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Search of human proteins with 32483374
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|32483374 nucleolar protein 5A [Homo sapiens]
(594 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|32483374 nucleolar protein 5A [Homo sapiens] 1147 0.0
gi|7706254 NOP58 ribonucleoprotein homolog [Homo sapiens] 345 7e-95
gi|169183877 PREDICTED: similar to hCG1742476 [Homo sapiens] 325 7e-89
gi|169179771 PREDICTED: similar to hCG1742476 [Homo sapiens] 325 7e-89
gi|239743692 PREDICTED: hypothetical protein LOC402360 [Homo sap... 325 7e-89
gi|169204941 PREDICTED: similar to Nucleolar protein 5A [Homo sa... 215 1e-55
gi|169205573 PREDICTED: similar to Nucleolar protein 5A [Homo sa... 215 1e-55
gi|169203848 PREDICTED: hypothetical protein [Homo sapiens] 215 1e-55
gi|221136939 pre-mRNA processing factor 31 homolog [Homo sapiens] 122 7e-28
gi|27734775 hypothetical protein LOC286499 [Homo sapiens] 65 2e-10
gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens] 59 1e-08
gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens] 59 1e-08
gi|12711674 UPF3 regulator of nonsense transcripts homolog B iso... 57 5e-08
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 55 2e-07
gi|18375528 UPF3 regulator of nonsense transcripts homolog B iso... 55 2e-07
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 54 5e-07
gi|40068059 CBF1 interacting corepressor [Homo sapiens] 53 7e-07
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do... 49 1e-05
gi|157738619 smoothelin-like 1 [Homo sapiens] 49 1e-05
gi|118498359 ribosomal L1 domain containing 1 [Homo sapiens] 49 2e-05
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 48 2e-05
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 48 2e-05
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 48 2e-05
gi|151301228 formin binding protein 3 [Homo sapiens] 48 2e-05
gi|221219020 NYD-SP11 protein [Homo sapiens] 47 4e-05
gi|50962817 TWIST neighbor [Homo sapiens] 47 4e-05
gi|125656165 THO complex 2 [Homo sapiens] 47 5e-05
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 47 5e-05
gi|95147555 microtubule-associated protein 1A [Homo sapiens] 47 5e-05
gi|7661950 SH2 domain binding protein 1 [Homo sapiens] 47 5e-05
>gi|32483374 nucleolar protein 5A [Homo sapiens]
Length = 594
Score = 1147 bits (2968), Expect = 0.0
Identities = 594/594 (100%), Positives = 594/594 (100%)
Query: 1 MVLLHVLFEHAVGYALLALKEVEEISLLQPQVEESVLNLGKFHSIVRLVAFCPFASSQVA 60
MVLLHVLFEHAVGYALLALKEVEEISLLQPQVEESVLNLGKFHSIVRLVAFCPFASSQVA
Sbjct: 1 MVLLHVLFEHAVGYALLALKEVEEISLLQPQVEESVLNLGKFHSIVRLVAFCPFASSQVA 60
Query: 61 LENANAVSEGVVHEDLRLLLETHLPSKKKKVLLGVGDPKIGAAIQEELGYNCQTGGVIAE 120
LENANAVSEGVVHEDLRLLLETHLPSKKKKVLLGVGDPKIGAAIQEELGYNCQTGGVIAE
Sbjct: 61 LENANAVSEGVVHEDLRLLLETHLPSKKKKVLLGVGDPKIGAAIQEELGYNCQTGGVIAE 120
Query: 121 ILRGVRLHFHNLVKGLTDLSACKAQLGLGHSYSRAKVKFNVNRVDNMIIQSISLLDQLDK 180
ILRGVRLHFHNLVKGLTDLSACKAQLGLGHSYSRAKVKFNVNRVDNMIIQSISLLDQLDK
Sbjct: 121 ILRGVRLHFHNLVKGLTDLSACKAQLGLGHSYSRAKVKFNVNRVDNMIIQSISLLDQLDK 180
Query: 181 DINTFSMRVREWYGYHFPELVKIINDNATYCRLAQFIGNRRELNEDKLEKLEELTMDGAK 240
DINTFSMRVREWYGYHFPELVKIINDNATYCRLAQFIGNRRELNEDKLEKLEELTMDGAK
Sbjct: 181 DINTFSMRVREWYGYHFPELVKIINDNATYCRLAQFIGNRRELNEDKLEKLEELTMDGAK 240
Query: 241 AKAILDASRSSMGMDISAIDLINIESFSSRVVSLSEYRQSLHTYLRSKMSQVAPSLSALI 300
AKAILDASRSSMGMDISAIDLINIESFSSRVVSLSEYRQSLHTYLRSKMSQVAPSLSALI
Sbjct: 241 AKAILDASRSSMGMDISAIDLINIESFSSRVVSLSEYRQSLHTYLRSKMSQVAPSLSALI 300
Query: 301 GEAVGARLIAHAGSLTNLAKYPASTVQILGAEKALFRALKTRGNTPKYGLIFHSTFIGRA 360
GEAVGARLIAHAGSLTNLAKYPASTVQILGAEKALFRALKTRGNTPKYGLIFHSTFIGRA
Sbjct: 301 GEAVGARLIAHAGSLTNLAKYPASTVQILGAEKALFRALKTRGNTPKYGLIFHSTFIGRA 360
Query: 361 AAKNKGRISRYLANKCSIASRIDCFSEVPTSVFGEKLREQVEERLSFYETGEIPRKNLDV 420
AAKNKGRISRYLANKCSIASRIDCFSEVPTSVFGEKLREQVEERLSFYETGEIPRKNLDV
Sbjct: 361 AAKNKGRISRYLANKCSIASRIDCFSEVPTSVFGEKLREQVEERLSFYETGEIPRKNLDV 420
Query: 421 MKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRLAALALASSENSSSTPEECEEMSEKPK 480
MKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRLAALALASSENSSSTPEECEEMSEKPK
Sbjct: 421 MKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRLAALALASSENSSSTPEECEEMSEKPK 480
Query: 481 KKKKQKPQEVPQENGMEDPSISFSKPKKKKSFSKEELMSSDLEETAGSTSIPKRKKSTPK 540
KKKKQKPQEVPQENGMEDPSISFSKPKKKKSFSKEELMSSDLEETAGSTSIPKRKKSTPK
Sbjct: 481 KKKKQKPQEVPQENGMEDPSISFSKPKKKKSFSKEELMSSDLEETAGSTSIPKRKKSTPK 540
Query: 541 EETVNDPEEAGHRSGSKKKRKFSKEEPVSSGPEEAVGKSSSKKKKKFHKASQED 594
EETVNDPEEAGHRSGSKKKRKFSKEEPVSSGPEEAVGKSSSKKKKKFHKASQED
Sbjct: 541 EETVNDPEEAGHRSGSKKKRKFSKEEPVSSGPEEAVGKSSSKKKKKFHKASQED 594
>gi|7706254 NOP58 ribonucleoprotein homolog [Homo sapiens]
Length = 529
Score = 345 bits (885), Expect = 7e-95
Identities = 213/550 (38%), Positives = 322/550 (58%), Gaps = 32/550 (5%)
Query: 6 VLFEHAVGYALLAL---KEVEEISLLQPQVEESVLNLGKFHSIVRLVAFCPFASSQVALE 62
VLFE +VGYA+ + K+++E+ L + E K + IV+L F F + AL
Sbjct: 3 VLFETSVGYAIFKVLNEKKLQEVDSLWKEFETPE----KANKIVKLKHFEKFQDTAEALA 58
Query: 63 NANAVSEGVVHEDLRLLLETHLPSKKKKVLLGVGDPKIGAAIQEELGYNCQTGGVIAEIL 122
A+ EG +++ L+ +L+ + K+ L V D K+G I+E+L +C V+ E++
Sbjct: 59 AFTALMEGKINKQLKKVLKKIV--KEAHEPLAVADAKLGGVIKEKLNLSCIHSPVVNELM 116
Query: 123 RGVRLHFHNLVKGLTDLSACKAQLGLGHSYSRAKVKFNVNRVDNMIIQSISLLDQLDKDI 182
RG+R L+ G+ LGL HS SR ++KF+ ++VD MI+Q+ISLLD LDK++
Sbjct: 117 RGIRSQMDGLIPGVEPREMAAMCLGLAHSLSRYRLKFSADKVDTMIVQAISLLDDLDKEL 176
Query: 183 NTFSMRVREWYGYHFPELVKIINDNATYCRLAQFIGNRRELNEDKLEKLEELTMDGAKAK 242
N + MR REWYG+HFPEL KII+DN TYC+ Q +G+R+ KL +L ++ A+ K
Sbjct: 177 NNYIMRCREWYGWHFPELGKIISDNLTYCKCLQKVGDRKNYASAKLSELLPEEVE-AEVK 235
Query: 243 AILDASRSSMGMDISAIDLINIESFSSRVVSLSEYRQSLHTYLRSKMSQVAPSLSALIGE 302
A A+ SMG ++S D+ NI ++V+ +SEYR L+ YL+++M +AP+++ ++GE
Sbjct: 236 A---AAEISMGTEVSEEDICNILHLCTQVIEISEYRTQLYEYLQNRMMAIAPNVTVMVGE 292
Query: 303 AVGARLIAHAGSLTNLAKYPASTVQILGAEKALFRALKTRGNTPKYGLIFHSTFIGRAAA 362
VGARLIAHAGSL NLAK+ ASTVQILGAEKALFRALK+R +TPKYGLI+H++ +G+ +
Sbjct: 293 LVGARLIAHAGSLLNLAKHAASTVQILGAEKALFRALKSRRDTPKYGLIYHASLVGQTSP 352
Query: 363 KNKGRISRYLANKCSIASRIDCFSEVPTSVFGEKLREQVEERLSFYETGEIPRKNLDVMK 422
K+KG+ISR LA K +A R D F E +S G + R ++E RL ++
Sbjct: 353 KHKGKISRMLAAKTVLAIRYDAFGEDSSSAMGVENRAKLEARLR-------------TLE 399
Query: 423 EAMVQAEEAAAEITRKLEKQEKKRLKK--EKKRLAALALASSENSSSTPEECEEMSEKPK 480
+ ++ + K EK E K K + + L S + ++ +E++EK
Sbjct: 400 DRGIRKISGTGKALAKTEKYEHKSEVKTYDPSGDSTLPTCSKKRKIEQVDKEDEITEKKA 459
Query: 481 KKK--KQKPQEVPQENGMEDPSISFSKPKK--KKSFSKEELMSSDLEETAGSTSIPKRKK 536
KK K K +E +E E+ S K KK KK KEE +S + T+ + + P++KK
Sbjct: 460 KKAKIKVKVEEEEEEKVAEEEETSVKKKKKRGKKKHIKEEPLSEEEPCTSTAIASPEKKK 519
Query: 537 STPKEETVND 546
K+ D
Sbjct: 520 KKKKKRENED 529
>gi|169183877 PREDICTED: similar to hCG1742476 [Homo sapiens]
Length = 278
Score = 325 bits (833), Expect = 7e-89
Identities = 175/258 (67%), Positives = 199/258 (77%), Gaps = 28/258 (10%)
Query: 341 TRGNTPKYGLIFHSTFIGRAAAKNKGRISRYLANKCSIASRIDCFSEVPTSVFGEKLREQ 400
T+GNTPKYGL+FHSTF G+AAA+NKGRIS+YLANKCSIAS+IDCF+EV S+FGEKL+EQ
Sbjct: 2 TKGNTPKYGLVFHSTFTGQAAARNKGRISQYLANKCSIASQIDCFAEVLMSIFGEKLQEQ 61
Query: 401 VEERLSFYETGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRLAALALA 460
VEERLSFYETGEI K +DVMK MVQAE+ AAEI RKLEKQE
Sbjct: 62 VEERLSFYETGEILSKKMDVMKTEMVQAEKTAAEIIRKLEKQE----------------- 104
Query: 461 SSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGMEDPSISFSKPKKKKSFSKEELMSS 520
TPEEC + S KPKKKKKQKPQE PQENG++DPS SFSKP K+KSFSKE+L+SS
Sbjct: 105 -------TPEECAKTSVKPKKKKKQKPQEAPQENGIKDPSNSFSKPNKRKSFSKEKLVSS 157
Query: 521 DLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGSKKKRKFS---KEEPVSSGPEEAVG 577
EETAGS S+P RK S+PKEE VNDP+EAG+RS +KKK S ++E VSSGPEEA G
Sbjct: 158 HREETAGSISLPNRKTSSPKEEAVNDPKEAGNRSVTKKKTGNSPSKRKELVSSGPEEAAG 217
Query: 578 -KSSSKKKKKFHKASQED 594
KSSSKKKKK HK QED
Sbjct: 218 SKSSSKKKKKLHKVPQED 235
Score = 29.6 bits (65), Expect = 8.2
Identities = 35/115 (30%), Positives = 45/115 (39%), Gaps = 16/115 (13%)
Query: 414 PRKNLDVMKEAMVQA--EEAAAEIT---RKLE--KQEKKRLKKE-------KKRLAALAL 459
P K KE +V + EE A I+ RK K+E KE KK+
Sbjct: 143 PNKRKSFSKEKLVSSHREETAGSISLPNRKTSSPKEEAVNDPKEAGNRSVTKKKTGNSPS 202
Query: 460 ASSENSSSTPEEC--EEMSEKPKKKKKQKPQEVPQENGMEDPSISFSKPKKKKSF 512
E SS PEE + S K KKK + PQE NG + P++ F
Sbjct: 203 KRKELVSSGPEEAAGSKSSSKKKKKLHKVPQEDESANGRPPSGGAHPTPRRHFPF 257
>gi|169179771 PREDICTED: similar to hCG1742476 [Homo sapiens]
Length = 278
Score = 325 bits (833), Expect = 7e-89
Identities = 175/258 (67%), Positives = 199/258 (77%), Gaps = 28/258 (10%)
Query: 341 TRGNTPKYGLIFHSTFIGRAAAKNKGRISRYLANKCSIASRIDCFSEVPTSVFGEKLREQ 400
T+GNTPKYGL+FHSTF G+AAA+NKGRIS+YLANKCSIAS+IDCF+EV S+FGEKL+EQ
Sbjct: 2 TKGNTPKYGLVFHSTFTGQAAARNKGRISQYLANKCSIASQIDCFAEVLMSIFGEKLQEQ 61
Query: 401 VEERLSFYETGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRLAALALA 460
VEERLSFYETGEI K +DVMK MVQAE+ AAEI RKLEKQE
Sbjct: 62 VEERLSFYETGEILSKKMDVMKTEMVQAEKTAAEIIRKLEKQE----------------- 104
Query: 461 SSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGMEDPSISFSKPKKKKSFSKEELMSS 520
TPEEC + S KPKKKKKQKPQE PQENG++DPS SFSKP K+KSFSKE+L+SS
Sbjct: 105 -------TPEECAKTSVKPKKKKKQKPQEAPQENGIKDPSNSFSKPNKRKSFSKEKLVSS 157
Query: 521 DLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGSKKKRKFS---KEEPVSSGPEEAVG 577
EETAGS S+P RK S+PKEE VNDP+EAG+RS +KKK S ++E VSSGPEEA G
Sbjct: 158 HREETAGSISLPNRKTSSPKEEAVNDPKEAGNRSVTKKKTGNSPSKRKELVSSGPEEAAG 217
Query: 578 -KSSSKKKKKFHKASQED 594
KSSSKKKKK HK QED
Sbjct: 218 SKSSSKKKKKLHKVPQED 235
Score = 29.6 bits (65), Expect = 8.2
