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Search of human proteins with 33457330
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|33457330 tetratricopeptide repeat domain 14 isoform a [Homo
sapiens]
(770 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|33457330 tetratricopeptide repeat domain 14 isoform a [Homo s... 1531 0.0
gi|110611917 tetratricopeptide repeat domain 14 isoform b [Homo ... 856 0.0
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 63 1e-09
gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens] 62 2e-09
gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens] 62 2e-09
gi|52426743 cisplatin resistance-associated overexpressed protei... 61 3e-09
gi|19923485 cisplatin resistance-associated overexpressed protei... 61 3e-09
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 60 8e-09
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 60 8e-09
gi|27734775 hypothetical protein LOC286499 [Homo sapiens] 59 1e-08
gi|40068059 CBF1 interacting corepressor [Homo sapiens] 59 2e-08
gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi... 59 2e-08
gi|148746195 trichohyalin [Homo sapiens] 57 5e-08
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 55 2e-07
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 55 2e-07
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 55 2e-07
gi|34878904 synaptonemal complex protein 1 [Homo sapiens] 55 2e-07
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 55 3e-07
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 54 4e-07
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 54 5e-07
gi|33356174 pinin, desmosome associated protein [Homo sapiens] 54 5e-07
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 54 5e-07
gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 53 9e-07
gi|50962882 G patch domain containing 8 [Homo sapiens] 53 9e-07
gi|8923106 zinc finger, CCHC domain containing 10 [Homo sapiens] 53 9e-07
gi|31982906 cingulin-like 1 [Homo sapiens] 52 2e-06
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 52 2e-06
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 52 2e-06
gi|118766347 zinc finger CCCH-type domain containing 6 [Homo sap... 52 3e-06
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 51 4e-06
>gi|33457330 tetratricopeptide repeat domain 14 isoform a [Homo
sapiens]
Length = 770
Score = 1531 bits (3965), Expect = 0.0
Identities = 770/770 (100%), Positives = 770/770 (100%)
Query: 1 MDRDLLRQSLNCHGSSLLSLLRSEQQDNPHFRSLLGSAAEPARGPPPQHPLQGRKEKRVD 60
MDRDLLRQSLNCHGSSLLSLLRSEQQDNPHFRSLLGSAAEPARGPPPQHPLQGRKEKRVD
Sbjct: 1 MDRDLLRQSLNCHGSSLLSLLRSEQQDNPHFRSLLGSAAEPARGPPPQHPLQGRKEKRVD 60
Query: 61 NIEIQKFISKKADLLFALSWKSDAPATSEINEDSEDHYAIMPPLEQFMEIPSMDRRELFF 120
NIEIQKFISKKADLLFALSWKSDAPATSEINEDSEDHYAIMPPLEQFMEIPSMDRRELFF
Sbjct: 61 NIEIQKFISKKADLLFALSWKSDAPATSEINEDSEDHYAIMPPLEQFMEIPSMDRRELFF 120
Query: 121 RDIERGDIVIGRISSIREFGFFMVLICLGSGIMRDIAHLEITALCPLRDVPSHSNHGDPL 180
RDIERGDIVIGRISSIREFGFFMVLICLGSGIMRDIAHLEITALCPLRDVPSHSNHGDPL
Sbjct: 121 RDIERGDIVIGRISSIREFGFFMVLICLGSGIMRDIAHLEITALCPLRDVPSHSNHGDPL 180
Query: 181 SYYQTGDIIRAGIKDIDRYHEKLAVSLYSSSLPPHLSGIKLGVISSEELPLYYRRSVELN 240
SYYQTGDIIRAGIKDIDRYHEKLAVSLYSSSLPPHLSGIKLGVISSEELPLYYRRSVELN
Sbjct: 181 SYYQTGDIIRAGIKDIDRYHEKLAVSLYSSSLPPHLSGIKLGVISSEELPLYYRRSVELN 240
Query: 241 SNSLESYENVMQSSLGFVNPGVVEFLLEKLGIDESNPPSLMRGLQSKNFSEDDFASALRK 300
SNSLESYENVMQSSLGFVNPGVVEFLLEKLGIDESNPPSLMRGLQSKNFSEDDFASALRK
Sbjct: 241 SNSLESYENVMQSSLGFVNPGVVEFLLEKLGIDESNPPSLMRGLQSKNFSEDDFASALRK 300
Query: 301 KQSASWALKCVKIGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKA 360
KQSASWALKCVKIGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKA
Sbjct: 301 KQSASWALKCVKIGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKA 360
Query: 361 IEDFELALENCPTHRNARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALDETFKDAED 420
IEDFELALENCPTHRNARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALDETFKDAED
Sbjct: 361 IEDFELALENCPTHRNARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALDETFKDAED 420
Query: 421 ALQKLHKYMQKSLELREKQAEKEEKQKTKKIETSAEKLRKLLKEEKRLKKKRRKSTSSSS 480
ALQKLHKYMQKSLELREKQAEKEEKQKTKKIETSAEKLRKLLKEEKRLKKKRRKSTSSSS
Sbjct: 421 ALQKLHKYMQKSLELREKQAEKEEKQKTKKIETSAEKLRKLLKEEKRLKKKRRKSTSSSS 480
Query: 481 VSSADESVSSSSSSSSSGHKRHKKHKRNRSESSRSSRRHSSRASSNQIDQNRKDECYPVP 540
VSSADESVSSSSSSSSSGHKRHKKHKRNRSESSRSSRRHSSRASSNQIDQNRKDECYPVP
Sbjct: 481 VSSADESVSSSSSSSSSGHKRHKKHKRNRSESSRSSRRHSSRASSNQIDQNRKDECYPVP 540
Query: 541 ANTSASFLNHKQEVEKLLGKQDRLQYEKTQIKEKDRCPLSSSSLEIPDDFGGRSEDPRDF 600
ANTSASFLNHKQEVEKLLGKQDRLQYEKTQIKEKDRCPLSSSSLEIPDDFGGRSEDPRDF
Sbjct: 541 ANTSASFLNHKQEVEKLLGKQDRLQYEKTQIKEKDRCPLSSSSLEIPDDFGGRSEDPRDF 600
Query: 601 YNSYKTQAGSSKTEKPYKSERHFSSRRNSSDSFCRNSEDKIYGYRRFEKDIEGRKEHYRR 660
YNSYKTQAGSSKTEKPYKSERHFSSRRNSSDSFCRNSEDKIYGYRRFEKDIEGRKEHYRR
Sbjct: 601 YNSYKTQAGSSKTEKPYKSERHFSSRRNSSDSFCRNSEDKIYGYRRFEKDIEGRKEHYRR 660
Query: 661 WEPGSVRHSTSPASSEYSWKSVEKYKKYAHSGSRDFSRHEQRYRLNTNQGEYEREDNYGE 720
WEPGSVRHSTSPASSEYSWKSVEKYKKYAHSGSRDFSRHEQRYRLNTNQGEYEREDNYGE
Sbjct: 661 WEPGSVRHSTSPASSEYSWKSVEKYKKYAHSGSRDFSRHEQRYRLNTNQGEYEREDNYGE 720
Query: 721 DIKTEVPEEDALSSKEHSESSVKKNLPQNLLNIFNQIAEFEKEKGNKSKN 770
DIKTEVPEEDALSSKEHSESSVKKNLPQNLLNIFNQIAEFEKEKGNKSKN
Sbjct: 721 DIKTEVPEEDALSSKEHSESSVKKNLPQNLLNIFNQIAEFEKEKGNKSKN 770
>gi|110611917 tetratricopeptide repeat domain 14 isoform b [Homo
sapiens]
Length = 439
Score = 856 bits (2212), Expect = 0.0
Identities = 430/430 (100%), Positives = 430/430 (100%)
Query: 1 MDRDLLRQSLNCHGSSLLSLLRSEQQDNPHFRSLLGSAAEPARGPPPQHPLQGRKEKRVD 60
MDRDLLRQSLNCHGSSLLSLLRSEQQDNPHFRSLLGSAAEPARGPPPQHPLQGRKEKRVD
Sbjct: 1 MDRDLLRQSLNCHGSSLLSLLRSEQQDNPHFRSLLGSAAEPARGPPPQHPLQGRKEKRVD 60
Query: 61 NIEIQKFISKKADLLFALSWKSDAPATSEINEDSEDHYAIMPPLEQFMEIPSMDRRELFF 120
NIEIQKFISKKADLLFALSWKSDAPATSEINEDSEDHYAIMPPLEQFMEIPSMDRRELFF
Sbjct: 61 NIEIQKFISKKADLLFALSWKSDAPATSEINEDSEDHYAIMPPLEQFMEIPSMDRRELFF 120
Query: 121 RDIERGDIVIGRISSIREFGFFMVLICLGSGIMRDIAHLEITALCPLRDVPSHSNHGDPL 180
RDIERGDIVIGRISSIREFGFFMVLICLGSGIMRDIAHLEITALCPLRDVPSHSNHGDPL
Sbjct: 121 RDIERGDIVIGRISSIREFGFFMVLICLGSGIMRDIAHLEITALCPLRDVPSHSNHGDPL 180
Query: 181 SYYQTGDIIRAGIKDIDRYHEKLAVSLYSSSLPPHLSGIKLGVISSEELPLYYRRSVELN 240
SYYQTGDIIRAGIKDIDRYHEKLAVSLYSSSLPPHLSGIKLGVISSEELPLYYRRSVELN
Sbjct: 181 SYYQTGDIIRAGIKDIDRYHEKLAVSLYSSSLPPHLSGIKLGVISSEELPLYYRRSVELN 240
Query: 241 SNSLESYENVMQSSLGFVNPGVVEFLLEKLGIDESNPPSLMRGLQSKNFSEDDFASALRK 300
SNSLESYENVMQSSLGFVNPGVVEFLLEKLGIDESNPPSLMRGLQSKNFSEDDFASALRK
Sbjct: 241 SNSLESYENVMQSSLGFVNPGVVEFLLEKLGIDESNPPSLMRGLQSKNFSEDDFASALRK 300
Query: 301 KQSASWALKCVKIGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKA 360
KQSASWALKCVKIGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKA
Sbjct: 301 KQSASWALKCVKIGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKA 360
Query: 361 IEDFELALENCPTHRNARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALDETFKDAED 420
IEDFELALENCPTHRNARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALDETFKDAED
Sbjct: 361 IEDFELALENCPTHRNARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALDETFKDAED 420
Query: 421 ALQKLHKYMQ 430
ALQKLHKYMQ
Sbjct: 421 ALQKLHKYMQ 430
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 62.8 bits (151), Expect = 1e-09
Identities = 84/351 (23%), Positives = 134/351 (38%), Gaps = 39/351 (11%)
Query: 423 QKLHKYMQKSLELREKQAEKEEK-----------------QKTKKIETSAEKLRKLLKEE 465
Q L YM+++ E+ A K K +K E + K+R L++++
Sbjct: 118 QDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIR-LVEDK 176
Query: 466 KRLKKKRRKSTSSSSVSSADESVSSSSSSSSSGHKRHKKHKRNRSESSRSSRRHSSRASS 525
+++R S S S S S S S S SG + H ++RS S SR S S
Sbjct: 177 PGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSK-SSHSKSRSRSRSGSRSRSKSRSR 235
Query: 526 NQIDQNRKDECYPVPANTSASFLNHKQEVEKLLGK---QDRLQYEKTQIKEKDRCPLSSS 582
+Q K E P+ + +H + K ++++Q K K R P
Sbjct: 236 SQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHK 295
Query: 583 SLEIPDDFGGRSEDPRDFYNSYKTQAGSSKTEKPYKSERHFSSRRNSSDSFCRN---SED 639
S RS++ R + + EK + R S + S S R+ S+D
Sbjct: 296 S---KSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKD 352
Query: 640 KIYGYRRFEKDIEGRKEHYRRWEPGSVRHS--TSPASSEYSWKSVEKYKKYAHSGSRDFS 697
K G +R ++ R + E R S S A S K + + + S SR S
Sbjct: 353 KRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVS 412
Query: 698 RHEQRYRLNTNQGEYERE-DNYGEDIKTEVPEEDALSSKEHSESSVKKNLP 747
+ + + ++Q E E +N G + +T S+ S S K NLP
Sbjct: 413 KEREHAKSESSQREGRGESENAGTNQETR--------SRSRSNSKSKPNLP 455
Score = 48.9 bits (115), Expect = 2e-05
Identities = 56/270 (20%), Positives = 96/270 (35%), Gaps = 12/270 (4%)
Query: 438 KQAEKEEKQKTKKIETSAEKLRKLLKEEKRLKKKRRKSTSSSSVSSADESVSSSSSSSSS 497
+ K + + + EK R KE+ R + + S S A+E + ++ +
Sbjct: 227 RSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKP 286
Query: 498 GHKRHKKHKRNRSESSRSSRRHSSRASSNQIDQNRKDECYPVPANTSASFLNHKQEVEKL 557
+ +HK SRS R + + R E + + + + +
Sbjct: 287 KSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRS 346
Query: 558 LGKQDRLQYEKTQIKEKDRCPLSSSSLEIPDDFGGRSEDPRDFYNSYKTQAGSSKTEKPY 617
K + + + +E+ R S S +SE R + ++AGSSK +K
Sbjct: 347 RSKSKDKRKGRKRSREESRSRSRSRS---------KSERSRKRGSKRDSKAGSSKKKKKE 397
Query: 618 KSERHFS---SRRNSSDSFCRNSEDKIYGYRRFEKDIEGRKEHYRRWEPGSVRHSTSPAS 674
++R S SR S + SE R ++ +E R S P+
Sbjct: 398 DTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSE 457
Query: 675 SEYSWKSVEKYKKYAHSGSRDFSRHEQRYR 704
S KS K + + S SR SR R R
Sbjct: 458 SRSRSKSASKTRSRSKSRSRSASRSPSRSR 487
Score = 35.8 bits (81), Expect = 0.15
Identities = 31/148 (20%), Positives = 55/148 (37%), Gaps = 10/148 (6%)
Query: 436 REKQAEKEEKQKTKKIETSAEKLRKLLKEEKRLKKKRRKSTSSSSVSSADESVSSSSSSS 495
+EK + + K + + + ++KR +KR + S S S +S S S
Sbjct: 323 QEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGS 382
Query: 496 SSGHKRHKKHKRNRSESSRSSRRHSSRASSNQIDQNRKDECYPVPANTSASFLNHKQEVE 555
K K+ + ++ RS R SR+ S + + A + +S + E E
Sbjct: 383 KRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREH----------AKSESSQREGRGESE 432
Query: 556 KLLGKQDRLQYEKTQIKEKDRCPLSSSS 583
Q+ ++ K K P S S
Sbjct: 433 NAGTNQETRSRSRSNSKSKPNLPSESRS 460
>gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]
Length = 237
Score = 62.4 bits (150), Expect = 2e-09
Identities = 56/223 (25%), Positives = 102/223 (45%), Gaps = 25/223 (11%)
Query: 414 TFKDAEDALQKLHKYMQKSLELREKQAEKEEKQKTKKIETSAEKLRKLLKEEKRLKKKRR 473
T+++ ++ L+K K + E EK E +K+ K E K+ +R KK+++
Sbjct: 30 TWEEVKEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKK 89
Query: 474 KS-TSSSSVSSADESVSSSSSSSSSGHKRHKKHKRNRSESSRSSRRHSSRASSNQIDQNR 532
KS SSS SS+ +S SSSS S K+ K+ K+ ++ S +SS S S+ D +
Sbjct: 90 KSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLK 149
Query: 533 KDECYPVPANTSASFLNHKQEVEKLLGKQDRLQYEKTQIKEKDRCPLSSSSL---EIPDD 589
K + S +++++ L K+ +K PLSS SL E ++
Sbjct: 150 KKK-------KSKDGTEKEKDIKGLSKKRKMYSEDK---------PLSSESLSESEYIEE 193
Query: 590 FGGRSEDPRDFYNSYKTQAGSSKTEKPYKSERHFSSRRNSSDS 632
+ + +S + + + KT+K K ++H ++ + S
Sbjct: 194 VRAKKKK-----SSEEREKATEKTKKKKKHKKHSKKKKKKAAS 231
Score = 39.3 bits (90), Expect = 0.014
Identities = 29/128 (22%), Positives = 56/128 (43%), Gaps = 14/128 (10%)
Query: 393 EEEEKFLNAESYYKKALALDETFKDAEDALQKLHKYMQKSLELREKQAEKEEKQKTKKIE 452
E+E+K KK + + K +E ++ + + SL+ ++K + EK+K K
Sbjct: 112 EDEDKKQGKRRKKKK----NRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKDIK-- 165
Query: 453 TSAEKLRKLLKEEKRLKKKRRKST-------SSSSVSSADESVSSSSSSSSSGHKRHKKH 505
K RK+ E+K L + + + SS + ++ + HK+H K
Sbjct: 166 -GLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEEREKATEKTKKKKKHKKHSKK 224
Query: 506 KRNRSESS 513
K+ ++ SS
Sbjct: 225 KKKKAASS 232
Score = 37.0 bits (84), Expect = 0.069
