Guide to the Human Genome
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Search of human proteins with 122939165

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|122939165 NudC domain containing 3 [Homo sapiens]
         (361 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|122939165 NudC domain containing 3 [Homo sapiens]                  727   0.0  
gi|5729953 nuclear distribution gene C homolog [Homo sapiens]         135   7e-32
gi|12711676 UPF3 regulator of nonsense transcripts homolog A iso...    39   0.006
gi|18375525 UPF3 regulator of nonsense transcripts homolog A iso...    39   0.006
gi|205277396 dynactin 1 isoform 4 [Homo sapiens]                       39   0.007
gi|205277392 dynactin 1 isoform 3 [Homo sapiens]                       39   0.007
gi|118600967 shroom family member 4 [Homo sapiens]                     38   0.016
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)...    37   0.021
gi|41872673 NIMA-related kinase 1 [Homo sapiens]                       37   0.027
gi|74272280 aryl hydrocarbon receptor interacting protein-like 1...    37   0.027
gi|74272278 aryl hydrocarbon receptor interacting protein-like 1...    37   0.027
gi|74272276 aryl hydrocarbon receptor interacting protein-like 1...    37   0.027
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ...    37   0.036
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ...    37   0.036
gi|154354979 myosin X [Homo sapiens]                                   37   0.036
gi|189571679 NudC domain containing 1 isoform 2 [Homo sapiens]         37   0.036
gi|189571677 NudC domain containing 1 isoform 1 [Homo sapiens]         37   0.036
gi|21687129 NudC domain containing 2 [Homo sapiens]                    37   0.036
gi|13259508 dynactin 1 isoform 2 [Homo sapiens]                        36   0.047
gi|13259510 dynactin 1 isoform 1 [Homo sapiens]                        36   0.047
gi|169207217 PREDICTED: zinc finger homeobox 2 [Homo sapiens]          36   0.061
gi|169207592 PREDICTED: zinc finger homeobox 2 [Homo sapiens]          36   0.061
gi|169207014 PREDICTED: zinc finger homeobox 2 [Homo sapiens]          36   0.061
gi|30795231 brain abundant, membrane attached signal protein 1 [...    35   0.080
gi|92087055 PERQ amino acid rich, with GYF domain 1 [Homo sapiens]     35   0.14 
gi|118601081 heterogeneous nuclear ribonucleoprotein U-like 2 [H...    35   0.14 
gi|126722969 centromere protein T [Homo sapiens]                       34   0.18 
gi|21264355 SWI/SNF-related matrix-associated actin-dependent re...    34   0.18 
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    34   0.23 
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...    34   0.23 

>gi|122939165 NudC domain containing 3 [Homo sapiens]
          Length = 361

 Score =  727 bits (1876), Expect = 0.0
 Identities = 361/361 (100%), Positives = 361/361 (100%)

Query: 1   METGAAELYDQALLGILQHVGNVQDFLRVLFGFLYRKTDFYRLLRHPSDRMGFPPGAAQA 60
           METGAAELYDQALLGILQHVGNVQDFLRVLFGFLYRKTDFYRLLRHPSDRMGFPPGAAQA
Sbjct: 1   METGAAELYDQALLGILQHVGNVQDFLRVLFGFLYRKTDFYRLLRHPSDRMGFPPGAAQA 60

Query: 61  LVLQVFKTFDHMARQDDEKRRQELEEKIRRKEEEEAKTVSAAAAEKEPVPVPVQEIEIDS 120
           LVLQVFKTFDHMARQDDEKRRQELEEKIRRKEEEEAKTVSAAAAEKEPVPVPVQEIEIDS
Sbjct: 61  LVLQVFKTFDHMARQDDEKRRQELEEKIRRKEEEEAKTVSAAAAEKEPVPVPVQEIEIDS 120

Query: 121 TTELDGHQEVEKVQPPGPVKEMAHGSQEAEAPGAVAGAAEVPREPPILPRIQEQFQKNPD 180
           TTELDGHQEVEKVQPPGPVKEMAHGSQEAEAPGAVAGAAEVPREPPILPRIQEQFQKNPD
Sbjct: 121 TTELDGHQEVEKVQPPGPVKEMAHGSQEAEAPGAVAGAAEVPREPPILPRIQEQFQKNPD 180

Query: 181 SYNGAVRENYTWSQDYTDLEVRVPVPKHVVKGKQVSVALSSSSIRVAMLEENGERVLMEG 240
           SYNGAVRENYTWSQDYTDLEVRVPVPKHVVKGKQVSVALSSSSIRVAMLEENGERVLMEG
Sbjct: 181 SYNGAVRENYTWSQDYTDLEVRVPVPKHVVKGKQVSVALSSSSIRVAMLEENGERVLMEG 240

Query: 241 KLTHKINTESSLWSLEPGKCVLVNLSKVGEYWWNAILEGEEPIDIDKINKERSMATVDEE 300
           KLTHKINTESSLWSLEPGKCVLVNLSKVGEYWWNAILEGEEPIDIDKINKERSMATVDEE
Sbjct: 241 KLTHKINTESSLWSLEPGKCVLVNLSKVGEYWWNAILEGEEPIDIDKINKERSMATVDEE 300

Query: 301 EQAVLDRLTFDYHQKLQGKPQSHELKVHEMLKKGWDAEGSPFRGQRFDPAMFNISPGAVQ 360
           EQAVLDRLTFDYHQKLQGKPQSHELKVHEMLKKGWDAEGSPFRGQRFDPAMFNISPGAVQ
Sbjct: 301 EQAVLDRLTFDYHQKLQGKPQSHELKVHEMLKKGWDAEGSPFRGQRFDPAMFNISPGAVQ 360

