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Search of human proteins with 32313599
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|32313599 serine peptidase inhibitor, Kunitz type 1 isoform 1
precursor [Homo sapiens]
(529 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|32313599 serine peptidase inhibitor, Kunitz type 1 isoform 1 ... 1127 0.0
gi|74027265 serine peptidase inhibitor, Kunitz type 1 isoform 2 ... 1084 0.0
gi|4504329 serine peptidase inhibitor, Kunitz type 1 isoform 2 p... 1084 0.0
gi|10863909 serine protease inhibitor, Kunitz type, 2 [Homo sapi... 118 2e-26
gi|239787919 low density lipoprotein receptor-related protein 11... 106 5e-23
gi|5730091 tissue factor pathway inhibitor 2 [Homo sapiens] 96 8e-20
gi|5454114 tissue factor pathway inhibitor isoform a precursor [... 92 1e-18
gi|4502067 alpha-1-microglobulin/bikunin preproprotein [Homo sap... 65 2e-10
gi|41406055 amyloid beta A4 protein isoform b precursor [Homo sa... 64 3e-10
gi|4502167 amyloid beta A4 protein isoform a precursor [Homo sap... 63 6e-10
gi|209915573 amyloid beta A4 protein isoform f precursor [Homo s... 63 6e-10
gi|214010181 amyloid beta (A4) precursor-like protein 2 isoform ... 62 1e-09
gi|4502147 amyloid beta (A4) precursor-like protein 2 isoform 1 ... 62 1e-09
gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo s... 61 3e-09
gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo s... 61 3e-09
gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo ... 61 3e-09
gi|145309328 papilin [Homo sapiens] 60 5e-09
gi|73760409 tissue factor pathway inhibitor isoform b precursor ... 60 6e-09
gi|16751923 WAP, follistatin/kazal, immunoglobulin, kunitz and n... 59 1e-08
gi|28212222 WFIKKN2 protein [Homo sapiens] 58 2e-08
gi|31563528 serine peptidase inhibitor-like, with Kunitz and WAP... 57 4e-08
gi|10732863 serine peptidase inhibitor-like, with Kunitz and WAP... 57 4e-08
gi|154759255 collagen, type XXVIII precursor [Homo sapiens] 54 3e-07
gi|4507157 sortilin-related receptor containing LDLR class A rep... 51 3e-06
gi|65301164 very low density lipoprotein receptor isoform b [Hom... 50 7e-06
gi|65301167 very low density lipoprotein receptor isoform a [Hom... 50 7e-06
gi|189571689 serine protease inhibitor, Kunitz type, 3 [Homo sap... 50 7e-06
gi|153946389 WAP four-disulfide core domain 8 precursor [Homo sa... 49 9e-06
gi|153946387 WAP four-disulfide core domain 8 precursor [Homo sa... 49 9e-06
gi|119709832 low density lipoprotein receptor-related protein 5 ... 49 1e-05
>gi|32313599 serine peptidase inhibitor, Kunitz type 1 isoform 1
precursor [Homo sapiens]
Length = 529
Score = 1127 bits (2915), Expect = 0.0
Identities = 529/529 (100%), Positives = 529/529 (100%)
Query: 1 MAPARTMARARLAPAGIPAVALWLLCTLGLQGTQAGPPPAPPGLPAGADCLNSFTAGVPG 60
MAPARTMARARLAPAGIPAVALWLLCTLGLQGTQAGPPPAPPGLPAGADCLNSFTAGVPG
Sbjct: 1 MAPARTMARARLAPAGIPAVALWLLCTLGLQGTQAGPPPAPPGLPAGADCLNSFTAGVPG 60
Query: 61 FVLDTNASVSNGATFLESPTVRRGWDCVRACCTTQNCNLALVELQPDRGEDAIAACFLIN 120
FVLDTNASVSNGATFLESPTVRRGWDCVRACCTTQNCNLALVELQPDRGEDAIAACFLIN
Sbjct: 61 FVLDTNASVSNGATFLESPTVRRGWDCVRACCTTQNCNLALVELQPDRGEDAIAACFLIN 120
Query: 121 CLYEQNFVCKFAPREGFINYLTREVYRSYRQLRTQGFGGSGIPKAWAGIDLKVQPQEPLV 180
CLYEQNFVCKFAPREGFINYLTREVYRSYRQLRTQGFGGSGIPKAWAGIDLKVQPQEPLV
Sbjct: 121 CLYEQNFVCKFAPREGFINYLTREVYRSYRQLRTQGFGGSGIPKAWAGIDLKVQPQEPLV 180
Query: 181 LKDVENTDWRLLRGDTDVRVERKDPNQVELWGLKEGTYLFQLTVTSSDHPEDTANVTVTV 240
LKDVENTDWRLLRGDTDVRVERKDPNQVELWGLKEGTYLFQLTVTSSDHPEDTANVTVTV
Sbjct: 181 LKDVENTDWRLLRGDTDVRVERKDPNQVELWGLKEGTYLFQLTVTSSDHPEDTANVTVTV 240
Query: 241 LSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILAC 300
LSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILAC
Sbjct: 241 LSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILAC 300
Query: 301 RGVQGGPLRGSSGAQATFPQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNC 360
RGVQGGPLRGSSGAQATFPQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNC
Sbjct: 301 RGVQGGPLRGSSGAQATFPQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNC 360
Query: 361 PDASDEAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFT 420
PDASDEAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFT
Sbjct: 361 PDASDEAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFT 420
Query: 421 YGGCYGNKNNFEEEQQCLESCRGISKKDVFGLRREIPIPSTGSVEMAVAVFLVICIVVVV 480
YGGCYGNKNNFEEEQQCLESCRGISKKDVFGLRREIPIPSTGSVEMAVAVFLVICIVVVV
Sbjct: 421 YGGCYGNKNNFEEEQQCLESCRGISKKDVFGLRREIPIPSTGSVEMAVAVFLVICIVVVV 480
Query: 481 AILGYCFFKNQRKDFHGHHHHPPPTPASSTVSTTEDTEHLVYNHTTRPL 529
AILGYCFFKNQRKDFHGHHHHPPPTPASSTVSTTEDTEHLVYNHTTRPL
Sbjct: 481 AILGYCFFKNQRKDFHGHHHHPPPTPASSTVSTTEDTEHLVYNHTTRPL 529
>gi|74027265 serine peptidase inhibitor, Kunitz type 1 isoform 2
precursor [Homo sapiens]
Length = 513
Score = 1084 bits (2804), Expect = 0.0
Identities = 513/529 (96%), Positives = 513/529 (96%), Gaps = 16/529 (3%)
Query: 1 MAPARTMARARLAPAGIPAVALWLLCTLGLQGTQAGPPPAPPGLPAGADCLNSFTAGVPG 60
MAPARTMARARLAPAGIPAVALWLLCTLGLQGTQAGPPPAPPGLPAGADCLNSFTAGVPG