Identities = 25/107 (23%), Positives = 55/107 (51%), Gaps = 2/107 (1%)
Query: 373 THRNARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALDETFKDAEDALQKLHKYMQKS 432
+H+++ + +T + L++++K + K L + K + + + +S
Sbjct: 129 SHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSES 188
Query: 433 LELREKQAEKEEKQKTKKIETSAEKLRKLLKEEKRLKKKRRKSTSSS 479
+ E +A+K K+ +++ E + EK +K K +K KKK++K+ SSS
Sbjct: 189 EYIEEVRAKK--KKSSEEREKATEKTKKKKKHKKHSKKKKKKAASSS 233
Score = 35.8 bits (81), Expect = 0.15
Identities = 36/144 (25%), Positives = 54/144 (37%), Gaps = 6/144 (4%)
Query: 549 NHKQEVEK-----LLGKQDRLQYEKTQIKEKDRCPLSSSSLEIPDDFGGRSEDPRDFYNS 603
N K+E+EK L G + + + + KEK + SSS D S D D
Sbjct: 58 NWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKK 117
Query: 604 YKTQAGSSKTEKPYKSERHFSSRRNSSDSFCRNSEDKIYGYRRFEKDIEGRKEHYRRWEP 663
+ K SE S + S + + G + EKDI+G + + +
Sbjct: 118 QGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEK-EKDIKGLSKKRKMYSE 176
Query: 664 GSVRHSTSPASSEYSWKSVEKYKK 687
S S + SEY + K KK
Sbjct: 177 DKPLSSESLSESEYIEEVRAKKKK 200
>gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]
Length = 247
Score = 62.4 bits (150), Expect = 2e-09
Identities = 56/223 (25%), Positives = 102/223 (45%), Gaps = 25/223 (11%)
Query: 414 TFKDAEDALQKLHKYMQKSLELREKQAEKEEKQKTKKIETSAEKLRKLLKEEKRLKKKRR 473
T+++ ++ L+K K + E EK E +K+ K E K+ +R KK+++
Sbjct: 40 TWEEVKEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKK 99
Query: 474 KS-TSSSSVSSADESVSSSSSSSSSGHKRHKKHKRNRSESSRSSRRHSSRASSNQIDQNR 532
KS SSS SS+ +S SSSS S K+ K+ K+ ++ S +SS S S+ D +
Sbjct: 100 KSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLK 159
Query: 533 KDECYPVPANTSASFLNHKQEVEKLLGKQDRLQYEKTQIKEKDRCPLSSSSL---EIPDD 589
K + S +++++ L K+ +K PLSS SL E ++
Sbjct: 160 KKK-------KSKDGTEKEKDIKGLSKKRKMYSEDK---------PLSSESLSESEYIEE 203
Query: 590 FGGRSEDPRDFYNSYKTQAGSSKTEKPYKSERHFSSRRNSSDS 632
+ + +S + + + KT+K K ++H ++ + S
Sbjct: 204 VRAKKKK-----SSEEREKATEKTKKKKKHKKHSKKKKKKAAS 241
Score = 39.3 bits (90), Expect = 0.014
Identities = 29/128 (22%), Positives = 56/128 (43%), Gaps = 14/128 (10%)
Query: 393 EEEEKFLNAESYYKKALALDETFKDAEDALQKLHKYMQKSLELREKQAEKEEKQKTKKIE 452
E+E+K KK + + K +E ++ + + SL+ ++K + EK+K K
Sbjct: 122 EDEDKKQGKRRKKKK----NRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKDIK-- 175
Query: 453 TSAEKLRKLLKEEKRLKKKRRKST-------SSSSVSSADESVSSSSSSSSSGHKRHKKH 505
K RK+ E+K L + + + SS + ++ + HK+H K
Sbjct: 176 -GLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEEREKATEKTKKKKKHKKHSKK 234
Query: 506 KRNRSESS 513
K+ ++ SS
Sbjct: 235 KKKKAASS 242
Score = 37.0 bits (84), Expect = 0.069
Identities = 25/107 (23%), Positives = 55/107 (51%), Gaps = 2/107 (1%)
Query: 373 THRNARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALDETFKDAEDALQKLHKYMQKS 432
+H+++ + +T + L++++K + K L + K + + + +S
Sbjct: 139 SHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSES 198
Query: 433 LELREKQAEKEEKQKTKKIETSAEKLRKLLKEEKRLKKKRRKSTSSS 479
+ E +A+K K+ +++ E + EK +K K +K KKK++K+ SSS
Sbjct: 199 EYIEEVRAKK--KKSSEEREKATEKTKKKKKHKKHSKKKKKKAASSS 243
Score = 35.8 bits (81), Expect = 0.15
Identities = 36/144 (25%), Positives = 54/144 (37%), Gaps = 6/144 (4%)
Query: 549 NHKQEVEK-----LLGKQDRLQYEKTQIKEKDRCPLSSSSLEIPDDFGGRSEDPRDFYNS 603
N K+E+EK L G + + + + KEK + SSS D S D D
Sbjct: 68 NWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKK 127
Query: 604 YKTQAGSSKTEKPYKSERHFSSRRNSSDSFCRNSEDKIYGYRRFEKDIEGRKEHYRRWEP 663
+ K SE S + S + + G + EKDI+G + + +
Sbjct: 128 QGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEK-EKDIKGLSKKRKMYSE 186
Query: 664 GSVRHSTSPASSEYSWKSVEKYKK 687
S S + SEY + K KK
Sbjct: 187 DKPLSSESLSESEYIEEVRAKKKK 210
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 61.2 bits (147), Expect = 3e-09
Identities = 47/197 (23%), Positives = 92/197 (46%), Gaps = 14/197 (7%)
Query: 414 TFKDAEDALQKLHKYMQKSLELREKQAEKEEKQKTKKIETSAEKLRKLLKEEKRLKKK-- 471
T ++ ++ L+K + + L++++ E+EE++K ++ E + ++ +EE+R K++
Sbjct: 226 TVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERAR 285
Query: 472 -RRKSTSSSSVSSADESVSSSSSSSSSGHKRHKKHKRNRSES---------SRSSRRHSS 521
R + S S S S S S HKR + +R RS S RS R+H S
Sbjct: 286 DRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRS 345
Query: 522 RASSNQIDQNRKDECYPVPANTSASFLNHKQEVEKLLGKQDRLQYEKTQIKEKDRCPLSS 581
R+ + ++R + Y + + + K + ++ G D+ K+ +EK ++
Sbjct: 346 RSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNT 405
Query: 582 SSLE--IPDDFGGRSED 596
S E ++ G SED
Sbjct: 406 ESKESDTKNEVNGTSED 422
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 61.2 bits (147), Expect = 3e-09
Identities = 47/197 (23%), Positives = 92/197 (46%), Gaps = 14/197 (7%)
Query: 414 TFKDAEDALQKLHKYMQKSLELREKQAEKEEKQKTKKIETSAEKLRKLLKEEKRLKKK-- 471
T ++ ++ L+K + + L++++ E+EE++K ++ E + ++ +EE+R K++
Sbjct: 226 TVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERAR 285
Query: 472 -RRKSTSSSSVSSADESVSSSSSSSSSGHKRHKKHKRNRSES---------SRSSRRHSS 521
R + S S S S S S HKR + +R RS S RS R+H S
Sbjct: 286 DRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRS 345
Query: 522 RASSNQIDQNRKDECYPVPANTSASFLNHKQEVEKLLGKQDRLQYEKTQIKEKDRCPLSS 581
R+ + ++R + Y + + + K + ++ G D+ K+ +EK ++
Sbjct: 346 RSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNT 405
Query: 582 SSLE--IPDDFGGRSED 596
S E ++ G SED
Sbjct: 406 ESKESDTKNEVNGTSED 422
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 60.1 bits (144), Expect = 8e-09
Identities = 87/387 (22%), Positives = 159/387 (41%), Gaps = 58/387 (14%)
Query: 393 EEEEKFLNAESYYKKALALDETFKDAEDALQKLHKYMQKSLELREKQAEK-EEKQKTKKI 451
E+E++ L+ + ++ + K+ + + K + LE RE + EK++T
Sbjct: 430 EKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSL-LEAREADGDVVNEKKRTPNE 488
Query: 452 ETSAEKLRKLLKEEKRLKKKRRKSTSSSSVSSADESVSSSSSSSSSGH------------ 499
TS + +K KE+++ + R S+SS S SS + S+SS+ SSS +
Sbjct: 489 TTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSR 548
Query: 500 ----KRHKKHKRNRSESSRSSRRHSSRASSN--QIDQNRKDECYPVPANTSASFLNHKQE 553
KR K+H R+RS + + +RR SR+ S +I+ NR V + E
Sbjct: 549 SSSPKRKKRHSRSRSPTIK-ARRSRSRSYSRRIKIESNRA----RVKIRDRRRSNRNSIE 603
Query: 554 VEKLLGKQDRLQYEKTQIKEKDRCPLSSSSLEIPDDFGGRSEDPRDFYNSYKTQAGSSKT 613
E+ + + +++ + +DR +S RS D R + +G+S
Sbjct: 604 RERRRNRSPSRERRRSRSRSRDRRTNRASR--------SRSRDRRKIDDQRGNLSGNSHK 655
Query: 614 EKPYKSERHFSSRRNSSDSFCRNSEDKIYGYRRFEKDIEGRKEHYRRWEPGSVRHSTSPA 673
K E+ R+ S R +DK E++ + RKE +R E + +
Sbjct: 656 HKGEAKEQERKKERSRSIDKDRKKKDK-----EREREQDKRKEKQKREE----KDFKFSS 706
Query: 674 SSEYSWKSVEKYKKYAHSGS------RDFSRHEQRYRLNTNQGEYEREDNYG-------- 719
+ + E + ++ SGS R SR + + + ++ D+ G
Sbjct: 707 QDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPG 766
Query: 720 --EDIKTEVPEEDALSSKEHSESSVKK 744
++ K + P+ S E S+ S KK
Sbjct: 767 SSKEKKAKKPKHSRSRSVEKSQRSGKK 793
Score = 45.8 bits (107), Expect = 1e-04
Identities = 36/148 (24%), Positives = 70/148 (47%), Gaps = 10/148 (6%)
Query: 388 RGGQLEEEEKFLNAESYYKKALALDETFKDAEDALQKLHKYMQKSLELREKQAEKEEKQK 447
+G E+E K + S K D+ + +D ++ K +K + + + K++
Sbjct: 657 KGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRE 716
Query: 448 TKKIETSAEKLR-KLLKEEKRLKKKRRKSTSSSSVSSADESVSSSSSS-SSSGHKRHKKH 505
+++ + + + K+++ + R K+ + S S +D S SSS S SS K+ KK
Sbjct: 717 SERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKP 776
Query: 506 KRNRSES--------SRSSRRHSSRASS 525
K +RS S ++SR+H S++ S
Sbjct: 777 KHSRSRSVEKSQRSGKKASRKHKSKSRS 804
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 60.1 bits (144), Expect = 8e-09
Identities = 87/387 (22%), Positives = 159/387 (41%), Gaps = 58/387 (14%)
Query: 393 EEEEKFLNAESYYKKALALDETFKDAEDALQKLHKYMQKSLELREKQAEK-EEKQKTKKI 451
E+E++ L+ + ++ + K+ + + K + LE RE + EK++T
Sbjct: 430 EKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSL-LEAREADGDVVNEKKRTPNE 488
Query: 452 ETSAEKLRKLLKEEKRLKKKRRKSTSSSSVSSADESVSSSSSSSSSGH------------ 499
TS + +K KE+++ + R S+SS S SS + S+SS+ SSS +
Sbjct: 489 TTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSR 548
Query: 500 ----KRHKKHKRNRSESSRSSRRHSSRASSN--QIDQNRKDECYPVPANTSASFLNHKQE 553
KR K+H R+RS + + +RR SR+ S +I+ NR V + E
Sbjct: 549 SSSPKRKKRHSRSRSPTIK-ARRSRSRSYSRRIKIESNRA----RVKIRDRRRSNRNSIE 603
Query: 554 VEKLLGKQDRLQYEKTQIKEKDRCPLSSSSLEIPDDFGGRSEDPRDFYNSYKTQAGSSKT 613
E+ + + +++ + +DR +S RS D R + +G+S
Sbjct: 604 RERRRNRSPSRERRRSRSRSRDRRTNRASR--------SRSRDRRKIDDQRGNLSGNSHK 655
Query: 614 EKPYKSERHFSSRRNSSDSFCRNSEDKIYGYRRFEKDIEGRKEHYRRWEPGSVRHSTSPA 673
K E+ R+ S R +DK E++ + RKE +R E + +
Sbjct: 656 HKGEAKEQERKKERSRSIDKDRKKKDK-----EREREQDKRKEKQKREE----KDFKFSS 706
Query: 674 SSEYSWKSVEKYKKYAHSGS------RDFSRHEQRYRLNTNQGEYEREDNYG-------- 719
+ + E + ++ SGS R SR + + + ++ D+ G
Sbjct: 707 QDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPG 766
Query: 720 --EDIKTEVPEEDALSSKEHSESSVKK 744
++ K + P+ S E S+ S KK
Sbjct: 767 SSKEKKAKKPKHSRSRSVEKSQRSGKK 793
Score = 45.8 bits (107), Expect = 1e-04
Identities = 36/148 (24%), Positives = 70/148 (47%), Gaps = 10/148 (6%)
Query: 388 RGGQLEEEEKFLNAESYYKKALALDETFKDAEDALQKLHKYMQKSLELREKQAEKEEKQK 447
+G E+E K + S K D+ + +D ++ K +K + + + K++
Sbjct: 657 KGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRE 716
Query: 448 TKKIETSAEKLR-KLLKEEKRLKKKRRKSTSSSSVSSADESVSSSSSS-SSSGHKRHKKH 505
+++ + + + K+++ + R K+ + S S +D S SSS S SS K+ KK
Sbjct: 717 SERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKP 776
Query: 506 KRNRSES--------SRSSRRHSSRASS 525
K +RS S ++SR+H S++ S
Sbjct: 777 KHSRSRSVEKSQRSGKKASRKHKSKSRS 804
>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
Length = 248
Score = 59.3 bits (142), Expect = 1e-08
Identities = 53/181 (29%), Positives = 80/181 (44%), Gaps = 26/181 (14%)
Query: 419 EDALQKLHKYMQKSLELREKQAEKEEKQKTKKIETSAEKL----RKLLKEEKRLKKKRRK 474
E+ ++L S L E + + E K K++E S EKL K+ +R KK+++K
Sbjct: 42 EEVKKQLENKKTGSKALAEFEEKMNENWK-KELEKSREKLLSGNESSSKKRERKKKRKKK 100
Query: 475 STSSSSVSSADESVSSSSSSSSSGHK--RHKKHKRNRSESSRSSRRHSSRASSNQIDQNR 532
S SSS SS+ +S SSSS S K + +K K+NRS S S H S + S + + +
Sbjct: 101 SCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKK 160
Query: 533 K-------------------DECYPVPANTSASFLNHKQEVEKLLGKQDRLQYEKTQIKE 573
K + YP S+ + E + K+ R E+ Q KE
Sbjct: 161 KKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKE 220
Query: 574 K 574
K
Sbjct: 221 K 221
Score = 41.2 bits (95), Expect = 0.004
Identities = 35/142 (24%), Positives = 65/142 (45%), Gaps = 26/142 (18%)
Query: 393 EEEEKFLNAESYYKKALALDETFKDAEDALQKLHKYMQKSLELREKQAEKEEKQKTKKIE 452
E+EEK KK + ++K ++ + + ++S+ ++K+ K+E +K K +
Sbjct: 121 EDEEKKQGKRRKKKK----NRSYKSSQSSTHESESESKESV--KKKKKSKDETEKEKDVR 174
Query: 453 TSAEKLRKLLKEEKRLKKKRRKSTSSSSVSSADESVSSSSSS------------SSSGHK 500
+ ++K +K ++K L S+ SSS S +E V + K
Sbjct: 175 SLSKKRKKSYPDDKPL------SSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKK 228
Query: 501 RHKKHKRNRSESSRSSRRHSSR 522
+HKKH + + + S SS H SR
Sbjct: 229 QHKKHSKKKKKKSGSS--HKSR 248
>gi|40068059 CBF1 interacting corepressor [Homo sapiens]
Length = 450
Score = 58.9 bits (141), Expect = 2e-08
Identities = 54/221 (24%), Positives = 104/221 (47%), Gaps = 17/221 (7%)
Query: 431 KSLELREKQA-----EKEEKQKTKKIETSAEKLRKLLKEEKRLKKKRRKSTSSSSVSSAD 485
KSL ++KQ ++ EK+K KK K +K K + KK + S+SSSS SS+
Sbjct: 214 KSLTTKQKQKLLRKLDRLEKKKKKK----DRKKKKFQKSRSKHKKHKSSSSSSSSSSSSS 269
Query: 486 ESVSSSSSSSSSGHKRHKKHKRNRSESSRSSRRHSSRASSNQIDQNRKDECYPVPANTSA 545
+ +S SSS S + + KK +R + + ++ S ++S S + D+++K + + S+
Sbjct: 270 STETSESSSESESNNKEKKIQRKKRKKNKCSGHNNS--DSEEKDKSKKRKLH---EELSS 324
Query: 546 SFLNHKQEVEKLLGKQDRLQYEKTQIKEKDRCPLSSSSLEIPDDFGGRSEDPRDFYNSYK 605
S N ++ EK + E ++ D S + P+ G ++ + +
Sbjct: 325 SHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGRE 384
Query: 606 TQAGSSKTEKP--YKS-ERHFSSRRNSSDSFCRNSEDKIYG 643
