Guide to the Human Genome
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Search of human proteins with 33239445

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|33239445 eukaryotic translation initiation factor 3, subunit
9 eta, 116kDa [Homo sapiens]
         (814 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|33239445 eukaryotic translation initiation factor 3, subunit ...  1671   0.0  
gi|83367072 eukaryotic translation initiation factor 3, subunit ...  1671   0.0  
gi|54873624 eukaryotic translation initiation factor 2A [Homo sa...    89   2e-17
gi|27894378 chloride intracellular channel 6 [Homo sapiens]            59   2e-08
gi|30795231 brain abundant, membrane attached signal protein 1 [...    56   1e-07
gi|33286446 opioid growth factor receptor [Homo sapiens]               53   1e-06
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              53   1e-06
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    52   2e-06
gi|23503317 coiled-coil domain containing 96 [Homo sapiens]            50   6e-06
gi|193083172 nuclear assembly factor 1 homolog isoform b [Homo s...    50   8e-06
gi|193083157 nuclear assembly factor 1 homolog isoform a [Homo s...    50   8e-06
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]          49   1e-05
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]       48   3e-05
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]       48   3e-05
gi|117938759 GNAS complex locus XLas [Homo sapiens]                    48   4e-05
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]       48   4e-05
gi|153070260 myristoylated alanine-rich protein kinase C substra...    47   5e-05
gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Hom...    47   9e-05
gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Hom...    47   9e-05
gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo ...    47   9e-05
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ...    47   9e-05
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ...    47   9e-05
gi|117938310 sine oculis binding protein homolog [Homo sapiens]        47   9e-05
gi|140972063 protein phosphatase 1, regulatory subunit 9B [Homo ...    46   1e-04
gi|163965366 nascent polypeptide-associated complex alpha subuni...    46   1e-04
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    46   2e-04
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    46   2e-04
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     46   2e-04
gi|118601081 heterogeneous nuclear ribonucleoprotein U-like 2 [H...    46   2e-04
gi|226053185 paternally expressed 3 isoform 3 [Homo sapiens]           45   2e-04

>gi|33239445 eukaryotic translation initiation factor 3, subunit 9
           eta, 116kDa [Homo sapiens]
          Length = 814

 Score = 1671 bits (4327), Expect = 0.0
 Identities = 814/814 (100%), Positives = 814/814 (100%)

Query: 1   MQDAENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEA 60
           MQDAENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEA
Sbjct: 1   MQDAENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEA 60

Query: 61  GPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSR 120
           GPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSR
Sbjct: 61  GPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSR 120

Query: 121 AQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEA 180
           AQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEA
Sbjct: 121 AQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEA 180

Query: 181 DGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKITNDFYPEEDGKTKGYIFLEYASP 240
           DGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKITNDFYPEEDGKTKGYIFLEYASP
Sbjct: 181 DGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKITNDFYPEEDGKTKGYIFLEYASP 240

Query: 241 AHAVDAVKNADGYKLDKQHTFRVNLFTDFDKYMTISDEWDIPEKQPFKDLGNLRYWLEEA 300
           AHAVDAVKNADGYKLDKQHTFRVNLFTDFDKYMTISDEWDIPEKQPFKDLGNLRYWLEEA
Sbjct: 241 AHAVDAVKNADGYKLDKQHTFRVNLFTDFDKYMTISDEWDIPEKQPFKDLGNLRYWLEEA 300

Query: 301 ECRDQYSVIFESGDRTSIFWNDVKDPVSIEERARWTETYVRWSPKGTYLATFHQRGIALW 360
           ECRDQYSVIFESGDRTSIFWNDVKDPVSIEERARWTETYVRWSPKGTYLATFHQRGIALW
Sbjct: 301 ECRDQYSVIFESGDRTSIFWNDVKDPVSIEERARWTETYVRWSPKGTYLATFHQRGIALW 360

Query: 361 GGEKFKQIQRFSHQGVQLIDFSPCERYLVTFSPLMDTQDDPQAIIIWDILTGHKKRGFHC 420
           GGEKFKQIQRFSHQGVQLIDFSPCERYLVTFSPLMDTQDDPQAIIIWDILTGHKKRGFHC
Sbjct: 361 GGEKFKQIQRFSHQGVQLIDFSPCERYLVTFSPLMDTQDDPQAIIIWDILTGHKKRGFHC 420

Query: 421 ESSAHWPIFKWSHDGKFFARMTLDTLSIYETPSMGLLDKKSLKISGIKDFSWSPGGNIIA 480
           ESSAHWPIFKWSHDGKFFARMTLDTLSIYETPSMGLLDKKSLKISGIKDFSWSPGGNIIA
Sbjct: 421 ESSAHWPIFKWSHDGKFFARMTLDTLSIYETPSMGLLDKKSLKISGIKDFSWSPGGNIIA 480

Query: 481 FWVPEDKDIPARVTLMQLPTRQEIRVRNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQGV 540
           FWVPEDKDIPARVTLMQLPTRQEIRVRNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQGV
Sbjct: 481 FWVPEDKDIPARVTLMQLPTRQEIRVRNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQGV 540

Query: 541 VTNFEIFRMREKQVPVDVVEMKETIIAFAWEPNGSKFAVLHGEAPRISVSFYHVKNNGKI 600
           VTNFEIFRMREKQVPVDVVEMKETIIAFAWEPNGSKFAVLHGEAPRISVSFYHVKNNGKI
Sbjct: 541 VTNFEIFRMREKQVPVDVVEMKETIIAFAWEPNGSKFAVLHGEAPRISVSFYHVKNNGKI 600

Query: 601 ELIKMFDKQQANTIFWSPQGQFVVLAGLRSMNGALAFVDTSDCTVMNIAEHYMASDVEWD 660
           ELIKMFDKQQANTIFWSPQGQFVVLAGLRSMNGALAFVDTSDCTVMNIAEHYMASDVEWD
Sbjct: 601 ELIKMFDKQQANTIFWSPQGQFVVLAGLRSMNGALAFVDTSDCTVMNIAEHYMASDVEWD 660

Query: 661 PTGRYVVTSVSWWSHKVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQEQIKQI 720
           PTGRYVVTSVSWWSHKVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQEQIKQI
Sbjct: 661 PTGRYVVTSVSWWSHKVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQEQIKQI 720

Query: 721 KKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRKYRKMAQELYMEQKNERLELRG 780
           KKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRKYRKMAQELYMEQKNERLELRG
Sbjct: 721 KKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRKYRKMAQELYMEQKNERLELRG 780

Query: 781 GVDTDELDSNVDDWEEETIEFFVTEEIIPLGNQE 814
           GVDTDELDSNVDDWEEETIEFFVTEEIIPLGNQE
Sbjct: 781 GVDTDELDSNVDDWEEETIEFFVTEEIIPLGNQE 814


>gi|83367072 eukaryotic translation initiation factor 3, subunit 9
           eta, 116kDa [Homo sapiens]
          Length = 814

 Score = 1671 bits (4327), Expect = 0.0
 Identities = 814/814 (100%), Positives = 814/814 (100%)

Query: 1   MQDAENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEA 60
           MQDAENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEA
Sbjct: 1   MQDAENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEA 60

Query: 61  GPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSR 120
           GPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSR
Sbjct: 61  GPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSR 120

Query: 121 AQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEA 180
           AQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEA
Sbjct: 121 AQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEA 180

Query: 181 DGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKITNDFYPEEDGKTKGYIFLEYASP 240
           DGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKITNDFYPEEDGKTKGYIFLEYASP
Sbjct: 181 DGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKITNDFYPEEDGKTKGYIFLEYASP 240

Query: 241 AHAVDAVKNADGYKLDKQHTFRVNLFTDFDKYMTISDEWDIPEKQPFKDLGNLRYWLEEA 300
           AHAVDAVKNADGYKLDKQHTFRVNLFTDFDKYMTISDEWDIPEKQPFKDLGNLRYWLEEA
Sbjct: 241 AHAVDAVKNADGYKLDKQHTFRVNLFTDFDKYMTISDEWDIPEKQPFKDLGNLRYWLEEA 300

Query: 301 ECRDQYSVIFESGDRTSIFWNDVKDPVSIEERARWTETYVRWSPKGTYLATFHQRGIALW 360
           ECRDQYSVIFESGDRTSIFWNDVKDPVSIEERARWTETYVRWSPKGTYLATFHQRGIALW
Sbjct: 301 ECRDQYSVIFESGDRTSIFWNDVKDPVSIEERARWTETYVRWSPKGTYLATFHQRGIALW 360

Query: 361 GGEKFKQIQRFSHQGVQLIDFSPCERYLVTFSPLMDTQDDPQAIIIWDILTGHKKRGFHC 420
           GGEKFKQIQRFSHQGVQLIDFSPCERYLVTFSPLMDTQDDPQAIIIWDILTGHKKRGFHC
Sbjct: 361 GGEKFKQIQRFSHQGVQLIDFSPCERYLVTFSPLMDTQDDPQAIIIWDILTGHKKRGFHC 420

Query: 421 ESSAHWPIFKWSHDGKFFARMTLDTLSIYETPSMGLLDKKSLKISGIKDFSWSPGGNIIA 480
           ESSAHWPIFKWSHDGKFFARMTLDTLSIYETPSMGLLDKKSLKISGIKDFSWSPGGNIIA
Sbjct: 421 ESSAHWPIFKWSHDGKFFARMTLDTLSIYETPSMGLLDKKSLKISGIKDFSWSPGGNIIA 480

Query: 481 FWVPEDKDIPARVTLMQLPTRQEIRVRNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQGV 540
           FWVPEDKDIPARVTLMQLPTRQEIRVRNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQGV
Sbjct: 481 FWVPEDKDIPARVTLMQLPTRQEIRVRNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQGV 540

Query: 541 VTNFEIFRMREKQVPVDVVEMKETIIAFAWEPNGSKFAVLHGEAPRISVSFYHVKNNGKI 600
           VTNFEIFRMREKQVPVDVVEMKETIIAFAWEPNGSKFAVLHGEAPRISVSFYHVKNNGKI
Sbjct: 541 VTNFEIFRMREKQVPVDVVEMKETIIAFAWEPNGSKFAVLHGEAPRISVSFYHVKNNGKI 600

Query: 601 ELIKMFDKQQANTIFWSPQGQFVVLAGLRSMNGALAFVDTSDCTVMNIAEHYMASDVEWD 660
           ELIKMFDKQQANTIFWSPQGQFVVLAGLRSMNGALAFVDTSDCTVMNIAEHYMASDVEWD
Sbjct: 601 ELIKMFDKQQANTIFWSPQGQFVVLAGLRSMNGALAFVDTSDCTVMNIAEHYMASDVEWD 660

Query: 661 PTGRYVVTSVSWWSHKVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQEQIKQI 720
           PTGRYVVTSVSWWSHKVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQEQIKQI
Sbjct: 661 PTGRYVVTSVSWWSHKVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQEQIKQI 720

Query: 721 KKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRKYRKMAQELYMEQKNERLELRG 780
           KKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRKYRKMAQELYMEQKNERLELRG
Sbjct: 721 KKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRKYRKMAQELYMEQKNERLELRG 780

Query: 781 GVDTDELDSNVDDWEEETIEFFVTEEIIPLGNQE 814
           GVDTDELDSNVDDWEEETIEFFVTEEIIPLGNQE
Sbjct: 781 GVDTDELDSNVDDWEEETIEFFVTEEIIPLGNQE 814


>gi|54873624 eukaryotic translation initiation factor 2A [Homo
           sapiens]
          Length = 585

 Score = 88.6 bits (218), Expect = 2e-17
 Identities = 91/396 (22%), Positives = 161/396 (40%), Gaps = 39/396 (9%)

Query: 339 YVRWSPKGTYLATFHQRG-IALWGGEKFKQIQRFSHQGVQ---------LIDFSPCERYL 388
           + R S K   +  F + G +  WG  +   I   +++G+           ++FSP    L
Sbjct: 31  FPRESGKNCKVCIFSKDGTLFAWGNGEKVNIISVTNKGLLHSFDLLKAVCLEFSPKNTVL 90

Query: 389 VTFSPLMDTQDDPQAII---IWDILTGHKKRGFHCESSAHWPIFKWSHDGKFFARMTLDT 445
            T+ P   ++D    I    ++D+ TG   + F  +   +W    WS D    AR   + 
Sbjct: 91  ATWQPYTTSKDGTAGIPNLQLYDVKTGTCLKSFIQKKMQNW-CPSWSEDETLCARNVNNE 149

Query: 446 LSIYETPSMGLLDKKSLKISGIKDFSWSPGGNI--IAFWVPEDKDIPARVTLMQLPT--- 500
           +  +E  +   +  K L +  I DF  SPG     +A +VP  K  P+ V L Q P    
Sbjct: 150 VHFFENNNFNTIANK-LHLQKINDFVLSPGPQPYKVAVYVPGSKGAPSFVRLYQYPNFAG 208

Query: 501 -RQEIRVRNLFNVVDCKLHWQKNGDYLCV----KVDRTPKGTQGVVTNFEIFRMREKQVP 555
               +  ++ F      + W K    + V     VD+T     G  T   I    E  V 
Sbjct: 209 PHAALANKSFFKADKVTMLWNKKATAVLVIASTDVDKTGASYYGEQTLHYIATNGESAV- 267

Query: 556 VDVVEMKET--IIAFAWEPNGSKFAVLHGEAPRISVSFYHVKNNGKIELIKMFDKQQANT 613
              V++ +   I    W  + ++F  ++G  P  +  F     N K + +  F     N 
Sbjct: 268 ---VQLPKNGPIYDVVWNSSSTEFCAVYGFMPAKATIF-----NLKCDPVFDFGTGPRNA 319

Query: 614 IFWSPQGQFVVLAGLRSMNGALAFVDTSDCTVMNIAEHYMASDVEWDPTGRYVVTSVSWW 673
            ++SP G  +VLAG  ++ G +   D  +  +++      ++   W P G +++T+    
Sbjct: 320 AYYSPHGHILVLAGFGNLRGQMEVWDVKNYKLISKPVASDSTYFAWCPDGEHILTATCAP 379

Query: 674 SHKVDNAYWLWTFQGRLLQK---NNKDRFCQLLWRP 706
             +V+N Y +W + G +L K    +     Q+ W+P
Sbjct: 380 RLRVNNGYKIWHYTGSILHKYDVPSNAELWQVSWQP 415


>gi|27894378 chloride intracellular channel 6 [Homo sapiens]
          Length = 686

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 71/223 (31%), Positives = 92/223 (41%), Gaps = 46/223 (20%)

Query: 11  EAAE-ERAEPGQQQPAAEPPP-AEGLLRPAGPGAP--EAAGTEAS--SEEV--------- 55
           EAAE E   PG Q P   P P AE   RP  PGA   EA G E S  +EE          
Sbjct: 3   EAAEPEGVAPGPQGPPEVPAPLAE---RPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKE 59

Query: 56  ---GIAEAGPESEVRTEPAA--EAEAASG-PSESPSPPAAEELPGSH----AEPPVPAQG 105
              G  + GPE+E R    A  E EA  G P  +  P   EE  G+     A P   AQG
Sbjct: 60  AGGGGPDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQG 119

Query: 106 EAPGEQARD----------ERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSD 155
           E  GE  R+          E ++ R +     A G  G + +AE    +N +A+ P+   
Sbjct: 120 EPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPA--- 176

Query: 156 PEDFVDDVSEEELLGDVLKDRPQEADGIDSV-IVVDNVPQVGP 197
                D V  E  +GD +       D +D+   + DN+   GP
Sbjct: 177 ----GDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGP 215



 Score = 39.3 bits (90), Expect = 0.015
 Identities = 53/199 (26%), Positives = 74/199 (37%), Gaps = 20/199 (10%)

Query: 5   ENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPES 64
           E   VP+  EE +   Q + A+    A+G  R      PE +             A PE 
Sbjct: 91  EGAEVPQGGEETSGAQQVEGASPGRGAQGEPRGEAQREPEDS-------------AAPER 137

Query: 65  EVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQA- 123
           +   E   E    S   E+     AE   G + E   PA      E    +  D+   A 
Sbjct: 138 QEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPAGDSVEAEGRVGDSVDAEGPAG 197

Query: 124 VSEDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFV----DDVSEEELLGDVLKDRPQE 179
            S DA G  G   +AE  A ++ DA E    D  D      D V  E  +GD ++     
Sbjct: 198 DSVDAEGPLGDNIQAEGPAGDSVDA-EGRVGDSVDAEGPAGDSVDAEGRVGDSVEAGDPA 256

