BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|33188461 GATA binding protein 4 [Homo sapiens] (442 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|33188461 GATA binding protein 4 [Homo sapiens] 901 0.0 gi|40288197 GATA binding protein 6 [Homo sapiens] 362 e-100 gi|17998698 GATA binding protein 5 [Homo sapiens] 327 2e-89 gi|224611699 GATA binding protein 2 isoform 1 [Homo sapiens] 239 3e-63 gi|20070352 GATA binding protein 2 isoform 1 [Homo sapiens] 239 3e-63 gi|50541959 GATA binding protein 3 isoform 1 [Homo sapiens] 215 6e-56 gi|4503929 GATA binding protein 3 isoform 2 [Homo sapiens] 214 1e-55 gi|224611701 GATA binding protein 2 isoform 2 [Homo sapiens] 208 7e-54 gi|4503925 GATA binding protein 1 [Homo sapiens] 202 5e-52 gi|90652851 zinc finger transcription factor TRPS1 [Homo sapiens] 80 5e-15 gi|73476377 LBXCOR1 homolog [Homo sapiens] 60 3e-09 gi|122692281 hypothetical protein LOC645369 [Homo sapiens] 56 6e-08 gi|126352608 elastin isoform e precursor [Homo sapiens] 55 1e-07 gi|126352322 elastin isoform c precursor [Homo sapiens] 55 1e-07 gi|126352700 elastin isoform b precursor [Homo sapiens] 55 1e-07 gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens] 54 2e-07 gi|153792074 proline rich 12 [Homo sapiens] 54 2e-07 gi|110347449 POU domain, class 4, transcription factor 1 [Homo s... 53 5e-07 gi|33946327 nucleoporin 214kDa [Homo sapiens] 52 8e-07 gi|195972866 keratin 10 [Homo sapiens] 52 1e-06 gi|109255251 loricrin [Homo sapiens] 52 1e-06 gi|210147522 zinc finger, SWIM-type containing 6 [Homo sapiens] 52 1e-06 gi|119395750 keratin 1 [Homo sapiens] 51 2e-06 gi|55956899 keratin 9 [Homo sapiens] 50 3e-06 gi|239757043 PREDICTED: functional smad suppressing element 18 [... 50 3e-06 gi|239751555 PREDICTED: functional smad suppressing element 18 [... 50 3e-06 gi|239746067 PREDICTED: functional smad suppressing element 18 [... 50 3e-06 gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 50 5e-06 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 49 1e-05 gi|119395716 forkhead box C1 [Homo sapiens] 49 1e-05 >gi|33188461 GATA binding protein 4 [Homo sapiens] Length = 442 Score = 901 bits (2329), Expect = 0.0 Identities = 442/442 (100%), Positives = 442/442 (100%) Query: 1 MYQSLAMAANHGPPPGAYEAGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAG 60 MYQSLAMAANHGPPPGAYEAGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAG Sbjct: 1 MYQSLAMAANHGPPPGAYEAGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAG 60 Query: 61 SASGGASGGSSGGAASGAGPGTQQGSPGWSQAGADGAAYTPPPVSPRFSFPGTTGSLAAA 120 SASGGASGGSSGGAASGAGPGTQQGSPGWSQAGADGAAYTPPPVSPRFSFPGTTGSLAAA Sbjct: 61 SASGGASGGSSGGAASGAGPGTQQGSPGWSQAGADGAAYTPPPVSPRFSFPGTTGSLAAA 120 Query: 121 AAAAAAREAAAYSSGGGAAGAGLAGREQYGRAGFAGSYSSPYPAYMADVGASWAAAAAAS 180 AAAAAAREAAAYSSGGGAAGAGLAGREQYGRAGFAGSYSSPYPAYMADVGASWAAAAAAS Sbjct: 121 AAAAAAREAAAYSSGGGAAGAGLAGREQYGRAGFAGSYSSPYPAYMADVGASWAAAAAAS 180 Query: 181 AGPFDSPVLHSLPGRANPAARHPNLDMFDDFSEGRECVNCGAMSTPLWRRDGTGHYLCNA 240 AGPFDSPVLHSLPGRANPAARHPNLDMFDDFSEGRECVNCGAMSTPLWRRDGTGHYLCNA Sbjct: 181 AGPFDSPVLHSLPGRANPAARHPNLDMFDDFSEGRECVNCGAMSTPLWRRDGTGHYLCNA 240 Query: 241 CGLYHKMNGINRPLIKPQRRLSASRRVGLSCANCQTTTTTLWRRNAEGEPVCNACGLYMK 300 CGLYHKMNGINRPLIKPQRRLSASRRVGLSCANCQTTTTTLWRRNAEGEPVCNACGLYMK Sbjct: 241 CGLYHKMNGINRPLIKPQRRLSASRRVGLSCANCQTTTTTLWRRNAEGEPVCNACGLYMK 300 Query: 301 LHGVPRPLAMRKEGIQTRKRKPKNLNKSKTPAAPSGSESLPPASGASSNSSNATTSSSEE 360 LHGVPRPLAMRKEGIQTRKRKPKNLNKSKTPAAPSGSESLPPASGASSNSSNATTSSSEE Sbjct: 301 LHGVPRPLAMRKEGIQTRKRKPKNLNKSKTPAAPSGSESLPPASGASSNSSNATTSSSEE 360 Query: 361 MRPIKTEPGLSSHYGHSSSVSQTFSVSAMSGHGPSIHPVLSALKLSPQGYASPVSQSPQT 420 MRPIKTEPGLSSHYGHSSSVSQTFSVSAMSGHGPSIHPVLSALKLSPQGYASPVSQSPQT Sbjct: 361 MRPIKTEPGLSSHYGHSSSVSQTFSVSAMSGHGPSIHPVLSALKLSPQGYASPVSQSPQT 420 Query: 421 SSKQDSWNSLVLADSHGDIITA 442 SSKQDSWNSLVLADSHGDIITA Sbjct: 421 SSKQDSWNSLVLADSHGDIITA 442 >gi|40288197 GATA binding protein 6 [Homo sapiens] Length = 595 Score = 362 bits (929), Expect = e-100 Identities = 228/476 (47%), Positives = 277/476 (58%), Gaps = 70/476 (14%) Query: 1 MYQSLAMAANHGPPPGAYEAGGPGAFMHGAGAA-------SSPVYVPTPRVPSSVLGLSY 53 MYQ+LA ++ GP AY+ G PG F+H A AA SSPVYVPT RV S + GL Y Sbjct: 147 MYQTLAALSSQGP--AAYD-GAPGGFVHSAAAAAAAAAAASSPVYVPTTRVGSMLPGLPY 203 Query: 54 -LQGGGAGSAS--GGASGGSSGGAASGAGP--GTQQGSPGWSQAGADGAAYTPPPVSPRF 108 LQG G+G A+ GGA AS P G+ G+ G AG GA VS RF Sbjct: 204 HLQGSGSGPANHAGGAGAHPGWPQASADSPPYGSGGGAAGGGAAGPGGAGSAAAHVSARF 263 Query: 109 SFPGTTGSLAAAAA-----AAAAREAAAYSSGGGAAGAGLAGRE-QYGRAGFA----GSY 158 + + AA AAA A SGGG++ A + GRE QY A G+Y Sbjct: 264 PYSPSPPMANGAAREPGGYAAAGSGGAGGVSGGGSSLAAMGGREPQYSSLSAARPLNGTY 323 Query: 159 S----------SPYPAYM-ADVGASWAAAAAASAGPFDSPVLHSLPGRAN---PAARHPN 204 SPY Y+ A + +W A GPF++PVLHSL RA P R P+ Sbjct: 324 HHHHHHHHHHPSPYSPYVGAPLTPAWPA------GPFETPVLHSLQSRAGAPLPVPRGPS 377 Query: 205 LDMFDDFSEGRECVNCGAMSTPLWRRDGTGHYLCNACGLYHKMNGINRPLIKPQRRLSAS 264 D+ +D SE RECVNCG++ TPLWRRDGTGHYLCNACGLY KMNG++RPLIKPQ+R+ +S Sbjct: 378 ADLLEDLSESRECVNCGSIQTPLWRRDGTGHYLCNACGLYSKMNGLSRPLIKPQKRVPSS 437 Query: 265 RRVGLSCANCQTTTTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMRKEGIQTRKRKPKN 324 RR+GLSCANC TTTTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAM+KEGIQTRKRKPKN Sbjct: 438 RRLGLSCANCHTTTTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMKKEGIQTRKRKPKN 497 Query: 325 LNKSKTPAAPSGSESLPPASGASSNSSNATTSSSEEMRPIKTEPGLSSHYGHSSSVSQTF 384 +NKSKT + S + + SSNS + + ++S +P + G Sbjct: 498 INKSKTCSGNSNNSIPMTPTSTSSNSDDCSKNTSPTTQPTASGAG--------------- 542 Query: 385 SVSAMSGHGPSIHPVLSALKLSPQ-------GYASPVSQSPQTSSKQDSWNSLVLA 433 M+G G S +P S LK S Q ASP + +S + DSW +L LA Sbjct: 543 -APVMTGAGESTNPENSELKYSGQDGLYIGVSLASPAEVT--SSVRPDSWCALALA 595 >gi|17998698 GATA binding protein 5 [Homo sapiens] Length = 397 Score = 327 bits (837), Expect = 2e-89 Identities = 205/446 (45%), Positives = 256/446 (57%), Gaps = 62/446 (13%) Query: 1 MYQSLAMAANHGPPPGAYEAGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAG 60 MYQSLA+AA+ P AY G+F+H GA S P++VP RVPS LSYL G Sbjct: 1 MYQSLALAAS--PRQAAY--ADSGSFLHAPGAGS-PMFVPPARVPSM---LSYLSG---- 48 Query: 61 SASGGASGGSSGGAASGAGPGTQQGSPGWSQ-AGADGAAYTP-PPVSPRFSFPGTTGSLA 118 P PGW+Q A AD +A+ P P P PG T Sbjct: 49 -------------CEPSPQPPELAARPGWAQTATADSSAFGPGSPHPPAAHPPGATAFPF 95 Query: 119 AAAAAAAAREAAAYSSGGGAAGAGLAGREQY----GRAGFAGSYSSPYPAYMA-DVGASW 173 A + + +A G A L REQ+ GR SYS+ YPAY++ DV SW Sbjct: 96 AHSPSGPGSGGSAGGRDGSAYQGALLPREQFAAPLGRP-VGTSYSATYPAYVSPDVAQSW 154 Query: 174 AAAAAASAGPFDSPVLHSLPGRANPAARHPNLDMFDDF-SEGRECVNCGAMSTPLWRRDG 232 +AGPFD VLH LPGR D ++F EGRECVNCGA+STPLWRRDG Sbjct: 155 ------TAGPFDGSVLHGLPGRRPTFVS----DFLEEFPGEGRECVNCGALSTPLWRRDG 204 Query: 233 TGHYLCNACGLYHKMNGINRPLIKPQRRLSASRRVGLSCANCQTTTTTLWRRNAEGEPVC 292 TGHYLCNACGLYHKMNG+NRPL++PQ+RLS+SRR GL C NC TT TTLWRRN+EGEPVC Sbjct: 205 TGHYLCNACGLYHKMNGVNRPLVRPQKRLSSSRRAGLCCTNCHTTNTTLWRRNSEGEPVC 264 Query: 293 NACGLYMKLHGVPRPLAMRKEGIQTRKRKPKNLNKSKTPAAPSGSESLPPASGASSNSSN 352 NACGLYMKLHGVPRPLAM+KE IQTRKRKPK + K++ + + + S P++ AS++SS Sbjct: 265 NACGLYMKLHGVPRPLAMKKESIQTRKRKPKTIAKARGSSGSTRNASASPSAVASTDSSA 324 Query: 353 ATTSSSEEMRPIKTEPGLSSHYGHSSSVSQTFSVSAMSGHGPSIHPVLSALKLSPQGYAS 412 AT+ K +P L+S S++ A S+ P K P+ +A Sbjct: 325 ATS---------KAKPSLASPVCPGPSMAP----QASGQEDDSLAPGHLEFKFEPEDFAF 371 Query: 413 P-VSQSPQT----SSKQDSWNSLVLA 433 P + SPQ + +Q++W +L LA Sbjct: 372 PSTAPSPQAGLRGALRQEAWCALALA 397 >gi|224611699 GATA binding protein 2 isoform 1 [Homo sapiens] Length = 480 Score = 239 bits (611), Expect = 3e-63 Identities = 156/373 (41%), Positives = 185/373 (49%), Gaps = 38/373 (10%) Query: 21 GGPGAFMHGAGAASSPVYVP----TPRVPSSVLGLSYLQGGGAGSASGGASGGSSGGAAS 76 GG A A +P V TP PS+ G GG S GA GGS GG+ S Sbjct: 100 GGKAALSAAAAHHHNPWTVSPFSKTPLHPSAAGG-----PGGPLSVYPGAGGGSGGGSGS 154 Query: 77 GAGPGTQQGSPGWSQAGADGAAYTPPPVSPRFSFPGTTGSLAAAAAAAAAREAAAYSSGG 136 T P + +G+ + P P P TTG+ + A+++A A G Sbjct: 155 SVASLT----PTAAHSGSHLFGFPPTPPKEVSPDPSTTGAASPASSSAGGSAARGEDKDG 210 Query: 137 GAAGAGLAGREQYG-----RAGFAGSYSSP--------YPAYMADVGASWAAAAAASAGP 183 L + R G A + P YP+Y+ +++ G Sbjct: 211 VKYQVSLTESMKMESGSPLRPGLATMGTQPATHHPIPTYPSYVPAAAHDYSSGLFHPGGF 270 Query: 184 FDSPVLHSLPGRANPAARHPNLDMFDDFSEGRECVNCGAMSTPLWRRDGTGHYLCNACGL 243 P P + + A SEGRECVNCGA +TPLWRRDGTGHYLCNACGL Sbjct: 271 LGGPASSFTPKQRSKAR---------SCSEGRECVNCGATATPLWRRDGTGHYLCNACGL 321 Query: 244 YHKMNGINRPLIKPQRRLSASRRVGLSCANCQTTTTTLWRRNAEGEPVCNACGLYMKLHG 303 YHKMNG NRPLIKP+RRLSA+RR G CANCQTTTTTLWRRNA G+PVCNACGLY KLH Sbjct: 322 YHKMNGQNRPLIKPKRRLSAARRAGTCCANCQTTTTTLWRRNANGDPVCNACGLYYKLHN 381 Query: 304 VPRPLAMRKEGIQTRKRKPKNLNKSKTPAAPSGSESLPPASGASSNSSNATTSSSEEMRP 363 V RPL M+KEGIQTR RK N +K A E SS S A + M P Sbjct: 382 VNRPLTMKKEGIQTRNRKMSNKSKKSKKGAECFEELSKCMQEKSSPFSAAALAG--HMAP 439 Query: 364 IKTEPGLSSHYGH 376 + P SH GH Sbjct: 440 VGHLPPF-SHSGH 451 >gi|20070352 GATA binding protein 2 isoform 1 [Homo sapiens] Length = 480 Score = 239 bits (611), Expect = 3e-63 Identities = 156/373 (41%), Positives = 185/373 (49%), Gaps = 38/373 (10%) Query: 21 GGPGAFMHGAGAASSPVYVP----TPRVPSSVLGLSYLQGGGAGSASGGASGGSSGGAAS 76 GG A A +P V TP PS+ G GG S GA GGS GG+ S Sbjct: 100 GGKAALSAAAAHHHNPWTVSPFSKTPLHPSAAGG-----PGGPLSVYPGAGGGSGGGSGS 154 Query: 77 GAGPGTQQGSPGWSQAGADGAAYTPPPVSPRFSFPGTTGSLAAAAAAAAAREAAAYSSGG 136 T P + +G+ + P P P TTG+ + A+++A A G Sbjct: 155 SVASLT----PTAAHSGSHLFGFPPTPPKEVSPDPSTTGAASPASSSAGGSAARGEDKDG 210 Query: 137 GAAGAGLAGREQYG-----RAGFAGSYSSP--------YPAYMADVGASWAAAAAASAGP 183 L + R G A + P YP+Y+ +++ G Sbjct: 211 VKYQVSLTESMKMESGSPLRPGLATMGTQPATHHPIPTYPSYVPAAAHDYSSGLFHPGGF 270 Query: 184 FDSPVLHSLPGRANPAARHPNLDMFDDFSEGRECVNCGAMSTPLWRRDGTGHYLCNACGL 243 P P + + A SEGRECVNCGA +TPLWRRDGTGHYLCNACGL Sbjct: 271 LGGPASSFTPKQRSKAR---------SCSEGRECVNCGATATPLWRRDGTGHYLCNACGL 321 Query: 244 YHKMNGINRPLIKPQRRLSASRRVGLSCANCQTTTTTLWRRNAEGEPVCNACGLYMKLHG 303 YHKMNG NRPLIKP+RRLSA+RR G CANCQTTTTTLWRRNA G+PVCNACGLY KLH Sbjct: 322 YHKMNGQNRPLIKPKRRLSAARRAGTCCANCQTTTTTLWRRNANGDPVCNACGLYYKLHN 381 Query: 304 VPRPLAMRKEGIQTRKRKPKNLNKSKTPAAPSGSESLPPASGASSNSSNATTSSSEEMRP 363 V RPL M+KEGIQTR RK N +K A E SS S A + M P Sbjct: 382 VNRPLTMKKEGIQTRNRKMSNKSKKSKKGAECFEELSKCMQEKSSPFSAAALAG--HMAP 439 Query: 364 IKTEPGLSSHYGH 376 + P SH GH Sbjct: 440 VGHLPPF-SHSGH 451 >gi|50541959 GATA binding protein 3 isoform 1 [Homo sapiens] Length = 