP   C  +   
Sbjct: 186 CQICYLNYPNS---YFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDD 242

Query: 151 GQVKELV-EAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQEPGCTMGICSSCNFA 209
             V  L+ ++++  +Y  L+  S ++    + +CP P C   V  +      +   C   
Sbjct: 243 NTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKCGRQ 302

Query: 210 FCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKE 269
           FC  C   +H    CK                           + K+ I+K  ++ E+  
Sbjct: 303 FCFNCGENWHDPVKCK---------------------------WLKKWIKKCDDDSETSN 335

Query: 270 WLEKNSKSCPCCGTPIEKLDGCNKMTC--TGCMQYFCWICMG 309
           W+  N+K CP C   IEK  GCN M C    C   FCW+C+G
Sbjct: 336 WIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLG 377


>gi|38045938 ring finger protein 144 [Homo sapiens]
          Length = 292

 Score = 96.3 bits (238), Expect = 4e-20
 Identities = 63/247 (25%), Positives = 105/247 (42%), Gaps = 33/247 (13%)

Query: 91  LFLCSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVA-- 148
           L  C +C  E    +     +C+ ++C  CLK Y E+ I++G    ++CP+  CP     
Sbjct: 17  LVSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETAISCPDAACPKQGHL 76

Query: 149 TPGQVKELVEAELFARYDRLLLQSSLDLMADVVYCPRPCCQ-LPVMQEPGCTMG---ICS 204
              +++ +V AE+  RY +L  +  +       +CP   CQ +  +Q+ G        C 
Sbjct: 77  QENEIECMVAAEIMQRYKKLQFEREVLFDPCRTWCPASTCQAVCQLQDVGLQTPQPVQCK 136

Query: 205 SCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEE 264
           +C   FC+ C+ ++H    C  T      +   +L  + +                A  +
Sbjct: 137 ACRMEFCSTCKASWHPGQGCPET------MPITFLPGETS----------------AAFK 174

Query: 265 MESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMGSLSRANPYKHFNDPG 324
           ME     +   K CP C   IE+ +GC +M C  C   FCW C+ SL       H++   
Sbjct: 175 MEED---DAPIKRCPKCKVYIERDEGCAQMMCKNCKHAFCWYCLESLDDDFLLIHYDK-- 229

Query: 325 SPCFNRL 331
            PC N+L
Sbjct: 230 GPCRNKL 236



 Score = 28.9 bits (63), Expect = 7.1
 Identities = 30/141 (21%), Positives = 51/141 (36%), Gaps = 11/141 (7%)

Query: 179 DVVYCPRPCCQLPVMQEPGCTMGICSSCNFAFCTLCRLTY------HGVSPCKVTAEKLM 232
           D+   P   C+L + + P   M   + C   FCTLC   Y       G+    ++     
Sbjct: 11  DLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETA-ISCPDAA 69

Query: 233 DLRNEYLQADEANKRL---LDQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTPIEKLD 289
             +  +LQ +E    +   + QRY K   ++ +     + W   ++    C    +  L 
Sbjct: 70  CPKQGHLQENEIECMVAAEIMQRYKKLQFEREVLFDPCRTWCPASTCQAVCQLQDV-GLQ 128

Query: 290 GCNKMTCTGCMQYFCWICMGS 310
               + C  C   FC  C  S
Sbjct: 129 TPQPVQCKACRMEFCSTCKAS 149


>gi|148596953 ankyrin repeat and IBR domain containing 1 [Homo
           sapiens]
          Length = 1089

 Score = 93.6 bits (231), Expect = 2e-19
 Identities = 58/234 (24%), Positives = 99/234 (42%), Gaps = 34/234 (14%)

Query: 93  LCSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQ 152
           LC IC C     E    + C H +C+ C + +  ++I++G+   + CP   C  +     
Sbjct: 332 LCDICMCSISVFEDPVDMPCGHDFCRGCWESFLNLKIQEGEAHNIFCPAYDCFQLVPVDI 391

Query: 153 VKELVEAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPV-MQEPGCTMGICSSCNFA-- 209
           ++ +V  E+  RY +  +++ ++    + +CP P C   V + + G       + +F   
Sbjct: 392 IESVVSKEMDKRYLQFDIKAFVENNPAIKWCPTPGCDRAVRLTKQGSNTSGSDTLSFPLL 451

