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Search of human proteins with 122937472
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|122937472 bicaudal C homolog 1 [Homo sapiens]
(974 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|122937472 bicaudal C homolog 1 [Homo sapiens] 1925 0.0
gi|67906195 ankyrin repeat and sterile alpha motif domain contai... 79 2e-14
gi|4885409 high density lipoprotein binding protein [Homo sapiens] 77 8e-14
gi|42716280 high density lipoprotein binding protein [Homo sapiens] 77 8e-14
gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens] 68 4e-11
gi|42734375 ankyrin repeat and sterile alpha motif domain contai... 67 1e-10
gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens] 65 4e-10
gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens] 64 5e-10
gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens] 57 8e-08
gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens] 57 1e-07
gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens] 56 2e-07
gi|222352151 poly(rC) binding protein 1 [Homo sapiens] 54 5e-07
gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens] 54 9e-07
gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens] 53 1e-06
gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens] 53 2e-06
gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens] 53 2e-06
gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens] 50 1e-05
gi|161019170 mucin 5AC [Homo sapiens] 47 7e-05
gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 47 7e-05
gi|197276670 spermatogenesis and centriole associated 1 isoform ... 46 2e-04
gi|197276668 spermatogenesis and centriole associated 1 isoform ... 46 2e-04
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 45 3e-04
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] 45 4e-04
gi|91982772 mucin 17 [Homo sapiens] 45 4e-04
gi|21735419 zinc finger, CCHC domain containing 14 [Homo sapiens] 44 6e-04
gi|122937243 dual specificity phosphatase 27 [Homo sapiens] 43 0.001
gi|118600983 chondroitin sulfate proteoglycan 3 [Homo sapiens] 43 0.001
gi|147902746 MEX3A protein [Homo sapiens] 43 0.002
gi|56118219 insulin-like growth factor 2 mRNA binding protein 2 ... 42 0.003
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 42 0.003
>gi|122937472 bicaudal C homolog 1 [Homo sapiens]
Length = 974
Score = 1925 bits (4988), Expect = 0.0
Identities = 974/974 (100%), Positives = 974/974 (100%)
Query: 1 MAAQGEPGYLAAQSDPGSNSERSTDSPVPGSEDDLVAGATLHSPEWSEERFRVDRKKLEA 60
MAAQGEPGYLAAQSDPGSNSERSTDSPVPGSEDDLVAGATLHSPEWSEERFRVDRKKLEA
Sbjct: 1 MAAQGEPGYLAAQSDPGSNSERSTDSPVPGSEDDLVAGATLHSPEWSEERFRVDRKKLEA 60
Query: 61 MLQAAAEGKGRSGEDFFQKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKE 120
MLQAAAEGKGRSGEDFFQKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKE
Sbjct: 61 MLQAAAEGKGRSGEDFFQKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKE 120
Query: 121 MIMSVLDTKSNRVTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSNRNNQAEKS 180
MIMSVLDTKSNRVTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSNRNNQAEKS
Sbjct: 121 MIMSVLDTKSNRVTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSNRNNQAEKS 180
Query: 181 NQVSIAGQPAGVESARVRIRELLPLVLMFELPIAGILQPVPDPNSPSIQHISQTYNISVS 240
NQVSIAGQPAGVESARVRIRELLPLVLMFELPIAGILQPVPDPNSPSIQHISQTYNISVS
Sbjct: 181 NQVSIAGQPAGVESARVRIRELLPLVLMFELPIAGILQPVPDPNSPSIQHISQTYNISVS 240
Query: 241 FKQRSRMYGATVIVRGSQNNTSAVKEGTAMLLEHLAGSLASAIPVSTQLDIAAQHHLFMM 300
FKQRSRMYGATVIVRGSQNNTSAVKEGTAMLLEHLAGSLASAIPVSTQLDIAAQHHLFMM
Sbjct: 241 FKQRSRMYGATVIVRGSQNNTSAVKEGTAMLLEHLAGSLASAIPVSTQLDIAAQHHLFMM 300
Query: 301 GRNGSNIKHIMQRTGAQIHFPDPSNPQKKSTVYLQGTIESVCLARQYLMGCLPLVLMFDM 360
GRNGSNIKHIMQRTGAQIHFPDPSNPQKKSTVYLQGTIESVCLARQYLMGCLPLVLMFDM
Sbjct: 301 GRNGSNIKHIMQRTGAQIHFPDPSNPQKKSTVYLQGTIESVCLARQYLMGCLPLVLMFDM 360
Query: 361 KEEIEVDPQFIAQLMEQLDVFISIKPKPKQPSKSVIVKSVERNALNMYEARKCLLGLESS 420
KEEIEVDPQFIAQLMEQLDVFISIKPKPKQPSKSVIVKSVERNALNMYEARKCLLGLESS
Sbjct: 361 KEEIEVDPQFIAQLMEQLDVFISIKPKPKQPSKSVIVKSVERNALNMYEARKCLLGLESS 420
Query: 421 GVTIATSPSPASCPAGLACPSLDILASAGLGLTGLGLLGPTTLSLNTSTTPNSLLNALNS 480
GVTIATSPSPASCPAGLACPSLDILASAGLGLTGLGLLGPTTLSLNTSTTPNSLLNALNS
Sbjct: 421 GVTIATSPSPASCPAGLACPSLDILASAGLGLTGLGLLGPTTLSLNTSTTPNSLLNALNS 480
Query: 481 SVSPLQSPSSGTPSPTLWAPPLANTSSATGFSAIPHLMIPSTAQATLTNILLSGVPTYGH 540
SVSPLQSPSSGTPSPTLWAPPLANTSSATGFSAIPHLMIPSTAQATLTNILLSGVPTYGH
Sbjct: 481 SVSPLQSPSSGTPSPTLWAPPLANTSSATGFSAIPHLMIPSTAQATLTNILLSGVPTYGH 540
Query: 541 TAPSPPPGLTPVDVHINSMQTEGKKISAALNGHAQSPDIKYGAISTSSLGEKVLSANHGD 600
TAPSPPPGLTPVDVHINSMQTEGKKISAALNGHAQSPDIKYGAISTSSLGEKVLSANHGD
Sbjct: 541 TAPSPPPGLTPVDVHINSMQTEGKKISAALNGHAQSPDIKYGAISTSSLGEKVLSANHGD 600
Query: 601 PSIQTSGSEQTSPKSSPTEGCNDAFVEVGMPRSPSHSGNAGDLKQMMCPSKVSCAKRQTV 660
PSIQTSGSEQTSPKSSPTEGCNDAFVEVGMPRSPSHSGNAGDLKQMMCPSKVSCAKRQTV
Sbjct: 601 PSIQTSGSEQTSPKSSPTEGCNDAFVEVGMPRSPSHSGNAGDLKQMMCPSKVSCAKRQTV 660
Query: 661 ELLQGTKNSHLHSTDRLLSDPELSATESPLADKKAPGSERAAERAAAAQQNSERAHLAPR 720
ELLQGTKNSHLHSTDRLLSDPELSATESPLADKKAPGSERAAERAAAAQQNSERAHLAPR
Sbjct: 661 ELLQGTKNSHLHSTDRLLSDPELSATESPLADKKAPGSERAAERAAAAQQNSERAHLAPR 720
Query: 721 SSYVNMQAFDYEQKKLLATKAMLKKPVVTEVRTPTNTWSGLGFSKSMPAETIKELRRANH 780
SSYVNMQAFDYEQKKLLATKAMLKKPVVTEVRTPTNTWSGLGFSKSMPAETIKELRRANH
Sbjct: 721 SSYVNMQAFDYEQKKLLATKAMLKKPVVTEVRTPTNTWSGLGFSKSMPAETIKELRRANH 780
Query: 781 VSYKPTMTTTYEGSSMSLSRSNSREHLGGGSESDNWRDRNGIGPGSHSEFAASIGSPKRK 840
VSYKPTMTTTYEGSSMSLSRSNSREHLGGGSESDNWRDRNGIGPGSHSEFAASIGSPKRK
Sbjct: 781 VSYKPTMTTTYEGSSMSLSRSNSREHLGGGSESDNWRDRNGIGPGSHSEFAASIGSPKRK 840
Query: 841 QNKSTEHYLSSSNYMDCISSLTGSNGCNLNSSFKGSDLPELFSKLGLGKYTDVFQQQEID 900
QNKSTEHYLSSSNYMDCISSLTGSNGCNLNSSFKGSDLPELFSKLGLGKYTDVFQQQEID
Sbjct: 841 QNKSTEHYLSSSNYMDCISSLTGSNGCNLNSSFKGSDLPELFSKLGLGKYTDVFQQQEID 900
Query: 901 LQTFLTLTDQDLKELGITTFGARRKMLLAISELNKNRRKLFESPNARTSFLEGGASGRLP 960
LQTFLTLTDQDLKELGITTFGARRKMLLAISELNKNRRKLFESPNARTSFLEGGASGRLP
Sbjct: 901 LQTFLTLTDQDLKELGITTFGARRKMLLAISELNKNRRKLFESPNARTSFLEGGASGRLP 960
Query: 961 RQYHSDIASVSGRW 974
RQYHSDIASVSGRW
Sbjct: 961 RQYHSDIASVSGRW 974
>gi|67906195 ankyrin repeat and sterile alpha motif domain
containing 6 [Homo sapiens]
Length = 871
Score = 79.3 bits (194), Expect = 2e-14
Identities = 64/196 (32%), Positives = 96/196 (48%), Gaps = 15/196 (7%)
Query: 776 RRANHVSYKPTMTTTYEGSSMSLSRSNSREHLGGGSE------SDNWRDRNGIGPGSHSE 829
+ A + KP+ ++ G + S S GGS + R +G S S
Sbjct: 674 KAAGLLEQKPSHRSSPVGPAPGSSPSELPASPAGGSAPVGKKLETSKRPPSGTSTTSKST 733
Query: 830 FAASIGSPKRKQNKSTEHYLSSSNYMDCISSLTGSNGCNLNSSFKGSDLPELFSKLGLGK 889
SP K + + SSS++ SS S+G + +L + KL L K
Sbjct: 734 SPTLTPSPSPKGHTAESSVSSSSSHRQSKSSGGSSSGTITDED----ELTGILKKLSLEK 789
Query: 890 YTDVFQQQEIDLQTFLTLTDQDLKELGITTFGARRKMLLAISELN----KNRRKLFES-P 944
Y +F++QE+D++ FLTLTD DLKELGI T G+R+++L AISELN + R+ L E+
Sbjct: 790 YQPIFEEQEVDMEAFLTLTDGDLKELGIKTDGSRQQILAAISELNAGKGRERQILQETIH 849
Query: 945 NARTSFLEGGASGRLP 960
N +SF ++ R P
Sbjct: 850 NFHSSFESSASNTRAP 865
>gi|4885409 high density lipoprotein binding protein [Homo sapiens]
Length = 1268
Score = 77.0 bits (188), Expect = 8e-14
Identities = 88/423 (20%), Positives = 180/423 (42%), Gaps = 66/423 (15%)
Query: 29 PGSEDDLVAGATLHSPEWSEER-FRVD-RKKLEAMLQAAAEGKGRSGEDFFQKIMEETNT 86
P S+ + LH E + + F VD R K E +G G+ +K+ + T
Sbjct: 705 PSSDVEKAKKQLLHLAEEKQTKSFTVDIRAKPEYHKFLIGKGGGK-----IRKVRDSTGA 759
Query: 87 QIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLDTKSNRVTLKMDVSHTEHSH 146
++ +P+ A+ K I + GK++ V+EA++ + +++ N V M V H H
Sbjct: 760 RVIFPA-----AEDKDQDLITIIGKEDAVREAQKELEALIQNLDNVVEDSMLVDPKHHRH 814
Query: 147 VIGKGGNNIKKVMEE-TGCHIHFPDSNRNNQAEKSNQVSIAGQPAGVESARVRIRELL-- 203
+ + G ++++ EE G + FP S +S++V++ G VE+A+ RI+E++
Sbjct: 815 FVIRRGQVLREIAEEYGGVMVSFPRS-----GTQSDKVTLKGAKDCVEAAKKRIQEIIED 869
Query: 204 ---PLVLMFELPIAGILQPVPDPNSPSIQHISQTYNISVSF--KQRSRMYGATVIVRGSQ 258
+ L +P + V P IQ I++ +++ + F ++ + ++ +V+ +
Sbjct: 870 LEAQVTLECAIP-QKFHRSVMGPKGSRIQQITRDFSVQIKFPDREENAVHSTEPVVQENG 928
Query: 259 NNTSAVKE------------------GTAMLLEHLAGSLASAIPVSTQLDIAAQHHLFMM 300
+ +E G E +L + +PV+ ++++ H +++
Sbjct: 929 DEAGEGREAKDCDPGSPRRCDIIIISGRKEKCEAAKEALEALVPVTIEVEVPFDLHRYVI 988
Query: 301 GRNGSNIKHIMQRTGAQIHFPDPSNPQKKSTVYLQGTIESVCLARQYLMGCLPLV----- 355
G+ GS I+ +M IH P P + + + G ++ A+ L+ + +
Sbjct: 989 GQKGSGIRKMMDEFEVNIHVPAPE--LQSDIIAITGLAANLDRAKAGLLERVKELQAEQE 1046
Query: 356 --LMFDMKEEIEVDPQF-----------IAQLMEQLDVFISIKPKP--KQPSKSVIVKSV 400
+ K + VDP++ I Q+ + DV I K QP + +
Sbjct: 1047 DRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGY 1106
Query: 401 ERN 403
E+N
Sbjct: 1107 EKN 1109
Score = 71.6 bits (174), Expect = 3e-12
Identities = 64/230 (27%), Positives = 108/230 (46%), Gaps = 21/230 (9%)
Query: 100 SKKDPHIKVSGKKEDVKEA-KEMIMSVLDTKSNRVTLKMDVSHTEHSHVIGKGGNNIKKV 158
++K +++ G K +V++ K M V D N ++ + + H ++IGKGG NIKK+
Sbjct: 548 AQKSDIVQLRGPKNEVEKCTKYMQKMVADLVENSYSISVPIFKQFHKNIIGKGGANIKKI 607
Query: 159 MEETGCHIHFPDSNRNNQAEKSNQVSIAGQPAGVESARVRIREL---LPLVLMFELPI-A 214
EE+ I P N N S + I G+ A E+AR RI + L + E+ I A
Sbjct: 608 REESNTKIDLPAENSN-----SETIIITGKRANCEAARSRILSIQKDLANIAEVEVSIPA 662
Query: 215 GILQPVPDPNSPSIQHI-SQTYNISVSFKQRSRMYGATVIVRGSQNNTSAVKEGTAMLLE 273
+ + I+ I + + + F TV++RG ++ K+ L
Sbjct: 663 KLHNSLIGTKGRLIRSIMEECGGVHIHFPVEG-SGSDTVVIRGPSSDVEKAKK----QLL 717
Query: 274 HLAGSLASAIPVSTQLDIAA--QHHLFMMGRNGSNIKHIMQRTGAQIHFP 321
HLA + S +DI A ++H F++G+ G I+ + TGA++ FP
Sbjct: 718 HLAEEKQTK---SFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARVIFP 764
Score = 70.1 bits (170), Expect = 1e-11
Identities = 70/282 (24%), Positives = 127/282 (45%), Gaps = 30/282 (10%)
Query: 106 IKVSGKKEDVKEAKEMIMSVLDTKSNRVT-LKMDVSHTEHSHVIGKGGNNIKKVMEETGC 164
I + G EDV A+E I ++ NR+ +++++ H H H+IGK G NI ++ ++
Sbjct: 408 ITLEGPTEDVNVAQEQIEGMVKDLINRMDYVEINIDHKFHRHLIGKSGANINRIKDQYKV 467
Query: 165 HIHFPDSNRNNQAEKSNQVSIAGQPAGVESARVRIRELLPLVLMFELPIAGIL------- 217
+ P +EKSN + I G P GV+ A+ RELL L E L
Sbjct: 468 SVRIPP-----DSEKSNLIRIEGDPQGVQQAK---RELLELASRMENERTKDLIIEQRFH 519
Query: 218 QPVPDPNSPSIQHISQTY-NISVSFKQRSRMYGATVIVRGSQNNTSAVKEGTAMLLEHLA 276
+ + I+ I + + ++F ++ V +RG +N V++ T + + +A
Sbjct: 520 RTIIGQKGERIREIRDKFPEVIINFPDPAQK-SDIVQLRGPKNE---VEKCTKYMQKMVA 575
Query: 277 GSLASAIPVSTQLDIAAQHHLFMMGRNGSNIKHIMQRTGAQIHFPDPSNPQKKSTVYLQG 336
+ ++ +S + I Q H ++G+ G+NIK I + + +I P+ T+ + G
Sbjct: 576 DLVENSYSIS--VPIFKQFHKNIIGKGGANIKKIREESNTKIDL--PAENSNSETIIITG 631
Query: 337 TIESVCLARQYLMGCLPLVLMFDMKEEIEVDPQFIAQLMEQL 378
+ AR + L + D+ EV+ A+L L
Sbjct: 632 KRANCEAARSRI-----LSIQKDLANIAEVEVSIPAKLHNSL 668
Score = 68.6 bits (166), Expect = 3e-11
Identities = 74/342 (21%), Positives = 144/342 (42%), Gaps = 59/342 (17%)
Query: 106 IKVSGKKEDVKEAKEMIMSVLDTKSNR-VTLKMDVSHTEHSHVIGKGGNNIKKVMEETGC 164
+ + G DV++AK+ ++ + + K + T+ + H +IGKGG I+KV + TG
Sbjct: 700 VVIRGPSSDVEKAKKQLLHLAEEKQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGA 759
Query: 165 HIHFPDSNRNNQAEKSNQVSIAGQPAGVESARVRIRELLPLVLMFELPIAGILQPVPDPN 224
+ FP + +Q + ++I G+ V A+ +EL L+ + + + P +
Sbjct: 760 RVIFPAAEDKDQ----DLITIIGKEDAVREAQ---KELEALIQNLDNVVEDSMLVDPKHH 812
Query: 225 -------SPSIQHISQTY-NISVSFKQRSRMYGATVIVRGSQNNTSAVKEGTAMLLEHLA 276
++ I++ Y + VSF RS V ++G+++ A K+ ++E L
Sbjct: 813 RHFVIRRGQVLREIAEEYGGVMVSF-PRSGTQSDKVTLKGAKDCVEAAKKRIQEIIEDLE 871
Query: 277 GSLASAIPVSTQLDIAAQHHLFMMGRNGSNIKHIMQRTGAQIHFP--------------- 321
V+ + I + H +MG GS I+ I + QI FP
Sbjct: 872 AQ------VTLECAIPQKFHRSVMGPKGSRIQQITRDFSVQIKFPDREENAVHSTEPVVQ 925
Query: 322 ---------------DPSNPQKKSTVYLQGTIESVCLARQYLMGCLPLVL----MFDM-K 361
DP +P++ + + G E A++ L +P+ + FD+ +
Sbjct: 926 ENGDEAGEGREAKDCDPGSPRRCDIIIISGRKEKCEAAKEALEALVPVTIEVEVPFDLHR 985
Query: 362 EEIEVDPQFIAQLMEQLDVFISIKPKPKQPSKSVIVKSVERN 403
I I ++M++ +V I + P P+ S + + + N
Sbjct: 986 YVIGQKGSGIRKMMDEFEVNIHV-PAPELQSDIIAITGLAAN 1026
Score = 65.5 bits (158), Expect = 2e-10
Identities = 69/325 (21%), Positives = 144/325 (44%), Gaps = 54/325 (16%)
Query: 106 IKVSGKKEDVKEAKEMIMSVLDTKSNRVTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCH 165
I +SG+KE + AKE + +++ VT++++V H +VIG+ G+ I+K+M+E +
Sbjct: 951 IIISGRKEKCEAAKEALEALVP-----VTIEVEVPFDLHRYVIGQKGSGIRKMMDEFEVN 1005
Query: 166 IHFPDSNRNNQAEKSNQVSIAGQPAGVESARV----RIRELLP-----LVLMFELPIAGI 216
IH P +S+ ++I G A ++ A+ R++EL + F+L +
Sbjct: 1006 IHVPAPEL-----QSDIIAITGLAANLDRAKAGLLERVKELQAEQEDRALRSFKLSVT-- 1058
Query: 217 LQPVPDP-----NSPSIQHISQTYNISVSF--KQRSRMYGATVIVRGSQNNTSAVKEGTA 269
+ P P I I +++++ F K + + G + NT A ++
Sbjct: 1059 VDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAIL 1118
Query: 270 MLLEHLAGSLASAIPVSTQLDIAAQHHLFMMGRNGSNIKHIMQRTGAQIHFPDPSNPQKK 329
++ L ++ +P+ ++ H ++G G I+ IM I FP P
Sbjct: 1119 RIVGELEQMVSEDVPLDHRV------HARIIGARGKAIRKIMDEFKVDIRFPQSGAPD-P 1171
