Guide to the Human Genome
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Search of human proteins with 32171205

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|32171205 EF-hand domain family, member A2 [Homo sapiens]
         (530 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|32171205 EF-hand domain family, member A2 [Homo sapiens]          1068   0.0  
gi|22749443 EF-hand domain family, member A1 [Homo sapiens]           281   8e-76
gi|116256483 calcium binding atopy-related autoantigen 1 [Homo s...   147   3e-35
gi|21361103 solute carrier family 25, member 12 [Homo sapiens]         47   4e-05
gi|20149640 dual oxidase 1 precursor [Homo sapiens]                    42   0.001
gi|28872751 dual oxidase 1 precursor [Homo sapiens]                    42   0.001
gi|4757974 centrin 1 [Homo sapiens]                                    40   0.007
gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo s...    39   0.009
gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo...    39   0.009
gi|4757902 caltractin [Homo sapiens]                                   37   0.045
gi|46397403 centrin 3 [Homo sapiens]                                   37   0.045
gi|22212896 protein phosphatase 3 regulatory subunit B, beta iso...    37   0.058
gi|132566532 dual oxidase 2 precursor [Homo sapiens]                   35   0.22 
gi|98985795 neurocalcin delta [Homo sapiens]                           35   0.22 
gi|98985793 neurocalcin delta [Homo sapiens]                           35   0.22 
gi|98985791 neurocalcin delta [Homo sapiens]                           35   0.22 
gi|98985789 neurocalcin delta [Homo sapiens]                           35   0.22 
gi|98985787 neurocalcin delta [Homo sapiens]                           35   0.22 
gi|98985785 neurocalcin delta [Homo sapiens]                           35   0.22 
gi|98985783 neurocalcin delta [Homo sapiens]                           35   0.22 
gi|98985778 neurocalcin delta [Homo sapiens]                           35   0.22 
gi|19913446 hippocalcin [Homo sapiens]                                 34   0.29 
gi|4506025 protein phosphatase 3, regulatory subunit B, alpha is...    34   0.38 
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa...    34   0.38 
gi|19913443 hippocalcin-like 1 [Homo sapiens]                          34   0.38 
gi|19913441 hippocalcin-like 1 [Homo sapiens]                          34   0.38 
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap...    33   0.49 
gi|23065526 growth arrest-specific 2 like 1 isoform a [Homo sapi...    33   0.84 
gi|19923777 growth arrest-specific 2 like 1 isoform a [Homo sapi...    33   0.84 
gi|40254415 guanylate cyclase activator 1A (retina) [Homo sapiens]     32   1.1  

>gi|32171205 EF-hand domain family, member A2 [Homo sapiens]
          Length = 530

 Score = 1068 bits (2763), Expect = 0.0
 Identities = 530/530 (100%), Positives = 530/530 (100%)

Query: 1   MAALRRLLWPPPRVSPPLCAHQPLLGPWGRPAVTTLGLPGRPFSSREDEERAVAEAAWRR 60
           MAALRRLLWPPPRVSPPLCAHQPLLGPWGRPAVTTLGLPGRPFSSREDEERAVAEAAWRR
Sbjct: 1   MAALRRLLWPPPRVSPPLCAHQPLLGPWGRPAVTTLGLPGRPFSSREDEERAVAEAAWRR 60

Query: 61  RRRWGELSVAAAAGGGLVGLVCYQLYGDPRAGSPATGRPSKSAATEPEDPPRGRGMLPIP 120
           RRRWGELSVAAAAGGGLVGLVCYQLYGDPRAGSPATGRPSKSAATEPEDPPRGRGMLPIP
Sbjct: 61  RRRWGELSVAAAAGGGLVGLVCYQLYGDPRAGSPATGRPSKSAATEPEDPPRGRGMLPIP 120

Query: 121 VAAAKETVAIGRTDIEDLDLYATSRERRFRLFASIECEGQLFMTPYDFILAVTTDEPKVA 180
           VAAAKETVAIGRTDIEDLDLYATSRERRFRLFASIECEGQLFMTPYDFILAVTTDEPKVA
Sbjct: 121 VAAAKETVAIGRTDIEDLDLYATSRERRFRLFASIECEGQLFMTPYDFILAVTTDEPKVA 180

Query: 181 KTWKSLSKQELNQMLAETPPVWKGSSKLFRNLKEKGVISYTEYLFLLCILTKPHAGFRIA 240
           KTWKSLSKQELNQMLAETPPVWKGSSKLFRNLKEKGVISYTEYLFLLCILTKPHAGFRIA
Sbjct: 181 KTWKSLSKQELNQMLAETPPVWKGSSKLFRNLKEKGVISYTEYLFLLCILTKPHAGFRIA 240

Query: 241 FNMFDTDGNEMVDKKEFLVLQEIFRKKNEKREIKGDEEKRAMLRLQLYGYHSPTNSVLKT 300
           FNMFDTDGNEMVDKKEFLVLQEIFRKKNEKREIKGDEEKRAMLRLQLYGYHSPTNSVLKT
Sbjct: 241 FNMFDTDGNEMVDKKEFLVLQEIFRKKNEKREIKGDEEKRAMLRLQLYGYHSPTNSVLKT 300