Identities = 35/115 (30%), Positives = 45/115 (39%), Gaps = 16/115 (13%)
Query: 414 PRKNLDVMKEAMVQA--EEAAAEIT---RKLE--KQEKKRLKKE-------KKRLAALAL 459
P K KE +V + EE A I+ RK K+E KE KK+
Sbjct: 143 PNKRKSFSKEKLVSSHREETAGSISLPNRKTSSPKEEAVNDPKEAGNRSVTKKKTGNSPS 202
Query: 460 ASSENSSSTPEEC--EEMSEKPKKKKKQKPQEVPQENGMEDPSISFSKPKKKKSF 512
E SS PEE + S K KKK + PQE NG + P++ F
Sbjct: 203 KRKELVSSGPEEAAGSKSSSKKKKKLHKVPQEDESANGRPPSGGAHPTPRRHFPF 257
>gi|239743692 PREDICTED: hypothetical protein LOC402360 [Homo
sapiens]
Length = 278
Score = 325 bits (833), Expect = 7e-89
Identities = 175/258 (67%), Positives = 199/258 (77%), Gaps = 28/258 (10%)
Query: 341 TRGNTPKYGLIFHSTFIGRAAAKNKGRISRYLANKCSIASRIDCFSEVPTSVFGEKLREQ 400
T+GNTPKYGL+FHSTF G+AAA+NKGRIS+YLANKCSIAS+IDCF+EV S+FGEKL+EQ
Sbjct: 2 TKGNTPKYGLVFHSTFTGQAAARNKGRISQYLANKCSIASQIDCFAEVLMSIFGEKLQEQ 61
Query: 401 VEERLSFYETGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRLAALALA 460
VEERLSFYETGEI K +DVMK MVQAE+ AAEI RKLEKQE
Sbjct: 62 VEERLSFYETGEILSKKMDVMKTEMVQAEKTAAEIIRKLEKQE----------------- 104
Query: 461 SSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGMEDPSISFSKPKKKKSFSKEELMSS 520
TPEEC + S KPKKKKKQKPQE PQENG++DPS SFSKP K+KSFSKE+L+SS
Sbjct: 105 -------TPEECAKTSVKPKKKKKQKPQEAPQENGIKDPSNSFSKPNKRKSFSKEKLVSS 157
Query: 521 DLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGSKKKRKFS---KEEPVSSGPEEAVG 577
EETAGS S+P RK S+PKEE VNDP+EAG+RS +KKK S ++E VSSGPEEA G
Sbjct: 158 HREETAGSISLPNRKTSSPKEEAVNDPKEAGNRSVTKKKTGNSPSKRKELVSSGPEEAAG 217
Query: 578 -KSSSKKKKKFHKASQED 594
KSSSKKKKK HK QED
Sbjct: 218 SKSSSKKKKKLHKVPQED 235
Score = 29.6 bits (65), Expect = 8.2
Identities = 35/115 (30%), Positives = 45/115 (39%), Gaps = 16/115 (13%)
Query: 414 PRKNLDVMKEAMVQA--EEAAAEIT---RKLE--KQEKKRLKKE-------KKRLAALAL 459
P K KE +V + EE A I+ RK K+E KE KK+
Sbjct: 143 PNKRKSFSKEKLVSSHREETAGSISLPNRKTSSPKEEAVNDPKEAGNRSVTKKKTGNSPS 202
Query: 460 ASSENSSSTPEEC--EEMSEKPKKKKKQKPQEVPQENGMEDPSISFSKPKKKKSF 512
E SS PEE + S K KKK + PQE NG + P++ F
Sbjct: 203 KRKELVSSGPEEAAGSKSSSKKKKKLHKVPQEDESANGRPPSGGAHPTPRRHFPF 257
>gi|169204941 PREDICTED: similar to Nucleolar protein 5A [Homo
sapiens]
Length = 166
Score = 215 bits (547), Expect = 1e-55
Identities = 111/131 (84%), Positives = 116/131 (88%), Gaps = 1/131 (0%)
Query: 464 NSSSTPEECEEMSEKPKKKKKQKPQEVPQENGMEDPSISFSKPKKKKSFSKEELMSSDLE 523
+SSSTPE CEE SEKPKKKKKQKPQEVPQE EDPSISFSKPKKKKSFSKEELMSSDLE
Sbjct: 37 DSSSTPERCEETSEKPKKKKKQKPQEVPQEK-TEDPSISFSKPKKKKSFSKEELMSSDLE 95
Query: 524 ETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGSKKKRKFSKEEPVSSGPEEAVGKSSSKK 583
ETAGSTS+ KRKKS+PK ETVNDPEEAG+RS SKKK KFSKEEPVSSGPEEA G SS K
Sbjct: 96 ETAGSTSLLKRKKSSPKTETVNDPEEAGNRSVSKKKTKFSKEEPVSSGPEEAAGSKSSSK 155
Query: 584 KKKFHKASQED 594
KK FHK +QED
Sbjct: 156 KKMFHKEAQED 166
Score = 32.3 bits (72), Expect = 1.3
Identities = 33/117 (28%), Positives = 52/117 (44%), Gaps = 11/117 (9%)
Query: 409 ETGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKKRLKKE------KKRLAALALASS 462
ET E P+K + + Q + I+ K++K K+E ++ + +L
Sbjct: 47 ETSEKPKKKKKQKPQEVPQEKTEDPSISFSKPKKKKSFSKEELMSSDLEETAGSTSLLKR 106
Query: 463 ENSS---STPEECEEMSEKPKKKKKQK-PQEVPQENGMEDPSISFSKPKKKKSFSKE 515
+ SS T + EE + KKK K +E P +G E+ + S S KKK F KE
Sbjct: 107 KKSSPKTETVNDPEEAGNRSVSKKKTKFSKEEPVSSGPEEAAGSKSS-SKKKMFHKE 162
>gi|169205573 PREDICTED: similar to Nucleolar protein 5A [Homo
sapiens]
Length = 166
Score = 215 bits (547), Expect = 1e-55
Identities = 111/131 (84%), Positives = 116/131 (88%), Gaps = 1/131 (0%)
Query: 464 NSSSTPEECEEMSEKPKKKKKQKPQEVPQENGMEDPSISFSKPKKKKSFSKEELMSSDLE 523
+SSSTPE CEE SEKPKKKKKQKPQEVPQE EDPSISFSKPKKKKSFSKEELMSSDLE
Sbjct: 37 DSSSTPERCEETSEKPKKKKKQKPQEVPQEK-TEDPSISFSKPKKKKSFSKEELMSSDLE 95
Query: 524 ETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGSKKKRKFSKEEPVSSGPEEAVGKSSSKK 583
ETAGSTS+ KRKKS+PK ETVNDPEEAG+RS SKKK KFSKEEPVSSGPEEA G SS K
Sbjct: 96 ETAGSTSLLKRKKSSPKTETVNDPEEAGNRSVSKKKTKFSKEEPVSSGPEEAAGSKSSSK 155
Query: 584 KKKFHKASQED 594
KK FHK +QED
Sbjct: 156 KKMFHKEAQED 166
Score = 32.3 bits (72), Expect = 1.3
Identities = 33/117 (28%), Positives = 52/117 (44%), Gaps = 11/117 (9%)
Query: 409 ETGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKKRLKKE------KKRLAALALASS 462
ET E P+K + + Q + I+ K++K K+E ++ + +L
Sbjct: 47 ETSEKPKKKKKQKPQEVPQEKTEDPSISFSKPKKKKSFSKEELMSSDLEETAGSTSLLKR 106
Query: 463 ENSS---STPEECEEMSEKPKKKKKQK-PQEVPQENGMEDPSISFSKPKKKKSFSKE 515
+ SS T + EE + KKK K +E P +G E+ + S S KKK F KE
Sbjct: 107 KKSSPKTETVNDPEEAGNRSVSKKKTKFSKEEPVSSGPEEAAGSKSS-SKKKMFHKE 162
>gi|169203848 PREDICTED: hypothetical protein [Homo sapiens]
Length = 166
Score = 215 bits (547), Expect = 1e-55
Identities = 111/131 (84%), Positives = 116/131 (88%), Gaps = 1/131 (0%)
Query: 464 NSSSTPEECEEMSEKPKKKKKQKPQEVPQENGMEDPSISFSKPKKKKSFSKEELMSSDLE 523
+SSSTPE CEE SEKPKKKKKQKPQEVPQE EDPSISFSKPKKKKSFSKEELMSSDLE
Sbjct: 37 DSSSTPERCEETSEKPKKKKKQKPQEVPQEK-TEDPSISFSKPKKKKSFSKEELMSSDLE 95
Query: 524 ETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGSKKKRKFSKEEPVSSGPEEAVGKSSSKK 583
ETAGSTS+ KRKKS+PK ETVNDPEEAG+RS SKKK KFSKEEPVSSGPEEA G SS K
Sbjct: 96 ETAGSTSLLKRKKSSPKTETVNDPEEAGNRSVSKKKTKFSKEEPVSSGPEEAAGSKSSSK 155
Query: 584 KKKFHKASQED 594
KK FHK +QED
Sbjct: 156 KKMFHKEAQED 166
Score = 32.3 bits (72), Expect = 1.3
Identities = 33/117 (28%), Positives = 52/117 (44%), Gaps = 11/117 (9%)
Query: 409 ETGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKKRLKKE------KKRLAALALASS 462
ET E P+K + + Q + I+ K++K K+E ++ + +L
Sbjct: 47 ETSEKPKKKKKQKPQEVPQEKTEDPSISFSKPKKKKSFSKEELMSSDLEETAGSTSLLKR 106
Query: 463 ENSS---STPEECEEMSEKPKKKKKQK-PQEVPQENGMEDPSISFSKPKKKKSFSKE 515
+ SS T + EE + KKK K +E P +G E+ + S S KKK F KE
Sbjct: 107 KKSSPKTETVNDPEEAGNRSVSKKKTKFSKEEPVSSGPEEAAGSKSS-SKKKMFHKE 162
>gi|221136939 pre-mRNA processing factor 31 homolog [Homo sapiens]
Length = 499
Score = 122 bits (307), Expect = 7e-28
Identities = 74/304 (24%), Positives = 152/304 (50%), Gaps = 13/304 (4%)
Query: 167 MIIQSISLLDQLDKDINTFSMRVREWYGYHFPELVKIINDNATYCRLAQFIGNRRELNED 226
+I+ + +L +++ ++N +R+ Y FPEL ++ + Y R + +GN + ++
Sbjct: 92 VIVDANNLTVEIENELNIIHKFIRDKYSKRFPELESLVPNALDYIRTVKELGNSLDKCKN 151
Query: 227 KLEKLEELTMDGAKAKAILDASRSSMGMDISAIDLINIESFSSRVVSLSEYRQSLHTYLR 286
E L+++ + A + + ++ G +S +L +E + L+ + ++ Y+
Sbjct: 152 N-ENLQQI-LTNATIMVVSVTASTTQGQQLSEEELERLEEACDMALELNASKHRIYEYVE 209
Query: 287 SKMSQVAPSLSALIGEAVGARLIAHAGSLTNLAKYPASTVQILGAEKALFRALKTRGNTP 346
S+MS +AP+LS +IG + A+++ AG LTNL+K PA + +LGA++ + P
Sbjct: 210 SRMSFIAPNLSIIIGASTAAKIMGVAGGLTNLSKMPACNIMLLGAQRKTLSGFSSTSVLP 269
Query: 347 KYGLIFHSTFIGRAAAKNKGRISRYLANKCSIASRIDCFSEVPTSVFGEKLREQVEERLS 406
G I+HS + + + +R +A KC++A+R+D F E G +L++++E +
Sbjct: 270 HTGYIYHSDIVQSLPPDLRRKAARLVAAKCTLAARVDSFHESTEGKVGYELKDEIERKFD 329
Query: 407 FYETGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRLAALALASSENSS 466
++ E P + Q + A + + +K+ +R +K K+RL + N
Sbjct: 330 KWQ--EPP---------PVKQVKPLPAPLDGQRKKRGGRRYRKMKERLGLTEIRKQANRM 378
Query: 467 STPE 470
S E
Sbjct: 379 SFGE 382
>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
Length = 248
Score = 65.1 bits (157), Expect = 2e-10
Identities = 60/202 (29%), Positives = 103/202 (50%), Gaps = 21/202 (10%)
Query: 394 GEKLREQVEERLSFYETGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKR 453
G K + EE+++ E +K L+ +E ++ E+++ K +++KKR KK +
Sbjct: 54 GSKALAEFEEKMN-----ENWKKELEKSREKLLSGNESSS----KKRERKKKRKKKSCRS 104
Query: 454 LAALALASSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGMEDPSISFSKPKKKKSFS 513
++ + + S +SSS E+ E+ K +KKKK + + Q + E S S KKKK S
Sbjct: 105 SSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKK-S 163
Query: 514 KEELMSSDLEETAGSTSIPKRKKSTPKEETVN--DPEEAGHRSGSKKKRKFSKEEPVSSG 571
K+E ++ E+ S S KRKKS P ++ ++ E+ + + K+K EE
Sbjct: 164 KDE---TEKEKDVRSLS-KKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEE----- 214
Query: 572 PEEAVGKSSSKKKKKFHKASQE 593
E+A K KKKK+ K S++
Sbjct: 215 REQAKEKVKKKKKKQHKKHSKK 236
Score = 56.2 bits (134), Expect = 8e-08
Identities = 53/209 (25%), Positives = 93/209 (44%), Gaps = 24/209 (11%)
Query: 368 ISRYLANKCSIASRIDCFSEVPTSVFGEKLREQVEERLSFYETGEIPRKNLDVMKEAMVQ 427
+ + L NK + + + F E + ++L + E+ LS E+ R+ K+ +
Sbjct: 44 VKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCR 103
Query: 428 AEEAAAEI--------TRKLEKQEKKRLKKEKKRLAALALASSENSSSTPEECEEMSEKP 479
+ +++ + EK++ KR KK+K R S ++S S+ E E S++
Sbjct: 104 SSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNR-------SYKSSQSSTHESESESKES 156
Query: 480 KKKKKQKPQEVPQENGMEDPSISFSKPKKK-----KSFSKEELMSSDLEETAGSTSIPKR 534
KKKK+ E +E + S SK +KK K S E SD EE + +
Sbjct: 157 VKKKKKSKDETEKEKDVR----SLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRC 212
Query: 535 KKSTPKEETVNDPEEAGHRSGSKKKRKFS 563
++ +E V ++ H+ SKKK+K S
Sbjct: 213 EEREQAKEKVKKKKKKQHKKHSKKKKKKS 241
Score = 40.8 bits (94), Expect = 0.004
Identities = 39/152 (25%), Positives = 63/152 (41%), Gaps = 23/152 (15%)
Query: 443 EKKRLKKEKKRLAALALASSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGMEDPSIS 502
E+ + + E K+ + ALA E E+M+E KK+ ++ +++ N
Sbjct: 42 EEVKKQLENKKTGSKALAEFE---------EKMNENWKKELEKSREKLLSGNESSSKKRE 92
Query: 503 FSKPKKKKSFSKEELMSSDLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGSKKKRKF 562
K +KKKS SS ++ S S + KK G R KK R +
Sbjct: 93 RKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQ-------------GKRRKKKKNRSY 139
Query: 563 SKEEPVSSGPEEAVGKSSSKKKKKFHKASQED 594
K S+ E+ K S KKKKK ++++
Sbjct: 140 -KSSQSSTHESESESKESVKKKKKSKDETEKE 170
>gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]
Length = 237
Score = 59.3 bits (142), Expect = 1e-08
