BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|33239445 eukaryotic translation initiation factor 3, subunit 9 eta, 116kDa [Homo sapiens] (814 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|33239445 eukaryotic translation initiation factor 3, subunit ... 1671 0.0 gi|83367072 eukaryotic translation initiation factor 3, subunit ... 1671 0.0 gi|54873624 eukaryotic translation initiation factor 2A [Homo sa... 89 2e-17 gi|27894378 chloride intracellular channel 6 [Homo sapiens] 59 2e-08 gi|30795231 brain abundant, membrane attached signal protein 1 [... 56 1e-07 gi|33286446 opioid growth factor receptor [Homo sapiens] 53 1e-06 gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 53 1e-06 gi|110832843 TBP-associated factor 4 [Homo sapiens] 52 2e-06 gi|23503317 coiled-coil domain containing 96 [Homo sapiens] 50 6e-06 gi|193083172 nuclear assembly factor 1 homolog isoform b [Homo s... 50 8e-06 gi|193083157 nuclear assembly factor 1 homolog isoform a [Homo s... 50 8e-06 gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 49 1e-05 gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 48 3e-05 gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] 48 3e-05 gi|117938759 GNAS complex locus XLas [Homo sapiens] 48 4e-05 gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 48 4e-05 gi|153070260 myristoylated alanine-rich protein kinase C substra... 47 5e-05 gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Hom... 47 9e-05 gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Hom... 47 9e-05 gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo ... 47 9e-05 gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 47 9e-05 gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 47 9e-05 gi|117938310 sine oculis binding protein homolog [Homo sapiens] 47 9e-05 gi|140972063 protein phosphatase 1, regulatory subunit 9B [Homo ... 46 1e-04 gi|163965366 nascent polypeptide-associated complex alpha subuni... 46 1e-04 gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 46 2e-04 gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 46 2e-04 gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 46 2e-04 gi|118601081 heterogeneous nuclear ribonucleoprotein U-like 2 [H... 46 2e-04 gi|226053185 paternally expressed 3 isoform 3 [Homo sapiens] 45 2e-04 >gi|33239445 eukaryotic translation initiation factor 3, subunit 9 eta, 116kDa [Homo sapiens] Length = 814 Score = 1671 bits (4327), Expect = 0.0 Identities = 814/814 (100%), Positives = 814/814 (100%) Query: 1 MQDAENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEA 60 MQDAENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEA Sbjct: 1 MQDAENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEA 60 Query: 61 GPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSR 120 GPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSR Sbjct: 61 GPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSR 120 Query: 121 AQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEA 180 AQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEA Sbjct: 121 AQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEA 180 Query: 181 DGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKITNDFYPEEDGKTKGYIFLEYASP 240 DGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKITNDFYPEEDGKTKGYIFLEYASP Sbjct: 181 DGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKITNDFYPEEDGKTKGYIFLEYASP 240 Query: 241 AHAVDAVKNADGYKLDKQHTFRVNLFTDFDKYMTISDEWDIPEKQPFKDLGNLRYWLEEA 300 AHAVDAVKNADGYKLDKQHTFRVNLFTDFDKYMTISDEWDIPEKQPFKDLGNLRYWLEEA Sbjct: 241 AHAVDAVKNADGYKLDKQHTFRVNLFTDFDKYMTISDEWDIPEKQPFKDLGNLRYWLEEA 300 Query: 301 ECRDQYSVIFESGDRTSIFWNDVKDPVSIEERARWTETYVRWSPKGTYLATFHQRGIALW 360 ECRDQYSVIFESGDRTSIFWNDVKDPVSIEERARWTETYVRWSPKGTYLATFHQRGIALW Sbjct: 301 ECRDQYSVIFESGDRTSIFWNDVKDPVSIEERARWTETYVRWSPKGTYLATFHQRGIALW 360 Query: 361 GGEKFKQIQRFSHQGVQLIDFSPCERYLVTFSPLMDTQDDPQAIIIWDILTGHKKRGFHC 420 GGEKFKQIQRFSHQGVQLIDFSPCERYLVTFSPLMDTQDDPQAIIIWDILTGHKKRGFHC Sbjct: 361 GGEKFKQIQRFSHQGVQLIDFSPCERYLVTFSPLMDTQDDPQAIIIWDILTGHKKRGFHC 420 Query: 421 ESSAHWPIFKWSHDGKFFARMTLDTLSIYETPSMGLLDKKSLKISGIKDFSWSPGGNIIA 480 ESSAHWPIFKWSHDGKFFARMTLDTLSIYETPSMGLLDKKSLKISGIKDFSWSPGGNIIA Sbjct: 421 ESSAHWPIFKWSHDGKFFARMTLDTLSIYETPSMGLLDKKSLKISGIKDFSWSPGGNIIA 480 Query: 481 FWVPEDKDIPARVTLMQLPTRQEIRVRNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQGV 540 FWVPEDKDIPARVTLMQLPTRQEIRVRNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQGV Sbjct: 481 FWVPEDKDIPARVTLMQLPTRQEIRVRNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQGV 540 Query: 541 VTNFEIFRMREKQVPVDVVEMKETIIAFAWEPNGSKFAVLHGEAPRISVSFYHVKNNGKI 600 VTNFEIFRMREKQVPVDVVEMKETIIAFAWEPNGSKFAVLHGEAPRISVSFYHVKNNGKI Sbjct: 541 VTNFEIFRMREKQVPVDVVEMKETIIAFAWEPNGSKFAVLHGEAPRISVSFYHVKNNGKI 600 Query: 601 ELIKMFDKQQANTIFWSPQGQFVVLAGLRSMNGALAFVDTSDCTVMNIAEHYMASDVEWD 660 ELIKMFDKQQANTIFWSPQGQFVVLAGLRSMNGALAFVDTSDCTVMNIAEHYMASDVEWD Sbjct: 601 ELIKMFDKQQANTIFWSPQGQFVVLAGLRSMNGALAFVDTSDCTVMNIAEHYMASDVEWD 660 Query: 661 PTGRYVVTSVSWWSHKVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQEQIKQI 720 PTGRYVVTSVSWWSHKVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQEQIKQI Sbjct: 661 PTGRYVVTSVSWWSHKVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQEQIKQI 720 Query: 721 KKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRKYRKMAQELYMEQKNERLELRG 780 KKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRKYRKMAQELYMEQKNERLELRG Sbjct: 721 KKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRKYRKMAQELYMEQKNERLELRG 780 Query: 781 GVDTDELDSNVDDWEEETIEFFVTEEIIPLGNQE 814 GVDTDELDSNVDDWEEETIEFFVTEEIIPLGNQE Sbjct: 781 GVDTDELDSNVDDWEEETIEFFVTEEIIPLGNQE 814 >gi|83367072 eukaryotic translation initiation factor 3, subunit 9 eta, 116kDa [Homo sapiens] Length = 814 Score = 1671 bits (4327), Expect = 0.0 Identities = 814/814 (100%), Positives = 814/814 (100%) Query: 1 MQDAENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEA 60 MQDAENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEA Sbjct: 1 MQDAENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEA 60 Query: 61 GPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSR 120 GPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSR Sbjct: 61 GPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSR 120 Query: 121 AQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEA 180 AQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEA Sbjct: 121 AQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEA 180 Query: 181 DGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKITNDFYPEEDGKTKGYIFLEYASP 240 DGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKITNDFYPEEDGKTKGYIFLEYASP Sbjct: 181 DGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKITNDFYPEEDGKTKGYIFLEYASP 240 Query: 241 AHAVDAVKNADGYKLDKQHTFRVNLFTDFDKYMTISDEWDIPEKQPFKDLGNLRYWLEEA 300 AHAVDAVKNADGYKLDKQHTFRVNLFTDFDKYMTISDEWDIPEKQPFKDLGNLRYWLEEA Sbjct: 241 AHAVDAVKNADGYKLDKQHTFRVNLFTDFDKYMTISDEWDIPEKQPFKDLGNLRYWLEEA 300 Query: 301 ECRDQYSVIFESGDRTSIFWNDVKDPVSIEERARWTETYVRWSPKGTYLATFHQRGIALW 360 ECRDQYSVIFESGDRTSIFWNDVKDPVSIEERARWTETYVRWSPKGTYLATFHQRGIALW Sbjct: 301 ECRDQYSVIFESGDRTSIFWNDVKDPVSIEERARWTETYVRWSPKGTYLATFHQRGIALW 360 Query: 361 GGEKFKQIQRFSHQGVQLIDFSPCERYLVTFSPLMDTQDDPQAIIIWDILTGHKKRGFHC 420 GGEKFKQIQRFSHQGVQLIDFSPCERYLVTFSPLMDTQDDPQAIIIWDILTGHKKRGFHC Sbjct: 361 GGEKFKQIQRFSHQGVQLIDFSPCERYLVTFSPLMDTQDDPQAIIIWDILTGHKKRGFHC 420 Query: 421 ESSAHWPIFKWSHDGKFFARMTLDTLSIYETPSMGLLDKKSLKISGIKDFSWSPGGNIIA 480 ESSAHWPIFKWSHDGKFFARMTLDTLSIYETPSMGLLDKKSLKISGIKDFSWSPGGNIIA Sbjct: 421 ESSAHWPIFKWSHDGKFFARMTLDTLSIYETPSMGLLDKKSLKISGIKDFSWSPGGNIIA 480 Query: 481 FWVPEDKDIPARVTLMQLPTRQEIRVRNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQGV 540 FWVPEDKDIPARVTLMQLPTRQEIRVRNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQGV Sbjct: 481 FWVPEDKDIPARVTLMQLPTRQEIRVRNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQGV 540 Query: 541 VTNFEIFRMREKQVPVDVVEMKETIIAFAWEPNGSKFAVLHGEAPRISVSFYHVKNNGKI 600 VTNFEIFRMREKQVPVDVVEMKETIIAFAWEPNGSKFAVLHGEAPRISVSFYHVKNNGKI Sbjct: 541 VTNFEIFRMREKQVPVDVVEMKETIIAFAWEPNGSKFAVLHGEAPRISVSFYHVKNNGKI 600 Query: 601 ELIKMFDKQQANTIFWSPQGQFVVLAGLRSMNGALAFVDTSDCTVMNIAEHYMASDVEWD 660 ELIKMFDKQQANTIFWSPQGQFVVLAGLRSMNGALAFVDTSDCTVMNIAEHYMASDVEWD Sbjct: 601 ELIKMFDKQQANTIFWSPQGQFVVLAGLRSMNGALAFVDTSDCTVMNIAEHYMASDVEWD 660 Query: 661 PTGRYVVTSVSWWSHKVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQEQIKQI 720 PTGRYVVTSVSWWSHKVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQEQIKQI Sbjct: 661 PTGRYVVTSVSWWSHKVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQEQIKQI 720 Query: 721 KKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRKYRKMAQELYMEQKNERLELRG 780 KKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRKYRKMAQELYMEQKNERLELRG Sbjct: 721 KKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRKYRKMAQELYMEQKNERLELRG 780 Query: 781 GVDTDELDSNVDDWEEETIEFFVTEEIIPLGNQE 814 GVDTDELDSNVDDWEEETIEFFVTEEIIPLGNQE Sbjct: 781 GVDTDELDSNVDDWEEETIEFFVTEEIIPLGNQE 814 >gi|54873624 eukaryotic translation initiation factor 2A [Homo sapiens] Length = 585 Score = 88.6 bits (218), Expect = 2e-17 Identities = 91/396 (22%), Positives = 161/396 (40%), Gaps = 39/396 (9%) Query: 339 YVRWSPKGTYLATFHQRG-IALWGGEKFKQIQRFSHQGVQ---------LIDFSPCERYL 388 + R S K + F + G + WG + I +++G+ ++FSP L Sbjct: 31 FPRESGKNCKVCIFSKDGTLFAWGNGEKVNIISVTNKGLLHSFDLLKAVCLEFSPKNTVL 90 Query: 389 VTFSPLMDTQDDPQAII---IWDILTGHKKRGFHCESSAHWPIFKWSHDGKFFARMTLDT 445 T+ P ++D I ++D+ TG + F + +W WS D AR + Sbjct: 91 ATWQPYTTSKDGTAGIPNLQLYDVKTGTCLKSFIQKKMQNW-CPSWSEDETLCARNVNNE 149 Query: 446 LSIYETPSMGLLDKKSLKISGIKDFSWSPGGNI--IAFWVPEDKDIPARVTLMQLPT--- 500 + +E + + K L + I DF SPG +A +VP K P+ V L Q P Sbjct: 150 VHFFENNNFNTIANK-LHLQKINDFVLSPGPQPYKVAVYVPGSKGAPSFVRLYQYPNFAG 208 Query: 501 -RQEIRVRNLFNVVDCKLHWQKNGDYLCV----KVDRTPKGTQGVVTNFEIFRMREKQVP 555 + ++ F + W K + V VD+T G T I E V Sbjct: 209 PHAALANKSFFKADKVTMLWNKKATAVLVIASTDVDKTGASYYGEQTLHYIATNGESAV- 267 Query: 556 VDVVEMKET--IIAFAWEPNGSKFAVLHGEAPRISVSFYHVKNNGKIELIKMFDKQQANT 613 V++ + I W + ++F ++G P + F N K + + F N Sbjct: 268 ---VQLPKNGPIYDVVWNSSSTEFCAVYGFMPAKATIF-----NLKCDPVFDFGTGPRNA 319 Query: 614 IFWSPQGQFVVLAGLRSMNGALAFVDTSDCTVMNIAEHYMASDVEWDPTGRYVVTSVSWW 673 ++SP G +VLAG ++ G + D + +++ ++ W P G +++T+ Sbjct: 320 AYYSPHGHILVLAGFGNLRGQMEVWDVKNYKLISKPVASDSTYFAWCPDGEHILTATCAP 379 Query: 674 SHKVDNAYWLWTFQGRLLQK---NNKDRFCQLLWRP 706 +V+N Y +W + G +L K + Q+ W+P Sbjct: 380 RLRVNNGYKIWHYTGSILHKYDVPSNAELWQVSWQP 415 >gi|27894378 chloride intracellular channel 6 [Homo sapiens] Length = 686 Score = 58.5 bits (140), Expect = 2e-08 Identities = 71/223 (31%), Positives = 92/223 (41%), Gaps = 46/223 (20%) Query: 11 EAAE-ERAEPGQQQPAAEPPP-AEGLLRPAGPGAP--EAAGTEAS--SEEV--------- 55 EAAE E PG Q P P P AE RP PGA EA G E S +EE Sbjct: 3 EAAEPEGVAPGPQGPPEVPAPLAE---RPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKE 59 Query: 56 ---GIAEAGPESEVRTEPAA--EAEAASG-PSESPSPPAAEELPGSH----AEPPVPAQG 105 G + GPE+E R A E EA G P + P EE G+ A P AQG Sbjct: 60 AGGGGPDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQG 119 Query: 106 EAPGEQARD----------ERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSD 155 E GE R+ E ++ R + A G G + +AE +N +A+ P+ Sbjct: 120 EPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPA--- 176 Query: 156 PEDFVDDVSEEELLGDVLKDRPQEADGIDSV-IVVDNVPQVGP 197 D V E +GD + D +D+ + DN+ GP Sbjct: 177 ----GDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGP 215 Score = 39.3 bits (90), Expect = 0.015 Identities = 53/199 (26%), Positives = 74/199 (37%), Gaps = 20/199 (10%) Query: 5 ENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPES 64 E VP+ EE + Q + A+ A+G R PE + A PE Sbjct: 91 EGAEVPQGGEETSGAQQVEGASPGRGAQGEPRGEAQREPEDS-------------AAPER 137 Query: 65 EVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQA- 123 + E E S E+ AE G + E PA E + D+ A Sbjct: 138 QEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPAGDSVEAEGRVGDSVDAEGPAG 197 Query: 124 VSEDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFV----DDVSEEELLGDVLKDRPQE 179 S DA G G +AE A ++ DA E D D D V E +GD ++ Sbjct: 198 