++ S++ P YK E ++RN + R ++ + +G
Sbjct: 385 ERSRRSRSRSPGSYKQRETRKRAQRNPGEEQSRRNDSRSHG 425
Score = 36.2 bits (82), Expect = 0.12
Identities = 33/164 (20%), Positives = 62/164 (37%), Gaps = 13/164 (7%)
Query: 383 QTLVERGGQLEEEEKFLNA------ESYYKKALALDETFKDAEDALQKLHKYMQKSLELR 436
Q V G+ + E +FL + + +K L++ K + +K K K + +
Sbjct: 197 QEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHK 256
Query: 437 EKQAEKEEKQKTKKIETSAEKLR-KLLKEEKRLKKKRRKSTSSSSVSSADESVSSSSSSS 495
+ + ETS + +EK++++K+RK S +++D S
Sbjct: 257 SSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKR 316
Query: 496 ------SSGHKRHKKHKRNRSESSRSSRRHSSRASSNQIDQNRK 533
SS H +K K S R S+ S + D+ +
Sbjct: 317 KLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSR 360
>gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing
protein) [Homo sapiens]
Length = 543
Score = 58.5 bits (140), Expect = 2e-08
Identities = 45/149 (30%), Positives = 70/149 (46%), Gaps = 8/149 (5%)
Query: 307 ALKCVKIGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFEL 366
ALK ++G D +K A+ Y+KA E+D N+ + + A+Y KG NK E E
Sbjct: 225 ALKEKELGNDAYKKKDFDTALKHYDKAKELDPTNMTYITNQAAVYFEKGDYNKCRELCEK 284
Query: 367 ALENCPTHRNARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALDET------FKDAED 420
A+E +R + + + G +EEK+ +A +Y K+LA T + AE
Sbjct: 285 AIEVGRENREDYRQIAKAYARIGNSYFKEEKYKDAIHFYNKSLAEHRTPDVLKKCQQAEK 344
Query: 421 ALQKLHK--YMQKSLELREKQAEKEEKQK 447
L++ + Y+ L L EK E QK
Sbjct: 345 ILKEQERLAYINPDLALEEKNKGNECFQK 373
Score = 45.1 bits (105), Expect = 3e-04
Identities = 27/111 (24%), Positives = 53/111 (47%), Gaps = 7/111 (6%)
Query: 314 GVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPT 373
G + F+ G + AM Y +A++ + ++ + LY+ + + + +F+LAL++C
Sbjct: 367 GNECFQKGDYPQAMKHYTEAIKRNPKDAK-------LYSNRAACYTKLLEFQLALKDCEE 419
Query: 374 HRNARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALDETFKDAEDALQK 424
+ + LE + + A Y+KAL LD + K+A D Q+
Sbjct: 420 CIQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDLDSSCKEAADGYQR 470
Score = 34.3 bits (77), Expect = 0.45
Identities = 18/44 (40%), Positives = 24/44 (54%)
Query: 320 VGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIED 363
VG DA+ Y++A+++D N R A YA KG KA ED
Sbjct: 17 VGNIDDALQCYSEAIKLDPHNHVLYSNRSAAYAKKGDYQKAYED 60
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 57.4 bits (137), Expect = 5e-08
Identities = 69/363 (19%), Positives = 144/363 (39%), Gaps = 37/363 (10%)
Query: 387 ERGGQLEEEEKFLNAESYYKKALALDETFKDAEDALQKLHKYMQKSLELREKQA------ 440
ER + ++EE+ ++ +A E + A L + ++ L E+Q
Sbjct: 752 ERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFL 811
Query: 441 -EKEEKQKTKKIETSAEKLRKLLKEEKRLKKKRRKSTSSSSVSSADESVSSSSSSSSSGH 499
E+EEK++ ++ EK + L+EE++L+++ R + + ++ + S
Sbjct: 812 PEEEEKEQRRRQRREREKELQFLEEEEQLQRRER----AQQLQEEEDGLQEDQERRRSQE 867
Query: 500 KRHKKHKRNRSESSRSSRRHSSRASSNQIDQNRKDECY----PVPANTSASFLNHKQEVE 555
+R + R + E R RRH+ A +Q RK++ +QE E
Sbjct: 868 QRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQE 927
Query: 556 KLLGKQDRLQYEKTQIKEKDRCPLSSSSLEIPDDFGGRSEDPRDFYNSYKTQAGSSKT-- 613
+ ++++LQ E+ Q+ ++R + R E R + K Q +
Sbjct: 928 RQYREEEQLQQEEEQLLREER------------EKRRRQERERQYRKDKKLQQKEEQLLG 975
Query: 614 EKPYKSERHFSSRRNSSDSFCRNSEDKIYGYRRFEKDIEGRKEHYRRWEPGSVRHSTSPA 673
E+P K R ++ + + E+++ R E++ R+E R++ R
Sbjct: 976 EEPEKRRRQEREKKYREEEELQQEEEQLL---REEREKRRRQEWERQY-----RKKDELQ 1027
Query: 674 SSEYSWKSVEKYKKYAHSGSRDFSRHEQRYRLNTNQGEYEREDNYGEDIKTEVPEEDALS 733
E E+ K+ R + E+ + ERE ++++ + +E+ L
Sbjct: 1028 QEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQ 1087
Query: 734 SKE 736
+E
Sbjct: 1088 QEE 1090
Score = 56.6 bits (135), Expect = 8e-08
Identities = 75/362 (20%), Positives = 143/362 (39%), Gaps = 39/362 (10%)
Query: 391 QLEEEEKFLNAESYYKKALALDETFKDAEDALQKLHKYMQKSLELREKQAEKEEKQKTKK 450
QLEEE K Y K AL E + + LQ+ + +Q+ E REK+ +E++++ ++
Sbjct: 877 QLEEERKRRRHTLYAKPAL--QEQLRKEQQLLQEEEEELQR--EEREKRRRQEQERQYRE 932
Query: 451 IETSAEKLRKLLKEEK---RLKKKRRKSTSSSSVSSADESVSSSSSSSSSGHKRHKKHK- 506
E ++ +LL+EE+ R +++ R+ + +E + +R KK++
Sbjct: 933 EEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYRE 992
Query: 507 ----RNRSESSRSSRRHSSRASSNQIDQNRKDECYPVPANTSASFLNHKQEVEKLLGKQD 562
+ E R R + +KDE +QE E+LL
Sbjct: 993 EEELQQEEEQLLREEREKRRRQEWERQYRKKDEL--------------QQEEEQLL---- 1034
Query: 563 RLQYEKTQIKEKDRCPLSSSSLEIPDD--FGGRSEDPR--DFYNSYKTQAGSSKTEKPYK 618
R + EK +++E++R L+ ++ G E R + Y+ + + E+
Sbjct: 1035 REEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLL 1094
Query: 619 SERHFSSRRNSSDSFCRNSEDKIYGYRRFEKDIEGRKEHYRRWE-PGSVRHSTSPASSEY 677
E RR + CR E+ + E+ + +E RR E R E
Sbjct: 1095 REEPEKRRRQERERQCREEEEL---QQEEEQLLREEREKRRRQELERQYREEEEVQQEEE 1151
Query: 678 SWKSVEKYKKYAHSGSRDFSRHEQRYRLNTNQGEYEREDNYGEDIKTEVPEEDALSSKEH 737
E K+ R + R E+ + Q E ++ ++ + + EE+ L ++
Sbjct: 1152 QLLREEPEKRRRQELERQY-REEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKR 1210
Query: 738 SE 739
+
Sbjct: 1211 KQ 1212
Score = 43.5 bits (101), Expect = 7e-04
Identities = 54/281 (19%), Positives = 115/281 (40%), Gaps = 35/281 (12%)
Query: 392 LEEEEKFLNAESYYKKALALDETFKDAEDALQKLHKYMQKSLELREKQAEKEEKQKTKKI 451
LEEE + E + D F++ E LQ+ + + E R+++ +EE+Q ++
Sbjct: 1646 LEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQE-RDRKFREEEQQLRRQ- 1703
Query: 452 ETSAEKLRKLLKEEKRLKKKRRKSTSSSSVSSADESVSSSSSSSSSGHKRHKKHKRNRSE 511
E+ RK L+EE++L+++ + E+ +R +++++ E
Sbjct: 1704 ----ERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQL-------RRQERYRKILEE 1752
Query: 512 SSRSSRRHSSRASSNQIDQNRKDECYPVPANTSASFLNHKQEVEKLLGKQ-DRLQYEKTQ 570
R + + D+ ++E L ++E ++L ++ DR E+ Q
Sbjct: 1753 EQLRPEREEQQLRRQERDRKFREE----------EQLRQEREEQQLRSQESDRKFREEEQ 1802
Query: 571 IKEKDRCPLSSSSLEIPDDFGGRSEDPRDFYNSYKTQAGSSKTEKPYKSERHFSSR---R 627
++++ L G + + Q + ++ Y++E F+++ R
Sbjct: 1803 LRQERE----EQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSR 1858
Query: 628 NSSDSFCRNSEDKIYGYRRFEKDIEGRKEHYRRWEPGSVRH 668
+ E K RR E++ + R+EH RR + RH
Sbjct: 1859 REEQELWQEEEQK----RRQERERKLREEHIRRQQKEEQRH 1895
Score = 42.0 bits (97), Expect = 0.002
Identities = 68/380 (17%), Positives = 148/380 (38%), Gaps = 60/380 (15%)
Query: 387 ERGGQLEEEEKFLNAESYYKKALALDETFKDAEDALQKLHKYMQKSLELREKQAEKEEKQ 446
+R Q EEE+++ E+ +K E+ LQ+ Q+ L+ E+Q K E+Q
Sbjct: 235 DRVFQEEEEKEWRKRETVLRKE----------EEKLQEEEPQRQRELQEEEEQLRKLERQ 284
Query: 447 KTKKIETSAEKLRKLLKEEKRLKKKRRKSTSSSSVSSADESVSSSSSSSSSGHKRHKKHK 506
+ ++ E+ ++ L+ E++L++K+ + E +R ++
Sbjct: 285 ELRRERQEEEQQQQRLRREQQLRRKQEEERREQ-----QEERREQQERREQQEERREQQL 339
Query: 507 RNRSESSRSSRRHSSRASSNQIDQNRKDECYPVPANTSASFLNHKQEV--EKLLGKQDRL 564
R E R + + + Q R+++ L +Q++ E+ L ++ +L
Sbjct: 340 RREQEERREQQLRREQEEERREQQLRREQ----EEERREQQLRREQQLRREQQLRREQQL 395
Query: 565 QYEKTQIKEKDRCPLSSSSLEIPDDFGGRSEDPRDFYNSYKTQAGSSKTEKPYKSERHFS 624
+ E+ +E+ R + R + Q + E+ ++H
Sbjct: 396 RREQQLRREQQL---------------RREQQLRREQQLRREQQLRREQEEERHEQKHEQ 440
Query: 625 SRRNSSDSFCRNSEDKIYGYRRFEKDIEGRKEHYRRWEPGSVRHSTSPASSEYSWKSVEK 684
RR +R +++ E R++ +R E + RH + + E+
Sbjct: 441 ERRE----------------QRLKREQEERRDWLKR-EEETERHEQERRKQQLK-RDQEE 482
Query: 685 YKKYAHSGSRDFSRHEQRYRLNTNQGEYEREDNYGEDIKTEVPEEDALSSKEHSESSVKK 744
++ + R EQ+ R Q E+E+ + +K + EE+ L + SE +++
Sbjct: 483 ERRERWLKLEEEERREQQER-REQQLRREQEERREQRLKRQ-EEEERLQQRLRSEQQLRR 540
Query: 745 NLPQNLLNIFNQIAEFEKEK 764
+ Q+ + E+EK
Sbjct: 541 EQEERR----EQLLKREEEK 556
Score = 42.0 bits (97), Expect = 0.002
Identities = 66/372 (17%), Positives = 141/372 (37%), Gaps = 23/372 (6%)
Query: 387 ERGGQLEEEEKFLNAESYYKKALALDETFKDAEDALQKLHKYMQKSLELREKQAEKEEKQ 446
E+G + EEE+ L + +K L ++ + ++ Q+L + + E+Q ++E+
Sbjct: 1371 EQGRKFLEEEQRLRRQERERKFLKEEQQLR-CQEREQQLRQDRDRKFREEEQQLSRQERD 1429
Query: 447 KTKKIETS----AEKLRKLLKEEKRLKKKRRKSTSSSSVSSADESVSSSSSSSSSGHKRH 502
+ + E E+ RK L+EE++L+++R + +
Sbjct: 1430 RKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLE 1489
Query: 503 KKHKRNRSESSRSSRRHSSRASSNQIDQNRKDECYPVPANTSASFLNHKQEVEKLLGKQD 562
++ + R E R R R+ + + ++E FL +Q++ + Q
Sbjct: 1490 EEQQLRRQERDRKFREQELRSQEPE-RKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQ 1548
Query: 563 RLQ------YEKTQIK-EKDRCPLS----SSSLEIPDDFGGRSEDPRDFYNSYKTQAGSS 611
R Q E+ Q++ E++ LS + + R E R F + Q
Sbjct: 1549 RRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMED-EQQLRRQ 1607
Query: 612 KTEKPYKSERHFSSRRNSSDSFCRNSEDKIYGYRRFEKDIEGRKEHYRRWEPGSVRHSTS 671
+ ++ + ER R E +++ R K +E + R+ +RH
Sbjct: 1608 EGQQQLRQERD-RKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRD 1666
Query: 672 P--ASSEYSWKSVEKYKKYAHSGSRDFSRHEQRYRLNTNQGEYEREDNY--GEDIKTEVP 727
E + E+ + R F EQ+ R + ++ +E+ ++++ +
Sbjct: 1667 RKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFR 1726
Query: 728 EEDALSSKEHSE 739
EE+ L + E
Sbjct: 1727 EEEQLRQETEQE 1738
Score = 41.6 bits (96), Expect = 0.003
Identities = 64/370 (17%), Positives = 137/370 (37%), Gaps = 34/370 (9%)
Query: 387 ERGGQLEEEEKFLNAESYYKKALALDETFKDAEDALQKLHKYMQKSLELREKQAEKEEKQ 446
ER +LEEEE+ E ++ E ++ Q+ + +Q+ L ++ ++E++
Sbjct: 486 ERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEER 545
Query: 447 KTKKIETSAEKLRKLLKEEKRLKKKRRKSTSSSSVSSADESVSSSSSSSSSGHKRHKKHK 506
+ + ++ EK +L +E + + KR + + +E + ++ K
Sbjct: 546 REQLLKREEEK--RLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLK 603
Query: 507 RNRSESSRSSRRHSSRASSNQIDQNRKDECYPVPANTSASFLNHKQEVEKLLGKQDRLQY 566
R E R R + ++ R+ + L +++ E+ +Q +L+
Sbjct: 604 REEVERLEQEERREQRLKREEPEEERRQQ-----------LLKSEEQEER---RQQQLRR 649
Query: 567 EKTQIKEKDRCPLSSSSLEIPDDFGGRSEDPR---DFYNSYKTQAGSSKTEKPYKSERHF 623
E+ + +E+ R + E+ R + + QA + K +
Sbjct: 650 EQQERREQ-RLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQL 708
Query: 624 SSRRNSSDSFCRNSEDKIYGYRRFEKDIE--GRKEHYRRWEPGSVRHSTSPASSE----- 676
S ++ S + K G RR ++ E R+E +W+ H +
Sbjct: 709 ESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFT 768
Query: 677 YSWKSVEKYKKYAHSGSRDFSRHEQRYRLNTNQGEYEREDNYGEDIKTEVPEEDALSSKE 736
+ W++ EK ++ S EQR R + +RE + +PEE+ +
Sbjct: 769 WQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRF-------LPEEEEKEQRR 821
Query: 737 HSESSVKKNL 746
+K L
Sbjct: 822 RQRREREKEL 831
Score = 41.6 bits (96), Expect = 0.003
Identities = 85/438 (19%), Positives = 171/438 (39%), Gaps = 82/438 (18%)
Query: 322 RHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTHRNARKYL 381
R + +Y K E+ ++ + L + + E+ EL E R R+
Sbjct: 1072 RRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKR 1131
Query: 382 CQTLVERGGQLEEEEKFLNAESYYKKALALDETFKDAEDALQKLHKYMQKSLELREKQAE 441
+ +ER Q EEE+ E + L +E K L++ ++ ++ L+ E+Q
Sbjct: 1132 RRQELER--QYREEEEVQQEE----EQLLREEPEKRRRQELERQYRE-EEELQQEEEQLL 1184
Query: 442 KEEKQKTKKIETSAEKLRKLLKEEKRLKKKRRKSTSSSSVSSADESVSSSSSSSSSGHKR 501
+EE++K + ++ + +EE+ L++++RK
Sbjct: 1185 REEQEKRR------QERERQYREEEELQRQKRK--------------------------- 1211
Query: 502 HKKHKRNRSESSRSS-------RRHSSRASSNQIDQNRKDECYPVPANTSASFLNHKQEV 554
+R R E RS + ++ + + R++E + ++ +Q++
Sbjct: 1212 ----QRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDL 1267
Query: 555 EKLLGKQ---DRLQYEKTQIKEKDRCPLSSSSLEIPDDFGGRSEDPRDFYNSYKTQAGSS 611
+ LLG+Q DR Q E+ + +++DR LE + + D + S
Sbjct: 1268 QHLLGEQQERDREQ-ERRRWQQRDRHFPEEEQLEREEQKEAKRRDRK-----------SQ 1315
Query: 612 KTEKPYKSERHFSSRRNSSDSFCRNSEDKIYGYRRFEKDIEGRKEHYRRWEPGSVRHSTS 671
+ ++ + ER RR +D R E + R E+ + R+E R++ +RH
Sbjct: 1316 EEKQLLREEREEKRRRQETDRKFREEEQLL--QEREEQPLR-RQERDRKFREEELRH--- 1369
Query: 672 PASSEYSWKSVEKYKKY-AHSGSRDFSRHEQRYRLNTNQGEYEREDNYGEDIKTEVPEED 730
E K +E+ ++ R F + EQ+ R ERE +D + EE+
Sbjct: 1370 ---QEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQ------EREQQLRQDRDRKFREEE 1420
Query: 731 ALSSKEHSESSVKKNLPQ 748
S++ + ++ Q
Sbjct: 1421 QQLSRQERDRKFREEEQQ 1438
Score = 41.6 bits (96), Expect = 0.003
Identities = 70/392 (17%), Positives = 147/392 (37%), Gaps = 57/392 (14%)