Query: 210 ------------FCTLCRLTYHGVSPC---KVTAEKLMDLRNEYLQADEANKRLLDQRYG 254
                       FC  C    H    C   K   +K+ +++ E L               
Sbjct: 452 RAPAVDCGKGHLFCWECLGEAHEPCDCQTWKNWLQKITEMKPEELVG------------- 498

Query: 255 KRVIQKALEEMESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICM 308
              + +A E+  +  WL  NSK C  C +PI+K +GCN M C  C   FCWIC+
Sbjct: 499 ---VSEAYEDAANCLWLLTNSKPCANCKSPIQKNEGCNHMQCAKCKYDFCWICL 549


>gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo
            sapiens]
          Length = 2517

 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 60/221 (27%), Positives = 95/221 (42%), Gaps = 26/221 (11%)

Query: 94   CSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQV 153
            C +C       + +  L C H  CK+C  +Y   +I    V    CP   CP+  T   +
Sbjct: 2070 CPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFI 2129

Query: 154  KELVEA-ELFARYDRLLLQSSLDLMADVVYC--PRPCCQLPVMQEPGCTMGICSSCNFAF 210
            + +V + E+ ++Y++ LL+  ++  +++ +C  P+ C ++   Q  GC    CS C +A 
Sbjct: 2130 RAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGT-TCSKCGWAS 2188

Query: 211  CTLCRL-TYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKE 269
            C  C     H  + C   ++ + D    Y                         E +SK 
Sbjct: 2189 CFNCSFPEAHYPASCGHMSQWVDD--GGYYDGMSV-------------------EAQSKH 2227

Query: 270  WLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMGS 310
              +  SK CP C  PIEK +GC  MTC  C   FCW C+ S
Sbjct: 2228 LAKLISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKS 2268


>gi|188219579 ring finger protein 19B isoform b [Homo sapiens]
          Length = 587

 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 59/226 (26%), Positives = 91/226 (40%), Gaps = 29/226 (12%)

Query: 94  CSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQV 153
           C +C            L C H  C+ CL+ Y  ++I + +V  ++CPE  C     P  +
Sbjct: 119 CPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVP-ISCPE--CSERLNPHDI 175

Query: 154 KELV-EAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQE--PGCTMGICS--SCNF 208
           + L+ +  L  +Y+  +L+  L    D  +CP P C   V+      C    C    C  
Sbjct: 176 RLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQT 235

Query: 209 AFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESK 268
            FC  C+  +H    C +  ++    R + L+     K      YG+             
Sbjct: 236 EFCYHCKQIWHPNQTCDMARQQ----RAQTLRV--RTKHTSGLSYGQ------------- 276

Query: 269 EWLEKNSKSCPCCGTPIEKLD--GCNKMTCTGCMQYFCWICMGSLS 312
           E    + K CP C   I K++   CN MTC  C   FCW+CM  +S
Sbjct: 277 ESGPDDIKPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEIS 322


>gi|188219577 ring finger protein 19B isoform a [Homo sapiens]
          Length = 732

 Score = 77.8 bits (190), Expect = 1e-14
 Identities = 58/226 (25%), Positives = 91/226 (40%), Gaps = 28/226 (12%)

Query: 94  CSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQV 153
           C +C            L C H  C+ CL+ Y  ++I + +V  ++CPE  C     P  +
Sbjct: 119 CPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVP-ISCPE--CSERLNPHDI 175

Query: 154 KELV-EAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQE--PGCTMGIC--SSCNF 208
           + L+ +  L  +Y+  +L+  L    D  +CP P C   V+      C    C    C  
Sbjct: 176 RLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQT 235

Query: 209 AFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESK 268
            FC  C+  +H    C +  ++    R + L+     K      YG+            +
Sbjct: 236 EFCYHCKQIWHPNQTCDMARQQ----RAQTLRV--RTKHTSGLSYGQ------------E 277

Query: 269 EWLEKNSKSCPCCGTPIEKLD--GCNKMTCTGCMQYFCWICMGSLS 312
                + K CP C   I K++   CN MTC  C   FCW+CM  +S
Sbjct: 278 SGPADDIKPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEIS 323


>gi|169790973 parkin isoform 3 [Homo sapiens]
          Length = 316

 Score = 76.6 bits (187), Expect = 3e-14
 Identities = 68/251 (27%), Positives = 98/251 (39%), Gaps = 34/251 (13%)