Sbjct: 1 MAPARTMARARLAPAGIPAVALWLLCTLGLQGTQAGPPPAPPGLPAGADCLNSFTAGVPG 60
Query: 61 FVLDTNASVSNGATFLESPTVRRGWDCVRACCTTQNCNLALVELQPDRGEDAIAACFLIN 120
FVLDTNASVSNGATFLESPTVRRGWDCVRACCTTQNCNLALVELQPDRGEDAIAACFLIN
Sbjct: 61 FVLDTNASVSNGATFLESPTVRRGWDCVRACCTTQNCNLALVELQPDRGEDAIAACFLIN 120
Query: 121 CLYEQNFVCKFAPREGFINYLTREVYRSYRQLRTQGFGGSGIPKAWAGIDLKVQPQEPLV 180
CLYEQNFVCKFAPREGFINYLTREVYRSYRQLRTQGFGGSGIPKAWAGIDLKVQPQEPLV
Sbjct: 121 CLYEQNFVCKFAPREGFINYLTREVYRSYRQLRTQGFGGSGIPKAWAGIDLKVQPQEPLV 180
Query: 181 LKDVENTDWRLLRGDTDVRVERKDPNQVELWGLKEGTYLFQLTVTSSDHPEDTANVTVTV 240
LKDVENTDWRLLRGDTDVRVERKDPNQVELWGLKEGTYLFQLTVTSSDHPEDTANVTVTV
Sbjct: 181 LKDVENTDWRLLRGDTDVRVERKDPNQVELWGLKEGTYLFQLTVTSSDHPEDTANVTVTV 240
Query: 241 LSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILAC 300
LSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILAC
Sbjct: 241 LSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILAC 300
Query: 301 RGVQGGPLRGSSGAQATFPQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNC 360
RGV QGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNC
Sbjct: 301 RGV----------------QGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNC 344
Query: 361 PDASDEAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFT 420
PDASDEAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFT
Sbjct: 345 PDASDEAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFT 404
Query: 421 YGGCYGNKNNFEEEQQCLESCRGISKKDVFGLRREIPIPSTGSVEMAVAVFLVICIVVVV 480
YGGCYGNKNNFEEEQQCLESCRGISKKDVFGLRREIPIPSTGSVEMAVAVFLVICIVVVV
Sbjct: 405 YGGCYGNKNNFEEEQQCLESCRGISKKDVFGLRREIPIPSTGSVEMAVAVFLVICIVVVV 464
Query: 481 AILGYCFFKNQRKDFHGHHHHPPPTPASSTVSTTEDTEHLVYNHTTRPL 529
AILGYCFFKNQRKDFHGHHHHPPPTPASSTVSTTEDTEHLVYNHTTRPL
Sbjct: 465 AILGYCFFKNQRKDFHGHHHHPPPTPASSTVSTTEDTEHLVYNHTTRPL 513
>gi|4504329 serine peptidase inhibitor, Kunitz type 1 isoform 2
precursor [Homo sapiens]
Length = 513
Score = 1084 bits (2804), Expect = 0.0
Identities = 513/529 (96%), Positives = 513/529 (96%), Gaps = 16/529 (3%)
Query: 1 MAPARTMARARLAPAGIPAVALWLLCTLGLQGTQAGPPPAPPGLPAGADCLNSFTAGVPG 60
MAPARTMARARLAPAGIPAVALWLLCTLGLQGTQAGPPPAPPGLPAGADCLNSFTAGVPG
Sbjct: 1 MAPARTMARARLAPAGIPAVALWLLCTLGLQGTQAGPPPAPPGLPAGADCLNSFTAGVPG 60
Query: 61 FVLDTNASVSNGATFLESPTVRRGWDCVRACCTTQNCNLALVELQPDRGEDAIAACFLIN 120
FVLDTNASVSNGATFLESPTVRRGWDCVRACCTTQNCNLALVELQPDRGEDAIAACFLIN
Sbjct: 61 FVLDTNASVSNGATFLESPTVRRGWDCVRACCTTQNCNLALVELQPDRGEDAIAACFLIN 120
Query: 121 CLYEQNFVCKFAPREGFINYLTREVYRSYRQLRTQGFGGSGIPKAWAGIDLKVQPQEPLV 180
CLYEQNFVCKFAPREGFINYLTREVYRSYRQLRTQGFGGSGIPKAWAGIDLKVQPQEPLV
Sbjct: 121 CLYEQNFVCKFAPREGFINYLTREVYRSYRQLRTQGFGGSGIPKAWAGIDLKVQPQEPLV 180
Query: 181 LKDVENTDWRLLRGDTDVRVERKDPNQVELWGLKEGTYLFQLTVTSSDHPEDTANVTVTV 240
LKDVENTDWRLLRGDTDVRVERKDPNQVELWGLKEGTYLFQLTVTSSDHPEDTANVTVTV
Sbjct: 181 LKDVENTDWRLLRGDTDVRVERKDPNQVELWGLKEGTYLFQLTVTSSDHPEDTANVTVTV 240
Query: 241 LSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILAC 300
LSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILAC
Sbjct: 241 LSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILAC 300
Query: 301 RGVQGGPLRGSSGAQATFPQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNC 360
RGV QGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNC
Sbjct: 301 RGV----------------QGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNC 344
Query: 361 PDASDEAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFT 420
PDASDEAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFT
Sbjct: 345 PDASDEAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFT 404
Query: 421 YGGCYGNKNNFEEEQQCLESCRGISKKDVFGLRREIPIPSTGSVEMAVAVFLVICIVVVV 480
YGGCYGNKNNFEEEQQCLESCRGISKKDVFGLRREIPIPSTGSVEMAVAVFLVICIVVVV
Sbjct: 405 YGGCYGNKNNFEEEQQCLESCRGISKKDVFGLRREIPIPSTGSVEMAVAVFLVICIVVVV 464
Query: 481 AILGYCFFKNQRKDFHGHHHHPPPTPASSTVSTTEDTEHLVYNHTTRPL 529
AILGYCFFKNQRKDFHGHHHHPPPTPASSTVSTTEDTEHLVYNHTTRPL
Sbjct: 465 AILGYCFFKNQRKDFHGHHHHPPPTPASSTVSTTEDTEHLVYNHTTRPL 513
>gi|10863909 serine protease inhibitor, Kunitz type, 2 [Homo
sapiens]
Length = 252
Score = 118 bits (295), Expect = 2e-26
Identities = 71/242 (29%), Positives = 106/242 (43%), Gaps = 54/242 (22%)
Query: 244 KQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGV 303
+ D+CL S VGRCR S PRW+Y+ T+ C+ FVYGGC GN NNYL +EEC+ C V
Sbjct: 32 RSIHDFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATV 91
Query: 304 QGGPLRGSSGAQATFPQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDA 363
++G AT + N D+
Sbjct: 92 ----TENATGDLAT---------------------------------------SRNAADS 108
Query: 364 SDEAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGG 423
S +A + S ++ + +C TG C+ S PRWY++ C F YGG
Sbjct: 109 SVPSAPRRQDSEDHSSDMFNY---EEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGG 165
Query: 424 CYGNKNNFEEEQQCLESCRGISKKDVFGLRREIPIPSTGSVEMAVAVFLVICIVVVVAIL 483
C GNKN++ E+ C+ C F + P+P V + +F+++ I+ + A +
Sbjct: 166 CRGNKNSYRSEEACMLRC--------FRQQENPPLPLGSKVVVLAGLFVMVLILFLGASM 217
Query: 484 GY 485
Y
Sbjct: 218 VY 219
Score = 80.1 bits (196), Expect = 5e-15
