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Search of human proteins with 32967268
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|32967268 neurofibromin 2 isoform 8 [Homo sapiens]
(165 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|32967268 neurofibromin 2 isoform 8 [Homo sapiens] 332 9e-92
gi|32967254 neurofibromin 2 isoform 2 [Homo sapiens] 303 3e-83
gi|32967266 neurofibromin 2 isoform 2 [Homo sapiens] 303 3e-83
gi|32451486 neurofibromin 2 isoform 2 [Homo sapiens] 303 3e-83
gi|4557795 neurofibromin 2 isoform 1 [Homo sapiens] 303 3e-83
gi|32967262 neurofibromin 2 isoform 6 [Homo sapiens] 201 3e-52
gi|32967260 neurofibromin 2 isoform 5 [Homo sapiens] 193 6e-50
gi|4505257 moesin [Homo sapiens] 166 7e-42
gi|4506467 radixin [Homo sapiens] 166 7e-42
gi|161702986 ezrin [Homo sapiens] 159 8e-40
gi|21614499 ezrin [Homo sapiens] 159 8e-40
gi|32967514 neurofibromin 2 isoform 7 [Homo sapiens] 80 1e-15
gi|32967264 neurofibromin 2 isoform 7 [Homo sapiens] 80 1e-15
gi|94721308 FERM domain containing 5 isoform 2 [Homo sapiens] 77 5e-15
gi|30061491 erythrocyte membrane protein band 4.1-like 1 isoform... 74 7e-14
gi|30061489 erythrocyte membrane protein band 4.1-like 1 isoform... 74 7e-14
gi|40254949 erythrocyte membrane protein band 4.1 like 5 [Homo s... 70 1e-12
gi|38788243 myosin regulatory light chain interacting protein [H... 68 3e-12
gi|223941879 protein tyrosine phosphatase, non-receptor type 3 i... 68 4e-12
gi|223941876 protein tyrosine phosphatase, non-receptor type 3 i... 68 4e-12
gi|5031633 FERM, RhoGEF, and pleckstrin domain protein 1 isoform... 67 9e-12
gi|116063562 FERM domain containing 4A [Homo sapiens] 67 9e-12
gi|34328899 protein tyrosine phosphatase, non-receptor type 14 [... 66 1e-11
gi|110624794 erythrocyte membrane protein band 4.1 like 4B isofo... 66 1e-11
gi|110624790 erythrocyte membrane protein band 4.1 like 4B isofo... 66 1e-11
gi|34916000 FERM domain containing 7 [Homo sapiens] 66 2e-11
gi|32490572 erythrocyte membrane protein band 4.1-like 3 [Homo s... 66 2e-11
gi|4506295 protein tyrosine phosphatase, non-receptor type 4 [Ho... 65 3e-11
gi|7662310 FERM, RhoGEF and pleckstrin domain protein 2 [Homo sa... 65 3e-11
gi|87042275 erythrocyte protein band 4.1-like 4 [Homo sapiens] 64 6e-11
>gi|32967268 neurofibromin 2 isoform 8 [Homo sapiens]
Length = 165
Score = 332 bits (851), Expect = 9e-92
Identities = 165/165 (100%), Positives = 165/165 (100%)
Query: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW
Sbjct: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
Query: 61 FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL 120
FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL
Sbjct: 61 FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL 120
Query: 121 QVKKQILDEKIYCPPEASVLLASYAVQAKLTLQSAKSRVAFFEEL 165
QVKKQILDEKIYCPPEASVLLASYAVQAKLTLQSAKSRVAFFEEL