Query: 301 DAEELVSRSYWDTLRRNTSQALFSDLAERADDITSLVTDTTLLVHFFGKKGKAELNFEDF 360
           DAEELVSRSYWDTLRRNTSQALFSDLAERADDITSLVTDTTLLVHFFGKKGKAELNFEDF
Sbjct: 301 DAEELVSRSYWDTLRRNTSQALFSDLAERADDITSLVTDTTLLVHFFGKKGKAELNFEDF 360

Query: 361 YRFMDNLQTEVLEIEFLSYSNGMNTISEEDFAHILLRYTNVENTSVFLENVRYSIPEEKG 420
           YRFMDNLQTEVLEIEFLSYSNGMNTISEEDFAHILLRYTNVENTSVFLENVRYSIPEEKG
Sbjct: 361 YRFMDNLQTEVLEIEFLSYSNGMNTISEEDFAHILLRYTNVENTSVFLENVRYSIPEEKG 420

Query: 421 ITFDEFRSFFQFLNNLEDFAIALNMYNFASRSIGQDEFKRAVYVATGLKFSPHLVNTVFK 480
           ITFDEFRSFFQFLNNLEDFAIALNMYNFASRSIGQDEFKRAVYVATGLKFSPHLVNTVFK
Sbjct: 421 ITFDEFRSFFQFLNNLEDFAIALNMYNFASRSIGQDEFKRAVYVATGLKFSPHLVNTVFK 480

Query: 481 IFDVDKDDQLSYKEFIGIMKDRLHRGFRGYKTVQKYPTFKSCLKKELHSR 530
           IFDVDKDDQLSYKEFIGIMKDRLHRGFRGYKTVQKYPTFKSCLKKELHSR
Sbjct: 481 IFDVDKDDQLSYKEFIGIMKDRLHRGFRGYKTVQKYPTFKSCLKKELHSR 530


>gi|22749443 EF-hand domain family, member A1 [Homo sapiens]
          Length = 434

 Score =  281 bits (720), Expect = 8e-76
 Identities = 153/384 (39%), Positives = 240/384 (62%), Gaps = 54/384 (14%)

Query: 145 RERRFRLFASIECEGQLFMTPYDFILAVTTDEPKVAKTWKSLSKQELNQMLAETPPVWKG 204
           R++RF  F+S+E EG+ +MTP DF+ +V  ++ +   + K L+K+++   L+       G
Sbjct: 86  RKQRFMQFSSLEHEGEYYMTPRDFLFSVMFEQMERKTSVKKLTKKDIEDTLSGIQTAGCG 145

Query: 205 SSKLFRNLKEKGVISYTEYLFLLCILTKPHAGFRIAFNMFDTDGNEMVDKKEFLVLQEIF 264
           S+  FR+L +KG+ISYTEYLFLL ILTKPH+GF +AF M DTDGNEM++K+EF  LQ+I 
Sbjct: 146 ST-FFRDLGDKGLISYTEYLFLLTILTKPHSGFHVAFKMLDTDGNEMIEKREFFKLQKII 204

Query: 265 RKKNEKREIKGDEEKRAMLRLQLYGYHSPTNSVLKTDAEELVSRSYWDTLRRNTSQALFS 324
            K+++   +K                                           T++  + 
Sbjct: 205 SKQDDLMTVK-------------------------------------------TNETGYQ 221

Query: 325 DLAERADDITSLVTDTTLLVHFFGKKGKAELNFEDFYRFMDNLQTEVLEIEFLSYSNGMN 384
           +   +  +I     +TTL + FFGK+G+ +L++++F RFM+NLQTE+ E+EFL +S G++
Sbjct: 222 EAIVKEPEI-----NTTLQMRFFGKRGQRKLHYKEFRRFMENLQTEIQEMEFLQFSKGLS 276

Query: 385 TISEEDFAHILLRYTNVENTSVFLENVRYSIPEEKGITFDEFRSFFQFLNNLEDFAIALN 444
            + +EDFA  LL +TN EN  ++ +NVR  +   + I+ DEF+SF  F  +LEDFAIA+ 
Sbjct: 277 FMRKEDFAEWLLFFTNTENKDIYWKNVREKLSAGESISLDEFKSFCHFTTHLEDFAIAMQ 336

Query: 445 MYNFASRSIGQDEFKRAVYVATGLKFSPHLVNTVFKIFDVDKDDQLSYKEFIGIMKDRLH 504
           M++ A R +   EFKRAV VATG + S ++++TVFKIFD+D D+ LS++EF+G++K+R+H
Sbjct: 337 MFSLAHRPVRLAEFKRAVKVATGQELSNNILDTVFKIFDLDGDECLSHEEFLGVLKNRMH 396

Query: 505 RGF--RGYKTVQKYPTFKSCLKKE 526
           RG     ++++Q+Y     C+KKE
Sbjct: 397 RGLWVPQHQSIQEY---WKCVKKE 417


>gi|116256483 calcium binding atopy-related autoantigen 1 [Homo
           sapiens]
          Length = 478

 Score =  147 bits (370), Expect = 3e-35
 Identities = 105/374 (28%), Positives = 170/374 (45%), Gaps = 65/374 (17%)