Identities = 37/82 (45%), Positives = 44/82 (53%), Gaps = 10/82 (12%)
Query: 226 SSDHPEDTANVTVTVLSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLG 285
S DH D N E+YC A+ G CR SFPRWY+D C +F+YGGC G
Sbjct: 119 SEDHSSDMFNY----------EEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRG 168
Query: 286 NKNNYLREEECILACRGVQGGP 307
NKN+Y EE C+L C Q P
Sbjct: 169 NKNSYRSEEACMLRCFRQQENP 190
>gi|239787919 low density lipoprotein receptor-related protein 11
[Homo sapiens]
Length = 500
Score = 106 bits (265), Expect = 5e-23
Identities = 95/308 (30%), Positives = 139/308 (45%), Gaps = 55/308 (17%)
Query: 36 GPPPAPPGLPAGADCLNSFTAGVPGFVLDTNASVSNGATFLESPTVRRGW-DCVRACCTT 94
GP PG +G + +P ++ T S++ GA+FL +P RGW CV ACC+
Sbjct: 84 GPQEDCPGPGSGG------YSAMPDAIIRTKDSLAAGASFLRAPAAVRGWRQCVAACCSE 137
Query: 95 QNCNLALVELQPDRGED--AIAACFLINCLYEQNFVCKFAPREGFINY-LTRE----VYR 147
C++A+VEL P R A+ C+L NC VCKFA G+ +Y L+R
Sbjct: 138 PRCSVAVVEL-PRRPAPPAAVLGCYLFNCTARGRNVCKFALHSGYSSYSLSRAPDGAALA 196
Query: 148 SYRQLRTQGFGGSGIPKAWAGIDLKVQPQEPLVLKDVENTD--------WRLLRGDTDVR 199
+ R Q + KA + L + P + +VL E+TD W LL+GD V
Sbjct: 197 TARASPRQEKDAPPLSKAGQDVVLHL-PTDGVVLDGRESTDDHAIVQYEWALLQGDPSVD 255
Query: 200 VERKDPNQVELWGLKEGTYLFQLTVTSSDHPEDTANVTVTVLSTKQTEDYCLASNKVGRC 259
++ ++L L+EGTY FQLTVT + + NV+VTVL A+ G C
Sbjct: 256 MKVPQSGTLKLSHLQEGTYTFQLTVTDTAGQRSSDNVSVTVLR---------AAYSTGGC 306
Query: 260 RGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQGGPLRGSSGAQATFP 319
+ R+++ F GC + LAC GVQ P G+ F
Sbjct: 307 LHTCSRYHF---------FCDDGCC---------IDITLACDGVQQCP----DGSDEDFC 344
Query: 320 QGPSMERR 327
Q ++R+
Sbjct: 345 QNLGLDRK 352
Score = 50.1 bits (118), Expect = 5e-06
Identities = 20/40 (50%), Positives = 22/40 (55%)
Query: 331 CSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACE 370
C TC F C +GCCID L CD CPD SDE C+
Sbjct: 306 CLHTCSRYHFFCDDGCCIDITLACDGVQQCPDGSDEDFCQ 345
>gi|5730091 tissue factor pathway inhibitor 2 [Homo sapiens]
Length = 235
Score = 95.9 bits (237), Expect = 8e-20
Identities = 69/210 (32%), Positives = 88/210 (41%), Gaps = 29/210 (13%)
Query: 243 TKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRG 302
T + CL G CR R+YYD Q C+ F+YGGC GN NN+ E C AC
Sbjct: 29 TGNNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWR 88
Query: 303 VQGGP----LRGSSGAQATFPQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFL-ECDDT 357
++ P L+ S Q C G+ + F S+ C F C
Sbjct: 89 IEKVPKVCRLQVSVDDQ---------------CEGSTEKYFFNLSSMTCEKFFSGGCHRN 133
Query: 358 PNCPDASDEAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCA 417
DEA C GF ++I PS C D GLC ++ R+Y+NP C
Sbjct: 134 RIENRFPDEATC----MGFCAPKKI--PS---FCYSPKDEGLCSANVTRYYFNPRYRTCD 184
Query: 418 RFTYGGCYGNKNNFEEEQQCLESCRGISKK 447
FTY GC GN NNF + C +C KK
Sbjct: 185 AFTYTGCGGNDNNFVSREDCKRACAKALKK 214
>gi|5454114 tissue factor pathway inhibitor isoform a precursor
[Homo sapiens]
Length = 304
Score = 92.0 bits (227), Expect = 1e-18
Identities = 62/211 (29%), Positives = 87/211 (41%), Gaps = 49/211 (23%)
Query: 232 DTANVTVTVLSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYL 291
D AN + ++ D+C G CRG R++Y+ + C+ F YGGCLGN NN+
Sbjct: 107 DNANRIIKTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFE 166
Query: 292 REEECILACRGVQGGPLRGSSGAQATFPQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSF 351
EEC C + GP NG +D++
Sbjct: 167 TLEECKNIC---EDGP------------------------------------NGFQVDNY 187
Query: 352 LECDDTPNCPDASDEAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNP 411
N + S K S F+ H PS C+ D GLC+ + R+YYN
Sbjct: 188 ---GTQLNAVNNSLTPQSTKVPSLFE----FHGPS---WCLTPADRGLCRANENRFYYNS 237
Query: 412 FSEHCARFTYGGCYGNKNNFEEEQQCLESCR 442
C F Y GC GN+NNF +Q+CL +C+
Sbjct: 238 VIGKCRPFKYSGCGGNENNFTSKQECLRACK 268
>gi|4502067 alpha-1-microglobulin/bikunin preproprotein [Homo
sapiens]
Length = 352
Score = 65.1 bits (157), Expect = 2e-10
Identities = 42/131 (32%), Positives = 56/131 (42%), Gaps = 10/131 (7%)
Query: 240 VLSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILA 299
V + ED C G C G R++Y+ T C++F YGGC+GN NN++ E+EC+
Sbjct: 221 VTEVTKKEDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQT 280
Query: 300 CRGVQGGPLRGSSGAQATFPQGPSMERRHPVC----SGTCQPTQFRCSNGCCIDSFLECD 355
CR V L G F Q + + C G CQ NG S EC
Sbjct: 281 CRTVAACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQ------GNGNKFYSEKECR 334
Query: 356 DTPNCPDASDE 366
+ P DE
Sbjct: 335 EYCGVPGDGDE 345
Score = 54.3 bits (129), Expect = 3e-07
Identities = 22/48 (45%), Positives = 30/48 (62%)
Query: 398 GLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCRGIS 445
G C R++YN S C F YGGC GN NNF E++CL++CR ++
Sbjct: 238 GPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRTVA 285
Score = 45.4 bits (106), Expect = 1e-04
Identities = 18/44 (40%), Positives = 23/44 (52%)
Query: 398 GLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESC 441
G C+ I W ++ C F YGGC GN N F E++C E C
Sbjct: 294 GPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYC 337
>gi|41406055 amyloid beta A4 protein isoform b precursor [Homo
sapiens]
Length = 751
Score = 64.3 bits (155), Expect = 3e-10