Sbjct: 121 QVKKQILDEKIYCPPEASVLLASYAVQAKLTLQSAKSRVAFFEEL 165
>gi|32967254 neurofibromin 2 isoform 2 [Homo sapiens]
Length = 590
Score = 303 bits (777), Expect = 3e-83
Identities = 149/149 (100%), Positives = 149/149 (100%)
Query: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW
Sbjct: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
Query: 61 FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL 120
FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL
Sbjct: 61 FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL 120
Query: 121 QVKKQILDEKIYCPPEASVLLASYAVQAK 149
QVKKQILDEKIYCPPEASVLLASYAVQAK
Sbjct: 121 QVKKQILDEKIYCPPEASVLLASYAVQAK 149
>gi|32967266 neurofibromin 2 isoform 2 [Homo sapiens]
Length = 590
Score = 303 bits (777), Expect = 3e-83
Identities = 149/149 (100%), Positives = 149/149 (100%)
Query: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW
Sbjct: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
Query: 61 FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL 120
FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL
Sbjct: 61 FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL 120
Query: 121 QVKKQILDEKIYCPPEASVLLASYAVQAK 149
QVKKQILDEKIYCPPEASVLLASYAVQAK
Sbjct: 121 QVKKQILDEKIYCPPEASVLLASYAVQAK 149
>gi|32451486 neurofibromin 2 isoform 2 [Homo sapiens]
Length = 590
Score = 303 bits (777), Expect = 3e-83
Identities = 149/149 (100%), Positives = 149/149 (100%)
Query: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW
Sbjct: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
Query: 61 FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL 120
FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL
Sbjct: 61 FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL 120
Query: 121 QVKKQILDEKIYCPPEASVLLASYAVQAK 149
QVKKQILDEKIYCPPEASVLLASYAVQAK
Sbjct: 121 QVKKQILDEKIYCPPEASVLLASYAVQAK 149
>gi|4557795 neurofibromin 2 isoform 1 [Homo sapiens]
Length = 595
Score = 303 bits (777), Expect = 3e-83
Identities = 149/149 (100%), Positives = 149/149 (100%)
Query: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW
Sbjct: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
Query: 61 FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL 120
FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL
Sbjct: 61 FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL 120
Query: 121 QVKKQILDEKIYCPPEASVLLASYAVQAK 149
QVKKQILDEKIYCPPEASVLLASYAVQAK
Sbjct: 121 QVKKQILDEKIYCPPEASVLLASYAVQAK 149
Score = 35.0 bits (79), Expect = 0.030
Identities = 17/17 (100%), Positives = 17/17 (100%)
Query: 149 KLTLQSAKSRVAFFEEL 165
KLTLQSAKSRVAFFEEL
Sbjct: 579 KLTLQSAKSRVAFFEEL 595
>gi|32967262 neurofibromin 2 isoform 6 [Homo sapiens]
Length = 549
Score = 201 bits (510), Expect = 3e-52
Identities = 108/149 (72%), Positives = 108/149 (72%), Gaps = 41/149 (27%)