Query: 146 ERRFRLFASIEC-----EGQLFMTPYDFILAVTTDEPKVAKTWKSLSKQELNQMLAETPP 200
           ++ FR FA+++      E ++FMTP DF+ ++T +E +       L +  + +   +T  
Sbjct: 125 DKIFRYFATLKVISEPGEAEVFMTPEDFVRSITPNEKQPEHL--GLDQYIIKRFDGKTEK 182

Query: 201 VWKGSSK------LFRNLKEKGVISYTEYLFLLCILTKPHAGFRIAFNMFDTDGNEMVDK 254
           + +   K      +F  L E G+IS+++Y+FL  +L+ P   F IAF MFD +G+  VD 
Sbjct: 183 ISQEREKFADEGSIFYTLGECGLISFSDYIFLTTVLSTPQRNFEIAFKMFDLNGDGEVDM 242

Query: 255 KEFLVLQEIFRKKNEKREIKGDEEKRAMLRLQLYGYHSPTNSVLKTDAEELVSRSYWDTL 314
           +EF  +Q I R +        D                                      
Sbjct: 243 EEFEQVQSIIRSQTSMGMRHRD-------------------------------------- 264

Query: 315 RRNTSQALFSDLAERADDITSLVTDTTLLVHFFGKKGKAELNFEDFYRFMDNLQTEVLEI 374
           R  T   L S L             + L  +FFG   K +L  ++F  F   LQ +VL++
Sbjct: 265 RPTTGNTLKSGLC------------SALTTYFFGADLKGKLTIKNFLEFQRKLQHDVLKL 312

Query: 375 EFLSYSNGMNTISEEDFAHILLRYTNVENTSV--FLENVRYSIPEEKGITFDEFRSFFQF 432
           EF  +      I+E  F  +LL Y+ V++  +      ++    E KG+TF E  +FF F
Sbjct: 313 EFERHDPVDGRITERQFGGMLLAYSGVQSKKLTAMQRQLKKHFKEGKGLTFQEVENFFTF 372

Query: 433 LNNLEDFAIALNMYNFASRSIGQDEFKRAVYVATGLKFSPHLVNTVFKIFDVDKDDQLSY 492
           L N+ D   AL+ Y+ A  S+ +   ++       ++ S H+ + VF +FD D + +LS 
Sbjct: 373 LKNINDVDTALSFYHMAGASLDKVTMQQVARTVAKVELSDHVCDVVFALFDCDGNGELSN 432

Query: 493 KEFIGIMKDRLHRG 506
           KEF+ IMK RL RG
Sbjct: 433 KEFVSIMKQRLMRG 446


>gi|21361103 solute carrier family 25, member 12 [Homo sapiens]
          Length = 678

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 72/297 (24%), Positives = 109/297 (36%), Gaps = 94/297 (31%)

Query: 149 FRLFASIECEGQLFMTPYDFI---LAVTTDEPKVAKTWKSLSKQELNQMLAETPPVWKGS 205
           F  +AS E +G+ +MTP DF+   L +  D           S  ++ Q+LA      K  
Sbjct: 20  FLQYASTEVDGERYMTPEDFVQRYLGLYNDPN---------SNPKIVQLLAGVADQTKD- 69

Query: 206 SKLFRNLKEKGVISYTEYLFLLCILTKPHAGFRIAFNMFDTDGNEMVDKKEFLVLQEIFR 265
                     G+ISY E+L    +L  P + F +AF +FD  GN  V    F  ++EIF 
Sbjct: 70  ----------GLISYQEFLAFESVLCAPDSMFIVAFQLFDKSGNGEV---TFENVKEIFG 116

Query: 266 KKNEKREIKGDEEKRAMLRLQLYGYHSPTNSVLKTDAEELVSRSYWDTLRRNTSQALFSD 325
           +                    +  +H P N               WD             
Sbjct: 117 Q-------------------TIIHHHIPFN---------------WDC------------ 130

Query: 326 LAERADDITSLVTDTTLLVHFFGKKGKAELNFEDFYRFMDNLQTEVLEIEF-LSYSNGMN 384
                           + +HF G   K  LN+ +F +F+  LQ E     F L   +   
Sbjct: 131 --------------EFIRLHF-GHNRKKHLNYTEFTQFLQELQLEHARQAFALKDKSKSG 175

Query: 385 TISEEDFAHILLRYTNVENTSVFLENV----RYSIPEEKGITFDEFRSFFQFLNNLE 437
            IS  DF+ I++   +   T    EN+      SI  +  ++F  F +F   LNN+E
Sbjct: 176 MISGLDFSDIMVTIRSHMLTPFVEENLVSAAGGSISHQ--VSFSYFNAFNSLLNNME 230


>gi|20149640 dual oxidase 1 precursor [Homo sapiens]
          Length = 1551

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 30/126 (23%), Positives = 55/126 (43%), Gaps = 11/126 (8%)

Query: 216 GVISYTEYLFLLCILTK--PHAGFRIAFNMFDTDGNEMVDKKEFLVLQEIFRKKNEKREI 273
           G +S+ E+L +L +  K  P    R+ F M+D DGN ++ K EF+ +   F + +     
Sbjct: 833 GYLSFREFLDILVVFMKGSPEEKSRLMFRMYDFDGNGLISKDEFIRMLRSFIEISNNCLS 892