Identities = 53/212 (25%), Positives = 103/212 (48%), Gaps = 20/212 (9%)
Query: 395 EKLREQVEER------LSFYET--GEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKKR 446
E+++EQ+E++ L+ +E E +K L+ +E ++ E++++ ++Q KK+
Sbjct: 32 EEVKEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSK-----KRQRKKK 86
Query: 447 LKKEKKRLAALALASSENSS-STPEECEEMSEKPKKKKKQKPQEVPQENGMEDPSISFSK 505
KK+ R ++ + +SS++SS S+ E E+ + ++KKK+ E+ M +
Sbjct: 87 EKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKD 146
Query: 506 PKKKKSFSKEELMSSDLEETAGSTSIPKRKKSTPK---EETVNDPEEAGHRSGSKKKRKF 562
KKK SK+ ++ E+ S ++ S K E++++ E KKK
Sbjct: 147 SLKKKKKSKD---GTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSE 203
Query: 563 SKEEPVSSGPEEAVGKSSSKKKKKFHKASQED 594
+E+ ++ K SKKKKK +S D
Sbjct: 204 EREKATEKTKKKKKHKKHSKKKKKKAASSSPD 235
Score = 56.2 bits (134), Expect = 8e-08
Identities = 50/188 (26%), Positives = 88/188 (46%), Gaps = 30/188 (15%)
Query: 414 PRKNLDVMKEAM---VQAEEAAAEITRKLEKQEKKRLKKEKKRLAALALASSENSSSTPE 470
PR + +KE + + +A AE K+ + KK L+K +++L L+ SE+SS
Sbjct: 27 PRPTWEEVKEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKL----LSGSESSS---- 78
Query: 471 ECEEMSEKPKKKKKQKPQEVPQENGMEDPSISFS----------KPKKKKSFSKEELMSS 520
+ ++ KK+KK+ + + D S S S K +KKK + S
Sbjct: 79 ---KKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSES 135
Query: 521 DLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGSKKKRKFSKEEPVSS---GPEEAVG 577
+ ET + +KK K+ T + + G SKK++ +S+++P+SS E +
Sbjct: 136 SMSETESDSKDSLKKKKKSKDGTEKEKDIKGL---SKKRKMYSEDKPLSSESLSESEYIE 192
Query: 578 KSSSKKKK 585
+ +KKKK
Sbjct: 193 EVRAKKKK 200
Score = 33.5 bits (75), Expect = 0.57
Identities = 33/127 (25%), Positives = 52/127 (40%), Gaps = 23/127 (18%)
Query: 440 EKQEKKRLKKEKKRLAALALASSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGM--- 496
+K++ KR KK+K R + SSE+S S E + S K KKK K ++ G+
Sbjct: 115 DKKQGKRRKKKKNR----SHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKDIKGLSKK 170
Query: 497 -----EDPSISFS-----------KPKKKKSFSKEELMSSDLEETAGSTSIPKRKKSTPK 540
ED +S + KKKKS + E + ++ K+KK
Sbjct: 171 RKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEEREKATEKTKKKKKHKKHSKKKKKKAA 230
Query: 541 EETVNDP 547
+ + P
Sbjct: 231 SSSPDSP 237
>gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]
Length = 247
Score = 59.3 bits (142), Expect = 1e-08
Identities = 53/212 (25%), Positives = 103/212 (48%), Gaps = 20/212 (9%)
Query: 395 EKLREQVEER------LSFYET--GEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKKR 446
E+++EQ+E++ L+ +E E +K L+ +E ++ E++++ ++Q KK+
Sbjct: 42 EEVKEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSK-----KRQRKKK 96
Query: 447 LKKEKKRLAALALASSENSS-STPEECEEMSEKPKKKKKQKPQEVPQENGMEDPSISFSK 505
KK+ R ++ + +SS++SS S+ E E+ + ++KKK+ E+ M +
Sbjct: 97 EKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKD 156
Query: 506 PKKKKSFSKEELMSSDLEETAGSTSIPKRKKSTPK---EETVNDPEEAGHRSGSKKKRKF 562
KKK SK+ ++ E+ S ++ S K E++++ E KKK
Sbjct: 157 SLKKKKKSKD---GTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSE 213
Query: 563 SKEEPVSSGPEEAVGKSSSKKKKKFHKASQED 594
+E+ ++ K SKKKKK +S D
Sbjct: 214 EREKATEKTKKKKKHKKHSKKKKKKAASSSPD 245
Score = 56.2 bits (134), Expect = 8e-08
Identities = 50/188 (26%), Positives = 88/188 (46%), Gaps = 30/188 (15%)
Query: 414 PRKNLDVMKEAM---VQAEEAAAEITRKLEKQEKKRLKKEKKRLAALALASSENSSSTPE 470
PR + +KE + + +A AE K+ + KK L+K +++L L+ SE+SS
Sbjct: 37 PRPTWEEVKEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKL----LSGSESSS---- 88
Query: 471 ECEEMSEKPKKKKKQKPQEVPQENGMEDPSISFS----------KPKKKKSFSKEELMSS 520
+ ++ KK+KK+ + + D S S S K +KKK + S
Sbjct: 89 ---KKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSES 145
Query: 521 DLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGSKKKRKFSKEEPVSS---GPEEAVG 577
+ ET + +KK K+ T + + G SKK++ +S+++P+SS E +
Sbjct: 146 SMSETESDSKDSLKKKKKSKDGTEKEKDIKGL---SKKRKMYSEDKPLSSESLSESEYIE 202
Query: 578 KSSSKKKK 585
+ +KKKK
Sbjct: 203 EVRAKKKK 210
Score = 33.5 bits (75), Expect = 0.57
Identities = 33/127 (25%), Positives = 52/127 (40%), Gaps = 23/127 (18%)
Query: 440 EKQEKKRLKKEKKRLAALALASSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGM--- 496
+K++ KR KK+K R + SSE+S S E + S K KKK K ++ G+
Sbjct: 125 DKKQGKRRKKKKNR----SHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKDIKGLSKK 180
Query: 497 -----EDPSISFS-----------KPKKKKSFSKEELMSSDLEETAGSTSIPKRKKSTPK 540
ED +S + KKKKS + E + ++ K+KK
Sbjct: 181 RKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEEREKATEKTKKKKKHKKHSKKKKKKAA 240
Query: 541 EETVNDP 547
+ + P
Sbjct: 241 SSSPDSP 247
>gi|12711674 UPF3 regulator of nonsense transcripts homolog B
isoform 2 [Homo sapiens]
Length = 470
Score = 57.0 bits (136), Expect = 5e-08
Identities = 41/178 (23%), Positives = 86/178 (48%), Gaps = 12/178 (6%)
Query: 416 KNLDVMKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRLAALALASSENSSSTPEECEEM 475
KN M+E + E EI RK +++E++R KE+++ + + PE +++
Sbjct: 205 KNKQRMREEK-REERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPER-DKL 262
Query: 476 SEKPKKKKKQKPQEVPQENGMEDPSISFSKPKKKKSFSKEELMSSDLEETAGSTSIPKRK 535
++PK K +KP++ ++ K +K K KE L SD + S ++PKR
Sbjct: 263 KDEPKIKLLKKPEKGDEKE--------LDKREKAKKLDKENL--SDERASGQSCTLPKRS 312
Query: 536 KSTPKEETVNDPEEAGHRSGSKKKRKFSKEEPVSSGPEEAVGKSSSKKKKKFHKASQE 593
S K+E PE+ R +++R++ +++ E + + +++++ + +E
Sbjct: 313 DSELKDEKPKRPEDESGRDYREREREYERDQERILRERERLKRQEEERRRQKERYEKE 370
Score = 43.5 bits (101), Expect = 5e-04
Identities = 44/201 (21%), Positives = 90/201 (44%), Gaps = 23/201 (11%)
Query: 395 EKLREQVEERLSFYETGEIPRKNLDVMK------EAMVQAEEAAAEITRKLEKQEKKRL- 447
E+ R++ EER + E + RK+++ +K E +E ++ +K EK ++K L
Sbjct: 224 ERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELD 283
Query: 448 KKEKKRLAALALASSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGME--DPSISFSK 505
K+EK + S E +S + C + K +KP+ E+G + + + +
Sbjct: 284 KREKAKKLDKENLSDERASG--QSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYER 341
Query: 506 PKKKKSFSKEELMSSDLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGSKKKRKFSKE 565
+++ +E L + E ++K+ KE+T EE KK++ ++
Sbjct: 342 DQERILRERERLKRQEEERR-------RQKERYEKEKTFKRKEEE-----MKKEKDTLRD 389
Query: 566 EPVSSGPEEAVGKSSSKKKKK 586
+ + E++G S +KK+
Sbjct: 390 KGKKAESTESIGSSEKTEKKE 410
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 55.1 bits (131), Expect = 2e-07
Identities = 43/204 (21%), Positives = 88/204 (43%), Gaps = 6/204 (2%)
Query: 389 PTSVFGEKLREQVEERLSFYETGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKKRLK 448
P F EK + V+E + E + P K E + +E ++ EK ++ ++K
Sbjct: 777 PADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVK 836
Query: 449 K-----EKKRLAALALASSENSSSTPEECEEMSEKPKKKKKQKPQ-EVPQENGMEDPSIS 502
+ E+++ A + S E ++ + KPK ++K++P E P+E+ +E
Sbjct: 837 EPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEE 896
Query: 503 FSKPKKKKSFSKEELMSSDLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGSKKKRKF 562
KK + KE +++E A + K P + +P + + + ++K
Sbjct: 897 AEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKD 956
Query: 563 SKEEPVSSGPEEAVGKSSSKKKKK 586
+KEE E+ ++ +K+ K
Sbjct: 957 TKEEKAKKPEEKPKTEAKAKEDDK 980
Score = 52.0 bits (123), Expect = 2e-06
Identities = 57/213 (26%), Positives = 87/213 (40%), Gaps = 23/213 (10%)
Query: 386 SEVPTSVFGEKLREQVEERLSFYETGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKK 445
++V V E+ +E EE E GE + AEEAA+ EK+ K
Sbjct: 464 TQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASP-----EKEAKS 518
Query: 446 RLKKEKKRLAALALASSENSSSTPE-ECEEMSEKPKKKKKQKPQEV--PQENGMEDPSIS 502
+K+E K A E + S E + E ++ P K++ + P E P++ + P+
Sbjct: 519 PVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPA-E 577
Query: 503 FSKPKKKKSFSKEELMS-----------SDLEETAGSTSIPKRKKSTPKEETVNDPEEAG 551
P+K KS +KEE S S ++E A S P KS KEE + E
Sbjct: 578 VKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKS---PAEAKSPVKEEAKSPAEVKS 634
Query: 552 HRSGSKKKRKFSKEEPVSSGPEEAVGKSSSKKK 584
++ +K + PE+ KS K K
Sbjct: 635 PEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAK 667
Score = 47.8 bits (112), Expect = 3e-05
Identities = 54/216 (25%), Positives = 93/216 (43%), Gaps = 24/216 (11%)
Query: 397 LREQVEERLSFYETGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRLAA 456
++ + EE++ E E V+ E + + E+T + EK+ K+ KE++
Sbjct: 436 IKVKSEEKIKVVEKSE----KETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEE 491
Query: 457 LALASSENSSSTP--EEC---EEMSEKPKKKKKQKPQEV--PQENGMEDPSISFSKPKKK 509
E + +P EE E+ ++ P K++ + P E P++ + P+ P+K
Sbjct: 492 EEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPA-EVKSPEKA 550
Query: 510 KSFSKE------ELMSSDLEETAGSTSI--PKRKKSTPKEETVNDPEEAGHRSGSK---K 558
KS +KE E S + EE + P++ KS KEE P EA +K K
Sbjct: 551 KSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEE-AKSPAEAKSPEKAKSPVK 609
Query: 559 KRKFSKEEPVSSGPEEAVGKSSSKKKKKFHKASQED 594
+ S E S EEA + K +K ++E+
Sbjct: 610 EEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEE 645
Score = 47.4 bits (111), Expect = 4e-05
Identities = 51/196 (26%), Positives = 83/196 (42%), Gaps = 25/196 (12%)
Query: 414 PRKNLDVMKEAMVQAEEAAAEITRKLEKQEKKR--LKKEKKRLAALALASSENSSSTPEE 471
P K +KE E+A + + + + EK + +K+E K + E + S +E
Sbjct: 691 PEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAK--------TPEKAKSPVKE 742
Query: 472 CEEMSEKPKKKKKQKPQEV-------PQENGMEDPSISFSKPKKKKSFSKEELMSSDLEE 524
+ EK K +K K +V P + P+ F P+K KS KEE+ S + +
Sbjct: 743 EAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKF--PEKAKSPVKEEVKSPEKAK 800
Query: 525 TAGSTSIPKRKKSTPKEETVNDP---EEAGHRSGSKKKRKFSKEEPVSSGPEEAVGKSSS 581
