BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens] (1528 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens] 3064 0.0 gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens] 2168 0.0 gi|41281907 StAR-related lipid transfer (START) domain containin... 1102 0.0 gi|41281898 StAR-related lipid transfer (START) domain containin... 1101 0.0 gi|16445031 StAR-related lipid transfer (START) domain containin... 999 0.0 gi|33188435 deleted in liver cancer 1 isoform 3 [Homo sapiens] 898 0.0 gi|215820652 StAR-related lipid transfer (START) domain containi... 653 0.0 gi|215820650 StAR-related lipid transfer (START) domain containi... 653 0.0 gi|31543659 StAR-related lipid transfer (START) domain containin... 653 0.0 gi|39932589 Rho GTPase activating protein 18 [Homo sapiens] 99 2e-20 gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens] 92 5e-18 gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo sapi... 92 5e-18 gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo sapi... 92 5e-18 gi|239757488 PREDICTED: chromosome 20 open reading frame 95 [Hom... 88 6e-17 gi|239752003 PREDICTED: chromosome 20 open reading frame 95 [Hom... 88 6e-17 gi|239746488 PREDICTED: Rho GTPase-activating protein 18-like [H... 88 6e-17 gi|54860079 nadrin isoform 1 [Homo sapiens] 88 6e-17 gi|54860105 nadrin isoform 2 [Homo sapiens] 88 6e-17 gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens] 85 6e-16 gi|59710113 Rho GTPase activating protein 28 isoform a [Homo sap... 84 1e-15 gi|59710111 Rho GTPase activating protein 28 isoform b [Homo sap... 84 1e-15 gi|40255080 hypothetical protein LOC158763 [Homo sapiens] 83 2e-15 gi|85815829 SH3-domain binding protein 1 [Homo sapiens] 83 2e-15 gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens] 83 2e-15 gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo ... 82 4e-15 gi|5803145 ralA binding protein 1 [Homo sapiens] 82 4e-15 gi|194272142 myosin IXB isoform 2 [Homo sapiens] 82 4e-15 gi|33356170 myosin IXB isoform 1 [Homo sapiens] 82 4e-15 gi|156071465 Rho GTPase activating protein 4 [Homo sapiens] 82 5e-15 gi|26986534 Rho GTPase activating protein 12 [Homo sapiens] 79 3e-14 >gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens] Length = 1528 Score = 3064 bits (7943), Expect = 0.0 Identities = 1528/1528 (100%), Positives = 1528/1528 (100%) Query: 1 MSVAIRKRSWEEHVTHWMGQPFNSDDRNTACHHGLVADSLQASMEKDATLNVDRKEKCVS 60 MSVAIRKRSWEEHVTHWMGQPFNSDDRNTACHHGLVADSLQASMEKDATLNVDRKEKCVS Sbjct: 1 MSVAIRKRSWEEHVTHWMGQPFNSDDRNTACHHGLVADSLQASMEKDATLNVDRKEKCVS 60 Query: 61 LPDCCHGSELRDFPGRPMGHLSKDVDENDSHEGEDQFLSLEASTETLVHVSDEDNNADLC 120 LPDCCHGSELRDFPGRPMGHLSKDVDENDSHEGEDQFLSLEASTETLVHVSDEDNNADLC Sbjct: 61 LPDCCHGSELRDFPGRPMGHLSKDVDENDSHEGEDQFLSLEASTETLVHVSDEDNNADLC 120 Query: 121 LTDDKQVLNTQGQKTSGQHMIQGAGSLEKALPIIQSNQVSSNSWGIAGETELALVKESGE 180 LTDDKQVLNTQGQKTSGQHMIQGAGSLEKALPIIQSNQVSSNSWGIAGETELALVKESGE Sbjct: 121 LTDDKQVLNTQGQKTSGQHMIQGAGSLEKALPIIQSNQVSSNSWGIAGETELALVKESGE 180 Query: 181 RKVTDSISKSLELCNEISLSEIKDAPKVNAVDTLNVKDIAPEKQLLNSAVIAQQRRKPDP 240 RKVTDSISKSLELCNEISLSEIKDAPKVNAVDTLNVKDIAPEKQLLNSAVIAQQRRKPDP Sbjct: 181 RKVTDSISKSLELCNEISLSEIKDAPKVNAVDTLNVKDIAPEKQLLNSAVIAQQRRKPDP 240 Query: 241 PKDENERSTCNVVQDEFLDTPCTNRGLPLLKTDFGSCLLQPPSCPNGMSAENGLEKSGFS 300 PKDENERSTCNVVQDEFLDTPCTNRGLPLLKTDFGSCLLQPPSCPNGMSAENGLEKSGFS Sbjct: 241 PKDENERSTCNVVQDEFLDTPCTNRGLPLLKTDFGSCLLQPPSCPNGMSAENGLEKSGFS 300 Query: 301 QHQNKSPPKVKAEDGMQCLQLKETLATQEPTDNQVRLRKRKEIREDRDRARLDSMVLLIM 360 QHQNKSPPKVKAEDGMQCLQLKETLATQEPTDNQVRLRKRKEIREDRDRARLDSMVLLIM Sbjct: 301 QHQNKSPPKVKAEDGMQCLQLKETLATQEPTDNQVRLRKRKEIREDRDRARLDSMVLLIM 360 Query: 361 KLDQLDQDIENALSTSSSPSGTPTNLRRHVPDLESGSESGADTISVNQTRVNLSSDTEST 420 KLDQLDQDIENALSTSSSPSGTPTNLRRHVPDLESGSESGADTISVNQTRVNLSSDTEST Sbjct: 361 KLDQLDQDIENALSTSSSPSGTPTNLRRHVPDLESGSESGADTISVNQTRVNLSSDTEST 420 Query: 421 DLPSSTPVANSGTKPKTTAIQGISEKEKAEIEAKEACDWLRATGFPQYAQLYEDFLFPID 480 DLPSSTPVANSGTKPKTTAIQGISEKEKAEIEAKEACDWLRATGFPQYAQLYEDFLFPID Sbjct: 421 DLPSSTPVANSGTKPKTTAIQGISEKEKAEIEAKEACDWLRATGFPQYAQLYEDFLFPID 480 Query: 481 ISLVKREHDFLDRDAIEALCRRLNTLNKCAVMKLEISPHRKRSDDSDEDEPCAISGKWTF 540 ISLVKREHDFLDRDAIEALCRRLNTLNKCAVMKLEISPHRKRSDDSDEDEPCAISGKWTF Sbjct: 481 ISLVKREHDFLDRDAIEALCRRLNTLNKCAVMKLEISPHRKRSDDSDEDEPCAISGKWTF 540 Query: 541 QRDSKRWSRLEEFDVFSPKQDLVPGSPDDSHPKDGPSPGGTLMDLSERQEVSSVRSLSST 600 QRDSKRWSRLEEFDVFSPKQDLVPGSPDDSHPKDGPSPGGTLMDLSERQEVSSVRSLSST Sbjct: 541 QRDSKRWSRLEEFDVFSPKQDLVPGSPDDSHPKDGPSPGGTLMDLSERQEVSSVRSLSST 600 Query: 601 GSLPSHAPPSEDAATPRTNSVISVCSSSNLAGNDDSFGSLPSPKELSSFSFSMKGHEKTA 660 GSLPSHAPPSEDAATPRTNSVISVCSSSNLAGNDDSFGSLPSPKELSSFSFSMKGHEKTA Sbjct: 601 GSLPSHAPPSEDAATPRTNSVISVCSSSNLAGNDDSFGSLPSPKELSSFSFSMKGHEKTA 660 Query: 661 KSKTRSLLKRMESLKLKSSHHSKHKAPSKLGLIISGPILQEGMDEEKLKQLNCVEISALN 720 KSKTRSLLKRMESLKLKSSHHSKHKAPSKLGLIISGPILQEGMDEEKLKQLNCVEISALN Sbjct: 661 KSKTRSLLKRMESLKLKSSHHSKHKAPSKLGLIISGPILQEGMDEEKLKQLNCVEISALN 720 Query: 721 GNRINVPMVRKRSVSNSTQTSSSSSQSETSSAVSTPSPVTRTRSLSACNKRVGMYLEGFD 780 GNRINVPMVRKRSVSNSTQTSSSSSQSETSSAVSTPSPVTRTRSLSACNKRVGMYLEGFD Sbjct: 721 GNRINVPMVRKRSVSNSTQTSSSSSQSETSSAVSTPSPVTRTRSLSACNKRVGMYLEGFD 780 Query: 781 PFNQSTFNNVVEQNFKNRESYPEDTVFYIPEDHKPGTFPKALTNGSFSPSGNNGSVNWRT 840 PFNQSTFNNVVEQNFKNRESYPEDTVFYIPEDHKPGTFPKALTNGSFSPSGNNGSVNWRT Sbjct: 781 PFNQSTFNNVVEQNFKNRESYPEDTVFYIPEDHKPGTFPKALTNGSFSPSGNNGSVNWRT 840 Query: 841 GSFHGPGHISLRRENSSDSPKELKRRNSSSSMSSRLSIYDNVPGSILYSSSGDLADLENE 900 GSFHGPGHISLRRENSSDSPKELKRRNSSSSMSSRLSIYDNVPGSILYSSSGDLADLENE Sbjct: 841 GSFHGPGHISLRRENSSDSPKELKRRNSSSSMSSRLSIYDNVPGSILYSSSGDLADLENE 900 Query: 901 DIFPELDDILYHVKGMQRIVNQWSEKFSDEGDSDSALDSVSPCPSSPKQIHLDVDNDRTT 960 DIFPELDDILYHVKGMQRIVNQWSEKFSDEGDSDSALDSVSPCPSSPKQIHLDVDNDRTT Sbjct: 901 DIFPELDDILYHVKGMQRIVNQWSEKFSDEGDSDSALDSVSPCPSSPKQIHLDVDNDRTT 960 Query: 961 PSDLDSTGNSLNEPEEPSEIPERRDSGVGASLTRSNRHRLRWHSFQSSHRPSLNSVSLQI 1020 PSDLDSTGNSLNEPEEPSEIPERRDSGVGASLTRSNRHRLRWHSFQSSHRPSLNSVSLQI Sbjct: 961 PSDLDSTGNSLNEPEEPSEIPERRDSGVGASLTRSNRHRLRWHSFQSSHRPSLNSVSLQI 1020 Query: 1021 NCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPL 1080 NCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPL Sbjct: 1021 NCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPL 1080 Query: 1081 TVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEG 1140 TVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEG Sbjct: 1081 TVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEG 1140 Query: 1141 QSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREV 1200 QSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREV Sbjct: 1141 QSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREV 1200 Query: 1201 LQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQ 1260 LQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQ Sbjct: 1201 LQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQ 1260 Query: 1261 KDLNENLAATQGLAHMIAECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGHLGNDDSAD 1320 KDLNENLAATQGLAHMIAECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGHLGNDDSAD Sbjct: 1261 KDLNENLAATQGLAHMIAECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGHLGNDDSAD 1320 Query: 1321 YQHFLQDCVDGLFKEVKEKFKGWVSYSTSEQAELSYKKVSEGPPLRLWRSVIEVPAVPEE 1380 YQHFLQDCVDGLFKEVKEKFKGWVSYSTSEQAELSYKKVSEGPPLRLWRSVIEVPAVPEE Sbjct: 1321 YQHFLQDCVDGLFKEVKEKFKGWVSYSTSEQAELSYKKVSEGPPLRLWRSVIEVPAVPEE 1380 