Guide to the Human Genome
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Search of human proteins with 33188433

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens]
         (1528 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens]       3064   0.0  
gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens]       2168   0.0  
gi|41281907 StAR-related lipid transfer (START) domain containin...  1102   0.0  
gi|41281898 StAR-related lipid transfer (START) domain containin...  1101   0.0  
gi|16445031 StAR-related lipid transfer (START) domain containin...   999   0.0  
gi|33188435 deleted in liver cancer 1 isoform 3 [Homo sapiens]        898   0.0  
gi|215820652 StAR-related lipid transfer (START) domain containi...   653   0.0  
gi|215820650 StAR-related lipid transfer (START) domain containi...   653   0.0  
gi|31543659 StAR-related lipid transfer (START) domain containin...   653   0.0  
gi|39932589 Rho GTPase activating protein 18 [Homo sapiens]            99   2e-20
gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens]    92   5e-18
gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo sapi...    92   5e-18
gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo sapi...    92   5e-18
gi|239757488 PREDICTED: chromosome 20 open reading frame 95 [Hom...    88   6e-17
gi|239752003 PREDICTED: chromosome 20 open reading frame 95 [Hom...    88   6e-17
gi|239746488 PREDICTED: Rho GTPase-activating protein 18-like [H...    88   6e-17
gi|54860079 nadrin isoform 1 [Homo sapiens]                            88   6e-17
gi|54860105 nadrin isoform 2 [Homo sapiens]                            88   6e-17
gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]        85   6e-16
gi|59710113 Rho GTPase activating protein 28 isoform a [Homo sap...    84   1e-15
gi|59710111 Rho GTPase activating protein 28 isoform b [Homo sap...    84   1e-15
gi|40255080 hypothetical protein LOC158763 [Homo sapiens]              83   2e-15
gi|85815829 SH3-domain binding protein 1 [Homo sapiens]                83   2e-15
gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens]            83   2e-15
gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo ...    82   4e-15
gi|5803145 ralA binding protein 1 [Homo sapiens]                       82   4e-15
gi|194272142 myosin IXB isoform 2 [Homo sapiens]                       82   4e-15
gi|33356170 myosin IXB isoform 1 [Homo sapiens]                        82   4e-15
gi|156071465 Rho GTPase activating protein 4 [Homo sapiens]            82   5e-15
gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]            79   3e-14

>gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens]
          Length = 1528

 Score = 3064 bits (7943), Expect = 0.0
 Identities = 1528/1528 (100%), Positives = 1528/1528 (100%)

Query: 1    MSVAIRKRSWEEHVTHWMGQPFNSDDRNTACHHGLVADSLQASMEKDATLNVDRKEKCVS 60
            MSVAIRKRSWEEHVTHWMGQPFNSDDRNTACHHGLVADSLQASMEKDATLNVDRKEKCVS
Sbjct: 1    MSVAIRKRSWEEHVTHWMGQPFNSDDRNTACHHGLVADSLQASMEKDATLNVDRKEKCVS 60

Query: 61   LPDCCHGSELRDFPGRPMGHLSKDVDENDSHEGEDQFLSLEASTETLVHVSDEDNNADLC 120
            LPDCCHGSELRDFPGRPMGHLSKDVDENDSHEGEDQFLSLEASTETLVHVSDEDNNADLC
Sbjct: 61   LPDCCHGSELRDFPGRPMGHLSKDVDENDSHEGEDQFLSLEASTETLVHVSDEDNNADLC 120

Query: 121  LTDDKQVLNTQGQKTSGQHMIQGAGSLEKALPIIQSNQVSSNSWGIAGETELALVKESGE 180
            LTDDKQVLNTQGQKTSGQHMIQGAGSLEKALPIIQSNQVSSNSWGIAGETELALVKESGE
Sbjct: 121  LTDDKQVLNTQGQKTSGQHMIQGAGSLEKALPIIQSNQVSSNSWGIAGETELALVKESGE 180

Query: 181  RKVTDSISKSLELCNEISLSEIKDAPKVNAVDTLNVKDIAPEKQLLNSAVIAQQRRKPDP 240
            RKVTDSISKSLELCNEISLSEIKDAPKVNAVDTLNVKDIAPEKQLLNSAVIAQQRRKPDP
Sbjct: 181  RKVTDSISKSLELCNEISLSEIKDAPKVNAVDTLNVKDIAPEKQLLNSAVIAQQRRKPDP 240

Query: 241  PKDENERSTCNVVQDEFLDTPCTNRGLPLLKTDFGSCLLQPPSCPNGMSAENGLEKSGFS 300
            PKDENERSTCNVVQDEFLDTPCTNRGLPLLKTDFGSCLLQPPSCPNGMSAENGLEKSGFS
Sbjct: 241  PKDENERSTCNVVQDEFLDTPCTNRGLPLLKTDFGSCLLQPPSCPNGMSAENGLEKSGFS 300

Query: 301  QHQNKSPPKVKAEDGMQCLQLKETLATQEPTDNQVRLRKRKEIREDRDRARLDSMVLLIM 360
            QHQNKSPPKVKAEDGMQCLQLKETLATQEPTDNQVRLRKRKEIREDRDRARLDSMVLLIM
Sbjct: 301  QHQNKSPPKVKAEDGMQCLQLKETLATQEPTDNQVRLRKRKEIREDRDRARLDSMVLLIM 360

Query: 361  KLDQLDQDIENALSTSSSPSGTPTNLRRHVPDLESGSESGADTISVNQTRVNLSSDTEST 420
            KLDQLDQDIENALSTSSSPSGTPTNLRRHVPDLESGSESGADTISVNQTRVNLSSDTEST
Sbjct: 361  KLDQLDQDIENALSTSSSPSGTPTNLRRHVPDLESGSESGADTISVNQTRVNLSSDTEST 420

Query: 421  DLPSSTPVANSGTKPKTTAIQGISEKEKAEIEAKEACDWLRATGFPQYAQLYEDFLFPID 480
            DLPSSTPVANSGTKPKTTAIQGISEKEKAEIEAKEACDWLRATGFPQYAQLYEDFLFPID
Sbjct: 421  DLPSSTPVANSGTKPKTTAIQGISEKEKAEIEAKEACDWLRATGFPQYAQLYEDFLFPID 480

Query: 481  ISLVKREHDFLDRDAIEALCRRLNTLNKCAVMKLEISPHRKRSDDSDEDEPCAISGKWTF 540
            ISLVKREHDFLDRDAIEALCRRLNTLNKCAVMKLEISPHRKRSDDSDEDEPCAISGKWTF
Sbjct: 481  ISLVKREHDFLDRDAIEALCRRLNTLNKCAVMKLEISPHRKRSDDSDEDEPCAISGKWTF 540

Query: 541  QRDSKRWSRLEEFDVFSPKQDLVPGSPDDSHPKDGPSPGGTLMDLSERQEVSSVRSLSST 600
            QRDSKRWSRLEEFDVFSPKQDLVPGSPDDSHPKDGPSPGGTLMDLSERQEVSSVRSLSST
Sbjct: 541  QRDSKRWSRLEEFDVFSPKQDLVPGSPDDSHPKDGPSPGGTLMDLSERQEVSSVRSLSST 600

Query: 601  GSLPSHAPPSEDAATPRTNSVISVCSSSNLAGNDDSFGSLPSPKELSSFSFSMKGHEKTA 660
            GSLPSHAPPSEDAATPRTNSVISVCSSSNLAGNDDSFGSLPSPKELSSFSFSMKGHEKTA
Sbjct: 601  GSLPSHAPPSEDAATPRTNSVISVCSSSNLAGNDDSFGSLPSPKELSSFSFSMKGHEKTA 660

Query: 661  KSKTRSLLKRMESLKLKSSHHSKHKAPSKLGLIISGPILQEGMDEEKLKQLNCVEISALN 720
            KSKTRSLLKRMESLKLKSSHHSKHKAPSKLGLIISGPILQEGMDEEKLKQLNCVEISALN
Sbjct: 661  KSKTRSLLKRMESLKLKSSHHSKHKAPSKLGLIISGPILQEGMDEEKLKQLNCVEISALN 720

Query: 721  GNRINVPMVRKRSVSNSTQTSSSSSQSETSSAVSTPSPVTRTRSLSACNKRVGMYLEGFD 780
            GNRINVPMVRKRSVSNSTQTSSSSSQSETSSAVSTPSPVTRTRSLSACNKRVGMYLEGFD
Sbjct: 721  GNRINVPMVRKRSVSNSTQTSSSSSQSETSSAVSTPSPVTRTRSLSACNKRVGMYLEGFD 780

Query: 781  PFNQSTFNNVVEQNFKNRESYPEDTVFYIPEDHKPGTFPKALTNGSFSPSGNNGSVNWRT 840
            PFNQSTFNNVVEQNFKNRESYPEDTVFYIPEDHKPGTFPKALTNGSFSPSGNNGSVNWRT
Sbjct: 781  PFNQSTFNNVVEQNFKNRESYPEDTVFYIPEDHKPGTFPKALTNGSFSPSGNNGSVNWRT 840

Query: 841  GSFHGPGHISLRRENSSDSPKELKRRNSSSSMSSRLSIYDNVPGSILYSSSGDLADLENE 900
            GSFHGPGHISLRRENSSDSPKELKRRNSSSSMSSRLSIYDNVPGSILYSSSGDLADLENE
Sbjct: 841  GSFHGPGHISLRRENSSDSPKELKRRNSSSSMSSRLSIYDNVPGSILYSSSGDLADLENE 900

Query: 901  DIFPELDDILYHVKGMQRIVNQWSEKFSDEGDSDSALDSVSPCPSSPKQIHLDVDNDRTT 960
            DIFPELDDILYHVKGMQRIVNQWSEKFSDEGDSDSALDSVSPCPSSPKQIHLDVDNDRTT
Sbjct: 901  DIFPELDDILYHVKGMQRIVNQWSEKFSDEGDSDSALDSVSPCPSSPKQIHLDVDNDRTT 960

Query: 961  PSDLDSTGNSLNEPEEPSEIPERRDSGVGASLTRSNRHRLRWHSFQSSHRPSLNSVSLQI 1020
            PSDLDSTGNSLNEPEEPSEIPERRDSGVGASLTRSNRHRLRWHSFQSSHRPSLNSVSLQI
Sbjct: 961  PSDLDSTGNSLNEPEEPSEIPERRDSGVGASLTRSNRHRLRWHSFQSSHRPSLNSVSLQI 1020

Query: 1021 NCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPL 1080
            NCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPL
Sbjct: 1021 NCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPL 1080

Query: 1081 TVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEG 1140
            TVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEG
Sbjct: 1081 TVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEG 1140

Query: 1141 QSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREV 1200
            QSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREV
Sbjct: 1141 QSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREV 1200

Query: 1201 LQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQ 1260
            LQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQ
Sbjct: 1201 LQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQ 1260

Query: 1261 KDLNENLAATQGLAHMIAECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGHLGNDDSAD 1320
            KDLNENLAATQGLAHMIAECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGHLGNDDSAD
Sbjct: 1261 KDLNENLAATQGLAHMIAECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGHLGNDDSAD 1320

Query: 1321 YQHFLQDCVDGLFKEVKEKFKGWVSYSTSEQAELSYKKVSEGPPLRLWRSVIEVPAVPEE 1380
            YQHFLQDCVDGLFKEVKEKFKGWVSYSTSEQAELSYKKVSEGPPLRLWRSVIEVPAVPEE
Sbjct: 1321 YQHFLQDCVDGLFKEVKEKFKGWVSYSTSEQAELSYKKVSEGPPLRLWRSVIEVPAVPEE 1380

Query: 1381 ILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPKG 1440
            ILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPKG
Sbjct: 1381 ILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPKG 1440