Query: 361 F 361
           F
Sbjct: 361 F 361


>gi|5729953 nuclear distribution gene C homolog [Homo sapiens]
          Length = 331

 Score =  135 bits (339), Expect = 7e-32
 Identities = 94/334 (28%), Positives = 166/334 (49%), Gaps = 27/334 (8%)

Query: 7   ELYDQALLGILQ-HVGNVQDFLRVLFGFLYRKTDFYRLLRHPSDRMGFPPGAAQALVLQV 65
           E +D  LL + Q H G VQ+ +   F FL RKTDF+         +G   G A+ L+ Q 
Sbjct: 8   ERFDGMLLAMAQQHEGGVQELVNTFFSFLRRKTDFF---------IGGEEGMAEKLITQT 58

Query: 66  FKTFDHMARQDDEKRRQELEEKIRRKEEEEAKTVSAAAAEKEPVPVPVQEIEIDSTTELD 125
           F   + +A++   ++R   E + R K E  A+    A +E           +I   T+  
Sbjct: 59  FSHHNQLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGP-------QIKELTD-- 109

Query: 126 GHQEVEKVQPPGPVKEMAHGSQEAEAPGAVAGAAEVPREPPILPRIQEQFQKNPDSYNGA 185
             +E E++Q     K+ A   +     G++    +   E       +++ +  P+  NGA
Sbjct: 110 --EEAERLQLEIDQKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDKGKLKPNLGNGA 167

Query: 186 VRENYTWSQDYTDLEVRVPVPKHV-VKGKQVSVALSSSSIRVAMLEENGERVLMEGKLTH 244
              NY W+Q  ++L++ VP   +  +KGK + V +    +RV +    G+  +++G+L +
Sbjct: 168 DLPNYRWTQTLSELDLAVPFCVNFRLKGKDMVVDIQRRHLRVGL---KGQPAIIDGELYN 224

Query: 245 KINTESSLWSLEPGKCVLVNLSKVGEY-WWNAILEGEEPIDIDKINKERS-MATVDEEEQ 302
           ++  E S W +E GK V V+L K+ +  WW+ ++  +  I+  KIN E S ++ +D E +
Sbjct: 225 EVKVEESSWLIEDGKVVTVHLEKINKMEWWSRLVSSDPEINTKKINPENSKLSDLDSETR 284

Query: 303 AVLDRLTFDYHQKLQGKPQSHELKVHEMLKKGWD 336
           ++++++ +D  QK  G P S E K  E+LKK  D
Sbjct: 285 SMVEKMMYDQRQKSMGLPTSDEQKKQEILKKFMD 318


>gi|12711676 UPF3 regulator of nonsense transcripts homolog A
           isoform hUpf3p [Homo sapiens]
          Length = 476

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 32/99 (32%), Positives = 48/99 (48%), Gaps = 12/99 (12%)

Query: 74  RQDDEKRRQELEEKIRRKEEEEAKTVSAAAAEKEPVPVPVQEIEIDSTTELDGHQE--VE 131
           R++ EK+R   EEK RR+EEE  K       +K    +  +E+ I    + +  +E   E
Sbjct: 241 RRELEKKRLREEEKRRRREEERCKKKETDKQKK----IAEKEVRIKLLKKPEKGEEPTTE 296

Query: 132 KVQPPGPVKEMAHGSQEAEAPGAVA------GAAEVPRE 164
           K +  G   +   G QE+ APGAV       G+ E P+E
Sbjct: 297 KPKERGEEIDTGGGKQESCAPGAVVKARPMEGSLEEPQE 335


>gi|18375525 UPF3 regulator of nonsense transcripts homolog A
           isoform hUpf3pdelta [Homo sapiens]
          Length = 443

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 32/99 (32%), Positives = 48/99 (48%), Gaps = 12/99 (12%)

Query: 74  RQDDEKRRQELEEKIRRKEEEEAKTVSAAAAEKEPVPVPVQEIEIDSTTELDGHQE--VE 131
           R++ EK+R   EEK RR+EEE  K       +K    +  +E+ I    + +  +E   E
Sbjct: 208 RRELEKKRLREEEKRRRREEERCKKKETDKQKK----IAEKEVRIKLLKKPEKGEEPTTE 263

Query: 132 KVQPPGPVKEMAHGSQEAEAPGAVA------GAAEVPRE 164
           K +  G   +   G QE+ APGAV       G+ E P+E
Sbjct: 264 KPKERGEEIDTGGGKQESCAPGAVVKARPMEGSLEEPQE 302


>gi|205277396 dynactin 1 isoform 4 [Homo sapiens]
          Length = 1139

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 30/117 (25%), Positives = 55/117 (47%), Gaps = 14/117 (11%)

Query: 67  KTFDHMARQDDEK------RRQELEEKIRRKEEEEAKTVSAAAAEKEPVPVPVQEIEIDS 120
           K  D  A+  DE+      R +E +  +R+KE+E  +T+ A  A+ + +    ++ E+  
Sbjct: 844 KKLDSAAKDADERIEKVQTRLEETQALLRKKEKEFEETMDALQADIDQLEA--EKAELKQ 901

Query: 121 TTELDGHQEVEKVQPPGP------VKEMAHGSQEAEAPGAVAGAAEVPREPPILPRI 171
                  + +E ++ P P      V  +A G+   +APG+V G   V   P +L +I
Sbjct: 902 RLNSQSKRTIEGLRGPPPSGIATLVSGIAGGAIPGQAPGSVPGPGLVKDSPLLLQQI 958