Query: 180 ADGIDS-VIVVDNVPQVGP 197
            DG+++ V   D+V   GP
Sbjct: 257 GDGVEAGVPAGDSVEAEGP 275



 Score = 38.9 bits (89), Expect = 0.019
 Identities = 28/73 (38%), Positives = 33/73 (45%), Gaps = 5/73 (6%)

Query: 74  AEAASGPSESPSPPAAEELPGSHAE---PPVPAQGEAPGEQARD--ERSDSRAQAVSEDA 128
           AEAA     +P P    E+P   AE    P  A GEA G +  +  E +   A AV E  
Sbjct: 2   AEAAEPEGVAPGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAG 61

Query: 129 GGNEGRAAEAEPR 141
           GG   R  EAE R
Sbjct: 62  GGGPDRGPEAEAR 74



 Score = 37.4 bits (85), Expect = 0.056
 Identities = 43/149 (28%), Positives = 57/149 (38%), Gaps = 13/149 (8%)

Query: 4   AENVAVPEAAEERAEPGQQQ-PAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGP 62
           AE + V         PG+    AAE     G+ + +   AP  A  +A  + VG    GP
Sbjct: 308 AEAIEVAAGESAGRSPGELAWDAAEEAEVPGV-KGSEEAAPGDARADAGEDRVG---DGP 363

Query: 63  ESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQ 122
           + E   +      +  GP E  +    EE P S         GEA    A  E   S   
Sbjct: 364 QQEPGEDEERRERSPEGPREEEAAGGEEESPDS------SPHGEASRGAAEPEAQLSNHL 417

Query: 123 AVSEDAGGNEGRAAEAEPRALENGDADEP 151
           A    A G+ G AA    R  E+G+A EP
Sbjct: 418 AEEGPAEGS-GEAARVNGRR-EDGEASEP 444



 Score = 33.5 bits (75), Expect = 0.81
 Identities = 52/176 (29%), Positives = 68/176 (38%), Gaps = 31/176 (17%)

Query: 24  PAAEPPPAEGLLR-------PAGPGAPEAAGTEASSEEVGI-AEAGPESEVRTEPAAEAE 75
           PA +   AEG +        PAG    +A G    S E G  A  G E+ V    + EAE
Sbjct: 215 PAGDSVDAEGRVGDSVDAEGPAGDSV-DAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAE 273

Query: 76  AASGPSESPSPPA--AEELPGS-----------HAEPPVPAQGE----APGEQARDERSD 118
             +G S     PA  A  + G             AE    A GE    +PGE A D   +
Sbjct: 274 GPAGDSMDAEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPGELAWDAAEE 333

Query: 119 SRAQAV--SEDAGGNEGRAAEAEPRALENGDADEPSFSDP--EDFVDDVSEEELLG 170
           +    V  SE+A   + RA   E R + +G   EP   +   E   +   EEE  G
Sbjct: 334 AEVPGVKGSEEAAPGDARADAGEDR-VGDGPQQEPGEDEERRERSPEGPREEEAAG 388


>gi|30795231 brain abundant, membrane attached signal protein 1
           [Homo sapiens]
          Length = 227

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 51/189 (26%), Positives = 80/189 (42%), Gaps = 23/189 (12%)

Query: 2   QDAENVAVPEAAEERAEPGQQQPAAEPPPAE---GLLRPAGPGAPEAAGTEASSEEVGIA 58
           ++ +  A   A EE   P + +P A   PAE   G  +P      +A   E   +     
Sbjct: 20  KEKDKKAEGAATEEEGTPKESEPQAAAEPAEAKEGKEKPDQDAEGKAEEKEGEKDAAAAK 79

Query: 59  EAGPESEV-RTEPAAEA-----------EAASGPSESPSPPAAEELPGSHAEPPVPAQGE 106
           E  P++E  +TE AAEA           +AA GP+     P A E   + AE   PA GE
Sbjct: 80  EEAPKAEPEKTEGAAEAKAEPPKAPEQEQAAPGPAAGGEAPKAAEAAAAPAESAAPAAGE 139

Query: 107 APG-EQARDERSDSRAQAVSED-------AGGNEGRAAEAEPRALENGDADEPSFSDPED 158
            P  E+   +++++ A   +++       A  ++  ++EA P + E   A E   S P+ 
Sbjct: 140 EPSKEEGEPKKTEAPAAPAAQETKSDGAPASDSKPGSSEAAPSSKETPAATEAPSSTPKA 199

Query: 159 FVDDVSEEE 167
                S EE
Sbjct: 200 QGPAASAEE 208



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 38/107 (35%), Positives = 49/107 (45%), Gaps = 19/107 (17%)

Query: 10  PEAAEERAEPGQQQ-PAA--EPPPAEGLLR----PAGPGAPEAA--GTEASSEEVGIAEA 60
           P+AAE  A P +   PAA  EP   EG  +    PA P A E    G  AS  + G +EA
Sbjct: 120 PKAAEAAAAPAESAAPAAGEEPSKEEGEPKKTEAPAAPAAQETKSDGAPASDSKPGSSEA 179

Query: 61  GPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEA 107
            P S  +  PAA        +E+PS     + P + AE P P +  A
Sbjct: 180 APSS--KETPAA--------TEAPSSTPKAQGPAASAEEPKPVEAPA 216



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 32/99 (32%), Positives = 45/99 (45%), Gaps = 13/99 (13%)

Query: 8   AVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPE--AAGTEASSEEVGIAEAGP--- 62
           A P A E   EP +++   EP   E    PA P A E  + G  AS  + G +EA P   
Sbjct: 133 AAPAAGE---EPSKEE--GEPKKTEA---PAAPAAQETKSDGAPASDSKPGSSEAAPSSK 184

Query: 63  ESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPV 101
           E+   TE  +    A GP+ S   P   E P ++++  V
Sbjct: 185 ETPAATEAPSSTPKAQGPAASAEEPKPVEAPAANSDQTV 223



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 37/134 (27%), Positives = 53/134 (39%), Gaps = 24/134 (17%)

Query: 44  EAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASGPSESPSPPA---AEELPGSHAEPP 100
           +A   +  +E     E G   E   + AAE   A    E P   A   AEE  G   +  
Sbjct: 18  KAKEKDKKAEGAATEEEGTPKESEPQAAAEPAEAKEGKEKPDQDAEGKAEEKEGE--KDA 75

Query: 101 VPAQGEAPGEQARDERSDSRAQAVSED--------------AGGNEGRAAEAEPRALEN- 145
             A+ EAP  +A  E+++  A+A +E               AGG   +AAEA     E+ 
Sbjct: 76  AAAKEEAP--KAEPEKTEGAAEAKAEPPKAPEQEQAAPGPAAGGEAPKAAEAAAAPAESA 133

Query: 146 --GDADEPSFSDPE 157
                +EPS  + E
Sbjct: 134 APAAGEEPSKEEGE 147


>gi|33286446 opioid growth factor receptor [Homo sapiens]
          Length = 677

 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 45/147 (30%), Positives = 58/147 (39%), Gaps = 21/147 (14%)

Query: 17  AEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEA-- 74
           A P   +PA  P    G  RPAGP   E A  E+ SE  G   AGP  +   E  +E   
Sbjct: 527 AGPAGDEPAESPSETPGP-RPAGPAGDEPA--ESPSETPGPRPAGPAGDEPAESPSETPG 583

Query: 75  ---------EAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQ--- 122
                    E A  PSE+P P  A       AE P    G  P   A DE ++S ++   
Sbjct: 584 PSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG 643

Query: 123 ----AVSEDAGGNEGRAAEAEPRALEN 145
                 + D     G AAE +   +E+
Sbjct: 644 PSPAGPTRDEPAKAGEAAELQDAEVES 670



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 47/175 (26%), Positives = 64/175 (36%), Gaps = 20/175 (11%)

Query: 9   VPEAAEERAEPGQQQPAAE---PPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESE 65
           V E  E R  P +  P +    P P+     PAGP   E A  E+ SE  G   AGP  +
Sbjct: 500 VEEDTEGRTGPKEGTPGSPSETPGPS-----PAGPAGDEPA--ESPSETPGPRPAGPAGD 552

Query: 66  VRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVS 125
                    E A  PSE+P P  A       AE P    G +P    RDE ++S ++   
Sbjct: 553 ---------EPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPG 603

Query: 126 EDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEA 180
               G  G      P          P+  +P +   +       G   +D P +A
Sbjct: 604 PRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPT-RDEPAKA 657



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 36/105 (34%), Positives = 46/105 (43%), Gaps = 17/105 (16%)

Query: 17  AEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEA 76
           A P + +PA  P    G  RPAGP   E A  E+ SE  G   AGP  +         E 
Sbjct: 587 AGPTRDEPAESPSETPGP-RPAGPAGDEPA--ESPSETPGPRPAGPAGD---------EP 634

Query: 77  ASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRA 121
           A  PSE+P P  A    G   + P  A GEA   Q  +  S +++
Sbjct: 635 AESPSETPGPSPA----GPTRDEPAKA-GEAAELQDAEVESSAKS 674



 Score = 39.7 bits (91), Expect = 0.011
 Identities = 32/122 (26%), Positives = 47/122 (38%), Gaps = 7/122 (5%)

Query: 37  PAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSH 96
           PA  G P+A  +E   EE      GP+      P+        P  SP+ PA +E   S 
Sbjct: 485 PAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSET------PGPSPAGPAGDEPAESP 538

Query: 97  AEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDA-DEPSFSD 155
           +E P P      G++  +  S++     +  AG     +    P     G   DEP+ S 
Sbjct: 539 SETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESP 598

Query: 156 PE 157
            E
Sbjct: 599 SE 600


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 64/219 (29%), Positives = 91/219 (41%), Gaps = 44/219 (20%)

Query: 3    DAENVAVPEAAEERAEP-GQQQPAAEP---PPAEGLLRPAGPGA----------PEAAGT 48
            ++E V  PEA  +  E  G+ QP +E    P AEG  +P               PE+ G 
Sbjct: 1847 ESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGA 1906

Query: 49   EASSEEVGIAEAGPESE----VRTE----------PAAEAEAASGPSESPSPPAAEELPG 94
            EA   E    EA PE+E    + TE           A EAE A+  +E  + P +E +  
Sbjct: 1907 EAPEAE---KEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIES 1963

Query: 95   SHAE---PPVPAQGEAPGEQARDERSDSRAQAVSED--AGGNEGRAAEAEPRALENGDAD 149
              AE    P     EA   +   + ++  AQ  SED  A   EG   EAE  A    D  
Sbjct: 1964 QEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGV 2023

Query: 150  EPSFSDPEDFVDDVSEEELLGDVLK---DRPQEADGIDS 185
            E   + P+   ++  E E  G+  K   D   E+DG+++
Sbjct: 2024 E---AQPKSEGEEAQEVE--GETQKTEGDAQPESDGVEA 2057



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 54/189 (28%), Positives = 82/189 (43%), Gaps = 27/189 (14%)

Query: 3    DAENVAVPEAAEERAEP--------GQQQPAAEP---PPAEGLLRPAGPG--APEAAGTE 49
            +++ V  PEA EE  E         G+  P +E      AEG  +P   G  APEA G  
Sbjct: 2051 ESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEA 2110

Query: 50   ASSEEVGI----AEAGPESEVRTEPAAEAEA-------ASGPSESPSPPAAEELPGSHAE 98
              +E +       EA PESE    P AE EA        +  +E  + P +E +    AE
Sbjct: 2111 QKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAE 2170

Query: 99   PPVPAQGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPED 158
                AQ E  G +A +   +++ ++   +A   EG  A+ E   +E  +A+E +  +PE 
Sbjct: 2171 E--EAQPELEGVEAPEAEGEAQPESEGIEAPEAEGE-AQPELEGVEAPEAEEEAQPEPEG 2227

Query: 159  FVDDVSEEE 167
                 +E E
Sbjct: 2228 VETPEAEGE 2236



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 51/159 (32%), Positives = 63/159 (39%), Gaps = 30/159 (18%)

Query: 2    QDAENVAVPEA-------AEERAEPGQQQPAAEPPPAEGLLRPAGPG--APEAAGTEASS 52
            QDAE  A PE+       AEE A+P  +    E P AEG  +P   G  APEA G     
Sbjct: 2151 QDAEGEAQPESEGIEAQEAEEEAQP--ELEGVEAPEAEGEAQPESEGIEAPEAEG----- 2203

Query: 53   EEVGIAEAGPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQA 112
                  EA PE E    P AE EA       P P    E P +  E    ++GE  GE+ 
Sbjct: 2204 ------EAQPELEGVEAPEAEEEA------QPEPEGV-ETPEAEGEAQPESEGETQGEK- 2249

Query: 113  RDERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDADEP 151
            +     S     SE+A  +     E  P    +   D P
Sbjct: 2250 KGSPQVSLGDGQSEEASESSSPVPEDRPTPPPSPGGDTP 2288



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 52/179 (29%), Positives = 64/179 (35%), Gaps = 32/179 (17%)

Query: 1    MQDAENVAVPEAAEERAEP------------------GQQQPAA----------EPPPAE 32
            MQ+AE  A PE+    A+P                  G  QP +          E   AE
Sbjct: 2009 MQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAE 2068

Query: 33   GLLRPA-GPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASGPSESPSPPAAEE 91
            G ++ A G   PE+   +A   E    EA PESE    P AE EA             E 
Sbjct: 2069 GEVQEAEGEAHPESEDVDAQEAE---GEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEA 2125

Query: 92   LPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDADE 150
             P S       A+GEA  E    E  D+  +A  E  G     A E     LE  +A E
Sbjct: 2126 QPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPE 2184



 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 52/202 (25%), Positives = 86/202 (42%), Gaps = 27/202 (13%)

Query: 3    DAENVAVPE--AAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAG-TEASSEEVGIAE 59
            +AE  A PE  + E     G+ +P +E   A+     A   A EA G T+  SE +   E
Sbjct: 1910 EAEKEAQPETESVEALETEGEDEPESEGAEAQ----EAEEAAQEAEGQTQPESEVIESQE 1965

Query: 60   AGPESEVRTE--PAAEAEAASGPSESPSPPAAEELPGSHAEPPV-----PAQGEAPGEQA 112
            A  E++  +E   A E E  +  +E  + P +E++    AE  +      AQ E+ G +A
Sbjct: 1966 AEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEA 2025

Query: 113  RDERSDSRAQAVSEDAGGNEG---------RAAEAEPRALENGDADEPSFSDPEDFVDDV 163
            + +     AQ V  +    EG          A EAE  A E     + +  +     +DV
Sbjct: 2026 QPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDV 2085

Query: 164  SEEELLGDVLKDRPQEADGIDS 185
              +E  G+       E++G+++
Sbjct: 2086 DAQEAEGEA----QPESEGVEA 2103



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 59/224 (26%), Positives = 88/224 (39%), Gaps = 43/224 (19%)

Query: 2    QDAENVAVPEA---------AEERAEPGQQQPAAEP---PPAEGLLRPAGPGA-PEAAGT 48
            Q+AE  A PE+          E +   G+ QP +E    P AEG ++ A   A PE+ G 
Sbjct: 1964 QEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGV 2023

Query: 49   EASSEEVG-------------IAEAGPESEVRTEPAAEAEAASG-----PSESPSPPAAE 90
            EA  +  G               +A PES+    P AE EA         +E  + P +E
Sbjct: 2024 EAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESE 2083

Query: 91   ELPGSHAEPPVPAQG------EAPGEQARDE-----RSDSRAQAVSEDAGGNEGRA-AEA 138
            ++    AE     +       EA GE  + E      ++  AQ  SE     E    A+ 
Sbjct: 2084 DVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQP 2143

Query: 139  EPRALENGDADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEADG 182
            E   +E  DA+  +  + E      +EEE   ++      EA+G
Sbjct: 2144 ESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEG 2187



 Score = 39.7 bits (91), Expect = 0.011
 Identities = 49/157 (31%), Positives = 61/157 (38%), Gaps = 22/157 (14%)

Query: 11   EAAEERAEPGQQQPAAEPPPAEGLLRPAG---PGAPEAA-GTEASSEEVGIAEAGPESEV 66
            E   ER E G Q    E    +G     G   PG  + A G EA   E    EA PESE 
Sbjct: 1795 EGISERGETGGQGSGHEDN-LQGEAAAGGDQDPGQSDGAEGIEAPEAE---GEAQPESEG 1850