Query: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW
Sbjct: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
Query: 61 FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL 120
FFGLQYTIKDTVAWLKMDKK
Sbjct: 61 FFGLQYTIKDTVAWLKMDKK---------------------------------------- 80
Query: 121 QVKKQILDEKIYCPPEASVLLASYAVQAK 149
VKKQILDEKIYCPPEASVLLASYAVQAK
Sbjct: 81 -VKKQILDEKIYCPPEASVLLASYAVQAK 108
>gi|32967260 neurofibromin 2 isoform 5 [Homo sapiens]
Length = 548
Score = 193 bits (490), Expect = 6e-50
Identities = 107/149 (71%), Positives = 107/149 (71%), Gaps = 42/149 (28%)
Query: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETW 60
MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCE
Sbjct: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCE---------------------- 38
Query: 61 FFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL 120
VLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL
Sbjct: 39 --------------------VLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFL 78
Query: 121 QVKKQILDEKIYCPPEASVLLASYAVQAK 149
QVKKQILDEKIYCPPEASVLLASYAVQAK
Sbjct: 79 QVKKQILDEKIYCPPEASVLLASYAVQAK 107
>gi|4505257 moesin [Homo sapiens]
Length = 577
Score = 166 bits (421), Expect = 7e-42
Identities = 82/132 (62%), Positives = 99/132 (75%), Gaps = 1/132 (0%)
Query: 19 PKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYT-IKDTVAWLKM 77
PKT +VR+ TMDAE+EF + GK LFD V +T+GLRE WFFGLQY K WLK+
Sbjct: 2 PKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLKL 61
Query: 78 DKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEA 137
+KKV DV KE P+ F F AKFYPE+ EEL+Q+ITQ LFFLQVK+ IL++ IYCPPE
Sbjct: 62 NKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPET 121
Query: 138 SVLLASYAVQAK 149
+VLLASYAVQ+K
Sbjct: 122 AVLLASYAVQSK 133
>gi|4506467 radixin [Homo sapiens]
Length = 583
Score = 166 bits (421), Expect = 7e-42
Identities = 82/132 (62%), Positives = 98/132 (74%), Gaps = 1/132 (0%)
Query: 19 PKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYT-IKDTVAWLKM 77
PK VR+ TMDAE+EF + GK LFD V +T+GLRE WFFGLQY K WLK+
Sbjct: 2 PKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLKL 61
Query: 78 DKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEA 137
+KKV DV KE P+ F F AKF+PE+ EEL+QEITQ LFFLQVK+ IL+++IYCPPE
Sbjct: 62 NKKVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPET 121
Query: 138 SVLLASYAVQAK 149
+VLLASYAVQAK
Sbjct: 122 AVLLASYAVQAK 133
>gi|161702986 ezrin [Homo sapiens]
Length = 586
Score = 159 bits (403), Expect = 8e-40
Identities = 79/132 (59%), Positives = 95/132 (71%), Gaps = 1/132 (0%)
Query: 19 PKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYTI-KDTVAWLKM 77
PK VR+ TMDAE+EF + GK LFD V +T+GLRE W+FGL Y K WLK+
Sbjct: 2 PKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLKL 61
Query: 78 DKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEA 137