Query: 88  NSKLFLCSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEP----K 143
           NS+   C  C  +      ++    RHV C  C   Y   ++ D Q   ++ P+      
Sbjct: 83  NSRNITCITC-TDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQF--VHDPQLGYSLP 139

Query: 144 CPSVATPGQVKEL-----VEAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQEPG- 197
           C +      +KEL     +  E + RY +   +  +  M  V+ CPRP C   ++ EP  
Sbjct: 140 CVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVL-CPRPGCGAGLLPEPDQ 198

Query: 198 ----CTMGICSSCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRY 253
               C  G    C FAFC  C+  YH    C    E        Y             R 
Sbjct: 199 RKVTCEGGNGLGCGFAFCRECKEAYHE-GECSAVFEASGTTTQAY-------------RV 244

Query: 254 GKRVIQKALEEMESKEWLEKNSKSCPCCGTPIEKLDGCNKMTC--TGCMQYFCWICMGSL 311
            +R  ++A  E  SKE ++K +K CP C  P+EK  GC  M C    C   +CW C    
Sbjct: 245 DERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEW 304

Query: 312 SRANPYKHFND 322
           +R     H+ D
Sbjct: 305 NRVCMGDHWFD 315


>gi|169790971 parkin isoform 2 [Homo sapiens]
          Length = 437

 Score = 76.6 bits (187), Expect = 3e-14
 Identities = 68/251 (27%), Positives = 98/251 (39%), Gaps = 34/251 (13%)

Query: 88  NSKLFLCSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEP----K 143
           NS+   C  C  +      ++    RHV C  C   Y   ++ D Q   ++ P+      
Sbjct: 204 NSRNITCITC-TDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQF--VHDPQLGYSLP 260

Query: 144 CPSVATPGQVKEL-----VEAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQEPG- 197
           C +      +KEL     +  E + RY +   +  +  M  V+ CPRP C   ++ EP  
Sbjct: 261 CVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVL-CPRPGCGAGLLPEPDQ 319

Query: 198 ----CTMGICSSCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRY 253
               C  G    C FAFC  C+  YH    C    E        Y             R 
Sbjct: 320 RKVTCEGGNGLGCGFAFCRECKEAYHE-GECSAVFEASGTTTQAY-------------RV 365

Query: 254 GKRVIQKALEEMESKEWLEKNSKSCPCCGTPIEKLDGCNKMTC--TGCMQYFCWICMGSL 311
            +R  ++A  E  SKE ++K +K CP C  P+EK  GC  M C    C   +CW C    
Sbjct: 366 DERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEW 425

Query: 312 SRANPYKHFND 322
           +R     H+ D
Sbjct: 426 NRVCMGDHWFD 436


>gi|169790969 parkin isoform 1 [Homo sapiens]
          Length = 465

 Score = 76.6 bits (187), Expect = 3e-14
 Identities = 68/251 (27%), Positives = 98/251 (39%), Gaps = 34/251 (13%)

Query: 88  NSKLFLCSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEP----K 143
           NS+   C  C  +      ++    RHV C  C   Y   ++ D Q   ++ P+      
Sbjct: 232 NSRNITCITC-TDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQF--VHDPQLGYSLP 288

Query: 144 CPSVATPGQVKEL-----VEAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQEPG- 197
           C +      +KEL     +  E + RY +   +  +  M  V+ CPRP C   ++ EP  
Sbjct: 289 CVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVL-CPRPGCGAGLLPEPDQ 347

Query: 198 ----CTMGICSSCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRY 253
               C  G    C FAFC  C+  YH    C    E        Y             R 
Sbjct: 348 RKVTCEGGNGLGCGFAFCRECKEAYHE-GECSAVFEASGTTTQAY-------------RV 393

Query: 254 GKRVIQKALEEMESKEWLEKNSKSCPCCGTPIEKLDGCNKMTC--TGCMQYFCWICMGSL 311
            +R  ++A  E  SKE ++K +K CP C  P+EK  GC  M C    C   +CW C    
Sbjct: 394 DERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEW 453

Query: 312 SRANPYKHFND 322
           +R     H+ D
Sbjct: 454 NRVCMGDHWFD 464


>gi|35493801 ring finger protein 19 [Homo sapiens]
          Length = 838

 Score = 76.3 bits (186), Expect = 4e-14
 Identities = 54/226 (23%), Positives = 86/226 (38%), Gaps = 27/226 (11%)