Query: 330 STVYLQGTIESVCLARQYLMGCLPLVLMFDMKEEIEVDPQFIAQLMEQLDVFISIKP--- 386
+ V + G E+V A ++ + ++ +++A +++ + + +KP
Sbjct: 1172 NCVTVTGLPENVEEAIDHI---------------LNLEEEYLADVVDSEALQVYMKPPAH 1216
Query: 387 -KPKQPSKSVIVKSVERNALNMYEA 410
+ K PS+ +V+ A + +A
Sbjct: 1217 EEAKAPSRGFVVRDAPWTASSSEKA 1241
Score = 59.3 bits (142), Expect = 2e-08
Identities = 54/274 (19%), Positives = 120/274 (43%), Gaps = 25/274 (9%)
Query: 79 KIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLDTKSNRVT-LKM 137
+IM+ET T+I P S I +G+KE + +A I + + K + T + +
Sbjct: 247 EIMQETGTRINIPPP------SVNRTEIVFTGEKEQLAQAVARIKKIYEEKKKKTTTIAV 300
Query: 138 DVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSNRNNQAEKSNQVSIAGQPAGVESARV 197
+V ++H +VIG GN++++++E TG + P S+ S V + G+P + A
Sbjct: 301 EVKKSQHKYVIGPKGNSLQEILERTGVSVEIPPSD-----SISETVILRGEPEKLGQALT 355
Query: 198 RIRELLPLVLMFELPIAGILQP-VPDPNSPSIQHISQTY-NISVSFKQRSRMYGATVIVR 255
+ + + L + ++ I+Q + + F + + +
Sbjct: 356 EVYAKANSFTVSSVAAPSWLHRFIIGKKGQNLAKITQQMPKVHIEFTEGE----DKITLE 411
Query: 256 GSQNNTSAVKEGTAMLLEHLAGSLASAIPVSTQLDIAAQHHLFMMGRNGSNIKHIMQRTG 315
G + + +E +++ L + +++I + H ++G++G+NI I +
Sbjct: 412 GPTEDVNVAQEQIEGMVKDLINRMD-----YVEINIDHKFHRHLIGKSGANINRIKDQYK 466
Query: 316 AQIHFPDPSNPQKKSTVYLQGTIESVCLARQYLM 349
+ P S +K + + ++G + V A++ L+
Sbjct: 467 VSVRIPPDS--EKSNLIRIEGDPQGVQQAKRELL 498
Score = 58.9 bits (141), Expect = 2e-08
Identities = 68/284 (23%), Positives = 123/284 (43%), Gaps = 27/284 (9%)
Query: 70 GRSGEDFFQKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLDTK 129
G+ G + +KI EE+NT+I P A++ I ++GK+ + + A+ I+S+
Sbjct: 598 GKGGANI-KKIREESNTKIDLP------AENSNSETIIITGKRANCEAARSRILSIQKDL 650
Query: 130 SNRVTLKMDVSHTEHSHVIGKGGNNIKKVMEET-GCHIHFPDSNRNNQAEKSNQVSIAGQ 188
+N +++ + H+ +IG G I+ +MEE G HIHFP + S+ V I G
Sbjct: 651 ANIAEVEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHFP-----VEGSGSDTVVIRGP 705
Query: 189 PAGVESARVRIRELLPLVLMFELPIAGILQP-----VPDPNSPSIQHISQTYNISVSFKQ 243
+ VE A+ ++ L + +P + I+ + + V F
Sbjct: 706 SSDVEKAKKQLLHLAEEKQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARVIFPA 765
Query: 244 RSRMYGATVIVRGSQNNTSAVKEGTAMLLEHLAGSLASAIPVSTQLDIAAQHHLFMMGRN 303
+ + G ++ AV+E LE L +L + + S +D +HH + R
Sbjct: 766 AEDKDQDLITIIGKED---AVREAQKE-LEALIQNLDNVVEDSMLVD--PKHHRHFVIRR 819
Query: 304 GSNIKHIMQR-TGAQIHFPDPSNPQKKSTVYLQGTIESVCLARQ 346
G ++ I + G + FP K T L+G + V A++
Sbjct: 820 GQVLREIAEEYGGVMVSFPRSGTQSDKVT--LKGAKDCVEAAKK 861
Score = 58.2 bits (139), Expect = 4e-08
Identities = 57/269 (21%), Positives = 111/269 (41%), Gaps = 33/269 (12%)
Query: 94 LKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLDTKSNRVTLKMDVSHTEHSHVIGKGGN 153
++I S+K I++ G + V++AK ++ + N T + + H +IG+ G
Sbjct: 469 VRIPPDSEKSNLIRIEGDPQGVQQAKRELLELASRMENERTKDLIIEQRFHRTIIGQKGE 528
Query: 154 NIKKVMEE-TGCHIHFPDSNRNNQAEKSNQVSIAGQPAGVESARVRIREL---------- 202
I+++ ++ I+FPD A+KS+ V + G VE ++++
Sbjct: 529 RIREIRDKFPEVIINFPD-----PAQKSDIVQLRGPKNEVEKCTKYMQKMVADLVENSYS 583
Query: 203 --LPLVLMFELPIAGILQPVPDPNSPSIQHISQTYNISVSFKQRSRMYGATVIVRGSQNN 260
+P+ F I G +I+ I + N + + T+I+ G + N
Sbjct: 584 ISVPIFKQFHKNIIG-------KGGANIKKIREESNTKIDLPAEN-SNSETIIITGKRAN 635
Query: 261 TSAVKEGTAMLLEHLAGSLASAIPVSTQLDIAAQHHLFMMGRNGSNIKHIMQRTGAQIHF 320
A + + + LA ++ I A+ H ++G G I+ IM+ G +H
Sbjct: 636 CEAARSRILSIQKDLANI------AEVEVSIPAKLHNSLIGTKGRLIRSIMEECGG-VHI 688
Query: 321 PDPSNPQKKSTVYLQGTIESVCLARQYLM 349
P TV ++G V A++ L+
Sbjct: 689 HFPVEGSGSDTVVIRGPSSDVEKAKKQLL 717
Score = 54.7 bits (130), Expect = 4e-07
Identities = 61/247 (24%), Positives = 104/247 (42%), Gaps = 34/247 (13%)
Query: 106 IKVSGKKEDVKEAKEMIMSVLDTKSNRVTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCH 165
I VSGK + V +A++ I++ L T+++ T+ + H H VIGK G ++ + +T
Sbjct: 127 IMVSGKLDAVMKARKDIVARLQTQAS-ATVAIPKEH--HRFVIGKNGEKLQDLELKTATK 183
Query: 166 IHFPDSNRNNQAEKSNQVSIAGQPAGVESAR-----------VRIRELLPLVLMFELPIA 214
I P + + SNQ+ I G G+E AR R E L + F IA
Sbjct: 184 IQIPRPD-----DPSNQIKITGTKEGIEKARHEVLLISAEQDKRAVERLEVEKAFHPFIA 238
Query: 215 GILQPVPDPNSPSIQHISQTYNISVSFKQRSRMYGATVIVRGSQNNTSAVKEGTAMLLEH 274
G P + + I Q ++ S V + AV + E
Sbjct: 239 G-------PYNRLVGEIMQETGTRINIPPPSVNRTEIVFTGEKEQLAQAVARIKKIYEEK 291
Query: 275 LAGSLASAIPVSTQLDIAAQHHLFMMGRNGSNIKHIMQRTGAQIHFPDPSNPQKKSTVYL 334
+ A+ ++ H +++G G++++ I++RTG + P PS+ TV L
Sbjct: 292 KKKTTTIAV------EVKKSQHKYVIGPKGNSLQEILERTGVSVEIP-PSD-SISETVIL 343
Query: 335 QGTIESV 341
+G E +
Sbjct: 344 RGEPEKL 350
Score = 51.2 bits (121), Expect = 5e-06
Identities = 35/126 (27%), Positives = 60/126 (47%), Gaps = 8/126 (6%)
Query: 70 GRSGEDFFQKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLDTK 129
GR G Q I E + I +P K ++ I ++G +++ + A++ I+ ++
Sbjct: 1069 GRKGAVITQ-IRLEHDVNIQFPDK---DDGNQPQDQITITGYEKNTEAARDAILRIVGEL 1124
Query: 130 SNRVTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSNRNNQAEKSNQVSIAGQP 189
V+ + + H H+ +IG G I+K+M+E I FP S A N V++ G P
Sbjct: 1125 EQMVSEDVPLDHRVHARIIGARGKAIRKIMDEFKVDIRFPQSG----APDPNCVTVTGLP 1180
Query: 190 AGVESA 195
VE A
Sbjct: 1181 ENVEEA 1186
Score = 41.2 bits (95), Expect = 0.005
Identities = 35/154 (22%), Positives = 67/154 (43%), Gaps = 20/154 (12%)
Query: 286 STQLDIAAQHHLFMMGRNGSNIKHIMQRTGAQIHFPDPSNPQKKSTVYLQGTIESVCLAR 345
S + I +HH F++G+NG ++ + +T +I P P +P + + + GT E + AR
Sbjct: 152 SATVAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSNQ--IKITGTKEGIEKAR 209
Query: 346 QYLMGCLPLVLMFDMK---EEIEVDPQF-----------IAQLMEQLDVFISIKPKPKQP 391
++ L+ K E +EV+ F + ++M++ I+I P
Sbjct: 210 HEVL----LISAEQDKRAVERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIPPPSVNR 265
Query: 392 SKSVIVKSVERNALNMYEARKCLLGLESSGVTIA 425
++ V E+ A + +K + TIA
Sbjct: 266 TEIVFTGEKEQLAQAVARIKKIYEEKKKKTTTIA 299
Score = 40.0 bits (92), Expect = 0.011
Identities = 76/367 (20%), Positives = 148/367 (40%), Gaps = 50/367 (13%)
Query: 78 QKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLDTKSNRVTLKM 137
Q+I+E T + P I + + G+ E + +A ++ + K+N T+
Sbjct: 319 QEILERTGVSVEIPPSDSISET------VILRGEPEKLGQA----LTEVYAKANSFTVSS 368
Query: 138 DVSHTE-HSHVIGKGGNNIKKVMEE-TGCHIHFPDSNRNNQAEKSNQVSIAGQPAGVESA 195
+ + H +IGK G N+ K+ ++ HI F E +++++ G V A
Sbjct: 369 VAAPSWLHRFIIGKKGQNLAKITQQMPKVHIEF--------TEGEDKITLEGPTEDVNVA 420
Query: 196 RVRI----RELLPLVLMFELPI-AGILQPVPDPNSPSIQHISQTYNISVSFKQRSRMYGA 250
+ +I ++L+ + E+ I + + + +I I Y +SV S
Sbjct: 421 QEQIEGMVKDLINRMDYVEINIDHKFHRHLIGKSGANINRIKDQYKVSVRIPPDSEKSNL 480
Query: 251 TVIVRGSQNNTSAVKEGTAMLLEHLAGSLASAIPVSTQLDIAAQHHLFMMGRNGSNIKHI 310
I + + V++ LLE LA + + + L I + H ++G+ G I+ I
Sbjct: 481 IRI----EGDPQGVQQAKRELLE-LASRMEN--ERTKDLIIEQRFHRTIIGQKGERIREI 533
Query: 311 MQR-TGAQIHFPDPSNPQKKSTVYLQGTIESVCLARQYLMGCLPLVLMFDMKEEIEVDPQ 369
+ I+FPDP+ QK V L+G V +Y+ + ++ + + Q
Sbjct: 534 RDKFPEVIINFPDPA--QKSDIVQLRGPKNEVEKCTKYMQKMVADLVENSYSISVPIFKQ 591
Query: 370 F-----------IAQLMEQLDVFISIKPKPKQPSKSVIVKSVERNALNMYEARKCLLGLE 418
F I ++ E+ + I + P S+++I+ N AR +L ++
Sbjct: 592 FHKNIIGKGGANIKKIREESNTKIDL-PAENSNSETIIITG---KRANCEAARSRILSIQ 647
Query: 419 SSGVTIA 425
IA
Sbjct: 648 KDLANIA 654
>gi|42716280 high density lipoprotein binding protein [Homo sapiens]
Length = 1268
Score = 77.0 bits (188), Expect = 8e-14
Identities = 88/423 (20%), Positives = 180/423 (42%), Gaps = 66/423 (15%)
Query: 29 PGSEDDLVAGATLHSPEWSEER-FRVD-RKKLEAMLQAAAEGKGRSGEDFFQKIMEETNT 86
P S+ + LH E + + F VD R K E +G G+ +K+ + T
Sbjct: 705 PSSDVEKAKKQLLHLAEEKQTKSFTVDIRAKPEYHKFLIGKGGGK-----IRKVRDSTGA 759
Query: 87 QIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLDTKSNRVTLKMDVSHTEHSH 146
++ +P+ A+ K I + GK++ V+EA++ + +++ N V M V H H
Sbjct: 760 RVIFPA-----AEDKDQDLITIIGKEDAVREAQKELEALIQNLDNVVEDSMLVDPKHHRH 814
Query: 147 VIGKGGNNIKKVMEE-TGCHIHFPDSNRNNQAEKSNQVSIAGQPAGVESARVRIRELL-- 203
+ + G ++++ EE G + FP S +S++V++ G VE+A+ RI+E++
Sbjct: 815 FVIRRGQVLREIAEEYGGVMVSFPRS-----GTQSDKVTLKGAKDCVEAAKKRIQEIIED 869
Query: 204 ---PLVLMFELPIAGILQPVPDPNSPSIQHISQTYNISVSF--KQRSRMYGATVIVRGSQ 258
+ L +P + V P IQ I++ +++ + F ++ + ++ +V+ +
Sbjct: 870 LEAQVTLECAIP-QKFHRSVMGPKGSRIQQITRDFSVQIKFPDREENAVHSTEPVVQENG 928
Query: 259 NNTSAVKE------------------GTAMLLEHLAGSLASAIPVSTQLDIAAQHHLFMM 300
+ +E G E +L + +PV+ ++++ H +++
Sbjct: 929 DEAGEGREAKDCDPGSPRRCDIIIISGRKEKCEAAKEALEALVPVTIEVEVPFDLHRYVI 988
Query: 301 GRNGSNIKHIMQRTGAQIHFPDPSNPQKKSTVYLQGTIESVCLARQYLMGCLPLV----- 355
G+ GS I+ +M IH P P + + + G ++ A+ L+ + +
Sbjct: 989 GQKGSGIRKMMDEFEVNIHVPAPE--LQSDIIAITGLAANLDRAKAGLLERVKELQAEQE 1046
Query: 356 --LMFDMKEEIEVDPQF-----------IAQLMEQLDVFISIKPKP--KQPSKSVIVKSV 400
+ K + VDP++ I Q+ + DV I K QP + +
Sbjct: 1047 DRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGY 1106
Query: 401 ERN 403
E+N
Sbjct: 1107 EKN 1109
Score = 71.6 bits (174), Expect = 3e-12
Identities = 64/230 (27%), Positives = 108/230 (46%), Gaps = 21/230 (9%)
Query: 100 SKKDPHIKVSGKKEDVKEA-KEMIMSVLDTKSNRVTLKMDVSHTEHSHVIGKGGNNIKKV 158
++K +++ G K +V++ K M V D N ++ + + H ++IGKGG NIKK+
Sbjct: 548 AQKSDIVQLRGPKNEVEKCTKYMQKMVADLVENSYSISVPIFKQFHKNIIGKGGANIKKI 607
Query: 159 MEETGCHIHFPDSNRNNQAEKSNQVSIAGQPAGVESARVRIREL---LPLVLMFELPI-A 214
EE+ I P N N S + I G+ A E+AR RI + L + E+ I A
Sbjct: 608 REESNTKIDLPAENSN-----SETIIITGKRANCEAARSRILSIQKDLANIAEVEVSIPA 662
Query: 215 GILQPVPDPNSPSIQHI-SQTYNISVSFKQRSRMYGATVIVRGSQNNTSAVKEGTAMLLE 273
+ + I+ I + + + F TV++RG ++ K+ L
Sbjct: 663 KLHNSLIGTKGRLIRSIMEECGGVHIHFPVEG-SGSDTVVIRGPSSDVEKAKK----QLL 717
Query: 274 HLAGSLASAIPVSTQLDIAA--QHHLFMMGRNGSNIKHIMQRTGAQIHFP 321
HLA + S +DI A ++H F++G+ G I+ + TGA++ FP
Sbjct: 718 HLAEEKQTK---SFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARVIFP 764
Score = 70.1 bits (170), Expect = 1e-11
Identities = 70/282 (24%), Positives = 127/282 (45%), Gaps = 30/282 (10%)
Query: 106 IKVSGKKEDVKEAKEMIMSVLDTKSNRVT-LKMDVSHTEHSHVIGKGGNNIKKVMEETGC 164
I + G EDV A+E I ++ NR+ +++++ H H H+IGK G NI ++ ++
Sbjct: 408 ITLEGPTEDVNVAQEQIEGMVKDLINRMDYVEINIDHKFHRHLIGKSGANINRIKDQYKV 467
Query: 165 HIHFPDSNRNNQAEKSNQVSIAGQPAGVESARVRIRELLPLVLMFELPIAGIL------- 217
+ P +EKSN + I G P GV+ A+ RELL L E L
Sbjct: 468 SVRIPP-----DSEKSNLIRIEGDPQGVQQAK---RELLELASRMENERTKDLIIEQRFH 519
Query: 218 QPVPDPNSPSIQHISQTY-NISVSFKQRSRMYGATVIVRGSQNNTSAVKEGTAMLLEHLA 276
+ + I+ I + + ++F ++ V +RG +N V++ T + + +A
Sbjct: 520 RTIIGQKGERIREIRDKFPEVIINFPDPAQK-SDIVQLRGPKNE---VEKCTKYMQKMVA 575
Query: 277 GSLASAIPVSTQLDIAAQHHLFMMGRNGSNIKHIMQRTGAQIHFPDPSNPQKKSTVYLQG 336
+ ++ +S + I Q H ++G+ G+NIK I + + +I P+ T+ + G
Sbjct: 576 DLVENSYSIS--VPIFKQFHKNIIGKGGANIKKIREESNTKIDL--PAENSNSETIIITG 631
Query: 337 TIESVCLARQYLMGCLPLVLMFDMKEEIEVDPQFIAQLMEQL 378
+ AR + L + D+ EV+ A+L L
Sbjct: 632 KRANCEAARSRI-----LSIQKDLANIAEVEVSIPAKLHNSL 668
Score = 68.6 bits (166), Expect = 3e-11
Identities = 74/342 (21%), Positives = 144/342 (42%), Gaps = 59/342 (17%)
Query: 106 IKVSGKKEDVKEAKEMIMSVLDTKSNR-VTLKMDVSHTEHSHVIGKGGNNIKKVMEETGC 164
+ + G DV++AK+ ++ + + K + T+ + H +IGKGG I+KV + TG
Sbjct: 700 VVIRGPSSDVEKAKKQLLHLAEEKQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGA 759
Query: 165 HIHFPDSNRNNQAEKSNQVSIAGQPAGVESARVRIRELLPLVLMFELPIAGILQPVPDPN 224
+ FP + +Q + ++I G+ V A+ +EL L+ + + + P +
Sbjct: 760 RVIFPAAEDKDQ----DLITIIGKEDAVREAQ---KELEALIQNLDNVVEDSMLVDPKHH 812
Query: 225 -------SPSIQHISQTY-NISVSFKQRSRMYGATVIVRGSQNNTSAVKEGTAMLLEHLA 276
++ I++ Y + VSF RS V ++G+++ A K+ ++E L
Sbjct: 813 RHFVIRRGQVLREIAEEYGGVMVSF-PRSGTQSDKVTLKGAKDCVEAAKKRIQEIIEDLE 871
Query: 277 GSLASAIPVSTQLDIAAQHHLFMMGRNGSNIKHIMQRTGAQIHFP--------------- 321
V+ + I + H +MG GS I+ I + QI FP
Sbjct: 872 AQ------VTLECAIPQKFHRSVMGPKGSRIQQITRDFSVQIKFPDREENAVHSTEPVVQ 925
Query: 322 ---------------DPSNPQKKSTVYLQGTIESVCLARQYLMGCLPLVL----MFDM-K 361
DP +P++ + + G E A++ L +P+ + FD+ +
Sbjct: 926 ENGDEAGEGREAKDCDPGSPRRCDIIIISGRKEKCEAAKEALEALVPVTIEVEVPFDLHR 985
Query: 362 EEIEVDPQFIAQLMEQLDVFISIKPKPKQPSKSVIVKSVERN 403
I I ++M++ +V I + P P+ S + + + N
Sbjct: 986 YVIGQKGSGIRKMMDEFEVNIHV-PAPELQSDIIAITGLAAN 1026
Score = 65.5 bits (158), Expect = 2e-10
Identities = 69/325 (21%), Positives = 144/325 (44%), Gaps = 54/325 (16%)
Query: 106 IKVSGKKEDVKEAKEMIMSVLDTKSNRVTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCH 165
I +SG+KE + AKE + +++ VT++++V H +VIG+ G+ I+K+M+E +
Sbjct: 951 IIISGRKEKCEAAKEALEALVP-----VTIEVEVPFDLHRYVIGQKGSGIRKMMDEFEVN 1005
Query: 166 IHFPDSNRNNQAEKSNQVSIAGQPAGVESARV----RIRELLP-----LVLMFELPIAGI 216
IH P +S+ ++I G A ++ A+ R++EL + F+L +
Sbjct: 1006 IHVPAPEL-----QSDIIAITGLAANLDRAKAGLLERVKELQAEQEDRALRSFKLSVT-- 1058
Query: 217 LQPVPDP-----NSPSIQHISQTYNISVSF--KQRSRMYGATVIVRGSQNNTSAVKEGTA 269
+ P P I I +++++ F K + + G + NT A ++
Sbjct: 1059 VDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAIL 1118
Query: 270 MLLEHLAGSLASAIPVSTQLDIAAQHHLFMMGRNGSNIKHIMQRTGAQIHFPDPSNPQKK 329
++ L ++ +P+ ++ H ++G G I+ IM I FP P