Query: 1381 ILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPKG 1440 ILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPKG Sbjct: 1381 ILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPKG 1440 Query: 1441 ACALLLTSVDHDRAPVVGVRVNVLLSRYLIEPCGPGKSKLTYMCRVDLRGHMPEWYTKSF 1500 ACALLLTSVDHDRAPVVGVRVNVLLSRYLIEPCGPGKSKLTYMCRVDLRGHMPEWYTKSF Sbjct: 1441 ACALLLTSVDHDRAPVVGVRVNVLLSRYLIEPCGPGKSKLTYMCRVDLRGHMPEWYTKSF 1500 Query: 1501 GHLCAAEVVKIRDSFSNQNTETKDTKSR 1528 GHLCAAEVVKIRDSFSNQNTETKDTKSR Sbjct: 1501 GHLCAAEVVKIRDSFSNQNTETKDTKSR 1528 >gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens] Length = 1091 Score = 2168 bits (5618), Expect = 0.0 Identities = 1078/1079 (99%), Positives = 1079/1079 (100%) Query: 450 EIEAKEACDWLRATGFPQYAQLYEDFLFPIDISLVKREHDFLDRDAIEALCRRLNTLNKC 509 +IEAKEACDWLRATGFPQYAQLYEDFLFPIDISLVKREHDFLDRDAIEALCRRLNTLNKC Sbjct: 13 QIEAKEACDWLRATGFPQYAQLYEDFLFPIDISLVKREHDFLDRDAIEALCRRLNTLNKC 72 Query: 510 AVMKLEISPHRKRSDDSDEDEPCAISGKWTFQRDSKRWSRLEEFDVFSPKQDLVPGSPDD 569 AVMKLEISPHRKRSDDSDEDEPCAISGKWTFQRDSKRWSRLEEFDVFSPKQDLVPGSPDD Sbjct: 73 AVMKLEISPHRKRSDDSDEDEPCAISGKWTFQRDSKRWSRLEEFDVFSPKQDLVPGSPDD 132 Query: 570 SHPKDGPSPGGTLMDLSERQEVSSVRSLSSTGSLPSHAPPSEDAATPRTNSVISVCSSSN 629 SHPKDGPSPGGTLMDLSERQEVSSVRSLSSTGSLPSHAPPSEDAATPRTNSVISVCSSSN Sbjct: 133 SHPKDGPSPGGTLMDLSERQEVSSVRSLSSTGSLPSHAPPSEDAATPRTNSVISVCSSSN 192 Query: 630 LAGNDDSFGSLPSPKELSSFSFSMKGHEKTAKSKTRSLLKRMESLKLKSSHHSKHKAPSK 689 LAGNDDSFGSLPSPKELSSFSFSMKGHEKTAKSKTRSLLKRMESLKLKSSHHSKHKAPSK Sbjct: 193 LAGNDDSFGSLPSPKELSSFSFSMKGHEKTAKSKTRSLLKRMESLKLKSSHHSKHKAPSK 252 Query: 690 LGLIISGPILQEGMDEEKLKQLNCVEISALNGNRINVPMVRKRSVSNSTQTSSSSSQSET 749 LGLIISGPILQEGMDEEKLKQLNCVEISALNGNRINVPMVRKRSVSNSTQTSSSSSQSET Sbjct: 253 LGLIISGPILQEGMDEEKLKQLNCVEISALNGNRINVPMVRKRSVSNSTQTSSSSSQSET 312 Query: 750 SSAVSTPSPVTRTRSLSACNKRVGMYLEGFDPFNQSTFNNVVEQNFKNRESYPEDTVFYI 809 SSAVSTPSPVTRTRSLSACNKRVGMYLEGFDPFNQSTFNNVVEQNFKNRESYPEDTVFYI Sbjct: 313 SSAVSTPSPVTRTRSLSACNKRVGMYLEGFDPFNQSTFNNVVEQNFKNRESYPEDTVFYI 372 Query: 810 PEDHKPGTFPKALTNGSFSPSGNNGSVNWRTGSFHGPGHISLRRENSSDSPKELKRRNSS 869 PEDHKPGTFPKALTNGSFSPSGNNGSVNWRTGSFHGPGHISLRRENSSDSPKELKRRNSS Sbjct: 373 PEDHKPGTFPKALTNGSFSPSGNNGSVNWRTGSFHGPGHISLRRENSSDSPKELKRRNSS 432 Query: 870 SSMSSRLSIYDNVPGSILYSSSGDLADLENEDIFPELDDILYHVKGMQRIVNQWSEKFSD 929 SSMSSRLSIYDNVPGSILYSSSGDLADLENEDIFPELDDILYHVKGMQRIVNQWSEKFSD Sbjct: 433 SSMSSRLSIYDNVPGSILYSSSGDLADLENEDIFPELDDILYHVKGMQRIVNQWSEKFSD 492 Query: 930 EGDSDSALDSVSPCPSSPKQIHLDVDNDRTTPSDLDSTGNSLNEPEEPSEIPERRDSGVG 989 EGDSDSALDSVSPCPSSPKQIHLDVDNDRTTPSDLDSTGNSLNEPEEPSEIPERRDSGVG Sbjct: 493 EGDSDSALDSVSPCPSSPKQIHLDVDNDRTTPSDLDSTGNSLNEPEEPSEIPERRDSGVG 552 Query: 990 ASLTRSNRHRLRWHSFQSSHRPSLNSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPS 1049 ASLTRSNRHRLRWHSFQSSHRPSLNSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPS Sbjct: 553 ASLTRSNRHRLRWHSFQSSHRPSLNSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPS 612 Query: 1050 NKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQ 1109 NKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQ Sbjct: 613 NKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQ 672 Query: 1110 VGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSET 1169 VGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSET Sbjct: 673 VGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSET 732 Query: 1170 FLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCL 1229 FLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCL Sbjct: 733 FLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCL 792 Query: 1230 APSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEE 1289 APSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEE Sbjct: 793 APSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEE 852 Query: 1290 MSRCRNSYTEQELKPLTLEALGHLGNDDSADYQHFLQDCVDGLFKEVKEKFKGWVSYSTS 1349 MSRCRNSYTEQELKPLTLEALGHLGNDDSADYQHFLQDCVDGLFKEVKEKFKGWVSYSTS Sbjct: 853 MSRCRNSYTEQELKPLTLEALGHLGNDDSADYQHFLQDCVDGLFKEVKEKFKGWVSYSTS 912 Query: 1350 EQAELSYKKVSEGPPLRLWRSVIEVPAVPEEILKRLLKEQHLWDVDLLDSKVIEILDSQT 1409 EQAELSYKKVSEGPPLRLWRSVIEVPAVPEEILKRLLKEQHLWDVDLLDSKVIEILDSQT Sbjct: 913 EQAELSYKKVSEGPPLRLWRSVIEVPAVPEEILKRLLKEQHLWDVDLLDSKVIEILDSQT 972 Query: 1410 EIYQYVQNSMAPHPARDYVVLRTWRTNLPKGACALLLTSVDHDRAPVVGVRVNVLLSRYL 1469 EIYQYVQNSMAPHPARDYVVLRTWRTNLPKGACALLLTSVDHDRAPVVGVRVNVLLSRYL Sbjct: 973 EIYQYVQNSMAPHPARDYVVLRTWRTNLPKGACALLLTSVDHDRAPVVGVRVNVLLSRYL 1032 Query: 1470 IEPCGPGKSKLTYMCRVDLRGHMPEWYTKSFGHLCAAEVVKIRDSFSNQNTETKDTKSR 1528 IEPCGPGKSKLTYMCRVDLRGHMPEWYTKSFGHLCAAEVVKIRDSFSNQNTETKDTKSR Sbjct: 1033 IEPCGPGKSKLTYMCRVDLRGHMPEWYTKSFGHLCAAEVVKIRDSFSNQNTETKDTKSR 1091 >gi|41281907 StAR-related lipid transfer (START) domain containing 13 isoform beta [Homo sapiens] Length = 1105 Score = 1102 bits (2849), Expect = 0.0 Identities = 606/1096 (55%), Positives = 776/1096 (70%), Gaps = 53/1096 (4%) Query: 447 EKAEIEAKEACDWLRATGFPQYAQLYEDFLFPIDISLVKREHDFLDRDAIEALCRRLNTL 506 ++ EIEAKEACDWLRA GFPQYAQLYED FPI+I VK +HDFL++D +E LCRRLNTL Sbjct: 46 QRREIEAKEACDWLRAAGFPQYAQLYEDSQFPINIVAVKNDHDFLEKDLVEPLCRRLNTL 105 Query: 507 NKCAVMKLEISPHRKRSDDSDEDEPCAISGKWTFQRDSKRWSRLEEFDVFSPKQDLVPGS 566 NKCA MKL+++ RK+ DDSDE++ C IS KWTFQR S+RWSR+++ P+ D GS Sbjct: 106 NKCASMKLDVNFQRKKGDDSDEEDLC-ISNKWTFQRTSRRWSRVDDLYTLLPRGDR-NGS 163 Query: 567 PDDSHPKDGPSPGGTLMDLSERQEVSSVRSLSSTGSLPSHAPPSEDAATPRTNSVISVCS 626 P + ++ S L DLSE EV S+ S SS GS S + P + C Sbjct: 164 PGGTGMRNTTSSESVLTDLSE-PEVCSIHSESSGGS-DSRSQPGQ-------------CC 208 Query: 627 SSNLAGNDDSF--GSLPSP-KELSSFSFSMKGHEKTAKSKTRSLLKRMESLKLKSSHHSK 683 + N D SLP P +++ + F K +EK +++ +S LKRME+L+ K +H + Sbjct: 209 TDNPVMLDAPLVSSSLPQPPRDVLNHPFHPK-NEKPTRARAKSFLKRMETLRGKGAH-GR 266 Query: 684 HKAPSKLG-LIISGPILQEGMDEEKLKQLNCVEISALNGNRINVPMVR-KRSVSNSTQTS 741 HK + G L+ISGP+LQ+ + E K + C++I NG+ N P ++ + S ++S Sbjct: 267 HKGSGRTGGLVISGPMLQQ--EPESFKAMQCIQIP--NGDLQNSPPPACRKGLPCSGKSS 322 Query: 742 SSSSQSE-TSSAVSTPSPVTRTRSLSACNKRVGMYLEGFDPFNQSTFNNVVEQNFKNRES 800 SS SE +SS VSTP + R NKR GMYLE D + + +Q+ + Sbjct: 323 GESSPSEHSSSGVSTPC--LKERKCHEANKRGGMYLEDLDVLAGTALPDAGDQSRMHEFH 380 Query: 801 YPEDTVFYIPEDHKPGTFPKALTNGSFSPSGNNGSVNWRTGSFHGPGHISLRRENSSDSP 860 E+ V +IP+DHKPGTFPKAL+ S SP+ ++ VNWRTGS ISL RE + Sbjct: 381 SQENLVVHIPKDHKPGTFPKALSIESLSPTDSSNGVNWRTGS------ISLGREQVPGAR 434 Query: 861 KELKRRNSSSSMSSRLSIYDNVPGSILYSSSGDLADLENEDIFPELDDILYHVKGMQRIV 920 + R +S +SR+SIYDNVPGS LY+S+GDL DLE +D+FP LDDIL HV G+Q +V Sbjct: 435 EP--RLMASCHRASRVSIYDNVPGSHLYASTGDLLDLEKDDLFPHLDDILQHVNGLQEVV 492 Query: 921 NQWSEKFSDEGDSDSAL---DSVSPCPSSPKQIHLD-----VDNDRTTPSDLDSTGNSLN 972 + WS+ E + L +S PS P QI LD V RTTPSD++ SLN Sbjct: 493 DDWSKDVLPELQTHDTLVGEPGLSTFPS-PNQITLDFEGNSVSEGRTTPSDVERDVTSLN 551 Query: 973 EPEEPSEIPERRDSGVGASLTRSNRHRLRWHSFQSSHRPSLNSVSLQINCQSVAQMNLLQ 1032 E E P + +RRDSGVGASLTR NR RLRW+SFQ SH+P S I+ Q+ +Q++LLQ Sbjct: 552 ESEPPG-VRDRRDSGVGASLTRPNR-RLRWNSFQLSHQPRPAPASPHISSQTASQLSLLQ 609 Query: 1033 KYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTGQPLP 1092 ++SLL+LTA++EK++ SNKHG++W+VPKFMKR+KVPDYKD++VFGVPL V+VQRTGQPLP Sbjct: 610 RFSLLRLTAIMEKHSMSNKHGWTWSVPKFMKRMKVPDYKDKAVFGVPLIVHVQRTGQPLP 669 Query: 1093 QSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADMLKQ 1152 QSIQQA+RYLR++CLDQVGLFRKSGVKSRI ALRQMNE + VNYE QSAYDVADM+KQ Sbjct: 670 QSIQQALRYLRSNCLDQVGLFRKSGVKSRIHALRQMNENFPENVNYEDQSAYDVADMVKQ 729 Query: 1153 YFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVT 1212 +FRDLPEPL TNKLSETFL IYQYV K+QRLQA++AAI+LL DENREVLQTLL FL+DV Sbjct: 730 FFRDLPEPLFTNKLSETFLHIYQYVSKEQRLQAVQAAILLLADENREVLQTLLCFLNDVV 789 Query: 1213 AAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQG 1272 V+ENQMTP NLAVCLAPSLFHLN LK+E SSPRV+Q+K + GKPDQKDLNENLAA QG Sbjct: 790 NLVEENQMTPMNLAVCLAPSLFHLNLLKKE-SSPRVIQKKYATGKPDQKDLNENLAAAQG 848 Query: 1273 LAHMIAECKKLFQVPEEM-SRCRNSYTEQELKPLTLEALGHLGNDDSADYQHFLQDCVDG 1331 LAHMI EC +LF+VP E+ ++ RNSY E E+ TLE LG + A + +L + G Sbjct: 849 LAHMIMECDRLFEVPHELVAQSRNSYVEAEIHVPTLEELGTQLEESGATFHTYLNHLIQG 908 Query: 1332 LFKEVKEKFKGWVSYSTSEQAELSYKKVSEGPPLRLWRSVIEVPAVPEEILKRLLKEQHL 1391 L KE KEKFKGWV+ S+++ +L++KKV +G PL+LW++ +EV A P +L R+L+E+HL Sbjct: 909 LQKEAKEKFKGWVTCSSTDNTDLAFKKVGDGNPLKLWKASVEVEAPPSVVLNRVLRERHL 968 Query: 1392 WDVDLLDSKVIEILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPKGACALLLTSVDH 1451 WD D + KV+E LD QTEIYQYV NSMAPHP+RD+VVLRTW+T+LPKG C L+ SV+H Sbjct: 969 WDEDFVQWKVVETLDRQTEIYQYVLNSMAPHPSRDFVVLRTWKTDLPKGMCTLVSLSVEH 1028 Query: 1452 DRAPVV-GVRVNVLLSRYLIEPCGPGKSKLTYMCRVDLRGHMPEWYTKSFGHLCAAEVVK 1510 + A ++ GVR V+ S+YLIEPCG GKS+LT++CR+DL+GH PEWY+K FGHLCAAEV + Sbjct: 1029 EEAQLLGGVRAVVMDSQYLIEPCGSGKSRLTHICRIDLKGHSPEWYSKGFGHLCAAEVAR 1088 Query: 1511 IRDSFSNQNTETKDTK 1526 IR+SF E +TK Sbjct: 1089 IRNSFQPLIAEGPETK 1104 >gi|41281898 StAR-related lipid transfer (START) domain containing 13 isoform alpha [Homo sapiens] Length = 1113 Score = 1101 bits (2848), Expect = 0.0 Identities = 607/1097 (55%), Positives = 776/1097 (70%), Gaps = 53/1097 (4%) Query: 446 KEKAEIEAKEACDWLRATGFPQYAQLYEDFLFPIDISLVKREHDFLDRDAIEALCRRLNT 505 K + EIEAKEACDWLRA GFPQYAQLYED FPI+I VK +HDFL++D +E LCRRLNT Sbjct: 53 KIQQEIEAKEACDWLRAAGFPQYAQLYEDSQFPINIVAVKNDHDFLEKDLVEPLCRRLNT 112 Query: 506 LNKCAVMKLEISPHRKRSDDSDEDEPCAISGKWTFQRDSKRWSRLEEFDVFSPKQDLVPG 565 LNKCA MKL+++ RK+ DDSDE++ C IS KWTFQR S+RWSR+++ P+ D G Sbjct: 113 LNKCASMKLDVNFQRKKGDDSDEEDLC-ISNKWTFQRTSRRWSRVDDLYTLLPRGDR-NG 170 Query: 566 SPDDSHPKDGPSPGGTLMDLSERQEVSSVRSLSSTGSLPSHAPPSEDAATPRTNSVISVC 625 SP + ++ S L DLSE EV S+ S SS GS S + P + C Sbjct: 171 SPGGTGMRNTTSSESVLTDLSE-PEVCSIHSESSGGS-DSRSQPGQ-------------C 215 Query: 626 SSSNLAGNDDSF--GSLPSP-KELSSFSFSMKGHEKTAKSKTRSLLKRMESLKLKSSHHS 682 + N D SLP P +++ + F K +EK +++ +S LKRME+L+ K +H Sbjct: 216 CTDNPVMLDAPLVSSSLPQPPRDVLNHPFHPK-NEKPTRARAKSFLKRMETLRGKGAH-G 273 Query: 683 KHKAPSKLG-LIISGPILQEGMDEEKLKQLNCVEISALNGNRINVPMVR-KRSVSNSTQT 740 +HK + G L+ISGP+LQ+ + E K + C++I NG+ N P ++ + S ++ Sbjct: 274 RHKGSGRTGGLVISGPMLQQ--EPESFKAMQCIQIP--NGDLQNSPPPACRKGLPCSGKS 329 Query: 741 SSSSSQSE-TSSAVSTPSPVTRTRSLSACNKRVGMYLEGFDPFNQSTFNNVVEQNFKNRE 799 S SS SE +SS VSTP + R NKR GMYLE D + + +Q+ + Sbjct: 330 SGESSPSEHSSSGVSTPC--LKERKCHEANKRGGMYLEDLDVLAGTALPDAGDQSRMHEF 387 Query: 800 SYPEDTVFYIPEDHKPGTFPKALTNGSFSPSGNNGSVNWRTGSFHGPGHISLRRENSSDS 859 E+ V +IP+DHKPGTFPKAL+ S SP+ ++ VNWRTGS ISL RE + Sbjct: 388 HSQENLVVHIPKDHKPGTFPKALSIESLSPTDSSNGVNWRTGS------ISLGREQVPGA 441 Query: 860 PKELKRRNSSSSMSSRLSIYDNVPGSILYSSSGDLADLENEDIFPELDDILYHVKGMQRI 919 + R +S +SR+SIYDNVPGS LY+S+GDL DLE +D+FP LDDIL HV G+Q + Sbjct: 442 REP--RLMASCHRASRVSIYDNVPGSHLYASTGDLLDLEKDDLFPHLDDILQHVNGLQEV 499 Query: 920 VNQWSEKFSDEGDSDSAL---DSVSPCPSSPKQIHLD-----VDNDRTTPSDLDSTGNSL 971 V+ WS+ E + L +S PS P QI LD V RTTPSD++ SL Sbjct: 500 VDDWSKDVLPELQTHDTLVGEPGLSTFPS-PNQITLDFEGNSVSEGRTTPSDVERDVTSL 558 Query: 972 NEPEEPSEIPERRDSGVGASLTRSNRHRLRWHSFQSSHRPSLNSVSLQINCQSVAQMNLL 1031 NE E P + +RRDSGVGASLTR NR RLRW+SFQ SH+P S I+ Q+ +Q++LL Sbjct: 559 NESEPPG-VRDRRDSGVGASLTRPNR-RLRWNSFQLSHQPRPAPASPHISSQTASQLSLL 616 Query: 1032 QKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTGQPL 1091 Q++SLL+LTA++EK++ SNKHG++W+VPKFMKR+KVPDYKD++VFGVPL V+VQRTGQPL Sbjct: 617 QRFSLLRLTAIMEKHSMSNKHGWTWSVPKFMKRMKVPDYKDKAVFGVPLIVHVQRTGQPL 676 Query: 1092 PQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADMLK 1151 PQSIQQA+RYLR++CLDQVGLFRKSGVKSRI ALRQMNE + VNYE QSAYDVADM+K Sbjct: 677 PQSIQQALRYLRSNCLDQVGLFRKSGVKSRIHALRQMNENFPENVNYEDQSAYDVADMVK 736 Query: 1152 QYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDV 1211 Q+FRDLPEPL TNKLSETFL IYQYV K+QRLQA++AAI+LL DENREVLQTLL FL+DV Sbjct: 737 QFFRDLPEPLFTNKLSETFLHIYQYVSKEQRLQAVQAAILLLADENREVLQTLLCFLNDV 796 Query: 1212 TAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQ 1271 V+ENQMTP NLAVCLAPSLFHLN LK+E SSPRV+Q+K + GKPDQKDLNENLAA Q Sbjct: 797 VNLVEENQMTPMNLAVCLAPSLFHLNLLKKE-SSPRVIQKKYATGKPDQKDLNENLAAAQ 855 Query: 1272 GLAHMIAECKKLFQVPEEM-SRCRNSYTEQELKPLTLEALGHLGNDDSADYQHFLQDCVD 1330 GLAHMI EC +LF+VP E+ ++ RNSY E E+ TLE LG + A + +L + Sbjct: 856 GLAHMIMECDRLFEVPHELVAQSRNSYVEAEIHVPTLEELGTQLEESGATFHTYLNHLIQ 915 Query: 1331 GLFKEVKEKFKGWVSYSTSEQAELSYKKVSEGPPLRLWRSVIEVPAVPEEILKRLLKEQH 1390 GL KE KEKFKGWV+ S+++ +L++KKV +G PL+LW++ +EV A P +L R+L+E+H Sbjct: 916 GLQKEAKEKFKGWVTCSSTDNTDLAFKKVGDGNPLKLWKASVEVEAPPSVVLNRVLRERH 975 Query: 1391 LWDVDLLDSKVIEILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPKGACALLLTSVD 1450 LWD D + KV+E LD QTEIYQYV NSMAPHP+RD+VVLRTW+T+LPKG C L+ SV+ Sbjct: 976 LWDEDFVQWKVVETLDRQTEIYQYVLNSMAPHPSRDFVVLRTWKTDLPKGMCTLVSLSVE 1035 Query: 1451 HDRAPVV-GVRVNVLLSRYLIEPCGPGKSKLTYMCRVDLRGHMPEWYTKSFGHLCAAEVV 1509 H+ A ++ GVR V+ S+YLIEPCG GKS+LT++CR+DL+GH PEWY+K FGHLCAAEV Sbjct: 1036 HEEAQLLGGVRAVVMDSQYLIEPCGSGKSRLTHICRIDLKGHSPEWYSKGFGHLCAAEVA 1095 Query: 1510 KIRDSFSNQNTETKDTK 1526 +IR+SF E +TK Sbjct: 1096 RIRNSFQPLIAEGPETK 1112 >gi|16445031 StAR-related lipid transfer (START) domain containing 13 isoform gamma [Homo sapiens] Length = 995 Score = 999 bits (2583), Expect = 0.0 Identities = 558/1031 (54%), Positives = 721/1031 (69%), Gaps = 53/1031 (5%) Query: 512 MKLEISPHRKRSDDSDEDEPCAISGKWTFQRDSKRWSRLEEFDVFSPKQDLVPGSPDDSH 571 MKL+++ RK+ DDSDE++ C IS KWTFQR S+RWSR+++ P+ D GSP + Sbjct: 1 MKLDVNFQRKKGDDSDEEDLC-ISNKWTFQRTSRRWSRVDDLYTLLPRGDR-NGSPGGTG 58 Query: 572 PKDGPSPGGTLMDLSERQEVSSVRSLSSTGSLPSHAPPSEDAATPRTNSVISVCSSSNLA 631 ++ S L DLSE EV S+ S SS GS S + P + C + N Sbjct: 59 MRNTTSSESVLTDLSE-PEVCSIHSESSGGS-DSRSQPGQ-------------CCTDNPV 103 Query: 632 GNDDSF--GSLPSP-KELSSFSFSMKGHEKTAKSKTRSLLKRMESLKLKSSHHSKHKAPS 688 D SLP P +++ + F K +EK +++ +S LKRME+L+ K +H +HK Sbjct: 104 MLDAPLVSSSLPQPPRDVLNHPFHPK-NEKPTRARAKSFLKRMETLRGKGAH-GRHKGSG 161 Query: 689 KLG-LIISGPILQEGMDEEKLKQLNCVEISALNGNRINVPMVR-KRSVSNSTQTSSSSSQ 746 + G L+ISGP+LQ+ + E K + C++I NG+ N P ++ + S ++S SS Sbjct: 162 RTGGLVISGPMLQQ--EPESFKAMQCIQIP--NGDLQNSPPPACRKGLPCSGKSSGESSP 217 Query: 747 SE-TSSAVSTPSPVTRTRSLSACNKRVGMYLEGFDPFNQSTFNNVVEQNFKNRESYPEDT 805 SE +SS VSTP + R NKR GMYLE D + + +Q+ + E+ Sbjct: 218 SEHSSSGVSTPC--LKERKCHEANKRGGMYLEDLDVLAGTALPDAGDQSRMHEFHSQENL 275 Query: 806 VFYIPEDHKPGTFPKALTNGSFSPSGNNGSVNWRTGSFHGPGHISLRRENSSDSPKELKR 865 V +IP+DHKPGTFPKAL+ S SP+ ++ VNWRTGS ISL RE + + R Sbjct: 276 VVHIPKDHKPGTFPKALSIESLSPTDSSNGVNWRTGS------ISLGREQVPGAREP--R 327 Query: 866 RNSSSSMSSRLSIYDNVPGSILYSSSGDLADLENEDIFPELDDILYHVKGMQRIVNQWSE 925 +S +SR+SIYDNVPGS LY+S+GDL DLE +D+FP LDDIL HV G+Q +V+ WS+ Sbjct: 328 LMASCHRASRVSIYDNVPGSHLYASTGDLLDLEKDDLFPHLDDILQHVNGLQEVVDDWSK 387 Query: 926 KFSDEGDSDSAL---DSVSPCPSSPKQIHLD-----VDNDRTTPSDLDSTGNSLNEPEEP 977 E + L +S PS P QI LD V RTTPSD++ SLNE E P Sbjct: 388 DVLPELQTHDTLVGEPGLSTFPS-PNQITLDFEGNSVSEGRTTPSDVERDVTSLNESEPP 446 Query: 978 SEIPERRDSGVGASLTRSNRHRLRWHSFQSSHRPSLNSVSLQINCQSVAQMNLLQKYSLL 