+ +K PK+E V P EE K+ K ++EE + P+ K S
Sbjct: 801 SPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSK 860
Query: 582 KK---KKKFHKASQED 594
K+ KK+ K E+
Sbjct: 861 KEEAPKKEAPKPKVEE 876
Score = 47.0 bits (110), Expect = 5e-05
Identities = 52/200 (26%), Positives = 84/200 (42%), Gaps = 19/200 (9%)
Query: 409 ETGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRLAALALASSENSSST 468
E + P K +KE E+A + + + + EK + ++ K L + S E +
Sbjct: 714 EEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAK---TLDVKSPEAKTPA 770
Query: 469 PEECEEMSEK-PKKKKKQKPQEVPQENGMEDPSISFSKPKKKKSFSKEELMSSDLEETAG 527
EE ++K P+K K +EV + P +K +K+ KEE+ S EE
Sbjct: 771 KEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKP 830
Query: 528 S----TSIPKRKK-----STPKEETVND--PEEAGHRSGSKKKRKFSKEEPVSSGPEEA- 575
PK+ + +TPK E D EEA + K K + K+EP P+E+
Sbjct: 831 QEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVE-EKKEPAVEKPKESK 889
Query: 576 --VGKSSSKKKKKFHKASQE 593
K ++ KKK +E
Sbjct: 890 VEAKKEEAEDKKKVPTPEKE 909
Score = 45.1 bits (105), Expect = 2e-04
Identities = 46/197 (23%), Positives = 84/197 (42%), Gaps = 14/197 (7%)
Query: 402 EERLSFYETGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRLAALALAS 461
EE+ + E P+K + A + EE + K+E + K E+K+ A+
Sbjct: 827 EEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPK 886
Query: 462 SENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGMEDPSISFSKPKKKKSFSKEE---LM 518
+ EE E+ KKK +E P + +++ +KPK+K +K+E
Sbjct: 887 ESKVEAKKEEAED-----KKKVPTPEKEAPAKVEVKED----AKPKEKTEVAKKEPDDAK 937
Query: 519 SSDLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGSKKKRKFSKEEPVSSGPEEAVGK 578
+ + + A KK T +E+ E+ + +K+ K +EP E+A
Sbjct: 938 AKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKS 997
Query: 579 SSSKKK--KKFHKASQE 593
SS+ +K K KA+++
Sbjct: 998 SSTDQKDSKPPEKATED 1014
Score = 42.4 bits (98), Expect = 0.001
Identities = 38/189 (20%), Positives = 77/189 (40%), Gaps = 20/189 (10%)
Query: 396 KLREQVEERLSFYETGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRLA 455
K E+ + + E P+ ++ KE V+ + + +K E ++KK++ +K
Sbjct: 852 KTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEK--- 908
Query: 456 ALALASSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGMEDPSISFSKPKKKKSFSKE 515
P + E + K+K + ++ P + ++P SKP +KK + E
Sbjct: 909 -----------EAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEP----SKPAEKKEAAPE 953
Query: 516 ELMSSDLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGSKKKRKFSKEEPVSSGPEEA 575
+ EE A + ++ KE+ +E K ++ S ++ S PE+A
Sbjct: 954 K--KDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKA 1011
Query: 576 VGKSSSKKK 584
++K K
Sbjct: 1012 TEDKAAKGK 1020
Score = 42.0 bits (97), Expect = 0.002
Identities = 54/218 (24%), Positives = 89/218 (40%), Gaps = 27/218 (12%)
Query: 395 EKLREQVEERLSFYETGEIPRKNLDVMKE---AMVQAEEAAAEITRKLEKQEKKRLKKEK 451
EK + +E E + P K E + V+AE + E + K E K +K K
Sbjct: 636 EKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAK 695
Query: 452 KRLAALALASSENSSSTPEECE--EMSEKPKKKKKQKPQEV--PQENGMEDPSISFSKPK 507
+ A + + S EE + E ++ P K++ + P++ P + + P + S K
Sbjct: 696 SPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEK 755
Query: 508 KK---------KSFSKEELMSSDLEETAGSTSIPKRKKSTPKEETVNDPEEAG---HRSG 555
K K+ +KEE S + P++ KS KEE V PE+A
Sbjct: 756 AKTLDVKSPEAKTPAKEEARSP-------ADKFPEKAKSPVKEE-VKSPEKAKSPLKEDA 807
Query: 556 SKKKRKFSKEEPVSSGPEEAVGKSSSKKKKKFHKASQE 593
+++ K+E V S +E K K+ KA +E
Sbjct: 808 KAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEE 845
Score = 41.2 bits (95), Expect = 0.003
Identities = 51/193 (26%), Positives = 82/193 (42%), Gaps = 15/193 (7%)
Query: 402 EERLSFYETGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKKRLK------KEKKRLA 455
EE S E + +EA AE + E + K+E K KE+ +
Sbjct: 570 EEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSP 629
Query: 456 ALALASSENSSSTPEECE--EMSEKPKKKKKQKPQEVPQENGMEDPSISFSKPKKKKSFS 513
A + + S T EE + E ++ P+K++ + P++ E S +K K
Sbjct: 630 AEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAK 689
Query: 514 KEELMSSDLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGSKKKRKFSKEEPVSSGPE 573
E S ++E A S P++ KS KEE PE+A +S K++ K + E+ S E
Sbjct: 690 SPEKAKSPVKEEAKS---PEKAKSPVKEE-AKSPEKA--KSPVKEEAK-TPEKAKSPVKE 742
Query: 574 EAVGKSSSKKKKK 586
EA +K +K
Sbjct: 743 EAKSPEKAKSPEK 755
Score = 40.4 bits (93), Expect = 0.005
Identities = 40/162 (24%), Positives = 69/162 (42%), Gaps = 4/162 (2%)
Query: 427 QAEEAAAEITRKLEKQEKKRLKKEKKRLAALALASSENSSSTPE-ECEEMSEKPKKKKKQ 485
+ EEA + K ++ K K+E K E + S E + E ++ P K++ +
Sbjct: 534 EKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAK 593
Query: 486 KPQEVPQENGMEDPSISFSK-PKKKKSFSKEELMS-SDLEETAGSTSIPKRKKSTPKEET 543
P E + P +K P + KS KEE S ++++ + S K + +P++
Sbjct: 594 SPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAK 653
Query: 544 VNDPEEAGHRSGSKKKRKFSKEEP-VSSGPEEAVGKSSSKKK 584
+ EEA +K K + P + P +A KS K K
Sbjct: 654 SPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAK 695
>gi|18375528 UPF3 regulator of nonsense transcripts homolog B
isoform 1 [Homo sapiens]
Length = 483
Score = 55.1 bits (131), Expect = 2e-07
Identities = 44/183 (24%), Positives = 88/183 (48%), Gaps = 9/183 (4%)
Query: 416 KNLDVMKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRLAALALASSENSSSTPEECEEM 475
KN M+E + E EI RK +++E++R KE+++ + + PE +++
Sbjct: 205 KNKQRMREEK-REERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPER-DKL 262
Query: 476 SEKPK-KKKKQKPQEVPQENGMEDPSIS----FSKPKKKKSFSKEELMSSDLEETAGSTS 530
++PK K + Q V Q+N ++ P K +K K KE L SD + S +
Sbjct: 263 KDEPKIKVHRFLLQAVNQKNLLKKPEKGDEKELDKREKAKKLDKENL--SDERASGQSCT 320
Query: 531 IPKRKKSTPKEETVNDPEEAGHRSGSKKKRKFSKEEPVSSGPEEAVGKSSSKKKKKFHKA 590
+PKR S K+E PE+ R +++R++ +++ E + + +++++ +
Sbjct: 321 LPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERILRERERLKRQEEERRRQKERY 380
Query: 591 SQE 593
+E
Sbjct: 381 EKE 383
Score = 36.2 bits (82), Expect = 0.087
Identities = 44/215 (20%), Positives = 91/215 (42%), Gaps = 38/215 (17%)
Query: 395 EKLREQVEERLSFYETGEIPRKNLDVMKEA--------------------MVQAEEAAAE 434
E+ R++ EER + E + RK+++ +K+ ++QA
Sbjct: 224 ERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKVHRFLLQAVNQK-N 282
Query: 435 ITRKLEKQEKKRL-KKEKKRLAALALASSENSSSTPEECEEMSEKPKKKKKQKPQEVPQE 493
+ +K EK ++K L K+EK + S E +S + C + K +KP+ E
Sbjct: 283 LLKKPEKGDEKELDKREKAKKLDKENLSDERASG--QSCTLPKRSDSELKDEKPKRPEDE 340
Query: 494 NGME--DPSISFSKPKKKKSFSKEELMSSDLEETAGSTSIPKRKKSTPKEETVNDPEEAG 551
+G + + + + +++ +E L + E ++K+ KE+T EE
Sbjct: 341 SGRDYREREREYERDQERILRERERLKRQEEERR-------RQKERYEKEKTFKRKEEE- 392
Query: 552 HRSGSKKKRKFSKEEPVSSGPEEAVGKSSSKKKKK 586
KK++ +++ + E++G S +KK+
Sbjct: 393 ----MKKEKDTLRDKGKKAESTESIGSSEKTEKKE 423
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 53.5 bits (127), Expect = 5e-07
Identities = 58/233 (24%), Positives = 96/233 (41%), Gaps = 31/233 (13%)
Query: 375 KCSIASRIDCFSEVPTSVFGE-KLREQVEERLSFYETGEIPRKNLDVMKEAMVQAEEAA- 432
K +A++ D +VPT V + KL+++ + R S + P + V KE+ + E
Sbjct: 512 KQPLATQKDLTGQVPTPVVKQTKLKQRADSRESLKPAAK-PLPSKSVRKESKEETPEVTK 570
Query: 433 ---AEITRKLEKQEKKRLKKEKK-------RLAALALASSENSSSTPEECEEMSEKPKKK 482
E K+E +EK +KK+K + + S E S E E K
Sbjct: 571 VNHVEKPPKVESKEKVMVKKDKPIKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKP 630
Query: 483 KKQKPQEVPQENGMEDPSISFSKPKKKKSFSKEELMSSDLEETAGSTSIPKRKKSTPKEE 542
K K + V +E ++ K K KK +K+E P +K+ PK+E
Sbjct: 631 KAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKE------------DKTPIKKEEKPKKE 678
Query: 543 TVNDPEEAGHRSGSKK--KRKFSKEEPVSSGPEEAVGKSSSKKKKKFHKASQE 593
V + + KK K++ KE P P+E + ++KK+ K +E
Sbjct: 679 EVKKEVKKEIKKEEKKEPKKEVKKETP----PKEVKKEVKKEEKKEVKKEEKE 727
Score = 49.3 bits (116), Expect = 1e-05
Identities = 50/171 (29%), Positives = 73/171 (42%), Gaps = 12/171 (7%)
Query: 422 KEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRLAALALASSENSSSTPEECEEMSEKPKK 481
K+A +AA E T K E + K KKE+K +A E+ TP + EE +K +
Sbjct: 623 KQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDK--TPIKKEEKPKKEEV 680
Query: 482 KKKQKPQEVPQENGMEDPSISFSKPKK--KKSFSKEELMSSDLEETAGSTSIPK-----R 534
KK+ K + +E + P K KK KEE EE I K +
Sbjct: 681 KKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAK 740
Query: 535 KKSTPKEETVNDPEEAGHRSGSKKKRKFSKEEPVSSGPEEAVGKSSSKKKK 585
K STP E + A + KK + K++ V++G + GK KK+
Sbjct: 741 KSSTPLSEA---KKPAALKPKVPKKEESVKKDSVAAGKPKEKGKIKVIKKE 788
Score = 48.1 bits (113), Expect = 2e-05
Identities = 30/123 (24%), Positives = 58/123 (47%), Gaps = 5/123 (4%)
Query: 420 VMKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRLAALALASSENSSSTPEECEEMSEKP 479
+ KE + EE E+ ++++K+EKK KKE K+ E +E ++ ++P
Sbjct: 669 IKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEP 728
Query: 480 KKKKKQKPQE-----VPQENGMEDPSISFSKPKKKKSFSKEELMSSDLEETAGSTSIPKR 534
KK+ K+ P++ P + ++ PKK++S K+ + + +E I K
Sbjct: 729 KKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDSVAAGKPKEKGKIKVIKKE 788
Query: 535 KKS 537
K+
Sbjct: 789 GKA 791
Score = 31.2 bits (69), Expect = 2.8
Identities = 31/125 (24%), Positives = 54/125 (43%), Gaps = 21/125 (16%)
Query: 439 LEKQEKKRLKKEKKRLAALALASSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGMED 498
+E+ K LKK+ K ++ SS+P + + KP P+ G+++
Sbjct: 2227 IEQNLGKALKKDLKEKTKTKKPGTKTKSSSPVKKSDGKSKPLAAS-------PKPAGLKE 2279
Query: 499 PSISFSK---PKKKKSFSKEELMSSDLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRSG 555
S S+ PKKK+S +E+ A T+ P+ K+ EE + + A + S
Sbjct: 2280 SSDKVSRVASPKKKES----------VEKAAKPTTTPE-VKAARGEEKDKETKNAANASA 2328
Query: 556 SKKKR 560
SK +
Sbjct: 2329 SKSAK 2333