444 Score = 215 bits (548), Expect = 6e-56 Identities = 145/365 (39%), Positives = 179/365 (49%), Gaps = 39/365 (10%) Query: 51 LSYLQGGGAGSASGGASGGS----SGGAASGAGPGTQQGSPGWSQAGADGAAYTP----- 101 L +L GG A + AS + S + PG P S + G +P Sbjct: 94 LPWLDGGKALGSHHTASPWNLSPFSKTSIHHGSPGPLSVYPPASSSSLSGGHASPHLFTF 153 Query: 102 PPVSPRFSFPGTTGSLAAAAAAAAA--REAAAYSSGGGAAGAGLAGREQYGRAGFAGSYS 159 PP P+ P + S +A +A +E Y + + + G+ S Sbjct: 154 PPTPPKDVSPDPSLSTPGSAGSARQDEKECLKYQVPLPDSMKLESSHSRGSMTALGGASS 213 Query: 160 SP------YPAYMADVGASWAAAAAASAGPFDSPVLHSLPGRANPAARHPNLDMFDDFSE 213 S YP Y+ + + ++ G SP R P AR +E Sbjct: 214 STHHPITTYPPYVPEYSSGLFPPSSLLGG---SPTGFGCKSR--PKARSS--------TE 260 Query: 214 GRECVNCGAMSTPLWRRDGTGHYLCNACGLYHKMNGINRPLIKPQRRLSASRRVGLSCAN 273 GRECVNCGA STPLWRRDGTGHYLCNACGLYHKMNG NRPLIKP+RRLSA+RR G SCAN Sbjct: 261 GRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTSCAN 320 Query: 274 CQTTTTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMRKEGIQTRKRKPKNLNKSKTPAA 333 CQTTTTTLWRRNA G+PVCNACGLY KLH + RPL M+KEGIQTR RK + +K K Sbjct: 321 CQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKMSSKSK-KCKKV 379 Query: 334 PSGSESLPPASGASSNSSNATTSSSEEMRPIKTEPGLSSHYGHSSSVSQTFSVSAMSGHG 393 E P S + + + SS + P SH H + + G Sbjct: 380 HDSLEDFPKNSSFNPAALSRHMSSLSHISPF-------SHSSHMLTTPTPMHPPSSLSFG 432 Query: 394 PSIHP 398 P HP Sbjct: 433 PH-HP 436 >gi|4503929 GATA binding protein 3 isoform 2 [Homo sapiens] Length = 443 Score = 214 bits (545), Expect = 1e-55 Identities = 145/365 (39%), Positives = 178/365 (48%), Gaps = 40/365 (10%) Query: 51 LSYLQGGGAGSASGGASGGS----SGGAASGAGPGTQQGSPGWSQAGADGAAYTP----- 101 L +L GG A + AS + S + PG P S + G +P Sbjct: 94 LPWLDGGKALGSHHTASPWNLSPFSKTSIHHGSPGPLSVYPPASSSSLSGGHASPHLFTF 153 Query: 102 PPVSPRFSFPGTTGSLAAAAAAAAA--REAAAYSSGGGAAGAGLAGREQYGRAGFAGSYS 159 PP P+ P + S +A +A +E Y + + + G+ S Sbjct: 154 PPTPPKDVSPDPSLSTPGSAGSARQDEKECLKYQVPLPDSMKLESSHSRGSMTALGGASS 213 Query: 160 SP------YPAYMADVGASWAAAAAASAGPFDSPVLHSLPGRANPAARHPNLDMFDDFSE 213 S YP Y+ + + ++ G SP R P AR S Sbjct: 214 STHHPITTYPPYVPEYSSGLFPPSSLLGG---SPTGFGCKSR--PKARS---------ST 259 Query: 214 GRECVNCGAMSTPLWRRDGTGHYLCNACGLYHKMNGINRPLIKPQRRLSASRRVGLSCAN 273 GRECVNCGA STPLWRRDGTGHYLCNACGLYHKMNG NRPLIKP+RRLSA+RR G SCAN Sbjct: 260 GRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTSCAN 319 Query: 274 CQTTTTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMRKEGIQTRKRKPKNLNKSKTPAA 333 CQTTTTTLWRRNA G+PVCNACGLY KLH + RPL M+KEGIQTR RK + +K K Sbjct: 320 CQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKMSSKSK-KCKKV 378 Query: 334 PSGSESLPPASGASSNSSNATTSSSEEMRPIKTEPGLSSHYGHSSSVSQTFSVSAMSGHG 393 E P S + + + SS + P SH H + + G Sbjct: 379 HDSLEDFPKNSSFNPAALSRHMSSLSHISPF-------SHSSHMLTTPTPMHPPSSLSFG 431 Query: 394 PSIHP 398 P HP Sbjct: 432 PH-HP 435 >gi|224611701 GATA binding protein 2 isoform 2 [Homo sapiens] Length = 466 Score = 208 bits (530), Expect = 7e-54 Identities = 146/373 (39%), Positives = 174/373 (46%), Gaps = 52/373 (13%) Query: 21 GGPGAFMHGAGAASSPVYVP----TPRVPSSVLGLSYLQGGGAGSASGGASGGSSGGAAS 76 GG A A +P V TP PS+ G GG S GA GGS GG+ S Sbjct: 100 GGKAALSAAAAHHHNPWTVSPFSKTPLHPSAAGG-----PGGPLSVYPGAGGGSGGGSGS 154 Query: 77 GAGPGTQQGSPGWSQAGADGAAYTPPPVSPRFSFPGTTGSLAAAAAAAAAREAAAYSSGG 136 T P + +G+ + P P P TTG+ + A+++A A G Sbjct: 155 SVASLT----PTAAHSGSHLFGFPPTPPKEVSPDPSTTGAASPASSSAGGSAARGEDKDG 210 Query: 137 GAAGAGLAGREQYG-----RAGFAGSYSSP--------YPAYMADVGASWAAAAAASAGP 183 L + R G A + P YP+Y+ +++ G Sbjct: 211 VKYQVSLTESMKMESGSPLRPGLATMGTQPATHHPIPTYPSYVPAAAHDYSSGLFHPGGF 270 Query: 184 FDSPVLHSLPGRANPAARHPNLDMFDDFSEGRECVNCGAMSTPLWRRDGTGHYLCNACGL 243 P P + + A SEGRECVNCGA +TPLWRRDGTGHYLCNACGL Sbjct: 271 LGGPASSFTPKQRSKAR---------SCSEGRECVNCGATATPLWRRDGTGHYLCNACGL 321 Query: 244 YHKMNGINRPLIKPQRRLSASRRVGLSCANCQTTTTTLWRRNAEGEPVCNACGLYMKLHG 303 YHKMNG NRPLIKP+RRL TTTTTLWRRNA G+PVCNACGLY KLH Sbjct: 322 YHKMNGQNRPLIKPKRRL--------------TTTTTLWRRNANGDPVCNACGLYYKLHN 367 Query: 304 VPRPLAMRKEGIQTRKRKPKNLNKSKTPAAPSGSESLPPASGASSNSSNATTSSSEEMRP 363 V RPL M+KEGIQTR RK N +K A E SS S A + M P Sbjct: 368 VNRPLTMKKEGIQTRNRKMSNKSKKSKKGAECFEELSKCMQEKSSPFSAAALAG--HMAP 425 Query: 364 IKTEPGLSSHYGH 376 + P SH GH Sbjct: 426 VGHLPPF-SHSGH 437 >gi|4503925 GATA binding protein 1 [Homo sapiens] Length = 413 Score = 202 bits (514), Expect = 5e-52 Identities = 110/217 (50%), Positives = 128/217 (58%), Gaps = 19/217 (8%) Query: 213 EGRECVNCGAMSTPLWRRDGTGHYLCNACGLYHKMNGINRPLIKPQRRLSASRRVGLSCA 272 E RECVNCGA +TPLWRRD TGHYLCNACGLYHKMNG NRPLI+P++RL S+R G C Sbjct: 200 EARECVNCGATATPLWRRDRTGHYLCNACGLYHKMNGQNRPLIRPKKRLIVSKRAGTQCT 259 Query: 273 NCQTTTTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMRKEGIQTRKRKPKNLNKSK--- 329 NCQTTTTTLWRRNA G+PVCNACGLY KLH V RPL MRK+GIQTR RK K K Sbjct: 260 NCQTTTTTLWRRNASGDPVCNACGLYYKLHQVNRPLTMRKDGIQTRNRKASGKGKKKRGS 319 Query: 330 ----TPAAPSGSESLPPASGASSNSSNATTSSSEEMRPIKTEPGLSSHYGHSSSVSQTFS 385 T AA + +G S + + +S + P PG + Y Q Sbjct: 320 SLGGTGAAEGPAGGFMVVAGGSGSGNCGEVASGLTLGP----PGTAHLY-------QGLG 368 Query: 386 VSAMSGHGPSIHPVLSALKLSPQGYASPVSQSPQTSS 422 +SG + P L SP G + P P T+S Sbjct: 369 PVVLSGPVSHLMPFPGPLLGSPTG-SFPTGPMPPTTS 404 >gi|90652851 zinc finger transcription factor TRPS1 [Homo sapiens] Length = 1294 Score = 79.7 bits (195), Expect = 5e-15 Identities = 63/193 (32%), Positives = 84/193 (43%), Gaps = 17/193 (8%) Query: 248 NGINRPLIKPQRRLSASRRVGLSCANCQTTTTTLWRRNAEGEPVCNACGLYMKLHGVPRP 307 +G N+ + Q L R G+ CANC TT T+LWR+NA G VCNACGLY KLH PRP Sbjct: 886 SGENKSKDESQSLLRRRRGSGVFCANCLTTKTSLWRKNANGGYVCNACGLYQKLHSTPRP 945 Query: 308 LAMRKEG-------IQTRKR-KPKNLNKSKTPAAPSGS-ESLPPASGASSNSSNATTSSS 358 L + K+ +TRKR P+ L + GS E S S + T S Sbjct: 946 LNIIKQNNGEQIIRRRTRKRLNPEALQAEQLNKQQRGSNEEQVNGSPLERRSEDHLTESH 1005 Query: 359 EEMRPIKTEPGLSSHYGHSS-----SVSQTFSVSAMSGHGPSIHPVLSALKLSPQGYASP 413 + P+ P LS + S S Q VS + P+ +K + P Sbjct: 1006 QREIPL---PSLSKYEAQGSLTKSHSAQQPVLVSQTLDIHKRMQPLHIQIKSPQESTGDP 1062 Query: 414 VSQSPQTSSKQDS 426 + S + K S Sbjct: 1063 GNSSSVSEGKGSS 1075 Score = 52.4 bits (124), Expect = 8e-07 Identities = 20/38 (52%), Positives = 25/38 (65%) Query: 217 CVNCGAMSTPLWRRDGTGHYLCNACGLYHKMNGINRPL 254 C NC T LWR++ G Y+CNACGLY K++ RPL Sbjct: 909 CANCLTTKTSLWRKNANGGYVCNACGLYQKLHSTPRPL 946 >gi|73476377 LBXCOR1 homolog [Homo sapiens] Length = 921 Score = 60.5 bits (145), Expect = 3e-09 Identities = 78/265 (29%), Positives = 90/265 (33%), Gaps = 90/265 (33%) Query: 12 GPPP-----------GAYEAGGPGAFMHGAGAASSPVY------------VPTPRVP--- 45 GPPP GA GPG GAG S PV +P P P Sbjct: 294 GPPPPHPQRGLGLATGASGPAGPGGPGGGAGVRSYPVIPVPSKGFGLLQKLPPPLFPHPY 353 Query: 46 -------------SSVLGLSYLQGG-GAGSASGGA-SGGSSGGAAS-----GAGPGTQQG 85 VLG +GG G GS GGA +GG +GG + GAG G G Sbjct: 354 GFPTAFGLCPKKDDPVLGAGEPKGGPGTGSGGGGAGTGGGAGGPGASHLPPGAGAGPGGG 413 Query: 86 SPGWSQ-----------AGADGAAYTPPPVSPRF----------SFPGTTGSLAAAAAAA 124 + W A AA T P P F S+P A AAA Sbjct: 414 AMFWGHQPSGAAKDAAAVAAAAAAATVYPTFPMFWPAAGSLPVPSYPAAQSQAKAVAAAV 473 Query: 125 AAREAAAYSSGGGAAGAGLAGREQYGRAGFAGSYSSPYPAYMADVGASWAAAAAASAGPF 184 AA AAA ++ G A L G E PA + +GA +A S GP Sbjct: 474 AAAAAAAAAAAGSGAPEPLDGAE---------------PAKESGLGAEERCPSALSRGPL 518 Query: 185 DS--------PVLHSLPGRANPAAR 201 D P L LP P AR Sbjct: 519 DEDGTDEALPPPLAPLPPPPPPPAR 543 Score = 39.7 bits (91), Expect = 0.006 Identities = 60/214 (28%), Positives = 69/214 (32%), Gaps = 49/214 (22%) Query: 12 GPPP------GAYEAGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAGSASGG 65 GPPP G EA GP P P P GL G + GG Sbjct: 275 GPPPHKSLRCGEDEAAGP----------------PGPPPPHPQRGLGLATGASGPAGPGG 318 Query: 66 ASGGSSGGAASGAGPGTQQGSPGWSQAGADGAAYTPPPVSPR-FSFPGTTGSLA----AA 120 G GAG + P S+ G PPP+ P + FP G Sbjct: 319 PGG--------GAGVRSYPVIPVPSK-GFGLLQKLPPPLFPHPYGFPTAFGLCPKKDDPV 369 Query: 121 AAAAAAREAAAYSSGGGAAGAG-------------LAGREQYGRAGFAGSYSSPYPAYMA 167 A + SGGG AG G AG G A F G S A Sbjct: 370 LGAGEPKGGPGTGSGGGGAGTGGGAGGPGASHLPPGAGAGPGGGAMFWGHQPSGAAKDAA 429 Query: 168 DVGASWAAAAAASAGPFDSPVLHSLPGRANPAAR 201 V A+ AAA P P SLP + PAA+ Sbjct: 430 AVAAAAAAATVYPTFPMFWPAAGSLPVPSYPAAQ 463 Score = 31.2 bits (69), Expect = 2.0 Identities = 42/150 (28%), Positives = 53/150 (35%), Gaps = 20/150 (13%) Query: 13 PPPGAYEAGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAGSASGGASGGSSG 72 PPP A + AF PV T + L S + GAG A G G SG Sbjct: 538 PPPPARKGSYVSAFR--------PVVKDTESIAK--LYGSAREAYGAGPARGPGPGAGSG 587 Query: 73 GAASGAGPGTQQGSPGWSQAGADGAAYTPPPVSPRFS-FPGTTGSLAAAAAAAAAREAAA 131 G S +GS ++ A D P V + FP A E +A Sbjct: 588 GYVS--PDFLSEGSSSYNSASPDVDTADEPEVDVESNRFPDDED-------AQEETEPSA 638 Query: 132 YSSGGGAAGAGLAGREQYGRAGFAGSYSSP 161 S+GGG G G +G G +SP Sbjct: 639 PSAGGGPDGEQPTGPPSATSSGADGPANSP 668 Score = 30.8 bits (68), Expect = 2.6 Identities = 54/187 (28%), Positives = 66/187 (35%), Gaps = 23/187 (12%) Query: 12 GPPPGAYEAG--GPGAFMHGAGAASSPVY-VPTPRVPSSVLGLSYLQGGGAGSASGGASG 68 GP PGA G P G+ + +S V T P + + S Sbjct: 579 GPGPGAGSGGYVSPDFLSEGSSSYNSASPDVDTADEPEVDVESNRFPDDEDAQEETEPSA 638 Query: 69 GSSGGAASGAGPGTQQGSPGWSQAGADGAAYTPPPVSP---RFSFPGTTGSLA---AAAA 122 S+GG G P G P + +GADG A +P SP R P G A AA Sbjct: 639 PSAGGGPDGEQP---TGPPSATSSGADGPANSPDGGSPRPRRRLGPPPAGRPAFGDLAAE 695 Query: 123 AAAAREAAAYSSGGGAAGAGLAGREQYGRAGFAGSYSSPYPA-YMADVGASWAAAAAASA 181 R + SGGG G RE G G P PA A +AA + Sbjct: 696 DLVRRPERSPPSGGG----GYELREPCGPLG------GPAPAKVFAPERDEHVKSAAVAL 745 Query: 182 GPFDSPV 188 GP S V Sbjct: 746 GPAASYV 752 >gi|122692281 hypothetical protein LOC645369 [Homo sapiens] Length = 621 Score = 56.2 bits (134), Expect = 6e-08 Identities = 102/415 (24%), Positives = 147/415 (35%), Gaps = 51/415 (12%) Query: 20 AGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAGSASGGASG-GSSGGAASGA 78 A A + ++S+P P +P + LSY+Q G GG G G + GAA+ Sbjct: 221 AAAAAAAAAASSSSSAPAAAPPGAIPLNGF-LSYVQSRGLELKPGGCGGSGDAFGAAAML 279 Query: 79 GPGTQQGSPGWSQAGADGAAYTPPPVSPRFSFPGTTGSLAAAAAAAAAREAAAYSSGGGA 138 G+ P G A +PP ++ P SLA A + Y G Sbjct: 280 AKGSWPPHPAAPSGGRPRGAASPPDLASSPRCPREPPSLAEAVYSV-------YRERSGV 332 Query: 139 AGAGLAGREQYGRAGFAGSYSSPYPAYMADVGASWAAAAAASAGPFDSPVLHSLPGRANP 198 AG+ A A A S SSP P + SW + AS+ F L + Sbjct: 333 AGSRRAAAATAAAA--ASSCSSPAPCSPPE---SWGRQSTASS--FVDSSLSAFALLPLQ 385 Query: 199 AARHPNLDMFDDFSEGRECV------NCGAMSTPLWRRDGTGHYLCNACGLYHKMNGINR 252 R D +EG C G+ P D + + N G M G R Sbjct: 386 GGRDRGGD-----AEGASCSWQRPPGERGSQEIPRGELDLS---MTNLRGAEGSMRGARR 