Query: 274 KGDEEKRAMLRLQLYGYHSPTNSVLKTDAEELVSRSYWDTLRRNTSQALFSDLAERADDI 333
           K    +      +  G+          D EEL    +   LR + S+  F+ L  +  ++
Sbjct: 893 KAQLAEVVESMFRESGFQ---------DKEELTWEDFHFMLRDHNSELRFTQLCVKGVEV 943

Query: 334 TSLVTD 339
             ++ D
Sbjct: 944 PEVIKD 949



 Score = 35.8 bits (81), Expect = 0.100
 Identities = 30/131 (22%), Positives = 62/131 (47%), Gaps = 23/131 (17%)

Query: 241 FNMFDTDGNEMVDKKEFLVLQEIFRKKNEKREIKGDEEKRAMLRLQLYGYHSPTNSVLKT 300
           F++ D DGN  +  +EFL +  +F        +KG  E+++ L  ++Y +    N ++  
Sbjct: 824 FSLADKDGNGYLSFREFLDILVVF--------MKGSPEEKSRLMFRMYDFDG--NGLISK 873

Query: 301 DAEELVSRSYWDTLRRNTSQALFSDLAERADDITSLVTDTTLLVHFFGKKGKAELNFEDF 360
           D    + RS+ +      S+A  +++ E      S+  ++       G + K EL +EDF
Sbjct: 874 DEFIRMLRSFIEISNNCLSKAQLAEVVE------SMFRES-------GFQDKEELTWEDF 920

Query: 361 YRFMDNLQTEV 371
           +  + +  +E+
Sbjct: 921 HFMLRDHNSEL 931


>gi|28872751 dual oxidase 1 precursor [Homo sapiens]
          Length = 1551

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 30/126 (23%), Positives = 55/126 (43%), Gaps = 11/126 (8%)

Query: 216 GVISYTEYLFLLCILTK--PHAGFRIAFNMFDTDGNEMVDKKEFLVLQEIFRKKNEKREI 273
           G +S+ E+L +L +  K  P    R+ F M+D DGN ++ K EF+ +   F + +     
Sbjct: 833 GYLSFREFLDILVVFMKGSPEEKSRLMFRMYDFDGNGLISKDEFIRMLRSFIEISNNCLS 892

Query: 274 KGDEEKRAMLRLQLYGYHSPTNSVLKTDAEELVSRSYWDTLRRNTSQALFSDLAERADDI 333
           K    +      +  G+          D EEL    +   LR + S+  F+ L  +  ++
Sbjct: 893 KAQLAEVVESMFRESGFQ---------DKEELTWEDFHFMLRDHNSELRFTQLCVKGVEV 943

Query: 334 TSLVTD 339
             ++ D
Sbjct: 944 PEVIKD 949



 Score = 35.8 bits (81), Expect = 0.100
 Identities = 30/131 (22%), Positives = 62/131 (47%), Gaps = 23/131 (17%)

Query: 241 FNMFDTDGNEMVDKKEFLVLQEIFRKKNEKREIKGDEEKRAMLRLQLYGYHSPTNSVLKT 300
           F++ D DGN  +  +EFL +  +F        +KG  E+++ L  ++Y +    N ++  
Sbjct: 824 FSLADKDGNGYLSFREFLDILVVF--------MKGSPEEKSRLMFRMYDFDG--NGLISK 873

Query: 301 DAEELVSRSYWDTLRRNTSQALFSDLAERADDITSLVTDTTLLVHFFGKKGKAELNFEDF 360
           D    + RS+ +      S+A  +++ E      S+  ++       G + K EL +EDF
Sbjct: 874 DEFIRMLRSFIEISNNCLSKAQLAEVVE------SMFRES-------GFQDKEELTWEDF 920

Query: 361 YRFMDNLQTEV 371
           +  + +  +E+
Sbjct: 921 HFMLRDHNSEL 931


>gi|4757974 centrin 1 [Homo sapiens]
          Length = 172

 Score = 39.7 bits (91), Expect = 0.007
 Identities = 30/133 (22%), Positives = 63/133 (47%), Gaps = 6/133 (4%)

Query: 238 RIAFNMFDTDGNEMVDKKEFLVLQEIF---RKKNEKREIKGDEEKRAMLRLQLYGYHS-P 293
           R AF++FD DG+  +D KE  V         +K E +++  + ++    ++    + +  
Sbjct: 34  REAFDLFDVDGSGTIDAKELKVAMRALGFEPRKEEMKKMISEVDREGTGKISFNDFLAVM 93

Query: 294 TNSVLKTDAEELVSRSYWDTLRRNTSQALFSDLAERADDITSLVTDTTL--LVHFFGKKG 351
           T  + + D +E + +++       T +  F +L   A+++   +TD  L  ++    + G
Sbjct: 94  TQKMSEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGENLTDEELQEMIDEADRDG 153

Query: 352 KAELNFEDFYRFM 364
             E+N E+F R M
Sbjct: 154 DGEVNEEEFLRIM 166


>gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo
           sapiens]
          Length = 675

 Score = 39.3 bits (90), Expect = 0.009
 Identities = 71/346 (20%), Positives = 130/346 (37%), Gaps = 98/346 (28%)