>gi|40068059 CBF1 interacting corepressor [Homo sapiens]
Length = 450
Score = 53.1 bits (126), Expect = 7e-07
Identities = 47/175 (26%), Positives = 75/175 (42%), Gaps = 22/175 (12%)
Query: 434 EITRKLEKQEKKRLKKEKKRL----------------AALALASSENSSSTPEECEEMSE 477
++ RKL++ EKK+ KK++K+ ++ + +SS +S+ T E E
Sbjct: 223 KLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESES 282
Query: 478 KPKKKKKQKPQEVPQENGMEDPSISFSKPKKKKSFSKEELMSSDLEETAGSTSIPKRKKS 537
K+KK Q+ + + + S S K K KK EEL SS K K
Sbjct: 283 NNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKA-----KEKPR 337
Query: 538 TPKEETVNDPEEAGHRSGSKKKRKFSKEEPVSSGPEEAVGKSSSKKKKKFHKASQ 592
K E+ + + H S S KK + K P G E G S S +++ + S+
Sbjct: 338 FLKHESSREDSKWSH-SDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRSR 391
Score = 35.0 bits (79), Expect = 0.19
Identities = 34/130 (26%), Positives = 56/130 (43%), Gaps = 6/130 (4%)
Query: 461 SSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGMEDPSISFSKPKKKKSFSKEELMSS 520
S E +S EE E+ KQK + + + + +E K +KKK F K
Sbjct: 196 SQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKK--KKKKDRKKKKFQKSRSKHK 253
Query: 521 DLEETAGSTSIPKRKKSTPKEETVNDPEEAG-HRSGSKKKRKFSKEEPVSSGPEEAVGKS 579
+ ++ S+S ST E+ ++ E + +KKRK +K ++ E KS
Sbjct: 254 KHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKS 313
Query: 580 SSKKKKKFHK 589
KK+K H+
Sbjct: 314 ---KKRKLHE 320
>gi|190341068 forkhead-associated (FHA) phosphopeptide binding
domain 1 [Homo sapiens]
Length = 1412
Score = 48.9 bits (115), Expect = 1e-05
Identities = 106/544 (19%), Positives = 213/544 (39%), Gaps = 89/544 (16%)
Query: 23 EEISLLQPQVEESVLNLGKFHSIVRLVAFCPFASSQVALENANAVSEGVVHEDLRLLLET 82
EE+S L+ Q N K H + L + C ++ E+A+ ++L+L +T
Sbjct: 368 EEVSHLKSQ------NKDKDHQLEALGSRCSVLKEELKQEDAHRELREAQEKELKLC-KT 420
Query: 83 HLPSKKKKVLLGVGDPKIGAAIQEELGYNCQTGGVIAEILRGVRLHFHNLVKGLTDLSAC 142
+ +K++ ++ EL +C VI+ LR L +
Sbjct: 421 QIQDMEKEM----------KKLRAELRKSCTEQSVISRTLREKSKVEEKLQEDSRRKLLQ 470
Query: 143 KAQLGLGHSYSRAKVKFNVNRVDNMIIQSISLLDQLDKDINTFSMRVREWYGYHFPELVK 202
++G S + ++ V ++++ Q I K + ++ ++ +
Sbjct: 471 LQEMGNRESVIKINLERAVGQLEHFRSQVIKATYGRAKPFRDKPVTDQQL----IEKITQ 526
Query: 203 IINDNATYCRLAQFIGNRRELNEDKLEKLEELTMDGAKAKAILDASRSSMGMDISAIDLI 262
+ DN + + + +L+ K E E T + K + LD+ ++ M + + DL
Sbjct: 527 VTEDNINFQQKKWTLQKETQLSNSKQE---ETTENIEKLRTSLDSCQACMKISCCSHDL- 582
Query: 263 NIESFSSRVVSLSEYRQSLHTYLRSKMSQVAPSLSALIGEAVGARLIAHAGS-------- 314
+ V L ++ Q V+P +S L + V ++ HA S
Sbjct: 583 ------KKEVDLLQHLQ------------VSPPVSGL--QKVVLDVLRHALSWLEEVEQL 622
Query: 315 LTNLAKYPAST----VQILGAEKALFRALKTRGNTPKYGLIFHSTFIGRAAAKNKGRISR 370
L +L P+S VQ A+F A K G + + G R A+++ + +
Sbjct: 623 LRDLGILPSSPNKDQVQQFSGNSAVFTAGKAAGASGREGEAERGEARARGEAQSQNQATD 682
Query: 371 YLANKCSIASRIDCFSEVPTSVFGEKLREQV-EERLSFYETGEIPRKNLDVMKEAMVQAE 429
G+ L E + +ER ET E RK + ++ + Q +
Sbjct: 683 GREG-------------------GKALEEYITQERNRAKETLEEERKRMQELESLLAQQK 723
Query: 430 EAAAE-ITRKLEK------QEKKRLKKEKKRLAALALASSENSSSTPEECEEMSEKPKKK 482
+A A+ IT++ + +E+ R+++ ++RLA + + + +E E K+K
Sbjct: 724 KALAKSITQEKNRVKEALEEEQTRVQELEERLARQKEVLESSIAHEKRKAKEALESEKRK 783
Query: 483 KKQKPQEVPQENGMEDPSISFSKPKKKKSFSKEELMSSDLEETAGSTSIPKRKKSTPKEE 542
+ + Q+ + + +I++ K K K++ KE+ DLE + K+K+ +E
Sbjct: 784 VQDLENHLTQQKEISESNIAYEKRKAKEAMEKEKKKVQDLE-----NRLTKQKEELELKE 838
Query: 543 TVND 546
D
Sbjct: 839 QKED 842
>gi|157738619 smoothelin-like 1 [Homo sapiens]
Length = 512
Score = 48.9 bits (115), Expect = 1e-05
Identities = 50/214 (23%), Positives = 99/214 (46%), Gaps = 24/214 (11%)
Query: 386 SEVPTSVFGEKLREQVEERLSFYETGEIPRKNLDVMK-EAMVQA---EEAAAEITRKLEK 441
+E P + G++ + E+ +S GE LD +K E+ +A E+A AE+ ++ +
Sbjct: 61 NEGPPTESGKQEKAPAEDGMSAELQGEA--NGLDEVKVESQREAGGKEDAEAELKKEDGE 118
Query: 442 QEKKRLKKEKKRLAALALASSENSSSTPEECEEM-SEKPKKKKKQKPQEVPQENGMEDPS 500
+E+ + ++ E + S P+E EE S +K+K + +E E+G + +
Sbjct: 119 KEETTVGSQEMT------GRKEETKSEPKEAEEKESTLASEKQKAEEKEAKPESGQKADA 172
Query: 501 ISFSKPKKKKSFSKEELMSSDLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGSKKKR 560
KP+ K + +E+ ++ EET K + PKE+ ++ +A + +
Sbjct: 173 NDRDKPEPKATVEEEDAKTASQEETGQR----KECSTEPKEKATDEEAKA-------ESQ 221
Query: 561 KFSKEEPVSSGPEEAVGKSSSKKKKKFHKASQED 594
K E+ + P+E GK +K K ++E+
Sbjct: 222 KAVVEDEAKAEPKEPDGKEEAKHGAKEEADAKEE 255
>gi|118498359 ribosomal L1 domain containing 1 [Homo sapiens]
Length = 490
Score = 48.5 bits (114), Expect = 2e-05
Identities = 38/159 (23%), Positives = 74/159 (46%), Gaps = 13/159 (8%)
Query: 437 RKLEKQEKKRLKKEKKRLAALALASSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGM 496
R EKQ++++ K+++ R A L+ + + PE + +KP+ KK+Q P+ ++ G
Sbjct: 294 RNFEKQKERKKKRQQARKTASVLSKDDVA---PESGDTTVKKPESKKEQTPEHGKKKRGR 350
Query: 497 EDPSISFSKPKKKKSFSKEEL--MSSDLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRS 554
+ K + S++E+ + ++T + + +K +T K+ P + R
Sbjct: 351 GKAQV------KATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPR- 403
Query: 555 GSKKKRKFSKEEPVSSGPEEAVGKSSSKKKKKFHKASQE 593
KK++ E + E GKS KK K +A +E
Sbjct: 404 -GKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKE 441
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 48.1 bits (113), Expect = 2e-05
Identities = 39/203 (19%), Positives = 93/203 (45%), Gaps = 13/203 (6%)
Query: 395 EKLREQVEERLSFYETGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRL 454
E++R+Q E+ E + + + +E M + EE E ++ +QE++ LK++++
Sbjct: 227 EQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQ-- 284
Query: 455 AALALASSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGMEDPSISFSKPKKKKSFSK 514
+E T E+ E+M E+ ++ ++Q+ Q QE M + K +++ K
Sbjct: 285 -------TEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQK 337
Query: 515 EELMSSDLEETAGSTSIPKRKKSTPK-EETVNDPEEAGHRSGS---KKKRKFSKEEPVSS 570
E++ + + ++++ K EE V EE + K++ + K+E
Sbjct: 338 EQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMG 397
Query: 571 GPEEAVGKSSSKKKKKFHKASQE 593
+E +G+ + +++ + ++
Sbjct: 398 EQKEQMGEQKEQMREQEEQMGEQ 420
Score = 40.4 bits (93), Expect = 0.005
Identities = 37/172 (21%), Positives = 77/172 (44%), Gaps = 10/172 (5%)
Query: 395 EKLREQVEERLSFYETGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRL 454
E++REQ EE++ E + +K +E + EE E ++ +QE++ ++++++++
Sbjct: 262 EQMREQ-EEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQ-MREQEEQM 319
Query: 455 AALALASSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGMEDPSISFSKP-----KKK 509
+ E+ E+M E+ ++ KQ+ Q QE M+ K K++
Sbjct: 320 REQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQE 379
Query: 510 KSFSKEELMSSDLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGSKKKRK 561
+ K+E EE G K + KE+ E+ G + +K++
Sbjct: 380 EQMRKQEEQMRKQEEQMGE---QKEQMGEQKEQMREQEEQMGEQKEQMRKQE 428
Score = 38.9 bits (89), Expect = 0.013
Identities = 26/164 (15%), Positives = 71/164 (43%), Gaps = 3/164 (1%)
Query: 422 KEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRLAALALASSENSSSTPEECEEMSEKPKK 481
+E V+ +E ++++ ++ +++ ++ E ++ E+M E+ ++
Sbjct: 169 QEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQ 228
Query: 482 KKKQKPQEVPQENGMEDPSISFSKPKKKKSFSKEELMSSDLEETAGSTSIPKRKKSTPKE 541
+KQ+ Q QE ++ K +++ +E++ + + + K+K+ T +E
Sbjct: 229 MRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQE 288
Query: 542 ETVNDPEEAGHRSGS---KKKRKFSKEEPVSSGPEEAVGKSSSK 582
E + EE +++ + ++E EE +GK +
Sbjct: 289 EQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQ 332
Score = 38.9 bits (89), Expect = 0.013
Identities = 37/202 (18%), Positives = 90/202 (44%), Gaps = 6/202 (2%)
Query: 396 KLREQVEERLSFYETGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRLA 455
++ EQ E+ E + + + +E M + EE E +++KQE++ ++K+++++
Sbjct: 200 QMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQ-VQKQEEQMR 258
Query: 456 ALALASSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGMEDPSISFSKPKKKKSFSKE 515
E E+ EE K K++ +Q+ Q QE M + + +++ +E
Sbjct: 259 KQEEQMREQEEQMREQ-EEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEE 317
Query: 516 ELMSSDLEETAGSTSIPKRKKS--TPKEETVNDPEEAGHRSG--SKKKRKFSKEEPVSSG 571
++ + + + ++K+ KE+ E+ G + K++ + K+E
Sbjct: 318 QMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRK 377
Query: 572 PEEAVGKSSSKKKKKFHKASQE 593
EE + K + +K+ + ++
Sbjct: 378 QEEQMRKQEEQMRKQEEQMGEQ 399
Score = 37.7 bits (86), Expect = 0.030
Identities = 30/121 (24%), Positives = 55/121 (45%), Gaps = 1/121 (0%)
Query: 395 EKLREQVEERLSFYETGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRL 454
E++REQ E+ E ++ + KE M + EE E +++KQE++ K+E++
Sbjct: 317 EQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMR 376
Query: 455 AALALASSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGMEDPSISFSKPKKKKSFSK 514
+ +E E+M E+ ++ +QK Q QE M + K ++ K
Sbjct: 377 KQEEQMRKQEEQMRKQE-EQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQK 435
Query: 515 E 515
E
Sbjct: 436 E 436
Score = 29.6 bits (65), Expect = 8.2
Identities = 23/129 (17%), Positives = 59/129 (45%), Gaps = 6/129 (4%)
Query: 395 EKLREQVEERLSFYETGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKK------RLK 448
E++REQ E+ E + + +E M + +E E ++ KQE++ +++
Sbjct: 303 EQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQ 362
Query: 449 KEKKRLAALALASSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGMEDPSISFSKPKK 508
K+++++ + ++ E+M ++ ++ +QK Q Q+ M + + K+
Sbjct: 363 KQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKE 422
Query: 509 KKSFSKEEL 517
+ +E +
Sbjct: 423 QMRKQEEHM 431
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 48.1 bits (113), Expect = 2e-05
Identities = 46/196 (23%), Positives = 88/196 (44%), Gaps = 11/196 (5%)