Sbjct: 1119 RIVGELEQMVSEDVPLDHRV------HARIIGARGKAIRKIMDEFKVDIRFPQSGAPD-P 1171
Query: 330 STVYLQGTIESVCLARQYLMGCLPLVLMFDMKEEIEVDPQFIAQLMEQLDVFISIKP--- 386
+ V + G E+V A ++ + ++ +++A +++ + + +KP
Sbjct: 1172 NCVTVTGLPENVEEAIDHI---------------LNLEEEYLADVVDSEALQVYMKPPAH 1216
Query: 387 -KPKQPSKSVIVKSVERNALNMYEA 410
+ K PS+ +V+ A + +A
Sbjct: 1217 EEAKAPSRGFVVRDAPWTASSSEKA 1241
Score = 59.3 bits (142), Expect = 2e-08
Identities = 54/274 (19%), Positives = 120/274 (43%), Gaps = 25/274 (9%)
Query: 79 KIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLDTKSNRVT-LKM 137
+IM+ET T+I P S I +G+KE + +A I + + K + T + +
Sbjct: 247 EIMQETGTRINIPPP------SVNRTEIVFTGEKEQLAQAVARIKKIYEEKKKKTTTIAV 300
Query: 138 DVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSNRNNQAEKSNQVSIAGQPAGVESARV 197
+V ++H +VIG GN++++++E TG + P S+ S V + G+P + A
Sbjct: 301 EVKKSQHKYVIGPKGNSLQEILERTGVSVEIPPSD-----SISETVILRGEPEKLGQALT 355
Query: 198 RIRELLPLVLMFELPIAGILQP-VPDPNSPSIQHISQTY-NISVSFKQRSRMYGATVIVR 255
+ + + L + ++ I+Q + + F + + +
Sbjct: 356 EVYAKANSFTVSSVAAPSWLHRFIIGKKGQNLAKITQQMPKVHIEFTEGE----DKITLE 411
Query: 256 GSQNNTSAVKEGTAMLLEHLAGSLASAIPVSTQLDIAAQHHLFMMGRNGSNIKHIMQRTG 315
G + + +E +++ L + +++I + H ++G++G+NI I +
Sbjct: 412 GPTEDVNVAQEQIEGMVKDLINRMD-----YVEINIDHKFHRHLIGKSGANINRIKDQYK 466
Query: 316 AQIHFPDPSNPQKKSTVYLQGTIESVCLARQYLM 349
+ P S +K + + ++G + V A++ L+
Sbjct: 467 VSVRIPPDS--EKSNLIRIEGDPQGVQQAKRELL 498
Score = 58.9 bits (141), Expect = 2e-08
Identities = 68/284 (23%), Positives = 123/284 (43%), Gaps = 27/284 (9%)
Query: 70 GRSGEDFFQKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLDTK 129
G+ G + +KI EE+NT+I P A++ I ++GK+ + + A+ I+S+
Sbjct: 598 GKGGANI-KKIREESNTKIDLP------AENSNSETIIITGKRANCEAARSRILSIQKDL 650
Query: 130 SNRVTLKMDVSHTEHSHVIGKGGNNIKKVMEET-GCHIHFPDSNRNNQAEKSNQVSIAGQ 188
+N +++ + H+ +IG G I+ +MEE G HIHFP + S+ V I G
Sbjct: 651 ANIAEVEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHFP-----VEGSGSDTVVIRGP 705
Query: 189 PAGVESARVRIRELLPLVLMFELPIAGILQP-----VPDPNSPSIQHISQTYNISVSFKQ 243
+ VE A+ ++ L + +P + I+ + + V F
Sbjct: 706 SSDVEKAKKQLLHLAEEKQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARVIFPA 765
Query: 244 RSRMYGATVIVRGSQNNTSAVKEGTAMLLEHLAGSLASAIPVSTQLDIAAQHHLFMMGRN 303
+ + G ++ AV+E LE L +L + + S +D +HH + R
Sbjct: 766 AEDKDQDLITIIGKED---AVREAQKE-LEALIQNLDNVVEDSMLVD--PKHHRHFVIRR 819
Query: 304 GSNIKHIMQR-TGAQIHFPDPSNPQKKSTVYLQGTIESVCLARQ 346
G ++ I + G + FP K T L+G + V A++
Sbjct: 820 GQVLREIAEEYGGVMVSFPRSGTQSDKVT--LKGAKDCVEAAKK 861
Score = 58.2 bits (139), Expect = 4e-08
Identities = 57/269 (21%), Positives = 111/269 (41%), Gaps = 33/269 (12%)
Query: 94 LKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLDTKSNRVTLKMDVSHTEHSHVIGKGGN 153
++I S+K I++ G + V++AK ++ + N T + + H +IG+ G
Sbjct: 469 VRIPPDSEKSNLIRIEGDPQGVQQAKRELLELASRMENERTKDLIIEQRFHRTIIGQKGE 528
Query: 154 NIKKVMEE-TGCHIHFPDSNRNNQAEKSNQVSIAGQPAGVESARVRIREL---------- 202
I+++ ++ I+FPD A+KS+ V + G VE ++++
Sbjct: 529 RIREIRDKFPEVIINFPD-----PAQKSDIVQLRGPKNEVEKCTKYMQKMVADLVENSYS 583
Query: 203 --LPLVLMFELPIAGILQPVPDPNSPSIQHISQTYNISVSFKQRSRMYGATVIVRGSQNN 260
+P+ F I G +I+ I + N + + T+I+ G + N
Sbjct: 584 ISVPIFKQFHKNIIG-------KGGANIKKIREESNTKIDLPAEN-SNSETIIITGKRAN 635
Query: 261 TSAVKEGTAMLLEHLAGSLASAIPVSTQLDIAAQHHLFMMGRNGSNIKHIMQRTGAQIHF 320
A + + + LA ++ I A+ H ++G G I+ IM+ G +H
Sbjct: 636 CEAARSRILSIQKDLANI------AEVEVSIPAKLHNSLIGTKGRLIRSIMEECGG-VHI 688
Query: 321 PDPSNPQKKSTVYLQGTIESVCLARQYLM 349
P TV ++G V A++ L+
Sbjct: 689 HFPVEGSGSDTVVIRGPSSDVEKAKKQLL 717
Score = 54.7 bits (130), Expect = 4e-07
Identities = 61/247 (24%), Positives = 104/247 (42%), Gaps = 34/247 (13%)
Query: 106 IKVSGKKEDVKEAKEMIMSVLDTKSNRVTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCH 165
I VSGK + V +A++ I++ L T+++ T+ + H H VIGK G ++ + +T
Sbjct: 127 IMVSGKLDAVMKARKDIVARLQTQAS-ATVAIPKEH--HRFVIGKNGEKLQDLELKTATK 183
Query: 166 IHFPDSNRNNQAEKSNQVSIAGQPAGVESAR-----------VRIRELLPLVLMFELPIA 214
I P + + SNQ+ I G G+E AR R E L + F IA
Sbjct: 184 IQIPRPD-----DPSNQIKITGTKEGIEKARHEVLLISAEQDKRAVERLEVEKAFHPFIA 238
Query: 215 GILQPVPDPNSPSIQHISQTYNISVSFKQRSRMYGATVIVRGSQNNTSAVKEGTAMLLEH 274
G P + + I Q ++ S V + AV + E
Sbjct: 239 G-------PYNRLVGEIMQETGTRINIPPPSVNRTEIVFTGEKEQLAQAVARIKKIYEEK 291
Query: 275 LAGSLASAIPVSTQLDIAAQHHLFMMGRNGSNIKHIMQRTGAQIHFPDPSNPQKKSTVYL 334
+ A+ ++ H +++G G++++ I++RTG + P PS+ TV L
Sbjct: 292 KKKTTTIAV------EVKKSQHKYVIGPKGNSLQEILERTGVSVEIP-PSD-SISETVIL 343
Query: 335 QGTIESV 341
+G E +
Sbjct: 344 RGEPEKL 350
Score = 51.2 bits (121), Expect = 5e-06
Identities = 35/126 (27%), Positives = 60/126 (47%), Gaps = 8/126 (6%)
Query: 70 GRSGEDFFQKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLDTK 129
GR G Q I E + I +P K ++ I ++G +++ + A++ I+ ++
Sbjct: 1069 GRKGAVITQ-IRLEHDVNIQFPDK---DDGNQPQDQITITGYEKNTEAARDAILRIVGEL 1124
Query: 130 SNRVTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSNRNNQAEKSNQVSIAGQP 189
V+ + + H H+ +IG G I+K+M+E I FP S A N V++ G P
Sbjct: 1125 EQMVSEDVPLDHRVHARIIGARGKAIRKIMDEFKVDIRFPQSG----APDPNCVTVTGLP 1180
Query: 190 AGVESA 195
VE A
Sbjct: 1181 ENVEEA 1186
Score = 41.2 bits (95), Expect = 0.005
Identities = 35/154 (22%), Positives = 67/154 (43%), Gaps = 20/154 (12%)
Query: 286 STQLDIAAQHHLFMMGRNGSNIKHIMQRTGAQIHFPDPSNPQKKSTVYLQGTIESVCLAR 345
S + I +HH F++G+NG ++ + +T +I P P +P + + + GT E + AR
Sbjct: 152 SATVAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSNQ--IKITGTKEGIEKAR 209
Query: 346 QYLMGCLPLVLMFDMK---EEIEVDPQF-----------IAQLMEQLDVFISIKPKPKQP 391
++ L+ K E +EV+ F + ++M++ I+I P
Sbjct: 210 HEVL----LISAEQDKRAVERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIPPPSVNR 265
Query: 392 SKSVIVKSVERNALNMYEARKCLLGLESSGVTIA 425
++ V E+ A + +K + TIA
Sbjct: 266 TEIVFTGEKEQLAQAVARIKKIYEEKKKKTTTIA 299
Score = 40.0 bits (92), Expect = 0.011
Identities = 76/367 (20%), Positives = 148/367 (40%), Gaps = 50/367 (13%)
Query: 78 QKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLDTKSNRVTLKM 137
Q+I+E T + P I + + G+ E + +A ++ + K+N T+
Sbjct: 319 QEILERTGVSVEIPPSDSISET------VILRGEPEKLGQA----LTEVYAKANSFTVSS 368
Query: 138 DVSHTE-HSHVIGKGGNNIKKVMEE-TGCHIHFPDSNRNNQAEKSNQVSIAGQPAGVESA 195
+ + H +IGK G N+ K+ ++ HI F E +++++ G V A
Sbjct: 369 VAAPSWLHRFIIGKKGQNLAKITQQMPKVHIEF--------TEGEDKITLEGPTEDVNVA 420
Query: 196 RVRI----RELLPLVLMFELPI-AGILQPVPDPNSPSIQHISQTYNISVSFKQRSRMYGA 250
+ +I ++L+ + E+ I + + + +I I Y +SV S
Sbjct: 421 QEQIEGMVKDLINRMDYVEINIDHKFHRHLIGKSGANINRIKDQYKVSVRIPPDSEKSNL 480
Query: 251 TVIVRGSQNNTSAVKEGTAMLLEHLAGSLASAIPVSTQLDIAAQHHLFMMGRNGSNIKHI 310
I + + V++ LLE LA + + + L I + H ++G+ G I+ I
Sbjct: 481 IRI----EGDPQGVQQAKRELLE-LASRMEN--ERTKDLIIEQRFHRTIIGQKGERIREI 533
Query: 311 MQR-TGAQIHFPDPSNPQKKSTVYLQGTIESVCLARQYLMGCLPLVLMFDMKEEIEVDPQ 369
+ I+FPDP+ QK V L+G V +Y+ + ++ + + Q
Sbjct: 534 RDKFPEVIINFPDPA--QKSDIVQLRGPKNEVEKCTKYMQKMVADLVENSYSISVPIFKQ 591
Query: 370 F-----------IAQLMEQLDVFISIKPKPKQPSKSVIVKSVERNALNMYEARKCLLGLE 418
F I ++ E+ + I + P S+++I+ N AR +L ++
Sbjct: 592 FHKNIIGKGGANIKKIREESNTKIDL-PAENSNSETIIITG---KRANCEAARSRILSIQ 647
Query: 419 SSGVTIA 425
IA
Sbjct: 648 KDLANIA 654
>gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens]
Length = 331
Score = 68.2 bits (165), Expect = 4e-11
Identities = 80/303 (26%), Positives = 131/303 (43%), Gaps = 38/303 (12%)
Query: 70 GRSGEDFFQKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLD-- 127
G+ GE +K+ EE+ +I I + + I ++G + +A MI+ L+
Sbjct: 30 GKKGESV-KKMREESGARI------NISEGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82
Query: 128 --------TKSNR--VTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSNRNNQA 177
T ++R VTL++ V ++ +IGKGG IK++ E TG + N
Sbjct: 83 ISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNST 142
Query: 178 EKSNQVSIAGQPAGVESARVRIRELLPLVLMFELPIAGILQPV-PDPNS-PSIQHISQTY 235
E++ ++IAG P + +I V+M E P G+ P P P+S P I Q Y
Sbjct: 143 ERA--ITIAGIPQSIIECVKQI-----CVVMLESPPKGVTIPYRPKPSSSPVIFAGGQAY 195
Query: 236 NISVSFK---------QRSRMYGATVIVRGSQNNTSAVKEGTAMLLEHLAGSLASAIPVS 286
I + + M + + S ++ + + + AG ASA S
Sbjct: 196 TIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTS 255
Query: 287 TQLDIAAQHHLFMMGRNGSNIKHIMQRTGAQIHFPDPSNPQKKSTVYLQGTIESVCLARQ 346
+L I ++GR G+ I I Q +GAQI +P V + G+ S+ LA Q
Sbjct: 256 HELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLA-Q 314
Query: 347 YLM 349
YL+
Sbjct: 315 YLI 317
Score = 32.0 bits (71), Expect = 2.9
Identities = 13/40 (32%), Positives = 25/40 (62%)
Query: 133 VTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSN 172
+T+++ + E +IGK G ++KK+ EE+G I+ + N
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN 53
>gi|42734375 ankyrin repeat and sterile alpha motif domain
containing 3 [Homo sapiens]
Length = 656
Score = 66.6 bits (161), Expect = 1e-10
Identities = 31/62 (50%), Positives = 44/62 (70%)
Query: 877 DLPELFSKLGLGKYTDVFQQQEIDLQTFLTLTDQDLKELGITTFGARRKMLLAISELNKN 936
DL L ++G KY VF++Q++DL+ FLTLT+ DLKE+GIT FG +RKM AI+ + +
Sbjct: 429 DLAALLEQIGCLKYLQVFEEQDVDLRIFLTLTESDLKEIGITLFGPKRKMTSAIARWHSS 488
Query: 937 RR 938
R
Sbjct: 489 AR 490
>gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens]
Length = 335
Score = 64.7 bits (156), Expect = 4e-10
Identities = 78/303 (25%), Positives = 132/303 (43%), Gaps = 34/303 (11%)
Query: 70 GRSGEDFFQKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLD-- 127
G+ GE +K+ EE+ +I I + + I ++G + +A MI+ L+
Sbjct: 30 GKKGESV-KKMREESGARI------NISEGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82
Query: 128 --------TKSNR--VTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSNRNNQA 177
T ++R VTL++ V ++ +IGKGG IK++ E TG + N
Sbjct: 83 ISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNST 142
Query: 178 EKSNQVSIAGQPAGVESARVRIRELLPLVLMFELPIAGILQPV-PDPNS-PSIQHISQTY 235
E++ ++IAG P + +I ++ L + + P G+ P P P+S P I Q Y
Sbjct: 143 ERA--ITIAGIPQSIIECVKQICVVM-LETLSQSPPKGVTIPYRPKPSSSPVIFAGGQAY 199
Query: 236 NISVSFK---------QRSRMYGATVIVRGSQNNTSAVKEGTAMLLEHLAGSLASAIPVS 286
I + + M + + S ++ + + + AG ASA S
Sbjct: 200 TIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTS 259
Query: 287 TQLDIAAQHHLFMMGRNGSNIKHIMQRTGAQIHFPDPSNPQKKSTVYLQGTIESVCLARQ 346
+L I ++GR G+ I I Q +GAQI +P V + G+ S+ LA Q
Sbjct: 260 HELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLA-Q 318
Query: 347 YLM 349
YL+
Sbjct: 319 YLI 321
Score = 32.0 bits (71), Expect = 2.9
Identities = 13/40 (32%), Positives = 25/40 (62%)
Query: 133 VTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSN 172
+T+++ + E +IGK G ++KK+ EE+G I+ + N
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN 53
>gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens]
Length = 318
Score = 64.3 bits (155), Expect = 5e-10
Identities = 80/294 (27%), Positives = 126/294 (42%), Gaps = 33/294 (11%)
Query: 70 GRSGEDFFQKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLD-- 127
G+ GE +K+ EE+ +I I + + I ++G + +A MI+ L+
Sbjct: 30 GKKGESV-KKMREESGARI------NISEGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82
Query: 128 --------TKSNR--VTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSNRNNQA 177
T ++R VTL++ V ++ +IGKGG IK++ E TG + N
Sbjct: 83 ISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNST 142
Query: 178 EKSNQVSIAGQPAGVESARVRIRELLPLVLMFELPIAGILQPV-PDPNS-PSIQHISQTY 235
E++ ++IAG P + +I V+M E P G+ P P P+S P I Q Y
Sbjct: 143 ERA--ITIAGIPQSIIECVKQI-----CVVMLESPPKGVTIPYRPKPSSSPVIFAGGQAY 195
Query: 236 NISVSFKQRSRMYGATVIVRGSQNNTSAVKEGTAMLLEHLAGSLASAIPVSTQLDIAAQH 295
I + + Q++ T AG ASA S +L I
Sbjct: 196 TIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFS----AGLDASAQTTSHELTIPNDL 251
Query: 296 HLFMMGRNGSNIKHIMQRTGAQIHFPDPSNPQKKSTVYLQGTIESVCLARQYLM 349
++GR G+ I I Q +GAQI +P V + G+ S+ LA QYL+
Sbjct: 252 IGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLA-QYLI 304
Score = 32.0 bits (71), Expect = 2.9
Identities = 13/40 (32%), Positives = 25/40 (62%)
Query: 133 VTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSN 172
+T+++ + E +IGK G ++KK+ EE+G I+ + N
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN 53
>gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens]
Length = 362
Score = 57.0 bits (136), Expect = 8e-08
Identities = 82/334 (24%), Positives = 134/334 (40%), Gaps = 69/334 (20%)
Query: 70 GRSGEDFFQKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLD-- 127
G+ GE +K+ EE+ +I I + + I ++G + +A MI+ L+
Sbjct: 30 GKKGESV-KKMREESGARI------NISEGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82
Query: 128 --------TKSNR--VTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSNRNNQA 177
T ++R VTL++ V ++ +IGKGG IK++ E TG + N
Sbjct: 83 ISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNST 142
Query: 178 EKSNQVSIAGQPAGVESARVRIRELLPLVLMFELPIAGILQPV-PDPNSPSI-----QHI 231