Query: 1441 ACALLLTSVDHDRAPVVGVRVNVLLSRYLIEPCGPGKSKLTYMCRVDLRGHMPEWYTKSF 1500
            ACALLLTSVDHDRAPVVGVRVNVLLSRYLIEPCGPGKSKLTYMCRVDLRGHMPEWYTKSF
Sbjct: 1441 ACALLLTSVDHDRAPVVGVRVNVLLSRYLIEPCGPGKSKLTYMCRVDLRGHMPEWYTKSF 1500

Query: 1501 GHLCAAEVVKIRDSFSNQNTETKDTKSR 1528
            GHLCAAEVVKIRDSFSNQNTETKDTKSR
Sbjct: 1501 GHLCAAEVVKIRDSFSNQNTETKDTKSR 1528


>gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens]
          Length = 1091

 Score = 2168 bits (5618), Expect = 0.0
 Identities = 1078/1079 (99%), Positives = 1079/1079 (100%)

Query: 450  EIEAKEACDWLRATGFPQYAQLYEDFLFPIDISLVKREHDFLDRDAIEALCRRLNTLNKC 509
            +IEAKEACDWLRATGFPQYAQLYEDFLFPIDISLVKREHDFLDRDAIEALCRRLNTLNKC
Sbjct: 13   QIEAKEACDWLRATGFPQYAQLYEDFLFPIDISLVKREHDFLDRDAIEALCRRLNTLNKC 72

Query: 510  AVMKLEISPHRKRSDDSDEDEPCAISGKWTFQRDSKRWSRLEEFDVFSPKQDLVPGSPDD 569
            AVMKLEISPHRKRSDDSDEDEPCAISGKWTFQRDSKRWSRLEEFDVFSPKQDLVPGSPDD
Sbjct: 73   AVMKLEISPHRKRSDDSDEDEPCAISGKWTFQRDSKRWSRLEEFDVFSPKQDLVPGSPDD 132

Query: 570  SHPKDGPSPGGTLMDLSERQEVSSVRSLSSTGSLPSHAPPSEDAATPRTNSVISVCSSSN 629
            SHPKDGPSPGGTLMDLSERQEVSSVRSLSSTGSLPSHAPPSEDAATPRTNSVISVCSSSN
Sbjct: 133  SHPKDGPSPGGTLMDLSERQEVSSVRSLSSTGSLPSHAPPSEDAATPRTNSVISVCSSSN 192

Query: 630  LAGNDDSFGSLPSPKELSSFSFSMKGHEKTAKSKTRSLLKRMESLKLKSSHHSKHKAPSK 689
            LAGNDDSFGSLPSPKELSSFSFSMKGHEKTAKSKTRSLLKRMESLKLKSSHHSKHKAPSK
Sbjct: 193  LAGNDDSFGSLPSPKELSSFSFSMKGHEKTAKSKTRSLLKRMESLKLKSSHHSKHKAPSK 252

Query: 690  LGLIISGPILQEGMDEEKLKQLNCVEISALNGNRINVPMVRKRSVSNSTQTSSSSSQSET 749
            LGLIISGPILQEGMDEEKLKQLNCVEISALNGNRINVPMVRKRSVSNSTQTSSSSSQSET
Sbjct: 253  LGLIISGPILQEGMDEEKLKQLNCVEISALNGNRINVPMVRKRSVSNSTQTSSSSSQSET 312

Query: 750  SSAVSTPSPVTRTRSLSACNKRVGMYLEGFDPFNQSTFNNVVEQNFKNRESYPEDTVFYI 809
            SSAVSTPSPVTRTRSLSACNKRVGMYLEGFDPFNQSTFNNVVEQNFKNRESYPEDTVFYI
Sbjct: 313  SSAVSTPSPVTRTRSLSACNKRVGMYLEGFDPFNQSTFNNVVEQNFKNRESYPEDTVFYI 372

Query: 810  PEDHKPGTFPKALTNGSFSPSGNNGSVNWRTGSFHGPGHISLRRENSSDSPKELKRRNSS 869
            PEDHKPGTFPKALTNGSFSPSGNNGSVNWRTGSFHGPGHISLRRENSSDSPKELKRRNSS
Sbjct: 373  PEDHKPGTFPKALTNGSFSPSGNNGSVNWRTGSFHGPGHISLRRENSSDSPKELKRRNSS 432

Query: 870  SSMSSRLSIYDNVPGSILYSSSGDLADLENEDIFPELDDILYHVKGMQRIVNQWSEKFSD 929
            SSMSSRLSIYDNVPGSILYSSSGDLADLENEDIFPELDDILYHVKGMQRIVNQWSEKFSD
Sbjct: 433  SSMSSRLSIYDNVPGSILYSSSGDLADLENEDIFPELDDILYHVKGMQRIVNQWSEKFSD 492

Query: 930  EGDSDSALDSVSPCPSSPKQIHLDVDNDRTTPSDLDSTGNSLNEPEEPSEIPERRDSGVG 989
            EGDSDSALDSVSPCPSSPKQIHLDVDNDRTTPSDLDSTGNSLNEPEEPSEIPERRDSGVG
Sbjct: 493  EGDSDSALDSVSPCPSSPKQIHLDVDNDRTTPSDLDSTGNSLNEPEEPSEIPERRDSGVG 552

Query: 990  ASLTRSNRHRLRWHSFQSSHRPSLNSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPS 1049
            ASLTRSNRHRLRWHSFQSSHRPSLNSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPS
Sbjct: 553  ASLTRSNRHRLRWHSFQSSHRPSLNSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPS 612

Query: 1050 NKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQ 1109
            NKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQ
Sbjct: 613  NKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQ 672

Query: 1110 VGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSET 1169
            VGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSET
Sbjct: 673  VGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSET 732

Query: 1170 FLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCL 1229
            FLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCL
Sbjct: 733  FLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCL 792

Query: 1230 APSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEE 1289
            APSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEE
Sbjct: 793  APSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEE 852

Query: 1290 MSRCRNSYTEQELKPLTLEALGHLGNDDSADYQHFLQDCVDGLFKEVKEKFKGWVSYSTS 1349
            MSRCRNSYTEQELKPLTLEALGHLGNDDSADYQHFLQDCVDGLFKEVKEKFKGWVSYSTS
Sbjct: 853  MSRCRNSYTEQELKPLTLEALGHLGNDDSADYQHFLQDCVDGLFKEVKEKFKGWVSYSTS 912

Query: 1350 EQAELSYKKVSEGPPLRLWRSVIEVPAVPEEILKRLLKEQHLWDVDLLDSKVIEILDSQT 1409
            EQAELSYKKVSEGPPLRLWRSVIEVPAVPEEILKRLLKEQHLWDVDLLDSKVIEILDSQT
Sbjct: 913  EQAELSYKKVSEGPPLRLWRSVIEVPAVPEEILKRLLKEQHLWDVDLLDSKVIEILDSQT 972

Query: 1410 EIYQYVQNSMAPHPARDYVVLRTWRTNLPKGACALLLTSVDHDRAPVVGVRVNVLLSRYL 1469
            EIYQYVQNSMAPHPARDYVVLRTWRTNLPKGACALLLTSVDHDRAPVVGVRVNVLLSRYL
Sbjct: 973  EIYQYVQNSMAPHPARDYVVLRTWRTNLPKGACALLLTSVDHDRAPVVGVRVNVLLSRYL 1032

Query: 1470 IEPCGPGKSKLTYMCRVDLRGHMPEWYTKSFGHLCAAEVVKIRDSFSNQNTETKDTKSR 1528
            IEPCGPGKSKLTYMCRVDLRGHMPEWYTKSFGHLCAAEVVKIRDSFSNQNTETKDTKSR
Sbjct: 1033 IEPCGPGKSKLTYMCRVDLRGHMPEWYTKSFGHLCAAEVVKIRDSFSNQNTETKDTKSR 1091


>gi|41281907 StAR-related lipid transfer (START) domain containing 13
            isoform beta [Homo sapiens]
          Length = 1105

 Score = 1102 bits (2849), Expect = 0.0
 Identities = 606/1096 (55%), Positives = 776/1096 (70%), Gaps = 53/1096 (4%)

Query: 447  EKAEIEAKEACDWLRATGFPQYAQLYEDFLFPIDISLVKREHDFLDRDAIEALCRRLNTL 506
            ++ EIEAKEACDWLRA GFPQYAQLYED  FPI+I  VK +HDFL++D +E LCRRLNTL
Sbjct: 46   QRREIEAKEACDWLRAAGFPQYAQLYEDSQFPINIVAVKNDHDFLEKDLVEPLCRRLNTL 105

Query: 507  NKCAVMKLEISPHRKRSDDSDEDEPCAISGKWTFQRDSKRWSRLEEFDVFSPKQDLVPGS 566
            NKCA MKL+++  RK+ DDSDE++ C IS KWTFQR S+RWSR+++     P+ D   GS
Sbjct: 106  NKCASMKLDVNFQRKKGDDSDEEDLC-ISNKWTFQRTSRRWSRVDDLYTLLPRGDR-NGS 163

Query: 567  PDDSHPKDGPSPGGTLMDLSERQEVSSVRSLSSTGSLPSHAPPSEDAATPRTNSVISVCS 626
            P  +  ++  S    L DLSE  EV S+ S SS GS  S + P +             C 
Sbjct: 164  PGGTGMRNTTSSESVLTDLSE-PEVCSIHSESSGGS-DSRSQPGQ-------------CC 208

Query: 627  SSNLAGNDDSF--GSLPSP-KELSSFSFSMKGHEKTAKSKTRSLLKRMESLKLKSSHHSK 683
            + N    D      SLP P +++ +  F  K +EK  +++ +S LKRME+L+ K +H  +
Sbjct: 209  TDNPVMLDAPLVSSSLPQPPRDVLNHPFHPK-NEKPTRARAKSFLKRMETLRGKGAH-GR 266

Query: 684  HKAPSKLG-LIISGPILQEGMDEEKLKQLNCVEISALNGNRINVPMVR-KRSVSNSTQTS 741
            HK   + G L+ISGP+LQ+  + E  K + C++I   NG+  N P    ++ +  S ++S
Sbjct: 267  HKGSGRTGGLVISGPMLQQ--EPESFKAMQCIQIP--NGDLQNSPPPACRKGLPCSGKSS 322

Query: 742  SSSSQSE-TSSAVSTPSPVTRTRSLSACNKRVGMYLEGFDPFNQSTFNNVVEQNFKNRES 800
              SS SE +SS VSTP    + R     NKR GMYLE  D    +   +  +Q+  +   
Sbjct: 323  GESSPSEHSSSGVSTPC--LKERKCHEANKRGGMYLEDLDVLAGTALPDAGDQSRMHEFH 380

Query: 801  YPEDTVFYIPEDHKPGTFPKALTNGSFSPSGNNGSVNWRTGSFHGPGHISLRRENSSDSP 860
              E+ V +IP+DHKPGTFPKAL+  S SP+ ++  VNWRTGS      ISL RE    + 
Sbjct: 381  SQENLVVHIPKDHKPGTFPKALSIESLSPTDSSNGVNWRTGS------ISLGREQVPGAR 434

Query: 861  KELKRRNSSSSMSSRLSIYDNVPGSILYSSSGDLADLENEDIFPELDDILYHVKGMQRIV 920
            +   R  +S   +SR+SIYDNVPGS LY+S+GDL DLE +D+FP LDDIL HV G+Q +V
Sbjct: 435  EP--RLMASCHRASRVSIYDNVPGSHLYASTGDLLDLEKDDLFPHLDDILQHVNGLQEVV 492

Query: 921  NQWSEKFSDEGDSDSAL---DSVSPCPSSPKQIHLD-----VDNDRTTPSDLDSTGNSLN 972
            + WS+    E  +   L     +S  PS P QI LD     V   RTTPSD++    SLN
Sbjct: 493  DDWSKDVLPELQTHDTLVGEPGLSTFPS-PNQITLDFEGNSVSEGRTTPSDVERDVTSLN 551