Query: 149 FRLFASIECEGQLFMTPYDFI---LAVTTDEPKVAKTWKSLSKQELNQMLAETPPVWKGS 205
           F  +ASIE  G+ FM+P DF+   L +  +     KT + LS      ++ +T       
Sbjct: 21  FLKYASIEKNGEFFMSPNDFVTRYLNIFGESQPNPKTVELLSG-----VVDQT------- 68

Query: 206 SKLFRNLKEKGVISYTEYLFLLCILTKPHAGFRIAFNMFDTDGNEMVDKKEFLVLQEIFR 265
                   + G+IS+ E++    +L  P A F +AF +FD  G                 
Sbjct: 69  --------KDGLISFQEFVAFESVLCAPDALFMVAFQLFDKAG----------------- 103

Query: 266 KKNEKREIKGDEEKRAMLRLQLYGYHSPTNSVLKTDAEELVSRSYWDTLRRNTSQALFSD 325
               K E+  ++ K+   +  ++  H P N               WD+            
Sbjct: 104 ----KGEVTFEDVKQVFGQTTIH-QHIPFN---------------WDS------------ 131

Query: 326 LAERADDITSLVTDTTLLVHFFGKKGKAELNFEDFYRFMDNLQTEVLEIEFLSYSNG-MN 384
                           + +HF GK+ K  L + +F +F+  +Q E  +  F+   N    
Sbjct: 132 --------------EFVQLHF-GKERKRHLTYAEFTQFLLEIQLEHAKQAFVQRDNARTG 176

Query: 385 TISEEDFAHILLRYTNVENTSVFLENVRYSI---PEEKGITFDEFRSFFQFLNNLEDFAI 441
            ++  DF  I++        + F+E    +         ++F  F  F   LNN+E   +
Sbjct: 177 RVTAIDFRDIMVT-IRPHVLTPFVEECLVAAAGGTTSHQVSFSYFNGFNSLLNNME---L 232

Query: 442 ALNMYNFASRSIGQDEFKRAVYVATGLKF---SPHLVNTVFKIFDV 484
              +Y+  + +    E  +  +V    KF   +P  V+ +F++ D+
Sbjct: 233 IRKIYSTLAGTRKDVEVTKEEFVLAAQKFGQVTPMEVDILFQLADL 278


>gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo
           sapiens]
          Length = 676

 Score = 39.3 bits (90), Expect = 0.009
 Identities = 71/346 (20%), Positives = 130/346 (37%), Gaps = 98/346 (28%)

Query: 149 FRLFASIECEGQLFMTPYDFI---LAVTTDEPKVAKTWKSLSKQELNQMLAETPPVWKGS 205
           F  +ASIE  G+ FM+P DF+   L +  +     KT + LS      ++ +T       
Sbjct: 21  FLKYASIEKNGEFFMSPNDFVTRYLNIFGESQPNPKTVELLSG-----VVDQT------- 68

Query: 206 SKLFRNLKEKGVISYTEYLFLLCILTKPHAGFRIAFNMFDTDGNEMVDKKEFLVLQEIFR 265
                   + G+IS+ E++    +L  P A F +AF +FD  G                 
Sbjct: 69  --------KDGLISFQEFVAFESVLCAPDALFMVAFQLFDKAG----------------- 103

Query: 266 KKNEKREIKGDEEKRAMLRLQLYGYHSPTNSVLKTDAEELVSRSYWDTLRRNTSQALFSD 325
               K E+  ++ K+   +  ++  H P N               WD+            
Sbjct: 104 ----KGEVTFEDVKQVFGQTTIH-QHIPFN---------------WDS------------ 131

Query: 326 LAERADDITSLVTDTTLLVHFFGKKGKAELNFEDFYRFMDNLQTEVLEIEFLSYSNG-MN 384
                           + +HF GK+ K  L + +F +F+  +Q E  +  F+   N    
Sbjct: 132 --------------EFVQLHF-GKERKRHLTYAEFTQFLLEIQLEHAKQAFVQRDNARTG 176

Query: 385 TISEEDFAHILLRYTNVENTSVFLENVRYSI---PEEKGITFDEFRSFFQFLNNLEDFAI 441
            ++  DF  I++        + F+E    +         ++F  F  F   LNN+E   +
Sbjct: 177 RVTAIDFRDIMVT-IRPHVLTPFVEECLVAAAGGTTSHQVSFSYFNGFNSLLNNME---L 232

Query: 442 ALNMYNFASRSIGQDEFKRAVYVATGLKF---SPHLVNTVFKIFDV 484
              +Y+  + +    E  +  +V    KF   +P  V+ +F++ D+
Sbjct: 233 IRKIYSTLAGTRKDVEVTKEEFVLAAQKFGQVTPMEVDILFQLADL 278


>gi|4757902 caltractin [Homo sapiens]
          Length = 172

 Score = 37.0 bits (84), Expect = 0.045
 Identities = 31/133 (23%), Positives = 61/133 (45%), Gaps = 6/133 (4%)

Query: 238 RIAFNMFDTDGNEMVDKKEFLVLQEIFRKKNEKREIK---GDEEKRAMLRLQLYGYHS-P 293
           R AF++FD DG   +D KE  V       + +K EIK    + +K    ++    + +  
Sbjct: 34  REAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVM 93