>gi|205277392 dynactin 1 isoform 3 [Homo sapiens]
          Length = 1253

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 30/117 (25%), Positives = 55/117 (47%), Gaps = 14/117 (11%)

Query: 67   KTFDHMARQDDEK------RRQELEEKIRRKEEEEAKTVSAAAAEKEPVPVPVQEIEIDS 120
            K  D  A+  DE+      R +E +  +R+KE+E  +T+ A  A+ + +    ++ E+  
Sbjct: 958  KKLDSAAKDADERIEKVQTRLEETQALLRKKEKEFEETMDALQADIDQLEA--EKAELKQ 1015

Query: 121  TTELDGHQEVEKVQPPGP------VKEMAHGSQEAEAPGAVAGAAEVPREPPILPRI 171
                   + +E ++ P P      V  +A G+   +APG+V G   V   P +L +I
Sbjct: 1016 RLNSQSKRTIEGLRGPPPSGIATLVSGIAGGAIPGQAPGSVPGPGLVKDSPLLLQQI 1072


>gi|118600967 shroom family member 4 [Homo sapiens]
          Length = 1493

 Score = 37.7 bits (86), Expect = 0.016
 Identities = 31/114 (27%), Positives = 49/114 (42%), Gaps = 3/114 (2%)

Query: 74   RQDDEKRRQELEEKIRRKEEEEAKTVSAAAAEKEPVPVPVQEIEIDSTTELDGHQEVEKV 133
            +Q  +K+++E EE+   +EEEE +    A  E+E +P      E   +  L+  + +E+ 
Sbjct: 1124 QQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEELPPQYFSSETSGSCALNPEEVLEQP 1183

Query: 134  QPP--GPVKEMAHGSQEAEAPGAVAGAAEVPREPPILPRIQEQ-FQKNPDSYNG 184
            QP   G ++    GSQ   A             PPI   +  Q  Q  P  Y G
Sbjct: 1184 QPLSFGHLEGSRQGSQSVPAEQESFALHSSDFLPPIRGHLGSQPEQAQPPCYYG 1237


>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
            [Homo sapiens]
          Length = 2073

 Score = 37.4 bits (85), Expect = 0.021
 Identities = 34/127 (26%), Positives = 53/127 (41%), Gaps = 11/127 (8%)

Query: 73   ARQDDEKRRQELEEKIRRKEEEEAKT-----VSAAAAEKEPVP-VPVQEIEIDSTTELD- 125
            AR DD +  +E +E+    E+ +A       + +A  EKE +P    +E+  +  T LD 
Sbjct: 1403 ARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQETFLDL 1462

Query: 126  ----GHQEVEKVQPPGPVKEMAHGSQEAEAPGAVAGAAEVPREPPILPRIQEQFQKNPDS 181
                GH   E +   G     +  S+  E  G      E   EPP   + Q+Q QKN   
Sbjct: 1463 NVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVPESDEEPPPGEQAQKQDQKNSKE 1522

Query: 182  YNGAVRE 188
             +   +E
Sbjct: 1523 VDTEFKE 1529



 Score = 32.3 bits (72), Expect = 0.68
 Identities = 27/107 (25%), Positives = 45/107 (42%), Gaps = 10/107 (9%)

Query: 67   KTFDHMARQDDEKRRQELEEKIRRKEEEEAKTVSAAAAEKEPVPVPVQE-------IEID 119
            K  D + + ++E+  +E EE+   +EEE  +       EK+P     QE        E +
Sbjct: 1342 KPEDDLIKPEEEEEEEE-EEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKE 1400

Query: 120  STTELDGHQEVEK--VQPPGPVKEMAHGSQEAEAPGAVAGAAEVPRE 164
             +  LD H+E E+   +P       A    ++    A     E+PRE
Sbjct: 1401 DSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRE 1447


>gi|41872673 NIMA-related kinase 1 [Homo sapiens]
          Length = 1258

 Score = 37.0 bits (84), Expect = 0.027
 Identities = 32/123 (26%), Positives = 59/123 (47%), Gaps = 13/123 (10%)

Query: 70  DHMARQDDEKRRQELEEKIR------RKEEEEAKTVSAAAAEKE---PVPVPVQEIEID- 119
           +++  Q+DEK +Q L +          KE E+ K+VS+   + E    + +P+ E+ +D 
Sbjct: 718 ENLKAQEDEKGKQNLSDTFEINVHEDAKEHEKEKSVSSDRKKWEAGGQLVIPLDELTLDT 777

Query: 120 --STTELDGHQEVEKVQPPGPVKEMAHGSQEAEAPGAVAGAAEVPREPPILPRIQEQFQK 177
             STTE     EV K+ P G  +  A G    ++   + G AE+  +  +L     + + 
Sbjct: 778 SFSTTERHTVGEVIKLGPNGSPRR-AWGKSPTDSVLKILGEAELQLQTELLENTTIRSEI 836

Query: 178 NPD 180
           +P+
Sbjct: 837 SPE 839


>gi|74272280 aryl hydrocarbon receptor interacting protein-like 1
           isoform 3 [Homo sapiens]
          Length = 324

 Score = 37.0 bits (84), Expect = 0.027
 Identities = 32/139 (23%), Positives = 58/139 (41%), Gaps = 11/139 (7%)

Query: 34  LYRKTDFYRLLRHPSDRMGFPPGAAQALVLQV---FKTFDHMARQDDEKRRQELEEKIRR 90
           L +K ++Y +L H SD +   PG  +A  ++     + ++    + D ++  ELE  +++
Sbjct: 180 LLKKEEYYEVLEHTSDILRHHPGIVKAYYVRARAHAEVWNEAEAKADLQKVLELEPSMQK 239