E++ ++IAG P + +I V+M E P G+ P P P+S + Q
Sbjct: 143 ERA--ITIAGIPQSIIECVKQI-----CVVMLESPPKGVTIPYRPKPSSSPVIFAGGQDR 195
Query: 232 SQTYNISVSFKQRSRMYGATVIVRG----------------------------------S 257
T + S SF + + G +
Sbjct: 196 YSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMT 255
Query: 258 QNNT--SAVKEGTAMLLEHLAGSLASAIPVSTQLDIAAQHHLFMMGRNGSNIKHIMQRTG 315
NT S ++ + + + AG ASA S +L I ++GR G+ I I Q +G
Sbjct: 256 HGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSG 315
Query: 316 AQIHFPDPSNPQKKSTVYLQGTIESVCLARQYLM 349
AQI +P V + G+ S+ LA QYL+
Sbjct: 316 AQIKIANPVEGSTDRQVTITGSAASISLA-QYLI 348
Score = 32.0 bits (71), Expect = 2.9
Identities = 13/40 (32%), Positives = 25/40 (62%)
Query: 133 VTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSN 172
+T+++ + E +IGK G ++KK+ EE+G I+ + N
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN 53
>gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens]
Length = 371
Score = 56.6 bits (135), Expect = 1e-07
Identities = 78/311 (25%), Positives = 131/311 (42%), Gaps = 46/311 (14%)
Query: 70 GRSGEDFFQKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIM-----S 124
G+ GE +K+ EE+ +I I + + + ++G + + +A MI
Sbjct: 62 GKKGETV-KKMREESGARI------NISEGNCPERIVTITGPTDAIFKAFAMIAYKFEED 114
Query: 125 VLDTKSNR-------VTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSNRNNQA 177
++++ SN VTL++ V ++ +IGKGG+ IK++ E TG + N
Sbjct: 115 IINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNST 174
Query: 178 EKSNQVSIAGQPAGVESARVRIRELLPLVLMFELPIAGILQPV-PDP-NSPSIQHISQTY 235
E++ V+I+G P + +I V+M E P G P P P ++P I Q Y
Sbjct: 175 ERA--VTISGTPDAIIQCVKQI-----CVVMLESPPKGATIPYRPKPASTPVIFAGGQAY 227
Query: 236 NISVSF---------KQRSRMYGATVIVRGSQNNTSAVKE-------GTAMLLEHLAGSL 279
I + K T Q N + E A L + L
Sbjct: 228 TIQGQYAIPHPDQLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGL 287
Query: 280 ASAIPVST-QLDIAAQHHLFMMGRNGSNIKHIMQRTGAQIHFPDPSNPQKKSTVYLQGTI 338
++ P ST +L I ++GR G+ I I Q +GAQI + + + + + GT
Sbjct: 288 DASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTP 347
Query: 339 ESVCLARQYLM 349
++ LA QYL+
Sbjct: 348 ANISLA-QYLI 357
Score = 31.6 bits (70), Expect = 3.8
Identities = 13/40 (32%), Positives = 24/40 (60%)
Query: 133 VTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSN 172
+T+++ + E +IGK G +KK+ EE+G I+ + N
Sbjct: 46 LTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGN 85
>gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens]
Length = 345
Score = 55.8 bits (133), Expect = 2e-07
Identities = 68/294 (23%), Positives = 127/294 (43%), Gaps = 38/294 (12%)
Query: 70 GRSGEDFFQKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIM-----S 124
G+ GE +K+ EE+ +I I + + + ++G + + +A MI
Sbjct: 62 GKKGETV-KKMREESGARI------NISEGNCPERIVTITGPTDAIFKAFAMIAYKFEED 114
Query: 125 VLDTKSNR-------VTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSNRNNQA 177
++++ SN VTL++ V ++ +IGKGG+ IK++ E TG + N
Sbjct: 115 IINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNST 174
Query: 178 EKSNQVSIAGQPAGVESARVRIRELLPLVLMFELPIAGILQPVPDPNSPSIQHISQTYNI 237
E++ V+I+G P + +I V+M E +P P+ + ++
Sbjct: 175 ERA--VTISGTPDAIIQCVKQI-----CVVMLEAYTIQGQYAIPHPDLTKLHQLAMQQTP 227
Query: 238 SVSFKQRSRMY-GATVIVRGSQNNTSAVKEGTAMLLEHLAGSLASAIPVST-QLDIAAQH 295
Q + + G + + S+ A L + L ++ P ST +L I
Sbjct: 228 FPPLGQTNPAFPGEKLPLHSSEE---------AQNLMGQSSGLDASPPASTHELTIPNDL 278
Query: 296 HLFMMGRNGSNIKHIMQRTGAQIHFPDPSNPQKKSTVYLQGTIESVCLARQYLM 349
++GR G+ I I Q +GAQI + + + + + GT ++ LA QYL+
Sbjct: 279 IGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLA-QYLI 331
Score = 31.6 bits (70), Expect = 3.8
Identities = 13/40 (32%), Positives = 24/40 (60%)
Query: 133 VTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSN 172
+T+++ + E +IGK G +KK+ EE+G I+ + N
Sbjct: 46 LTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGN 85
>gi|222352151 poly(rC) binding protein 1 [Homo sapiens]
Length = 356
Score = 54.3 bits (129), Expect = 5e-07
Identities = 77/325 (23%), Positives = 133/325 (40%), Gaps = 56/325 (17%)
Query: 70 GRSGEDFFQKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLDTK 129
G+ GE ++I EE+ +I I + + I ++G + +A MI+ L+
Sbjct: 30 GKKGESV-KRIREESGARI------NISEGNCPERIITLTGPTNAIFKAFAMIIDKLEED 82
Query: 130 SNR------------VTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSNRNNQA 177
N VTL++ V T+ +IGKGG IK++ E TG + N
Sbjct: 83 INSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNST 142
Query: 178 EKSNQVSIAGQPAGVESARVRIRELLPLVLMFELPIAGIL----QPVP-----------D 222
E++ ++IAG P V +I L+ L + + P ++ QP+P D
Sbjct: 143 ERA--ITIAGVPQSVTECVKQIC-LVMLETLSQSPQGRVMTIPYQPMPASSPVICAGGQD 199
Query: 223 PNSPSIQHISQTYNISVSFKQRSRMYGATVI----------VRGSQNNTSAVKEGTAML- 271
S + + T+++ + G I V Q++ + + GT
Sbjct: 200 RCSDAAGYPHATHDLEGPPLDAYSIQGQHTISPLDLAKLNQVARQQSHFAMMHGGTGFAG 259
Query: 272 -------LEHLAGSLASAIPVSTQLDIAAQHHLFMMGRNGSNIKHIMQRTGAQIHFPDPS 324
++ SL ++ + +L I ++GR G+NI I Q +GAQI +P
Sbjct: 260 IDSSSPEVKGYWASLDASTQTTHELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPV 319
Query: 325 NPQKKSTVYLQGTIESVCLARQYLM 349
V + G+ S+ LA QYL+
Sbjct: 320 EGSSGRQVTITGSAASISLA-QYLI 343
Score = 31.6 bits (70), Expect = 3.8
Identities = 12/40 (30%), Positives = 25/40 (62%)
Query: 133 VTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSN 172
+T+++ + E +IGK G ++K++ EE+G I+ + N
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGN 53
>gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens]
Length = 366
Score = 53.5 bits (127), Expect = 9e-07
Identities = 80/334 (23%), Positives = 135/334 (40%), Gaps = 65/334 (19%)
Query: 70 GRSGEDFFQKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLD-- 127
G+ GE +K+ EE+ +I I + + I ++G + +A MI+ L+
Sbjct: 30 GKKGESV-KKMREESGARI------NISEGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82
Query: 128 --------TKSNR--VTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSNRNNQA 177
T ++R VTL++ V ++ +IGKGG IK++ E TG + N
Sbjct: 83 ISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNST 142
Query: 178 EKSNQVSIAGQPAGVESARVRIRELLPLVLMFELPIAGILQPV-PDPNSPSI-----QHI 231
E++ ++IAG P + +I ++ L + + P G+ P P P+S + Q
Sbjct: 143 ERA--ITIAGIPQSIIECVKQICVVM-LETLSQSPPKGVTIPYRPKPSSSPVIFAGGQDR 199
Query: 232 SQTYNISVSFKQRSRMYGATVIVRG----------------------------------S 257
T + S SF + + G +
Sbjct: 200 YSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMT 259
Query: 258 QNNT--SAVKEGTAMLLEHLAGSLASAIPVSTQLDIAAQHHLFMMGRNGSNIKHIMQRTG 315
NT S ++ + + + AG ASA S +L I ++GR G+ I I Q +G
Sbjct: 260 HGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSG 319
Query: 316 AQIHFPDPSNPQKKSTVYLQGTIESVCLARQYLM 349
AQI +P V + G+ S+ LA QYL+
Sbjct: 320 AQIKIANPVEGSTDRQVTITGSAASISLA-QYLI 352
Score = 32.0 bits (71), Expect = 2.9
Identities = 13/40 (32%), Positives = 25/40 (62%)
Query: 133 VTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSN 172
+T+++ + E +IGK G ++KK+ EE+G I+ + N
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN 53
>gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens]
Length = 361
Score = 53.1 bits (126), Expect = 1e-06
Identities = 82/333 (24%), Positives = 131/333 (39%), Gaps = 68/333 (20%)
Query: 70 GRSGEDFFQKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLD-- 127
G+ GE +K+ EE+ +I I + + I ++G + +A MI+ L+
Sbjct: 30 GKKGESV-KKMREESGARI------NISEGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82
Query: 128 --------TKSNR--VTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSNRNNQA 177
T ++R VTL++ V ++ +IGKGG IK++ E TG + N
Sbjct: 83 ISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNST 142
Query: 178 EKSNQVSIAGQPAGVESARVRIRELLPLVLMFELPIAGILQPV-PDPNSPSI-----QHI 231
E++ ++IAG P + +I V+M E P G+ P P P+S + Q
Sbjct: 143 ERA--ITIAGIPQSIIECVKQI-----CVVMLESPPKGVTIPYRPKPSSSPVIFAGGQDR 195
Query: 232 SQTYNISVSFKQRSRMYGATVIVRG------SQNNTSAVKEGTAMLLEHLA--------- 276
T + S SF + + G + A+ + L LA
Sbjct: 196 YSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMT 255
Query: 277 --------------------GSLASAIPVSTQLDIAAQHHLFMMGRNGSNIKHIMQRTGA 316
G ASA S +L I ++GR G+ I I Q +GA
Sbjct: 256 HGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGA 315
Query: 317 QIHFPDPSNPQKKSTVYLQGTIESVCLARQYLM 349
QI +P V + G+ S+ LA QYL+
Sbjct: 316 QIKIANPVEGSTDRQVTITGSAASISLA-QYLI 347
Score = 32.0 bits (71), Expect = 2.9
Identities = 13/40 (32%), Positives = 25/40 (62%)
Query: 133 VTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSN 172
+T+++ + E +IGK G ++KK+ EE+G I+ + N
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN 53
>gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens]
Length = 403
Score = 52.8 bits (125), Expect = 2e-06
Identities = 55/224 (24%), Positives = 98/224 (43%), Gaps = 20/224 (8%)
Query: 133 VTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSNRNNQAEKSNQVSIAGQPAGV 192
VTL++ + ++ +IGK G IK++ E TG + N E++ V+++G P
Sbjct: 102 VTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERA--VTVSGVP--- 156
Query: 193 ESARVRIRELLPLVLMFELPIAGILQPVPDPNSPSIQHISQTYNISVSFKQRSRMYGATV 252
++ + +R++ ++L E P G P S +S SV YGA
Sbjct: 157 DAIILCVRQICAVIL--ESPPKGATIPYHPSLSLGTVLLSANQGFSV-----QGQYGAVT 209
Query: 253 ---IVRGSQNNTSAVKEGTAMLLEHL-AGSLASAIPVSTQLDIAAQHHLFMMGRNGSNIK 308
+ + Q ++ AV T ++ L G+ S+ D+ ++GR GS I
Sbjct: 210 PAEVTKLQQLSSHAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIG----CVIGRQGSKIS 265
Query: 309 HIMQRTGAQIHFPDPSNPQKKSTVYLQGTIESVCLARQYLMGCL 352
I Q +GA I + + + V + G+ S+ LA+ + CL
Sbjct: 266 EIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIALAQYLITACL 309
Score = 30.4 bits (67), Expect = 8.4
Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 3/59 (5%)
Query: 277 GSLASAIPVSTQLDIAAQHHLFMMGRNGSNIKHIMQRTGAQIHFPD---PSNPQKKSTV 332
G S PV+ +L I A ++G+ G+ IK I + TGAQ+ P++ ++ TV
Sbjct: 94 GGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTV 152
>gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens]
Length = 403
Score = 52.8 bits (125), Expect = 2e-06
Identities = 55/224 (24%), Positives = 98/224 (43%), Gaps = 20/224 (8%)
Query: 133 VTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSNRNNQAEKSNQVSIAGQPAGV 192
VTL++ + ++ +IGK G IK++ E TG + N E++ V+++G P
Sbjct: 102 VTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERA--VTVSGVP--- 156
Query: 193 ESARVRIRELLPLVLMFELPIAGILQPVPDPNSPSIQHISQTYNISVSFKQRSRMYGATV 252
++ + +R++ ++L E P G P S +S SV YGA
Sbjct: 157 DAIILCVRQICAVIL--ESPPKGATIPYHPSLSLGTVLLSANQGFSV-----QGQYGAVT 209
Query: 253 ---IVRGSQNNTSAVKEGTAMLLEHL-AGSLASAIPVSTQLDIAAQHHLFMMGRNGSNIK 308
+ + Q ++ AV T ++ L G+ S+ D+ ++GR GS I
Sbjct: 210 PAEVTKLQQLSSHAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIG----CVIGRQGSKIS 265
Query: 309 HIMQRTGAQIHFPDPSNPQKKSTVYLQGTIESVCLARQYLMGCL 352
I Q +GA I + + + V + G+ S+ LA+ + CL
Sbjct: 266 EIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIALAQYLITACL 309
Score = 30.4 bits (67), Expect = 8.4
Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 3/59 (5%)
Query: 277 GSLASAIPVSTQLDIAAQHHLFMMGRNGSNIKHIMQRTGAQIHFPD---PSNPQKKSTV 332
G S PV+ +L I A ++G+ G+ IK I + TGAQ+ P++ ++ TV
Sbjct: 94 GGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTV 152
>gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens]
Length = 365
Score = 49.7 bits (117), Expect = 1e-05
Identities = 80/333 (24%), Positives = 132/333 (39%), Gaps = 64/333 (19%)
Query: 70 GRSGEDFFQKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLD-- 127
G+ GE +K+ EE+ +I I + + I ++G + +A MI+ L+
Sbjct: 30 GKKGESV-KKMREESGARI------NISEGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82
Query: 128 --------TKSNR--VTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSNRNNQA 177
T ++R VTL++ V ++ +IGKGG IK++ E TG + N
Sbjct: 83 ISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNST 142
Query: 178 EKSNQVSIAGQPAGVESARVRIRELLPLVLMFELPIAGILQPV-PDPNSPSI-----QHI 231
E++ ++IAG P + +I ++ L + + P G+ P P P+S + Q
Sbjct: 143 ERA--ITIAGIPQSIIECVKQICVVM-LETLSQSPPKGVTIPYRPKPSSSPVIFAGGQDR 199
Query: 232 SQTYNISVSFKQRSRMYGATVIVRG------SQNNTSAVKEGTAMLLEHLA--------- 276
T + S SF + + G + A+ + L LA
Sbjct: 200 YSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMT 259
Query: 277 --------------------GSLASAIPVSTQLDIAAQHHLFMMGRNGSNIKHIMQRTGA 316
G ASA S +L I ++GR G+ I I Q +GA
Sbjct: 260 HGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGA 319
Query: 317 QIHFPDPSNPQKKSTVYLQGTIESVCLARQYLM 349
QI +P V + G+ S+ LA QYL+
Sbjct: 320 QIKIANPVEGSTDRQVTITGSAASISLA-QYLI 351
Score = 32.0 bits (71), Expect = 2.9
Identities = 13/40 (32%), Positives = 25/40 (62%)
Query: 133 VTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSN 172
+T+++ + E +IGK G ++KK+ EE+G I+ + N
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN 53