Query: 393 EEEEKFLNAESYYKKALALDETFKDAEDALQKLHKYMQKSLELREKQAEKEEKQKTKKIE 452
+E ++ + ++ + L+ ++ ++A ++ K ++ LRE++ EK +Q+T +
Sbjct: 1281 QERRRWQQRDRHFPEEEQLER--EEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKF 1338
Query: 453 TSAEKL-----------------------------RKLLKEEKRLKKKRRKSTSSSSVSS 483
E+L RK L+EE+RL+++ R+
Sbjct: 1339 REEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERE----RKFLK 1394
Query: 484 ADESVSSSSSSSSSGHKRHKKHKRNRSESSRSSRRHSSRASSNQIDQNRKDECYPVPANT 543
++ + R +K + + SR R R Q+ + ++ +
Sbjct: 1395 EEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQ 1454
Query: 544 SASFLNHK-QEVEKLLGKQDRLQYEKTQIKEKDRCPLSSSSLEIPDDFGGRSEDPRDFYN 602
+ K +E E+LL +++ Q + +E+DR L + R E R F
Sbjct: 1455 LRQERHRKFREEEQLLQEREEQQLHR---QERDRKFLEE------EQQLRRQERDRKF-- 1503
Query: 603 SYKTQAGSSKTEKPYKSERHFSSRRNSSDSFCRNSE----DKIYGYRRFEKDIEGRKEHY 658
+ + S + E+ + E R+ F + + + RR ++D + R+E
Sbjct: 1504 -REQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQ 1562
Query: 659 RRWEPGSVRHSTSPASSEYSWKSVEKYKKYAHSGSRDFSRHEQRYRLNTNQGE--YERED 716
R E + S ++ +E+ K R F EQ+ R Q + ER+
Sbjct: 1563 LRQEREEQQLSRQERDRKF---RLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDR 1619
Query: 717 NYGEDIKTEVPEEDALSSKEHSESSVKKNLPQ 748
+ ED + E+ ++ + + PQ
Sbjct: 1620 KFREDEQLLQEREEQQLHRQERDRKFLEEEPQ 1651
Score = 40.8 bits (94), Expect = 0.005
Identities = 61/323 (18%), Positives = 130/323 (40%), Gaps = 30/323 (9%)
Query: 420 DALQKLHKYMQKSLEL-REKQAEKEEKQKTKKIETSAEKLRKLLKEEKRLKKKRRKSTSS 478
D Q+ ++ Q+ E+Q E+EE+++ K+ + +++ ++LL+EE+ ++KRR+ +
Sbjct: 1278 DREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREER--EEKRRRQETD 1335
Query: 479 SSVSSADESVSSSSSSSSSGHKRHKKHKRNRSESSRSSRRHSSRASSNQIDQNRKDECYP 538
++ + +R ++ ++ R E R + Q + ++ E
Sbjct: 1336 RKFREEEQLLQEREEQPL---RRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKF 1392
Query: 539 VPANTSASFLNHKQEVEKLLGKQDRLQYEKTQIKEKDRCPLSSSSLEIPDDFGGRSEDPR 598
+ +Q++ + ++ R + ++ +E+DR + R E R
Sbjct: 1393 LKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDR------KFREEEQQVRRQERER 1446
Query: 599 DFYNSYKTQAGSSKTEKPYKSERHFSSRRNSSDSFCRNSEDKIYGYRRFEKDIEGRKEHY 658
F + E+ + ERH R E +++ R K +E ++
Sbjct: 1447 KFL----------EEEQQLRQERH-RKFREEEQLLQEREEQQLHRQERDRKFLE-EEQQL 1494
Query: 659 RRWEPGSVRHSTSPASSEYSWKSVEKYKK-YAHSGSRDFSRHEQRYRLNTNQGEYEREDN 717
RR E S E K +E+ ++ + R F + EQ+ R +G+ R+D
Sbjct: 1495 RRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLR-RQERGQQRRQDR 1553
Query: 718 ----YGEDIKTEVPEEDALSSKE 736
E+ + EE LS +E
Sbjct: 1554 DRKFREEEQLRQEREEQQLSRQE 1576
Score = 35.0 bits (79), Expect = 0.26
Identities = 62/348 (17%), Positives = 126/348 (36%), Gaps = 43/348 (12%)
Query: 394 EEEKFLNAESYYKKALALDETFKDAEDALQKLHKYMQKSLELREKQAEKEEKQKTKKIET 453
EEE+ L+ + +K L ++ + E Q+ +K E + + E+EE+Q +++
Sbjct: 1519 EEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQ--- 1575
Query: 454 SAEKLRKLLKEEKRLKKKRRKSTSSSSVSSADESVSSSSSSSSSGHKRHKKHKRNRSESS 513
E+ RK EE++++++ ++ E R ++ ++ R +
Sbjct: 1576 --ERDRKFRLEEQKVRRQEQERKFM-------EDEQQLRRQEGQQQLRQERDRKFREDEQ 1626
Query: 514 RSSRRHSSRASSNQIDQNRKDECYPVPANTSASFLNHKQEVEKLLGKQDRLQYEKTQIKE 573
R + + D+ +E + L H ++ + +Q + E+ Q++
Sbjct: 1627 LLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRR 1686
Query: 574 KDRCPLSSSSLEIPDDFGGRSEDPRDFYNSYKTQAGSSKTEKPYKSERHFSSRRNSSDSF 633
++R + R E R F + Q + E+ ++ E
Sbjct: 1687 QER----DRKFREEEQQLRRQERERKFLQE-EQQLRRQELERKFREEEQLRQETEQEQLR 1741
Query: 634 CRNSEDKIYG------------YRRFEKDIEGRKEHYRRWEPGSVRHSTSPASSEYSWKS 681
+ KI RR E+D + R+E R E E +S
Sbjct: 1742 RQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQE-----------REEQQLRS 1790
Query: 682 VEKYKKYAHSGSRDFSRHEQRYRLNTNQGEYEREDNYGEDIKTEVPEE 729
E +K+ R EQ+ R G+Y E+ E ++ E E+
Sbjct: 1791 QESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEE---EQLQLEEQEQ 1835
Score = 33.1 bits (74), Expect = 1.0
Identities = 56/335 (16%), Positives = 126/335 (37%), Gaps = 22/335 (6%)
Query: 417 DAEDALQKLHKYMQKSLELRE--KQAEKEEKQKTKKIETSAEKLRKLLKEEKRLKKKRRK 474
+ E ++ K ++ EL E +Q+EK+E+ + + + E+L + ++E + +++RR
Sbjct: 130 EEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWR-QRQEWQEREERRA 188
Query: 475 STSSSSVSSADESVSSSSSSSSSGHKRHKKHKRNRSESSRSSRRHSSRASSNQIDQN-RK 533
E+ + + ++ R E + R R + ++ RK
Sbjct: 189 EEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRK 248
Query: 534 DECYPVPANTSASFLNHKQE--VEKLLGKQDRLQYEKTQIKEKDRCPLSSSSLEIPDDFG 591
E + L ++E E+ +Q LQ E+ Q+++ +R L E +
Sbjct: 249 RE----------TVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQE-EEQQQ 297
Query: 592 GRSEDPRDFYNSYKTQAGSSKTEKPYKSERHFSSRRNSSDSFCRNSEDKIYGYRRFEKDI 651
R + + + + E+ + ER R E++ R E++
Sbjct: 298 QRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEE 357
Query: 652 EGRKEHYRRWEPGSVRHSTSPASSEYSWKSVEKYKKYAHSGSRDFSRHEQRYRLNTNQGE 711
E R++ RR + R E + ++ ++ R EQ+ R + +
Sbjct: 358 ERREQQLRREQEEERRE--QQLRREQQLRREQQLRREQQLRREQQLRREQQLR---REQQ 412
Query: 712 YEREDNYGEDIKTEVPEEDALSSKEHSESSVKKNL 746
RE + + +E+ ++H + ++ L
Sbjct: 413 LRREQQLRREQQLRREQEEERHEQKHEQERREQRL 447
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 55.5 bits (132), Expect = 2e-07
Identities = 51/187 (27%), Positives = 89/187 (47%), Gaps = 20/187 (10%)
Query: 436 REKQAEKE-EKQKTKKIETSAEKLRKLLKEEKRLKKKRRKSTSSSSVS----------SA 484
REK EK+ EK + ++ E EK R KE+++ K+K R+ S + +
Sbjct: 421 REKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTP 480
Query: 485 DESVSSSSSSSSSGHKRHKKHKRNRSESSRSS---RRHSSRA----SSNQIDQNRKDECY 537
S ++S S SS +R ++ R+ S S R+S +R SSR+ S N+ D+ R+ E
Sbjct: 481 PRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERD 540
Query: 538 PVPANTSASFLNHKQEVEKLLGKQDRLQYEKTQIKEKD--RCPLSSSSLEIPDDFGGRSE 595
+ ++ +++L+ T +KEK+ + P SS S E+ D R+E
Sbjct: 541 HISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTE 600
Query: 596 DPRDFYN 602
+ + +N
Sbjct: 601 ENKIQHN 607
Score = 54.3 bits (129), Expect = 4e-07
Identities = 52/193 (26%), Positives = 87/193 (45%), Gaps = 30/193 (15%)
Query: 416 KDAEDALQKLHKYMQKSLELREKQAEKE-EKQKTKKIETSAEKLRKLLKEEK-------- 466
KD E +K H+ + R+K+ EKE +K+K ++ + S E K K++K
Sbjct: 431 KDREREREKEHE------KDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSY 484
Query: 467 ---------RLKKKRRKSTSSSSVSSADESVSSSSSSSSSGHKRHKKHKRNRSESSR-SS 516
+++RR+S SSS +++ SS S S R+KK K+ E S
Sbjct: 485 NASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISE 544
Query: 517 RRHSSRASSNQIDQNRKDECYPVPAN-TSASFLNHKQE----VEKLLGKQDRLQYEKTQI 571
RR R++S + N +D + N TS H +E V K + +D + E+ +I
Sbjct: 545 RRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKI 604
Query: 572 KEKDRCPLSSSSL 584
+ C L+ +L
Sbjct: 605 QHNGNCQLNEENL 617
Score = 53.5 bits (127), Expect = 7e-07
Identities = 73/349 (20%), Positives = 134/349 (38%), Gaps = 32/349 (9%)
Query: 407 KALALDET-FKDAEDALQKLHKYMQKSLELREKQAEKEEKQKTKKIETSAEKLRKLLKEE 465
+ALA + F D + + + K E+ + A KE ++ K++ + + ++ E
Sbjct: 237 RALAFNGVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPE 296
Query: 466 KRLKKKRRKSTSSSSVSSADESVSSSSSSSSSGHKRHKKHKRNRSESSRSSRR-----HS 520
+R+ S S S S S S S +H+ NRS S + RR H
Sbjct: 297 SGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHK 356
Query: 521 SRASSNQIDQNRKDECYPVPANTSASFLNHKQEVEKLLGKQDRLQYEKTQIKEKDRCPLS 580
R+ S + ++R + + K+ V++ +++R + EK + KEK+R
Sbjct: 357 KRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKER-EREKEREKEKER---- 411
Query: 581 SSSLEIPDDFGGRSEDPRDFYNSYKTQAGSSKTEKPYKSERHFSSRRNSSDSFCRNSEDK 640
G+++D RD + K + + + H R + ++ E +
Sbjct: 412 -----------GKNKD-RDKEREKDREKDKEKDREREREKEHEKDRDKEKEKE-QDKEKE 458
Query: 641 IYGYRRFEKDIEGRKEHYRRWEPGSVRHSTSPASSEYSWKSVEKYKKYAHSGSRDFSRHE 700
R E D + +K+ R P S S SS S E+ ++ + S SR R
Sbjct: 459 REKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSS-----SRERRRRRSRSSSRS-PRTS 512
Query: 701 QRYRLNTNQGEYEREDNYGEDIKTEVPEEDALSSKEHSESSVKKNLPQN 749
+ + +++ R N + K E D +S + E S N
Sbjct: 513 KTIKRKSSRSPSPRSRNKKD--KKREKERDHISERRERERSTSMRKSSN 559
Score = 50.8 bits (120), Expect = 5e-06
Identities = 68/347 (19%), Positives = 122/347 (35%), Gaps = 18/347 (5%)
Query: 391 QLEEEEKFLNAESYYKKALALDETFKDAEDALQKLHKYMQKSLELREKQAEKEEKQKTKK 450
+LEE K + + A E+ K E + + + K + ++ ++K
Sbjct: 274 ELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKH 333
Query: 451 IETSAEKLRKLLKEEKRLKKKRRKSTSSSSVSSADESVSSSSSSSSSGHKRHKKHKRNRS 510
S + R K+ +R K +K + S + S + K +K +
Sbjct: 334 RSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEK 393
Query: 511 ESSRSSRRHSSRASSNQIDQNRKDECYPVPANTSASFLNHKQEVEKLLGKQDRLQYEKTQ 570
+ + R R + +N+ + + ++E EK K + EK Q
Sbjct: 394 DREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQ 453
Query: 571 IKEKDRCPLSSSSLEIPDDFGGRSEDPRDFYNSYKTQAGSSKTEKPYKSERHFSSRRNSS 630
KEK+R S ++ +S P YN+ + SS+ E+ + R S +S
Sbjct: 454 DKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSR-ERRRRRSRSSSRSPRTS 512
Query: 631 DSFCRNSEDKIYGYRRFEKDIEGRKEHYRRWEPGSVRHSTSPASSEYSWKSVEKYKKYAH 690
+ R S R +KD + KE E STS S
Sbjct: 513 KTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKS--------------- 557
Query: 691 SGSRDFSRHEQRYRLNTNQGEYEREDNYGEDIKTEVPEEDALSSKEH 737
S D E+ + +T+ E E + EV ++DA ++E+
Sbjct: 558 --SNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEEN 602
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 55.5 bits (132), Expect = 2e-07
Identities = 51/187 (27%), Positives = 89/187 (47%), Gaps = 20/187 (10%)
Query: 436 REKQAEKE-EKQKTKKIETSAEKLRKLLKEEKRLKKKRRKSTSSSSVS----------SA 484
REK EK+ EK + ++ E EK R KE+++ K+K R+ S + +
Sbjct: 305 REKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTP 364
Query: 485 DESVSSSSSSSSSGHKRHKKHKRNRSESSRSS---RRHSSRA----SSNQIDQNRKDECY 537
S ++S S SS +R ++ R+ S S R+S +R SSR+ S N+ D+ R+ E
Sbjct: 365 PRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERD 424
Query: 538 PVPANTSASFLNHKQEVEKLLGKQDRLQYEKTQIKEKD--RCPLSSSSLEIPDDFGGRSE 595
+ ++ +++L+ T +KEK+ + P SS S E+ D R+E
Sbjct: 425 HISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTE 484
Query: 596 DPRDFYN 602
+ + +N
Sbjct: 485 ENKIQHN 491
Score = 54.3 bits (129), Expect = 4e-07
Identities = 52/193 (26%), Positives = 87/193 (45%), Gaps = 30/193 (15%)
Query: 416 KDAEDALQKLHKYMQKSLELREKQAEKE-EKQKTKKIETSAEKLRKLLKEEK-------- 466
KD E +K H+ + R+K+ EKE +K+K ++ + S E K K++K
Sbjct: 315 KDREREREKEHE------KDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSY 368
Query: 467 ---------RLKKKRRKSTSSSSVSSADESVSSSSSSSSSGHKRHKKHKRNRSESSR-SS 516
+++RR+S SSS +++ SS S S R+KK K+ E S
Sbjct: 369 NASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISE 428
Query: 517 RRHSSRASSNQIDQNRKDECYPVPAN-TSASFLNHKQE----VEKLLGKQDRLQYEKTQI 571
RR R++S + N +D + N TS H +E V K + +D + E+ +I
Sbjct: 429 RRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKI 488
Query: 572 KEKDRCPLSSSSL 584
+ C L+ +L
Sbjct: 489 QHNGNCQLNEENL 501
Score = 53.5 bits (127), Expect = 7e-07
Identities = 73/349 (20%), Positives = 134/349 (38%), Gaps = 32/349 (9%)
Query: 407 KALALDET-FKDAEDALQKLHKYMQKSLELREKQAEKEEKQKTKKIETSAEKLRKLLKEE 465
+ALA + F D + + + K E+ + A KE ++ K++ + + ++ E
Sbjct: 121 RALAFNGVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPE 180
Query: 466 KRLKKKRRKSTSSSSVSSADESVSSSSSSSSSGHKRHKKHKRNRSESSRSSRR-----HS 520
+R+ S S S S S S S +H+ NRS S + RR H
Sbjct: 181 SGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHK 240
Query: 521 SRASSNQIDQNRKDECYPVPANTSASFLNHKQEVEKLLGKQDRLQYEKTQIKEKDRCPLS 580
R+ S + ++R + + K+ V++ +++R + EK + KEK+R
Sbjct: 241 KRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKER-EREKEREKEKER---- 295
Query: 581 SSSLEIPDDFGGRSEDPRDFYNSYKTQAGSSKTEKPYKSERHFSSRRNSSDSFCRNSEDK 640
G+++D RD + K + + + H R + ++ E +
Sbjct: 296 -----------GKNKD-RDKEREKDREKDKEKDREREREKEHEKDRDKEKEKE-QDKEKE 342