437 Query: 253 PLIKPQRRLSASRRVGLSCANCQTTT-TTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMR 311 +P+ ++A G +T L RR+ G P A P P Sbjct: 438 EPEEPEGAVAARAARGQGGRLPRTGRYAALRRRSTSGLPDYRA---------PPSPEPPP 488 Query: 312 KEGIQTRKRKPKNLNKSKTPAAPSGSESLPPASGASSNSSNATTSSSEEMRPIKTEPGLS 371 G P L K+ +P+ P E PP S +S + SSS + E G S Sbjct: 489 SPGSADPDSSP--LAKAASPSPPLRLEGSPPTRRDSGSSQSDDPSSSNKGYTPLREAGTS 546 Query: 372 SHYGHSSSVSQTFSVSAMSGHGPSIHPVLSALKLSPQGYAS--PVSQSPQTSSKQ 424 + + QT + + PVL A + SP+G + P ++ PQ +Q Sbjct: 547 TESVLDAVAGQTRDSAVAA-------PVLGAEQSSPEGASQEPPTAEQPQPVQRQ 594 Score = 28.9 bits (63), Expect = 9.8 Identities = 31/93 (33%), Positives = 38/93 (40%), Gaps = 9/93 (9%) Query: 117 LAAAAAAAAAREAAAYSSGGGAAGAGLAGREQYGRAGFAGSYSSP----YPAYMADVGAS 172 LAAAAAAAAA A++ SS AA G GF S P G + Sbjct: 218 LAAAAAAAAAAAASSSSSAPAAAPPGAIPLN-----GFLSYVQSRGLELKPGGCGGSGDA 272 Query: 173 WAAAAAASAGPFDSPVLHSLPGRANPAARHPNL 205 + AAA + G + GR AA P+L Sbjct: 273 FGAAAMLAKGSWPPHPAAPSGGRPRGAASPPDL 305 >gi|126352608 elastin isoform e precursor [Homo sapiens] Length = 705 Score = 55.5 bits (132), Expect = 1e-07 Identities = 61/194 (31%), Positives = 78/194 (40%), Gaps = 24/194 (12%) Query: 14 PPGAYEAGGPGAFMHGAGAASSPVYVP---TPRVPSSVLGLSYLQGGG---AGSASGGAS 67 P A A A GAGAA V P VP ++ G+ + G G A +A+ A+ Sbjct: 252 PQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAA 311 Query: 68 GGSSGGAASG---AGPGTQQGSPGWSQAGADGAAYTPP--PVSPRFSFPGTT--GSLAAA 120 + GAA+G GPG G G AG G PV P PG G ++ Sbjct: 312 KAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIPGAAVPGVVSPE 371 Query: 121 AAAAAAREAAAYSSGGGAAGAGLAGREQYGRAGFAGSYSSPYPAYMADVGASWAAAAAAS 180 AAA AA +AA Y G G G+ G YG G G +P + VG A Sbjct: 372 AAAKAAAKAAKY---GARPGVGVGGIPTYG-VGAGG-----FPGFGVGVGGIPGVAGVPG 422 Query: 181 AGPFDSPVLHSLPG 194 G P + +PG Sbjct: 423 VG--GVPGVGGVPG 434 Score = 46.2 bits (108), Expect = 6e-05 Identities = 71/252 (28%), Positives = 87/252 (34%), Gaps = 57/252 (22%) Query: 2 YQSLAMAANHGPPPGAYEAG-GPGAFMHGAGAASSPVYVP---TPRV-PSSVL------G 50 Y++ A G PG G GA + GA P VP P V P VL G Sbjct: 103 YKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPG 162 Query: 51 LSYLQGGGAGSAS-------GGASGGSSG-GAASGAGPGTQQGSP--------------- 87 + L G G+ GGA G G G G PG G P Sbjct: 163 VGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYT 222 Query: 88 ------GWSQAGADGAAYTPPPVSPRFSFPGTTGSLAAAAAAAAAREAAAYSSGG----- 136 G+ G GAA + +P TG AAAAAAA+ AA + +G Sbjct: 223 TGKLPYGYGPGGVAGAA-------GKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLP 275 Query: 137 GAAGAGLAGREQY-----GRAGFAGSYSSPYPAYMADVGASWAAAAAASAGPFDSPVLHS 191 G GAG+ G G AG ++ A A AAA GP P + Sbjct: 276 GVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVG 335 Query: 192 LPGRANPAARHP 203 +PG P P Sbjct: 336 VPGAGVPGVGVP 347 Score = 44.3 bits (103), Expect = 2e-04 Identities = 59/206 (28%), Positives = 72/206 (34%), Gaps = 37/206 (17%) Query: 13 PPPGAYEAGGPGAFMHGAGAASSPVYVP--TPRVPSSVLGLSYLQG--------GGAGSA 62 P G AG PG G P+ P P++P GL Y G GG A Sbjct: 180 PGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGY-GLPYTTGKLPYGYGPGGVAGA 238 Query: 63 SG------GASGGSSGGAASGA------GPGTQQGSPGWSQAGADGAAYTPPPVSPRFSF 110 +G G G AA+ A G G PG AG G P + Sbjct: 239 AGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV 298 Query: 111 PGTTGSLAAAAAAAAAR--EAAAYSSGGGAAGAGLAGREQYGRAGF------------AG 156 + AAAAAA AA+ AA GG G G+ G G G AG Sbjct: 299 GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAG 358 Query: 157 SYSSPYPAYMADVGASWAAAAAASAG 182 + P ++ A+ AAA AA G Sbjct: 359 IPGAAVPGVVSPEAAAKAAAKAAKYG 384 Score = 38.5 bits (88), Expect = 0.012 Identities = 36/117 (30%), Positives = 41/117 (35%), Gaps = 16/117 (13%) Query: 42 PRVPSSVLGLSYLQGGGAGSASGGASGGSSGGAASGAGPGTQQGSPGWSQAGADGAAYTP 101 PR +L LS L G G GG GG PG G+ G G G P Sbjct: 9 PRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFY---PGAGLGALGGGALGPGGKPLKP 65 Query: 102 PP-------------VSPRFSFPGTTGSLAAAAAAAAAREAAAYSSGGGAAGAGLAG 145 P P +FPG A AAAA + A A + GG G G G Sbjct: 66 VPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLG 122 Score = 37.4 bits (85), Expect = 0.027 Identities = 53/177 (29%), Positives = 61/177 (34%), Gaps = 19/177 (10%) Query: 20 AGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAGSASGGASGGSSGGAASGAG 79 A G GA + G G V VP V + V GL G A GA + A Sbjct: 524 AAGLGAGIPGLGVG---VGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAV 580 Query: 80 PGTQQGSPGWSQAGADGAAYTPPPVSPRFSFPGTTGSLAAAAAAAAAREAAAYSSGGGAA 139 PG G G G P + AAAAA AAA+ AA GAA Sbjct: 581 PGVLGGLGALGGVGIPGGVVGAGPAA------------AAAAAKAAAK--AAQFGLVGAA 626 Query: 140 GAGLAGREQYGRAGFAGSYSSP--YPAYMADVGASWAAAAAASAGPFDSPVLHSLPG 194 G G G G G G P A A GA+ AG F + + PG Sbjct: 627 GLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPG 683 Score = 35.4 bits (80), Expect = 0.10 Identities = 63/214 (29%), Positives = 78/214 (36%), Gaps = 24/214 (11%) Query: 3 QSLAMAANHGPPPGA-------YEAGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQ 55 ++ A AA +G PG Y G G G G P P V V G+ + Sbjct: 375 KAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGV-GGVPGVGGVP 433 Query: 56 GGG------AGSASGGASGGSSGGAASGAGPGTQQG---SPGWSQAGADGAAYTPPPVSP 106 G G A +A+ A G G G G G +PG A G A V+P Sbjct: 434 GVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVA-PGVGVAP 492 Query: 107 RFSF-PGT-TGSLAAAAAAAAAREAAAYSSGGGAAGAGLAG-REQYGRAGF---AGSYSS 160 PG G +AAAA +AA A A GAG+ G G G AG Sbjct: 493 GVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGL 552 Query: 161 PYPAYMADVGASWAAAAAASAGPFDSPVLHSLPG 194 A + GA A AAA A + + V L G Sbjct: 553 GVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGG 586 >gi|126352322 elastin isoform c precursor [Homo sapiens] Length = 692 Score = 55.5 bits (132), Expect = 1e-07 Identities = 61/194 (31%), Positives = 78/194 (40%), Gaps = 24/194 (12%) Query: 14 PPGAYEAGGPGAFMHGAGAASSPVYVP---TPRVPSSVLGLSYLQGGG---AGSASGGAS 67 P A A A GAGAA V P VP ++ G+ + G G A +A+ A+ Sbjct: 257 PQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAA 316 Query: 68 GGSSGGAASG---AGPGTQQGSPGWSQAGADGAAYTPP--PVSPRFSFPGTT--GSLAAA 120 + GAA+G GPG G G AG G PV P PG G ++ Sbjct: 317 KAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIPGAAVPGVVSPE 376 Query: 121 AAAAAAREAAAYSSGGGAAGAGLAGREQYGRAGFAGSYSSPYPAYMADVGASWAAAAAAS 180 AAA AA +AA Y G G G+ G YG G G +P + VG A Sbjct: 377 AAAKAAAKAAKY---GARPGVGVGGIPTYG-VGAGG-----FPGFGVGVGGIPGVAGVPG 427 Query: 181 AGPFDSPVLHSLPG 194 G P + +PG Sbjct: 428 VG--GVPGVGGVPG 439 Score = 46.2 bits (108), Expect = 6e-05 Identities = 72/257 (28%), Positives = 88/257 (34%), Gaps = 62/257 (24%) Query: 2 YQSLAMAANHGPPPGAYEAGG------PGAFMHGAGAASSPVYVP---TPRV-PSSVL-- 49 Y++ A G PG G PGA + GA P VP P V P VL Sbjct: 103 YKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPG 162 Query: 50 ----GLSYLQGGGAGSAS-------GGASGGSSG-GAASGAGPGTQQGSP---------- 87 G+ L G G+ GGA G G G G PG G P Sbjct: 163 ARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGY 222 Query: 88 -----------GWSQAGADGAAYTPPPVSPRFSFPGTTGSLAAAAAAAAAREAAAYSSGG 136 G+ G GAA + +P TG AAAAAAA+ AA + +G Sbjct: 223 GLPYTTGKLPYGYGPGGVAGAA-------GKAGYPTGTGVGPQAAAAAAAKAAAKFGAGA 275 Query: 137 -----GAAGAGLAGREQY-----GRAGFAGSYSSPYPAYMADVGASWAAAAAASAGPFDS 186 G GAG+ G G AG ++ A A AAA GP Sbjct: 276 AGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG 335 Query: 187 PVLHSLPGRANPAARHP 203 P + +PG P P Sbjct: 336 PGVVGVPGAGVPGVGVP 352 Score = 44.3 bits (103), Expect = 2e-04 Identities = 59/206 (28%), Positives = 72/206 (34%), Gaps = 37/206 (17%) Query: 13 PPPGAYEAGGPGAFMHGAGAASSPVYVP--TPRVPSSVLGLSYLQG--------GGAGSA 62 P G AG PG G P+ P P++P GL Y G GG A Sbjct: 185 PGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGY-GLPYTTGKLPYGYGPGGVAGA 243 Query: 63 SG------GASGGSSGGAASGA------GPGTQQGSPGWSQAGADGAAYTPPPVSPRFSF 110 +G G G AA+ A G G PG AG G P + Sbjct: 244 AGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV 303 Query: 111 PGTTGSLAAAAAAAAAR--EAAAYSSGGGAAGAGLAGREQYGRAGF------------AG 156 + AAAAAA AA+ AA GG G G+ G G G AG Sbjct: 304 GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAG 363 Query: 157 SYSSPYPAYMADVGASWAAAAAASAG 182 + P ++ A+ AAA AA G Sbjct: 364 IPGAAVPGVVSPEAAAKAAAKAAKYG 389 Score = 40.0 bits (92), Expect = 0.004 Identities = 52/186 (27%), Positives = 63/186 (33%), Gaps = 30/186 (16%) Query: 42 PRVPSSVLGLSYLQGGGAGSASGGASGGSSGGAASGAGPGTQQGSPGWSQAGADGAAYTP 101 PR +L LS L G G GG GG PG G+ G G G P Sbjct: 9 PRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFY---PGAGLGALGGGALGPGGKPLKP 65 Query: 102 PP-------------VSPRFSFPGTTGSLAAAAAAAAAREAAAYSSGGGAAGAGLAGREQ 148 P P +FPG A AAAA + A AGAGL G Sbjct: 66 VPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAA--------KAGAGLGGVPG 117 Query: 149 YGRAGFAGSYSSPYPAYMADVGASWAAAAAASAGPFDSPVLHSLPGRANPAARHPNLDMF 208 G G + + S P A + GA G P ++ PG P AR P + + Sbjct: 118 VGGLGVSAAPSVP-GAVVPQPGAGVKPGKVPGVG---LPGVY--PGGVLPGARFPGVGVL 171 Query: 209 DDFSEG 214 G Sbjct: 172 PGVPTG 177 Score = 37.0 bits (84), Expect = 0.036 Identities = 57/197 (28%), Positives = 68/197 (34%), Gaps = 24/197 (12%) Query: 5 LAMAANHGPPPGAYEAGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAGSASG 64 + +A G PG A G G G G + ++ L G GAG Sbjct: 481 VGLAPGVGVAPGVGVAPGVGV-APGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGL 539 Query: 65 GASGGSSG-GAASGA-GPGTQQGSPGWSQAGADGAAYTPPPVSPRFSFPGTTGSLAA--- 119 G G G G +G G G G PG+ GA + PG G L A Sbjct: 540 GVGVGVPGLGVGAGVPGLGVGAGVPGFG--AVPGALAAAKAAKYGAAVPGVLGGLGALGG 597 Query: 120 ------------AAAAAAAREAAAYSSGG--GAAGAGLAGREQYGRAGFAGSYSSPYPAY 165 AAAAAAA+ AA + G GAAG G G G G G P A Sbjct: 598 VGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAA- 656 Query: 166 MADVGASWAAAAAASAG 182 A A + AA G Sbjct: 657 -AAKAAKYGVAARPGFG 672 Score = 29.6 bits (65), Expect = 5.7 Identities = 46/162 (28%), Positives = 53/162 (32%), Gaps = 35/162 (21%) Query: 20 AGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAGSASGGASGGSSGGAASGAG 79 A G GA + G G V VP V + V GL G A GA + A Sbjct: 529 AAGLGAGIPGLGVG---VGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAV 585 Query: 80 PGTQQGSPGWSQAGADGAAYTPPPVSPRFSFPGTTGSLAAAAAAAAAREA------AAYS 133 PG G G G P + AAAAA AAA+ A AA Sbjct: 586 PGVLGGLGALGGVGIPGGVVGAGPAA------------AAAAAKAAAKAAQFGLVGAAGL 633 Query: 134 SGGGAAGAGLAG--------------REQYGRAGFAGSYSSP 161 G G G G+ G +YG A G SP Sbjct: 634 GGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSP 675 >gi|126352700 elastin isoform b precursor [Homo sapiens] Length = 677 Score = 55.5 bits (132), Expect = 1e-07 Identities = 61/194 (31%), Positives = 78/194 (40%), Gaps = 24/194 (12%) Query: 14 PPGAYEAGGPGAFMHGAGAASSPVYVP---TPRVPSSVLGLSYLQGGG---AGSASGGAS 67 P A A A GAGAA V P VP ++ G+ + G G A +A+ A+ Sbjct: 242 PQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAA 301 Query: 68 GGSSGGAASG---AGPGTQQGSPGWSQAGADGAAYTPP--PVSPRFSFPGTT--GSLAAA 120 + GAA+G GPG G G AG G PV P PG G ++ Sbjct: 302 KAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIPGAAVPGVVSPE 361 Query: 121 AAAAAAREAAAYSSGGGAAGAGLAGREQYGRAGFAGSYSSPYPAYMADVGASWAAAAAAS 180 AAA AA +AA Y G G G+ G YG G G +P + VG A Sbjct: 362 AAAKAAAKAAKY---GARPGVGVGGIPTYG-VGAGG-----FPGFGVGVGGIPGVAGVPG 412 Query: 181 AGPFDSPVLHSLPG 194 G P + +PG Sbjct: 413 VG--GVPGVGGVPG 424 Score = 46.2 bits (108), Expect = 6e-05 Identities = 71/252 (28%), Positives = 87/252 (34%), Gaps = 57/252 (22%) Query: 2 YQSLAMAANHGPPPGAYEAG-GPGAFMHGAGAASSPVYVP---TPRV-PSSVL------G 50 Y++ A G PG G GA + GA P VP P V P VL G Sbjct: 93 YKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPG 152 Query: 51 LSYLQGGGAGSAS-------GGASGGSSG-GAASGAGPGTQQGSP--------------- 87 + L G G+ GGA G G G G PG G P Sbjct: 153 VGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYT 212 Query: 88 ------GWSQAGADGAAYTPPPVSPRFSFPGTTGSLAAAAAAAAAREAAAYSSGG----- 136 G+ G GAA + +P TG AAAAAAA+ AA + +G Sbjct: 213 TGKLPYGYGPGGVAGAA-------GKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLP 265 Query: 137 GAAGAGLAGREQY-----GRAGFAGSYSSPYPAYMADVGASWAAAAAASAGPFDSPVLHS 191 G GAG+ G G AG ++ A A AAA GP P + Sbjct: 266 GVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVG 325 Query: 192 LPGRANPAARHP 203 +PG P P Sbjct: 326 VPGAGVPGVGVP 337 Score = 44.3 bits (103), Expect = 2e-04 Identities = 59/206 (28%), Positives = 72/206 (34%), Gaps = 37/206 (17%) Query: 13 PPPGAYEAGGPGAFMHGAGAASSPVYVP--TPRVPSSVLGLSYLQG--------GGAGSA 62 P G AG PG G P+ P P++P GL Y G GG A Sbjct: 170 PGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGY-GLPYTTGKLPYGYGPGGVAGA 228 Query: 63 SG------GASGGSSGGAASGA------GPGTQQGSPGWSQAGADGAAYTPPPVSPRFSF 110 +G G G AA+ A G G PG AG G P + Sbjct: 229 AGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV 288 Query: 111 PGTTGSLAAAAAAAAAR--EAAAYSSGGGAAGAGLAGREQYGRAGF------------AG 156 + AAAAAA AA+ AA GG G G+ G G G AG Sbjct: 289 GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAG 348 Query: 157 SYSSPYPAYMADVGASWAAAAAASAG 182 + P ++ A+ AAA AA G Sbjct: 349 IPGAAVPGVVSPEAAAKAAAKAAKYG 374 Score = 37.0 bits (84), Expect = 0.036 Identities = 37/108 (34%), Positives = 43/108 (39%), Gaps = 8/108 (7%) Query: 42 PRVPSSVLGLSYLQGGGAGSASGGASGGSSGGAASGA-GPGTQQGSP---GWSQAGADGA 97 PR +L LS L G G GG GG A GPG + P G + AG Sbjct: 9 PRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPALGPGGKPLKPVPGGLAGAGLGAG 68 Query: 98 AYTPPPVSPRFSFPGTTGSLAAAAAAAAAREAAAYSSGGGAAGAGLAG 145 P V+ FPG A AAAA + A A + GG G G G Sbjct: 69 LGAFPAVT----FPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLG 112 Score = 37.0 bits (84), Expect = 0.036 Identities = 57/197 (28%), Positives = 68/197 (34%), Gaps = 24/197 (12%) Query: 5 LAMAANHGPPPGAYEAGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAGSASG 64 + +A G PG A G G G G + ++ L G GAG Sbjct: 466 VGLAPGVGVAPGVGVAPGVGV-APGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGL 524 Query: 65 GASGGSSG-GAASGA-GPGTQQGSPGWSQAGADGAAYTPPPVSPRFSFPGTTGSLAA--- 119 G G G G +G G G G PG+ GA + PG G L A Sbjct: 525 GVGVGVPGLGVGAGVPGLGVGAGVPGFG--AVPGALAAAKAAKYGAAVPGVLGGLGALGG 582 Query: 120 ------------AAAAAAAREAAAYSSGG--GAAGAGLAGREQYGRAGFAGSYSSPYPAY 165 AAAAAAA+ AA + G GAAG G G G G G P A Sbjct: 583 VGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAA- 641 Query: 166 MADVGASWAAAAAASAG 182 A A + AA G Sbjct: 642 -AAKAAKYGVAARPGFG 657 Score = 29.6 bits (65), Expect = 5.7 Identities = 46/162 (28%), Positives = 53/162 (32%), Gaps = 35/162 (21%) Query: 20 AGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAGSASGGASGGSSGGAASGAG 79 A G GA + G G V VP V + V GL G A GA + A Sbjct: 514 AAGLGAGIPGLGVG---VGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAV 570 Query: 80 PGTQQGSPGWSQAGADGAAYTPPPVSPRFSFPGTTGSLAAAAAAAAAREA------AAYS 133 PG G G G P + AAAAA AAA+ A AA Sbjct: 571 PGVLGGLGALGGVGIPGGVVGAGPAA------------AAAAAKAAAKAAQFGLVGAAGL 618 Query: 134 SGGGAAGAGLAG--------------REQYGRAGFAGSYSSP 161 G G G G+ G +YG A G SP Sbjct: 619 GGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSP 660 >gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens] Length = 474 Score = 54.3 bits (129), Expect = 2e-07 Identities = 56/178 (31%), Positives = 70/178 (39%), Gaps = 40/178 (22%) Query: 4 SLAMAANHGPPPGAYEAGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAGSAS 63 S + AA+ P + GG G HG G GGG S + Sbjct: 142 SSSAAASSKPGEKGDKVGGSGGGGHGGG------------------------GGGGSSNA 177 Query: 64 GGASGGSSGGAASGAGPGTQQGSPGWSQAGADGAAYTPPPVSPRFSFPGTTGSLAAAAAA 123 GG GG+SGG A+ Q+ S G AG G + P + G G AAAAAA Sbjct: 178 GGGGGGASGGGANSKP--AQKKSCGSKVAGGAGGGVSKPHAKLILAGGGGGGKAAAAAAA 235 Query: 124 AAAREAAAYSSGGGAAGAGLAGREQYGRAGFAGSYSSPYPAYMADVGASWAAAAAASA 181 + A E A G AA L G A + S Y A AS ++AA+ASA Sbjct: 236 SFAAEQA-----GAAALLPL---------GAAADHHSLYKARTPSASASASSAASASA 279 Score = 34.7 bits (78), Expect = 0.18 Identities = 31/112 (27%), Positives = 52/112 (46%), Gaps = 16/112 (14%) Query: 29 GAGAASSPVY-VPTPRVPSSVLGLSYLQGGGAGSASGGASGGSSGGAASGAGPGTQQGSP 87 G G +SSPV V PS LGL +G G + SG SS ++ AG Sbjct: 301 GLGTSSSPVGGVGAGADPSDPLGLYEEEGAGCSPDAPSLSGRSSAASSPAAG-------- 352 Query: 88 GWSQAGADGAAYTPPPVSPRFSFPGTTGSLAAAAAAAAAREAAAYSSGGGAA 139 ++ AD Y S R + P + + + A+++A++ +++ SSG ++ Sbjct: 353 ---RSPADHRGY----ASLRAASPAPSSAPSHASSSASSHSSSSSSSGSSSS 397 Score = 32.3 bits (72), Expect = 0.88 Identities = 33/134 (24%), Positives = 45/134 (33%), Gaps = 33/134 (24%) Query: 54 LQGGGAGSASGGASG---GSSGGAASGAGPGTQQGSPGWSQAGADGAAYTPPPVSPRFSF 110 ++ G A S+S A+ G G G+G G G G + A G Sbjct: 134 VKSGNANSSSSAAASSKPGEKGDKVGGSGGGGHGGGGGGGSSNAGG-------------- 179 Query: 111 PGTTGSLAAAAAAAAAREAAAYSSGGGAAGAGLAGREQYGRAGFAGSYSSPYPAYMADVG 170 G A+ A ++ A S G AG G G S P+ + G Sbjct: 180 ----GGGGASGGGANSKPAQKKSCGSKVAG------------GAGGGVSKPHAKLILAGG 223 Query: 171 ASWAAAAAASAGPF 184 AAAA+A F Sbjct: 224 GGGGKAAAAAAASF 237 >gi|153792074 proline rich 12 [Homo sapiens] Length = 2036 Score = 54.3 bits (129), Expect = 2e-07 Identities = 63/189 (33%), Positives = 78/189 (41%), Gaps = 30/189 (15%) Query: 2 YQSLAMAANHGPPPGAY------EAGGPGAFM-HGAGAASSPVY--VPTPRVPS-SVLGL 51 YQ A A PPP A+ GG M H A A SP+ P+P S G Sbjct: 292 YQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGP 351 Query: 52 SYLQGGGAGSASG-------GASGGSSGGAASGAGPGTQQGSPGWSQAGADGAAYTPPPV 104 S G +G A+G GA GG G PG + G G+ A G A PPP Sbjct: 352 SGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAA--GGATRPPP- 408 Query: 105 SPRFSFPGTTGSLAAAAAAAAAREAAAYSSGGGAAGA-----GLAGREQYGRAGFAGSYS 159 PR + SL AAA A +A+ GG A + GL G + YG+ GF G + Sbjct: 409 -PRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAYGQ-GFGGGQA 466 Query: 160 ---SPYPAY 165 S P+Y Sbjct: 467 QDLSKAPSY 475 Score = 37.0 bits (84), Expect = 0.036 Identities = 59/225 (26%), Positives = 74/225 (32%), Gaps = 41/225 (18%) Query: 2 YQSLAMAANHGPPPGA------YEAGGPGAFM-----HGAGAASSPVYVPTPRVPSSVLG 50 Y + A A PPP + GGP A GAG A Y +P P +LG Sbjct: 396 YGAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAY--SPGQPQGLLG 453 Query: 51 LSYLQGGGAGSASGGASGGSSGGAASGAGPGTQQGSPGWSQA---------------GAD 95 Q G G G A S + SG P G P A G Sbjct: 454 P---QAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQ 510 Query: 96 GAAYTPPPVSPRFSFPGTTGSLAAAAAAAAAREAAAYSSGGGAAGAGLAGREQYGRAGFA 155 G Y P P + P + SL + + A GGG + L G + + Sbjct: 511 GEPY-PGPAAHSQGLPTASPSL----SYSTGHSPALSGHGGGWGPSSLGGGGEASPSHII 565 Query: 156 GSYSSPYPAYMADVGASWAAAAAASAGPFDSPVLHSLPGRANPAA 200 SP PA G + + G + S VL S P A P A Sbjct: 566 RPLQSP-PA----TGRPPGVGSPGAPGKYLSSVLASAPFLAPPGA 605 Score = 34.7 bits (78), Expect = 0.18 Identities = 38/133 (28%), Positives = 47/133 (35%), Gaps = 26/133 (19%) Query: 12 GPPPGAYEAGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAGSASGGASG--G 69 G PPG G PG ++ AS+P P GAGS + GA G G Sbjct: 575 GRPPGVGSPGAPGKYLSSV-LASAPFLAPP----------------GAGSYAAGAGGYKG 617 Query: 70 SSGGAASGAGPGTQQGSPGWSQAGADGAA--YTPPPVSPRFSFPGTTGSLAAAAAAAAAR 127 G+ AGPG G P + P PR S G G + AA A++ Sbjct: 618 KGDGSELLAGPG---GPPAERTEDEEFLIQHLLQAPSPPRTS--GADGLVGEDGAADASK 672 Query: 128 EAAAYSSGGGAAG 140 GG G Sbjct: 673 GLGGSGGAGGPPG 685 Score = 29.6 bits (65), Expect = 5.7 Identities = 31/101 (30%), Positives = 34/101 (33%), Gaps = 5/101 (4%) Query: 22 GPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGG-GAGSASGGASGGSSGGAASGAGP 80 GP A G AS + T P+ LS GG G S GG S P Sbjct: 516 GPAAHSQGLPTASPSLSYSTGHSPA----LSGHGGGWGPSSLGGGGEASPSHIIRPLQSP 571 Query: 81 GTQQGSPGWSQAGADGAAYTPPPVSPRFSFPGTTGSLAAAA 121 PG GA G + S F P GS AA A Sbjct: 572 PATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGA 612 Score = 28.9 bits (63), Expect = 9.8 Identities = 33/103 (32%), Positives = 40/103 (38%), Gaps = 29/103 (28%) Query: 42 PRVPSSVLGLSYLQGGGAGSASGGASGGSSGGAASGAGPG-TQQGSPGWSQAGADGAAYT 100 P VPSS LG L GGG +G GP T PG Sbjct: 197 PTVPSS-LGFERLAGGGVLGPAG-------------LGPAQTPPYRPG-----------P 231 Query: 101 PPPVSPRFSFPGTTGSLAAAAAAAAAREAAA---YSSGGGAAG 140 P P P P LA+++AAAAA E ++ Y+ G A G Sbjct: 232 PDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPG 274 >gi|110347449 POU domain, class 4, transcription factor 1 [Homo sapiens] Length = 419 Score = 53.1 bits (126), Expect = 5e-07 Identities = 50/149 (33%), Positives = 54/149 (36%), Gaps = 47/149 (31%) Query: 20 AGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAGSASGGASGGSSGGAASGAG 79 AGG GA G GA P GGG G GG GG GG G G Sbjct: 131 AGGAGAAAGGGGAHDGP-------------------GGGGGPGGGGGPGGGPGGGGGG-G 170 Query: 80 PGTQQGSPGWSQAG------------------ADGAAYTPPPVSPRFSFPGTT------G 115 PG G PG G A AA P P PG G Sbjct: 171 PGGGGGGPGGGLLGGSAHPHPHMHSLGHLSHPAAAAAMNMPSGLPH---PGLVAAAAHHG 227 Query: 116 SLAAAAAAAAAREAAAYSSGGGAAGAGLA 144 + AAAAAAAA + AAA ++ AGLA Sbjct: 228 AAAAAAAAAAGQVAAASAAAAVVGAAGLA 256 Score = 30.0 bits (66), Expect = 4.4 Identities = 32/110 (29%), Positives = 38/110 (34%), Gaps = 17/110 (15%) Query: 