Query: 67   RTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSE 126
               P AE +A    +E  + P +E++    AE      GEA  E    E  ++  +   E
Sbjct: 1851 VEAPEAEGDAQE--AEGEAQPESEDVEAPEAE------GEAQPESEDVETPEAEWEVQPE 1902

Query: 127  DAGGNEGRA-AEAEP-----RALENGDADEPSFSDPE 157
              G     A  EA+P      ALE    DEP     E
Sbjct: 1903 SEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAE 1939



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 37/153 (24%), Positives = 53/153 (34%), Gaps = 21/153 (13%)

Query: 18   EPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGI-AEAGPESEVRTEPAAEAEA 76
            + G +QP   P P           A + AG+   SEE  + +  GP+ +   E A+    
Sbjct: 889  QEGTRQPGPTPSPGPNSGASRRSSASQGAGSRGLSEEKTLRSGGGPQGQ---EEASGVSP 945

Query: 77   ASGPSESPSPPAAEELPGSHAEPPVPAQGEA-----------------PGEQARDERSDS 119
            +S P  SP     E L     EP +     A                 PG+    E    
Sbjct: 946  SSLPRSSPEAVVREWLDNIPEEPILMTYELADETTGAAGGGLRGPEVDPGDDHSLEGLGE 1005

Query: 120  RAQAVSEDAGGNEGRAAEAEPRALENGDADEPS 152
             AQA  +   G+ G+  E E   L + D    S
Sbjct: 1006 PAQAGQQSLEGDPGQDPEPEGALLGSSDTGPQS 1038



 Score = 30.4 bits (67), Expect = 6.9
 Identities = 43/157 (27%), Positives = 60/157 (38%), Gaps = 27/157 (17%)

Query: 23  QPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASGPSE 82
           Q +A P  + GL  P G   PE++    + E+ G+  A P +++     AE +A     E
Sbjct: 450 QDSASPASSTGL--PEG-SEPESSCCPRTPED-GVDSASPSAQI----GAERKAGGSLGE 501

Query: 83  SPSPPAAEELPGSHAEPPVPAQGEAPGEQARDER---SDSRAQAVSEDAGGNEG------ 133
            P       L    A    P QG     +AR E    SDS A   S +     G      
Sbjct: 502 DPG------LCIDGAGLGGPEQGGRLTPRARSEEGASSDSSASTGSHEGSSEWGGRPQGC 555

Query: 134 ----RAAEAEPRALENGDADEPSFSDPEDFVDDVSEE 166
               RA  ++  A E GD   P+ S      DD+  E
Sbjct: 556 PGKARAETSQQEASEGGDPASPALSLSSLRSDDLQAE 592



 Score = 30.4 bits (67), Expect = 6.9
 Identities = 21/80 (26%), Positives = 35/80 (43%), Gaps = 6/80 (7%)

Query: 15   ERAEPGQQQPAAEPPPAEGLLRPAGPGA------PEAAGTEASSEEVGIAEAGPESEVRT 68
            +  E G+   +AEP PAEG   P  P +      P A+  ++ S+     E  P + +  
Sbjct: 1428 QEEEAGRASASAEPCPAEGTEEPTEPPSHLSETDPSASERQSGSQLEPGLEKPPGATMMG 1487

Query: 69   EPAAEAEAASGPSESPSPPA 88
            +   +A+   G +E  S  A
Sbjct: 1488 QEHTQAQPTQGAAERSSSVA 1507


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 55/192 (28%), Positives = 65/192 (33%), Gaps = 40/192 (20%)

Query: 8   AVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGA------------------------- 42
           A P A   RA PG   P   P P  G  +PAGPGA                         
Sbjct: 161 AGPAALAARAGPGPG-PGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVN 219

Query: 43  -----------PEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASGPSESPSPPAAEE 91
                      P A GT   +     A A P     + PAA A AA   +  P PPA   
Sbjct: 220 NGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPAT 279

Query: 92  L---PGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDA 148
           L   PG  A PP  A    P   A++  S   A A +  AGG  G + +  P A     A
Sbjct: 280 LARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPA 339

Query: 149 DEPSFSDPEDFV 160
                  P+  V
Sbjct: 340 PGVKAESPKRVV 351



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 41/148 (27%), Positives = 52/148 (35%), Gaps = 16/148 (10%)

Query: 17  AEPGQQQPAAEP-PPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPA---- 71
           A P +  P A P PP  G  RP G G             V    A P +++R  P     
Sbjct: 76  AAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAG 135

Query: 72  ------AEAEAASGPSESPSPPAAEELPGSHAEP----PVPAQGEAPGEQARDERSDSRA 121
                 A A  A+GP  +P+ PA    P + A      P P  G  PG           A
Sbjct: 136 SCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAA 195

Query: 122 QAVSEDAG-GNEGRAAEAEPRALENGDA 148
           Q ++  A   N   AA      + NG A
Sbjct: 196 QTLNGSAALLNSHHAAAPAVSLVNNGPA 223



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 36/112 (32%), Positives = 46/112 (41%), Gaps = 12/112 (10%)

Query: 4   AENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPE 63
           A  V  P AA+     G     A P PA     PAG       G  A++   G+    P+
Sbjct: 294 APAVPPPAAAQNGGSAG-----AAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPK 348

Query: 64  SEVR-TEPAAEAEAASGPSESPS-----PPAAEELPGSHAEPPVPAQGEAPG 109
             V+   PAA+  AASGP+ + +     P     LP   A PP PA G   G
Sbjct: 349 RVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPP-PAPGTPTG 399



 Score = 34.3 bits (77), Expect = 0.48
 Identities = 38/110 (34%), Positives = 42/110 (38%), Gaps = 20/110 (18%)

Query: 10  PEAAEE-----RAEPGQQQPAAEPPPAEGL-LRPAGPGAPEA---------AGTEASSEE 54
           P AA E     RA PG   P    PP+    L PAGP  P A         AG+ A    
Sbjct: 83  PGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPA 142

Query: 55  VGIAEAGPESEVR--TEPAAEAEAAS--GPSESPSP-PAAEELPGSHAEP 99
                AGPE       +PA  A  A+  GP   P P P     PG  A P
Sbjct: 143 AAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGP 192



 Score = 33.5 bits (75), Expect = 0.81
 Identities = 36/123 (29%), Positives = 41/123 (33%), Gaps = 20/123 (16%)

Query: 40  PGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASGPSESPSPPAAEELPG----- 94
           P  PE     A +    +    P       PAA AE A G +  P PPA    PG     
Sbjct: 45  PRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEP-PPAGRARPGGGGPQ 103

Query: 95  -----SHAEPPVPAQGEAPGEQARDERSDSRAQ-----AVSEDAGGNE----GRAAEAEP 140
                S   P VPA    P  + R     S        A +  A G E    G A  A P
Sbjct: 104 RPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGP 163

Query: 141 RAL 143
            AL
Sbjct: 164 AAL 166



 Score = 30.0 bits (66), Expect = 9.0
 Identities = 28/118 (23%), Positives = 37/118 (31%), Gaps = 3/118 (2%)

Query: 7   VAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEV 66
           +  P      A P    P+  PP A     PA    P        +   G     P +  
Sbjct: 238 IQTPPFVGAAAPPAPAAPS--PPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAP 295

Query: 67  RTEPAAEAEAASGPSESPSP-PAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQA 123
              P A A+       +P+P PAA    G   +P   A   AP    + E      QA
Sbjct: 296 AVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQA 353


>gi|23503317 coiled-coil domain containing 96 [Homo sapiens]
          Length = 555

 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 36/115 (31%), Positives = 53/115 (46%), Gaps = 7/115 (6%)

Query: 61  GPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQ-GEAPGEQARDERSDS 119
           G + E      ++ +A+SGP  SP P   E  P    E    +Q G A  EQA   +  +
Sbjct: 15  GGDGESLAARPSKIKASSGPPTSPEPGELESEPEEEEEEQAASQGGTAADEQAEAPKGLT 74

Query: 120 RAQAVSEDAGGNEGRAAEAEPRALENGD--ADEPSFSD----PEDFVDDVSEEEL 168
            A+A  E+  G  GR AE +P   E  +  A+EP+  +    PE+   +   EEL
Sbjct: 75  AAEAAGEEGPGEPGRPAEPQPEPEEPAEVGAEEPAQPEPGAGPEELEAEAGAEEL 129



 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 44/144 (30%), Positives = 59/144 (40%), Gaps = 8/144 (5%)

Query: 10  PEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPE----SE 65
           PE  EE     Q   AA+    E    P G  A EAAG E   E    AE  PE    +E
Sbjct: 47  PEEEEEEQAASQGGTAAD----EQAEAPKGLTAAEAAGEEGPGEPGRPAEPQPEPEEPAE 102

Query: 66  VRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVS 125
           V  E  A+ E  +GP E  +   AEEL  +     V  Q   P  +  +E + +  +A +
Sbjct: 103 VGAEEPAQPEPGAGPEELEAEAGAEELEQAAEGKEVRFQASLPLTRIDEEEAAAAPEAET 162

Query: 126 EDAGGNEGRAAEAEPRALENGDAD 149
           E   G E    E +    E+ + D
Sbjct: 163 ERVEGEEEDKEETQRDGAESKERD 186



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 41/173 (23%), Positives = 66/173 (38%), Gaps = 21/173 (12%)

Query: 4   AENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGP---GAPEAAGTEASSEEVGIAEA 60
           A   A  E   E   P + QP  E P   G   PA P     PE    EA +EE  + +A
Sbjct: 75  AAEAAGEEGPGEPGRPAEPQPEPEEPAEVGAEEPAQPEPGAGPEELEAEAGAEE--LEQA 132

Query: 61  GPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSR 120
               EVR + +           + +P A  E            +GE   E+ ++E     
Sbjct: 133 AEGKEVRFQASLPLTRIDEEEAAAAPEAETE----------RVEGE---EEDKEETQRDG 179

Query: 121 AQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFVDDVSEEELLGDVL 173
           A++   D  G   ++ E   R     + ++  +S+    V  + E++L  D+L
Sbjct: 180 AESKERDGEGRPAKSQEEGKRLYGRDEFEDLEWSEE---VQKLQEQQLRSDLL 229



 Score = 34.3 bits (77), Expect = 0.48
 Identities = 45/210 (21%), Positives = 75/210 (35%), Gaps = 19/210 (9%)

Query: 12  AAEERAEPGQQ-----QPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEV 66
           ++E   +PG +       AA P   +    P  P +PE    E+  EE    +A  +   
Sbjct: 4   SSEHTKDPGGEGGDGESLAARPSKIKASSGP--PTSPEPGELESEPEEEEEEQAASQGGT 61

Query: 67  RTEPAAEAE-----AASGPSESPSPPAAEELPGSHAEPPVPAQGE-----APGEQARDER 116
             +  AEA      A +   E P  P     P    E P     E      PG    +  
Sbjct: 62  AADEQAEAPKGLTAAEAAGEEGPGEPGRPAEPQPEPEEPAEVGAEEPAQPEPGAGPEELE 121

Query: 117 SDSRAQAVSEDAGGNEGRAAEAEP--RALENGDADEPSFSDPEDFVDDVSEEELLGDVLK 174
           +++ A+ + + A G E R   + P  R  E   A  P         ++  +EE   D  +
Sbjct: 122 AEAGAEELEQAAEGKEVRFQASLPLTRIDEEEAAAAPEAETERVEGEEEDKEETQRDGAE 181

Query: 175 DRPQEADGIDSVIVVDNVPQVGPDRLEKLK 204
            + ++ +G  +    +     G D  E L+
Sbjct: 182 SKERDGEGRPAKSQEEGKRLYGRDEFEDLE 211


>gi|193083172 nuclear assembly factor 1 homolog isoform b [Homo
           sapiens]
          Length = 389

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 51/235 (21%), Positives = 88/235 (37%), Gaps = 40/235 (17%)

Query: 19  PGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAAS 78
           P    P + P P       +  G+P+A  T          E  P  E   +P   A AA 
Sbjct: 27  PAAPSPGSAPVPGTQPPLQSFEGSPDAGQT---------VEVKPAGEQPLQPVLNAVAAG 77

Query: 79  GPSESPSPPAAEELPGSHAEPPVPAQ-GEAPGE-QARDERSDSRAQAVSEDAGGNEGRAA 136
            P+  P PPA     G     P  A+   AP   +  D  SDS ++  S+ +  +   ++
Sbjct: 78  TPAPQPQPPAESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSS 137

Query: 137 EAE---------PRALENGDADEPSFSDPEDFVDDVSEEELLGDV--------------- 172
            +          P  L +GD D     + ++F     +E LL ++               
Sbjct: 138 SSSSSSSSCISLPPVLSDGDDDLQIEKENKNFPLKTKDELLLNELPSVEELTIILPEDIE 197

Query: 173 LKDRPQEADGIDSVIVVDNVPQVGPDRLEKL-----KNVIHKIFSKFGKITNDFY 222
           LK     +  I+ +++++++  + P   E +     +    KIF  FG + + FY
Sbjct: 198 LKPLGMVSSIIEQLVIIESMTNLPPVNEETVIFKSDRQAAGKIFEIFGPVAHPFY 252


>gi|193083157 nuclear assembly factor 1 homolog isoform a [Homo
           sapiens]
          Length = 494

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 51/235 (21%), Positives = 88/235 (37%), Gaps = 40/235 (17%)

Query: 19  PGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAAS 78
           P    P + P P       +  G+P+A  T          E  P  E   +P   A AA 
Sbjct: 27  PAAPSPGSAPVPGTQPPLQSFEGSPDAGQT---------VEVKPAGEQPLQPVLNAVAAG 77

Query: 79  GPSESPSPPAAEELPGSHAEPPVPAQ-GEAPGE-QARDERSDSRAQAVSEDAGGNEGRAA 136
            P+  P PPA     G     P  A+   AP   +  D  SDS ++  S+ +  +   ++
Sbjct: 78  TPAPQPQPPAESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSS 137

Query: 137 EAE---------PRALENGDADEPSFSDPEDFVDDVSEEELLGDV--------------- 172
            +          P  L +GD D     + ++F     +E LL ++               
Sbjct: 138 SSSSSSSSCISLPPVLSDGDDDLQIEKENKNFPLKTKDELLLNELPSVEELTIILPEDIE 197

Query: 173 LKDRPQEADGIDSVIVVDNVPQVGPDRLEKL-----KNVIHKIFSKFGKITNDFY 222
           LK     +  I+ +++++++  + P   E +     +    KIF  FG + + FY
Sbjct: 198 LKPLGMVSSIIEQLVIIESMTNLPPVNEETVIFKSDRQAAGKIFEIFGPVAHPFY 252


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 45/164 (27%), Positives = 58/164 (35%), Gaps = 17/164 (10%)

Query: 7    VAVPEAAEERAEPGQQQPAAE-----PPPAEGLLRPAGP-------GAPEAAGTEASSEE 54
            V  P     R E GQ  P+ E     PP  EG+  P GP       G P A+G +    +
Sbjct: 2403 VGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGD 2462

Query: 55   VGIAEAGPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARD 114
             G+   GP  E R EP    E   G      P      PGS  E     +G+      + 
Sbjct: 2463 PGVGLPGPRGE-RGEPGIRGE--DGRPGQEGPRGLTGPPGSRGER--GEKGDVGSAGLKG 2517

Query: 115  ERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPED 158
            ++ DS          G +G   E  PR L+          DP D
Sbjct: 2518 DKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGD 2561



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 44/146 (30%), Positives = 50/146 (34%), Gaps = 15/146 (10%)

Query: 13   AEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGI----AEAGPESEVRT 68
            A    +PG Q P   P P  G   P  PGAP  AG        G+     E GP     T
Sbjct: 2161 AGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLT 2220

Query: 69   EPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQ-GEA--PGEQARDERSDSRAQAVS 125
             P       +G    P PP    L G    P +P Q GE   PG   RD  S       S
Sbjct: 2221 GP-------TGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGS 2273

Query: 126  EDAGGNEGRAAEAEPRALENGDADEP 151
                G+ G      P+  E G    P
Sbjct: 2274 PGVPGSPGLPGPVGPKG-EPGPTGAP 2298



 Score = 38.5 bits (88), Expect = 0.025
 Identities = 34/124 (27%), Positives = 47/124 (37%), Gaps = 15/124 (12%)