>gi|161019170 mucin 5AC [Homo sapiens]
Length = 6207
Score = 47.4 bits (111), Expect = 7e-05
Identities = 79/316 (25%), Positives = 123/316 (38%), Gaps = 33/316 (10%)
Query: 419 SSGVTIATSPSPASCPAGLACPSLDILASAGLGLTGLGLLGPTTLSLNTSTTPNSLLNAL 478
SS T +SP A+ L + A++ + L G T L+ +TTP + +
Sbjct: 3145 SSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSL-GTTWTRLSQTTTPTATM--- 3200
Query: 479 NSSVSPLQSPSSGTPSPTLWAPPLANTSSATGFSAIPHLMIPSTAQATLTNILLSGVPTY 538
S+ +P S TP + L T++ TG A + PS+ T + T
Sbjct: 3201 -STATP-----SSTPETVHTSTVLTTTATTTG--ATGSVATPSSTPGTAHTTKVLTTTTT 3252
Query: 539 GHTA-PSPPPGLT---PVDVHINSM-QTEGKKIS-AALNGHAQSPDIKYGAISTSSLGEK 592
G TA PS PG PV + + T G ++ +++ G +P + +T + G
Sbjct: 3253 GFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSM 3312
Query: 593 VLSANHGDPSIQTSGSEQTSPKSSPTEGCNDAFVEVGMP---RSPSHSGNAGDLKQMMCP 649
++ S QTSG+ T P + T + + P R+ S +G L
Sbjct: 3313 ATPSS----STQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLG----T 3364
Query: 650 SKVSCAKRQTVELLQGTKNSHLHSTDRLLS-DPELSATESPLA-DKKAPGSERAAER--A 705
+ ++ T T + HST L S P TESP + PG RA R A
Sbjct: 3365 THITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTA 3424
Query: 706 AAAQQNSERAHLAPRS 721
A + + L P S
Sbjct: 3425 TATPSKTRTSTLLPSS 3440
Score = 45.1 bits (105), Expect = 3e-04
Identities = 50/199 (25%), Positives = 78/199 (39%), Gaps = 11/199 (5%)
Query: 419 SSGVTIATSPSPASCPAGLACPSLDILASAGLGLTGLGLLGPTTLSLNTSTTPNSLLNAL 478
S+G T S +P + L PS + G T T +T +
Sbjct: 4906 STGSTATPSSTPGTTWI-LTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVT 4964
Query: 479 NSSVSPLQSPSSGTPSPTLWAPPLANTSSATGFSAIPHLMIPSTAQATLTNILLSGVPTY 538
+S +P SP + T P L + A T +AT F+AIP S+ T T + + PT
Sbjct: 4965 SSKATPSSSPGTATALPALRST--ATTPTATSFTAIP----SSSLGTTWTRLSQTTTPT- 5017
Query: 539 GHTAPSPPPGLTPVDVHINSMQTEGKKISAALNGHAQSPDIKYGAISTSSLGEKVLSANH 598
T + P TP VH +++ T + A G +P G T+ + +
Sbjct: 5018 -ATMSTATPSSTPETVHTSTVLTATATTTGA-TGSVATPSSTPGTAHTTKVPTTTTTGFT 5075
Query: 599 GDPSIQTSGSEQTSPKSSP 617
PS + G+ T P ++P
Sbjct: 5076 ATPS-SSPGTALTPPTTTP 5093
Score = 44.7 bits (104), Expect = 4e-04
Identities = 50/196 (25%), Positives = 77/196 (39%), Gaps = 11/196 (5%)
Query: 418 ESSGVTIATSPSPASCPAGLACPSLDILASAGLGLTGLGLLGPTTLSLNTSTTPNSLLNA 477
ES+G T S +P + L PS + G T T +T +
Sbjct: 3085 ESTGSTATPSSTPGTTWI-LTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTV 3143
Query: 478 LNSSVSPLQSPSSGTPSPTLWAPPLANTSSATGFSAIPHLMIPSTAQATLTNILLSGVPT 537
+S +P SP + T P L + A T +AT F+AIP S+ T T + + PT
Sbjct: 3144 TSSKATPFSSPGTATALPALRST--ATTPTATSFTAIP----SSSLGTTWTRLSQTTTPT 3197
Query: 538 YGHTAPSPPPGLTPVDVHINSMQTEGKKISAALNGHAQSPDIKYGAISTSSLGEKVLSAN 597
T + P TP VH +++ T + A G +P G T+ + +
Sbjct: 3198 --ATMSTATPSSTPETVHTSTVLTTTATTTGA-TGSVATPSSTPGTAHTTKVLTTTTTGF 3254
Query: 598 HGDPSIQTSGSEQTSP 613
PS + G+ +T P
Sbjct: 3255 TATPS-SSPGTARTLP 3269
Score = 43.5 bits (101), Expect = 0.001
Identities = 52/200 (26%), Positives = 77/200 (38%), Gaps = 22/200 (11%)
Query: 418 ESSGVTIATSPSPASCPAGLACPSLDILASAGLGLTGLGLLGPTTLSLNTSTTPNSLLNA 477
ES+G T S +P + L PS + G T T +T +
Sbjct: 4232 ESTGSTATPSSTPGTTWI-LTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTV 4290
Query: 478 LNSSVSPLQSPSSGTPSPTLWAPPLANTSSATGFSAIPHLMIPSTAQATLTNILLSGVPT 537
+S +P SP + T P L + A T +AT F+AIP S+ T T + + PT
Sbjct: 4291 TSSKATPFSSPGTATALPALRST--ATTPTATSFTAIP----SSSLGTTWTRLSQTTTPT 4344
Query: 538 YGHTAPSPPPGLTPVDVHINSMQTEGKKISAALNGHAQSPDIKYGAISTSSLGEKVLSAN 597
T + P TP H +++ T + A G +P G T+ +
Sbjct: 4345 --ATMSTATPSSTPETAHTSTVLTTTATTTRA-TGSVATPSSTPGTAHTTKV-------- 4393
Query: 598 HGDPSIQTSGSEQTSPKSSP 617
P+ T+G T P SSP
Sbjct: 4394 ---PTTTTTGFTVT-PSSSP 4409
Score = 41.2 bits (95), Expect = 0.005
Identities = 55/205 (26%), Positives = 81/205 (39%), Gaps = 35/205 (17%)
Query: 423 TIATSPS--PASCPAG---LACPSLDILASAGLGLTGLG-----LLGPTTLSLNTSTTPN 472
T AT P+ P+S P L PS + G T G + +T+TTP
Sbjct: 3728 TAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPT 3787
Query: 473 SLLNALNSSVSPLQSPSSGTPSPTLWAPPLANTSSATGFSAIPHLMIPSTAQATLTNILL 532
++S +P SP + T P L + A T +AT +AIP S+ T +
Sbjct: 3788 ----VISSRATPSSSPGTATALPALRS--TATTPTATSVTAIP----SSSLGTAWTRLSQ 3837
Query: 533 SGVPTYGHTAPSPPPGLTPVDVHINSMQTEGKKISAALNGHAQSPDIKYGAISTSSLGEK 592
+ PT T + P TP VH +++ T + A G +P G T+ +
Sbjct: 3838 TTTPT--ATMSTATPSSTPETVHTSTVLTTTTTTTRA-TGSVATPSSTPGTAHTTKV--- 3891
Query: 593 VLSANHGDPSIQTSGSEQTSPKSSP 617
P+ T+G T P SSP
Sbjct: 3892 --------PTTTTTGFTAT-PSSSP 3907
Score = 34.7 bits (78), Expect = 0.45
Identities = 40/154 (25%), Positives = 61/154 (39%), Gaps = 25/154 (16%)
Query: 408 YEARK--CLLGLESSGVTIATSPSPASCPAGLACPSLDILASAGLGLTGL--------GL 457
YE R C G S +++ +P+S P + A+ TG G
Sbjct: 3542 YEIRVFCCNYGHCPSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGT 3601
Query: 458 LGPTTLSLNTSTTPNSLLNALNSSVSPLQSPSSGTPSPTLWAPPLANTSSATGFSAIPHL 517
P + +T+TTP A +S + SP + T P L + A S+AT F+ IP
Sbjct: 3602 APPPKVLTSTATTP----TATSSKATSSSSPRTATTLPVLTS--TATKSTATSFTPIPSF 3655
Query: 518 MI---------PSTAQATLTNILLSGVPTYGHTA 542
+ +T AT++ I S P HT+
Sbjct: 3656 TLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTS 3689
Score = 33.5 bits (75), Expect = 1.00
Identities = 53/200 (26%), Positives = 80/200 (40%), Gaps = 22/200 (11%)
Query: 420 SGVTIATSPSPASCPAGLACPSLDILASAGLGLTGLGLLGPTTLSLNTSTTPNSLLNALN 479
S T +++P A P L P+ A++ + TTL + TST S
Sbjct: 4738 STATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTA---- 4793
Query: 480 SSVSPLQSPSSGTPS--PTLWAPPLANTSSATGFSAIPHLMIPSTAQATLTNILLSGVPT 537
+SV+P+ S + GT P P+A T S S+ P ST LT + T
Sbjct: 4794 TSVTPIPSSTLGTTGTLPEQTTTPVA-TMSTIHPSSTPETTHTST---VLTTKATTTRAT 4849
Query: 538 YGHTAPSPPPGLTPVDVHINSMQTEGKKISAALNGHAQSPDIKYGAISTSSLGEKVLSAN 597
+ PS PG T + + + T + A G +P G +T L E +A
Sbjct: 4850 SSTSTPSSTPGTTWILTELTTAAT-----TTAATGPTATPSSTPG--TTWILTELTTTAT 4902
Query: 598 HGDPSIQTSGSEQTSPKSSP 617
+ ++GS T P S+P
Sbjct: 4903 ----TTASTGSTAT-PSSTP 4917
>gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
polymerase 2 [Homo sapiens]
Length = 1166
Score = 47.4 bits (111), Expect = 7e-05
Identities = 35/130 (26%), Positives = 64/130 (49%), Gaps = 11/130 (8%)
Query: 820 NGI-GPGSHSEFAAS-IGSPKRKQNKSTEHYLSSSNYMDCISSLTGSNGCNLNSSFKGSD 877
NG+ PG+ ++ +S SP S+ LS S +SS+ S+G SS + +
Sbjct: 813 NGVRSPGATADALSSGPSSPSSLSAASSLDNLSGS--FSELSSVVSSSGTEGASSLEKKE 870
Query: 878 LP-------ELFSKLGLGKYTDVFQQQEIDLQTFLTLTDQDLKELGITTFGARRKMLLAI 930
+P + LGL D+F++++I L + + ++LKE+GI +G R K++ +
Sbjct: 871 VPGVDFSITQFVRNLGLEHLMDIFEREQITLDVLVEMGHKELKEIGINAYGHRHKLIKGV 930
Query: 931 SELNKNRRKL 940
L ++ L
Sbjct: 931 ERLISGQQGL 940
>gi|197276670 spermatogenesis and centriole associated 1 isoform 2
[Homo sapiens]
Length = 441
Score = 45.8 bits (107), Expect = 2e-04
Identities = 72/321 (22%), Positives = 119/321 (37%), Gaps = 48/321 (14%)
Query: 417 LESSGVTIATSPSPASCPAGLACPSLDILASAGLGLTGLGLLGPTTLSLNTSTTPNSLLN 476
L T +SP + + +A P LAS+ LGL G L P++L S
Sbjct: 125 LSGPAPTSQSSPLTSFLTSPIAGPLTGTLASS-LGLPSTGTLTPSSLVAGPVAMSQS--- 180
Query: 477 ALNSSVSPLQSPSSGTPSPTLWAPPLANTSSATGFSA------IPHLMIPSTAQATLTNI 530
SPL +P GT + +L +P L++T++ G S + +L++P + L
Sbjct: 181 ------SPLIAPVMGTVAVSLSSPLLSSTATPPGVSQNLLANPMSNLVLPEAPRLRLAEP 234
Query: 531 LLSGVPTYGHTAPSPPPGLTPVDVHINSMQTEGKKISAALNGHAQSPDIKYGAISTSSLG 590
L G T P P + P + TE + + Q P+ A + + L
Sbjct: 235 LRGGP-----TGPQSPACVVPTATTKVPLSTEPPQST-------QDPEPLSMAFAGAPLQ 282
Query: 591 EKVLSANHGDPSIQTSGSEQTSPKSSPTEGCNDAFVEVGMPRSPSHSGNAGDLKQ--MMC 648
G P+ +T+ S TS + + V +P SP+ S L +
Sbjct: 283 TSTPIGAMGTPAPKTAFSFNTSDTQAQPSAAQEQVVPASVPTSPTTSPTVTVLASAPALA 342
Query: 649 PS-KVSCAKRQTVELLQGTKN--SHLHST------------DRLLSDPELSATESPLADK 693
P S T + QG + S +H++ S P S++ + + D
Sbjct: 343 PQVATSYTPSSTTHIAQGAPHPPSRMHNSPTQNLPVPHCPPHNAHSPPRTSSSPASVNDS 402
Query: 694 KAPGSERAAERAAAAQQNSER 714
+ P R E + + ER
Sbjct: 403 RGP---RTTEPSTKSMMEVER 420
>gi|197276668 spermatogenesis and centriole associated 1 isoform 1
[Homo sapiens]
Length = 591
Score = 45.8 bits (107), Expect = 2e-04
Identities = 72/321 (22%), Positives = 119/321 (37%), Gaps = 48/321 (14%)
Query: 417 LESSGVTIATSPSPASCPAGLACPSLDILASAGLGLTGLGLLGPTTLSLNTSTTPNSLLN 476
L T +SP + + +A P LAS+ LGL G L P++L S
Sbjct: 125 LSGPAPTSQSSPLTSFLTSPIAGPLTGTLASS-LGLPSTGTLTPSSLVAGPVAMSQS--- 180
Query: 477 ALNSSVSPLQSPSSGTPSPTLWAPPLANTSSATGFSA------IPHLMIPSTAQATLTNI 530
SPL +P GT + +L +P L++T++ G S + +L++P + L
Sbjct: 181 ------SPLIAPVMGTVAVSLSSPLLSSTATPPGVSQNLLANPMSNLVLPEAPRLRLAEP 234
Query: 531 LLSGVPTYGHTAPSPPPGLTPVDVHINSMQTEGKKISAALNGHAQSPDIKYGAISTSSLG 590
L G T P P + P + TE + + Q P+ A + + L
Sbjct: 235 LRGGP-----TGPQSPACVVPTATTKVPLSTEPPQST-------QDPEPLSMAFAGAPLQ 282
Query: 591 EKVLSANHGDPSIQTSGSEQTSPKSSPTEGCNDAFVEVGMPRSPSHSGNAGDLKQ--MMC 648
G P+ +T+ S TS + + V +P SP+ S L +
Sbjct: 283 TSTPIGAMGTPAPKTAFSFNTSDTQAQPSAAQEQVVPASVPTSPTTSPTVTVLASAPALA 342
Query: 649 PS-KVSCAKRQTVELLQGTKN--SHLHST------------DRLLSDPELSATESPLADK 693
P S T + QG + S +H++ S P S++ + + D
Sbjct: 343 PQVATSYTPSSTTHIAQGAPHPPSRMHNSPTQNLPVPHCPPHNAHSPPRTSSSPASVNDS 402
Query: 694 KAPGSERAAERAAAAQQNSER 714
+ P R E + + ER
Sbjct: 403 RGP---RTTEPSTKSMMEVER 420
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 45.1 bits (105), Expect = 3e-04
Identities = 50/157 (31%), Positives = 69/157 (43%), Gaps = 25/157 (15%)
Query: 415 LGLESSGVTIATSPSPASCPAGLACPSLDILASAGLGLTGLGL-LGPTTL-SLNTSTTP- 471
L + +SG + TS +P P A P LA +G + L LG T SL++S TP
Sbjct: 1463 LTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPG 1522
Query: 472 --------NSLLNALNSSVSPLQSP----SSGTPSPTLWAPPLANTSSATGFSAIPHLMI 519
+S + LNS+V+P SP +S SP AP A ++ L+
Sbjct: 1523 HPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQAS--------LLA 1574
Query: 520 P--STAQATLTNILLSGVPTYGHTAPSPPPGLTPVDV 554
P S +QA T + P APSP P L P+ V
Sbjct: 1575 PASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPV 1611
Score = 34.7 bits (78), Expect = 0.45
Identities = 80/315 (25%), Positives = 118/315 (37%), Gaps = 68/315 (21%)
Query: 419 SSGVTIATSPSPASCPAGLACPSLDILASAGLGLTGLGLLGPTTLSLNTSTTPNSLLNAL 478
SSG+ +P P P L P+ L +A + L+ P L L S +P +A
Sbjct: 1335 SSGLPAVLNPRPTLTPGRLPTPT---LGTARAPMPTPTLVRP-LLKLVHSPSPEVSASAP 1390
Query: 479 NSS----VSPLQSPSSGTPSPTLWAPPLANTSSATGFSAIPHLMIPSTAQATLTNILLSG 534
++ SPL PSS P P P+ N+S + ST L++ L
Sbjct: 1391 GAAPLTISSPLHVPSS-LPGPASSPMPIPNSSPLAS-------PVSSTVSVPLSSSLPIS 1442
Query: 535 VPTYGHTAPSPPPGLTPVDVHINSMQTEGKKISAALNGHAQSPDIKYGAISTSSLGEKVL 594
VPT P P P+ + ISA L A P + S + V+
Sbjct: 1443 VPT-----TLPAPASAPLTI----------PISAPLTVSASGPAL---LTSVTPPLAPVV 1484
Query: 595 SANHGDPSIQTSGSEQTSPKSSPTEGCNDAFVEVGMPRSPSHSGNAGDLKQMMCPSKVSC 654
A G PS+ SG+ SP +S + +G+ +PS +S
Sbjct: 1485 PAAPGPPSLAPSGA---SPSASA--------LTLGLATAPS----------------LSS 1517
Query: 655 AKRQTVELLQGTKNSH---LHSTDRLLSDPEL---SATESPLADKKAPGSERAAERAAAA 708
++ LL +SH L+ST P L SA SP P +A+ A A+
Sbjct: 1518 SQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPAS 1577
Query: 709 QQNSERA-HLAPRSS 722
+ A LAP ++
Sbjct: 1578 SASQALATPLAPMAA 1592
Score = 31.6 bits (70), Expect = 3.8
Identities = 33/121 (27%), Positives = 51/121 (42%), Gaps = 21/121 (17%)
Query: 424 IATSPSPASCPAGLACPSLDILASAGLGLTGLGLLGPTTLSLNTSTTPNSLLNALNSSVS 483
+A SP+P P + PS T + ++ P S+TP + L +S S
Sbjct: 1598 LAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAP-------SSTPGTSL----ASAS 1646
Query: 484 PLQSPSSGTPSPTLWAPPLANTSSATGFSAIPHLMIPSTAQATLTNILLSGVPTYGHTAP 543
P+ P+PT P LA +S+ T A +PS A + + PT G ++P
Sbjct: 1647 PV-------PAPT---PVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSP 1696
Query: 544 S 544
S
Sbjct: 1697 S 1697
Score = 31.6 bits (70), Expect = 3.8
Identities = 39/157 (24%), Positives = 59/157 (37%), Gaps = 22/157 (14%)
Query: 480 SSVSPLQSPSSGTPSPTLWAPPLANTSSATGFSAIPHLMIPSTAQATLTNILLSGVPTYG 539
+S PLQ P + + L + T P ++ + A T+ + P G
Sbjct: 2659 ASDEPLQEPLEADRT----SEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPE-G 2713
Query: 540 HTAPSPPPGLTPVDVHINSM------QTEGKKISAALNGH----AQSPDI------KYGA 583
+ PP T DV I Q G K+ L G + ++ + GA
Sbjct: 2714 PSPARPPRRRTSADVEIRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGA 2773
Query: 584 ISTSSLGEKVLSANHGDPSIQT-SGSEQTSPKSSPTE 619
ST G SA+ G PS+++ SG E + P P E
Sbjct: 2774 ASTLVPGVSETSASPGSPSVRSMSGPESSPPIGGPCE 2810
>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
Length = 5765
Score = 44.7 bits (104), Expect = 4e-04
Identities = 50/196 (25%), Positives = 77/196 (39%), Gaps = 11/196 (5%)
Query: 418 ESSGVTIATSPSPASCPAGLACPSLDILASAGLGLTGLGLLGPTTLSLNTSTTPNSLLNA 477
ES+G T S +P + L PS + G T T +T +
Sbjct: 2450 ESTGSTATPSSTPGTTWI-LTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTV 2508
Query: 478 LNSSVSPLQSPSSGTPSPTLWAPPLANTSSATGFSAIPHLMIPSTAQATLTNILLSGVPT 537
+S +P SP + T P L + A T +AT F+AIP S+ T T + + PT
