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Search of human proteins with 122937512
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|122937512 myosin VIIB [Homo sapiens]
(2116 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|122937512 myosin VIIB [Homo sapiens] 4265 0.0
gi|189083802 myosin VIIA isoform 2 [Homo sapiens] 2286 0.0
gi|189083798 myosin VIIA isoform 1 [Homo sapiens] 2282 0.0
gi|189083800 myosin VIIA isoform 3 [Homo sapiens] 1218 0.0
gi|118402590 myosin XV [Homo sapiens] 614 e-175
gi|154354979 myosin X [Homo sapiens] 599 e-171
gi|215982794 myosin VA isoform 2 [Homo sapiens] 572 e-162
gi|215982791 myosin VA isoform 1 [Homo sapiens] 572 e-162
gi|153945715 myosin VC [Homo sapiens] 552 e-156
gi|122937345 myosin VB [Homo sapiens] 540 e-153
gi|134288892 myosin IIIB isoform 2 [Homo sapiens] 520 e-147
gi|124494247 myosin IC isoform b [Homo sapiens] 514 e-145
gi|124494238 myosin IC isoform a [Homo sapiens] 514 e-145
gi|124494240 myosin IC isoform c [Homo sapiens] 514 e-145
gi|194328685 myosin IB isoform 1 [Homo sapiens] 503 e-141
gi|240120050 myosin IB isoform 1 [Homo sapiens] 503 e-141
gi|134288915 myosin IIIB isoform 1 [Homo sapiens] 503 e-141
gi|44889481 myosin IB isoform 2 [Homo sapiens] 500 e-141
gi|145275208 myosin IIIA [Homo sapiens] 491 e-138
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 485 e-136
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 485 e-136
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 482 e-135
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 482 e-135
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 481 e-135
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 481 e-135
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 478 e-134
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 476 e-134
gi|27544941 myosin IF [Homo sapiens] 473 e-132
gi|254028267 myosin 1H [Homo sapiens] 467 e-131
gi|4885503 myosin IA [Homo sapiens] 464 e-130
>gi|122937512 myosin VIIB [Homo sapiens]
Length = 2116
Score = 4265 bits (11061), Expect = 0.0
Identities = 2116/2116 (100%), Positives = 2116/2116 (100%)
Query: 1 MSGFRLGDHVWLEPPSTHKTGVAIGGIIKEAKPGKVLVEDDEGKEHWIRAEDFGVLSPMH 60
MSGFRLGDHVWLEPPSTHKTGVAIGGIIKEAKPGKVLVEDDEGKEHWIRAEDFGVLSPMH
Sbjct: 1 MSGFRLGDHVWLEPPSTHKTGVAIGGIIKEAKPGKVLVEDDEGKEHWIRAEDFGVLSPMH 60
Query: 61 PNSVQGVDDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQVQ 120
PNSVQGVDDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQVQ
Sbjct: 61 PNSVQGVDDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQVQ 120
Query: 121 LYYSRHMGELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATISG 180
LYYSRHMGELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATISG
Sbjct: 121 LYYSRHMGELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATISG 180
Query: 181 QHSWIEQQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKS 240
QHSWIEQQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKS
Sbjct: 181 QHSWIEQQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKS 240
Query: 241 RVCRQAPEERNYHIFYCMLMGVSAEDKQLLSLGTPSEYHYLTMGNCTSCEGLNDAKDYAH 300
RVCRQAPEERNYHIFYCMLMGVSAEDKQLLSLGTPSEYHYLTMGNCTSCEGLNDAKDYAH
Sbjct: 241 RVCRQAPEERNYHIFYCMLMGVSAEDKQLLSLGTPSEYHYLTMGNCTSCEGLNDAKDYAH 300
Query: 301 IRSAMKILQFSDSESWDVIKLLAAILHLGNVGFMASVFENLDASDVMETPAFPTVMKLLE 360
IRSAMKILQFSDSESWDVIKLLAAILHLGNVGFMASVFENLDASDVMETPAFPTVMKLLE
Sbjct: 301 IRSAMKILQFSDSESWDVIKLLAAILHLGNVGFMASVFENLDASDVMETPAFPTVMKLLE 360
Query: 361 VQHQELRDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIFT 420
VQHQELRDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIFT
Sbjct: 361 VQHQELRDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIFT 420
Query: 421 PPAQDPKNVRRAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYRSE 480
PPAQDPKNVRRAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYRSE
Sbjct: 421 PPAQDPKNVRRAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYRSE 480
Query: 481 NISWDYIHYTDNRPTLDLLALKPMSIISLLDEESRFPQGTDLTMLQKLNSVHANNKAFLQ 540
NISWDYIHYTDNRPTLDLLALKPMSIISLLDEESRFPQGTDLTMLQKLNSVHANNKAFLQ
Sbjct: 481 NISWDYIHYTDNRPTLDLLALKPMSIISLLDEESRFPQGTDLTMLQKLNSVHANNKAFLQ 540
Query: 541 PKNIHDARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLREIFNLELAET 600
PKNIHDARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLREIFNLELAET
Sbjct: 541 PKNIHDARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLREIFNLELAET 600
Query: 601 KLGHGTIRQAKAGNHLFKSADSNKRPSTLGSQFKQSLDQLMKILTNCQPYFIRCIKPNEY 660
KLGHGTIRQAKAGNHLFKSADSNKRPSTLGSQFKQSLDQLMKILTNCQPYFIRCIKPNEY
Sbjct: 601 KLGHGTIRQAKAGNHLFKSADSNKRPSTLGSQFKQSLDQLMKILTNCQPYFIRCIKPNEY 660
Query: 661 KKPLLFDRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPNAMRMQLQGKL 720
KKPLLFDRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPNAMRMQLQGKL
Sbjct: 661 KKPLLFDRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPNAMRMQLQGKL 720
Query: 721 RQMTLGITDVWLRTDKDWKAGKTKIFLRDHQDTLLEVQRSQVLDRAALSIQKVLRGYRYR 780
RQMTLGITDVWLRTDKDWKAGKTKIFLRDHQDTLLEVQRSQVLDRAALSIQKVLRGYRYR
Sbjct: 721 RQMTLGITDVWLRTDKDWKAGKTKIFLRDHQDTLLEVQRSQVLDRAALSIQKVLRGYRYR 780
Query: 781 KEFLRQRRAAVTLQAWWRGYCNRRNFKLILVGFERLQAIARSQPLARQYQAMRQRTVQLQ 840
KEFLRQRRAAVTLQAWWRGYCNRRNFKLILVGFERLQAIARSQPLARQYQAMRQRTVQLQ
Sbjct: 781 KEFLRQRRAAVTLQAWWRGYCNRRNFKLILVGFERLQAIARSQPLARQYQAMRQRTVQLQ 840
Query: 841 ALCRGYLVRQQVQAKRRAVVVIQAHARGMAARRNFQQRKANAPLVIPAEGQKSQGALPAK 900
ALCRGYLVRQQVQAKRRAVVVIQAHARGMAARRNFQQRKANAPLVIPAEGQKSQGALPAK
Sbjct: 841 ALCRGYLVRQQVQAKRRAVVVIQAHARGMAARRNFQQRKANAPLVIPAEGQKSQGALPAK 900
Query: 901 KRRSIYDTVTDTEMVEKVFGFLPAMIGGQEGQASPHFEDLESKTQKLLEVDLDTVPMAEE 960
KRRSIYDTVTDTEMVEKVFGFLPAMIGGQEGQASPHFEDLESKTQKLLEVDLDTVPMAEE
Sbjct: 901 KRRSIYDTVTDTEMVEKVFGFLPAMIGGQEGQASPHFEDLESKTQKLLEVDLDTVPMAEE 960
Query: 961 PEEDVDGLAEYTFPKFAVTYFQKSASHTHIRRPLRYPLLYHEDDTDCLAALVIWNVILRF 1020
PEEDVDGLAEYTFPKFAVTYFQKSASHTHIRRPLRYPLLYHEDDTDCLAALVIWNVILRF
Sbjct: 961 PEEDVDGLAEYTFPKFAVTYFQKSASHTHIRRPLRYPLLYHEDDTDCLAALVIWNVILRF 1020
Query: 1021 MGDLPEPVLYARSSQQGSSVMRQIHDTLGREHGAQVPQHSRSAQVASQLNIGEEALEPDG 1080
MGDLPEPVLYARSSQQGSSVMRQIHDTLGREHGAQVPQHSRSAQVASQLNIGEEALEPDG
Sbjct: 1021 MGDLPEPVLYARSSQQGSSVMRQIHDTLGREHGAQVPQHSRSAQVASQLNIGEEALEPDG 1080
Query: 1081 LGADRPMSNLEKVHFIVGYAILRPSLRDEIYCQICKQLSENFKTSSLARGWILLSLCLGC 1140
LGADRPMSNLEKVHFIVGYAILRPSLRDEIYCQICKQLSENFKTSSLARGWILLSLCLGC
Sbjct: 1081 LGADRPMSNLEKVHFIVGYAILRPSLRDEIYCQICKQLSENFKTSSLARGWILLSLCLGC 1140
Query: 1141 FPPSERFMKYLLNFIGQGPATYGPFCAERLRRTYANGVRAEPPTWLELQAVKSKKHIPIQ 1200
FPPSERFMKYLLNFIGQGPATYGPFCAERLRRTYANGVRAEPPTWLELQAVKSKKHIPIQ
Sbjct: 1141 FPPSERFMKYLLNFIGQGPATYGPFCAERLRRTYANGVRAEPPTWLELQAVKSKKHIPIQ 1200
Query: 1201 VILATGESLTVPVDSASTSREMCMHIAHKQGLSDHLGFSLQVAVYDKFWSLGSGRDHMMD 1260
VILATGESLTVPVDSASTSREMCMHIAHKQGLSDHLGFSLQVAVYDKFWSLGSGRDHMMD
Sbjct: 1201 VILATGESLTVPVDSASTSREMCMHIAHKQGLSDHLGFSLQVAVYDKFWSLGSGRDHMMD 1260
Query: 1261 AIARCEQMAQERGESQRQSPWRIYFRKEFFTPWHDSREDPVSTELIYRQVLRGVWSGEYS 1320
AIARCEQMAQERGESQRQSPWRIYFRKEFFTPWHDSREDPVSTELIYRQVLRGVWSGEYS
Sbjct: 1261 AIARCEQMAQERGESQRQSPWRIYFRKEFFTPWHDSREDPVSTELIYRQVLRGVWSGEYS 1320
Query: 1321 FEKEEELVELLARHCYVQLGASAESKAVQELLPSCIPHKLYRTKPPDRWASLVTAACAKA 1380
FEKEEELVELLARHCYVQLGASAESKAVQELLPSCIPHKLYRTKPPDRWASLVTAACAKA
Sbjct: 1321 FEKEEELVELLARHCYVQLGASAESKAVQELLPSCIPHKLYRTKPPDRWASLVTAACAKA 1380
Query: 1381 PYTQKQVTPLAVREQVVDAARLQWPLLFSRLFEVITLSGPRLPKTQLILAVNWKGLCFLD 1440
PYTQKQVTPLAVREQVVDAARLQWPLLFSRLFEVITLSGPRLPKTQLILAVNWKGLCFLD
Sbjct: 1381 PYTQKQVTPLAVREQVVDAARLQWPLLFSRLFEVITLSGPRLPKTQLILAVNWKGLCFLD 1440
Query: 1441 QQEKMLLELSFPEVMGLATNREAQGGQRLLLSTMHEEYEFVSPSSVAIAELVALFLEGLK 1500
QQEKMLLELSFPEVMGLATNREAQGGQRLLLSTMHEEYEFVSPSSVAIAELVALFLEGLK
Sbjct: 1441 QQEKMLLELSFPEVMGLATNREAQGGQRLLLSTMHEEYEFVSPSSVAIAELVALFLEGLK 1500
Query: 1501 ERSIFAMALQDRKATDDTTLLAFKKGDLLVLTKKQGLLASENWTLGQNDRTGKTGLVPMA 1560
ERSIFAMALQDRKATDDTTLLAFKKGDLLVLTKKQGLLASENWTLGQNDRTGKTGLVPMA
Sbjct: 1501 ERSIFAMALQDRKATDDTTLLAFKKGDLLVLTKKQGLLASENWTLGQNDRTGKTGLVPMA 1560
Query: 1561 CLYTIPTVTKPSAQLLSLLAMSPEKRKLAAQEGQFTEPRPEEPPKEKLHTLEEFSYEFFR 1620
CLYTIPTVTKPSAQLLSLLAMSPEKRKLAAQEGQFTEPRPEEPPKEKLHTLEEFSYEFFR
Sbjct: 1561 CLYTIPTVTKPSAQLLSLLAMSPEKRKLAAQEGQFTEPRPEEPPKEKLHTLEEFSYEFFR 1620
Query: 1621 APEKDMVSMAVLPLARARGHLWAYSCEPLRQPLLKRVHANVDLWDIACQIFVAILRYMGD 1680
APEKDMVSMAVLPLARARGHLWAYSCEPLRQPLLKRVHANVDLWDIACQIFVAILRYMGD
Sbjct: 1621 APEKDMVSMAVLPLARARGHLWAYSCEPLRQPLLKRVHANVDLWDIACQIFVAILRYMGD 1680
Query: 1681 YPSRQAWPTLELTDQIFTLALQHPALQDEVYCQILKQLTHNSNRHSEERGWQLLWLCTGL 1740
YPSRQAWPTLELTDQIFTLALQHPALQDEVYCQILKQLTHNSNRHSEERGWQLLWLCTGL
Sbjct: 1681 YPSRQAWPTLELTDQIFTLALQHPALQDEVYCQILKQLTHNSNRHSEERGWQLLWLCTGL 1740
Query: 1741 FPPSKGLLPHAQKFIDTRRGKLLAPDCSRRIQKVLRTGPRKQPPHQVEVEAAEQNVSRIC 1800
FPPSKGLLPHAQKFIDTRRGKLLAPDCSRRIQKVLRTGPRKQPPHQVEVEAAEQNVSRIC
Sbjct: 1741 FPPSKGLLPHAQKFIDTRRGKLLAPDCSRRIQKVLRTGPRKQPPHQVEVEAAEQNVSRIC 1800
Query: 1801 HKIYFPNDTSEMLEVVANTRVRDVCDSIATRLQLASWEGCSLFIKISDKVISQKEGDFFF 1860
HKIYFPNDTSEMLEVVANTRVRDVCDSIATRLQLASWEGCSLFIKISDKVISQKEGDFFF
Sbjct: 1801 HKIYFPNDTSEMLEVVANTRVRDVCDSIATRLQLASWEGCSLFIKISDKVISQKEGDFFF 1860
Query: 1861 DSLREVSDWVKKNKPQKEGAPVTLPYQVYFMRKLWLNISPGKDVNADTILHYHQELPKYL 1920
DSLREVSDWVKKNKPQKEGAPVTLPYQVYFMRKLWLNISPGKDVNADTILHYHQELPKYL
Sbjct: 1861 DSLREVSDWVKKNKPQKEGAPVTLPYQVYFMRKLWLNISPGKDVNADTILHYHQELPKYL 1920
Query: 1921 RGFHKCSREDAIHLAGLIYKAQFNNDRSQLASVPKILRELVPENLTRLMSSEEWKKSILL 1980
RGFHKCSREDAIHLAGLIYKAQFNNDRSQLASVPKILRELVPENLTRLMSSEEWKKSILL
Sbjct: 1921 RGFHKCSREDAIHLAGLIYKAQFNNDRSQLASVPKILRELVPENLTRLMSSEEWKKSILL 1980
Query: 1981 AYDKHKDKTVEEAKVAFLKWICRWPTFGSAFFEVKQTSEPSYPDVILIAINRHGVLLIHP 2040
AYDKHKDKTVEEAKVAFLKWICRWPTFGSAFFEVKQTSEPSYPDVILIAINRHGVLLIHP
Sbjct: 1981 AYDKHKDKTVEEAKVAFLKWICRWPTFGSAFFEVKQTSEPSYPDVILIAINRHGVLLIHP 2040
Query: 2041 KTKDLLTTYPFTKISSWSSGSTYFHMALGSLGRGSRLLCETSLGYKMDDLLTSYVQQLLS 2100
KTKDLLTTYPFTKISSWSSGSTYFHMALGSLGRGSRLLCETSLGYKMDDLLTSYVQQLLS
Sbjct: 2041 KTKDLLTTYPFTKISSWSSGSTYFHMALGSLGRGSRLLCETSLGYKMDDLLTSYVQQLLS 2100
Query: 2101 AMNKQRGSKAPALAST 2116
AMNKQRGSKAPALAST
Sbjct: 2101 AMNKQRGSKAPALAST 2116
>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
Length = 2175
Score = 2286 bits (5925), Expect = 0.0
Identities = 1164/2193 (53%), Positives = 1543/2193 (70%), Gaps = 115/2193 (5%)
Query: 7 GDHVWLEPPSTHKTGVAIGGIIKEAKPGKVLVEDDEGKEHWIRAEDFGVLSPMHPNSVQG 66
GDHVW++ + V IG ++K G+V V DDE EHWI ++ + PMHP SV G
Sbjct: 7 GDHVWMDLRLGQEFDVPIGAVVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHG 66
Query: 67 VDDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQVQLYYSRH 126
V+DMIRLGDLNEAG++ NLLIRY+ H IYTYTGSILVAVNP+Q+L +Y+ E ++ Y ++
Sbjct: 67 VEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKK 126
Query: 127 MGELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATISGQHSWIE 186
+GE+PPH+FAIA+NCYF+MKRN RDQCCIISGESGAGKTE+TKLILQFLA ISGQHSWIE
Sbjct: 127 IGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISGQHSWIE 186
Query: 187 QQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKSRVCRQA 246
QQVLEA PILEAFGNAKTIRNDNSSRFGKYIDI+FN G IEGA+IEQ+LLEKSRVCRQA
Sbjct: 187 QQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQA 246
Query: 247 PEERNYHIFYCMLMGVSAEDKQLLSLGTPSEYHYLTMGNCTSCEGLNDAKDYAHIRSAMK 306
+ERNYH+FYCML G+S + K+ L LG S+Y+YL MGNC +CEG D+++YA+IRSAMK
Sbjct: 247 LDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSAMK 306
Query: 307 ILQFSDSESWDVIKLLAAILHLGNVGFMASVFENLDASDVMETPAFPTVMKLLEVQHQEL 366
+L F+D+E+W++ KLLAAILHLGN+ + A FENLDA +V+ +P+ T LLEV +L
Sbjct: 307 VLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPPDL 366
Query: 367 RDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIFTPPAQDP 426
CL T++ RGE V+ L+ QA D RDAFVKGIYG LF+WIV KINAAI+ PP+QD
Sbjct: 367 MSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDV 426
Query: 427 KNVRRAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYRSENISWDY 486
KN RR+IGLLDIFGFENF NSFEQLCINFANEHLQQFFV+HVF +EQEEY E+I W +
Sbjct: 427 KNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLH 486
Query: 487 IHYTDNRPTLDLLALKPMSIISLLDEESRFPQGTDLTMLQKLNSVHANNKAFLQPKNIHD 546
I +TDN+ LD++A KPM+IISL+DEES+FP+GTD TML KLNS H N ++ PKN H+
Sbjct: 487 IEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKNNHE 546
Query: 547 ARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLREIFNLELAETKLGHGT 606
+FGI HFAG VYY+ +GFLEKNRD L DI+ LV+SS+NKF+++IF ++A
Sbjct: 547 TQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQADVA-------- 598
Query: 607 IRQAKAGNHLFKSADSNKRPSTLGSQFKQSLDQLMKILTNCQPYFIRCIKPNEYKKPLLF 666
A++ KR TL SQFK+SL+ LM+ L CQP+F+RCIKPNE+KKP+LF
Sbjct: 599 -----------MGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLF 647
Query: 667 DRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPNAMRMQLQGKLRQMTLG 726
DR LC+RQLRYSGMMET+ IR++G+PIRY+F EF +R+ VLLP QG LR
Sbjct: 648 DRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQR 707
Query: 727 ITDVWLRTDKDWKAGKTKIFLRDHQDTLLEVQRSQVLDRAALSIQKVLRGYRYRKEFLRQ 786
+ + L T DW+ GKTKIFL+DH D LLEV+R + + + +QKV+RG++ R FL+
Sbjct: 708 MAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKL 767
Query: 787 RRAAVTLQAWWRGYCNRRNFKLILVGFERLQAIARSQPLARQYQAMRQRTVQLQALCRGY 846
+ AA +Q WRG+ R+N+ L+ +GF RLQA+ RS+ L +QY+ RQR +Q QA CR Y
Sbjct: 768 KNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAY 827
Query: 847 LVRQQVQAKRRAVVVIQAHARGMAARRNFQQRKAN------APLVIPAEGQKSQGALPAK 900
LVR+ + + AV+ +QA+ARGM ARR Q+ +A A + AE +K + + AK
Sbjct: 828 LVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEMSAK 887
Query: 901 K-----------------------------------------RRSIYDTVTDTEMVEKVF 919
K R+ ++ V ++MV+K+F
Sbjct: 888 KAKEEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQMERARHEPVNHSDMVDKMF 947
Query: 920 GFLPAMIG--GQEGQASPHFEDLESKTQKLLEVDLDT-VPMAEEPEEDVDGLAEYTFPKF 976
GFL G GQEGQA FEDLE ++++E DLD +P+ +E EED L+EY F KF
Sbjct: 948 GFLGTSGGLPGQEGQAPSGFEDLERGRREMVEEDLDAALPLPDEDEED---LSEYKFAKF 1004
Query: 977 AVTYFQKSASHTHIRRPLRYPLLYHEDDTDCLAALVIWNVILRFMGDLPEPVLYARSSQQ 1036
A TYFQ + +H++ RRPL+ PLLYH+D+ D LAAL +W ILRFMGDLPEP + S
Sbjct: 1005 AATYFQGTTTHSYTRRPLKQPLLYHDDEGDQLAALAVWITILRFMGDLPEPKYHTAMSDG 1064
Query: 1037 GSS--VMRQIHDTLGR------------EHGAQVPQHSRSA------------------- 1063
VM +I++TLG+ E AQ+P+ + +
Sbjct: 1065 SEKIPVMTKIYETLGKKTYKRELQALQGEGEAQLPEGQKKSSVRHKLVHLTLKKKSKLTE 1124
Query: 1064 QVASQLNIGEEALEPDGLGADRPMSNLEKVHFIVGYAILRPSLRDEIYCQICKQLSENFK 1123
+V +L+ GE ++ + + DRP SNLEK+HFI+G ILRP+LRDEIYCQI KQL+ N
Sbjct: 1125 EVTKRLHDGESTVQGNSMLEDRPTSNLEKLHFIIGNGILRPALRDEIYCQISKQLTHNPS 1184
Query: 1124 TSSLARGWILLSLCLGCFPPSERFMKYLLNFIGQGPATYGPFCAERLRRTYANGVRAEPP 1183
SS ARGWIL+SLC+GCF PSE+F+KYL NFI GP Y P+C ERLRRT+ NG R +PP
Sbjct: 1185 KSSYARGWILVSLCVGCFAPSEKFVKYLRNFIHGGPPGYAPYCEERLRRTFVNGTRTQPP 1244
Query: 1184 TWLELQAVKSKKHIPIQVILATGESLTVPVDSASTSREMCMHIAHKQGLSDHLGFSLQVA 1243
+WLELQA KSKK I + V G + T+ DSA+T++E+C +A K L D GFSL +A
Sbjct: 1245 SWLELQATKSKKPIMLPVTFMDGTTKTLLTDSATTAKELCNALADKISLKDRFGFSLYIA 1304
Query: 1244 VYDKFWSLGSGRDHMMDAIARCEQMAQERGESQRQSPWRIYFRKEFFTPWHDSREDPVST 1303
++DK SLGSG DH+MDAI++CEQ A+E+G +R +PWR++FRKE FTPWH ED V+T
Sbjct: 1305 LFDKVSSLGSGSDHVMDAISQCEQYAKEQGAQERNAPWRLFFRKEVFTPWHSPSEDNVAT 1364
Query: 1304 ELIYRQVLRGVWSGEYSFEKEEELVELLARHCYVQLGASAESKAVQELLPSCIPHK-LYR 1362
LIY+QV+RGV GEY EKE++L EL ++ +V G+ + + L+P+ IP + +
Sbjct: 1365 NLIYQQVVRGVKFGEYRCEKEDDLAELASQQYFVDYGSEMILERLLNLVPTYIPDREITP 1424
Query: 1363 TKPPDRWASLVTAACAKAPYTQKQVTPLAVREQVVDAARLQWPLLFSRLFEVITLSGPRL 1422
K ++WA L AA K Y Q++ V+E VV AR +WPLLFSR +E SGP L
Sbjct: 1425 LKTLEKWAQLAIAAHKKGIYAQRRTDAQKVKEDVVSYARFKWPLLFSRFYEAYKFSGPSL 1484