Query: 641 IYGYRRFEKDIEGRKEHYRRWEPGSVRHSTSPASSEYSWKSVEKYKKYAHSGSRDFSRHE 700
R E D + +K+ R P S S SS S E+ ++ + S SR R
Sbjct: 343 REKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSS-----SRERRRRRSRSSSRS-PRTS 396
Query: 701 QRYRLNTNQGEYEREDNYGEDIKTEVPEEDALSSKEHSESSVKKNLPQN 749
+ + +++ R N + K E D +S + E S N
Sbjct: 397 KTIKRKSSRSPSPRSRNKKD--KKREKERDHISERRERERSTSMRKSSN 443
Score = 50.8 bits (120), Expect = 5e-06
Identities = 68/347 (19%), Positives = 122/347 (35%), Gaps = 18/347 (5%)
Query: 391 QLEEEEKFLNAESYYKKALALDETFKDAEDALQKLHKYMQKSLELREKQAEKEEKQKTKK 450
+LEE K + + A E+ K E + + + K + ++ ++K
Sbjct: 158 ELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKH 217
Query: 451 IETSAEKLRKLLKEEKRLKKKRRKSTSSSSVSSADESVSSSSSSSSSGHKRHKKHKRNRS 510
S + R K+ +R K +K + S + S + K +K +
Sbjct: 218 RSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEK 277
Query: 511 ESSRSSRRHSSRASSNQIDQNRKDECYPVPANTSASFLNHKQEVEKLLGKQDRLQYEKTQ 570
+ + R R + +N+ + + ++E EK K + EK Q
Sbjct: 278 DREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQ 337
Query: 571 IKEKDRCPLSSSSLEIPDDFGGRSEDPRDFYNSYKTQAGSSKTEKPYKSERHFSSRRNSS 630
KEK+R S ++ +S P YN+ + SS+ E+ + R S +S
Sbjct: 338 DKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSR-ERRRRRSRSSSRSPRTS 396
Query: 631 DSFCRNSEDKIYGYRRFEKDIEGRKEHYRRWEPGSVRHSTSPASSEYSWKSVEKYKKYAH 690
+ R S R +KD + KE E STS S
Sbjct: 397 KTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKS--------------- 441
Query: 691 SGSRDFSRHEQRYRLNTNQGEYEREDNYGEDIKTEVPEEDALSSKEH 737
S D E+ + +T+ E E + EV ++DA ++E+
Sbjct: 442 --SNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEEN 486
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 55.1 bits (131), Expect = 2e-07
Identities = 31/122 (25%), Positives = 60/122 (49%), Gaps = 3/122 (2%)
Query: 406 KKALALDETFKDAEDALQKLHKYMQKSLELREKQAEKEEKQKTKKIETSAEKLRKLLKEE 465
KK +ET ++ E+ ++ K ++ + +EK+ EKE+K+KTK+ E EK + +++
Sbjct: 5 KKKKETEET-EETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEE--EKK 61
Query: 466 KRLKKKRRKSTSSSSVSSADESVSSSSSSSSSGHKRHKKHKRNRSESSRSSRRHSSRASS 525
++ K+K++K +E G +R KK KR R E ++ R +
Sbjct: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTK 121
Query: 526 NQ 527
+
Sbjct: 122 KK 123
Score = 43.9 bits (102), Expect = 6e-04
Identities = 29/97 (29%), Positives = 51/97 (52%), Gaps = 8/97 (8%)
Query: 387 ERGGQLEEEEKFLNAESYYKKALALDETFKDAEDALQKLHKYMQKSLELREKQAEKEEKQ 446
E+ G+ +E+ K E KK E K+ E+ +K + +K E E++ E+EE++
Sbjct: 24 EKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEE 83
Query: 447 KTKKIETSAE--------KLRKLLKEEKRLKKKRRKS 475
+ K+ E E K R+ +EE++ KK+RRK+
Sbjct: 84 EEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120
Score = 37.7 bits (86), Expect = 0.041
Identities = 18/98 (18%), Positives = 40/98 (40%)
Query: 436 REKQAEKEEKQKTKKIETSAEKLRKLLKEEKRLKKKRRKSTSSSSVSSADESVSSSSSSS 495
++K+ +K+E ++T++ E + E+ K K +++ K+KR++ ++
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 496 SSGHKRHKKHKRNRSESSRSSRRHSSRASSNQIDQNRK 533
KR KK + E + + RK
Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRK 98
Score = 35.8 bits (81), Expect = 0.15
Identities = 30/141 (21%), Positives = 57/141 (40%), Gaps = 28/141 (19%)
Query: 436 REKQAEKEEKQKTKKIETSAEKLRKLLKEEKRLKKKRRKSTSSSSVSSADESVSSSSSSS 495
++K+ E EE ++T++ E EK K ++EKR +K++ K + +
Sbjct: 4 KKKKKETEETEETEETEEEEEKEGK--RKEKRKEKRKEKEKKKKT-----KETEKRKEKE 56
Query: 496 SSGHKRHKKHKRNRSESSRSSRRHSSRASSNQIDQNRKDECYPVPANTSASFLNHKQEVE 555
KR +K K+ + E R ++ K+E K+E
Sbjct: 57 EEEKKRKRKRKKKKEEEEREEEEEE--------EEEEKEE-------------EEKEEGR 95
Query: 556 KLLGKQDRLQYEKTQIKEKDR 576
+ K+ R + E+ + K+K R
Sbjct: 96 RRKKKKKRRRKEEEEEKKKKR 116
>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
Length = 976
Score = 55.1 bits (131), Expect = 2e-07
Identities = 99/499 (19%), Positives = 196/499 (39%), Gaps = 68/499 (13%)
Query: 325 DAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTHRNA------- 377
D +N+ + ++ +N++ + + + L K +ED +++L+ + + A
Sbjct: 294 DKVNQLEEKTKLQSENLKQSIEK------QHHLTKELEDIKVSLQRSVSTQKALEEDLQI 347
Query: 378 -RKYLCQTLVERGGQLEEEEKFLNAESYY-----KKALALDETFKDAEDALQKLHKYMQ- 430
K +CQ E+ Q+EE K A S+ +L+E + + L+K ++
Sbjct: 348 ATKTICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKI 407
Query: 431 KSLELREKQAEKEEKQK-TKKIETSAEKLRKLLKEEKRLKKKRRKSTSSSSVSSADE--- 486
++EL++K +E EE K T E E+L+K+L E++ L + ++ + E
Sbjct: 408 LTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEELKGTEQEL 467
Query: 487 -------------------SVSSSSSSSSSGHKRHKKHKRNRSESSRSSRRHSSRAS--S 525
++++S S K K N + H ++ S +
Sbjct: 468 IGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLEN 527
Query: 526 NQIDQNRKDECYPVPANTSASFLNHKQEVEKLLGKQDRLQYEKTQIK---EKDRCPLSSS 582
++ Q D + N N+K++ E++L + + LQ +TQ++ E R L
Sbjct: 528 KELTQETSDMTLEL-KNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREELKQK 586
Query: 583 SLEIPDDFGGRSEDPRDFYNSYKTQAGSSKTEKPYKSERHFSSRRNSSDSFCRN-SEDKI 641
E+ E+ N K +K + + E ++ +++S N E K+
Sbjct: 587 RDEVKCKLDKSEENCN---NLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIKV 643
Query: 642 YGYRRFEKDIEGRKEHYRR-WEPGSVRHSTSPASSEYSWKSVEKYKKYAHSG---SRDFS 697
+ E ++E K+ + + S E + VEK K A ++
Sbjct: 644 ---NKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKVIADEAVKLQKEID 700
Query: 698 RHEQRYRLNTNQGEYEREDNYGEDIKTEVPEEDALSSKEHSESSVK-------KNLPQNL 750
+ Q + + Y + I+ E SKE +SS++ NL L
Sbjct: 701 KRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKSKEQEQSSLRASLEIELSNLKAEL 760
Query: 751 LNIFNQIAEFEKEKGNKSK 769
L++ Q+ E E+E+ K K
Sbjct: 761 LSVKKQL-EIEREEKEKLK 778
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 54.7 bits (130), Expect = 3e-07
Identities = 60/343 (17%), Positives = 127/343 (37%), Gaps = 11/343 (3%)
Query: 422 LQKLHKYMQKSLELREKQAEKEEKQKTKKIETSAEKLRKLLKEEKRLKKKRRKSTSSSSV 481
L + HK R +Q E+E +++ ++ E ++ K E+R +K R +
Sbjct: 42 LGQAHKDADGDDRERNRQKERERRREKRQTERETDR-----KRERRREKDRHRKRDRHRE 96
Query: 482 SSADESVSSSSSSSSSGHKRHKKHKRNRSESSRSSRRHSSRASSNQIDQNRKDECYPVPA 541
D + ++ +K + + E R + R R Q D R+ E
Sbjct: 97 RQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAE 156
Query: 542 NTSASFLNHKQEVEKLLGKQDRLQYEKTQIKEKDRCPLSSSSLEIPDDFGGRSEDPRDFY 601
+ +++ + +Q + EK + + ++R + D SE R+
Sbjct: 157 KERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTED---RHSERGRERE 213
Query: 602 NSYKTQAGSSKTEKPYKSERHFSSRRNSSDSFCRNSEDKIYGYRRFEKDIEGRKEHYRRW 661
+T+ ++TE+ +++R +R + + +E + R E+D E +E R
Sbjct: 214 RERETE---TETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDR 270
Query: 662 EPGSVRHSTSPASSEYSWKSVEKYKKYAHSGSRDFSRHEQRYRLNTNQGEYEREDNYGED 721
+ + + + E+ ++ R R +R R + E ERE
Sbjct: 271 DRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQ 330
Query: 722 IKTEVPEEDALSSKEHSESSVKKNLPQNLLNIFNQIAEFEKEK 764
+TE E K ++ + + + + AE E+E+
Sbjct: 331 RETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERER 373
Score = 45.1 bits (105), Expect = 3e-04
Identities = 56/274 (20%), Positives = 102/274 (37%), Gaps = 30/274 (10%)
Query: 413 ETFKDAEDALQKLHKYMQKSLELREKQAEKEEKQKT--------------KKIETSAEKL 458
E + E QK + + E RE++ ++E++ KT ++ ET E+
Sbjct: 166 ERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERK 225
Query: 459 RKLLKEEKRLKKKRRKSTSSSSVSSADESVSSSSSSSSSGHKRHKKHKRNRSESSRSSRR 518
R+ +E R +K R+ + A E + R + R + E R + R
Sbjct: 226 RQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDR 285
Query: 519 HSSRASSNQIDQNRKDECYPVPANTSASFLNHKQEVEKLLGKQDRLQYEKTQIKEKDRCP 578
R + + RK E N K+E E+ ++ Q E + +EK+R
Sbjct: 286 KRQRRTERDRETERKRERQRERERERER--NRKRERERERERERERQRETERDREKERER 343
Query: 579 LSSSSLEIPDDFGGRSEDPRDFYNSYKTQAGSSKTEKPYKSER---HFSSRRNSSDSFCR 635
E+ + N + G + E+ + ER S+R R
Sbjct: 344 KRKRQTEMDRE-----------RNRQTGREGRRQAERERERERERDRQSAREREERERDR 392
Query: 636 NSEDKIYGYRRFEKDIEGRKEHYRRWEPGSVRHS 669
+ + + R+ EKD +G++E ++ E R S
Sbjct: 393 DRDRQKERERQTEKDRDGQRETEKQREREKDRES 426
Score = 43.5 bits (101), Expect = 7e-04
Identities = 60/326 (18%), Positives = 116/326 (35%), Gaps = 56/326 (17%)
Query: 436 REKQAEKEE-KQKTKKIETSAEKLR--------KLLKEEKRLKKKRRKSTSSSSVSSADE 486
R++Q EKE +QK ++ ET E R + +E +R +K R+ + E
Sbjct: 113 RDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTE 172
Query: 487 SVSSSSSSSSSGHKRHKKHKRNRSESSRSSRRHSSRASSNQIDQNRKDECYPVPANTSAS 546
+ ++ +R R + +++ RHS R + ++ + E
Sbjct: 173 RNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETET---------- 222
Query: 547 FLNHKQEVEKLLGKQDRLQYEKTQIKEKDRCPLSSSSLEIPDDFGGRSEDPRDFYNSYKT 606
K++ ++ +Q + + E+ + E++R +S E D E RD +
Sbjct: 223 --ERKRQTDRERDRQRKTEREREKQAERER----ASERETERDKERERERDRDRDRDRRQ 276
Query: 607 QAGSSKTEKPYKS----------------ERHFSSRRNSSDSFCRNSEDKIYGYRRFEKD 650
+ +T++ + ER RN R E + R E+D
Sbjct: 277 KERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERD 336
Query: 651 IEGRKEHYRRWEPGSVRHSTSPASSEYSWKSVEKYKKYAHSGSRDFSRHEQRYRLNTNQG 710
E +E R+ + R E+ ++ G R R +R R Q
Sbjct: 337 REKERERKRKRQTEMDR---------------ERNRQTGREGRRQAERERERERERDRQS 381
Query: 711 EYEREDNYGEDIKTEVPEEDALSSKE 736
ERE+ + + E + + K+
Sbjct: 382 AREREERERDRDRDRQKERERQTEKD 407
Score = 30.4 bits (67), Expect = 6.5
Identities = 19/96 (19%), Positives = 41/96 (42%), Gaps = 1/96 (1%)
Query: 438 KQAEKEEKQKTKKIETSAEKLRKLLKEEKRLKKKRRKSTSSSSVSSADESVSSSSSSSSS 497
+QAE+E +++ ++ SA + + ++ R ++K R+ + E+
Sbjct: 365 RQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDR 424
Query: 498 GHKRHKKHKRNRSESSRSSRRHSSRASSNQIDQNRK 533
+R ++ R R E + R R + Q + RK
Sbjct: 425 ESERGRERGRER-EKQKGRERDRERQTDRQAGRQRK 459
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 54.3 bits (129), Expect = 4e-07
Identities = 37/186 (19%), Positives = 78/186 (41%), Gaps = 6/186 (3%)
Query: 437 EKQAEKEEKQKTKKIETSAEKLRKLLKEEKRLKKKRRKSTSSSSVSSADESVSSSSSSSS 496
E + K+ +++ +I + E+ RK +EE+R +++RK+ + + DE + S
Sbjct: 441 EDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPS 500
Query: 497 SGHKRHKKHKRNRS-----ESSRSSRRHSSRASSNQIDQNRKDECYPVPANTSASFLNHK 551
R ++ ++ R E + R R + Q ++ E K
Sbjct: 501 PEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERK 560
Query: 552 QEVEKLLGKQDRLQYEKTQIKEKDR-CPLSSSSLEIPDDFGGRSEDPRDFYNSYKTQAGS 610
QE EK L +Q + E ++KE+++ C L ++ + R + +++
Sbjct: 561 QEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSC 620
Query: 611 SKTEKP 616
+K E+P
Sbjct: 621 NKEEEP 626
Score = 40.0 bits (92), Expect = 0.008
Identities = 42/207 (20%), Positives = 86/207 (41%), Gaps = 16/207 (7%)
Query: 368 LENCPTHRNARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALDETFKDAEDALQKLHK 427
LE P+ R+ + ER +LE+E++ + K E K+ E +K +
Sbjct: 495 LEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQRE 554
Query: 428 YMQKSLELREKQAEKEEKQKTKKIETSAEKLRKLLKEEKRLKKKRRKSTSSSSVSSADES 487
++ + +EK+ E++ K+K K+++ E+ ++ E++R K + + ++ E
Sbjct: 555 MEKERKQEKEKELERQ-KEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEK 613
Query: 488 VSSSSSSSSSGHKRHKKHKRNRSESSRSSRRHSSRASSNQIDQNRKDECYPVPANTSASF 547
S +S + + NRSE + H + S P PA S F
Sbjct: 614 QESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGS---------QPRPAVLSGYF 664
Query: 548 LNHKQEVEKLLGKQDRLQYEKTQIKEK 574
++ + R Q ++ Q+K++
Sbjct: 665 KQFQKSL------PPRFQRQQEQMKQQ 685
Score = 34.7 bits (78), Expect = 0.34
Identities = 38/187 (20%), Positives = 75/187 (40%), Gaps = 21/187 (11%)
Query: 387 ERGGQLEEEEKFLNAESYYK---KALALDETFKDAEDALQKLHKYMQKSLELREKQAEKE 443
E ++EE+ K AE + K L++ E ++ K ++ EL ++Q ++
Sbjct: 468 EEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQER 527
Query: 444 EKQKTKKIETSAEKLRKLLKEEKRLK--KKRRKSTSSSSVSSADESVSSSSSSSSSGHKR 501
EK++ K E EK ++L KE+++ + +K RK + K
Sbjct: 528 EKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELER---------------QKE 572
Query: 502 HKKHKRNRSESSRSSRRHSSRASSNQIDQNRKDECYPVPANTSASFLNHKQEVEKLLGKQ 561
+K + E + R + + R+ P+ + +K+E E + +Q
Sbjct: 573 KEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEE-EPVFTRQ 631
