Guide to the Human Genome
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Name: NEK1 Sequence: fasta or formatted (1258aa) NCBI GI: 41872673
Description:

NIMA-related kinase 1

Referenced in:

Dual-Specificity Protein Kinases
Spindle, M phase, and Meiosis

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.7         72           2
 C cysteine            1.2         15           1
 D aspartate           5.2         66           2
 E glutamate          11.9        150           4
 F phenylalanine       2.9         37           2
 G glycine             5.6         70           2
 H histidine           2.9         37           3
 I isoleucine          5.8         73           2
 K lysine              8.7        110           2
 L leucine             8.3        104           2
 M methionine          1.6         20           1
 N asparagine          4.5         56           2
 P proline             4.3         54           2
 Q glutamine           5.4         68           3
 R arginine            5.6         71           2
 S serine              8.4        106           2
 T threonine           3.8         48           2
 V valine              5.3         67           2
 W tryptophan          0.7          9           1
 Y tyrosine            2.0         25           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   NIMA-related kinase 1 
NEK5                  0.143   NIMA-related kinase 5 
NEK3                  0.124   NIMA-related kinase 3 isoform b 
NEK3                  0.124   NIMA-related kinase 3 isoform a 
NEK3                  0.124   NIMA-related kinase 3 isoform a 
NEK4                  0.109   NIMA-related kinase 4 
NEK8                  0.088   NIMA-related kinase 8 
NEK9                  0.084   NIMA-related kinase 9 
NEK11                 0.079   NIMA-related kinase 11 isoform 2 
NEK11                 0.079   NIMA-related kinase 11 isoform 3 
NEK11                 0.079   NIMA-related kinase 11 isoform 1 
NEK2                  0.072   NIMA-related kinase 2 
NEK7                  0.065   NIMA-related kinase 7 
NEK6                  0.065   NIMA-related kinase 6 isoform 1 
NEK6                  0.065   NIMA-related kinase 6 isoform 2 
STK36                 0.055   serine/threonine kinase 36 
RPS6KA3               0.050   ribosomal protein S6 kinase, 90kDa, polypeptide 3 [Ho...
RPS6KA1               0.049   ribosomal protein S6 kinase, 90kDa, polypeptide 1 is...
RPS6KA1               0.049   ribosomal protein S6 kinase, 90kDa, polypeptide 1 is...
RPS6KA2               0.049   ribosomal protein S6 kinase, 90kDa, polypeptide 2 is...
RPS6KA2               0.049   ribosomal protein S6 kinase, 90kDa, polypeptide 2 is...
PLK3                  0.048   polo-like kinase 3 
PLK2                  0.048   polo-like kinase 2 
RPS6KA6               0.048   ribosomal protein S6 kinase polypeptide 6 
PLK4                  0.048   polo-like kinase 4 
RPS6KB2               0.046   ribosomal protein S6 kinase, 70kDa, polypeptide 2 [H...
SLK                   0.046   serine/threonine kinase 2 
PRKACG                0.046   protein kinase, cAMP-dependent, catalytic, gamma [Ho...
PRKACA                0.045   cAMP-dependent protein kinase catalytic subunit alph...
PRKACA                0.045   cAMP-dependent protein kinase catalytic subunit alpha...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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