Identities = 33/100 (33%), Positives = 45/100 (45%), Gaps = 4/100 (4%)
Query: 233 TANVTVTVLSTKQTEDY----CLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKN 288
T+ T T +T+ E+ C + G CR RWY+D TE C F YGGC GN+N
Sbjct: 270 TSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRN 329
Query: 289 NYLREEECILACRGVQGGPLRGSSGAQATFPQGPSMERRH 328
N+ EE C+ C + A + + P E H
Sbjct: 330 NFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEH 369
Score = 60.1 bits (144), Expect = 5e-09
Identities = 23/51 (45%), Positives = 32/51 (62%)
Query: 391 CVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESC 441
C + +TG C+ I RWY++ CA F YGGC GN+NNF+ E+ C+ C
Sbjct: 291 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
>gi|4502167 amyloid beta A4 protein isoform a precursor [Homo
sapiens]
Length = 770
Score = 63.2 bits (152), Expect = 6e-10
Identities = 29/72 (40%), Positives = 38/72 (52%), Gaps = 4/72 (5%)
Query: 233 TANVTVTVLSTKQTEDY----CLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKN 288
T+ T T +T+ E+ C + G CR RWY+D TE C F YGGC GN+N
Sbjct: 270 TSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRN 329
Query: 289 NYLREEECILAC 300
N+ EE C+ C
Sbjct: 330 NFDTEEYCMAVC 341
Score = 60.5 bits (145), Expect = 4e-09
Identities = 26/79 (32%), Positives = 42/79 (53%), Gaps = 6/79 (7%)
Query: 391 CVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCRGISKKDVF 450
C + +TG C+ I RWY++ CA F YGGC GN+NNF+ E+ C+ C + +
Sbjct: 291 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLL 350
Query: 451 GLRRE------IPIPSTGS 463
+E + +P+T +
Sbjct: 351 KTTQEPLARDPVKLPTTAA 369
>gi|209915573 amyloid beta A4 protein isoform f precursor [Homo
sapiens]
Length = 714
Score = 63.2 bits (152), Expect = 6e-10
Identities = 29/72 (40%), Positives = 38/72 (52%), Gaps = 4/72 (5%)
Query: 233 TANVTVTVLSTKQTEDY----CLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKN 288
T+ T T +T+ E+ C + G CR RWY+D TE C F YGGC GN+N
Sbjct: 214 TSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRN 273
Query: 289 NYLREEECILAC 300
N+ EE C+ C
Sbjct: 274 NFDTEEYCMAVC 285
Score = 60.5 bits (145), Expect = 4e-09
Identities = 26/79 (32%), Positives = 42/79 (53%), Gaps = 6/79 (7%)
Query: 391 CVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCRGISKKDVF 450
C + +TG C+ I RWY++ CA F YGGC GN+NNF+ E+ C+ C + +
Sbjct: 235 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLL 294
Query: 451 GLRRE------IPIPSTGS 463
+E + +P+T +
Sbjct: 295 KTTQEPLARDPVKLPTTAA 313
>gi|214010181 amyloid beta (A4) precursor-like protein 2 isoform 2
[Homo sapiens]
Length = 751
Score = 62.4 bits (150), Expect = 1e-09
Identities = 25/57 (43%), Positives = 33/57 (57%)
Query: 388 KGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCRGI 444
K C TG C+ +PRWY++ C RF YGGC GN+NNFE E C+ C+ +
Sbjct: 307 KAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAM 363
Score = 60.5 bits (145), Expect = 4e-09
Identities = 35/114 (30%), Positives = 56/114 (49%), Gaps = 6/114 (5%)
Query: 196 TDVRVERKDPNQVELWGLKEGTYLFQLTVTSSDHPED--TANVTVTVLSTKQ-TEDY--- 249
T+ V+ D ++ E + E + T D+ E+ T + +S K+ T D
Sbjct: 250 TEAAVDEDDEDEEEGEEVVEDRDYYYDTFKGDDYNEENPTEPGSDGTMSDKEITHDVKAV 309
Query: 250 CLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGV 303
C G CR PRWY+D ++ C F+YGGC GN+NN+ E+ C+ C+ +
Sbjct: 310 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAM 363
>gi|4502147 amyloid beta (A4) precursor-like protein 2 isoform 1
[Homo sapiens]
Length = 763
Score = 62.4 bits (150), Expect = 1e-09
Identities = 25/57 (43%), Positives = 33/57 (57%)
Query: 388 KGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCRGI 444
K C TG C+ +PRWY++ C RF YGGC GN+NNFE E C+ C+ +
Sbjct: 307 KAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAM 363
Score = 60.5 bits (145), Expect = 4e-09
Identities = 35/114 (30%), Positives = 56/114 (49%), Gaps = 6/114 (5%)
Query: 196 TDVRVERKDPNQVELWGLKEGTYLFQLTVTSSDHPED--TANVTVTVLSTKQ-TEDY--- 249
T+ V+ D ++ E + E + T D+ E+ T + +S K+ T D
Sbjct: 250 TEAAVDEDDEDEEEGEEVVEDRDYYYDTFKGDDYNEENPTEPGSDGTMSDKEITHDVKAV 309
Query: 250 CLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGV 303
C G CR PRWY+D ++ C F+YGGC GN+NN+ E+ C+ C+ +
Sbjct: 310 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAM 363
>gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo
sapiens]
Length = 2971
Score = 60.8 bits (146), Expect = 3e-09
Identities = 23/52 (44%), Positives = 35/52 (67%)
Query: 396 DTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCRGISKK 447
D G C++ I +WYY+P ++ CARF YGGC GN+N F +++C + C + K
Sbjct: 2911 DEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLAK 2962
Score = 58.2 bits (139), Expect = 2e-08
Identities = 29/76 (38%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Query: 233 TANVTVTVLSTKQTE-DYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYL 291
T N+ V+ TE D C G CR +WYYDP + C F YGGC GN+N +
Sbjct: 2888 TINLMVSTEPLALTETDICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFG 2947
Query: 292 REEECILACRGVQGGP 307
++EC C V P
Sbjct: 2948 SQKECEKVCAPVLAKP 2963
>gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo
sapiens]
Length = 3177
Score = 60.8 bits (146), Expect = 3e-09
Identities = 23/52 (44%), Positives = 35/52 (67%)
Query: 396 DTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCRGISKK 447
D G C++ I +WYY+P ++ CARF YGGC GN+N F +++C + C + K
Sbjct: 3117 DEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLAK 3168
Score = 58.2 bits (139), Expect = 2e-08
Identities = 29/76 (38%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Query: 233 TANVTVTVLSTKQTE-DYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYL 291
T N+ V+ TE D C G CR +WYYDP + C F YGGC GN+N +
Sbjct: 3094 TINLMVSTEPLALTETDICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFG 3153
Query: 292 REEECILACRGVQGGP 307
++EC C V P
Sbjct: 3154 SQKECEKVCAPVLAKP 3169
>gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo
sapiens]
Length = 2570
Score = 60.8 bits (146), Expect = 3e-09
Identities = 23/52 (44%), Positives = 35/52 (67%)
Query: 396 DTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCRGISKK 447
D G C++ I +WYY+P ++ CARF YGGC GN+N F +++C + C + K
Sbjct: 2510 DEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLAK 2561
Score = 58.2 bits (139), Expect = 2e-08
Identities = 29/76 (38%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Query: 233 TANVTVTVLSTKQTE-DYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYL 291
T N+ V+ TE D C G CR +WYYDP + C F YGGC GN+N +
Sbjct: 2487 TINLMVSTEPLALTETDICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFG 2546
Query: 292 REEECILACRGVQGGP 307
++EC C V P
Sbjct: 2547 SQKECEKVCAPVLAKP 2562
>gi|145309328 papilin [Homo sapiens]
Length = 1251
Score = 60.1 bits (144), Expect = 5e-09
Identities = 27/65 (41%), Positives = 35/65 (53%)
Query: 250 CLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQGGPLR 309
CL + G C RWY+ + C F YGGC GN NN+ E+EC+ +C+G GP R
Sbjct: 727 CLLPSAHGSCADWAARWYFVASVGQCNRFWYGGCHGNANNFASEQECMSSCQGSLHGPRR 786
Query: 310 GSSGA 314
GA
Sbjct: 787 PQPGA 791
Score = 59.7 bits (143), Expect = 6e-09
Identities = 27/60 (45%), Positives = 34/60 (56%), Gaps = 4/60 (6%)
Query: 398 GLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCRGISKKDVFGLRREIP 457
G C + RWY+ C RF YGGC+GN NNF EQ+C+ SC+G + G RR P
Sbjct: 734 GSCADWAARWYFVASVGQCNRFWYGGCHGNANNFASEQECMSSCQG----SLHGPRRPQP 789
>gi|73760409 tissue factor pathway inhibitor isoform b precursor
[Homo sapiens]
Length = 251
Score = 59.7 bits (143), Expect = 6e-09
Identities = 27/75 (36%), Positives = 37/75 (49%)
Query: 232 DTANVTVTVLSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYL 291
D AN + ++ D+C G CRG R++Y+ + C+ F YGGCLGN NN+
Sbjct: 107 DNANRIIKTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFE 166
Query: 292 REEECILACRGVQGG 306
EEC C G
Sbjct: 167 TLEECKNICEDGPNG 181
Score = 57.0 bits (136), Expect = 4e-08
Identities = 22/46 (47%), Positives = 30/46 (65%)
Query: 396 DTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESC 441
D G+C+ I R++YN ++ C RF YGGC GN NNFE ++C C
Sbjct: 130 DPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNIC 175
Score = 54.7 bits (130), Expect = 2e-07
Identities = 21/51 (41%), Positives = 30/51 (58%)
Query: 391 CVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESC 441
C D G CK + R+++N F+ C F YGGC GN+N FE ++C + C
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMC 104
Score = 46.6 bits (109), Expect = 6e-05
Identities = 22/79 (27%), Positives = 35/79 (44%)
Query: 222 LTVTSSDHPEDTANVTVTVLSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYG 281
L S + E T + K +C G C+ R++++ + C+ F+YG
Sbjct: 26 LNADSEEDEEHTIITDTELPPLKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYG 85
Query: 282 GCLGNKNNYLREEECILAC 300
GC GN+N + EEC C
Sbjct: 86 GCEGNQNRFESLEECKKMC 104
>gi|16751923 WAP, follistatin/kazal, immunoglobulin, kunitz and
netrin domain containing 1 precursor [Homo sapiens]
Length = 548
Score = 58.9 bits (141), Expect = 1e-08
Identities = 29/62 (46%), Positives = 32/62 (51%)
Query: 248 DYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQGGP 307
D C+ G CRG PRW Y P Q C FVYGGC GN NN+ E C AC + P
Sbjct: 357 DACVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDACPVPRTPP 416
Query: 308 LR 309
R
Sbjct: 417 CR 418
Score = 55.1 bits (131), Expect = 2e-07
Identities = 26/76 (34%), Positives = 36/76 (47%), Gaps = 3/76 (3%)
Query: 369 CEKYTSGFDELQRIHFPSDKGH---CVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCY 425
C+ GF+ + +G CV G C+ PRW Y+P + C F YGGC
Sbjct: 334 CDGAARGFETYEACQQACARGPGDACVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCE 393
Query: 426 GNKNNFEEEQQCLESC 441
GN NNF + C ++C
Sbjct: 394 GNGNNFHSRESCEDAC 409
Score = 40.0 bits (92), Expect = 0.005
Identities = 31/113 (27%), Positives = 41/113 (36%), Gaps = 18/113 (15%)
Query: 266 WYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQG---------GPLRGSSGAQA 316
W+YDP C +F GC G + E C AC G GP R G +
Sbjct: 317 WHYDPQRGGCMTFPARGCDGAARGFETYEACQQACARGPGDACVLPAVQGPCR---GWEP 373
Query: 317 TFPQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAAC 369