DSVDAEGPLGDNIQAEGPAGDSVDA-EGRVGDSVDAEGPAGDSVDAEGRVGDSVEAGDPA 256 Query: 180 ADGIDS-VIVVDNVPQVGP 197 DG+++ V D+V GP Sbjct: 257 GDGVEAGVPAGDSVEAEGP 275 Score = 38.9 bits (89), Expect = 0.019 Identities = 28/73 (38%), Positives = 33/73 (45%), Gaps = 5/73 (6%) Query: 74 AEAASGPSESPSPPAAEELPGSHAE---PPVPAQGEAPGEQARD--ERSDSRAQAVSEDA 128 AEAA +P P E+P AE P A GEA G + + E + A AV E Sbjct: 2 AEAAEPEGVAPGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAG 61 Query: 129 GGNEGRAAEAEPR 141 GG R EAE R Sbjct: 62 GGGPDRGPEAEAR 74 Score = 37.4 bits (85), Expect = 0.056 Identities = 43/149 (28%), Positives = 57/149 (38%), Gaps = 13/149 (8%) Query: 4 AENVAVPEAAEERAEPGQQQ-PAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGP 62 AE + V PG+ AAE G+ + + AP A +A + VG GP Sbjct: 308 AEAIEVAAGESAGRSPGELAWDAAEEAEVPGV-KGSEEAAPGDARADAGEDRVG---DGP 363 Query: 63 ESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQ 122 + E + + GP E + EE P S GEA A E S Sbjct: 364 QQEPGEDEERRERSPEGPREEEAAGGEEESPDS------SPHGEASRGAAEPEAQLSNHL 417 Query: 123 AVSEDAGGNEGRAAEAEPRALENGDADEP 151 A A G+ G AA R E+G+A EP Sbjct: 418 AEEGPAEGS-GEAARVNGRR-EDGEASEP 444 Score = 33.5 bits (75), Expect = 0.81 Identities = 52/176 (29%), Positives = 68/176 (38%), Gaps = 31/176 (17%) Query: 24 PAAEPPPAEGLLR-------PAGPGAPEAAGTEASSEEVGI-AEAGPESEVRTEPAAEAE 75 PA + AEG + PAG +A G S E G A G E+ V + EAE Sbjct: 215 PAGDSVDAEGRVGDSVDAEGPAGDSV-DAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAE 273 Query: 76 AASGPSESPSPPA--AEELPGS-----------HAEPPVPAQGE----APGEQARDERSD 118 +G S PA A + G AE A GE +PGE A D + Sbjct: 274 GPAGDSMDAEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPGELAWDAAEE 333 Query: 119 SRAQAV--SEDAGGNEGRAAEAEPRALENGDADEPSFSDP--EDFVDDVSEEELLG 170 + V SE+A + RA E R + +G EP + E + EEE G Sbjct: 334 AEVPGVKGSEEAAPGDARADAGEDR-VGDGPQQEPGEDEERRERSPEGPREEEAAG 388 >gi|30795231 brain abundant, membrane attached signal protein 1 [Homo sapiens] Length = 227 Score = 56.2 bits (134), Expect = 1e-07 Identities = 51/189 (26%), Positives = 80/189 (42%), Gaps = 23/189 (12%) Query: 2 QDAENVAVPEAAEERAEPGQQQPAAEPPPAE---GLLRPAGPGAPEAAGTEASSEEVGIA 58 ++ + A A EE P + +P A PAE G +P +A E + Sbjct: 20 KEKDKKAEGAATEEEGTPKESEPQAAAEPAEAKEGKEKPDQDAEGKAEEKEGEKDAAAAK 79 Query: 59 EAGPESEV-RTEPAAEA-----------EAASGPSESPSPPAAEELPGSHAEPPVPAQGE 106 E P++E +TE AAEA +AA GP+ P A E + AE PA GE Sbjct: 80 EEAPKAEPEKTEGAAEAKAEPPKAPEQEQAAPGPAAGGEAPKAAEAAAAPAESAAPAAGE 139 Query: 107 APG-EQARDERSDSRAQAVSED-------AGGNEGRAAEAEPRALENGDADEPSFSDPED 158 P E+ +++++ A +++ A ++ ++EA P + E A E S P+ Sbjct: 140 EPSKEEGEPKKTEAPAAPAAQETKSDGAPASDSKPGSSEAAPSSKETPAATEAPSSTPKA 199 Query: 159 FVDDVSEEE 167 S EE Sbjct: 200 QGPAASAEE 208 Score = 41.6 bits (96), Expect = 0.003 Identities = 38/107 (35%), Positives = 49/107 (45%), Gaps = 19/107 (17%) Query: 10 PEAAEERAEPGQQQ-PAA--EPPPAEGLLR----PAGPGAPEAA--GTEASSEEVGIAEA 60 P+AAE A P + PAA EP EG + PA P A E G AS + G +EA Sbjct: 120 PKAAEAAAAPAESAAPAAGEEPSKEEGEPKKTEAPAAPAAQETKSDGAPASDSKPGSSEA 179 Query: 61 GPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEA 107 P S + PAA +E+PS + P + AE P P + A Sbjct: 180 APSS--KETPAA--------TEAPSSTPKAQGPAASAEEPKPVEAPA 216 Score = 40.0 bits (92), Expect = 0.009 Identities = 32/99 (32%), Positives = 45/99 (45%), Gaps = 13/99 (13%) Query: 8 AVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPE--AAGTEASSEEVGIAEAGP--- 62 A P A E EP +++ EP E PA P A E + G AS + G +EA P Sbjct: 133 AAPAAGE---EPSKEE--GEPKKTEA---PAAPAAQETKSDGAPASDSKPGSSEAAPSSK 184 Query: 63 ESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPV 101 E+ TE + A GP+ S P E P ++++ V Sbjct: 185 ETPAATEAPSSTPKAQGPAASAEEPKPVEAPAANSDQTV 223 Score = 32.0 bits (71), Expect = 2.4 Identities = 37/134 (27%), Positives = 53/134 (39%), Gaps = 24/134 (17%) Query: 44 EAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASGPSESPSPPA---AEELPGSHAEPP 100 +A + +E E G E + AAE A E P A AEE G + Sbjct: 18 KAKEKDKKAEGAATEEEGTPKESEPQAAAEPAEAKEGKEKPDQDAEGKAEEKEGE--KDA 75 Query: 101 VPAQGEAPGEQARDERSDSRAQAVSED--------------AGGNEGRAAEAEPRALEN- 145 A+ EAP +A E+++ A+A +E AGG +AAEA E+ Sbjct: 76 AAAKEEAP--KAEPEKTEGAAEAKAEPPKAPEQEQAAPGPAAGGEAPKAAEAAAAPAESA 133 Query: 146 --GDADEPSFSDPE 157 +EPS + E Sbjct: 134 APAAGEEPSKEEGE 147 >gi|33286446 opioid growth factor receptor [Homo sapiens] Length = 677 Score = 53.1 bits (126), Expect = 1e-06 Identities = 45/147 (30%), Positives = 58/147 (39%), Gaps = 21/147 (14%) Query: 17 AEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEA-- 74 A P +PA P G RPAGP E A E+ SE G AGP + E +E Sbjct: 527 AGPAGDEPAESPSETPGP-RPAGPAGDEPA--ESPSETPGPRPAGPAGDEPAESPSETPG 583 Query: 75 ---------EAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQ--- 122 E A PSE+P P A AE P G P A DE ++S ++ Sbjct: 584 PSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG 643 Query: 123 ----AVSEDAGGNEGRAAEAEPRALEN 145 + D G AAE + +E+ Sbjct: 644 PSPAGPTRDEPAKAGEAAELQDAEVES 670 Score = 49.3 bits (116), Expect = 1e-05 Identities = 47/175 (26%), Positives = 64/175 (36%), Gaps = 20/175 (11%) Query: 9 VPEAAEERAEPGQQQPAAE---PPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESE 65 V E E R P + P + P P+ PAGP E A E+ SE G AGP + Sbjct: 500 VEEDTEGRTGPKEGTPGSPSETPGPS-----PAGPAGDEPA--ESPSETPGPRPAGPAGD 552 Query: 66 VRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVS 125 E A PSE+P P A AE P G +P RDE ++S ++ Sbjct: 553 ---------EPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPG 603 Query: 126 EDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEA 180 G G P P+ +P + + G +D P +A Sbjct: 604 PRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPT-RDEPAKA 657 Score = 40.8 bits (94), Expect = 0.005 Identities = 36/105 (34%), Positives = 46/105 (43%), Gaps = 17/105 (16%) Query: 17 AEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEA 76 A P + +PA P G RPAGP E A E+ SE G AGP + E Sbjct: 587 AGPTRDEPAESPSETPGP-RPAGPAGDEPA--ESPSETPGPRPAGPAGD---------EP 634 Query: 77 ASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRA 121 A PSE+P P A G + P A GEA Q + S +++ Sbjct: 635 AESPSETPGPSPA----GPTRDEPAKA-GEAAELQDAEVESSAKS 674 Score = 39.7 bits (91), Expect = 0.011 Identities = 32/122 (26%), Positives = 47/122 (38%), Gaps = 7/122 (5%) Query: 37 PAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSH 96 PA G P+A +E EE GP+ P+ P SP+ PA +E S Sbjct: 485 PAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSET------PGPSPAGPAGDEPAESP 538 Query: 97 AEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDA-DEPSFSD 155 +E P P G++ + S++ + AG + P G DEP+ S Sbjct: 539 SETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESP 598 Query: 156 PE 157 E Sbjct: 599 SE 600 >gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] Length = 2400 Score = 52.8 bits (125), Expect = 1e-06 Identities = 64/219 (29%), Positives = 91/219 (41%), Gaps = 44/219 (20%) Query: 3 DAENVAVPEAAEERAEP-GQQQPAAEP---PPAEGLLRPAGPGA----------PEAAGT 48 ++E V PEA + E G+ QP +E P AEG +P PE+ G Sbjct: 1847 ESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGA 1906 Query: 49 EASSEEVGIAEAGPESE----VRTE----------PAAEAEAASGPSESPSPPAAEELPG 94 EA E EA PE+E + TE A EAE A+ +E + P +E + Sbjct: 1907 EAPEAE---KEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIES 1963 Query: 95 SHAE---PPVPAQGEAPGEQARDERSDSRAQAVSED--AGGNEGRAAEAEPRALENGDAD 149 AE P EA + + ++ AQ SED A EG EAE A D Sbjct: 1964 QEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGV 2023 Query: 150 EPSFSDPEDFVDDVSEEELLGDVLK---DRPQEADGIDS 185 E + P+ ++ E E G+ K D E+DG+++ Sbjct: 2024 E---AQPKSEGEEAQEVE--GETQKTEGDAQPESDGVEA 2057 Score = 52.4 bits (124), Expect = 2e-06 Identities = 54/189 (28%), Positives = 82/189 (43%), Gaps = 27/189 (14%) Query: 3 DAENVAVPEAAEERAEP--------GQQQPAAEP---PPAEGLLRPAGPG--APEAAGTE 49 +++ V PEA EE E G+ P +E AEG +P G APEA G Sbjct: 2051 ESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEA 2110 Query: 50 ASSEEVGI----AEAGPESEVRTEPAAEAEA-------ASGPSESPSPPAAEELPGSHAE 98 +E + EA PESE P AE EA + +E + P +E + AE Sbjct: 2111 QKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAE 2170 Query: 99 PPVPAQGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPED 158 AQ E G +A + +++ ++ +A EG A+ E +E +A+E + +PE Sbjct: 2171 E--EAQPELEGVEAPEAEGEAQPESEGIEAPEAEGE-AQPELEGVEAPEAEEEAQPEPEG 2227 Query: 159 FVDDVSEEE 167 +E E Sbjct: 2228 VETPEAEGE 2236 Score = 49.3 bits (116), Expect = 1e-05 Identities = 51/159 (32%), Positives = 63/159 (39%), Gaps = 30/159 (18%) Query: 2 QDAENVAVPEA-------AEERAEPGQQQPAAEPPPAEGLLRPAGPG--APEAAGTEASS 52 QDAE A PE+ AEE A+P + E P AEG +P G APEA G Sbjct: 2151 QDAEGEAQPESEGIEAQEAEEEAQP--ELEGVEAPEAEGEAQPESEGIEAPEAEG----- 2203 Query: 53 EEVGIAEAGPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQA 112 EA PE E P AE EA P P E P + E ++GE GE+ Sbjct: 2204 ------EAQPELEGVEAPEAEEEA------QPEPEGV-ETPEAEGEAQPESEGETQGEK- 2249 Query: 113 RDERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDADEP 151 + S SE+A + E P + D P Sbjct: 2250 KGSPQVSLGDGQSEEASESSSPVPEDRPTPPPSPGGDTP 2288 Score = 48.5 bits (114), Expect = 2e-05 Identities = 52/179 (29%), Positives = 64/179 (35%), Gaps = 32/179 (17%) Query: 1 MQDAENVAVPEAAEERAEP------------------GQQQPAA----------EPPPAE 32 MQ+AE A PE+ A+P G QP + E AE Sbjct: 2009 MQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAE 2068 Query: 33 GLLRPA-GPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASGPSESPSPPAAEE 91 G ++ A G PE+ +A E EA PESE P AE EA E Sbjct: 2069 GEVQEAEGEAHPESEDVDAQEAE---GEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEA 2125 Query: 92 LPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDADE 150 P S A+GEA E E D+ +A E G A E LE +A E Sbjct: 2126 QPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPE 2184 Score = 47.0 bits (110), Expect = 7e-05 Identities = 52/202 (25%), Positives = 86/202 (42%), Gaps = 27/202 (13%) Query: 3 DAENVAVPE--AAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAG-TEASSEEVGIAE 59 +AE A PE + E G+ +P +E A+ A A EA G T+ SE + E Sbjct: 1910 EAEKEAQPETESVEALETEGEDEPESEGAEAQ----EAEEAAQEAEGQTQPESEVIESQE 1965 Query: 60 AGPESEVRTE--PAAEAEAASGPSESPSPPAAEELPGSHAEPPV-----PAQGEAPGEQA 112 A E++ +E A E E + +E + P +E++ AE + AQ E+ G +A Sbjct: 1966 AEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEA 2025 Query: 113 RDERSDSRAQAVSEDAGGNEG---------RAAEAEPRALENGDADEPSFSDPEDFVDDV 163 + + AQ V + EG A EAE A E + + + +DV Sbjct: 2026 QPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDV 2085 Query: 164 SEEELLGDVLKDRPQEADGIDS 185 +E G+ E++G+++ Sbjct: 2086 DAQEAEGEA----QPESEGVEA 2103 Score = 46.2 bits (108), Expect = 1e-04 Identities = 59/224 (26%), Positives = 88/224 (39%), Gaps = 43/224 (19%) Query: 2 QDAENVAVPEA---------AEERAEPGQQQPAAEP---PPAEGLLRPAGPGA-PEAAGT 48 Q+AE A PE+ E + G+ QP +E P AEG ++ A A PE+ G Sbjct: 1964 QEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGV 2023 Query: 49 EASSEEVG-------------IAEAGPESEVRTEPAAEAEAASG-----PSESPSPPAAE 90 EA + G +A PES+ P AE EA +E + P +E Sbjct: 2024 EAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESE 2083 Query: 91 ELPGSHAEPPVPAQG------EAPGEQARDE-----RSDSRAQAVSEDAGGNEGRA-AEA 138 ++ AE + EA GE + E ++ AQ SE E A+ Sbjct: 2084 DVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQP 2143 Query: 139 EPRALENGDADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEADG 182 E +E DA+ + + E +EEE ++ EA+G Sbjct: 2144 ESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEG 2187 Score = 39.7 bits (91), Expect = 0.011 Identities = 49/157 (31%), Positives = 61/157 (38%), Gaps = 22/157 (14%) Query: 11 EAAEERAEPGQQQPAAEPPPAEGLLRPAG---PGAPEAA-GTEASSEEVGIAEAGPESEV 66 E ER E G Q E +G G PG + A G EA E EA PESE Sbjct: 1795 EGISERGETGGQGSGHEDN-LQGEAAAGGDQDPGQSDGAEGIEAPEAE---GEAQPESEG 1850 Query: 67 RTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSE 126 P AE +A +E + P +E++ AE GEA E E ++ + E Sbjct: 1851 VEAPEAEGDAQE--AEGEAQPESEDVEAPEAE------GEAQPESEDVETPEAEWEVQPE 1902 Query: 127 DAGGNEGRA-AEAEP-----RALENGDADEPSFSDPE 157 G A EA+P ALE DEP E Sbjct: 1903 SEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAE 1939 Score = 32.0 bits (71), Expect = 2.4 Identities = 37/153 (24%), Positives = 53/153 (34%), Gaps = 21/153 (13%) Query: 18 EPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGI-AEAGPESEVRTEPAAEAEA 