DKKV +V KE P+ F F AKFYPE+ EEL+Q+ITQ LFFLQVK+ IL ++IYCPPE
Sbjct: 62 DKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPET 121
Query: 138 SVLLASYAVQAK 149
+VLL SYAVQAK
Sbjct: 122 AVLLGSYAVQAK 133
>gi|21614499 ezrin [Homo sapiens]
Length = 586
Score = 159 bits (403), Expect = 8e-40
Identities = 79/132 (59%), Positives = 95/132 (71%), Gaps = 1/132 (0%)
Query: 19 PKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYTI-KDTVAWLKM 77
PK VR+ TMDAE+EF + GK LFD V +T+GLRE W+FGL Y K WLK+
Sbjct: 2 PKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLKL 61
Query: 78 DKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEA 137
DKKV +V KE P+ F F AKFYPE+ EEL+Q+ITQ LFFLQVK+ IL ++IYCPPE
Sbjct: 62 DKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPET 121
Query: 138 SVLLASYAVQAK 149
+VLL SYAVQAK
Sbjct: 122 AVLLGSYAVQAK 133
>gi|32967514 neurofibromin 2 isoform 7 [Homo sapiens]
Length = 507
Score = 79.7 bits (195), Expect = 1e-15
Identities = 39/40 (97%), Positives = 40/40 (100%)
Query: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMK 40
MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCE+K
Sbjct: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEVK 40
Score = 62.0 bits (149), Expect = 2e-10
Identities = 33/58 (56%), Positives = 40/58 (68%)
Query: 92 VTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEASVLLASYAVQAK 149
++F L + P+ +V + F +VKKQILDEKIYCPPEASVLLASYAVQAK
Sbjct: 9 MSFSSLKRKQPKTFTVRIVTMDAEMEFNCEVKKQILDEKIYCPPEASVLLASYAVQAK 66
>gi|32967264 neurofibromin 2 isoform 7 [Homo sapiens]
Length = 507
Score = 79.7 bits (195), Expect = 1e-15
Identities = 39/40 (97%), Positives = 40/40 (100%)
Query: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMK 40
MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCE+K
Sbjct: 1 MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEVK 40
Score = 62.0 bits (149), Expect = 2e-10
Identities = 33/58 (56%), Positives = 40/58 (68%)
Query: 92 VTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEASVLLASYAVQAK 149
++F L + P+ +V + F +VKKQILDEKIYCPPEASVLLASYAVQAK
Sbjct: 9 MSFSSLKRKQPKTFTVRIVTMDAEMEFNCEVKKQILDEKIYCPPEASVLLASYAVQAK 66
>gi|94721308 FERM domain containing 5 isoform 2 [Homo sapiens]
Length = 570
Score = 77.4 bits (189), Expect = 5e-15
Identities = 49/143 (34%), Positives = 80/143 (55%), Gaps = 4/143 (2%)
Query: 9 MSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYTI 68
MS SS ++ + TVR++ D+E + KG+ LFDL+C L L E +FG+++
Sbjct: 6 MSGSSRSLEREYSCTVRLLD-DSEYTCTIQRDAKGQYLFDLLCHHLNLLEKDYFGIRFVD 64
Query: 69 KDTVA-WLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQIL 127
D WL+ K V+ + + P T F KFYP + L +EIT++L FLQ+K+ +
Sbjct: 65 PDKQRHWLEFTKSVVKQ-LRSQPPFTMCFRVKFYPADPAA-LKEEITRYLVFLQIKRDLY 122
Query: 128 DEKIYCPPEASVLLASYAVQAKL 150
++ C + LLA+Y +QA++
Sbjct: 123 HGRLLCKTSDAALLAAYILQAEI 145
>gi|30061491 erythrocyte membrane protein band 4.1-like 1 isoform b