+ P +++ HP G C+ NG S C+D P AC
Sbjct: 374 RWAYSPLLQQCHPFVYGGCE------GNGNNFHSRESCEDACPVPRTPPCRAC 420
Score = 33.9 bits (76), Expect = 0.38
Identities = 17/52 (32%), Positives = 23/52 (44%), Gaps = 4/52 (7%)
Query: 394 LPD----TGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESC 441
LPD TG + W+Y+P C F GC G FE + C ++C
Sbjct: 300 LPDVQACTGPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQAC 351
>gi|28212222 WFIKKN2 protein [Homo sapiens]
Length = 576
Score = 58.2 bits (139), Expect = 2e-08
Identities = 24/44 (54%), Positives = 26/44 (59%)
Query: 398 GLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESC 441
G CK PRW YN + C F YGGC GN NNFE + C ESC
Sbjct: 393 GPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESC 436
Score = 50.4 bits (119), Expect = 4e-06
Identities = 21/44 (47%), Positives = 26/44 (59%)
Query: 257 GRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILAC 300
G C+ PRW Y+ C+SFVYGGC GN NN+ E C +C
Sbjct: 393 GPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESC 436
Score = 48.9 bits (115), Expect = 1e-05
Identities = 20/58 (34%), Positives = 34/58 (58%), Gaps = 2/58 (3%)
Query: 384 FPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESC 441
FP+ C+ PD+ C E RW+++ + +C FT+G C+ N N+FE + C+ +C
Sbjct: 323 FPA--AECLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEACMLAC 378
Score = 44.7 bits (104), Expect = 2e-04
Identities = 28/92 (30%), Positives = 36/92 (39%), Gaps = 13/92 (14%)
Query: 221 QLTVTSSDHPEDTANVTVTVLSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVY 280
Q TS P TA L +ED C RW++D C +F +
Sbjct: 309 QAAATSESSPNGTAFPAAECLKPPDSED----------CGEEQTRWHFDAQANNCLTFTF 358
Query: 281 GGCLGNKNNYLREEECILACRGVQGGPLRGSS 312
G C N N++ E C+LAC GPL S
Sbjct: 359 GHCHRNLNHFETYEACMLAC---MSGPLAACS 387
>gi|31563528 serine peptidase inhibitor-like, with Kunitz and WAP
domains 1 isoform 2 [Homo sapiens]
Length = 117
Score = 57.0 bits (136), Expect = 4e-08
Identities = 21/55 (38%), Positives = 29/55 (52%)
Query: 247 EDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACR 301
+D C + G C F W+YD + C FVYGGC GN NN+ + C+ C+
Sbjct: 58 QDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTCK 112
Score = 52.8 bits (125), Expect = 8e-07
Identities = 19/47 (40%), Positives = 27/47 (57%)
Query: 396 DTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCR 442
+TG C W+Y+ C+ F YGGC GN NNF+ + CL +C+
Sbjct: 66 ETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTCK 112
>gi|10732863 serine peptidase inhibitor-like, with Kunitz and WAP
domains 1 isoform 1 precursor [Homo sapiens]
Length = 133
Score = 57.0 bits (136), Expect = 4e-08
Identities = 21/55 (38%), Positives = 29/55 (52%)
Query: 247 EDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACR 301
+D C + G C F W+YD + C FVYGGC GN NN+ + C+ C+
Sbjct: 74 QDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTCK 128
Score = 52.8 bits (125), Expect = 8e-07
Identities = 19/47 (40%), Positives = 27/47 (57%)
Query: 396 DTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCR 442
+TG C W+Y+ C+ F YGGC GN NNF+ + CL +C+
Sbjct: 82 ETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTCK 128
>gi|154759255 collagen, type XXVIII precursor [Homo sapiens]
Length = 1125
Score = 54.3 bits (129), Expect = 3e-07
Identities = 21/51 (41%), Positives = 30/51 (58%)
Query: 391 CVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESC 441
C++ G C E + RWYY+ CARF + GC G+ N F E++C E+C
Sbjct: 1072 CLEALKPGNCGEYVVRWYYDKQVNSCARFWFSGCNGSGNRFNSEKECQETC 1122
Score = 49.3 bits (116), Expect = 9e-06
Identities = 28/91 (30%), Positives = 39/91 (42%), Gaps = 2/91 (2%)
Query: 215 EGTYLFQLTVTSSDHPEDTANVTVTVLSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQI 274
E T+ L T+S T ++ + CL + K G C RWYYD
Sbjct: 1037 EPTWADDLPATTSSEATTTPRPLLSTPVDGAEDPRCLEALKPGNCGEYVVRWYYDKQVNS 1096
Query: 275 CKSFVYGGCLGNKNNYLREEECILACRGVQG 305
C F + GC G+ N + E+EC C +QG
Sbjct: 1097 CARFWFSGCNGSGNRFNSEKECQETC--IQG 1125
>gi|4507157 sortilin-related receptor containing LDLR class A repeats
preproprotein [Homo sapiens]
Length = 2214
Score = 50.8 bits (120), Expect = 3e-06
Identities = 37/124 (29%), Positives = 51/124 (41%), Gaps = 16/124 (12%)
Query: 272 EQICKSFVYGGCLGNKNNYLREEECI---LACRGVQGGPLRGSSGAQATFPQGPSMERRH 328
E +C F+ C KN ++C+ + C G+ R S A F H
Sbjct: 1272 EPLCTHFMDFVC---KNR----QQCLFHSMVCDGII--QCRDGSDEDAAFAGCSQDPEFH 1322
Query: 329 PVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGFDELQRIHFPSDK 388
VC F+C NG CI +CD +C D SDEA CE T + + F +
Sbjct: 1323 KVCD----EFGFQCQNGVCISLIWKCDGMDDCGDYSDEANCENPTEAPNCSRYFQFRCEN 1378
Query: 389 GHCV 392
GHC+
Sbjct: 1379 GHCI 1382
Score = 50.4 bits (119), Expect = 4e-06
Identities = 35/107 (32%), Positives = 43/107 (40%), Gaps = 16/107 (14%)
Query: 334 TCQPTQFRCSNGCCIDSFLECDDTPNCPDASDE--AACEKYTSGFDELQRIHFPSDKGHC 391
TC+ + F+C NG CI CD +C D SDE CEK +GF PS K HC
Sbjct: 1198 TCEASNFQCRNGHCIPQRWACDGDTDCQDGSDEDPVNCEKKCNGFRCPNGTCIPSSK-HC 1256
Query: 392 VDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCL 438
L D C + + P H F + QQCL
