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Search of human proteins with 124001558
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|124001558 ubiquitin specific peptidase 54 [Homo sapiens]
(1684 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|124001558 ubiquitin specific peptidase 54 [Homo sapiens] 3454 0.0
gi|148539600 ubiquitin specific protease 53 [Homo sapiens] 521 e-147
gi|60097902 filaggrin [Homo sapiens] 61 1e-08
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 51 1e-05
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 51 1e-05
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 45 8e-04
gi|153251865 hypothetical protein LOC84226 [Homo sapiens] 42 0.004
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 42 0.007
gi|148806908 fibronectin type III domain containing 1 [Homo sapi... 41 0.009
gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo... 41 0.009
gi|62177129 Nedd4 binding protein 3 [Homo sapiens] 41 0.011
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 40 0.015
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 40 0.015
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 40 0.015
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 40 0.015
gi|38570099 glutamine-rich 1 [Homo sapiens] 40 0.015
gi|38570097 glutamine-rich 1 [Homo sapiens] 40 0.015
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 40 0.019
gi|224586851 sorbin and SH3 domain containing 2 isoform 6 [Homo ... 40 0.025
gi|62122917 filaggrin family member 2 [Homo sapiens] 40 0.025
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 40 0.025
gi|38261962 activating transcription factor 7 interacting protei... 39 0.033
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 39 0.033
gi|217035133 hypothetical protein LOC55765 isoform 2 [Homo sapiens] 39 0.033
gi|217035131 hypothetical protein LOC55765 isoform 1 [Homo sapiens] 39 0.033
gi|91208420 bassoon protein [Homo sapiens] 39 0.043
gi|98961135 family with sequence similarity 48, member A isoform... 39 0.043
gi|13129104 coiled-coil domain containing 86 [Homo sapiens] 39 0.043
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 39 0.056
gi|47578107 delangin isoform B [Homo sapiens] 39 0.056
>gi|124001558 ubiquitin specific peptidase 54 [Homo sapiens]
Length = 1684
Score = 3454 bits (8957), Expect = 0.0
Identities = 1684/1684 (100%), Positives = 1684/1684 (100%)
Query: 1 MSWKRNYFSGGRGSVQGMFAPRSSTSIAPSKGLSNEPGQNSCFLNSALQVLWHLDIFRRS 60
MSWKRNYFSGGRGSVQGMFAPRSSTSIAPSKGLSNEPGQNSCFLNSALQVLWHLDIFRRS
Sbjct: 1 MSWKRNYFSGGRGSVQGMFAPRSSTSIAPSKGLSNEPGQNSCFLNSALQVLWHLDIFRRS 60
Query: 61 FRQLTTHKCMGDSCIFCALKGIFNQFQCSSEKVLPSDTLRSALAKTFQDEQRFQLGIMDD 120
FRQLTTHKCMGDSCIFCALKGIFNQFQCSSEKVLPSDTLRSALAKTFQDEQRFQLGIMDD
Sbjct: 61 FRQLTTHKCMGDSCIFCALKGIFNQFQCSSEKVLPSDTLRSALAKTFQDEQRFQLGIMDD 120
Query: 121 AAECFENLLMRIHFHIADETKEDICTAQHCISHQKFAMTLFEQCVCTSCGATSDPLPFIQ 180
AAECFENLLMRIHFHIADETKEDICTAQHCISHQKFAMTLFEQCVCTSCGATSDPLPFIQ
Sbjct: 121 AAECFENLLMRIHFHIADETKEDICTAQHCISHQKFAMTLFEQCVCTSCGATSDPLPFIQ 180
Query: 181 MVHYISTTSLCNQAICMLERREKPSPSMFGELLQNASTMGDLRNCPSNCGERIRIRRVLM 240
MVHYISTTSLCNQAICMLERREKPSPSMFGELLQNASTMGDLRNCPSNCGERIRIRRVLM
Sbjct: 181 MVHYISTTSLCNQAICMLERREKPSPSMFGELLQNASTMGDLRNCPSNCGERIRIRRVLM 240
Query: 241 NAPQIITIGLVWDSDHSDLAEDVIHSLGTCLKLGDLFFRVTDDRAKQSELYLVGMICYYG 300
NAPQIITIGLVWDSDHSDLAEDVIHSLGTCLKLGDLFFRVTDDRAKQSELYLVGMICYYG
Sbjct: 241 NAPQIITIGLVWDSDHSDLAEDVIHSLGTCLKLGDLFFRVTDDRAKQSELYLVGMICYYG 300
Query: 301 KHYSTFFFQTKIRKWMYFDDAHVKEIGPKWKDVVTKCIKGHYQPLLLLYADPQGTPVSTQ 360
KHYSTFFFQTKIRKWMYFDDAHVKEIGPKWKDVVTKCIKGHYQPLLLLYADPQGTPVSTQ
Sbjct: 301 KHYSTFFFQTKIRKWMYFDDAHVKEIGPKWKDVVTKCIKGHYQPLLLLYADPQGTPVSTQ 360
Query: 361 DLPPQAEFQSYSRTCYDSEDSGREPSISSDTRTDSSTESYPYKHSHHESVVSHFSSDSQG 420
DLPPQAEFQSYSRTCYDSEDSGREPSISSDTRTDSSTESYPYKHSHHESVVSHFSSDSQG
Sbjct: 361 DLPPQAEFQSYSRTCYDSEDSGREPSISSDTRTDSSTESYPYKHSHHESVVSHFSSDSQG 420
Query: 421 TVIYNVENDSMSQSSRDTGHLTDSECNQKHTSKKGSLIERKRSSGRVRRKGDEPQASGYH 480
TVIYNVENDSMSQSSRDTGHLTDSECNQKHTSKKGSLIERKRSSGRVRRKGDEPQASGYH
Sbjct: 421 TVIYNVENDSMSQSSRDTGHLTDSECNQKHTSKKGSLIERKRSSGRVRRKGDEPQASGYH 480
Query: 481 SEGETLKEKQAPRNASKPSSSTNRLRDFKETVSNMIHNRPSLASQTNVGSHCRGRGGDQP 540
SEGETLKEKQAPRNASKPSSSTNRLRDFKETVSNMIHNRPSLASQTNVGSHCRGRGGDQP
Sbjct: 481 SEGETLKEKQAPRNASKPSSSTNRLRDFKETVSNMIHNRPSLASQTNVGSHCRGRGGDQP 540
Query: 541 DKKPPRTLPLHSRDWEIESTSSESKSSSSSKYRPTWRPKRESLNIDSIFSKDKRKHCGYT 600
DKKPPRTLPLHSRDWEIESTSSESKSSSSSKYRPTWRPKRESLNIDSIFSKDKRKHCGYT
Sbjct: 541 DKKPPRTLPLHSRDWEIESTSSESKSSSSSKYRPTWRPKRESLNIDSIFSKDKRKHCGYT 600
Query: 601 QLSPFSEDSAKEFIPDEPSKPPSYDIKFGGPSPQYKRWGPARPGSHLLEQHPRLIQRMES 660
QLSPFSEDSAKEFIPDEPSKPPSYDIKFGGPSPQYKRWGPARPGSHLLEQHPRLIQRMES
Sbjct: 601 QLSPFSEDSAKEFIPDEPSKPPSYDIKFGGPSPQYKRWGPARPGSHLLEQHPRLIQRMES 660
Query: 661 GYESSERNSSSPVSLDAALPESSNVYRDPSAKRSAGLVPSWRHIPKSHSSSILEVDSTAS 720
GYESSERNSSSPVSLDAALPESSNVYRDPSAKRSAGLVPSWRHIPKSHSSSILEVDSTAS
Sbjct: 661 GYESSERNSSSPVSLDAALPESSNVYRDPSAKRSAGLVPSWRHIPKSHSSSILEVDSTAS 720
Query: 721 MGGWTKSQPFSGEEISSKSELDELQEEVARRAQEQELRRKREKELEAAKGFNPHPSRFMD 780
MGGWTKSQPFSGEEISSKSELDELQEEVARRAQEQELRRKREKELEAAKGFNPHPSRFMD
Sbjct: 721 MGGWTKSQPFSGEEISSKSELDELQEEVARRAQEQELRRKREKELEAAKGFNPHPSRFMD 780
Query: 781 LDELQNQGRSDGFERSLQEAESVFEESLHLEQKGDCAAALALCNEAISKLRLALHGASCS 840
LDELQNQGRSDGFERSLQEAESVFEESLHLEQKGDCAAALALCNEAISKLRLALHGASCS
Sbjct: 781 LDELQNQGRSDGFERSLQEAESVFEESLHLEQKGDCAAALALCNEAISKLRLALHGASCS 840
Query: 841 THSRALVDKKLQISIRKARSLQDRMQQQQSPQQPSQPSACLPTQAGTLSQPTSEQPIPLQ 900
THSRALVDKKLQISIRKARSLQDRMQQQQSPQQPSQPSACLPTQAGTLSQPTSEQPIPLQ
Sbjct: 841 THSRALVDKKLQISIRKARSLQDRMQQQQSPQQPSQPSACLPTQAGTLSQPTSEQPIPLQ 900
Query: 901 VLLSQEAQLESGMDTEFGASSFFHSPASCHESHSSLSPESSAPQHSSPSRSALKLLTSVE 960
VLLSQEAQLESGMDTEFGASSFFHSPASCHESHSSLSPESSAPQHSSPSRSALKLLTSVE
Sbjct: 901 VLLSQEAQLESGMDTEFGASSFFHSPASCHESHSSLSPESSAPQHSSPSRSALKLLTSVE 960
Query: 961 VDNIEPSAFHRQGLPKAPGWTEKNSHHSWEPLDAPEGKLQGSRCDNSSCSKLPPQEGRGI 1020
VDNIEPSAFHRQGLPKAPGWTEKNSHHSWEPLDAPEGKLQGSRCDNSSCSKLPPQEGRGI
Sbjct: 961 VDNIEPSAFHRQGLPKAPGWTEKNSHHSWEPLDAPEGKLQGSRCDNSSCSKLPPQEGRGI 1020
Query: 1021 AQEQLFQEKKDPANPSPVMPGIATSERGDEHSLGCSPSNSSAQPSLPLYRTCHPIMPVAS 1080
AQEQLFQEKKDPANPSPVMPGIATSERGDEHSLGCSPSNSSAQPSLPLYRTCHPIMPVAS
Sbjct: 1021 AQEQLFQEKKDPANPSPVMPGIATSERGDEHSLGCSPSNSSAQPSLPLYRTCHPIMPVAS 1080
Query: 1081 SFVLHCPDPVQKTNQCLQGQSLKTSLTLKVDRGSEETYRPEFPSTKGLVRSLAEQFQRMQ 1140
SFVLHCPDPVQKTNQCLQGQSLKTSLTLKVDRGSEETYRPEFPSTKGLVRSLAEQFQRMQ
Sbjct: 1081 SFVLHCPDPVQKTNQCLQGQSLKTSLTLKVDRGSEETYRPEFPSTKGLVRSLAEQFQRMQ 1140
Query: 1141 GVSMRDSTGFKDRSLSGSLRKNSSPSDSKPPFSQGQEKGHWPWAKQQSSLEGGDRPLSWE 1200
GVSMRDSTGFKDRSLSGSLRKNSSPSDSKPPFSQGQEKGHWPWAKQQSSLEGGDRPLSWE
Sbjct: 1141 GVSMRDSTGFKDRSLSGSLRKNSSPSDSKPPFSQGQEKGHWPWAKQQSSLEGGDRPLSWE 1200
Query: 1201 ESTEHSSLALNSGLPNGETSSGGQPRLAEPDIYQEKLSQVRDVRSKDLGSSTDLGTSLPL 1260
ESTEHSSLALNSGLPNGETSSGGQPRLAEPDIYQEKLSQVRDVRSKDLGSSTDLGTSLPL
Sbjct: 1201 ESTEHSSLALNSGLPNGETSSGGQPRLAEPDIYQEKLSQVRDVRSKDLGSSTDLGTSLPL 1260
Query: 1261 DSWVNITRFCDSQLKHGAPRPGMKSSPHDSHTCVTYPERNHILLHPHWNQDTEQETSELE 1320
DSWVNITRFCDSQLKHGAPRPGMKSSPHDSHTCVTYPERNHILLHPHWNQDTEQETSELE
Sbjct: 1261 DSWVNITRFCDSQLKHGAPRPGMKSSPHDSHTCVTYPERNHILLHPHWNQDTEQETSELE 1320
Query: 1321 SLYQASLQASQAGCSGWGQQDTAWHPLSQTGSADGMGRRLHSAHDPGLSKTSTAEMEHGL 1380
SLYQASLQASQAGCSGWGQQDTAWHPLSQTGSADGMGRRLHSAHDPGLSKTSTAEMEHGL
Sbjct: 1321 SLYQASLQASQAGCSGWGQQDTAWHPLSQTGSADGMGRRLHSAHDPGLSKTSTAEMEHGL 1380
Query: 1381 HEARTVRTSQATPCRGLSRECGEDEQYSAENLRRISRSLSGTVVSEREEAPVSSHSFDSS 1440
HEARTVRTSQATPCRGLSRECGEDEQYSAENLRRISRSLSGTVVSEREEAPVSSHSFDSS
Sbjct: 1381 HEARTVRTSQATPCRGLSRECGEDEQYSAENLRRISRSLSGTVVSEREEAPVSSHSFDSS 1440
Query: 1441 NVRKPLETGHRCSSSSSLPVIHDPSVFLLGPQLYLPQPQFLSPDVLMPTMAGEPNRLPGT 1500
NVRKPLETGHRCSSSSSLPVIHDPSVFLLGPQLYLPQPQFLSPDVLMPTMAGEPNRLPGT
Sbjct: 1441 NVRKPLETGHRCSSSSSLPVIHDPSVFLLGPQLYLPQPQFLSPDVLMPTMAGEPNRLPGT 1500
Query: 1501 SRSVQQFLAMCDRGETSQGAKYTGRTLNYQSLPHRSRTDNSWAPWSETNQHIGTRFLTTP 1560
SRSVQQFLAMCDRGETSQGAKYTGRTLNYQSLPHRSRTDNSWAPWSETNQHIGTRFLTTP
Sbjct: 1501 SRSVQQFLAMCDRGETSQGAKYTGRTLNYQSLPHRSRTDNSWAPWSETNQHIGTRFLTTP 1560
Query: 1561 GCNPQLTYTATLPERSKGLQVPHTQSWSDLFHSPSHPPIVHPVYPPSSSLHVPLRSAWNS 1620
GCNPQLTYTATLPERSKGLQVPHTQSWSDLFHSPSHPPIVHPVYPPSSSLHVPLRSAWNS
Sbjct: 1561 GCNPQLTYTATLPERSKGLQVPHTQSWSDLFHSPSHPPIVHPVYPPSSSLHVPLRSAWNS 1620
Query: 1621 DPVPGSRTPGPRRVDMPPDDDWRQSSYASHSGHRRTVGEGFLFVLSDAPRREQIRARVLQ 1680
DPVPGSRTPGPRRVDMPPDDDWRQSSYASHSGHRRTVGEGFLFVLSDAPRREQIRARVLQ
Sbjct: 1621 DPVPGSRTPGPRRVDMPPDDDWRQSSYASHSGHRRTVGEGFLFVLSDAPRREQIRARVLQ 1680
Query: 1681 HSQW 1684
HSQW
Sbjct: 1681 HSQW 1684
>gi|148539600 ubiquitin specific protease 53 [Homo sapiens]
Length = 1073
Score = 521 bits (1343), Expect = e-147
Identities = 313/743 (42%), Positives = 414/743 (55%), Gaps = 80/743 (10%)
Query: 1 MSWKRNYFSGGRGSVQGMFAPRSSTSIAPSKGLSNEPGQNSCFLNSALQVLWHLDIFRRS 60
M+W + G G++ ++ P S S+AP+KGL NEPGQNSCFLNSA+QVLW LDIFRRS
Sbjct: 1 MAWVKFLRKPG-GNLGKVYQPGSMLSLAPTKGLLNEPGQNSCFLNSAVQVLWQLDIFRRS 59
Query: 61 FRQLTTHKCMGDSCIFCALKGIFNQFQCSSEKVLPSDTLRSALAKTFQDEQRFQLGIMDD 120
R LT H C GD+CIFCALK IF QFQ S EK LPSD +R ALA++F+DEQRFQLG+MDD
Sbjct: 60 LRVLTGHVCQGDACIFCALKTIFAQFQHSREKALPSDNIRHALAESFKDEQRFQLGLMDD 119
Query: 121 AAECFENLLMRIHFHIADETKEDICTAQHCISHQKFAMTLFEQCVCTSCGATSDPLPFIQ 180
AAECFEN+L RIHFHI D+CT++ CI+HQKFAMTL+EQCVC SCGA+SDPLPF +
Sbjct: 120 AAECFENMLERIHFHIVPSRDADMCTSKSCITHQKFAMTLYEQCVCRSCGASSDPLPFTE 179