Query: 16   RAEPGQQQPAAE-----PPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEP 70
            + +PG + PA E     PP  +G  R    G P AAG    +   G  +AG         
Sbjct: 1757 QGDPGVRGPAGEKGDRGPPGLDG--RSGLDGKPGAAGPSGPNGAAG--KAGDPGRDGLPG 1812

Query: 71   AAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGG 130
                +   GPS    PP     PG   +P +  +   PG+   D R   +  +    A G
Sbjct: 1813 LRGEQGLPGPS---GPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDS---GASG 1866

Query: 131  NEGR 134
             EGR
Sbjct: 1867 REGR 1870



 Score = 36.6 bits (83), Expect = 0.096
 Identities = 37/132 (28%), Positives = 46/132 (34%), Gaps = 20/132 (15%)

Query: 19   PGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVG-IAEAGPESE--VRTEPAAEA- 74
            PG   P   P     L  P  PGAP   G    +   G + + GP  E  +   P  E  
Sbjct: 2376 PGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGI 2435

Query: 75   ---EAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGGN 131
                   GP  S  PP A  L G   +P V   G       R ER +   +       G 
Sbjct: 2436 PGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPG------PRGERGEPGIR-------GE 2482

Query: 132  EGRAAEAEPRAL 143
            +GR  +  PR L
Sbjct: 2483 DGRPGQEGPRGL 2494



 Score = 36.2 bits (82), Expect = 0.13
 Identities = 44/165 (26%), Positives = 53/165 (32%), Gaps = 21/165 (12%)

Query: 10   PEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTE 69
            P     + +PG   P+  P P   L  P   G P   GT    ++    E GP       
Sbjct: 1361 PGLPGRKGDPG---PSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGG 1417

Query: 70   PAAEAEAASGPSESPSPPAAEELPGSHAE--------PPVPAQGEAPGEQ-------ARD 114
             A       G   SP P      PG   E        P +P Q  +PGEQ       A  
Sbjct: 1418 IAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIG 1477

Query: 115  ERSDSRAQAVSEDAG--GNEGRAAEAEPRALENGDADEPSFSDPE 157
             + D        +AG  G  G    A  R L  G A  P    PE
Sbjct: 1478 PKGDRGFPGPLGEAGEKGERGPPGPAGSRGLP-GVAGRPGAKGPE 1521



 Score = 35.0 bits (79), Expect = 0.28
 Identities = 31/121 (25%), Positives = 41/121 (33%), Gaps = 8/121 (6%)

Query: 21   QQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVG-IAEAGPESEVRTEPAAEAEAASG 79
            Q QP A   P +    P  PG     G      +VG +   G + E   + A   +   G
Sbjct: 2586 QGQPGAAGIPGD----PGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKG 2641

Query: 80   PSESPSPPAAEELPGSHAE---PPVPAQGEAPGEQARDERSDSRAQAVSEDAGGNEGRAA 136
                  PP    L G   E   P VP Q  APG++        R         G++G   
Sbjct: 2642 DKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKG 2701

Query: 137  E 137
            E
Sbjct: 2702 E 2702



 Score = 34.7 bits (78), Expect = 0.37
 Identities = 26/93 (27%), Positives = 33/93 (35%), Gaps = 5/93 (5%)

Query: 23   QPAAEPPPAEGLLRPAG----PGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAE-AEAA 77
            +P    PP  GL  P G    PG P  +G        G+     E+     P  + A   
Sbjct: 2208 EPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGK 2267

Query: 78   SGPSESPSPPAAEELPGSHAEPPVPAQGEAPGE 110
             G   SP  P +  LPG       P    APG+
Sbjct: 2268 DGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQ 2300



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 35/144 (24%), Positives = 48/144 (33%), Gaps = 14/144 (9%)

Query: 9    VPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVG----IAEAGPES 64
            +P    +  E G + P  EP     ++   GPG P   G    S   G    + + GP  
Sbjct: 1330 LPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRG 1389

Query: 65   EVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQA-------RDERS 117
                 P    +   G      PP   E   +  EP +P    +PG Q        + E+ 
Sbjct: 1390 PPGL-PGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKG 1448

Query: 118  DSRAQAVSEDAGGNEGRAAEAEPR 141
            DS   A      G  G   E  PR
Sbjct: 1449 DSEDGA--PGLPGQPGSPGEQGPR 1470



 Score = 31.6 bits (70), Expect = 3.1
 Identities = 37/153 (24%), Positives = 50/153 (32%), Gaps = 22/153 (14%)

Query: 15   ERAEPGQQQPAAEPPPA-------EGLLRPAGP-GAPEAAGTEASSEEVGIAEAGPESEV 66
            E+ EPG+    A   PA       +G + PAGP GA    G       V   + GP+ + 
Sbjct: 1532 EKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDP 1591

Query: 67   RTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSE 126
                       +GP     PP      G   +P  P      G + RD     +      
Sbjct: 1592 GDRGPIGLTGRAGPPGDSGPP------GEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPP 1645

Query: 127  DAGGNEGRAAEAEPRAL--------ENGDADEP 151
               G  G+A E   R          E GD  +P
Sbjct: 1646 GDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDP 1678



 Score = 30.0 bits (66), Expect = 9.0
 Identities = 29/102 (28%), Positives = 35/102 (34%), Gaps = 8/102 (7%)

Query: 3    DAENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGP-GAPEAAGTEASSEEVGIAEAG 61
            D+E+ A P    +   PG+Q P   P    G + P G  G P   G      E G    G
Sbjct: 1449 DSEDGA-PGLPGQPGSPGEQGPRGPP----GAIGPKGDRGFPGPLGEAGEKGERG--PPG 1501

Query: 62   PESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPA 103
            P         A    A GP   P P   +   G    P  PA
Sbjct: 1502 PAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPA 1543



 Score = 30.0 bits (66), Expect = 9.0
 Identities = 26/101 (25%), Positives = 38/101 (37%), Gaps = 5/101 (4%)

Query: 10   PEAAEERAEPGQQ-QPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRT 68
            P    ER E G++ +   + PP  GL  P  PG P   G + S +E G   +G +     
Sbjct: 2057 PGERGERGEKGERGEQGRDGPP--GL--PGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGL 2112

Query: 69   EPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPG 109
            + A     ++G            + G   EP    Q   PG
Sbjct: 2113 KGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPG 2153


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 42/145 (28%), Positives = 50/145 (34%), Gaps = 11/145 (7%)

Query: 7    VAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGP----GAPEAAGTEASSEEVGIAEAGP 62
            V +P    ER  PG   PA  P    G + P G     G P   G   S+  VG  E GP
Sbjct: 995  VGMPGQRGERGMPGLPGPAGTP----GKVGPTGATGDKGPPGPVGPPGSNGPVG--EPGP 1048

Query: 63   ESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQ 122
            E     +     + A G       P    LPGS   P  P    APG+  +     SR  
Sbjct: 1049 EGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGP 1108

Query: 123  AVSEDAGGNEGRAAEAEPRALENGD 147
                   G  G      PR  + GD
Sbjct: 1109 IGPPGRAGKRGLPGPQGPRG-DKGD 1132



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 42/159 (26%), Positives = 52/159 (32%), Gaps = 15/159 (9%)

Query: 19  PGQQQPAAEP--PPAEGLLRPAGP-GAPEAAGTEASSEEVGIA-EAGPESE--VRTEPAA 72
           PG   P  E   P   GL+ P G  G P + G    +  VG A   GP+ +  V+ EP  
Sbjct: 806 PGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGE 865

Query: 73  EAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGGNE 132
             +   G + SP P      PG H    VP      G Q     +     A      G  
Sbjct: 866 PGQ--KGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPA 923

Query: 133 GRAAEAEPRALENGDADEPSFSDPEDFVDDVSEEELLGD 171
           G    A       G   EP    P     D      +GD
Sbjct: 924 GAPGPA-------GPLGEPGKEGPPGLRGDPGSHGRVGD 955



 Score = 35.4 bits (80), Expect = 0.21
 Identities = 38/122 (31%), Positives = 43/122 (35%), Gaps = 20/122 (16%)

Query: 10  PEAAEERAEPGQQQPAAEPPPAEGLLRPAGP----GAPEAAGTEASSEEVGIAEAGPESE 65
           P    E  EPGQ+  A  P P +GL    GP    G P   G   +    G A   P S 
Sbjct: 857 PGVKGEPGEPGQKGDAGSPGP-QGLAGSPGPHGPNGVPGLKGGRGTQGPPG-ATGFPGSA 914

Query: 66  VRTEP--AAEAEAASGPSESP---SPPAAEELPGSHAE---------PPVPAQGEAPGEQ 111
            R  P   A A   +GP   P    PP     PGSH           P  P     PGE 
Sbjct: 915 GRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGED 974

Query: 112 AR 113
            +
Sbjct: 975 GQ 976



 Score = 33.9 bits (76), Expect = 0.62
 Identities = 29/91 (31%), Positives = 34/91 (37%), Gaps = 14/91 (15%)

Query: 29  PPAEGLLRPAG----PGAPEAAGTEASSEEVGI----AEAGPESEVRTEPAAEAEAASGP 80
           P + GL  P G    PG P  AG      + G      E GP   V     A      GP
Sbjct: 611 PGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGP 670

Query: 81  SESPSPPAAEELPGSHAEPPVPAQGEAPGEQ 111
              P P   + LPG    P  P +G  PG+Q
Sbjct: 671 ---PGPTGFQGLPGP---PGPPGEGGKPGDQ 695



 Score = 33.5 bits (75), Expect = 0.81
 Identities = 36/148 (24%), Positives = 45/148 (30%), Gaps = 13/148 (8%)

Query: 10   PEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVG-IAEAGPESEVRT 68
            P +A     PG   PA  P PA  L  P   G P   G   S   VG    AGP      
Sbjct: 911  PGSAGRVGPPG---PAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGD 967

Query: 69   EPAAEAEAASGPSESPSPPAAE------ELPGSHAE---PPVPAQGEAPGEQARDERSDS 119
            +     +   GP   P P           +PG   E   P +P     PG+      +  
Sbjct: 968  KGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGD 1027

Query: 120  RAQAVSEDAGGNEGRAAEAEPRALENGD 147
            +         G+ G   E  P      D
Sbjct: 1028 KGPPGPVGPPGSNGPVGEPGPEGPAGND 1055



 Score = 31.2 bits (69), Expect = 4.0
 Identities = 32/126 (25%), Positives = 43/126 (34%), Gaps = 9/126 (7%)

Query: 28  PPPAEGLLRPAGPGAPEAAGTEA-SSEEVGIAEAGPESEVRTEPAAEAEAASGPSESPSP 86
           PP  +G+     PG    AGT     +  GI E G E     + A       GP     P
Sbjct: 757 PPGLQGM-----PGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGP 811

Query: 87  PAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAE-AEPRALEN 145
              +  PG       P     PG +  +  + +   A  +   G  G   E  EP   + 
Sbjct: 812 TGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPG--QK 869

Query: 146 GDADEP 151
           GDA  P
Sbjct: 870 GDAGSP 875



 Score = 30.0 bits (66), Expect = 9.0
 Identities = 29/123 (23%), Positives = 38/123 (30%), Gaps = 7/123 (5%)

Query: 18  EPGQQQPAAEP--PPAEGLLRP-----AGPGAPEAAGTEASSEEVGIAEAGPESEVRTEP 70
           +PG   P   P  P  +GL RP     AG       G++       +   GP      + 
Sbjct: 169 QPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQG 228

Query: 71  AAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGG 130
                  +GP   P  P      GS      P +    GE  R+        A S  A G
Sbjct: 229 QQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARG 288

Query: 131 NEG 133
             G
Sbjct: 289 FPG 291


>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
          Length = 825

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 69/241 (28%), Positives = 104/241 (43%), Gaps = 42/241 (17%)

Query: 4   AENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGI------ 57
           A+ V++ EA  E   P  ++  AE   A   L          A TEAS+EE         
Sbjct: 564 AKGVSIEEAPLELQPPSGEETTAEEASAAIQL---------LAATEASAEEAPAEVQPPP 614

Query: 58  AEAGPESEVRTEPAAEAEAASGP---SESPS---PPAAEELPGSHAEPPVPAQGEAPGEQ 111
           AE  P +EV+  PA EA A   P    E+P+   PP AEE P     PP     EAP E 
Sbjct: 615 AEEAP-AEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAE---EAPAEV 670

Query: 112 ARDERSDSRAQAVS---EDAGGNEGRAAEAEPRALENGDADEPS---FSDPEDFVDDVSE 165
                 ++ A+  S   E+    E  AA   P A ++  A+E S    S P D +  ++E
Sbjct: 671 QPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPA-DDVPAEEASVDKHSPPADLL--LTE 727

Query: 166 EELLGDV--------LKDRPQEADGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKI 217
           E  +G+          +  P++   +++V      PQV      KL +V+ +  +KF ++
Sbjct: 728 EFPIGEASAEVSPPPSEQTPEDEALVENVSTEFQSPQVAGIPAVKLGSVVLEGEAKFEEV 787

Query: 218 T 218
           +
Sbjct: 788 S 788



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 44/155 (28%), Positives = 60/155 (38%), Gaps = 18/155 (11%)

Query: 13  AEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSE-EVGIAEAGPESEVRTE-- 69
           AEE +   Q   A EPP  E       P + E +  EA +E +  +AE     E   E  
Sbjct: 467 AEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQ 526

Query: 70  --PAAEAEAASGPSESPSP----PAAEELPGSHAEPPVPAQG--EAP-------GEQARD 114
              A EA A   P+E+ SP     +AEE P     P        EAP       GE+   
Sbjct: 527 LLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTA 586

Query: 115 ERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDAD 149
           E + +  Q ++      E   AE +P   E   A+
Sbjct: 587 EEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAE 621



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 48/198 (24%), Positives = 71/198 (35%), Gaps = 18/198 (9%)

Query: 1   MQDAENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSE-EVGIAE 59
           + D + +   EA  E A   Q   A E P  E       P   E    EAS+E ++  A 
Sbjct: 421 LADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAAT 480

Query: 60  AGPESEVRTE---PAAEAEAASGPSESPSPPAAEELPGSHAEPPV-------------PA 103
             P  E   E   P +E  +A         P AEE     A   +             PA
Sbjct: 481 EPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPA 540

Query: 104 QGEAP-GEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFVDD 162
           + ++P  E+   E + +  Q+ S      E    E +P + E   A+E S +       +
Sbjct: 541 EAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATE 600

Query: 163 VSEEELLGDVLKDRPQEA 180
            S EE   +V     +EA
Sbjct: 601 ASAEEAPAEVQPPPAEEA 618



 Score = 39.3 bits (90), Expect = 0.015
 Identities = 56/198 (28%), Positives = 75/198 (37%), Gaps = 23/198 (11%)

Query: 5   ENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEA-------------- 50
           E V VP   E  A         EPP  E       P   E A  +A              
Sbjct: 236 EEVTVPVVQEGSAVKKVASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQP 295

Query: 51  SSEEVGIAEAG---PESEVRTE--PAAEAEAASGPSESPSPPAAEELPGSH--AEPPVPA 103
           S+EE   AEA     E+ V+ +  PA EA     P+E   PP+AEE P     AE   P+
Sbjct: 296 STEETPDAEAATAVAENSVKVQPPPAEEAPLVEFPAEI-QPPSAEESPSVELLAEILPPS 354

Query: 104 QGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDAD-EPSFSDPEDFVDD 162
             E+P E+   E     A+         E R+  A+   +E      E +  +    V+ 
Sbjct: 355 AEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEP 414

Query: 163 VSEEELLGDVLKDRPQEA 180
            + EE L DV    P+EA
Sbjct: 415 PTVEETLADVQPLLPEEA 432



 Score = 35.0 bits (79), Expect = 0.28
 Identities = 46/187 (24%), Positives = 71/187 (37%), Gaps = 20/187 (10%)

Query: 4   AENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPE 63
           AE     E   E   P  ++  +E PPAE L     P A ++   E   E    +     
Sbjct: 338 AEESPSVELLAEILPPSAEESPSEEPPAEIL----PPPAEKSPSVELLGEIRSPSAQKAP 393

Query: 64  SEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQA 123
            EV+  P AE      P++   P   E L  +  +P +P   EAP E+AR+ +  +  + 
Sbjct: 394 IEVQPLP-AEGALEEAPAKVEPPTVEETL--ADVQPLLPE--EAPREEARELQLSTAMET 448