105 SPRFSFPGTTGSLAAAAAAAAAREAAAYSSG-----------GGAAGAGLAGREQYGRAG 153 SP + G AAA A + G GG G G G G Sbjct: 122 SPSLALMAGAGGAGAAAGGGGAHDGPGGGGGPGGGGGPGGGPGGGGGGGPGGGGGGPGGG 181 Query: 154 FAGSYSSPYPAYMADVG-ASWAAAAAASAGPFDSPVLHSLPGRANPAARH 202 G + P+P +M +G S AAAAA P P PG AA H Sbjct: 182 LLGGSAHPHP-HMHSLGHLSHPAAAAAMNMPSGLP----HPGLVAAAAHH 226 Score = 29.3 bits (64), Expect = 7.5 Identities = 29/103 (28%), Positives = 34/103 (33%), Gaps = 8/103 (7%) Query: 98 AYTPPPVSPRFSFPGTTGSLAAAAAAAAAREAAAYSSGGGAAGAGLAGREQYGRAGFAGS 157 A P + S P A A AAA A+ GG G G G G G G Sbjct: 110 ALEPGDLLDHISSPSLALMAGAGGAGAAAGGGGAHDGPGGGGGPGGGGGPGGGPGGGGGG 169 Query: 158 YSSPYPAYMADVGASWAAAAAASAGPFDSPVLHSLPGRANPAA 200 G SA P P +HSL ++PAA Sbjct: 170 GPG------GGGGGPGGGLLGGSAHP--HPHMHSLGHLSHPAA 204 >gi|33946327 nucleoporin 214kDa [Homo sapiens] Length = 2090 Score = 52.4 bits (124), Expect = 8e-07 Identities = 53/202 (26%), Positives = 80/202 (39%), Gaps = 31/202 (15%) Query: 13 PPPGAYEAGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAGSASGGASGGSSG 72 PP ++ G A A +++ PV V T P + S + G SA A G + Sbjct: 1583 PPASSFSVPGQTAVTAAAISSAGPVAVETSSTPIASSTTSIVAPGP--SAEAAAFGTVTS 1640 Query: 73 GAASGAGPGTQQGSPGWSQAGADGAAYTPPPVSPRFS----------FPGTTGSLAAAAA 122 G++ A P S ++Q + A T P +P F F TGS A+ AA Sbjct: 1641 GSSVFAQPPAASSSSAFNQLTNNTA--TAPSATPVFGQVAASTAPSLFGQQTGSTASTAA 1698 Query: 123 AAAAREAAAYSSGG-GAAGAGLAGREQYGRAGFAGSYSSPYPAYMADVGASWAAAAAASA 181 A ++ +SS G G+ G+ +G+A G +A++AAS Sbjct: 1699 ATPQVSSSGFSSPAFGTTAPGVFGQTTFGQASVFGQ----------------SASSAASV 1742 Query: 182 GPFDSPVLHSLPGRANPAARHP 203 F P S+P PA+ P Sbjct: 1743 FSFSQPGFSSVPAFGQPASSTP 1764 Score = 43.5 bits (101), Expect = 4e-04 Identities = 50/182 (27%), Positives = 69/182 (37%), Gaps = 15/182 (8%) Query: 30 AGAASSPVYVPTPRVPSSVLGLSYLQGGGAGSASGGASGGSSGGAASGAGPGTQQGSPGW 89 A AA++P +P + + S L GGA + S G++S T G P Sbjct: 449 ASAAAAPASLPPSSPAAPIATFSLLPAGGAPTVF-------SFGSSSLKSSATVTGEPPS 501 Query: 90 SQAGADGAAYTPPPVSPRFSF-PGTTGSLA-AAAAAAAAREAAAYSSGGGAAGAGLAGR- 146 +G+D + P P FSF P + SLA AA+ A AA++S G L Sbjct: 502 YSSGSDSSKAAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFSFGSSGFKPTLESTP 561 Query: 147 -EQYGRAGFAGSYSSPYPAYMADVGASWAAAAAASAGPFDS----PVLHSLPGRANPAAR 201 A S P V S AAA++ P S P + + PAA Sbjct: 562 VPSVSAPNIAMKPSFPPSTSAVKVNLSEKFTAAATSTPVSSSQSAPPMSPFSSASKPAAS 621 Query: 202 HP 203 P Sbjct: 622 GP 623 Score = 36.2 bits (82), Expect = 0.061 Identities = 34/137 (24%), Positives = 54/137 (39%), Gaps = 9/137 (6%) Query: 59 AGSASGGASGGSSGGAASGAGPGTQQGSPGWSQAGADGAAYTPPPVSPRFSFPGTTGSLA 118 +GS G + G GG SG G Q + + + + S + G +G+ Sbjct: 1870 SGSVFGSGNTGRGGGFFSGLGGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSGAKT 1929 Query: 119 ----AAAAAAAAREAAAYSSGGGAA---GAGLAGREQYGRAGFAGSYSSPYPAYMADVGA 171 A+++ + +SSGGG+ G G + + G G A + SP P + G Sbjct: 1930 FGGFASSSFGEQKPTGTFSSGGGSVASQGFGFSSPNKTGGFGAAPVFGSP-PTFGGSPGF 1988 Query: 172 SWAAAAAASAGPFDSPV 188 A SA F SP+ Sbjct: 1989 G-GVPAFGSAPAFTSPL 2004 Score = 32.3 bits (72), Expect = 0.88 Identities = 32/95 (33%), Positives = 41/95 (43%), Gaps = 11/95 (11%) Query: 330 TPAAPSGSESLPPASGASSNSSNATTSSSEEMRPIKTEPGLSSHYGHSSSVSQTFSVSAM 389 +PAAP + SL PA GA + S ++S P SS G SS A Sbjct: 462 SPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSS--GSDSS-------KAA 512 Query: 390 SGHGPSIHPVL--SALKLSPQGYASPVSQSPQTSS 422 G GPS + S L+P ASPV+ S + S Sbjct: 513 PGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFS 547 Score = 31.6 bits (70), Expect = 1.5 Identities = 44/182 (24%), Positives = 68/182 (37%), Gaps = 34/182 (18%) Query: 23 PGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAGSASGGASGGSSGGAASGAGPGT 82 P F G+ +S TP+V SS G S G+ + G G ++ G AS G Sbjct: 1683 PSLFGQQTGSTASTA-AATPQVSSS--GFS---SPAFGTTAPGVFGQTTFGQASVFGQSA 1736 Query: 83 QQGS-------PGWSQAGADGAAYTPPPVSPR---------------FSF----PGTTGS 116 + PG+S A G + P S FSF P T G Sbjct: 1737 SSAASVFSFSQPGFSSVPAFGQPASSTPTSTSGSVFGAASSTSSSSSFSFGQSSPNTGGG 1796 Query: 117 LAAAAAAAAAREAAAYSSGGGAAGAGLAGREQYGRAGFAGSYSSPYPAYMADVGASWAAA 176 L + A A ++ + GG G A +GF+ +S + + ++ G+ + A Sbjct: 1797 LFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTAATSGFSFCQASGFGS--SNTGSVFGQA 1854 Query: 177 AA 178 A+ Sbjct: 1855 AS 1856 Score = 30.4 bits (67), Expect = 3.4 Identities = 31/96 (32%), Positives = 42/96 (43%), Gaps = 19/96 (19%) Query: 52 SYLQGGGAGSASG-GASG----GSSGGAASGAGPGTQQGSPGWSQAGADGAAYTPPPVSP 106 ++ GGG+ ++ G G S G G A P T GSPG+ A G+A P Sbjct: 1946 TFSSGGGSVASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSA-------P 1998 Query: 107 RFSFP-GTTGSLAAAAAAAAAREAAAYSSGGGAAGA 141 F+ P G+TG AAA S+GG G+ Sbjct: 1999 AFTSPLGSTGGKVFGEGTAAA------SAGGFGFGS 2028 Score = 29.6 bits (65), Expect = 5.7 Identities = 37/163 (22%), Positives = 53/163 (32%), Gaps = 13/163 (7%) Query: 8 AANHGPPPGAYEAGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAGSASGGAS 67 +++ G G+ G G F G G S S+ G + G + Sbjct: 1867 SSSSGSVFGSGNTGRGGGFFSGLGGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSG 1926 Query: 68 GGSSGGAAS---GAGPGTQQGSPGWSQAGADGAAYTPPP------VSPRFSFPGTTGSLA 118 + GG AS G T S G + G ++ P +P F P T G Sbjct: 1927 AKTFGGFASSSFGEQKPTGTFSSGGGSVASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSP 1986 Query: 119 AAAAAAAAREAAAYSSGGGAAGAGLAGR----EQYGRAGFAGS 157 A A A++S G+ G + G G GF S Sbjct: 1987 GFGGVPAFGSAPAFTSPLGSTGGKVFGEGTAAASAGGFGFGSS 2029 >gi|195972866 keratin 10 [Homo sapiens] Length = 584 Score = 52.0 bits (123), Expect = 1e-06 Identities = 37/112 (33%), Positives = 47/112 (41%), Gaps = 18/112 (16%) Query: 56 GGGAGSASGGASGGSSGGAASGA--GPGTQQGSPGWSQAGADGAAYTPPPVSPRFSFPGT 113 GG GS+ GG GGSSGG +SG G G+ G G S +G G S G Sbjct: 489 GGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGG----------SSGGG 538 Query: 114 TGSLAAAAAAAAAREAAAYSSGGGAAGAGLAGREQYGRAGFAGSYSSPYPAY 165 G ++ + SSGGG G +G + +G G SS P Y Sbjct: 539 GGGYGGGSSGGGS------SSGGGYGGGSSSGGHKSSSSGSVGESSSKGPRY 584 Score = 44.3 bits (103), Expect = 2e-04 Identities = 33/114 (28%), Positives = 47/114 (41%), Gaps = 6/114 (5%) Query: 52 SYLQGGGAGSASGGASGGSSGGAASG--AGPGTQQGSPGWSQAGADGAAY---TPPPVSP 106 S L+G G+ S GG GGS GG G +G G+ G G G+ G Y + S Sbjct: 451 SLLEGEGS-SGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSS 509 Query: 107 RFSFPGTTGSLAAAAAAAAAREAAAYSSGGGAAGAGLAGREQYGRAGFAGSYSS 160 + G + S +++ + GGG G G +G G+ G SS Sbjct: 510 GGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSS 563 Score = 42.7 bits (99), Expect = 7e-04 Identities = 43/143 (30%), Positives = 57/143 (39%), Gaps = 27/143 (18%) Query: 21 GGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAGSASGGASGGSSGGAASGAGP 80 GG G G G SS R+ SS L G G +SGG SGGS +SG G Sbjct: 19 GGGGGGCGGGGGVSSL------RISSSKGSL------GGGFSSGGFSGGSFSRGSSGGGC 66 Query: 81 -GTQQGSPGWSQAGADGAAYTPPPVSPRFSFPGTTGSLAAAAAAAAAREAAAYSSGGGAA 139 G G G+ G G SF G+ GS + + + ++ GGG+ Sbjct: 67 FGGSSG--GYGGLGGFGGG----------SFRGSYGSSSFGGSYGGSFGGGSF--GGGSF 112 Query: 140 GAGLAGREQYGRAGFAGSYSSPY 162 G G G +G GF G + + Sbjct: 113 GGGSFGGGGFGGGGFGGGFGGGF 135 Score = 38.1 bits (87), Expect = 0.016 Identities = 25/86 (29%), Positives = 32/86 (37%), Gaps = 16/86 (18%) Query: 11 HGPPPGAYEAGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAGSASGGASGGS 70 HG G GG G G G++ G Y G +G G +SGG Sbjct: 487 HGGGHGGSSGGGYGGGSSGGGSS----------------GGGYGGGSSSGGHGGSSSGGY 530 Query: 71 SGGAASGAGPGTQQGSPGWSQAGADG 96 GG++ G G G GS G + G Sbjct: 531 GGGSSGGGGGGYGGGSSGGGSSSGGG 556 Score = 35.8 bits (81), Expect = 0.080 Identities = 31/114 (27%), Positives = 43/114 (37%), Gaps = 17/114 (14%) Query: 59 AGSASGGASGG---SSGGAASGAGPGTQQGS--PGWSQAGADGAAYTPPPVSPRFSFPGT 113 + S SGG GG GG S + +GS G+S G G +++ S F G+ Sbjct: 12 SSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGS-SGGGCFGGS 70 Query: 114 TGSLAAAAAAAAAREAAAYSS-----------GGGAAGAGLAGREQYGRAGFAG 156 +G +Y S GGG+ G G G +G GF G Sbjct: 71 SGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGGFGG 124 Score = 30.0 bits (66), Expect = 4.4 Identities = 30/85 (35%), Positives = 32/85 (37%), Gaps = 13/85 (15%) Query: 12 GPPPGAYEAGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAGSASGGASGGSS 71 G G Y GG G F G+ S SS G SY G GS GG+ GG S Sbjct: 68 GGSSGGY--GGLGGFGGGSFRGS---------YGSSSFGGSYGGSFGGGSFGGGSFGGGS 116 Query: 72 GGAASGAGPGTQQGSPGWSQAGADG 96 G G G G G G DG Sbjct: 117 FGGGGFGGGGFGGGFGG--GFGGDG 139 Score = 29.3 bits (64), Expect = 7.5 Identities = 25/71 (35%), Positives = 27/71 (38%), Gaps = 14/71 (19%) Query: 12 GPPPGAYEAGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAGSASGGASGGSS 71 G G Y G G G G SS G S G G GS+SGG SS Sbjct: 524 GSSSGGYGGGSSGGGGGGYGGGSSGG------------GSSSGGGYGGGSSSGGHKSSSS 571 Query: 72 G--GAASGAGP 80 G G +S GP Sbjct: 572 GSVGESSSKGP 582 >gi|109255251 loricrin [Homo sapiens] Length = 312 Score = 52.0 bits (123), Expect = 1e-06 Identities = 40/134 (29%), Positives = 55/134 (41%), Gaps = 14/134 (10%) Query: 40 PTPRVPSSVLGLSYLQGGGAGSASGGAS---GGSSGGAASGAGPGTQQG----------- 85 PTP+ P + S GGG GS GG GG SGG +SG+G G G Sbjct: 8 PTPQPPVDCVKTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGG 67 Query: 86 SPGWSQAGADGAAYTPPPVSPRFSFPGTTGSLAAAAAAAAAREAAAYSSGGGAAGAGLAG 145 S G G G S ++S G + + ++ + +SSGGG + G +G Sbjct: 68 SSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSG 127 Query: 146 REQYGRAGFAGSYS 159 G G +G S Sbjct: 128 CFSSGGGGSSGGGS 141 Score = 48.9 bits (115), Expect = 9e-06 Identities = 51/188 (27%), Positives = 68/188 (36%), Gaps = 19/188 (10%) Query: 16 GAYEAGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAGSASGGASGGSSGGAA 75 G GG G F G G S S G S GGG+G S G GGS G Sbjct: 134 GGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSS---GGGSGCFSSGGGGGSVCG-Y 189 Query: 76 SGAGPGTQQGSPGWSQAG-ADGAAYTPPPVSPRFSFPGTTGSLAAAAAAAAAREAAAYSS 134 SG G G GS G S +G T +P+ S+ G ++ + + +SS Sbjct: 190 SGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGG------GSSGGGGSGGSGCFSS 243 Query: 135 GGGAAGAGLAGREQYGRAGFAGSYSSPYPAYMADVGASWAAAAAASAGPFDS----PVLH 190 GGG +G G G +G + G+S +S G S P+ H Sbjct: 244 GGGGGSSGCGG----GSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSGKGVPICH 299 Query: 191 SLPGRANP 198 + P Sbjct: 300 QTQQKQAP 307 Score = 44.7 bits (104), Expect = 2e-04 Identities = 49/177 (27%), Positives = 62/177 (35%), Gaps = 33/177 (18%) Query: 16 GAYEAGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAGSASGGASG--GSSGG 73 G