Query: 562 DRLQYEK 568
D + EK
Sbjct: 632 DSNRSEK 638
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 53.9 bits (128), Expect = 5e-07
Identities = 71/336 (21%), Positives = 127/336 (37%), Gaps = 56/336 (16%)
Query: 425 LHKYMQKSLELREKQAEKEEKQKTKKIETSAEKLRKLLKEEKRLKKKRRKSTSSSSVSSA 484
+ K + + ++ R ++ +K+ K+ ++I+ E+ R + +R RR S S S
Sbjct: 225 VQKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRS--RSPRRSLSPRRSPRRSRSRSHH 282
Query: 485 DESVSSSSSSSS------------SGHKRHKKHKRNRS-------ESSRSSRRHSSRASS 525
E SSS +R K+ +R+RS SRS RH SR+ S
Sbjct: 283 REGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRS 342
Query: 526 NQIDQNRKDECYPVPANTSASFLNHKQEVEKLLGKQDRLQY--------EKTQIKEKDRC 577
+R+D + ++E E G++ Y EK + + ++R
Sbjct: 343 RDRKGDRRDR-------------DREREKENERGRRRDRDYDKERGNEREKERERSRERS 389
Query: 578 PLSSSSLEIPDDFGGRSEDPRDFYNSYKTQAGSSKTEKPYKSERHFSSRRNSSDSFCRN- 636
S E+ + +D R + + K + ER SR S ++ R+
Sbjct: 390 KEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSR 449
Query: 637 -----------SEDKIYGYRRFEKDIEGRKEHYRRWEPGSVRHSTSPASSEYSWKSVEKY 685
+E K +R +GR + + + HS S S +S E+
Sbjct: 450 SRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKRE--HSPSKEKSRKRSRSKERS 507
Query: 686 KKYAHSGSRDFSRHEQRYRLNTNQGEYEREDNYGED 721
K HS S+D S R R + + E + + + +D
Sbjct: 508 HKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNKD 543
Score = 45.8 bits (107), Expect = 1e-04
Identities = 37/166 (22%), Positives = 68/166 (40%), Gaps = 18/166 (10%)
Query: 387 ERGGQLEEEEKFLNAESYYKKALALDETFKDAEDALQKLHKYMQKSLELREKQAEKEEKQ 446
ERG + E+E + S +++ E K ED + H+ ++ + +K + ++
Sbjct: 373 ERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRE 432
Query: 447 KTKKIET------------SAEKLRKLLKEEKRLKKKRRKSTSSSSVSSADESVS----- 489
+ + + S EK K E K KR +S S S ++S
Sbjct: 433 RKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSP 492
Query: 490 SSSSSSSSGHKRHKKHKRNRSESSRSSRRHSSRASSNQIDQNRKDE 535
S S + + HKR+ S+S S +H R S + I+Q +++
Sbjct: 493 SKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQS-IEQESQEK 537
Score = 37.0 bits (84), Expect = 0.069
Identities = 51/245 (20%), Positives = 104/245 (42%), Gaps = 20/245 (8%)
Query: 391 QLEEEEKFLNAESYYKKALALDETFKDAEDALQKLHKYMQKSLEL------REKQAEKE- 443
+LE E K E +++ ++D + ++ H+ +S + R+++ EKE
Sbjct: 303 RLEREAK--EREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKEN 360
Query: 444 EKQKTKKIETSAEKLRKLLKEEKRLKKKRRKSTSSSSVSSA---DESVSSSSSSSSSGHK 500
E+ + + + E+ + KE +R +++ ++ S V ++ K
Sbjct: 361 ERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSK 420
Query: 501 RHKKHKRNRSESSRSSRRHSSRASSNQIDQNRKDECYPVPANTSASFLNHKQEVEKLLGK 560
+ KKH R+RS + R SR ++ + ++R E N S N K+ G+
Sbjct: 421 KEKKHSRSRSRERKHRSRSRSR-NAGKRSRSRSKEKSSKHKNESKEKSN-KRSRSGSQGR 478
Query: 561 QDRLQYEK----TQIKEKDRCPLSSSSLEIPDDFGGRSEDPRDFYNSYKTQAGSSKT-EK 615
D ++ K + KEK R S D S+D D ++ ++Q+ ++ EK
Sbjct: 479 TDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSD-SKDQSDKHDRRRSQSIEQESQEK 537
Query: 616 PYKSE 620
+K++
Sbjct: 538 QHKNK 542
>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
Length = 717
Score = 53.9 bits (128), Expect = 5e-07
Identities = 52/179 (29%), Positives = 81/179 (45%), Gaps = 17/179 (9%)
Query: 443 EEKQKTKKIETSAEKLRKLLKEEKRLKKKRRKSTSSSSVSSADESVSSSSSSSSSGHKRH 502
E K KTK S + R + K R +S+SSSS SS+ S SSS SSSSSG
Sbjct: 551 ESKSKTKTRSRSRGRARN------KTSKSRSRSSSSSSSSSSSTS-SSSGSSSSSGSSSS 603
Query: 503 KKHKRNRSESSRSSRRHSSRASSNQIDQNRKDECYPVPANTSASFLNHKQEVEKLLGKQD 562
+ + S +S SS R SS ++S+ + + H++ V++ ++D
Sbjct: 604 RSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSR-----GRGHNRDRKHRRSVDR--KRRD 656
Query: 563 RLQYEKTQIKEKDRCPLSSSSLEIPDDFGGRSEDPRDFYNSYKTQAGSSKTEKPYKSER 621
E++ K SS + D RS+ R S ++ SS++E+ KS+R
Sbjct: 657 TSGLERSHKSSKGG---SSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDR 712
Score = 38.9 bits (89), Expect = 0.018
Identities = 33/119 (27%), Positives = 51/119 (42%), Gaps = 19/119 (15%)
Query: 436 REKQAEKEEKQKTKKIETSAEKLRKLLKEEKRLKKKRRKSTSSSSVSSADESVSSSSSSS 495
R + K K +++ +S+ S+ SSS SS+ S SSS SS
Sbjct: 563 RGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSS 622
Query: 496 SS--------------GHKRHKKHKRN----RSESSRSSRRH-SSRASSNQIDQNRKDE 535
SS GH R +KH+R+ R ++S R H SS+ S++ + KD+
Sbjct: 623 SSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDK 681
Score = 33.1 bits (74), Expect = 1.0
Identities = 19/71 (26%), Positives = 31/71 (43%)
Query: 463 KEEKRLKKKRRKSTSSSSVSSADESVSSSSSSSSSGHKRHKKHKRNRSESSRSSRRHSSR 522
K + + +KRR ++ + + SS + S KR+ SESSRS +R S
Sbjct: 645 KHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRS 704
Query: 523 ASSNQIDQNRK 533
+ D+ K
Sbjct: 705 ERDRKSDRKDK 715
Score = 31.2 bits (69), Expect = 3.8
Identities = 18/54 (33%), Positives = 33/54 (61%), Gaps = 4/54 (7%)
Query: 425 LHKYMQKSLELREKQAEKEEKQKTKKIETSAEKLRKLLKEEKR--LKKKRRKST 476
L K+ Q+S E+Q ++E ++ K+E AE+ RK ++ E+R +++R K T
Sbjct: 153 LQKFKQESTVATERQKRRQEIEQ--KLEVQAEEERKQVENERRELFEERRAKQT 204
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 53.9 bits (128), Expect = 5e-07
Identities = 73/309 (23%), Positives = 119/309 (38%), Gaps = 50/309 (16%)
Query: 434 ELREKQAEKEEKQKTKKIETSAEKLRKLLKEEKRLKKKRRKSTSSSSVSSADESVSSSSS 493
E ++ EKE+K K K + +R+ +++ + K K +K S S S S
Sbjct: 414 ESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKS--------RSKSK 465
Query: 494 SSSSGHKRHKKHKRNRSESSRSSRRHSSRASSNQIDQNRKDECYPVPANTSASFLNHKQE 553
S +R KH NR+E R R R N ++ ++ + S S K++
Sbjct: 466 EKSKSKERDSKH--NRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRS----KEK 519
Query: 554 VEKLLGKQDRLQYEKTQIKEKDRCPLSSSSLEIPDDFGGRSEDPRDFYNSYKTQAGSSKT 613
++L K + +++ ++ KEKDR S S E G S YNS + S+
Sbjct: 520 SKQLESKSN--EHDHSKSKEKDR-RAQSRSRECDITKGKHS------YNSRTRERSRSRD 570
Query: 614 EKPYKSERHFSSRRNSSDSFCRNSEDKIYGYRRFEKDIEGR-KEHYRRWEPGSVRHSTSP 672
R SR + D R+ + + YR E GR + RR PG
Sbjct: 571 R-----SRRVRSRTHDRD---RSRSKEYHRYREQEYRRRGRSRSRERRTPPG-------- 614
Query: 673 ASSEYSWKSVEKYKKYAHSGSRDFSRHEQRYRLNTNQGEYEREDNYGEDIKTEVPEEDAL 732
+S K ++ SR R E + R N+ +Y +++ K E +
Sbjct: 615 -------RSRSKDRRRRRRDSRSSEREESQSR---NKDKYRNQESKSSHRKENSESEKRM 664
Query: 733 SSKEHSESS 741
SK +S
Sbjct: 665 YSKSRDHNS 673
Score = 53.5 bits (127), Expect = 7e-07
Identities = 89/404 (22%), Positives = 169/404 (41%), Gaps = 46/404 (11%)
Query: 382 CQTLVERGGQLEEEEKFLNAESYYKKALALDETFKDAEDALQKLHKYMQKSLELREKQAE 441
C L+ + +EE+K + S + + ++ D+ Q S + + ++
Sbjct: 174 CGELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDS-----------QSSSDSSDSESA 222
Query: 442 KEEKQKTKKIETSAEKLRKLLKEEKRLKKKRRKSTSSSSVSSADESVSSSSSSSSSGHKR 501
EEK K +K +K RK ++ K+ KKKR+KS S+S S E++ + S+ +
Sbjct: 223 TEEKSKKRK-----KKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVR-PEE 276
Query: 502 HKKHKRNRSESSRSSRRHSSRASSNQIDQNRKDECYPVPANTSASF---LNHKQEVEKLL 558
NR +S + + N+ ++ R+ EC P P + AS+ L + K+
Sbjct: 277 IPPIPENRFLMRKSPPKADEKERKNR-ERERERECNP-PNSQPASYQRRLLVTRSGRKIK 334
Query: 559 GKQDRLQYEKTQIKEKDRCPLSSS----SLEIPDDFGGRSEDPRDFYNSYKTQAGSSKTE 614
G+ R ++ + +DR S + E+ R + K++ K
Sbjct: 335 GRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKEN 394
Query: 615 K--PYK-SERHFSSRRNSSDSFCRNSEDKIYGYRRFEKDIEGRKEHYRRWEPGSVRHSTS 671
+ P + ER + RN S+S R +E EK + K+H + +R + S
Sbjct: 395 QRSPVRVKERKITDHRNVSESPNRKNEK--------EKKV---KDHKSNSKERDIRRN-S 442
Query: 672 PASSEYSWKSVEKYKKYAHSGSRDFSRHEQR-YRLNTNQGEYEREDNYGEDIKTEVPEED 730
+Y K ++ K + S S++ S+ ++R + N N+ + R + G D + +E
Sbjct: 443 EKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEK 502
Query: 731 ALSSK----EHSESSVKKNLPQNLLNIFNQIAEFEKEKGNKSKN 770
SK E S S K ++ N + EK++ +S++
Sbjct: 503 QSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRS 546
Score = 50.4 bits (119), Expect = 6e-06
Identities = 72/346 (20%), Positives = 134/346 (38%), Gaps = 43/346 (12%)
Query: 416 KDAEDALQKLHKYMQKSLELREKQAEKEEKQKTKKIETSAEKLRKLLKEEKRLK------ 469
K+ ++ K HK K ++R + +EK++K K K + + K R KE+ + K
Sbjct: 419 KNEKEKKVKDHKSNSKERDIR-RNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKH 477
Query: 470 -----KKRRKSTSSSSVSSADESVSSSSSSSSSGHKRHKKHKRNRSESSRSSRRHSSRAS 524
K+ R + + E S S + K K + ES + HS
Sbjct: 478 NRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKE 537
Query: 525 SNQIDQNRKDECYPVPANTSASFLNHKQEVEKLLGKQDRLQYEKTQIKEKDRCPLSSSSL 584
++ Q+R EC + + ++ + +DR + +++ ++DR
Sbjct: 538 KDRRAQSRSREC-----DITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHR 592
Query: 585 EIPDDFGGRSEDPRDFYNSYKTQAGSSKTEKPYKSERHFSSRRNSSDSFCRNSEDKIYGY 644
++ R R +T G S+++ + R SR + + ++DK Y
Sbjct: 593 YREQEYRRRG---RSRSRERRTPPGRSRSKD--RRRRRRDSRSSEREESQSRNKDK---Y 644
Query: 645 RRFEKDIEGRKEH---YRRWEPGSVRHSTSPASSEYSWKSVEKYKKYAHSGSRDFSRHEQ 701
R E RKE+ +R S H++S S E K A FS+ +Q
Sbjct: 645 RNQESKSSHRKENSESEKRMYSKSRDHNSSNNSRE----------KKADRDQSPFSKIKQ 694
Query: 702 RYRLNTNQGEY--EREDNYGEDIKTEVPEEDALSSKEHSESSVKKN 745
+ N + +ED E I++ V +E+ S + ++ +KN
Sbjct: 695 SSQDNELKSSMLKNKED---EKIRSSVEKENQKSKGQENDHVHEKN 737
>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
Length = 2663
Score = 53.1 bits (126), Expect = 9e-07
Identities = 106/492 (21%), Positives = 172/492 (34%), Gaps = 86/492 (17%)
Query: 355 GSLNKAIEDFELALENCPTHRNARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALDET 414
G +K+ DF LE H AR+ ++ G +E ++ E Y +K+ D++
Sbjct: 984 GFKDKSDGDFGKGLEPWERHHPAREK-----EKKDGPDKERKEKTKPERYKEKSSDKDKS 1038
Query: 415 FKDAEDALQK---LHKYMQKSLELREKQAEKEEKQKTKK--IETSAEKLRKLL------- 462
K + QK K ++ + +EK + K K +K ++ EK K
Sbjct: 1039 EKSILEKCQKDKEFDKCFKEKKDTKEKHKDTHGKDKERKASLDQGKEKKEKAFPGIISED 1098
Query: 463 -KEEKRLKKKRRKSTSSSSVSSADESVSSSSSSSSSGHK-------------RHKKHKRN 508
E+K KK + KS + + + DES S SG K + K+ R
Sbjct: 1099 FSEKKDDKKGKEKSWYIADIFT-DESEDDRDSCMGSGFKMGEASDLPRTDGLQEKEEGRE 1157
Query: 509 RSESSR----SSRRHSSRASSNQIDQNRKDECYPVPANTSAS--FLNHKQE-----VEKL 557
S R S ++H R + RKD F HK++ EK
Sbjct: 1158 AYASDRHRKSSDKQHPERQKDKEPRDRRKDRGAADAGRDKKEKVFEKHKEKKDKESTEKY 1217
Query: 558 LGKQDRLQYEKTQIKE-KDRCPLSSSSLEIPDDFG-------GRSEDPRDFYNSYKTQAG 609
++DR + TQ K+ K + P + +D E ++ +S A
Sbjct: 1218 KDRKDRASVDSTQDKKNKQKLPEKAEKKHAAEDKAKSKHKEKSDKEHSKERKSSRSADAE 1277
Query: 610 SSKTEK-------PYKSERHFSSRRNSSDSFC-RNSEDKIYGYRRF--------EKDIEG 653
S EK Y+ + + SSDSF R E + + +K E
Sbjct: 1278 KSLLEKLEEEALHEYREDSNDKISEVSSDSFTDRGQEPGLTAFLEVSFTEPPGDDKPRES 1337
Query: 654 RKEHYRRWEPGSVRHSTSPASSEYSWKSVEKYKKYAHSGSRDFSRHEQRYRLNTNQGEYE 713
+ E RHS+S + + + +K K D+ R + G+YE
Sbjct: 1338 ACLPEKLKEKERHRHSSSSSKKSHDRERAKKEKAEKKEKGEDYKEGGSR----KDSGQYE 1393
Query: 714 RE----DNYGEDIKTEVPEEDAL-----------SSKEHSESSVKKNLPQNLLNIFNQIA 758
++ D YG + ED L K SE K + + L +
Sbjct: 1394 KDFLEADAYGVSYNMKADIEDELDKTIELFSTEKKDKNDSEREPSKKIEKELKPYGSSAI 1453
Query: 759 EFEKEKGNKSKN 770
KEK + K+
Sbjct: 1454 NILKEKKKREKH 1465
Score = 38.9 bits (89), Expect = 0.018
Identities = 85/436 (19%), Positives = 169/436 (38%), Gaps = 56/436 (12%)
Query: 358 NKAIEDFELALENCPTHRNARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALDE-TFK 416
+K D + LEN + N K L ++EEK + K+ L DE + K
Sbjct: 664 SKQKSDKAILLENDLSTENKLK----VLKHDRDHFKKEEKLSKMKLEEKEWLFKDEKSLK 719
Query: 417 DAEDALQKLHKYMQKSLELREKQAEKEEKQKTKKIETSAEKLRKLLKEEKRLKKKRRKST 476
+D +K + +S + ++ K EK+++ K ++ E+ +L KEE++ K K R S
Sbjct: 720 RIKDT----NKDISRSFREEKDRSNKAEKERSLKEKSPKEEKLRLYKEERKKKSKDRPSK 775
Query: 477 SSSSVSSADESVSSSSSSSSSGHK-RHKKHKRNRSESSRSSRRHSSRASSNQ-----IDQ 530
++ +S K + KK K R +S+ + ++ N+ +
Sbjct: 776 LEKKNDLKEDKISKEKEKIFKEDKEKLKKEKVYREDSAFDEYCNKNQFLENEDTKFSLSD 835
Query: 531 NRKDECYPVPANTSASFLNHKQEVEKLLGKQDR---------LQYEKTQIKEKDRCPLSS 581
+++D + +++S F + +D L+ K KE+ R +
Sbjct: 836 DQRDRWFSDLSDSSFDFKGEDSWDSPVTDYRDMKSDSVAKLILETVKEDSKERRRDSRAR 895
Query: 582 SSLEIPDDFGGRSEDPRDFYN----SYKTQAGSSKTEKPYKSERHFSSRRNSSDSFCRNS 637