Query: 181 MVHYISTTSLCNQAICMLERREKPSPSMFGELLQNASTMGDLRNCPSNCGERIRIRRVLM 240
V YISTT+LCN+ MLER E+ P MF ELLQ A+T D R CPSNCG++I+IRRVLM
Sbjct: 180 FVRYISTTALCNEVERMLERHERFKPEMFAELLQAANTTDDYRKCPSNCGQKIKIRRVLM 239
Query: 241 NAPQIITIGLVWDSDHSDLAEDVIHSLGTCLKLGDLFFRVTDDRAKQSELYLVGMICYYG 300
N P+I+TIGLVWDS+HSDL E V+ +L T L L LF+RVTD+ AK SEL LVGMICY
Sbjct: 240 NCPEIVTIGLVWDSEHSDLTEAVVRNLATHLYLPGLFYRVTDENAKNSELNLVGMICYTS 299
Query: 301 KHYSTFFFQTKIRKWMYFDDAHVKEIGPKWKDVVTKCIKGHYQPLLLLYADPQGTPVSTQ 360
+HY F F TK KW++FDDA+VKEIG +WKDVV+KCI+ H+QPLLL YA+P GT VST+
Sbjct: 300 QHYCAFAFHTKSSKWVFFDDANVKEIGTRWKDVVSKCIRCHFQPLLLFYANPDGTAVSTE 359
Query: 361 DLPPQAEFQSYSRTCYDSEDSGREPSISSDTRTDSSTESYPYKHSHHESVVSHFSSDSQG 420
D Q S+ ++ ++ + SD ++ + + + + SS ++
Sbjct: 360 DALRQVISWSHYKSVAENMGCEKPVIHKSDNLKENGFGDQAKQRENQKFPTDNISSSNRS 419
Query: 421 TVIYNVENDSMSQSSRDTGHLTDS---ECNQKHTSKKGSLIERKRSSGRVRRK------- 470
V S D EC K +K L +++ + +RK
Sbjct: 420 HSHTGVGKGPAKLSHIDQREKIKDISRECALKAIEQKNLLSSQRKDLEKGQRKDLGRHRD 479
Query: 471 -----------GDEPQASG---------YHSEGETLKEK-----QAPRNASKPSSSTNRL 505
G P +G YHS+G+ + Q+ +A SSS +++
Sbjct: 480 LVDEDLSHFQSGSPPAPNGFKQHGNPHLYHSQGKGSYKHDRVVPQSRASAQIISSSKSQI 539
Query: 506 RDFKETVSNMIHNRPSLASQTNVGSHCRGRGGDQPDKKPPRTLPLHSRDWEIESTSSESK 565
E ++ + + T+ R RG S S SK
Sbjct: 540 LAPGEKITGKVKSDNGTGYDTDSSQDSRDRGN---------------------SCDSSSK 578
Query: 566 SSSSSKYRPTWRPKRESLNIDSIFSK-DKRKHC-----GYTQLSPFSEDSAKEFIPDEPS 619
S + W+P RE+LN+DSIFS+ +KR+H + S+D + P E
Sbjct: 579 SRNRG-----WKPMRETLNVDSIFSESEKRQHSPRHKPNISNKPKSSKDPSFSNWPKENP 633
Query: 620 KPPSYDI--------KFGGPSPQYKRWGPARPGSHLLEQHPR----LIQRMESGYESSER 667
K + G S A L+E +QR ESGYESS+
Sbjct: 634 KQKGLMTIYEDEMKQEIGSRSSLESNGKGAEKNKGLVEGKVHGDNWQMQRTESGYESSDH 693
Query: 668 NSSSPVSLDAALPESSNVYRDPS 690
S+ +LD+ + + + D S
Sbjct: 694 ISNGSTNLDSPVIDGNGTVMDIS 716
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 60.8 bits (146), Expect = 1e-08
Identities = 249/1172 (21%), Positives = 389/1172 (33%), Gaps = 209/1172 (17%)
Query: 365 QAEFQSYSRTCYDSEDSGREPSISSDTRTDSSTESYPYKHSHHESVVSHFSS---DSQGT 421
Q+ +S SRT + E S R+ S S +R ++ S H + H + S+G+
Sbjct: 886 QSGSRSASRTTRNEEQS-RDGSRHSGSRH--------HEASSHADISRHSQAGQGQSEGS 936
Query: 422 VIYNVENDSMSQSSRDTGHLTDSECNQKHTSK--KGSLIERKRSSGRVRRKGDEPQASGY 479
+ S+SQ S GH DSE S+ +GS E+ R R R E +A
Sbjct: 937 RTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHG 996
Query: 480 HS----------EGETLKEKQAPRNASKPSSSTNRLRDFK--ETVSNMIHN---RPSLAS 524
HS ET QA + + SS + ++ + H+ R +S
Sbjct: 997 HSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASS 1056
Query: 525 QTNVGSHCRGRGGDQPDKK------PPRTLPLHSRDWEIESTSSESKS---------SSS 569
H G D + +++ H +D + + ES S S
Sbjct: 1057 AVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGS 1116
Query: 570 SKYRPTWRPKRESLNIDSIFSKDKRKHCGYTQLSPFSEDSAKEFIPDEPSKPPSYDIKFG 629
Y+ + + ES + + S +R+ + Q S SA + D P
Sbjct: 1117 FIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGS----- 1171
Query: 630 GPSPQYKRWGPARPGSHLLEQHPRLIQRMESGYESSERN-SSSPVSLDAALPESSNVYRD 688
+R G R GSH H + + R SG+ S + ++S DA+ +S +
Sbjct: 1172 ------RRGG--RQGSH----HEQSVDR--SGHSGSHHSHTTSQGRSDASHGQSGSRSAS 1217
Query: 689 PSAKRSAGLVPSWRHIPKSHSSSILEVDSTASMGGWTKSQPFS--GEEISSKSELDELQE 746
++ RH H + W S S G+E SS S Q
Sbjct: 1218 RQTRKDKQSGDGSRHSGSRHHEA----------ASWADSSRHSQVGQEQSSGSRTSRHQG 1267
Query: 747 EVARRAQEQELRRKREKELEAAKGFNPHPSRFMDLDELQNQGRSDGFERSLQEAESVFEE 806
+ + E + L + N H S ++ ++ R GF
Sbjct: 1268 SSVSQDSDSERHSDDSERLSGSASRNHHGS---SREQSRDGSRHPGF------------- 1311
Query: 807 SLHLEQKGDCAAALALCNEAISKLRLALHGASCSTHSRALVDKKLQISIRKARSLQDRMQ 866
H E + + A S + H S+H +A+ + R + + +
Sbjct: 1312 --HQEDRASHG------HSADSSRQSGTHHTESSSHGQAVSSHE---QARSSPGERHGSR 1360
Query: 867 QQQSPQQPSQPSACLPTQAGTLSQPTSEQPIPLQVLLSQEAQLESGMDTEFGASSFFHSP 926
QQS S+ S QA + + + + + + E E DT+ S H
Sbjct: 1361 HQQSADS-SRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDS-DTQ---SVSAHGQ 1415
Query: 927 ASCHESHSSLSPESSAPQHSSPSRSALKLLTSVEVDNIEPSAFHRQGLPKAPGWTEKNSH 986
A H+ S + + S SRS L ++S E + + H Q P G + S
Sbjct: 1416 AGPHQQSHKESARGQSGESSGRSRSFLYQVSSHE----QSESTHGQTAPSTGG--RQGSR 1469
Query: 987 HSWEPLDAPEGKLQGSRCDNSSCSKLPPQEGRGIAQEQLFQEKKDPANPSPVMPGIATSE 1046
H A + D + P RG Q ++ D + S T +
Sbjct: 1470 HE----QARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQ 1525
Query: 1047 RGDEHSLGCSPSNSSAQPSLPLYRTCHPIMPVASSFVLHCPDPVQKTNQCLQGQSLKTSL 1106
+ S G S S+++ Q N+ G + S
Sbjct: 1526 GRSDASHGQSGPRSASR---------------------------QTRNEEQSGDGSRHS- 1557
Query: 1107 TLKVDRGSEETYRPEFPSTKGLVRSLAEQFQRMQGVSMRDSTGFKDRSLSGSLRKNSSPS 1166
GS R PST+ + Q QG S T + S R + S
Sbjct: 1558 ------GS----RHHEPSTRA---GSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHS 1604
Query: 1167 DSKPPFSQGQEKGHWPWAKQQSSLEGGDRPLSWEE---STEHSS-LALNSGLPNGETSSG 1222
+ S+ + H+ A++QS G P S +E S HS+ + SG + ETSSG
Sbjct: 1605 EDSERRSESASRNHYGSAREQSR-HGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSG 1663
Query: 1223 GQPRLAEPDIYQEKLSQVRDVRSKDLGSSTDLGTSLPLDSWVNITRFCDSQLKHGAPRPG 1282
GQ ++ + + SSTD GT DS V DS + +
Sbjct: 1664 GQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSV----VGDSGNRGSSGSQA 1719
Query: 1283 MKSSPHDSHTCVTYPERNHILLHPHWNQDTEQETSELES----------LYQASLQA--- 1329
S H S T H PH Q + QE++ +S LYQ S
Sbjct: 1720 SDSEGH-SEESDTQSVSAHGQAGPH--QQSHQESTRGQSGERSGRSGSFLYQVSTHEQSE 1776
Query: 1330 ---SQAGCSGWGQQ--------DTAWHPLSQTGS-------ADGMGRRLHSAHDPGLSKT 1371
+ G S G+Q D++ H SQ G G R S ++ + +
Sbjct: 1777 SAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSS 1836
Query: 1372 STAEMEHGLHEARTVRTSQATPCRGLSRECGEDEQYSAENLRRISRSLSGTVVSEREEAP 1431
G H + T ++ RG S Q E SG S EA
Sbjct: 1837 G----HSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSG---SRHHEAS 1889
Query: 1432 VSSHSFDSSNVRKPLETGHRCSSSSSLPVIHD 1463
+ S S V + +G R S + V D
Sbjct: 1890 SRADSSRHSQVGQGQSSGPRTSRNQGSSVSQD 1921
Score = 42.4 bits (98), Expect = 0.004
Identities = 91/399 (22%), Positives = 140/399 (35%), Gaps = 41/399 (10%)
Query: 366 AEFQSYSRTCYDSEDSGREPSISSDTRTDSSTESYPYKHSHHESVV--SHFSSDSQGTVI 423
AE S T + SG + + S + S+ E + SHH+ S S G
Sbjct: 3592 AESSRQSGTHHAENSSGGQAASSHEQARSSAGERHG---SHHQQSADSSRHSGIGHGQAS 3648
Query: 424 YNVEND-----SMSQSSRDTGHLTDSECNQKHTSKKGSLIE-------RKRSSGRVRRKG 471
V + S SQ+S GH DS+ + + R RS+GR R G
Sbjct: 3649 SAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSG 3708
Query: 472 DEPQASGYHSEGETLKEKQAPRNASKPSSSTNRLRDFKETVSNMIHNRPSLASQT---NV 528
H + E+ + P + S + RD H+ T +
Sbjct: 3709 SFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSR------HSASQEGQDTIRGHP 3762
Query: 529 GSHCRGRGGDQPDKKPPRTLPLHSRDWEIESTSSESKSSSSSKYRPTWRPKRESLNIDSI 588
GS GR G ++ R+ S T+S+ +S +S + RE+ N +
Sbjct: 3763 GSRRGGRQGSYHEQSVDRSGHSGSHH---SHTTSQGRSDASHGQSGSRSASRETRNEEQ- 3818
Query: 589 FSKDKRKHCGYTQLSPFSEDSAKEFIPDEPSKPPSYDIKFGGPSPQYKRWGPARPGSHLL 648
S D +H G S E S + D S + G S + +R G +
Sbjct: 3819 -SGDGSRHSG----SRHHEASTQ---ADSSRHSQSGQGESAG-SRRSRRQGSSVSQDSDS 3869
Query: 649 EQHPRLIQRMESGYESSERNSSSPVSLDAALPESSNVYRDPSAKRSAGLVPSWRHIPKSH 708
E +P +R + SS S D + S+ +RD ++ + V S K H
Sbjct: 3870 EAYPEDSERRSESASRNHHGSSREQSRDGSRHPGSS-HRDTASHVQSSPVQSDSSTAKEH 3928
Query: 709 SS-SILEVDSTASMGGWTKSQPFSGEEISSKSELDELQE 746
S L DS G ++ P S +SE E Q+
Sbjct: 3929 GHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQSEGTERQK 3967
Score = 40.8 bits (94), Expect = 0.011
Identities = 244/1180 (20%), Positives = 369/1180 (31%), Gaps = 214/1180 (18%)
Query: 365 QAEFQSYSRTCYDSEDSGREPSISSDTRTDSSTESYPYKHSHHESVVSHFSSDSQGTVIY 424
Q+ +S SRT + E SG S ++ST + +HS S+G+
Sbjct: 2831 QSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQA------VQGQSEGSRRS 2884
Query: 425 NVENDSMSQSSRDTGHLTDSECNQKHTSKK--GSLIERKRSSGRVRRKGDEPQASGYHSE 482
+ S+SQ S GH DSE S+ GS E+ R R R E +A HS
Sbjct: 2885 RRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSA 2944
Query: 483 GETLKEKQAPRNASKPSSSTNRLRDFKETVSNMIHNRPSLASQTNVGSHCRGRGGDQPDK 542
+ +Q+ ++ SS ++ S+ S Q+ S G G Q
Sbjct: 2945 DSS---RQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQ--- 2998
Query: 543 KPPRTLPLHSRDWEIESTSSESKSSSSSKYRPTWRPKRESLNIDS-IFSKDKRKHCGYTQ 601
SS + S Y + E + DS S G Q
Sbjct: 2999 -----------------ASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQ 3041
Query: 602 LSPFSEDSAKEFIPDEPSKPPSYDIKFGGPSPQYKRW-GPARPGSHLLEQHPRLIQRMES 660
S + S Y + S W GP+ G R R E
Sbjct: 3042 QSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRG--------RQGSRHEQ 3093
Query: 661 GYESSERNSSSPVSLDAALPESSNVYRDPSAKRSAGLVPSWRHIPKSHSSSILEVDSTAS 720
+SS R+S+S D + P + R H S S T S
Sbjct: 3094 AQDSS-RHSASQYGQD-------TIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTS 3145
Query: 721 MGGWTKSQPFSGEEISSKSELDELQEEVARRAQEQELRRKREKELEAAKGFNPHPSRFMD 780
G S+ SG +S++ +E Q + R R E + H
Sbjct: 3146 QGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSV-----SRHHEASTHADISRHSQAV-- 3198
Query: 781 LDELQNQGRSDGFERSLQEAESVFEESLHLEQKGDCA--AALALCNEAISKLRLALHGAS 838
QG+S+G RS ++ SV ++S D + A N S + HG
Sbjct: 3199 ------QGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHG-- 3250
Query: 839 CSTHSRA----------LVDKKLQISIRKARSLQDRMQQQQSPQQPSQPSACLPTQAGTL 888
S H R+ D+ Q R A + Q S P ++
Sbjct: 3251 -SRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQS 3309
Query: 889 SQPTSEQPIPL-QVLLSQEAQLESGMDTEFGASSFFHSPASCHES---HSSLSPESSAPQ 944
+ + IP Q + G + S HS S +S H P + Q
Sbjct: 3310 ADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQ 3369