Query: 1423 PKTQLILAVNWKGLCFLDQQEKMLLELSFPEVMGLATNREAQG-GQRLLLSTMH-EEYEF 1480
PK +I+AVNW G+ F+D+QE++LLELSFPE+M ++++R A+ L+T+ +EY F
Sbjct: 1485 PKNDVIVAVNWTGVYFVDEQEQVLLELSFPEIMAVSSSRGAKTTAPSFTLATIKGDEYTF 1544
Query: 1481 VSPSSVAIAELVALFLEGLKERSIFAMALQDRK--ATDDTTLLAFKKGDLLVLTKKQG-L 1537
S ++ I +LV FLEGL++RS + +ALQD A +++ L+F KGDL++L G
Sbjct: 1545 TSSNAEDIRDLVVTFLEGLRKRSKYVVALQDNPNPAGEESGFLSFAKGDLIILDHDTGEQ 1604
Query: 1538 LASENWTLGQNDRTGKTGLVPMACLYTIPTVTKPSAQLLSLLAMSPEKRKLAAQEGQFTE 1597
+ + W G N+RT + G P +Y +PTVT P ++++L+ M+P++R+ + Q
Sbjct: 1605 VMNSGWANGINERTKQRGDFPTDSVYVMPTVTMPPREIVALVTMTPDQRQDVVRLLQLRT 1664
Query: 1598 PRPEEPPKEKLHTLEEFSYEFFRAPEKDMVSMAVLPLARARGHLWAYSCEPLRQPLLKRV 1657
PE + K +TLEEFSY++FR P K +S ++ AR + LW+++ EPL+Q LLK++
Sbjct: 1665 AEPEV--RAKPYTLEEFSYDYFRPPPKHTLSRVMVSKARGKDRLWSHTREPLKQALLKKL 1722
Query: 1658 HANVDLWDIACQIFVAILRYMGDYPSRQAWPTLELTDQIFTLALQHPALQDEVYCQILKQ 1717
+ +L AC F+A+L+YMGDYPS++ ELTDQIF L+ L+DE Y QILKQ
Sbjct: 1723 LGSEELSQEACLAFIAVLKYMGDYPSKRTRSVNELTDQIFEGPLKAEPLKDEAYVQILKQ 1782
Query: 1718 LTHNSNRHSEERGWQLLWLCTGLFPPSKGLLPHAQKFIDTRRGKLLAPDCSRRIQKVLRT 1777
LT N R+SEERGW+LLWLCTGLFPPS LLPH Q+F+ +R+ LA DC +R+QK LR
Sbjct: 1783 LTDNHIRYSEERGWELLWLCTGLFPPSNILLPHVQRFLQSRKHCPLAIDCLQRLQKALRN 1842
Query: 1778 GPRKQPPHQVEVEAAEQNVSRICHKIYFPNDTSEMLEVVANTRVRDVCDSIATRLQLASW 1837
G RK PPH VEVEA + ++I HK+YFP+DT E EV ++T+ +D C +IATRL L S
Sbjct: 1843 GSRKYPPHLVEVEAIQHKTTQIFHKVYFPDDTDEAFEVESSTKAKDFCQNIATRLLLKSS 1902
Query: 1838 EGCSLFIKISDKVISQKEGDFFFDSLREVSDWVKKNKPQKEGAPVTLPYQVYFMRKLWLN 1897
EG SLF+KI+DKV+S E DFFFD +R ++DW+KK +P K+G +L YQV+FM+KLW
Sbjct: 1903 EGFSLFVKIADKVLSVPENDFFFDFVRHLTDWIKKARPIKDGIVPSLTYQVFFMKKLWTT 1962
Query: 1898 ISPGKDVNADTILHYHQELPKYLRGFHKCSREDAIHLAGLIYKAQFNNDRSQLASVPKIL 1957
PGKD AD+I HY+QELPKYLRG+HKC+RE+ + L LIY+ +F D+S S+PK+L
Sbjct: 1963 TVPGKDPMADSIFHYYQELPKYLRGYHKCTREEVLQLGALIYRVKFEEDKSYFPSIPKLL 2022
Query: 1958 RELVPENLTRLMSSEEWKKSILLAYDKHKDKTVEEAKVAFLKWICRWPTFGSAFFEVKQT 2017
RELVP++L R +S ++WK+SI+ ++KH K+ EEAK+AFLK I +WPTFGSAFFE QT
Sbjct: 2023 RELVPQDLIRQVSPDDWKRSIVAYFNKHAGKSKEEAKLAFLKLIFKWPTFGSAFFE--QT 2080
Query: 2018 SEPSYPDVILIAINRHGVLLIHPKTKDLLTTYPFTKISSWSSGSTYFHMALGSLGRGSRL 2077
+EP++P+++LIAIN++GV LI PKTKD+LTT+PFTKIS+WSSG+TYFH+ +G+L RGS+L
Sbjct: 2081 TEPNFPEILLIAINKYGVSLIDPKTKDILTTHPFTKISNWSSGNTYFHITIGNLVRGSKL 2140
Query: 2078 LCETSLGYKMDDLLTSYVQQLLSAMNKQRGSKA 2110
LCETSLGYKMDDLLTSY+ Q+L+AM+KQRGS++
Sbjct: 2141 LCETSLGYKMDDLLTSYISQMLTAMSKQRGSRS 2173
>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
Length = 2215
Score = 2282 bits (5914), Expect = 0.0
Identities = 1166/2231 (52%), Positives = 1544/2231 (69%), Gaps = 151/2231 (6%)
Query: 7 GDHVWLEPPSTHKTGVAIGGIIKEAKPGKVLVEDDEGKEHWIRAEDFGVLSPMHPNSVQG 66
GDHVW++ + V IG ++K G+V V DDE EHWI ++ + PMHP SV G
Sbjct: 7 GDHVWMDLRLGQEFDVPIGAVVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHG 66
Query: 67 VDDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQVQLYYSRH 126
V+DMIRLGDLNEAG++ NLLIRY+ H IYTYTGSILVAVNP+Q+L +Y+ E ++ Y ++
Sbjct: 67 VEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKK 126
Query: 127 MGELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATISGQHSWIE 186
+GE+PPH+FAIA+NCYF+MKRN RDQCCIISGESGAGKTE+TKLILQFLA ISGQHSWIE
Sbjct: 127 IGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISGQHSWIE 186
Query: 187 QQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKSRVCRQA 246
QQVLEA PILEAFGNAKTIRNDNSSRFGKYIDI+FN G IEGA+IEQ+LLEKSRVCRQA
Sbjct: 187 QQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQA 246
Query: 247 PEERNYHIFYCMLMGVSAEDKQLLSLGTPSEYHYLTMGNCTSCEGLNDAKDYAHIRSAMK 306
+ERNYH+FYCML G+S + K+ L LG S+Y+YL MGNC +CEG D+++YA+IRSAMK
Sbjct: 247 LDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSAMK 306
Query: 307 ILQFSDSESWDVIKLLAAILHLGNVGFMASVFENLDASDVMETPAFPTVMKLLEVQHQEL 366
+L F+D+E+W++ KLLAAILHLGN+ + A FENLDA +V+ +P+ T LLEV +L
Sbjct: 307 VLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPPDL 366
Query: 367 RDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIFTPPAQDP 426
CL T++ RGE V+ L+ QA D RDAFVKGIYG LF+WIV KINAAI+ PP+QD
Sbjct: 367 MSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDV 426
Query: 427 KNVRRAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYRSENISWDY 486
KN RR+IGLLDIFGFENF NSFEQLCINFANEHLQQFFV+HVF +EQEEY E+I W +
Sbjct: 427 KNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLH 486
Query: 487 IHYTDNRPTLDLLALKPMSIISLLDEESRFPQGTDLTMLQKLNSVHANNKAFLQPKNIHD 546
I +TDN+ LD++A KPM+IISL+DEES+FP+GTD TML KLNS H N ++ PKN H+
Sbjct: 487 IEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKNNHE 546
Query: 547 ARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLREIFNLELAETKLGHGT 606
+FGI HFAG VYY+ +GFLEKNRD L DI+ LV+SS+NKF+++IF ++A
Sbjct: 547 TQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQADVA-------- 598
Query: 607 IRQAKAGNHLFKSADSNKRPSTLGSQFKQSLDQLMKILTNCQPYFIRCIKPNEYKKPLLF 666
A++ KR TL SQFK+SL+ LM+ L CQP+F+RCIKPNE+KKP+LF
Sbjct: 599 -----------MGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLF 647
Query: 667 DRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPNAMRMQLQGKLRQMTLG 726
DR LC+RQLRYSGMMET+ IR++G+PIRY+F EF +R+ VLLP QG LR
Sbjct: 648 DRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQR 707
Query: 727 ITDVWLRTDKDWKAGKTKIFLRDHQDTLLEVQRSQVLDRAALSIQKVLRGYRYRKEFLRQ 786
+ + L T DW+ GKTKIFL+DH D LLEV+R + + + +QKV+RG++ R FL+
Sbjct: 708 MAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKL 767
Query: 787 RRAAVTLQAWWRGYCNRRNFKLILVGFERLQAIARSQPLARQYQAMRQRTVQLQALCRGY 846
+ AA +Q WRG+ R+N+ L+ +GF RLQA+ RS+ L +QY+ RQR +Q QA CR Y
Sbjct: 768 KNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAY 827
Query: 847 LVRQQVQAKRRAVVVIQAHARGMAARRNFQQRKAN------APLVIPAEGQKSQGALPAK 900
LVR+ + + AV+ +QA+ARGM ARR Q+ +A A + AE +K + + AK
Sbjct: 828 LVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEMSAK 887
Query: 901 K-----------------------------------------RRSIYDTVTDTEMVEKVF 919
K R+ ++ V ++MV+K+F
Sbjct: 888 KAKEEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQMERARHEPVNHSDMVDKMF 947
Query: 920 GFLPAMIG--GQEGQASPHFEDLESKTQKLLEVDLDT-VPMAEEPEEDVDGLAEYTFPKF 976
GFL G GQEGQA FEDLE ++++E DLD +P+ +E EED L+EY F KF
Sbjct: 948 GFLGTSGGLPGQEGQAPSGFEDLERGRREMVEEDLDAALPLPDEDEED---LSEYKFAKF 1004
Query: 977 AVTYFQKSASHTHIRRPLRYPLLYHEDDTDCLAALVIWNVILRFMGDLPEPVLYARSSQQ 1036
A TYFQ + +H++ RRPL+ PLLYH+D+ D LAAL +W ILRFMGDLPEP + S
Sbjct: 1005 AATYFQGTTTHSYTRRPLKQPLLYHDDEGDQLAALAVWITILRFMGDLPEPKYHTAMSDG 1064
Query: 1037 GSS--VMRQIHDTLGR------------EHGAQVPQHSRSA------------------- 1063
VM +I++TLG+ E AQ+P+ + +
Sbjct: 1065 SEKIPVMTKIYETLGKKTYKRELQALQGEGEAQLPEGQKKSSVRHKLVHLTLKKKSKLTE 1124
Query: 1064 QVASQLNIGEEALEPDGLGADRPMSNLEKVHFIVGYAILRPSLRDEIYCQICKQLSENFK 1123
+V +L+ GE ++ + + DRP SNLEK+HFI+G ILRP+LRDEIYCQI KQL+ N
Sbjct: 1125 EVTKRLHDGESTVQGNSMLEDRPTSNLEKLHFIIGNGILRPALRDEIYCQISKQLTHNPS 1184
Query: 1124 TSSLARGWILLSLCLGCFPPSERFMKYLLNFIGQGPATYGPFCAERLRRTYANGVRAEPP 1183
SS ARGWIL+SLC+GCF PSE+F+KYL NFI GP Y P+C ERLRRT+ NG R +PP
Sbjct: 1185 KSSYARGWILVSLCVGCFAPSEKFVKYLRNFIHGGPPGYAPYCEERLRRTFVNGTRTQPP 1244
Query: 1184 TWLELQAVKSKKHIPIQVILATGESLTVPVDSASTSREMCMHIAHKQGLSDHLGFSLQVA 1243
+WLELQA KSKK I + V G + T+ DSA+T++E+C +A K L D GFSL +A
Sbjct: 1245 SWLELQATKSKKPIMLPVTFMDGTTKTLLTDSATTAKELCNALADKISLKDRFGFSLYIA 1304
Query: 1244 VYDKFWSLGSGRDHMMDAIARCEQMAQERGESQRQSPWRIYFRKEFFTPWHDSREDPVST 1303
++DK SLGSG DH+MDAI++CEQ A+E+G +R +PWR++FRKE FTPWH ED V+T
Sbjct: 1305 LFDKVSSLGSGSDHVMDAISQCEQYAKEQGAQERNAPWRLFFRKEVFTPWHSPSEDNVAT 1364
Query: 1304 ELIYRQVLRGVWSGEYSFEKEEELVELLARHCYVQLGASAESKAVQELLPSCIP-HKLYR 1362
LIY+QV+RGV GEY EKE++L EL ++ +V G+ + + L+P+ IP ++
Sbjct: 1365 NLIYQQVVRGVKFGEYRCEKEDDLAELASQQYFVDYGSEMILERLLNLVPTYIPDREITP 1424
Query: 1363 TKPPDRWASLVTAACAKAPYTQKQVTPLAVREQVVDAARLQWPLLFSRLFEVITLSGPRL 1422
K ++WA L AA K Y Q++ V+E VV AR +WPLLFSR +E SGP L
Sbjct: 1425 LKTLEKWAQLAIAAHKKGIYAQRRTDAQKVKEDVVSYARFKWPLLFSRFYEAYKFSGPSL 1484
Query: 1423 PKTQLILAVNWKGLCFLDQQEKMLLELSFPEVMGLATNREAQGGQRL------------- 1469
PK +I+AVNW G+ F+D+QE++LLELSFPE+M ++++RE + L
Sbjct: 1485 PKNDVIVAVNWTGVYFVDEQEQVLLELSFPEIMAVSSSRECRVWLSLGCSDLGCAAPHSG 1544
Query: 1470 ---------------------------LLSTMHEEYEFVSPSSVAIAELVALFLEGLKER 1502
L + +EY F S ++ I +LV FLEGL++R
Sbjct: 1545 WAGLTPAGPCSPCWSCRGAKTTAPSFTLATIKGDEYTFTSSNAEDIRDLVVTFLEGLRKR 1604
Query: 1503 SIFAMALQD--RKATDDTTLLAFKKGDLLVLTKKQG-LLASENWTLGQNDRTGKTGLVPM 1559
S + +ALQD A +++ L+F KGDL++L G + + W G N+RT + G P
Sbjct: 1605 SKYVVALQDNPNPAGEESGFLSFAKGDLIILDHDTGEQVMNSGWANGINERTKQRGDFPT 1664
Query: 1560 ACLYTIPTVTKPSAQLLSLLAMSPEKRKLAAQEGQFTEPRPEEPPKEKLHTLEEFSYEFF 1619
+Y +PTVT P ++++L+ M+P++R+ + Q PE + K +TLEEFSY++F
Sbjct: 1665 DSVYVMPTVTMPPREIVALVTMTPDQRQDVVRLLQLRTAEPE--VRAKPYTLEEFSYDYF 1722
Query: 1620 RAPEKDMVSMAVLPLARARGHLWAYSCEPLRQPLLKRVHANVDLWDIACQIFVAILRYMG 1679
R P K +S ++ AR + LW+++ EPL+Q LLK++ + +L AC F+A+L+YMG
Sbjct: 1723 RPPPKHTLSRVMVSKARGKDRLWSHTREPLKQALLKKLLGSEELSQEACLAFIAVLKYMG 1782
Query: 1680 DYPSRQAWPTLELTDQIFTLALQHPALQDEVYCQILKQLTHNSNRHSEERGWQLLWLCTG 1739
DYPS++ ELTDQIF L+ L+DE Y QILKQLT N R+SEERGW+LLWLCTG
Sbjct: 1783 DYPSKRTRSVNELTDQIFEGPLKAEPLKDEAYVQILKQLTDNHIRYSEERGWELLWLCTG 1842
Query: 1740 LFPPSKGLLPHAQKFIDTRRGKLLAPDCSRRIQKVLRTGPRKQPPHQVEVEAAEQNVSRI 1799
LFPPS LLPH Q+F+ +R+ LA DC +R+QK LR G RK PPH VEVEA + ++I
Sbjct: 1843 LFPPSNILLPHVQRFLQSRKHCPLAIDCLQRLQKALRNGSRKYPPHLVEVEAIQHKTTQI 1902
Query: 1800 CHKIYFPNDTSEMLEVVANTRVRDVCDSIATRLQLASWEGCSLFIKISDKVISQKEGDFF 1859
HK+YFP+DT E EV ++T+ +D C +IATRL L S EG SLF+KI+DKV+S E DFF
Sbjct: 1903 FHKVYFPDDTDEAFEVESSTKAKDFCQNIATRLLLKSSEGFSLFVKIADKVLSVPENDFF 1962
Query: 1860 FDSLREVSDWVKKNKPQKEGAPVTLPYQVYFMRKLWLNISPGKDVNADTILHYHQELPKY 1919
FD +R ++DW+KK +P K+G +L YQV+FM+KLW PGKD AD+I HY+QELPKY
Sbjct: 1963 FDFVRHLTDWIKKARPIKDGIVPSLTYQVFFMKKLWTTTVPGKDPMADSIFHYYQELPKY 2022
Query: 1920 LRGFHKCSREDAIHLAGLIYKAQFNNDRSQLASVPKILRELVPENLTRLMSSEEWKKSIL 1979
LRG+HKC+RE+ + L LIY+ +F D+S S+PK+LRELVP++L R +S ++WK+SI+
Sbjct: 2023 LRGYHKCTREEVLQLGALIYRVKFEEDKSYFPSIPKLLRELVPQDLIRQVSPDDWKRSIV 2082
Query: 1980 LAYDKHKDKTVEEAKVAFLKWICRWPTFGSAFFEVKQTSEPSYPDVILIAINRHGVLLIH 2039
++KH K+ EEAK+AFLK I +WPTFGSAFFEVKQT+EP++P+++LIAIN++GV LI
Sbjct: 2083 AYFNKHAGKSKEEAKLAFLKLIFKWPTFGSAFFEVKQTTEPNFPEILLIAINKYGVSLID 2142
Query: 2040 PKTKDLLTTYPFTKISSWSSGSTYFHMALGSLGRGSRLLCETSLGYKMDDLLTSYVQQLL 2099
PKTKD+LTT+PFTKIS+WSSG+TYFH+ +G+L RGS+LLCETSLGYKMDDLLTSY+ Q+L
Sbjct: 2143 PKTKDILTTHPFTKISNWSSGNTYFHITIGNLVRGSKLLCETSLGYKMDDLLTSYISQML 2202
Query: 2100 SAMNKQRGSKA 2110
+AM+KQRGS++
Sbjct: 2203 TAMSKQRGSRS 2213
>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
Length = 1204
Score = 1218 bits (3152), Expect = 0.0
Identities = 642/1219 (52%), Positives = 831/1219 (68%), Gaps = 117/1219 (9%)
Query: 7 GDHVWLEPPSTHKTGVAIGGIIKEAKPGKVLVEDDEGKEHWIRAEDFGVLSPMHPNSVQG 66
GDHVW++ + V IG ++K G+V V DDE EHWI ++ + PMHP SV G
Sbjct: 7 GDHVWMDLRLGQEFDVPIGAVVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHG 66
Query: 67 VDDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQVQLYYSRH 126
V+DMIRLGDLNEAG++ NLLIRY+ H IYTYTGSILVAVNP+Q+L +Y+ E ++ Y ++
Sbjct: 67 VEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKK 126
Query: 127 MGELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATISGQHSWIE 186
+GE+PPH+FAIA+NCYF+MKRN RDQCCIISGESGAGKTE+TKLILQFLA ISGQHSWIE
Sbjct: 127 IGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISGQHSWIE 186
Query: 187 QQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKSRVCRQA 246
QQVLEA PILEAFGNAKTIRNDNSSRFGKYIDI+FN G IEGA+IEQ+LLEKSRVCRQA
Sbjct: 187 QQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQA 246
Query: 247 PEERNYHIFYCMLMGVSAEDKQLLSLGTPSEYHYLTMGNCTSCEGLNDAKDYAHIRSAMK 306
+ERNYH+FYCML G+S + K+ L LG S+Y+YL MGNC +CEG D+++YA+IRSAMK
Sbjct: 247 LDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSAMK 306
Query: 307 ILQFSDSESWDVIKLLAAILHLGNVGFMASVFENLDASDVMETPAFPTVMKLLEVQHQEL 366
+L F+D+E+W++ KLLAAILHLGN+ + A FENLDA +V+ +P+ T LLEV +L
Sbjct: 307 VLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPPDL 366
Query: 367 RDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIFTPPAQDP 426
CL T++ RGE V+ L+ QA D RDAFVKGIYG LF+WIV KINAAI+ PP+QD
Sbjct: 367 MSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDV 426
Query: 427 KNVRRAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYRSENISWDY 486
KN RR+IGLLDIFGFENF NSFEQLCINFANEHLQQFFV+HVF +EQEEY E+I W +
Sbjct: 427 KNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLH 486
Query: 487 IHYTDNRPTLDLLALKPMSIISLLDEESRFPQGTDLTMLQKLNSVHANNKAFLQPKNIHD 546
I +TDN+ LD++A KPM+IISL+DEES+FP+GTD TML KLNS H N ++ PKN H+
Sbjct: 487 IEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKNNHE 546
Query: 547 ARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLREIFNLELAETKLGHGT 606
+FGI HFAG VYY+ +GFLEKNRD L DI+ LV+SS+NKF+++IF ++A
Sbjct: 547 TQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQADVA-------- 598
Query: 607 IRQAKAGNHLFKSADSNKRPSTLGSQFKQSLDQLMKILTNCQPYFIRCIKPNEYKKPLLF 666
A++ KR TL SQFK+SL+ LM+ L CQP+F+RCIKPNE+KKP+LF
Sbjct: 599 -----------MGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLF 647
Query: 667 DRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPNAMRMQLQGKLRQMTLG 726
DR LC+RQLRYSGMMET+ IR++G+PIRY+F EF +R+ VLLP QG LR
Sbjct: 648 DRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQR 707
Query: 727 ITDVWLRTDKDWKAGKTKIFLRDHQDTLLEVQRSQVLDRAALSIQKVLRGYRYRKEFLRQ 786
+ + L T DW+ GKTKIFL+DH D LLEV+R + + + +QKV+RG++ R FL+
Sbjct: 708 MAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKL 767
Query: 787 RRAAVTLQAWWRGYCNRRNFKLILVGFERLQAIARSQPLARQYQAMRQRTVQLQALCRGY 846
+ AA +Q WRG+ R+N+ L+ +GF RLQA+ RS+ L +QY+ RQR +Q QA CR Y
Sbjct: 768 KNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAY 827
Query: 847 LVRQQVQAKRRAVVVIQAHARGMAARRNFQQRKAN------APLVIPAEGQKSQGALPAK 900
LVR+ + + AV+ +QA+ARGM ARR Q+ +A A + AE +K + + AK
Sbjct: 828 LVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEMSAK 887
Query: 901 K-----------------------------------------RRSIYDTVTDTEMVEKVF 919
K R+ ++ V ++MV+K+F
Sbjct: 888 KAKEEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQMERARHEPVNHSDMVDKMF 947
Query: 920 GFLPAMIG--GQEGQASPHFEDLESKTQKLLEVDLDT-VPMAEEPEEDVDGLAEYTFPKF 976
GFL G GQEGQA FEDLE ++++E DLD +P+ +E EED L+EY F KF
Sbjct: 948 GFLGTSGGLPGQEGQAPSGFEDLERGRREMVEEDLDAALPLPDEDEED---LSEYKFAKF 1004
Query: 977 AVTYFQKSASHTHIRRPLRYPLLYHEDDTDCLAALVIWNVILRFMGDLPEPVLYARSSQQ 1036
A TYFQ + +H++ RRPL+ PLLYH+D+ D LAAL +W ILRFMGDLPEP Y +
Sbjct: 1005 AATYFQGTTTHSYTRRPLKQPLLYHDDEGDQLAALAVWITILRFMGDLPEP-KYHTAMSD 1063
Query: 1037 GSS---VMRQIHDTLGR------------EHGAQVPQHSRSA------------------ 1063
GS VM +I++TLG+ E AQ+P+ + +
Sbjct: 1064 GSEKIPVMTKIYETLGKKTYKRELQALQGEGEAQLPEGQKKSSVRHKLVHLTLKKKSKLT 1123
Query: 1064 -QVASQLNIGEEALEPDGLGADRPMSNLEKVHFIVGYAILRPSLR---------DEIYCQ 1113
+V +L+ GE ++ + + DRP SNLEK+HFI+G ILRP+LR + CQ
Sbjct: 1124 EEVTKRLHDGESTVQGNSMLEDRPTSNLEKLHFIIGNGILRPALRSVPESLLVAEWCLCQ 1183
Query: 1114 ICKQLSE-NFKTSSLARGW 1131
K+LS+ +SL W
Sbjct: 1184 PSKRLSQAGLGLASLLASW 1202
>gi|118402590 myosin XV [Homo sapiens]
Length = 3530
Score = 614 bits (1583), Expect = e-175
Identities = 408/1218 (33%), Positives = 625/1218 (51%), Gaps = 166/1218 (13%)
Query: 66 GVDDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQVQLYYSR 125
GV+DM +L DL E ++ NL IR++++ IYTY GSILV+VNP+Q+ +Y EQVQ Y R
Sbjct: 1223 GVEDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNGR 1282