Query: 973  EPEEPSEIPERRDSGVGASLTRSNRHRLRWHSFQSSHRPSLNSVSLQINCQSVAQMNLLQ 1032
            E E P  + +RRDSGVGASLTR NR RLRW+SFQ SH+P     S  I+ Q+ +Q++LLQ
Sbjct: 552  ESEPPG-VRDRRDSGVGASLTRPNR-RLRWNSFQLSHQPRPAPASPHISSQTASQLSLLQ 609

Query: 1033 KYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTGQPLP 1092
            ++SLL+LTA++EK++ SNKHG++W+VPKFMKR+KVPDYKD++VFGVPL V+VQRTGQPLP
Sbjct: 610  RFSLLRLTAIMEKHSMSNKHGWTWSVPKFMKRMKVPDYKDKAVFGVPLIVHVQRTGQPLP 669

Query: 1093 QSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADMLKQ 1152
            QSIQQA+RYLR++CLDQVGLFRKSGVKSRI ALRQMNE   + VNYE QSAYDVADM+KQ
Sbjct: 670  QSIQQALRYLRSNCLDQVGLFRKSGVKSRIHALRQMNENFPENVNYEDQSAYDVADMVKQ 729

Query: 1153 YFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVT 1212
            +FRDLPEPL TNKLSETFL IYQYV K+QRLQA++AAI+LL DENREVLQTLL FL+DV 
Sbjct: 730  FFRDLPEPLFTNKLSETFLHIYQYVSKEQRLQAVQAAILLLADENREVLQTLLCFLNDVV 789

Query: 1213 AAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQG 1272
              V+ENQMTP NLAVCLAPSLFHLN LK+E SSPRV+Q+K + GKPDQKDLNENLAA QG
Sbjct: 790  NLVEENQMTPMNLAVCLAPSLFHLNLLKKE-SSPRVIQKKYATGKPDQKDLNENLAAAQG 848

Query: 1273 LAHMIAECKKLFQVPEEM-SRCRNSYTEQELKPLTLEALGHLGNDDSADYQHFLQDCVDG 1331
            LAHMI EC +LF+VP E+ ++ RNSY E E+   TLE LG    +  A +  +L   + G
Sbjct: 849  LAHMIMECDRLFEVPHELVAQSRNSYVEAEIHVPTLEELGTQLEESGATFHTYLNHLIQG 908

Query: 1332 LFKEVKEKFKGWVSYSTSEQAELSYKKVSEGPPLRLWRSVIEVPAVPEEILKRLLKEQHL 1391
            L KE KEKFKGWV+ S+++  +L++KKV +G PL+LW++ +EV A P  +L R+L+E+HL
Sbjct: 909  LQKEAKEKFKGWVTCSSTDNTDLAFKKVGDGNPLKLWKASVEVEAPPSVVLNRVLRERHL 968

Query: 1392 WDVDLLDSKVIEILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPKGACALLLTSVDH 1451
            WD D +  KV+E LD QTEIYQYV NSMAPHP+RD+VVLRTW+T+LPKG C L+  SV+H
Sbjct: 969  WDEDFVQWKVVETLDRQTEIYQYVLNSMAPHPSRDFVVLRTWKTDLPKGMCTLVSLSVEH 1028

Query: 1452 DRAPVV-GVRVNVLLSRYLIEPCGPGKSKLTYMCRVDLRGHMPEWYTKSFGHLCAAEVVK 1510
            + A ++ GVR  V+ S+YLIEPCG GKS+LT++CR+DL+GH PEWY+K FGHLCAAEV +
Sbjct: 1029 EEAQLLGGVRAVVMDSQYLIEPCGSGKSRLTHICRIDLKGHSPEWYSKGFGHLCAAEVAR 1088

Query: 1511 IRDSFSNQNTETKDTK 1526
            IR+SF     E  +TK
Sbjct: 1089 IRNSFQPLIAEGPETK 1104


>gi|41281898 StAR-related lipid transfer (START) domain containing 13
            isoform alpha [Homo sapiens]
          Length = 1113

 Score = 1101 bits (2848), Expect = 0.0
 Identities = 607/1097 (55%), Positives = 776/1097 (70%), Gaps = 53/1097 (4%)

Query: 446  KEKAEIEAKEACDWLRATGFPQYAQLYEDFLFPIDISLVKREHDFLDRDAIEALCRRLNT 505
            K + EIEAKEACDWLRA GFPQYAQLYED  FPI+I  VK +HDFL++D +E LCRRLNT
Sbjct: 53   KIQQEIEAKEACDWLRAAGFPQYAQLYEDSQFPINIVAVKNDHDFLEKDLVEPLCRRLNT 112

Query: 506  LNKCAVMKLEISPHRKRSDDSDEDEPCAISGKWTFQRDSKRWSRLEEFDVFSPKQDLVPG 565
            LNKCA MKL+++  RK+ DDSDE++ C IS KWTFQR S+RWSR+++     P+ D   G
Sbjct: 113  LNKCASMKLDVNFQRKKGDDSDEEDLC-ISNKWTFQRTSRRWSRVDDLYTLLPRGDR-NG 170

Query: 566  SPDDSHPKDGPSPGGTLMDLSERQEVSSVRSLSSTGSLPSHAPPSEDAATPRTNSVISVC 625
            SP  +  ++  S    L DLSE  EV S+ S SS GS  S + P +             C
Sbjct: 171  SPGGTGMRNTTSSESVLTDLSE-PEVCSIHSESSGGS-DSRSQPGQ-------------C 215

Query: 626  SSSNLAGNDDSF--GSLPSP-KELSSFSFSMKGHEKTAKSKTRSLLKRMESLKLKSSHHS 682
             + N    D      SLP P +++ +  F  K +EK  +++ +S LKRME+L+ K +H  
Sbjct: 216  CTDNPVMLDAPLVSSSLPQPPRDVLNHPFHPK-NEKPTRARAKSFLKRMETLRGKGAH-G 273

Query: 683  KHKAPSKLG-LIISGPILQEGMDEEKLKQLNCVEISALNGNRINVPMVR-KRSVSNSTQT 740
            +HK   + G L+ISGP+LQ+  + E  K + C++I   NG+  N P    ++ +  S ++
Sbjct: 274  RHKGSGRTGGLVISGPMLQQ--EPESFKAMQCIQIP--NGDLQNSPPPACRKGLPCSGKS 329

Query: 741  SSSSSQSE-TSSAVSTPSPVTRTRSLSACNKRVGMYLEGFDPFNQSTFNNVVEQNFKNRE 799
            S  SS SE +SS VSTP    + R     NKR GMYLE  D    +   +  +Q+  +  
Sbjct: 330  SGESSPSEHSSSGVSTPC--LKERKCHEANKRGGMYLEDLDVLAGTALPDAGDQSRMHEF 387

Query: 800  SYPEDTVFYIPEDHKPGTFPKALTNGSFSPSGNNGSVNWRTGSFHGPGHISLRRENSSDS 859
               E+ V +IP+DHKPGTFPKAL+  S SP+ ++  VNWRTGS      ISL RE    +
Sbjct: 388  HSQENLVVHIPKDHKPGTFPKALSIESLSPTDSSNGVNWRTGS------ISLGREQVPGA 441

Query: 860  PKELKRRNSSSSMSSRLSIYDNVPGSILYSSSGDLADLENEDIFPELDDILYHVKGMQRI 919
             +   R  +S   +SR+SIYDNVPGS LY+S+GDL DLE +D+FP LDDIL HV G+Q +
Sbjct: 442  REP--RLMASCHRASRVSIYDNVPGSHLYASTGDLLDLEKDDLFPHLDDILQHVNGLQEV 499

Query: 920  VNQWSEKFSDEGDSDSAL---DSVSPCPSSPKQIHLD-----VDNDRTTPSDLDSTGNSL 971
            V+ WS+    E  +   L     +S  PS P QI LD     V   RTTPSD++    SL
Sbjct: 500  VDDWSKDVLPELQTHDTLVGEPGLSTFPS-PNQITLDFEGNSVSEGRTTPSDVERDVTSL 558

Query: 972  NEPEEPSEIPERRDSGVGASLTRSNRHRLRWHSFQSSHRPSLNSVSLQINCQSVAQMNLL 1031
            NE E P  + +RRDSGVGASLTR NR RLRW+SFQ SH+P     S  I+ Q+ +Q++LL
Sbjct: 559  NESEPPG-VRDRRDSGVGASLTRPNR-RLRWNSFQLSHQPRPAPASPHISSQTASQLSLL 616

Query: 1032 QKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTGQPL 1091
            Q++SLL+LTA++EK++ SNKHG++W+VPKFMKR+KVPDYKD++VFGVPL V+VQRTGQPL
Sbjct: 617  QRFSLLRLTAIMEKHSMSNKHGWTWSVPKFMKRMKVPDYKDKAVFGVPLIVHVQRTGQPL 676

Query: 1092 PQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADMLK 1151
            PQSIQQA+RYLR++CLDQVGLFRKSGVKSRI ALRQMNE   + VNYE QSAYDVADM+K
Sbjct: 677  PQSIQQALRYLRSNCLDQVGLFRKSGVKSRIHALRQMNENFPENVNYEDQSAYDVADMVK 736

Query: 1152 QYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDV 1211
            Q+FRDLPEPL TNKLSETFL IYQYV K+QRLQA++AAI+LL DENREVLQTLL FL+DV
Sbjct: 737  QFFRDLPEPLFTNKLSETFLHIYQYVSKEQRLQAVQAAILLLADENREVLQTLLCFLNDV 796

Query: 1212 TAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQ 1271
               V+ENQMTP NLAVCLAPSLFHLN LK+E SSPRV+Q+K + GKPDQKDLNENLAA Q
Sbjct: 797  VNLVEENQMTPMNLAVCLAPSLFHLNLLKKE-SSPRVIQKKYATGKPDQKDLNENLAAAQ 855

Query: 1272 GLAHMIAECKKLFQVPEEM-SRCRNSYTEQELKPLTLEALGHLGNDDSADYQHFLQDCVD 1330
            GLAHMI EC +LF+VP E+ ++ RNSY E E+   TLE LG    +  A +  +L   + 
Sbjct: 856  GLAHMIMECDRLFEVPHELVAQSRNSYVEAEIHVPTLEELGTQLEESGATFHTYLNHLIQ 915

Query: 1331 GLFKEVKEKFKGWVSYSTSEQAELSYKKVSEGPPLRLWRSVIEVPAVPEEILKRLLKEQH 1390
            GL KE KEKFKGWV+ S+++  +L++KKV +G PL+LW++ +EV A P  +L R+L+E+H
Sbjct: 916  GLQKEAKEKFKGWVTCSSTDNTDLAFKKVGDGNPLKLWKASVEVEAPPSVVLNRVLRERH 975

Query: 1391 LWDVDLLDSKVIEILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPKGACALLLTSVD 1450
            LWD D +  KV+E LD QTEIYQYV NSMAPHP+RD+VVLRTW+T+LPKG C L+  SV+
Sbjct: 976  LWDEDFVQWKVVETLDRQTEIYQYVLNSMAPHPSRDFVVLRTWKTDLPKGMCTLVSLSVE 1035

Query: 1451 HDRAPVV-GVRVNVLLSRYLIEPCGPGKSKLTYMCRVDLRGHMPEWYTKSFGHLCAAEVV 1509
            H+ A ++ GVR  V+ S+YLIEPCG GKS+LT++CR+DL+GH PEWY+K FGHLCAAEV 
Sbjct: 1036 HEEAQLLGGVRAVVMDSQYLIEPCGSGKSRLTHICRIDLKGHSPEWYSKGFGHLCAAEVA 1095

Query: 1510 KIRDSFSNQNTETKDTK 1526
            +IR+SF     E  +TK
Sbjct: 1096 RIRNSFQPLIAEGPETK 1112


>gi|16445031 StAR-related lipid transfer (START) domain containing 13
            isoform gamma [Homo sapiens]
          Length = 995

 Score =  999 bits (2583), Expect = 0.0
 Identities = 558/1031 (54%), Positives = 721/1031 (69%), Gaps = 53/1031 (5%)