1037 + +RRDSGVGASLTR NR RLRW+SFQ SH+P S I+ Q+ +Q++LLQ++SLL Sbjct: 447 G-VRDRRDSGVGASLTRPNR-RLRWNSFQLSHQPRPAPASPHISSQTASQLSLLQRFSLL 504 Query: 1038 KLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTGQPLPQSIQQ 1097 +LTA++EK++ SNKHG++W+VPKFMKR+KVPDYKD++VFGVPL V+VQRTGQPLPQSIQQ Sbjct: 505 RLTAIMEKHSMSNKHGWTWSVPKFMKRMKVPDYKDKAVFGVPLIVHVQRTGQPLPQSIQQ 564 Query: 1098 AMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADMLKQYFRDL 1157 A+RYLR++CLDQVGLFRKSGVKSRI ALRQMNE + VNYE QSAYDVADM+KQ+FRDL Sbjct: 565 ALRYLRSNCLDQVGLFRKSGVKSRIHALRQMNENFPENVNYEDQSAYDVADMVKQFFRDL 624 Query: 1158 PEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKE 1217 PEPL TNKLSETFL IYQYV K+QRLQA++AAI+LL DENREVLQTLL FL+DV V+E Sbjct: 625 PEPLFTNKLSETFLHIYQYVSKEQRLQAVQAAILLLADENREVLQTLLCFLNDVVNLVEE 684 Query: 1218 NQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMI 1277 NQMTP NLAVCLAPSLFHLN LK+E SSPRV+Q+K + GKPDQKDLNENLAA QGLAHMI Sbjct: 685 NQMTPMNLAVCLAPSLFHLNLLKKE-SSPRVIQKKYATGKPDQKDLNENLAAAQGLAHMI 743 Query: 1278 AECKKLFQVPEEM-SRCRNSYTEQELKPLTLEALGHLGNDDSADYQHFLQDCVDGLFKEV 1336 EC +LF+VP E+ ++ RNSY E E+ TLE LG + A + +L + GL KE Sbjct: 744 MECDRLFEVPHELVAQSRNSYVEAEIHVPTLEELGTQLEESGATFHTYLNHLIQGLQKEA 803 Query: 1337 KEKFKGWVSYSTSEQAELSYKKVSEGPPLRLWRSVIEVPAVPEEILKRLLKEQHLWDVDL 1396 KEKFKGWV+ S+++ +L++KKV +G PL+LW++ +EV A P +L R+L+E+HLWD D Sbjct: 804 KEKFKGWVTCSSTDNTDLAFKKVGDGNPLKLWKASVEVEAPPSVVLNRVLRERHLWDEDF 863 Query: 1397 LDSKVIEILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPKGACALLLTSVDHDRAPV 1456 + KV+E LD QTEIYQYV NSMAPHP+RD+VVLRTW+T+LPKG C L+ SV+H+ A + Sbjct: 864 VQWKVVETLDRQTEIYQYVLNSMAPHPSRDFVVLRTWKTDLPKGMCTLVSLSVEHEEAQL 923 Query: 1457 V-GVRVNVLLSRYLIEPCGPGKSKLTYMCRVDLRGHMPEWYTKSFGHLCAAEVVKIRDSF 1515 + GVR V+ S+YLIEPCG GKS+LT++CR+DL+GH PEWY+K FGHLCAAEV +IR+SF Sbjct: 924 LGGVRAVVMDSQYLIEPCGSGKSRLTHICRIDLKGHSPEWYSKGFGHLCAAEVARIRNSF 983 Query: 1516 SNQNTETKDTK 1526 E +TK Sbjct: 984 QPLIAEGPETK 994 >gi|33188435 deleted in liver cancer 1 isoform 3 [Homo sapiens] Length = 498 Score = 898 bits (2321), Expect = 0.0 Identities = 448/453 (98%), Positives = 452/453 (99%) Query: 1 MSVAIRKRSWEEHVTHWMGQPFNSDDRNTACHHGLVADSLQASMEKDATLNVDRKEKCVS 60 MSVAIRKRSWEEHVTHWMGQPFNSDDRNTACHHGLVADSLQASMEKDATLNVDRKEKCVS Sbjct: 1 MSVAIRKRSWEEHVTHWMGQPFNSDDRNTACHHGLVADSLQASMEKDATLNVDRKEKCVS 60 Query: 61 LPDCCHGSELRDFPGRPMGHLSKDVDENDSHEGEDQFLSLEASTETLVHVSDEDNNADLC 120 LPDCCHGSELRDFPGRPMGHLSKDVDENDSHEGEDQFLSLEASTETLVHVSDEDNNADLC Sbjct: 61 LPDCCHGSELRDFPGRPMGHLSKDVDENDSHEGEDQFLSLEASTETLVHVSDEDNNADLC 120 Query: 121 LTDDKQVLNTQGQKTSGQHMIQGAGSLEKALPIIQSNQVSSNSWGIAGETELALVKESGE 180 LTDDKQVLNTQGQKTSGQHMIQGAGSLEKALPIIQSNQVSSNSWGIAGETELALVKESGE Sbjct: 121 LTDDKQVLNTQGQKTSGQHMIQGAGSLEKALPIIQSNQVSSNSWGIAGETELALVKESGE 180 Query: 181 RKVTDSISKSLELCNEISLSEIKDAPKVNAVDTLNVKDIAPEKQLLNSAVIAQQRRKPDP 240 RKVTDSISKSLELCNEISLSEIKDAPKVNAVDTLNVKDIAPEKQLLNSAVIAQQRRKPDP Sbjct: 181 RKVTDSISKSLELCNEISLSEIKDAPKVNAVDTLNVKDIAPEKQLLNSAVIAQQRRKPDP 240 Query: 241 PKDENERSTCNVVQDEFLDTPCTNRGLPLLKTDFGSCLLQPPSCPNGMSAENGLEKSGFS 300 PKDENERSTCNVVQ+EFLDTPCTNRGLPLLKTDFGSCLLQPPSCPNGMSAENGLEKSGFS Sbjct: 241 PKDENERSTCNVVQNEFLDTPCTNRGLPLLKTDFGSCLLQPPSCPNGMSAENGLEKSGFS 300 Query: 301 QHQNKSPPKVKAEDGMQCLQLKETLATQEPTDNQVRLRKRKEIREDRDRARLDSMVLLIM 360 QHQNKSPPKVKAEDGMQCLQLKETLATQEPTDNQVRLRKRKEIREDRDRARLDSMVLLIM Sbjct: 301 QHQNKSPPKVKAEDGMQCLQLKETLATQEPTDNQVRLRKRKEIREDRDRARLDSMVLLIM 360 Query: 361 KLDQLDQDIENALSTSSSPSGTPTNLRRHVPDLESGSESGADTISVNQTRVNLSSDTEST 420 KLDQLDQDIENALSTSSSPSGTPTNLRRHVPDLESGSESGADTISVNQTRVNLSSDTEST Sbjct: 361 KLDQLDQDIENALSTSSSPSGTPTNLRRHVPDLESGSESGADTISVNQTRVNLSSDTEST 420 Query: 421 DLPSSTPVANSGTKPKTTAIQGISEKEKAEIEA 453 DLPSSTPVANSGTKPKTTAIQGISEKEKA +++ Sbjct: 421 DLPSSTPVANSGTKPKTTAIQGISEKEKAAVKS 453 >gi|215820652 StAR-related lipid transfer (START) domain containing 8 isoform b [Homo sapiens] Length = 1023 Score = 653 bits (1684), Expect = 0.0 Identities = 335/577 (58%), Positives = 430/577 (74%), Gaps = 15/577 (2%) Query: 962 SDLDSTGNSLNEPEEPSEIP--------ERRDSGVGASLTRSNRHRLRWHSFQSSHRPSL 1013 S+LDS+GNS+NE E + ERRDSGVGASLTR R +LRWHSFQ+SHRPSL Sbjct: 449 SELDSSGNSMNEAEAAGPLAGLQASMPRERRDSGVGASLTRPCR-KLRWHSFQNSHRPSL 507 Query: 1014 NSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDR 1073 NS SL+IN Q Q+NLL K SLL+LTA +EKYT +K G+ W++PKFM+R K PDY+ + Sbjct: 508 NSESLEINRQFAGQINLLHKGSLLRLTAFMEKYTVPHKQGWVWSMPKFMRRNKTPDYRGQ 567 Query: 1074 SVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAI 1133 VFGVP ++VQRTGQPLPQSIQQAMRYLR+ CLDQVG+FRKSGVKSRIQ LRQMNE + Sbjct: 568 HVFGVPPLIHVQRTGQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNETSP 627 Query: 1134 DCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLL 1193 D V YEGQSAYDVAD+LKQYFRDLPEP+ T+KL+ TFLQIYQ +PKDQ L A +AA +LL Sbjct: 628 DNVCYEGQSAYDVADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAAAQAATLLL 687 Query: 1194 PDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQ 1253 PDENREVLQTLLYFLSD+ A+ +ENQMT NLAVCLAPS+FHLN K+++ SPR+ ++ Sbjct: 688 PDENREVLQTLLYFLSDI-ASAEENQMTAGNLAVCLAPSIFHLNVSKKDSPSPRIKSKRS 746 Query: 1254 SLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEM-SRCRNSYTEQELKPLTLEALGH 1312 +G+P +DL++N+AATQGL+HMI++CKKLFQVP++M + +SY+ EL P AL Sbjct: 747 LIGRPGPRDLSDNMAATQGLSHMISDCKKLFQVPQDMVLQLCSSYSAAELSP-PGPALAE 805 Query: 1313 LGNDDSA--DYQHFLQDCVDGLFKEVKEKFKGWVSYSTSEQAELSYKKVSEGPPLRLWRS 1370 L +A ++++ + L ++ E+FKGW+S + EL+ +K +G PLRLW++ Sbjct: 806 LRQAQAAGVSLSLYMEENIQDLLRDAAERFKGWMSVPGPQHTELACRKAPDGHPLRLWKA 865 Query: 1371 VIEVPAVPEEILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQNSMAPHPARDYVVL 1430 EV A P +L R+L+E+ LWD DLL ++V+E L E+Y YV +SMAPHP RD+VVL Sbjct: 866 STEVAAPPAVVLHRVLRERALWDEDLLRAQVLEALMPGVELYHYVTDSMAPHPCRDFVVL 925 Query: 1431 RTWRTNLPKGACALLLTSVDHDR-APVVGVRVNVLLSRYLIEPCGPGKSKLTYMCRVDLR 1489 R WR++LP+G C L+ S+D ++ P GVR +L S+YL+EPCG G+S+LT++CR DLR Sbjct: 926 RMWRSDLPRGGCLLVSQSLDPEQPVPESGVRALMLTSQYLMEPCGLGRSRLTHICRADLR 985 Query: 1490 GHMPEWYTKSFGHLCAAEVVKIRDSFSNQNTETKDTK 1526 G P+WY K FGHLCA EV KIRDSF +TK Sbjct: 986 GRSPDWYNKVFGHLCAMEVAKIRDSFPTLQAAGPETK 1022 Score = 69.7 bits (169), Expect = 2e-11 Identities = 60/187 (32%), Positives = 82/187 (43%), Gaps = 43/187 (22%) Query: 505 TLNKCAVMKLEISPHRKRSDDSDEDEPCAISGKWTFQRDSKRWSRLEEFDVFSPKQDLVP 564 TLN CA MKLE+ K+++DS+E+E C IS W FQ++SK WS + D+ +P Sbjct: 2 TLNNCASMKLEVHFQSKQNEDSEEEEQCTISSHWAFQQESKCWSPMGSSDLLAP------ 55 Query: 565 GSPDDSHPKDGPSPGGTLMDLSERQEVSSVRSLSSTGSLP--SHAPPSEDAATPRTNSVI 622 PSPG L SV + S SLP + + P E A P Sbjct: 56 -----------PSPG-----LPATSSCESVLTELSATSLPVITVSLPPEPADLP------ 93 Query: 623 SVCSSSNLAGNDDSFGSLPSPKELSSFSFSMKGHEKTAKS--KTRSLLKRMESLKLKSSH 680 L G S S + L S + +G + AK + RS LK +ESL+ K Sbjct: 94 -------LPGRAPS----SSDRPLLSPTQGQEGPQDKAKKRHRNRSFLKHLESLRRKEKS 142 Query: 681 HSKHKAP 687 S+ P Sbjct: 143 GSQQAEP 149 Score = 65.9 bits (159), Expect = 3e-10 Identities = 59/217 (27%), Positives = 85/217 (39%), Gaps = 45/217 (20%) Query: 742 SSSSQSETSSAVSTPSPVTRTRSLSACNKRVGMYLEGFDPFNQSTFNNVVEQNFKNRESY 801 S S Q+E + +T V++ S +C G GF + R+++ Sbjct: 142 SGSQQAEPKHSPATSEKVSKASSFRSCR---GFLSAGFYRAKNWAATSAGGSGANTRKAW 198 Query: 802 PE---------------DTVFYIPEDHKPGTFPKALTNGSFSPSGNNGSVNWRTGSFHGP 846 D + ++P DHKPGTFP++L+ S P + +W+ G Sbjct: 199 EAWPVASFRHPQWTHRGDCLVHVPGDHKPGTFPRSLSIESLCPEDGHRLADWQPG----- 253 Query: 847 GHISLRRENSSDSPKELKRRNSSSSMSSRLSIYDNVPGSILYSSSGDLADLENED----- 