Query: 126 HMGELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATISGQHSWI 185
+GE PPH+FA+AN + M K++QC IISGESG+GKTE TKLIL++LA ++ + +
Sbjct: 1283 ALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMNQKREVM 1342
Query: 186 EQ-QVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKSRVCR 244
+Q ++LEA P+LE+FGNAKT+RNDNSSRFGK+++I+ GVI GA Q+LLEKSR+
Sbjct: 1343 QQIKILEATPLLESFGNAKTVRNDNSSRFGKFVEIFLE-GGVISGAITSQYLLEKSRIVF 1401
Query: 245 QAPEERNYHIFYCMLMGVSAEDKQLLSLGTPSEYHYLTMGNCTSCEGLNDAKDYAHIRSA 304
QA ERNYHIFY +L G+ A+ +Q SL Y+YL G G +DA D+ + +A
Sbjct: 1402 QAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIAGKSDADDFRRLLAA 1461
Query: 305 MKILQFSDSESWDVIKLLAAILHLGNVGFMASVFENLDASDVMETPAFPTVMKLLEVQHQ 364
M++L FS + + ++LA+ILHLGNV F + + + V+ V +LL++ +
Sbjct: 1462 MEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAREIQAVAELLQISPE 1521
Query: 365 ELRDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIFTPPAQ 424
L+ + E + L + A D RDA K +Y LF W++ ++NA +
Sbjct: 1522 GLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVNALV------ 1575
Query: 425 DPKNVRRAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYRSENISW 484
P+ +I +LDI+GFE+ NSFEQLCIN+ANE+LQ F + VF EQEEY E I W
Sbjct: 1576 SPRQDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIREQIDW 1635
Query: 485 DYIHYTDNRPTLDLLALKPMSIISLLDEESRFPQGTDLTMLQKLNSVHANNKAFLQPKNI 544
I + DN+P ++L++LKP I+ +LD++ FPQ TD T LQK + H N + +PK +
Sbjct: 1636 QEITFADNQPCINLISLKPYGILRILDDQCCFPQATDHTFLQKCHYHHGANPLYSKPK-M 1694
Query: 545 HDARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLREIFNL---ELAETK 601
F I H+AG+V YQ FL+KN D + D+L L S+ + + +F+ + A +
Sbjct: 1695 PLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVAHLFSSHAPQAAPQR 1754
Query: 602 LGHGTIRQAKAGNHLFKSADSNKRPSTLGSQFKQSLDQLMKILTNCQPYFIRCIKPNEYK 661
LG ++ + L+K+ T+ ++F+QSL L++ + C P F+RC+KPN K
Sbjct: 1755 LG-----KSSSVTRLYKA-------HTVAAKFQQSLLDLVEKMERCNPLFMRCLKPNHKK 1802
Query: 662 KPLLFDRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPNAMRMQLQGKLR 721
+P LF+ ++ + QLRYSG++ETV IRK GFP+R F+ F R+ L+ A++ L
Sbjct: 1803 EPGLFEPDVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLV--ALKHDLPANGD 1860
Query: 722 QMTLGITDVWLRTDKDWKAGKTKIFLRDHQDTLLEVQRSQVLDRAALSIQKVLRGYRYRK 781
++ + ++ G +K+FL++H LLE R VL+ AAL++Q+ LRG+ ++
Sbjct: 1861 MCVSVLSRLCKVMPNMYRVGVSKLFLKEHLYQLLESMREHVLNLAALTLQRCLRGFFIKR 1920
Query: 782 EFLRQRRAAVTLQAWWRGYCNRRNFKLILVGFERLQAIARSQPLARQYQAMRQRTVQLQA 841
F R + LQ+ RGY R+ ++ + + +++ + R+Y +R + +
Sbjct: 1921 RFRSLRHKIILLQSRARGYLARQRYQQMRRSLVKFRSLVHAYVSRRRYLKLR---AEWRC 1977
Query: 842 LCRGYLVRQQVQAKRRAVVVIQAHARGMAARRNFQQRKANAPLVIPAEGQKSQGALPAKK 901
G L+ +Q + +R VV + L +PAE
Sbjct: 1978 QVEGALLWEQEELSKREVVAV-------------------GHLEVPAE------------ 2006
Query: 902 RRSIYDTVTDTEMVEKVFGFLPAMIG---GQEGQASP-HFEDLESKTQKLLEVDLDTVPM 957
+ G L A+ G Q Q +P L+++ + L +D++ PM
Sbjct: 2007 ----------------LAGLLQAVAGLGLAQVPQVAPVRTPRLQAEPRVTLPLDINNYPM 2050
Query: 958 AEEPEEDVDGLAEYTFPKFAVTYFQKSASHTHIRRPLRYPLLYHEDDTDCLAALVIWNVI 1017
A KF +F K + + PLR PL + A+ I+ +I
Sbjct: 2051 A----------------KFVQCHF-KEPAFGMLTVPLRTPLTQLPAEHHA-EAVSIFKLI 2092
Query: 1018 LRFMGDLPEPVLY-ARSSQQGSSVMRQIHDTLGREHGAQVPQHSRSAQVASQLNIGEEAL 1076
LRFMGD P L+ AR + G+ ++++ G VP+
Sbjct: 2093 LRFMGD---PHLHGARENIFGNYIVQK---------GLAVPE------------------ 2122
Query: 1077 EPDGLGADRPMSNLEKVHFIVGYAILRPSLRDEIYCQICKQLSENFKTSSLARGWILLSL 1136
LRDEI Q+ Q+ N + RGW+LL+
Sbjct: 2123 -----------------------------LRDEILAQLANQVWHNHNAHNAERGWLLLAA 2153
Query: 1137 CLGCFPPSERFMKYLLNFIGQ-GPATYGPFCAERLRRTY-------ANGVRAEPPTWLEL 1188
CL F PS F KYLL F+ G + C RL + + R PPT LE
Sbjct: 2154 CLSGFAPSPCFNKYLLKFVSDYGRNGFQAVCQHRLMQAMGRAQQQGSGAARTLPPTQLEW 2213
Query: 1189 QAVKSKKHIPIQVILATGESLTVPVDSASTSREMCMHIAHKQGLSDHLGFSLQVAVYDKF 1248
A K + + V G+ + PV S ST E+ I +GL+D
Sbjct: 2214 TATYEKASMALDVGCFNGDQFSCPVHSWSTGEEVAGDILRHRGLADGWRGWTVAMKNGVQ 2273
Query: 1249 WSLGSGRDHMMDAIARCE 1266
W+ +G D+++D ++ E
Sbjct: 2274 WAELAGHDYVLDLVSDLE 2291
Score = 186 bits (471), Expect = 3e-46
Identities = 218/904 (24%), Positives = 379/904 (41%), Gaps = 144/904 (15%)
Query: 1277 RQSPWRIYFRKEFFTPWHDSREDPVSTELIYRQVLRGVWSGEYSFEKEEELVELLARHCY 1336
+ +PW+I+ RKE F P DS PV +L++RQ+L S E+E + + A
Sbjct: 2685 QDAPWKIFLRKEVFYP-KDSYSHPVQLDLLFRQILHDTLSEACLRISEDERLRMKALFAQ 2743
Query: 1337 VQLGASAESKAVQELLPSCIPHKLYRTKPPDRWASLVTAACAKAPYTQKQVTPLAVREQV 1396
QL TQK + +V+ V
Sbjct: 2744 NQLD------------------------------------------TQKPLVTESVKRAV 2761
Query: 1397 VDAARLQWPLLFSRLFEVITLSGPRLPKTQLILAVNWKGLCFLDQ---------QEKMLL 1447
V AR W + FSR+F G + +LAV+ G+ L Q ++L
Sbjct: 2762 VSTARDTWEVYFSRIFPATGSVGTGVQ----LLAVSHVGIKLLRMVKGGQEAGGQLRVLR 2817
Query: 1448 ELSFPEVMGLATNREAQGGQRLLLSTMHEEYEFVSPSSVAIAELVALFLEGLKERSIFAM 1507
SF +++ + + L + E+ S + + LV F+ LK+ S + +
Sbjct: 2818 AYSFADILFVTMPSQ----NMLEFNLASEKVILFSARAHQVKTLVDDFILELKKDSDYVV 2873
Query: 1508 ALQDRKATDDTTLLAFKKGDLLVL---------------TKKQGLLASE--------NWT 1544
A+++ +D LLAF KGD++ L +++ + E W
Sbjct: 2874 AVRNF-LPEDPALLAFHKGDIIHLQPLEPPRVGYSAGCVVRRKVVYLEELRRRGPDFGWR 2932
Query: 1545 LGQ-NDRTGK--TGLV-PMACLYTIPTVTKPSAQLLSLLAMSPEKRKLAAQEGQFTEPRP 1600
G + R G+ + LV P A + T+P + +A + A + G+ E P
Sbjct: 2933 FGTIHGRVGRFPSELVQPAAAPDFLQLPTEPGRGRAAAVAAAVASAAAAQEVGRRREGPP 2992
Query: 1601 ---------EEPPKEKLHTLEEFSYEFFRAPEKDMVSMAVLPL-----ARARGHLWAYSC 1646
E+ +T+ EF+ ++FR P++ L +R + ++
Sbjct: 2993 VRARSADHGEDALALPPYTMLEFAQKYFRDPQRRPQDGLRLKSKEPRESRTLEDMLCFTK 3052
Query: 1647 EPLRQPLLKRVHANVDLWDIACQIFVAILRYMGDYPSRQAWPTLELTDQIFTLALQHPAL 1706
PL++ L++ ++ L +A +F+A++R+MGD P + L++ + L H +
Sbjct: 3053 TPLQESLIEL--SDSSLSKMATDMFLAVMRFMGDAPLK-GQSDLDVLCNLLKLCGDHEVM 3109
Query: 1707 QDEVYCQILKQLTHN--SNRHSEERGWQLLWLCTGLFPPSKGLLPHAQKFID--TRRGKL 1762
+DE YCQ++KQ+T N S + S +RGW+LL++ T S+ L PH +F+ +R L
Sbjct: 3110 RDECYCQVVKQITDNTSSKQDSCQRGWRLLYIVTAYHSCSEVLHPHLTRFLQDVSRTPGL 3169
Query: 1763 ----LAPDCSRRIQKVLRTGPRKQPPHQVEVEAAEQNVSRICHKIYFPNDTSEMLEVVAN 1818
+A C + +QK LR G R + P +E+ A S P L++
Sbjct: 3170 PFQGIAKACEQNLQKTLRFGGRLELPSSIELRAMLAGRSSKRQLFLLPGGLERHLKIKTC 3229
Query: 1819 TRVRDVCDSIATRLQLASWEGCSLFIKISDKVISQKEGDFFFDSLREVSDWVKKNKPQKE 1878
T DV + I + L E + ++ V++ + S R V Q +
Sbjct: 3230 TVALDVVEEICAEMALTRPEAFNEYVIF---VVTNRGQHVCPLSRRAYILDVASEMEQVD 3286
Query: 1879 GAPVTLPYQVYFMRKLWLNISPGKDVNADTI-LHYHQELPKYLRGFHK---CSR------ 1928
G Y ++F R LW P K N + +HY+Q LP YL+G SR
Sbjct: 3287 GG-----YMLWFRRVLW--DQPLKFENELYVTMHYNQVLPDYLKGLFSSVPASRPSEQLL 3339
Query: 1929 EDAIHLAGLIYKAQFNNDRSQLASVPKILRELVPENLTRLMSSEEWKKSILLAYDKHKDK 1988
+ LA L ++A+ D L SV ++ +E +P L R + W + + +
Sbjct: 3340 QQVSKLASLQHRAK---DHFYLPSVREV-QEYIPAQLYRTTAGSTWLNLVSQHRQQTQAL 3395
Query: 1989 TVEEAKVAFLKWICRWPTFGSAFFEVKQTSEPSYPDVILIAINRHGVLLIHPKTKDLLTT 2048
+ +A+ FL + P FGS+FF ++ S + P ++AIN +G+ + +T +L+
Sbjct: 3396 SPHQARAQFLGLLSALPMFGSSFFFIQSCSNIAVPAPCILAINHNGLNFLSTETHELMVK 3455
Query: 2049 YPFTKISSW-------SSGSTYFHMALGSLGRGSRLLCETSLGYKMDDLLTSYVQQLLSA 2101
+P +I S +S Y +ALG + L + G ++ ++ +V+ LLSA
Sbjct: 3456 FPLKEIQSTRTQRPTANSSYPYVEIALGDVAAQRTLQLQLEQGLELCRVVAVHVENLLSA 3515
Query: 2102 MNKQ 2105
K+
Sbjct: 3516 HEKR 3519
Score = 72.8 bits (177), Expect = 3e-12
Identities = 93/383 (24%), Positives = 166/383 (43%), Gaps = 50/383 (13%)
Query: 1106 LRDEIYCQICKQLSEN--FKTSSLARGWILLSLCLGCFPPSERFMKYLLNFIGQGPATYG 1163
+RDE YCQ+ KQ+++N K S RGW LL + SE +L F+ T G
Sbjct: 3109 MRDECYCQVVKQITDNTSSKQDSCQRGWRLLYIVTAYHSCSEVLHPHLTRFLQDVSRTPG 3168
Query: 1164 -PF------CAERLRRTYANGVRAEPPTWLELQAVKSKKHIPIQVILATG--------ES 1208
PF C + L++T G R E P+ +EL+A+ + + Q+ L G ++
Sbjct: 3169 LPFQGIAKACEQNLQKTLRFGGRLELPSSIELRAMLAGRSSKRQLFLLPGGLERHLKIKT 3228
Query: 1209 LTVPVDSASTSREMC--MHIAHKQGLSDHLGFSLQVAVYDKFWSLGSGRDHMMDAIARCE 1266
TV +D E+C M + + ++++ F V + S R +++D + E
Sbjct: 3229 CTVALD---VVEEICAEMALTRPEAFNEYVIF--VVTNRGQHVCPLSRRAYILDVASEME 3283
Query: 1267 QMAQERGESQRQSPW--RIYFRKEFFTPWHDSREDPVSTELIYRQVLRGVWSGEYSFEKE 1324
Q+ R+ W + F E + H ++ P L+G++S +
Sbjct: 3284 QVDGGYMLWFRRVLWDQPLKFENELYVTMHYNQVLP--------DYLKGLFSSVPASRPS 3335
Query: 1325 EELVELLARHCYVQLGAS-----AESKAVQELLPSCIPHKLYRTKPPDRWASLVTAACAK 1379
E+L++ +++ +Q A + VQE +P+ +LYRT W +LV ++
Sbjct: 3336 EQLLQQVSKLASLQHRAKDHFYLPSVREVQEYIPA----QLYRTTAGSTWLNLV----SQ 3387
Query: 1380 APYTQKQVTPLAVREQVVDAARLQWPLLFSRLFEVITLSGPRLPKTQLILAVNWKGLCFL 1439
+ ++P R Q + P+ S F + + S +P ILA+N GL FL
Sbjct: 3388 HRQQTQALSPHQARAQFLGLLS-ALPMFGSSFFFIQSCSNIAVP-APCILAINHNGLNFL 3445
Query: 1440 D-QQEKMLLELSFPEVMGLATNR 1461
+ +++++ E+ T R
Sbjct: 3446 STETHELMVKFPLKEIQSTRTQR 3468
Score = 62.4 bits (150), Expect = 5e-09
Identities = 50/160 (31%), Positives = 66/160 (41%), Gaps = 17/160 (10%)
Query: 1648 PLRQPLLK---RVHANVDLWDIACQIFVAILRYMGDYPSRQAWPTLELTDQIFTLALQHP 1704
PLR PL + HA A IF ILR+MGD A + + I L P
Sbjct: 2069 PLRTPLTQLPAEHHAE------AVSIFKLILRFMGDPHLHGARENI-FGNYIVQKGLAVP 2121
Query: 1705 ALQDEVYCQILKQLTHNSNRHSEERGWQLLWLCTGLFPPSKGLLPHAQKFIDTRRGKLLA 1764
L+DE+ Q+ Q+ HN N H+ ERGW LL C F PS + KF+
Sbjct: 2122 ELRDEILAQLANQVWHNHNAHNAERGWLLLAACLSGFAPSPCFNKYLLKFVSDYGRNGFQ 2181
Query: 1765 PDCSRRIQKVL-------RTGPRKQPPHQVEVEAAEQNVS 1797
C R+ + + R PP Q+E A + S
Sbjct: 2182 AVCQHRLMQAMGRAQQQGSGAARTLPPTQLEWTATYEKAS 2221
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 599 bits (1545), Expect = e-171
Identities = 333/841 (39%), Positives = 497/841 (59%), Gaps = 46/841 (5%)
Query: 4 FRLGDHVWLEPPSTHKTGVAIGGIIKEAKPGKVLVEDDEGKEHWIRAEDFG--VLSPMHP 61
F G VWL H + G V+ D G+ + ++ MHP
Sbjct: 5 FTEGTRVWLRENGQH-----FPSTVNSCAEGIVVFRTDYGQVFTYKQSTITHQKVTAMHP 59
Query: 62 NSVQGVDDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQ-VLPLYTLEQVQ 120
+ +GVDDM L +L+ +++NL RY++++IYTY GSIL +VNP+Q + LY ++
Sbjct: 60 TNEEGVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATME 119
Query: 121 LYYSRHMGELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATISG 180
Y RH+GELPPH+FAIAN CY + + +QC +ISGESGAGKTE+TKLIL+FL+ IS
Sbjct: 120 QYSRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQ 179
Query: 181 QH---------SWIEQQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGAR 231
Q S +E+ +LE++PI+EAFGNAKT+ N+NSSRFGK++ + G I+G R
Sbjct: 180 QSLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGR 239
Query: 232 IEQFLLEKSRVCRQAPEERNYHIFYCMLMGVSAEDKQLLSLGTPSEYHYLTMGNCTSCEG 291
I +LLEK+RV RQ P ERNYHIFY +L G+ E+++ L TP YHYL C +
Sbjct: 240 IVDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPENYHYLNQSGCVEDKT 299
Query: 292 LNDAKDYAHIRSAMKILQFSDSESWDVIKLLAAILHLGNVGFMASVFENLDASDVMETPA 351
++D + + + +AM ++QFS E +V +LLA ILHLGN+ F+ + + V A
Sbjct: 300 ISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEFITA-----GGAQVSFKTA 354
Query: 352 FPTVMKLLEVQHQELRDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIV 411
+LL + +L D L + ++ +RGE + LN+ QA D RD+ +Y F W++
Sbjct: 355 LGRSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWVI 414
Query: 412 KKINAAIFTPPAQDPKNVRRAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFT 471
KKIN+ I ++IG+LDIFGFENFE N FEQ IN+ANE LQ++F +H+F+
Sbjct: 415 KKINSRI------KGNEDFKSIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFS 468
Query: 472 MEQEEYRSENISWDYIHYTDNRPTLDLLALKPMSIISLLDEESRFPQGTDLTMLQKLNSV 531
+EQ EY E + W+ I + DN LDL+ K + +++L++EES FPQ TD T+L+KL+S
Sbjct: 469 LEQLEYSREGLVWEDIDWIDNGECLDLIE-KKLGLLALINEESHFPQATDSTLLEKLHSQ 527
Query: 532 HANNKAFLQPKNIHDARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLRE 591
HANN +++P+ + FG+ H+AGEV Y G LEKNRD D+L L+ S+ F+ +
Sbjct: 528 HANNHFYVKPR-VAVNNFGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIYD 586
Query: 592 IFNLELAETKLGHGTIRQAKAGNHLFKSADSNKRPSTLGSQFKQSLDQLMKILTNCQPYF 651
+F E ++ T+ K ++RP T+ SQFK SL LM L++ P+F
Sbjct: 587 LF--EHVSSRNNQDTL----------KCGSKHRRP-TVSSQFKDSLHSLMATLSSSNPFF 633
Query: 652 IRCIKPNEYKKPLLFDRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPNA 711
+RCIKPN K P FD+ + L QLRYSGM+ETV IRK+G+ +R F++F +R+ VL+ N
Sbjct: 634 VRCIKPNMQKMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRN- 692
Query: 712 MRMQLQGKLRQMTLGITDVWLRTDKDWKAGKTKIFLRDHQDTLLEVQRSQVLDRAALSIQ 771
+ L +R + ++ ++ +W+ GKTK+FLR+ + LE +R + + AA+ I+
Sbjct: 693 --LALPEDVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIR 750
Query: 772 KVLRGYRYRKEFLRQRRAAVTLQAWWRGYCNRRNFKLILVGFERLQAIARSQPLARQYQA 831
+ G+ RK++ + V +Q +R + RR F + Q R Q R Y+
Sbjct: 751 AHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQ 810
Query: 832 M 832
+
Sbjct: 811 L 811
Score = 60.1 bits (144), Expect = 2e-08
Identities = 64/250 (25%), Positives = 104/250 (41%), Gaps = 22/250 (8%)
Query: 1102 LRPSLRDEIYCQICKQLSENFKTSSLAR--GWILLSLCLGC-FPPSERFMKYLL------ 1152
LRP LRDE+YCQ+ KQ ++ S+ W +L+ CL C F PS +KYL
Sbjct: 1599 LRP-LRDELYCQLIKQTNKVPHPGSVGNLYSWQILT-CLSCTFLPSRGILKYLKFHLKRI 1656
Query: 1153 --NFIGQGPATYGPFCAERLRRTYANGVRAEPPTWLELQAVKSKKHIPIQVILATGESLT 1210
F G Y F E L++T R P+ E++A+ ++ + V G S
Sbjct: 1657 REQFPGSEMEKYALFTYESLKKTKC---REFVPSRDEIEALIHRQEMTSTVYCHGGGSCK 1713
Query: 1211 VPVDSASTSREMCMHIAHKQGLSDHLGFSLQVAVYDKFWSLGSGRDHMMDAIARCEQMA- 1269
+ ++S +T+ E+ + + D R + D +A+ E++A
Sbjct: 1714 ITINSHTTAGEVVEKLIRGLAMEDSRNMFALFEYNGHVDKAIESRTVVADVLAKFEKLAA 1773
Query: 1270 -QERGESQRQSPWRIYFRKEFFTPWHDSREDPVSTELIYRQVLRGVWSGEYSFEKEEELV 1328
E G+ PW+ YF+ F + +D V ++ Q V G + +E V
Sbjct: 1774 TSEVGD----LPWKFYFKLYCFLDTDNVPKDSVEFAFMFEQAHEAVIHGHHPAPEENLQV 1829
Query: 1329 ELLARHCYVQ 1338
R Y+Q
Sbjct: 1830 LAALRLQYLQ 1839
Score = 44.7 bits (104), Expect = 0.001
Identities = 102/537 (18%), Positives = 193/537 (35%), Gaps = 99/537 (18%)
Query: 1638 RGHLWAYSCEPLRQPLLKRVHANVDL-----------WDIACQIFVAI--LRYMGDYPSR 1684
R + Y+ PL PLL + +++L D A +IF ++ L M D
Sbjct: 1529 RNPILRYTHHPLHSPLLPLPYGDINLNLLKDKGYTTLQDEAIKIFNSLQQLESMSD---- 1584
Query: 1685 QAWPTLELTDQIFTLALQHPALQDEVYCQILKQLTHNSNRHSEERG----WQLLWLCTGL 1740
+ + I L+DE+YCQ++KQ N H G WQ+L +
Sbjct: 1585 ----PIPIIQGILQTGHDLRPLRDELYCQLIKQT--NKVPHPGSVGNLYSWQILTCLSCT 1638
Query: 1741 FPPSKGLLP----HAQKFIDTRRGKLLAPDCSRRIQKVLRTGPRKQPPHQVEVEAAEQNV 1796
F PS+G+L H ++ + G + + + +T R+ P + E+EA
Sbjct: 1639 FLPSRGILKYLKFHLKRIREQFPGSEMEKYALFTYESLKKTKCREFVPSRDEIEALIHR- 1697
Query: 1797 SRICHKIYFPNDTSEMLEVVANTRVRDVCDSIATRLQLASWEGCSLFIKISDKVISQKEG 1856
+ +Y S + + ++T +V + + L + + + V
Sbjct: 1698 QEMTSTVYCHGGGSCKITINSHTTAGEVVEKLIRGLAMEDSRNMFALFEYNGHV------ 1751
Query: 1857 DFFFDSLREVSDWVKKNKPQKEGAPV-TLPYQVYFMRKLWLNISPGKDVNADTILHYHQE 1915
D +S V+D + K + + V LP++ YF +L+ + + + Q
Sbjct: 1752 DKAIESRTVVADVLAKFEKLAATSEVGDLPWKFYFKLYCFLDTDNVPKDSVEFAFMFEQA 1811
Query: 1916 LPKYLRGFHKCSREDAIHLAGLIYKAQFNNDRSQLASVP--------------------- 1954
+ G H E+ LA L + D + A++P
Sbjct: 1812 HEAVIHGHHPAPEENLQVLAALRLQ-YLQGDYTLHAAIPPLEEVYSLQRLKARISQSTKT 1870
Query: 1955 --------------------------KILRELVPENLTRLMSSEE----WKKSILLAYDK 1984
++R+ V E M +E + SI+ + K
Sbjct: 1871 FTPCERLEKRRTSFLEGTLRRSFRTGSVVRQKVEEEQMLDMWIKEEVSSARASIIDKWRK 1930
Query: 1985 HKDKTVEEAKVAFLKWICRWPTFGSAFFEVKQTSEPSYPDVILIAINRHGVLLIHPKTKD 2044
+ E+A ++ I WP +GS F+V + E +P + + ++ V +
Sbjct: 1931 FQGMNQEQAMAKYMALIKEWPGYGSTLFDV-ECKEGGFPQELWLGVSADAVSVYKRGEGR 1989
Query: 2045 LLTTYPFTKISSWSS--GSTYFHMALGSLGRGSRLLCETSLGYKMDDLLTSYVQQLL 2099
L + + I S+ + +TY + LL ETS + L+ +Y+ ++
Sbjct: 1990 PLEVFQYEHILSFGAPLANTYKIVV-----DERELLFETSEVVDVAKLMKAYISMIV 2041
>gi|215982794 myosin VA isoform 2 [Homo sapiens]
Length = 1828
Score = 572 bits (1474), Expect = e-162
Identities = 335/872 (38%), Positives = 501/872 (57%), Gaps = 35/872 (4%)
Query: 27 IIKEAKPGK--VLVEDDEGK--EHWIRAEDFGVLSPMHPNSVQGVDDMIRLGDLNEAGMV 82