Query: 91  KEEEEAKTVSAAAAEKEPVPVPVQEIEIDSTTELDGHQEVEKVQPPGPVKEMAHGSQEAE 150
               E + +    AEK+      +E  +     L         +P  P +  A  S E  
Sbjct: 240 AVRRELRLLENRMAEKQ------EEERLRCRNMLSQGATQPPAEP--PTEPPAQSSTEPP 291

Query: 151 APGAVAGAAEVPREPPILP 169
           A    A +AE+   PP  P
Sbjct: 292 AEPPTAPSAELSAGPPAEP 310


>gi|74272278 aryl hydrocarbon receptor interacting protein-like 1
           isoform 2 [Homo sapiens]
          Length = 321

 Score = 37.0 bits (84), Expect = 0.027
 Identities = 32/139 (23%), Positives = 58/139 (41%), Gaps = 11/139 (7%)

Query: 34  LYRKTDFYRLLRHPSDRMGFPPGAAQALVLQV---FKTFDHMARQDDEKRRQELEEKIRR 90
           L +K ++Y +L H SD +   PG  +A  ++     + ++    + D ++  ELE  +++
Sbjct: 177 LLKKEEYYEVLEHTSDILRHHPGIVKAYYVRARAHAEVWNEAEAKADLQKVLELEPSMQK 236

Query: 91  KEEEEAKTVSAAAAEKEPVPVPVQEIEIDSTTELDGHQEVEKVQPPGPVKEMAHGSQEAE 150
               E + +    AEK+      +E  +     L         +P  P +  A  S E  
Sbjct: 237 AVRRELRLLENRMAEKQ------EEERLRCRNMLSQGATQPPAEP--PTEPPAQSSTEPP 288

Query: 151 APGAVAGAAEVPREPPILP 169
           A    A +AE+   PP  P
Sbjct: 289 AEPPTAPSAELSAGPPAEP 307


>gi|74272276 aryl hydrocarbon receptor interacting protein-like 1
           isoform 1 [Homo sapiens]
          Length = 384

 Score = 37.0 bits (84), Expect = 0.027
 Identities = 32/139 (23%), Positives = 58/139 (41%), Gaps = 11/139 (7%)

Query: 34  LYRKTDFYRLLRHPSDRMGFPPGAAQALVLQV---FKTFDHMARQDDEKRRQELEEKIRR 90
           L +K ++Y +L H SD +   PG  +A  ++     + ++    + D ++  ELE  +++
Sbjct: 240 LLKKEEYYEVLEHTSDILRHHPGIVKAYYVRARAHAEVWNEAEAKADLQKVLELEPSMQK 299

Query: 91  KEEEEAKTVSAAAAEKEPVPVPVQEIEIDSTTELDGHQEVEKVQPPGPVKEMAHGSQEAE 150
               E + +    AEK+      +E  +     L         +P  P +  A  S E  
Sbjct: 300 AVRRELRLLENRMAEKQ------EEERLRCRNMLSQGATQPPAEP--PTEPPAQSSTEPP 351

Query: 151 APGAVAGAAEVPREPPILP 169
           A    A +AE+   PP  P
Sbjct: 352 AEPPTAPSAELSAGPPAEP 370


>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
           [Homo sapiens]
          Length = 916

 Score = 36.6 bits (83), Expect = 0.036
 Identities = 55/255 (21%), Positives = 96/255 (37%), Gaps = 27/255 (10%)

Query: 81  RQELEEKIRRKEEEEAKTVSAAAAEKEPVPVPVQEI-EIDSTTELDGHQEVEKVQPPGPV 139
           ++E +E    KEEE        AA+K PV     E+ E +   E +  QE E+ +  G  
Sbjct: 485 KEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAK 544

Query: 140 KEMA-------HGSQEAEAPGAVAGAAEVPREPPILPRIQEQFQKNPDSYNGAVRENYTW 192
            + A        GS E E      G  E   E       +E+  +          E    
Sbjct: 545 SDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVAD 604

Query: 193 SQDYTDLEVRVPVPKHVVKGKQVSVALSSSSIRVAMLEENGERVLMEGKLTHKINTESSL 252
           ++     + + PVPK  V+ K        S +  + +EE G+  + +  +  K  +    
Sbjct: 605 AKVEKPEKAKSPVPKSPVEEK------GKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPK 658

Query: 253 WSLEPGKCVLVNLSKVGEYWWNAILEGEEPIDIDKINKERSMATV------DEEEQAVLD 306
             +E      V+ S V E       + + P+    + + +S A V      +EEE+ V +
Sbjct: 659 SPVEEKGKSPVSKSPVEE-------KAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKE 711

Query: 307 RLTFDYHQKLQGKPQ 321
               +  +K + KP+
Sbjct: 712 APKEEKVEKKEEKPK 726



 Score = 30.0 bits (66), Expect = 3.4
 Identities = 60/277 (21%), Positives = 110/277 (39%), Gaps = 31/277 (11%)

Query: 73  ARQDDEKRRQELEEKIRRKEE----------EEAKTV--SAAAAEKEPVPVPVQEIEIDS 120
           A   +EK+ +E  E++  KEE          E+AK+    +   EK   PVP   +E   
Sbjct: 580 AEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKG 639