Query: 512  MKLEISPHRKRSDDSDEDEPCAISGKWTFQRDSKRWSRLEEFDVFSPKQDLVPGSPDDSH 571
            MKL+++  RK+ DDSDE++ C IS KWTFQR S+RWSR+++     P+ D   GSP  + 
Sbjct: 1    MKLDVNFQRKKGDDSDEEDLC-ISNKWTFQRTSRRWSRVDDLYTLLPRGDR-NGSPGGTG 58

Query: 572  PKDGPSPGGTLMDLSERQEVSSVRSLSSTGSLPSHAPPSEDAATPRTNSVISVCSSSNLA 631
             ++  S    L DLSE  EV S+ S SS GS  S + P +             C + N  
Sbjct: 59   MRNTTSSESVLTDLSE-PEVCSIHSESSGGS-DSRSQPGQ-------------CCTDNPV 103

Query: 632  GNDDSF--GSLPSP-KELSSFSFSMKGHEKTAKSKTRSLLKRMESLKLKSSHHSKHKAPS 688
              D      SLP P +++ +  F  K +EK  +++ +S LKRME+L+ K +H  +HK   
Sbjct: 104  MLDAPLVSSSLPQPPRDVLNHPFHPK-NEKPTRARAKSFLKRMETLRGKGAH-GRHKGSG 161

Query: 689  KLG-LIISGPILQEGMDEEKLKQLNCVEISALNGNRINVPMVR-KRSVSNSTQTSSSSSQ 746
            + G L+ISGP+LQ+  + E  K + C++I   NG+  N P    ++ +  S ++S  SS 
Sbjct: 162  RTGGLVISGPMLQQ--EPESFKAMQCIQIP--NGDLQNSPPPACRKGLPCSGKSSGESSP 217

Query: 747  SE-TSSAVSTPSPVTRTRSLSACNKRVGMYLEGFDPFNQSTFNNVVEQNFKNRESYPEDT 805
            SE +SS VSTP    + R     NKR GMYLE  D    +   +  +Q+  +     E+ 
Sbjct: 218  SEHSSSGVSTPC--LKERKCHEANKRGGMYLEDLDVLAGTALPDAGDQSRMHEFHSQENL 275

Query: 806  VFYIPEDHKPGTFPKALTNGSFSPSGNNGSVNWRTGSFHGPGHISLRRENSSDSPKELKR 865
            V +IP+DHKPGTFPKAL+  S SP+ ++  VNWRTGS      ISL RE    + +   R
Sbjct: 276  VVHIPKDHKPGTFPKALSIESLSPTDSSNGVNWRTGS------ISLGREQVPGAREP--R 327

Query: 866  RNSSSSMSSRLSIYDNVPGSILYSSSGDLADLENEDIFPELDDILYHVKGMQRIVNQWSE 925
              +S   +SR+SIYDNVPGS LY+S+GDL DLE +D+FP LDDIL HV G+Q +V+ WS+
Sbjct: 328  LMASCHRASRVSIYDNVPGSHLYASTGDLLDLEKDDLFPHLDDILQHVNGLQEVVDDWSK 387

Query: 926  KFSDEGDSDSAL---DSVSPCPSSPKQIHLD-----VDNDRTTPSDLDSTGNSLNEPEEP 977
                E  +   L     +S  PS P QI LD     V   RTTPSD++    SLNE E P
Sbjct: 388  DVLPELQTHDTLVGEPGLSTFPS-PNQITLDFEGNSVSEGRTTPSDVERDVTSLNESEPP 446

Query: 978  SEIPERRDSGVGASLTRSNRHRLRWHSFQSSHRPSLNSVSLQINCQSVAQMNLLQKYSLL 1037
              + +RRDSGVGASLTR NR RLRW+SFQ SH+P     S  I+ Q+ +Q++LLQ++SLL
Sbjct: 447  G-VRDRRDSGVGASLTRPNR-RLRWNSFQLSHQPRPAPASPHISSQTASQLSLLQRFSLL 504

Query: 1038 KLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTGQPLPQSIQQ 1097
            +LTA++EK++ SNKHG++W+VPKFMKR+KVPDYKD++VFGVPL V+VQRTGQPLPQSIQQ
Sbjct: 505  RLTAIMEKHSMSNKHGWTWSVPKFMKRMKVPDYKDKAVFGVPLIVHVQRTGQPLPQSIQQ 564

Query: 1098 AMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADMLKQYFRDL 1157
            A+RYLR++CLDQVGLFRKSGVKSRI ALRQMNE   + VNYE QSAYDVADM+KQ+FRDL
Sbjct: 565  ALRYLRSNCLDQVGLFRKSGVKSRIHALRQMNENFPENVNYEDQSAYDVADMVKQFFRDL 624

Query: 1158 PEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKE 1217
            PEPL TNKLSETFL IYQYV K+QRLQA++AAI+LL DENREVLQTLL FL+DV   V+E
Sbjct: 625  PEPLFTNKLSETFLHIYQYVSKEQRLQAVQAAILLLADENREVLQTLLCFLNDVVNLVEE 684

Query: 1218 NQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMI 1277
            NQMTP NLAVCLAPSLFHLN LK+E SSPRV+Q+K + GKPDQKDLNENLAA QGLAHMI
Sbjct: 685  NQMTPMNLAVCLAPSLFHLNLLKKE-SSPRVIQKKYATGKPDQKDLNENLAAAQGLAHMI 743

Query: 1278 AECKKLFQVPEEM-SRCRNSYTEQELKPLTLEALGHLGNDDSADYQHFLQDCVDGLFKEV 1336
             EC +LF+VP E+ ++ RNSY E E+   TLE LG    +  A +  +L   + GL KE 
Sbjct: 744  MECDRLFEVPHELVAQSRNSYVEAEIHVPTLEELGTQLEESGATFHTYLNHLIQGLQKEA 803

Query: 1337 KEKFKGWVSYSTSEQAELSYKKVSEGPPLRLWRSVIEVPAVPEEILKRLLKEQHLWDVDL 1396
            KEKFKGWV+ S+++  +L++KKV +G PL+LW++ +EV A P  +L R+L+E+HLWD D 
Sbjct: 804  KEKFKGWVTCSSTDNTDLAFKKVGDGNPLKLWKASVEVEAPPSVVLNRVLRERHLWDEDF 863

Query: 1397 LDSKVIEILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPKGACALLLTSVDHDRAPV 1456
            +  KV+E LD QTEIYQYV NSMAPHP+RD+VVLRTW+T+LPKG C L+  SV+H+ A +
Sbjct: 864  VQWKVVETLDRQTEIYQYVLNSMAPHPSRDFVVLRTWKTDLPKGMCTLVSLSVEHEEAQL 923

Query: 1457 V-GVRVNVLLSRYLIEPCGPGKSKLTYMCRVDLRGHMPEWYTKSFGHLCAAEVVKIRDSF 1515
            + GVR  V+ S+YLIEPCG GKS+LT++CR+DL+GH PEWY+K FGHLCAAEV +IR+SF
Sbjct: 924  LGGVRAVVMDSQYLIEPCGSGKSRLTHICRIDLKGHSPEWYSKGFGHLCAAEVARIRNSF 983

Query: 1516 SNQNTETKDTK 1526
                 E  +TK
Sbjct: 984  QPLIAEGPETK 994


>gi|33188435 deleted in liver cancer 1 isoform 3 [Homo sapiens]
          Length = 498

 Score =  898 bits (2321), Expect = 0.0
 Identities = 448/453 (98%), Positives = 452/453 (99%)

Query: 1   MSVAIRKRSWEEHVTHWMGQPFNSDDRNTACHHGLVADSLQASMEKDATLNVDRKEKCVS 60
           MSVAIRKRSWEEHVTHWMGQPFNSDDRNTACHHGLVADSLQASMEKDATLNVDRKEKCVS
Sbjct: 1   MSVAIRKRSWEEHVTHWMGQPFNSDDRNTACHHGLVADSLQASMEKDATLNVDRKEKCVS 60

Query: 61  LPDCCHGSELRDFPGRPMGHLSKDVDENDSHEGEDQFLSLEASTETLVHVSDEDNNADLC 120
           LPDCCHGSELRDFPGRPMGHLSKDVDENDSHEGEDQFLSLEASTETLVHVSDEDNNADLC
Sbjct: 61  LPDCCHGSELRDFPGRPMGHLSKDVDENDSHEGEDQFLSLEASTETLVHVSDEDNNADLC 120

Query: 121 LTDDKQVLNTQGQKTSGQHMIQGAGSLEKALPIIQSNQVSSNSWGIAGETELALVKESGE 180
           LTDDKQVLNTQGQKTSGQHMIQGAGSLEKALPIIQSNQVSSNSWGIAGETELALVKESGE
Sbjct: 121 LTDDKQVLNTQGQKTSGQHMIQGAGSLEKALPIIQSNQVSSNSWGIAGETELALVKESGE 180

Query: 181 RKVTDSISKSLELCNEISLSEIKDAPKVNAVDTLNVKDIAPEKQLLNSAVIAQQRRKPDP 240
           RKVTDSISKSLELCNEISLSEIKDAPKVNAVDTLNVKDIAPEKQLLNSAVIAQQRRKPDP
Sbjct: 181 RKVTDSISKSLELCNEISLSEIKDAPKVNAVDTLNVKDIAPEKQLLNSAVIAQQRRKPDP 240

Query: 241 PKDENERSTCNVVQDEFLDTPCTNRGLPLLKTDFGSCLLQPPSCPNGMSAENGLEKSGFS 300
           PKDENERSTCNVVQ+EFLDTPCTNRGLPLLKTDFGSCLLQPPSCPNGMSAENGLEKSGFS
Sbjct: 241 PKDENERSTCNVVQNEFLDTPCTNRGLPLLKTDFGSCLLQPPSCPNGMSAENGLEKSGFS 300

Query: 301 QHQNKSPPKVKAEDGMQCLQLKETLATQEPTDNQVRLRKRKEIREDRDRARLDSMVLLIM 360
           QHQNKSPPKVKAEDGMQCLQLKETLATQEPTDNQVRLRKRKEIREDRDRARLDSMVLLIM
Sbjct: 301 QHQNKSPPKVKAEDGMQCLQLKETLATQEPTDNQVRLRKRKEIREDRDRARLDSMVLLIM 360

Query: 361 KLDQLDQDIENALSTSSSPSGTPTNLRRHVPDLESGSESGADTISVNQTRVNLSSDTEST 420
           KLDQLDQDIENALSTSSSPSGTPTNLRRHVPDLESGSESGADTISVNQTRVNLSSDTEST
Sbjct: 361 KLDQLDQDIENALSTSSSPSGTPTNLRRHVPDLESGSESGADTISVNQTRVNLSSDTEST 420

Query: 421 DLPSSTPVANSGTKPKTTAIQGISEKEKAEIEA 453
           DLPSSTPVANSGTKPKTTAIQGISEKEKA +++
Sbjct: 421 DLPSSTPVANSGTKPKTTAIQGISEKEKAAVKS 453


>gi|215820652 StAR-related lipid transfer (START) domain containing 8
            isoform b [Homo sapiens]
          Length = 1023

 Score =  653 bits (1684), Expect = 0.0
 Identities = 335/577 (58%), Positives = 430/577 (74%), Gaps = 15/577 (2%)

Query: 962  SDLDSTGNSLNEPEEPSEIP--------ERRDSGVGASLTRSNRHRLRWHSFQSSHRPSL 1013
            S+LDS+GNS+NE E    +         ERRDSGVGASLTR  R +LRWHSFQ+SHRPSL
Sbjct: 449  SELDSSGNSMNEAEAAGPLAGLQASMPRERRDSGVGASLTRPCR-KLRWHSFQNSHRPSL 507

Query: 1014 NSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDR 1073
            NS SL+IN Q   Q+NLL K SLL+LTA +EKYT  +K G+ W++PKFM+R K PDY+ +
Sbjct: 508  NSESLEINRQFAGQINLLHKGSLLRLTAFMEKYTVPHKQGWVWSMPKFMRRNKTPDYRGQ 567