++K+ KPG +L+ +EGK E+ + + + +P+ + G +D+ L L+E ++
Sbjct: 27 LLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGENDLTALSYLHEPAVL 86
Query: 83 HNLLIRYQQHK-IYTYTGSILVAVNPFQVLPLYTLEQVQLYYSRHMGELPPHVFAIANNC 141
HNL +R+ K IYTY G +LVA+NP++ LP+Y + + Y ++MG++ PH+FA+A
Sbjct: 87 HNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNMGDMDPHIFAVAEEA 146
Query: 142 YFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATISGQHSW--IEQQVLEANPILEAF 199
Y M R++R+Q I+SGESGAGKT + K +++ AT+SG S +E++VL +NPI+E+
Sbjct: 147 YKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASEANVEEKVLASNPIMESI 206
Query: 200 GNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKSRVCRQAPEERNYHIFYCML 259
GNAKT RNDNSSRFGKYI+I F+ I GA + +LLEKSRV QA EERNYHIFY +
Sbjct: 207 GNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLC 266
Query: 260 MGVSAEDKQLLSLGTPSEYHYLTMGNCTSCEGLNDAKDYAHIRSAMKILQFSDSESWDVI 319
+ ++L LG ++Y G EG++DAK+ AH R A +L S+S +
Sbjct: 267 ASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEMAHTRQACTLLGISESHQMGIF 326
Query: 320 KLLAAILHLGNVGFMASVFENLDASDVMETPAFPTV---MKLLEVQHQELRDCLIKHTIL 376
++LA ILHLGNVGF + DA P + L+ V ++E+ L +
Sbjct: 327 RILAGILHLGNVGFTSR-----DADSCTIPPKHEPLCIFCDLMGVDYEEMCHWLCHRKLA 381
Query: 377 IRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIFTPPAQDPKNVRRAIGLL 436
E + ++ QA + RDA K IY LF WIV +N A+ + Q IG+L
Sbjct: 382 TATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALHSAVKQ-----HSFIGVL 436
Query: 437 DIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYRSENISWDYIHYTDNRPTL 496
DI+GFE FE NSFEQ CIN+ANE LQQ F HVF +EQEEY E I W I + DN+P +
Sbjct: 437 DIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCI 496
Query: 497 DLLALKPMSIISLLDEESRFPQGTDLTMLQKLNSVHANNKAFLQPKNIHDARFGIAHFAG 556
+L+ K + I+ LLDEE + P+GTD T QKL + H N A + + + F I HFA
Sbjct: 497 NLIESK-LGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKPRLSNKAFIIQHFAD 555
Query: 557 EVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLREIFNLE------LAETKLGHGTIRQA 610
+V YQ EGFLEKN+D + + + ++ SSK K L E+F + + T G + +
Sbjct: 556 KVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISPTSATSSGRTPLTRT 615
Query: 611 KAGNHLFKSAD-SNKRPSTLGSQFKQSLDQLMKILTNCQPYFIRCIKPNEYKKPLLFDRE 669
A + + + T+G QF+ SL LM+ L P+++RCIKPN++K P FD +
Sbjct: 616 PAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEK 675
Query: 670 LCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPNAMRMQLQGKLRQMTLGITD 729
++QLR G++ET+ I +GFP R+T++EF R+ VL+ + + +Q + +
Sbjct: 676 RAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLM---KQKDVLSDRKQTCKNVLE 732
Query: 730 VWLRTDKDWKAGKTKIFLRDHQDTLLEVQRSQVLDRAALSIQKVLRGYRYRKEFLRQRRA 789
+ ++ GKTKIF R Q LE R+ L A + IQK +RG+ RK++LR R+A
Sbjct: 733 KLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKA 792
Query: 790 AVTLQAWWRGYCNRRNFKLI--LVGFERLQAIARSQPLARQYQAMRQRTVQLQALCRGYL 847
A+T+Q + RGY R K + +Q R + R+Y+ R T+ LQ+ RG+L
Sbjct: 793 AITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFL 852
Query: 848 VRQQVQ--AKRRAVVVIQAHARGMAARRNFQQ 877
R + + + V+IQ RG AR ++++
Sbjct: 853 ARNRYRKILREHKAVIIQKRVRGWLARTHYKR 884
>gi|215982791 myosin VA isoform 1 [Homo sapiens]
Length = 1855
Score = 572 bits (1474), Expect = e-162
Identities = 335/872 (38%), Positives = 501/872 (57%), Gaps = 35/872 (4%)
Query: 27 IIKEAKPGK--VLVEDDEGK--EHWIRAEDFGVLSPMHPNSVQGVDDMIRLGDLNEAGMV 82
++K+ KPG +L+ +EGK E+ + + + +P+ + G +D+ L L+E ++
Sbjct: 27 LLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGENDLTALSYLHEPAVL 86
Query: 83 HNLLIRYQQHK-IYTYTGSILVAVNPFQVLPLYTLEQVQLYYSRHMGELPPHVFAIANNC 141
HNL +R+ K IYTY G +LVA+NP++ LP+Y + + Y ++MG++ PH+FA+A
Sbjct: 87 HNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNMGDMDPHIFAVAEEA 146
Query: 142 YFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATISGQHSW--IEQQVLEANPILEAF 199
Y M R++R+Q I+SGESGAGKT + K +++ AT+SG S +E++VL +NPI+E+
Sbjct: 147 YKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASEANVEEKVLASNPIMESI 206
Query: 200 GNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKSRVCRQAPEERNYHIFYCML 259
GNAKT RNDNSSRFGKYI+I F+ I GA + +LLEKSRV QA EERNYHIFY +
Sbjct: 207 GNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLC 266
Query: 260 MGVSAEDKQLLSLGTPSEYHYLTMGNCTSCEGLNDAKDYAHIRSAMKILQFSDSESWDVI 319
+ ++L LG ++Y G EG++DAK+ AH R A +L S+S +
Sbjct: 267 ASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEMAHTRQACTLLGISESHQMGIF 326
Query: 320 KLLAAILHLGNVGFMASVFENLDASDVMETPAFPTV---MKLLEVQHQELRDCLIKHTIL 376
++LA ILHLGNVGF + DA P + L+ V ++E+ L +
Sbjct: 327 RILAGILHLGNVGFTSR-----DADSCTIPPKHEPLCIFCDLMGVDYEEMCHWLCHRKLA 381
Query: 377 IRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIFTPPAQDPKNVRRAIGLL 436
E + ++ QA + RDA K IY LF WIV +N A+ + Q IG+L
Sbjct: 382 TATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALHSAVKQ-----HSFIGVL 436
Query: 437 DIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYRSENISWDYIHYTDNRPTL 496
DI+GFE FE NSFEQ CIN+ANE LQQ F HVF +EQEEY E I W I + DN+P +
Sbjct: 437 DIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCI 496
Query: 497 DLLALKPMSIISLLDEESRFPQGTDLTMLQKLNSVHANNKAFLQPKNIHDARFGIAHFAG 556
+L+ K + I+ LLDEE + P+GTD T QKL + H N A + + + F I HFA
Sbjct: 497 NLIESK-LGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKPRLSNKAFIIQHFAD 555
Query: 557 EVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLREIFNLE------LAETKLGHGTIRQA 610
+V YQ EGFLEKN+D + + + ++ SSK K L E+F + + T G + +
Sbjct: 556 KVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISPTSATSSGRTPLTRT 615
Query: 611 KAGNHLFKSAD-SNKRPSTLGSQFKQSLDQLMKILTNCQPYFIRCIKPNEYKKPLLFDRE 669
A + + + T+G QF+ SL LM+ L P+++RCIKPN++K P FD +
Sbjct: 616 PAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEK 675
Query: 670 LCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPNAMRMQLQGKLRQMTLGITD 729
++QLR G++ET+ I +GFP R+T++EF R+ VL+ + + +Q + +
Sbjct: 676 RAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLM---KQKDVLSDRKQTCKNVLE 732
Query: 730 VWLRTDKDWKAGKTKIFLRDHQDTLLEVQRSQVLDRAALSIQKVLRGYRYRKEFLRQRRA 789
+ ++ GKTKIF R Q LE R+ L A + IQK +RG+ RK++LR R+A
Sbjct: 733 KLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKA 792
Query: 790 AVTLQAWWRGYCNRRNFKLI--LVGFERLQAIARSQPLARQYQAMRQRTVQLQALCRGYL 847
A+T+Q + RGY R K + +Q R + R+Y+ R T+ LQ+ RG+L
Sbjct: 793 AITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFL 852
Query: 848 VRQQVQ--AKRRAVVVIQAHARGMAARRNFQQ 877
R + + + V+IQ RG AR ++++
Sbjct: 853 ARNRYRKILREHKAVIIQKRVRGWLARTHYKR 884
>gi|153945715 myosin VC [Homo sapiens]
Length = 1742
Score = 552 bits (1423), Expect = e-156
Identities = 336/888 (37%), Positives = 498/888 (56%), Gaps = 39/888 (4%)
Query: 35 KVLVEDDEGKEHWIRAEDFGVLSPMHPNSVQGVDDMIRLGDLNEAGMVHNLLIRYQQHK- 93
++L+ED ++ + E L +P+ + G +D+ L L+E ++HNL IR+ + K
Sbjct: 39 RLLLEDGTELDYSVNPESLPPLR--NPDILVGENDLTALSYLHEPAVLHNLRIRFAESKL 96
Query: 94 IYTYTGSILVAVNPFQVLPLYTLEQVQLYYSRHMGELPPHVFAIANNCYFSMKRNKRDQC 153
IYTY+G ILVA+NP++ LP+Y + Y ++MG++ PH+FA+A Y M RN R+Q
Sbjct: 97 IYTYSGIILVAMNPYKQLPIYGDAIIHAYSGQNMGDMDPHIFAVAEEAYKQMARNNRNQS 156
Query: 154 CIISGESGAGKTETTKLILQFLATIS--GQHSWIEQQVLEANPILEAFGNAKTIRNDNSS 211
I+SGESGAGKT + + +++ AT+S G ++ +E +VL +NPI EA GNAKT RNDNSS
Sbjct: 157 IIVSGESGAGKTVSARYAMRYFATVSKSGSNAHVEDKVLASNPITEAVGNAKTTRNDNSS 216
Query: 212 RFGKYIDIYFNPSGVIEGARIEQFLLEKSRVCRQAPEERNYHIFYCMLMGVSAEDKQLLS 271
RFGKY +I F+ I GA + +LLEKSRV Q+ ERNYHIFY + + + L
Sbjct: 217 RFGKYTEISFDEQNQIIGANMSTYLLEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLK 276
Query: 272 LGTPSEYHYLTMGNCTSCEGLNDAKDYAHIRSAMKILQFSDSESWDVIKLLAAILHLGNV 331
LG+ E++Y MG T EG+ND + + +L F + DV K+LAAILHLGNV
Sbjct: 277 LGSAEEFNYTRMGGNTVIEGVNDRAEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNV 336
Query: 332 GFMASVFENLDASDVMETPAFPTVMKLLEVQHQELRDCLIKHTILIRGEFVTRSLNIAQA 391
A E S+ + +LL ++ + L I+ E V + + QA
Sbjct: 337 QITAVGNERSSVSE--DDSHLKVFCELLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQA 394
Query: 392 ADRRDAFVKGIYGHLFLWIVKKINAAIFTPPAQDPKNVRRAIGLLDIFGFENFENNSFEQ 451
+ RDA K IY HLF +IV++IN A+ Q IG+LDI+GFE F+ NSFEQ
Sbjct: 395 VNARDALAKKIYAHLFDFIVERINQAL-----QFSGKQHTFIGVLDIYGFETFDVNSFEQ 449
Query: 452 LCINFANEHLQQFFVQHVFTMEQEEYRSENISWDYIHYTDNRPTLDLLALKPMSIISLLD 511
CIN+ANE LQQ F HVF +EQEEY E+I W I + DN+P +DL+ K M I+ LLD
Sbjct: 450 FCINYANEKLQQQFNMHVFKLEQEEYMKEDIPWTLIDFYDNQPVIDLIEAK-MGILELLD 508
Query: 512 EESRFPQGTDLTMLQKLNSVHANNKAFLQPKNIHDARFGIAHFAGEVYYQAEGFLEKNRD 571
EE P GTD LQKL + N + + + F I HFA +V Y+ EGFLEKNRD
Sbjct: 509 EECLLPHGTDENWLQKLYNNFVNRNPLFEKPRMSNTSFVIQHFADKVEYKCEGFLEKNRD 568
Query: 572 VLSTDILTLVYSSKNKFLREIFNLELAETKLGHGTIRQAKAGNHLFKSADSNKRPSTLGS 631
+ ++ ++ +SK F E G++ K+ + K + R +T+GS
Sbjct: 569 TVYDMLVEILRASKFHLCANFFQ-ENPTPPSPFGSMITVKSAKQVIKPNSKHFR-TTVGS 626
Query: 632 QFKQSLDQLMKILTNCQPYFIRCIKPNEYKKPLLFDRELCLRQLRYSGMMETVHIRKSGF 691
+F+ SL LM+ L P+++RCIKPN+ K P FD + ++QLR G++ET+ I +
Sbjct: 627 KFRSSLYLLMETLNATTPHYVRCIKPNDEKLPFEFDSKRIVQQLRACGVLETIRISAQSY 686
Query: 692 PIRYTFEEFSQRFGVLLPNAMRMQLQGKLRQMTLGITDVWLRTDKDWKAGKTKIFLRDHQ 751
P R+T+ EF R+G+L+ + K +++ + ++ ++ GKTKIF R Q
Sbjct: 687 PSRWTYIEFYSRYGILM-TKQELSFSDK-KEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQ 744
Query: 752 DTLLEVQRSQVLDRAALSIQKVLRGYRYRKEFLRQRRAAVTLQAWWRGYCNRRNFKLILV 811
LE R L ++ + +QK +RG+ RK+FLR+RRAA+ +Q ++RG R
Sbjct: 745 VAYLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLRERRAALIIQQYFRGQQTVR------- 797
Query: 812 GFERLQAIARSQPLARQYQAMRQRTVQLQALCRGYLVRQQVQAKRRAVVVIQAHARGMAA 871
+ + A+A + A + +Q CRGYLVR Q R A + +QA++RG A
Sbjct: 798 --KAITAVALKEAWA---------AIIIQKHCRGYLVRSLYQLIRMATITMQAYSRGFLA 846
Query: 872 RRNFQQRKANAPLVIPAEGQKSQGALPAKKR-RSIYDTVTDTEMVEKV 918
RR +++ VI QK A A++R +SI V + ++ +V
Sbjct: 847 RRRYRKMLEEHKAVIL---QKYARAWLARRRFQSIRRFVLNIQLTYRV 891
>gi|122937345 myosin VB [Homo sapiens]
Length = 1848
Score = 540 bits (1390), Expect = e-153
Identities = 327/891 (36%), Positives = 509/891 (57%), Gaps = 27/891 (3%)
Query: 10 VWLEPPSTHKTGVAIGGIIKEA-KPGKVLVEDDEGKEHWIRAEDFGVLSPMHPNSVQGVD 68
VW+ P + KE K ++ +ED+ E+ I + + +P+ + G +
Sbjct: 13 VWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLPFLRNPDILVGEN 72
Query: 69 DMIRLGDLNEAGMVHNLLIRY-QQHKIYTYTGSILVAVNPFQVLPLYTLEQVQLYYSRHM 127
D+ L L+E ++HNL +R+ + + IYTY G +LVA+NP++ LP+Y + + Y ++M
Sbjct: 73 DLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQNM 132
Query: 128 GELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATISGQHSW--I 185
G++ PH+FA+A Y M R++++Q I+SGESGAGKT + K +++ AT+ G S I
Sbjct: 133 GDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASETNI 192
Query: 186 EQQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKSRVCRQ 245
E++VL ++PI+EA GNAKT RNDNSSRFGKYI I F+ I GA + +LLEKSRV Q
Sbjct: 193 EEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYLLEKSRVVFQ 252
Query: 246 APEERNYHIFYCMLMGVSAEDKQLLSLGTPSEYHYLTMGNCTSCEGLNDAKDYAHIRSAM 305
A +ERNYHIFY + + + L+L + ++ Y + G TS EG++DA+D+ R A
Sbjct: 253 ADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVDDAEDFEKTRQAF 312
Query: 306 KILQFSDSESWDVIKLLAAILHLGNVGFMASVFENLDASDVMETPAF-PTVMKLLEVQHQ 364
+L +S + K++A+ILHLG+V A + D+ + + +LL V+H
Sbjct: 313 TLLGVKESHQMSIFKIIASILHLGSVAIQAE--RDGDSCSISPQDVYLSNFCRLLGVEHS 370
Query: 365 ELRDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIFTPPAQ 424
++ L ++ E +++++ Q + R+A K IY LF WIV+ IN A+ T Q
Sbjct: 371 QMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHINKALHTSLKQ 430
Query: 425 DPKNVRRAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYRSENISW 484
IG+LDI+GFE FE NSFEQ CIN+ANE LQQ F HVF +EQEEY E I W
Sbjct: 431 -----HSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQIPW 485
Query: 485 DYIHYTDNRPTLDLLALKPMSIISLLDEESRFPQGTDLTMLQKLNSVHANNKAFLQPKNI 544
I + DN+P +DL+ K + I+ LLDEE + P+GTD QKL H++++ F +P+ +
Sbjct: 486 TLIDFYDNQPCIDLIEAK-LGILDLLDEECKVPKGTDQNWAQKLYDRHSSSQHFQKPR-M 543
Query: 545 HDARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLREIFNLE---LAETK 601
+ F I HFA +V Y ++GFLEKNRD + + + ++ +SK + ++F+ + + T
Sbjct: 544 SNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKDPVPATT 603
Query: 602 LGHGTIRQAKAGNHLFKSADSNK-RPSTLGSQFKQSLDQLMKILTNCQPYFIRCIKPNEY 660
G G+ + + SNK T+G QF+ SL LM+ L P+++RCIKPN+
Sbjct: 604 PGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATTPHYVRCIKPNDE 663
Query: 661 KKPLLFDRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPNAMRMQLQGKL 720
K P FD + ++QLR G++ET+ I +G+P R+ + +F R+ VL+ R
Sbjct: 664 KLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVKK--RELANTDK 721
Query: 721 RQMTLGITDVWLRTDKDWKAGKTKIFLRDHQDTLLEVQRSQVLDRAALSIQKVLRGYRYR 780
+ + + + ++ ++ G+TKIF R Q LE R+ A + IQK +RG+ +
Sbjct: 722 KAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRGWLQK 781
Query: 781 KEFLRQRRAAVTLQAWWRGYCNRRNFKLI--LVGFERLQAIARSQPLARQYQAMRQRTVQ 838
++ R + A +TLQ + RG+ RR + + + LQ R Q + YQ +R+ V
Sbjct: 782 VKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRARQAYQRVRRAAVV 841
Query: 839 LQALCRGYLVR---QQVQAKRRAVVVIQAHARGMAARRNFQQRKANAPLVI 886
+QA R VR +QV + +A IQ H RG ARR+F QR +A +VI
Sbjct: 842 IQAFTRAMFVRRTYRQVLMEHKA-TTIQKHVRGWMARRHF-QRLRDAAIVI 890
Score = 38.9 bits (89), Expect = 0.054
Identities = 27/82 (32%), Positives = 43/82 (52%), Gaps = 6/82 (7%)
Query: 759 RSQVLDRAALSIQKVLRGYRYRKEFLRQRRAAVTLQAWWRGYCNRRNFKLILVGFERLQA 818
R +++ A +IQK +RG+ R+ F R R AA+ +Q +R RR K + R++A
Sbjct: 856 RQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRELKAL-----RIEA 910
Query: 819 IARSQPLARQYQAMRQRTVQLQ 840
++ L R M + VQLQ
Sbjct: 911 -RSAEHLKRLNVGMENKVVQLQ 931
>gi|134288892 myosin IIIB isoform 2 [Homo sapiens]
Length = 1341
Score = 520 bits (1338), Expect = e-147
Identities = 307/784 (39%), Positives = 457/784 (58%), Gaps = 61/784 (7%)
Query: 68 DDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQVQLYYSRHM 127
DD++ L L+E ++H L RY IYTY G IL+A+NPFQ L +Y+ + +LY+
Sbjct: 346 DDLVNLEVLDEDTIIHQLQKRYADLLIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKR 405
Query: 128 GELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATIS-GQHSWIE 186
PPH+FA A+ Y M +DQC +ISGESG+GKTE+ LI+Q L + + +
Sbjct: 406 ASNPPHIFASADAAYQCMVTLSKDQCIVISGESGSGKTESAHLIVQHLTFLGKANNQTLR 465
Query: 187 QQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKSRVCRQA 246
+++L+ N ++EAFGN+ T NDNSSRFGKY+++ F P+GV+ GARI ++LLEKSRV +QA
Sbjct: 466 EKILQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTPTGVVMGARISEYLLEKSRVIKQA 525
Query: 247 PEERNYHIFYCMLMGVSAEDKQLLSLGTPSEY--HYLT------MGNCTSCEGLNDAKDY 298
E+N+HIFY + G+ + K+L P E Y+ M + TS E + +
Sbjct: 526 AREKNFHIFYYIYAGLHHQ-KKLSDFRLPEEKPPRYIADETGRVMHDITSKESYR--RQF 582
Query: 299 AHIRSAMKILQFSDSESWDVIKLLAAILHLGNVGFMA-SVFENLDASDVMETPAFPTVMK 357
I+ +I+ F+D E V ++LA IL++GN+ F A S D S+V A
Sbjct: 583 EAIQHCFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQHQTDKSEVPNAEALQNAAS 642
Query: 358 LLEVQHQELRDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAA 417
+L + +EL++ L H ++ RGE + R+ + +AAD RDA K +YG LF WIV +IN
Sbjct: 643 VLCISPEELQEALTSHCVVTRGETIIRANTVDRAADVRDAMSKALYGRLFSWIVNRINTL 702
Query: 418 IFTPPAQDPKNVRRA-----IGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTM 472
+ Q +N+ A +G+LDIFGFENF+ NSFEQLCIN ANE +Q +F QHVF +
Sbjct: 703 L-----QPDENICSAGGGMNVGILDIFGFENFQRNSFEQLCINIANEQIQYYFNQHVFAL 757
Query: 473 EQEEYRSENISWDYIHYTDNRPTLDLLALKPMSIISLLDEESRFPQGTDLTMLQKLNSVH 532
EQ EY++E I + Y DNRP LD+ KP+ +++LLDEESRFPQ TD T++ K +
Sbjct: 758 EQMEYQNEGIDAVPVEYEDNRPLLDMFLQKPLGLLALLDEESRFPQATDQTLVDKFED-N 816
Query: 533 ANNKAFLQPKNIHDARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLREI 592