Query: 945 HSSPSRSALK------LLTSVEVDNIEPSAFHRQGLPKAPGWTEKNSHHSWEPLDAPEGK 998
S+ RS + L V SA G + + SHH A +
Sbjct: 3370 ESARDRSGGRSGRSGSFLYQVSTHEQSESA---HGRTRTSTGRRQGSHHE----QARDSS 3422
Query: 999 LQGSRCDNSSCSKLPPQEGRGIAQEQLFQEKKDPANPSPVMPGIATSERGDEHSLGCSPS 1058
+ + + P R Q +++ D + S TS+ + S G S S
Sbjct: 3423 RHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGS 3482
Query: 1059 NSSAQPSLPLYRTCHPIMPVASSFVLHCPDPVQKTNQCLQGQSLKTSLTLKVDRGSEETY 1118
S+++ Q N G + S + + ++
Sbjct: 3483 RSASR---------------------------QTRNDEQSGDGSRHSWSHHHEASTQADS 3515
Query: 1119 RPEFPSTKGLVRSLAEQFQRMQGVSM---RDSTGFKDRS--LSGSLRKNSSPSDSKPPFS 1173
S +G +S + R QG S+ DS G + S SGS +N S
Sbjct: 3516 SRHSQSGQG--QSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGS------- 3566
Query: 1174 QGQEKGHWPWAKQQSSLEGGDRPLSWEESTE---HSS-LALNSGLPNGETSSGGQPRLAE 1229
Q+ S +G P S E HS+ + SG + E SSGGQ +
Sbjct: 3567 -----------AQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSH 3615
Query: 1230 PDIYQEKLSQVRDVRSKDLGSSTDLGTSLPLDSWVNITRFCDSQLKHGAPRPGMKSSPHD 1289
Q R + GS S + + S ++ R S D
Sbjct: 3616 --------EQARSSAGERHGSHHQQSADSSRHSGIGHGQ-ASSAVRDSGHRGSSGSQASD 3666
Query: 1290 SHTCVTYPERNHILLH----PHWNQDTEQETSELES----------LYQASLQA------ 1329
S + + H PH Q + QE++ S LYQ S
Sbjct: 3667 SEGHSEDSDTQSVSAHGQAGPH--QQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAH 3724
Query: 1330 SQAGCSGWGQQ--------DTAWHPLSQTGS-------ADGMGRRLHSAHDPGLSKT--S 1372
+AG S G+Q D++ H SQ G G R S H+ + ++ S
Sbjct: 3725 GRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHS 3784
Query: 1373 TAEMEHGLHEARTVRTSQATPCRGLSRECGEDEQ----------------YSAENLRRIS 1416
+ H + R+ + + R SRE +EQ A++ R
Sbjct: 3785 GSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQ 3844
Query: 1417 RSLSGTVVSEREEAPVSSHSFDSSNVRKPLETGHRCSSSS 1456
+ S R SS S DS + P ++ R S+S
Sbjct: 3845 SGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESAS 3884
Score = 38.5 bits (88), Expect = 0.056
Identities = 134/646 (20%), Positives = 199/646 (30%), Gaps = 91/646 (14%)
Query: 365 QAEFQSYSRTCYDSEDSGREPSISSDTRTDSSTESYPYKHSHHESVVSHFSSDSQGTVIY 424
Q+ +S SR + + SG S ++S+ + +HS S G
Sbjct: 1858 QSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQ------GQSSGPRTS 1911
Query: 425 NVENDSMSQSSRDTGHLTDSECNQKHTSKK--GSLIERKRSSGRVRRKGDEPQASGYHS- 481
+ S+SQ S GH DSE S+ GS E+ R R E +A HS
Sbjct: 1912 RNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSA 1971
Query: 482 ---------EGETLKEKQAPRNASKPSSSTNRLRDFKETVSNMIHNRPSLASQTNVGSHC 532
E+ QA + + SS + + +R S S
Sbjct: 1972 DSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAV 2031
Query: 533 RGRGGDQPDKKPPRTLPLHSRDWEIESTSSESKS---------------------SSSSK 571
R G HS D + +S S++ K+ S S
Sbjct: 2032 RDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFL 2091
Query: 572 YRPTWRPKRESLNIDSIFSKDKRKHCGYTQLSPFSEDSAKEFIPDEPSKPPSYDIKFGGP 631
Y+ + + ES + S S R+ Y Q S SA + D G P
Sbjct: 2092 YQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQ---------EGQDTIRGHP 2142
Query: 632 SPQYKRWGPARPGSHLLEQHPRLIQRMESGYESSERNSSSPVSLDAALPESSNVYRDPSA 691
GP+R G Q + + SG S S S + R
Sbjct: 2143 -------GPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYD 2195
Query: 692 KRSAGLVPSWRHIPKSHSSSILEVDST-------ASMGGWTKSQPFSGEEISSKSELDEL 744
K +G RH H + DS+ G S+P G +S S+ +
Sbjct: 2196 KEQSG--DGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRP-RGSSVSQDSDSEGH 2252
Query: 745 QEEVARR-----------AQEQELRRKR----EKELEAAKGFNPHPSRFMDLDELQNQGR 789
E+ RR AQEQ R E A G + SR +N
Sbjct: 2253 SEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSG 2312
Query: 790 SDGFERSLQEAESVFE-ESLHLEQKGDCAAALALCN-EAISKLRLALHGASCSTHSRALV 847
Q S E H +Q D + + + +A S +R + H S + +
Sbjct: 2313 GQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQAS--- 2369
Query: 848 DKKLQISIRKARSLQDRMQQQQSPQQPSQPSACLPTQAGTLSQPTSEQPIPLQVLLSQEA 907
D + +S+ Q P Q S + AG + S QV +++
Sbjct: 2370 DSEGHSEDSDTQSVS--AHGQAGPHQQSHQESTRGRSAGRSGRSGS---FLYQVSTHEQS 2424
Query: 908 QLESG-MDTEFGASSFFHSPASCHESHSSLSPESSAPQHSSPSRSA 952
+ G T G H + S S S E H P S+
Sbjct: 2425 ESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSS 2470
Score = 37.4 bits (85), Expect = 0.12
Identities = 37/135 (27%), Positives = 54/135 (40%), Gaps = 11/135 (8%)
Query: 349 YADPQGTPVSTQDLPPQAEFQSYSRTCYDSEDSGREPSISSDTRTDSSTESYPYKHSHHE 408
+ PQG ++ Q+ +S SR + E SG S + ST + +HS
Sbjct: 1521 HTTPQGRSDASHG---QSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVG 1577
Query: 409 SVVSHFSSDSQGTVIYNVENDSMSQSSRDTGHLTDSECNQKHTSKK--GSLIERKRSSGR 466
+S G+ + S+SQ GH DSE + S+ GS E+ R R
Sbjct: 1578 Q------GESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSR 1631
Query: 467 VRRKGDEPQASGYHS 481
R E +AS HS
Sbjct: 1632 NPRSHQEDRASHGHS 1646
Score = 35.4 bits (80), Expect = 0.47
Identities = 91/448 (20%), Positives = 148/448 (33%), Gaps = 61/448 (13%)
Query: 365 QAEFQSYSRTCYDSEDSGREPSISSDTRTDSSTESYPYKHSHHESVVSHFSSDSQGTVIY 424
Q+ +S SR + E SG S ++ST++ +HS S G
Sbjct: 3479 QSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQ------GQSAGPRTS 3532
Query: 425 NVENDSMSQSSRDTGHLTDSE--CNQKHTSKKGSLIERKRSSGRVRRKGDEPQASGYHSE 482
+ S+SQ S GH DSE + +GS E+ R R E +A HS
Sbjct: 3533 RNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSA 3592
Query: 483 GETLKE--KQAPRNASKPSSSTNRLRDFKETVSNMIHNRPSLASQTNVG----------- 529
+ + A ++ ++S++ + H++ S S + G
Sbjct: 3593 ESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVR 3652
Query: 530 -SHCRGRGGDQPDKKPPRTLPLHSRDWEIESTSSESKS---------------------S 567
S RG G Q HS D + +S S+ ++ S
Sbjct: 3653 DSGHRGSSGSQASDSEG-----HSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRS 3707
Query: 568 SSSKYRPTWRPKRESLNIDSIFSKDKRKHCGYTQLSPFSEDSAKEFIPDEPSKPPSYDIK 627
S Y+ + + ES + + S R+ + Q S SA + D P +
Sbjct: 3708 GSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPG--SR 3765
Query: 628 FGGPSPQYKRWGPARPGSHLLEQHPRLIQRMESGYESSERNSSSPVSLDAALPESSNVYR 687
GG Y R G H H + S + S S A E+ N +
Sbjct: 3766 RGGRQGSYHEQSVDRSG-HSGSHHSHTTSQGRSDASHGQSGSRS------ASRETRNEEQ 3818
Query: 688 DPSAKRSAGLVPSWRHIPKSHSSSILEVDSTASMGGWTKSQPFSGEEISSKSELDELQEE 747
R +G S H + + S S ++ G +S S+ + E+
Sbjct: 3819 SGDGSRHSG---SRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPED 3875
Query: 748 VARRAQEQELRRKREKELEAAKGFNPHP 775
RR+ E R E ++ + HP
Sbjct: 3876 SERRS-ESASRNHHGSSREQSRDGSRHP 3902
Score = 33.9 bits (76), Expect = 1.4
Identities = 143/679 (21%), Positives = 238/679 (35%), Gaps = 85/679 (12%)
Query: 370 SYSRTCYDSEDSG-REPSISSDTRTDSSTE---SYP---YKHSHHESV-VSHFSSDSQGT 421
S+ + S SG R SS +T SS E S P + H +S S S+ +G
Sbjct: 345 SHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQ 404
Query: 422 VIYNVEN-----DSMSQSSRDTGHLTDSECNQKHTSKKGSLIERKRSSGRVRRKGDEPQA 476
V + S SQ+S GH +S+ K L ++ R G+
Sbjct: 405 ASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGR 464
Query: 477 SGYHSEGETLKEKQAPRNASKPSSSTNRLRDFKETVSNMIHNRPSLASQTNV----GSHC 532
SG + E+ + +S+ R E + + S Q + GS
Sbjct: 465 SGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSR 524
Query: 533 RGRGGDQPDKKPPRTLPLHSRDWEIESTSSESKSSSSSKYRPTWRPKRESLNIDSIFSKD 592
GR G ++ R+ S T+S+ +S +S + R++ N + S D
Sbjct: 525 GGRQGSHHEQSVNRSGHSGSHH---SHTTSQGRSDASHGQSGSRSASRQTRNEEQ--SGD 579
Query: 593 KRKHCG--YTQLSPFSEDSAKEFIPDEPSKPP----------SYDIKFGGPSPQYKRW-- 638
+H G + + S ++ S + S P S D G S +RW
Sbjct: 580 GTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSG 639
Query: 639 -------GPARPGSHLLEQHPRLIQRMESGY---ESSERNSSSPVSLDAALPESSNVYRD 688
G A+ S +HPR +G+ S R S + + +++ ++++ +
Sbjct: 640 SASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHE- 698
Query: 689 PSAKRSAGLVPSWRHIPKSHSSSILEVDSTASMGGWTKSQPFSGEEISSKSELDELQEEV 748
A+ SAG RH +S SS S G + + SG SS S+ + +
Sbjct: 699 -QARSSAGERHGSRHQLQSADSS---RHSGTGHGQASSAVRDSGHRGSSGSQATDSE--- 751
Query: 749 ARRAQEQELRRKREKELEAAKGFNPHPSRFMDLDELQNQGRSDGFERSLQEAESVFEESL 808
+ + ++ G H Q R ERS + +++ S
Sbjct: 752 ---------GHSEDSDTQSVSG---HGQAGHHQQSHQESARDRSGERSRRSGSFLYQVST 799
Query: 809 HLEQKGDCAAALALCNEAISKLRLALHGASCSTHSRALVDKKLQISIRKARSLQDRMQQQ 868
H + + + +R H +SR + Q +IR R +Q
Sbjct: 800 HKQSESSHG-----WTGPSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQG 854
Query: 869 QSPQQPSQPSACLPT-QAGTLSQPTSEQPIPLQVLLSQEAQLESGMDTEFGASSFFHSPA 927
+Q S + + T SQ S+ S + + G+ HS +
Sbjct: 855 SHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSR---HSGS 911
Query: 928 SCHE--SHSSLSPESSAPQ-HSSPSRSALKLLTSVEVDNIEPSAFHRQGLPKAPGWTEKN 984
HE SH+ +S S A Q S SR++ + +SV D+ S H + + G +N
Sbjct: 912 RHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDS--DSEGHSEDSERWSGSASRN 969
Query: 985 SHHSWEPLDAPEGKLQGSR 1003
S A E GSR
Sbjct: 970 HRGS-----AQEQSRHGSR 983
>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
Length = 1758
Score = 50.8 bits (120), Expect = 1e-05
Identities = 87/415 (20%), Positives = 159/415 (38%), Gaps = 41/415 (9%)
Query: 382 GREPSISSDTRTD-SSTESYPYKHSHHESVVSHFSSDSQGTVIYNVENDSMSQSSRDTGH 440
G+ S+ + T S+ YP K S + F+ D +I + S + +S + G
Sbjct: 1309 GKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGK 1368
Query: 441 LTDS-----ECNQKHTSKKGSLIERKRSSGRVRRKGDEPQASGYHSEGETLKEKQAPRNA 495
D E K + E++ + R+ +G+ S E T + + R +
Sbjct: 1369 TKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRAS 1428
Query: 496 SKPSSSTNRLR----DFKETVSNMIHNRPS-LASQTNVGSHCRGRGGDQPDK-KPPRTLP 549
S + NR + D +E S+ + + L + + S + Q +K + R LP
Sbjct: 1429 SNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLP 1488