Query: 1074 SVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAI 1133
             VFGVP  ++VQRTGQPLPQSIQQAMRYLR+ CLDQVG+FRKSGVKSRIQ LRQMNE + 
Sbjct: 568  HVFGVPPLIHVQRTGQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNETSP 627

Query: 1134 DCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLL 1193
            D V YEGQSAYDVAD+LKQYFRDLPEP+ T+KL+ TFLQIYQ +PKDQ L A +AA +LL
Sbjct: 628  DNVCYEGQSAYDVADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAAAQAATLLL 687

Query: 1194 PDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQ 1253
            PDENREVLQTLLYFLSD+ A+ +ENQMT  NLAVCLAPS+FHLN  K+++ SPR+  ++ 
Sbjct: 688  PDENREVLQTLLYFLSDI-ASAEENQMTAGNLAVCLAPSIFHLNVSKKDSPSPRIKSKRS 746

Query: 1254 SLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEM-SRCRNSYTEQELKPLTLEALGH 1312
             +G+P  +DL++N+AATQGL+HMI++CKKLFQVP++M  +  +SY+  EL P    AL  
Sbjct: 747  LIGRPGPRDLSDNMAATQGLSHMISDCKKLFQVPQDMVLQLCSSYSAAELSP-PGPALAE 805

Query: 1313 LGNDDSA--DYQHFLQDCVDGLFKEVKEKFKGWVSYSTSEQAELSYKKVSEGPPLRLWRS 1370
            L    +A      ++++ +  L ++  E+FKGW+S    +  EL+ +K  +G PLRLW++
Sbjct: 806  LRQAQAAGVSLSLYMEENIQDLLRDAAERFKGWMSVPGPQHTELACRKAPDGHPLRLWKA 865

Query: 1371 VIEVPAVPEEILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQNSMAPHPARDYVVL 1430
              EV A P  +L R+L+E+ LWD DLL ++V+E L    E+Y YV +SMAPHP RD+VVL
Sbjct: 866  STEVAAPPAVVLHRVLRERALWDEDLLRAQVLEALMPGVELYHYVTDSMAPHPCRDFVVL 925

Query: 1431 RTWRTNLPKGACALLLTSVDHDR-APVVGVRVNVLLSRYLIEPCGPGKSKLTYMCRVDLR 1489
            R WR++LP+G C L+  S+D ++  P  GVR  +L S+YL+EPCG G+S+LT++CR DLR
Sbjct: 926  RMWRSDLPRGGCLLVSQSLDPEQPVPESGVRALMLTSQYLMEPCGLGRSRLTHICRADLR 985

Query: 1490 GHMPEWYTKSFGHLCAAEVVKIRDSFSNQNTETKDTK 1526
            G  P+WY K FGHLCA EV KIRDSF        +TK
Sbjct: 986  GRSPDWYNKVFGHLCAMEVAKIRDSFPTLQAAGPETK 1022



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 60/187 (32%), Positives = 82/187 (43%), Gaps = 43/187 (22%)

Query: 505 TLNKCAVMKLEISPHRKRSDDSDEDEPCAISGKWTFQRDSKRWSRLEEFDVFSPKQDLVP 564
           TLN CA MKLE+    K+++DS+E+E C IS  W FQ++SK WS +   D+ +P      
Sbjct: 2   TLNNCASMKLEVHFQSKQNEDSEEEEQCTISSHWAFQQESKCWSPMGSSDLLAP------ 55

Query: 565 GSPDDSHPKDGPSPGGTLMDLSERQEVSSVRSLSSTGSLP--SHAPPSEDAATPRTNSVI 622
                      PSPG     L       SV +  S  SLP  + + P E A  P      
Sbjct: 56  -----------PSPG-----LPATSSCESVLTELSATSLPVITVSLPPEPADLP------ 93

Query: 623 SVCSSSNLAGNDDSFGSLPSPKELSSFSFSMKGHEKTAKS--KTRSLLKRMESLKLKSSH 680
                  L G   S     S + L S +   +G +  AK   + RS LK +ESL+ K   
Sbjct: 94  -------LPGRAPS----SSDRPLLSPTQGQEGPQDKAKKRHRNRSFLKHLESLRRKEKS 142

Query: 681 HSKHKAP 687
            S+   P
Sbjct: 143 GSQQAEP 149



 Score = 65.9 bits (159), Expect = 3e-10
 Identities = 59/217 (27%), Positives = 85/217 (39%), Gaps = 45/217 (20%)

Query: 742 SSSSQSETSSAVSTPSPVTRTRSLSACNKRVGMYLEGFDPFNQSTFNNVVEQNFKNRESY 801
           S S Q+E   + +T   V++  S  +C    G    GF         +        R+++
Sbjct: 142 SGSQQAEPKHSPATSEKVSKASSFRSCR---GFLSAGFYRAKNWAATSAGGSGANTRKAW 198

Query: 802 PE---------------DTVFYIPEDHKPGTFPKALTNGSFSPSGNNGSVNWRTGSFHGP 846
                            D + ++P DHKPGTFP++L+  S  P   +   +W+ G     
Sbjct: 199 EAWPVASFRHPQWTHRGDCLVHVPGDHKPGTFPRSLSIESLCPEDGHRLADWQPG----- 253

Query: 847 GHISLRRENSSDSPKELKRRNSSSSMSSRLSIYDNVPGSILYSSSGDLADLENED----- 901
                RR           RR S  S  S  S YDN+P   LY +   +   E ED     
Sbjct: 254 -----RRWGCEG------RRGSCGSTGSHASTYDNLPE--LYPAEPVMVGAEAEDEDDEE 300

Query: 902 ---IFPELDDILYHVKGMQRIVNQWSE-KFSDEGDSD 934
               +  LDDIL HV G+Q+ V  WS   + D G  D
Sbjct: 301 SGGSYAHLDDILQHVWGLQQRVELWSRAMYPDLGPGD 337


>gi|215820650 StAR-related lipid transfer (START) domain containing 8
            isoform a [Homo sapiens]
          Length = 1103

 Score =  653 bits (1684), Expect = 0.0
 Identities = 335/577 (58%), Positives = 430/577 (74%), Gaps = 15/577 (2%)

Query: 962  SDLDSTGNSLNEPEEPSEIP--------ERRDSGVGASLTRSNRHRLRWHSFQSSHRPSL 1013
            S+LDS+GNS+NE E    +         ERRDSGVGASLTR  R +LRWHSFQ+SHRPSL
Sbjct: 529  SELDSSGNSMNEAEAAGPLAGLQASMPRERRDSGVGASLTRPCR-KLRWHSFQNSHRPSL 587

Query: 1014 NSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDR 1073
            NS SL+IN Q   Q+NLL K SLL+LTA +EKYT  +K G+ W++PKFM+R K PDY+ +
Sbjct: 588  NSESLEINRQFAGQINLLHKGSLLRLTAFMEKYTVPHKQGWVWSMPKFMRRNKTPDYRGQ 647

Query: 1074 SVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAI 1133
             VFGVP  ++VQRTGQPLPQSIQQAMRYLR+ CLDQVG+FRKSGVKSRIQ LRQMNE + 
Sbjct: 648  HVFGVPPLIHVQRTGQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNETSP 707

Query: 1134 DCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLL 1193
            D V YEGQSAYDVAD+LKQYFRDLPEP+ T+KL+ TFLQIYQ +PKDQ L A +AA +LL
Sbjct: 708  DNVCYEGQSAYDVADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAAAQAATLLL 767

Query: 1194 PDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQ 1253
            PDENREVLQTLLYFLSD+ A+ +ENQMT  NLAVCLAPS+FHLN  K+++ SPR+  ++ 
Sbjct: 768  PDENREVLQTLLYFLSDI-ASAEENQMTAGNLAVCLAPSIFHLNVSKKDSPSPRIKSKRS 826

Query: 1254 SLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEM-SRCRNSYTEQELKPLTLEALGH 1312
             +G+P  +DL++N+AATQGL+HMI++CKKLFQVP++M  +  +SY+  EL P    AL  
Sbjct: 827  LIGRPGPRDLSDNMAATQGLSHMISDCKKLFQVPQDMVLQLCSSYSAAELSP-PGPALAE 885

Query: 1313 LGNDDSA--DYQHFLQDCVDGLFKEVKEKFKGWVSYSTSEQAELSYKKVSEGPPLRLWRS 1370
            L    +A      ++++ +  L ++  E+FKGW+S    +  EL+ +K  +G PLRLW++
Sbjct: 886  LRQAQAAGVSLSLYMEENIQDLLRDAAERFKGWMSVPGPQHTELACRKAPDGHPLRLWKA 945

Query: 1371 VIEVPAVPEEILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQNSMAPHPARDYVVL 1430
              EV A P  +L R+L+E+ LWD DLL ++V+E L    E+Y YV +SMAPHP RD+VVL
Sbjct: 946  STEVAAPPAVVLHRVLRERALWDEDLLRAQVLEALMPGVELYHYVTDSMAPHPCRDFVVL 1005

Query: 1431 RTWRTNLPKGACALLLTSVDHDR-APVVGVRVNVLLSRYLIEPCGPGKSKLTYMCRVDLR 1489
            R WR++LP+G C L+  S+D ++  P  GVR  +L S+YL+EPCG G+S+LT++CR DLR
Sbjct: 1006 RMWRSDLPRGGCLLVSQSLDPEQPVPESGVRALMLTSQYLMEPCGLGRSRLTHICRADLR 1065

Query: 1490 GHMPEWYTKSFGHLCAAEVVKIRDSFSNQNTETKDTK 1526
            G  P+WY K FGHLCA EV KIRDSF        +TK
Sbjct: 1066 GRSPDWYNKVFGHLCAMEVAKIRDSFPTLQAAGPETK 1102



 Score =  149 bits (375), Expect = 3e-35
 Identities = 97/246 (39%), Positives = 128/246 (52%), Gaps = 43/246 (17%)

Query: 446 KEKAEIEAKEACDWLRATGFPQYAQLYEDFLFPIDISLVKREHDFLDRDAIEALCRRLNT 505
           K+ AE EAK AC+WL+ATGFPQY QL+E+  FP+DI  VK+ H FLD D++ ALCRRL T
Sbjct: 23  KKNAEAEAKRACEWLQATGFPQYVQLFEEGSFPLDIGSVKKNHGFLDEDSLGALCRRLMT 82

Query: 506 LNKCAVMKLEISPHRKRSDDSDEDEPCAISGKWTFQRDSKRWSRLEEFDVFSPKQDLVPG 565
           LN CA MKLE+    K+++DS+E+E C IS  W FQ++SK WS +   D+ +P       
Sbjct: 83  LNNCASMKLEVHFQSKQNEDSEEEEQCTISSHWAFQQESKCWSPMGSSDLLAP------- 135

Query: 566 SPDDSHPKDGPSPGGTLMDLSERQEVSSVRSLSSTGSLP--SHAPPSEDAATPRTNSVIS 623
                     PSPG     L       SV +  S  SLP  + + P E A  P       
Sbjct: 136 ----------PSPG-----LPATSSCESVLTELSATSLPVITVSLPPEPADLP------- 173

Query: 624 VCSSSNLAGNDDSFGSLPSPKELSSFSFSMKGHEKTAKS--KTRSLLKRMESLKLKSSHH 681
                 L G   S     S + L S +   +G +  AK   + RS LK +ESL+ K    
Sbjct: 174 ------LPGRAPS----SSDRPLLSPTQGQEGPQDKAKKRHRNRSFLKHLESLRRKEKSG 223

Query: 682 SKHKAP 687
           S+   P
Sbjct: 224 SQQAEP 229



 Score = 65.9 bits (159), Expect = 3e-10
 Identities = 59/217 (27%), Positives = 85/217 (39%), Gaps = 45/217 (20%)