76 + G +QP P P A + AG+ SEE + + GP+ + E A+ Sbjct: 889 QEGTRQPGPTPSPGPNSGASRRSSASQGAGSRGLSEEKTLRSGGGPQGQ---EEASGVSP 945 Query: 77 ASGPSESPSPPAAEELPGSHAEPPVPAQGEA-----------------PGEQARDERSDS 119 +S P SP E L EP + A PG+ E Sbjct: 946 SSLPRSSPEAVVREWLDNIPEEPILMTYELADETTGAAGGGLRGPEVDPGDDHSLEGLGE 1005 Query: 120 RAQAVSEDAGGNEGRAAEAEPRALENGDADEPS 152 AQA + G+ G+ E E L + D S Sbjct: 1006 PAQAGQQSLEGDPGQDPEPEGALLGSSDTGPQS 1038 Score = 30.4 bits (67), Expect = 6.9 Identities = 43/157 (27%), Positives = 60/157 (38%), Gaps = 27/157 (17%) Query: 23 QPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASGPSE 82 Q +A P + GL P G PE++ + E+ G+ A P +++ AE +A E Sbjct: 450 QDSASPASSTGL--PEG-SEPESSCCPRTPED-GVDSASPSAQI----GAERKAGGSLGE 501 Query: 83 SPSPPAAEELPGSHAEPPVPAQGEAPGEQARDER---SDSRAQAVSEDAGGNEG------ 133 P L A P QG +AR E SDS A S + G Sbjct: 502 DPG------LCIDGAGLGGPEQGGRLTPRARSEEGASSDSSASTGSHEGSSEWGGRPQGC 555 Query: 134 ----RAAEAEPRALENGDADEPSFSDPEDFVDDVSEE 166 RA ++ A E GD P+ S DD+ E Sbjct: 556 PGKARAETSQQEASEGGDPASPALSLSSLRSDDLQAE 592 Score = 30.4 bits (67), Expect = 6.9 Identities = 21/80 (26%), Positives = 35/80 (43%), Gaps = 6/80 (7%) Query: 15 ERAEPGQQQPAAEPPPAEGLLRPAGPGA------PEAAGTEASSEEVGIAEAGPESEVRT 68 + E G+ +AEP PAEG P P + P A+ ++ S+ E P + + Sbjct: 1428 QEEEAGRASASAEPCPAEGTEEPTEPPSHLSETDPSASERQSGSQLEPGLEKPPGATMMG 1487 Query: 69 EPAAEAEAASGPSESPSPPA 88 + +A+ G +E S A Sbjct: 1488 QEHTQAQPTQGAAERSSSVA 1507 >gi|110832843 TBP-associated factor 4 [Homo sapiens] Length = 1085 Score = 52.4 bits (124), Expect = 2e-06 Identities = 55/192 (28%), Positives = 65/192 (33%), Gaps = 40/192 (20%) Query: 8 AVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGA------------------------- 42 A P A RA PG P P P G +PAGPGA Sbjct: 161 AGPAALAARAGPGPG-PGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVN 219 Query: 43 -----------PEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASGPSESPSPPAAEE 91 P A GT + A A P + PAA A AA + P PPA Sbjct: 220 NGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPAT 279 Query: 92 L---PGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDA 148 L PG A PP A P A++ S A A + AGG G + + P A A Sbjct: 280 LARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPA 339 Query: 149 DEPSFSDPEDFV 160 P+ V Sbjct: 340 PGVKAESPKRVV 351 Score = 42.0 bits (97), Expect = 0.002 Identities = 41/148 (27%), Positives = 52/148 (35%), Gaps = 16/148 (10%) Query: 17 AEPGQQQPAAEP-PPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPA---- 71 A P + P A P PP G RP G G V A P +++R P Sbjct: 76 AAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAG 135 Query: 72 ------AEAEAASGPSESPSPPAAEELPGSHAEP----PVPAQGEAPGEQARDERSDSRA 121 A A A+GP +P+ PA P + A P P G PG A Sbjct: 136 SCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAA 195 Query: 122 QAVSEDAG-GNEGRAAEAEPRALENGDA 148 Q ++ A N AA + NG A Sbjct: 196 QTLNGSAALLNSHHAAAPAVSLVNNGPA 223 Score = 41.6 bits (96), Expect = 0.003 Identities = 36/112 (32%), Positives = 46/112 (41%), Gaps = 12/112 (10%) Query: 4 AENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPE 63 A V P AA+ G A P PA PAG G A++ G+ P+ Sbjct: 294 APAVPPPAAAQNGGSAG-----AAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPK 348 Query: 64 SEVR-TEPAAEAEAASGPSESPS-----PPAAEELPGSHAEPPVPAQGEAPG 109 V+ PAA+ AASGP+ + + P LP A PP PA G G Sbjct: 349 RVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPP-PAPGTPTG 399 Score = 34.3 bits (77), Expect = 0.48 Identities = 38/110 (34%), Positives = 42/110 (38%), Gaps = 20/110 (18%) Query: 10 PEAAEE-----RAEPGQQQPAAEPPPAEGL-LRPAGPGAPEA---------AGTEASSEE 54 P AA E RA PG P PP+ L PAGP P A AG+ A Sbjct: 83 PGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPA 142 Query: 55 VGIAEAGPESEVR--TEPAAEAEAAS--GPSESPSP-PAAEELPGSHAEP 99 AGPE +PA A A+ GP P P P PG A P Sbjct: 143 AAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGP 192 Score = 33.5 bits (75), Expect = 0.81 Identities = 36/123 (29%), Positives = 41/123 (33%), Gaps = 20/123 (16%) Query: 40 PGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASGPSESPSPPAAEELPG----- 94 P PE A + + P PAA AE A G + P PPA PG Sbjct: 45 PRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEP-PPAGRARPGGGGPQ 103 Query: 95 -----SHAEPPVPAQGEAPGEQARDERSDSRAQ-----AVSEDAGGNE----GRAAEAEP 140 S P VPA P + R S A + A G E G A A P Sbjct: 104 RPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGP 163 Query: 141 RAL 143 AL Sbjct: 164 AAL 166 Score = 30.0 bits (66), Expect = 9.0 Identities = 28/118 (23%), Positives = 37/118 (31%), Gaps = 3/118 (2%) Query: 7 VAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEV 66 + P A P P+ PP A PA P + G P + Sbjct: 238 IQTPPFVGAAAPPAPAAPS--PPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAP 295 Query: 67 RTEPAAEAEAASGPSESPSP-PAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQA 123 P A A+ +P+P PAA G +P A AP + E QA Sbjct: 296 AVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQA 353 >gi|23503317 coiled-coil domain containing 96 [Homo sapiens] Length = 555 Score = 50.4 bits (119), Expect = 6e-06 Identities = 36/115 (31%), Positives = 53/115 (46%), Gaps = 7/115 (6%) Query: 61 GPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQ-GEAPGEQARDERSDS 119 G + E ++ +A+SGP SP P E P E +Q G A EQA + + Sbjct: 15 GGDGESLAARPSKIKASSGPPTSPEPGELESEPEEEEEEQAASQGGTAADEQAEAPKGLT 74 Query: 120 RAQAVSEDAGGNEGRAAEAEPRALENGD--ADEPSFSD----PEDFVDDVSEEEL 168 A+A E+ G GR AE +P E + A+EP+ + PE+ + EEL Sbjct: 75 AAEAAGEEGPGEPGRPAEPQPEPEEPAEVGAEEPAQPEPGAGPEELEAEAGAEEL 129 Score = 50.1 bits (118), Expect = 8e-06 Identities = 44/144 (30%), Positives = 59/144 (40%), Gaps = 8/144 (5%) Query: 10 PEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPE----SE 65 PE EE Q AA+ E P G A EAAG E E AE PE +E Sbjct: 47 PEEEEEEQAASQGGTAAD----EQAEAPKGLTAAEAAGEEGPGEPGRPAEPQPEPEEPAE 102 Query: 66 VRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVS 125 V E A+ E +GP E + AEEL + V Q P + +E + + +A + Sbjct: 103 VGAEEPAQPEPGAGPEELEAEAGAEELEQAAEGKEVRFQASLPLTRIDEEEAAAAPEAET 162 Query: 126 EDAGGNEGRAAEAEPRALENGDAD 149 E G E E + E+ + D Sbjct: 163 ERVEGEEEDKEETQRDGAESKERD 186 Score = 41.2 bits (95), Expect = 0.004 Identities = 41/173 (23%), Positives = 66/173 (38%), Gaps = 21/173 (12%) Query: 4 AENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGP---GAPEAAGTEASSEEVGIAEA 60 A A E E P + QP E P G PA P PE EA +EE + +A Sbjct: 75 AAEAAGEEGPGEPGRPAEPQPEPEEPAEVGAEEPAQPEPGAGPEELEAEAGAEE--LEQA 132 Query: 61 GPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSR 120 EVR + + + +P A E +GE E+ ++E Sbjct: 133 AEGKEVRFQASLPLTRIDEEEAAAAPEAETE----------RVEGE---EEDKEETQRDG 179 Query: 121 AQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFVDDVSEEELLGDVL 173 A++ D G ++ E R + ++ +S+ V + E++L D+L Sbjct: 180 AESKERDGEGRPAKSQEEGKRLYGRDEFEDLEWSEE---VQKLQEQQLRSDLL 229 Score = 34.3 bits (77), Expect = 0.48 Identities = 45/210 (21%), Positives = 75/210 (35%), Gaps = 19/210 (9%) Query: 12 AAEERAEPGQQ-----QPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEV 66 ++E +PG + AA P + P P +PE E+ EE +A + Sbjct: 4 SSEHTKDPGGEGGDGESLAARPSKIKASSGP--PTSPEPGELESEPEEEEEEQAASQGGT 61 Query: 67 RTEPAAEAE-----AASGPSESPSPPAAEELPGSHAEPPVPAQGE-----APGEQARDER 116 + AEA A + E P P P E P E PG + Sbjct: 62 AADEQAEAPKGLTAAEAAGEEGPGEPGRPAEPQPEPEEPAEVGAEEPAQPEPGAGPEELE 121 Query: 117 SDSRAQAVSEDAGGNEGRAAEAEP--RALENGDADEPSFSDPEDFVDDVSEEELLGDVLK 174 +++ A+ + + A G E R + P R E A P ++ +EE D + Sbjct: 122 AEAGAEELEQAAEGKEVRFQASLPLTRIDEEEAAAAPEAETERVEGEEEDKEETQRDGAE 181 Query: 175 DRPQEADGIDSVIVVDNVPQVGPDRLEKLK 204 + ++ +G + + G D E L+ Sbjct: 182 SKERDGEGRPAKSQEEGKRLYGRDEFEDLE 211 >gi|193083172 nuclear assembly factor 1 homolog isoform b [Homo sapiens] Length = 389 Score = 50.1 bits (118), Expect = 8e-06 Identities = 51/235 (21%), Positives = 88/235 (37%), Gaps = 40/235 (17%) Query: 19 PGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAAS 78 P P + P P + G+P+A T E P E +P A AA Sbjct: 27 PAAPSPGSAPVPGTQPPLQSFEGSPDAGQT---------VEVKPAGEQPLQPVLNAVAAG 77 Query: 79 GPSESPSPPAAEELPGSHAEPPVPAQ-GEAPGE-QARDERSDSRAQAVSEDAGGNEGRAA 136 P+ P PPA G P A+ AP + D SDS ++ S+ + + ++ Sbjct: 78 TPAPQPQPPAESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSS 137 Query: 137 EAE---------PRALENGDADEPSFSDPEDFVDDVSEEELLGDV--------------- 172 + P L +GD D + ++F +E LL ++ Sbjct: 138 SSSSSSSSCISLPPVLSDGDDDLQIEKENKNFPLKTKDELLLNELPSVEELTIILPEDIE 197 Query: 173 LKDRPQEADGIDSVIVVDNVPQVGPDRLEKL-----KNVIHKIFSKFGKITNDFY 222 LK + I+ +++++++ + P E + + KIF FG + + FY Sbjct: 198 LKPLGMVSSIIEQLVIIESMTNLPPVNEETVIFKSDRQAAGKIFEIFGPVAHPFY 252 >gi|193083157 nuclear assembly factor 1 homolog isoform a [Homo sapiens] Length = 494 Score = 50.1 bits (118), Expect = 8e-06 Identities = 51/235 (21%), Positives = 88/235 (37%), Gaps = 40/235 (17%) Query: 19 PGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAAS 78 P P + P P + G+P+A T E P E +P A AA Sbjct: 27 PAAPSPGSAPVPGTQPPLQSFEGSPDAGQT---------VEVKPAGEQPLQPVLNAVAAG 77 Query: 79 GPSESPSPPAAEELPGSHAEPPVPAQ-GEAPGE-QARDERSDSRAQAVSEDAGGNEGRAA 136 P+ P PPA G P A+ AP + D SDS ++ S+ + + ++ Sbjct: 78 TPAPQPQPPAESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSS 137 Query: 137 EAE---------PRALENGDADEPSFSDPEDFVDDVSEEELLGDV--------------- 172 + P L +GD D + ++F +E LL ++ Sbjct: 138 SSSSSSSSCISLPPVLSDGDDDLQIEKENKNFPLKTKDELLLNELPSVEELTIILPEDIE 197 Query: 173 LKDRPQEADGIDSVIVVDNVPQVGPDRLEKL-----KNVIHKIFSKFGKITNDFY 222 LK + I+ +++++++ + P E + + KIF FG + + FY Sbjct: 198 LKPLGMVSSIIEQLVIIESMTNLPPVNEETVIFKSDRQAAGKIFEIFGPVAHPFY 252 >gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] Length = 2944 Score = 49.3 bits (116), Expect = 1e-05 Identities = 45/164 (27%), Positives = 58/164 (35%), Gaps = 17/164 (10%) Query: 7 VAVPEAAEERAEPGQQQPAAE-----PPPAEGLLRPAGP-------GAPEAAGTEASSEE 54 V P R E GQ P+ E PP EG+ P GP G P A+G + + Sbjct: 2403 VGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGD 2462 Query: 55 VGIAEAGPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARD 114 G+ GP E R EP E G P PGS E +G+ + Sbjct: 2463 PGVGLPGPRGE-RGEPGIRGE--DGRPGQEGPRGLTGPPGSRGER--GEKGDVGSAGLKG 2517 Query: 115 ERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPED 158 ++ DS G +G E PR L+ DP D Sbjct: 2518 DKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGD 2561 Score = 48.5 bits (114), Expect = 2e-05 Identities = 44/146 (30%), Positives = 50/146 (34%), Gaps = 15/146 (10%) Query: 13 AEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGI----AEAGPESEVRT 68 A +PG Q P P P G P PGAP AG G+ E GP T Sbjct: 2161 AGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLT 2220 Query: 69 EPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQ-GEA--PGEQARDERSDSRAQAVS 125 P +G P PP L G P +P Q GE PG RD S S Sbjct: 2221 GP-------TGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGS 2273 Query: 126 EDAGGNEGRAAEAEPRALENGDADEP 151 G+ G P+ E G P Sbjct: 2274 PGVPGSPGLPGPVGPKG-EPGPTGAP 2298 Score = 38.5 bits (88), Expect = 0.025 Identities = 34/124 (27%), Positives = 47/124 (37%), Gaps = 15/124 (12%) Query: 16 RAEPGQQQPAAE-----PPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEP 70 + +PG + PA E PP +G R G P AAG + G +AG Sbjct: 1757 QGDPGVRGPAGEKGDRGPPGLDG--RSGLDGKPGAAGPSGPNGAAG--KAGDPGRDGLPG 1812 Query: 71 AAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGG 130 + GPS PP PG +P + + PG+ D R + + A G Sbjct: 1813 LRGEQGLPGPS---GPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDS---GASG 1866 Query: 131 NEGR 134 EGR Sbjct: 1867 REGR 1870 Score = 36.6 bits (83), Expect = 0.096 Identities = 37/132 (28%), Positives = 46/132 (34%), Gaps = 20/132 (15%) Query: 19 PGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVG-IAEAGPESE--VRTEPAAEA- 74 PG P P L P PGAP G + G + + GP E + P E Sbjct: 2376 PGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGI 2435 Query: 75 ---EAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGGN 131 GP S PP A L G +P V G R ER + + G Sbjct: 2436 PGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPG------PRGERGEPGIR-------GE 2482 Query: 132 EGRAAEAEPRAL 143 +GR + PR L Sbjct: 2483 DGRPGQEGPRGL 2494 Score = 36.2 bits (82), Expect = 0.13 Identities = 44/165 (26%), Positives = 53/165 (32%), Gaps = 21/165 (12%) Query: 