Query: 94  CSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQV 153
           C +C            + C H  C  CL+ Y  I+I + +V  ++CPE  C     P  +
Sbjct: 132 CPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVN-ISCPE--CTERFNPHDI 188

Query: 154 KELVEAE-LFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQE--PGCTMGICS--SCNF 208
           + ++  + L  +Y+  +L+  L    D  +CP P C   V+      C    C    C  
Sbjct: 189 RLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCGT 248

Query: 209 AFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESK 268
            FC  C+  +H    C                 D A +        + +   ++   +  
Sbjct: 249 EFCYHCKQIWHPNQTC-----------------DAARQERAQSLRLRTIRSSSISYSQES 291

Query: 269 EWLEKNSKSCPCCGTPIEKLD--GCNKMTCTGCMQYFCWICMGSLS 312
                + K CP C   I K++   CN MTC  C   FCW+CM  +S
Sbjct: 292 GAAADDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEIS 337


>gi|35493782 ring finger protein 19 [Homo sapiens]
          Length = 838

 Score = 76.3 bits (186), Expect = 4e-14
 Identities = 54/226 (23%), Positives = 86/226 (38%), Gaps = 27/226 (11%)

Query: 94  CSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQV 153
           C +C            + C H  C  CL+ Y  I+I + +V  ++CPE  C     P  +
Sbjct: 132 CPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVN-ISCPE--CTERFNPHDI 188

Query: 154 KELVEAE-LFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQE--PGCTMGICS--SCNF 208
           + ++  + L  +Y+  +L+  L    D  +CP P C   V+      C    C    C  
Sbjct: 189 RLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCGT 248

Query: 209 AFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESK 268
            FC  C+  +H    C                 D A +        + +   ++   +  
Sbjct: 249 EFCYHCKQIWHPNQTC-----------------DAARQERAQSLRLRTIRSSSISYSQES 291

Query: 269 EWLEKNSKSCPCCGTPIEKLD--GCNKMTCTGCMQYFCWICMGSLS 312
                + K CP C   I K++   CN MTC  C   FCW+CM  +S
Sbjct: 292 GAAADDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEIS 337


>gi|5454168 RanBP-type and C3HC4-type zinc finger containing 1
           isoform 1 [Homo sapiens]
          Length = 468

 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 56/232 (24%), Positives = 96/232 (41%), Gaps = 27/232 (11%)

Query: 82  QQIKCFNSKLFLCSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCP- 140
           Q+    N++   C +C+      E +   EC H +C+ CL+      IR+ Q   ++CP 
Sbjct: 228 QRSLVLNTEPAECPVCYSVLAPGEAVVLRECLHTFCRECLQG----TIRNSQEAEVSCPF 283

Query: 141 ---EPKCPSVATPGQVKELVEAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQEPG 197
                 C       ++K L+  E + R+  L +  + +  A   +C  P C+     E  
Sbjct: 284 IDNTYSCSGKLLEREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFEDD 343

Query: 198 CTMGICSSCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRV 257
                C  C    C LC+  +  ++ CK   E L  LR    Q D A ++  +      +
Sbjct: 344 VNEFTCPVCFHVNCLLCKAIHEQMN-CKEYQEDLA-LR---AQNDVAARQTTE------M 392

Query: 258 IQKALEEMESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMG 309
           ++  L++ E+          CP C   ++K DGC+ + CT C    CW+  G
Sbjct: 393 LKVMLQQGEAMR--------CPQCQIVVQKKDGCDWIRCTVCHTEICWVTKG 436


>gi|144953898 RanBP-type and C3HC4-type zinc finger containing 1
           isoform 2 [Homo sapiens]
          Length = 510

 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 56/232 (24%), Positives = 96/232 (41%), Gaps = 27/232 (11%)

Query: 82  QQIKCFNSKLFLCSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCP- 140
           Q+    N++   C +C+      E +   EC H +C+ CL+      IR+ Q   ++CP 
Sbjct: 270 QRSLVLNTEPAECPVCYSVLAPGEAVVLRECLHTFCRECLQG----TIRNSQEAEVSCPF 325

Query: 141 ---EPKCPSVATPGQVKELVEAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQEPG 197
                 C       ++K L+  E + R+  L +  + +  A   +C  P C+     E  
Sbjct: 326 IDNTYSCSGKLLEREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFEDD 385