Sbjct: 2509 TSSKATPFSSPGTATALPALRST--ATTPTATSFTAIP----SSSLGTTWTRLSQTTTPT 2562
Query: 538 YGHTAPSPPPGLTPVDVHINSMQTEGKKISAALNGHAQSPDIKYGAISTSSLGEKVLSAN 597
T + P TP VH +++ T + A G +P G T+ + +
Sbjct: 2563 --ATMSTATPSSTPETVHTSTVLTTTATTTGA-TGSVATPSSTPGTAHTTKVLTTTTTGF 2619
Query: 598 HGDPSIQTSGSEQTSP 613
PS + G+ +T P
Sbjct: 2620 TATPS-SSPGTARTLP 2634
Score = 43.5 bits (101), Expect = 0.001
Identities = 52/200 (26%), Positives = 77/200 (38%), Gaps = 22/200 (11%)
Query: 418 ESSGVTIATSPSPASCPAGLACPSLDILASAGLGLTGLGLLGPTTLSLNTSTTPNSLLNA 477
ES+G T S +P + L PS + G T T +T +
Sbjct: 3707 ESTGSTATPSSTPGTTWI-LTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTV 3765
Query: 478 LNSSVSPLQSPSSGTPSPTLWAPPLANTSSATGFSAIPHLMIPSTAQATLTNILLSGVPT 537
+S +P SP + T P L + A T +AT F+AIP S+ T T + + PT
Sbjct: 3766 TSSKATPFSSPGTATALPALRST--ATTPTATSFTAIP----SSSLGTTWTRLSQTTTPT 3819
Query: 538 YGHTAPSPPPGLTPVDVHINSMQTEGKKISAALNGHAQSPDIKYGAISTSSLGEKVLSAN 597
T + P TP H +++ T + A G +P G T+ +
Sbjct: 3820 --ATMSTATPSSTPETAHTSTVLTTTATTTRA-TGSVATPSSTPGTAHTTKV-------- 3868
Query: 598 HGDPSIQTSGSEQTSPKSSP 617
P+ T+G T P SSP
Sbjct: 3869 ---PTTTTTGFTVT-PSSSP 3884
Score = 43.1 bits (100), Expect = 0.001
Identities = 52/199 (26%), Positives = 77/199 (38%), Gaps = 22/199 (11%)
Query: 419 SSGVTIATSPSPASCPAGLACPSLDILASAGLGLTGLGLLGPTTLSLNTSTTPNSLLNAL 478
S+G T S +P + L PS + G T T +T +
Sbjct: 4436 STGSTATPSSTPGTTWI-LTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVT 4494
Query: 479 NSSVSPLQSPSSGTPSPTLWAPPLANTSSATGFSAIPHLMIPSTAQATLTNILLSGVPTY 538
+S +P SP + T P L + A T +AT F+AIP S+ T T + + PT
Sbjct: 4495 SSKATPSSSPGTATALPALRST--ATTPTATSFTAIP----SSSLGTTWTRLSQTTTPT- 4547
Query: 539 GHTAPSPPPGLTPVDVHINSMQTEGKKISAALNGHAQSPDIKYGAISTSSLGEKVLSANH 598
T + P TP VH +++ T + A G +P G T+ +
Sbjct: 4548 -ATMSTATPSSTPETVHTSTVLTATATTTGA-TGSVATPSSTPGTAHTTKV--------- 4596
Query: 599 GDPSIQTSGSEQTSPKSSP 617
P+ T+G T P SSP
Sbjct: 4597 --PTTTTTGFTAT-PSSSP 4612
Score = 41.2 bits (95), Expect = 0.005
Identities = 55/205 (26%), Positives = 81/205 (39%), Gaps = 35/205 (17%)
Query: 423 TIATSPS--PASCPAG---LACPSLDILASAGLGLTGLG-----LLGPTTLSLNTSTTPN 472
T AT P+ P+S P L PS + G T G + +T+TTP
Sbjct: 3148 TAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPT 3207
Query: 473 SLLNALNSSVSPLQSPSSGTPSPTLWAPPLANTSSATGFSAIPHLMIPSTAQATLTNILL 532
++S +P SP + T P L + A T +AT +AIP S+ T +
Sbjct: 3208 ----VISSRATPSSSPGTATALPALRS--TATTPTATSVTAIP----SSSLGTAWTRLSQ 3257
Query: 533 SGVPTYGHTAPSPPPGLTPVDVHINSMQTEGKKISAALNGHAQSPDIKYGAISTSSLGEK 592
+ PT T + P TP VH +++ T + A G +P G T+ +
Sbjct: 3258 TTTPT--ATMSTATPSSTPETVHTSTVLTTTTTTTRA-TGSVATPSSTPGTAHTTKV--- 3311
Query: 593 VLSANHGDPSIQTSGSEQTSPKSSP 617
P+ T+G T P SSP
Sbjct: 3312 --------PTTTTTGFTAT-PSSSP 3327
Score = 37.0 bits (84), Expect = 0.090
Identities = 75/306 (24%), Positives = 108/306 (35%), Gaps = 56/306 (18%)
Query: 429 SPASCPAGLACPSLDILASAGLGLTGLGLLGPTTLS-----LNTSTTPNSLLNALNSSVS 483
+P+S P + +L + G T P T ++T+TTP + S+V+
Sbjct: 2598 TPSSTPG--TAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTR----GSTVT 2651
Query: 484 PLQSPSSGTPSPTLWAPPLANTSSATGFSAIPHLMIPSTAQA-TLTNILLSGVPTYGHTA 542
P P + T +PT+ T+ ATG A P ++ +LT + T T
Sbjct: 2652 PSSIPGT-THTPTVLTT--TTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTN 2708
Query: 543 PSPPPGLTPVDVHINSMQTEGKKISAALNGHAQSPDIKYGAISTSSLGEKVLSANHGDP- 601
PS PG TP I L A +P ++ SS L H P
Sbjct: 2709 PSSTPGTTP--------------IPPVLTTTATTPAATSSTVTPSS----ALGTTHTPPV 2750
Query: 602 --SIQTSGSEQTSPKSSPTEGCNDAFVEVGMPRSPSHSGNAGDLKQMMCPSKVSCAKRQT 659
+ T+ SP S T V + + SG G + ++ T
Sbjct: 2751 PNTTATTHGRSLSPSSPHT---------VRTAWTSATSGTLG-------TTHITEPSTGT 2794
Query: 660 VELLQGTKNSHLHSTDRLLS-DPELSATESPLA-DKKAPGSERAAER--AAAAQQNSERA 715
T + HST L S P TESP + PG RA R A A + +
Sbjct: 2795 SHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTATATPSKTRTS 2854
Query: 716 HLAPRS 721
L P S
Sbjct: 2855 TLLPSS 2860
Score = 36.6 bits (83), Expect = 0.12
Identities = 77/305 (25%), Positives = 110/305 (36%), Gaps = 54/305 (17%)
Query: 429 SPASCPAGLACPSLDILASAGLGLT-----GLGLLGPTTLSLNTSTTPNSLLNALNSSVS 483
+P+S P + + G T G L P +S T+TTP + S+V+
Sbjct: 2041 TPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWIS--TTTTPTTR----GSTVT 2094
Query: 484 PLQSPSSGTPSPTLWAPPLANTSS--ATGFSAIPHLMIPSTAQA-TLTNILLSGVPTYGH 540
P S P T A L T++ ATG A P ++ +LT + T
Sbjct: 2095 P-----SSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGST 2149
Query: 541 TAPSPPPGLTPVDVHINSMQTEGKKISAALNGHAQSPDIKYGAISTSSLGEKVLSANHGD 600
T PS PG TP+ + + T + A + +P G T + ++ HG
Sbjct: 2150 TNPSSTPGTTPIPPVLTTTAT-----TPAATSNTVTPSSALGTTHTPPV-PNTMATTHG- 2202
Query: 601 PSIQTSGSEQTSPKSSPTEGCNDAFVEVGMPRSPSHSGNAGDLKQMMCPSKVSCAKRQTV 660
++ P SSP V + + SG G + PS V T
Sbjct: 2203 ---------RSLPPSSPH--------TVRTAWTSATSGILG-TTHITEPSTV------TS 2238
Query: 661 ELLQGTKNSHLHSTDRLLS-DPELSATESPLA-DKKAPGSERAAER--AAAAQQNSERAH 716
L T + HST L S P TESP + PG A R A A + +
Sbjct: 2239 HTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTST 2298
Query: 717 LAPRS 721
L P S
Sbjct: 2299 LLPSS 2303
Score = 34.7 bits (78), Expect = 0.45
Identities = 50/206 (24%), Positives = 85/206 (41%), Gaps = 22/206 (10%)
Query: 419 SSGVTIATSPSPASCPAGLACPSLDILASAGLGLTGLGLLGPTTLSLNTSTTPNSLLNAL 478
SS T +SP A+ L + A++ + L G T L+ +TTP + +
Sbjct: 2510 SSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSL-GTTWTRLSQTTTPTATM--- 2565
Query: 479 NSSVSPLQSPSSGTPSPTLWAPPLANTSSATGFSAIPHLMIPSTAQATLTNILLSGVPTY 538
S+ +P S TP + L T++ TG A + PS+ T + T
Sbjct: 2566 -STATP-----SSTPETVHTSTVLTTTATTTG--ATGSVATPSSTPGTAHTTKVLTTTTT 2617
Query: 539 GHTA-PSPPPGLT---PVDVHINSM-QTEGKKIS-AALNGHAQSPDIKYGAISTSSLGEK 592
G TA PS PG PV + + T G ++ +++ G +P + +T + G
Sbjct: 2618 GFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSM 2677
Query: 593 VLSANHGDPSIQTSGSEQTSPKSSPT 618
++ S QTSG+ + ++ T
Sbjct: 2678 ATPSS----STQTSGTPPSLTTTATT 2699
Score = 34.7 bits (78), Expect = 0.45
Identities = 40/154 (25%), Positives = 61/154 (39%), Gaps = 25/154 (16%)
Query: 408 YEARK--CLLGLESSGVTIATSPSPASCPAGLACPSLDILASAGLGLTGL--------GL 457
YE R C G S +++ +P+S P + A+ TG G
Sbjct: 2962 YEIRVFCCNYGHCPSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGT 3021
Query: 458 LGPTTLSLNTSTTPNSLLNALNSSVSPLQSPSSGTPSPTLWAPPLANTSSATGFSAIPHL 517
P + +T+TTP A +S + SP + T P L + A S+AT F+ IP
Sbjct: 3022 APPPKVLTSTATTP----TATSSKATSSSSPRTATTLPVLTS--TATKSTATSFTPIPSF 3075
Query: 518 MI---------PSTAQATLTNILLSGVPTYGHTA 542
+ +T AT++ I S P HT+
Sbjct: 3076 TLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTS 3109
Score = 34.3 bits (77), Expect = 0.58
Identities = 79/307 (25%), Positives = 109/307 (35%), Gaps = 58/307 (18%)
Query: 429 SPASCPAGLACPSLDILASAGLGLT-----GLGLLGPTTLSLNTSTTPNSLLNALNSSVS 483
+P+S P + + G T G L P +S T+TTP + S+V+
Sbjct: 3298 TPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWIS--TTTTPTTR----GSTVT 3351
Query: 484 PLQSPSSGTPSPTLWAPPLANTSS--ATGFSAIPHLMIPSTAQA-TLTNILLSGVPTYGH 540
P S P T A L T++ ATG A P ++ +LT + T
Sbjct: 3352 P-----SSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGST 3406
Query: 541 TAPSPPPGLTPVDVHINSMQTEGKKISAALNGHAQSPDIKYGAISTSSLGEKVLSANHGD 600
T PS PG TP I L A +P ++ SS L H
Sbjct: 3407 TNPSSTPGTTP--------------IPPVLTTTATTPAATSSTVTPSS----ALGTTHTP 3448
Query: 601 PSIQTSGSE--QTSPKSSPTEGCNDAFVEVGMPRSPSHSGNAGDLKQMMCPSKVSCAKRQ 658
P T+ + ++ P SSP V + + SG G + PS V
Sbjct: 3449 PVPNTTATTHGRSLPPSSPH--------TVRTAWTSATSGILG-TTHITEPSTV------ 3493
Query: 659 TVELLQGTKNSHLHSTDRLLS-DPELSATESPLA-DKKAPGSERAAER--AAAAQQNSER 714
T T ++ HST L S P TESP + PG R R A A +
Sbjct: 3494 TSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRT 3553
Query: 715 AHLAPRS 721
+ L P S
Sbjct: 3554 STLLPSS 3560
Score = 33.5 bits (75), Expect = 1.00
Identities = 53/200 (26%), Positives = 80/200 (40%), Gaps = 22/200 (11%)
Query: 420 SGVTIATSPSPASCPAGLACPSLDILASAGLGLTGLGLLGPTTLSLNTSTTPNSLLNALN 479
S T +++P A P L P+ A++ + TTL + TST S
Sbjct: 4268 STATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTA---- 4323
Query: 480 SSVSPLQSPSSGTPS--PTLWAPPLANTSSATGFSAIPHLMIPSTAQATLTNILLSGVPT 537
+SV+P+ S + GT P P+A T S S+ P ST LT + T
Sbjct: 4324 TSVTPIPSSTLGTTGTLPEQTTTPVA-TMSTIHPSSTPETTHTST---VLTTKATTTRAT 4379
Query: 538 YGHTAPSPPPGLTPVDVHINSMQTEGKKISAALNGHAQSPDIKYGAISTSSLGEKVLSAN 597
+ PS PG T + + + T + A G +P G +T L E +A
Sbjct: 4380 SSTSTPSSTPGTTWILTELTTAAT-----TTAATGPTATPSSTPG--TTWILTELTTTAT 4432
Query: 598 HGDPSIQTSGSEQTSPKSSP 617
+ ++GS T P S+P
Sbjct: 4433 ----TTASTGSTAT-PSSTP 4447
Score = 32.3 bits (72), Expect = 2.2
Identities = 39/142 (27%), Positives = 57/142 (40%), Gaps = 16/142 (11%)
Query: 429 SPASCPAGLACPSLDILASAGLGLT-----GLGLLGPTTLSLNTSTTPNSLLNALN-SSV 482
+P+S P + + G T G L P +S T+TTP + + S+V
Sbjct: 4583 TPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWIS--TTTTPTTTTPTTSGSTV 4640
Query: 483 SPLQSPSSGTPSPTLWAPPLANTSS--ATGFSAIPHLMIPSTAQA-TLTNILLSGVPTYG 539
+P S P T A L T++ ATG A P ++ +LT + T
Sbjct: 4641 TP-----SSIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGS 4695
Query: 540 HTAPSPPPGLTPVDVHINSMQT 561
T PS PG TP+ + S T
Sbjct: 4696 TTNPSSTPGTTPITPVLTSTAT 4717
Score = 31.6 bits (70), Expect = 3.8
Identities = 51/242 (21%), Positives = 92/242 (38%), Gaps = 21/242 (8%)
Query: 423 TIATSPSPASCPAGLACPSLDILASAGLGLTGLGLLGPTTLSLNTSTTPNSLLNALNS-- 480
T ++ +P+S P P++ + + G + + S TS TP SL+ +
Sbjct: 3902 TSGSTVTPSSVPGTTHTPTVLTTTTTTVAT---GSMATPSSSTQTSGTPPSLITTATTIT 3958
Query: 481 SVSPLQSPSSGTPSPTLWAPPLANTSSATGFSAIPHLMIPSTAQATLTNILLSGVPTYGH 540
+ +PSS TP T P L T++AT +A + PS+A T P
Sbjct: 3959 ATGSTTNPSS-TPGTTPIPPVL--TTTATTPAATSSTVTPSSALGTTHT-----PPVPNT 4010
Query: 541 TAPSPPPGLTPVDVHINSMQTEGKKISAALNG--HAQSPDIKYGAISTSSLGEKVLSANH 598
TA + L+P H +++T ++ G H P ++ G + H
Sbjct: 4011 TATTHGRSLSPSSPH--TVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTG----TTQH 4064
Query: 599 GDPSIQTSGSEQTSPKSSPTEGCNDAFVEVGMPRSPSHSGNAGDLKQMMCPSKVSCAKRQ 658
P++ + + +S P+ G R+ + + + + PS + A
Sbjct: 4065 STPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPIT 4124
Query: 659 TV 660
TV
Sbjct: 4125 TV 4126
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 44.7 bits (104), Expect = 4e-04
Identities = 93/435 (21%), Positives = 162/435 (37%), Gaps = 64/435 (14%)
Query: 419 SSGVTIATSPSPASCPAGLACPSLDILASAGLGLTGLGLLGPTTLSLNTSTTPNSLLNAL 478
SS T + P S P+ + P L S + T + +TLS + T +
Sbjct: 3261 SSPPTAEGTSMPTSTPSEGSTP----LTSMPVSTTTVASSETSTLSTTPADTSTPVTTYS 3316
Query: 479 NSSVSPLQSPSSGTPSPTL--WAPPLAN---------TSSATGFSAIPHLMIPSTAQATL 527
+S SP + + P+ T + PL N +S A+ S P + ST T
Sbjct: 3317 QASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTP--VDTSTPVTTS 3374
Query: 528 TNILLSGVPTYGHTAP--SPPPGLTP-----------VDVHINSMQT---EGKKISAALN 571
T LS G + P SP G TP V +N++ T + +
Sbjct: 3375 TEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTST 3434
Query: 572 GHAQSPDIKYGA---ISTSSLGEKVLS---------ANHGDPSIQTSGSEQTSP--KSSP 617
+ SP I G ST+S G LS A+ ++ T+ + ++P SSP
Sbjct: 3435 EASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSP 3494
Query: 618 TEGCNDAFVEVGMPRSPSHSGNAGDLKQMMCPSKVSCAKRQTVELLQGTKNSHLHSTDRL 677
T MP S + G+ + + V+ ++ T+ N+ + S+ +
Sbjct: 3495 TNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQA 3554
Query: 678 LSDPELSATESPLADKKAPGSE------------RAAERAAAAQQNSERAHLAPRSSYVN 725
S P + + GS ++E + + + +R+ S+ N
Sbjct: 3555 SSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSN 3614
Query: 726 MQAFDYEQKKL-LATKAMLKKPV-VTEVRTPTNTWSGLGFSKSMPAETIKELRRANHVSY 783
E L ++T + + P+ + V T + T S G + ++P +T + + VS
Sbjct: 3615 STPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSS 3674
Query: 784 KPTMTTTYEGSSMSL 798
P T EG++M +
Sbjct: 3675 SP---VTPEGTTMPI 3686
Score = 35.4 bits (80), Expect = 0.26
Identities = 78/386 (20%), Positives = 129/386 (33%), Gaps = 37/386 (9%)
Query: 459 GPTTL-SLNTSTTPNSLLNALNSSVSPLQSPSSGTPSPTLWAPPLANTSSATGFSAIPHL 517
G T L S+ STTP A S +P+ + + T S + P ++ S +
Sbjct: 1747 GTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEG 1806
Query: 518 MIPSTAQATLTNILLSGVPTYGHTAP--SPPPGLTPVDVHINSMQTEGKKI--SAALNGH 573
M P T+ ++ + + T P S P +T V + EG I S G
Sbjct: 1807 MTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGS 1866
Query: 574 AQSPDIKYGAISTSSLGEKVLSANHGDPSIQTSGSEQTSPKSSPTEGCNDAFVEVGMPRS 633
I + +S LS S + Q S + +G + MP S
Sbjct: 1867 TALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSS-------MPTS 1919
Query: 634 PSHSGNAGDLKQMMCPSKVSCAKRQTVELLQGTKNSHLHSTDRLLSDPELSATESPLADK 693
G P S T +S +++ L+D T A
Sbjct: 1920 TPREGR---------PPLTSIPVSTTT-----VASSEINTLSTTLADTRTPVTTYSQASS 1965
Query: 694 KAPGSERAAERAAAAQQNSERAHLAPRSSYVNMQAFDYEQKKLLATKAMLKKPVV--TEV 751
++ + A + S P S+ + + + E L T P TE
Sbjct: 1966 SPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSS---EASTLSTTPVDTSTPATTSTEG 2022