10 PEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTE 69 P + +PG P+ P P L P G P GT ++ E GP Sbjct: 1361 PGLPGRKGDPG---PSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGG 1417 Query: 70 PAAEAEAASGPSESPSPPAAEELPGSHAE--------PPVPAQGEAPGEQ-------ARD 114 A G SP P PG E P +P Q +PGEQ A Sbjct: 1418 IAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIG 1477 Query: 115 ERSDSRAQAVSEDAG--GNEGRAAEAEPRALENGDADEPSFSDPE 157 + D +AG G G A R L G A P PE Sbjct: 1478 PKGDRGFPGPLGEAGEKGERGPPGPAGSRGLP-GVAGRPGAKGPE 1521 Score = 35.0 bits (79), Expect = 0.28 Identities = 31/121 (25%), Positives = 41/121 (33%), Gaps = 8/121 (6%) Query: 21 QQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVG-IAEAGPESEVRTEPAAEAEAASG 79 Q QP A P + P PG G +VG + G + E + A + G Sbjct: 2586 QGQPGAAGIPGD----PGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKG 2641 Query: 80 PSESPSPPAAEELPGSHAE---PPVPAQGEAPGEQARDERSDSRAQAVSEDAGGNEGRAA 136 PP L G E P VP Q APG++ R G++G Sbjct: 2642 DKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKG 2701 Query: 137 E 137 E Sbjct: 2702 E 2702 Score = 34.7 bits (78), Expect = 0.37 Identities = 26/93 (27%), Positives = 33/93 (35%), Gaps = 5/93 (5%) Query: 23 QPAAEPPPAEGLLRPAG----PGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAE-AEAA 77 +P PP GL P G PG P +G G+ E+ P + A Sbjct: 2208 EPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGK 2267 Query: 78 SGPSESPSPPAAEELPGSHAEPPVPAQGEAPGE 110 G SP P + LPG P APG+ Sbjct: 2268 DGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQ 2300 Score = 32.7 bits (73), Expect = 1.4 Identities = 35/144 (24%), Positives = 48/144 (33%), Gaps = 14/144 (9%) Query: 9 VPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVG----IAEAGPES 64 +P + E G + P EP ++ GPG P G S G + + GP Sbjct: 1330 LPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRG 1389 Query: 65 EVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQA-------RDERS 117 P + G PP E + EP +P +PG Q + E+ Sbjct: 1390 PPGL-PGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKG 1448 Query: 118 DSRAQAVSEDAGGNEGRAAEAEPR 141 DS A G G E PR Sbjct: 1449 DSEDGA--PGLPGQPGSPGEQGPR 1470 Score = 31.6 bits (70), Expect = 3.1 Identities = 37/153 (24%), Positives = 50/153 (32%), Gaps = 22/153 (14%) Query: 15 ERAEPGQQQPAAEPPPA-------EGLLRPAGP-GAPEAAGTEASSEEVGIAEAGPESEV 66 E+ EPG+ A PA +G + PAGP GA G V + GP+ + Sbjct: 1532 EKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDP 1591 Query: 67 RTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSE 126 +GP PP G +P P G + RD + Sbjct: 1592 GDRGPIGLTGRAGPPGDSGPP------GEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPP 1645 Query: 127 DAGGNEGRAAEAEPRAL--------ENGDADEP 151 G G+A E R E GD +P Sbjct: 1646 GDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDP 1678 Score = 30.0 bits (66), Expect = 9.0 Identities = 29/102 (28%), Positives = 35/102 (34%), Gaps = 8/102 (7%) Query: 3 DAENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGP-GAPEAAGTEASSEEVGIAEAG 61 D+E+ A P + PG+Q P P G + P G G P G E G G Sbjct: 1449 DSEDGA-PGLPGQPGSPGEQGPRGPP----GAIGPKGDRGFPGPLGEAGEKGERG--PPG 1501 Query: 62 PESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPA 103 P A A GP P P + G P PA Sbjct: 1502 PAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPA 1543 Score = 30.0 bits (66), Expect = 9.0 Identities = 26/101 (25%), Positives = 38/101 (37%), Gaps = 5/101 (4%) Query: 10 PEAAEERAEPGQQ-QPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRT 68 P ER E G++ + + PP GL P PG P G + S +E G +G + Sbjct: 2057 PGERGERGEKGERGEQGRDGPP--GL--PGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGL 2112 Query: 69 EPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPG 109 + A ++G + G EP Q PG Sbjct: 2113 KGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPG 2153 >gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] Length = 1499 Score = 48.1 bits (113), Expect = 3e-05 Identities = 42/145 (28%), Positives = 50/145 (34%), Gaps = 11/145 (7%) Query: 7 VAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGP----GAPEAAGTEASSEEVGIAEAGP 62 V +P ER PG PA P G + P G G P G S+ VG E GP Sbjct: 995 VGMPGQRGERGMPGLPGPAGTP----GKVGPTGATGDKGPPGPVGPPGSNGPVG--EPGP 1048 Query: 63 ESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQ 122 E + + A G P LPGS P P APG+ + SR Sbjct: 1049 EGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGP 1108 Query: 123 AVSEDAGGNEGRAAEAEPRALENGD 147 G G PR + GD Sbjct: 1109 IGPPGRAGKRGLPGPQGPRG-DKGD 1132 Score = 35.8 bits (81), Expect = 0.16 Identities = 42/159 (26%), Positives = 52/159 (32%), Gaps = 15/159 (9%) Query: 19 PGQQQPAAEP--PPAEGLLRPAGP-GAPEAAGTEASSEEVGIA-EAGPESE--VRTEPAA 72 PG P E P GL+ P G G P + G + VG A GP+ + V+ EP Sbjct: 806 PGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGE 865 Query: 73 EAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGGNE 132 + G + SP P PG H VP G Q + A G Sbjct: 866 PGQ--KGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPA 923 Query: 133 GRAAEAEPRALENGDADEPSFSDPEDFVDDVSEEELLGD 171 G A G EP P D +GD Sbjct: 924 GAPGPA-------GPLGEPGKEGPPGLRGDPGSHGRVGD 955 Score = 35.4 bits (80), Expect = 0.21 Identities = 38/122 (31%), Positives = 43/122 (35%), Gaps = 20/122 (16%) Query: 10 PEAAEERAEPGQQQPAAEPPPAEGLLRPAGP----GAPEAAGTEASSEEVGIAEAGPESE 65 P E EPGQ+ A P P +GL GP G P G + G A P S Sbjct: 857 PGVKGEPGEPGQKGDAGSPGP-QGLAGSPGPHGPNGVPGLKGGRGTQGPPG-ATGFPGSA 914 Query: 66 VRTEP--AAEAEAASGPSESP---SPPAAEELPGSHAE---------PPVPAQGEAPGEQ 111 R P A A +GP P PP PGSH P P PGE Sbjct: 915 GRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGED 974 Query: 112 AR 113 + Sbjct: 975 GQ 976 Score = 33.9 bits (76), Expect = 0.62 Identities = 29/91 (31%), Positives = 34/91 (37%), Gaps = 14/91 (15%) Query: 29 PPAEGLLRPAG----PGAPEAAGTEASSEEVGI----AEAGPESEVRTEPAAEAEAASGP 80 P + GL P G PG P AG + G E GP V A GP Sbjct: 611 PGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGP 670 Query: 81 SESPSPPAAEELPGSHAEPPVPAQGEAPGEQ 111 P P + LPG P P +G PG+Q Sbjct: 671 ---PGPTGFQGLPGP---PGPPGEGGKPGDQ 695 Score = 33.5 bits (75), Expect = 0.81 Identities = 36/148 (24%), Positives = 45/148 (30%), Gaps = 13/148 (8%) Query: 10 PEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVG-IAEAGPESEVRT 68 P +A PG PA P PA L P G P G S VG AGP Sbjct: 911 PGSAGRVGPPG---PAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGD 967 Query: 69 EPAAEAEAASGPSESPSPPAAE------ELPGSHAE---PPVPAQGEAPGEQARDERSDS 119 + + GP P P +PG E P +P PG+ + Sbjct: 968 KGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGD 1027 Query: 120 RAQAVSEDAGGNEGRAAEAEPRALENGD 147 + G+ G E P D Sbjct: 1028 KGPPGPVGPPGSNGPVGEPGPEGPAGND 1055 Score = 31.2 bits (69), Expect = 4.0 Identities = 32/126 (25%), Positives = 43/126 (34%), Gaps = 9/126 (7%) Query: 28 PPPAEGLLRPAGPGAPEAAGTEA-SSEEVGIAEAGPESEVRTEPAAEAEAASGPSESPSP 86 PP +G+ PG AGT + GI E G E + A GP P Sbjct: 757 PPGLQGM-----PGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGP 811 Query: 87 PAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAE-AEPRALEN 145 + PG P PG + + + + A + G G E EP + Sbjct: 812 TGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPG--QK 869 Query: 146 GDADEP 151 GDA P Sbjct: 870 GDAGSP 875 Score = 30.0 bits (66), Expect = 9.0 Identities = 29/123 (23%), Positives = 38/123 (30%), Gaps = 7/123 (5%) Query: 18 EPGQQQPAAEP--PPAEGLLRP-----AGPGAPEAAGTEASSEEVGIAEAGPESEVRTEP 70 +PG P P P +GL RP AG G++ + GP + Sbjct: 169 QPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQG 228 Query: 71 AAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGG 130 +GP P P GS P + GE R+ A S A G Sbjct: 229 QQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARG 288 Query: 131 NEG 133 G Sbjct: 289 FPG 291 >gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] Length = 825 Score = 48.1 bits (113), Expect = 3e-05 Identities = 69/241 (28%), Positives = 104/241 (43%), Gaps = 42/241 (17%) Query: 4 AENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGI------ 57 A+ V++ EA E P ++ AE A L A TEAS+EE Sbjct: 564 AKGVSIEEAPLELQPPSGEETTAEEASAAIQL---------LAATEASAEEAPAEVQPPP 614 Query: 58 AEAGPESEVRTEPAAEAEAASGP---SESPS---PPAAEELPGSHAEPPVPAQGEAPGEQ 111 AE P +EV+ PA EA A P E+P+ PP AEE P PP EAP E Sbjct: 615 AEEAP-AEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAE---EAPAEV 670 Query: 112 ARDERSDSRAQAVS---EDAGGNEGRAAEAEPRALENGDADEPS---FSDPEDFVDDVSE 165 ++ A+ S E+ E AA P A ++ A+E S S P D + ++E Sbjct: 671 QPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPA-DDVPAEEASVDKHSPPADLL--LTE 727 Query: 166 EELLGDV--------LKDRPQEADGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKI 217 E +G+ + P++ +++V PQV KL +V+ + +KF ++ Sbjct: 728 EFPIGEASAEVSPPPSEQTPEDEALVENVSTEFQSPQVAGIPAVKLGSVVLEGEAKFEEV 787 Query: 218 T 218 + Sbjct: 788 S 788 Score = 42.0 bits (97), Expect = 0.002 Identities = 44/155 (28%), Positives = 60/155 (38%), Gaps = 18/155 (11%) Query: 13 AEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSE-EVGIAEAGPESEVRTE-- 69 AEE + Q A EPP E P + E + EA +E + +AE E E Sbjct: 467 AEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQ 526 Query: 70 --PAAEAEAASGPSESPSP----PAAEELPGSHAEPPVPAQG--EAP-------GEQARD 114 A EA A P+E+ SP +AEE P P EAP GE+ Sbjct: 527 LLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTA 586 Query: 115 ERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDAD 149 E + + Q ++ E AE +P E A+ Sbjct: 587 EEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAE 621 Score = 40.4 bits (93), Expect = 0.007 Identities = 48/198 (24%), Positives = 71/198 (35%), Gaps = 18/198 (9%) Query: 1 MQDAENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSE-EVGIAE 59 + D + + EA E A Q A E P E P E EAS+E ++ A Sbjct: 421 LADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAAT 480 Query: 60 AGPESEVRTE---PAAEAEAASGPSESPSPPAAEELPGSHAEPPV-------------PA 103 P E E P +E +A P AEE A + PA Sbjct: 481 EPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPA 540 Query: 104 QGEAP-GEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFVDD 162 + ++P E+ E + + Q+ S E E +P + E A+E S + + Sbjct: 541 EAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATE 600 Query: 163 VSEEELLGDVLKDRPQEA 180 S EE +V +EA Sbjct: 601 ASAEEAPAEVQPPPAEEA 618 Score = 39.3 bits (90), Expect = 0.015 Identities = 56/198 (28%), Positives = 75/198 (37%), Gaps = 23/198 (11%) Query: 5 ENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEA-------------- 50 E V VP E A EPP E P E A +A Sbjct: 236 EEVTVPVVQEGSAVKKVASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQP 295 Query: 51 SSEEVGIAEAG---PESEVRTE--PAAEAEAASGPSESPSPPAAEELPGSH--AEPPVPA 103 S+EE AEA E+ V+ + PA EA P+E PP+AEE P AE P+ Sbjct: 296 STEETPDAEAATAVAENSVKVQPPPAEEAPLVEFPAEI-QPPSAEESPSVELLAEILPPS 354 Query: 104 QGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDAD-EPSFSDPEDFVDD 162 E+P E+ E A+ E R+ A+ +E E + + V+ Sbjct: 355 AEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEP 414 Query: 163 VSEEELLGDVLKDRPQEA 180 + EE L DV P+EA Sbjct: 415 PTVEETLADVQPLLPEEA 432 Score = 35.0 bits (79), Expect = 0.28 Identities = 46/187 (24%), Positives = 71/187 (37%), Gaps = 20/187 (10%) Query: 4 AENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPE 63 AE E E P ++ +E PPAE L P A ++ E E + Sbjct: 338 AEESPSVELLAEILPPSAEESPSEEPPAEIL----PPPAEKSPSVELLGEIRSPSAQKAP 393 Query: 64 SEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQA 123 EV+ P AE P++ P E L + +P +P EAP E+AR+ + + + Sbjct: 394 IEVQPLP-AEGALEEAPAKVEPPTVEETL--ADVQPLLPE--EAPREEARELQLSTAMET 448 Query: 124 VSEDAGGN-----------EGRAAEAEPRALENGDADEPSFSDPEDFVDDVSEEELLGDV 172 +E+A E +AE + A ADE ++ S EE +V Sbjct: 449 PAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEV 508 Query: 173 LKDRPQE 179 +E Sbjct: 509 QSPLAEE 515 Score = 33.1 bits (74), Expect = 1.1 Identities = 29/93 (31%), Positives = 36/93 (38%), Gaps = 6/93 (6%) Query: 2 QDAENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAG 61 ++A P AEE Q PA E P E L P A + EAS ++ + Sbjct: 664 EEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDK----HSP 719 Query: 62 PESEVRTE--PAAEAEAASGPSESPSPPAAEEL 92 P + TE P EA A P S P E L Sbjct: 720 PADLLLTEEFPIGEASAEVSPPPSEQTPEDEAL 752 >gi|117938759 GNAS complex locus XLas [Homo sapiens] Length = 1037 