Sbjct: 1257 DGLRD---CSDGSDEQHCEPLCTHFMDFV----------CKNRQQCL 1290
Score = 45.8 bits (107), Expect = 1e-04
Identities = 28/77 (36%), Positives = 35/77 (45%), Gaps = 4/77 (5%)
Query: 319 PQGPSMERRHPVCS-GTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGFD 377
PQG ++ V TC Q+RCSNG CI+S CD +C D SDE C D
Sbjct: 1061 PQGYQLKNNTCVKEENTCLRNQYRCSNGNCINSIWWCDFDNDCGDMSDERNCPTTICDLD 1120
Query: 378 ELQRIHFPSDKGHCVDL 394
R + G C+ L
Sbjct: 1121 TQFRC---QESGTCIPL 1134
Score = 45.1 bits (105), Expect = 2e-04
Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 3/58 (5%)
Query: 335 CQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGFDELQRIHFPSDKGHCV 392
C+ ++ CS+G CI S CD +C D SDEA C T+ + + +F GHC+
Sbjct: 1158 CRSDEYNCSSGMCIRSSWVCDGDNDCRDWSDEANC---TAIYHTCEASNFQCRNGHCI 1212
Score = 43.1 bits (100), Expect = 6e-04
Identities = 17/36 (47%), Positives = 21/36 (58%)
Query: 334 TCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAAC 369
TC P +RCS+G C+ CD +C D SDE AC
Sbjct: 1418 TCLPNYYRCSSGTCVMDTWVCDGYRDCADGSDEEAC 1453
Score = 38.1 bits (87), Expect = 0.020
Identities = 19/42 (45%), Positives = 24/42 (57%), Gaps = 1/42 (2%)
Query: 338 TQFRCS-NGCCIDSFLECDDTPNCPDASDEAACEKYTSGFDE 378
TQFRC +G CI +CD +C D SDE+ CE + DE
Sbjct: 1121 TQFRCQESGTCIPLSYKCDLEDDCGDNSDESHCEMHQCRSDE 1162
Score = 37.4 bits (85), Expect = 0.034
Identities = 16/31 (51%), Positives = 19/31 (61%)
Query: 339 QFRCSNGCCIDSFLECDDTPNCPDASDEAAC 369
QFRC NG CI + +CD +C D SDE C
Sbjct: 1373 QFRCENGHCIPNRWKCDRENDCGDWSDEKDC 1403
Score = 35.0 bits (79), Expect = 0.17
Identities = 18/55 (32%), Positives = 29/55 (52%), Gaps = 2/55 (3%)
Query: 334 TCQPTQFRCSNG-CCIDSFLECDDTPNCPDASDEAACEKYTSGFDELQRIHFPSD 387
TC +F+C +G CI CD +C D SDE AC + + ++Q + + +D
Sbjct: 1513 TCMSREFQCEDGEACIVLSERCDGFLDCSDESDEKACSDELTVY-KVQNLQWTAD 1566
Score = 33.1 bits (74), Expect = 0.64
Identities = 15/47 (31%), Positives = 22/47 (46%), Gaps = 1/47 (2%)
Query: 329 PVCSGTCQPTQFRCSNG-CCIDSFLECDDTPNCPDASDEAACEKYTS 374
P G C +F C CI ++ CD +C D DEA C +++
Sbjct: 1465 PTQLGRCDRFEFECHQPKTCIPNWKRCDGHQDCQDGRDEANCPTHST 1511
>gi|65301164 very low density lipoprotein receptor isoform b [Homo
sapiens]
Length = 845
Score = 49.7 bits (117), Expect = 7e-06
Identities = 23/58 (39%), Positives = 31/58 (53%), Gaps = 5/58 (8%)
Query: 335 CQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGFDELQRIHFPSDKGHCV 392
C+P+QF+C+NG CI +CD +C D SDE C K T + F + G CV
Sbjct: 33 CEPSQFQCTNGRCITLLWKCDGDEDCVDGSDEKNCVKKTCAESD-----FVCNNGQCV 85
Score = 47.8 bits (112), Expect = 3e-05
Identities = 25/83 (30%), Positives = 35/83 (42%), Gaps = 3/83 (3%)
Query: 332 SGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGFDELQRIHFPSDKGHC 391
S TC+P QF C +G CI +C+ +C D SDE C+ L F G C
Sbjct: 275 SRTCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDEVNCKNVNQC---LGPGKFKCRSGEC 331
Query: 392 VDLPDTGLCKESIPRWYYNPFSE 414
+D+ ++ W P E
Sbjct: 332 IDISKVCNQEQDCRDWSDEPLKE 354
Score = 45.8 bits (107), Expect = 1e-04
Identities = 22/66 (33%), Positives = 30/66 (45%), Gaps = 5/66 (7%)
Query: 327 RHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGFDELQRIHFPS 386
R PV C ++ +C +G CI CD P+C D SDE C T D+ F
Sbjct: 231 RQPVIHTKCPASEIQCGSGECIHKKWRCDGDPDCKDGSDEVNCPSRTCRPDQ-----FEC 285
Query: 387 DKGHCV 392
+ G C+
Sbjct: 286 EDGSCI 291
Score = 45.4 bits (106), Expect = 1e-04
Identities = 20/47 (42%), Positives = 24/47 (51%)
Query: 334 TCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGFDELQ 380
TC P +F CS+G CI C+ +C D SDE C T G E Q
Sbjct: 153 TCSPDEFTCSSGRCISRNFVCNGQDDCSDGSDELDCAPPTCGAHEFQ 199
Score = 42.0 bits (97), Expect = 0.001
Identities = 16/34 (47%), Positives = 22/34 (64%)
Query: 334 TCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEA 367
TC + F C+NG C+ S +CD P+C D SDE+
Sbjct: 71 TCAESDFVCNNGQCVPSRWKCDGDPDCEDGSDES 104
Score = 36.6 bits (83), Expect = 0.058
Identities = 15/34 (44%), Positives = 19/34 (55%)
Query: 334 TCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEA 367
TC +F+CS CI CDD +C D SDE+
Sbjct: 192 TCGAHEFQCSTSSCIPISWVCDDDADCSDQSDES 225
>gi|65301167 very low density lipoprotein receptor isoform a [Homo
sapiens]
Length = 873
Score = 49.7 bits (117), Expect = 7e-06
Identities = 23/58 (39%), Positives = 31/58 (53%), Gaps = 5/58 (8%)
Query: 335 CQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGFDELQRIHFPSDKGHCV 392
C+P+QF+C+NG CI +CD +C D SDE C K T + F + G CV
Sbjct: 33 CEPSQFQCTNGRCITLLWKCDGDEDCVDGSDEKNCVKKTCAESD-----FVCNNGQCV 85
Score = 47.8 bits (112), Expect = 3e-05
Identities = 25/83 (30%), Positives = 35/83 (42%), Gaps = 3/83 (3%)
Query: 332 SGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGFDELQRIHFPSDKGHC 391
S TC+P QF C +G CI +C+ +C D SDE C+ L F G C
Sbjct: 275 SRTCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDEVNCKNVNQC---LGPGKFKCRSGEC 331
Query: 392 VDLPDTGLCKESIPRWYYNPFSE 414
+D+ ++ W P E
Sbjct: 332 IDISKVCNQEQDCRDWSDEPLKE 354
Score = 45.8 bits (107), Expect = 1e-04
Identities = 22/66 (33%), Positives = 30/66 (45%), Gaps = 5/66 (7%)
Query: 327 RHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGFDELQRIHFPS 386