Query: 742 SSSSQSETSSAVSTPSPVTRTRSLSACNKRVGMYLEGFDPFNQSTFNNVVEQNFKNRESY 801
           S S Q+E   + +T   V++  S  +C    G    GF         +        R+++
Sbjct: 222 SGSQQAEPKHSPATSEKVSKASSFRSCR---GFLSAGFYRAKNWAATSAGGSGANTRKAW 278

Query: 802 PE---------------DTVFYIPEDHKPGTFPKALTNGSFSPSGNNGSVNWRTGSFHGP 846
                            D + ++P DHKPGTFP++L+  S  P   +   +W+ G     
Sbjct: 279 EAWPVASFRHPQWTHRGDCLVHVPGDHKPGTFPRSLSIESLCPEDGHRLADWQPG----- 333

Query: 847 GHISLRRENSSDSPKELKRRNSSSSMSSRLSIYDNVPGSILYSSSGDLADLENED----- 901
                RR           RR S  S  S  S YDN+P   LY +   +   E ED     
Sbjct: 334 -----RRWGCEG------RRGSCGSTGSHASTYDNLPE--LYPAEPVMVGAEAEDEDDEE 380

Query: 902 ---IFPELDDILYHVKGMQRIVNQWSE-KFSDEGDSD 934
               +  LDDIL HV G+Q+ V  WS   + D G  D
Sbjct: 381 SGGSYAHLDDILQHVWGLQQRVELWSRAMYPDLGPGD 417


>gi|31543659 StAR-related lipid transfer (START) domain containing 8
            isoform b [Homo sapiens]
          Length = 1023

 Score =  653 bits (1684), Expect = 0.0
 Identities = 335/577 (58%), Positives = 430/577 (74%), Gaps = 15/577 (2%)

Query: 962  SDLDSTGNSLNEPEEPSEIP--------ERRDSGVGASLTRSNRHRLRWHSFQSSHRPSL 1013
            S+LDS+GNS+NE E    +         ERRDSGVGASLTR  R +LRWHSFQ+SHRPSL
Sbjct: 449  SELDSSGNSMNEAEAAGPLAGLQASMPRERRDSGVGASLTRPCR-KLRWHSFQNSHRPSL 507

Query: 1014 NSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDR 1073
            NS SL+IN Q   Q+NLL K SLL+LTA +EKYT  +K G+ W++PKFM+R K PDY+ +
Sbjct: 508  NSESLEINRQFAGQINLLHKGSLLRLTAFMEKYTVPHKQGWVWSMPKFMRRNKTPDYRGQ 567

Query: 1074 SVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAI 1133
             VFGVP  ++VQRTGQPLPQSIQQAMRYLR+ CLDQVG+FRKSGVKSRIQ LRQMNE + 
Sbjct: 568  HVFGVPPLIHVQRTGQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNETSP 627

Query: 1134 DCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLL 1193
            D V YEGQSAYDVAD+LKQYFRDLPEP+ T+KL+ TFLQIYQ +PKDQ L A +AA +LL
Sbjct: 628  DNVCYEGQSAYDVADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAAAQAATLLL 687

Query: 1194 PDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQ 1253
            PDENREVLQTLLYFLSD+ A+ +ENQMT  NLAVCLAPS+FHLN  K+++ SPR+  ++ 
Sbjct: 688  PDENREVLQTLLYFLSDI-ASAEENQMTAGNLAVCLAPSIFHLNVSKKDSPSPRIKSKRS 746

Query: 1254 SLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEM-SRCRNSYTEQELKPLTLEALGH 1312
             +G+P  +DL++N+AATQGL+HMI++CKKLFQVP++M  +  +SY+  EL P    AL  
Sbjct: 747  LIGRPGPRDLSDNMAATQGLSHMISDCKKLFQVPQDMVLQLCSSYSAAELSP-PGPALAE 805

Query: 1313 LGNDDSA--DYQHFLQDCVDGLFKEVKEKFKGWVSYSTSEQAELSYKKVSEGPPLRLWRS 1370
            L    +A      ++++ +  L ++  E+FKGW+S    +  EL+ +K  +G PLRLW++
Sbjct: 806  LRQAQAAGVSLSLYMEENIQDLLRDAAERFKGWMSVPGPQHTELACRKAPDGHPLRLWKA 865

Query: 1371 VIEVPAVPEEILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQNSMAPHPARDYVVL 1430
              EV A P  +L R+L+E+ LWD DLL ++V+E L    E+Y YV +SMAPHP RD+VVL
Sbjct: 866  STEVAAPPAVVLHRVLRERALWDEDLLRAQVLEALMPGVELYHYVTDSMAPHPCRDFVVL 925

Query: 1431 RTWRTNLPKGACALLLTSVDHDR-APVVGVRVNVLLSRYLIEPCGPGKSKLTYMCRVDLR 1489
            R WR++LP+G C L+  S+D ++  P  GVR  +L S+YL+EPCG G+S+LT++CR DLR
Sbjct: 926  RMWRSDLPRGGCLLVSQSLDPEQPVPESGVRALMLTSQYLMEPCGLGRSRLTHICRADLR 985

Query: 1490 GHMPEWYTKSFGHLCAAEVVKIRDSFSNQNTETKDTK 1526
            G  P+WY K FGHLCA EV KIRDSF        +TK
Sbjct: 986  GRSPDWYNKVFGHLCAMEVAKIRDSFPTLQAAGPETK 1022



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 60/187 (32%), Positives = 82/187 (43%), Gaps = 43/187 (22%)

Query: 505 TLNKCAVMKLEISPHRKRSDDSDEDEPCAISGKWTFQRDSKRWSRLEEFDVFSPKQDLVP 564
           TLN CA MKLE+    K+++DS+E+E C IS  W FQ++SK WS +   D+ +P      
Sbjct: 2   TLNNCASMKLEVHFQSKQNEDSEEEEQCTISSHWAFQQESKCWSPMGSSDLLAP------ 55

Query: 565 GSPDDSHPKDGPSPGGTLMDLSERQEVSSVRSLSSTGSLP--SHAPPSEDAATPRTNSVI 622
                      PSPG     L       SV +  S  SLP  + + P E A  P      
Sbjct: 56  -----------PSPG-----LPATSSCESVLTELSATSLPVITVSLPPEPADLP------ 93

Query: 623 SVCSSSNLAGNDDSFGSLPSPKELSSFSFSMKGHEKTAKS--KTRSLLKRMESLKLKSSH 680
                  L G   S     S + L S +   +G +  AK   + RS LK +ESL+ K   
Sbjct: 94  -------LPGRAPS----SSDRPLLSPTQGQEGPQDKAKKRHRNRSFLKHLESLRRKEKS 142

Query: 681 HSKHKAP 687
            S+   P
Sbjct: 143 GSQQAEP 149



 Score = 65.9 bits (159), Expect = 3e-10
 Identities = 59/217 (27%), Positives = 85/217 (39%), Gaps = 45/217 (20%)

Query: 742 SSSSQSETSSAVSTPSPVTRTRSLSACNKRVGMYLEGFDPFNQSTFNNVVEQNFKNRESY 801
           S S Q+E   + +T   V++  S  +C    G    GF         +        R+++
Sbjct: 142 SGSQQAEPKHSPATSEKVSKASSFRSCR---GFLSAGFYRAKNWAATSAGGSGANTRKAW 198

Query: 802 PE---------------DTVFYIPEDHKPGTFPKALTNGSFSPSGNNGSVNWRTGSFHGP 846
                            D + ++P DHKPGTFP++L+  S  P   +   +W+ G     
Sbjct: 199 EAWPVASFRHPQWTHRGDCLVHVPGDHKPGTFPRSLSIESLCPEDGHRLADWQPG----- 253

Query: 847 GHISLRRENSSDSPKELKRRNSSSSMSSRLSIYDNVPGSILYSSSGDLADLENED----- 901
                RR           RR S  S  S  S YDN+P   LY +   +   E ED     
Sbjct: 254 -----RRWGCEG------RRGSCGSTGSHASTYDNLPE--LYPAEPVMVGAEAEDEDDEE 300

Query: 902 ---IFPELDDILYHVKGMQRIVNQWSE-KFSDEGDSD 934
               +  LDDIL HV G+Q+ V  WS   + D G  D
Sbjct: 301 SGGSYAHLDDILQHVWGLQQRVELWSRAMYPDLGPGD 337


>gi|39932589 Rho GTPase activating protein 18 [Homo sapiens]
          Length = 663

 Score = 99.4 bits (246), Expect = 2e-20
 Identities = 64/195 (32%), Positives = 103/195 (52%), Gaps = 8/195 (4%)

Query: 1060 KFMKRIKVPDYKDRSVFGVPLTVNVQRT-----GQPLPQSIQQAMRYLRNHCLDQVGLFR 1114
            K  K +K+   KD  +F VPLT  +++      G  +P   Q+ +  +    L+  GL R
Sbjct: 307  KQQKAVKIKT-KDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGLLR 365

Query: 1115 KSGVKSRIQALRQMNEGAI--DCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQ 1172
              G   RI+ L Q  E        N+E    +D A +LK + R+LP+PL++ +  + F  
Sbjct: 366  IPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQA 425

Query: 1173 IYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPS 1232
            +     K Q+LQA+   ++LLPD NR+ L+ LL FL  V    ++N+MT  N+A+ +AP+
Sbjct: 426  VQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMAPN 485

Query: 1233 LFHLNTLKRENSSPR 1247
            LF  + L  ++S  R
Sbjct: 486  LFMCHALGLKSSEQR 500


>gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens]
          Length = 771

 Score = 91.7 bits (226), Expect = 5e-18
 Identities = 65/211 (30%), Positives = 100/211 (47%), Gaps = 23/211 (10%)

Query: 1091 LPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADML 1150
            +P+ +    ++L  H L  VG+FR    K R++ LR+  +  ID    E  S +DVA +L
Sbjct: 207  VPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALL 266

Query: 1151 KQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSD 1210
            K++ RD+P+PL+T +L   F+      P++Q L  ++  I LLP  N + L  LL FLS 
Sbjct: 267  KEFLRDMPDPLLTRELYTAFINTLLLEPEEQ-LGTLQLLIYLLPPCNCDTLHRLLQFLSI 325

Query: 1211 VT-----------AAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPD 1259
            V              V  N+MT  NLA    P+L H     ++ SS +    + S     
Sbjct: 326  VARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLH-----KQKSSDKEFSVQSS----- 375

Query: 1260 QKDLNENLAATQGLAHMIAECKKLFQVPEEM 1290
                 E+ A    +  MI   + LF VP ++
Sbjct: 376  -ARAEESTAIIAVVQKMIENYEALFMVPPDL 405


>gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo sapiens]
          Length = 765

 Score = 91.7 bits (226), Expect = 5e-18
 Identities = 65/211 (30%), Positives = 100/211 (47%), Gaps = 23/211 (10%)

Query: 1091 LPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADML 1150
            +P+ +    ++L  H L  VG+FR    K R++ LR+  +  ID    E  S +DVA +L
Sbjct: 410  VPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALL 469

Query: 1151 KQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSD 1210
            K++ RD+P+PL+T +L   F+      P++Q L  ++  I LLP  N + L  LL FLS 
Sbjct: 470  KEFLRDMPDPLLTRELYTAFINTLLLEPEEQ-LGTLQLLIYLLPPCNCDTLHRLLQFLSI 528

Query: 1211 VT-----------AAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPD 1259
            V              V  N+MT  NLA    P+L H     ++ SS +    + S     
Sbjct: 529  VARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLH-----KQKSSDKEFSVQSS----- 578

Query: 1260 QKDLNENLAATQGLAHMIAECKKLFQVPEEM 1290
                 E+ A    +  MI   + LF VP ++
Sbjct: 579  -ARAEESTAIIAVVQKMIENYEALFMVPPDL 608


>gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo sapiens]
          Length = 974