Query: 294 TNSVLKTDAEELVSRSYWDTLRRNTSQALFSDLAERADDITSLVTDTTL--LVHFFGKKG 351
           T  + + D +E + +++       T +  F +L   A ++   +TD  L  ++    + G
Sbjct: 94  TQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDG 153

Query: 352 KAELNFEDFYRFM 364
             E++ ++F R M
Sbjct: 154 DGEVSEQEFLRIM 166


>gi|46397403 centrin 3 [Homo sapiens]
          Length = 167

 Score = 37.0 bits (84), Expect = 0.045
 Identities = 31/131 (23%), Positives = 61/131 (46%), Gaps = 6/131 (4%)

Query: 240 AFNMFDTDGNEMVDKKEFLVLQEIFR---KKNEKREIKGDEEKRAMLRLQLYGYHSP-TN 295
           AF +FDTD +E +D  E  V         KK +  +I  D ++ A  ++    ++   T+
Sbjct: 33  AFELFDTDKDEAIDYHELKVAMRALGFDVKKADVLKILKDYDREATGKITFEDFNEVVTD 92

Query: 296 SVLKTDAEELVSRSYWDTLRRNTSQALFSDLAERADDITSLVTDTTL--LVHFFGKKGKA 353
            +L+ D  E + +++      ++ +    +L   A ++   ++D  L  ++  F K G  
Sbjct: 93  WILERDPHEEILKAFKLFDDDDSGKISLRNLRRVARELGENMSDEELRAMIEEFDKDGDG 152

Query: 354 ELNFEDFYRFM 364
           E+N E+F   M
Sbjct: 153 EINQEEFIAIM 163


>gi|22212896 protein phosphatase 3 regulatory subunit B, beta
           isoform [Homo sapiens]
          Length = 173

 Score = 36.6 bits (83), Expect = 0.058
 Identities = 37/159 (23%), Positives = 67/159 (42%), Gaps = 29/159 (18%)

Query: 211 NLKEKGVISYTEYLFLLCILTKPHAGFRIAFNMFDTDGNEMVDKKEFLVLQEIFRKKNEK 270
           +L + G +S  E++ L  +   P    R   ++FDTDG+  VD KEF++    F      
Sbjct: 34  DLDKSGSLSVEEFMSLPELRHNPLV--RRVIDVFDTDGDGEVDFKEFILGTSQF------ 85

Query: 271 REIKGDEEKRAMLRLQLYGYHSPTNSVLKTDAEELVSR-SYWDTLRRNTSQALFSDLAER 329
             +KGDEE++      +Y            D +  +S    +  L+      L     ++
Sbjct: 86  -SVKGDEEQKLRFAFSIY----------DMDKDGYISNGELFQVLKMMVGNNLTDWQLQQ 134

Query: 330 ADDITSLVTDTTLLVHFFGKKGKAELNFEDFYRFMDNLQ 368
             D T ++ D         K G  +++FE+F   + +L+
Sbjct: 135 LVDKTIIILD---------KDGDGKISFEEFSAVVRDLE 164


>gi|132566532 dual oxidase 2 precursor [Homo sapiens]
          Length = 1548

 Score = 34.7 bits (78), Expect = 0.22
 Identities = 28/113 (24%), Positives = 46/113 (40%), Gaps = 11/113 (9%)

Query: 216 GVISYTEYLFLLCILTK--PHAGFRIAFNMFDTDGNEMVDKKEFLVLQEIFRKKNEKREI 273
           G +S+ E+L +L +  K  P    R+ F M+D D N  + K EF  +   F + +     
Sbjct: 837 GYLSFREFLDILVVFMKGSPEDKSRLMFTMYDLDENGFLSKDEFFTMMRSFIEISNNCLS 896

Query: 274 KGDEEKRAMLRLQLYGYHSPTNSVLKTDAEELVSRSYWDTLRRNTSQALFSDL 326
           K    +      +  G+          D EEL    +   LR + S+  F+ L
Sbjct: 897 KAQLAEVVESMFRESGFQ---------DKEELTWEDFHFMLRDHDSELRFTQL 940



 Score = 33.5 bits (75), Expect = 0.49
 Identities = 31/131 (23%), Positives = 58/131 (44%), Gaps = 23/131 (17%)

Query: 241 FNMFDTDGNEMVDKKEFLVLQEIFRKKNEKREIKGDEEKRAMLRLQLYGYHSPTNSVLKT 300
           F++ D DGN  +  +EFL +  +F        +KG  E ++ L   +Y      N  L  
Sbjct: 828 FSLADKDGNGYLSFREFLDILVVF--------MKGSPEDKSRLMFTMYDLDE--NGFLSK 877

Query: 301 DAEELVSRSYWDTLRRNTSQALFSDLAERADDITSLVTDTTLLVHFFGKKGKAELNFEDF 360
           D    + RS+ +      S+A  +++ E      S+  ++       G + K EL +EDF
Sbjct: 878 DEFFTMMRSFIEISNNCLSKAQLAEVVE------SMFRES-------GFQDKEELTWEDF 924