Score = 47.8 bits (112), Expect = 4e-05 Identities = 37/150 (24%), Positives = 55/150 (36%), Gaps = 8/150 (5%) Query: 3 DAENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGP 62 D ++ A PE + P A + PA P P++ A A P Sbjct: 401 DPDSGATPEDPDSGTAPADPDSGAFAADPDSGAAPAAPADPDSGAAPD-------APADP 453 Query: 63 ESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQ 122 +S + A+ +A + P E+P+ PAA E +H P P G A R+ + Sbjct: 454 DSGAAPDAPADPDAGAAP-EAPAAPAAAETRAAHVAPAAPDAGAPTAPAASATRAAQVRR 512 Query: 123 AVSEDAGGNEGRAAEAEPRALENGDADEPS 152 A S R P + E AD P+ Sbjct: 513 AASAAPASGARRKIHLRPPSPEIQAADPPT 542 Score = 37.7 bits (86), Expect = 0.043 Identities = 42/137 (30%), Positives = 53/137 (38%), Gaps = 27/137 (19%) Query: 24 PAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAE----AGPESEVRTEPAAEAEAASG 79 PAA PP L P G+P S G + +GP E+ + PA + Sbjct: 268 PAANAPP---LWVPGAIGSPSQEAVRPPSNFTGSSPWMEISGPPFEIGSAPAGVDDT--- 321 Query: 80 PSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAE 139 P SPP A L G PP+ G AP ++ R ER V E+A EG A Sbjct: 322 PVNMDSPPIA--LDG----PPIKVSG-APDKRERAERPP-----VEEEAAEMEGAA---- 365 Query: 140 PRALENGDADEPSFSDP 156 A E G P + P Sbjct: 366 -DAAEGGKVPSPGYGSP 381 Score = 37.0 bits (84), Expect = 0.074 Identities = 44/161 (27%), Positives = 63/161 (39%), Gaps = 16/161 (9%) Query: 10 PEAAEERAEPGQQQPAAE----PPPAEGLLRPA-GPGAPEA--AGTEASSEEVGIAEAGP 62 P+ E P ++ AAE AEG P+ G G+P A A + ++ A A P Sbjct: 343 PDKRERAERPPVEEEAAEMEGAADAAEGGKVPSPGYGSPAAGAASADTAARAAPAAPADP 402 Query: 63 ESEVRTEPAAEAEAASGPSESP--SPPAAEELPGSHAEPPVPAQGEAPGE----QARDER 116 +S E A + P + P + P + A+P A +AP + A D Sbjct: 403 DSGATPEDPDSGTAPADPDSGAFAADPDSGAAPAAPADPDSGAAPDAPADPDSGAAPDAP 462 Query: 117 SDSRAQAVSE---DAGGNEGRAAEAEPRALENGDADEPSFS 154 +D A A E E RAA P A + G P+ S Sbjct: 463 ADPDAGAAPEAPAAPAAAETRAAHVAPAAPDAGAPTAPAAS 503 Score = 35.0 bits (79), Expect = 0.28 Identities = 32/113 (28%), Positives = 42/113 (37%), Gaps = 14/113 (12%) Query: 58 AEAGPESEVRTEPAAEAEAASGPSESPSP-------------PAAEELPGSHAEPPVPAQ 104 AE P E E A+AA G + PSP AA P + A+P A Sbjct: 349 AERPPVEEEAAEMEGAADAAEG-GKVPSPGYGSPAAGAASADTAARAAPAAPADPDSGAT 407 Query: 105 GEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPE 157 E P DS A A D+G A+ + A + AD S + P+ Sbjct: 408 PEDPDSGTAPADPDSGAFAADPDSGAAPAAPADPDSGAAPDAPADPDSGAAPD 460 Score = 32.3 bits (72), Expect = 1.8 Identities = 21/52 (40%), Positives = 24/52 (46%), Gaps = 4/52 (7%) Query: 59 EAGPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEP-PVPAQGEAPG 109 E G + E +P EA A+ P PSP E H EP PV GEA G Sbjct: 21 EIGEQPE---QPPLEAPGAAAPGAGPSPAEEMETEPPHNEPIPVENDGEACG 69 >gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] Length = 2217 Score = 47.8 bits (112), Expect = 4e-05 Identities = 39/115 (33%), Positives = 53/115 (46%), Gaps = 13/115 (11%) Query: 17 AEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPE---SEVRTEPAAE 73 AE + +PAA P PA + +P PGAP AG E VG E GP+ + V T PA + Sbjct: 86 AERARGRPAA-PAPAALVAQPGAPGAPADAGPEP----VGTQEPGPDPIAAAVETAPAPD 140 Query: 74 AEAASGPSESPSPPAAEELPGSHAEPPVPAQGEA-PGEQARDERSDSRAQAVSED 127 GP E + +E G+ P P + E+ D+ D +A A S D Sbjct: 141 ----GGPREEAAATVRKEDEGAAEAKPEPGRTRRDEPEEEEDDEDDLKAVATSLD 191 Score = 38.1 bits (87), Expect = 0.033 Identities = 31/96 (32%), Positives = 38/96 (39%), Gaps = 24/96 (25%) Query: 28 PPPAEGLLRPAG-PGAPEAAGTEASSEE----------------VGIAEAGPESEVRTEP 70 P PA G AG PG P+ +E + + VG+A P E Sbjct: 1407 PEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPE----- 1461 Query: 71 AAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGE 106 AA AS P E PPA E P H+ P PA G+ Sbjct: 1462 AASTRDASAPREPLPPPAPE--PSPHSGTPQPALGQ 1495 Score = 32.7 bits (73), Expect = 1.4 Identities = 31/121 (25%), Positives = 45/121 (37%), Gaps = 6/121 (4%) Query: 19 PGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAAS 78 P + PA E P + L P PEA+ A ++ ++ P + ++A Sbjct: 1317 PVAEHPAPEAPESSPPL-PLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQA---- 1371 Query: 79 GPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEA 138 GPS P P A P S +P G AP E + A G +G +E Sbjct: 1372 GPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAG-GPGTPQGLTSEL 1430 Query: 139 E 139 E Sbjct: 1431 E 1431 Score = 30.8 bits (68), Expect = 5.3 Identities = 38/135 (28%), Positives = 54/135 (40%), Gaps = 19/135 (14%) Query: 10 PEAAEERAEPGQQQPAAEPPP---AEGLLRPAG----PGAPEAAGTEASSEEVGIAE--A 60 PEA+++ A Q + E P ++ LL AG PGAP A +S + + A Sbjct: 1340 PEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSSPPVTALPQDGA 1399 Query: 61 GPESEVRTEPAAEAEAASGPSESP---------SPPAAEELPGSHAEPPVPAQGEAPGEQ 111 P + EPA+ + +G +P S P AE A P+ G AP Sbjct: 1400 APATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPL-VVGLAPCTP 1458 Query: 112 ARDERSDSRAQAVSE 126 A + S A A E Sbjct: 1459 APEAASTRDASAPRE 1473 Score = 30.4 bits (67), Expect = 6.9 Identities = 31/100 (31%), Positives = 40/100 (40%), Gaps = 25/100 (25%) Query: 10 PEAAEERAEPGQQQP----AAEPPPAEGLLRPA----GPGAPEAAGTEASSEEVGIAEAG 61 PEAA R ++P A EP P G +PA P P A G V +A Sbjct: 1460 PEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGA------VSLAT-- 1511 Query: 62 PESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPV 101 S++ + P GP+ P PP+A E G P V Sbjct: 1512 --SQLPSPPL-------GPTVPPQPPSALESDGEGPPPRV 1542 >gi|153070260 myristoylated alanine-rich protein kinase C substrate [Homo sapiens] Length = 332 Score = 47.4 bits (111), Expect = 5e-05 Identities = 44/142 (30%), Positives = 65/142 (45%), Gaps = 14/142 (9%) Query: 2 QDAENVAVPEAAEERAEPGQQQPAAEPPPAEGL----LRPAGPGAPEAAGTEASSEEVGI 57 Q ++ A EAA ER PG+ A+ P A G ++ G +P AA + A EE+ Sbjct: 4 QFSKTAAKGEAAAER--PGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAK-EELQA 60 Query: 58 AEAGPESEVRTEPAAEAEAASGPSES----PSPPAAEELPGSHAEPPVPAQGEA--PGEQ 111 + P ++ + EPAA A+ PS + P+ AA E S E PA+GEA PG Sbjct: 61 NGSAPAAD-KEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSP 119 Query: 112 ARDERSDSRAQAVSEDAGGNEG 133 E + A + + +G Sbjct: 120 TAAEGEAASAASSTSSPKAEDG 141 Score = 41.6 bits (96), Expect = 0.003 Identities = 53/202 (26%), Positives = 72/202 (35%), Gaps = 33/202 (16%) Query: 8 AVPEAAE----------------ERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEAS 51 A P AAE ++ EP A P A PA APEA + Sbjct: 45 ASPAAAESGAKEELQANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVE 104 Query: 52 SEEVGIAEAGPESEVRTEPAAEAEAASGPSESPSPPAAE-ELPGSHAEPP---------- 100 E EA +E + AAE EAAS S + SP A + P E P Sbjct: 105 KEAPAEGEA---AEPGSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFK 161 Query: 101 --VPAQGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPED 158 G + + ++ A+A + + GG + A A A E G A + P + Sbjct: 162 KSFKLSGFSFKKNKKEAGEGGEAEAPAAE-GGKDEAAGGAAAAAAEAGAASGEQAAAPGE 220 Query: 159 FVDDVSEEELLGDVLKDRPQEA 180 E GD + +PQEA Sbjct: 221 EAAAGEEGAAGGDPQEAKPQEA 242 Score = 38.9 bits (89), Expect = 0.019 Identities = 36/110 (32%), Positives = 48/110 (43%), Gaps = 15/110 (13%) Query: 12 AAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPA 71 A EE A G Q E P E + P P P + T+A+ E + E E + A Sbjct: 224 AGEEGAAGGDPQ---EAKPQEAAVAPEKP--PASDETKAAEEPSKVEEKKAEEAGASAAA 278 Query: 72 AEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGE----APGEQARDERS 117 EA +A+GP +PP E P AE P A AP ++A+ E S Sbjct: 279 CEAPSAAGPG---APPEQEAAP---AEEPAAAAASSACAAPSQEAQPECS 322 Score = 38.1 bits (87), Expect = 0.033 Identities = 36/129 (27%), Positives = 50/129 (38%), Gaps = 12/129 (9%) Query: 11 EAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTE---------ASSEEVGIAEAG 61 E ++ A G AAE A G + A PG AAG E A +E +A Sbjct: 190 EGGKDEAAGGAAAAAAEAGAASGE-QAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEK 248 Query: 62 PESEVRTEPAAEAEAASGPS--ESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDS 119 P + T+ A E E+ + AA E P + P Q AP E+ + S Sbjct: 249 PPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASS 308 Query: 120 RAQAVSEDA 128 A S++A Sbjct: 309 ACAAPSQEA 317 Score = 37.4 bits (85), Expect = 0.056 Identities = 31/104 (29%), Positives = 44/104 (42%), Gaps = 10/104 (9%) Query: 15 ERAEPGQQQPAAEPPPAEGLLRPAG-PGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAE 73 + A+P + A E PPA + A P E E +EE G + A E+ P A Sbjct: 235 QEAKPQEAAVAPEKPPASDETKAAEEPSKVE----EKKAEEAGASAAACEAPSAAGPGAP 290 Query: 74 AEAASGPSESPSPPAAEE---LPGSHAEPPVPAQGEAPGEQARD 114 E + P+E P+ AA P A+P EAP +A + Sbjct: 291 PEQEAAPAEEPAAAAASSACAAPSQEAQP--ECSPEAPPAEAAE 332 Score = 35.4 bits (80), Expect = 0.21 Identities = 30/118 (25%), Positives = 46/118 (38%), Gaps = 4/118 (3%) Query: 37 PAGPGAPE--AAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASGPSESPSPPAAEELPG 94 PA G + A G A++ E G A + E AA E A+G + P +E Sbjct: 187 PAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKP--QEAAV 244 Query: 95 SHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDADEPS 152 + +PP + +A E ++ E + S A A P E A+EP+ Sbjct: 245 APEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPA 302 Score = 33.9 bits (76), Expect = 0.62 Identities = 28/106 (26%), Positives = 39/106 (36%), Gaps = 10/106 (9%) Query: 49 EASSEEVGIAEAGPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAP 108 E E AE G + AA AEA + E + P E G A Sbjct: 180 EGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEG---------AA 230 Query: 109 GEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDADEPSFS 154 G ++ + A A + +E +AAE EP +E A+E S Sbjct: 231 GGDPQEAKPQEAAVAPEKPPASDETKAAE-EPSKVEEKKAEEAGAS 275 >gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Homo sapiens] Length = 305 Score = 46.6 bits (109), Expect = 9e-05 Identities = 51/184 (27%), Positives = 67/184 (36%), Gaps = 15/184 (8%) Query: 11 EAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEP 70 EA E+ PA+ PPP L P A A+ V + P P Sbjct: 120 EAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAP 179 Query: 71 AAEAEAASGPSESPSP-PAAEELPGSHAEPPVPA-QGEAPGEQARDERSDSRAQAVSEDA 128 A AA P+ +P+P PA P A P A QG G++ ++ +D +S Sbjct: 180 APAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGIS--- 236 Query: 129 GGNEGRAAEAEPRALENGDA----DEPSFSDPEDFVDDVSEEELLGDVLK--DRPQEADG 182 GR A A NG A P SD + E+ GDV P A G Sbjct: 237 ----GRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPG 292 Query: 183 IDSV 186 + SV Sbjct: 293 VGSV 296 Score = 33.5 bits (75), Expect = 0.81 Identities = 42/198 (21%), Positives = 72/198 (36%), Gaps = 29/198 (14%) Query: 3 DAENVAVPEAAEERAEPGQQQPAAEPPP---AEGLLRPAGPGAPEAAGTEASSEEVGIAE 59 + ++ +VP E + G+ + P P A + P P A G E + E++ Sbjct: 70 EVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQL---P 126 Query: 60 AGPESEVRTEPAAEAEAASGPSESPSP---------------PAAEELPGSHAEP----- 99 + P + P A P+ +P+P PA P P Sbjct: 127 SVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAA 186 Query: 100 PVPAQGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRA--LENGDADEPSFSDPE 157 P PA AP + A S + G N+G+ + EP A L +G + P+ Sbjct: 187 PAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQ-EPLADQLHSGISGRPAAGTAA 245 Query: 158 DFVDDVSEEELLGDVLKD 175 + + ++L G ++ D Sbjct: 246 ASANGAAIKKLSGPLISD 263 >gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Homo sapiens] Length = 305 Score = 46.6 bits (109), Expect = 9e-05 Identities = 51/184 (27%), Positives = 67/184 (36%), Gaps = 15/184 (8%) Query: 11 EAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEP 70 EA E+ PA+ PPP L P A A+ V + P P Sbjct: 120 EAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAP 179 Query: 71 AAEAEAASGPSESPSP-PAAEELPGSHAEPPVPA-QGEAPGEQARDERSDSRAQAVSEDA 128 A AA P+ +P+P PA P A P A QG G++ ++ +D +S Sbjct: 180 APAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGIS--- 236 Query: 129 GGNEGRAAEAEPRALENGDA----DEPSFSDPEDFVDDVSEEELLGDVLK--DRPQEADG 182 GR A A NG A P SD + E+ GDV P A G Sbjct: 237 ----GRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPG 292 Query: 183 IDSV 186 + SV Sbjct: 293 VGSV 296 Score = 33.5 bits (75), Expect = 0.81 Identities = 42/198 (21%), Positives = 72/198 (36%), Gaps = 29/198 (14%) Query: 3 DAENVAVPEAAEERAEPGQQQPAAEPPP---AEGLLRPAGPGAPEAAGTEASSEEVGIAE 59 + ++ +VP E + G+ + P P A + P P A G E + E++ Sbjct: 70 EVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQL---P 126 Query: 60 AGPESEVRTEPAAEAEAASGPSESPSP---------------PAAEELPGSHAEP----- 99 + P + P A P+ +P+P PA P P Sbjct: 127 SVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAA 186 Query: 100 PVPAQGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRA--LENGDADEPSFSDPE 157 P PA AP + A S + G N+G+ + EP A L +G + P+ Sbjct: 187 PAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQ-EPLADQLHSGISGRPAAGTAA 245 Query: 158 DFVDDVSEEELLGDVLKD 175 + + ++L G ++ D Sbjct: 246 ASANGAAIKKLSGPLISD 263 >gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo sapiens] Length = 316 Score = 46.6 bits (109), Expect = 9e-05 Identities = 51/184 (27%), Positives = 67/184 (36%), Gaps = 15/184 (8%) Query: 11 EAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEP 70 EA E+ PA+ PPP L P A A+ V + P P Sbjct: 131 EAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAP 190 Query: 71 AAEAEAASGPSESPSP-PAAEELPGSHAEPPVPA-QGEAPGEQARDERSDSRAQAVSEDA 128 A AA P+ +P+P PA P A P A QG G++ ++ +D +S Sbjct: 191 APAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGIS--- 247 Query: 129 GGNEGRAAEAEPRALENGDA----DEPSFSDPEDFVDDVSEEELLGDVLK--DRPQEADG 182 GR A A NG A P SD + E+ GDV P A G Sbjct: 248 ----GRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPG 303 Query: 183 IDSV 186 + SV Sbjct: 304 VGSV 307 Score = 33.5 bits (75), Expect = 0.81 Identities = 42/198 (21%), Positives = 72/198 (36%), Gaps = 29/198 (14%) Query: 3 DAENVAVPEAAEERAEPGQQQPAAEPPP---AEGLLRPAGPGAPEAAGTEASSEEVGIAE 59 + ++ +VP E + G+ + P P A + P P A G E + E++ Sbjct: 81 EVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQL---P 137 Query: 60 AGPESEVRTEPAAEAEAASGPSESPSP---------------PAAEELPGSHAEP----- 99 + P + P A P+ +P+P PA P P Sbjct: 138 SVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAA 197 Query: 100 PVPAQGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRA--LENGDADEPSFSDPE 157 P PA AP + A S + G N+G+ + EP A L +G + P+ Sbjct: 198 PAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQ-EPLADQLHSGISGRPAAGTAA 256 Query: 158 DFVDDVSEEELLGDVLKD 175 + + ++L G ++ D Sbjct: 257 ASANGAAIKKLSGPLISD 274 >gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 [Homo sapiens] Length = 916 Score = 46.6 bits (109), Expect = 9e-05 Identities = 39/145 (26%), Positives = 57/145 (39%), Gaps = 8/145 (5%) Query: 7 VAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEV 66 V++ E +E AE +++P AE P APE E EE E E E Sbjct: 482 VSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEE---EEGQEEEEE 538 Query: 67 RTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSE 126 E A +A G SE EE E + EA GE+A + + + + + SE Sbjct: 539 EDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGE----TEAEAEGEEA-EAKEEKKVEEKSE 593 Query: 127 DAGGNEGRAAEAEPRALENGDADEP 151 + E A+A+ E + P Sbjct: 594 EVATKEELVADAKVEKPEKAKSPVP 618 Score = 40.0 bits (92), Expect = 0.009 Identities = 39/142 (27%), Positives = 59/142 (41%), Gaps = 14/142 (9%) Query: 50 ASSEEVGIA------EAGPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPA 103 A +EE+ ++ EA E E EP AE E + +SP A E+ E Sbjct: 475 AITEELAVSMKEEKKEAAEEKE--EEPEAEEEEVAA-KKSPVKATAPEVKEEEGEKEEEE 531 Query: 104 QGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFVDDV 163 E E+ +SD + SE G +E E E E E + + E V++ Sbjct: 532 GQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEK 591 Query: 164 SE-----EELLGDVLKDRPQEA 180 SE EEL+ D ++P++A Sbjct: 592 SEEVATKEELVADAKVEKPEKA 613 >gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 [Homo sapiens] Length = 540 Score = 46.6 bits (109), Expect = 9e-05 Identities = 39/145 (26%), Positives = 57/145 (39%), Gaps = 8/145 (5%) Query: 7 VAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEV 66 V++ E +E AE +++P AE P APE E EE E E E Sbjct: 106 VSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEE---EEGQEEEEE 162 Query: 67 RTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSE 126 E A +A G SE EE E + EA GE+A + + + + + SE Sbjct: 163 EDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGE----TEAEAEGEEA-EAKEEKKVEEKSE 217 Query: 127 DAGGNEGRAAEAEPRALENGDADEP 151 + E A+A+ E + P Sbjct: 218 EVATKEELVADAKVEKPEKAKSPVP 242 Score = 40.0 bits (92), Expect = 0.009 Identities = 39/142 (27%), Positives = 59/142 (41%), Gaps = 14/142 (9%) Query: 50 ASSEEVGIA------EAGPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPA 103 A +EE+ ++ EA E E EP AE E + +SP A E+ E Sbjct: 99 AITEELAVSMKEEKKEAAEEKE--EEPEAEEEEVAA-KKSPVKATAPEVKEEEGEKEEEE 155 Query: 104 QGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFVDDV 163 E E+ +SD + SE G +E E E E E + + E V++ Sbjct: 156 GQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEK 215 Query: 164 SE-----EELLGDVLKDRPQEA 180 SE EEL+ D ++P++A Sbjct: 216 SEEVATKEELVADAKVEKPEKA 237 >gi|117938310 sine oculis binding protein homolog [Homo sapiens] Length = 873 Score = 46.6 bits (109), Expect = 9e-05 Identities = 55/196 (28%), Positives = 74/196 (37%), Gaps = 23/196 (11%) Query: 10 PEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTE 69 P AAE R G + PP A GPGAP AG EA++ I R Sbjct: 682 PSAAERRTCGGCRDGHCSPPAAGD----PGPGAP--AGPEAAAACNVIVNG-----TRGA 730 Query: 70 PAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAG 129 A A++A P E P PP P P PA E E ++ S E A Sbjct: 731 AAEGAKSAEPPPEQPPPPPPPAPPKKLLSPEEPAVSEL--ESVKENNCASNCHLDGEAAK 788 Query: 130 GNEGRAAEAEPRALENGDADEPSFSDP--EDFVDDVSEEELLGDVLK--DRPQEADGIDS 185 G AL GD +P+ ++P ED + G V++ +P E + Sbjct: 789 KLMGE------EALAGGDKSDPNLNNPADEDHAYALRMLPKTGCVIQPVPKPAEKAAMAP 842 Query: 186 VIVVDNVPQVGPDRLE 201 I+ + GP+ LE Sbjct: 843 CIISSPMLSAGPEDLE 858 >gi|140972063 protein phosphatase 1, regulatory subunit 9B [Homo sapiens] Length = 817 Score = 46.2 bits (108), Expect = 1e-04 Identities = 50/162 (30%), Positives = 66/162 (40%), Gaps = 22/162 (13%) Query: 12 AAEERAEPGQQQP-----AAEPPPAEGLLRPAGPGAPEAAG-TEASSEEVGIAEAGPESE 65 A +ER GQQ P A PPP +R P E +G +EA S + +A E Sbjct: 267 AEKERCPAGQQPPQHRVAPARPPPKPREVRKIKPVEVEESGESEAESAPGEVIQA----E 322 Query: 66 VRTEPAAE-----AEAASGPSESPSPPAAEELPGSHAEPPV--PAQGEAPGEQARDERSD 118 V A E A AAS E P AA E + PP G AP + A +E + Sbjct: 323 VTVHAALENGSTVATAASPAPEEPKAQAAPEKEAAAVAPPERGVGNGRAP-DVAPEEVDE 381 Query: 119 SRAQAVSE----DAGGNEGRAAEAEPRALENGDADEPSFSDP 156 S+ + SE D G ++ ALE D D+ +P Sbjct: 382 SKKEDFSEADLVDVSAYSGLGEDSAGSALEEDDEDDEEDGEP 423 Score = 35.4 bits (80), Expect = 0.21 Identities = 32/125 (25%), Positives = 48/125 (38%), Gaps = 10/125 (8%) Query: 39 GPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASG--PSESPSPPAAEELPGSH 96 GPG P AAG + ++ S V P A SG P+E PA ++ P Sbjct: 227 GPGLPRAAGVPQVNSKL----VSKRSRVFQPPPPPPPAPSGDAPAEKERCPAGQQPPQHR 282 Query: 97 AEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRALENGD----ADEPS 152 P P + + + ++ +E A G +A ALENG A P+ Sbjct: 283 VAPARPPPKPREVRKIKPVEVEESGESEAESAPGEVIQAEVTVHAALENGSTVATAASPA 342 Query: 153 FSDPE 157 +P+ Sbjct: 343 PEEPK 347 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 46.2 bits (108), Expect = 1e-04 Identities = 32/85 (37%), Positives = 38/85 (44%), Gaps = 4/85 (4%) Query: 24 PAAEPP-PAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASGPSE 82 PAA PP P GL P+ GAP S + G+A P+ T PAA + G Sbjct: 1175 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKG-APTTPAATPPSPKGGLA 1233 Query: 83 SPSPPAAEELPGSHAEPPVPAQGEA 107 +PSP A P A PP P G A Sbjct: 1234 TPSPKGAPTTPA--ATPPSPKGGPA 1256 Score = 43.9 bits (102), Expect = 6e-04 Identities = 32/85 (37%), Positives = 37/85 (43%), Gaps = 4/85 (4%) Query: 24 PAAEPP-PAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASGPSE 82 PAA PP P GL P GAP S + G+A P+ T PAA + G Sbjct: 1129 PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKG-APTTPAATPPSPKGGLA 1187 Query: 83 SPSPPAAEELPGSHAEPPVPAQGEA 107 +PSP A P A PP P G A Sbjct: 1188 TPSPKGAPTTPA--ATPPSPKGGLA 1210 Score = 43.1 bits (100), Expect = 0.001 Identities = 32/86 (37%), Positives = 39/86 (45%), Gaps = 10/86 (11%) Query: 24 PAAEPP-PAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASG--- 79 PAA PP P GL P+ GAP S + G+A P+ T PAA + G Sbjct: 1198 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKG-APTTPAATPPSPKGGPA 1256 Query: 80 ---PSESPSPPAA--EELPGSHAEPP 100 P +P+PPAA L G A PP Sbjct: 1257 TPPPKGAPTPPAATPPSLKGGLATPP 1282 Score = 42.0 bits (97), Expect = 0.002 Identities = 31/85 (36%), Positives = 36/85 (42%), Gaps = 4/85 (4%) Query: 24 PAAEPP-PAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASGPSE 82 PAA PP P GL P GAP S + G+A P+ T PAA + G Sbjct: 1106 PAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKG-APTTPAATPPSPKGGLA 1164 Query: 83 SPSPPAAEELPGSHAEPPVPAQGEA 107 +P P A P A PP P G A Sbjct: 1165 TPPPKGAPTTPA--ATPPSPKGGLA 1187 Score = 38.9 bits (89), Expect = 0.019 Identities = 30/85 (35%), Positives = 35/85 (41%), Gaps = 4/85 (4%) Query: 24 PAAEPP-PAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASGPSE 82 PAA PP P G P+ GAP S + G+A P T PAA + G Sbjct: 1083 PAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLA-TPPHKGAPTTPAATPPSPKGGLA 1141 Query: 83 SPSPPAAEELPGSHAEPPVPAQGEA 107 +P P A P A PP P G A Sbjct: 1142 TPPPKGAPTTPA--ATPPSPKGGLA 1164 Score = 36.6 bits (83), Expect = 0.096 Identities = 32/104 (30%), Positives = 40/104 (38%), Gaps = 20/104 (19%) Query: 24 PAAEPPPAEG-LLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASG--- 79 PAA PP +G L P GAP A S + G A + P+ T PAA + G Sbjct: 1267 PAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKG-APTPPAATPPSPKGSPG 1325 Query: 80 ---PSESPSPPAAEE------------LPGSHAEPPVPAQGEAP 108 P +P+PPA P S P P+ E P Sbjct: 1326 TPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGP 1369 Score = 35.4 bits (80), Expect = 0.21 Identities = 32/109 (29%), Positives = 40/109 (36%), Gaps = 12/109 (11%) Query: 9 VPEAAEERAEPGQQQPAAEPP-PAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVR 67 +P + + P PAA PP P G P+ AP S + G A P+ Sbjct: 930 IPASPSPKGAP--TPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKG-AP 986 Query: 68 TEPAAEAEAASGPSESPSPPAAEELP--------GSHAEPPVPAQGEAP 108 T PAA + G +PSP A P GS A P P P Sbjct: 987 TPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTP 1035 Score = 34.7 bits (78), Expect = 0.37 Identities = 28/81 (34%), Positives = 34/81 (41%), Gaps = 5/81 (6%) Query: 24 PAAEPP-PAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASG-PS 81 PAA PP P G P+ GAP S + G A P+ T PA + G P+ Sbjct: 966 PAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKG-APTPPAVTPPSPKGSPA 1024 Query: 82 ESPSPPAAEELPGSHAEPPVP 102 +P P A P A PP P Sbjct: 1025 ATPFPKGASTPPA--ATPPSP 1043 Score = 34.7 bits (78), Expect = 0.37 Identities = 25/92 (27%), Positives = 34/92 (36%), Gaps = 5/92 (5%) Query: 17 AEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGP----ESEVRTEPAA 72 A P + + PP +G P P GT ++ GP E T PAA Sbjct: 1315 ATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAA 1374 Query: 73 EAEAASGPSES-PSPPAAEELPGSHAEPPVPA 103 GP+ + PSP +P +P PA Sbjct: 1375 TPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPA 1406 Score = 33.9 bits (76), Expect = 0.62 Identities = 28/87 (32%), Positives = 35/87 (40%), Gaps = 9/87 (10%) Query: 28 PPPAEGLLRPAGPGAPEAAGTEASSEEV-------GIAEAGPESEVRTEPAAEAEAASGP 80 P P EG PA AP + T +S ++ GI + T PAA + G Sbjct: 894 PFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGG 953 Query: 81 SESPSPPAAEELPGSHAEPPVPAQGEA 107 +PSP A P A PP P G A Sbjct: 954 PATPSPKWAPTPPA--ATPPSPKGGPA 978 Score = 33.1 bits (74), Expect = 1.1 Identities = 27/82 (32%), Positives = 32/82 (39%), Gaps = 3/82 (3%) Query: 26 AEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASGPSESPS 85 A P P P+ GAP S + G A P+ T PAA + G +PS Sbjct: 923 ATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKW-APTPPAATPPSPKGGPATPS 981 Query: 86 PPAAEELPGSHAEPPVPAQGEA 107 P A P A PP P G A Sbjct: 982 PKGAPTPPA--ATPPSPKGGPA 1001 Score = 31.6 bits (70), Expect = 3.1 Identities = 26/89 (29%), Positives = 38/89 (42%), Gaps = 15/89 (16%) Query: 19 PGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAAS 78 P ++ A P P E PA P + EA+ A + P+ E+ PA + + Sbjct: 1556 PSPKKTPAIPTPKEA---PATPSSKEASSPPAVTPSTYKGAPSPK-ELLIPPAVTSPS-- 1609 Query: 79 GPSESPSPPAAEELPGSHAEPPVPAQGEA 107 P E+P+PPA PP P +G A Sbjct: 1610 -PKEAPTPPA--------VTPPSPEKGPA 1629 Score = 30.0 bits (66), Expect = 9.0 Identities = 41/147 (27%), Positives = 50/147 (34%), Gaps = 23/147 (15%) Query: 24 