 Score = 91.7 bits (226), Expect = 5e-18
 Identities = 65/211 (30%), Positives = 100/211 (47%), Gaps = 23/211 (10%)

Query: 1091 LPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADML 1150
            +P+ +    ++L  H L  VG+FR    K R++ LR+  +  ID    E  S +DVA +L
Sbjct: 410  VPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALL 469

Query: 1151 KQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSD 1210
            K++ RD+P+PL+T +L   F+      P++Q L  ++  I LLP  N + L  LL FLS 
Sbjct: 470  KEFLRDMPDPLLTRELYTAFINTLLLEPEEQ-LGTLQLLIYLLPPCNCDTLHRLLQFLSI 528

Query: 1211 VT-----------AAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPD 1259
            V              V  N+MT  NLA    P+L H     ++ SS +    + S     
Sbjct: 529  VARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLH-----KQKSSDKEFSVQSS----- 578

Query: 1260 QKDLNENLAATQGLAHMIAECKKLFQVPEEM 1290
                 E+ A    +  MI   + LF VP ++
Sbjct: 579  -ARAEESTAIIAVVQKMIENYEALFMVPPDL 608


>gi|239757488 PREDICTED: chromosome 20 open reading frame 95 [Homo
            sapiens]
          Length = 622

 Score = 88.2 bits (217), Expect = 6e-17
 Identities = 64/220 (29%), Positives = 106/220 (48%), Gaps = 21/220 (9%)

Query: 1024 SVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYK--DRSVFGVPLT 1081
            S+  M  +   +L++LTAL +             +   +KR K   +K  +  +FGVPL 
Sbjct: 226  SLQDMRKVPSLALIELTALCD------------ILGLDLKRSKAGKWKAAETRLFGVPLD 273

Query: 1082 VNVQRTGQPLPQS-----IQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCV 1136
              ++   + LP +     +Q  +  L    LD  G+ R  G ++R++ L Q  E      
Sbjct: 274  SLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGILRVPGSQARVKGLEQKLERDFYAG 333

Query: 1137 NYEGQSAY--DVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLP 1194
             +     +  D +D+LK++ R LP PL+T +    F  +       QRLQ +   I++LP
Sbjct: 334  LFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAFAVVPNIPNLKQRLQVLHLLILILP 393

Query: 1195 DENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLF 1234
            + NR  L+ LL FL  V A  + N+MT  N++  +AP+LF
Sbjct: 394  EPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMAPNLF 433


>gi|239752003 PREDICTED: chromosome 20 open reading frame 95 [Homo
            sapiens]
          Length = 622

 Score = 88.2 bits (217), Expect = 6e-17
 Identities = 64/220 (29%), Positives = 106/220 (48%), Gaps = 21/220 (9%)

Query: 1024 SVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYK--DRSVFGVPLT 1081
            S+  M  +   +L++LTAL +             +   +KR K   +K  +  +FGVPL 
Sbjct: 226  SLQDMRKVPSLALIELTALCD------------ILGLDLKRSKAGKWKAAETRLFGVPLD 273

Query: 1082 VNVQRTGQPLPQS-----IQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCV 1136
              ++   + LP +     +Q  +  L    LD  G+ R  G ++R++ L Q  E      
Sbjct: 274  SLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGILRVPGSQARVKGLEQKLERDFYAG 333

Query: 1137 NYEGQSAY--DVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLP 1194
             +     +  D +D+LK++ R LP PL+T +    F  +       QRLQ +   I++LP
Sbjct: 334  LFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAFAVVPNIPNLKQRLQVLHLLILILP 393

Query: 1195 DENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLF 1234
            + NR  L+ LL FL  V A  + N+MT  N++  +AP+LF
Sbjct: 394  EPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMAPNLF 433


>gi|239746488 PREDICTED: Rho GTPase-activating protein 18-like [Homo
            sapiens]
          Length = 622

 Score = 88.2 bits (217), Expect = 6e-17
 Identities = 64/220 (29%), Positives = 106/220 (48%), Gaps = 21/220 (9%)

Query: 1024 SVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYK--DRSVFGVPLT 1081
            S+  M  +   +L++LTAL +             +   +KR K   +K  +  +FGVPL 
Sbjct: 226  SLQDMRKVPSLALIELTALCD------------ILGLDLKRSKAGKWKAAETRLFGVPLD 273

Query: 1082 VNVQRTGQPLPQS-----IQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCV 1136
              ++   + LP +     +Q  +  L    LD  G+ R  G ++R++ L Q  E      
Sbjct: 274  SLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGILRVPGSQARVKGLEQKLERDFYAG 333

Query: 1137 NYEGQSAY--DVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLP 1194
             +     +  D +D+LK++ R LP PL+T +    F  +       QRLQ +   I++LP
Sbjct: 334  LFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAFAVVPNIPNLKQRLQVLHLLILILP 393

Query: 1195 DENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLF 1234
            + NR  L+ LL FL  V A  + N+MT  N++  +AP+LF
Sbjct: 394  EPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMAPNLF 433


>gi|54860079 nadrin isoform 1 [Homo sapiens]
          Length = 881

 Score = 88.2 bits (217), Expect = 6e-17
 Identities = 61/201 (30%), Positives = 97/201 (48%), Gaps = 23/201 (11%)

Query: 1038 KLTALLEKYTPSNK-HGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTGQPLPQSIQ 1096
            K  A+LEK  P  + H   WA              ++  FG PL  +++R+G+ +   I+
Sbjct: 225  KALAVLEKTLPEMRAHQDKWA--------------EKPAFGTPLEEHLKRSGREIALPIE 270

Query: 1097 QAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYD----VADMLKQ 1152
              +  L    + + GLFR     S+++ L+     A+DC        Y     VA  LK 
Sbjct: 271  ACVMLLLETGMKEEGLFRIGAGASKLKKLK----AALDCSTSHLDEFYSDPHAVAGALKS 326

Query: 1153 YFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVT 1212
            Y R+LPEPLMT  L E + Q+     +D++LQ +      LP +N    + L+ FL+ + 
Sbjct: 327  YLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKLPPQNFVNFRYLIKFLAKLA 386

Query: 1213 AAVKENQMTPTNLAVCLAPSL 1233
                 N+MTP+N+A+ L P+L
Sbjct: 387  QTSDVNKMTPSNIAIVLGPNL 407


>gi|54860105 nadrin isoform 2 [Homo sapiens]
          Length = 803

 Score = 88.2 bits (217), Expect = 6e-17
 Identities = 61/201 (30%), Positives = 97/201 (48%), Gaps = 23/201 (11%)

Query: 1038 KLTALLEKYTPSNK-HGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTGQPLPQSIQ 1096
            K  A+LEK  P  + H   WA              ++  FG PL  +++R+G+ +   I+
Sbjct: 225  KALAVLEKTLPEMRAHQDKWA--------------EKPAFGTPLEEHLKRSGREIALPIE 270

Query: 1097 QAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYD----VADMLKQ 1152
              +  L    + + GLFR     S+++ L+     A+DC        Y     VA  LK 
Sbjct: 271  ACVMLLLETGMKEEGLFRIGAGASKLKKLK----AALDCSTSHLDEFYSDPHAVAGALKS 326

Query: 1153 YFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVT 1212
            Y R+LPEPLMT  L E + Q+     +D++LQ +      LP +N    + L+ FL+ + 
Sbjct: 327  YLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKLPPQNFVNFRYLIKFLAKLA 386

Query: 1213 AAVKENQMTPTNLAVCLAPSL 1233
                 N+MTP+N+A+ L P+L
Sbjct: 387  QTSDVNKMTPSNIAIVLGPNL 407


>gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]
          Length = 818

 Score = 84.7 bits (208), Expect = 6e-16
 Identities = 54/166 (32%), Positives = 94/166 (56%), Gaps = 8/166 (4%)

Query: 1072 DRSVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEG 1131
            ++  FG PL  ++  +G+ +   I+  +  L    + + GLFR +   S+++ L+     
Sbjct: 249  EKPSFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLK----A 304

Query: 1132 AIDC--VNYEGQSA--YDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIK 1187
            A+DC  V+ +  SA  + +A  LK Y R+LPEPLMT +L + ++Q      +D++LQA+ 
Sbjct: 305  ALDCCVVDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALW 364

Query: 1188 AAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSL 1233
             A   LP  N   ++ L+ FLS ++     N+MTP+N+A+ L P+L
Sbjct: 365  NACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNL 410


>gi|59710113 Rho GTPase activating protein 28 isoform a [Homo sapiens]
          Length = 570

 Score = 83.6 bits (205), Expect = 1e-15
 Identities = 61/219 (27%), Positives = 106/219 (48%), Gaps = 18/219 (8%)

Query: 1024 SVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVN 1083
            S   M  ++  SL++LTA  + +    K           K  KV   +D  +FGVPLTV 
Sbjct: 177  SAEDMKKIRHLSLIELTAFFDAFGIQLKRN---------KTEKVKG-RDNGIFGVPLTVL 226

Query: 1084 V-----QRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAI--DCV 1136
            +     +  G  +P  +Q+    +    L+  G+FR SG  ++++  R+  +     D  
Sbjct: 227  LDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKF 286

Query: 1137 NYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQ-RLQAIKAAIMLLPD 1195
             ++     + A MLK +FR+LP  L   +    F+ + +  P  + + QA+   +M LPD
Sbjct: 287  KWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPD 346

Query: 1196 ENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLF 1234
             NR+  Q L+ F + V A   +N+M+  N++  +AP+LF
Sbjct: 347  ANRDAAQALMTFFNKVIANESKNRMSLWNISTVMAPNLF 385



 Score = 41.2 bits (95), Expect = 0.008
 Identities = 40/156 (25%), Positives = 65/156 (41%), Gaps = 20/156 (12%)

Query: 570 SHPKDGPSPGGTLMDLSERQEVS-------SVRSLSSTGSLPSHAPPSEDAATPRTNSVI 622
           S P D      TL D S+ +E S       SV  L +   LP H+  S +   P  N++ 
Sbjct: 52  SMPDDASLNSTTLSDASQDKEGSFAVPRSDSVAILETIPVLPVHSNGSPEPGQPVQNAI- 110

Query: 623 SVCSSSNLAGNDDSFGSLPSPKELSSFSFSMKGHEKTAKSKTRSLLKRMESLKLKSSHHS 682
                     +DD F     P E    SF +   E   ++  R+ LK+ E  K       
Sbjct: 111 ----------SDDDFLEKNIPPEAEELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTK 160

Query: 683 KHKAPSKLGLIISGPILQEGMDEEKLKQLNCVEISA 718
            +   ++ GL  +G +  E  D +K++ L+ +E++A
Sbjct: 161 FNVQKTRFGLTEAGDLSAE--DMKKIRHLSLIELTA 194


>gi|59710111 Rho GTPase activating protein 28 isoform b [Homo sapiens]
          Length = 563

 Score = 83.6 bits (205), Expect = 1e-15
 Identities = 61/219 (27%), Positives = 106/219 (48%), Gaps = 18/219 (8%)

Query: 1024 SVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVN 1083
            S   M  ++  SL++LTA  + +    K           K  KV   +D  +FGVPLTV 
Sbjct: 177  SAEDMKKIRHLSLIELTAFFDAFGIQLKRN---------KTEKVKG-RDNGIFGVPLTVL 226

Query: 1084 V-----QRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAI--DCV 1136
            +     +  G  +P  +Q+    +    L+  G+FR SG  ++++  R+  +     D  
Sbjct: 227  LDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKF 286

Query: 1137 NYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQ-RLQAIKAAIMLLPD 1195
             ++     + A MLK +FR+LP  L   +    F+ + +  P  + + QA+   +M LPD
Sbjct: 287  KWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPD 346

Query: 1196 ENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLF 1234
             NR+  Q L+ F + V A   +N+M+  N++  +AP+LF
Sbjct: 347  ANRDAAQALMTFFNKVIANESKNRMSLWNISTVMAPNLF 385