Query: 550 LHSRDWEIESTSSESKSSSSSKYRPTW---RPKRESLNIDSIFSKDKRKHCGYTQLSPFS 606
+S SS S+ ++ T+ RP E+ ++D KD+ KH + + S
Sbjct: 1489 KKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKES 1548
Query: 607 EDSAKEFIPDEPSKPPSYDIKFG-------GPSPQYKRWGPARPGSHLLEQHPRLIQRME 659
+ +I + P + G P PQ +R S L + E
Sbjct: 1549 SGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSH--SSRLSSDLTRETD------E 1600
Query: 660 SGYESSERNSSSPVSLDAALPESS-NVYRD------PSAKRS---AGLVPSWRHIPKSHS 709
+ +E S S ++ ESS N+ +D AK S A +V +SHS
Sbjct: 1601 AAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHS 1660
Query: 710 S-SILEVDSTASMGGWTKSQPFSGEEISSKSELDELQEEVARRAQEQELRRKREK 763
S S+ S + G T+S S S+ + +++ ++ ++ + +K +K
Sbjct: 1661 SPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKK 1715
>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens]
Length = 1792
Score = 50.8 bits (120), Expect = 1e-05
Identities = 87/415 (20%), Positives = 159/415 (38%), Gaps = 41/415 (9%)
Query: 382 GREPSISSDTRTD-SSTESYPYKHSHHESVVSHFSSDSQGTVIYNVENDSMSQSSRDTGH 440
G+ S+ + T S+ YP K S + F+ D +I + S + +S + G
Sbjct: 1343 GKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGK 1402
Query: 441 LTDS-----ECNQKHTSKKGSLIERKRSSGRVRRKGDEPQASGYHSEGETLKEKQAPRNA 495
D E K + E++ + R+ +G+ S E T + + R +
Sbjct: 1403 TKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRAS 1462
Query: 496 SKPSSSTNRLR----DFKETVSNMIHNRPS-LASQTNVGSHCRGRGGDQPDK-KPPRTLP 549
S + NR + D +E S+ + + L + + S + Q +K + R LP
Sbjct: 1463 SNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLP 1522
Query: 550 LHSRDWEIESTSSESKSSSSSKYRPTW---RPKRESLNIDSIFSKDKRKHCGYTQLSPFS 606
+S SS S+ ++ T+ RP E+ ++D KD+ KH + + S
Sbjct: 1523 KKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKES 1582
Query: 607 EDSAKEFIPDEPSKPPSYDIKFG-------GPSPQYKRWGPARPGSHLLEQHPRLIQRME 659
+ +I + P + G P PQ +R S L + E
Sbjct: 1583 SGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSH--SSRLSSDLTRETD------E 1634
Query: 660 SGYESSERNSSSPVSLDAALPESS-NVYRD------PSAKRS---AGLVPSWRHIPKSHS 709
+ +E S S ++ ESS N+ +D AK S A +V +SHS
Sbjct: 1635 AAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHS 1694
Query: 710 S-SILEVDSTASMGGWTKSQPFSGEEISSKSELDELQEEVARRAQEQELRRKREK 763
S S+ S + G T+S S S+ + +++ ++ ++ + +K +K
Sbjct: 1695 SPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKK 1749
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 44.7 bits (104), Expect = 8e-04
Identities = 128/691 (18%), Positives = 219/691 (31%), Gaps = 44/691 (6%)
Query: 377 DSEDSGREPSISSDTRTDSSTESYPYKHSHHESVVSHFSSDSQGTVIYNVENDSMSQSSR 436
DS DS S SSD+ S++S S S SSDS + N + S S S
Sbjct: 553 DSSDSSNS-SDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSS 611
Query: 437 DTGHLTDSECNQKHTSKKGSLIERKRSSGRVRRKGDEPQASGYHSEGETLKEKQAPRNAS 496
D+ +DS ++ +SK S SS + S S+ + N+S
Sbjct: 612 DSSDSSDSSDSKSDSSKSES-----DSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSS 666
Query: 497 KPSSSTNRLRDFKETVSNMIHNRPSLASQTNVGSHCRGRGGDQPDKKPPRTLPLHSRDWE 556
S S+ D ++ S+ + S +S ++ S+ + D
Sbjct: 667 DSSDSS----DSSDSSSSSDSSNSSDSSDSSDSSN----SSESSDSSDSSDSDSSDSSDS 718
Query: 557 IESTSSESKSSSSSKYRPTWRPKRESLNIDSIFSKDKRKHCGYTQLSPFSEDSAKEFIPD 616
S SS+S SS+SS + S + DS S D + S S+ S D
Sbjct: 719 SNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSD 778
Query: 617 EPSKPPSYDIKFGGPSPQYKRWGPARPGSHLLEQHPRLIQRMESGYESSERNSSSPVSLD 676
+ S D S S S +S S S D
Sbjct: 779 SSNSSDSNDSSNSSDSSD------------------------SSNSSDSSNSSDSSDSSD 814
Query: 677 AALPESSNVYRDPSAKRSAGLVPSWRHIPKSHSSSILEVDSTASMGGWTKSQPFSGEEIS 736
++ +SSN ++ S+ S S SS + DS+ S + S
Sbjct: 815 SSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSS 874
Query: 737 SKSELDELQE--EVARRAQEQELRRKREKELEAAKGFNPHPSRFMDLDELQNQGRSDGFE 794
+ S+ + + E + + + + + + + D ++ SD
Sbjct: 875 NSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSN 934
Query: 795 RSLQEAESVFEESLHLEQKGDCAAALALCNEAISKLRLALHGASCSTHSRALVDKKLQIS 854
S S +S D + + N + S + + S S + S
Sbjct: 935 SSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDS 994
Query: 855 IRKARSLQDRMQQQQSPQQPSQPSACLPTQAGTLSQPTSEQPIPLQVLLSQEAQLESGMD 914
+ S S S S+ + + S +S+ S ++ S
Sbjct: 995 SDSSDSSNSSDSSDSSDSSDSSNSS--DSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1052
Query: 915 TEFGASSFFHSPASCHESHSSLSPESSAPQHSSPSRSALKLLTSVEVDNIEPSAFHRQGL 974
+S S S S SS S +SS SS S + S + + S+
Sbjct: 1053 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1112
Query: 975 PKAPGWTEKNSHHSWEPLDAPEGKLQGSRCDNSSCSKLPPQEGRGIAQEQLFQEKKDPAN 1034
+ NS S + D+ + + D+S S+ + + + D ++
Sbjct: 1113 DSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDS--SDSSDSSD 1170
Query: 1035 PSPVMPGIATSERGDEHSLGCSPSNSSAQPS 1065
S +S+ D S +S + S
Sbjct: 1171 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1201
Score = 43.9 bits (102), Expect = 0.001
Identities = 133/702 (18%), Positives = 218/702 (31%), Gaps = 41/702 (5%)
Query: 370 SYSRTCYDSEDSGREPSISSDTRTDSSTESYPYKHS--HHESVVSHFSSDSQGTVIYNVE 427
S S + DS+ S + S SSD+ + S+ S S +S S SSDS+ +
Sbjct: 572 SDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSES 631
Query: 428 NDSMSQSSRDTGHLTDSECNQKHTSKKGSLIERKRSSGRVRRKGDEPQASGYHSEGETLK 487
+ S S S D+ S+ + S S S D +S + ++
Sbjct: 632 DSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSD 691
Query: 488 EKQAPRNASKPSSSTNRLRDFKETVSNMIHNRPSLASQTNVGSHCRGRGGDQPDKKPPRT 547
+ ++ SS + D ++ + N S + S D D
Sbjct: 692 SSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSS- 750
Query: 548 LPLHSRDWEIESTSSESKSSSSSKYRPTWRPKRESLNIDSIFSKDKRKHCGYTQLSPFSE 607
+S D S SS S SS S S + DS S D + S S
Sbjct: 751 ---NSSDSSDSSDSSNSSDSSDS--------SDSSDSSDSSNSSDSNDSSNSSDSSDSSN 799
Query: 608 DSAKEFIPDEPSKPPSYDIKFGGPSPQYKRWGPARPGSHLLEQHPRLIQRMESGYESSER 667
S D S D S + S+ + S +SS R
Sbjct: 800 SSDSSNSSDSSDSSDSSDSDSSNSSDS-SNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNR 858
Query: 668 NSSSPVSLDAALPESSNVYRDPSAKRSAGLVPSWRHIPKSHSSSILEVDSTASMGGWTKS 727
+ SS S + +SSN + S S S+SS DS+ S S
Sbjct: 859 SDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSS 918
Query: 728 QPFSGEEISSKSE----LDELQEEVARRAQEQELRRKREKELEAAKGFNPHPSRFMDLDE 783
E S+ S+ D + + + +++ + S D +
Sbjct: 919 NSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSD 978
Query: 784 LQNQGRSDGFERSLQEAESVFEESLHLEQKGDCAAALALCNEAISKLRLALHGASCSTHS 843
N SD + S S +S + D + + N + S +S S++S
Sbjct: 979 SSNS--SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSS------NSSDSSNS 1030
Query: 844 RALVDKKLQISIRKARSLQDRMQQQQSPQQPSQPSACLPTQAGTLSQPTSEQPIPLQVLL 903
D + D S + + + S +
Sbjct: 1031 SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD---------- 1080
Query: 904 SQEAQLESGMDTEFGASSFFHSPASCHESHSSLSPESSAPQHSSPSRSALKLLTSVEVDN 963
S E+ S +S S S S SS S +SS +SS S + S + N
Sbjct: 1081 SSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 1140
Query: 964 IEPSAFHRQGLPKAPGWTEKNSHHSWEPLDAPEGKLQGSRCDNSSCSKLPPQEGRGIAQE 1023
S+ + + +S S + D+ + + D+S S + +
Sbjct: 1141 SSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSD 1200
Query: 1024 QLFQEKKDPANPSPVMPGIATSERGDEHSLGCSPSNSSAQPS 1065
+ D ++ S +S+ D S S SN S+ S
Sbjct: 1201 S--SDSSDSSDSSDSSDSSDSSDSSD--SSDSSDSNESSDSS 1238
Score = 41.2 bits (95), Expect = 0.009
Identities = 56/251 (22%), Positives = 86/251 (34%), Gaps = 16/251 (6%)
Query: 359 TQDLPPQAEFQSYSRTCYDSEDSGREPSISSDTRTDSSTESYPYKHSHHESVVSHFSSDS 418
+ D ++ S + S+ S S +S +DSS S + +S S SSDS
Sbjct: 776 SSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDS 835
Query: 419 QGTVIYNVENDSMSQSSRDTGHLTDSECNQKHTSKKGSLIERKRSSGRVRRKGDEPQASG 478
N S S S D+ +DS+ + + S S S D +S
Sbjct: 836 --------SNSSDSSDSSDSSDGSDSDSSNRSDSSNSS---DSSDSSDSSNSSDSSDSSD 884
Query: 479 YHSEGETLKEKQAPRNASKPSSSTNRLRDFKETVSNMIHNRPSLASQTNVGSHCRGRGGD 538
+ + + ++ SS ++ D ++ SN + S S N S D
Sbjct: 885 SNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDS-SNSSDSSESSNSSDNSNSSDSSNSSD 943
Query: 539 QPDKKPPRTLPLHSRDWEIESTSSESKSSSSSKYRPTWRPKRESLNIDSIFSKDKRKHCG 598
D +S D S SS S SS S + S + DS S D
Sbjct: 944 SSDSSDSS----NSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSD 999
Query: 599 YTQLSPFSEDS 609
+ S S+ S
Sbjct: 1000 SSNSSDSSDSS 1010
Score = 39.3 bits (90), Expect = 0.033
Identities = 53/260 (20%), Positives = 87/260 (33%), Gaps = 1/260 (0%)
Query: 350 ADPQGTPVSTQDLPPQAEFQSYSRTCYDSEDSGREPSISSDTRTDSSTESYPYKHSHHES 409
+D + S++ S S DS +S S SS++ S + + +S
Sbjct: 690 SDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDS 749
Query: 410 VVSHFSSDSQGTVIYNVENDSMSQSSRDTGHLTDSECNQKHTSKKGSLIERKRSSGRVRR 469
S SSDS + + +DS S SS + S+ N S S S
Sbjct: 750 SNSSDSSDSSDSSNSSDSSDS-SDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSD 808
Query: 470 KGDEPQASGYHSEGETLKEKQAPRNASKPSSSTNRLRDFKETVSNMIHNRPSLASQTNVG 529
D +S S + + + S SS ++ D + + NR ++ ++
Sbjct: 809 SSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSS 868
Query: 530 SHCRGRGGDQPDKKPPRTLPLHSRDWEIESTSSESKSSSSSKYRPTWRPKRESLNIDSIF 589
+S D S SS+S SS SS + S + +S
Sbjct: 869 DSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSN 928
Query: 590 SKDKRKHCGYTQLSPFSEDS 609
S D + S S+ S
Sbjct: 929 SSDNSNSSDSSNSSDSSDSS 948
Score = 38.5 bits (88), Expect = 0.056
Identities = 86/393 (21%), Positives = 129/393 (32%), Gaps = 21/393 (5%)
Query: 359 TQDLPPQAEFQSYSRTCYDSEDSGREPSISSDTRTDSSTESYPYKHSHHESVVSHFSSDS 418
+ D ++ S + +S S S S +DSS S S +S S SSDS
Sbjct: 914 SSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSS--DSSNSSDSSDS 971
Query: 419 QGTVIYNVENDSMSQSSRDTGHLTDSECNQKHTSKKGSLIERKRSSGRVRRKGDEPQASG 478