K F +PK + + FGI H+AG+V Y A G LEKNRD L D++ ++ +S+N L+++
Sbjct: 817 LRCKYFWRPKGV-ELCFGIQHYAGKVLYDASGVLEKNRDTLPADVVVVLRTSENMLLQQL 875
Query: 593 FNLELAETKLGHGTIRQAKAGNHLFKSA-----------------------DSNKRPSTL 629
F++ L +T G + Q +A + S+ +N + T+
Sbjct: 876 FSIPLTKT----GNLAQTRARITVASSSLPPHFSAGKAKVDTLEVIRHPEETTNMKRQTV 931
Query: 630 GSQFKQSLDQLMKILTNCQPYFIRCIKPNEYKKPLLFDRELCLRQLRYSGMMETVHIRKS 689
S F+ SL L+ + QP+F+RCIKPN+ ++ L F RE L QLR +G++ETV IR+
Sbjct: 932 ASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREALQFSRERVLAQLRSTGILETVSIRRQ 991
Query: 690 GFPIRYTFEEFSQRFGVLLPNAMRMQLQGKLRQMTLGITDVWLRTDKDWKAGKTKIFLRD 749
G+ R FEEF +R+ L A + L K + + I + R D W GKTK+FL+
Sbjct: 992 GYSHRILFEEFVKRYYYLAFTAHQTPLASK--ESCVAILEK-SRLD-HWVLGKTKVFLKY 1047
Query: 750 HQDTLLEVQRSQVLDRAALSIQKVLRGY----RYRKEFLRQRRAAVTLQAWWRGYCNRRN 805
+ L + +V+ R + +Q +G+ RY+K ++ + A+ +Q+ WRGY RR
Sbjct: 1048 YHVEQLNLLLREVIGRVVV-LQAYTKGWLGARRYKKVREKREKGAIAIQSAWRGYDARRK 1106
Query: 806 FKLI 809
FK I
Sbjct: 1107 FKKI 1110
>gi|124494247 myosin IC isoform b [Homo sapiens]
Length = 1044
Score = 514 bits (1324), Expect = e-145
Identities = 290/759 (38%), Positives = 437/759 (57%), Gaps = 50/759 (6%)
Query: 66 GVDDMIRLGDL-NEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQVQLYYS 124
GV D + L + +EA + NL R++++ IYTY G +LV+VNP++ L +Y+ + ++ Y
Sbjct: 28 GVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRG 87
Query: 125 RHMGELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLA---TISGQ 181
E+PPH+FA+A+ Y +++ +RDQ +ISGESGAGKTE TK +LQF A +
Sbjct: 88 VSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPER 147
Query: 182 HSWIEQQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKSR 241
+ ++L++NP+LEAFGNAKT+RNDNSSRFGKY+D+ F+ G G I +LLEKSR
Sbjct: 148 GGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSR 207
Query: 242 VCRQAPEERNYHIFYCMLMGVSAEDKQLLSL-GTPSEYHYLTMGNCTSCEGLNDAKDYAH 300
V Q ERN+HIFY +L G E + L L P Y YL G C +ND D+
Sbjct: 208 VVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWKV 267
Query: 301 IRSAMKILQFSDSESWDVIKLLAAILHLGNVGFMASVFENLDASDVMETPAFPTVMKLLE 360
+R A+ ++ F++ E D++ ++A++LHLGN+ F A+ N + V + +LL
Sbjct: 268 VRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESN---AQVTTENQLKYLTRLLS 324
Query: 361 VQHQELRDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIFT 420
V+ LR+ L I+ +GE + LN+ QAA RDA K +Y F W+V KIN ++ +
Sbjct: 325 VEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSLAS 384
Query: 421 PPAQDPK-NVRRAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYRS 479
+ P +GLLDI+GFE F++NSFEQ CIN+ NE LQQ F++ EQEEY +
Sbjct: 385 KDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEA 444
Query: 480 ENISWDYIHYTDNRPTLDLLALKPMSIISLLDEESRFP-QGTDLTMLQKLNSVHANNKAF 538
E I+W+ + Y +N+ DL+ K IIS+LDEE P + TDLT L+KL ++ F
Sbjct: 445 EGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKHHPHF 504
Query: 539 L--------QPKNIHDARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLR 590
L K++ F + H+AGEV Y GFL+KN D+L ++ + SSKN +
Sbjct: 505 LTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNPIMS 564
Query: 591 EIFNLELAETKLGHGTIRQAKAGNHLFKSADSNKRPSTLGSQFKQSLDQLMKILTNCQPY 650
+ F+ K KRP T+ +QFK SL QL++IL + +P
Sbjct: 565 QCFDRSELSDK----------------------KRPETVATQFKMSLLQLVEILQSKEPA 602
Query: 651 FIRCIKPNEYKKPLLFDRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPN 710
++RCIKPN+ K+P FD L Q++Y G++E + +R++GF R +E F QR+ L P
Sbjct: 603 YVRCIKPNDAKQPGRFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPE 662
Query: 711 AMRMQLQGKLRQMTLGITDVWLRTDKDWKAGKTKIFLRDHQ-----DTLLEVQRSQVLDR 765
+ + + + + + ++K G+TKIF+R + + LEV+R +
Sbjct: 663 TWPTWAGRPQDGVAVLVRHLGYKPE-EYKMGRTKIFIRFPKTLFATEDALEVRRQSL--- 718
Query: 766 AALSIQKVLRGYRYRKEFLRQRRAAVTLQAWWRGYCNRR 804
A IQ RG+ +R++FLR +R+A+ +Q+WWRG RR
Sbjct: 719 -ATKIQAAWRGFHWRQKFLRVKRSAICIQSWWRGTLGRR 756
>gi|124494238 myosin IC isoform a [Homo sapiens]
Length = 1063
Score = 514 bits (1324), Expect = e-145
Identities = 290/759 (38%), Positives = 437/759 (57%), Gaps = 50/759 (6%)
Query: 66 GVDDMIRLGDL-NEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQVQLYYS 124
GV D + L + +EA + NL R++++ IYTY G +LV+VNP++ L +Y+ + ++ Y
Sbjct: 47 GVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRG 106
Query: 125 RHMGELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLA---TISGQ 181
E+PPH+FA+A+ Y +++ +RDQ +ISGESGAGKTE TK +LQF A +
Sbjct: 107 VSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPER 166
Query: 182 HSWIEQQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKSR 241
+ ++L++NP+LEAFGNAKT+RNDNSSRFGKY+D+ F+ G G I +LLEKSR
Sbjct: 167 GGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSR 226
Query: 242 VCRQAPEERNYHIFYCMLMGVSAEDKQLLSL-GTPSEYHYLTMGNCTSCEGLNDAKDYAH 300
V Q ERN+HIFY +L G E + L L P Y YL G C +ND D+
Sbjct: 227 VVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWKV 286
Query: 301 IRSAMKILQFSDSESWDVIKLLAAILHLGNVGFMASVFENLDASDVMETPAFPTVMKLLE 360
+R A+ ++ F++ E D++ ++A++LHLGN+ F A+ N + V + +LL
Sbjct: 287 VRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESN---AQVTTENQLKYLTRLLS 343
Query: 361 VQHQELRDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIFT 420
V+ LR+ L I+ +GE + LN+ QAA RDA K +Y F W+V KIN ++ +
Sbjct: 344 VEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSLAS 403
Query: 421 PPAQDPK-NVRRAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYRS 479
+ P +GLLDI+GFE F++NSFEQ CIN+ NE LQQ F++ EQEEY +
Sbjct: 404 KDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEA 463
Query: 480 ENISWDYIHYTDNRPTLDLLALKPMSIISLLDEESRFP-QGTDLTMLQKLNSVHANNKAF 538
E I+W+ + Y +N+ DL+ K IIS+LDEE P + TDLT L+KL ++ F
Sbjct: 464 EGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKHHPHF 523
Query: 539 L--------QPKNIHDARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLR 590
L K++ F + H+AGEV Y GFL+KN D+L ++ + SSKN +
Sbjct: 524 LTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNPIMS 583
Query: 591 EIFNLELAETKLGHGTIRQAKAGNHLFKSADSNKRPSTLGSQFKQSLDQLMKILTNCQPY 650
+ F+ K KRP T+ +QFK SL QL++IL + +P
Sbjct: 584 QCFDRSELSDK----------------------KRPETVATQFKMSLLQLVEILQSKEPA 621
Query: 651 FIRCIKPNEYKKPLLFDRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPN 710
++RCIKPN+ K+P FD L Q++Y G++E + +R++GF R +E F QR+ L P
Sbjct: 622 YVRCIKPNDAKQPGRFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPE 681
Query: 711 AMRMQLQGKLRQMTLGITDVWLRTDKDWKAGKTKIFLRDHQ-----DTLLEVQRSQVLDR 765
+ + + + + + ++K G+TKIF+R + + LEV+R +
Sbjct: 682 TWPTWAGRPQDGVAVLVRHLGYKPE-EYKMGRTKIFIRFPKTLFATEDALEVRRQSL--- 737
Query: 766 AALSIQKVLRGYRYRKEFLRQRRAAVTLQAWWRGYCNRR 804
A IQ RG+ +R++FLR +R+A+ +Q+WWRG RR
Sbjct: 738 -ATKIQAAWRGFHWRQKFLRVKRSAICIQSWWRGTLGRR 775
>gi|124494240 myosin IC isoform c [Homo sapiens]
Length = 1028
Score = 514 bits (1324), Expect = e-145
Identities = 290/759 (38%), Positives = 437/759 (57%), Gaps = 50/759 (6%)
Query: 66 GVDDMIRLGDL-NEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQVQLYYS 124
GV D + L + +EA + NL R++++ IYTY G +LV+VNP++ L +Y+ + ++ Y
Sbjct: 12 GVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRG 71
Query: 125 RHMGELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLA---TISGQ 181
E+PPH+FA+A+ Y +++ +RDQ +ISGESGAGKTE TK +LQF A +
Sbjct: 72 VSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPER 131
Query: 182 HSWIEQQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKSR 241
+ ++L++NP+LEAFGNAKT+RNDNSSRFGKY+D+ F+ G G I +LLEKSR
Sbjct: 132 GGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSR 191
Query: 242 VCRQAPEERNYHIFYCMLMGVSAEDKQLLSL-GTPSEYHYLTMGNCTSCEGLNDAKDYAH 300
V Q ERN+HIFY +L G E + L L P Y YL G C +ND D+
Sbjct: 192 VVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWKV 251
Query: 301 IRSAMKILQFSDSESWDVIKLLAAILHLGNVGFMASVFENLDASDVMETPAFPTVMKLLE 360
+R A+ ++ F++ E D++ ++A++LHLGN+ F A+ N + V + +LL
Sbjct: 252 VRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESN---AQVTTENQLKYLTRLLS 308
Query: 361 VQHQELRDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIFT 420
V+ LR+ L I+ +GE + LN+ QAA RDA K +Y F W+V KIN ++ +
Sbjct: 309 VEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSLAS 368
Query: 421 PPAQDPK-NVRRAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYRS 479
+ P +GLLDI+GFE F++NSFEQ CIN+ NE LQQ F++ EQEEY +
Sbjct: 369 KDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEA 428
Query: 480 ENISWDYIHYTDNRPTLDLLALKPMSIISLLDEESRFP-QGTDLTMLQKLNSVHANNKAF 538
E I+W+ + Y +N+ DL+ K IIS+LDEE P + TDLT L+KL ++ F
Sbjct: 429 EGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKHHPHF 488
Query: 539 L--------QPKNIHDARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLR 590
L K++ F + H+AGEV Y GFL+KN D+L ++ + SSKN +
Sbjct: 489 LTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNPIMS 548
Query: 591 EIFNLELAETKLGHGTIRQAKAGNHLFKSADSNKRPSTLGSQFKQSLDQLMKILTNCQPY 650
+ F+ K KRP T+ +QFK SL QL++IL + +P
Sbjct: 549 QCFDRSELSDK----------------------KRPETVATQFKMSLLQLVEILQSKEPA 586
Query: 651 FIRCIKPNEYKKPLLFDRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPN 710
++RCIKPN+ K+P FD L Q++Y G++E + +R++GF R +E F QR+ L P
Sbjct: 587 YVRCIKPNDAKQPGRFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPE 646
Query: 711 AMRMQLQGKLRQMTLGITDVWLRTDKDWKAGKTKIFLRDHQ-----DTLLEVQRSQVLDR 765
+ + + + + + ++K G+TKIF+R + + LEV+R +
Sbjct: 647 TWPTWAGRPQDGVAVLVRHLGYKPE-EYKMGRTKIFIRFPKTLFATEDALEVRRQSL--- 702
Query: 766 AALSIQKVLRGYRYRKEFLRQRRAAVTLQAWWRGYCNRR 804
A IQ RG+ +R++FLR +R+A+ +Q+WWRG RR
Sbjct: 703 -ATKIQAAWRGFHWRQKFLRVKRSAICIQSWWRGTLGRR 740
>gi|194328685 myosin IB isoform 1 [Homo sapiens]
Length = 1136
Score = 503 bits (1294), Expect = e-141
Identities = 303/840 (36%), Positives = 470/840 (55%), Gaps = 72/840 (8%)
Query: 66 GVDDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQVQLYYSR 125
GV DM+ L LNE ++NL R+ +IYTY GS++++VNP++ LP+Y+ E+V+ Y +R
Sbjct: 16 GVGDMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYRNR 75
Query: 126 HMGELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATISGQHSWI 185
+ EL PH+FA+++ Y S++ +DQC +I+GESGAGKTE +KL++ ++A + G+ + +
Sbjct: 76 NFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEV 135
Query: 186 EQ---QVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKSRV 242
Q Q+L++NP+LEAFGNAKT+RNDNSSRFGKY+DI F+ G G I +LLEKSRV
Sbjct: 136 NQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRV 195
Query: 243 CRQAPEERNYHIFYCMLMGVSAEDKQLLSLGTP-SEYHYLTMGNCTSCEGLNDAKDYAHI 301
+Q ERN+H+FY +L G S E L L S Y+YL++ + G++DA ++ +
Sbjct: 196 VKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSL-DSAKVNGVDDAANFRTV 254
Query: 302 RSAMKILQFSDSESWDVIKLLAAILHLGNVGFM-ASVFENLDASDVMETPAFPTVMKLLE 360
R+AM+I+ F D E+ V+ ++AA+L LGN+ F S LD S + + + +L
Sbjct: 255 RNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELTG 314
Query: 361 VQHQELRDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIFT 420
+ L T+ + E V+ +LN+AQA RDA K +Y LF W+V +IN +I
Sbjct: 315 IDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESI-- 372
Query: 421 PPAQDPKNVRRAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYRSE 480
K ++ +G+LDI+GFE FE+NSFEQ IN+ NE LQQ F++ EQEEY E
Sbjct: 373 --KAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIRE 430
Query: 481 NISWDYIHYTDNRPTLDLLALKPMSIISLLDEESRFP-QGTDLTMLQKLNSVHANNK--- 536
+I W +I Y +N DL+ I+++LDEE P TD T L+KLN V A ++
Sbjct: 431 DIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHFE 490
Query: 537 -------AFLQPKNIHDARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFL 589
FL ++ + F I H+AG+V YQ EGF++KN D+L D+ ++ + + +
Sbjct: 491 SRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKASHALI 550
Query: 590 REIFNLELAETKLGHGTIRQAKAGNHLFKSADSNKRPSTLGSQFKQSLDQLMKILTNCQP 649
+ +F GN + + KRP T GSQFK S+ LMK L P
Sbjct: 551 KSLF-----------------PEGN---PAKINLKRPPTAGSQFKASVATLMKNLQTKNP 590
Query: 650 YFIRCIKPNEYKKPLLFDRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLP 709
+IRCIKPN+ K +F+ L Q+RY G++E V +R++G+ R +E +R+ +L
Sbjct: 591 NYIRCIKPNDKKAAHIFNEALVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCK 650
Query: 710 NAMRMQLQGKLRQMTLGITDVWLRTDKDWKAGKTKIFLRDHQDTL-LEVQRSQVLDRAAL 768
+G R + + +++ G++KIF+R+ + LE R Q L+ A
Sbjct: 651 QTW-PHWKGPARSGVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLAT 709
Query: 769 SIQKVLRGYRYRKEFLRQRRAAVTLQAWWRGYCNRRNFKLILVGFERLQAIARSQPLARQ 828
IQK+ RG++ R FL +++ + + AW+R Y + ++
Sbjct: 710 LIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQ-----------------------KR 746
Query: 829 YQAMRQRTVQLQALCRGY----LVRQQVQAKR--RAVVVIQAHARGMAARRNFQQRKANA 882
YQ + + +Q+ RG+ ++R+ KR AV I A+ G ARR ++ K A
Sbjct: 747 YQQTKSSALVIQSYIRGWKARKILRELKHQKRCKEAVTTIAAYWHGTQARRELRRLKEEA 806
>gi|240120050 myosin IB isoform 1 [Homo sapiens]
Length = 1136
Score = 503 bits (1294), Expect = e-141
Identities = 303/840 (36%), Positives = 470/840 (55%), Gaps = 72/840 (8%)
Query: 66 GVDDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQVQLYYSR 125
GV DM+ L LNE ++NL R+ +IYTY GS++++VNP++ LP+Y+ E+V+ Y +R
Sbjct: 16 GVGDMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYRNR 75
Query: 126 HMGELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATISGQHSWI 185
+ EL PH+FA+++ Y S++ +DQC +I+GESGAGKTE +KL++ ++A + G+ + +
Sbjct: 76 NFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEV 135
Query: 186 EQ---QVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKSRV 242
Q Q+L++NP+LEAFGNAKT+RNDNSSRFGKY+DI F+ G G I +LLEKSRV
Sbjct: 136 NQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRV 195
Query: 243 CRQAPEERNYHIFYCMLMGVSAEDKQLLSLGTP-SEYHYLTMGNCTSCEGLNDAKDYAHI 301
+Q ERN+H+FY +L G S E L L S Y+YL++ + G++DA ++ +
Sbjct: 196 VKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSL-DSAKVNGVDDAANFRTV 254
Query: 302 RSAMKILQFSDSESWDVIKLLAAILHLGNVGFM-ASVFENLDASDVMETPAFPTVMKLLE 360
R+AM+I+ F D E+ V+ ++AA+L LGN+ F S LD S + + + +L
Sbjct: 255 RNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELTG 314
Query: 361 VQHQELRDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIFT 420
+ L T+ + E V+ +LN+AQA RDA K +Y LF W+V +IN +I
Sbjct: 315 IDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESI-- 372
Query: 421 PPAQDPKNVRRAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYRSE 480
K ++ +G+LDI+GFE FE+NSFEQ IN+ NE LQQ F++ EQEEY E
Sbjct: 373 --KAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIRE 430
Query: 481 NISWDYIHYTDNRPTLDLLALKPMSIISLLDEESRFP-QGTDLTMLQKLNSVHANNK--- 536
+I W +I Y +N DL+ I+++LDEE P TD T L+KLN V A ++
Sbjct: 431 DIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHFE 490
Query: 537 -------AFLQPKNIHDARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFL 589
FL ++ + F I H+AG+V YQ EGF++KN D+L D+ ++ + + +
Sbjct: 491 SRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKASHALI 550
Query: 590 REIFNLELAETKLGHGTIRQAKAGNHLFKSADSNKRPSTLGSQFKQSLDQLMKILTNCQP 649
+ +F GN + + KRP T GSQFK S+ LMK L P
Sbjct: 551 KSLF-----------------PEGN---PAKINLKRPPTAGSQFKASVATLMKNLQTKNP 590
Query: 650 YFIRCIKPNEYKKPLLFDRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLP 709
+IRCIKPN+ K +F+ L Q+RY G++E V +R++G+ R +E +R+ +L
Sbjct: 591 NYIRCIKPNDKKAAHIFNEALVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCK 650
Query: 710 NAMRMQLQGKLRQMTLGITDVWLRTDKDWKAGKTKIFLRDHQDTL-LEVQRSQVLDRAAL 768
+G R + + +++ G++KIF+R+ + LE R Q L+ A
Sbjct: 651 QTW-PHWKGPARSGVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLAT 709
Query: 769 SIQKVLRGYRYRKEFLRQRRAAVTLQAWWRGYCNRRNFKLILVGFERLQAIARSQPLARQ 828
IQK+ RG++ R FL +++ + + AW+R Y + ++
Sbjct: 710 LIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQ-----------------------KR 746