Query: 198 CTMGICSSCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRV 257
                C  C    C LC+  +  ++ CK   E L  LR    Q D A ++  +      +
Sbjct: 386 VNEFTCPVCFHVNCLLCKAIHEQMN-CKEYQEDLA-LR---AQNDVAARQTTE------M 434

Query: 258 IQKALEEMESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMG 309
           ++  L++ E+          CP C   ++K DGC+ + CT C    CW+  G
Sbjct: 435 LKVMLQQGEAMR--------CPQCQIVVQKKDGCDWIRCTVCHTEICWVTKG 478


>gi|46370057 ring finger protein 216 isoform b [Homo sapiens]
          Length = 866

 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 72/287 (25%), Positives = 115/287 (40%), Gaps = 47/287 (16%)

Query: 51  VDQEEIVDERAVQDVESLSNLIQEILDFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFL 110
           V QE+   E+ ++++    + +   L  ++ Q  K  + +L  C  C+ E    E     
Sbjct: 475 VQQEQEFYEQKIKEMAEHEDFLLA-LQMNEEQYQK--DGQLIECRCCYGEFPFEELTQCA 531

Query: 111 ECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCP-SVATPGQVKELVEAELFARYDRLL 169
           +  H++CK CL  Y +  +       L+C E  C  S  T    K L +  L+  Y+R  
Sbjct: 532 DA-HLFCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKA 590

Query: 170 LQSSLDLMAD-VVYCPRPCCQLPVMQEPGCTMGICSS--CNFAFCTLCRLTY--HGVSPC 224
            +      AD +V CP   C  P + +       C +  C    C  C+  +  H    C
Sbjct: 591 EEEVAAAYADELVRCPS--CSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTC 648

Query: 225 KVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTP 284
           +  AEK           D+   R             ++EE  +   + K    C  CGT 
Sbjct: 649 EELAEK-----------DDIKYRT------------SIEEKMTAARIRK----CHKCGTG 681

Query: 285 IEKLDGCNKMTCTGCMQYFCWICMGSLSRANPYKHF----NDPGSPC 327
           + K +GCN+M+C  C    C++C  S+   N Y HF      PG+PC
Sbjct: 682 LIKSEGCNRMSCR-CGAQMCYLCRVSI---NGYDHFCQHPRSPGAPC 724


>gi|46358403 ring finger protein 216 isoform a [Homo sapiens]
          Length = 923

 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 72/287 (25%), Positives = 115/287 (40%), Gaps = 47/287 (16%)

Query: 51  VDQEEIVDERAVQDVESLSNLIQEILDFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFL 110
           V QE+   E+ ++++    + +   L  ++ Q  K  + +L  C  C+ E    E     
Sbjct: 532 VQQEQEFYEQKIKEMAEHEDFLLA-LQMNEEQYQK--DGQLIECRCCYGEFPFEELTQCA 588

Query: 111 ECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCP-SVATPGQVKELVEAELFARYDRLL 169
           +  H++CK CL  Y +  +       L+C E  C  S  T    K L +  L+  Y+R  
Sbjct: 589 DA-HLFCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKA 647

Query: 170 LQSSLDLMAD-VVYCPRPCCQLPVMQEPGCTMGICSS--CNFAFCTLCRLTY--HGVSPC 224
            +      AD +V CP   C  P + +       C +  C    C  C+  +  H    C
Sbjct: 648 EEEVAAAYADELVRCPS--CSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTC 705

Query: 225 KVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTP 284
           +  AEK           D+   R             ++EE  +   + K    C  CGT 
Sbjct: 706 EELAEK-----------DDIKYRT------------SIEEKMTAARIRK----CHKCGTG 738

Query: 285 IEKLDGCNKMTCTGCMQYFCWICMGSLSRANPYKHF----NDPGSPC 327
           + K +GCN+M+C  C    C++C  S+   N Y HF      PG+PC
Sbjct: 739 LIKSEGCNRMSCR-CGAQMCYLCRVSI---NGYDHFCQHPRSPGAPC 781


>gi|22749145 ring finger protein 217 [Homo sapiens]
          Length = 275

 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 25/105 (23%), Positives = 45/105 (42%), Gaps = 27/105 (25%)