Query: 361 YRFMDNLQTEV 371
           +  + +  +E+
Sbjct: 925 HFMLRDHDSEL 935


>gi|98985795 neurocalcin delta [Homo sapiens]
          Length = 193

 Score = 34.7 bits (78), Expect = 0.22
 Identities = 22/71 (30%), Positives = 38/71 (53%), Gaps = 6/71 (8%)

Query: 216 GVISYTEYLFLLCILT--KPHAGFRIAFNMFDTDGNEMVDKKEFL-VLQEIFRKKNEKRE 272
           G I + E++  L + +  K     + AF+M+D DGN  + K E L ++Q I++  +   +
Sbjct: 78  GTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMK 137

Query: 273 IKGDE---EKR 280
           +  DE   EKR
Sbjct: 138 MPEDESTPEKR 148


>gi|98985793 neurocalcin delta [Homo sapiens]
          Length = 193

 Score = 34.7 bits (78), Expect = 0.22
 Identities = 22/71 (30%), Positives = 38/71 (53%), Gaps = 6/71 (8%)

Query: 216 GVISYTEYLFLLCILT--KPHAGFRIAFNMFDTDGNEMVDKKEFL-VLQEIFRKKNEKRE 272
           G I + E++  L + +  K     + AF+M+D DGN  + K E L ++Q I++  +   +
Sbjct: 78  GTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMK 137

Query: 273 IKGDE---EKR 280
           +  DE   EKR
Sbjct: 138 MPEDESTPEKR 148


>gi|98985791 neurocalcin delta [Homo sapiens]
          Length = 193

 Score = 34.7 bits (78), Expect = 0.22
 Identities = 22/71 (30%), Positives = 38/71 (53%), Gaps = 6/71 (8%)

Query: 216 GVISYTEYLFLLCILT--KPHAGFRIAFNMFDTDGNEMVDKKEFL-VLQEIFRKKNEKRE 272
           G I + E++  L + +  K     + AF+M+D DGN  + K E L ++Q I++  +   +
Sbjct: 78  GTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMK 137

Query: 273 IKGDE---EKR 280
           +  DE   EKR
Sbjct: 138 MPEDESTPEKR 148


>gi|98985789 neurocalcin delta [Homo sapiens]
          Length = 193

 Score = 34.7 bits (78), Expect = 0.22
 Identities = 22/71 (30%), Positives = 38/71 (53%), Gaps = 6/71 (8%)

Query: 216 GVISYTEYLFLLCILT--KPHAGFRIAFNMFDTDGNEMVDKKEFL-VLQEIFRKKNEKRE 272
           G I + E++  L + +  K     + AF+M+D DGN  + K E L ++Q I++  +   +
Sbjct: 78  GTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMK 137

Query: 273 IKGDE---EKR 280
           +  DE   EKR
Sbjct: 138 MPEDESTPEKR 148


>gi|98985787 neurocalcin delta [Homo sapiens]
          Length = 193

 Score = 34.7 bits (78), Expect = 0.22
 Identities = 22/71 (30%), Positives = 38/71 (53%), Gaps = 6/71 (8%)

Query: 216 GVISYTEYLFLLCILT--KPHAGFRIAFNMFDTDGNEMVDKKEFL-VLQEIFRKKNEKRE 272
           G I + E++  L + +  K     + AF+M+D DGN  + K E L ++Q I++  +   +
Sbjct: 78  GTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMK 137

Query: 273 IKGDE---EKR 280
           +  DE   EKR
Sbjct: 138 MPEDESTPEKR 148


>gi|98985785 neurocalcin delta [Homo sapiens]
          Length = 193

 Score = 34.7 bits (78), Expect = 0.22
 Identities = 22/71 (30%), Positives = 38/71 (53%), Gaps = 6/71 (8%)

Query: 216 GVISYTEYLFLLCILT--KPHAGFRIAFNMFDTDGNEMVDKKEFL-VLQEIFRKKNEKRE 272
           G I + E++  L + +  K     + AF+M+D DGN  + K E L ++Q I++  +   +
Sbjct: 78  GTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMK 137

Query: 273 IKGDE---EKR 280
           +  DE   EKR
Sbjct: 138 MPEDESTPEKR 148


>gi|98985783 neurocalcin delta [Homo sapiens]
          Length = 193

 Score = 34.7 bits (78), Expect = 0.22
 Identities = 22/71 (30%), Positives = 38/71 (53%), Gaps = 6/71 (8%)

Query: 216 GVISYTEYLFLLCILT--KPHAGFRIAFNMFDTDGNEMVDKKEFL-VLQEIFRKKNEKRE 272
           G I + E++  L + +  K     + AF+M+D DGN  + K E L ++Q I++  +   +
Sbjct: 78  GTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMK 137

Query: 273 IKGDE---EKR 280
           +  DE   EKR
Sbjct: 138 MPEDESTPEKR 148


>gi|98985778 neurocalcin delta [Homo sapiens]
          Length = 193

 Score = 34.7 bits (78), Expect = 0.22
 Identities = 22/71 (30%), Positives = 38/71 (53%), Gaps = 6/71 (8%)

Query: 216 GVISYTEYLFLLCILT--KPHAGFRIAFNMFDTDGNEMVDKKEFL-VLQEIFRKKNEKRE 272
           G I + E++  L + +  K     + AF+M+D DGN  + K E L ++Q I++  +   +
Sbjct: 78  GTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMK 137