Query: 829 YQAMRQRTVQLQALCRGY----LVRQQVQAKR--RAVVVIQAHARGMAARRNFQQRKANA 882
YQ + + +Q+ RG+ ++R+ KR AV I A+ G ARR ++ K A
Sbjct: 747 YQQTKSSALVIQSYIRGWKARKILRELKHQKRCKEAVTTIAAYWHGTQARRELRRLKEEA 806
>gi|134288915 myosin IIIB isoform 1 [Homo sapiens]
Length = 1314
Score = 503 bits (1294), Expect = e-141
Identities = 298/770 (38%), Positives = 448/770 (58%), Gaps = 61/770 (7%)
Query: 68 DDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQVQLYYSRHM 127
DD++ L L+E ++H L RY IYTY G IL+A+NPFQ L +Y+ + +LY+
Sbjct: 346 DDLVNLEVLDEDTIIHQLQKRYADLLIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKR 405
Query: 128 GELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATIS-GQHSWIE 186
PPH+FA A+ Y M +DQC +ISGESG+GKTE+ LI+Q L + + +
Sbjct: 406 ASNPPHIFASADAAYQCMVTLSKDQCIVISGESGSGKTESAHLIVQHLTFLGKANNQTLR 465
Query: 187 QQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKSRVCRQA 246
+++L+ N ++EAFGN+ T NDNSSRFGKY+++ F P+GV+ GARI ++LLEKSRV +QA
Sbjct: 466 EKILQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTPTGVVMGARISEYLLEKSRVIKQA 525
Query: 247 PEERNYHIFYCMLMGVSAEDKQLLSLGTPSEY--HYLT------MGNCTSCEGLNDAKDY 298
E+N+HIFY + G+ + K+L P E Y+ M + TS E + +
Sbjct: 526 AREKNFHIFYYIYAGLHHQ-KKLSDFRLPEEKPPRYIADETGRVMHDITSKESYR--RQF 582
Query: 299 AHIRSAMKILQFSDSESWDVIKLLAAILHLGNVGFMA-SVFENLDASDVMETPAFPTVMK 357
I+ +I+ F+D E V ++LA IL++GN+ F A S D S+V A
Sbjct: 583 EAIQHCFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQHQTDKSEVPNAEALQNAAS 642
Query: 358 LLEVQHQELRDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAA 417
+L + +EL++ L H ++ RGE + R+ + +AAD RDA K +YG LF WIV +IN
Sbjct: 643 VLCISPEELQEALTSHCVVTRGETIIRANTVDRAADVRDAMSKALYGRLFSWIVNRINTL 702
Query: 418 IFTPPAQDPKNVRRA-----IGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTM 472
+ Q +N+ A +G+LDIFGFENF+ NSFEQLCIN ANE +Q +F QHVF +
Sbjct: 703 L-----QPDENICSAGGGMNVGILDIFGFENFQRNSFEQLCINIANEQIQYYFNQHVFAL 757
Query: 473 EQEEYRSENISWDYIHYTDNRPTLDLLALKPMSIISLLDEESRFPQGTDLTMLQKLNSVH 532
EQ EY++E I + Y DNRP LD+ KP+ +++LLDEESRFPQ TD T++ K +
Sbjct: 758 EQMEYQNEGIDAVPVEYEDNRPLLDMFLQKPLGLLALLDEESRFPQATDQTLVDKFED-N 816
Query: 533 ANNKAFLQPKNIHDARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLREI 592
K F +PK + + FGI H+AG+V Y A G LEKNRD L D++ ++ +S+N L+++
Sbjct: 817 LRCKYFWRPKGV-ELCFGIQHYAGKVLYDASGVLEKNRDTLPADVVVVLRTSENMLLQQL 875
Query: 593 FNLELAETKLGHGTIRQAKAGNHLFKSA-----------------------DSNKRPSTL 629
F++ L +T G + Q +A + S+ +N + T+
Sbjct: 876 FSIPLTKT----GNLAQTRARITVASSSLPPHFSAGKAKVDTLEVIRHPEETTNMKRQTV 931
Query: 630 GSQFKQSLDQLMKILTNCQPYFIRCIKPNEYKKPLLFDRELCLRQLRYSGMMETVHIRKS 689
S F+ SL L+ + QP+F+RCIKPN+ ++ L F RE L QLR +G++ETV IR+
Sbjct: 932 ASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREALQFSRERVLAQLRSTGILETVSIRRQ 991
Query: 690 GFPIRYTFEEFSQRFGVLLPNAMRMQLQGKLRQMTLGITDVWLRTDKDWKAGKTKIFLRD 749
G+ R FEEF +R+ L A + L K + + I + R D W GKTK+FL+
Sbjct: 992 GYSHRILFEEFVKRYYYLAFTAHQTPLASK--ESCVAILEK-SRLD-HWVLGKTKVFLKY 1047
Query: 750 HQDTLLEVQRSQVLDRAALSIQKVLRGY----RYRKEFLRQRRAAVTLQA 795
+ L + +V+ R + +Q +G+ RY+K ++ + A+ +Q+
Sbjct: 1048 YHVEQLNLLLREVIGRVVV-LQAYTKGWLGARRYKKVREKREKGAIAIQS 1096
>gi|44889481 myosin IB isoform 2 [Homo sapiens]
Length = 1078
Score = 500 bits (1288), Expect = e-141
Identities = 303/841 (36%), Positives = 472/841 (56%), Gaps = 73/841 (8%)
Query: 66 GVDDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQVQLYYSR 125
GV DM+ L LNE ++NL R+ +IYTY GS++++VNP++ LP+Y+ E+V+ Y +R
Sbjct: 16 GVGDMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYRNR 75
Query: 126 HMGELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATISGQHSWI 185
+ EL PH+FA+++ Y S++ +DQC +I+GESGAGKTE +KL++ ++A + G+ + +
Sbjct: 76 NFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEV 135
Query: 186 EQ---QVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKSRV 242
Q Q+L++NP+LEAFGNAKT+RNDNSSRFGKY+DI F+ G G I +LLEKSRV
Sbjct: 136 NQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRV 195
Query: 243 CRQAPEERNYHIFYCMLMGVSAEDKQLLSLGTP-SEYHYLTMGNCTSCEGLNDAKDYAHI 301
+Q ERN+H+FY +L G S E L L S Y+YL++ + G++DA ++ +
Sbjct: 196 VKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSL-DSAKVNGVDDAANFRTV 254
Query: 302 RSAMKILQFSDSESWDVIKLLAAILHLGNVGFM-ASVFENLDASDVMETPAFPTVMKLLE 360
R+AM+I+ F D E+ V+ ++AA+L LGN+ F S LD S + + + +L
Sbjct: 255 RNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELTG 314
Query: 361 VQHQELRDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIFT 420
+ L T+ + E V+ +LN+AQA RDA K +Y LF W+V +IN +I
Sbjct: 315 IDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESI-- 372
Query: 421 PPAQDPKNVRRAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYRSE 480
K ++ +G+LDI+GFE FE+NSFEQ IN+ NE LQQ F++ EQEEY E
Sbjct: 373 --KAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIRE 430
Query: 481 NISWDYIHYTDNRPTLDLLALKPMSIISLLDEESRFP-QGTDLTMLQKLNSVHANNK--- 536
+I W +I Y +N DL+ I+++LDEE P TD T L+KLN V A ++
Sbjct: 431 DIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHFE 490
Query: 537 -------AFLQPKNIHDARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFL 589
FL ++ + F I H+AG+V YQ EGF++KN D+L D+ ++ + + +
Sbjct: 491 SRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKASHALI 550
Query: 590 REIFNLELAETKLGHGTIRQAKAGNHLFKSADSNKRPSTLGSQFKQSLDQLMKILTNCQP 649
+ +F GN + + KRP T GSQFK S+ LMK L P
Sbjct: 551 KSLF-----------------PEGN---PAKINLKRPPTAGSQFKASVATLMKNLQTKNP 590
Query: 650 YFIRCIKPNEYKKPLLFDRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLP 709
+IRCIKPN+ K +F+ L Q+RY G++E V +R++G+ R +E +R+ +L
Sbjct: 591 NYIRCIKPNDKKAAHIFNEALVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCK 650
Query: 710 NAMRMQLQGKLRQMTLGITDVWLRTDKDWKAGKTKIFLRDHQDTL-LEVQRSQVLDRAAL 768
+G R + + +++ G++KIF+R+ + LE R Q L+ A
Sbjct: 651 QTW-PHWKGPARSGVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLAT 709
Query: 769 SIQKVLRGYRYRKEFLRQRRAAVTLQAWWRGYCNRRNFKLILVGFERLQAIARSQPLARQ 828
IQK+ RG++ R FL +++ + + AW+R Y + ++
Sbjct: 710 LIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQ-----------------------KR 746
Query: 829 YQAMRQRTVQLQALCRGY----LVRQQVQAKR--RAVVVIQAHARGMAARRNFQQ-RKAN 881
YQ + + +Q+ RG+ ++R+ KR AV I A+ G RR +++ +AN
Sbjct: 747 YQQTKSSALVIQSYIRGWKARKILRELKHQKRCKEAVTTIAAYWHGTQVRREYRKFFRAN 806
Query: 882 A 882
A
Sbjct: 807 A 807
>gi|145275208 myosin IIIA [Homo sapiens]
Length = 1616
Score = 491 bits (1263), Expect = e-138
Identities = 294/780 (37%), Positives = 443/780 (56%), Gaps = 39/780 (5%)
Query: 62 NSVQGVDDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQVQL 121
++++ VDD+ L L+E + L Y + +IY Y G IL+A+NPFQ L LY+ + +L
Sbjct: 335 SNLKDVDDLATLEILDENTVSEQLEKCYSRDQIYVYVGDILIALNPFQSLGLYSTKHSKL 394
Query: 122 YYSRHMGELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATIS-G 180
Y PPH+FA+A+ Y SM DQC +ISGESGAGKTE L++Q L +
Sbjct: 395 YIGSKRTASPPHIFAMADLGYQSMITYNSDQCIVISGESGAGKTENAHLLVQQLTVLGKA 454
Query: 181 QHSWIEQQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKS 240
+ +++++L+ N ++EAFGNA TI NDNSSRFGKY+++ F SG + GA+I ++LLEKS
Sbjct: 455 NNRTLQEKILQVNNLVEAFGNACTIINDNSSRFGKYLEMKFTSSGAVVGAQISEYLLEKS 514
Query: 241 RVCRQAPEERNYHIFYCMLMGVSAEDKQLLSLGTPSEY--HYLTMGNCTSCEGLND---- 294
RV QA E+N+HIFY + G+ AE K+L P YL + + + + +
Sbjct: 515 RVIHQAIGEKNFHIFYYIYAGL-AEKKKLAHYKLPENKPPRYLQNDHLRTVQDIMNNSFY 573
Query: 295 AKDYAHIRSAMKILQFSDSESWDVIKLLAAILHLGNVGFMASVFEN-LDASDVMETPAFP 353
Y I K++ F+ + + +LAAIL++GN+ F + E+ +D S + A
Sbjct: 574 KSQYELIEQCFKVIGFTMEQLGSIYSILAAILNVGNIEFSSVATEHQIDKSHISNHTALE 633
Query: 354 TVMKLLEVQHQELRDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKK 413
LL ++ EL++ L H ++ RGE + R + +A D RDA K +YG LF WIV
Sbjct: 634 NCASLLCIRADELQEALTSHCVVTRGETIIRPNTVEKATDVRDAMAKTLYGRLFSWIVNC 693
Query: 414 INAAIFTPPAQDPKNVRRAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTME 473
IN+ + + +IG+LDIFGFENF+ NSFEQLCIN ANE +Q ++ QHVF E
Sbjct: 694 INSLLKHDSSPSGNGDELSIGILDIFGFENFKKNSFEQLCINIANEQIQYYYNQHVFAWE 753
Query: 474 QEEYRSENISWDYIHYTDNRPTLDLLALKPMSIISLLDEESRFPQGTDLTMLQKLNSVHA 533
Q EY +E++ I Y DN P LD+ KPM ++SLLDEESRFP+ TD T+++K +
Sbjct: 754 QNEYLNEDVDARVIEYEDNWPLLDMFLQKPMGLLSLLDEESRFPKATDQTLVEKFEG-NL 812
Query: 534 NNKAFLQPKNIHDARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLREIF 593
++ F +PK + + FGI H+AG+V Y A GFL KNRD L TDI+ L+ SS N +R++
Sbjct: 813 KSQYFWRPKRM-ELSFGIHHYAGKVLYNASGFLAKNRDTLPTDIVLLLRSSDNSVIRQLV 871
Query: 594 NLELAET-KLGHGTIR-----QAKAGNHLFKSA-------------DSNKRPSTLGSQFK 634
N L +T L H + Q + L A +N + T+ S F+
Sbjct: 872 NHPLTKTGNLPHSKTKNVINYQMRTSEKLINLAKGDTGEATRHARETTNMKTQTVASYFR 931
Query: 635 QSLDQLMKILTNCQPYFIRCIKPNEYKKPLLFDRELCLRQLRYSGMMETVHIRKSGFPIR 694
SL L+ + QP+F+RCIKPN ++ +D+E L QLRY+G++ET IR+ GF R
Sbjct: 932 YSLMDLLSKMVVGQPHFVRCIKPNSERQARKYDKEKVLLQLRYTGILETARIRRLGFSHR 991
Query: 695 YTFEEFSQRFGVLLPNAMRMQLQGKLRQMTLGITDVWLRTDKDWKAGKTKIFLRDHQDTL 754
F F +R+ +L + + ++ T D +W GKTK+FL+ +
Sbjct: 992 ILFANFIKRYYLL---CYKSSEEPRMSPDTCATILEKAGLD-NWALGKTKVFLKYYHVEQ 1047
Query: 755 LEVQRSQVLDRAALSIQKVLRGY----RYRKEFLRQRRAAVTLQAWWRGYCNRRNFKLIL 810
L + R + +D+ L IQ +R + RY+K +++ +A+ +Q+ RG+ R+ K I+
Sbjct: 1048 LNLMRKEAIDKLIL-IQACVRAFLCSRRYQKIQEKRKESAIIIQSAARGHLVRKQRKEIV 1106
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 485 bits (1248), Expect = e-136
Identities = 318/954 (33%), Positives = 514/954 (53%), Gaps = 59/954 (6%)
Query: 28 IKEAKPGKVLVE-DDEGKEHWIRAEDFGVLSPMHPNSVQGVDDMIRLGDLNEAGMVHNLL 86
IKE K +V+VE + GK+ + +D + M+P V+DM L LNEA ++HNL
Sbjct: 50 IKEEKGDEVVVELVENGKKVTVGKDD---IQKMNPPKFSKVEDMAELTCLNEASVLHNLR 106
Query: 87 IRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQVQLYYSRHMGELPPHVFAIANNCYFSMK 146
RY IYTY+G V VNP++ LP+Y+ + V +Y + E+PPH++AIA+ Y SM
Sbjct: 107 ERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSML 166
Query: 147 RNKRDQCCIISGESGAGKTETTKLILQFLATISGQHSW---------IEQQVLEANPILE 197
+++ DQ + +GESGAGKTE TK ++Q+LA ++ H +E+Q+L+ANPILE
Sbjct: 167 QDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSITGELEKQLLQANPILE 226
Query: 198 AFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKSRVCRQAPEERNYHIFYC 257
AFGNAKT++NDNSSRFGK+I I F+ +G I GA IE +LLEKSR RQA +ER +HIFY
Sbjct: 227 AFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYY 286
Query: 258 MLMGVSAEDKQLLSLGTPSEYHYLTMGNCTSCEGLNDAKDYAHIRSAMKILQFSDSESWD 317
M+ G + + L L + Y +L+ G D + + AM I+ FS+ E
Sbjct: 287 MIAGAKEKMRSDLLLEGFNNYTFLSNG-FVPIPAAQDDEMFQETVEAMAIMGFSEEEQLS 345
Query: 318 VIKLLAAILHLGNVGFMASVFENLDASDVMETPAFPTVMKLLEVQHQELRDCLIKHTILI 377
++K+++++L LGN+ F N D + + + A V L+ + + ++ I +
Sbjct: 346 ILKVVSSVLQLGNIVFKKE--RNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKV 403
Query: 378 RGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIFTPPAQDPKNVRRAIGLLD 437
+ V ++ QA +A K Y LF WI+ ++N A+ Q +G+LD
Sbjct: 404 GRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGAS----FLGILD 459
Query: 438 IFGFENFENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYRSENISWDYIHY-TDNRPTL 496
I GFE FE NSFEQLCIN+ NE LQQ F +F +EQEEY+ E I W++I + D +P +
Sbjct: 460 IAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCI 519
Query: 497 DLLAL--KPMSIISLLDEESRFPQGTDLTMLQKLNSVHANNKAFLQPKNIHD-ARFGIAH 553
+L+ P +++LLDEE FP+ TD + ++KL + ++ F +PK + D F I H
Sbjct: 520 ELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIH 579
Query: 554 FAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLREIFNLELAETKLGHGTIRQAKAG 613
+AG+V Y A +L KN D L+ ++ +L+ +S +KF+ +++ + G + AK
Sbjct: 580 YAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWK----DVDRIVGLDQMAKMT 635
Query: 614 NHLFKSADSNKRP--STLGSQFKQSLDQLMKILTNCQPYFIRCIKPNEYKKPLLFDRELC 671
SA K+ T+G +K+ L +LM L N P F+RCI PN K+ D L
Sbjct: 636 ESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLV 695
Query: 672 LRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPNAMRMQLQGKLRQMTLGITDVW 731
L QLR +G++E + I + GFP R F+EF QR+ +L NA+ + L I +
Sbjct: 696 LEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALE 755
Query: 732 LRTDKDWKAGKTKIFLRDHQDTLLEVQRSQVLDRAALSIQKVLRGYRYRKEFLRQRRAAV 791
L + ++ G++KIF R LE +R + ++ Q + RGY RK F ++++
Sbjct: 756 LDPNL-YRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLT 814
Query: 792 TLQAWWR---GYCNRRNFKLILVGFERLQAIARSQPLARQYQAMRQRTVQLQALCRGYLV 848
++ R Y RN++ + F +++ + + + RQ + M+ + +LQ
Sbjct: 815 AMKVIQRNCAAYLKLRNWQWWRL-FTKVKPLLQ---VTRQEEEMQAKEDELQK-----TK 865
Query: 849 RQQVQAKRRAVVVIQAHARGMAARRNFQQRKANAPLVIPAEGQKSQGALPAKKRRSIYDT 908
+Q +A+ + Q H++ + +N Q + A + AE ++ + L AKK+
Sbjct: 866 ERQQKAENELKELEQKHSQ-LTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQE----- 919
Query: 909 VTDTEMVEKVFGFLPAMIGGQEGQASPHFEDLESKTQKLLEVDLDTVPMAEEPE 962
+E++ + A + +E + + L+++ +K+ + LD EE E
Sbjct: 920 ------LEEILHEMEARLEEEEDRG----QQLQAERKKMAQQMLDLEEQLEEEE 963
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 485 bits (1248), Expect = e-136
Identities = 318/954 (33%), Positives = 514/954 (53%), Gaps = 59/954 (6%)
Query: 28 IKEAKPGKVLVE-DDEGKEHWIRAEDFGVLSPMHPNSVQGVDDMIRLGDLNEAGMVHNLL 86
IKE K +V+VE + GK+ + +D + M+P V+DM L LNEA ++HNL
Sbjct: 50 IKEEKGDEVVVELVENGKKVTVGKDD---IQKMNPPKFSKVEDMAELTCLNEASVLHNLR 106
Query: 87 IRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQVQLYYSRHMGELPPHVFAIANNCYFSMK 146
RY IYTY+G V VNP++ LP+Y+ + V +Y + E+PPH++AIA+ Y SM
Sbjct: 107 ERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSML 166
Query: 147 RNKRDQCCIISGESGAGKTETTKLILQFLATISGQHSW---------IEQQVLEANPILE 197
+++ DQ + +GESGAGKTE TK ++Q+LA ++ H +E+Q+L+ANPILE
Sbjct: 167 QDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSITGELEKQLLQANPILE 226
Query: 198 AFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKSRVCRQAPEERNYHIFYC 257
AFGNAKT++NDNSSRFGK+I I F+ +G I GA IE +LLEKSR RQA +ER +HIFY
Sbjct: 227 AFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYY 286
Query: 258 MLMGVSAEDKQLLSLGTPSEYHYLTMGNCTSCEGLNDAKDYAHIRSAMKILQFSDSESWD 317
M+ G + + L L + Y +L+ G D + + AM I+ FS+ E
Sbjct: 287 MIAGAKEKMRSDLLLEGFNNYTFLSNG-FVPIPAAQDDEMFQETVEAMAIMGFSEEEQLS 345
Query: 318 VIKLLAAILHLGNVGFMASVFENLDASDVMETPAFPTVMKLLEVQHQELRDCLIKHTILI 377
++K+++++L LGN+ F N D + + + A V L+ + + ++ I +
Sbjct: 346 ILKVVSSVLQLGNIVFKKE--RNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKV 403
Query: 378 RGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIFTPPAQDPKNVRRAIGLLD 437
+ V ++ QA +A K Y LF WI+ ++N A+ Q +G+LD
Sbjct: 404 GRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGAS----FLGILD 459
Query: 438 IFGFENFENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYRSENISWDYIHY-TDNRPTL 496
I GFE FE NSFEQLCIN+ NE LQQ F +F +EQEEY+ E I W++I + D +P +
Sbjct: 460 IAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCI 519
Query: 497 DLLAL--KPMSIISLLDEESRFPQGTDLTMLQKLNSVHANNKAFLQPKNIHD-ARFGIAH 553
+L+ P +++LLDEE FP+ TD + ++KL + ++ F +PK + D F I H
Sbjct: 520 ELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIH 579
Query: 554 FAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLREIFNLELAETKLGHGTIRQAKAG 613
+AG+V Y A +L KN D L+ ++ +L+ +S +KF+ +++ + G + AK
Sbjct: 580 YAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWK----DVDRIVGLDQMAKMT 635
Query: 614 NHLFKSADSNKRP--STLGSQFKQSLDQLMKILTNCQPYFIRCIKPNEYKKPLLFDRELC 671
SA K+ T+G +K+ L +LM L N P F+RCI PN K+ D L
Sbjct: 636 ESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLV 695
Query: 672 LRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPNAMRMQLQGKLRQMTLGITDVW 731
L QLR +G++E + I + GFP R F+EF QR+ +L NA+ + L I +
Sbjct: 696 LEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALE 755