+ + N S S S D+ +DS + + S S+ + S
Sbjct: 972 NSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSS 1031
Query: 479 YHSEGETLKEKQAPRNASKPSSSTNRLRDFKETVSNMIHNRPSLASQTNVGSHCRGRGGD 538
S+ + ++S S S+N S+ + S S + S D
Sbjct: 1032 DSSDSSDSSDSSDSSDSSDSSDSSN-----SSDSSDSSDSSDSSDSSDSSDSSDSSESSD 1086
Query: 539 QPDKKPPRTLPLHSRDWEIESTSSESK-SSSSSKYRPTWRPKRESLNIDSIFSKDKRKHC 597
D +S D S SS+S SS SS + S + DS S D
Sbjct: 1087 SSDSS-------NSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1139
Query: 598 GYTQLSPFSEDSAKEFIPDEPSKPPSYDIKFGGPSPQYKRWGPARPGSHLLEQHPRLIQR 657
+ S SE S D S D S + S +
Sbjct: 1140 NSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1199
Query: 658 MESGYESSERNSSSPVSLDAALPESSNVYRDPSAKRSAGLVPSWRHIPKSHSS----SIL 713
S S +S S S D++ +SS+ + S+ S S+SS S
Sbjct: 1200 DSSDSSDSSDSSDSSDSSDSS--DSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSD 1257
Query: 714 EVDSTASMGGWTKSQPFSGEEISSKSELDELQE 746
DST+ + SQ SG ++ S+ D E
Sbjct: 1258 SSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSE 1290
Score = 37.0 bits (84), Expect = 0.16
Identities = 124/697 (17%), Positives = 221/697 (31%), Gaps = 26/697 (3%)
Query: 378 SEDSGREPSISSDTRTDSSTESYPYKHSHHESVVSHFSSDSQGTVIYNVENDSMSQSSRD 437
++D+ E +S +R D+S S ES + SDS+G + ++ S + +S
Sbjct: 474 NDDANSESDNNSSSRGDASYNS-------DESKDNGNGSDSKGAEDDDSDSTSDTNNSDS 526
Query: 438 TGHLTD-SECNQKHTSKKGSLIERKRSSGRVRRKGDEPQASGYHSEGETLK------EKQ 490
G+ + ++ N K S KG S D +S S +
Sbjct: 527 NGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSD 586
Query: 491 APRNASKPSSSTNRLRDFKETVSNMIHNRPSLASQTNVGSHCRGRGGDQPDKKPPRTLPL 550
+ ++ SS ++ D ++ + + S +S + S D K +
Sbjct: 587 SSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSN 646
Query: 551 HSRDWEIESTSSESKSSSSSKYRPTWRPKRESLNIDSIFSKDKRKHCGYTQLSPFSEDSA 610
S + +S S SS+SS + S + DS S D + S S+ S
Sbjct: 647 SSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSD 706
Query: 611 KEFIPDEPSKPPSYDIKFGGPSPQYKRWGPARPGSHLLEQHPRLIQRMESGYESSERNSS 670
S S S + S + S S +S
Sbjct: 707 SSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSD 766
Query: 671 SPVSLDAA-LPESSNVYRDPSAKRSAGLVPSWRHIPKSHSS-SILEVDSTASMGGWTKSQ 728
S S D++ +SSN + S+ S S+SS S DS+ S +
Sbjct: 767 SSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDS 826
Query: 729 PFSGEEISSKSELDELQEEVARRAQEQELRRKREKELEAAKGFNPHPSRFMDLDELQNQG 788
S + S + D + + + + + + + S D + +
Sbjct: 827 SNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSN 886
Query: 789 RSDGFERSLQEAESVFEESLHLEQKGDCAAALALCNEAISKLRLALHGASCSTHSRALVD 848
S S + S +S D + + + + S +S S++S D
Sbjct: 887 ESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSD 946
Query: 849 KKLQISIRKARSLQDRMQQQQSPQQPSQPSACLPTQAGTLSQPTSEQPIPLQVLLSQEAQ 908
S + S S S S + + S +S+ S ++
Sbjct: 947 -----SSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1001
Query: 909 LESGMDTEFGASSFFHSPASCHESHSSLSPESSAPQHSSPSRSALKLLTSVEVDNIEPSA 968
S +S +S S + S SS S +SS SS S + S + N S+
Sbjct: 1002 NSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1061
Query: 969 FHRQGLPKAPGWTEKNSHHSWEPLDAPEGKLQGSRCDNSSCSKLPPQEGRGIAQEQLFQE 1028
+ +S S E D+ + D+S S + + +
Sbjct: 1062 DSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSS-----DSSDSSDSSDSSD 1116
Query: 1029 KKDPANPSPVMPGIATSERGDEHSLGCSPSNSSAQPS 1065
D +N S +S+ D + S +S + S
Sbjct: 1117 SSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDS 1153
Score = 36.2 bits (82), Expect = 0.28
Identities = 148/863 (17%), Positives = 268/863 (31%), Gaps = 49/863 (5%)
Query: 389 SDTRTDSSTE---SYPYKHSHHESVVSHFSSDSQGTVIYNVENDSMSQS----------S 435
S+T +DS+++ SY + + + S +S G N E+D+ S S S
Sbjct: 439 SNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDES 498
Query: 436 RDTGHLTDSECNQKHTSKKGSLIERKRSSGRVRR-----------KGDEPQASGYHSEGE 484
+D G+ +DS+ + S S S+G KG + S+
Sbjct: 499 KDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSS 558
Query: 485 TLKEKQAPRNASKPSSSTNRLRDFKETVSNMIHNRPSLASQTNVGSHCRGRGGDQPD--- 541
+ ++ S+++ D ++ S+ + S S + S D D
Sbjct: 559 NSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSD 618
Query: 542 ----KKPPRTLPLHSRDWEIESTSSESKSSSSSKYRPTWRPKRESLNIDSIFSKDKRKHC 597
K S D + +S SS+S SS SS + S + DS S D
Sbjct: 619 SSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSS 678
Query: 598 GYTQLSPFSEDSAKEFIPDEPSKPPSYDIKFGGPSPQYKRWGPARPGSHLLEQHPRLIQR 657
+ S S+ S + S D S S
Sbjct: 679 SSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSS 738
Query: 658 MESGYESSERNSSSPVSLDAALPESSNVYRDPSAKRSAGLVPSWRHIPKSHSSSILEVDS 717
S S +S+S S D++ +SSN + S+ S + SS+ DS
Sbjct: 739 NSSDSSDSSDSSNSSDSSDSS--DSSNSSDSSDSSDSSDSSDSSNSSDSNDSSN--SSDS 794
Query: 718 TASMGGWTKSQPFSGEEISSKSELDELQEEVARRAQEQELRRKREKELEAAKGFNPHPSR 777
+ S S + S S+ D + + + +++ + S
Sbjct: 795 SDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSD 854
Query: 778 FMDLDELQNQGRSDGFERSLQEAESVFEESLHLEQKGDCAAALALCNEAISKLRLALHGA 837
+ + N SD + S S +S + + + + N + S + + +
Sbjct: 855 SSNRSDSSNS--SDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSS 912
Query: 838 SCSTHSRALVDKKLQISIRKARSLQDRMQQQQSPQQPSQPSACLPTQAGTLSQPTSEQPI 897
S S + + S + S S S S+ + + + S
Sbjct: 913 DSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSN 972
Query: 898 PLQVLLSQEAQLESGMDTEFGASSFFHSPASCHESHSSLSPESSAPQHSSPSRSALKLLT 957
S ++ S +S S S + S SS S +SS +SS S ++
Sbjct: 973 SSD---SSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSN 1029
Query: 958 SVEVDNIEPSAFHRQGLPKAPGWTEKNSHHSWEPLDAPEGKLQGSRCDNSSCSKLPPQEG 1017
S + + S+ + NS S + D+ + D+S S+
Sbjct: 1030 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSD 1089
Query: 1018 RGIAQEQLFQEKKDPANPSPVMPGIATSERGDEHSLGCSPSNSSAQPSLPLYRTCHPIMP 1077
+ + + D ++ S +S+ D + S +S + S +
Sbjct: 1090 SSNSSDS--SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDS 1147
Query: 1078 VASSFVLHCPDPVQKTNQCLQGQSLKTSLTLKVDRGSEETYRPEFPSTKGLVRSLAEQFQ 1137
SS D ++ S +S + S+ + + + ++
Sbjct: 1148 SESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS-------SDSSD 1200
Query: 1138 RMQGVSMRDSTGFKDRSLSGSLRKNSSPSDSKPPFSQGQEKGHWPWAKQQSSLEGGDRPL 1197
DS+ D S S +S SDS + S + D
Sbjct: 1201 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSD 1260
Query: 1198 SWEESTEHSSLALNSGLPNGETS 1220
S +S + S SG N S
Sbjct: 1261 STSDSNDESDSQSKSGNGNNNGS 1283
Score = 33.1 bits (74), Expect = 2.3
Identities = 22/80 (27%), Positives = 34/80 (42%)
Query: 377 DSEDSGREPSISSDTRTDSSTESYPYKHSHHESVVSHFSSDSQGTVIYNVENDSMSQSSR 436
DS DS S + S++S S + S S S S T N E+DS S+S
Sbjct: 1218 DSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGN 1277
Query: 437 DTGHLTDSECNQKHTSKKGS 456
+ +DS+ + + + S
Sbjct: 1278 GNNNGSDSDSDSEGSDSNHS 1297
>gi|153251865 hypothetical protein LOC84226 [Homo sapiens]
Length = 1984
Score = 42.4 bits (98), Expect = 0.004
Identities = 104/495 (21%), Positives = 176/495 (35%), Gaps = 54/495 (10%)
Query: 414 FSSDSQGTVIYNVENDSMSQSSRDTGHLTDSECNQKHTSKKGSLIERKRSSGRVRRKGDE 473
F + S G + V+ DS S+S ++ S K+ S G+ ++ + GR+
Sbjct: 1466 FQTASVGQPLRTVQKDSSSRSKKNFYRNETSSQESKNLSTPGTRVQAR---GRILP--GS 1520
Query: 474 PQASGYHSEGETLKEKQAPRNASKPSSSTNRLRDFKETVSNMIHNRPSLASQTNVGSHCR 533
P +H LK+K + + PS R S + PS + + +
Sbjct: 1521 PVKRTWHRH---LKDKLTHKEHNHPSFYRERT---PRGPSERTRHNPSWRNHRSPSERSQ 1574
Query: 534 GRGGDQPDKKPPRTLPLHSRDWEIESTSSESKSSSSSKYRPTWR----------PKRE-- 581
++ P + S S S+ + SS +WR P+R
Sbjct: 1575 RSSLERRHHSPSQ-----------RSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCH 1623
Query: 582 SLNIDSIFSKDKRKHCGYTQLSPFSEDSAKEFIPDEPSKPPSYDIKFGGPSPQYKRWGPA 641
SL+ + S +R H G +Q S P E S S + + PS + R GP+
Sbjct: 1624 SLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHR-GPS 1682
Query: 642 RPG--SHLLEQHPRLIQRMESGYESSERNSSSPVSLDAALPESSNVYRDPSAKRSAGLVP 699
S +H QR G SER SP P + +R PS +
Sbjct: 1683 ERSHCSPSERRHRSPSQRSHRG--PSERRHHSPSKRSHRSP-ARRSHRSPSERSHHSPSE 1739
Query: 700 SWRHIP---KSHSSSILEVDSTASMGGWTKSQ--PFSGEEISSKSELDELQEEVARRAQE 754
H P + HS S S + + S+ S E S ++ + R+
Sbjct: 1740 RSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHH 1799
Query: 755 QELRRKREKELEAAKGFNPHPSRFMDLDELQNQGRSDGFERSLQEAESVFEESLHLE--Q 812
R+R LE ++ S + ++ R + + S E+S HL +
Sbjct: 1800 SPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKS-HLSPLE 1858
Query: 813 KGDCAAALALCNEAISKLRLALHGASCSTHSRALVDKKLQISIRKARSLQDRMQQQQSPQ 872
+ C+ + + + K H S +H ++ + S R RS +R + S
Sbjct: 1859 RSRCSPSERRGHSSSGK---TCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEM 1915
Query: 873 QPSQPSA---CLPTQ 884
+P +PS C P++
Sbjct: 1916 RPGRPSGRNHCSPSE 1930
Score = 33.9 bits (76), Expect = 1.4
Identities = 61/260 (23%), Positives = 86/260 (33%), Gaps = 24/260 (9%)
Query: 378 SEDSGREPSISSDTRTDSSTESYPYKHSHHESVVSHFSSDSQGTVIYNVENDSMSQSSRD 437
S+ S R P+ S + P + SHH S S+ + E S S R
Sbjct: 1714 SKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSER- 1772
Query: 438 TGHLTDSECNQKHTSKKG--SLIERKRSSGRVRRKGDEPQASGYHSEGETLKEKQAPRNA 495
H + SE S+K S ER S RR+ P HS E + R +
Sbjct: 1773 -RHRSPSERRHHSPSEKSHHSPSERSHHSPSERRR-HSPLERSRHSLLERSHRSPSERRS 1830
Query: 496 SKP-SSSTNRLRDFKETVSNMIHNRPSLASQTNV----GSHCRGRGGDQPDKKPPRTLPL 550
+ S R+ + + S H P S+ + G G+ P ++ R+ P
Sbjct: 1831 HRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRS-PS 1889
Query: 551 HSRDWEIESTSSESKSSSSSKYRPTWRPKRESLNIDSIFSKDKRKHCG---YTQLSPFSE 607
R S S + RP R S R HC ++ SP E
Sbjct: 1890 GMRQGRTSERSHRSSCERTRHSPSEMRPGRPS----------GRNHCSPSERSRRSPLKE 1939
Query: 608 DSAKEFIPDEPSKPPSYDIK 627
F + PS S D K
Sbjct: 1940 GLKYSFPGERPSHSLSRDFK 1959