PAAEPPPAEGLLRPAGPGAPEAAG-------TEASSEEVGIAEAGPESEVRTEPAAEAEA 76 PAA PP +G GP P G T S + A P+ T PAA + Sbjct: 989 PAATPPSPKG-----GPATPSPKGAPTPPAVTPPSPKGSPAATPFPKG-ASTPPAATPPS 1042 Query: 77 ASG-------PSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAG 129 G P +P+ PAA LP P P+ AP A S A G Sbjct: 1043 PKGSPAATPLPKGAPTTPAA-TLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKG 1101 Query: 130 GNEGRAAEAEPRALENGDADEPSFSDP 156 A A P + + G A P P Sbjct: 1102 APMPPA--ATPPSPKGGLATPPHKGAP 1126 >gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo sapiens] Length = 1487 Score = 45.8 bits (107), Expect = 2e-04 Identities = 46/160 (28%), Positives = 51/160 (31%), Gaps = 16/160 (10%) Query: 12 AAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPA 71 AA R GQ PA P P P PGAP A G EAGP E A Sbjct: 340 AAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKG-----------EAGPTGARGPEGA 388 Query: 72 AEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGGN 131 G SP P A PG+ P APG R + A G Sbjct: 389 QGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGP 448 Query: 132 EG-RAAEAEPRAL----ENGDADEPSFSDPEDFVDDVSEE 166 G + EP E G EP + P+ EE Sbjct: 449 LGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEE 488 Score = 40.8 bits (94), Expect = 0.005 Identities = 40/158 (25%), Positives = 53/158 (33%), Gaps = 20/158 (12%) Query: 12 AAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEA----------G 61 +A R PG++ P PA P G P A G + + + G A A G Sbjct: 814 SAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPG 873 Query: 62 PESEVRTEPAAEAEAASGPSESPSPPAAEEL---PGSHAEPPVPAQGEAPGEQARDERSD 118 P+ A A GP + P A PGS+ P P PG +D Sbjct: 874 PQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPG---PPGPSGKDGPKG 930 Query: 119 SRAQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDP 156 +R + G G A P G+ EP P Sbjct: 931 ARGDSGPPGRAGEPGLQGPAGP----PGEKGEPGDDGP 964 Score = 40.4 bits (93), Expect = 0.007 Identities = 43/145 (29%), Positives = 57/145 (39%), Gaps = 21/145 (14%) Query: 19 PGQQQPAAEP--PPAEGLLRPAGPGAPEAA----GTEASSEEVGIAEAGPESEVRTEPAA 72 PG + A P A G P GP P+ A G + + E GIA E + EP Sbjct: 416 PGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGP 475 Query: 73 EAEAASGPSESPSPPAAEELPGSHAEP----PVPAQGE--APGEQARDERSDSRAQAVSE 126 +GP +P P E G+ EP P+ GE APG + + A + Sbjct: 476 -----AGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQD---GLAGPK 527 Query: 127 DAGGNEGRAAEAEPRALENGDADEP 151 A G G + A P+ NGD P Sbjct: 528 GAPGERGPSGLAGPKG-ANGDPGRP 551 Score = 39.7 bits (91), Expect = 0.011 Identities = 38/143 (26%), Positives = 52/143 (36%), Gaps = 8/143 (5%) Query: 4 AENVAVPEAAEERAEPGQQQPAAEPPP--AEGLLRPAGPGAPEAAGTEASSEEVGIAEAG 61 A +A P+ +R + G++ P P GL P GP P AG EVG Sbjct: 757 AAGIAGPKG--DRGDVGEKGPEGAPGKDGGRGLTGPIGPPGP--AGANGEKGEVGPPGPA 812 Query: 62 PESEVRTEPAAEAEAA-SGPSESPSPPAAEELPGSHAEPPVPAQ-GEAPGEQARDERSDS 119 + R P E GP+ PP A+ PG+ E Q G+A + Sbjct: 813 GSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAP 872 Query: 120 RAQAVSEDAGGNEGRAAEAEPRA 142 Q + G R A+ P A Sbjct: 873 GPQGPTGVTGPKGARGAQGPPGA 895 Score = 38.9 bits (89), Expect = 0.019 Identities = 41/152 (26%), Positives = 54/152 (35%), Gaps = 17/152 (11%) Query: 7 VAVPEAAEERAEPGQQQPAAEP-----PPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAG 61 V +P ER PG P+ EP P A G P GP P A E G Sbjct: 983 VGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPA-------GEPG 1035 Query: 62 PESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRA 121 E + + A+G A PG+ P P G+Q +R ++ A Sbjct: 1036 REGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG--DRGEAGA 1093 Query: 122 QAVSEDAG--GNEGRAAEAEPRALENGDADEP 151 Q +G G G PR + G+A EP Sbjct: 1094 QGPMGPSGPAGARGIQGPQGPRG-DKGEAGEP 1124 Score = 38.5 bits (88), Expect = 0.025 Identities = 42/139 (30%), Positives = 51/139 (36%), Gaps = 27/139 (19%) Query: 20 GQQQPAAEPPPAEGLLRPAGP-GAPEAAGTE----ASSEEVGIAEAGPESEV-----RTE 69 G+Q P EP PA GP GAP AG E A E G+ GP E R Sbjct: 465 GEQGPKGEPGPA-------GPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGF 517 Query: 70 PAAE-------AEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQ 122 P + A GPS P A PG EP +P A G R + + + Sbjct: 518 PGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPG---ARGLTGRPGDAGPQGK 574 Query: 123 AVSEDAGGNEGRAAEAEPR 141 A G +GR P+ Sbjct: 575 VGPSGAPGEDGRPGPPGPQ 593 Score = 36.2 bits (82), Expect = 0.13 Identities = 39/142 (27%), Positives = 51/142 (35%), Gaps = 9/142 (6%) Query: 13 AEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAA 72 A + PG++ P+ P P PG P G + G +AGP+ +V A Sbjct: 524 AGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPG--DAGPQGKVGPSGAP 581 Query: 73 EAEAASGPSESPSPPAAEELPGSHAEP-PVPAQGE--APGEQARDERSDSRAQAVSEDAG 129 + GP P P A PG P P A GE GE+ R + Sbjct: 582 GEDGRPGP---PGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGET 638 Query: 130 GNEGRAAEAEPRALENGDADEP 151 G G A P A E G+ P Sbjct: 639 GAAGPPGPAGP-AGERGEQGAP 659 Score = 35.0 bits (79), Expect = 0.28 Identities = 38/143 (26%), Positives = 50/143 (34%), Gaps = 8/143 (5%) Query: 10 PEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGI-AEAGPESEVRT 68 P AA PG P P + GA +G + E G+ AGP E + Sbjct: 899 PGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGE-KG 957 Query: 69 EPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDA 128 EP + GPS + PP + L G +P Q G S + + A Sbjct: 958 EPGDD-----GPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGA 1012 Query: 129 GGNEGRAAEAEPRALENGDADEP 151 G+ G P L G A EP Sbjct: 1013 SGDRGPPGPVGPPGL-TGPAGEP 1034 Score = 34.3 bits (77), Expect = 0.48 Identities = 35/137 (25%), Positives = 49/137 (35%), Gaps = 18/137 (13%) Query: 10 PEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTE 69 P A+ +R PG P PA R PGA G + + AG + + Sbjct: 1010 PGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGA--------AGVKGDRGET 1061 Query: 70 PAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAG 129 A A A GP SP P G +GEA + + A+ + G Sbjct: 1062 GAVGAPGAPGPPGSPGPAGPTGKQGD--------RGEAGAQGPMGPSGPAGARGIQGPQG 1113 Query: 130 --GNEGRAAEAEPRALE 144 G++G A E R L+ Sbjct: 1114 PRGDKGEAGEPGERGLK 1130 Score = 33.9 bits (76), Expect = 0.62 Identities = 31/97 (31%), Positives = 35/97 (36%), Gaps = 14/97 (14%) Query: 19 PGQQQPAAEPPPA--EGLLRPAGPGAPEAAGTEASSEEVGIA----EAGPESEVRTEPAA 72 PG + EP A +GL PGAP G E G A AGP E + A Sbjct: 605 PGPKGANGEPGKAGEKGL-----PGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAP 659 Query: 73 EAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPG 109 G P PP PG VP + APG Sbjct: 660 GPSGFQGLPGPPGPPGEGGKPGDQG---VPGEAGAPG 693 Score = 33.5 bits (75), Expect = 0.81 Identities = 33/130 (25%), Positives = 43/130 (33%), Gaps = 12/130 (9%) Query: 16 RAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAE 75 R PG PA P P P PG P +G GP + + A Sbjct: 209 RGPPG---PAGAPGPQGFQGNPGEPGEPGVSGPMGPR-----GPPGPPGKPGDDGEAGKP 260 Query: 76 AASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAG--GNEG 133 +G P P A PG+ P V PG + ++ A V ++G G G Sbjct: 261 GKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDG--AKGEAGAPGVKGESGSPGENG 318 Query: 134 RAAEAEPRAL 143 PR L Sbjct: 319 SPGPMGPRGL 328 Score = 32.3 bits (72), Expect = 1.8 Identities = 47/172 (27%), Positives = 52/172 (30%), Gaps = 21/172 (12%) Query: 15 ERAEPGQQQP--AAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEA-GPESEVRTEPA 71 E+ EPG P A PP +GL G G E G GP E + A Sbjct: 955 EKGEPGDDGPSGAEGPPGPQGLAGQRG-----IVGLPGQRGERGFPGLPGPSGEPGKQGA 1009 Query: 72 AEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGGN 131 A GP PP L G EP A G RD A V D G Sbjct: 1010 PGASGDRGPPGPVGPPG---LTGPAGEPGREGSPGADGPPGRD-----GAAGVKGDRGET 1061 Query: 132 EGRAAEAEPRALENGDADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEADGI 183 A P G P + P D E G + P A GI Sbjct: 1062 GAVGAPGAP-----GPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGI 1108 Score = 31.2 bits (69), Expect = 4.0 Identities = 32/154 (20%), Positives = 50/154 (32%), Gaps = 15/154 (9%) Query: 11 EAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEP 70 + A +PG + EP + ++ P GP P+ E + G + E Sbjct: 92 DLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPR----GDRGDKGEKGAPG 147 Query: 71 AAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSE---- 126 + G +P PP PG P + A DE++ V + Sbjct: 148 PRGRDGEPGTPGNPGPPGP---PGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMG 204 Query: 127 --DAGGNEGRAAEAEPRALEN--GDADEPSFSDP 156 G G A P+ + G+ EP S P Sbjct: 205 PMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGP 238 >gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo sapiens] Length = 1418 Score = 45.8 bits (107), Expect = 2e-04 Identities = 46/160 (28%), Positives = 51/160 (31%), Gaps = 16/160 (10%) Query: 12 AAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPA 71 AA R GQ PA P P P PGAP A G EAGP E A Sbjct: 271 AAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKG-----------EAGPTGARGPEGA 319 Query: 72 AEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGGN 131 G SP P A PG+ P APG R + A G Sbjct: 320 QGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGP 379 Query: 132 EG-RAAEAEPRAL----ENGDADEPSFSDPEDFVDDVSEE 166 G + EP E G EP + P+ EE Sbjct: 380 LGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEE 419 Score = 40.8 bits (94), Expect = 0.005 Identities = 40/158 (25%), Positives = 53/158 (33%), Gaps = 20/158 (12%) Query: 12 AAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEA----------G 61 +A R PG++ P PA P G P A G + + + G A A G Sbjct: 745 SAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPG 804 Query: 62 PESEVRTEPAAEAEAASGPSESPSPPAAEEL---PGSHAEPPVPAQGEAPGEQARDERSD 118 P+ A A GP + P A PGS+ P P PG +D Sbjct: 805 PQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPG---PPGPSGKDGPKG 861 Query: 119 SRAQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDP 156 +R + G G A P G+ EP P Sbjct: 862 ARGDSGPPGRAGEPGLQGPAGP----PGEKGEPGDDGP 895 Score = 40.4 bits (93), Expect = 0.007 Identities = 43/145 (29%), Positives = 57/145 (39%), Gaps = 21/145 (14%) Query: 19 PGQQQPAAEP--PPAEGLLRPAGPGAPEAA----GTEASSEEVGIAEAGPESEVRTEPAA 72 PG + A P A G P GP P+ A G + + E GIA E + EP Sbjct: 347 PGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGP 406 Query: 73 EAEAASGPSESPSPPAAEELPGSHAEP----PVPAQGE--APGEQARDERSDSRAQAVSE 126 +GP +P P E G+ EP P+ GE APG + + A + Sbjct: 407 -----AGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQD---GLAGPK 458 Query: 127 DAGGNEGRAAEAEPRALENGDADEP 151 A G G + A P+ NGD P Sbjct: 459 GAPGERGPSGLAGPKG-ANGDPGRP 482 Score = 39.7 bits (91), Expect = 0.011 Identities = 38/143 (26%), Positives = 52/143 (36%), Gaps = 8/143 (5%) Query: 4 AENVAVPEAAEERAEPGQQQPAAEPPP--AEGLLRPAGPGAPEAAGTEASSEEVGIAEAG 61 A +A P+ +R + G++ P P GL P GP P AG EVG Sbjct: 688 AAGIAGPKG--DRGDVGEKGPEGAPGKDGGRGLTGPIGPPGP--AGANGEKGEVGPPGPA 743 Query: 62 PESEVRTEPAAEAEAA-SGPSESPSPPAAEELPGSHAEPPVPAQ-GEAPGEQARDERSDS 119 + R P E GP+ PP A+ PG+ E Q G+A + Sbjct: 744 GSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAP 803 Query: 120 RAQAVSEDAGGNEGRAAEAEPRA 142 Q + G R A+ P A Sbjct: 804 GPQGPTGVTGPKGARGAQGPPGA 826 Score = 38.9 bits (89), Expect = 0.019 Identities = 41/152 (26%), Positives = 54/152 (35%), Gaps = 17/152 (11%) Query: 7 VAVPEAAEERAEPGQQQPAAEP-----PPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAG 61 V +P ER PG P+ EP P A G P GP P A E G Sbjct: 914 VGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPA-------GEPG 966 Query: 62 PESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRA 121 E + + A+G A PG+ P P G+Q +R ++ A Sbjct: 967 REGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG--DRGEAGA 1024 Query: 122 QAVSEDAG--GNEGRAAEAEPRALENGDADEP 151 Q +G G G PR + G+A EP Sbjct: 1025 QGPMGPSGPAGARGIQGPQGPRG-DKGEAGEP 1055 Score = 38.5 bits (88), Expect = 0.025 Identities = 42/139 (30%), Positives = 51/139 (36%), Gaps = 27/139 (19%) Query: 20 GQQQPAAEPPPAEGLLRPAGP-GAPEAAGTE----ASSEEVGIAEAGPESEV-----RTE 69 G+Q P EP PA GP GAP AG E A E G+ GP E R Sbjct: 396 GEQGPKGEPGPA-------GPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGF 448 Query: 70 PAAE-------AEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQ 122 P + A GPS P A PG EP +P A G R + + + Sbjct: 449 PGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPG---ARGLTGRPGDAGPQGK 505 Query: 123 AVSEDAGGNEGRAAEAEPR 141 A G +GR P+ Sbjct: 506 VGPSGAPGEDGRPGPPGPQ 524 Score = 36.2 bits (82), Expect = 0.13 Identities = 39/142 (27%), Positives = 51/142 (35%), Gaps = 9/142 (6%) Query: 13 AEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAA 72 A + PG++ P+ P P PG P G + G +AGP+ +V A Sbjct: 455 AGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPG--DAGPQGKVGPSGAP 512 Query: 73 EAEAASGPSESPSPPAAEELPGSHAEP-PVPAQGE--APGEQARDERSDSRAQAVSEDAG 129 + GP P P A PG P P A GE GE+ R + Sbjct: 513 GEDGRPGP---PGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGET 569 Query: 130 GNEGRAAEAEPRALENGDADEP 151 G G A P A E G+ P Sbjct: 570 GAAGPPGPAGP-AGERGEQGAP 590 Score = 35.0 bits (79), Expect = 0.28 Identities = 38/143 (26%), Positives = 50/143 (34%), Gaps = 8/143 (5%) Query: 10 PEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGI-AEAGPESEVRT 68 P AA PG P P + GA +G + E G+ AGP E + Sbjct: 830 PGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGE-KG 888 Query: 69 EPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDA 128 EP + GPS + PP + L G +P Q G S + + A Sbjct: 889 EPGDD-----GPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGA 943 Query: 129 GGNEGRAAEAEPRALENGDADEP 151 G+ G P L G A EP Sbjct: 944 SGDRGPPGPVGPPGL-TGPAGEP 965 Score = 34.3 bits (77), Expect = 0.48 Identities = 35/137 (25%), Positives = 49/137 (35%), Gaps = 18/137 (13%) Query: 10 PEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTE 69 P A+ +R PG P PA R PGA G + + AG + + Sbjct: 941 PGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGA--------AGVKGDRGET 992 Query: 70 PAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAG 129 A A A GP SP P G +GEA + + A+ + G Sbjct: 993 GAVGAPGAPGPPGSPGPAGPTGKQGD--------RGEAGAQGPMGPSGPAGARGIQGPQG 1044 Query: 130 --GNEGRAAEAEPRALE 144 G++G A E R L+ Sbjct: 1045 PRGDKGEAGEPGERGLK 1061 Score = 33.9 bits (76), Expect = 0.62 Identities = 31/97 (31%), Positives = 35/97 (36%), Gaps = 14/97 (14%) Query: 19 PGQQQPAAEPPPA--EGLLRPAGPGAPEAAGTEASSEEVGIA----EAGPESEVRTEPAA 72 PG + EP A +GL PGAP G E G A AGP E + A Sbjct: 536 PGPKGANGEPGKAGEKGL-----PGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAP 590 Query: 73 EAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPG 109 G P PP PG VP + APG Sbjct: 591 GPSGFQGLPGPPGPPGEGGKPGDQG---VPGEAGAPG 624 Score = 33.5 bits (75), Expect = 0.81 Identities = 33/130 (25%), Positives = 43/130 (33%), Gaps = 12/130 (9%) Query: 16 RAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAE 75 R PG PA P P P PG P +G GP + + A Sbjct: 140 RGPPG---PAGAPGPQGFQGNPGEPGEPGVSGPMGPR-----GPPGPPGKPGDDGEAGKP 191 Query: 76 AASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAG--GNEG 133 +G P P A PG+ P V PG + ++ A V ++G G G Sbjct: 192 GKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDG--AKGEAGAPGVKGESGSPGENG 249 Query: 134 RAAEAEPRAL 143 PR L Sbjct: 250 SPGPMGPRGL 259 Score = 32.3 bits (72), Expect = 1.8 Identities = 47/172 (27%), Positives = 52/172 (30%), Gaps = 21/172 (12%) Query: 15 ERAEPGQQQP--AAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEA-GPESEVRTEPA 71 E+ EPG P A PP +GL G G E G GP E + A Sbjct: 886 EKGEPGDDGPSGAEGPPGPQGLAGQRG-----IVGLPGQRGERGFPGLPGPSGEPGKQGA 940 Query: 72 AEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGGN 131 A GP PP L G EP A G RD A V D G Sbjct: 941 PGASGDRGPPGPVGPPG---LTGPAGEPGREGSPGADGPPGRD-----GAAGVKGDRGET 992 Query: 132 EGRAAEAEPRALENGDADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEADGI 183 A P G P + P D E G + P A GI Sbjct: 993 GAVGAPGAP-----GPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGI 1039 Score = 30.4 bits (67), Expect = 6.9 Identities = 31/147 (21%), Positives = 48/147 (32%), Gaps = 15/147 (10%) Query: 18 EPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAA 77 +PG + EP + ++ P GP P+ E + G + E + Sbjct: 30 QPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPR----GDRGDKGEKGAPGPRGRDGE 85 Query: 78 SGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSE------DAGGN 131 G +P PP PG P + A DE++ V + G Sbjct: 86 PGTPGNPGPPGP---PGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGP 142 Query: 132 EGRAAEAEPRALEN--GDADEPSFSDP 156 G A P+ + G+ EP S P Sbjct: 143 PGPAGAPGPQGFQGNPGEPGEPGVSGP 169 >gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] Length = 1020 Score = 45.8 bits (107), Expect = 2e-04 Identities = 51/174 (29%), Positives = 72/174 (41%), Gaps = 16/174 (9%) Query: 7 VAVPEAAEERA-EPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEA-GPE- 63 V PE A+ A E + P A+ P E PA +PE A + A E AEA PE Sbjct: 544 VKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEK 603 Query: 64 --SEVRTEPAAEAEA-------ASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARD 114 S V+ E + AEA A P+E SP A+ A+ P A+ E Sbjct: 604 AKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSP 663 Query: 115 ERSDS--RAQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFVDDVSEE 166 E++ S +A+A S + + +A P ++ +E PE V EE Sbjct: 664 EKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEA--KSPEKAKSPVKEE 715 Score = 39.7 bits (91), Expect = 0.011 Identities = 43/180 (23%), Positives = 72/180 (40%), Gaps = 13/180 (7%) Query: 1 MQDAENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEA 60 ++ E + V E +E+ ++Q E E + A E G E E AE Sbjct: 438 VKSEEKIKVVEKSEKETVIVEEQ-TEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEG 496 Query: 61 GPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSR 120 G E E ++ PA EA AS E+ SP E + A+ P + ++P E E++ S Sbjct: 497 G-EEETKSPPAEEA--ASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSP 553 Query: 121 AQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEA 180 A+ E + E ++ E +A P+ + ++EE P++A Sbjct: 554 AK---------EEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKA 604 Score = 36.6 bits (83), Expect = 0.096 Identities = 42/163 (25%), Positives = 63/163 (38%), Gaps = 26/163 (15%) Query: 5 ENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPES 64 E V PE A+ + + P E P E + P E +EV + E ++ Sbjct: 791 EEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKE--------EEKPQEVKVKEPPKKA 842 Query: 65 EVRTEPAA-------EAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERS 117 E PA +++ P + P EE E P ++ EA E+A D++ Sbjct: 843 EEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKK 902 Query: 118 ----DSRAQA---VSEDAGGNE-GRAAEAEPRALENGDADEPS 152 + A A V EDA E A+ EP ++ A EPS Sbjct: 903 VPTPEKEAPAKVEVKEDAKPKEKTEVAKKEP---DDAKAKEPS 942 Score = 36.2 bits (82), Expect = 0.13 Identities = 43/135 (31%), Positives = 55/135 (40%), Gaps = 19/135 (14%) Query: 4 AENVAVPEA-AEERAEPGQQQPA-AEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEA- 60 AE A PE A+ + + PA A+ P E PA +PE A + A E EA Sbjct: 506 AEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAK 565 Query: 61 GPESEVRTEPAA----------EAEAASGPSESPSPPAAE----ELPGSHAEPPVPAQGE 106 PE E PA E A P+E+ SP A+ E S AE P + E Sbjct: 566 SPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEE 625 Query: 107 A--PGEQARDERSDS 119 A P E E++ S Sbjct: 626 AKSPAEVKSPEKAKS 640 Score = 34.7 bits (78), Expect = 0.37 Identities = 32/166 (19%), Positives = 59/166 (35%), Gaps = 11/166 (6%) Query: 8 AVPEAAEERAEPGQQQPAAEPP-PAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEV 66 A P+ E++ ++ P E P P + P+ + EA EE + P E Sbjct: 849 ATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEK 908 Query: 67 RTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARD----------ER 116 E + + P E E EP PA+ + + +D E+ Sbjct: 909 EAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEK 968 Query: 117 SDSRAQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFVDD 162 + A+A +D ++ + +A ++ D+ PE +D Sbjct: 969 PKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATED 1014 >gi|118601081 heterogeneous nuclear ribonucleoprotein U-like 2 [Homo sapiens] Length = 747 Score = 45.8 bits (107), Expect = 2e-04 Identities = 38/126 (30%), Positives = 54/126 (42%), Gaps = 10/126 (7%) Query: 11 EAAEERAEPGQQQPAAEPPPAEGLLRPA--GPGAPEAAGTEASSEEVGIAEAGPESEVRT 68 E EE E + EPPPA+ L + A P PEAA EA++E SE Sbjct: 80 EEEEEDEEALLEDEDEEPPPAQALGQAAQPPPEPPEAAAMEAAAEP-------DASEKPA 132 Query: 69 EPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDA 128 E A + +G E E+ P + P E PG++A +E+ D + S+ A Sbjct: 133 EATAGSGGVNGGEEQGLGKREEDEPEERSGDETPG-SEVPGDKAAEEQGDDQDSEKSKPA 191 Query: 129 GGNEGR 134 G + R Sbjct: 192 GSDGER 197 Score = 45.4 bits (106), Expect = 2e-04 Identities = 43/162 (26%), Positives = 59/162 (36%), Gaps = 31/162 (19%) Query: 44 EAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASGPS--------------------ES 83 EA E +E G AGP + EP A + GP E Sbjct: 35 EALDAEMLEDEAGGGGAGPGGACKAEPRPVAASGGGPGGDEEEDEEEEEEDEEALLEDED 94 Query: 84 PSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRAL 143 PP A+ L + PP P + A A + S+ A+A + G N G E + L Sbjct: 95 EEPPPAQALGQAAQPPPEPPEAAAMEAAAEPDASEKPAEATAGSGGVNGG-----EEQGL 149 Query: 144 ENGDADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEADGIDS 185 + DEP E D+ E+ GD K ++ D DS Sbjct: 150 GKREEDEPE----ERSGDETPGSEVPGD--KAAEEQGDDQDS 185 Score = 40.8 bits (94), Expect = 0.005 Identities = 38/135 (28%), Positives = 51/135 (37%), Gaps = 10/135 (7%) Query: 2 QDAENVAVPEAAEERAEPGQ-----QQPAAEPPPAEGLLRPAGPGAPE--AAGTEASSEE 54 ++ + A+ E +E P Q QP EPP A + A P A E A T S Sbjct: 82 EEEDEEALLEDEDEEPPPAQALGQAAQPPPEPPEAAAMEAAAEPDASEKPAEATAGSGGV 141 Query: 55 VGIAEAGPESEVRTEPAAEAEAASGPSESPSPPAAEEL---PGSHAEPPVPAQGEAPGEQ 111 G E G EP + + SE P AAEE S P + GE G + Sbjct: 142 NGGEEQGLGKREEDEPEERSGDETPGSEVPGDKAAEEQGDDQDSEKSKPAGSDGERRGVK 201 Query: 112 ARDERSDSRAQAVSE 126 + + D +A E Sbjct: 202 RQRDEKDEHGRAYYE 216 Score = 33.9 bits (76), Expect = 0.62 Identities = 35/137 (25%), Positives = 46/137 (33%), Gaps = 33/137 (24%) Query: 10 PEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAG---PESEV 66 PE E A +P A PAE G E G E+ +G P SEV Sbjct: 111 PEPPEAAAMEAAAEPDASEKPAEATAGSGGVNGGEEQGLGKREEDEPEERSGDETPGSEV 170 Query: 67 RTEPAAEAEAASGPSESPSPPAA-------------------------EELPGSHAEPPV 101 + AAE + SE P + EE S ++ P+ Sbjct: 171 PGDKAAEEQGDDQDSEKSKPAGSDGERRGVKRQRDEKDEHGRAYYEFREEAYHSRSKSPL 230 Query: 102 PAQGEAPGEQARDERSD 118 P P E+A+DE D Sbjct: 231 P-----PEEEAKDEEED 242 >gi|226053185 paternally expressed 3 isoform 3 [Homo sapiens] Length = 1464 Score = 45.4 bits (106), Expect = 2e-04 Identities = 44/127 (34%), Positives = 56/127 (44%), Gaps = 16/127 (12%) Query: 44 EAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPA 103 + EA+ EV AE PE E EP EA +G +E P AAE + G +P Sbjct: 1264 QGLNVEAAEPEVEAAE--PEVEA-AEPEVEAAEPNGEAEGPDGEAAEPI-GEAGQP--NG 1317 Query: 104 QGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDADEP---SFSDPEDFV 160 + E P A DE + + E A EG+A E E GDADEP DPE+ Sbjct: 1318 EAEQPNGDA-DEPDGAGIEDPEERAEEPEGKAEEPE------GDADEPDGVGIEDPEEGE 1370 Query: 161 DDVSEEE 167 D + E Sbjct: 1371 DQEIQVE 1377 Score = 35.8 bits (81), Expect = 0.16 Identities = 37/131 (28%), Positives = 53/131 (40%), Gaps = 11/131 (8%) Query: 63 ESEVRTEPAAEAEAASGPSESPS--PPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSR 120 E E E AA A AA+ E+ P + G + E P + EA + + Sbjct: 1232 EEEEEDEAAAAAAAAAQEVEANVHVPQVVLRIQGLNVEAAEP-EVEAAEPEVEAAEPEVE 1290 Query: 121 AQAVSEDAGGNEGRAAEAEPRALE--------NGDADEPSFSDPEDFVDDVSEEELLGDV 172 A + +A G +G AAE A + NGDADEP + ED + E E + Sbjct: 1291 AAEPNGEAEGPDGEAAEPIGEAGQPNGEAEQPNGDADEPDGAGIEDPEERAEEPEGKAEE 1350 Query: 173 LKDRPQEADGI 183 + E DG+ Sbjct: 1351 PEGDADEPDGV 1361 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.133 0.405 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 34,886,810 Number of Sequences: 37866 Number of extensions: 1796742 Number of successful extensions: 18165 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 201 Number of HSP's successfully gapped in prelim test: 1263 Number of HSP's that attempted gapping in prelim test: 12378 Number of HSP's gapped (non-prelim): 5549 length of query: 814 length of database: 18,247,518 effective HSP length: 111 effective length of query: 703 effective length of database: 14,044,392 effective search space: 9873207576 effective search space used: 9873207576 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.