Query: 121 TTELDGHQEVEKVQ---PPGPVKEMAHGSQEAEAPGAVAGAAEVPREPPILPRIQ----- 172
            + +      EK +   P  PV+E    S  +++P      + VP+ P    + +     
Sbjct: 640 KSPVPKSPVEEKGKSPVPKSPVEEKGK-SPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGK 698

Query: 173 -EQFQKNPDSYNGAVRENYTWSQDY--TDLEVRVPVPKHVVKGKQVSVALSSSSIRVAML 229
            EQ ++       A +E     ++    D+  +      V +     V   + S++V + 
Sbjct: 699 GEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLE 758

Query: 230 EENGE--RVLMEGKLTHKINTESSLWSLEPGKCVLVNLSKVGEYWWNAILEGEEPIDIDK 287
           +E  E  + L + K   K   E    S E G       S+  +   N  +EG+E  ++++
Sbjct: 759 KETKEEGKPLQQEKEKEKAGGEGG--SEEEGSDKGAKGSRKEDIAVNGEVEGKE--EVEQ 814

Query: 288 INKERSMATVDEEEQAVLDRLTFDYHQKLQGKPQSHE 324
             KE+     +EE+  V + L      + +G  +S E
Sbjct: 815 ETKEKGSGR-EEEKGVVTNGLDLSPADEKKGGDKSEE 850


>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
           [Homo sapiens]
          Length = 540

 Score = 36.6 bits (83), Expect = 0.036
 Identities = 55/255 (21%), Positives = 96/255 (37%), Gaps = 27/255 (10%)

Query: 81  RQELEEKIRRKEEEEAKTVSAAAAEKEPVPVPVQEI-EIDSTTELDGHQEVEKVQPPGPV 139
           ++E +E    KEEE        AA+K PV     E+ E +   E +  QE E+ +  G  
Sbjct: 109 KEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAK 168

Query: 140 KEMA-------HGSQEAEAPGAVAGAAEVPREPPILPRIQEQFQKNPDSYNGAVRENYTW 192
            + A        GS E E      G  E   E       +E+  +          E    
Sbjct: 169 SDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVAD 228

Query: 193 SQDYTDLEVRVPVPKHVVKGKQVSVALSSSSIRVAMLEENGERVLMEGKLTHKINTESSL 252
           ++     + + PVPK  V+ K        S +  + +EE G+  + +  +  K  +    
Sbjct: 229 AKVEKPEKAKSPVPKSPVEEK------GKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPK 282

Query: 253 WSLEPGKCVLVNLSKVGEYWWNAILEGEEPIDIDKINKERSMATV------DEEEQAVLD 306
             +E      V+ S V E       + + P+    + + +S A V      +EEE+ V +
Sbjct: 283 SPVEEKGKSPVSKSPVEE-------KAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKE 335

Query: 307 RLTFDYHQKLQGKPQ 321
               +  +K + KP+
Sbjct: 336 APKEEKVEKKEEKPK 350



 Score = 30.0 bits (66), Expect = 3.4
 Identities = 60/277 (21%), Positives = 110/277 (39%), Gaps = 31/277 (11%)

Query: 73  ARQDDEKRRQELEEKIRRKEE----------EEAKTV--SAAAAEKEPVPVPVQEIEIDS 120
           A   +EK+ +E  E++  KEE          E+AK+    +   EK   PVP   +E   
Sbjct: 204 AEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKG 263

Query: 121 TTELDGHQEVEKVQ---PPGPVKEMAHGSQEAEAPGAVAGAAEVPREPPILPRIQ----- 172
            + +      EK +   P  PV+E    S  +++P      + VP+ P    + +     
Sbjct: 264 KSPVPKSPVEEKGKSPVPKSPVEEKGK-SPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGK 322

Query: 173 -EQFQKNPDSYNGAVRENYTWSQDY--TDLEVRVPVPKHVVKGKQVSVALSSSSIRVAML 229
            EQ ++       A +E     ++    D+  +      V +     V   + S++V + 
Sbjct: 323 GEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLE 382

Query: 230 EENGE--RVLMEGKLTHKINTESSLWSLEPGKCVLVNLSKVGEYWWNAILEGEEPIDIDK 287
           +E  E  + L + K   K   E    S E G       S+  +   N  +EG+E  ++++
Sbjct: 383 KETKEEGKPLQQEKEKEKAGGEGG--SEEEGSDKGAKGSRKEDIAVNGEVEGKE--EVEQ 438

Query: 288 INKERSMATVDEEEQAVLDRLTFDYHQKLQGKPQSHE 324
             KE+     +EE+  V + L      + +G  +S E
Sbjct: 439 ETKEKGSGR-EEEKGVVTNGLDLSPADEKKGGDKSEE 474


>gi|154354979 myosin X [Homo sapiens]
          Length = 2058

 Score = 36.6 bits (83), Expect = 0.036
 Identities = 31/107 (28%), Positives = 52/107 (48%), Gaps = 6/107 (5%)

Query: 74  RQDDEKRRQELEEKIRRKEEEEAKTVSAAAAE----KEPVPVPVQEIEI--DSTTELDGH 127
           R+ +EK++QE EEK +R+EEE  +      AE    +E      QE+E    S  E +  
Sbjct: 816 REQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQKEAELT 875

Query: 128 QEVEKVQPPGPVKEMAHGSQEAEAPGAVAGAAEVPREPPILPRIQEQ 174
           +E+EK +    V+E+    +E E    +    E+      L ++QE+
Sbjct: 876 RELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQER 922


>gi|189571679 NudC domain containing 1 isoform 2 [Homo sapiens]
          Length = 554

 Score = 36.6 bits (83), Expect = 0.036
 Identities = 23/93 (24%), Positives = 43/93 (46%), Gaps = 6/93 (6%)