GG G F G G G GG GS SGG SG S GG Sbjct: 94 GGSSGGGSGCFSSGGG------------------GSGCFSSGGGGS-SGGGSGCFSSGGG 134 Query: 74 AASGAGPGT-QQGSPGWSQAGADGAAYTPPPVSPRFSFPGTTGSLAAAAAAAAAREAAAY 132 +SG G G G G+S +Y VS S G +G ++ + Y Sbjct: 135 GSSGGGSGCFSSGGGGFSGQAVQCQSY--GGVSSGGSSGGGSGCFSSGGGGGS---VCGY 189 Query: 133 SSGGGAAGAGLAGREQYGRAG---FAGSYSSPYPAYMADVGASWAAAAAASAGPFDS 186 S GG G G +G G + +P P+Y G S + +G F S Sbjct: 190 SGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSY---GGGSSGGGGSGGSGCFSS 243 Score = 42.7 bits (99), Expect = 7e-04 Identities = 42/152 (27%), Positives = 51/152 (33%), Gaps = 36/152 (23%) Query: 3 QSLAMAANHGPPPGAYEAGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAGSA 62 Q++ + G G GG G F G G SV G S GGG+G Sbjct: 154 QAVQCQSYGGVSSGGSSGGGSGCFSSGGGG-------------GSVCGYS---GGGSG-C 196 Query: 63 SGGASGGSSGGAAS---------GAGPGTQQGSPGWSQAGADGAAYTPPPVSPRFSFPGT 113 GG+SGGS G S P GS G +G G FS G Sbjct: 197 GGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGC----------FSSGGG 246 Query: 114 TGSLAAAAAAAAAREAAAYSSGGGAAGAGLAG 145 GS ++ S GG G G +G Sbjct: 247 GGSSGCGGGSSGIGSGCIISGGGSVCGGGSSG 278 Score = 40.8 bits (94), Expect = 0.002 Identities = 28/76 (36%), Positives = 34/76 (44%), Gaps = 6/76 (7%) Query: 12 GPPPGAYEAGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAGSASGGASGGSS 71 G G +GG G F G G SS SS +G + GG GS GG S G Sbjct: 227 GGSSGGGGSGGSGCFSSGGGGGSSGC-----GGGSSGIGSGCIISGG-GSVCGGGSSGGG 280 Query: 72 GGAASGAGPGTQQGSP 87 GG +S G G+ +G P Sbjct: 281 GGGSSVGGSGSGKGVP 296 >gi|210147522 zinc finger, SWIM-type containing 6 [Homo sapiens] Length = 1215 Score = 51.6 bits (122), Expect = 1e-06 Identities = 52/161 (32%), Positives = 61/161 (37%), Gaps = 36/161 (22%) Query: 56 GGGAGSASGGASGGSSGGAASGAGPGTQQGSPGWSQAGADGAAYTPPPVSPRFSFPGTTG 115 GGG G S G GG+ GG +S PG + G + A GAA P S P + Sbjct: 20 GGGGGGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGGAALGLLPPGKTQS-PESLL 78 Query: 116 SLAAAAAAA-----------------------------AAREAAAYSS---GGGAAGA-- 141 +AA A + RE YSS GGGAAG Sbjct: 79 DIAARRVAEKWPFQRVEERFERIPEPVQRRIVYWSFPRSEREICMYSSFNTGGGAAGGPG 138 Query: 142 -GLAGREQYGRAGFAGSYSSPYPAYMADVGASWAAAAAASA 181 G G G GS SSP A A+ AAAAAA+A Sbjct: 139 DDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAA 179 Score = 50.1 bits (118), Expect = 4e-06 Identities = 41/115 (35%), Positives = 48/115 (41%), Gaps = 25/115 (21%) Query: 37 VYVPTPRVPSSV-LGLSYLQGGGAGSASGGASGGSSGGAASGAGPGTQQGSPGWSQAGAD 95 VY PR + + S+ GGGA G SGG GG A G G G SP + A A Sbjct: 110 VYWSFPRSEREICMYSSFNTGGGAAGGPGDDSGG--GGGAGGGGGGGSSSSPAATSAAAT 167 Query: 96 GAAYTPPPVSPRFSFPGTTGSLAAAAAAAAAREAAAYSSGGGAAGAGLAGREQYG 150 +AAAAAAAA AAA ++G GA G AG G Sbjct: 168 ----------------------SAAAAAAAAAAAAAAAAGAGAPSVGAAGAADGG 200 Score = 42.0 bits (97), Expect = 0.001 Identities = 31/89 (34%), Positives = 41/89 (46%), Gaps = 16/89 (17%) Query: 67 SGGSSGGAASGAGPGTQQGSPGWSQAGADGAAYTPPPVSPRFSFPGTTGSLAAAAAAAAA 126 S ++GG A+G GPG G G + G G G++ S AA +AAA + Sbjct: 125 SSFNTGGGAAG-GPGDDSGGGGGAGGGGGG---------------GSSSSPAATSAAATS 168 Query: 127 REAAAYSSGGGAAGAGLAGREQYGRAGFA 155 AAA ++ AA A AG G AG A Sbjct: 169 AAAAAAAAAAAAAAAAGAGAPSVGAAGAA 197 Score = 33.9 bits (76), Expect = 0.30 Identities = 22/77 (28%), Positives = 28/77 (36%) Query: 1 MYQSLAMAANHGPPPGAYEAGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAG 60 MY S PG GG GA G G +SS + S+ + A Sbjct: 123 MYSSFNTGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAA 182 Query: 61 SASGGASGGSSGGAASG 77 +A GA + GAA G Sbjct: 183 AAGAGAPSVGAAGAADG 199 >gi|119395750 keratin 1 [Homo sapiens] Length = 644 Score = 51.2 bits (121), Expect = 2e-06 Identities = 45/141 (31%), Positives = 61/141 (43%), Gaps = 11/141 (7%) Query: 22 GPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAGSASGGASGGSSGGA-ASGAGP 80 G + M G A + V V T +++ G GGG G SGG+S GS GG+ SG G Sbjct: 488 GEESRMSGECAPNVSVSVSTSH--TTISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGG 545 Query: 81 GTQQGS--PGWSQAGADGAAYTPPPVSPRFSFPGTTGSLAAAAAAAAAREAAAYSSGGGA 138 G +GS G S G+ G +Y G GS + +++ R + GG + Sbjct: 546 GGGRGSYGSGGSSYGSGGGSYGSG------GGGGGHGSYGSGSSSGGYRGGSGGGGGGSS 599 Query: 139 AGAGLAGREQYGRAGFAGSYS 159 G G G G G GS S Sbjct: 600 GGRGSGGGSSGGSIGGRGSSS 620 Score = 40.4 bits (93), Expect = 0.003 Identities = 32/96 (33%), Positives = 43/96 (44%), Gaps = 19/96 (19%) Query: 9 ANHGPPPGAYEAGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGG--------GAG 60 +++G G+Y +GG G G+ + Y G SY GG G+G Sbjct: 530 SSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSG--------GGSYGSGGGGGGHGSYGSG 581 Query: 61 SASGGASGGSSGGAASGAGPGTQQGSPGWSQAGADG 96 S+SGG GGS GG G G +GS G S G+ G Sbjct: 582 SSSGGYRGGSGGG---GGGSSGGRGSGGGSSGGSIG 614 Score = 36.2 bits (82), Expect = 0.061 Identities = 26/82 (31%), Positives = 34/82 (41%), Gaps = 6/82 (7%) Query: 21 GGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAGSASGGASGG---SSGGAASG 77 GG G+F G G S + S + +S +GGG GS GG GG GG G Sbjct: 51 GGGGSFGAGGGFGSRSL---VNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGG 107 Query: 78 AGPGTQQGSPGWSQAGADGAAY 99 G G G+ G+ G + Sbjct: 108 GFGGGGIGGGGFGGFGSGGGGF 129 Score = 35.0 bits (79), Expect = 0.14 Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 17/81 (20%) Query: 9 ANHGPPPGAYEAGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAGSASGGASG 68 +++G G+Y +GG G G+ SS S GG+G GG+SG Sbjct: 557 SSYGSGGGSYGSGGGGGGHGSYGSGSS----------------SGGYRGGSGGGGGGSSG 600 Query: 69 G-SSGGAASGAGPGTQQGSPG 88 G SGG +SG G + S G Sbjct: 601 GRGSGGGSSGGSIGGRGSSSG 621 Score = 33.9 bits (76), Expect = 0.30 Identities = 30/115 (26%), Positives = 38/115 (33%), Gaps = 13/115 (11%) Query: 56 GGGAGSASGGASGGSSGGAASGAGP-------GTQQGSPGWSQAGADGAAYTPPPVSPRF 108 GGG G S GG S GA G G G++ S ++ G G+ + F Sbjct: 40 GGGGGRFSSCGGGGGSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGF 99 Query: 109 SFPGTTGSLAAAAAAAAAREAAAYSSGGGAAGAGLAGREQYGRAGFAGSYSSPYP 163 G G S GGG G G +G G+ G Y P Sbjct: 100 GGGGFGGGGFGGGGIGGGGFGGFGSGGGGFGGGG------FGGGGYGGGYGPVCP 148 Score = 31.6 bits (70), Expect = 1.5 Identities = 25/87 (28%), Positives = 33/87 (37%), Gaps = 4/87 (4%) Query: 16 GAYEAGG---PGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAGSASGGASGGSSG 72 G++ AGG + ++ G+ S + V S G Y GGG G G G G Sbjct: 54 GSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGY-GGGGFGGGGFGGGGFGGG 112 Query: 73 GAASGAGPGTQQGSPGWSQAGADGAAY 99 G G G G G+ G G Y Sbjct: 113 GIGGGGFGGFGSGGGGFGGGGFGGGGY 139 Score = 31.2 bits (69), Expect = 2.0 Identities = 17/45 (37%), Positives = 17/45 (37%) Query: 57 GGAGSASGGASGGSSGGAASGAGPGTQQGSPGWSQAGADGAAYTP 101 GG G GG GG GG SG G G G G G P Sbjct: 105 GGGGFGGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGYGPVCPP 149 >gi|55956899 keratin 9 [Homo sapiens] Length = 623 Score = 50.4 bits (119), Expect = 3e-06 Identities = 42/148 (28%), Positives = 55/148 (37%), Gaps = 27/148 (18%) Query: 10 NHGPPPGAYEAGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAGSASGGASGG 69 + G G+Y GG G +G G+ S G SY G G+G SGG GG Sbjct: 489 SRGGSGGSYGGGGSGGG-YGGGSGSR-----------GGSGGSYGGGSGSGGGSGGGYGG 536 Query: 70 SSGGAASGAGPGTQQGSPGWSQAGADGAAYTPPPVSPRFSFPGTTGSLAAAAAAAAAREA 129 SGG SG G G G + G G+ GS + +R Sbjct: 537 GSGGGHSGGSGGGHSGGSGGNYGGGSGSG---------------GGSGGGYGGGSGSRGG 581 Query: 130 AAYSSGGGAAGAGLAGREQYGRAGFAGS 157 + S GGG+ G +G G +GS Sbjct: 582 SGGSHGGGSGFGGESGGSYGGGEEASGS 609 Score = 46.6 bits (109), Expect = 5e-05 Identities = 36/125 (28%), Positives = 45/125 (36%), Gaps = 16/125 (12%) Query: 56 GGGAGSASGGASGGSSGGAASGAGPGTQQGSPGWSQAGADGAAYTPPPVSPRFSFPGTTG 115 GG G S G SGGS GG SG G G GS G G+ G S+ G +G Sbjct: 482 GGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRG----GSGG------------SYGGGSG 525 Query: 116 SLAAAAAAAAAREAAAYSSGGGAAGAGLAGREQYGRAGFAGSYSSPYPAYMADVGASWAA 175 S + +S G G +G +G G +G G Y G S + Sbjct: 526 SGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGS 585 Query: 176 AAAAS 180 S Sbjct: 586 HGGGS 590 Score = 43.1 bits (100), Expect = 5e-04 Identities = 40/137 (29%), Positives = 52/137 (37%), Gaps = 14/137 (10%) Query: 20 AGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAGSASGGASGGSSGGAASGAG 79 +GG G G+G + Y R SS G GGG S+S G GGSS G G Sbjct: 14 SGGGGGGGLGSGGSIRSSY---SRFSSSGGG----GGGGRFSSSSGYGGGSSRVCGRGGG 66 Query: 80 PGTQQGSPGWSQAGADGAAYTPPPVSPRFSFPGTTGSLAAAAAAAAAREAAAYSSGGGAA 139 GS G+S G G ++ + F G + A+ + GG + Sbjct: 67 -----GSFGYSYGGGSGGGFSASSLGG--GFGGGSRGFGGASGGGYSSSGGFGGGFGGGS 119 Query: 140 GAGLAGREQYGRAGFAG 156 G G G G GF G Sbjct: 120 GGGFGGGYGSGFGGFGG 136 Score = 40.8 bits (94), Expect = 0.002 Identities = 33/121 (27%), Positives = 42/121 (34%), Gaps = 10/121 (8%) Query: 50 GLSYLQGGGAGSASGGASGGSSGGAASGAGP--------GTQQGSPGWSQAGADGAAYTP 101 G SY +G GS GGS GG G+G G GS G S G G + Sbjct: 482 GGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGG 541 Query: 102 PPVSPRFSFPGTTGSLAAAAAAAAAREAAAYSSGGGAAGAGLAGREQYGRAGFAGSYSSP 161 G +G + + Y GGG+ G +G G +GF G Sbjct: 542 HSGGSGGGHSGGSGGNYGGGSGSGGGSGGGY--GGGSGSRGGSGGSHGGGSGFGGESGGS 599 Query: 162 Y 162 Y Sbjct: 600 Y 600 Score = 34.7 bits (78), Expect = 0.18 Identities = 32/98 (32%), Positives = 39/98 (39%), Gaps = 8/98 (8%) Query: 50 GLSYLQGGGAGSASGGASGGSSGG--AASGAGPGTQQGSPGWSQAGADGAAYTPPPVSPR 107 G S + G G G + G + GG SGG +AS G G GS G+ GA G Y+ S Sbjct: 56 GSSRVCGRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGF--GGASGGGYSS---SGG 110 Query: 108 FSFPGTTGSLAAAAAAAAAREAAAYSSGGGAAGAGLAG 145 F G G + GG AG G G Sbjct: 111 FG-GGFGGGSGGGFGGGYGSGFGGFGGFGGGAGGGDGG 147 Score = 34.3 bits (77), Expect = 0.23 Identities = 29/93 (31%), Positives = 37/93 (39%), Gaps = 19/93 (20%) Query: 21 GGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQG--------GGAGSASGGASGGSSG 72 GG G+F + G S + +S LG + G GG S+SGG GG G Sbjct: 64 GGGGSFGYSYGGGSGGGF------SASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGG 117 Query: 73 GAASGAGPGTQQGSPGW-----SQAGADGAAYT 100 G+ G G G G G+ G DG T Sbjct: 118 GSGGGFGGGYGSGFGGFGGFGGGAGGGDGGILT 150 Score = 33.1 bits (74), Expect = 0.52 Identities = 20/46 (43%), Positives = 23/46 (50%), Gaps = 5/46 (10%) Query: 56 GGGAGSASGGASGGSSGGAASGAGPGTQQGSP--GWSQAGADGAAY 99 G G GS S G SGGS GG G+G G + G G +A G Y Sbjct: 571 GYGGGSGSRGGSGGSHGG---GSGFGGESGGSYGGGEEASGSGGGY 613 Score = 32.3 bits (72), Expect = 0.88 Identities = 27/106 (25%), Positives = 39/106 (36%), Gaps = 11/106 (10%) Query: 