+ + F + + RD+ + K Q K+ Y SE+ +R S R+
Sbjct: 896 EKRDYREPFFRKKD--RDYLDKNSEKRKEQTEKHKSVPGYLSEK--DKKRRESAEAGRDR 951
Query: 638 EDKIYGYRRFEKDIEGRKEHYRRWEPGSVRHSTSPASSEYSWKSVEKYKKYAHSGSRDFS 697
+D + + +D + E R E E +K DF
Sbjct: 952 KDALESCKE-RRDGRAKPEEAHREE-------LKECGCESGFKD---------KSDGDFG 994
Query: 698 RHEQRYRLNTNQGEYEREDNYGEDIKTEVPEE---DALSSKEHSESSVKKNLPQNLLNIF 754
+ + + + E E++D ++ K + E + S K+ SE S+ + ++ F
Sbjct: 995 KGLEPWERHHPAREKEKKDGPDKERKEKTKPERYKEKSSDKDKSEKSILEKCQKD--KEF 1052
Query: 755 NQIAEFEKEKGNKSKN 770
++ F+++K K K+
Sbjct: 1053 DKC--FKEKKDTKEKH 1066
Score = 35.0 bits (79), Expect = 0.26
Identities = 62/292 (21%), Positives = 114/292 (39%), Gaps = 21/292 (7%)
Query: 431 KSLELREKQAEKEEKQKTKKIETSAEKLRKLLKEEKRLKKKRRKSTSSSSVSSADESVSS 490
K ++ EK EK++K+ T+K + ++ + + + KK ++K + A E +
Sbjct: 1197 KKEKVFEKHKEKKDKESTEKYK---DRKDRASVDSTQDKKNKQKLPEKAEKKHAAEDKAK 1253
Query: 491 SSSSSSSGHKRHKKHKRNRSESSRSSRRHSSRASSNQIDQNRKDECYPVPANTSASFLNH 550
S S + K+ K +RS + S + + + R+D + +S SF +
Sbjct: 1254 SKHKEKSDKEHSKERKSSRSADAEKSL--LEKLEEEALHEYREDSNDKISEVSSDSFTDR 1311
Query: 551 KQEVEKLLGKQDRLQYEKTQIKEKDRCPLSSSSLEIPDDFGGRSEDPRDFYNSYKT---- 606
QE G L+ T+ D+ P S+ L P+ + +S K+
Sbjct: 1312 GQEP----GLTAFLEVSFTEPPGDDK-PRESACL--PEKLKEKERHRHSSSSSKKSHDRE 1364
Query: 607 QAGSSKTEKPYKSE--RHFSSRRNSSDSFCRNSEDKIYGYR-RFEKDIEGRKEHYRRWEP 663
+A K EK K E + SR++S E YG + DIE + + E
Sbjct: 1365 RAKKEKAEKKEKGEDYKEGGSRKDSGQYEKDFLEADAYGVSYNMKADIEDELD--KTIEL 1422
Query: 664 GSVRHSTSPASSEYSWKSVEKYKKYAHSGSRDFSRHEQRYRLNTNQGEYERE 715
S S K +EK K S + + + +++ + + E+E
Sbjct: 1423 FSTEKKDKNDSEREPSKKIEKELKPYGSSAINILKEKKKREKHREKWRDEKE 1474
Score = 34.3 bits (77), Expect = 0.45
Identities = 68/342 (19%), Positives = 124/342 (36%), Gaps = 47/342 (13%)
Query: 460 KLLKEEKRLKKKRRKSTSSSSV---SSADESVSSSSSSSSSGHKRHKKHKRNRSE----- 511
K KE+ ++KKKR+K T V +D+ SS S S SS + S
Sbjct: 446 KQQKEKNKVKKKRKKETKGREVRFGKRSDKFCSSESESESSESGEDDRDSLGSSGCLKGS 505
Query: 512 ----------SSRSSRRHSSRASSNQIDQNRKDECYPVPANTSASFLNHKQEVEKLLGKQ 561
SS S+ SS SS QN P++T + + + K +
Sbjct: 506 PLVLKDPSLFSSLSASSTSSHGSSAAQKQN--------PSHTDQHTKHWRTDNWKTISSP 557
Query: 562 DRLQYEKTQIKEKDRCPLSSSSLEIPDDFGGRSEDPRDFYNSYKTQAGSSKTEKPYKSER 621
E + + + R L+S S + S P ++ +A S+ + P+ S
Sbjct: 558 --AWSEVSSLSDSTRTRLTSESDYSSEGSSVESLKPVRKRQEHRKRASLSEKKSPFLSSA 615
Query: 622 HFSSRRNSSDSFCRNSEDKIYGYRRFEK-----DIEGRKEHYRRWEPGSVRHSTSPASSE 676
+ + + + ++ EK E + + + S + S E
Sbjct: 616 EGAVPKLDKEGKVVKKHKTKHKHKNKEKGQCSISQELKLKSFTYEYEDSKQKSDKAILLE 675
Query: 677 YSWKSVEKYKKYAHSGSRDFSRHEQRYRLNTNQGEY--------EREDNYGEDIKTEVPE 728
+ K K H F + E+ ++ + E+ +R + +DI E
Sbjct: 676 NDLSTENKLKVLKHDRDH-FKKEEKLSKMKLEEKEWLFKDEKSLKRIKDTNKDISRSFRE 734
Query: 729 EDALSSKEHSESSVKKNLPQNLLNIFNQIAEFEKEKGNKSKN 770
E S+K E S+K+ P+ ++ +++E+ KSK+
Sbjct: 735 EKDRSNKAEKERSLKEKSPKE-----EKLRLYKEERKKKSKD 771
Score = 33.1 bits (74), Expect = 1.0
Identities = 49/225 (21%), Positives = 85/225 (37%), Gaps = 25/225 (11%)
Query: 453 TSAEKLRKLLKEEKRLKKKRRKSTSSSSVSSADESVSSSSSSSSSGHKRHKKHKRNRSES 512
+S E L+ + K ++ K+ S +SSA+ +V K KHK E
Sbjct: 584 SSVESLKPVRKRQEHRKRASLSEKKSPFLSSAEGAVPKLDKEGKVVKKHKTKHKHKNKEK 643
Query: 513 SRSSRRHSSRASS----NQIDQNRKDECYPVPANTSA----SFLNHKQEVEKLLGKQDRL 564
+ S + S + + + D+ + + S L H ++ K K ++
Sbjct: 644 GQCSISQELKLKSFTYEYEDSKQKSDKAILLENDLSTENKLKVLKHDRDHFKKEEKLSKM 703
Query: 565 QYEKTQIKEKDRCPLS---------SSSLEIPDDFGGRSEDPRDFYNSYKTQAGSSKTEK 615
+ E+ + KD L S S D ++E R S K ++ + +
Sbjct: 704 KLEEKEWLFKDEKSLKRIKDTNKDISRSFREEKDRSNKAEKER----SLKEKSPKEEKLR 759
Query: 616 PYKSERHFSSRRNSSDSFCRN--SEDKIYGYRR--FEKDIEGRKE 656
YK ER S+ S +N EDKI + F++D E K+
Sbjct: 760 LYKEERKKKSKDRPSKLEKKNDLKEDKISKEKEKIFKEDKEKLKK 804
Score = 31.2 bits (69), Expect = 3.8
Identities = 58/267 (21%), Positives = 101/267 (37%), Gaps = 35/267 (13%)
Query: 390 GQLEEEEKFLNAESYYKKALALDET----FKDAEDALQKLHKYMQKSLELREKQAEKEEK 445
G E K + ++K +L E AE A+ KL +K+ + +K
Sbjct: 583 GSSVESLKPVRKRQEHRKRASLSEKKSPFLSSAEGAVPKL-----------DKEGKVVKK 631
Query: 446 QKTKKIETSAEKLRKLLKEEKRLKKKRRKSTSSSSVSSADESVSSSSSSSSSGHKRHKKH 505
KTK + EK + + +E +LK + S S D+++ + S+ + KH
Sbjct: 632 HKTKHKHKNKEKGQCSISQELKLKSFTYEYEDSKQKS--DKAILLENDLSTENKLKVLKH 689
Query: 506 KRNR-SESSRSSRRHSSRASSNQIDQNRKDECYPVPANTSASF-----LNHKQEVEKLLG 559
R+ + + S+ D+ + S SF ++K E E+ L
Sbjct: 690 DRDHFKKEEKLSKMKLEEKEWLFKDEKSLKRIKDTNKDISRSFREEKDRSNKAEKERSLK 749
Query: 560 KQD------RLQYEKTQIKEKDRCPLSSSSLEIPDDFGGRSEDPRDFYNSYKTQAGSSKT 613
++ RL E+ + K KDR S LE +D + ++ +K K
Sbjct: 750 EKSPKEEKLRLYKEERKKKSKDR----PSKLEKKNDL-KEDKISKEKEKIFKEDKEKLKK 804
Query: 614 EKPYKSERHFSSRRNSSDSFCRNSEDK 640
EK Y+ + F N + F N + K
Sbjct: 805 EKVYREDSAFDEYCN-KNQFLENEDTK 830
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 53.1 bits (126), Expect = 9e-07
Identities = 68/311 (21%), Positives = 115/311 (36%), Gaps = 23/311 (7%)
Query: 436 REKQAEKEEKQKTKKIETSAEKLRKLLKEEKRLKKKRRKSTSSSSVSSADESVSSSSSSS 495
++K+ +K K K K + EK K EK K+K+RK + S + AD
Sbjct: 677 KKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPP 736
Query: 496 SSGHKRHKKHKRNRSESSRSSRRHSSRASSNQIDQNRKDECYPVPANTSASFLNHKQEVE 555
SG + +R + S+ + SS +KDE ++ HK E+
Sbjct: 737 GSGSPAPPRRRRRAQDDSQRRSLPAEEGSS-----GKKDEGGGGSSSQDHGGRKHKGELP 791
Query: 556 KLLGKQDRLQYEKTQIKEKDRCPLSSSSLEIPDDFGGR--SEDPRDFYNSYKTQ-AGSSK 612
R K + R SS + D R + P + + + +GS
Sbjct: 792 P--SSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEH 849
Query: 613 TEKPYKSER----HFSSRRNSSDSFCRNSEDKIYGYRRFEKDIEGRKEHYRRWEPGSVRH 668
+ +S R H SSRR+ S S +S+ Y +R D + Y + S RH
Sbjct: 850 SRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSD-----DSYSDYSDRSRRH 904
Query: 669 STSPASSEYSWKSVEKYKKYAHSGSRDFSRHEQRYRLNTNQGEYEREDNYGEDIKTEVPE 728
S S+ S + K++ H +S + Y L+ +Q + E ++
Sbjct: 905 SKRSHDSDDSDYASSKHRSKRHK----YSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRS 960
Query: 729 EDALSSKEHSE 739
+ S+ S+
Sbjct: 961 RSSSCSRSRSK 971
Score = 50.1 bits (118), Expect = 8e-06
Identities = 68/311 (21%), Positives = 121/311 (38%), Gaps = 33/311 (10%)
Query: 443 EEKQKTKKIETSAEKLRKLLKEEKRLKKKRRKSTSSSSVSSADESVSSSSSSSSSGHKRH 502
E + + + + E+ K + +K KKK +KS+ AD SS + S K+
Sbjct: 654 ETEDTGRSLPSKKERSGKSHRHKK--KKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKR 711
Query: 503 KKHKRNRSESSRSSRRHSSRASSNQIDQNRKDECYPVPANTSASFLNHKQEVEKLLGKQD 562
KK KR +++SS + D R + P P + + ++ + ++
Sbjct: 712 KKRKRKKNKSSAPA------------DSERGPK--PEPPGSGSPAPPRRRRRAQDDSQRR 757
Query: 563 RLQYEKTQIKEKDRCPLSSSSLEIPDDFGGRSEDPRDFYNSYKTQAGSSKTEKPYKSERH 622
L E+ +KD SSS D GGR +S + +AG+ ++ + +
Sbjct: 758 SLPAEEGSSGKKDEGGGGSSS----QDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQP 813
Query: 623 FSSRRNSSDSFCRNSEDKIYG-YRRFEKDIEGRKEHYRRWEPGSVRH-----------ST 670
S +S D+ K Y E++ + EH R RH S+
Sbjct: 814 SSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSS 873
Query: 671 SPASSEYSWKSVEK-YKKYAHSGSRDFSRHEQRYRLNTNQGEYEREDNYGEDIKTEVPEE 729
S ASS+ S S ++ Y ++S D SR + +++ +Y + + K ++
Sbjct: 874 SDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDD 933
Query: 730 DALSSKEHSES 740
D S S S
Sbjct: 934 DYSLSCSQSRS 944
Score = 46.6 bits (109), Expect = 9e-05
Identities = 68/270 (25%), Positives = 113/270 (41%), Gaps = 33/270 (12%)
Query: 416 KDAEDALQKLHKYMQKSLELREKQAEKEEKQKTKKIETSAEKLRKLLKEEKRLKKKRRKS 475
+D++DA H+ QKS Q +EE+++ E S + R + + R+S
Sbjct: 818 EDSDDASS--HRLHQKS----PSQYSEEEEEEDSGSEHSRSRSRSGRRHSSH--RSSRRS 869
Query: 476 TSSSSVSSADESVSS--------SSSSSSSGHKRHKKHKRNRSESSRSSRRHSSRASSNQ 527
SSSS +S+D+S S S S S +RH K + +S +S +H S+
Sbjct: 870 YSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHK-- 927
Query: 528 IDQNRKDECYPVPANTSAS-FLNHKQEVEKLLGKQDRLQYEKTQIKEKDRCPLSSSSLEI 586
+ D+ Y + + S S +H +E + G+ +++ K + R + S
Sbjct: 928 --YSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRS 985
Query: 587 PDDFGGRSEDPRDFYNSYKTQAGSSKTEKPYKS--ERHFSSRRNSSDSFCRNSEDKIYGY 644
RS R S ++GS K ++S ERH S RR+ S S+ Y +
Sbjct: 986 RSYSRDRSRSTR----SPSQRSGSRKRSWGHESPEERH-SGRRDFIRSKIYRSQSPHY-F 1039
Query: 645 RRFEKDIEGRKEHYRRWEPGSVRHSTSPAS 674
R + G+K+ R G +T P S
Sbjct: 1040 RSGRGEGPGKKDDGR----GDDSKATGPPS 1065
>gi|8923106 zinc finger, CCHC domain containing 10 [Homo sapiens]
Length = 170
Score = 53.1 bits (126), Expect = 9e-07
Identities = 43/137 (31%), Positives = 58/137 (42%), Gaps = 16/137 (11%)
Query: 424 KLHKYMQKSLELREKQAEKEEKQKTKKIETSAEKLRKLLKE----------------EKR 467
K H QK LE E K+K + +L+K LKE E++
Sbjct: 18 KQHVRCQKCLEFGHWTYECTGKRKYLHRPSRTAELKKALKEKENRLLLQQSIGETNVERK 77
Query: 468 LKKKRRKSTSSSSVSSADESVSSSSSSSSSGHKRHKKHKRNRSESSRSSRRHSSRASSNQ 527
KKKR KS +SSS SS+D S S SSS S + ESS SS +S +S+
Sbjct: 78 AKKKRSKSVTSSSSSSSDSSASDSSSESEETSTSSSSEDSDTDESSSSSSSSASSTTSSS 137
Query: 528 IDQNRKDECYPVPANTS 544
+ D ++TS
Sbjct: 138 SSDSDSDSSSSSSSSTS 154
Score = 45.8 bits (107), Expect = 1e-04
Identities = 47/162 (29%), Positives = 72/162 (44%), Gaps = 14/162 (8%)
Query: 376 NARKYLCQTLVERGGQLEE---EEKFLNAESYYKKALALDETFKDAEDALQKLHKYMQKS 432
N + CQ +E G E + K+L+ S + L + K+ E+ L +Q+S
Sbjct: 17 NKQHVRCQKCLEFGHWTYECTGKRKYLHRPS---RTAELKKALKEKENRL-----LLQQS 68
Query: 433 LELREKQAEKEEKQKTKKIETSAEKLRKLLKEEKRLKKKRRKSTSSSSVSS-ADESVSSS 491
+ E E++ K+K K TS+ + STSSSS S DES SSS
Sbjct: 69 IG--ETNVERKAKKKRSKSVTSSSSSSSDSSASDSSSESEETSTSSSSEDSDTDESSSSS 126
Query: 492 SSSSSSGHKRHKKHKRNRSESSRSSRRHSSRASSNQIDQNRK 533
SSS+SS + S SS SS + +S ++ + +K
Sbjct: 127 SSSASSTTSSSSSDSDSDSSSSSSSSTSTDSSSDDEPPKKKK 168
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 52.4 bits (124), Expect = 2e-06
Identities = 112/514 (21%), Positives = 196/514 (38%), Gaps = 72/514 (14%)
Query: 260 PGVVEFLLEKLGIDESN---PPSLMRGLQSKNFSEDDFASALRKKQSASWALK----CVK 312
P + +LE G ES PSL G QSK E A+A Q+ + A K
Sbjct: 464 PNIDGKVLETEGSQESTVIRAPSL--GAQSKKEEEVKTATATLMLQNRATATSPDSGAKK 521
Query: 313 IGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALY------------ATKGSLNKA 360
I V F + A + K + Q A+ LY ATK +N
Sbjct: 522 ISVKTFPSASNTQATPDLLKGQQELTQQTNEETAKQILYNYLKEGSTDNDDATKRKVNLV 581
Query: 361 IEDFELALENCPTHRNARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALDETFKDAED 420
E + C + E LE++ K + ++ L L+ K+ ++
Sbjct: 582 FEKIQTLKSRAAGSAQGNNQACNSTSEVKDLLEQKSKLTIEVAELQRQLQLE--VKNQQN 639
Query: 421 ALQKLHKYMQKSLELREKQAEKEEKQKT--KKIETSAEKLRKLLKEEKRLKKKRRKSTSS 478
++ + ELR + EK E+ T +++E S +LRK L+E ++K +R +
Sbjct: 640 IKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQH--Q 697
Query: 479 SSVSSADESVSSSSSSSSSGHKRHKKHKRNRSESSRSSRRHSSRASSNQIDQNRKDECYP 538
+ + + +S + +S++ S A ++ Q ++D
Sbjct: 698 TEIRDLQDQLSEM---------------HDELDSAKRSEDREKGALIEELLQAKQD---- 738
Query: 539 VPANTSASFLNHKQEVEKLLGKQDRLQYEKTQIKEKDRCPLSSSSLEIPDDFGGRSEDPR 598
L K+E E LL K++R E T +K + +SS E+ + +
Sbjct: 739 -----LQDLLIAKEEQEDLLRKRER---ELTALKGALKEEVSSHDQEM--------DKLK 782
Query: 599 DFYNSYKTQAGSSKTEKPYKSERHFSSRRNSSDSFCRNSEDKIYGYRRFEKDIEGRKEHY 658
+ Y++ + QA E+ K+ +SR N+S+ +E ++ + + ++GR E
Sbjct: 783 EQYDA-ELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEEL 841
Query: 659 RRWEPGSVRHSTSPASSEYSWKSVEKYKKYAH-----SGSRDFSRHEQRYRLNTNQG-EY 712
R R E K+ E KKY + +R E++ ++ + E
Sbjct: 842 ERRVAQLQRQIEDLKGDEA--KAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALEN 899
Query: 713 EREDNYGEDIKTEVPEEDALSSKEHSESSVKKNL 746
E E G ++ E+ LS K ES K+ L
Sbjct: 900 ELEAAQG-NLSQTTQEQKQLSEKLKEESEQKEQL 932
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 52.0 bits (123), Expect = 2e-06
Identities = 62/273 (22%), Positives = 118/273 (43%), Gaps = 33/273 (12%)
Query: 325 DAMNEYNKALEIDKQNVEALVARGALYATKG---------SLNKAIEDFELALENCPTHR 375
+ + ++ LE+ ++ + L +R T+G S A E+ E AL
Sbjct: 368 ETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTE 427
Query: 376 NARKYLCQTLVERGGQLE---EEEKF-LNAESYYKKALALDETFKDAEDALQKLHKYMQK 431