Query: 190 YTWSQDYTDLEVRVPVPKHVVKGKQVSVALSSSSIRVAMLEENGERVLMEGKLTHKINTE 249
           Y W Q   DL V + +P+   K + + +      I + + +       +EGKL   I+ E
Sbjct: 249 YYWQQTEDDLTVTIRLPEDSTK-EDIQIQFLPDHINIVLKDHQ----FLEGKLYSSIDHE 303

Query: 250 SSLWSLEPGKCVLVNLSKVGE-YWWNAILEGEE 281
           SS W ++    + ++L K  E   W  ++ G++
Sbjct: 304 SSTWIIKESNSLEISLIKKNEGLTWPELVIGDK 336


>gi|189571677 NudC domain containing 1 isoform 1 [Homo sapiens]
          Length = 583

 Score = 36.6 bits (83), Expect = 0.036
 Identities = 23/93 (24%), Positives = 43/93 (46%), Gaps = 6/93 (6%)

Query: 190 YTWSQDYTDLEVRVPVPKHVVKGKQVSVALSSSSIRVAMLEENGERVLMEGKLTHKINTE 249
           Y W Q   DL V + +P+   K + + +      I + + +       +EGKL   I+ E
Sbjct: 278 YYWQQTEDDLTVTIRLPEDSTK-EDIQIQFLPDHINIVLKDHQ----FLEGKLYSSIDHE 332

Query: 250 SSLWSLEPGKCVLVNLSKVGE-YWWNAILEGEE 281
           SS W ++    + ++L K  E   W  ++ G++
Sbjct: 333 SSTWIIKESNSLEISLIKKNEGLTWPELVIGDK 365


>gi|21687129 NudC domain containing 2 [Homo sapiens]
          Length = 157

 Score = 36.6 bits (83), Expect = 0.036
 Identities = 29/108 (26%), Positives = 47/108 (43%), Gaps = 11/108 (10%)

Query: 183 NGAVRENYTWSQDYTDLE---VRVPVPKHVVKGKQVSVALSSSSIRVAMLEENGERVLME 239
           +G V     W Q Y  LE   + V VP    + + +   L S  + +++    G R +++
Sbjct: 9   SGVVPCGTPWGQWYQTLEEVFIEVQVPPGT-RAQDIQCGLQSRHVALSV----GGREILK 63

Query: 240 GKLTHKINTESSLWSLEPGKCVLVNLSKV---GEYWWNAILEGEEPID 284
           GKL      +   W+LE  K V + L+K        W ++LE E   D
Sbjct: 64  GKLFDSTIADEGTWTLEDRKMVRIVLTKTKRDAANCWTSLLESEYAAD 111


>gi|13259508 dynactin 1 isoform 2 [Homo sapiens]
          Length = 1144

 Score = 36.2 bits (82), Expect = 0.047
 Identities = 29/122 (23%), Positives = 54/122 (44%), Gaps = 19/122 (15%)

Query: 67  KTFDHMARQDDEK------RRQELEEKIRRKEEEEAKTVSAAAAEKEPVPVPVQEIEIDS 120
           K  D  A+  DE+      R +E +  +R+KE+E  +T+ A  A+ + +    ++ E+  
Sbjct: 844 KKLDSAAKDADERIEKVQTRLEETQALLRKKEKEFEETMDALQADIDQLEA--EKAELKQ 901

Query: 121 TTELDGHQEVEKVQPPGPV-----------KEMAHGSQEAEAPGAVAGAAEVPREPPILP 169
                  + +E ++ P P            +E   G+   +APG+V G   V   P +L 
Sbjct: 902 RLNSQSKRTIEGLRGPPPSGIATLVSGIAGEEQQRGAIPGQAPGSVPGPGLVKDSPLLLQ 961

Query: 170 RI 171
           +I
Sbjct: 962 QI 963


>gi|13259510 dynactin 1 isoform 1 [Homo sapiens]
          Length = 1278

 Score = 36.2 bits (82), Expect = 0.047
 Identities = 29/122 (23%), Positives = 54/122 (44%), Gaps = 19/122 (15%)

Query: 67   KTFDHMARQDDEK------RRQELEEKIRRKEEEEAKTVSAAAAEKEPVPVPVQEIEIDS 120
            K  D  A+  DE+      R +E +  +R+KE+E  +T+ A  A+ + +    ++ E+  
Sbjct: 978  KKLDSAAKDADERIEKVQTRLEETQALLRKKEKEFEETMDALQADIDQLEA--EKAELKQ 1035

Query: 121  TTELDGHQEVEKVQPPGPV-----------KEMAHGSQEAEAPGAVAGAAEVPREPPILP 169
                   + +E ++ P P            +E   G+   +APG+V G   V   P +L 
Sbjct: 1036 RLNSQSKRTIEGLRGPPPSGIATLVSGIAGEEQQRGAIPGQAPGSVPGPGLVKDSPLLLQ 1095

Query: 170  RI 171
            +I
Sbjct: 1096 QI 1097


>gi|169207217 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
          Length = 2790

 Score = 35.8 bits (81), Expect = 0.061
 Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 5/83 (6%)

Query: 61   LVLQVFKTFDH--MARQDDEKRRQELEEKIRRKEEEEAKTVSAAAAEKEPVPVPV--QEI 116
            LV  + K +D   +  +++E  R E EE++  +E EE + +   A  + P+P P   +E+
Sbjct: 1903 LVRHLKKCYDDQTLEEEEEEAERGEEEEEVEEEEVEEEQGLEPPAGPEGPLPEPPDGEEL 1962