901 RR RR S S S S YDN+P LY + + E ED Sbjct: 254 -----RRWGCEG------RRGSCGSTGSHASTYDNLPE--LYPAEPVMVGAEAEDEDDEE 300 Query: 902 ---IFPELDDILYHVKGMQRIVNQWSE-KFSDEGDSD 934 + LDDIL HV G+Q+ V WS + D G D Sbjct: 301 SGGSYAHLDDILQHVWGLQQRVELWSRAMYPDLGPGD 337 >gi|215820650 StAR-related lipid transfer (START) domain containing 8 isoform a [Homo sapiens] Length = 1103 Score = 653 bits (1684), Expect = 0.0 Identities = 335/577 (58%), Positives = 430/577 (74%), Gaps = 15/577 (2%) Query: 962 SDLDSTGNSLNEPEEPSEIP--------ERRDSGVGASLTRSNRHRLRWHSFQSSHRPSL 1013 S+LDS+GNS+NE E + ERRDSGVGASLTR R +LRWHSFQ+SHRPSL Sbjct: 529 SELDSSGNSMNEAEAAGPLAGLQASMPRERRDSGVGASLTRPCR-KLRWHSFQNSHRPSL 587 Query: 1014 NSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDR 1073 NS SL+IN Q Q+NLL K SLL+LTA +EKYT +K G+ W++PKFM+R K PDY+ + Sbjct: 588 NSESLEINRQFAGQINLLHKGSLLRLTAFMEKYTVPHKQGWVWSMPKFMRRNKTPDYRGQ 647 Query: 1074 SVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAI 1133 VFGVP ++VQRTGQPLPQSIQQAMRYLR+ CLDQVG+FRKSGVKSRIQ LRQMNE + Sbjct: 648 HVFGVPPLIHVQRTGQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNETSP 707 Query: 1134 DCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLL 1193 D V YEGQSAYDVAD+LKQYFRDLPEP+ T+KL+ TFLQIYQ +PKDQ L A +AA +LL Sbjct: 708 DNVCYEGQSAYDVADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAAAQAATLLL 767 Query: 1194 PDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQ 1253 PDENREVLQTLLYFLSD+ A+ +ENQMT NLAVCLAPS+FHLN K+++ SPR+ ++ Sbjct: 768 PDENREVLQTLLYFLSDI-ASAEENQMTAGNLAVCLAPSIFHLNVSKKDSPSPRIKSKRS 826 Query: 1254 SLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEM-SRCRNSYTEQELKPLTLEALGH 1312 +G+P +DL++N+AATQGL+HMI++CKKLFQVP++M + +SY+ EL P AL Sbjct: 827 LIGRPGPRDLSDNMAATQGLSHMISDCKKLFQVPQDMVLQLCSSYSAAELSP-PGPALAE 885 Query: 1313 LGNDDSA--DYQHFLQDCVDGLFKEVKEKFKGWVSYSTSEQAELSYKKVSEGPPLRLWRS 1370 L +A ++++ + L ++ E+FKGW+S + EL+ +K +G PLRLW++ Sbjct: 886 LRQAQAAGVSLSLYMEENIQDLLRDAAERFKGWMSVPGPQHTELACRKAPDGHPLRLWKA 945 Query: 1371 VIEVPAVPEEILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQNSMAPHPARDYVVL 1430 EV A P +L R+L+E+ LWD DLL ++V+E L E+Y YV +SMAPHP RD+VVL Sbjct: 946 STEVAAPPAVVLHRVLRERALWDEDLLRAQVLEALMPGVELYHYVTDSMAPHPCRDFVVL 1005 Query: 1431 RTWRTNLPKGACALLLTSVDHDR-APVVGVRVNVLLSRYLIEPCGPGKSKLTYMCRVDLR 1489 R WR++LP+G C L+ S+D ++ P GVR +L S+YL+EPCG G+S+LT++CR DLR Sbjct: 1006 RMWRSDLPRGGCLLVSQSLDPEQPVPESGVRALMLTSQYLMEPCGLGRSRLTHICRADLR 1065 Query: 1490 GHMPEWYTKSFGHLCAAEVVKIRDSFSNQNTETKDTK 1526 G P+WY K FGHLCA EV KIRDSF +TK Sbjct: 1066 GRSPDWYNKVFGHLCAMEVAKIRDSFPTLQAAGPETK 1102 Score = 149 bits (375), Expect = 3e-35 Identities = 97/246 (39%), Positives = 128/246 (52%), Gaps = 43/246 (17%) Query: 446 KEKAEIEAKEACDWLRATGFPQYAQLYEDFLFPIDISLVKREHDFLDRDAIEALCRRLNT 505 K+ AE EAK AC+WL+ATGFPQY QL+E+ FP+DI VK+ H FLD D++ ALCRRL T Sbjct: 23 KKNAEAEAKRACEWLQATGFPQYVQLFEEGSFPLDIGSVKKNHGFLDEDSLGALCRRLMT 82 Query: 506 LNKCAVMKLEISPHRKRSDDSDEDEPCAISGKWTFQRDSKRWSRLEEFDVFSPKQDLVPG 565 LN CA MKLE+ K+++DS+E+E C IS W FQ++SK WS + D+ +P Sbjct: 83 LNNCASMKLEVHFQSKQNEDSEEEEQCTISSHWAFQQESKCWSPMGSSDLLAP------- 135 Query: 566 SPDDSHPKDGPSPGGTLMDLSERQEVSSVRSLSSTGSLP--SHAPPSEDAATPRTNSVIS 623 PSPG L SV + S SLP + + P E A P Sbjct: 136 ----------PSPG-----LPATSSCESVLTELSATSLPVITVSLPPEPADLP------- 173 Query: 624 VCSSSNLAGNDDSFGSLPSPKELSSFSFSMKGHEKTAKS--KTRSLLKRMESLKLKSSHH 681 L G S S + L S + +G + AK + RS LK +ESL+ K Sbjct: 174 ------LPGRAPS----SSDRPLLSPTQGQEGPQDKAKKRHRNRSFLKHLESLRRKEKSG 223 Query: 682 SKHKAP 687 S+ P Sbjct: 224 SQQAEP 229 Score = 65.9 bits (159), Expect = 3e-10 Identities = 59/217 (27%), Positives = 85/217 (39%), Gaps = 45/217 (20%) Query: 742 SSSSQSETSSAVSTPSPVTRTRSLSACNKRVGMYLEGFDPFNQSTFNNVVEQNFKNRESY 801 S S Q+E + +T V++ S +C G GF + R+++ Sbjct: 222 SGSQQAEPKHSPATSEKVSKASSFRSCR---GFLSAGFYRAKNWAATSAGGSGANTRKAW 278 Query: 802 PE---------------DTVFYIPEDHKPGTFPKALTNGSFSPSGNNGSVNWRTGSFHGP 846 D + ++P DHKPGTFP++L+ S P + +W+ G Sbjct: 279 EAWPVASFRHPQWTHRGDCLVHVPGDHKPGTFPRSLSIESLCPEDGHRLADWQPG----- 333 Query: 847 GHISLRRENSSDSPKELKRRNSSSSMSSRLSIYDNVPGSILYSSSGDLADLENED----- 901 RR RR S S S S YDN+P LY + + E ED Sbjct: 334 -----RRWGCEG------RRGSCGSTGSHASTYDNLPE--LYPAEPVMVGAEAEDEDDEE 380 Query: 902 ---IFPELDDILYHVKGMQRIVNQWSE-KFSDEGDSD 934 + LDDIL HV G+Q+ V WS + D G D Sbjct: 381 SGGSYAHLDDILQHVWGLQQRVELWSRAMYPDLGPGD 417 >gi|31543659 StAR-related lipid transfer (START) domain containing 8 isoform b [Homo sapiens] Length = 1023 Score = 653 bits (1684), Expect = 0.0 Identities = 335/577 (58%), Positives = 430/577 (74%), Gaps = 15/577 (2%) Query: 962 SDLDSTGNSLNEPEEPSEIP--------ERRDSGVGASLTRSNRHRLRWHSFQSSHRPSL 1013 S+LDS+GNS+NE E + ERRDSGVGASLTR R +LRWHSFQ+SHRPSL Sbjct: 449 SELDSSGNSMNEAEAAGPLAGLQASMPRERRDSGVGASLTRPCR-KLRWHSFQNSHRPSL 507 Query: 1014 NSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDR 1073 NS SL+IN Q Q+NLL K SLL+LTA +EKYT +K G+ W++PKFM+R K PDY+ + Sbjct: 508 NSESLEINRQFAGQINLLHKGSLLRLTAFMEKYTVPHKQGWVWSMPKFMRRNKTPDYRGQ 567 Query: 1074 SVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAI 1133 VFGVP ++VQRTGQPLPQSIQQAMRYLR+ CLDQVG+FRKSGVKSRIQ LRQMNE + Sbjct: 568 HVFGVPPLIHVQRTGQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNETSP 627 Query: 1134 DCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLL 1193 D V YEGQSAYDVAD+LKQYFRDLPEP+ T+KL+ TFLQIYQ +PKDQ L A +AA +LL Sbjct: 628 DNVCYEGQSAYDVADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAAAQAATLLL 687 Query: 1194 PDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQ 1253 PDENREVLQTLLYFLSD+ A+ +ENQMT NLAVCLAPS+FHLN K+++ SPR+ ++ Sbjct: 688 PDENREVLQTLLYFLSDI-ASAEENQMTAGNLAVCLAPSIFHLNVSKKDSPSPRIKSKRS 746 Query: 1254 SLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEM-SRCRNSYTEQELKPLTLEALGH 1312 +G+P +DL++N+AATQGL+HMI++CKKLFQVP++M + +SY+ EL P AL Sbjct: 747 LIGRPGPRDLSDNMAATQGLSHMISDCKKLFQVPQDMVLQLCSSYSAAELSP-PGPALAE 805 Query: 1313 LGNDDSA--DYQHFLQDCVDGLFKEVKEKFKGWVSYSTSEQAELSYKKVSEGPPLRLWRS 1370 L +A ++++ + L ++ E+FKGW+S + EL+ +K +G PLRLW++ Sbjct: 806 LRQAQAAGVSLSLYMEENIQDLLRDAAERFKGWMSVPGPQHTELACRKAPDGHPLRLWKA 865 Query: 1371 VIEVPAVPEEILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQNSMAPHPARDYVVL 1430 EV A P +L R+L+E+ LWD DLL ++V+E L E+Y YV +SMAPHP RD+VVL Sbjct: 866 STEVAAPPAVVLHRVLRERALWDEDLLRAQVLEALMPGVELYHYVTDSMAPHPCRDFVVL 925 Query: 1431 RTWRTNLPKGACALLLTSVDHDR-APVVGVRVNVLLSRYLIEPCGPGKSKLTYMCRVDLR 1489 R WR++LP+G C L+ S+D ++ P GVR +L S+YL+EPCG G+S+LT++CR DLR Sbjct: 926 RMWRSDLPRGGCLLVSQSLDPEQPVPESGVRALMLTSQYLMEPCGLGRSRLTHICRADLR 985 Query: 1490 GHMPEWYTKSFGHLCAAEVVKIRDSFSNQNTETKDTK 1526 G P+WY K FGHLCA EV KIRDSF +TK Sbjct: 986 GRSPDWYNKVFGHLCAMEVAKIRDSFPTLQAAGPETK 1022 Score = 69.7 bits (169), Expect = 2e-11 Identities = 60/187 (32%), Positives = 82/187 (43%), Gaps = 43/187 (22%) Query: 505 TLNKCAVMKLEISPHRKRSDDSDEDEPCAISGKWTFQRDSKRWSRLEEFDVFSPKQDLVP 564 TLN CA MKLE+ K+++DS+E+E C IS W FQ++SK WS + D+ +P Sbjct: 2 TLNNCASMKLEVHFQSKQNEDSEEEEQCTISSHWAFQQESKCWSPMGSSDLLAP------ 55 Query: 565 GSPDDSHPKDGPSPGGTLMDLSERQEVSSVRSLSSTGSLP--SHAPPSEDAATPRTNSVI 622 PSPG L SV + S SLP + + P E A P Sbjct: 56 -----------PSPG-----LPATSSCESVLTELSATSLPVITVSLPPEPADLP------ 93 Query: 623 SVCSSSNLAGNDDSFGSLPSPKELSSFSFSMKGHEKTAKS--KTRSLLKRMESLKLKSSH 680 L G S S + L S + +G + AK + RS LK +ESL+ K Sbjct: 94 -------LPGRAPS----SSDRPLLSPTQGQEGPQDKAKKRHRNRSFLKHLESLRRKEKS 