Query: 409 ETGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKKR-LKKEKKRLAALALASSENSSS 467
+T + +K+ D E A++ + ++ + ++K +KK+ +KK+ + A + S +
Sbjct: 287 DTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKD 346
Query: 468 TPEECEEMSEKPKKKKKQK-PQEVPQENG----MEDPSISFSKPKK---KKSFSKEELMS 519
T ++ +++ + KKK +K P+ E+G + S + K K KK +K+ S
Sbjct: 347 TKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFS 406
Query: 520 SDLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGSKKKRKFSKEEPVSSGPEEAVGKS 579
+D E S K +K K+ ++ + + S K + +E GK
Sbjct: 407 TDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKK 466
Query: 580 SSKK--KKKFHKASQE 593
SKK KKK K + E
Sbjct: 467 DSKKDDKKKDAKKNAE 482
Score = 40.4 bits (93), Expect = 0.005
Identities = 41/154 (26%), Positives = 70/154 (45%), Gaps = 7/154 (4%)
Query: 445 KRLKKEKKRLAALALASSENSSSTPEECEEMSEKPKK--KKKQKPQEVPQENGMEDPSIS 502
K KK+ K+ A SS+ S ++ ++ S+K KK KK K ++V ++ D
Sbjct: 282 KYTKKDTKKNAK---KSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESG 338
Query: 503 FSKPKKKKS-FSKEELMSSDLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGSKKKRK 561
SK ++K + K++L D ++ +S ++ ND S + K+K
Sbjct: 339 DSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKK 398
Query: 562 FSKEEPVSSGPE-EAVGKSSSKKKKKFHKASQED 594
+K+ S+ E E K S K +KK K S+ D
Sbjct: 399 DAKKITFSTDSESELESKESQKDEKKDKKDSKTD 432
Score = 35.8 bits (81), Expect = 0.11
Identities = 42/160 (26%), Positives = 69/160 (43%), Gaps = 26/160 (16%)
Query: 437 RKLEKQEKKRLKKEKKRLAALALASSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGM 496
+K EK+ KK KK+ K+ A +N+ ST E + +K KK K+K
Sbjct: 458 KKDEKKGKKDSKKDDKKKDA-----KKNAESTEMESDLELKKDKKHSKEKK--------- 503
Query: 497 EDPSISFSKPKKKKSFSKEELMSSDLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGS 556
K K ++++ S+D E S + K ST + + + EE+ ++ G+
Sbjct: 504 -------GSKKDIKKDARKDTESTDAEFDESSKT--GFKTSTKIKGSDTESEESLYKPGA 554
Query: 557 KKKRKFSKEEPVSS---GPEEAVGKSSSKKKKKFHKASQE 593
KKK S +S G E G S KK F++ ++
Sbjct: 555 KKKIDESDGTSANSKMEGLESKRGFRMSSKKTTFNEKGEK 594
Score = 30.0 bits (66), Expect = 6.3
Identities = 36/208 (17%), Positives = 81/208 (38%), Gaps = 18/208 (8%)
Query: 394 GEKLREQVEERLSFYETGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKR 453
G L++ +++ Y T ++ ++ + +A++ + + + E+ +K + E
Sbjct: 124 GTPLKKDSKKKGGSYATNPESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSKSSSETN- 182
Query: 454 LAALALASSENSSSTPEECEEMSEKPKKKKKQKPQEV--PQENGMEDPSISFSKPKKKKS 511
S+NS + + C + +K K K+ E + N +D S +
Sbjct: 183 ------PESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISE 236
Query: 512 FSKEELMSSDLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGSKKKRKFSKEE----- 566
E ++ D G + +S + + + + ++ S K K++K++
Sbjct: 237 ICSENSLNVDFLMLVGQSD----DESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNA 292
Query: 567 PVSSGPEEAVGKSSSKKKKKFHKASQED 594
SS E K + K KK K ++D
Sbjct: 293 KKSSDAESEDSKDAKKDSKKVKKNVKKD 320
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 48.1 bits (113), Expect = 2e-05
Identities = 49/206 (23%), Positives = 95/206 (46%), Gaps = 16/206 (7%)
Query: 395 EKLREQVEERLSFYETGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQ--EKKRLKKEKK 452
E+ R + EE + K L+ K AM + + ++ +K+E + +K+ +++K
Sbjct: 369 ERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKL 428
Query: 453 RLAALALASSENSSSTPEECEEMSE-KPKKKKKQ-KPQEVPQENGMEDPSISFSKPKKKK 510
+ A L E + + E++ E KP KK++ K +++ ++ ++ SF +KK
Sbjct: 429 QTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMD--RKK 486
Query: 511 SFSK-----EELMSSDLEETAGSTSIPKRKKSTPKEETVNDPE-EAGHRSGSKKKRKFSK 564
F++ E M+ L+ T + S P + S +E P+ EAG R ++R+
Sbjct: 487 GFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGET 546
Query: 565 E----EPVSSGPEEAVGKSSSKKKKK 586
E E + +EA + KKK+
Sbjct: 547 ESEEFEKLKQKQQEAALELEELKKKR 572
Score = 45.8 bits (107), Expect = 1e-04
Identities = 44/201 (21%), Positives = 88/201 (43%), Gaps = 15/201 (7%)
Query: 395 EKLREQVEERLSFYETGEIPRKNLDVMKEAMVQAEE-AAAEITRKLEKQEKKRLKKEKKR 453
E+ R + EER E +K D + A ++AEE AAA+ + E +E++R+++E+KR
Sbjct: 268 ERARLEAEERERI--KAEQDKKIAD--ERARIEAEEKAAAQERERREAEERERMREEEKR 323
Query: 454 LAALALASSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGMEDPSISFSKPKKKKSFS 513
A E EE + + E+ K+ +++ + +E + +++K+
Sbjct: 324 AAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKV 383
Query: 514 KEELMSSDLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGSKKKRKFSKEEPVSSGPE 573
+E+ + LEE KK +E + + G K ++E+ + +
Sbjct: 384 EEQKRNKQLEE----------KKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVL 433
Query: 574 EAVGKSSSKKKKKFHKASQED 594
+ G+ K + + QED
Sbjct: 434 KKQGEEKGTKVQAKREKLQED 454
Score = 35.0 bits (79), Expect = 0.19
Identities = 42/155 (27%), Positives = 71/155 (45%), Gaps = 8/155 (5%)
Query: 395 EKLRE-QVEERLSFYETGEIPRKNLDVMKEAMVQAEEAAAEITRKL-EKQEKKRLKKEKK 452
EKL++ Q E L E + + V++E + ++ A+ RKL E++EK+RLK+E +
Sbjct: 552 EKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEAD--RKLREEEEKRRLKEEIE 609
Query: 453 RLAALALASSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGMEDPSISFSKPKKKKSF 512
R A A +E PE+ +KP K K + E E + S K KS
Sbjct: 610 RRRAEA---AEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKST 666
Query: 513 SKEELMSS-DLEETAGSTSIPKRKKSTPKEETVND 546
+ ++S D +++I K + P + +D
Sbjct: 667 HQAAIVSKIDSRLEQYTSAIEGTKSAKPTKPAASD 701
Score = 34.7 bits (78), Expect = 0.25
Identities = 41/196 (20%), Positives = 83/196 (42%), Gaps = 6/196 (3%)
Query: 399 EQVEERLSFYETGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRLAALA 458
E+ E R YE E K AEE E K E++E+++ K+ +
Sbjct: 151 EKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEK-EEEEEEKPKRGSIGENQVE 209
Query: 459 LASSENSSSTPEECEEMSEKPKKKKKQKP-QEVPQENGMEDPSISFSKPKKKKSFSKEEL 517
+ E ++ + EE MS K + ++P QE +E G ++ S ++ K ++ E
Sbjct: 210 VMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAER 269
Query: 518 MSSDLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGSKKKRKFSKEEPVSSGPEEAVG 577
+ EE + KK + + E+A + +++R+ ++E E+
Sbjct: 270 ARLEAEERE-RIKAEQDKKIADERARIEAEEKA---AAQERERREAEERERMREEEKRAA 325
Query: 578 KSSSKKKKKFHKASQE 593
+ + K++ +A++E
Sbjct: 326 EERQRIKEEEKRAAEE 341
Score = 32.7 bits (73), Expect = 0.97
Identities = 44/190 (23%), Positives = 76/190 (40%), Gaps = 37/190 (19%)
Query: 429 EEAAAEITRKLEKQEKKRLKKEKKRLAALALASSENS-SSTPEE---------------- 471
EE AA R+ +QE+ R K+E++ L + N+ +S P+E
Sbjct: 34 EEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDE 93
Query: 472 ---CEEMSEKPKKKKKQKPQEVPQENGMEDPSI---SFSKPKKK--------KSFSKEEL 517
E ++ + ++++K + QE + DP+I S S P ++ ++ KEE
Sbjct: 94 AAFLERLARREERRQK-RLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEK 152
Query: 518 MSS-----DLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGSKKKRKFSKEEPVSSGP 572
S ++EET T ++ EE + +E K KR E V
Sbjct: 153 SESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMV 212
Query: 573 EEAVGKSSSK 582
EE +S +
Sbjct: 213 EEKTTESQEE 222
Score = 32.3 bits (72), Expect = 1.3
Identities = 53/248 (21%), Positives = 100/248 (40%), Gaps = 54/248 (21%)
Query: 359 RAAAKNKGRISRYLANKCSIASRIDCFSEVPTSVFGEKLREQVEERLSFYETGEIPRKNL 418
RA + K ++ NK + + E T + GEK+ +++E + + + +
Sbjct: 374 RAEEEEKAKVEEQKRNK-QLEEKKHAMQE--TKIKGEKVEQKIEGKWVNEKKAQEDKLQT 430
Query: 419 DVMKEAMVQAEEAAAEITRKLEK-QEKK-----------RLKKEKK-------------- 452
V+K+ Q EE ++ K EK QE K ++KK+K+
Sbjct: 431 AVLKK---QGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKG 487
Query: 453 ---------RLAALALASSENSSSTPE-----ECEEMSEKPKKKKKQKPQEVPQENGMED 498
L +EN+ S P + +E P+ + ++ +E+ + G E
Sbjct: 488 FTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRG-ET 546
Query: 499 PSISFSKPKKKKSFSKEELMSSDLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGSKK 558
S F K K+K ++ + +LEE +R+K +EE EEA + ++
Sbjct: 547 ESEEFEKLKQK-----QQEAALELEELKKKRE--ERRKVLEEEEQRRKQEEADRKLREEE 599
Query: 559 KRKFSKEE 566
+++ KEE
Sbjct: 600 EKRRLKEE 607
>gi|151301228 formin binding protein 3 [Homo sapiens]
Length = 930
Score = 48.1 bits (113), Expect = 2e-05
Identities = 47/192 (24%), Positives = 81/192 (42%), Gaps = 14/192 (7%)
Query: 395 EKLREQVEERLSFYE-TGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKR 453
E +RE+ + +F + T E RK + K+ M E K +K KK K +KR
Sbjct: 741 EDIRERFVKEPAFEDITLESERKR--IFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKR 798
Query: 454 LAALALASSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGMEDPSISFSKPKKKKSFS 513
S S + ++ S KK+++ + + + + + S+ K KK K S
Sbjct: 799 ---------SRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKS 849
Query: 514 KEELMSSDLEETAGSTSIPKRKKSTPKE-ETVNDPEEAGHRSGSKKKRKFSKEEPVSSGP 572
K+ SD E+ K++K E + E+ H+S KK K S +SG
Sbjct: 850 KKRRHKSDSPESDAEREKDKKEKDRESEKDRTRQRSESKHKSPKKKTGKDSGNWD-TSGS 908
Query: 573 EEAVGKSSSKKK 584
E + G+ +++
Sbjct: 909 ELSEGELEKRRR 920
Score = 40.8 bits (94), Expect = 0.004
Identities = 47/199 (23%), Positives = 80/199 (40%), Gaps = 16/199 (8%)
Query: 398 REQVEERLSFYETGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQ---EKKRLKKEKKRL 454
RE+ +E + E K++ ++ + +I + K+ E L+ E+KR+
Sbjct: 706 REREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLESERKRI 765
Query: 455 AALALASSENSSSTPEECEEMSEKPKK-----KKKQKPQEVPQENGMEDPSISFSKPKKK 509
+ E+ EC+ K KK KK + + + D S SK K++
Sbjct: 766 FKDFMHVLEH------ECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQ 819
Query: 510 KSFSK--EELMSSDLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGSKKKRKFSKEEP 567
+S S+ E SS E + S +KKS + + PE R KK++ E+
Sbjct: 820 RSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEKD 879
Query: 568 VSSGPEEAVGKSSSKKKKK 586
+ E+ KS KK K
Sbjct: 880 RTRQRSESKHKSPKKKTGK 898