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 41.6 bits (96), Expect = 0.007
Identities = 48/228 (21%), Positives = 94/228 (41%), Gaps = 13/228 (5%)
Query: 378 SEDSGREPSISSDTRTDSSTESYPYKHSHHESVVSHFSSDSQGTVIYNVENDSMSQSSRD 437
S+++ + S+ T T+ K S ES S + V NV+ D + +
Sbjct: 269 SQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKK 328
Query: 438 TGHLTDSECNQKHTSKKGSLIERKRSSGRVRRKGDEPQASGYHSE-GETLKEKQAPRNAS 496
TD+E +K + ++K+ ++K + +E G+ + RN
Sbjct: 329 DTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLK 388
Query: 497 KPSSSTNRLRDFKETVSNMIHNRPSLASQTNVGSHCRGRGGDQPDKKPPRTLPLHSRDWE 556
K S + ++ +D K+ S S++ + S + ++ DKK +T S +
Sbjct: 389 KASKNDDKKKDAKKITF-------STDSESELESK-ESQKDEKKDKKDSKTDNKKSVKND 440
Query: 557 IESTSSESKSSSSSK--YRPTWRPKRESLNIDSIFSKDKRKHCGYTQL 602
EST ++S+ SK + + K++S D KD +K+ T++
Sbjct: 441 EESTDADSEPKGDSKKGKKDEKKGKKDSKKDDK--KKDAKKNAESTEM 486
>gi|148806908 fibronectin type III domain containing 1 [Homo sapiens]
Length = 1894
Score = 41.2 bits (95), Expect = 0.009
Identities = 100/427 (23%), Positives = 156/427 (36%), Gaps = 62/427 (14%)
Query: 358 STQDLPPQAEFQS-YSRTCYDSEDSGREPSISSDTRTDSSTESYPYKHSHHESVVSHFSS 416
S++ LP Q S S+ D ED+ P+ +S+ + S+ S SV SH SS
Sbjct: 726 SSRLLPTQPHLSSPLSKGGKDGEDA---PATNSNAPSRSTMSS---------SVSSHLSS 773
Query: 417 DSQGTVIYNVENDSMSQSSRDTGHLTDSECNQKHTSKKGSLIERKRSSGRVRRKGDEPQA 476
+Q ++ S ++ D E + + + +SG +P A
Sbjct: 774 RTQ-------VSEGAEASDGESHGDGDREDGGRQAEATAQTLRARPASGHFHLLRHKPFA 826
Query: 477 SGYHSEGETLKEKQAPRNASKPSSSTNRLRDFKETVSNMIHNRPSLASQTNVGSHCRGRG 536
+ S + PR +PSSS + TV + H R S ++ G
Sbjct: 827 ANGRSPSR-FSIGRGPR--LQPSSSP------QSTVPSRAHPRVPSHSDSHP-KLSSGIH 876
Query: 537 GDQPDKKP-PRTL-----------PLHSRDWEIESTSSESKSSSSSKYRPTWRPKRESLN 584
GD+ D+KP P T+ P+ SR WE S + +S K PK
Sbjct: 877 GDEEDEKPLPATVVNDHVPSSSRQPI-SRGWEDLRRSPQRGASLHRKEPIPENPKSTGA- 934
Query: 585 IDSIFSKDKRKHCGYTQLSPFSEDSAKEFIPDEPSKPPSYDIKFGGPSPQYKRWGPARPG 644
D Y+ L+ ++D + D P P + PARP
Sbjct: 935 -------DTHPQGKYSSLASKAQDVQQSTDADTEGHSPKAQ-----PGSTDRHASPARPP 982
Query: 645 SHLLEQHPRLIQRMESGYESSERNSSSPV--SLDAALPESSNVYRDPSAKRSAGLVPSWR 702
+ +QHP + +RM G + ++ PV S P+S + R PS R L + R
Sbjct: 983 AARSQQHPSVPRRMTPG-RAPQQQPPPPVATSQHHPGPQSRDAGRSPSQPR-LSLTQAGR 1040
Query: 703 HIPKSHSSSILEVDS-TASMGGWTKSQPFSGEEISSKSELDELQEEVARRAQEQELRRKR 761
P S S D TAS G + ++ ++ D+ EV + R
Sbjct: 1041 PRPTSQGRSHSSSDPYTASSRGMLPT-ALQNQDEDAQGSYDDDSTEVEAQDVRAPAHAAR 1099
Query: 762 EKELEAA 768
KE A+
Sbjct: 1100 AKEAAAS 1106
>gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo
sapiens]
Length = 1905
Score = 41.2 bits (95), Expect = 0.009
Identities = 63/233 (27%), Positives = 100/233 (42%), Gaps = 24/233 (10%)
Query: 732 GEEISSKSELDELQEEVARRAQEQELRRKR----EKELEAAK-GFNPHPSRFMDLDELQN 786
GE ++ S + EL+ ++ + ++ Q RK+ + L A G + + R+ L L
Sbjct: 1074 GEVDATASSIPELERQIEKLSKRQLFFRKKLLHSSQMLRAVSLGQDRYRRRYWVLPYLAG 1133
Query: 787 QGRSDGFERSLQEAESVFEESLHLEQKGDCAAALALCNEAISKLRLALHGASCSTHSRAL 846
+G E +L E + +E+ L+ AA A N A+ +++ L G++ + S A
Sbjct: 1134 IF-VEGTEGNLVPEEVIKKETDSLK-----VAAHASLNPALFSMKMELAGSNTTASSPAR 1187
Query: 847 V---DKKLQISIRKARSLQD--RMQQQQSPQQPSQPSACLPTQAGTLSQPTSEQPIPLQV 901
+K + + R L+ R Q + PQ QP A L A QP + + LQ
Sbjct: 1188 ARGRPRKTKPGSMQPRHLKSPVRGQDSEQPQAQLQPEAQLHAPA----QPQPQLQLQLQS 1243
Query: 902 ---LLSQEAQ-LESGMDTEFGASSFFHSPASCHESHSSLSPESSAPQHSSPSR 950
L QE L G + S F S S +SHSSL S SSP +
Sbjct: 1244 HKGFLEQEGSPLSLGQSQHDLSQSAFLSWLSQTQSHSSLLSSSVLTPDSSPGK 1296
>gi|62177129 Nedd4 binding protein 3 [Homo sapiens]
Length = 544
Score = 40.8 bits (94), Expect = 0.011
Identities = 40/139 (28%), Positives = 66/139 (47%), Gaps = 7/139 (5%)
Query: 734 EISSKSELDELQEEVARRAQEQELRRKREKELEAAKGFNPHPSRFMDLDELQNQGRSDGF 793
E++ K+E E ++ +QE RR R KEL A +G P P L E R +
Sbjct: 307 EVTQKAERSERNLQLQLFMAQQEQRRLR-KELRAQQGLAPEPRAPGTLPEADPSARPEE- 364
Query: 794 ERSLQEAESVFEESLHLEQKGDCAAALALCNEAISKLRLALHGASCSTHSRALVDKKLQI 853
E + + E SL +Q + A LA I L+ L G+ ++ D +L +
Sbjct: 365 EARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQ---DAEL-V 420
Query: 854 SIRKA-RSLQDRMQQQQSP 871
+R+A RSLQ++ ++++P
Sbjct: 421 RLREAVRSLQEQAPREEAP 439
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 40.4 bits (93), Expect = 0.015
Identities = 51/211 (24%), Positives = 87/211 (41%), Gaps = 27/211 (12%)
Query: 733 EEISSKSELDELQEEVARRAQEQELRRKREKELEAAKGFNP-HPSRFMDL------DELQ 785
EE + EL QEE+ RR QE+E +R+ E+EL K R ++ +E +
Sbjct: 747 EERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEE 806
Query: 786 NQGRSDGF----ERSLQEAESVFEESLHLEQKGDCAAALALCNEAISKL---RLALHGAS 838
Q + + ER +E E +E L +Q+ + A EA +L RL + +
Sbjct: 807 RQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEA 866
Query: 839 CSTHSRALVDKKLQISIRKARSLQ----------DRMQQQQSPQQPSQ---PSACLPTQA 885
K+ ++ +++ + L R+QQQQ QQ +Q PS+ Q
Sbjct: 867 ARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQ 926
Query: 886 GTLSQPTSEQPIPLQVLLSQEAQLESGMDTE 916
+ S+ + L + E + E + E
Sbjct: 927 SNTTACQSQATLSLAEIQKLEEERERQLREE 957
Score = 35.4 bits (80), Expect = 0.47
Identities = 36/150 (24%), Positives = 69/150 (46%), Gaps = 6/150 (4%)
Query: 733 EEISSKSELD-ELQEEVARRAQEQE--LRR--KREKELEAAKGFNPHPSRF-MDLDELQN 786
EE + EL+ + Q+E+ R+ Q+Q+ LRR +++++ + A+ P S + +
Sbjct: 873 EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 932
Query: 787 QGRSDGFERSLQEAESVFEESLHLEQKGDCAAALALCNEAISKLRLALHGASCSTHSRAL 846
Q ++ +Q+ E E L EQ+ + + + + L G +
Sbjct: 933 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT 992
Query: 847 VDKKLQISIRKARSLQDRMQQQQSPQQPSQ 876
L+I +AR +Q + QQQQ QQP++
Sbjct: 993 TKSLLEIQQEEARQMQKQQQQQQQHQQPNR 1022
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 40.4 bits (93), Expect = 0.015
Identities = 51/211 (24%), Positives = 87/211 (41%), Gaps = 27/211 (12%)
Query: 733 EEISSKSELDELQEEVARRAQEQELRRKREKELEAAKGFNP-HPSRFMDL------DELQ 785
EE + EL QEE+ RR QE+E +R+ E+EL K R ++ +E +
Sbjct: 774 EERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEE 833
Query: 786 NQGRSDGF----ERSLQEAESVFEESLHLEQKGDCAAALALCNEAISKL---RLALHGAS 838
Q + + ER +E E +E L +Q+ + A EA +L RL + +
Sbjct: 834 RQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEA 893
Query: 839 CSTHSRALVDKKLQISIRKARSLQ----------DRMQQQQSPQQPSQ---PSACLPTQA 885
K+ ++ +++ + L R+QQQQ QQ +Q PS+ Q
Sbjct: 894 ARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQ 953
Query: 886 GTLSQPTSEQPIPLQVLLSQEAQLESGMDTE 916
+ S+ + L + E + E + E
Sbjct: 954 SNTTACQSQATLSLAEIQKLEEERERQLREE 984
Score = 35.4 bits (80), Expect = 0.47
Identities = 36/150 (24%), Positives = 69/150 (46%), Gaps = 6/150 (4%)
Query: 733 EEISSKSELD-ELQEEVARRAQEQE--LRR--KREKELEAAKGFNPHPSRF-MDLDELQN 786
EE + EL+ + Q+E+ R+ Q+Q+ LRR +++++ + A+ P S + +
Sbjct: 900 EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 959
Query: 787 QGRSDGFERSLQEAESVFEESLHLEQKGDCAAALALCNEAISKLRLALHGASCSTHSRAL 846
Q ++ +Q+ E E L EQ+ + + + + L G +
Sbjct: 960 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT 1019
Query: 847 VDKKLQISIRKARSLQDRMQQQQSPQQPSQ 876
L+I +AR +Q + QQQQ QQP++
Sbjct: 1020 TKSLLEIQQEEARQMQKQQQQQQQHQQPNR 1049
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 40.4 bits (93), Expect = 0.015
Identities = 51/211 (24%), Positives = 87/211 (41%), Gaps = 27/211 (12%)
Query: 733 EEISSKSELDELQEEVARRAQEQELRRKREKELEAAKGFNP-HPSRFMDL------DELQ 785
EE + EL QEE+ RR QE+E +R+ E+EL K R ++ +E +
Sbjct: 753 EERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEE 812
Query: 786 NQGRSDGF----ERSLQEAESVFEESLHLEQKGDCAAALALCNEAISKL---RLALHGAS 838
Q + + ER +E E +E L +Q+ + A EA +L RL + +
Sbjct: 813 RQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEA 872
Query: 839 CSTHSRALVDKKLQISIRKARSLQ----------DRMQQQQSPQQPSQ---PSACLPTQA 885
K+ ++ +++ + L R+QQQQ QQ +Q PS+ Q
Sbjct: 873 ARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQ 932
Query: 886 GTLSQPTSEQPIPLQVLLSQEAQLESGMDTE 916
+ S+ + L + E + E + E
Sbjct: 933 SNTTACQSQATLSLAEIQKLEEERERQLREE 963
Score = 35.4 bits (80), Expect = 0.47
Identities = 36/150 (24%), Positives = 69/150 (46%), Gaps = 6/150 (4%)
Query: 733 EEISSKSELD-ELQEEVARRAQEQE--LRR--KREKELEAAKGFNPHPSRF-MDLDELQN 786
EE + EL+ + Q+E+ R+ Q+Q+ LRR +++++ + A+ P S + +
Sbjct: 879 EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 938
Query: 787 QGRSDGFERSLQEAESVFEESLHLEQKGDCAAALALCNEAISKLRLALHGASCSTHSRAL 846
Q ++ +Q+ E E L EQ+ + + + + L G +
Sbjct: 939 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT 998
Query: 847 VDKKLQISIRKARSLQDRMQQQQSPQQPSQ 876
L+I +AR +Q + QQQQ QQP++
Sbjct: 999 TKSLLEIQQEEARQMQKQQQQQQQHQQPNR 1028
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 40.4 bits (93), Expect = 0.015
Identities = 51/211 (24%), Positives = 87/211 (41%), Gaps = 27/211 (12%)
Query: 733 EEISSKSELDELQEEVARRAQEQELRRKREKELEAAKGFNP-HPSRFMDL------DELQ 785
EE + EL QEE+ RR QE+E +R+ E+EL K R ++ +E +
Sbjct: 753 EERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEE 812
Query: 786 NQGRSDGF----ERSLQEAESVFEESLHLEQKGDCAAALALCNEAISKL---RLALHGAS 838
Q + + ER +E E +E L +Q+ + A EA +L RL + +
Sbjct: 813 RQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEA 872
Query: 839 CSTHSRALVDKKLQISIRKARSLQ----------DRMQQQQSPQQPSQ---PSACLPTQA 885
K+ ++ +++ + L R+QQQQ QQ +Q PS+ Q
Sbjct: 873 ARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQ 932
Query: 886 GTLSQPTSEQPIPLQVLLSQEAQLESGMDTE 916
+ S+ + L + E + E + E
Sbjct: 933 SNTTACQSQATLSLAEIQKLEEERERQLREE 963
Score = 35.4 bits (80), Expect = 0.47