Query: 752 RTPTNTWSGLGFSKSMPAETIKELRRANHVSYKPTMTTTYEGSSMSLSRSNSREHLGGGS 811
+ T G S P+E L + T+ + EG+++S + +S+ + +
Sbjct: 2023 SSSPTTAGGTSIQTSTPSERTTPLA---GMPVSTTLVVSSEGNTLSTTPVDSKTQVTNST 2079
Query: 812 ESDNWRDRNGIGPGSHSEFAASIGSP 837
E+ + G S + A S GSP
Sbjct: 2080 EASSSATAEG---SSMTISAPSEGSP 2102
Score = 35.0 bits (79), Expect = 0.34
Identities = 49/211 (23%), Positives = 86/211 (40%), Gaps = 17/211 (8%)
Query: 414 LLGLESSGVTIATSPSPASCPAGLACPSLDILASAGLGLTGLG----LLGPTTLSLNTST 469
++ + ++ VTI+ + + ++ P + P + + +T G + P+ S +T
Sbjct: 3639 IMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTT 3698
Query: 470 TPNSLLNALNSSVSPLQSPSSGTPSPTLWAPPLANTSSATGFSAIPHLMIPSTAQATLTN 529
P S +S S L +PS T +P + A +SSAT S + +P T
Sbjct: 3699 MPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTE-AISSSATLDSTTMSVSMPMEISTLGTT 3757
Query: 530 ILLSGVPTY---GHTAPSPPPGLTPVDVHINSMQTEGKKISAALNGHAQSPDIKYGAIST 586
IL+S P + PS P T + + + +EG L G P +ST
Sbjct: 3758 ILVSTTPVTRFPESSTPSIPSVYTSMSM---TTASEGSSSPTTLEGTTTMP------MST 3808
Query: 587 SSLGEKVLSANHGDPSIQTSGSEQTSPKSSP 617
+S +L+ P S SE ++ + P
Sbjct: 3809 TSERSTLLTTVLISPISVMSPSEASTLSTPP 3839
Score = 34.7 bits (78), Expect = 0.45
Identities = 86/423 (20%), Positives = 145/423 (34%), Gaps = 63/423 (14%)
Query: 386 PKPKQPSKSVIVKSVERNALNMYEARKCLLGLESSGVTIATSPSPASCPAGLACPSLDIL 445
P P +++V S E N L+ S+ + +T+ +S +L
Sbjct: 1574 PLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLL 1633
Query: 446 ASAGLGLTGLGLLGPTTLSLNTSTTPNSLLNALNSSVSPLQSPSSGTPSPTLWAPPLANT 505
S + T + +TLS + + ++ + S SP +P+ GT PT +
Sbjct: 1634 TSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSP--TPAEGTSMPT--------S 1683
Query: 506 SSATGFSAIPHLMIPSTAQATLTNILLSGVPTYGHTAPSPPPGLTPVDVHINSMQTEGKK 565
+ G + + + + +T A+ LS P T P T + + +EG
Sbjct: 1684 TYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNST-----PVTTSTEARSSPTTSEGTS 1738
Query: 566 ISAALNGHAQSPDIKYGAISTSSLGEK--VLSANHGDPSIQTSGSEQTSPKSSPTEGCND 623
+ + +P +T L + LSA D S + S + + + EG
Sbjct: 1739 MPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEG--- 1795
Query: 624 AFVEVGMPRSPSHSGNAGDLKQMMCPSKVSCAKRQTVELLQGTKNSHLHSTDRLLSDPEL 683
+P S L + M P L T SH L+++ E
Sbjct: 1796 ----TSIPTS--------TLSEGMTP-------------LTSTPVSH-----TLVANSEA 1825
Query: 684 SATESPLADKKAP--------GSERAAERAAAAQQNSERAHLAPRSSYVNMQAF-DYEQK 734
S + D +P S AE + A A S V+ E
Sbjct: 1826 STLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETN 1885
Query: 735 KLLATKAMLKKPVVTEVRTPTNTWSGLGFSKSMPAETIKELRRANHVSYKPTMTTTYEGS 794
L T A+ PV T + ++ + G SMP T +E R ++ P TTT S
Sbjct: 1886 TLSTTPAVTSTPVTTYAQVSSSPTTADG--SSMPTSTPREGRPP--LTSIPVSTTTVASS 1941
Query: 795 SMS 797
++
Sbjct: 1942 EIN 1944
Score = 34.3 bits (77), Expect = 0.58
Identities = 97/473 (20%), Positives = 166/473 (35%), Gaps = 65/473 (13%)
Query: 419 SSGVTIATS-PSPASCPAGLACPSLDILASAGLGLTGLGLLGPTTLSLNTSTTPNSLLNA 477
+ G ++ TS PS S P S +L S+ L +T + TST +
Sbjct: 732 ADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTST-HITTSTEASCSPTT 790
Query: 478 LNSSVSPLQSPSSGTPSPTLWAPPLANTSSATGFSAIPHLMIPSTAQATLTNILLSGVPT 537
+ P+ +PS G+P T +IP + P T+ T LS P
Sbjct: 791 TEGTSMPISTPSEGSPLLT----------------SIPVSITPVTSPEAST---LSTTP- 830
Query: 538 YGHTAPSPPPGLTPVDVHINSMQTEGKKISAALNGHAQSPDIKYGAISTSSLGEKVLSAN 597
S P T +V + EG + + ++P + +ST+ + +S
Sbjct: 831 ----VDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTP-LTSMPVSTTLVATSAISTL 885
Query: 598 HGDP-SIQTSGSEQTSPKSSPT--EGCNDAFVEVGMPRSPSHSGNAGDLKQMMCPSKVSC 654
P T + T +SSPT EG MP S G+ + V
Sbjct: 886 STTPVDTSTPVTNSTEARSSPTTSEG-------TSMPTSTPGEGSTPLTSMPDSTTPVVS 938
Query: 655 AKRQTVELLQGTKNSHLHSTDRLLSDPELSATESPLADKKAPGSERAAERAAAAQQNSER 714
++ +T L +T S P ++TE+ + A G+ + SE
Sbjct: 939 SEART-----------LSATPVDTSTPVTTSTEATSSPTTAEGT------SIPTSTPSEG 981
Query: 715 AHLAPRSSYVNMQAFDYEQKKLLATKAMLKKPVV--TEVRTPTNTWSGLGFSKSMPAETI 772
+ + + E L T P+ TE +P T G S P+E
Sbjct: 982 TTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGS 1041
Query: 773 KELRRANHVSYKPTMTTTYEGSSMSLSRSNSREHL---GGGSESDNWRDRNGIGPGSHSE 829
L R + TM + E S++S + +++ + S S D + ++SE
Sbjct: 1042 TPLTR---MPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSE 1098
Query: 830 FA---ASIGSPKRKQNKSTEHYLSSSNYMDCISSLTGSNGCNLNSSFKGSDLP 879
+ S+ R S LS++ I T + + ++ +G+ +P
Sbjct: 1099 GSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIP 1151
Score = 33.9 bits (76), Expect = 0.76
Identities = 53/242 (21%), Positives = 88/242 (36%), Gaps = 15/242 (6%)
Query: 386 PKPKQPSKSVIVKSVERNALNMYEARKCLLGLESSGVTIATSPSPASCPAGLACPSLDIL 445
P + P + +V S E + L+ A S+ VT + S +S A
Sbjct: 1043 PLTRMPVSTTMVASSETSTLSTTPADT------STPVTTYSQASSSSTTADGTSMPTSTY 1096
Query: 446 ASAGLGLTGLGLLGPTTLSLNTST---TPNSLLNALNSSVSPLQSPSS--GTPSPTLWAP 500
+ LT + + +S ST TP + +S SP++ GT PT +P
Sbjct: 1097 SEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPT--SP 1154
Query: 501 PLANTSSATGFSAIPHLMIPSTAQATLTNILLSGVPTYGHT-APSPPPGLTPVDVHINSM 559
P T+ L++ S A T + S T A SPPP + ++
Sbjct: 1155 PSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTP 1214
Query: 560 QTEGKKISAALNGHAQSPDIKYGAISTSSLGEKVLSANHGDPSIQTSGSEQTS-PKSSPT 618
+++ H + +STS + + S + +E TS P S+ +
Sbjct: 1215 GERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTS 1274
Query: 619 EG 620
EG
Sbjct: 1275 EG 1276
Score = 32.7 bits (73), Expect = 1.7
Identities = 83/383 (21%), Positives = 135/383 (35%), Gaps = 58/383 (15%)
Query: 417 LESSGVTIATSPSPASCPAGLACPSL-DILASAGLGLTGLGLLGPTTLS------LNTST 469
+ + G TI S +P + + PS+ + S + G PTTL ++T++
Sbjct: 3751 ISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTS 3810
Query: 470 TPNSLLNALNSSVSPLQSPSSGTPSPTLWAPPLAN-----TSSATGFSAIP------HLM 518
++LL + S + SPS + TL PP TS+ G +IP +
Sbjct: 3811 ERSTLLTTVLISPISVMSPSEAS---TLSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRIS 3867
Query: 519 IPSTAQATLTNILLS-GVPTY--GHTAPSPPP-----GLTP-VDVHINSMQTEGKKISAA 569
I S LT +L+S +PT G + S PP TP D IS +
Sbjct: 3868 ITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVS 3927
Query: 570 LNGHAQSPDIKYGAISTSSLGEKVLSANHGDPSIQTSGSEQTSPKSSPTEGCNDAFVEVG 629
+ +P +T + ++++ D T+G+ T P + TE +
Sbjct: 3928 VITEGSTPG------TTIFIPSTPVTSSTADVFPATTGAVST-PVITSTE------LNTP 3974
Query: 630 MPRSPSHSGNAGDLKQMMCPSKVSCAKRQTVELLQGTKNSHLHSTDRLLSDPELSATESP 689
S S + + K+ P+ + A V + S S LSAT +P
Sbjct: 3975 STSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATSTP 4034
Query: 690 LADKK------APGSERAAERAAAAQ---------QNSERAHLAPRSSYVNMQAFDYEQK 734
P SE + + +S + S+ VN +A
Sbjct: 4035 HTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPEAVTTMTT 4094
Query: 735 KLLATKAMLKKPVVTEVRTPTNT 757
+ + P VT PTNT
Sbjct: 4095 RTKPSTRTTSFPTVTTTAVPTNT 4117
Score = 31.6 bits (70), Expect = 3.8
Identities = 91/418 (21%), Positives = 149/418 (35%), Gaps = 64/418 (15%)
Query: 419 SSGVTIATSPSPASCPAGLACPSLDILASA-GLGLT------GLGLLG--PTTLSLNTST 469
S T++TSP S P + + +A G L G LL P + +L TS
Sbjct: 1234 SEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSP 1293
Query: 470 TPNSLLNALNSSVSPLQSPSSGTPSPTLWAPPLANTSSAT-----GFSAIPHLMIPSTAQ 524
++LL + P+ + + + SPT P TS T G + + + + +T
Sbjct: 1294 EASTLLTTPVDTKGPVVTSNEVSSSPT----PAEGTSMPTSTYSEGRTPLTSIPVNTTLV 1349
Query: 525 ATLTNILLSGVPTYGHTAPSPPPGLTPVDVHINSMQTEGKKISAALNGHAQSP--DIKYG 582
A+ +LS P T P T + + +EG + + +P I
Sbjct: 1350 ASSAISILSTTPVDNST-----PVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVS 1404
Query: 583 AISTSSLGEKVLSANHGDPSIQTSGSEQTSPKSSPT--EGCNDAFVEVGMPRSPSHSGNA 640
S LSA D S T G+ SSPT EG + +P S G
Sbjct: 1405 TTPVVSSEASTLSATPVDTS--TPGTTSAEATSSPTTAEG-------ISIPTSTPSEGKT 1455
Query: 641 GDLKQMMCPSKVSCAKRQTVELLQGTKNSHLHSTDRLLSDPELSATESPLADKKAPGSER 700
+ + V+ ++ T+ NS + ++ + S P + S + GS
Sbjct: 1456 PLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTA 1515
Query: 701 AAERAAAAQQ--NSERAHLAPRSSYVNMQAFDYEQKKLLATKA---MLKKPVVTEVRTPT 755
+ +SE L+ + + Y Q T A ++ +E TP
Sbjct: 1516 LTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPL 1575
Query: 756 NTWSGLGFSKSMPAETIKELR-RANHVSYKP-------------TMTTTYEGSSMSLS 799
S+P T+ + AN +S P + +TT EGSSM++S
Sbjct: 1576 T---------SLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTIS 1624
>gi|21735419 zinc finger, CCHC domain containing 14 [Homo sapiens]
Length = 949
Score = 44.3 bits (103), Expect = 6e-04
Identities = 51/223 (22%), Positives = 90/223 (40%), Gaps = 32/223 (14%)
Query: 759 SGLGFSKSMPAETIKE--LRRANHVSYKPTMTTTYEGSSMSLSRSNSREHLGG------- 809
SGL + S+P+ +K +RR S P + + SLS+ + + G
Sbjct: 177 SGLRYLASLPSHVLKNDHVRRFLSTSSPPQQLQSPSPGNPSLSKVGTVMGVSGRPVCGVA 236
Query: 810 -------GSESDNWRDRNGIGPGSHSEFAASIGSPKRKQNKSTEHYLSSSNYMDCISSLT 862
G++ P H A S GS L+ MD ++
Sbjct: 237 GIPSSQSGAQHHGQHPAGSAAPLPHCSHAGSAGSA-----------LAYRTQMDTSPAIL 285
Query: 863 GSNGCNLNSSFKGSDLPELFSKLGLGKYTDVFQQQEIDLQTFLTLTDQDLKELGITTFGA 922
+ + + + + + KL L KY VF+Q + ++ FL+LT++DL + T GA
Sbjct: 286 MPSSLQTPQTQEQNGILDWLRKLRLHKYYPVFKQ--LSMEKFLSLTEEDLNKFESLTMGA 343
Query: 923 RRKMLLAIS-ELNKNRRKLFESPNARTSFLEGGASGRLPRQYH 964
++K+ + E K+ R+ +P+A G + R+P H
Sbjct: 344 KKKLKTQLELEKEKSERRCL-NPSAPPLVTSSGVA-RVPPTSH 384
>gi|122937243 dual specificity phosphatase 27 [Homo sapiens]
Length = 1158
Score = 43.1 bits (100), Expect = 0.001
Identities = 109/467 (23%), Positives = 180/467 (38%), Gaps = 64/467 (13%)
Query: 401 ERNALNMYEARKCLLGLESSGVTIATSPSPASCPAGLACPSLDILASAGLGLT-GLGLLG 459
E +AL R+ L LE S T+ S S AS A + S I SA + G
Sbjct: 615 EDSALAKKRQRRLEL-LERSRQTLEESQSMASWEADSSTASGSIPLSAFWSADPSVSADG 673
Query: 460 PTTLSLNTSTTPNSLLNALNSSVSPLQSPSSGTPSPTLWAPPLANTSSATGFSAIPHLMI 519
TT L+T + + L A S+++ + + TP P L P S A+ + I +++
Sbjct: 674 DTTSVLSTQSHRSHLSQAA-SNIAGCSTSNPTTPLPNLPVGPGDTISIASIQNWIANVVS 732
Query: 520 PSTAQATLTNILLSGVPTYGHTAPSPPPGLTPVDVHINSMQTEGKKISAALNGHAQSPDI 579
+ AQ +LLS P+ P + G + L+GH
Sbjct: 733 ETLAQKQNEMLLLSRSPSVASMKAVP------------AASCLGDDQVSMLSGH------ 774
Query: 580 KYGAISTSSLGEKVLSANHGDPS--IQTSGSEQTSPKSSPTEGCNDAFVEVGMPRSPSHS 637
S+SSLG +L + PS +Q+ S T+ SSP E C P +
Sbjct: 775 -----SSSSLGGCLLPQSQARPSSDMQSVLSCNTT-LSSPAESCRSKVRGTSKPIFSLFA 828
Query: 638 GNAGDL-------KQMMCPSKVSCAKRQTVELLQGTKNSHLHSTDRLLSDPELSATESPL 690
N DL K+M + ++ + +L K S L ++ D + +
Sbjct: 829 DNV-DLKELGRKEKEMQMELREKMSEYKMEKLASDNKRSSLFKKKKVKEDEDDGVGDGDE 887
Query: 691 ADKKAPGSERAAERAAAAQQNSER-AHLAPRSSYVNMQAFDYEQKKLLATKAMLKKPVVT 749
A GS R + R+ + + ++ + LA Y + K++ ++ + T
Sbjct: 888 DTDSAIGSFRYSSRSNSQKPETDTCSSLAVCDHYASGSRVG---KEMDSSINKWLSGLRT 944
Query: 750 EVRTP-TNTWSGLGFSKSMPAETIKELRRANHVSYKPTMTTTYEGSSMSLSRSNSREHLG 808
E + P + WSG K + ++E T + SS S+S S E
Sbjct: 945 EEKPPFQSDWSGSSRGKYTRSSLLRE--------------TESKSSSYKFSKSQSEE--- 987
Query: 809 GGSESDNWRDRNGIGPGSHSEFAASI---GSPKRKQNKSTEHYLSSS 852
++ ++ + NG S S F++S G K ++ST + SSS
Sbjct: 988 --QDTSSYHEANGNSVRSTSRFSSSSTREGREMHKFSRSTYNETSSS 1032
>gi|118600983 chondroitin sulfate proteoglycan 3 [Homo sapiens]
Length = 1321
Score = 43.1 bits (100), Expect = 0.001
Identities = 56/221 (25%), Positives = 92/221 (41%), Gaps = 25/221 (11%)
Query: 416 GLESSGVTIATSPSPASCPAGLACPSLDILASAGLGLTGLGLLGPTTLSLN--TSTTPNS 473
GL+++ V P P+ GL S SA LG G+ L+ T +L +T
Sbjct: 770 GLQAT-VDEVQDPWPSVYSKGLDASS----PSAPLGSPGVFLVPKVTPNLEPWVATDEGP 824
Query: 474 LLNALNSSVSPLQSPSSGTPSPTLWAPPLANTSSATGFSAIPHLMIPSTAQATLTNILLS 533
+N ++S+V+P S +SG +W P A + P + + ++ LT +
Sbjct: 825 TVNPMDSTVTPAPSDASG-----IWEPGSQVFEEAESTTLSPQVALDTSIVTPLTTLEQG 879
Query: 534 ---GVP---TYGHTAPSPPPGLTPVDVHINSMQTEGKKISAALNGHAQSPDIKYGAISTS 587
GVP T G ++ P P P D + + T G + + P + G + +
Sbjct: 880 DKVGVPAMSTLGSSSSQPHP--EPED-QVETQGTSGASVPPHQSSPLGKPAVPPGTPTAA 936
Query: 588 SLGEKVLSANHGDPSIQTSGSEQTSPKSSPTEGCNDAFVEV 628
S+GE S + G+P++ S P T G D +EV
Sbjct: 937 SVGESA-SVSSGEPTVPWDPSSTLLP---VTLGIEDFELEV 973
>gi|147902746 MEX3A protein [Homo sapiens]
Length = 520
Score = 42.7 bits (99), Expect = 0.002
Identities = 41/154 (26%), Positives = 66/154 (42%), Gaps = 34/154 (22%)
Query: 66 AEGKGRSGEDFFQKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSV 125
AE GR G + + +TNT I P + ++P V+G++EDV A+ I+S
Sbjct: 145 AEIVGRQGCKI-KALRAKTNTYIKTPVR-------GEEPVFMVTGRREDVATARREIISA 196
Query: 126 LDTKS--------------------NRVTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCH 165
+ S +VT+++ V + V+G G IK++ ++T +
Sbjct: 197 AEHFSMIRASRNKSGAAFGVAPALPGQVTIRVRVPYRVVGLVVGPKGATIKRIQQQTNTY 256
Query: 166 IHFPDSNRNNQAEKSNQVSIAGQPAGVESARVRI 199
I P +R+ E I G P VE AR I
Sbjct: 257 IITPSRDRDPVFE------ITGAPGNVERAREEI 284
>gi|56118219 insulin-like growth factor 2 mRNA binding protein 2
isoform b [Homo sapiens]
Length = 556
Score = 42.0 bits (97), Expect = 0.003
Identities = 58/264 (21%), Positives = 100/264 (37%), Gaps = 46/264 (17%)
Query: 147 VIGKGGNNIKKVMEETGCHIHFPDSNRNNQAEKSNQVSIAGQPAGV-------------E 193
+IGK G IK + ++T + + AEK V+I P G E