Score = 36.6 bits (83), Expect = 0.067
Identities = 40/169 (23%), Positives = 74/169 (43%), Gaps = 21/169 (12%)
Query: 430 EAAAEITRKLEKQEKKRLKKEKKRLAALALASSENSSSTPEECEEMSEKPKKKKKQKPQE 489
E A R+ EK+E +++K+++ A S ++ P E + + E +++ ++P
Sbjct: 699 EKAEAREREREKEEARKMKRKES-----AFKSMLKQAAPPIELDAVWEDIRERFVKEP-- 751
Query: 490 VPQENGMEDPSISFSKPKKKKSFS---KEELMSSDLEETAGSTSIPK--RKKSTPKEETV 544
ED ++ + + K F + E + S K RK+S + +
Sbjct: 752 -----AFEDITLESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSD 806
Query: 545 NDPEEAGHRSGSKKKRKFSKEEPVSSGPEEAVGKSSSKKKKKFHKASQE 593
+D ++ S SKKKR+ S+ S A + S KK KK K S++
Sbjct: 807 SDDDD----SHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKK 851
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 47.4 bits (111), Expect = 4e-05
Identities = 48/208 (23%), Positives = 93/208 (44%), Gaps = 12/208 (5%)
Query: 396 KLREQV--EERLSFYETGEIPRKNLDVM----KEAMVQAEEAAAEITRKLEKQ-EKKRLK 448
K+R + EE+++ E ++ RK+ +V+ +E ++ EE + R+ K+ E KR
Sbjct: 2149 KMRRMINKEEKMT-EEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGD 2207
Query: 449 KEKKRLAALA--LASSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGMEDPSISFSKP 506
K K++ ++ + S E+ S E + EK + ++ +E +E E+ + +
Sbjct: 2208 KPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEE 2267
Query: 507 KKKKSFSKEELMSSDLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGSKKKRKFSKEE 566
++K+ EE EE K+K+ ++E V + +E + +EE
Sbjct: 2268 ERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEE 2327
Query: 567 PVSSGPEEAVGKSSS--KKKKKFHKASQ 592
S EE V + KK+K+F Q
Sbjct: 2328 EESCSLEEEVDREKEILKKEKQFKLQEQ 2355
Score = 45.4 bits (106), Expect = 1e-04
Identities = 44/218 (20%), Positives = 88/218 (40%), Gaps = 27/218 (12%)
Query: 402 EERLSFYETGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRLAALALAS 461
E +L+ E K +KE + E++ +I +++ L K++K+LA
Sbjct: 2087 ERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKL 2146
Query: 462 SENSSSTPEECEEMSEKPKKKKKQKPQEV---PQENGMEDPSI---------------SF 503
+ + E+M+E+ K ++ + + +E G+E+ +
Sbjct: 2147 ANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRG 2206
Query: 504 SKPKKKKSFSKEEL---------MSSDLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRS 554
KPK+K S +E+ M S L+E S+ ++ +EE + EE
Sbjct: 2207 DKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEE 2266
Query: 555 GSKKKRKFSKEEPVSSGPEEAVGKSSSKKKKKFHKASQ 592
+K+ + +E+ V EE K KKK++ + +
Sbjct: 2267 EERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEE 2304
Score = 42.7 bits (99), Expect = 0.001
Identities = 44/218 (20%), Positives = 87/218 (39%), Gaps = 25/218 (11%)
Query: 402 EERLSFYETG-EIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRLAALALA 460
E RLS ++ +I + + + + E+ A RKL + ++ + KE+K +
Sbjct: 2108 ERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKL 2167
Query: 461 SSENSSSTPEECEE-----------------------MSEKPKKKKKQKPQEVP-QENGM 496
+ ++S ++ EE +KPK+K + EV +E+
Sbjct: 2168 ARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFS 2227
Query: 497 EDPSISFSKPKKKKSFSKEELMSSDLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGS 556
E+ + +K++S S EE + EE + + ++ +EE + +
Sbjct: 2228 EEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEK 2287
Query: 557 KKKRKFSKEEPVSSGPEEAVGKSSSKKKKKFHKASQED 594
KKK+K K+E V E K +++ S E+
Sbjct: 2288 KKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEE 2325
Score = 41.2 bits (95), Expect = 0.003
Identities = 37/173 (21%), Positives = 79/173 (45%), Gaps = 24/173 (13%)
Query: 394 GEKLREQVEERLSFYETGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKR 453
G+K +E+ ++ E+ E + ++ + + + + E ++E + E++E++ ++ ++
Sbjct: 2206 GDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREE 2265
Query: 454 LAALALASSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGMEDPSISFSKPKKKKSFS 513
+E EE +K K+KKK++ QE K++
Sbjct: 2266 EEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQE-----------------KEEVFEE 2308
Query: 514 KEELMSSDLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGSKKKRKFSKEE 566
KEE+MS EET + + ++S EE V+ +E KK+++F +E
Sbjct: 2309 KEEIMSE--EETESLSDEEEEEESCSLEEEVDREKEI-----LKKEKQFKLQE 2354
Score = 39.7 bits (91), Expect = 0.008
Identities = 47/180 (26%), Positives = 83/180 (46%), Gaps = 10/180 (5%)
Query: 391 SVFGEKLRE--QVEERLSFYE---TGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKK 445
++ +K+ E Q E+ L + E E+ D M+E + EE E + +E EKK
Sbjct: 1691 NILAQKVEELPQREQNLDWQEKELAQELEELEWD-MEELSWKEEELNQEEGKLVE--EKK 1747
Query: 446 RLKKEKKRLAALALASSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGMEDPSISFSK 505
+L +E++ LA SE + +E EE+ + K+K Q +++P+E
Sbjct: 1748 KLAEEEEALAWQREKLSEEETKLAQE-EELLIQEKEKLAQHKEKMPEEEERLGRKREQLI 1806
Query: 506 PKKKKSFSKEELMSSDLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGSKKKRKFSKE 565
KK K K E + +EE + I +KK+ +E+ N +E + K+ ++KE
Sbjct: 1807 EKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKK-NLAQEKEKLAQRKENLLYNKE 1865
Score = 36.6 bits (83), Expect = 0.067
Identities = 41/164 (25%), Positives = 73/164 (44%), Gaps = 15/164 (9%)
Query: 395 EKLREQVEERLSFYETGEIPRKNLDVMKEAM-VQAEEAAAEITRKLEKQEKKRLKKEKKR 453
++ +++ E L + E K V +E +Q E A I RK + EKKR ++E+K
Sbjct: 1536 QQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERK- 1594
Query: 454 LAALALASSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGMEDPSISFSKPKKKKSFS 513
LA E + +E +++++ +K + + + M F++ K++
Sbjct: 1595 -----LAQEEEKLA--QEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQ-KEETLAQ 1646
Query: 514 KEELMSSDLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGSK 557
+ E +S + E+ A KRKK K E V EE + G K
Sbjct: 1647 RGEKLSQEAEKLA-----QKRKKLAKKWEKVAREEEKLAKKGGK 1685
Score = 32.7 bits (73), Expect = 0.97
Identities = 33/155 (21%), Positives = 69/155 (44%), Gaps = 10/155 (6%)
Query: 440 EKQEKKRLKKEKKRLAALALASSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGMEDP 499
E+ EK+ L++E+K A S E EEM ++ KK K ++ ++V EN +
Sbjct: 1483 EEWEKRLLQEEEKLHQAGEKLSPE---------EEMLQEDKKLKWEEWKQV-WENMLSSK 1532
Query: 500 SISFSKPKKKKSFSKEELMSSDLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGSKKK 559
S +++ +EE+ E+ T + + K ++ + ++++
Sbjct: 1533 SKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEE 1592
Query: 560 RKFSKEEPVSSGPEEAVGKSSSKKKKKFHKASQED 594
RK ++EE + E + + K + + K +Q+D
Sbjct: 1593 RKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDD 1627
Score = 31.2 bits (69), Expect = 2.8
Identities = 46/220 (20%), Positives = 91/220 (41%), Gaps = 22/220 (10%)
Query: 395 EKLREQVEERLSFYETGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRL 454
EKL ++ E L E +K L +K + + A++ KL QEK+ + K+K++L
Sbjct: 1851 EKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLT-QEKETVIKKKEKL 1909
Query: 455 AAL--ALASSENSSSTPEE----------CEEMSEKPKKKKKQKPQEVPQENGMEDPSIS 502
A L E+S + +E E+ + KK+ + + +E +
Sbjct: 1910 AETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKR 1969
Query: 503 FSKPKKKKSFSKEELMSSDLEETAGSTSIP-------KRKKSTPKEETVNDPEEAGHRSG 555
++ K + KE L + ET+ + +RK S ++ +++
Sbjct: 1970 LAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEES 2029
Query: 556 --SKKKRKFSKEEPVSSGPEEAVGKSSSKKKKKFHKASQE 593
+K K +F++ + + + + K+S K KK S+E
Sbjct: 2030 EIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKE 2069
Score = 30.0 bits (66), Expect = 6.3
Identities = 35/192 (18%), Positives = 86/192 (44%), Gaps = 11/192 (5%)
Query: 385 FSEVPTSVFGEKLREQVEERLSFYETGEIPRK------NLDVMKEAMVQAEEAAAEITRK 438
F E G+++ ++ EE+ +F ++ + RK + +K M + E +E +
Sbjct: 1375 FLEPGNVTMGKEISKK-EEKKTFQKSPKQGRKAVQKERKVGKIKREMTKEERDMSEEVEE 1433
Query: 439 LEKQEKKRLKKEKKRLAALALASSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGMED 498
+ E+K +K+E K + S ++ +E +++ + +K K +E + E+
Sbjct: 1434 MATLEEKVVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEEWEKRLLQEE 1493
Query: 499 PSISFS----KPKKKKSFSKEELMSSDLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRS 554
+ + P+++ ++L + ++ + K K+ K+E EE R
Sbjct: 1494 EKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSRE 1553
Query: 555 GSKKKRKFSKEE 566
G +K+++ ++E+
Sbjct: 1554 GEEKEQQVTEEQ 1565
>gi|50962817 TWIST neighbor [Homo sapiens]
Length = 338
Score = 47.4 bits (111), Expect = 4e-05
Identities = 36/120 (30%), Positives = 53/120 (44%), Gaps = 16/120 (13%)
Query: 483 KKQKPQEVPQENGMEDPSISFSKPKKKKSFSKEELMSSDLEETAGSTSIPKRKKSTPKEE 542
K+ + E ENG E+ + KPKKKK E D +G+T + TP EE
Sbjct: 206 KRSEVSEEVTENGTEEAA---KKPKKKKKKKDPETYEVD----SGTTKLADDADDTPMEE 258
Query: 543 TVND---------PEEAGHRSGSKKKRKFSKEEPVSSGPEEAVGKSSSKKKKKFHKASQE 593
+ EE + KK ++ ++PV G + + +S KKKKK K S+E
Sbjct: 259 SALQNTNNANGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKRKHSEE 318
Score = 36.2 bits (82), Expect = 0.087
Identities = 32/124 (25%), Positives = 49/124 (39%), Gaps = 11/124 (8%)
Query: 423 EAMVQAEEAAAEITRKLEKQEKKRLKKEKKRLAALALASSENSSSTPEECEEMS------ 476
E + E E K K++KK+ E + + ++++ TP E +
Sbjct: 209 EVSEEVTENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDTPMEESALQNTNNAN 268
Query: 477 -----EKPKKKKKQKPQEVPQENGMEDPSISFSKPKKKKSFSKEELMSSDLEETAGSTSI 531
E KKKKK+K QEV ++ + S S K K+ S + E T
Sbjct: 269 GIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKRKHSEEAEFTPPLKCS 328
Query: 532 PKRK 535
PKRK
Sbjct: 329 PKRK 332
>gi|125656165 THO complex 2 [Homo sapiens]
Length = 1593
Score = 47.0 bits (110), Expect = 5e-05
Identities = 43/218 (19%), Positives = 88/218 (40%), Gaps = 29/218 (13%)
Query: 386 SEVPTSVFGEKLREQVEERLSFYETGEIPRKNLDVMKEAMVQAEEAAAEI---------- 435
S VP S E REQ ++ + + + +K+++++ +E++A++
Sbjct: 1393 SPVPRSDIPEPEREQKRRKIDTHPSPS----HSSTVKDSLIELKESSAKLYINHTPPPLS 1448