Query: 117  EIDSTTELDGHQEVEKVQP-PGP 138
                 T+  G +  EK  P P P
Sbjct: 1963 SQAEATKAGGKEPEEKATPSPSP 1985



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 25/96 (26%), Positives = 40/96 (41%), Gaps = 21/96 (21%)

Query: 65   VFKTFDHMARQDDEKRRQELEEKIRRKEEEEAKTVSAAAAEKEPVPVPVQEIEIDSTTEL 124
            VF+   H+ +  D++  +E EE+  R EEEE                 V+E E++    L
Sbjct: 1900 VFELVRHLKKCYDDQTLEEEEEEAERGEEEE----------------EVEEEEVEEEQGL 1943

Query: 125  DGHQEVEKVQPPGPVKEMAHGSQEAEAPGAVAGAAE 160
            +         P GP+ E   G + ++A    AG  E
Sbjct: 1944 E-----PPAGPEGPLPEPPDGEELSQAEATKAGGKE 1974


>gi|169207592 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
          Length = 2706

 Score = 35.8 bits (81), Expect = 0.061
 Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 5/83 (6%)

Query: 61   LVLQVFKTFDH--MARQDDEKRRQELEEKIRRKEEEEAKTVSAAAAEKEPVPVPV--QEI 116
            LV  + K +D   +  +++E  R E EE++  +E EE + +   A  + P+P P   +E+
Sbjct: 1819 LVRHLKKCYDDQTLEEEEEEAERGEEEEEVEEEEVEEEQGLEPPAGPEGPLPEPPDGEEL 1878

Query: 117  EIDSTTELDGHQEVEKVQP-PGP 138
                 T+  G +  EK  P P P
Sbjct: 1879 SQAEATKAGGKEPEEKATPSPSP 1901



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 25/96 (26%), Positives = 40/96 (41%), Gaps = 21/96 (21%)

Query: 65   VFKTFDHMARQDDEKRRQELEEKIRRKEEEEAKTVSAAAAEKEPVPVPVQEIEIDSTTEL 124
            VF+   H+ +  D++  +E EE+  R EEEE                 V+E E++    L
Sbjct: 1816 VFELVRHLKKCYDDQTLEEEEEEAERGEEEE----------------EVEEEEVEEEQGL 1859

Query: 125  DGHQEVEKVQPPGPVKEMAHGSQEAEAPGAVAGAAE 160
            +         P GP+ E   G + ++A    AG  E
Sbjct: 1860 E-----PPAGPEGPLPEPPDGEELSQAEATKAGGKE 1890


>gi|169207014 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
          Length = 2706

 Score = 35.8 bits (81), Expect = 0.061
 Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 5/83 (6%)

Query: 61   LVLQVFKTFDH--MARQDDEKRRQELEEKIRRKEEEEAKTVSAAAAEKEPVPVPV--QEI 116
            LV  + K +D   +  +++E  R E EE++  +E EE + +   A  + P+P P   +E+
Sbjct: 1819 LVRHLKKCYDDQTLEEEEEEAERGEEEEEVEEEEVEEEQGLEPPAGPEGPLPEPPDGEEL 1878

Query: 117  EIDSTTELDGHQEVEKVQP-PGP 138
                 T+  G +  EK  P P P
Sbjct: 1879 SQAEATKAGGKEPEEKATPSPSP 1901



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 25/96 (26%), Positives = 40/96 (41%), Gaps = 21/96 (21%)

Query: 65   VFKTFDHMARQDDEKRRQELEEKIRRKEEEEAKTVSAAAAEKEPVPVPVQEIEIDSTTEL 124
            VF+   H+ +  D++  +E EE+  R EEEE                 V+E E++    L
Sbjct: 1816 VFELVRHLKKCYDDQTLEEEEEEAERGEEEE----------------EVEEEEVEEEQGL 1859

Query: 125  DGHQEVEKVQPPGPVKEMAHGSQEAEAPGAVAGAAE 160
            +         P GP+ E   G + ++A    AG  E
Sbjct: 1860 E-----PPAGPEGPLPEPPDGEELSQAEATKAGGKE 1890


>gi|30795231 brain abundant, membrane attached signal protein 1
           [Homo sapiens]
          Length = 227

 Score = 35.4 bits (80), Expect = 0.080
 Identities = 30/110 (27%), Positives = 42/110 (38%), Gaps = 12/110 (10%)

Query: 70  DHMARQDDEKRRQELEEKIRRKEEEEAKTVSAAAAEKEPVPVPVQEIEIDSTTELDGHQE 129
           D  A++ D+K      E+    +E E +  +  A  KE    P Q+ E     E +G ++
Sbjct: 16  DEKAKEKDKKAEGAATEEEGTPKESEPQAAAEPAEAKEGKEKPDQDAE-GKAEEKEGEKD 74

Query: 130 VEKVQPPGPVKEMAHGSQEAEAPGAVAGAAEVPREPPILPRIQEQFQKNP 179
               +   P  E          P    GAAE   EPP  P  QEQ    P
Sbjct: 75  AAAAKEEAPKAE----------PEKTEGAAEAKAEPPKAPE-QEQAAPGP 113


>gi|92087055 PERQ amino acid rich, with GYF domain 1 [Homo sapiens]
          Length = 1035

 Score = 34.7 bits (78), Expect = 0.14
 Identities = 22/79 (27%), Positives = 39/79 (49%), Gaps = 16/79 (20%)