Query: 203 CSSCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKAL 262
           C +C F +C  C   +H    CK                        + + G ++++   
Sbjct: 83  CPTCQFVWCFKCHSPWHEGVNCK------------------------EYKKGDKLLRHWA 118

Query: 263 EEMESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWIC 307
            E+E  +   +N++ CP C   I++ +GC+ MTC+ C   FC+ C
Sbjct: 119 SEIEHGQ---RNAQKCPKCKIHIQRTEGCDHMTCSQCNTNFCYRC 160



 Score = 35.4 bits (80), Expect = 0.076
 Identities = 23/89 (25%), Positives = 39/89 (43%), Gaps = 7/89 (7%)

Query: 133 QVQCLNCPEPKCPSVATPGQVKELVEAELFARYDRLLLQSSLDL---MADVVYCPRPCCQ 189
           ++QC  C    C    +P    E V  + + + D+LL   + ++     +   CP+  C+
Sbjct: 80  KIQCPTCQFVWCFKCHSPWH--EGVNCKEYKKGDKLLRHWASEIEHGQRNAQKCPK--CK 135

Query: 190 LPVMQEPGCTMGICSSCNFAFCTLCRLTY 218
           + + +  GC    CS CN  FC  C   Y
Sbjct: 136 IHIQRTEGCDHMTCSQCNTNFCYRCGERY 164


>gi|109150431 ring finger protein 31 [Homo sapiens]
          Length = 1072

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 46/237 (19%), Positives = 81/237 (34%), Gaps = 41/237 (17%)

Query: 94  CSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPG-- 151
           C++C      +       C    C  C + +F I +++  +  + CP    P +      
Sbjct: 699 CAVCGWALPHNRMQALTSCECTICPDCFRQHFTIALKEKHITDMVCPACGRPDLTDDTQL 758

Query: 152 ---------QVKELVEAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQEPGCTMGI 202
                    Q++E +E + +A + + L +  L      ++C +  C    + E       
Sbjct: 759 LSYFSTLDIQLRESLEPDAYALFHKKLTEGVLMRDPKFLWCAQ--CSFGFIYEREQLEAT 816

Query: 203 CSSCNFAFCTLCRLTY---HGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQ 259
           C  C+  FC  C+  +   H    C+       D +N         KR+ D  Y  + + 
Sbjct: 817 CPQCHQTFCVRCKRQWEEQHRGRSCE-------DFQNW--------KRMNDPEYQAQGLA 861

Query: 260 KALEEMESKEWLEKNSKSCPCCGTPIE-KLDGCNKMTCTGCMQYFCWICMGSLSRAN 315
                     +L++N   CP C         GC    CT C   FC  C  +    N
Sbjct: 862 M---------YLQENGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKN 909


>gi|117606347 F-box protein 43 isoform a [Homo sapiens]
          Length = 674

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 28/76 (36%), Positives = 34/76 (44%), Gaps = 3/76 (3%)

Query: 176 LMADVVYCPRPCCQLPVMQEPGCTMGICS--SCNFAFCTLCRLTYHGVSPCKVTAEKLMD 233
           L  D    P P CQ P   +P    G+CS  +C F FC LC   YHG   C   A K  +
Sbjct: 597 LFTDEALKPCPRCQSPAKYQPYKKRGLCSRTACGFDFCVLCLCAYHGSEECSRGAAKPRN 656

Query: 234 LRNEYLQADEANKRLL 249
            R + L     +KR L
Sbjct: 657 -RKDALPGSAQSKRNL 671


>gi|117606351 F-box protein 43 isoform b [Homo sapiens]
          Length = 708

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 28/76 (36%), Positives = 34/76 (44%), Gaps = 3/76 (3%)

Query: 176 LMADVVYCPRPCCQLPVMQEPGCTMGICS--SCNFAFCTLCRLTYHGVSPCKVTAEKLMD 233
           L  D    P P CQ P   +P    G+CS  +C F FC LC   YHG   C   A K  +
Sbjct: 631 LFTDEALKPCPRCQSPAKYQPYKKRGLCSRTACGFDFCVLCLCAYHGSEECSRGAAKPRN 690

Query: 234 LRNEYLQADEANKRLL 249
            R + L     +KR L
Sbjct: 691 -RKDALPGSAQSKRNL 705


>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
           sapiens]
          Length = 4911

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 37/147 (25%), Positives = 55/147 (37%), Gaps = 22/147 (14%)