Query: 436 TRKLEKQEKKRLKKEKKRLAALALASSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENG 495
K + +KK L K ++R S E ++ +E ++ P ++ +
Sbjct: 1449 KSKEREMDKKDLDKSRER-------SREREKKDEKDRKERKRDHSNNDREVPPDLTKRRK 1501
Query: 496 MEDPSISFSKPKKKKSFSKEELMSSDLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRSG 555
E+ ++ SK K + D E+ +S ++ + K E ++ G +
Sbjct: 1502 EENGTMGVSKHKSESPCESPYPNEKDKEKNKSKSSGKEKGSDSFKSEKMDKISSGGKKES 1561
Query: 556 SKKKRKFSKEEPVSSGPEEAVGKSSSKKKKKFHKASQE 593
K K K+E S S K++KK HK+S +
Sbjct: 1562 RHDKEKIEKKEKRDS--------SGGKEEKKHHKSSDK 1591
Score = 39.3 bits (90), Expect = 0.010
Identities = 46/203 (22%), Positives = 79/203 (38%), Gaps = 20/203 (9%)
Query: 409 ETGEIPR-KNLDVMKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKR---LAALALA---- 460
ETGE +N+ ++ ++ + + LE++ K ++EK++ L ALA+
Sbjct: 1113 ETGEYTHIRNILIVLTKILPWYPKVLNLGQALERRVHKICQEEKEKRPDLYALAMGYSGQ 1172
Query: 461 -SSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGMEDPSISFSKPKKKKSFSKEELMS 519
S S PE + P + Q P G S S K S EE
Sbjct: 1173 LKSRKSYMIPENEFHHKDPPPRNAVASVQNGP---GGGPSSSSIGSASKSDESSTEETDK 1229
Query: 520 SDLEETAGSTSIPKRKKSTPKEETVNDPE--------EAGHRSGSKKKRKFSKEEPVSSG 571
S G ++ K +TPK + N + + K+K K KE+ ++
Sbjct: 1230 SRERSQCGVKAVNKASSTTPKGNSSNGNSGSNSNKAVKENDKEKGKEKEKEKKEKTPATT 1289
Query: 572 PEEAVGKSSSKKKKKFHKASQED 594
PE V K+K K + ++++
Sbjct: 1290 PEARVLGKDGKEKPKEERPNKDE 1312
Score = 39.3 bits (90), Expect = 0.010
Identities = 33/155 (21%), Positives = 66/155 (42%), Gaps = 11/155 (7%)
Query: 440 EKQEKKRLKKEKKRLAALALASSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGMEDP 499
+K++ K +KEKK + ++TPE + +K K+++P + E E
Sbjct: 1270 DKEKGKEKEKEKKE---------KTPATTPEARVLGKDGKEKPKEERPNK--DEKARETK 1318
Query: 500 SISFSKPKKKKSFSKEELMSSDLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGSKKK 559
+ K+K+ F KEE + +T + K + +E+ + + SK+
Sbjct: 1319 ERTPKSDKEKEKFKKEEKAKDEKFKTTVPNAESKSTQEREREKEPSRERDIAKEMKSKEN 1378
Query: 560 RKFSKEEPVSSGPEEAVGKSSSKKKKKFHKASQED 594
K ++ PVS + V +S + ++ K + D
Sbjct: 1379 VKGGEKTPVSGSLKSPVPRSDIPEPEREQKRRKID 1413
Score = 38.1 bits (87), Expect = 0.023
Identities = 35/164 (21%), Positives = 66/164 (40%), Gaps = 10/164 (6%)
Query: 427 QAEEAAAEITRKLEKQEKKRLKKEKKRLAALALASSENSSSTPEECEEMSEKPKKKKKQK 486
+++E++ E T K ++ + +K K + +S N +S + + E K+K K+K
Sbjct: 1218 KSDESSTEETDKSRERSQCGVKAVNKASSTTPKGNSSNGNSGSNSNKAVKENDKEKGKEK 1277
Query: 487 PQEVPQENGMEDPSISF------SKPKKKKSFSKEELMSSDLEETAGSTSIPKRKKSTPK 540
+E ++ P KPK+++ +K+E E T S K K+ K
Sbjct: 1278 EKEKKEKTPATTPEARVLGKDGKEKPKEERP-NKDEKARETKERTPKS---DKEKEKFKK 1333
Query: 541 EETVNDPEEAGHRSGSKKKRKFSKEEPVSSGPEEAVGKSSSKKK 584
EE D + ++ K +E E + K K+
Sbjct: 1334 EEKAKDEKFKTTVPNAESKSTQEREREKEPSRERDIAKEMKSKE 1377
Score = 33.5 bits (75), Expect = 0.57
Identities = 39/183 (21%), Positives = 68/183 (37%), Gaps = 15/183 (8%)
Query: 414 PRKNLDVMKEAMVQAEEAAAEIT-------RKLEKQEKKRLKKEKKRLAALALASSENSS 466
P + D+ KE + E T + + + ++E+KR S +SS
Sbjct: 1363 PSRERDIAKEMKSKENVKGGEKTPVSGSLKSPVPRSDIPEPEREQKRRKIDTHPSPSHSS 1422
Query: 467 STPEECEEMSEKPKK---KKKQKPQEVPQENGMEDPSISFSKPKKKKSFSKEELMSSDLE 523
+ + E+ E K P +E M+ + S+ + ++ K+E D +
Sbjct: 1423 TVKDSLIELKESSAKLYINHTPPPLSKSKEREMDKKDLDKSRERSREREKKDE---KDRK 1479
Query: 524 ETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGSKKKRKFSKEEPVSSGPEEAVGKSSSKK 583
E S + P + T EE G SK K + E P + ++ KS S
Sbjct: 1480 ERKRDHS--NNDREVPPDLTKRRKEENGTMGVSKHKSESPCESPYPNEKDKEKNKSKSSG 1537
Query: 584 KKK 586
K+K
Sbjct: 1538 KEK 1540
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 47.0 bits (110), Expect = 5e-05
Identities = 45/204 (22%), Positives = 91/204 (44%), Gaps = 8/204 (3%)
Query: 395 EKLREQVEERLSFYETGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRL 454
EK+REQ E+ E + + +E M + EE E+ K+ +QEK R ++E+KR
Sbjct: 309 EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIR-EQEEKRQ 367
Query: 455 AALALASSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGMEDPSISFSKPKKKKSFSK 514
+ E E+ +M + +K ++Q+ + QE M++ + ++K +
Sbjct: 368 EEEKIREQEKRQ---EQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQE 424
Query: 515 EELMSSDLEETAGSTSI-PKRKKSTPKEETVNDPEEAGHRSGSK---KKRKFSKEEPVSS 570
EE+ + + I + KK +EE + + EE K ++ K ++E
Sbjct: 425 EEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQ 484
Query: 571 GPEEAVGKSSSKKKKKFHKASQED 594
EE + + K +++ K +++
Sbjct: 485 EQEEKMRRQEEKIREQEKKIREQE 508
Score = 46.2 bits (108), Expect = 8e-05
Identities = 45/210 (21%), Positives = 89/210 (42%), Gaps = 20/210 (9%)
Query: 395 EKLREQVEERLSFYETGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRL 454
EK+ Q E+ E + + + +E M + EE E K+ +QE+ +KE+K
Sbjct: 288 EKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK-- 345
Query: 455 AALALASSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGMEDPSISFSKPKKKKSFSK 514
+ E E+ E EK ++++K + QE QE + ++++ +
Sbjct: 346 ----IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 401
Query: 515 EELMSSDLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGSK----------KKRKFSK 564
+E M + EE G + +K +EE + + EE R K ++ K +
Sbjct: 402 QEEMMQEQEEKMGE----QEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIRE 457
Query: 565 EEPVSSGPEEAVGKSSSKKKKKFHKASQED 594
+E + EE +G+ K ++ K +++
Sbjct: 458 QEEMMQEQEEKMGEQEGKMCEQEAKMQEQE 487
Score = 45.4 bits (106), Expect = 1e-04
Identities = 42/172 (24%), Positives = 74/172 (43%), Gaps = 10/172 (5%)
Query: 395 EKLREQVEERLSFYETGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRL 454
EK+REQ E+ E + + + +E M + EE E K+ +QE+K ++EKK +
Sbjct: 390 EKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKK-I 448
Query: 455 AALALASSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGMEDPSISFSKPKKK----- 509
E E+ E+M E+ K +Q+ + QE M + +KK
Sbjct: 449 REQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQE 508
Query: 510 KSFSKEELMSSDLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGSKKKRK 561
+ ++E M + EE + +K +EE + + EE R K + +
Sbjct: 509 EKIREQEEMMQEQEEKMWE----QEEKMCEQEEKMQEQEEKMRRQEEKMREQ 556
Score = 29.6 bits (65), Expect = 8.2
Identities = 21/70 (30%), Positives = 35/70 (50%), Gaps = 1/70 (1%)
Query: 395 EKLREQVEERLSFYETGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKK-RLKKEKKR 453
EK+REQ ++ E + + +E M + EE E K+++QE+K R ++EK R
Sbjct: 495 EKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMR 554
Query: 454 LAALALASSE 463
+ L E
Sbjct: 555 EQEVRLRQQE 564
>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
Length = 2803
Score = 47.0 bits (110), Expect = 5e-05
Identities = 50/240 (20%), Positives = 101/240 (42%), Gaps = 34/240 (14%)
Query: 388 VPTSVFGEKLREQVEERLSFYETGEIPRKNLDVMKEAMVQ-AEEAAAEITRKLEKQEKKR 446
VPT++ K++++ + + S T + L +E + + A+EA +E+ ++L K EKK
Sbjct: 304 VPTNLKPSKIKQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTEKKA 363
Query: 447 LKKEKK---RLAALALASSENSSSTPEE--------------------CEEMSEKPKKKK 483
+ +K + A +E+S + E EE +K KK+
Sbjct: 364 KESSEKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEI 423
Query: 484 KQKPQEVPQENGMEDPSISFSKPKKK-------KSFSKEEL--MSSDLEETAGSTSIPKR 534
K++ +E+ ++ G ++ K +K+ K SK +L + ++ +T +P R
Sbjct: 424 KKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTLYKAKVPGR 483
Query: 535 KKSTPKEETVNDPEEAGHRSGSKKKRKFSKEEPVSSGPEEAVGKSSSKKKKKFHKASQED 594
K + + +E + +K + P SG E V S + F + +E+
Sbjct: 484 VK-IDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQDFEEMKREE 542
Score = 30.4 bits (67), Expect = 4.8
Identities = 26/150 (17%), Positives = 61/150 (40%), Gaps = 10/150 (6%)
Query: 409 ETGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRLAA---LALASSENS 465
+ G +P + +E ++ + E + +++++E+ L +++ L ++E
Sbjct: 508 QKGTVPLPTISGHRELVLSSPEDLTQDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEG 567
Query: 466 ------SSTPEECEEMS-EKPKKKKKQKPQEVPQENGMEDPSISFSKPKKKKSFSKEELM 518
TP + E+ K+K+ EVP+E G +D + +++ + EE
Sbjct: 568 PPSTAIQGTPPSVPGLGQEEHVMKEKELVPEVPEEQGSKDRGLDSGAETEEEKDTWEEKK 627
Query: 519 SSDLEETAGSTSIPKRKKSTPKEETVNDPE 548
+ E T + + KE+ + E
Sbjct: 628 QREAERLPDRTEAREESEPEVKEDVIEKAE 657
>gi|7661950 SH2 domain binding protein 1 [Homo sapiens]
Length = 1173
Score = 47.0 bits (110), Expect = 5e-05
Identities = 52/191 (27%), Positives = 84/191 (43%), Gaps = 14/191 (7%)
Query: 415 RKNLDVMKEAMVQAEEAAAEITRKLEK-QEKKRL--KKEKKRLA---ALALASSENSSST 468
RK + +E + E+ + +KL K QE+KRL K+E+K+L A + ++N
Sbjct: 832 RKQDEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNILMF 891
Query: 469 PEECEEMSEKPKK----KKKQKPQEVPQ-ENGMEDPSISFSKPKKKKSFSKEELMSSDLE 523
E E EK + ++ +K E + N D + SK KK++ S E D E
Sbjct: 892 TGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEE 951
Query: 524 ETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGSKKKRKFSKEEPVSSGPEEAVGKSSSKK 583
G K+++ PK E +D +E + KK+R E+ + PE K
Sbjct: 952 ---GGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKI 1008
Query: 584 KKKFHKASQED 594
K K +S +D
Sbjct: 1009 KSKAIISSSDD 1019
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.129 0.347
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,776,838
Number of Sequences: 37866
Number of extensions: 943964
Number of successful extensions: 10863
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 209
Number of HSP's successfully gapped in prelim test: 844
Number of HSP's that attempted gapping in prelim test: 5940
Number of HSP's gapped (non-prelim): 3418
length of query: 594
length of database: 18,247,518
effective HSP length: 108
effective length of query: 486
effective length of database: 14,157,990
effective search space: 6880783140
effective search space used: 6880783140
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.