Query: 124 VSEDAGGN-----------EGRAAEAEPRALENGDADEPSFSDPEDFVDDVSEEELLGDV 172
            +E+A              E  +AE +  A     ADE          ++ S EE   +V
Sbjct: 449 PAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEV 508

Query: 173 LKDRPQE 179
                +E
Sbjct: 509 QSPLAEE 515



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 29/93 (31%), Positives = 36/93 (38%), Gaps = 6/93 (6%)

Query: 2   QDAENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAG 61
           ++A     P  AEE     Q  PA E P  E L     P A +    EAS ++     + 
Sbjct: 664 EEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDK----HSP 719

Query: 62  PESEVRTE--PAAEAEAASGPSESPSPPAAEEL 92
           P   + TE  P  EA A   P  S   P  E L
Sbjct: 720 PADLLLTEEFPIGEASAEVSPPPSEQTPEDEAL 752


>gi|117938759 GNAS complex locus XLas [Homo sapiens]
          Length = 1037

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 37/150 (24%), Positives = 55/150 (36%), Gaps = 8/150 (5%)

Query: 3   DAENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGP 62
           D ++ A PE  +    P      A     +    PA P  P++            A A P
Sbjct: 401 DPDSGATPEDPDSGTAPADPDSGAFAADPDSGAAPAAPADPDSGAAPD-------APADP 453

Query: 63  ESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQ 122
           +S    +  A+ +A + P E+P+ PAA E   +H  P  P  G      A   R+    +
Sbjct: 454 DSGAAPDAPADPDAGAAP-EAPAAPAAAETRAAHVAPAAPDAGAPTAPAASATRAAQVRR 512

Query: 123 AVSEDAGGNEGRAAEAEPRALENGDADEPS 152
           A S        R     P + E   AD P+
Sbjct: 513 AASAAPASGARRKIHLRPPSPEIQAADPPT 542



 Score = 37.7 bits (86), Expect = 0.043
 Identities = 42/137 (30%), Positives = 53/137 (38%), Gaps = 27/137 (19%)

Query: 24  PAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAE----AGPESEVRTEPAAEAEAASG 79
           PAA  PP   L  P   G+P        S   G +     +GP  E+ + PA   +    
Sbjct: 268 PAANAPP---LWVPGAIGSPSQEAVRPPSNFTGSSPWMEISGPPFEIGSAPAGVDDT--- 321

Query: 80  PSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAE 139
           P    SPP A  L G    PP+   G AP ++ R ER       V E+A   EG A    
Sbjct: 322 PVNMDSPPIA--LDG----PPIKVSG-APDKRERAERPP-----VEEEAAEMEGAA---- 365

Query: 140 PRALENGDADEPSFSDP 156
             A E G    P +  P
Sbjct: 366 -DAAEGGKVPSPGYGSP 381



 Score = 37.0 bits (84), Expect = 0.074
 Identities = 44/161 (27%), Positives = 63/161 (39%), Gaps = 16/161 (9%)

Query: 10  PEAAEERAEPGQQQPAAE----PPPAEGLLRPA-GPGAPEA--AGTEASSEEVGIAEAGP 62
           P+  E    P  ++ AAE       AEG   P+ G G+P A  A  + ++     A A P
Sbjct: 343 PDKRERAERPPVEEEAAEMEGAADAAEGGKVPSPGYGSPAAGAASADTAARAAPAAPADP 402

Query: 63  ESEVRTEPAAEAEAASGPSESP--SPPAAEELPGSHAEPPVPAQGEAPGE----QARDER 116
           +S    E      A + P      + P +   P + A+P   A  +AP +     A D  
Sbjct: 403 DSGATPEDPDSGTAPADPDSGAFAADPDSGAAPAAPADPDSGAAPDAPADPDSGAAPDAP 462

Query: 117 SDSRAQAVSE---DAGGNEGRAAEAEPRALENGDADEPSFS 154
           +D  A A  E        E RAA   P A + G    P+ S
Sbjct: 463 ADPDAGAAPEAPAAPAAAETRAAHVAPAAPDAGAPTAPAAS 503



 Score = 35.0 bits (79), Expect = 0.28
 Identities = 32/113 (28%), Positives = 42/113 (37%), Gaps = 14/113 (12%)

Query: 58  AEAGPESEVRTEPAAEAEAASGPSESPSP-------------PAAEELPGSHAEPPVPAQ 104
           AE  P  E   E    A+AA G  + PSP              AA   P + A+P   A 
Sbjct: 349 AERPPVEEEAAEMEGAADAAEG-GKVPSPGYGSPAAGAASADTAARAAPAAPADPDSGAT 407

Query: 105 GEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPE 157
            E P         DS A A   D+G      A+ +  A  +  AD  S + P+
Sbjct: 408 PEDPDSGTAPADPDSGAFAADPDSGAAPAAPADPDSGAAPDAPADPDSGAAPD 460



 Score = 32.3 bits (72), Expect = 1.8
 Identities = 21/52 (40%), Positives = 24/52 (46%), Gaps = 4/52 (7%)

Query: 59  EAGPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEP-PVPAQGEAPG 109
           E G + E   +P  EA  A+ P   PSP    E    H EP PV   GEA G
Sbjct: 21  EIGEQPE---QPPLEAPGAAAPGAGPSPAEEMETEPPHNEPIPVENDGEACG 69


>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
          Length = 2217

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 39/115 (33%), Positives = 53/115 (46%), Gaps = 13/115 (11%)

Query: 17  AEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPE---SEVRTEPAAE 73
           AE  + +PAA P PA  + +P  PGAP  AG E     VG  E GP+   + V T PA +
Sbjct: 86  AERARGRPAA-PAPAALVAQPGAPGAPADAGPEP----VGTQEPGPDPIAAAVETAPAPD 140

Query: 74  AEAASGPSESPSPPAAEELPGSHAEPPVPAQGEA-PGEQARDERSDSRAQAVSED 127
                GP E  +    +E  G+    P P +      E+  D+  D +A A S D
Sbjct: 141 ----GGPREEAAATVRKEDEGAAEAKPEPGRTRRDEPEEEEDDEDDLKAVATSLD 191



 Score = 38.1 bits (87), Expect = 0.033
 Identities = 31/96 (32%), Positives = 38/96 (39%), Gaps = 24/96 (25%)

Query: 28   PPPAEGLLRPAG-PGAPEAAGTEASSEE----------------VGIAEAGPESEVRTEP 70
            P PA G    AG PG P+   +E  + +                VG+A   P  E     
Sbjct: 1407 PEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPE----- 1461

Query: 71   AAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGE 106
            AA    AS P E   PPA E  P  H+  P PA G+
Sbjct: 1462 AASTRDASAPREPLPPPAPE--PSPHSGTPQPALGQ 1495



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 31/121 (25%), Positives = 45/121 (37%), Gaps = 6/121 (4%)

Query: 19   PGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAAS 78
            P  + PA E P +   L P     PEA+   A  ++   ++  P      +  ++A    
Sbjct: 1317 PVAEHPAPEAPESSPPL-PLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQA---- 1371

Query: 79   GPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEA 138
            GPS  P  P A   P S     +P  G AP      E +   A       G  +G  +E 
Sbjct: 1372 GPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAG-GPGTPQGLTSEL 1430

Query: 139  E 139
            E
Sbjct: 1431 E 1431



 Score = 30.8 bits (68), Expect = 5.3
 Identities = 38/135 (28%), Positives = 54/135 (40%), Gaps = 19/135 (14%)

Query: 10   PEAAEERAEPGQQQPAAEPPP---AEGLLRPAG----PGAPEAAGTEASSEEVGIAE--A 60
            PEA+++ A    Q  + E P    ++ LL  AG    PGAP A    +S     + +  A
Sbjct: 1340 PEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSSPPVTALPQDGA 1399

Query: 61   GPESEVRTEPAAEAEAASGPSESP---------SPPAAEELPGSHAEPPVPAQGEAPGEQ 111
             P +    EPA+   + +G   +P         S P AE      A  P+   G AP   
Sbjct: 1400 APATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPL-VVGLAPCTP 1458

Query: 112  ARDERSDSRAQAVSE 126
            A +  S   A A  E
Sbjct: 1459 APEAASTRDASAPRE 1473



 Score = 30.4 bits (67), Expect = 6.9
 Identities = 31/100 (31%), Positives = 40/100 (40%), Gaps = 25/100 (25%)

Query: 10   PEAAEERAEPGQQQP----AAEPPPAEGLLRPA----GPGAPEAAGTEASSEEVGIAEAG 61
            PEAA  R     ++P    A EP P  G  +PA     P  P A G       V +A   
Sbjct: 1460 PEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGA------VSLAT-- 1511

Query: 62   PESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPV 101
              S++ + P        GP+  P PP+A E  G    P V
Sbjct: 1512 --SQLPSPPL-------GPTVPPQPPSALESDGEGPPPRV 1542


>gi|153070260 myristoylated alanine-rich protein kinase C substrate
           [Homo sapiens]
          Length = 332

 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 44/142 (30%), Positives = 65/142 (45%), Gaps = 14/142 (9%)

Query: 2   QDAENVAVPEAAEERAEPGQQQPAAEPPPAEGL----LRPAGPGAPEAAGTEASSEEVGI 57
           Q ++  A  EAA ER  PG+   A+ P  A G     ++  G  +P AA + A  EE+  
Sbjct: 4   QFSKTAAKGEAAAER--PGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAK-EELQA 60

Query: 58  AEAGPESEVRTEPAAEAEAASGPSES----PSPPAAEELPGSHAEPPVPAQGEA--PGEQ 111
             + P ++ + EPAA    A+ PS +    P+  AA E   S  E   PA+GEA  PG  
Sbjct: 61  NGSAPAAD-KEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSP 119

Query: 112 ARDERSDSRAQAVSEDAGGNEG 133
              E   + A + +      +G
Sbjct: 120 TAAEGEAASAASSTSSPKAEDG 141



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 53/202 (26%), Positives = 72/202 (35%), Gaps = 33/202 (16%)

Query: 8   AVPEAAE----------------ERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEAS 51
           A P AAE                ++ EP      A  P A     PA   APEA  +   
Sbjct: 45  ASPAAAESGAKEELQANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVE 104

Query: 52  SEEVGIAEAGPESEVRTEPAAEAEAASGPSESPSPPAAE-ELPGSHAEPP---------- 100
            E     EA   +E  +  AAE EAAS  S + SP A +   P    E P          
Sbjct: 105 KEAPAEGEA---AEPGSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFK 161

Query: 101 --VPAQGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPED 158
                 G +  +  ++      A+A + + GG +  A  A   A E G A     + P +
Sbjct: 162 KSFKLSGFSFKKNKKEAGEGGEAEAPAAE-GGKDEAAGGAAAAAAEAGAASGEQAAAPGE 220

Query: 159 FVDDVSEEELLGDVLKDRPQEA 180
                 E    GD  + +PQEA
Sbjct: 221 EAAAGEEGAAGGDPQEAKPQEA 242



 Score = 38.9 bits (89), Expect = 0.019
 Identities = 36/110 (32%), Positives = 48/110 (43%), Gaps = 15/110 (13%)

Query: 12  AAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPA 71
           A EE A  G  Q   E  P E  + P  P  P +  T+A+ E   + E   E    +  A
Sbjct: 224 AGEEGAAGGDPQ---EAKPQEAAVAPEKP--PASDETKAAEEPSKVEEKKAEEAGASAAA 278

Query: 72  AEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGE----APGEQARDERS 117
            EA +A+GP    +PP  E  P   AE P  A       AP ++A+ E S
Sbjct: 279 CEAPSAAGPG---APPEQEAAP---AEEPAAAAASSACAAPSQEAQPECS 322



 Score = 38.1 bits (87), Expect = 0.033
 Identities = 36/129 (27%), Positives = 50/129 (38%), Gaps = 12/129 (9%)

Query: 11  EAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTE---------ASSEEVGIAEAG 61
           E  ++ A  G    AAE   A G  + A PG   AAG E         A  +E  +A   
Sbjct: 190 EGGKDEAAGGAAAAAAEAGAASGE-QAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEK 248

Query: 62  PESEVRTEPAAEAEAASGPS--ESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDS 119
           P +   T+ A E          E+ +  AA E P +      P Q  AP E+     + S
Sbjct: 249 PPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASS 308

Query: 120 RAQAVSEDA 128
              A S++A
Sbjct: 309 ACAAPSQEA 317



 Score = 37.4 bits (85), Expect = 0.056
 Identities = 31/104 (29%), Positives = 44/104 (42%), Gaps = 10/104 (9%)

Query: 15  ERAEPGQQQPAAEPPPAEGLLRPAG-PGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAE 73
           + A+P +   A E PPA    + A  P   E    E  +EE G + A  E+     P A 
Sbjct: 235 QEAKPQEAAVAPEKPPASDETKAAEEPSKVE----EKKAEEAGASAAACEAPSAAGPGAP 290

Query: 74  AEAASGPSESPSPPAAEE---LPGSHAEPPVPAQGEAPGEQARD 114
            E  + P+E P+  AA      P   A+P      EAP  +A +
Sbjct: 291 PEQEAAPAEEPAAAAASSACAAPSQEAQP--ECSPEAPPAEAAE 332



 Score = 35.4 bits (80), Expect = 0.21
 Identities = 30/118 (25%), Positives = 46/118 (38%), Gaps = 4/118 (3%)

Query: 37  PAGPGAPE--AAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASGPSESPSPPAAEELPG 94
           PA  G  +  A G  A++ E G A     +    E AA  E A+G     + P  +E   
Sbjct: 187 PAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKP--QEAAV 244

Query: 95  SHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDADEPS 152
           +  +PP   + +A  E ++ E   +     S  A      A    P   E   A+EP+
Sbjct: 245 APEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPA 302



 Score = 33.9 bits (76), Expect = 0.62
 Identities = 28/106 (26%), Positives = 39/106 (36%), Gaps = 10/106 (9%)

Query: 49  EASSEEVGIAEAGPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAP 108
           E    E   AE G +       AA AEA +   E  + P  E   G            A 
Sbjct: 180 EGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEG---------AA 230

Query: 109 GEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDADEPSFS 154
           G   ++ +    A A  +    +E +AAE EP  +E   A+E   S
Sbjct: 231 GGDPQEAKPQEAAVAPEKPPASDETKAAE-EPSKVEEKKAEEAGAS 275


>gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Homo
           sapiens]
          Length = 305

 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 51/184 (27%), Positives = 67/184 (36%), Gaps = 15/184 (8%)

Query: 11  EAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEP 70
           EA E+        PA+ PPP   L     P     A   A+   V +    P       P
Sbjct: 120 EAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAP 179

Query: 71  AAEAEAASGPSESPSP-PAAEELPGSHAEPPVPA-QGEAPGEQARDERSDSRAQAVSEDA 128
           A    AA  P+ +P+P PA    P   A P   A QG   G++ ++  +D     +S   
Sbjct: 180 APAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGIS--- 236

Query: 129 GGNEGRAAEAEPRALENGDA----DEPSFSDPEDFVDDVSEEELLGDVLK--DRPQEADG 182
               GR A     A  NG A      P  SD        + E+  GDV      P  A G
Sbjct: 237 ----GRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPG 292

Query: 183 IDSV 186
           + SV
Sbjct: 293 VGSV 296



 Score = 33.5 bits (75), Expect = 0.81
 Identities = 42/198 (21%), Positives = 72/198 (36%), Gaps = 29/198 (14%)

Query: 3   DAENVAVPEAAEERAEPGQQQPAAEPPP---AEGLLRPAGPGAPEAAGTEASSEEVGIAE 59
           + ++ +VP    E  + G+ +    P P   A  +  P  P A    G E + E++    
Sbjct: 70  EVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQL---P 126

Query: 60  AGPESEVRTEPAAEAEAASGPSESPSP---------------PAAEELPGSHAEP----- 99
           + P     + P      A  P+ +P+P               PA    P     P     
Sbjct: 127 SVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAA 186

Query: 100 PVPAQGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRA--LENGDADEPSFSDPE 157
           P PA   AP        +   A   S + G N+G+  + EP A  L +G +  P+     
Sbjct: 187 PAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQ-EPLADQLHSGISGRPAAGTAA 245

Query: 158 DFVDDVSEEELLGDVLKD 175
              +  + ++L G ++ D
Sbjct: 246 ASANGAAIKKLSGPLISD 263


>gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Homo
           sapiens]
          Length = 305

 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 51/184 (27%), Positives = 67/184 (36%), Gaps = 15/184 (8%)