Query: 732 LRTDKDWKAGKTKIFLRDHQDTLLEVQRSQVLDRAALSIQKVLRGYRYRKEFLRQRRAAV 791
L + ++ G++KIF R LE +R + ++ Q + RGY RK F ++++
Sbjct: 756 LDPNL-YRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLT 814
Query: 792 TLQAWWR---GYCNRRNFKLILVGFERLQAIARSQPLARQYQAMRQRTVQLQALCRGYLV 848
++ R Y RN++ + F +++ + + + RQ + M+ + +LQ
Sbjct: 815 AMKVIQRNCAAYLKLRNWQWWRL-FTKVKPLLQ---VTRQEEEMQAKEDELQK-----TK 865
Query: 849 RQQVQAKRRAVVVIQAHARGMAARRNFQQRKANAPLVIPAEGQKSQGALPAKKRRSIYDT 908
+Q +A+ + Q H++ + +N Q + A + AE ++ + L AKK+
Sbjct: 866 ERQQKAENELKELEQKHSQ-LTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQE----- 919
Query: 909 VTDTEMVEKVFGFLPAMIGGQEGQASPHFEDLESKTQKLLEVDLDTVPMAEEPE 962
+E++ + A + +E + + L+++ +K+ + LD EE E
Sbjct: 920 ------LEEILHEMEARLEEEEDRG----QQLQAERKKMAQQMLDLEEQLEEEE 963
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 482 bits (1241), Expect = e-135
Identities = 318/961 (33%), Positives = 514/961 (53%), Gaps = 66/961 (6%)
Query: 28 IKEAKPGKVLVE-DDEGKEHWIRAEDFGVLSPMHPNSVQGVDDMIRLGDLNEAGMVHNLL 86
IKE K +V+VE + GK+ + +D + M+P V+DM L LNEA ++HNL
Sbjct: 50 IKEEKGDEVVVELVENGKKVTVGKDD---IQKMNPPKFSKVEDMAELTCLNEASVLHNLR 106
Query: 87 IRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQVQLYYSRHMGELPPHVFAIANNCYFSMK 146
RY IYTY+G V VNP++ LP+Y+ + V +Y + E+PPH++AIA+ Y SM
Sbjct: 107 ERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSML 166
Query: 147 RNKRDQCCIISGESGAGKTETTKLILQFLATISGQHSW----------------IEQQVL 190
+++ DQ + +GESGAGKTE TK ++Q+LA ++ H +E+Q+L
Sbjct: 167 QDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSITQGPSFAYGELEKQLL 226
Query: 191 EANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKSRVCRQAPEER 250
+ANPILEAFGNAKT++NDNSSRFGK+I I F+ +G I GA IE +LLEKSR RQA +ER
Sbjct: 227 QANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDER 286
Query: 251 NYHIFYCMLMGVSAEDKQLLSLGTPSEYHYLTMGNCTSCEGLNDAKDYAHIRSAMKILQF 310
+HIFY M+ G + + L L + Y +L+ G D + + AM I+ F
Sbjct: 287 TFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNG-FVPIPAAQDDEMFQETVEAMAIMGF 345
Query: 311 SDSESWDVIKLLAAILHLGNVGFMASVFENLDASDVMETPAFPTVMKLLEVQHQELRDCL 370
S+ E ++K+++++L LGN+ F N D + + + A V L+ + + +
Sbjct: 346 SEEEQLSILKVVSSVLQLGNIVFKKE--RNTDQASMPDNTAAQKVCHLMGINVTDFTRSI 403
Query: 371 IKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIFTPPAQDPKNVR 430
+ I + + V ++ QA +A K Y LF WI+ ++N A+ Q
Sbjct: 404 LTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGAS--- 460
Query: 431 RAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYRSENISWDYIHY- 489
+G+LDI GFE FE NSFEQLCIN+ NE LQQ F +F +EQEEY+ E I W++I +
Sbjct: 461 -FLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFG 519
Query: 490 TDNRPTLDLLAL--KPMSIISLLDEESRFPQGTDLTMLQKLNSVHANNKAFLQPKNIHD- 546
D +P ++L+ P +++LLDEE FP+ TD + ++KL + ++ F +PK + D
Sbjct: 520 LDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDK 579
Query: 547 ARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLREIFNLELAETKLGHGT 606
F I H+AG+V Y A +L KN D L+ ++ +L+ +S +KF+ +++ + G
Sbjct: 580 TEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWK----DVDRIVGL 635
Query: 607 IRQAKAGNHLFKSADSNKRP--STLGSQFKQSLDQLMKILTNCQPYFIRCIKPNEYKKPL 664
+ AK SA K+ T+G +K+ L +LM L N P F+RCI PN K+
Sbjct: 636 DQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSG 695
Query: 665 LFDRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPNAMRMQLQGKLRQMT 724
D L L QLR +G++E + I + GFP R F+EF QR+ +L NA+ +
Sbjct: 696 KLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACI 755
Query: 725 LGITDVWLRTDKDWKAGKTKIFLRDHQDTLLEVQRSQVLDRAALSIQKVLRGYRYRKEFL 784
L I + L + ++ G++KIF R LE +R + ++ Q + RGY RK F
Sbjct: 756 LMIKALELDPNL-YRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFA 814
Query: 785 RQRRAAVTLQAWWR---GYCNRRNFKLILVGFERLQAIARSQPLARQYQAMRQRTVQLQA 841
++++ ++ R Y RN++ + F +++ + + + RQ + M+ + +LQ
Sbjct: 815 KRQQQLTAMKVIQRNCAAYLKLRNWQWWRL-FTKVKPLLQ---VTRQEEEMQAKEDELQK 870
Query: 842 LCRGYLVRQQVQAKRRAVVVIQAHARGMAARRNFQQRKANAPLVIPAEGQKSQGALPAKK 901
+Q +A+ + Q H++ + +N Q + A + AE ++ + L AKK
Sbjct: 871 -----TKERQQKAENELKELEQKHSQ-LTEEKNLLQEQLQAETELYAEAEEMRVRLAAKK 924
Query: 902 RRSIYDTVTDTEMVEKVFGFLPAMIGGQEGQASPHFEDLESKTQKLLEVDLDTVPMAEEP 961
+ +E++ + A + +E + + L+++ +K+ + LD EE
Sbjct: 925 QE-----------LEEILHEMEARLEEEEDRG----QQLQAERKKMAQQMLDLEEQLEEE 969
Query: 962 E 962
E
Sbjct: 970 E 970
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 482 bits (1241), Expect = e-135
Identities = 318/961 (33%), Positives = 514/961 (53%), Gaps = 66/961 (6%)
Query: 28 IKEAKPGKVLVE-DDEGKEHWIRAEDFGVLSPMHPNSVQGVDDMIRLGDLNEAGMVHNLL 86
IKE K +V+VE + GK+ + +D + M+P V+DM L LNEA ++HNL
Sbjct: 50 IKEEKGDEVVVELVENGKKVTVGKDD---IQKMNPPKFSKVEDMAELTCLNEASVLHNLR 106
Query: 87 IRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQVQLYYSRHMGELPPHVFAIANNCYFSMK 146
RY IYTY+G V VNP++ LP+Y+ + V +Y + E+PPH++AIA+ Y SM
Sbjct: 107 ERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSML 166
Query: 147 RNKRDQCCIISGESGAGKTETTKLILQFLATISGQHSW----------------IEQQVL 190
+++ DQ + +GESGAGKTE TK ++Q+LA ++ H +E+Q+L
Sbjct: 167 QDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSITQGPSFAYGELEKQLL 226
Query: 191 EANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKSRVCRQAPEER 250
+ANPILEAFGNAKT++NDNSSRFGK+I I F+ +G I GA IE +LLEKSR RQA +ER
Sbjct: 227 QANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDER 286
Query: 251 NYHIFYCMLMGVSAEDKQLLSLGTPSEYHYLTMGNCTSCEGLNDAKDYAHIRSAMKILQF 310
+HIFY M+ G + + L L + Y +L+ G D + + AM I+ F
Sbjct: 287 TFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNG-FVPIPAAQDDEMFQETVEAMAIMGF 345
Query: 311 SDSESWDVIKLLAAILHLGNVGFMASVFENLDASDVMETPAFPTVMKLLEVQHQELRDCL 370
S+ E ++K+++++L LGN+ F N D + + + A V L+ + + +
Sbjct: 346 SEEEQLSILKVVSSVLQLGNIVFKKE--RNTDQASMPDNTAAQKVCHLMGINVTDFTRSI 403
Query: 371 IKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIFTPPAQDPKNVR 430
+ I + + V ++ QA +A K Y LF WI+ ++N A+ Q
Sbjct: 404 LTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGAS--- 460
Query: 431 RAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYRSENISWDYIHY- 489
+G+LDI GFE FE NSFEQLCIN+ NE LQQ F +F +EQEEY+ E I W++I +
Sbjct: 461 -FLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFG 519
Query: 490 TDNRPTLDLLAL--KPMSIISLLDEESRFPQGTDLTMLQKLNSVHANNKAFLQPKNIHD- 546
D +P ++L+ P +++LLDEE FP+ TD + ++KL + ++ F +PK + D
Sbjct: 520 LDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDK 579
Query: 547 ARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLREIFNLELAETKLGHGT 606
F I H+AG+V Y A +L KN D L+ ++ +L+ +S +KF+ +++ + G
Sbjct: 580 TEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWK----DVDRIVGL 635
Query: 607 IRQAKAGNHLFKSADSNKRP--STLGSQFKQSLDQLMKILTNCQPYFIRCIKPNEYKKPL 664
+ AK SA K+ T+G +K+ L +LM L N P F+RCI PN K+
Sbjct: 636 DQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSG 695
Query: 665 LFDRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPNAMRMQLQGKLRQMT 724
D L L QLR +G++E + I + GFP R F+EF QR+ +L NA+ +
Sbjct: 696 KLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACI 755
Query: 725 LGITDVWLRTDKDWKAGKTKIFLRDHQDTLLEVQRSQVLDRAALSIQKVLRGYRYRKEFL 784
L I + L + ++ G++KIF R LE +R + ++ Q + RGY RK F
Sbjct: 756 LMIKALELDPNL-YRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFA 814
Query: 785 RQRRAAVTLQAWWR---GYCNRRNFKLILVGFERLQAIARSQPLARQYQAMRQRTVQLQA 841
++++ ++ R Y RN++ + F +++ + + + RQ + M+ + +LQ
Sbjct: 815 KRQQQLTAMKVIQRNCAAYLKLRNWQWWRL-FTKVKPLLQ---VTRQEEEMQAKEDELQK 870
Query: 842 LCRGYLVRQQVQAKRRAVVVIQAHARGMAARRNFQQRKANAPLVIPAEGQKSQGALPAKK 901
+Q +A+ + Q H++ + +N Q + A + AE ++ + L AKK
Sbjct: 871 -----TKERQQKAENELKELEQKHSQ-LTEEKNLLQEQLQAETELYAEAEEMRVRLAAKK 924
Query: 902 RRSIYDTVTDTEMVEKVFGFLPAMIGGQEGQASPHFEDLESKTQKLLEVDLDTVPMAEEP 961
+ +E++ + A + +E + + L+++ +K+ + LD EE
Sbjct: 925 QE-----------LEEILHEMEARLEEEEDRG----QQLQAERKKMAQQMLDLEEQLEEE 969
Query: 962 E 962
E
Sbjct: 970 E 970
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 481 bits (1239), Expect = e-135
Identities = 310/906 (34%), Positives = 489/906 (53%), Gaps = 39/906 (4%)
Query: 10 VWLEPPSTHKTGVAIGGIIKEAKPGKVLVEDDEGKEHWIRAEDFGVLSPMHPNSVQGVDD 69
VW+ + K+G + +E ++ + GK+ + +D + M+P V+D
Sbjct: 32 VWVP---SDKSGFEPASLKEEVGEEAIVELVENGKKVKVNKDD---IQKMNPPKFSKVED 85
Query: 70 MIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQVQLYYSRHMGE 129
M L LNEA ++HNL RY IYTY+G V +NP++ LP+Y+ E V++Y + E
Sbjct: 86 MAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHE 145
Query: 130 LPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATISGQH------S 183
+PPH++AI + Y SM +++ DQ + +GESGAGKTE TK ++Q+LA ++ H
Sbjct: 146 MPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKKDQG 205
Query: 184 WIEQQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKSRVC 243
+E+Q+L+ANPILEAFGNAKT++NDNSSRFGK+I I F+ +G I GA IE +LLEKSR
Sbjct: 206 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAI 265
Query: 244 RQAPEERNYHIFYCMLMGVSAEDKQLLSLGTPSEYHYLTMGNCTSCEGLNDAKDYAHIRS 303
RQA EER +HIFY +L G K L L ++Y +L+ G+ T G D +
Sbjct: 266 RQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLSNGHVT-IPGQQDKDMFQETME 324
Query: 304 AMKILQFSDSESWDVIKLLAAILHLGNVGFMASVFENLDASDVMETPAFPTVMKLLEVQH 363
AM+I+ + E ++++++ +L LGN+ F N D + + + A V LL +
Sbjct: 325 AMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKE--RNTDQASMPDNTAAQKVSHLLGINV 382
Query: 364 QELRDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIFTPPA 423
+ ++ I + ++V ++ QA +A K Y +F W+V +IN A+
Sbjct: 383 TDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALDKTKR 442
Query: 424 QDPKNVRRAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYRSENIS 483
Q IG+LDI GFE F+ NSFEQLCIN+ NE LQQ F +F +EQEEY+ E I
Sbjct: 443 QGAS----FIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIE 498
Query: 484 WDYIHY-TDNRPTLDLL--ALKPMSIISLLDEESRFPQGTDLTMLQKLNSVHANNKAFLQ 540
W++I + D +P +DL+ P I++LLDEE FP+ TD + ++K+ + F +
Sbjct: 499 WNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQEQGTHPKFQK 558
Query: 541 PKNIHD-ARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLREIFNLELAE 599
PK + D A F I H+AG+V Y+A+ +L KN D L+ +I TL++ S +KF+ E++
Sbjct: 559 PKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDRI 618
Query: 600 TKLGHGTIRQAKAGNHLFKSADSNKRPSTLGSQFKQSLDQLMKILTNCQPYFIRCIKPNE 659
L A FK+ R T+G +K+ L +LM L N P F+RCI PN
Sbjct: 619 IGLDQVAGMSETALPGAFKTRKGMFR--TVGQLYKEQLAKLMATLRNTNPNFVRCIIPNH 676
Query: 660 YKKPLLFDRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPNAMRMQLQGK 719
KK D L L QLR +G++E + I + GFP R F+EF QR+ +L PN++
Sbjct: 677 EKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKGFMDG 736
Query: 720 LRQMTLGITDVWLRTDKDWKAGKTKIFLRDHQDTLLEVQRSQVLDRAALSIQKVLRGYRY 779
+ L I + L ++ ++ G++K+F R LE +R + + Q RGY
Sbjct: 737 KQACVLMIKALELDSNL-YRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLA 795
Query: 780 RKEFLRQRR---AAVTLQAWWRGYCNRRNFKLILVGFERLQAIARSQPLARQYQAMRQRT 836
RK F ++++ A LQ Y RN++ + F +++ + + + A +
Sbjct: 796 RKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRL-FTKVKPLLQVSRQEEEMMAKEEEL 854
Query: 837 VQLQALCRGYLVRQQVQAKRRAVVVIQAHARGMAARRNFQQRKANAPLVIPAEGQKSQGA 896
V+++ +Q+ A+ R + ++ MA + Q+ + A + AE ++ +
Sbjct: 855 VKVR--------EKQLAAENRLTEMETLQSQLMAEKLQLQE-QLQAETELCAEAEELRAR 905
Query: 897 LPAKKR 902
L AKK+
Sbjct: 906 LTAKKQ 911
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 481 bits (1237), Expect = e-135
Identities = 316/931 (33%), Positives = 496/931 (53%), Gaps = 37/931 (3%)
Query: 28 IKEAKPGKVLVE-DDEGKEHWIRAEDFGVLSPMHPNSVQGVDDMIRLGDLNEAGMVHNLL 86
IKE + +V+VE + GK+ + +D + M+P V+DM L LNEA ++HNL
Sbjct: 50 IKEERGDEVMVELAENGKKAMVNKDD---IQKMNPPKFSKVEDMAELTCLNEASVLHNLK 106
Query: 87 IRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQVQLYYSRHMGELPPHVFAIANNCYFSMK 146
RY IYTY+G V +NP++ LP+Y+ +++Y + E+PPH++AI+ + Y M
Sbjct: 107 DRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKKRHEMPPHIYAISESAYRCML 166
Query: 147 RNKRDQCCIISGESGAGKTETTKLILQFLATISGQHSW---------IEQQVLEANPILE 197
+++ DQ + +GESGAGKTE TK ++Q+LA ++ H +E+Q+L+ANPILE
Sbjct: 167 QDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKGRKDHNIPGELERQLLQANPILE 226
Query: 198 AFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKSRVCRQAPEERNYHIFYC 257
+FGNAKT++NDNSSRFGK+I I F+ +G I GA IE +LLEKSR RQA +ER +HIFY
Sbjct: 227 SFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQ 286
Query: 258 MLMGVSAEDKQLLSLGTPSEYHYLTMGNCTSCEGLNDAKDYAHIRSAMKILQFSDSESWD 317
+L G K L L + Y +L+ G G D ++ AM I+ FS E
Sbjct: 287 LLSGAGEHLKSDLLLEGFNNYRFLSNG-YIPIPGQQDKDNFQETMEAMHIMGFSHEEILS 345
Query: 318 VIKLLAAILHLGNVGFMASVFENLDASDVMETPAFPTVMKLLEVQHQELRDCLIKHTILI 377
++K+++++L GN+ F N D + + E + LL + E ++ I +
Sbjct: 346 MLKVVSSVLQFGNISFKKE--RNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKV 403
Query: 378 RGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIFTPPAQDPKNVRRAIGLLD 437
++V ++ QA +A K Y LF W+V +IN A+ Q IG+LD
Sbjct: 404 GRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRINKALDRTKRQGAS----FIGILD 459
Query: 438 IFGFENFENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYRSENISWDYIHY-TDNRPTL 496
I GFE FE NSFEQLCIN+ NE LQQ F +F +EQEEY+ E I W++I + D +P +
Sbjct: 460 IAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCI 519
Query: 497 DLL--ALKPMSIISLLDEESRFPQGTDLTMLQKLNSVHANNKAFLQPKNIHD-ARFGIAH 553
DL+ P +++LLDEE FP+ TD T ++KL ++ F +P+ + D A F I H
Sbjct: 520 DLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQEQGSHSKFQKPRQLKDKADFCIIH 579
Query: 554 FAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLREIFNLELAETKLGHGTIRQAKAG 613
+AG+V Y+A+ +L KN D L+ ++ TL++ S ++F+ E++ L T A
Sbjct: 580 YAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAELWKDVDRIVGLDQVTGMTETAF 639
Query: 614 NHLFKSADSNKRPSTLGSQFKQSLDQLMKILTNCQPYFIRCIKPNEYKKPLLFDRELCLR 673
+K+ R T+G +K+SL +LM L N P F+RCI PN K+ D L L
Sbjct: 640 GSAYKTKKGMFR--TVGQLYKESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLD 697
Query: 674 QLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPNAMRMQLQGKLRQMTLGITDVWLR 733
QLR +G++E + I + GFP R F+EF QR+ +L PNA+ + I + L
Sbjct: 698 QLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNAIPKGFMDGKQACERMIRALELD 757
Query: 734 TDKDWKAGKTKIFLRDHQDTLLEVQRSQVLDRAALSIQKVLRGYRYRKEFLRQRRAAVTL 793
+ ++ G++KIF R LE +R + + Q V RGY RK F ++++ L
Sbjct: 758 PNL-YRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSAL 816
Query: 794 QAWWRGYCNRRNFKLILVGFERLQAIARSQPLARQYQAMRQRTVQLQALCRGYLVRQQVQ 853
+ R L L ++ + + +PL Q RQ +LQA L ++ Q
Sbjct: 817 KVLQRNCA----AYLKLRHWQWWRVFTKVKPL---LQVTRQEE-ELQAKDEELLKVKEKQ 868
Query: 854 AK-RRAVVVIQAHARGMAARRNFQQRKANAPLVIPAEGQKSQGALPAKKRRSIYDTVTDT 912
K + ++ + + +N + A + AE ++ + L AKK + + + + D
Sbjct: 869 TKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKK-QELEEILHDL 927
Query: 913 EMVEKVFGFLPAMIGGQEGQASPHFEDLESK 943
E + ++ ++ + H +DLE +
Sbjct: 928 ESRVEEEEERNQILQNEKKKMQAHIQDLEEQ 958
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta
[Homo sapiens]
Length = 1983
Score = 478 bits (1231), Expect = e-134
Identities = 316/857 (36%), Positives = 464/857 (54%), Gaps = 60/857 (7%)
Query: 30 EAKPGKVLVEDDEGKEHWIRAEDFGVLSPMHPNSVQGVDDMIRLGDLNEAGMVHNLLIRY 89
EA G+V VE + K +R + L PM+P ++DM + LNEA ++HNL RY
Sbjct: 94 EATGGRVTVETKDQKVLMVREAE---LQPMNPPRFDLLEDMAMMTHLNEASVLHNLRQRY 150
Query: 90 QQHKIYTYTGSILVAVNPFQVLPLYTLEQVQLYYSRHMGELPPHVFAIANNCYFSMKRNK 149
+ IYTY+G V +NP++ LP+YT V Y + + PPH++A+A+N Y M RN+
Sbjct: 151 ARWMIYTYSGLFCVTINPYKWLPVYTASVVAAYKGKRRSDSPPHIYAVADNAYNDMLRNR 210