AR+ L + E+ +E EEE+ L E K +D K +E+ + KL K
Sbjct: 428 EARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQK---- 483
Query: 432 SLELREKQAEKEEKQKTKKIETSAEKLRKLLK------EEKRLK----KKRRKSTSSSSV 481
L EK+ ++E++ TKK++T + ++ +K + + LK K++++S + +
Sbjct: 484 ---LHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEEL 540
Query: 482 SSADESVSSSSSSSSSGHKRHKKHKRNRSESSRSSRRHSSRASSNQ---IDQNRKDECYP 538
+++ + S + ++ + R R SS S + + NQ + + + E
Sbjct: 541 ELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNK 600
Query: 539 VPANTSASFLNHKQEVEKLLGKQDRLQYEKTQI 571
+ HK E+E L +QD L EK Q+
Sbjct: 601 HNKEITVMVEKHKTELESLKHQQDALWTEKLQV 633
Score = 36.6 bits (83), Expect = 0.090
Identities = 32/128 (25%), Positives = 61/128 (47%), Gaps = 10/128 (7%)
Query: 392 LEEEEKFLNAESYYKKALA-LDETFKDAEDALQKLHKYMQKSLELREKQAEKEEKQKTKK 450
+E+E L KK + L + ED++ L++ + + +EK+ EK KQK K+
Sbjct: 907 VEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKV-KQKAKE 965
Query: 451 IETSAEKLRKLLKEEKRLKKKRRKSTSSSSVSSAD------ESVSSSSSSSSSGHKRHKK 504
++ + +K KLL +E +LKK+ + S E ++S+ S R +
Sbjct: 966 MQETLKK--KLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLET 1023
Query: 505 HKRNRSES 512
+++ + ES
Sbjct: 1024 NQKEQIES 1031
Score = 35.0 bits (79), Expect = 0.26
Identities = 48/188 (25%), Positives = 79/188 (42%), Gaps = 27/188 (14%)
Query: 386 VERGGQLEEEEKFLNAESYYKKALALDETFKDAEDALQKLHKYMQKSLELREKQAEKEEK 445
V++ L E ++ L +S + +LA DET A L+KL + KSL K
Sbjct: 1102 VKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAH--LEKLEVDLNKSL-----------K 1148
Query: 446 QKTKKIETSAEKLRKLLKEEKRLKKKRRKSTSSSSVSSADESVSSSSSSSSSGHKRHKKH 505
+ T E E K+L EE KR+ S +S + + DE S SS H+K
Sbjct: 1149 ENTFLQEQLVEL--KMLAEED----KRKVSELTSKLKTTDEEFQSLKSS-------HEKS 1195
Query: 506 KRNRSESSRSSRRHSSRASSNQIDQNRKDECYPVPANTSASFLNHKQEVEKLLGKQDRLQ 565
++ + S ++ S + Q+D K + A T+ + +L + Q
Sbjct: 1196 NKSLEDKSLEFKKLSEELAI-QLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQ 1254
Query: 566 YEKTQIKE 573
+ T++KE
Sbjct: 1255 HRTTKVKE 1262
Score = 33.1 bits (74), Expect = 1.0
Identities = 79/430 (18%), Positives = 156/430 (36%), Gaps = 63/430 (14%)
Query: 387 ERGGQLEEEEKFLNAESYYKKALALDETFKDAEDALQKLHKYMQKSLELREKQA-EKEEK 445
E+ LE+ + + N S +KK F ++ +++L Q LEL+ K+A EK+E+
Sbjct: 1427 EKISALEQVDDWSNKFSEWKKKA--QSRFTQHQNTVKEL----QIQLELKSKEAYEKDEQ 1480
Query: 446 QKTKKIETSAEKLR-------------KLLKEEKRLKKKRRKSTS------------SSS 480
K E + R K+ K+E L+ + + T+ +
Sbjct: 1481 INLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIE 1540
Query: 481 VSSADESVSSSSSSSSSGHKRHKKHKRNRSESSRSSRRHSSRASSNQIDQNRKDECYPVP 540
+ S +E + + + HK + ++ E A + +
Sbjct: 1541 IESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAE 1600
Query: 541 ANTSASFLNH-----KQEVEKLLGKQDRLQYEK----TQIKEKDRCPLSSSSLEIPDDFG 591
T L H K + E+L +DRL+ E ++K K +++ ++
Sbjct: 1601 LETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQME 1660
Query: 592 GRSEDPRDFYNSYKTQAGSSKTEKPYKSERHFSSRRNSSDSFCRNSEDKIYGYRRFEKDI 651
+ E + S+ ++ + E+ + E H + S +S+ + R K++
Sbjct: 1661 EKEEQYKKGTESHLSELNTKLQER--EREVHILEEKLKS---VESSQSETLIVPRSAKNV 1715
Query: 652 EGRKEHYRRWEPGSVRHSTSPASSEYSWKSVEKYKKYAHSG---SRDFSRH--------E 700
E G V+ + S EK K G S H E
Sbjct: 1716 AAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQE 1775
Query: 701 QRYRLNTNQGEYEREDNYGEDIKTEVPEED---ALSSKEHSESSVKKN---LPQNLLNIF 754
+ +L + + + + ++ E+ E++ +L +H E KN QNL N+F
Sbjct: 1776 RLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVF 1835
Query: 755 NQIAEFEKEK 764
+ + + +EK
Sbjct: 1836 DDVQKTLQEK 1845
Score = 30.0 bits (66), Expect = 8.5
Identities = 46/241 (19%), Positives = 106/241 (43%), Gaps = 37/241 (15%)
Query: 278 PSLMRGLQSK-NFSEDDFASALRKKQSASWALKCVKIGVDYFKVGRHVDAMN-EYNKALE 335
P L+ ++++ N E A A R+KQ K+G + ++ + + + E+ + LE
Sbjct: 1915 PKLLSNMEAQHNDLEFKLAGAEREKQ---------KLGKEIVRLQKDLRMLRKEHQQELE 1965
Query: 336 IDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTHRNARKYLCQ----------TL 385
I K+ + + + + ED EL N + R++ Q T+
Sbjct: 1966 ILKKEYDQ--------EREEKIKQEQEDLELK-HNSTLKQLMREFNTQLAQKEQELEMTI 2016
Query: 386 VERGGQLEEEEKFLNAESYYKKALALDETFKDAEDALQKLHKYMQKSLELREKQAEKEEK 445
E + +E E L ES+ ++ L + + +D L++ K ++ L+ R E+E
Sbjct: 2017 KETINKAQEVEAEL-LESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAR----EEEMT 2071
Query: 446 QKTKKIETSAEKLRKLLKEEKRLKKKRRKSTSSSSVSSADESVSSSSSSSSSGHKRHKKH 505
K + ++T E+L+K K +++L+++ + ++ ++ ++ S + ++
Sbjct: 2072 AKVRDLQTQLEELQK--KYQQKLEQEENPGNDNVTIMELQTQLAQKTTLISDSKLKEQEF 2129
Query: 506 K 506
+
Sbjct: 2130 R 2130
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 52.0 bits (123), Expect = 2e-06
Identities = 82/355 (23%), Positives = 140/355 (39%), Gaps = 56/355 (15%)
Query: 394 EEEKFLNAESYYKKALALDETFKDAEDALQKLHKYMQK------SLELREKQAEKEEKQ- 446
++E+ E + ++ DE + D ++ + +K S + +QAE +K+
Sbjct: 443 DKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEA 502
Query: 447 -----KTKKIETSAEKLRKLLKEEKRL-------KKKRRKSTSSSSVSSADESVSSSSSS 494
+ K+ + + R+ +K+L + +RR+ TS+SS S+++ S SSS SS
Sbjct: 503 ATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSS 562
Query: 495 SSSGHKRHKKHKRNRSESSRSSR--RHSSRASSNQIDQNRKDECYPVPANTSASF---LN 549
S SG + R+ S SS SSR RHSS + S ++R P P+ T + +
Sbjct: 563 SYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSR--SRSRSFSSSPSPSPTPSPHRPSIR 620
Query: 550 HKQEVEKLLGKQDRLQYEKTQIKEKDRCPLSSSSLEIPDDFGGRSEDPRDFYNSYKTQAG 609
K E GK +K P ++ P + DPR+
Sbjct: 621 TKGEPAPPPGKAGEKSVKK---PAPPPAPPQATKTTAPVPEPTKPGDPRE---------- 667
Query: 610 SSKTEKPYKS---ERHFSSRRNSSDSFCRNSEDKIYGYRRFEKDIEGRKEHYRRWEPGSV 666
+ + E+P ++ R S + S S S R SV
Sbjct: 668 ARRKERPARTPPRRRTLSGSGSGSGSSYSGS--------------SSRSRSLSVSSVSSV 713
Query: 667 RHSTSPASSEYSWKSVEKYKKYAHSGSRDFSRHEQRYRLNTNQGEYEREDNYGED 721
+TS +SS +S S + Y A S SR + +G+ ++ED E+
Sbjct: 714 SSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEE 768
Score = 40.8 bits (94), Expect = 0.005
Identities = 42/223 (18%), Positives = 81/223 (36%), Gaps = 8/223 (3%)
Query: 413 ETFKDAEDALQKLHKYMQKSLELREKQAEKEEKQKTKKIETSAEKLRKLLKEEKRLKKKR 472
E F+ + H Y + RE++ E+E +Q+ ++ E ++ R+ + E+ +++
Sbjct: 386 ENFRVQYTETEPYHNYRE-----RERERERENRQRERERERERDRERERRQREREREREH 440
Query: 473 RKSTSSSSVSSADESVSSSSSSSSSGHKRHKKHKRNRSESSRSSRRHSSRASSNQIDQNR 532
+ E + H+ + K E + R S + S Q + +
Sbjct: 441 ERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPR-SPQPPSRQAEPPK 499
Query: 533 KDECYPVPANTSASFLNHKQEVEKLLGKQDRLQYEKTQIKEKDRCPLSSSSLEIPDDFGG 592
K+ P A K K+ + ++ + + + SS+S
Sbjct: 500 KEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSS 559
Query: 593 RSEDPRDFYNSYKTQAGSSKTEKPYKSERH--FSSRRNSSDSF 633
RS +S SS + +S RH FS R+ S SF
Sbjct: 560 RSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSF 602
>gi|118766347 zinc finger CCCH-type domain containing 6 [Homo
sapiens]
Length = 1189
Score = 51.6 bits (122), Expect = 3e-06
Identities = 45/164 (27%), Positives = 75/164 (45%), Gaps = 18/164 (10%)
Query: 434 ELREKQAEKEEKQKTKKIETSAEKLRKLLKEEKRLKKKRR---KSTSSSSVSSADESVSS 490
E++EK+A++ EKQK++K + K K +E+K+ K+++R K S SS S+D S+ S
Sbjct: 28 EIQEKEAKENEKQKSEKAYRKSRKKHKKEREKKKSKRRKREKHKHNSPSSDDSSDYSLDS 87
Query: 491 SSSSSSSGHKRHKKHKR------------NRSESSRSSRRHSSRASSNQIDQNRKDECYP 538
+ S HK+ R + S + +H+ + S + D+
Sbjct: 88 DVEHTESSHKKRTGFYRDYDIPFTQRGHISGSYITSKKGQHNKKFKSKEYDEYSTYSDDN 147
Query: 539 VPANTSASFLNHKQEVEKLLGKQDRLQYEKTQIKEKDRCPLSSS 582
+ +F N+ QE E+ Q + QY Q KE L SS
Sbjct: 148 FGNYSDDNFGNYGQETEEDFANQLK-QYR--QAKETSNIALGSS 188
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 51.2 bits (121), Expect = 4e-06
Identities = 34/155 (21%), Positives = 69/155 (44%), Gaps = 8/155 (5%)
Query: 424 KLHKYMQKSLELREKQAEKEEKQKTKKIETSAEKLRKLLKEEKRLKKKRRKSTSSSSVSS 483
K + ++ E RE++ K E++K +K E ++ + K+E+R +KKRR+ +
Sbjct: 52 KKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEE 111
Query: 484 ADESVSSSSS----SSSSGHKRHKKHKRNRSESSRSSRRHSSRASSNQIDQNRKDECYPV 539
++ +S G +R +K +R R E R+ R + + +K E V
Sbjct: 112 KEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQV 171
Query: 540 PANTSASFLNHKQEVEKLLGKQDRLQYEKTQIKEK 574
K++ K K++R + E+ + +E+
Sbjct: 172 GEKEE----ERKEKERKERKKRERNRKERKKERER 202
Score = 47.0 bits (110), Expect = 7e-05
Identities = 34/170 (20%), Positives = 69/170 (40%), Gaps = 9/170 (5%)
Query: 416 KDAEDALQKLHKYMQKSLELREKQAEKEEKQKTKKIETSAEKLRKLLK---------EEK 466
K+ E +K + +K REK+ ++E +K KK E E+ + + EEK
Sbjct: 53 KERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEK 112
Query: 467 RLKKKRRKSTSSSSVSSADESVSSSSSSSSSGHKRHKKHKRNRSESSRSSRRHSSRASSN 526
+KK+ K + E +R +K + E R R+ R
Sbjct: 113 EKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVG 172
Query: 527 QIDQNRKDECYPVPANTSASFLNHKQEVEKLLGKQDRLQYEKTQIKEKDR 576
+ ++ RK++ + K+E E+ ++ + + +K + ++K+R
Sbjct: 173 EKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKER 222
Score = 44.7 bits (104), Expect = 3e-04
Identities = 39/190 (20%), Positives = 76/190 (40%), Gaps = 19/190 (10%)
Query: 387 ERGGQLEEEEKFLNAESYYKKALALDETFKDAEDALQKLHKYMQKSLELREKQAEKEEKQ 446
ER + E EK E K+ E K+ + ++ + K E +EK+ +KE+K+
Sbjct: 65 EREKRKREREKERKRERGKKEKKG--ERKKEERERKKRRREKENKEGEEKEKRKKKEKKE 122
Query: 447 KTKKIETSAEKLRKLLKEEKRLKKKRRKSTSSSSVSSADESVSSSSSSSSSGHKRHKKHK 506
+ + + E+ RK +E KR ++K R+ + G K ++ +
Sbjct: 123 RGRTSKEGKERERK--EERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKE 180
Query: 507 RNRSESSRSSRRHSSRASSNQIDQNRKDECYPVPANTSASFLNHKQEVEKLLGKQDRLQY 566
+ R E + R R + + R+ K+ +K K++R +
Sbjct: 181 KERKERKKRERNRKERKKERERKERRE---------------RKKERKKKEERKKERQKD 225
Query: 567 EKTQIKEKDR 576
+T +EK+R
Sbjct: 226 RQTNWREKER 235
Score = 40.0 bits (92), Expect = 0.008
Identities = 45/233 (19%), Positives = 88/233 (37%), Gaps = 37/233 (15%)
Query: 434 ELREKQAEKEEKQKTKKIETSAEKLRKLLKEEKRL---KKKRRKSTSSS------SVSSA 484
E+RE++ E E +++ KK E +E+ ++ + EKR +K+R++
Sbjct: 37 EIREREREIETRKEGKK-ERESERKKERREREKRKREREKERKRERGKKEKKGERKKEER 95
Query: 485 DESVSSSSSSSSSGHKRHKKHKRNRSESSRSSRRHSSRASSNQIDQNRKDECYPVPANTS 544
+ + G ++ K+ K+ + E R+S+ R + + + E
Sbjct: 96 ERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERE------- 148
Query: 545 ASFLNHKQEVEKLLGKQDRLQYEKTQIKEKDRCPLSSSSLEIPDDFGGRSEDPRDFYNSY 604
K+E EK +++R + E+ Q+ EK+ R E R
Sbjct: 149 ----RKKEEREKERERKERKKRERKQVGEKEE---------------ERKEKERKERKKR 189
Query: 605 KTQAGSSKTEKPYKSERHFSSRRNSSDSFCR-NSEDKIYGYRRFEKDIEGRKE 656
+ K E+ K R R + + +D+ +R E+ RKE
Sbjct: 190 ERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKE 242
Score = 39.7 bits (91), Expect = 0.011
Identities = 29/150 (19%), Positives = 68/150 (45%), Gaps = 4/150 (2%)
Query: 387 ERGGQLEEEEKFLNAESYYKKALALDETFKDAEDALQKLHKYMQKSLELREKQAEKEEKQ 446
ER + E+E E +K E + +++ ++ K +K E +E++ +KEE++
Sbjct: 96 ERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEERE 155
Query: 447 KTKKIETSAEKLRKLL---KEEKRLK-KKRRKSTSSSSVSSADESVSSSSSSSSSGHKRH 502
K ++ + ++ RK + +EE++ K +K RK + E K+
Sbjct: 156 KERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKK 215
Query: 503 KKHKRNRSESSRSSRRHSSRASSNQIDQNR 532
++ K+ R + +++ R R + ++ +
Sbjct: 216 EERKKERQKDRQTNWREKERGKRERKERKK 245
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.357
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,429,003
Number of Sequences: 37866
Number of extensions: 1359295
Number of successful extensions: 17615
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 434
Number of HSP's successfully gapped in prelim test: 872
Number of HSP's that attempted gapping in prelim test: 8666
Number of HSP's gapped (non-prelim): 5354
length of query: 770
length of database: 18,247,518
effective HSP length: 110
effective length of query: 660
effective length of database: 14,082,258
effective search space: 9294290280
effective search space used: 9294290280
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.