Query: 11  EAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEP 70
           EA E+        PA+ PPP   L     P     A   A+   V +    P       P
Sbjct: 120 EAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAP 179

Query: 71  AAEAEAASGPSESPSP-PAAEELPGSHAEPPVPA-QGEAPGEQARDERSDSRAQAVSEDA 128
           A    AA  P+ +P+P PA    P   A P   A QG   G++ ++  +D     +S   
Sbjct: 180 APAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGIS--- 236

Query: 129 GGNEGRAAEAEPRALENGDA----DEPSFSDPEDFVDDVSEEELLGDVLK--DRPQEADG 182
               GR A     A  NG A      P  SD        + E+  GDV      P  A G
Sbjct: 237 ----GRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPG 292

Query: 183 IDSV 186
           + SV
Sbjct: 293 VGSV 296



 Score = 33.5 bits (75), Expect = 0.81
 Identities = 42/198 (21%), Positives = 72/198 (36%), Gaps = 29/198 (14%)

Query: 3   DAENVAVPEAAEERAEPGQQQPAAEPPP---AEGLLRPAGPGAPEAAGTEASSEEVGIAE 59
           + ++ +VP    E  + G+ +    P P   A  +  P  P A    G E + E++    
Sbjct: 70  EVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQL---P 126

Query: 60  AGPESEVRTEPAAEAEAASGPSESPSP---------------PAAEELPGSHAEP----- 99
           + P     + P      A  P+ +P+P               PA    P     P     
Sbjct: 127 SVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAA 186

Query: 100 PVPAQGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRA--LENGDADEPSFSDPE 157
           P PA   AP        +   A   S + G N+G+  + EP A  L +G +  P+     
Sbjct: 187 PAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQ-EPLADQLHSGISGRPAAGTAA 245

Query: 158 DFVDDVSEEELLGDVLKD 175
              +  + ++L G ++ D
Sbjct: 246 ASANGAAIKKLSGPLISD 263


>gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo
           sapiens]
          Length = 316

 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 51/184 (27%), Positives = 67/184 (36%), Gaps = 15/184 (8%)

Query: 11  EAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEP 70
           EA E+        PA+ PPP   L     P     A   A+   V +    P       P
Sbjct: 131 EAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAP 190

Query: 71  AAEAEAASGPSESPSP-PAAEELPGSHAEPPVPA-QGEAPGEQARDERSDSRAQAVSEDA 128
           A    AA  P+ +P+P PA    P   A P   A QG   G++ ++  +D     +S   
Sbjct: 191 APAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGIS--- 247

Query: 129 GGNEGRAAEAEPRALENGDA----DEPSFSDPEDFVDDVSEEELLGDVLK--DRPQEADG 182
               GR A     A  NG A      P  SD        + E+  GDV      P  A G
Sbjct: 248 ----GRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPG 303

Query: 183 IDSV 186
           + SV
Sbjct: 304 VGSV 307



 Score = 33.5 bits (75), Expect = 0.81
 Identities = 42/198 (21%), Positives = 72/198 (36%), Gaps = 29/198 (14%)

Query: 3   DAENVAVPEAAEERAEPGQQQPAAEPPP---AEGLLRPAGPGAPEAAGTEASSEEVGIAE 59
           + ++ +VP    E  + G+ +    P P   A  +  P  P A    G E + E++    
Sbjct: 81  EVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQL---P 137

Query: 60  AGPESEVRTEPAAEAEAASGPSESPSP---------------PAAEELPGSHAEP----- 99
           + P     + P      A  P+ +P+P               PA    P     P     
Sbjct: 138 SVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAA 197

Query: 100 PVPAQGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRA--LENGDADEPSFSDPE 157
           P PA   AP        +   A   S + G N+G+  + EP A  L +G +  P+     
Sbjct: 198 PAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQ-EPLADQLHSGISGRPAAGTAA 256

Query: 158 DFVDDVSEEELLGDVLKD 175
              +  + ++L G ++ D
Sbjct: 257 ASANGAAIKKLSGPLISD 274


>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
           [Homo sapiens]
          Length = 916

 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 39/145 (26%), Positives = 57/145 (39%), Gaps = 8/145 (5%)

Query: 7   VAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEV 66
           V++ E  +E AE  +++P AE         P    APE    E   EE    E   E E 
Sbjct: 482 VSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEE---EEGQEEEEE 538

Query: 67  RTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSE 126
             E A   +A  G SE       EE      E     + EA GE+A + + + + +  SE
Sbjct: 539 EDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGE----TEAEAEGEEA-EAKEEKKVEEKSE 593

Query: 127 DAGGNEGRAAEAEPRALENGDADEP 151
           +    E   A+A+    E   +  P
Sbjct: 594 EVATKEELVADAKVEKPEKAKSPVP 618



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 39/142 (27%), Positives = 59/142 (41%), Gaps = 14/142 (9%)

Query: 50  ASSEEVGIA------EAGPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPA 103
           A +EE+ ++      EA  E E   EP AE E  +   +SP    A E+     E     
Sbjct: 475 AITEELAVSMKEEKKEAAEEKE--EEPEAEEEEVAA-KKSPVKATAPEVKEEEGEKEEEE 531

Query: 104 QGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFVDDV 163
             E   E+    +SD   +  SE  G +E    E E    E     E + +  E  V++ 
Sbjct: 532 GQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEK 591

Query: 164 SE-----EELLGDVLKDRPQEA 180
           SE     EEL+ D   ++P++A
Sbjct: 592 SEEVATKEELVADAKVEKPEKA 613


>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
           [Homo sapiens]
          Length = 540

 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 39/145 (26%), Positives = 57/145 (39%), Gaps = 8/145 (5%)

Query: 7   VAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEV 66
           V++ E  +E AE  +++P AE         P    APE    E   EE    E   E E 
Sbjct: 106 VSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEE---EEGQEEEEE 162

Query: 67  RTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSE 126
             E A   +A  G SE       EE      E     + EA GE+A + + + + +  SE
Sbjct: 163 EDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGE----TEAEAEGEEA-EAKEEKKVEEKSE 217

Query: 127 DAGGNEGRAAEAEPRALENGDADEP 151
           +    E   A+A+    E   +  P
Sbjct: 218 EVATKEELVADAKVEKPEKAKSPVP 242



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 39/142 (27%), Positives = 59/142 (41%), Gaps = 14/142 (9%)

Query: 50  ASSEEVGIA------EAGPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPA 103
           A +EE+ ++      EA  E E   EP AE E  +   +SP    A E+     E     
Sbjct: 99  AITEELAVSMKEEKKEAAEEKE--EEPEAEEEEVAA-KKSPVKATAPEVKEEEGEKEEEE 155

Query: 104 QGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFVDDV 163
             E   E+    +SD   +  SE  G +E    E E    E     E + +  E  V++ 
Sbjct: 156 GQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEK 215

Query: 164 SE-----EELLGDVLKDRPQEA 180
           SE     EEL+ D   ++P++A
Sbjct: 216 SEEVATKEELVADAKVEKPEKA 237


>gi|117938310 sine oculis binding protein homolog [Homo sapiens]
          Length = 873

 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 55/196 (28%), Positives = 74/196 (37%), Gaps = 23/196 (11%)

Query: 10  PEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTE 69
           P AAE R   G +     PP A       GPGAP  AG EA++    I         R  
Sbjct: 682 PSAAERRTCGGCRDGHCSPPAAGD----PGPGAP--AGPEAAAACNVIVNG-----TRGA 730

Query: 70  PAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAG 129
            A  A++A  P E P PP     P     P  PA  E   E  ++    S      E A 
Sbjct: 731 AAEGAKSAEPPPEQPPPPPPPAPPKKLLSPEEPAVSEL--ESVKENNCASNCHLDGEAAK 788

Query: 130 GNEGRAAEAEPRALENGDADEPSFSDP--EDFVDDVSEEELLGDVLK--DRPQEADGIDS 185
              G        AL  GD  +P+ ++P  ED    +      G V++   +P E   +  
Sbjct: 789 KLMGE------EALAGGDKSDPNLNNPADEDHAYALRMLPKTGCVIQPVPKPAEKAAMAP 842

Query: 186 VIVVDNVPQVGPDRLE 201
            I+   +   GP+ LE
Sbjct: 843 CIISSPMLSAGPEDLE 858


>gi|140972063 protein phosphatase 1, regulatory subunit 9B [Homo
           sapiens]
          Length = 817

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 50/162 (30%), Positives = 66/162 (40%), Gaps = 22/162 (13%)

Query: 12  AAEERAEPGQQQP-----AAEPPPAEGLLRPAGPGAPEAAG-TEASSEEVGIAEAGPESE 65
           A +ER   GQQ P      A PPP    +R   P   E +G +EA S    + +A    E
Sbjct: 267 AEKERCPAGQQPPQHRVAPARPPPKPREVRKIKPVEVEESGESEAESAPGEVIQA----E 322

Query: 66  VRTEPAAE-----AEAASGPSESPSPPAAEELPGSHAEPPV--PAQGEAPGEQARDERSD 118
           V    A E     A AAS   E P   AA E   +   PP      G AP + A +E  +
Sbjct: 323 VTVHAALENGSTVATAASPAPEEPKAQAAPEKEAAAVAPPERGVGNGRAP-DVAPEEVDE 381

Query: 119 SRAQAVSE----DAGGNEGRAAEAEPRALENGDADEPSFSDP 156
           S+ +  SE    D     G   ++   ALE  D D+    +P
Sbjct: 382 SKKEDFSEADLVDVSAYSGLGEDSAGSALEEDDEDDEEDGEP 423



 Score = 35.4 bits (80), Expect = 0.21
 Identities = 32/125 (25%), Positives = 48/125 (38%), Gaps = 10/125 (8%)

Query: 39  GPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASG--PSESPSPPAAEELPGSH 96
           GPG P AAG    + ++        S V   P     A SG  P+E    PA ++ P   
Sbjct: 227 GPGLPRAAGVPQVNSKL----VSKRSRVFQPPPPPPPAPSGDAPAEKERCPAGQQPPQHR 282

Query: 97  AEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRALENGD----ADEPS 152
             P  P        + +    +   ++ +E A G   +A      ALENG     A  P+
Sbjct: 283 VAPARPPPKPREVRKIKPVEVEESGESEAESAPGEVIQAEVTVHAALENGSTVATAASPA 342

Query: 153 FSDPE 157
             +P+
Sbjct: 343 PEEPK 347


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 32/85 (37%), Positives = 38/85 (44%), Gaps = 4/85 (4%)

Query: 24   PAAEPP-PAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASGPSE 82
            PAA PP P  GL  P+  GAP        S + G+A   P+    T PAA   +  G   
Sbjct: 1175 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKG-APTTPAATPPSPKGGLA 1233

Query: 83   SPSPPAAEELPGSHAEPPVPAQGEA 107
            +PSP  A   P   A PP P  G A
Sbjct: 1234 TPSPKGAPTTPA--ATPPSPKGGPA 1256



 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 32/85 (37%), Positives = 37/85 (43%), Gaps = 4/85 (4%)

Query: 24   PAAEPP-PAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASGPSE 82
            PAA PP P  GL  P   GAP        S + G+A   P+    T PAA   +  G   
Sbjct: 1129 PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKG-APTTPAATPPSPKGGLA 1187

Query: 83   SPSPPAAEELPGSHAEPPVPAQGEA 107
            +PSP  A   P   A PP P  G A
Sbjct: 1188 TPSPKGAPTTPA--ATPPSPKGGLA 1210



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 32/86 (37%), Positives = 39/86 (45%), Gaps = 10/86 (11%)

Query: 24   PAAEPP-PAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASG--- 79
            PAA PP P  GL  P+  GAP        S + G+A   P+    T PAA   +  G   
Sbjct: 1198 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKG-APTTPAATPPSPKGGPA 1256

Query: 80   ---PSESPSPPAA--EELPGSHAEPP 100
               P  +P+PPAA    L G  A PP
Sbjct: 1257 TPPPKGAPTPPAATPPSLKGGLATPP 1282



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 31/85 (36%), Positives = 36/85 (42%), Gaps = 4/85 (4%)

Query: 24   PAAEPP-PAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASGPSE 82
            PAA PP P  GL  P   GAP        S + G+A   P+    T PAA   +  G   
Sbjct: 1106 PAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKG-APTTPAATPPSPKGGLA 1164

Query: 83   SPSPPAAEELPGSHAEPPVPAQGEA 107
            +P P  A   P   A PP P  G A
Sbjct: 1165 TPPPKGAPTTPA--ATPPSPKGGLA 1187



 Score = 38.9 bits (89), Expect = 0.019
 Identities = 30/85 (35%), Positives = 35/85 (41%), Gaps = 4/85 (4%)

Query: 24   PAAEPP-PAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASGPSE 82
            PAA PP P  G   P+  GAP        S + G+A   P     T PAA   +  G   
Sbjct: 1083 PAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLA-TPPHKGAPTTPAATPPSPKGGLA 1141

Query: 83   SPSPPAAEELPGSHAEPPVPAQGEA 107
            +P P  A   P   A PP P  G A
Sbjct: 1142 TPPPKGAPTTPA--ATPPSPKGGLA 1164



 Score = 36.6 bits (83), Expect = 0.096
 Identities = 32/104 (30%), Positives = 40/104 (38%), Gaps = 20/104 (19%)

Query: 24   PAAEPPPAEG-LLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASG--- 79
            PAA PP  +G L  P   GAP  A     S + G A + P+    T PAA   +  G   
Sbjct: 1267 PAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKG-APTPPAATPPSPKGSPG 1325

Query: 80   ---PSESPSPPAAEE------------LPGSHAEPPVPAQGEAP 108
               P  +P+PPA                P S   P  P+  E P
Sbjct: 1326 TPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGP 1369



 Score = 35.4 bits (80), Expect = 0.21
 Identities = 32/109 (29%), Positives = 40/109 (36%), Gaps = 12/109 (11%)

Query: 9    VPEAAEERAEPGQQQPAAEPP-PAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVR 67
            +P +   +  P    PAA PP P  G   P+   AP        S + G A   P+    
Sbjct: 930  IPASPSPKGAP--TPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKG-AP 986

Query: 68   TEPAAEAEAASGPSESPSPPAAEELP--------GSHAEPPVPAQGEAP 108
            T PAA   +  G   +PSP  A   P        GS A  P P     P
Sbjct: 987  TPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTP 1035



 Score = 34.7 bits (78), Expect = 0.37
 Identities = 28/81 (34%), Positives = 34/81 (41%), Gaps = 5/81 (6%)

Query: 24   PAAEPP-PAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASG-PS 81
            PAA PP P  G   P+  GAP        S + G A   P+    T PA    +  G P+
Sbjct: 966  PAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKG-APTPPAVTPPSPKGSPA 1024

Query: 82   ESPSPPAAEELPGSHAEPPVP 102
             +P P  A   P   A PP P
Sbjct: 1025 ATPFPKGASTPPA--ATPPSP 1043



 Score = 34.7 bits (78), Expect = 0.37
 Identities = 25/92 (27%), Positives = 34/92 (36%), Gaps = 5/92 (5%)

Query: 17   AEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGP----ESEVRTEPAA 72
            A P   + +   PP +G   P     P   GT         ++ GP      E  T PAA
Sbjct: 1315 ATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAA 1374

Query: 73   EAEAASGPSES-PSPPAAEELPGSHAEPPVPA 103
                  GP+ + PSP     +P    +P  PA
Sbjct: 1375 TPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPA 1406



 Score = 33.9 bits (76), Expect = 0.62
 Identities = 28/87 (32%), Positives = 35/87 (40%), Gaps = 9/87 (10%)

Query: 28  PPPAEGLLRPAGPGAPEAAGTEASSEEV-------GIAEAGPESEVRTEPAAEAEAASGP 80
           P P EG   PA   AP  + T +S ++        GI  +       T PAA   +  G 
Sbjct: 894 PFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGG 953

Query: 81  SESPSPPAAEELPGSHAEPPVPAQGEA 107
             +PSP  A   P   A PP P  G A
Sbjct: 954 PATPSPKWAPTPPA--ATPPSPKGGPA 978



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 27/82 (32%), Positives = 32/82 (39%), Gaps = 3/82 (3%)

Query: 26   AEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASGPSESPS 85
            A P P      P+  GAP        S + G A   P+    T PAA   +  G   +PS
Sbjct: 923  ATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKW-APTPPAATPPSPKGGPATPS 981