Identities = 36/150 (24%), Positives = 69/150 (46%), Gaps = 6/150 (4%)
Query: 733 EEISSKSELD-ELQEEVARRAQEQE--LRR--KREKELEAAKGFNPHPSRF-MDLDELQN 786
EE + EL+ + Q+E+ R+ Q+Q+ LRR +++++ + A+ P S + +
Sbjct: 879 EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 938
Query: 787 QGRSDGFERSLQEAESVFEESLHLEQKGDCAAALALCNEAISKLRLALHGASCSTHSRAL 846
Q ++ +Q+ E E L EQ+ + + + + L G +
Sbjct: 939 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT 998
Query: 847 VDKKLQISIRKARSLQDRMQQQQSPQQPSQ 876
L+I +AR +Q + QQQQ QQP++
Sbjct: 999 TKSLLEIQQEEARQMQKQQQQQQQHQQPNR 1028
>gi|38570099 glutamine-rich 1 [Homo sapiens]
Length = 776
Score = 40.4 bits (93), Expect = 0.015
Identities = 41/127 (32%), Positives = 65/127 (51%), Gaps = 14/127 (11%)
Query: 781 LDELQNQGRSDGFERSLQEAESVFEESLHLEQKGDCAAALALCNEAISKLRLALHGASCS 840
LD L ++G +LQE + ++ +Q G+C + A S L LA +
Sbjct: 31 LDSLASKG-----PEALQEFQQTATTTMVYQQGGNCIYTDST-EVAGSLLELA---CPVT 81
Query: 841 THSRALVDKKLQISIRKARSLQDRMQQQQSPQQPSQPSACLPTQAGTLSQPTSEQPIPLQ 900
T + ++ QI +++ + +Q ++Q QQSPQ Q SA L Q T+ QPT EQPI +Q
Sbjct: 82 TSVQPQTQQEQQIQVQQPQQVQVQVQVQQSPQ---QVSAQLSPQL-TVHQPT-EQPIQVQ 136
Query: 901 VLLSQEA 907
V + +A
Sbjct: 137 VQIQGQA 143
>gi|38570097 glutamine-rich 1 [Homo sapiens]
Length = 776
Score = 40.4 bits (93), Expect = 0.015
Identities = 41/127 (32%), Positives = 65/127 (51%), Gaps = 14/127 (11%)
Query: 781 LDELQNQGRSDGFERSLQEAESVFEESLHLEQKGDCAAALALCNEAISKLRLALHGASCS 840
LD L ++G +LQE + ++ +Q G+C + A S L LA +
Sbjct: 31 LDSLASKG-----PEALQEFQQTATTTMVYQQGGNCIYTDST-EVAGSLLELA---CPVT 81
Query: 841 THSRALVDKKLQISIRKARSLQDRMQQQQSPQQPSQPSACLPTQAGTLSQPTSEQPIPLQ 900
T + ++ QI +++ + +Q ++Q QQSPQ Q SA L Q T+ QPT EQPI +Q
Sbjct: 82 TSVQPQTQQEQQIQVQQPQQVQVQVQVQQSPQ---QVSAQLSPQL-TVHQPT-EQPIQVQ 136
Query: 901 VLLSQEA 907
V + +A
Sbjct: 137 VQIQGQA 143
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 40.0 bits (92), Expect = 0.019
Identities = 85/412 (20%), Positives = 146/412 (35%), Gaps = 51/412 (12%)
Query: 388 SSDTRTDSSTESYPYKHSHHESVVSHFSSDSQ--------GTVIYNVENDSMSQSSRDTG 439
SSD+ +DSS+E P K+ + + ++ I N + S S SS +
Sbjct: 166 SSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSS 225
Query: 440 HLTDSECNQKHTSKKGSLIERKRSSGRVRRKGDEPQASGYHSEGETLKEKQAPRNASKPS 499
DSE +K + + +K+ + K A K S
Sbjct: 226 SSDDSE-EEKAAATPKKTVPKKQVVAKA-------------------PVKAATTPTRKSS 265
Query: 500 SSTNRLRDFKETVSNMIHNRP---SLASQTNVGSHCRGRGGDQPDKKPPRTLPLHSRDWE 556
SS + D +E + N+P S + + G P K + P+ S
Sbjct: 266 SSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESS--- 322
Query: 557 IESTSSESKSSSSSKYRPTWRPKRESLNIDSIFSKDKRKHCGYTQLSPFSEDSAKEFIPD 616
E +S ES SSS + +P + +K + + S SED P
Sbjct: 323 -EDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPA 381
Query: 617 EPSKPPSYDIKFGGPSPQYKRWGPARPGSHLLEQHPRLIQRMESGYESSERNSSSPVSLD 676
+K S SP K PA + +L+ R S E +SSS
Sbjct: 382 GTTKNSSNKPAVTTKSPAVK---PAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKT 438
Query: 677 AALPESSNVYRDPSAKRSAGLVPSWRHIPKSHSSSILEVDSTASMGGWTKSQPFSGEEIS 736
+ ++ P A A L + P+ S + DS++S EE +
Sbjct: 439 KKMVATTK----PKATAKAALSLPAKQAPQGSRDSSSDSDSSSSE---------EEEEKT 485
Query: 737 SKSELDELQEEVARRAQEQELRRKREKELEAAKGFNPHPSRFMDLDELQNQG 788
SKS + + ++VA A + ++ + E++ + S + ++L+ +G
Sbjct: 486 SKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKG 537
Score = 31.6 bits (70), Expect = 6.8
Identities = 53/236 (22%), Positives = 84/236 (35%), Gaps = 32/236 (13%)
Query: 469 RKGDEPQASGYHSEGETLKEKQAPRNASKPSSSTNRLRDFKETVSNMIHNRPSLASQTNV 528
+KG +PQA K +AP +K S S + E N +P + T
Sbjct: 147 QKGVKPQA----------KAAKAPPKKAKSSDSDSDSSSEDEPPKNQ---KPKITPVTV- 192
Query: 529 GSHCRGRGGDQPDKKPPRTLPLHSRDWEIESTSSESKSSS---SSKYRPTWRPKRESLNI 585
+ + KP R P + S+SS S SSS S + + PK+
Sbjct: 193 ------KAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKK 246
Query: 586 DSIFSKDKRKHCGYTQLSPFSEDSAKEFIPDEPSKP------PSYDIKFGGPSPQYKRWG 639
+ + T+ S SEDS+ + +E KP P + P K G
Sbjct: 247 QVVAKAPVKAATTPTRKSSSSEDSSSD-EEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLG 305
Query: 640 PARPGSHLLEQHPRLIQRMESGYESSERNSSSPVSLDAALPESSNVYRDPSAKRSA 695
P + +Q P ++ E + S+ +S S + P AK++A
Sbjct: 306 TQPPKKAVEKQQP--VESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAA 359
>gi|224586851 sorbin and SH3 domain containing 2 isoform 6 [Homo
sapiens]
Length = 824
Score = 39.7 bits (91), Expect = 0.025
Identities = 104/491 (21%), Positives = 186/491 (37%), Gaps = 82/491 (16%)
Query: 606 SEDSAKEFIPDEPSKPP-SYDIKFGGPSPQYKRWGPARPGS---------HLLEQHPRLI 655
+EDS + + E S SY K P P PA + + + R I
Sbjct: 4 NEDSRQTIVYSEESNTTMSYTQKITNPLPAASSTDPAPFANINTPVLQEDYRQDSQTRRI 63
Query: 656 QRMESGYESSERNSSSPVSLDAALPESSNVYRDPS-AKRSAGLVPSWRHIPKSHSSSILE 714
++ + + + SSSP+S P+ S PS KR L P+ +P++H++S+
Sbjct: 64 STLKLTH-NQDLGSSSPIST----PQFSKSVEVPSFLKRPRSLTPN--PVPETHTASLS- 115
Query: 715 VDSTASMGGWTKSQPFSGEEISSKSELDELQEEVARRAQEQELRRKREKELEAAKGFNPH 774
+ P SG+++ S +L EL E A+ +QE R+K AA
Sbjct: 116 ----------IQIAPLSGQDLESHKQLPELSPETAKIPLQQE----RQKSAVAAAS---- 157
Query: 775 PSRFMDLDELQNQGRSDGFERSLQEAESVFEESLHLEQKGDCAAALALCNEAISKLRLAL 834
S + ++ G S G + + F S + + A N +I +
Sbjct: 158 QSSDCRVSQITVNGNSGGAVSPMSYYQRPFSPSAY--------SLPASLNSSI----VMQ 205
Query: 835 HGASCST------HSRALVDKKLQISIRKARSLQD--RMQQQQSPQQPS---QPSACLPT 883
HG S + H+++L D SI RS ++ R+ ++P P + +PT
Sbjct: 206 HGTSLDSTDTYPQHAQSL-DGTTSSSIPLYRSSEEEKRVTVIKAPHYPGIGPVDESGIPT 264
Query: 884 QAGTLSQPTSE--QPIPLQVLLSQEAQLESGM-DTEFGASSFFHSPASCHESHSSLSPES 940
T + + + Q+ + + ++ M +T + ++ ++P +SH + ++
Sbjct: 265 AIRTTVDRPKDWYKTMFKQIHMVHKPDDDTDMYNTPYTYNAGLYNPPYSAQSHPAAKTQT 324
Query: 941 SAP---QHSSPSRSALKLLTS-VEVDNIEPSAFHRQGLPKAPGWTEKNSHHSWEPLDAPE 996
P HS S +A K +S V ++ P P P H W+P P+
Sbjct: 325 YRPLSKSHSDNSPNAFKDASSPVPPPHVPPPV-----PPLRPRDRSSTEKHDWDP---PD 376
Query: 997 GKLQGSRCDNSSCSKLPPQEGRGIAQEQLFQEKKDPANPSPVMPGIATSERGDEHSLGCS 1056
K+ + + S + G+ + Q ++ P P P P E G +
Sbjct: 377 RKVDTRKFRSEPRSIFEYEPGK----SSILQHERPP--PLPTTPTPVPREPGRKPLSSSR 430
Query: 1057 PSNSSAQPSLP 1067
+ PS P
Sbjct: 431 LGEVTGSPSPP 441
>gi|62122917 filaggrin family member 2 [Homo sapiens]
Length = 2391
Score = 39.7 bits (91), Expect = 0.025
Identities = 37/170 (21%), Positives = 63/170 (37%), Gaps = 8/170 (4%)
Query: 369 QSYSRTCYDSEDSGREPSISSDTRTDSSTESYPYKHSHHESVVSHFSSDSQGTVIYNVEN 428
Q+ SRT SG S+ + S + H+H ++ H S+S ++
Sbjct: 1790 QTGSRTT-GRRSSGHSEYSDSEGHSGFSQRPHSRGHTHGQAGSQHGESES---IVDERHG 1845
Query: 429 DSMSQSSRDTGHLTDSECNQKHTSKKGSLIERKRSSGRVRRKGDEPQASGYHSE-GETLK 487
+ Q+ +GH S+ +++ GS +R SG E + G H+ G T
Sbjct: 1846 TTHGQTGDTSGH---SQSGHGQSTQSGSSTTGRRRSGHSESSDSEVHSGGSHTHSGHTHS 1902
Query: 488 EKQAPRNASKPSSSTNRLRDFKETVSNMIHNRPSLASQTNVGSHCRGRGG 537
+ ++ S+ + +T H PS GS GR G
Sbjct: 1903 QARSQHGESESTVHKRHQTTHGQTGDTTEHGHPSHGQTIQTGSRTTGRRG 1952
>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
homolog 2 [Homo sapiens]
Length = 1210
Score = 39.7 bits (91), Expect = 0.025
Identities = 59/247 (23%), Positives = 90/247 (36%), Gaps = 28/247 (11%)
Query: 835 HGASCSTHSRALVDKKLQISIRKARSLQDRMQQQQSPQQPSQPSACLPTQAGTLSQPTSE 894
+ S THS + + S + +Q+P++P PS+ P A
Sbjct: 405 YDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKP--PSSSAPPSA------PQS 456
Query: 895 QPIPLQVLLSQEAQLESGMDTEFGASSFFHSPASCHESHSSLSPESSAPQHSSPSRSALK 954
P P+ S A+ ES D++ + S S +S E + L E+ AP+ P+ + +
Sbjct: 457 LPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPL--ETPAPEPEPPTTNKWQ 514
Query: 955 L---LTSVEVD--------NIEPSAFHRQGLPKAPGWTEKNSHHSWEP-----LDAPEGK 998
L LT V + EP H + + T + S +P AP
Sbjct: 515 LDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAP 574
Query: 999 LQGSRCDNSSCSKLPPQEGRGIAQEQLFQEKKDPANPSPVMPGIATSERGDEHSLGCSPS 1058
+ SC K P Q+ Q ++ K P S G TS +G E G P
Sbjct: 575 PEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKAS-ARAGSRTSLQG-EREPGLLPY 632
Query: 1059 NSSAQPS 1065
S Q S
Sbjct: 633 GSRDQTS 639
Score = 32.0 bits (71), Expect = 5.2
Identities = 57/236 (24%), Positives = 90/236 (38%), Gaps = 34/236 (14%)
Query: 377 DSEDSGREPSISSDTRTDSSTESYPYKHSHHESVVSHFSSDSQGTVIYNVENDSMSQSSR 436
DSE + +P SS + + P +H S S +SDS + + E++S S S
Sbjct: 436 DSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSS--SDSESESSSSDSE 493
Query: 437 DTGHL-TDSECNQKHTSKKGSL-------------IERKRSSGRVRR----KGDEPQA-S 477
+ L T + + T+ K L E RS+ RR KG A S
Sbjct: 494 ENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATS 553
Query: 478 GYHSEGE------TLKEKQAPRNASKP------SSSTNRLRDFKETVSNMIHNRPSLASQ 525
HSE + + K +AP A P S + ++TV +P AS
Sbjct: 554 QEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKAS- 612
Query: 526 TNVGSHCRGRGGDQPDKKPPRTLPLHSRDWEIESTSSESKSSSSSKYRPTWRPKRE 581
GS +G +P P + S+D T ++++S++ +P P E
Sbjct: 613 ARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSE 668
>gi|38261962 activating transcription factor 7 interacting protein
[Homo sapiens]
Length = 1270
Score = 39.3 bits (90), Expect = 0.033
Identities = 67/333 (20%), Positives = 122/333 (36%), Gaps = 64/333 (19%)
Query: 649 EQHPRLIQRMESGYESSERNSSSPVSLDAALPESSNVYRDPSAKRSAGLVPSWRHIPKSH 708
E +P L ++MES + S + SS S + A LV S
Sbjct: 462 ETNPDLEEKMESSFGSPSKQESSE-----------------SLPKEAFLVLS-------- 496
Query: 709 SSSILEVDSTASMGGWTKSQPFSGEEISSKSELDELQEEVARRAQEQELRRKREKELEAA 768
D G +S+ S E S +E++ +++ +EQ + E+ E
Sbjct: 497 -------DEEDISGEKDESEVISQNETCSPAEVESNEKDNKPEEEEQVIHEDDERPSEKN 549
Query: 769 KGFNPHPSRFMDLDELQNQGRSDGFERSLQEAESVFEESLHLEQKGD------------- 815
+ S+ D+D +Q++ R E E E + + KGD