R PV C ++ +C +G CI CD P+C D SDE C T D+ F
Sbjct: 231 RQPVIHTKCPASEIQCGSGECIHKKWRCDGDPDCKDGSDEVNCPSRTCRPDQ-----FEC 285
Query: 387 DKGHCV 392
+ G C+
Sbjct: 286 EDGSCI 291
Score = 45.4 bits (106), Expect = 1e-04
Identities = 20/47 (42%), Positives = 24/47 (51%)
Query: 334 TCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGFDELQ 380
TC P +F CS+G CI C+ +C D SDE C T G E Q
Sbjct: 153 TCSPDEFTCSSGRCISRNFVCNGQDDCSDGSDELDCAPPTCGAHEFQ 199
Score = 42.0 bits (97), Expect = 0.001
Identities = 16/34 (47%), Positives = 22/34 (64%)
Query: 334 TCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEA 367
TC + F C+NG C+ S +CD P+C D SDE+
Sbjct: 71 TCAESDFVCNNGQCVPSRWKCDGDPDCEDGSDES 104
Score = 36.6 bits (83), Expect = 0.058
Identities = 15/34 (44%), Positives = 19/34 (55%)
Query: 334 TCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEA 367
TC +F+CS CI CDD +C D SDE+
Sbjct: 192 TCGAHEFQCSTSSCIPISWVCDDDADCSDQSDES 225
>gi|189571689 serine protease inhibitor, Kunitz type, 3 [Homo
sapiens]
Length = 89
Score = 49.7 bits (117), Expect = 7e-06
Identities = 20/52 (38%), Positives = 30/52 (57%)
Query: 250 CLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACR 301
C + G C+ RW+++ C+ F YGGC GN NN+LR+E+C C+
Sbjct: 36 CAFPMEKGPCQTYMTRWFFNFETGECELFAYGGCGGNSNNFLRKEKCEKFCK 87
Score = 49.3 bits (116), Expect = 9e-06
Identities = 19/52 (36%), Positives = 30/52 (57%)
Query: 391 CVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCR 442
C + G C+ + RW++N + C F YGGC GN NNF +++C + C+
Sbjct: 36 CAFPMEKGPCQTYMTRWFFNFETGECELFAYGGCGGNSNNFLRKEKCEKFCK 87
>gi|153946389 WAP four-disulfide core domain 8 precursor [Homo
sapiens]
Length = 241
Score = 49.3 bits (116), Expect = 9e-06
Identities = 20/54 (37%), Positives = 28/54 (51%)
Query: 247 EDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILAC 300
++ C+ + G C RW++D C F Y GC GN NN+L E+ C AC
Sbjct: 92 QEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTAC 145
Score = 45.1 bits (105), Expect = 2e-04
Identities = 34/111 (30%), Positives = 48/111 (43%), Gaps = 18/111 (16%)
Query: 345 GCCIDSFLECDDTPNCPDASD-EAACEKYTSGFDELQRIHFPSDKGHCVD-------LPD 396
G C L C T PD+ + + C++Y Q+ F + + C+D LP
Sbjct: 49 GLCPKERLTC--TTELPDSCNTDFDCKEY-------QKCCFFACQKKCMDPFQEPCMLPV 99
Query: 397 T-GLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCRGISK 446
G C RW+++ + C F Y GC GN NNF E C +C I K
Sbjct: 100 RHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTACMLIVK 150
>gi|153946387 WAP four-disulfide core domain 8 precursor [Homo
sapiens]
Length = 241
Score = 49.3 bits (116), Expect = 9e-06
Identities = 20/54 (37%), Positives = 28/54 (51%)
Query: 247 EDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILAC 300
++ C+ + G C RW++D C F Y GC GN NN+L E+ C AC
Sbjct: 92 QEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTAC 145
Score = 45.1 bits (105), Expect = 2e-04
Identities = 34/111 (30%), Positives = 48/111 (43%), Gaps = 18/111 (16%)
Query: 345 GCCIDSFLECDDTPNCPDASD-EAACEKYTSGFDELQRIHFPSDKGHCVD-------LPD 396
G C L C T PD+ + + C++Y Q+ F + + C+D LP
Sbjct: 49 GLCPKERLTC--TTELPDSCNTDFDCKEY-------QKCCFFACQKKCMDPFQEPCMLPV 99
Query: 397 T-GLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCRGISK 446
G C RW+++ + C F Y GC GN NNF E C +C I K
Sbjct: 100 RHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTACMLIVK 150
>gi|119709832 low density lipoprotein receptor-related protein 5 [Homo
sapiens]
Length = 1615
Score = 48.9 bits (115), Expect = 1e-05
Identities = 19/40 (47%), Positives = 24/40 (60%)
Query: 331 CSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACE 370
C C P QFRC++G C+ +CD P+C D SDE CE
Sbjct: 1332 CDAICLPNQFRCASGQCVLIKQQCDSFPDCIDGSDELMCE 1371
Score = 48.1 bits (113), Expect = 2e-05
Identities = 25/63 (39%), Positives = 29/63 (46%), Gaps = 9/63 (14%)
Query: 334 TCQPTQFRCSNG--CCIDSFLECDDTPNCPDASDEAACEKYTSGFDELQRIHFPSDKGHC 391
TC P QF C+ G CI CD P C D SDE C ++ FP +G C
Sbjct: 1258 TCSPDQFACATGEIDCIPGAWRCDGFPECDDQSDEEGCPVCSAA-------QFPCARGQC 1310
Query: 392 VDL 394
VDL
Sbjct: 1311 VDL 1313
Score = 44.3 bits (103), Expect = 3e-04
Identities = 22/48 (45%), Positives = 26/48 (54%), Gaps = 4/48 (8%)
Query: 323 SMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACE 370
S E PVCS QF C+ G C+D L CD +C D SDEA C+
Sbjct: 1290 SDEEGCPVCSAA----QFPCARGQCVDLRLRCDGEADCQDRSDEADCD 1333
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.138 0.449
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,918,779
Number of Sequences: 37866
Number of extensions: 1316428
Number of successful extensions: 5406
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 84
Number of HSP's successfully gapped in prelim test: 38
Number of HSP's that attempted gapping in prelim test: 4941
Number of HSP's gapped (non-prelim): 452
length of query: 529
length of database: 18,247,518
effective HSP length: 107
effective length of query: 422
effective length of database: 14,195,856
effective search space: 5990651232
effective search space used: 5990651232
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.