Query: 183 CPRPCCQLPVMQEPGCTMGICSS----CNFAFCTLCRLTYHG------VSPCKVTAEKLM 232
           CP    Q P   +      +C S     +  FCT C   YHG      V+P K    +  
Sbjct: 327 CPEHIDQAPERSKEDANCAVCDSPGDLLDQFFCTTCGQHYHGMCLDIAVTPLKRAGWQCP 386

Query: 233 DLR--NEYLQADEANKRLL----DQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTPIE 286
           + +      Q+ E +K L+    D+ Y    +Q  ++ + +  W  KN + C  CGT   
Sbjct: 387 ECKVCQNCKQSGEDSKMLVCDTCDKGYHTFCLQPVMKSVPTNGWKCKNCRICIECGTRSS 446

Query: 287 KLDGCNKMTCTGCMQY------FCWIC 307
                N + C  C Q       FC  C
Sbjct: 447 SQWHHNCLICDNCYQQQDNLCPFCGKC 473


>gi|32454739 tripartite motif-containing 3 [Homo sapiens]
          Length = 744

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 37/145 (25%), Positives = 56/145 (38%), Gaps = 20/145 (13%)

Query: 83  QIKCFNSKLFLCSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEP 142
           +++  + +  +CSIC       +C   L C H +C+ CL++Y        Q   L+CP  
Sbjct: 11  EVQPMDKQFLVCSICLDRY---QCPKVLPCLHTFCERCLQNYI-----PAQSLTLSCPVC 62

Query: 143 KCPSVATPGQVKELVEAELFARYDRLLLQSSLDLMAD-------VVYCPRPCCQLPVMQE 195
           +  S+  P Q    ++   F       +Q + D   D        V   RP   L     
Sbjct: 63  RQTSI-LPEQGVSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLSVVAGRP---LSCPNH 118

Query: 196 PGCTMGI-CSSCNFAFCTLCRLTYH 219
            G TM   C +C  A C  CR   H
Sbjct: 119 EGKTMEFYCEACETAMCGECRAGEH 143


>gi|32454737 tripartite motif-containing 3 [Homo sapiens]
          Length = 744

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 37/145 (25%), Positives = 56/145 (38%), Gaps = 20/145 (13%)

Query: 83  QIKCFNSKLFLCSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEP 142
           +++  + +  +CSIC       +C   L C H +C+ CL++Y        Q   L+CP  
Sbjct: 11  EVQPMDKQFLVCSICLDRY---QCPKVLPCLHTFCERCLQNYI-----PAQSLTLSCPVC 62

Query: 143 KCPSVATPGQVKELVEAELFARYDRLLLQSSLDLMAD-------VVYCPRPCCQLPVMQE 195
           +  S+  P Q    ++   F       +Q + D   D        V   RP   L     
Sbjct: 63  RQTSI-LPEQGVSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLSVVAGRP---LSCPNH 118

Query: 196 PGCTMGI-CSSCNFAFCTLCRLTYH 219
            G TM   C +C  A C  CR   H
Sbjct: 119 EGKTMEFYCEACETAMCGECRAGEH 143


>gi|56605981 tripartite motif-containing 72 [Homo sapiens]
          Length = 477

 Score = 35.4 bits (80), Expect = 0.076
 Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 14/96 (14%)

Query: 111 ECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCP-SVATPGQVKELVEAELFARYDRLL 169
           EC H +C+ACL         DG V C  C  P  P +++T  Q+  LVE    A+  +  
Sbjct: 28  ECGHSFCRACLGRVAGEPAADGTVLCPCCQAPTRPQALSTNLQLARLVEG--LAQVPQGH 85

Query: 170 LQSSLDLMADVVYCPRPCCQLPVMQEPGCTMGICSS 205
            +  LD ++  +YC          Q+     G+C+S
Sbjct: 86  CEEHLDPLS--IYCE---------QDRALVCGVCAS 110


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.137    0.441 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,388,553
Number of Sequences: 37866
Number of extensions: 666689
Number of successful extensions: 2870
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 44
Number of HSP's successfully gapped in prelim test: 69
Number of HSP's that attempted gapping in prelim test: 2676
Number of HSP's gapped (non-prelim): 207
length of query: 348
length of database: 18,247,518
effective HSP length: 103
effective length of query: 245
effective length of database: 14,347,320
effective search space: 3515093400
effective search space used: 3515093400
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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