Query: 86   PPAAEELPGSHAEPPVPAQGEA 107
            P  A   P   A PP P  G A
Sbjct: 982  PKGAPTPPA--ATPPSPKGGPA 1001



 Score = 31.6 bits (70), Expect = 3.1
 Identities = 26/89 (29%), Positives = 38/89 (42%), Gaps = 15/89 (16%)

Query: 19   PGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAAS 78
            P  ++  A P P E    PA P + EA+   A +         P+ E+   PA  + +  
Sbjct: 1556 PSPKKTPAIPTPKEA---PATPSSKEASSPPAVTPSTYKGAPSPK-ELLIPPAVTSPS-- 1609

Query: 79   GPSESPSPPAAEELPGSHAEPPVPAQGEA 107
             P E+P+PPA          PP P +G A
Sbjct: 1610 -PKEAPTPPA--------VTPPSPEKGPA 1629



 Score = 30.0 bits (66), Expect = 9.0
 Identities = 41/147 (27%), Positives = 50/147 (34%), Gaps = 23/147 (15%)

Query: 24   PAAEPPPAEGLLRPAGPGAPEAAG-------TEASSEEVGIAEAGPESEVRTEPAAEAEA 76
            PAA PP  +G     GP  P   G       T  S +    A   P+    T PAA   +
Sbjct: 989  PAATPPSPKG-----GPATPSPKGAPTPPAVTPPSPKGSPAATPFPKG-ASTPPAATPPS 1042

Query: 77   ASG-------PSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAG 129
              G       P  +P+ PAA  LP     P  P+   AP   A    S     A     G
Sbjct: 1043 PKGSPAATPLPKGAPTTPAA-TLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKG 1101

Query: 130  GNEGRAAEAEPRALENGDADEPSFSDP 156
                 A  A P + + G A  P    P
Sbjct: 1102 APMPPA--ATPPSPKGGLATPPHKGAP 1126


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 46/160 (28%), Positives = 51/160 (31%), Gaps = 16/160 (10%)

Query: 12  AAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPA 71
           AA  R   GQ  PA  P P      P  PGAP A G           EAGP      E A
Sbjct: 340 AAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKG-----------EAGPTGARGPEGA 388

Query: 72  AEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGGN 131
                  G   SP P  A   PG+   P       APG          R     + A G 
Sbjct: 389 QGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGP 448

Query: 132 EG-RAAEAEPRAL----ENGDADEPSFSDPEDFVDDVSEE 166
            G +    EP       E G   EP  + P+       EE
Sbjct: 449 LGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEE 488



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 40/158 (25%), Positives = 53/158 (33%), Gaps = 20/158 (12%)

Query: 12  AAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEA----------G 61
           +A  R  PG++     P PA     P   G P A G +  + + G A A          G
Sbjct: 814 SAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPG 873

Query: 62  PESEVRTEPAAEAEAASGPSESPSPPAAEEL---PGSHAEPPVPAQGEAPGEQARDERSD 118
           P+          A  A GP  +   P A      PGS+  P  P     PG   +D    
Sbjct: 874 PQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPG---PPGPSGKDGPKG 930

Query: 119 SRAQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDP 156
           +R  +      G  G    A P     G+  EP    P
Sbjct: 931 ARGDSGPPGRAGEPGLQGPAGP----PGEKGEPGDDGP 964



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 43/145 (29%), Positives = 57/145 (39%), Gaps = 21/145 (14%)

Query: 19  PGQQQPAAEP--PPAEGLLRPAGPGAPEAA----GTEASSEEVGIAEAGPESEVRTEPAA 72
           PG +  A  P    A G   P GP  P+ A    G +  + E GIA    E   + EP  
Sbjct: 416 PGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGP 475

Query: 73  EAEAASGPSESPSPPAAEELPGSHAEP----PVPAQGE--APGEQARDERSDSRAQAVSE 126
                +GP  +P P   E   G+  EP    P+   GE  APG +    +      A  +
Sbjct: 476 -----AGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQD---GLAGPK 527

Query: 127 DAGGNEGRAAEAEPRALENGDADEP 151
            A G  G +  A P+   NGD   P
Sbjct: 528 GAPGERGPSGLAGPKG-ANGDPGRP 551



 Score = 39.7 bits (91), Expect = 0.011
 Identities = 38/143 (26%), Positives = 52/143 (36%), Gaps = 8/143 (5%)

Query: 4   AENVAVPEAAEERAEPGQQQPAAEPPP--AEGLLRPAGPGAPEAAGTEASSEEVGIAEAG 61
           A  +A P+   +R + G++ P   P      GL  P GP  P  AG      EVG     
Sbjct: 757 AAGIAGPKG--DRGDVGEKGPEGAPGKDGGRGLTGPIGPPGP--AGANGEKGEVGPPGPA 812

Query: 62  PESEVRTEPAAEAEAA-SGPSESPSPPAAEELPGSHAEPPVPAQ-GEAPGEQARDERSDS 119
             +  R  P    E    GP+    PP A+  PG+  E     Q G+A     +      
Sbjct: 813 GSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAP 872

Query: 120 RAQAVSEDAGGNEGRAAEAEPRA 142
             Q  +   G    R A+  P A
Sbjct: 873 GPQGPTGVTGPKGARGAQGPPGA 895



 Score = 38.9 bits (89), Expect = 0.019
 Identities = 41/152 (26%), Positives = 54/152 (35%), Gaps = 17/152 (11%)

Query: 7    VAVPEAAEERAEPGQQQPAAEP-----PPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAG 61
            V +P    ER  PG   P+ EP     P A G   P GP  P      A        E G
Sbjct: 983  VGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPA-------GEPG 1035

Query: 62   PESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRA 121
             E     +     + A+G         A   PG+   P  P      G+Q   +R ++ A
Sbjct: 1036 REGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG--DRGEAGA 1093

Query: 122  QAVSEDAG--GNEGRAAEAEPRALENGDADEP 151
            Q     +G  G  G      PR  + G+A EP
Sbjct: 1094 QGPMGPSGPAGARGIQGPQGPRG-DKGEAGEP 1124



 Score = 38.5 bits (88), Expect = 0.025
 Identities = 42/139 (30%), Positives = 51/139 (36%), Gaps = 27/139 (19%)

Query: 20  GQQQPAAEPPPAEGLLRPAGP-GAPEAAGTE----ASSEEVGIAEAGPESEV-----RTE 69
           G+Q P  EP PA       GP GAP  AG E    A  E  G+   GP  E      R  
Sbjct: 465 GEQGPKGEPGPA-------GPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGF 517

Query: 70  PAAE-------AEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQ 122
           P  +       A    GPS    P  A   PG   EP +P    A G   R   +  + +
Sbjct: 518 PGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPG---ARGLTGRPGDAGPQGK 574

Query: 123 AVSEDAGGNEGRAAEAEPR 141
                A G +GR     P+
Sbjct: 575 VGPSGAPGEDGRPGPPGPQ 593



 Score = 36.2 bits (82), Expect = 0.13
 Identities = 39/142 (27%), Positives = 51/142 (35%), Gaps = 9/142 (6%)

Query: 13  AEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAA 72
           A  +  PG++ P+    P      P  PG P   G    +   G  +AGP+ +V    A 
Sbjct: 524 AGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPG--DAGPQGKVGPSGAP 581

Query: 73  EAEAASGPSESPSPPAAEELPGSHAEP-PVPAQGE--APGEQARDERSDSRAQAVSEDAG 129
             +   GP   P P  A   PG    P P  A GE    GE+        R     +   
Sbjct: 582 GEDGRPGP---PGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGET 638

Query: 130 GNEGRAAEAEPRALENGDADEP 151
           G  G    A P A E G+   P
Sbjct: 639 GAAGPPGPAGP-AGERGEQGAP 659



 Score = 35.0 bits (79), Expect = 0.28
 Identities = 38/143 (26%), Positives = 50/143 (34%), Gaps = 8/143 (5%)

Query: 10   PEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGI-AEAGPESEVRT 68
            P AA     PG       P P     +    GA   +G    + E G+   AGP  E + 
Sbjct: 899  PGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGE-KG 957

Query: 69   EPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDA 128
            EP  +     GPS +  PP  + L G      +P Q    G       S    +  +  A
Sbjct: 958  EPGDD-----GPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGA 1012

Query: 129  GGNEGRAAEAEPRALENGDADEP 151
             G+ G      P  L  G A EP
Sbjct: 1013 SGDRGPPGPVGPPGL-TGPAGEP 1034



 Score = 34.3 bits (77), Expect = 0.48
 Identities = 35/137 (25%), Positives = 49/137 (35%), Gaps = 18/137 (13%)

Query: 10   PEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTE 69
            P A+ +R  PG   P     PA    R   PGA    G + +        AG + +    
Sbjct: 1010 PGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGA--------AGVKGDRGET 1061

Query: 70   PAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAG 129
             A  A  A GP  SP P       G         +GEA  +        + A+ +    G
Sbjct: 1062 GAVGAPGAPGPPGSPGPAGPTGKQGD--------RGEAGAQGPMGPSGPAGARGIQGPQG 1113

Query: 130  --GNEGRAAEAEPRALE 144
              G++G A E   R L+
Sbjct: 1114 PRGDKGEAGEPGERGLK 1130



 Score = 33.9 bits (76), Expect = 0.62
 Identities = 31/97 (31%), Positives = 35/97 (36%), Gaps = 14/97 (14%)

Query: 19  PGQQQPAAEPPPA--EGLLRPAGPGAPEAAGTEASSEEVGIA----EAGPESEVRTEPAA 72
           PG +    EP  A  +GL     PGAP   G      E G A     AGP  E   + A 
Sbjct: 605 PGPKGANGEPGKAGEKGL-----PGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAP 659

Query: 73  EAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPG 109
                 G    P PP     PG      VP +  APG
Sbjct: 660 GPSGFQGLPGPPGPPGEGGKPGDQG---VPGEAGAPG 693



 Score = 33.5 bits (75), Expect = 0.81
 Identities = 33/130 (25%), Positives = 43/130 (33%), Gaps = 12/130 (9%)

Query: 16  RAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAE 75
           R  PG   PA  P P      P  PG P  +G             GP  +   +  A   
Sbjct: 209 RGPPG---PAGAPGPQGFQGNPGEPGEPGVSGPMGPR-----GPPGPPGKPGDDGEAGKP 260

Query: 76  AASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAG--GNEG 133
             +G    P P  A   PG+   P V      PG      + ++ A  V  ++G  G  G
Sbjct: 261 GKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDG--AKGEAGAPGVKGESGSPGENG 318

Query: 134 RAAEAEPRAL 143
                 PR L
Sbjct: 319 SPGPMGPRGL 328



 Score = 32.3 bits (72), Expect = 1.8
 Identities = 47/172 (27%), Positives = 52/172 (30%), Gaps = 21/172 (12%)

Query: 15   ERAEPGQQQP--AAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEA-GPESEVRTEPA 71
            E+ EPG   P  A  PP  +GL    G       G      E G     GP  E   + A
Sbjct: 955  EKGEPGDDGPSGAEGPPGPQGLAGQRG-----IVGLPGQRGERGFPGLPGPSGEPGKQGA 1009

Query: 72   AEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGGN 131
              A    GP     PP    L G   EP       A G   RD      A  V  D G  
Sbjct: 1010 PGASGDRGPPGPVGPPG---LTGPAGEPGREGSPGADGPPGRD-----GAAGVKGDRGET 1061

Query: 132  EGRAAEAEPRALENGDADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEADGI 183
                A   P     G    P  + P     D  E    G +    P  A GI
Sbjct: 1062 GAVGAPGAP-----GPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGI 1108



 Score = 31.2 bits (69), Expect = 4.0
 Identities = 32/154 (20%), Positives = 50/154 (32%), Gaps = 15/154 (9%)

Query: 11  EAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEP 70
           + A    +PG +    EP   + ++ P GP  P+    E         + G + E     
Sbjct: 92  DLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPR----GDRGDKGEKGAPG 147

Query: 71  AAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSE---- 126
               +   G   +P PP     PG    P +     A      DE++      V +    
Sbjct: 148 PRGRDGEPGTPGNPGPPGP---PGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMG 204

Query: 127 --DAGGNEGRAAEAEPRALEN--GDADEPSFSDP 156
                G  G A    P+  +   G+  EP  S P
Sbjct: 205 PMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGP 238


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 46/160 (28%), Positives = 51/160 (31%), Gaps = 16/160 (10%)

Query: 12  AAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPA 71
           AA  R   GQ  PA  P P      P  PGAP A G           EAGP      E A
Sbjct: 271 AAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKG-----------EAGPTGARGPEGA 319

Query: 72  AEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGGN 131
                  G   SP P  A   PG+   P       APG          R     + A G 
Sbjct: 320 QGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGP 379

Query: 132 EG-RAAEAEPRAL----ENGDADEPSFSDPEDFVDDVSEE 166
            G +    EP       E G   EP  + P+       EE
Sbjct: 380 LGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEE 419



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 40/158 (25%), Positives = 53/158 (33%), Gaps = 20/158 (12%)

Query: 12  AAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEA----------G 61
           +A  R  PG++     P PA     P   G P A G +  + + G A A          G
Sbjct: 745 SAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPG 804

Query: 62  PESEVRTEPAAEAEAASGPSESPSPPAAEEL---PGSHAEPPVPAQGEAPGEQARDERSD 118
           P+          A  A GP  +   P A      PGS+  P  P     PG   +D    
Sbjct: 805 PQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPG---PPGPSGKDGPKG 861

Query: 119 SRAQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDP 156
           +R  +      G  G    A P     G+  EP    P
Sbjct: 862 ARGDSGPPGRAGEPGLQGPAGP----PGEKGEPGDDGP 895



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 43/145 (29%), Positives = 57/145 (39%), Gaps = 21/145 (14%)

Query: 19  PGQQQPAAEP--PPAEGLLRPAGPGAPEAA----GTEASSEEVGIAEAGPESEVRTEPAA 72
           PG +  A  P    A G   P GP  P+ A    G +  + E GIA    E   + EP  
Sbjct: 347 PGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGP 406

Query: 73  EAEAASGPSESPSPPAAEELPGSHAEP----PVPAQGE--APGEQARDERSDSRAQAVSE 126
                +GP  +P P   E   G+  EP    P+   GE  APG +    +      A  +
Sbjct: 407 -----AGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQD---GLAGPK 458

Query: 127 DAGGNEGRAAEAEPRALENGDADEP 151
            A G  G +  A P+   NGD   P
Sbjct: 459 GAPGERGPSGLAGPKG-ANGDPGRP 482



 Score = 39.7 bits (91), Expect = 0.011
 Identities = 38/143 (26%), Positives = 52/143 (36%), Gaps = 8/143 (5%)

Query: 4   AENVAVPEAAEERAEPGQQQPAAEPPP--AEGLLRPAGPGAPEAAGTEASSEEVGIAEAG 61
           A  +A P+   +R + G++ P   P      GL  P GP  P  AG      EVG     
Sbjct: 688 AAGIAGPKG--DRGDVGEKGPEGAPGKDGGRGLTGPIGPPGP--AGANGEKGEVGPPGPA 743

Query: 62  PESEVRTEPAAEAEAA-SGPSESPSPPAAEELPGSHAEPPVPAQ-GEAPGEQARDERSDS 119
             +  R  P    E    GP+    PP A+  PG+  E     Q G+A     +      
Sbjct: 744 GSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAP 803

Query: 120 RAQAVSEDAGGNEGRAAEAEPRA 142
             Q  +   G    R A+  P A
Sbjct: 804 GPQGPTGVTGPKGARGAQGPPGA 826



 Score = 38.9 bits (89), Expect = 0.019
 Identities = 41/152 (26%), Positives = 54/152 (35%), Gaps = 17/152 (11%)

Query: 7    VAVPEAAEERAEPGQQQPAAEP-----PPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAG 61
            V +P    ER  PG   P+ EP     P A G   P GP  P      A        E G
Sbjct: 914  VGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPA-------GEPG 966

Query: 62   PESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRA 121
             E     +     + A+G         A   PG+   P  P      G+Q   +R ++ A
Sbjct: 967  REGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG--DRGEAGA 1024

Query: 122  QAVSEDAG--GNEGRAAEAEPRALENGDADEP 151
            Q     +G  G  G      PR  + G+A EP
Sbjct: 1025 QGPMGPSGPAGARGIQGPQGPRG-DKGEAGEP 1055