[Homo sapiens]
Length = 779
Score = 73.6 bits (179), Expect = 7e-14
Identities = 50/146 (34%), Positives = 78/146 (53%), Gaps = 7/146 (4%)
Query: 17 KQPKTFTVRIVTMDAEMEFNCEMK--WKGKDLFDLVCRTLGLRETWFFGLQYTIKDTVA- 73
K+ K+ R+ +DA E+ CE++ +G+ LFDLVC L L E +FGL + D+
Sbjct: 30 KKYKSAICRVTLLDAS-EYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKN 88
Query: 74 WLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYC 133
WL K++ + P F F KFYP + + L ++IT++ LQ++ I+ ++ C
Sbjct: 89 WLDPSKEIKKQ--IRSSPWNFAFTVKFYPPDPAQ-LTEDITRYYLCLQLRADIITGRLPC 145
Query: 134 PPEASVLLASYAVQAKLTLQSAKSRV 159
LL SYAVQA+L A+ V
Sbjct: 146 SFVTHALLGSYAVQAELGDYDAEEHV 171
>gi|30061489 erythrocyte membrane protein band 4.1-like 1 isoform a
[Homo sapiens]
Length = 881
Score = 73.6 bits (179), Expect = 7e-14
Identities = 50/146 (34%), Positives = 78/146 (53%), Gaps = 7/146 (4%)
Query: 17 KQPKTFTVRIVTMDAEMEFNCEMK--WKGKDLFDLVCRTLGLRETWFFGLQYTIKDTVA- 73
K+ K+ R+ +DA E+ CE++ +G+ LFDLVC L L E +FGL + D+
Sbjct: 92 KKYKSAICRVTLLDAS-EYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKN 150
Query: 74 WLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYC 133
WL K++ + P F F KFYP + + L ++IT++ LQ++ I+ ++ C
Sbjct: 151 WLDPSKEIKKQ--IRSSPWNFAFTVKFYPPDPAQ-LTEDITRYYLCLQLRADIITGRLPC 207
Query: 134 PPEASVLLASYAVQAKLTLQSAKSRV 159
LL SYAVQA+L A+ V
Sbjct: 208 SFVTHALLGSYAVQAELGDYDAEEHV 233
>gi|40254949 erythrocyte membrane protein band 4.1 like 5 [Homo
sapiens]
Length = 733
Score = 69.7 bits (169), Expect = 1e-12
Identities = 44/129 (34%), Positives = 70/129 (54%), Gaps = 2/129 (1%)
Query: 23 TVRIVTMDA-EMEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYTIKDTVAWLKMDKKV 81
T R+ +D ++ + K KG++LFD + L L E+ +FGL++ VA K
Sbjct: 44 TCRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDLIESDYFGLRFMDSAQVAHWLDGTKS 103
Query: 82 LDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEASVLL 141
+ V P H KFY + L +E+T++LF LQ+K+ IL K+ CP + +V L
Sbjct: 104 IKKQVKIGSPYCLHLRVKFY-SSEPNNLREELTRYLFVLQLKQDILSGKLDCPFDTAVQL 162
Query: 142 ASYAVQAKL 150
A+Y +QA+L
Sbjct: 163 AAYNLQAEL 171
>gi|38788243 myosin regulatory light chain interacting protein [Homo
sapiens]
Length = 445
Score = 68.2 bits (165), Expect = 3e-12
Identities = 43/134 (32%), Positives = 67/134 (50%), Gaps = 4/134 (2%)
Query: 33 MEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYT-IKDTVAWLKMDKKVLDHDVSKEEP 91
ME E K G+D + VCR LG+ E +FGLQ+T K WL + ++ + P
Sbjct: 13 MEVEVEAKANGEDCLNQVCRRLGIIEVDYFGLQFTGSKGESLWLNLRNRI-SQQMDGLAP 71
Query: 92 VTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEASVLLASYAVQAKLT 151
KF+ E ++QE T+H+FFL +K+ +L + C PE +V L++ Q K
Sbjct: 72 YRLKLRVKFFVE--PHLILQEQTRHIFFLHIKEALLAGHLLCSPEQAVELSALLAQTKFG 129
Query: 152 LQSAKSRVAFFEEL 165
+ + +EEL
Sbjct: 130 DYNQNTAKYNYEEL 143
>gi|223941879 protein tyrosine phosphatase, non-receptor type 3