Sbjct: 550 EFSRRKRSKSEDMDNVQSK------RRRYMEEEYEAEFQVKITAKGDINQKLQKVIQWLL 603
Query: 816 ----CAAALALCNEAISKLRLALHGASCS-THSRALVDKKLQISIRKARSLQDRMQQQQS 870
CA A+ ++ +++L+ + C+ H L + + +I+ R + ++
Sbjct: 604 EEKLCALQCAVFDKTLAELKTRVEKIECNKRHKTVLTELQAKIARLTKRFEAAKEDLKKR 663
Query: 871 PQQPSQPSACLPTQAG-TLSQPTSEQPIPLQVLLSQEAQLESGMDTEFGASSFFHSPASC 929
+ P P P G T++ S + + + LES + A F +P +
Sbjct: 664 HEHPPNP----PVSPGKTVNDVNSNNNMSYRNAGTVRQMLESKRNVSESAPPSFQTPVNT 719
Query: 930 HESHSSLSPE---SSAPQHSSPSRSALKLLTSV 959
S + ++P SS P+ +P S TSV
Sbjct: 720 VSSTNLVTPPAVVSSQPKLQTPVTSGSLTATSV 752
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 39.3 bits (90), Expect = 0.033
Identities = 78/354 (22%), Positives = 134/354 (37%), Gaps = 53/354 (14%)
Query: 723 GWTKSQPFSGEEISSKSELDELQ-EEVARRAQEQELRRKREKELEAAKGFNPHPSRFMDL 781
G + P S +S+ + +LQ ++VA + Q+Q+ + +++++ L
Sbjct: 132 GTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAA--------------L 177
Query: 782 DELQNQGRSDGFERSL----QEAESVFEESLHLEQKGDCAAALALCNEAISKLRLALHGA 837
+ Q Q + F+ Q+ ++V ++ L+Q+ L ++L
Sbjct: 178 QQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHL---------IKLHHQNQ 228
Query: 838 SCSTHSRALVDKKLQISIRKARSLQDRMQQQQSPQQPSQPSACLPTQAGTLSQPTSEQPI 897
+ + + Q+ +++ + Q + QQQQ +QP P Q + QP QP
Sbjct: 229 QQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQP----PIQQPPMQQP---QPP 281
Query: 898 PLQVLLSQEAQLESGMDTEFGASSFFHSPASCHESHSSLSPESSAPQHSSPSRSALKLLT 957
P Q L Q Q+ + P S L P+S + P S + L
Sbjct: 282 PSQALPQQLQQMHHTQHHQPPPQP--QQPPVAQNQPSQLPPQS----QTQPLVSQAQALP 335
Query: 958 SVEVDNIEPSAFHR-----QGLPKAPGWTEKNSHHSWEPLDAPEGKLQGSRCDNSSCSKL 1012
+ P F R Q P P ++ + + + A + G + SS L
Sbjct: 336 GQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQT--AVQTAQAAQMVAPGVQVSQSSLPML 393
Query: 1013 -PPQEGRGIAQEQLFQEKKDPANPSPVMPGIATSERGDEHSLGCSPSNSSAQPS 1065
P G+ Q Q Q P PSP PG +S+ S G +PS SS PS
Sbjct: 394 SSPSPGQ---QVQTPQSMPPPPQPSP-QPGQPSSQPNSNVSSGPAPSPSSFLPS 443
>gi|217035133 hypothetical protein LOC55765 isoform 2 [Homo sapiens]
Length = 578
Score = 39.3 bits (90), Expect = 0.033
Identities = 41/151 (27%), Positives = 60/151 (39%), Gaps = 21/151 (13%)
Query: 871 PQQPSQPSACLPTQAGTLSQPTS-EQPIPLQVLLSQEAQLESGMDTEFGASSFFHSPASC 929
P+ P+ PS LP Q QPT E P + + E+ +D + P
Sbjct: 201 PESPAPPSRPLPPQTLEGLQPTGPEAGSPERAPVQNSPWKETSLDHP------YEKPRKS 254
Query: 930 HESHSSLSPESSAPQHSSPSRSALKLLTSVEVDNIEPSAFHRQGLPKAPG-WTEKNSHHS 988
E S S ++ PQ PS S+L LL EP+++H + PG W + S +
Sbjct: 255 SEPWSESSSPATTPQ-DGPSASSLWLL--------EPASYHVVPIRGVPGQWQGRTSAPA 305
Query: 989 WEPLDAPEGKLQGSRCDNSSCSKLPPQEGRG 1019
+ G+ Q R D+ EGRG
Sbjct: 306 TPEIQGRRGQSQSLRVDSFRAG----PEGRG 332
>gi|217035131 hypothetical protein LOC55765 isoform 1 [Homo sapiens]
Length = 663
Score = 39.3 bits (90), Expect = 0.033
Identities = 41/151 (27%), Positives = 60/151 (39%), Gaps = 21/151 (13%)
Query: 871 PQQPSQPSACLPTQAGTLSQPTS-EQPIPLQVLLSQEAQLESGMDTEFGASSFFHSPASC 929
P+ P+ PS LP Q QPT E P + + E+ +D + P
Sbjct: 286 PESPAPPSRPLPPQTLEGLQPTGPEAGSPERAPVQNSPWKETSLDHP------YEKPRKS 339
Query: 930 HESHSSLSPESSAPQHSSPSRSALKLLTSVEVDNIEPSAFHRQGLPKAPG-WTEKNSHHS 988
E S S ++ PQ PS S+L LL EP+++H + PG W + S +
Sbjct: 340 SEPWSESSSPATTPQ-DGPSASSLWLL--------EPASYHVVPIRGVPGQWQGRTSAPA 390
Query: 989 WEPLDAPEGKLQGSRCDNSSCSKLPPQEGRG 1019
+ G+ Q R D+ EGRG
Sbjct: 391 TPEIQGRRGQSQSLRVDSFRAG----PEGRG 417
>gi|91208420 bassoon protein [Homo sapiens]
Length = 3926
Score = 38.9 bits (89), Expect = 0.043
Identities = 46/169 (27%), Positives = 75/169 (44%), Gaps = 30/169 (17%)
Query: 716 DSTASMGGWTKSQP-FSGEEISSKSELDELQEEVARRAQEQELRRKREK-ELEAAKGFNP 773
D+ G S+P F EE S QEE R+ QEQ L+ +RE+ ELE +
Sbjct: 2339 DAAPGGGSGALSRPGFEKEEAS--------QEERQRKQQEQLLQLERERVELEKLRQLRL 2390
Query: 774 HPSRFMDLDELQNQGRSDGF--ERSLQEAESVFEESLHLEQKGDCAAALALCNEAISKLR 831
+ ELQ + +R LQE +++ L +Q+ + A AL E +++ R
Sbjct: 2391 QEELERERVELQRHREEEQLLVQRELQELQTIKHHVLQ-QQQEERQAQFALQREQLAQQR 2449
Query: 832 LALHGASCSTHSRALVDKKLQISIRKARSLQDRMQQQQSPQQPSQPSAC 880
L L ++LQ + LQ ++++Q+ Q+ P+AC
Sbjct: 2450 LQLEQI-----------QQLQ------QQLQQQLEEQKQRQKAPFPAAC 2481
Score = 33.5 bits (75), Expect = 1.8
Identities = 50/209 (23%), Positives = 83/209 (39%), Gaps = 30/209 (14%)
Query: 867 QQQSPQQPSQPSACLPTQAGTLSQPTSEQPIPLQVLLSQEAQLESGMDTEFGASSFFHSP 926
+Q+ PQ QPS LP +A LS T P+P + S AS +P
Sbjct: 554 KQKGPQGLGQPSGPLPAKASPLS--TKASPLPSKA---------SPQAKPLRASEPSKTP 602
Query: 927 ASCHESHSSL----SPESSAPQHSSPSRSALKLLTSVEVDNIEPSAFHRQGLPKAPGWTE 982
+S E + + P P ++P+ + K+ + V EP+ + +P+AP E
Sbjct: 603 SSVQEKKTRVPTKAEPMPKPPPETTPTPATPKVKSGVR--RAEPATPVVKAVPEAPKGGE 660
Query: 983 K----NSHHSWEPLDAPEGKLQ-GSRCDNSSCSKLPPQEGRGIAQEQLFQ-EKKDPANPS 1036
+S + +P+ G D S S+ E G+ Q+++ Q + P
Sbjct: 661 AEDLVGKPYSQDASRSPQSLSDTGYSSDGISSSQ---SEITGVVQQEVEQLDSAGVTGPH 717
Query: 1037 PVMPG----IATSERGDEHSLGCSPSNSS 1061
P P + +S R + G +PS S
Sbjct: 718 PPSPSEIHKVGSSMRPLLQAQGLAPSERS 746
>gi|98961135 family with sequence similarity 48, member A isoform a
[Homo sapiens]
Length = 779
Score = 38.9 bits (89), Expect = 0.043
Identities = 41/137 (29%), Positives = 57/137 (41%), Gaps = 21/137 (15%)
Query: 860 SLQDRMQQ--QQSPQQPSQPSACLPTQAGTLSQ---PTSEQPIPLQVLLSQEAQLESGMD 914
+LQ + QQ Q +PQQP QP+ C P Q G TS++ Q L +Q+A +
Sbjct: 634 TLQQQQQQLSQFTPQQPQQPTTCSPQQPGEQGSEQGSTSQE----QALSAQQA----AVI 685
Query: 915 TEFGASSFFHSPASCHESHSSLS--PESSAPQHSSPSRSALKLLTSVEVDNIEPSAF--H 970
G SF S A+ S PE S PQ SA + + I+ F H
Sbjct: 686 NLTGVGSFMQSQAAVLSQLGSAENRPEQSLPQQRFQLSSAFQ----QQQQQIQQLRFLQH 741
Query: 971 RQGLPKAPGWTEKNSHH 987
+ + A T + HH
Sbjct: 742 QMAMAAAAAQTAQLHHH 758
>gi|13129104 coiled-coil domain containing 86 [Homo sapiens]
Length = 360
Score = 38.9 bits (89), Expect = 0.043
Identities = 66/319 (20%), Positives = 114/319 (35%), Gaps = 38/319 (11%)
Query: 458 IERKRSSGRVRRKGDEPQASGYHSEGETLKEKQAPRNASKPSSSTNRLRDFKETVSNMIH 517
+ R R G +R + E S + ++ + P +P S + V
Sbjct: 5 LRRSRRLGGLRPESPESLTSVSRTRRALVEFESNPEETREPGSPPS--------VQRAGL 56
Query: 518 NRPSLASQTNVGSHC--RGRGGDQPDKKPP--RTLPLHSRDWEIESTSSESKSSSSSKYR 573
P +T+ GS +G G + P +P P +D +ES + + S S
Sbjct: 57 GSPERPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQDLHLESPQRQPEYSPES--- 113
Query: 574 PTWRPK---------RESLNIDSIFSKDKRKHCGYTQLSPFSEDSAKEFIPDEPSKPPSY 624
P +PK ++ + S +++K +L+P + +P P P
Sbjct: 114 PRCQPKPSEEAPKCSQDQGVLASELAQNKE------ELTPGAPQHQLPPVPGSPEPYPGQ 167
Query: 625 DIKFGGPSPQYKRWGPARPGS----HLLEQHPRLIQRMESGYESSERNSSSPVSLDAALP 680
PS P PGS H + P + + G+ + +R SS + +
Sbjct: 168 QAPGPEPSQPLLELTPRAPGSPRGQHEPSKPPPAGETVTGGFGAKKRKGSSSQAPASKKL 227
Query: 681 ESSNVYRDPSAKRSAGLVPSWRHIPKSHSSSILEVDSTASMGGWTKSQPFSGEEISSKSE 740
+ P K +G V W+ K S +L+ + W + E +K
Sbjct: 228 NKEELPVIPKGKPKSGRV--WKDRSKKRFSQMLQDKPLRT--SWQRKMKERQERKLAKDF 283
Query: 741 LDELQEEVARRAQEQELRR 759
L+EE RR QE++ RR
Sbjct: 284 ARHLEEEKERRRQEKKQRR 302
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 38.5 bits (88), Expect = 0.056
Identities = 49/241 (20%), Positives = 73/241 (30%), Gaps = 15/241 (6%)
Query: 385 PSISSDTRTDSSTESYPYKHSHHESVVSHFSSDSQGTVIYNVENDSMSQSSRDTGHLTDS 444
PS+ SDT + E+ + + D + E SR +
Sbjct: 208 PSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKK-------EEKRRHSRSRSRSRRRRT 260
Query: 445 ECNQKHTSKKGSLIERKRSSGRVRRKGDEPQASGYHSEGETLKEKQAPRNASKPSSSTNR 504
+ +H + R S R RR+ P+ HS + + + K +
Sbjct: 261 PSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEK 320
Query: 505 LRDFKETVSNMIHNRPSLASQTNVGSHCRGRGGDQPDKKPPRTLPLHSRDWEIESTSSES 564
R S R AS+ R R G + KKP SR S
Sbjct: 321 KRSKTPPKSYSTARRSRSASRER--RRRRSRSGTRSPKKPRSPKRKLSRS---PSPRRHK 375
Query: 565 KSSSSSKYRPTWRPKRESLNIDSIFSKDKRKHCGYTQLSPFSEDSAKEFIPDEPSKPPSY 624
K K + R +RE SKDK K + S+ K+ D + Y
Sbjct: 376 KEKKKDKDKERSRDERERSTSKKKKSKDKEKD---RERKSESDKDVKQVTRDYDEEEQGY 432
Query: 625 D 625
D
Sbjct: 433 D 433
>gi|47578107 delangin isoform B [Homo sapiens]
Length = 2697
Score = 38.5 bits (88), Expect = 0.056
Identities = 49/223 (21%), Positives = 83/223 (37%), Gaps = 30/223 (13%)
Query: 384 EPSISSDTRTDSSTESYPYKHSHHESVVSHFSSDSQGTVIYNVENDSMSQSSRDTGHLTD 443
+P +S S + K + + V + S + T + + SR T
Sbjct: 605 DPELSKSEMKQSESRLAESKPNENRLVETKSSENKLETKVETQTEELKQNESRTT----- 659
Query: 444 SECNQKHTSKKGSLIERKRSSGRVR--RKGDEPQASGYH----SEGETLKEK-----QAP 492
EC Q ++ ++E K++ R+ + D Q +G S ET K+K + P
Sbjct: 660 -ECKQNEST----IVEPKQNENRLSDTKPNDNKQNNGRSETTKSRPETPKQKGESRPETP 714
Query: 493 RNASK--PSSSTNRLRDFKETVSNMIHNRPSLASQTNVGS-------HCRGRGGDQPDKK 543
+ S P + + ET +RP Q N G H R +P +
Sbjct: 715 KQKSDGHPETPKQKGDGRPETPKQKGESRPETPKQKNEGRPETPKHRHDNRRDSGKPSTE 774
Query: 544 PPRTLPLHSRDWEIESTSSESKSSSSSKYRPTWRPKRESLNID 586
+ H +D + +S +S+ + + K RP R ESL D
Sbjct: 775 KKPEVSKHKQDTKSDSPRLKSERAEALKQRPDGRSVSESLRRD 817
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.128 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 74,046,008
Number of Sequences: 37866
Number of extensions: 3855294
Number of successful extensions: 14035
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 48
Number of HSP's successfully gapped in prelim test: 251
Number of HSP's that attempted gapping in prelim test: 12970
Number of HSP's gapped (non-prelim): 1243
length of query: 1684
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1568
effective length of database: 13,855,062
effective search space: 21724737216
effective search space used: 21724737216
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.