 Score = 38.5 bits (88), Expect = 0.025
 Identities = 42/139 (30%), Positives = 51/139 (36%), Gaps = 27/139 (19%)

Query: 20  GQQQPAAEPPPAEGLLRPAGP-GAPEAAGTE----ASSEEVGIAEAGPESEV-----RTE 69
           G+Q P  EP PA       GP GAP  AG E    A  E  G+   GP  E      R  
Sbjct: 396 GEQGPKGEPGPA-------GPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGF 448

Query: 70  PAAE-------AEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQ 122
           P  +       A    GPS    P  A   PG   EP +P    A G   R   +  + +
Sbjct: 449 PGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPG---ARGLTGRPGDAGPQGK 505

Query: 123 AVSEDAGGNEGRAAEAEPR 141
                A G +GR     P+
Sbjct: 506 VGPSGAPGEDGRPGPPGPQ 524



 Score = 36.2 bits (82), Expect = 0.13
 Identities = 39/142 (27%), Positives = 51/142 (35%), Gaps = 9/142 (6%)

Query: 13  AEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAA 72
           A  +  PG++ P+    P      P  PG P   G    +   G  +AGP+ +V    A 
Sbjct: 455 AGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPG--DAGPQGKVGPSGAP 512

Query: 73  EAEAASGPSESPSPPAAEELPGSHAEP-PVPAQGE--APGEQARDERSDSRAQAVSEDAG 129
             +   GP   P P  A   PG    P P  A GE    GE+        R     +   
Sbjct: 513 GEDGRPGP---PGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGET 569

Query: 130 GNEGRAAEAEPRALENGDADEP 151
           G  G    A P A E G+   P
Sbjct: 570 GAAGPPGPAGP-AGERGEQGAP 590



 Score = 35.0 bits (79), Expect = 0.28
 Identities = 38/143 (26%), Positives = 50/143 (34%), Gaps = 8/143 (5%)

Query: 10  PEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGI-AEAGPESEVRT 68
           P AA     PG       P P     +    GA   +G    + E G+   AGP  E + 
Sbjct: 830 PGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGE-KG 888

Query: 69  EPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDA 128
           EP  +     GPS +  PP  + L G      +P Q    G       S    +  +  A
Sbjct: 889 EPGDD-----GPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGA 943

Query: 129 GGNEGRAAEAEPRALENGDADEP 151
            G+ G      P  L  G A EP
Sbjct: 944 SGDRGPPGPVGPPGL-TGPAGEP 965



 Score = 34.3 bits (77), Expect = 0.48
 Identities = 35/137 (25%), Positives = 49/137 (35%), Gaps = 18/137 (13%)

Query: 10   PEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTE 69
            P A+ +R  PG   P     PA    R   PGA    G + +        AG + +    
Sbjct: 941  PGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGA--------AGVKGDRGET 992

Query: 70   PAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAG 129
             A  A  A GP  SP P       G         +GEA  +        + A+ +    G
Sbjct: 993  GAVGAPGAPGPPGSPGPAGPTGKQGD--------RGEAGAQGPMGPSGPAGARGIQGPQG 1044

Query: 130  --GNEGRAAEAEPRALE 144
              G++G A E   R L+
Sbjct: 1045 PRGDKGEAGEPGERGLK 1061



 Score = 33.9 bits (76), Expect = 0.62
 Identities = 31/97 (31%), Positives = 35/97 (36%), Gaps = 14/97 (14%)

Query: 19  PGQQQPAAEPPPA--EGLLRPAGPGAPEAAGTEASSEEVGIA----EAGPESEVRTEPAA 72
           PG +    EP  A  +GL     PGAP   G      E G A     AGP  E   + A 
Sbjct: 536 PGPKGANGEPGKAGEKGL-----PGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAP 590

Query: 73  EAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPG 109
                 G    P PP     PG      VP +  APG
Sbjct: 591 GPSGFQGLPGPPGPPGEGGKPGDQG---VPGEAGAPG 624



 Score = 33.5 bits (75), Expect = 0.81
 Identities = 33/130 (25%), Positives = 43/130 (33%), Gaps = 12/130 (9%)

Query: 16  RAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAE 75
           R  PG   PA  P P      P  PG P  +G             GP  +   +  A   
Sbjct: 140 RGPPG---PAGAPGPQGFQGNPGEPGEPGVSGPMGPR-----GPPGPPGKPGDDGEAGKP 191

Query: 76  AASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAG--GNEG 133
             +G    P P  A   PG+   P V      PG      + ++ A  V  ++G  G  G
Sbjct: 192 GKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDG--AKGEAGAPGVKGESGSPGENG 249

Query: 134 RAAEAEPRAL 143
                 PR L
Sbjct: 250 SPGPMGPRGL 259



 Score = 32.3 bits (72), Expect = 1.8
 Identities = 47/172 (27%), Positives = 52/172 (30%), Gaps = 21/172 (12%)

Query: 15   ERAEPGQQQP--AAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEA-GPESEVRTEPA 71
            E+ EPG   P  A  PP  +GL    G       G      E G     GP  E   + A
Sbjct: 886  EKGEPGDDGPSGAEGPPGPQGLAGQRG-----IVGLPGQRGERGFPGLPGPSGEPGKQGA 940

Query: 72   AEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGGN 131
              A    GP     PP    L G   EP       A G   RD      A  V  D G  
Sbjct: 941  PGASGDRGPPGPVGPPG---LTGPAGEPGREGSPGADGPPGRD-----GAAGVKGDRGET 992

Query: 132  EGRAAEAEPRALENGDADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEADGI 183
                A   P     G    P  + P     D  E    G +    P  A GI
Sbjct: 993  GAVGAPGAP-----GPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGI 1039



 Score = 30.4 bits (67), Expect = 6.9
 Identities = 31/147 (21%), Positives = 48/147 (32%), Gaps = 15/147 (10%)

Query: 18  EPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAA 77
           +PG +    EP   + ++ P GP  P+    E         + G + E         +  
Sbjct: 30  QPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPR----GDRGDKGEKGAPGPRGRDGE 85

Query: 78  SGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSE------DAGGN 131
            G   +P PP     PG    P +     A      DE++      V +         G 
Sbjct: 86  PGTPGNPGPPGP---PGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGP 142

Query: 132 EGRAAEAEPRALEN--GDADEPSFSDP 156
            G A    P+  +   G+  EP  S P
Sbjct: 143 PGPAGAPGPQGFQGNPGEPGEPGVSGP 169


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 51/174 (29%), Positives = 72/174 (41%), Gaps = 16/174 (9%)

Query: 7   VAVPEAAEERA-EPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEA-GPE- 63
           V  PE A+  A E  +  P A+ P  E    PA   +PE A + A  E    AEA  PE 
Sbjct: 544 VKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEK 603

Query: 64  --SEVRTEPAAEAEA-------ASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARD 114
             S V+ E  + AEA       A  P+E  SP  A+      A+ P  A+     E    
Sbjct: 604 AKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSP 663

Query: 115 ERSDS--RAQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFVDDVSEE 166
           E++ S  +A+A S +   +  +A    P   ++   +E     PE     V EE
Sbjct: 664 EKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEA--KSPEKAKSPVKEE 715



 Score = 39.7 bits (91), Expect = 0.011
 Identities = 43/180 (23%), Positives = 72/180 (40%), Gaps = 13/180 (7%)

Query: 1   MQDAENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEA 60
           ++  E + V E +E+     ++Q   E    E +       A E  G E    E   AE 
Sbjct: 438 VKSEEKIKVVEKSEKETVIVEEQ-TEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEG 496

Query: 61  GPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSR 120
           G E E ++ PA EA  AS   E+ SP   E    + A+ P   + ++P E    E++ S 
Sbjct: 497 G-EEETKSPPAEEA--ASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSP 553

Query: 121 AQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEA 180
           A+         E   +  E ++ E  +A  P+     +     ++EE         P++A
Sbjct: 554 AK---------EEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKA 604



 Score = 36.6 bits (83), Expect = 0.096
 Identities = 42/163 (25%), Positives = 63/163 (38%), Gaps = 26/163 (15%)

Query: 5   ENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPES 64
           E V  PE A+   +   + P  E P  E +  P           E   +EV + E   ++
Sbjct: 791 EEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKE--------EEKPQEVKVKEPPKKA 842

Query: 65  EVRTEPAA-------EAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERS 117
           E    PA        +++    P +    P  EE      E P  ++ EA  E+A D++ 
Sbjct: 843 EEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKK 902

Query: 118 ----DSRAQA---VSEDAGGNE-GRAAEAEPRALENGDADEPS 152
               +  A A   V EDA   E    A+ EP   ++  A EPS
Sbjct: 903 VPTPEKEAPAKVEVKEDAKPKEKTEVAKKEP---DDAKAKEPS 942



 Score = 36.2 bits (82), Expect = 0.13
 Identities = 43/135 (31%), Positives = 55/135 (40%), Gaps = 19/135 (14%)

Query: 4   AENVAVPEA-AEERAEPGQQQPA-AEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEA- 60
           AE  A PE  A+   +   + PA A+ P  E    PA   +PE A + A  E     EA 
Sbjct: 506 AEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAK 565

Query: 61  GPESEVRTEPAA----------EAEAASGPSESPSPPAAE----ELPGSHAEPPVPAQGE 106
            PE E    PA             E A  P+E+ SP  A+    E   S AE   P + E
Sbjct: 566 SPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEE 625

Query: 107 A--PGEQARDERSDS 119
           A  P E    E++ S
Sbjct: 626 AKSPAEVKSPEKAKS 640



 Score = 34.7 bits (78), Expect = 0.37
 Identities = 32/166 (19%), Positives = 59/166 (35%), Gaps = 11/166 (6%)

Query: 8    AVPEAAEERAEPGQQQPAAEPP-PAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEV 66
            A P+  E++    ++ P  E P P     +      P+ +  EA  EE    +  P  E 
Sbjct: 849  ATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEK 908

Query: 67   RTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARD----------ER 116
                  E +  + P E       E       EP  PA+ +    + +D          E+
Sbjct: 909  EAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEK 968

Query: 117  SDSRAQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFVDD 162
              + A+A  +D   ++  +     +A ++   D+     PE   +D
Sbjct: 969  PKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATED 1014


>gi|118601081 heterogeneous nuclear ribonucleoprotein U-like 2 [Homo
           sapiens]
          Length = 747

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 38/126 (30%), Positives = 54/126 (42%), Gaps = 10/126 (7%)

Query: 11  EAAEERAEPGQQQPAAEPPPAEGLLRPA--GPGAPEAAGTEASSEEVGIAEAGPESEVRT 68
           E  EE  E   +    EPPPA+ L + A   P  PEAA  EA++E          SE   
Sbjct: 80  EEEEEDEEALLEDEDEEPPPAQALGQAAQPPPEPPEAAAMEAAAEP-------DASEKPA 132

Query: 69  EPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDA 128
           E  A +   +G  E       E+ P   +    P   E PG++A +E+ D +    S+ A
Sbjct: 133 EATAGSGGVNGGEEQGLGKREEDEPEERSGDETPG-SEVPGDKAAEEQGDDQDSEKSKPA 191

Query: 129 GGNEGR 134
           G +  R
Sbjct: 192 GSDGER 197



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 43/162 (26%), Positives = 59/162 (36%), Gaps = 31/162 (19%)

Query: 44  EAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASGPS--------------------ES 83
           EA   E   +E G   AGP    + EP   A +  GP                     E 
Sbjct: 35  EALDAEMLEDEAGGGGAGPGGACKAEPRPVAASGGGPGGDEEEDEEEEEEDEEALLEDED 94

Query: 84  PSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRAL 143
             PP A+ L  +   PP P +  A    A  + S+  A+A +   G N G     E + L
Sbjct: 95  EEPPPAQALGQAAQPPPEPPEAAAMEAAAEPDASEKPAEATAGSGGVNGG-----EEQGL 149

Query: 144 ENGDADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEADGIDS 185
              + DEP     E   D+    E+ GD  K   ++ D  DS
Sbjct: 150 GKREEDEPE----ERSGDETPGSEVPGD--KAAEEQGDDQDS 185



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 38/135 (28%), Positives = 51/135 (37%), Gaps = 10/135 (7%)

Query: 2   QDAENVAVPEAAEERAEPGQ-----QQPAAEPPPAEGLLRPAGPGAPE--AAGTEASSEE 54
           ++ +  A+ E  +E   P Q      QP  EPP A  +   A P A E  A  T  S   
Sbjct: 82  EEEDEEALLEDEDEEPPPAQALGQAAQPPPEPPEAAAMEAAAEPDASEKPAEATAGSGGV 141

Query: 55  VGIAEAGPESEVRTEPAAEAEAASGPSESPSPPAAEEL---PGSHAEPPVPAQGEAPGEQ 111
            G  E G       EP   +   +  SE P   AAEE      S    P  + GE  G +
Sbjct: 142 NGGEEQGLGKREEDEPEERSGDETPGSEVPGDKAAEEQGDDQDSEKSKPAGSDGERRGVK 201

Query: 112 ARDERSDSRAQAVSE 126
            + +  D   +A  E
Sbjct: 202 RQRDEKDEHGRAYYE 216



 Score = 33.9 bits (76), Expect = 0.62
 Identities = 35/137 (25%), Positives = 46/137 (33%), Gaps = 33/137 (24%)

Query: 10  PEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAG---PESEV 66
           PE  E  A     +P A   PAE      G    E  G     E+     +G   P SEV
Sbjct: 111 PEPPEAAAMEAAAEPDASEKPAEATAGSGGVNGGEEQGLGKREEDEPEERSGDETPGSEV 170

Query: 67  RTEPAAEAEAASGPSESPSPPAA-------------------------EELPGSHAEPPV 101
             + AAE +     SE   P  +                         EE   S ++ P+
Sbjct: 171 PGDKAAEEQGDDQDSEKSKPAGSDGERRGVKRQRDEKDEHGRAYYEFREEAYHSRSKSPL 230

Query: 102 PAQGEAPGEQARDERSD 118
           P     P E+A+DE  D
Sbjct: 231 P-----PEEEAKDEEED 242


>gi|226053185 paternally expressed 3 isoform 3 [Homo sapiens]
          Length = 1464

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 44/127 (34%), Positives = 56/127 (44%), Gaps = 16/127 (12%)

Query: 44   EAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPA 103
            +    EA+  EV  AE  PE E   EP  EA   +G +E P   AAE + G   +P    
Sbjct: 1264 QGLNVEAAEPEVEAAE--PEVEA-AEPEVEAAEPNGEAEGPDGEAAEPI-GEAGQP--NG 1317

Query: 104  QGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDADEP---SFSDPEDFV 160
            + E P   A DE   +  +   E A   EG+A E E      GDADEP      DPE+  
Sbjct: 1318 EAEQPNGDA-DEPDGAGIEDPEERAEEPEGKAEEPE------GDADEPDGVGIEDPEEGE 1370

Query: 161  DDVSEEE 167
            D   + E
Sbjct: 1371 DQEIQVE 1377



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 37/131 (28%), Positives = 53/131 (40%), Gaps = 11/131 (8%)

Query: 63   ESEVRTEPAAEAEAASGPSESPS--PPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSR 120
            E E   E AA A AA+   E+    P     + G + E   P + EA   +      +  
Sbjct: 1232 EEEEEDEAAAAAAAAAQEVEANVHVPQVVLRIQGLNVEAAEP-EVEAAEPEVEAAEPEVE 1290

Query: 121  AQAVSEDAGGNEGRAAEAEPRALE--------NGDADEPSFSDPEDFVDDVSEEELLGDV 172
            A   + +A G +G AAE    A +        NGDADEP  +  ED  +   E E   + 
Sbjct: 1291 AAEPNGEAEGPDGEAAEPIGEAGQPNGEAEQPNGDADEPDGAGIEDPEERAEEPEGKAEE 1350

Query: 173  LKDRPQEADGI 183
             +    E DG+
Sbjct: 1351 PEGDADEPDGV 1361


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.133    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,886,810
Number of Sequences: 37866
Number of extensions: 1796742
Number of successful extensions: 18165
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 201
Number of HSP's successfully gapped in prelim test: 1263
Number of HSP's that attempted gapping in prelim test: 12378
Number of HSP's gapped (non-prelim): 5549
length of query: 814
length of database: 18,247,518
effective HSP length: 111
effective length of query: 703
effective length of database: 14,044,392
effective search space: 9873207576
effective search space used: 9873207576
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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