isoform 2 [Homo sapiens]
Length = 868
Score = 67.8 bits (164), Expect = 4e-12
Identities = 41/108 (37%), Positives = 63/108 (58%), Gaps = 4/108 (3%)
Query: 43 GKDLFDLVCRTLGLRETWFFGLQYTIK--DTVAWLKMDKKVLDHDVSKEEPVTFHFLAKF 100
G+ L D+V LG+ E +FGLQ+ D+ WL+ K + + P T HF +F
Sbjct: 51 GQVLLDMVHNHLGVTEKEYFGLQHDDDSVDSPRWLEASKAIRKQ-LKGGFPCTLHFRVRF 109
Query: 101 YPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEASVLLASYAVQA 148
+ + L QE T+HL+FLQ+K I + ++ CP ++V+LASYAVQ+
Sbjct: 110 FIPDPNT-LQQEQTRHLYFLQLKMDICEGRLTCPLNSAVVLASYAVQS 156
>gi|223941876 protein tyrosine phosphatase, non-receptor type 3
isoform 1 [Homo sapiens]
Length = 913
Score = 67.8 bits (164), Expect = 4e-12
Identities = 41/108 (37%), Positives = 63/108 (58%), Gaps = 4/108 (3%)
Query: 43 GKDLFDLVCRTLGLRETWFFGLQYTIK--DTVAWLKMDKKVLDHDVSKEEPVTFHFLAKF 100
G+ L D+V LG+ E +FGLQ+ D+ WL+ K + + P T HF +F
Sbjct: 51 GQVLLDMVHNHLGVTEKEYFGLQHDDDSVDSPRWLEASKAIRKQ-LKGGFPCTLHFRVRF 109
Query: 101 YPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEASVLLASYAVQA 148
+ + L QE T+HL+FLQ+K I + ++ CP ++V+LASYAVQ+
Sbjct: 110 FIPDPNT-LQQEQTRHLYFLQLKMDICEGRLTCPLNSAVVLASYAVQS 156
>gi|5031633 FERM, RhoGEF, and pleckstrin domain protein 1 isoform 1
[Homo sapiens]
Length = 1045
Score = 66.6 bits (161), Expect = 9e-12
Identities = 45/148 (30%), Positives = 81/148 (54%), Gaps = 11/148 (7%)
Query: 12 SSLKR--KQPKTFTVRIVTM------DAEMEFNCEMKWKGKDLFDLVCRTLGLRETWFFG 63
S+L+R K P T + ++V++ D + F + GK L D VC L L E +FG
Sbjct: 23 STLERGQKPPPTPSGKLVSIKIQMLDDTQEAFEVPQRAPGKVLLDAVCNHLNLVEGDYFG 82
Query: 64 LQYTI-KDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQV 122
L++ K WL + K ++ + + + V F+ KF+P + +L +E+T++LF LQV
Sbjct: 83 LEFPDHKKITVWLDLLKPIVKQ-IRRPKHVVVKFVVKFFPPD-HTQLQEELTRYLFALQV 140
Query: 123 KKQILDEKIYCPPEASVLLASYAVQAKL 150
K+ + ++ C ++ LL S+ VQ+++
Sbjct: 141 KQDLAQGRLTCNDTSAALLISHIVQSEI 168
>gi|116063562 FERM domain containing 4A [Homo sapiens]
Length = 1039
Score = 66.6 bits (161), Expect = 9e-12
Identities = 43/120 (35%), Positives = 63/120 (52%), Gaps = 3/120 (2%)
Query: 30 DAEMEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYTIK-DTVAWLKMDKKVLDHDVSK 88
D ++E + K K+L DLV L+E +FG+ +T + + WL++D++VL+HD K
Sbjct: 29 DRKLELLVQPKLLAKELLDLVASHFNLKEKEYFGIAFTDETGHLNWLQLDRRVLEHDFPK 88
Query: 89 EE-PVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEASVLLASYAVQ 147
+ PV +F +FY E+ L T LFFL K I E I E LASY +Q
Sbjct: 89 KSGPVVLYFCVRFYIESI-SYLKDNATIELFFLNAKSCIYKELIDVDSEVVFELASYILQ 147
>gi|34328899 protein tyrosine phosphatase, non-receptor type 14
[Homo sapiens]
Length = 1187
Score = 66.2 bits (160), Expect = 1e-11
Identities = 45/130 (34%), Positives = 72/130 (55%), Gaps = 5/130 (3%)
Query: 22 FTVRIVTMDAEM-EFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYTIKDTVA-WLKMDK 79
F RI +D+ + E ++ G++ + V + L LRET +FGL + K A W++++K