Sbjct: 208 IIGKEGLTIKNITKQTQSRVDIHRKENSGAAEK--PVTIHATPEGTSEACRMILEIMQKE 265
Query: 194 SARVRIRELLPLVLMFELPIAGILQPVPDPNSPSIQHISQTYNISVSFKQRSRMYG--AT 251
+ ++ E +PL ++ + G L N I+H + T I++S Q +Y T
Sbjct: 266 ADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGT-KITISSLQDLSIYNPERT 324
Query: 252 VIVRGS-QNNTSAVKEGTAMLLEHLAGSLASAIPVSTQLDIAAQHHLF------------ 298
+ V+G+ + SA E L E + + S HH F
Sbjct: 325 ITVKGTVEACASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQ 384
Query: 299 --------------MMGRNGSNIKHIMQRTGAQIHFPDPSNPQ-KKSTVYLQGTIESVCL 343
++G+ G++IK + + GA I P + V + G E+
Sbjct: 385 EIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFK 444
Query: 344 ARQYLMGCLPLVLMFDMKEEIEVD 367
A+ + G L F+ KEE++++
Sbjct: 445 AQGRIFGKLKEENFFNPKEEVKLE 468
Score = 38.5 bits (88), Expect = 0.031
Identities = 29/132 (21%), Positives = 55/132 (41%), Gaps = 9/132 (6%)
Query: 78 QKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLDTKSNRVTLKM 137
+ I ++T +++ K GA K + + E EA MI+ ++ +++ L
Sbjct: 217 KNITKQTQSRVDIHRKENSGAAEKP---VTIHATPEGTSEACRMILEIMQKEADETKLAE 273
Query: 138 DVSHTEHSH------VIGKGGNNIKKVMEETGCHIHFPDSNRNNQAEKSNQVSIAGQPAG 191
++ +H +IGK G N+KK+ ETG I + +++ G
Sbjct: 274 EIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEA 333
Query: 192 VESARVRIRELL 203
SA + I + L
Sbjct: 334 CASAEIEIMKKL 345
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 42.0 bits (97), Expect = 0.003
Identities = 98/462 (21%), Positives = 179/462 (38%), Gaps = 61/462 (13%)
Query: 417 LESSGVTIATSPSPA-SCPAGLACPSLDILASAGLGLTGLGLLGPTT------LSLNTST 469
+ SS V AT+PSPA S +GL S +S G T TT + + S+
Sbjct: 4527 VHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSS 4586
Query: 470 TPNSLLNALNSSVSPLQSPSSGTPSP----TLWAPPLANTSSATGFSAIPHLMIPSTAQA 525
T +++ +A +++ + ++ P+S SP T P + TS + S H S+ A
Sbjct: 4587 TTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASH----SSQDA 4642
Query: 526 TLTNILLSGVPT---YGHTAPSP-PPGLTPVDVHINSMQTEG--KKISAALNGHAQSPDI 579
T T +L + T G + SP G S T G +K + + + +P
Sbjct: 4643 TGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTT 4702
Query: 580 KYGAISTSSLGEKVLSANHGDPSIQTSGSEQTSPKSSPTEGCNDAFVEVGMPRSPSHSGN 639
+ A ST+ + + H P + + SP S T G + S ++ +
Sbjct: 4703 HFSASSTTLGRSEESTTVHSSP---VATATTPSPARSTTSGL--------VEESTAYHSS 4751
Query: 640 AGDLKQMMCPSKVSCAKRQTVELLQGTKNSHLHSTDRLLSDPELSA--TESPLADKKAPG 697
G + M P + + R + ++ SH +T + S P ++ E P + +PG
Sbjct: 4752 PGSTQTMHFPESSTASGRS-----EESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPG 4806
Query: 698 S------------ERAAERAAAAQQNSERAHLAPRSSYVNMQAFDYEQKKLLATKAMLKK 745
S +E + A+ + + + P ++ E + ++
Sbjct: 4807 SIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMET 4866
Query: 746 PVVTEVRTP-TNTWSGLGFSKS-MPAETIKEL-RRANHVSYKPTMTTTYEGSSMSLSRSN 802
+ + TP + S + +S S P +T+ ++ +S +PT + S+ + +
Sbjct: 4867 TLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPA 4926
Query: 803 SREHLGGGSESDNWRDRNG-----IGPGS--HSEFAASIGSP 837
S G ES + + G + PGS S FA +P
Sbjct: 4927 STTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTP 4968
Score = 34.7 bits (78), Expect = 0.45
Identities = 111/493 (22%), Positives = 178/493 (36%), Gaps = 90/493 (18%)
Query: 419 SSGVTIATSPSPASCPAGLACPSLDILASAGLGLTGLGLLGPTTLSLNT-STTPNSLLNA 477
S G T T ++ +G + S +S+G T L T LS STT +S +
Sbjct: 3668 SPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGS 3727
Query: 478 LNSSVSPLQSPSSG-----------TPSPTLWAPPLANTSSATGFSAIPHLMIPSTAQAT 526
++++ P + SSG T SP P ++TS P L STA T
Sbjct: 3728 THTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTS--------PGLQGESTAFQT 3779
Query: 527 LTNILLSGVPTYGHTAPSPP----------------PGLTPVDVHINSMQTEGKKISAAL 570
P HT PSPP PG TP S T G + +
Sbjct: 3780 H--------PASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTI 3831
Query: 571 NGHAQSPDIKYGAISTSSLGEKVLSANHGDPSIQTSGSEQ--TSPKSSPTEGCNDAFVE- 627
SPD + SS S + GS + T P S+ T G ++A
Sbjct: 3832 --FHSSPDA--SGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTF 3887
Query: 628 VGMPRSPSHSGNAGDLKQMMCPSKVSCAKRQTVELLQGTKNSHLHSTDRLLSDPELSATE 687
PRSP+ + + + + + + ++ Q ++H + + P LS E
Sbjct: 3888 YSSPRSPTTTLSPASMTSLGVGEESTTSRSQ-------PGSTHSTVSPASTTTPGLS-EE 3939
Query: 688 SPLADKKAPGSERA-----AERAAAAQQNSERAHLAPRSSYVNMQAFDYEQKKLLATKAM 742
S +PGS + + ++ H P S++ + D +T +
Sbjct: 3940 STTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTED-------STTSG 3992
Query: 743 LKKPVVTEVRTPTNTWSGLGFSKSMPAETIKELRRANHVSYKPTMTTTYEGSSMSLSRSN 802
L + +P +T +GL PA ++ + +T G+ +S +RS
Sbjct: 3993 LTEESTAFPGSPASTQTGL------PATLTTADLGEESTTFPSSSGST--GTKLSPARST 4044
Query: 803 SREHLGGGSESDNWRDRNGIGPGSHSEFAASIGSPKRK--QNKSTEHYLSSSNYMDCIS- 859
+ +G + S + P S +E GSP KST Y S + +S
Sbjct: 4045 TSGLVGESTPS-------RLSPSS-TETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSP 4096
Query: 860 SLTGSNGCNLNSS 872
+ T S+G + SS
Sbjct: 4097 ATTTSSGVSEESS 4109
Score = 33.5 bits (75), Expect = 1.00
Identities = 71/287 (24%), Positives = 111/287 (38%), Gaps = 37/287 (12%)
Query: 417 LESSGVTIATSPSPA-SCPAGLACPSLDILASAGLGLTGLGLLGPTT------LSLNTST 469
+ SS V AT+PSPA S +GL S +S G T TT + + S+
Sbjct: 3444 VHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSS 3503
Query: 470 TPNSLLNALNSSVSPLQSPSSGTPSP----TLWAPPLANTSSATGFSAIPHLMIPSTAQA 525
T +++ +A +++ + ++ P+S SP T P + TS + S H S+ A
Sbjct: 3504 TTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASH----SSQDA 3559
Query: 526 TLTNILLSGVPT---YGHTAPSP-PPGLTPVDVHINSMQTEG-KKISAALNGHAQSPDIK 580
T T +L + T G + SP G S T G + S + +SP
Sbjct: 3560 TGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATT 3619
Query: 581 YGAISTSSLGEKVLSANHGDPSIQTSGSEQTSPKSSPTEGCNDAFVEVGMPR--SPSHSG 638
ST+S G + S + + P S+ T D+ G+ R + SHS
Sbjct: 3620 LSPASTTSSGVS-----------EESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSS 3668
Query: 639 NAGDLKQMMCPSKVSCAKRQTVELLQGTKNSHLHSTDRLLSDPELSA 685
++ S + Q T +S STD LS +A
Sbjct: 3669 PGSTDTTLLPASTTTSGSSQE----STTSHSSSGSTDTALSPGSTTA 3711
Score = 33.1 bits (74), Expect = 1.3
Identities = 53/226 (23%), Positives = 87/226 (38%), Gaps = 27/226 (11%)
Query: 419 SSGVTIATSPSPASCP-AGL--------ACPSLDILASAGLGLTGLGLLGPTTLSLNTST 469
SS ++ T+ +PAS AGL + PS + G T + TT S+
Sbjct: 1557 SSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSS 1616
Query: 470 TPNSLLNALNSSVSPLQSPSSGTPSPTLWAPPLANTSSATGFSAIPHLMIPSTAQATLTN 529
TP + +A ++++ + ++ SP L T SAT P ++ +T T
Sbjct: 1617 TPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETT 1676
Query: 530 ILLSGVPTYG--------HTAP-SPPPGLTPVDVHINSMQTE--------GKKISAALNG 572
L T G +++P SP L+P + + E G + A G
Sbjct: 1677 ALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPG 1736
Query: 573 HAQSPDI-KYGAISTSSLGEKVLSANHGDPSIQTSGSEQTSPKSSP 617
P + + S SS G + + G + + G E T+ SSP
Sbjct: 1737 STTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSP 1782
Score = 32.7 bits (73), Expect = 1.7
Identities = 65/248 (26%), Positives = 89/248 (35%), Gaps = 51/248 (20%)
Query: 419 SSGVTIATSPSPASCPAGLACPSLDILASAGLGLTGLGLLGPTTLSLNT-STTPNSLLNA 477
S G T T ++ +G + S +S+G T L T LS STT +S +
Sbjct: 1028 SPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGS 1087
Query: 478 LNSSVSPLQSPSSG-----------TPSPTLWAPPLANTSSATGFSAIPHLMIPSTAQAT 526
++++ P + SSG T SP P ++TS P L STA T
Sbjct: 1088 THTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTS--------PGLQGESTAFQT 1139
Query: 527 LTNILLSGVPTYGHTAPSPP----------------PGLTPVDVHINSMQTEGKKISAAL 570
P HT PSPP PG TP S T G + +
Sbjct: 1140 H--------PASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTI 1191
Query: 571 NGHAQSPDIKYGAISTSSLGEKVLSANHGDPSIQTSGSEQ--TSPKSSPTEGCNDAFVE- 627
SPD + SS S + GS + T P S+ T G ++A
Sbjct: 1192 --FHSSPDA--SGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTF 1247
Query: 628 VGMPRSPS 635
PRSP+
Sbjct: 1248 YSSPRSPT 1255
Score = 32.7 bits (73), Expect = 1.7
Identities = 113/493 (22%), Positives = 176/493 (35%), Gaps = 90/493 (18%)
Query: 419 SSGVTIATSPSPASCPAGLACPSLDILASAGLGLTGLGLLGPTTLSLNT-STTPNSLLNA 477
S G T T ++ +G + S +S G T L T LS STT +S +
Sbjct: 2111 SPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGS 2170
Query: 478 LNSSVSPLQSPSSG-----------TPSPTLWAPPLANTSSATGFSAIPHLMIPSTAQAT 526
++++ P + SSG T SP P ++TS P L STA T
Sbjct: 2171 THTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTS--------PGLQGESTAFQT 2222
Query: 527 LTNILLSGVPTYGHTAPSPP----------------PGLTPVDVHINSMQTEGKKISAAL 570
P HT PSPP PG TP S T G + +
Sbjct: 2223 H--------PASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTI 2274
Query: 571 NGHAQSPDIKYGAISTSSLGEKVLSANHGDPSIQTSGSEQ--TSPKSSPTEGCNDAFVE- 627
SPD + SS S + GS + T P S+ T G ++A
Sbjct: 2275 --FHSSPDA--SGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTF 2330
Query: 628 VGMPRSPSHSGNAGDLKQMMCPSKVSCAKRQTVELLQGTKNSHLHSTDRLLSDPELSATE 687
PRSP+ + + + + + + ++ Q ++H + + P LS E
Sbjct: 2331 YSSPRSPTTTLSPASMTSLGVGEESTTSRSQ-------PGSTHSTVSPASTTTPGLS-EE 2382
Query: 688 SPLADKKAPGSERAA--ERAAAAQQNSERA---HLAPRSSYVNMQAFDYEQKKLLATKAM 742
S +PGS R E H P S++ + D +T +
Sbjct: 2383 STTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTED-------STTSG 2435
Query: 743 LKKPVVTEVRTPTNTWSGLGFSKSMPAETIKELRRANHVSYKPTMTTTYEGSSMSLSRSN 802
L + +P +T +GL PA ++ + +T G+++S +RS
Sbjct: 2436 LTEESTAFPGSPASTQTGL------PATLTTADLGEESTTFPSSSGST--GTTLSPARST 2487
Query: 803 SREHLGGGSESDNWRDRNGIGPGSHSEFAASIGSPKRK--QNKSTEHYLSSSNYMDCIS- 859
+ +G + S + P S +E GSP KST Y S + +S
Sbjct: 2488 TSGLVGESTPS-------RLSPSS-TETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSP 2539
Query: 860 SLTGSNGCNLNSS 872
+ T S+G + SS
Sbjct: 2540 ATTTSSGVSEESS 2552
Score = 32.3 bits (72), Expect = 2.2
Identities = 104/477 (21%), Positives = 173/477 (36%), Gaps = 58/477 (12%)
Query: 419 SSGVTIATSPSPASCPAGLACPSLDILASAGLGLTGLGLLGPTTLSLNT-STTPNSLLNA 477
S G T T ++ +G + S +S G T L T LS STT +S +
Sbjct: 2585 SPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGS 2644
Query: 478 LNSSVSPLQSPSSG-----------TPSPTLWAPPLANTSSATGFSAIPHLMIPSTAQAT 526
++++ P + SSG T SP P ++TS + P++ T
Sbjct: 2645 THTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTT 2704
Query: 527 LTNILLSGVPTYGHTAPSPPPGLTPVDVHINSMQTEGKKISAALNGHAQSPDIKYGAIST 586
+ + P T PG TP S T G + + SPD +
Sbjct: 2705 PSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTI--FHSSPDA--SGTTP 2760
Query: 587 SSLGEKVLSANHGDPSIQTSGSEQ--TSPKSSPTEGCNDAFVE-VGMPRSPSHSGNAGDL 643
SS S + GS + T P S+ T G ++A PRSP+ + + +
Sbjct: 2761 SSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASM 2820
Query: 644 KQMMCPSKVSCAKRQTVELLQGTKNSHLHSTDRLLSDPELSATESPLADKKAPGSERAA- 702
+ + + ++ Q ++H + + P LS ES +PGS
Sbjct: 2821 TSLGVGEESTTSRSQ-------PGSTHSTVSPASTTTPGLS-EESTTVYSSSPGSTETTV 2872
Query: 703 -ERAAAAQQNSERA---HLAPRSSYVNMQAFDYEQKKLLATKAMLKKPVVTEVRTPTNTW 758
R+ E H P S++ + D +T + L + +P +T
Sbjct: 2873 FPRSTTTSVRGEEPTTFHSRPASTHTTLFTED-------STTSGLTEESTAFPGSPASTQ 2925
Query: 759 SGLGFSKSMPAETIKELRRANHVSYKPTMTTTYEGSSMSLSRSNSREHLGGGSESDNWRD 818
+GL PA ++ + +T G+++S +RS + +G + S
Sbjct: 2926 TGL------PATLTTADLGEESTTFPSSSGST--GTTLSPARSTTSGLVGESTPS----- 2972
Query: 819 RNGIGPGSHSEFAASIGSPKRK--QNKSTEHYLSSSNYMDCIS-SLTGSNGCNLNSS 872
+ P S +E GSP KST Y S + +S + T S+G + SS
Sbjct: 2973 --RLSPSS-TETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESS 3026
Score = 31.6 bits (70), Expect = 3.8
Identities = 52/226 (23%), Positives = 86/226 (38%), Gaps = 27/226 (11%)
Query: 419 SSGVTIATSPSPASCP-AGL--------ACPSLDILASAGLGLTGLGLLGPTTLSLNTST 469
SS ++ T+ +PAS AGL + PS + G T + TT S+
Sbjct: 3114 SSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSS 3173
Query: 470 TPNSLLNALNSSVSPLQSPSSGTPSPTLWAPPLANTSSATGFSAIPHLMIPSTAQATLTN 529
TP + +A ++++ + ++ SP L T SAT P ++ +T T
Sbjct: 3174 TPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETT 3233
Query: 530 ILLSGVPTYG--------HTAP-SPPPGLTPVDVHINSMQTE--------GKKISAALNG 572
L T G +++P SP L+P + + E G + A G
Sbjct: 3234 ALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPG 3293
Query: 573 HAQSPDI-KYGAISTSSLGEKVLSANHGDPSIQTSGSEQTSPKSSP 617
P + + S SS G + + G + + G E T+ S P
Sbjct: 3294 STTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGP 3339
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.359
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,509,186
Number of Sequences: 37866
Number of extensions: 1862354
Number of successful extensions: 7085
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 63
Number of HSP's successfully gapped in prelim test: 224
Number of HSP's that attempted gapping in prelim test: 6303
Number of HSP's gapped (non-prelim): 899
length of query: 974
length of database: 18,247,518
effective HSP length: 112
effective length of query: 862
effective length of database: 14,006,526
effective search space: 12073625412
effective search space used: 12073625412
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.