Query: 74  RQDDEKRRQELEEKIRRKEEEEAKTVSAAAAEKEPVPVP--------------VQEIEID 119
           +Q+++KRRQE EE  RRK   + + +     +++ VPVP               Q + + 
Sbjct: 713 QQEEQKRRQEEEELFRRKHVRQQELLLKLLQQQQAVPVPPAPSSPPPLWAGLAKQGLSMK 772

Query: 120 STTE--LDGHQEVEKVQPP 136
           +  E  L+G +++ K  PP
Sbjct: 773 TLLELQLEGERQLHKQPPP 791


>gi|118601081 heterogeneous nuclear ribonucleoprotein U-like 2 [Homo
           sapiens]
          Length = 747

 Score = 34.7 bits (78), Expect = 0.14
 Identities = 25/96 (26%), Positives = 43/96 (44%), Gaps = 8/96 (8%)

Query: 75  QDDEKRRQELEEKIRRKEEEEAKTVSAAAAEKEPVPVPVQEIEIDSTTELDGHQE-VEKV 133
           ++DE+  +E EE +   E+EE     A     +P P P +   +++  E D  ++  E  
Sbjct: 76  EEDEEEEEEDEEALLEDEDEEPPPAQALGQAAQPPPEPPEAAAMEAAAEPDASEKPAEAT 135

Query: 134 QPPGPV---KEMAHGSQEAEAPGAVAG----AAEVP 162
              G V   +E   G +E + P   +G     +EVP
Sbjct: 136 AGSGGVNGGEEQGLGKREEDEPEERSGDETPGSEVP 171


>gi|126722969 centromere protein T [Homo sapiens]
          Length = 561

 Score = 34.3 bits (77), Expect = 0.18
 Identities = 28/98 (28%), Positives = 43/98 (43%), Gaps = 15/98 (15%)

Query: 60  ALVLQVFKTFDHMARQDDEKRRQELEEKIRRKEEEEAKTVSAAAAEKEPVPVPVQEIEID 119
           A  L    T   ++ +D+ +   +  E+  +K EEE  +VS   A     P  V+E E  
Sbjct: 305 AFALGFLSTSSGVSGEDEVEPLHDGVEEAEKKMEEEGVSVSEMEATGAQGPSRVEEAE-- 362

Query: 120 STTELDGHQEVEKVQPPGPVKEMAHGSQEAEAPGAVAG 157
                 GH EV +        E + G+ EA+ PGA +G
Sbjct: 363 ------GHTEVTEA-------EGSQGTAEADGPGASSG 387


>gi|21264355 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin e1 [Homo sapiens]
          Length = 411

 Score = 34.3 bits (77), Expect = 0.18
 Identities = 29/112 (25%), Positives = 46/112 (41%), Gaps = 13/112 (11%)

Query: 70  DHMARQDDEKRRQELEEKIRRK------EEEEAKTVSAAAAEKEPVPVPVQEIEIDSTTE 123
           +  AR+  E+R +E  E+  R       EEE+A        + E +P+  +E  ++ TTE
Sbjct: 293 EEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTE 352

Query: 124 LDGHQE------VEKVQPPGPVKEMAHGSQEAEAPGAVAGAAEVPREPPILP 169
              + E       +K      V  MA         G+ + +A V  EPP  P
Sbjct: 353 SQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV-EEPPTDP 403


>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
            sapiens]
          Length = 1130

 Score = 33.9 bits (76), Expect = 0.23
 Identities = 33/146 (22%), Positives = 62/146 (42%), Gaps = 15/146 (10%)

Query: 52   GFPPGAAQALVLQVFKTFDHMARQDDEKRRQELEEK-----IRRKEEEEAKTVSAAAAEK 106
            G PP   + L +    + D    +++E+  +E EE+        +EE+E +       E+
Sbjct: 869  GGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEE 928

Query: 107  EPVPVPVQEI--EIDSTTELDGHQEVEKVQPPGPVKEMAHGSQEAEAPGAVAGAAEVPRE 164
            E      +E   E++   E +  +E E+++    V+++  G+   E      GA   P  
Sbjct: 929  EEFEEEFEEEEGELEEEEEEEDEEEEEELE---EVEDLEFGTAGGEVE---EGAPPPPTL 982

Query: 165  PPILPRIQE--QFQKNPDSYNGAVRE 188
            PP LP  +   + Q  P+   G + E
Sbjct: 983  PPALPPPESPPKVQPEPEPEPGLLLE 1008


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score = 33.9 bits (76), Expect = 0.23
 Identities = 23/77 (29%), Positives = 42/77 (54%), Gaps = 4/77 (5%)

Query: 59   QALVLQVFKTFDHMARQDDEKRRQELEEKIRRKE---EEEAKTVSAAAAEKEPVPVPVQE 115
            QAL  Q  +       Q++EKRRQ L+ ++   E   E+E K  + AAA K+ +   +++
Sbjct: 1570 QALKGQFERDLQARDEQNEEKRRQ-LQRQLHEYETELEDERKQRALAAAAKKKLEGDLKD 1628

Query: 116  IEIDSTTELDGHQEVEK 132
            +E+ + + + G +E  K
Sbjct: 1629 LELQADSAIKGREEAIK 1645


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.132    0.383 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,212,481
Number of Sequences: 37866
Number of extensions: 747066
Number of successful extensions: 5742
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 65
Number of HSP's successfully gapped in prelim test: 210
Number of HSP's that attempted gapping in prelim test: 4754
Number of HSP's gapped (non-prelim): 996
length of query: 361
length of database: 18,247,518
effective HSP length: 104
effective length of query: 257
effective length of database: 14,309,454
effective search space: 3677529678
effective search space used: 3677529678
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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