142 Query: 681 HSKHKAP 687 S+ P Sbjct: 143 GSQQAEP 149 Score = 65.9 bits (159), Expect = 3e-10 Identities = 59/217 (27%), Positives = 85/217 (39%), Gaps = 45/217 (20%) Query: 742 SSSSQSETSSAVSTPSPVTRTRSLSACNKRVGMYLEGFDPFNQSTFNNVVEQNFKNRESY 801 S S Q+E + +T V++ S +C G GF + R+++ Sbjct: 142 SGSQQAEPKHSPATSEKVSKASSFRSCR---GFLSAGFYRAKNWAATSAGGSGANTRKAW 198 Query: 802 PE---------------DTVFYIPEDHKPGTFPKALTNGSFSPSGNNGSVNWRTGSFHGP 846 D + ++P DHKPGTFP++L+ S P + +W+ G Sbjct: 199 EAWPVASFRHPQWTHRGDCLVHVPGDHKPGTFPRSLSIESLCPEDGHRLADWQPG----- 253 Query: 847 GHISLRRENSSDSPKELKRRNSSSSMSSRLSIYDNVPGSILYSSSGDLADLENED----- 901 RR RR S S S S YDN+P LY + + E ED Sbjct: 254 -----RRWGCEG------RRGSCGSTGSHASTYDNLPE--LYPAEPVMVGAEAEDEDDEE 300 Query: 902 ---IFPELDDILYHVKGMQRIVNQWSE-KFSDEGDSD 934 + LDDIL HV G+Q+ V WS + D G D Sbjct: 301 SGGSYAHLDDILQHVWGLQQRVELWSRAMYPDLGPGD 337 >gi|39932589 Rho GTPase activating protein 18 [Homo sapiens] Length = 663 Score = 99.4 bits (246), Expect = 2e-20 Identities = 64/195 (32%), Positives = 103/195 (52%), Gaps = 8/195 (4%) Query: 1060 KFMKRIKVPDYKDRSVFGVPLTVNVQRT-----GQPLPQSIQQAMRYLRNHCLDQVGLFR 1114 K K +K+ KD +F VPLT +++ G +P Q+ + + L+ GL R Sbjct: 307 KQQKAVKIKT-KDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGLLR 365 Query: 1115 KSGVKSRIQALRQMNEGAI--DCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQ 1172 G RI+ L Q E N+E +D A +LK + R+LP+PL++ + + F Sbjct: 366 IPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQA 425 Query: 1173 IYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPS 1232 + K Q+LQA+ ++LLPD NR+ L+ LL FL V ++N+MT N+A+ +AP+ Sbjct: 426 VQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMAPN 485 Query: 1233 LFHLNTLKRENSSPR 1247 LF + L ++S R Sbjct: 486 LFMCHALGLKSSEQR 500 >gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens] Length = 771 Score = 91.7 bits (226), Expect = 5e-18 Identities = 65/211 (30%), Positives = 100/211 (47%), Gaps = 23/211 (10%) Query: 1091 LPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADML 1150 +P+ + ++L H L VG+FR K R++ LR+ + ID E S +DVA +L Sbjct: 207 VPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALL 266 Query: 1151 KQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSD 1210 K++ RD+P+PL+T +L F+ P++Q L ++ I LLP N + L LL FLS Sbjct: 267 KEFLRDMPDPLLTRELYTAFINTLLLEPEEQ-LGTLQLLIYLLPPCNCDTLHRLLQFLSI 325 Query: 1211 VT-----------AAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPD 1259 V V N+MT NLA P+L H ++ SS + + S Sbjct: 326 VARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLH-----KQKSSDKEFSVQSS----- 375 Query: 1260 QKDLNENLAATQGLAHMIAECKKLFQVPEEM 1290 E+ A + MI + LF VP ++ Sbjct: 376 -ARAEESTAIIAVVQKMIENYEALFMVPPDL 405 >gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo sapiens] Length = 765 Score = 91.7 bits (226), Expect = 5e-18 Identities = 65/211 (30%), Positives = 100/211 (47%), Gaps = 23/211 (10%) Query: 1091 LPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADML 1150 +P+ + ++L H L VG+FR K R++ LR+ + ID E S +DVA +L Sbjct: 410 VPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALL 469 Query: 1151 KQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSD 1210 K++ RD+P+PL+T +L F+ P++Q L ++ I LLP N + L LL FLS Sbjct: 470 KEFLRDMPDPLLTRELYTAFINTLLLEPEEQ-LGTLQLLIYLLPPCNCDTLHRLLQFLSI 528 Query: 1211 VT-----------AAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPD 1259 V V N+MT NLA P+L H ++ SS + + S Sbjct: 529 VARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLH-----KQKSSDKEFSVQSS----- 578 Query: 1260 QKDLNENLAATQGLAHMIAECKKLFQVPEEM 1290 E+ A + MI + LF VP ++ Sbjct: 579 -ARAEESTAIIAVVQKMIENYEALFMVPPDL 608 >gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo sapiens] Length = 974 Score = 91.7 bits (226), Expect = 5e-18 Identities = 65/211 (30%), Positives = 100/211 (47%), Gaps = 23/211 (10%) Query: 1091 LPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADML 1150 +P+ + ++L H L VG+FR K R++ LR+ + ID E S +DVA +L Sbjct: 410 VPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALL 469 Query: 1151 KQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSD 1210 K++ RD+P+PL+T +L F+ P++Q L ++ I LLP N + L LL FLS Sbjct: 470 KEFLRDMPDPLLTRELYTAFINTLLLEPEEQ-LGTLQLLIYLLPPCNCDTLHRLLQFLSI 528 Query: 1211 VT-----------AAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPD 1259 V V N+MT NLA P+L H ++ SS + + S Sbjct: 529 VARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLH-----KQKSSDKEFSVQSS----- 578 Query: 1260 QKDLNENLAATQGLAHMIAECKKLFQVPEEM 1290 E+ A + MI + LF VP ++ Sbjct: 579 -ARAEESTAIIAVVQKMIENYEALFMVPPDL 608 >gi|239757488 PREDICTED: chromosome 20 open reading frame 95 [Homo sapiens] Length = 622 Score = 88.2 bits (217), Expect = 6e-17 Identities = 64/220 (29%), Positives = 106/220 (48%), Gaps = 21/220 (9%) Query: 1024 SVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYK--DRSVFGVPLT 1081 S+ M + +L++LTAL + + +KR K +K + +FGVPL Sbjct: 226 SLQDMRKVPSLALIELTALCD------------ILGLDLKRSKAGKWKAAETRLFGVPLD 273 Query: 1082 VNVQRTGQPLPQS-----IQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCV 1136 ++ + LP + +Q + L LD G+ R G ++R++ L Q E Sbjct: 274 SLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGILRVPGSQARVKGLEQKLERDFYAG 333 Query: 1137 NYEGQSAY--DVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLP 1194 + + D +D+LK++ R LP PL+T + F + QRLQ + I++LP Sbjct: 334 LFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAFAVVPNIPNLKQRLQVLHLLILILP 393 Query: 1195 DENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLF 1234 + NR L+ LL FL V A + N+MT N++ +AP+LF Sbjct: 394 EPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMAPNLF 433 >gi|239752003 PREDICTED: chromosome 20 open reading frame 95 [Homo sapiens] Length = 622 Score = 88.2 bits (217), Expect = 6e-17 Identities = 64/220 (29%), Positives = 106/220 (48%), Gaps = 21/220 (9%) Query: 1024 SVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYK--DRSVFGVPLT 1081 S+ M + +L++LTAL + + +KR K +K + +FGVPL Sbjct: 226 SLQDMRKVPSLALIELTALCD------------ILGLDLKRSKAGKWKAAETRLFGVPLD 273 Query: 1082 VNVQRTGQPLPQS-----IQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCV 1136 ++ + LP + +Q + L LD G+ R G ++R++ L Q E Sbjct: 274 SLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGILRVPGSQARVKGLEQKLERDFYAG 333 Query: 1137 NYEGQSAY--DVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLP 1194 + + D +D+LK++ R LP PL+T + F + QRLQ + I++LP Sbjct: 334 LFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAFAVVPNIPNLKQRLQVLHLLILILP 393 Query: 1195 DENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLF 1234 + NR L+ LL FL V A + N+MT N++ +AP+LF Sbjct: 394 EPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMAPNLF 433 >gi|239746488 PREDICTED: Rho GTPase-activating protein 18-like [Homo sapiens] Length = 622 Score = 88.2 bits (217), Expect = 6e-17 Identities = 64/220 (29%), Positives = 106/220 (48%), Gaps = 21/220 (9%) Query: 1024 SVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYK--DRSVFGVPLT 1081 S+ M + +L++LTAL + + +KR K +K + +FGVPL Sbjct: 226 SLQDMRKVPSLALIELTALCD------------ILGLDLKRSKAGKWKAAETRLFGVPLD 273 Query: 1082 VNVQRTGQPLPQS-----IQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCV 1136 ++ + LP + +Q + L LD G+ R G ++R++ L Q E Sbjct: 274 SLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGILRVPGSQARVKGLEQKLERDFYAG 333 Query: 1137 