Sbjct: 21 FVTRIRLLDSNVIECTLSVESTGQECLEAVAQRLELRETHYFGLWFLSKSQQARWVELEK 80
Query: 80 KVLDH-DVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEAS 138
+ H D EP+ F F FY N L QE T++ ++LQVKK +L+ ++ C +
Sbjct: 81 PLKKHLDKFANEPLLF-FGVMFYVPNVSW-LQQEATRYQYYLQVKKDVLEGRLRCTLDQV 138
Query: 139 VLLASYAVQA 148
+ LA AVQA
Sbjct: 139 IRLAGLAVQA 148
>gi|110624794 erythrocyte membrane protein band 4.1 like 4B isoform
1 [Homo sapiens]
Length = 518
Score = 66.2 bits (160), Expect = 1e-11
Identities = 44/131 (33%), Positives = 66/131 (50%), Gaps = 2/131 (1%)
Query: 21 TFTVRIVTMDA-EMEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYTIKDTVAWLKMDK 79
T R+ +D E+ + KG+DLFD + L L ET +FGLQ+ VA
Sbjct: 84 TLYCRVFLLDGTEVSVDLPKHAKGQDLFDQIVYHLDLVETDYFGLQFLDSAQVAHWLDHA 143
Query: 80 KVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEASV 139
K + + HF K+Y + L +E T++LF LQ++ IL K+ CP E +V
Sbjct: 144 KPIKKQMKIGPAYALHFRVKYY-SSEPNNLREEFTRYLFVLQLRHDILSGKLKCPYETAV 202
Query: 140 LLASYAVQAKL 150
LA+ +QA+L
Sbjct: 203 ELAALCLQAEL 213
>gi|110624790 erythrocyte membrane protein band 4.1 like 4B isoform
2 [Homo sapiens]
Length = 900
Score = 66.2 bits (160), Expect = 1e-11
Identities = 44/131 (33%), Positives = 66/131 (50%), Gaps = 2/131 (1%)
Query: 21 TFTVRIVTMDA-EMEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYTIKDTVAWLKMDK 79
T R+ +D E+ + KG+DLFD + L L ET +FGLQ+ VA
Sbjct: 84 TLYCRVFLLDGTEVSVDLPKHAKGQDLFDQIVYHLDLVETDYFGLQFLDSAQVAHWLDHA 143
Query: 80 KVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEASV 139
K + + HF K+Y + L +E T++LF LQ++ IL K+ CP E +V
Sbjct: 144 KPIKKQMKIGPAYALHFRVKYY-SSEPNNLREEFTRYLFVLQLRHDILSGKLKCPYETAV 202
Query: 140 LLASYAVQAKL 150
LA+ +QA+L
Sbjct: 203 ELAALCLQAEL 213
>gi|34916000 FERM domain containing 7 [Homo sapiens]
Length = 714
Score = 65.9 bits (159), Expect = 2e-11
Identities = 38/122 (31%), Positives = 68/122 (55%), Gaps = 3/122 (2%)
Query: 30 DAEMEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQY-TIKDTVAWLKMDKKVLDHDVSK 88
D++ F + K GK LF+L C L L E +FGL++ + WL++ K + V
Sbjct: 11 DSQKIFVVDQKSSGKALFNLSCSHLNLAEKEYFGLEFCSHSGNNVWLELLKPITKQ-VKN 69
Query: 89 EEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEASVLLASYAVQA 148
+ + F F+ KF+P + L +E+T++LF LQ+KK + ++ C + L+ S+ +Q+
Sbjct: 70 PKEIVFKFMVKFFPVDPGH-LREELTRYLFTLQIKKDLALGRLPCSDNCTALMVSHILQS 128
Query: 149 KL 150
+L
Sbjct: 129 EL 130
>gi|32490572 erythrocyte membrane protein band 4.1-like 3 [Homo
sapiens]
Length = 1087
Score = 65.9 bits (159), Expect = 2e-11
Identities = 48/149 (32%), Positives = 80/149 (53%), Gaps = 8/149 (5%)
Query: 6 ASRMSFSSLKR-KQPKTFTVRIVTMDAEMEFNC--EMKWKGKDLFDLVCRTLGLRETWFF 62
+S++S S LK K+PK+ +++ +D E+ C E + +G+ LFD VC L L E +F
Sbjct: 93 SSKLSRSPLKIVKKPKSMQCKVILLDGS-EYTCDVEKRSRGQVLFDKVCEHLNLLEKDYF 151
Query: 63 GLQY-TIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQ 121
GL Y ++ WL K++ + F F KFYP + +L ++IT++ LQ