61 SASGGASGGSSGGAASGAGPGTQQGSPGWSQAGADGAAYTPPPVSPRFSFPGTTGSLAAA 120 S+S + G GG G+G + +S +G G RFS G ++ Sbjct: 7 SSSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGG-------GRFSSSSGYGGGSSR 59 Query: 121 AAAAAAREAAAYSSGGGAAG----AGLAGREQYGRAGFAGSYSSPY 162 + YS GGG+ G + L G G GF G+ Y Sbjct: 60 VCGRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGY 105 Score = 32.0 bits (71), Expect = 1.2 Identities = 18/31 (58%), Positives = 19/31 (61%), Gaps = 2/31 (6%) Query: 58 GAGSASGGASGGSSGGA--ASGAGPGTQQGS 86 G GS GG SGGS GG ASG+G G GS Sbjct: 587 GGGSGFGGESGGSYGGGEEASGSGGGYGGGS 617 Score = 29.6 bits (65), Expect = 5.7 Identities = 16/41 (39%), Positives = 19/41 (46%) Query: 50 GLSYLQGGGAGSASGGASGGSSGGAASGAGPGTQQGSPGWS 90 G S+ G G G SGG+ GG + SG G G G S Sbjct: 583 GGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSGKSSHS 623 >gi|239757043 PREDICTED: functional smad suppressing element 18 [Homo sapiens] Length = 996 Score = 50.4 bits (119), Expect = 3e-06 Identities = 56/171 (32%), Positives = 70/171 (40%), Gaps = 33/171 (19%) Query: 13 PPPGAYEAGGPGA------FMHGAGAASSPVYVPTPRVPSSVLGLSYLQG-GGAGSASGG 65 PPP A AG P A F + V + ++ LS GGAG+ GG Sbjct: 292 PPPLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGGG 351 Query: 66 ASGGSSGGAASGAGPGTQQGSPGWSQAGADG-AAYTPPPVSPRFS-------FPGTTG-- 115 A GG G GAG G G AGA G +Y PV + S FPG G Sbjct: 352 AGGGCVAGVGVGAGAGAGAG------AGAKGPRSYPVIPVPSKGSFGGVLQKFPGCGGLF 405 Query: 116 ----SLAAAAAAAA----AREAAAYSSGGGAAGAGLAGREQYGRAGFAGSY 158 + AAAAA + +A A + G AGAG AG +AG +G + Sbjct: 406 PHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAGAGGAGAAP--KAGLSGLF 454 Score = 41.6 bits (96), Expect = 0.001 Identities = 49/178 (27%), Positives = 58/178 (32%), Gaps = 19/178 (10%) Query: 31 GAASSPVYVPTPRVPSSVLGLSYLQ---------------GGGAGSASGGASGGSSGGAA 75 G P Y+ P P S LG + + GG AGSA G Sbjct: 477 GGLPVPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVV 536 Query: 76 SGAGPGTQQGSPGWSQAGADGAAYTPPPVSPRFSFPGTTGSLAAAAAAAAAREAAAYSSG 135 + GPG+ P D +PP S G+T + AAA A AA Sbjct: 537 AN-GPGSGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPA 595 Query: 136 GGAAGAGLAGREQYGRAGFAGSY---SSPYPAYMADVGASWAAAAAASAGPFDSPVLH 190 G A GR GSY S+ P D S A ASAG S H Sbjct: 596 GSRVPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGAPHSAQTH 653 Score = 32.0 bits (71), Expect = 1.2 Identities = 52/190 (27%), Positives = 63/190 (33%), Gaps = 56/190 (29%) Query: 63 SGGASGGSSGGAASGAGPGTQQGSPG-WSQAGADGAAYTP-----PPVSP---------- 106 +G A+ G A GAG + G G + AG A Y P PP +P Sbjct: 427 AGAAAEALGGAGAGGAGAAPKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLPVPTYLQ 486 Query: 107 --------------------RFSF------PGTTGSLAAAAAAAAAREAAAYSSGGG--- 137 R +F G GS AA + A G G Sbjct: 487 PPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGPGSGPPP 546 Query: 138 -AAGAGLAGREQYGRAGFAGSYSSPYPAYMAD-VGASWAAAAAASAGPFDSPVLHSLPGR 195 A GAG G +G S AD V A+ A AAAA +GP S V Sbjct: 547 PAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRV------- 599 Query: 196 ANPAARHPNL 205 PA HP+L Sbjct: 600 --PAPHHPHL 607 Score = 29.3 bits (64), Expect = 7.5 Identities = 24/84 (28%), Positives = 33/84 (39%), Gaps = 2/84 (2%) Query: 8 AANHGPPPGAYEAGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAGSASGGAS 67 +A PP + A G GA G+G A S VP P P + G G S++ Sbjct: 570 SAGSTPPADSVAAAGAGAAAAGSGPAGS--RVPAPHHPHLLEGRKAGGGSYHHSSAFRPV 627 Query: 68 GGSSGGAASGAGPGTQQGSPGWSQ 91 GG + G G+P +Q Sbjct: 628 GGKDDAESLAKLHGASAGAPHSAQ 651 >gi|239751555 PREDICTED: functional smad suppressing element 18 [Homo sapiens] Length = 1252 Score = 50.4 bits (119), Expect = 3e-06 Identities = 56/171 (32%), Positives = 70/171 (40%), Gaps = 33/171 (19%) Query: 13 PPPGAYEAGGPGA------FMHGAGAASSPVYVPTPRVPSSVLGLSYLQG-GGAGSASGG 65 PPP A AG P A F + V + ++ LS GGAG+ GG Sbjct: 292 PPPLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGGG 351 Query: 66 ASGGSSGGAASGAGPGTQQGSPGWSQAGADG-AAYTPPPVSPRFS-------FPGTTG-- 115 A GG G GAG G G AGA G +Y PV + S FPG G Sbjct: 352 AGGGCVAGVGVGAGAGAGAG------AGAKGPRSYPVIPVPSKGSFGGVLQKFPGCGGLF 405 Query: 116 ----SLAAAAAAAA----AREAAAYSSGGGAAGAGLAGREQYGRAGFAGSY 158 + AAAAA + +A A + G AGAG AG +AG +G + Sbjct: 406 PHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAGAGGAGAAP--KAGLSGLF 454 Score = 41.6 bits (96), Expect = 0.001 Identities = 49/178 (27%), Positives = 58/178 (32%), Gaps = 19/178 (10%) Query: 31 GAASSPVYVPTPRVPSSVLGLSYLQ---------------GGGAGSASGGASGGSSGGAA 75 G P Y+ P P S LG + + GG AGSA G Sbjct: 477 GGLPVPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVV 536 Query: 76 SGAGPGTQQGSPGWSQAGADGAAYTPPPVSPRFSFPGTTGSLAAAAAAAAAREAAAYSSG 135 + GPG+ P D +PP S G+T + AAA A AA Sbjct: 537 AN-GPGSGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPA 595 Query: 136 GGAAGAGLAGREQYGRAGFAGSY---SSPYPAYMADVGASWAAAAAASAGPFDSPVLH 190 G A GR GSY S+ P D S A ASAG S H Sbjct: 596 GSRVPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGAPHSAQTH 653 Score = 32.0 bits (71), Expect = 1.2 Identities = 52/190 (27%), Positives = 63/190 (33%), Gaps = 56/190 (29%) Query: 63 SGGASGGSSGGAASGAGPGTQQGSPG-WSQAGADGAAYTP-----PPVSP---------- 106 +G A+ G A GAG + G G + AG A Y P PP +P Sbjct: 427 AGAAAEALGGAGAGGAGAAPKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLPVPTYLQ 486 Query: 107 --------------------RFSF------PGTTGSLAAAAAAAAAREAAAYSSGGG--- 137 R +F G GS AA + A G G Sbjct: 487 PPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGPGSGPPP 546 Query: 138 -AAGAGLAGREQYGRAGFAGSYSSPYPAYMAD-VGASWAAAAAASAGPFDSPVLHSLPGR 195 A GAG G +G S AD V A+ A AAAA +GP S V Sbjct: 547 PAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRV------- 599 Query: 196 ANPAARHPNL 205 PA HP+L Sbjct: 600 --PAPHHPHL 607 Score = 29.3 bits (64), Expect = 7.5 Identities = 24/84 (28%), Positives = 33/84 (39%), Gaps = 2/84 (2%) Query: 8 AANHGPPPGAYEAGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAGSASGGAS 67 +A PP + A G GA G+G A S VP P P + G G S++ Sbjct: 570 SAGSTPPADSVAAAGAGAAAAGSGPAGS--RVPAPHHPHLLEGRKAGGGSYHHSSAFRPV 627 Query: 68 GGSSGGAASGAGPGTQQGSPGWSQ 91 GG + G G+P +Q Sbjct: 628 GGKDDAESLAKLHGASAGAPHSAQ 651 >gi|239746067 PREDICTED: functional smad suppressing element 18 [Homo sapiens] Length = 1252 Score = 50.4 bits (119), Expect = 3e-06 Identities = 56/171 (32%), Positives = 70/171 (40%), Gaps = 33/171 (19%) Query: 13 PPPGAYEAGGPGA------FMHGAGAASSPVYVPTPRVPSSVLGLSYLQG-GGAGSASGG 65 PPP A AG P A F + V + ++ LS GGAG+ GG Sbjct: 292 PPPLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGGG 351 Query: 66 ASGGSSGGAASGAGPGTQQGSPGWSQAGADG-AAYTPPPVSPRFS-------FPGTTG-- 115 A GG G GAG G G AGA G +Y PV + S FPG G Sbjct: 352 AGGGCVAGVGVGAGAGAGAG------AGAKGPRSYPVIPVPSKGSFGGVLQKFPGCGGLF 405 Query: 116 ----SLAAAAAAAA----AREAAAYSSGGGAAGAGLAGREQYGRAGFAGSY 158 + AAAAA + +A A + G AGAG AG +AG +G + Sbjct: 406 PHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAGAGGAGAAP--KAGLSGLF 454 Score = 41.6 bits (96), Expect = 0.001 Identities = 49/178 (27%), Positives = 58/178 (32%), Gaps = 19/178 (10%) Query: 31 GAASSPVYVPTPRVPSSVLGLSYLQ---------------GGGAGSASGGASGGSSGGAA 75 G P Y+ P P S LG + + GG AGSA G Sbjct: 477 GGLPVPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVV 536 Query: 76 SGAGPGTQQGSPGWSQAGADGAAYTPPPVSPRFSFPGTTGSLAAAAAAAAAREAAAYSSG 135 + GPG+ P D +PP S G+T + AAA A AA Sbjct: 537 AN-GPGSGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPA 595 Query: 136 GGAAGAGLAGREQYGRAGFAGSY---SSPYPAYMADVGASWAAAAAASAGPFDSPVLH 190 G A GR GSY S+ P D S A ASAG S H Sbjct: 596 GSRVPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGAPHSAQTH 653 Score = 32.0 bits (71), Expect = 1.2 Identities = 52/190 (27%), Positives = 63/190 (33%), Gaps = 56/190 (29%) Query: 63 SGGASGGSSGGAASGAGPGTQQGSPG-WSQAGADGAAYTP-----PPVSP---------- 106 +G A+ G A GAG + G G + AG A Y P PP +P Sbjct: 427 AGAAAEALGGAGAGGAGAAPKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLPVPTYLQ 486 Query: 107 --------------------RFSF------PGTTGSLAAAAAAAAAREAAAYSSGGG--- 137 R +F G GS AA + A G G Sbjct: 487 PPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGPGSGPPP 546 Query: 138 -AAGAGLAGREQYGRAGFAGSYSSPYPAYMAD-VGASWAAAAAASAGPFDSPVLHSLPGR 195 A GAG G +G S AD V A+ A AAAA +GP S V Sbjct: 547 PAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRV------- 599 Query: 196 ANPAARHPNL 205 PA HP+L Sbjct: 600 --PAPHHPHL 607 Score = 29.3 bits (64), Expect = 7.5 Identities = 24/84 (28%), Positives = 33/84 (39%), Gaps = 2/84 (2%) Query: 8 AANHGPPPGAYEAGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAGSASGGAS 67 +A PP + A G GA G+G A S VP P P + G G S++ Sbjct: 570 SAGSTPPADSVAAAGAGAAAAGSGPAGS--RVPAPHHPHLLEGRKAGGGSYHHSSAFRPV 627 Query: 68 GGSSGGAASGAGPGTQQGSPGWSQ 91 GG + G G+P +Q Sbjct: 628 GGKDDAESLAKLHGASAGAPHSAQ 651 >gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] Length = 2968 Score = 49.7 bits (117), Expect = 5e-06 Identities = 43/190 (22%), Positives = 80/190 (42%), Gaps = 10/190 (5%) Query: 22 GPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAGSASGGASGGSSGGAASGAGPG 81 GPG +G SP + + S +GS+S +S SSG G G Sbjct: 2530 GPGLTFEDSGNPKSPDKAQAEQDGAEESESS--SSSSSGSSSSSSSSSSSGSETEGEEEG 2587 Query: 82 TQQGSPGWSQAGADGAAYTPPPVSPRFSFPGTTGSLAAAAAAAAAREAAAYSSGGGAAGA 141 + G G G + +A + SP S ++ S +++++++++ +++ SS ++ + Sbjct: 2588 DKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2647 Query: 142 GLAGREQYGRAGFAGSYSSPYPAYMADVGASWA----AAAAASAGPFDSPVLHS----LP 193 + + + S SS + D +S + AA A +AGP L + Sbjct: 2648 SSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQA 2707 Query: 194 GRANPAARHP 203 G+A P+A P Sbjct: 2708 GKARPSAHSP 2717 Score = 40.8 bits (94), Expect = 0.002 Identities = 32/111 (28%), Positives = 48/111 (43%), Gaps = 9/111 (8%) Query: 317 TRKRKPKNLNKSKTPAAPSGSESLPPASGASSNSSNATTSSSEEMRPIKTEPGLSSHYGH 376 +R P + + S + ++ S S S +S +SS+SS++++SSS + SS Sbjct: 2607 SRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2666 Query: 377 SSSVSQTFSVSAMSGH---------GPSIHPVLSALKLSPQGYASPVSQSP 418 SSS S T S+ S GPS L G A P + SP Sbjct: 2667 SSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSP 2717 Score = 30.4 bits (67), Expect = 3.4 Identities = 31/115 (26%), Positives = 50/115 (43%), Gaps = 9/115 (7%) Query: 322 PKNLNKSKTPAAPSGSESLPPASGASSNSSNATTSSSE-------EMRPIKTEPGLSSHY 374 PK+ +K++ A G+E +S +SS SS++++SSS E K G Sbjct: 2541 PKSPDKAQ--AEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTG 2598 Query: 375 GHSSSVSQTFSVSAMSGHGPSIHPVLSALKLSPQGYASPVSQSPQTSSKQDSWNS 429 G + S + + + S S S S+ S +S S S +SS S +S Sbjct: 2599 GRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2653 Score = 30.4 bits (67), Expect = 3.4 Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 12/91 (13%) Query: 335 SGSESLPPASGASSNSSNATTSSSEEMRPIKTEPGLSSHYGHSSSVSQTFSVSAMSGHGP 394 + S + PAS +SS+SS++++SSS SS SSS S + S S+ S Sbjct: 2605 ASSRAASPASSSSSSSSSSSSSSS------------SSSSSSSSSSSSSSSSSSSSSSSS 2652 Query: 395 SIHPVLSALKLSPQGYASPVSQSPQTSSKQD 425 S S+ S +S + + S D Sbjct: 2653 SSSSSSSSSSSSSSSSSSSTTDEDSSCSSDD 2683 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 48.5 bits (114), Expect = 1e-05 Identities = 58/192 (30%), Positives = 66/192 (34%), Gaps = 30/192 (15%) Query: 14 PPGAYEAGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQG--GGAGSASGGASGGSS 71 PPG E GGPG+ G A V P+ P+ G G G G A G Sbjct: 483 PPG--ERGGPGS--RGFPGADG---VAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLP 535 Query: 72 G-----GAASGAGPGTQQGSPGWSQAGADGAAYTPPPVSPRFSFPGTTGSLAAAAAAAAA 126 G G+ GP + G PG AG DG P P R G G + AA Sbjct: 536 GAKGLTGSPGSPGPDGKTGPPG--PAGQDGRPGPPGPPGAR----GQAGVMGFPGPKGAA 589 Query: 127 REAAAYSSGGGAAGAGLAGREQYGRAGFAGSYSSPYPAYMADVGASWAAAAAASAGPFDS 186 E G G G G+ G AG+ P PA A GP S Sbjct: 590 GEPGKAGERGVPGPPGAVGPA--GKDGEAGAQGPPGPA--------GPAGERGEQGPAGS 639 Query: 187 PVLHSLPGRANP 198 P LPG A P Sbjct: 640 PGFQGLPGPAGP 651 Score = 42.7 bits (99), Expect = 7e-04 Identities = 64/234 (27%), Positives = 73/234 (31%), Gaps = 57/234 (24%) Query: 12 GPPPGAYEAGGPGAFMHGAGAASSP-----------VYVPTPRVPSSVLGLSYLQGGGAG 60 GPP A E G PGA AGA +P V +P R GL G Sbjct: 926 GPPGPAGEKGSPGAD-GPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGK 984 Query: 61 SASGGASG-----------------GSSG--GAASGAGPGTQQGSPGWS----------Q 91 GASG G SG GA G + GSPG Sbjct: 985 QGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGP 1044 Query: 92 AGADGAAYTPPPVSPRFSFPGTTGSLAAAAAAAAAREAAAYSSGGGAAGAGLAG------ 145 GA GA P PV P G +G A A + G A G G Sbjct: 1045 PGAPGAPGAPGPVGP----AGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETG 1100 Query: 146 ----REQYGRAGFAGSYSSPYPAYMADVGASWAAAAAASAGPFDSPVLHSLPGR 195 R G GF+G P P G + A+ AGP P PG+ Sbjct: 1101 EQGDRGIKGHRGFSGLQGPPGPP--GSPGEQGPSGASGPAGPRGPPGSAGAPGK 1152 Score = 40.4 bits (93), Expect = 0.003 Identities = 61/209 (29%), Positives = 70/209 (33%), Gaps = 35/209 (16%) Query: 12 GPP-----PGAY-EAGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAGSASGG 65 GPP PGA E G GA G P P P +G +G + G Sbjct: 815 GPPGADGQPGAKGEPGDAGA--KGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPG 872 Query: 66 ASG-----------GSSGGAASGAGPGTQQGSPGWSQAGADGAAYTPPPVSPRFSFPGTT 114 A+G G SG A PG G G G A P V P PG Sbjct: 873 ATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGP----PGPP 928 Query: 115 GSLAAAAAAAAAREAAAYSSGG--GAAG----AGLAGREQYGRAGFAGSYSSPYPA-YMA 167 G + A A A + G G AG GL G Q G GF G P P+ Sbjct: 929 GPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPG--QRGERGFPG---LPGPSGEPG 983 Query: 168 DVGASWAAAAAASAGPFDSPVLHSLPGRA 196 G S A+ GP P L PG + Sbjct: 984 KQGPSGASGERGPPGPMGPPGLAGPPGES 1012 Score = 39.7 bits (91), Expect = 0.006 Identities = 56/202 (27%), Positives = 68/202 (33%), Gaps = 29/202 (14%) Query: 12 GPPPGAYEAGGPGAFMH-GAGAASSPVYVPTPRVPSSVLGLSYLQGGGAGSASGGASGGS 70 GP + E G PG+ GA PV V P P+ + G G+ G Sbjct: 428 GPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAG-------EEGKRGARGEPGPTGL 480 Query: 71 SGGAASGAGPGTQQGSPGWSQAGADGAAYTPPPVSPRFSFPGTTGSLAAAAAAAAAREAA 130 G GPG++ G PG ADG A P R S PG G + A EA Sbjct: 481 PGPPGERGGPGSR-GFPG-----ADGVAGPKGPAGERGS-PGPAGPKGSPGEAGRPGEAG 533 Query: 131 AYSSGGGAAGAGLAGRE-QYGRAGFAGSYSSPYP----------AYMADVGASWAAAAAA 179 + G G G + + G G AG P P M G AA Sbjct: 534 LPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPG 593 Query: 180 SAGPFDSPVLHSLPGRANPAAR 201 AG P PG PA + Sbjct: 594 KAGERGVP---GPPGAVGPAGK 612 Score = 38.5 bits (88), Expect = 0.012 Identities = 55/192 (28%), Positives = 67/192 (34%), Gaps = 32/192 (16%) Query: 14 PPGAY----EAGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAGSASGGASGG 69 PPG EAG PG G P +P + GL ++G S GA G Sbjct: 225 PPGKNGDDGEAGKPGR----PGERGPPGPQGARGLPGTA-GLPGMKGHRGFSGLDGAKGD 279 Query: 70 SSGGAASGAGPGTQQGSPGWSQAGADGAAYTPPPVSPRFSFPGTTGSLAAAAAAAAAREA 129 A AGP + GSPG + A P + PR PG G A A A Sbjct: 280 -----AGPAGPKGEPGSPGENGA--------PGQMGPR-GLPGERGRPGAPGPAGARGND 325 Query: 130 AAYSSGGGAAGAGLAGREQY-------GRAGFAGSYSSPYPAYMADVGASWAAAAAASAG 182 A + G G AG + G AG G S P + G A +AG Sbjct: 326 GATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVR--GEPGPPGPAGAAG 383 Query: 183 PFDSPVLHSLPG 194 P +P PG Sbjct: 384 PAGNPGADGQPG 395 Score = 37.7 bits (86), Expect = 0.021 Identities = 66/238 (27%), Positives = 79/238 (33%), Gaps = 56/238 (23%) Query: 14 PPGAYEAGGPGAF-MHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAGSASGGASG--GS 70 PPG EAG PG + G A P R G+ G + GA G G+ Sbjct: 651 PPG--EAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGA 708 Query: 71 SGGAASGAGPGTQQGSPGWS-QAGADGAAYTPPPVSPR--------------FSFPGTTG 115 G A + PG+Q G+PG G GAA P P R G TG Sbjct: 709 KGDAGAPGAPGSQ-GAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTG 767 Query: 116 SLAAAAAAAAAREAAAYSSGG-----GAAG-------------AGLAG----------RE 147 + A A + G GA G AG AG + Sbjct: 768 PIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKG 827 Query: 148 QYGRAGFAGSYSSPYPAYMA-------DVGASWAAAAAASAGPFDSPVLHSLPGRANP 198 + G AG G P PA A +VGA A A SAGP + GR P Sbjct: 828 EPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGP 885 Score = 36.6 bits (83), Expect = 0.047 Identities = 47/163 (28%), Positives = 51/163 (31%), Gaps = 17/163 (10%) Query: 14 PPGAYEAGGPGAFMHGAGAASSPVY-----VPTPRV---PSSVLGLSYLQG-----GGAG 60 PPGA G F GAA P VP P P+ G + QG G AG Sbjct: 570 PPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAG 629 Query: 61 SASGGASGGSSG--GAASGAGPGTQQGSPGWSQAGADGAAYTPPPVSPRFSFPGTTGSLA 118 GS G G AGP + G PG D A P FPG G Sbjct: 630 ERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQG 689 Query: 119 AAAAAAAAREAAAYSSGGGAAGAGLAGREQYGRAGFAGSYSSP 161 A A + G AG G G G G P Sbjct: 690 PPGPAGPRGANGAPGNDGAKGDAGAPGAP--GSQGAPGLQGMP 730 Score = 32.3 bits (72), Expect = 0.88 Identities = 56/203 (27%), Positives = 63/203 (31%), Gaps = 27/203 (13%) Query: 12 GPPPGAYEAGGPG-AFMHGAGAASSPVYVPTPRVPSSVLGLSYLQG--GGAGSASGGASG 68 G P G PG A G A+ P P P+ G G G AG S Sbjct: 305 GLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSE 364 Query: 69 GSSG--------GAASGAGPGTQQGSPGW-SQAGADGAAYTPPPVSPRFSFPGTTGSLAA 119 G G G A AGP G+PG Q GA G A P ++ FPG G Sbjct: 365 GPQGVRGEPGPPGPAGAAGP---AGNPGADGQPGAKG-ANGAPGIAGAPGFPGARGPSGP 420 Query: 120 AAAAAAAREAAAYSSGGGAAGAGLAGREQYGRAGFAGSYSSPYPAYMADVGASWAAAAAA 179 G G G + G G G P PA G A Sbjct: 421 QGPGGPPGPKGNSGEPGAPGSKGDTGAK--GEPGPVGVQGPPGPA-----GEEGKRGARG 473 Query: 180 SAGPFDSPVLHSLPG-RANPAAR 201 GP P PG R P +R Sbjct: 474 EPGPTGLP---GPPGERGGPGSR 493 >gi|119395716 forkhead box C1 [Homo sapiens] Length = 553 Score = 48.5 bits (114), Expect = 1e-05 Identities = 62/205 (30%), Positives = 79/205 (38%), Gaps = 34/205 (16%) Query: 3 QSLAMAANHGPPPGAYEAGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGAGSA 62 QS A + G A + G A A SP P S + GGG G A Sbjct: 322 QSAAAELSSGLLASAAASSRAGIAPPLALGAYSPGQSSLYSSPCSQTSSAGSSGGGGGGA 381 Query: 63 SGGASGGSSGGA------------ASGAGPGTQQGSPGWSQAGADGAAYTPPPVSPRFSF 110 GA+GG+ G A+G G QG+PG GA G+A P P +S Sbjct: 382 --GAAGGAGGAGTYHCNLQAMSLYAAGERGGHLQGAPG----GAGGSAVDDP--LPDYSL 433 Query: 111 PGTTGSLAAAAAAAAAREAAAYSSGGGAAGAGLAGREQYGRAGFAGSYSSPYPAYM-ADV 169 P T S +++ S GGG G G + A G +S Y D+ Sbjct: 434 PPVTSS-----------SSSSLSHGGGGGGGGGGQEAGHHPAAHQGRLTSWYLNQAGGDL 482 Query: 170 G--ASWAAAAAASAGPFDSPVLHSL 192 G AS AAAAAA+ P HS+ Sbjct: 483 GHLASAAAAAAAAGYPGQQQNFHSV 507 Score = 37.7 bits (86), Expect = 0.021 Identities = 48/168 (28%), Positives = 61/168 (36%), Gaps = 26/168 (15%) Query: 31 GAASSPVYVPTPRVPSSVLGLSYLQGGGAGSASGGASGGSSGGAASGAGPGTQQGS-PGW 89 G SP P P P++ LG G A + SS +SG+ P GS P Sbjct: 231 GTCPSP---PQPLSPAAALG----SGSAAAVPKIESPDSSSSSLSSGSSP---PGSLPSA 280 Query: 90 SQAGADGAAYTPPPVSPR---------FSFPGTTGSLAAAAAAAAAR------EAAAYSS 134 DGA PPP +P FS SL + +AAA +AA SS Sbjct: 281 RPLSLDGADSAPPPPAPSAPPPHHSQGFSVDNIMTSLRGSPQSAAAELSSGLLASAAASS 340 Query: 135 GGGAAGAGLAGREQYGRAGFAGSYSSPYPAYMADVGASWAAAAAASAG 182 G A G G++ S S + + G A AA AG Sbjct: 341 RAGIAPPLALGAYSPGQSSLYSSPCSQTSSAGSSGGGGGGAGAAGGAG 388 Score = 37.4 bits (85), Expect = 0.027 Identities = 43/149 (28%), Positives = 62/149 (41%), Gaps = 32/149 (21%) Query: 14 PPGAYEAGGPGAFMHGAGAASSPVYVPTPRVP----SSVLGLSYLQGGGAGSASGGASGG 69 PPG+ + P + + GA +A P P P P S + + GS A+ Sbjct: 273 PPGSLPSARPLS-LDGADSAPPP---PAPSAPPPHHSQGFSVDNIMTSLRGSPQSAAAEL 328 Query: 70 SSGGAASGAGPGTQQGSPGWSQAGADGAAYTPPPVSPRFSFPGTTGSLAAAAAAAAAREA 129 SSG AS A A A PP++ PG + + ++ ++ + Sbjct: 329 SSGLLASAA---------------ASSRAGIAPPLALGAYSPGQS----SLYSSPCSQTS 369 Query: 130 AAYSSGGGAAGAGLAGREQYGRAGFAGSY 158 +A SSGGG GAG A G AG AG+Y Sbjct: 370 SAGSSGGGGGGAGAA-----GGAGGAGTY 393 Score = 29.6 bits (65), Expect = 5.7 Identities = 30/125 (24%), Positives = 52/125 (41%), Gaps = 3/125 (2%) Query: 305 PRPLAMRKEGIQTRKRKPKNLNKSKTPAAPSGSESLPPASGASSNSSNATTSSSEEMRPI 364 P+P +R + I+T + + +PAA GS S S S++++ SS P Sbjct: 216 PQPPPVRIQDIKTENGTCPSPPQPLSPAAALGSGSAAAVPKIESPDSSSSSLSSGSSPPG 275 Query: 365 KTEPGLSSHYGHSSSVSQTFSVSAMSGH---GPSIHPVLSALKLSPQGYASPVSQSPQTS 421 + S + SA H G S+ ++++L+ SPQ A+ +S S Sbjct: 276 SLPSARPLSLDGADSAPPPPAPSAPPPHHSQGFSVDNIMTSLRGSPQSAAAELSSGLLAS 335 Query: 422 SKQDS 426 + S Sbjct: 336 AAASS 340 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.126 0.383 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 21,885,856 Number of Sequences: 37866 Number of extensions: 1316304 Number of successful extensions: 21994 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 460 Number of HSP's successfully gapped in prelim test: 955 Number of HSP's that attempted gapping in prelim test: 10015 Number of HSP's gapped (non-prelim): 6347 length of query: 442 length of database: 18,247,518 effective HSP length: 105 effective length of query: 337 effective length of database: 14,271,588 effective search space: 4809525156 effective search space used: 4809525156 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.