Query: 150 RDQCCIISGESGAGKTETTKLILQ-----------------FLATISGQHSWIEQQVLEA 192
+Q +I+GESGAGKT TK ++Q FLAT +G +E Q++EA
Sbjct: 211 DNQSMLITGESGAGKTVNTKRVIQYFAIVAALGDGPGKKAQFLATKTG--GTLEDQIIEA 268
Query: 193 NPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKSRVCRQAPEERNY 252
NP +EAFGNAKT+RNDNSSRFGK+I I+F PSG + A I+ +LLEKSRV Q P ER+Y
Sbjct: 269 NPAMEAFGNAKTLRNDNSSRFGKFIRIHFGPSGKLASADIDSYLLEKSRVIFQLPGERSY 328
Query: 253 HIFYCMLMGVSAEDKQLLSLG-TPSEYHYLTMGNCTSCEGLNDAKDYAHIRSAMKILQFS 311
H++Y +L G E + +L L P +YH+ + G T + +ND ++ AM IL FS
Sbjct: 329 HVYYQILSGRKPELQDMLLLSMNPYDYHFCSQGVIT-VDNMNDGEELIATDHAMDILGFS 387
Query: 312 DSESWDVIKLLAAILHLGNVGFMASVFENLDASDVMETPAFPTVMKLLEVQHQELRDCLI 371
E K++ A+LH GN+ F E +D T + L+ V +L L+
Sbjct: 388 VDEKCACYKIVGALLHFGNMKFKQKQREEQAEAD--GTESADKAAYLMGVSSGDLLKGLL 445
Query: 372 KHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIFTPPAQDPKNVRR 431
+ + E+VT+ ++ Q A K Y LF W+V +IN + D K R+
Sbjct: 446 HPRVRVGNEYVTKGQSVEQVVFAVGALAKATYDRLFRWLVSRINQTL------DTKLPRQ 499
Query: 432 -AIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYRSENISWDYIHY- 489
IG+LDI GFE FE NSFEQLCINF NE LQQFF QH+F +EQEEY+ E I W +I +
Sbjct: 500 FFIGVLDIAGFEIFEFNSFEQLCINFTNEKLQQFFNQHMFVLEQEEYKREGIDWVFIDFG 559
Query: 490 TDNRPTLDLLALKPMSIISLLDEESRFPQGTDLTMLQKLNSVHANNKA-FLQP----KNI 544
D +P +DL+ KP+ I+S+L+EE FP+ +D + KL HA F QP K
Sbjct: 560 LDLQPCIDLIE-KPLGILSILEEECMFPKASDASFRAKLYDNHAGKSPNFQQPRPDKKRK 618
Query: 545 HDARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLREIFNLELAETKLGH 604
+ A F + H+AG V Y G+LEKN+D L+ ++ + S+N+ L ++ E G
Sbjct: 619 YQAHFEVVHYAGVVPYSIVGWLEKNKDPLNETVVPIFQKSQNRLLATLY-----ENYAGS 673
Query: 605 GTIRQAKAG-NHLFKSADSNKRPSTLGSQFKQSLDQLMKILTNCQPYFIRCIKPNEYKKP 663
+ K+G K A S + T+ K++L++LM L QP+F+RCI PNE K P
Sbjct: 674 CSTEPPKSGVKEKRKKAASFQ---TVSQLHKENLNKLMTNLRATQPHFVRCIVPNENKTP 730
Query: 664 LLFDRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPNAM---RMQLQGKL 720
+ D L L QLR +G++E + I + GFP R + +F QR+ +L P+A+ K
Sbjct: 731 GVMDAFLVLHQLRCNGVLEGIRICRQGFPNRLLYTDFRQRYRILNPSAIPDDTFMDSRKA 790
Query: 721 RQMTLGITDVWLRTDKDWKAGKTKIFLRDHQDTLLEVQRSQVLDRAALSIQKVLRGYRYR 780
+ LG D+ ++ G TK+F + +LE R Q L + +Q RG R
Sbjct: 791 TEKLLGSLDL---DHTQYQFGHTKVFFKAGLLGVLEELRDQRLAKVLTLLQARSRGRLMR 847
Query: 781 KEFLR---QRRAAVTLQAWWRGYCNRRNFKLILVGFERLQAIARSQPLARQYQAMRQRTV 837
E+ R R A T+Q R + +N+ + + F +++ + RS + A+R
Sbjct: 848 LEYQRLLGGRDALFTIQWNIRAFNAVKNWSWMKL-FFKMKPLLRSAQAEEELAALRAELR 906
Query: 838 QLQ-ALCRGYLVRQQVQ 853
L+ AL RQ+++
Sbjct: 907 GLRGALAAAEAKRQELE 923
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 476 bits (1226), Expect = e-134
Identities = 304/846 (35%), Positives = 456/846 (53%), Gaps = 54/846 (6%)
Query: 34 GKVLVEDDEGKEHWIRAEDFGVLSPMHPNSVQGVDDMIRLGDLNEAGMVHNLLIRYQQHK 93
G V+VE +G+ I+ + + M+P + ++DM L LNEA ++H L RY Q
Sbjct: 75 GTVIVETADGESLSIKEDK---IQQMNPPEFEMIEDMAMLTHLNEASVLHTLKRRYGQWM 131
Query: 94 IYTYTGSILVAVNPFQVLPLYTLEQVQLYYSRHMGELPPHVFAIANNCYFSMKRNKRDQC 153
IYTY+G V +NP++ LP+Y E + Y + E PPH+FA+ANN + M N+ +Q
Sbjct: 132 IYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKRRSEAPPHIFAVANNAFQDMLHNRENQS 191
Query: 154 CIISGESGAGKTETTKLILQFLATISG------QHSWIEQQVLEANPILEAFGNAKTIRN 207
+ +GESGAGKT +K I+Q+ ATI+ + +E Q+++AN ILEAFGNAKT+RN
Sbjct: 192 ILFTGESGAGKTVNSKHIIQYFATIAAMIESRKKQGALEDQIMQANTILEAFGNAKTLRN 251
Query: 208 DNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKSRVCRQAPEERNYHIFYCMLMGVSAEDK 267
DNSSRFGK+I ++F G++ I+ +LLEKSRV Q ERNYHIFY +L G
Sbjct: 252 DNSSRFGKFIRMHFGARGMLSSVDIDIYLLEKSRVIFQQAGERNYHIFYQILSGQKELHD 311
Query: 268 QLLSLGTPSEYHYLTMGNCTSCEGLNDAKDYAHIRSAMKILQFSDSESWDVIKLLAAILH 327
LL PS++H+ + G T E L+DA++ AM IL F E + KL AI+H
Sbjct: 312 LLLVSANPSDFHFCSCGAVT-VESLDDAEELLATEQAMDILGFLPDEKYGCYKLTGAIMH 370
Query: 328 LGNVGFMASVFE---NLDASDVMETPAFPTVMKLLEVQHQELRDCLIKHTILIRGEFVTR 384
GN+ F E D ++ + AF L+ + EL CLI I + E+VTR
Sbjct: 371 FGNMKFKQKPREEQLEADGTENADKAAF-----LMGINSSELVKCLIHPRIKVGNEYVTR 425
Query: 385 SLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIFTPPAQDPKNVRR-AIGLLDIFGFEN 443
I Q A K +Y +F W+V +IN A+ D K R+ IG+LDI GFE
Sbjct: 426 GQTIEQVTCAVGALSKSMYERMFKWLVARINRAL------DAKLSRQFFIGILDITGFEI 479
Query: 444 FENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYRSENISWDYIHY-TDNRPTLDLLALK 502
E NS EQLCINF NE LQQFF H+F +EQEEY+ E+I W I + D + +DL+ K
Sbjct: 480 LEYNSLEQLCINFTNEKLQQFFNWHMFVLEQEEYKKESIEWVSIGFGLDLQACIDLIE-K 538
Query: 503 PMSIISLLDEESRFPQGTDLTMLQKLNSVHANNKAFLQ----PKNIHDARFGIAHFAGEV 558
PM I+S+L+EE FP+ TDLT KL H LQ K +A F + H+AG V
Sbjct: 539 PMGILSILEEECMFPKATDLTFKTKLFDNHFGKSVHLQKPKPDKKKFEAHFELVHYAGVV 598
Query: 559 YYQAEGFLEKNRDVLSTDILTLVYSSKNKFLREIF-NLELAETKLGHGTIRQAKAGNHLF 617
Y G+LEKN+D+L+ ++ + S N+ L +F N ++ + G ++ K +
Sbjct: 599 PYNISGWLEKNKDLLNETVVAVFQKSSNRLLASLFENYMSTDSAIPFGEKKRKKGASF-- 656
Query: 618 KSADSNKRPSTLGSQFKQSLDQLMKILTNCQPYFIRCIKPNEYKKPLLFDRELCLRQLRY 677
T+ S K++L++LM L + P+F+RCI PN K P + D L L+QLR
Sbjct: 657 ---------QTVASLHKENLNKLMTNLKSTAPHFVRCINPNVNKIPGILDPYLVLQQLRC 707
Query: 678 SGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPNAM---RMQLQGKLRQMTLGITDVWLRT 734
+G++E I + GFP R + +F QR+ +L P + K + LG ++
Sbjct: 708 NGVLEGTRICREGFPNRLQYADFKQRYCILNPRTFPKSKFVSSRKAAEELLGSLEI---D 764
Query: 735 DKDWKAGKTKIFLRDHQDTLLEVQRSQVLDRAALSIQKVLRGYRYRKEF---LRQRRAAV 791
++ G TK+F + LE R + L + Q +G R +F L +R A +
Sbjct: 765 HTQYRFGITKVFFKAGFLGQLEAIRDERLSKVFTLFQARAQGKLMRIKFQKILEERDALI 824
Query: 792 TLQAWWRGYCNRRNFKLILVGFERLQAIARSQPLARQYQAMRQRTVQLQ-ALCRGYLVRQ 850
+Q R + +N+ + + F +++ + +S + + +++ QLQ AL + R+
Sbjct: 825 LIQWNIRAFMAVKNWPWMRL-FFKIKPLVKSSEVGEEVAGLKEECAQLQKALEKSEFQRE 883
Query: 851 QVQAKR 856
+++AK+
Sbjct: 884 ELKAKQ 889
>gi|27544941 myosin IF [Homo sapiens]
Length = 1098
Score = 473 bits (1216), Expect = e-132
Identities = 291/796 (36%), Positives = 431/796 (54%), Gaps = 66/796 (8%)
Query: 60 HPNSVQGVDDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQV 119
H GVDDM+ L + E + NL R+ I+TY GS+L++VNPF+ +P +T ++
Sbjct: 12 HNVKQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREI 71
Query: 120 QLYYSRHMGELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATIS 179
LY E PPH++A+ +N Y +M + +QC IISGESGAGKT K I+ +++ +S
Sbjct: 72 DLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVS 131
Query: 180 G-----QHSWIEQQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQ 234
G QH ++ +L++NP+LEAFGNAKT+RN+NSSRFGKY +I F+ G +G +I
Sbjct: 132 GGGEKVQH--VKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISN 189
Query: 235 FLLEKSRVCRQAPEERNYHIFYCMLMGVSAEDKQLLSLGTPSEYHYLTMGNCTSCEGLND 294
FLLEKSRV Q ERN+HI+Y +L G S E +Q L L TP Y+YL + +G +D
Sbjct: 190 FLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSDTYQVDGTDD 249
Query: 295 AKDYAHIRSAMKILQFSDSESWDVIKLLAAILHLGNVGFMA-SVFENLDASDVMETPAFP 353
D+ SAM+++ S V++L+A ILHLGN+ F + +++ D++ PA+
Sbjct: 250 RSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESVDLLAFPAY- 308
Query: 354 TVMKLLEVQHQELRDCLIKHTILI----RGEFVTRSLNIAQAADRRDAFVKGIYGHLFLW 409
LL + L++ L + R E + +LN+ QAA RDA KG+Y LF +
Sbjct: 309 ----LLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDF 364
Query: 410 IVKKINAAIFTPPAQDPKNVRRAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHV 469
+V+ IN A+ P + +IG+LDI+GFE F+ N FEQ CINF NE LQQ F++
Sbjct: 365 LVEAINRAMQKPQEE------YSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELT 418
Query: 470 FTMEQEEYRSENISWDYIHYTDNRPTLDLL--ALKPMSIISLLDEESRFPQ----GTDLT 523
EQEEY E I W I Y +N+ DL+ L P I+S+LD+ G D T
Sbjct: 419 LKAEQEEYVQEGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQT 478
Query: 524 MLQKLNSVHANNKAFLQPKNIHDARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYS 583
+LQKL + ++ F N A F I H+AG+V Y GF E+NRDVL +D++ L+ +
Sbjct: 479 LLQKLQAAVGTHEHF----NSWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQT 534
Query: 584 SKNKFLREIFNLELAETKLGHGTIRQAKAGNHLFKSADSNKRPSTLGSQFKQSLDQLMKI 643
S+ FLR +F +L D RPST GS+ K+ + L+
Sbjct: 535 SEQAFLRMLFPEKL---------------------DGDKKGRPSTAGSKIKKQANDLVAT 573
Query: 644 LTNCQPYFIRCIKPNEYKKPLLFDRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQR 703
L C P++IRCIKPNE K+P ++ Q+ Y G+ E + +R++GF R F +F QR
Sbjct: 574 LMRCTPHYIRCIKPNETKRPRDWEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQR 633
Query: 704 FGVLLPNAMRMQLQGKLRQMTLGITDVWLRTDKDWKAGKTKIFLRDHQDT-LLEVQRSQV 762
+ +L P + +G RQ + ++ G TK+F+++ + LLE R +
Sbjct: 634 YAILTPETW-PRWRGDERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERK 692
Query: 763 LDRAALSIQKVLRGYRYRKEFLRQRRAAVTL---QAWWRGYCNRRNFKLILVGFERLQAI 819
D A +IQK R + +++ R A + + R RNF +G E
Sbjct: 693 FDGFARTIQKAWRRHVAVRKYEEMREEASNILLNKKERRRNSINRNFVGDYLGLE----- 747
Query: 820 ARSQPLARQYQAMRQR 835
+P RQ+ R+R
Sbjct: 748 --ERPELRQFLGKRER 761
>gi|254028267 myosin 1H [Homo sapiens]
Length = 1022
Score = 467 bits (1202), Expect = e-131
Identities = 280/760 (36%), Positives = 422/760 (55%), Gaps = 57/760 (7%)
Query: 66 GVDDMIRLGDL-NEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQVQLYYS 124
GV D + L +E+ V NL R+ ++ IYTY G++LV+VNP+Q L +YT+ Q++LY
Sbjct: 12 GVQDFVLLDAYTSESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGIYTVSQMELYQG 71
Query: 125 RHMGELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATISGQHSW 184
+ ELPPHV+AIA+N Y M + +ISGESGAGKTE +K IL++ A
Sbjct: 72 VNFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEASKKILEYFAVTCPMTQS 131
Query: 185 IE---QQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKSR 241
++ ++L +NP+LEAFGNA+T+RNDNSSRFGKY+DI F+ G+ G I +L+EKSR
Sbjct: 132 LQIARDRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGGHIISYLIEKSR 191
Query: 242 VCRQAPEERNYHIFYCMLMGVSAEDKQLLSLG---TPSEYHYLTMGNCTSCEGLNDAKDY 298
V Q ERN+HIFY +L G E+++L LG P Y YL+ G+C ++D D+
Sbjct: 192 VVYQNEGERNFHIFYQLLAG--GEEERLSYLGLERDPQLYKYLSQGHCAKESSISDKNDW 249
Query: 299 AHIRSAMKILQFSDSESWDVIKLLAAILHLGNVGFMASVFENLDASDVMETPAFPTVMKL 358
+ +A ++ F++++ ++ ++A++LHLGN+GF ++ + + +T + KL
Sbjct: 250 KTVSNAFSVIDFTEADLENLFGIIASVLHLGNIGFEE---DDQGCATIPDTHEIKWIAKL 306
Query: 359 LEVQHQELRDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAI 418
L V L + L I + E V L + + RDA K +YG F W+V KIN+++
Sbjct: 307 LGVHPSVLLEALTHRKIEAKTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVNKINSSL 366
Query: 419 FTPPAQDPKNVRRAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYR 478
+ IGLLDI+GFE F+ N FEQ CIN+ NE LQQ ++ EQ EY
Sbjct: 367 ----VNKDFTRKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAEYE 422
Query: 479 SENISWDYIHYTDNRPTLDLLALKPMSIISLLDEESRFP-QGTDLTMLQKLNS-----VH 532
E I W+ I Y +N+ DL+ + IIS+LDEE P TDL+ L+KL H
Sbjct: 423 MEGIEWEPIKYFNNKIICDLVEERHKGIISILDEECIRPGPATDLSFLEKLEEKVGKHAH 482
Query: 533 ANNKAFLQP---KNIHDARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFL 589
+ P K I F + H+AGEV Y +GFLEKN D+L + ++ SKN L
Sbjct: 483 FETRKLAGPKGRKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCKSKNIIL 542
Query: 590 REIFNLELAETKLGHGTIRQAKAGNHLFKSADSNKRPSTLGSQFKQSLDQLMKILTNCQP 649
RE F L ++ +RP T+G+QFK SL L++ L + +P
Sbjct: 543 RECF----------------------LLAELENRRRPPTVGTQFKNSLSSLLETLISKEP 580
Query: 650 YFIRCIKPNEYKKPLLFDRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLP 709
+IRCIKPN+ K+P FD L Q++Y G+ME + +R++GF R +E F QR+ L P
Sbjct: 581 SYIRCIKPNDRKEPSKFDDFLIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCP 640
Query: 710 NAMRMQLQGKLRQMTLGITDVWLRTDKDWKAGKTKIFLRDHQ-----DTLLEVQRSQVLD 764
+ G + + +++K GKTKIF+R + + E + Q++
Sbjct: 641 DTW-PHWHGPPAEGVERLIKYIGYKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVA 699
Query: 765 RAALSIQKVLRGYRYRKEFLRQRRAAVTLQAWWRGYCNRR 804
R + ++ L R+E++++R+AA+ L+A WRG R+
Sbjct: 700 RIQATYKRCLG----RREYVKKRQAAIKLEAHWRGALARK 735
Score = 34.7 bits (78), Expect = 1.0
Identities = 17/46 (36%), Positives = 28/46 (60%)
Query: 834 QRTVQLQALCRGYLVRQQVQAKRRAVVVIQAHARGMAARRNFQQRK 879
Q ++QA + L R++ KR+A + ++AH RG AR+ Q+RK
Sbjct: 696 QLVARIQATYKRCLGRREYVKKRQAAIKLEAHWRGALARKAIQRRK 741
>gi|4885503 myosin IA [Homo sapiens]
Length = 1043
Score = 464 bits (1194), Expect = e-130
Identities = 281/790 (35%), Positives = 438/790 (55%), Gaps = 44/790 (5%)
Query: 58 PMHPNSVQGVDDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLE 117
P+ SV GV+D++ L L E ++ NL +RY+ +IYTY G+++++VNP+Q LP+Y E
Sbjct: 2 PLLEGSV-GVEDLVLLEPLVEESLLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPE 60
Query: 118 QVQLYYSRHMGELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLAT 177
+ Y EL PH++A+AN Y S++ RDQC +I+GESG+GKTE +KL++ ++A
Sbjct: 61 FIAKYQDYTFYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAA 120
Query: 178 ISG---QHSWIEQQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQ 234
+ G Q + +++Q+L++NP+LEAFGNAKTIRN+NSSRFGKY+DI F+ G G I
Sbjct: 121 VCGKGEQVNSVKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITN 180
Query: 235 FLLEKSRVCRQAPEERNYHIFYCMLMGVSAEDKQLLSLGTPSEYHYLTMGNCTSCEGLND 294
+LLEKSR+ +Q ERN+HIFY +L G + + L L + + + +G++D
Sbjct: 181 YLLEKSRLVKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYLNHEVSRVDGMDD 240
Query: 295 AKDYAHIRSAMKILQFSDSESWDVIKLLAAILHLGNVGFMASVFE--NLDASDVMETPAF 352
A + ++SAM ++ FS+ E V+++ + +L LGNV +A F+ + AS + +
Sbjct: 241 ASSFRAVQSAMAVIGFSEEEIRQVLEVTSMVLKLGNV-LVADEFQASGIPASGIRDGRGV 299
Query: 353 PTVMKLLEVQHQELRDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVK 412
+ +++ + +E+ L T+ E V +LN+ QA RDA K IY LF WIV
Sbjct: 300 REIGEMVGLNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVN 359
Query: 413 KINAAIFTPPAQDPKNVRRAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTM 472
+IN +I + ++ +G+LDI+GFE E+NSFEQ IN+ NE LQQ F++
Sbjct: 360 RINESIKVGIGEK----KKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKE 415
Query: 473 EQEEYRSENISWDYIHYTDNRPTLDLLALKPMSIISLLDEESRFP-QGTDLTMLQKLNSV 531
EQEEY+ E I W + Y DN L+ I+++LDEE P +D T L KLN +
Sbjct: 416 EQEEYKREGIPWTKVDYFDNGIICKLIEHNQRGILAMLDEECLRPGVVSDSTFLAKLNQL 475
Query: 532 -----HANNKAFLQPKNIHDARFG-----IAHFAGEVYYQAEGFLEKNRDVLSTDILTLV 581
H +K + +D G I H+AG+V Y F++KN D+L D+L +
Sbjct: 476 FSKHGHYESKVTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLLQAM 535
Query: 582 YSSKNKFLREIFNLELAETKLGHGTIRQAKAGNHLFKSADSNKRPSTLGSQFKQSLDQLM 641
+ +++ LR +F G +QA S KRP T G+QFK S+ LM
Sbjct: 536 WKAQHPLLRSLF---------PEGNPKQA-----------SLKRPPTAGAQFKSSVAILM 575
Query: 642 KILTNCQPYFIRCIKPNEYKKPLLFDRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFS 701
K L + P +IRCIKPNE+++ F +L Q RY G++E V +R++G+ R + F
Sbjct: 576 KNLYSKSPNYIRCIKPNEHQQRGQFSSDLVATQARYLGLLENVRVRRAGYAHRQGYGPFL 635
Query: 702 QRFGVLLPNAMRMQLQGKLRQMTLGITDVWLRTDKDWKAGKTKIFLRDHQDTL-LEVQRS 760
+R+ LL + G R+ + + + GKTKIF+R + LE QR
Sbjct: 636 ERYR-LLSRSTWPHWNGGDREGVEKVLGELSMSSGELAFGKTKIFIRSPKTLFYLEEQRR 694
Query: 761 QVLDRAALSIQKVLRGYRYRKEFLRQRRAAVTLQAWWRGYCNRRNFKLILVGFERLQAIA 820
L + A IQK+ RG+R R + R++ + + +W+RG ++ + I +QA
Sbjct: 695 LRLQQLATLIQKIYRGWRCRTHYQLMRKSQILISSWFRGNMQKKCYGKIKASVLLIQAFV 754
Query: 821 RSQPLARQYQ 830
R + Y+
Sbjct: 755 RGWKARKNYR 764
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 79,311,656
Number of Sequences: 37866
Number of extensions: 3537205
Number of successful extensions: 8886
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 69
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 7978
Number of HSP's gapped (non-prelim): 343
length of query: 2116
length of database: 18,247,518
effective HSP length: 118
effective length of query: 1998
effective length of database: 13,779,330
effective search space: 27531101340
effective search space used: 27531101340
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.