NYEGQSAY--DVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLP 1194 + + D +D+LK++ R LP PL+T + F + QRLQ + I++LP Sbjct: 334 LFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAFAVVPNIPNLKQRLQVLHLLILILP 393 Query: 1195 DENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLF 1234 + NR L+ LL FL V A + N+MT N++ +AP+LF Sbjct: 394 EPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMAPNLF 433 >gi|54860079 nadrin isoform 1 [Homo sapiens] Length = 881 Score = 88.2 bits (217), Expect = 6e-17 Identities = 61/201 (30%), Positives = 97/201 (48%), Gaps = 23/201 (11%) Query: 1038 KLTALLEKYTPSNK-HGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTGQPLPQSIQ 1096 K A+LEK P + H WA ++ FG PL +++R+G+ + I+ Sbjct: 225 KALAVLEKTLPEMRAHQDKWA--------------EKPAFGTPLEEHLKRSGREIALPIE 270 Query: 1097 QAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYD----VADMLKQ 1152 + L + + GLFR S+++ L+ A+DC Y VA LK Sbjct: 271 ACVMLLLETGMKEEGLFRIGAGASKLKKLK----AALDCSTSHLDEFYSDPHAVAGALKS 326 Query: 1153 YFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVT 1212 Y R+LPEPLMT L E + Q+ +D++LQ + LP +N + L+ FL+ + Sbjct: 327 YLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKLPPQNFVNFRYLIKFLAKLA 386 Query: 1213 AAVKENQMTPTNLAVCLAPSL 1233 N+MTP+N+A+ L P+L Sbjct: 387 QTSDVNKMTPSNIAIVLGPNL 407 >gi|54860105 nadrin isoform 2 [Homo sapiens] Length = 803 Score = 88.2 bits (217), Expect = 6e-17 Identities = 61/201 (30%), Positives = 97/201 (48%), Gaps = 23/201 (11%) Query: 1038 KLTALLEKYTPSNK-HGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTGQPLPQSIQ 1096 K A+LEK P + H WA ++ FG PL +++R+G+ + I+ Sbjct: 225 KALAVLEKTLPEMRAHQDKWA--------------EKPAFGTPLEEHLKRSGREIALPIE 270 Query: 1097 QAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYD----VADMLKQ 1152 + L + + GLFR S+++ L+ A+DC Y VA LK Sbjct: 271 ACVMLLLETGMKEEGLFRIGAGASKLKKLK----AALDCSTSHLDEFYSDPHAVAGALKS 326 Query: 1153 YFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVT 1212 Y R+LPEPLMT L E + Q+ +D++LQ + LP +N + L+ FL+ + Sbjct: 327 YLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKLPPQNFVNFRYLIKFLAKLA 386 Query: 1213 AAVKENQMTPTNLAVCLAPSL 1233 N+MTP+N+A+ L P+L Sbjct: 387 QTSDVNKMTPSNIAIVLGPNL 407 >gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens] Length = 818 Score = 84.7 bits (208), Expect = 6e-16 Identities = 54/166 (32%), Positives = 94/166 (56%), Gaps = 8/166 (4%) Query: 1072 DRSVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEG 1131 ++ FG PL ++ +G+ + I+ + L + + GLFR + S+++ L+ Sbjct: 249 EKPSFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLK----A 304 Query: 1132 AIDC--VNYEGQSA--YDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIK 1187 A+DC V+ + SA + +A LK Y R+LPEPLMT +L + ++Q +D++LQA+ Sbjct: 305 ALDCCVVDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALW 364 Query: 1188 AAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSL 1233 A LP N ++ L+ FLS ++ N+MTP+N+A+ L P+L Sbjct: 365 NACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNL 410 >gi|59710113 Rho GTPase activating protein 28 isoform a [Homo sapiens] Length = 570 Score = 83.6 bits (205), Expect = 1e-15 Identities = 61/219 (27%), Positives = 106/219 (48%), Gaps = 18/219 (8%) Query: 1024 SVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVN 1083 S M ++ SL++LTA + + K K KV +D +FGVPLTV Sbjct: 177 SAEDMKKIRHLSLIELTAFFDAFGIQLKRN---------KTEKVKG-RDNGIFGVPLTVL 226 Query: 1084 V-----QRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAI--DCV 1136 + + G +P +Q+ + L+ G+FR SG ++++ R+ + D Sbjct: 227 LDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKF 286 Query: 1137 NYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQ-RLQAIKAAIMLLPD 1195 ++ + A MLK +FR+LP L + F+ + + P + + QA+ +M LPD Sbjct: 287 KWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPD 346 Query: 1196 ENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLF 1234 NR+ Q L+ F + V A +N+M+ N++ +AP+LF Sbjct: 347 ANRDAAQALMTFFNKVIANESKNRMSLWNISTVMAPNLF 385 Score = 41.2 bits (95), Expect = 0.008 Identities = 40/156 (25%), Positives = 65/156 (41%), Gaps = 20/156 (12%) Query: 570 SHPKDGPSPGGTLMDLSERQEVS-------SVRSLSSTGSLPSHAPPSEDAATPRTNSVI 622 S P D TL D S+ +E S SV L + LP H+ S + P N++ Sbjct: 52 SMPDDASLNSTTLSDASQDKEGSFAVPRSDSVAILETIPVLPVHSNGSPEPGQPVQNAI- 110 Query: 623 SVCSSSNLAGNDDSFGSLPSPKELSSFSFSMKGHEKTAKSKTRSLLKRMESLKLKSSHHS 682 +DD F P E SF + E ++ R+ LK+ E K Sbjct: 111 ----------SDDDFLEKNIPPEAEELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTK 160 Query: 683 KHKAPSKLGLIISGPILQEGMDEEKLKQLNCVEISA 718 + ++ GL +G + E D +K++ L+ +E++A Sbjct: 161 FNVQKTRFGLTEAGDLSAE--DMKKIRHLSLIELTA 194 >gi|59710111 Rho GTPase activating protein 28 isoform b [Homo sapiens] Length = 563 Score = 83.6 bits (205), Expect = 1e-15 Identities = 61/219 (27%), Positives = 106/219 (48%), Gaps = 18/219 (8%) Query: 1024 SVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVN 1083 S M ++ SL++LTA + + K K KV +D +FGVPLTV Sbjct: 177 SAEDMKKIRHLSLIELTAFFDAFGIQLKRN---------KTEKVKG-RDNGIFGVPLTVL 226 Query: 1084 V-----QRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAI--DCV 1136 + + G +P +Q+ + L+ G+FR SG ++++ R+ + D Sbjct: 227 LDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKF 286 Query: 1137 NYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQ-RLQAIKAAIMLLPD 1195 ++ + A MLK +FR+LP L + F+ + + P + + QA+ +M LPD Sbjct: 287 KWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPD 346 Query: 1196 ENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLF 1234 NR+ Q L+ F + V A +N+M+ N++ +AP+LF Sbjct: 347 ANRDAAQALMTFFNKVIANESKNRMSLWNISTVMAPNLF 385 Score = 41.2 bits (95), Expect = 0.008 Identities = 40/156 (25%), Positives = 65/156 (41%), Gaps = 20/156 (12%) Query: 570 SHPKDGPSPGGTLMDLSERQEVS-------SVRSLSSTGSLPSHAPPSEDAATPRTNSVI 622 S P D TL D S+ +E S SV L + LP H+ S + P N++ Sbjct: 52 SMPDDASLNSTTLSDASQDKEGSFAVPRSDSVAILETIPVLPVHSNGSPEPGQPVQNAI- 110 Query: 623 SVCSSSNLAGNDDSFGSLPSPKELSSFSFSMKGHEKTAKSKTRSLLKRMESLKLKSSHHS 682 +DD F P E SF + E ++ R+ LK+ E K Sbjct: 111 ----------SDDDFLEKNIPPEAEELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTK 160 Query: 683 KHKAPSKLGLIISGPILQEGMDEEKLKQLNCVEISA 718 + ++ GL +G + E D +K++ L+ +E++A Sbjct: 161 FNVQKTRFGLTEAGDLSAE--DMKKIRHLSLIELTA 194 >gi|40255080 hypothetical protein LOC158763 [Homo sapiens] Length = 547 Score = 83.2 bits (204), Expect = 2e-15 Identities = 61/229 (26%), Positives = 108/229 (47%), Gaps = 24/229 (10%) Query: 1075 VFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAID 1134 + G +++ + +PQ ++ +++ H L VG+F R++ LR+ + +D Sbjct: 219 LLGSKRKMSLNPIAKQIPQVVEACCQFIEKHGLSAVGIFTLEYSVQRVRQLREEFDQGLD 278 Query: 1135 CVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLP 1194 V + Q+ +DVA +LK++FRD+ + L+ + L +FL P+DQ L A++ + L+P Sbjct: 279 VVLDDNQNVHDVAALLKEFFRDMKDSLLPDDLYMSFLLTATLKPQDQ-LSALQLLVYLMP 337 Query: 1195 DENREVLQTLLYFLSDVT-----------AAVKENQMTPTNLAVCLAPSLFHLNTLKREN 1243 + + L+ LL L +T V N+MT TNLA+ +L + Sbjct: 338 PCHSDTLERLLKALHKITENCEDSIGIDGQLVPGNRMTSTNLALVFGSALLKKGKFGKRE 397 Query: 1244 SSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEMSR 1292 S RK LG ++ +A+ + MI LFQVP + R Sbjct: 398 S------RKTKLG------IDHYVASVNVVRAMIDNWDVLFQVPPHIQR 434 >gi|85815829 SH3-domain binding protein 1 [Homo sapiens] Length = 701 Score = 83.2 bits (204), Expect = 2e-15 Identities = 50/159 (31%), Positives = 83/159 (52%) Query: 1075 VFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAID 1134 V+GV L ++Q G+ + I+ + L + + + GLFR + S ++ L+Q Sbjct: 273 VYGVSLATHLQELGREIALPIEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMASDPH 332 Query: 1135 CVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLP 1194 + + VA LK Y R+LPEPLMT L + +++ RLQA++ LP Sbjct: 333 SLEEFCSDPHAVAGALKSYLRELPEPLMTFDLYDDWMRAASLKEPGARLQALQEVCSRLP 392 Query: 1195 DENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSL 1233 EN L+ L+ FL+ + + N+MTP+N+A+ L P+L Sbjct: 393 PENLSNLRYLMKFLARLAEEQEVNKMTPSNIAIVLGPNL 431 >gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens] Length = 1444 Score = 82.8 bits (203), Expect = 2e-15 Identities = 52/164 (31%), Positives = 85/164 (51%), Gaps = 6/164 (3%) Query: 1074 SVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAI 1133 S FG LT ++ +GQ +P ++ ++ H + G++R SGV S IQ LRQ G+ Sbjct: 17 SAFGCDLTEYLESSGQDVPYVLKSCAEFIETHGIVD-GIYRLSGVTSNIQRLRQ-EFGSD 74 Query: 1134 DCVNYEG----QSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAA 1189 C + Q + V + K YFR+LP PL+T +L E F + + P++ +L I+ Sbjct: 75 QCPDLTREVYLQDIHCVGSLCKLYFRELPNPLLTYELYEKFTEAVSHCPEEGQLARIQNV 134 Query: 1190 IMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSL 1233 I LP + L+ L+ L+ + + + M NLA+ AP+L Sbjct: 135 IQELPPSHYRTLEYLIRHLAHIASFSSKTNMHARNLALVWAPNL 178 Score = 31.2 bits (69), Expect = 8.0 Identities = 19/91 (20%), Positives = 43/91 (47%), Gaps = 4/91 (4%) Query: 369 IENALSTSSSPSGTPTNLRRHVPDLESGSESGADTISVNQTRVNLSSDTESTDLPSSTPV 428 + +ST+S+P TP + + LE S G+++ + L ++T + +P + Sbjct: 498 VSAVISTNSTPCRTPPKELQSLSSLEEFSFHGSESGGWPEEEKPLGAETSAASVPKKAGL 557 Query: 429 ANSGTKPKTTAI----QGISEKEKAEIEAKE 455 ++ P+ +G+S++ A +E K+ Sbjct: 558 EDAKAVPEAPGTVECSKGLSQEPGAHLEEKK 588 >gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo sapiens] Length = 1499 Score = 82.0 bits (201), Expect = 4e-15 Identities = 49/163 (30%), Positives = 90/163 (55%), Gaps = 2/163 (1%) Query: 1072 DRSVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQAL-RQMNE 1130 + + FGVPLT V +P+P I++ + Y+ L G++R SG KS +++L RQ ++ Sbjct: 1243 ESNYFGVPLTT-VVTPEKPIPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQ 1301 Query: 1131 GAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAI 1190 + + + VA +K +F +LP+PL+ + ++ ++ ++Q+L A+K + Sbjct: 1302 DHNLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVL 1361 Query: 1191 MLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSL 1233 P EN EV + ++ L+ V+ K N MT NL++C P+L Sbjct: 1362 KKFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTL 1404 >gi|5803145 ralA binding protein 1 [Homo sapiens] Length = 655 Score = 82.0 bits (201), Expect = 4e-15 Identities = 51/174 (29%), Positives = 92/174 (52%), Gaps = 7/174 (4%) Query: 1064 RIKVPDYKDRSVFGVPLTVNVQRT----GQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVK 1119 +I VP+ K +FG+PL V+RT G LP ++ + Y+ + + G++R SG+K Sbjct: 180 QIDVPNLKP--IFGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGIK 237 Query: 1120 SRIQALRQMNEGAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPK 1179 S++ L+ + + N E VA +LKQY RDLPE L+T +L F + + Sbjct: 238 SKVDELKAAYDRE-ESTNLEDYEPNTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTE 296 Query: 1180 DQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSL 1233 +++Q + + LP+ N ++ L+ + V A E +M N+++ L+P++ Sbjct: 297 TEKVQEFQRLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTV 350 >gi|194272142 myosin IXB isoform 2 [Homo sapiens] Length = 2022 Score = 82.0 bits (201), Expect = 4e-15 Identities = 51/156 (32%), Positives = 80/156 (51%), Gaps = 4/156 (2%) Query: 1091 LPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADML 1150 +P +++ + ++ H L GL+RKSG +R + LRQ + V E + + +L Sbjct: 1712 VPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDPAAVKLENFPIHAITGVL 1771 Query: 1151 KQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSD 1210 KQ+ R+LPEPLMT FL+ + K ++L AI A + LP+ N L+ L++ L Sbjct: 1772 KQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHLPEANHNSLERLIFHLVK 1831 Query: 1211 VTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSP 1246 V N+M+P LA+ AP L +NS P Sbjct: 1832 VALLEDVNRMSPGALAIIFAPCLLRC----PDNSDP 1863 >gi|33356170 myosin IXB isoform 1 [Homo sapiens] Length = 2157 Score = 82.0 bits (201), Expect = 4e-15 Identities = 51/156 (32%), Positives = 80/156 (51%), Gaps = 4/156 (2%) Query: 1091 LPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADML 1150 +P +++ + ++ H L GL+RKSG +R + LRQ + V E + + +L Sbjct: 1712 VPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDPAAVKLENFPIHAITGVL 1771 Query: 1151 KQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSD 1210 KQ+ R+LPEPLMT FL+ + K ++L AI A + LP+ N L+ L++ L Sbjct: 1772 KQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHLPEANHNSLERLIFHLVK 1831 Query: 1211 VTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSP 1246 V N+M+P LA+ AP L +NS P Sbjct: 1832 VALLEDVNRMSPGALAIIFAPCLLRC----PDNSDP 1863 >gi|156071465 Rho GTPase activating protein 4 [Homo sapiens] Length = 946 Score = 81.6 bits (200), Expect = 5e-15 Identities = 53/165 (32%), Positives = 84/165 (50%), Gaps = 4/165 (2%) Query: 1072 DRSVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEG 1131 ++ +FG + +Q +GQP+P ++ +R++ + L G+FR SG + R+ +R E Sbjct: 501 NQRLFGGDMEKFIQSSGQPVPLVVESCIRFINLNGLQHEGIFRVSGAQLRVSEIRDAFER 560 Query: 1132 AIDCVNYEGQSAYD---VADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKA 1188 D + EG +A+D VA +LK YFR L PL L L + +R++ + Sbjct: 561 GEDPL-VEGCTAHDLDSVAGVLKLYFRSLEPPLFPPDLFGELLASSELEATAERVEHVSR 619 Query: 1189 AIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSL 1233 + LP VL+ L FL+ + EN M P NLAVC P+L Sbjct: 620 LLWRLPAPVLVVLRYLFTFLNHLAQYSDENMMDPYNLAVCFGPTL 664 >gi|26986534 Rho GTPase activating protein 12 [Homo sapiens] Length = 846 Score = 79.3 bits (194), Expect = 3e-14 Identities = 56/205 (27%), Positives = 101/205 (49%), Gaps = 4/205 (1%) Query: 1031 LQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTGQP 1090 L+ + + + + +K T N F P ++ ++ Y VFG L QR Sbjct: 610 LRSFKVSSIDSSEQKKTKKNLKKFLTRRPT-LQAVREKGYIKDQVFGSNLANLCQRENGT 668 Query: 1091 LPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQM--NEGAIDCVNYEGQSAYDVAD 1148 +P+ ++ + ++ H LD G++R SG + IQ LR ++ +D + + + + + Sbjct: 669 VPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVITG 728 Query: 1149 MLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFL 1208 LK +FR+LPEPL T F+ + P+ QR+ A+K I LP N++ +Q L L Sbjct: 729 ALKMFFRELPEPLFTFNHFNDFVNAIKQEPR-QRVAAVKDLIRQLPKPNQDTMQILFRHL 787 Query: 1209 SDVTAAVKENQMTPTNLAVCLAPSL 1233 V ++N+MT ++A+ P+L Sbjct: 788 RRVIENGEKNRMTYQSIAIVFGPTL 812 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.312 0.129 0.372 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 61,012,689 Number of Sequences: 37866 Number of extensions: 2930875 Number of successful extensions: 9995 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 109 Number of HSP's successfully gapped in prelim test: 140 Number of HSP's that attempted gapping in prelim test: 9333 Number of HSP's gapped (non-prelim): 650 length of query: 1528 length of database: 18,247,518 effective HSP length: 115 effective length of query: 1413 effective length of database: 13,892,928 effective search space: 19630707264 effective search space used: 19630707264 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.