 Score = 41.2 bits (95), Expect = 0.008
 Identities = 40/156 (25%), Positives = 65/156 (41%), Gaps = 20/156 (12%)

Query: 570 SHPKDGPSPGGTLMDLSERQEVS-------SVRSLSSTGSLPSHAPPSEDAATPRTNSVI 622
           S P D      TL D S+ +E S       SV  L +   LP H+  S +   P  N++ 
Sbjct: 52  SMPDDASLNSTTLSDASQDKEGSFAVPRSDSVAILETIPVLPVHSNGSPEPGQPVQNAI- 110

Query: 623 SVCSSSNLAGNDDSFGSLPSPKELSSFSFSMKGHEKTAKSKTRSLLKRMESLKLKSSHHS 682
                     +DD F     P E    SF +   E   ++  R+ LK+ E  K       
Sbjct: 111 ----------SDDDFLEKNIPPEAEELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTK 160

Query: 683 KHKAPSKLGLIISGPILQEGMDEEKLKQLNCVEISA 718
            +   ++ GL  +G +  E  D +K++ L+ +E++A
Sbjct: 161 FNVQKTRFGLTEAGDLSAE--DMKKIRHLSLIELTA 194


>gi|40255080 hypothetical protein LOC158763 [Homo sapiens]
          Length = 547

 Score = 83.2 bits (204), Expect = 2e-15
 Identities = 61/229 (26%), Positives = 108/229 (47%), Gaps = 24/229 (10%)

Query: 1075 VFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAID 1134
            + G    +++    + +PQ ++   +++  H L  VG+F       R++ LR+  +  +D
Sbjct: 219  LLGSKRKMSLNPIAKQIPQVVEACCQFIEKHGLSAVGIFTLEYSVQRVRQLREEFDQGLD 278

Query: 1135 CVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLP 1194
             V  + Q+ +DVA +LK++FRD+ + L+ + L  +FL      P+DQ L A++  + L+P
Sbjct: 279  VVLDDNQNVHDVAALLKEFFRDMKDSLLPDDLYMSFLLTATLKPQDQ-LSALQLLVYLMP 337

Query: 1195 DENREVLQTLLYFLSDVT-----------AAVKENQMTPTNLAVCLAPSLFHLNTLKREN 1243
              + + L+ LL  L  +T             V  N+MT TNLA+    +L       +  
Sbjct: 338  PCHSDTLERLLKALHKITENCEDSIGIDGQLVPGNRMTSTNLALVFGSALLKKGKFGKRE 397

Query: 1244 SSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEMSR 1292
            S      RK  LG      ++  +A+   +  MI     LFQVP  + R
Sbjct: 398  S------RKTKLG------IDHYVASVNVVRAMIDNWDVLFQVPPHIQR 434


>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
          Length = 701

 Score = 83.2 bits (204), Expect = 2e-15
 Identities = 50/159 (31%), Positives = 83/159 (52%)

Query: 1075 VFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAID 1134
            V+GV L  ++Q  G+ +   I+  +  L +  + + GLFR +   S ++ L+Q       
Sbjct: 273  VYGVSLATHLQELGREIALPIEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMASDPH 332

Query: 1135 CVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLP 1194
             +       + VA  LK Y R+LPEPLMT  L + +++         RLQA++     LP
Sbjct: 333  SLEEFCSDPHAVAGALKSYLRELPEPLMTFDLYDDWMRAASLKEPGARLQALQEVCSRLP 392

Query: 1195 DENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSL 1233
             EN   L+ L+ FL+ +    + N+MTP+N+A+ L P+L
Sbjct: 393  PENLSNLRYLMKFLARLAEEQEVNKMTPSNIAIVLGPNL 431


>gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens]
          Length = 1444

 Score = 82.8 bits (203), Expect = 2e-15
 Identities = 52/164 (31%), Positives = 85/164 (51%), Gaps = 6/164 (3%)

Query: 1074 SVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAI 1133
            S FG  LT  ++ +GQ +P  ++    ++  H +   G++R SGV S IQ LRQ   G+ 
Sbjct: 17   SAFGCDLTEYLESSGQDVPYVLKSCAEFIETHGIVD-GIYRLSGVTSNIQRLRQ-EFGSD 74

Query: 1134 DCVNYEG----QSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAA 1189
             C +       Q  + V  + K YFR+LP PL+T +L E F +   + P++ +L  I+  
Sbjct: 75   QCPDLTREVYLQDIHCVGSLCKLYFRELPNPLLTYELYEKFTEAVSHCPEEGQLARIQNV 134

Query: 1190 IMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSL 1233
            I  LP  +   L+ L+  L+ + +   +  M   NLA+  AP+L
Sbjct: 135  IQELPPSHYRTLEYLIRHLAHIASFSSKTNMHARNLALVWAPNL 178



 Score = 31.2 bits (69), Expect = 8.0
 Identities = 19/91 (20%), Positives = 43/91 (47%), Gaps = 4/91 (4%)

Query: 369 IENALSTSSSPSGTPTNLRRHVPDLESGSESGADTISVNQTRVNLSSDTESTDLPSSTPV 428
           +   +ST+S+P  TP    + +  LE  S  G+++    +    L ++T +  +P    +
Sbjct: 498 VSAVISTNSTPCRTPPKELQSLSSLEEFSFHGSESGGWPEEEKPLGAETSAASVPKKAGL 557

Query: 429 ANSGTKPKTTAI----QGISEKEKAEIEAKE 455
            ++   P+        +G+S++  A +E K+
Sbjct: 558 EDAKAVPEAPGTVECSKGLSQEPGAHLEEKK 588


>gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo
            sapiens]
          Length = 1499

 Score = 82.0 bits (201), Expect = 4e-15
 Identities = 49/163 (30%), Positives = 90/163 (55%), Gaps = 2/163 (1%)

Query: 1072 DRSVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQAL-RQMNE 1130
            + + FGVPLT  V    +P+P  I++ + Y+    L   G++R SG KS +++L RQ ++
Sbjct: 1243 ESNYFGVPLTT-VVTPEKPIPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQ 1301

Query: 1131 GAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAI 1190
                 +  +  +   VA  +K +F +LP+PL+   +    ++ ++   ++Q+L A+K  +
Sbjct: 1302 DHNLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVL 1361

Query: 1191 MLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSL 1233
               P EN EV + ++  L+ V+   K N MT  NL++C  P+L
Sbjct: 1362 KKFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTL 1404


>gi|5803145 ralA binding protein 1 [Homo sapiens]
          Length = 655

 Score = 82.0 bits (201), Expect = 4e-15
 Identities = 51/174 (29%), Positives = 92/174 (52%), Gaps = 7/174 (4%)

Query: 1064 RIKVPDYKDRSVFGVPLTVNVQRT----GQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVK 1119
            +I VP+ K   +FG+PL   V+RT    G  LP   ++ + Y+  + +   G++R SG+K
Sbjct: 180  QIDVPNLKP--IFGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGIK 237

Query: 1120 SRIQALRQMNEGAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPK 1179
            S++  L+   +   +  N E      VA +LKQY RDLPE L+T +L   F +      +
Sbjct: 238  SKVDELKAAYDRE-ESTNLEDYEPNTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTE 296

Query: 1180 DQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSL 1233
             +++Q  +  +  LP+ N  ++  L+  +  V A   E +M   N+++ L+P++
Sbjct: 297  TEKVQEFQRLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTV 350


>gi|194272142 myosin IXB isoform 2 [Homo sapiens]
          Length = 2022

 Score = 82.0 bits (201), Expect = 4e-15
 Identities = 51/156 (32%), Positives = 80/156 (51%), Gaps = 4/156 (2%)

Query: 1091 LPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADML 1150
            +P  +++ + ++  H L   GL+RKSG  +R + LRQ  +     V  E    + +  +L
Sbjct: 1712 VPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDPAAVKLENFPIHAITGVL 1771

Query: 1151 KQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSD 1210
            KQ+ R+LPEPLMT      FL+  +   K ++L AI A +  LP+ N   L+ L++ L  
Sbjct: 1772 KQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHLPEANHNSLERLIFHLVK 1831

Query: 1211 VTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSP 1246
            V      N+M+P  LA+  AP L        +NS P
Sbjct: 1832 VALLEDVNRMSPGALAIIFAPCLLRC----PDNSDP 1863


>gi|33356170 myosin IXB isoform 1 [Homo sapiens]
          Length = 2157

 Score = 82.0 bits (201), Expect = 4e-15
 Identities = 51/156 (32%), Positives = 80/156 (51%), Gaps = 4/156 (2%)

Query: 1091 LPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADML 1150
            +P  +++ + ++  H L   GL+RKSG  +R + LRQ  +     V  E    + +  +L
Sbjct: 1712 VPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDPAAVKLENFPIHAITGVL 1771

Query: 1151 KQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSD 1210
            KQ+ R+LPEPLMT      FL+  +   K ++L AI A +  LP+ N   L+ L++ L  
Sbjct: 1772 KQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHLPEANHNSLERLIFHLVK 1831

Query: 1211 VTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSP 1246
            V      N+M+P  LA+  AP L        +NS P
Sbjct: 1832 VALLEDVNRMSPGALAIIFAPCLLRC----PDNSDP 1863


>gi|156071465 Rho GTPase activating protein 4 [Homo sapiens]
          Length = 946

 Score = 81.6 bits (200), Expect = 5e-15
 Identities = 53/165 (32%), Positives = 84/165 (50%), Gaps = 4/165 (2%)

Query: 1072 DRSVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEG 1131
            ++ +FG  +   +Q +GQP+P  ++  +R++  + L   G+FR SG + R+  +R   E 
Sbjct: 501  NQRLFGGDMEKFIQSSGQPVPLVVESCIRFINLNGLQHEGIFRVSGAQLRVSEIRDAFER 560

Query: 1132 AIDCVNYEGQSAYD---VADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKA 1188
              D +  EG +A+D   VA +LK YFR L  PL    L    L   +     +R++ +  
Sbjct: 561  GEDPL-VEGCTAHDLDSVAGVLKLYFRSLEPPLFPPDLFGELLASSELEATAERVEHVSR 619

Query: 1189 AIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSL 1233
             +  LP     VL+ L  FL+ +     EN M P NLAVC  P+L
Sbjct: 620  LLWRLPAPVLVVLRYLFTFLNHLAQYSDENMMDPYNLAVCFGPTL 664


>gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]
          Length = 846

 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 56/205 (27%), Positives = 101/205 (49%), Gaps = 4/205 (1%)

Query: 1031 LQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTGQP 1090
            L+ + +  + +  +K T  N   F    P  ++ ++   Y    VFG  L    QR    
Sbjct: 610  LRSFKVSSIDSSEQKKTKKNLKKFLTRRPT-LQAVREKGYIKDQVFGSNLANLCQRENGT 668

Query: 1091 LPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQM--NEGAIDCVNYEGQSAYDVAD 1148
            +P+ ++  + ++  H LD  G++R SG  + IQ LR    ++  +D  + + +  + +  
Sbjct: 669  VPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVITG 728

Query: 1149 MLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFL 1208
             LK +FR+LPEPL T      F+   +  P+ QR+ A+K  I  LP  N++ +Q L   L
Sbjct: 729  ALKMFFRELPEPLFTFNHFNDFVNAIKQEPR-QRVAAVKDLIRQLPKPNQDTMQILFRHL 787

Query: 1209 SDVTAAVKENQMTPTNLAVCLAPSL 1233
              V    ++N+MT  ++A+   P+L
Sbjct: 788  RRVIENGEKNRMTYQSIAIVFGPTL 812


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.129    0.372 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 61,012,689
Number of Sequences: 37866
Number of extensions: 2930875
Number of successful extensions: 9995
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 109
Number of HSP's successfully gapped in prelim test: 140
Number of HSP's that attempted gapping in prelim test: 9333
Number of HSP's gapped (non-prelim): 650
length of query: 1528
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1413
effective length of database: 13,892,928
effective search space: 19630707264
effective search space used: 19630707264
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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