Sbjct: 152 GLTYRDAENQKNWLDPAKEIKKQ--VRSGAWHFSFNVKFYPPD-PAQLSEDITRYYLCLQ 208
Query: 122 VKKQILDEKIYCPPEASVLLASYAVQAKL 150
++ I+ ++ C LL SY VQ++L
Sbjct: 209 LRDDIVSGRLPCSFVTLALLGSYTVQSEL 237
>gi|4506295 protein tyrosine phosphatase, non-receptor type 4 [Homo
sapiens]
Length = 926
Score = 65.1 bits (157), Expect = 3e-11
Identities = 46/143 (32%), Positives = 77/143 (53%), Gaps = 6/143 (4%)
Query: 12 SSLKRKQPKTFTV-RIVTMDAEME-FNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYT-- 67
S L R + T V I+ +D ++ F +G+ L D+V + L L E +FGLQ
Sbjct: 18 SELARDRQHTEVVCNILLLDNTVQAFKVNKHDQGQVLLDVVFKHLDLTEQDYFGLQLADD 77
Query: 68 IKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQIL 127
D WL +K + + + P + +F KF+ + + L +E T++ +FLQ+K+ IL
Sbjct: 78 STDNPRWLDPNKPIRKQ-LKRGSPYSLNFRVKFFVSDPNK-LQEEYTRYQYFLQIKQDIL 135
Query: 128 DEKIYCPPEASVLLASYAVQAKL 150
++ CP + LLAS+AVQ++L
Sbjct: 136 TGRLPCPSNTAALLASFAVQSEL 158
>gi|7662310 FERM, RhoGEF and pleckstrin domain protein 2 [Homo
sapiens]
Length = 1054
Score = 64.7 bits (156), Expect = 3e-11
Identities = 41/139 (29%), Positives = 76/139 (54%), Gaps = 4/139 (2%)
Query: 14 LKRKQPKTFTVRIVTMDAEME-FNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYTIKDTV 72
L R Q K +R+ +D ME F+ E K G+ L V + L L E +FG+++ +
Sbjct: 36 LPRMQEKHLHLRVKLLDNTMEIFDIEPKCDGQVLLTQVWKRLNLVECDYFGMEFQNTQSY 95
Query: 73 -AWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKI 131
WL+ K ++ + + + V KF+P + + L +E T++LF LQ+K+ +L+E++
Sbjct: 96 WIWLEPMKPII-RQIRRPKNVVLRLAVKFFPPDPGQ-LQEEYTRYLFALQLKRDLLEERL 153
Query: 132 YCPPEASVLLASYAVQAKL 150
C + LL S+ +Q+++
Sbjct: 154 TCADTTAALLTSHLLQSEI 172
>gi|87042275 erythrocyte protein band 4.1-like 4 [Homo sapiens]
Length = 686
Score = 63.9 bits (154), Expect = 6e-11
Identities = 39/112 (34%), Positives = 63/112 (56%), Gaps = 4/112 (3%)
Query: 42 KGKDLFDLVCRTLGLRETWFFGLQYTIKD-TVAWLKMDKKVLDHD--VSKEEPVTFHFLA 98
KG + D V + L E +FGL+Y + WL K + +H ++ P T +F
Sbjct: 37 KGSVVLDHVFHHVNLVEIDYFGLRYCDRSHQTYWLDPAKTLAEHKELINTGPPYTLYFGI 96
Query: 99 KFYPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEASVLLASYAVQAKL 150
KFY E+ + L +EIT++ FFLQVK+ +L ++ CP + L +YA+Q++L
Sbjct: 97 KFYAEDPCK-LKEEITRYQFFLQVKQDVLQGRLPCPVNTAAQLGAYAIQSEL 147
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.134 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,610,318
Number of Sequences: 37866
Number of extensions: 218435
Number of successful extensions: 584
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 52
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 487
Number of HSP's gapped (non-prelim): 65
length of query: 165
length of database: 18,247,518
effective HSP length: 94
effective length of query: 71
effective length of database: 14,688,114
effective search space: 1042856094
effective search space used: 1042856094
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.