Query: 273 IKGDE---EKR 280
           +  DE   EKR
Sbjct: 138 MPEDESTPEKR 148


>gi|19913446 hippocalcin [Homo sapiens]
          Length = 193

 Score = 34.3 bits (77), Expect = 0.29
 Identities = 20/71 (28%), Positives = 40/71 (56%), Gaps = 6/71 (8%)

Query: 216 GVISYTEYLFLLCILTKPHAGFRI--AFNMFDTDGNEMVDKKEFL-VLQEIFRKKNEKRE 272
           G I + E++  L + ++     ++  AF+M+D DGN  + ++E L ++Q I++  +   +
Sbjct: 78  GTIDFREFIIALSVTSRGRLEQKLMWAFSMYDLDGNGYISREEMLEIVQAIYKMVSSVMK 137

Query: 273 IKGDE---EKR 280
           +  DE   EKR
Sbjct: 138 MPEDESTPEKR 148


>gi|4506025 protein phosphatase 3, regulatory subunit B, alpha
           isoform 1 [Homo sapiens]
          Length = 170

 Score = 33.9 bits (76), Expect = 0.38
 Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 9/78 (11%)

Query: 211 NLKEKGVISYTEYLFLLCILTKPHAGFRIAFNMFDTDGNEMVDKKEFLVLQEIFRKKNEK 270
           +L   G +S  E++ L  +   P    +   ++FDTDGN  VD KEF+     F      
Sbjct: 31  DLDNSGSLSVEEFMSLPELQQNPLV--QRVIDIFDTDGNGEVDFKEFIEGVSQF------ 82

Query: 271 REIKGDEEKRAMLRLQLY 288
             +KGD+E++     ++Y
Sbjct: 83  -SVKGDKEQKLRFAFRIY 99


>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
           sapiens]
          Length = 2715

 Score = 33.9 bits (76), Expect = 0.38
 Identities = 30/106 (28%), Positives = 40/106 (37%), Gaps = 11/106 (10%)

Query: 10  PPPRVSPPLCAHQPLLGPWGRPAVTTLGLPGRPFSSREDEER----AVAEAAWRRRRRWG 65
           PPP + PP  +  P L P   P V+   LP  P    ++E+      V  A   R+R   
Sbjct: 413 PPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRP 472

Query: 66  ELSVAAAAGGGLVGLVCYQLYGDPRAGSPATGRPSKSAATEPEDPP 111
            L+ +  A               P   SP T  PS +    PED P
Sbjct: 473 PLTPSQRAEREAA-------RAGPEGTSPPTPTPSTATGGPPEDSP 511


>gi|19913443 hippocalcin-like 1 [Homo sapiens]
          Length = 193

 Score = 33.9 bits (76), Expect = 0.38
 Identities = 21/71 (29%), Positives = 38/71 (53%), Gaps = 6/71 (8%)

Query: 216 GVISYTEYLFLLCILT--KPHAGFRIAFNMFDTDGNEMVDKKEFL-VLQEIFRKKNEKRE 272
           G I + E++  L + +  K     + AF+M+D DGN  + + E L ++Q I++  +   +
Sbjct: 78  GTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSEMLEIVQAIYKMVSSVMK 137

Query: 273 IKGDE---EKR 280
           +  DE   EKR
Sbjct: 138 MPEDESTPEKR 148


>gi|19913441 hippocalcin-like 1 [Homo sapiens]
          Length = 193

 Score = 33.9 bits (76), Expect = 0.38
 Identities = 21/71 (29%), Positives = 38/71 (53%), Gaps = 6/71 (8%)

Query: 216 GVISYTEYLFLLCILT--KPHAGFRIAFNMFDTDGNEMVDKKEFL-VLQEIFRKKNEKRE 272
           G I + E++  L + +  K     + AF+M+D DGN  + + E L ++Q I++  +   +
Sbjct: 78  GTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSEMLEIVQAIYKMVSSVMK 137

Query: 273 IKGDE---EKR 280
           +  DE   EKR
Sbjct: 138 MPEDESTPEKR 148


>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
          Length = 2161

 Score = 33.5 bits (75), Expect = 0.49
 Identities = 36/107 (33%), Positives = 44/107 (41%), Gaps = 13/107 (12%)

Query: 10   PPPRVSPPLCAHQPLLGPWGR----PAVTTLGLPGRPFSSREDEERAVAEAAWRRRRRWG 65
            P P    P   H+P+L  WG     PA   LG       S+E    A   AA  RR    
Sbjct: 1390 PTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRA-GLGSQEKSLPASPPAA--RRSLLH 1446

Query: 66   ELSVAAAAGGGLVGLVCYQLYGDPRAGSPATGRPSKSAATEPEDPPR 112
             L   A      VG +  QL  +P A  P   +P +SAA  PE+P R
Sbjct: 1447 RLPPTAPG----VGPLLLQLGTEPPAPHPGVSKPWRSAA--PEEPER 1487



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 38/144 (26%), Positives = 58/144 (40%), Gaps = 27/144 (18%)

Query: 10   PPPRVSPPLCAHQPLLGPW--GRPAVTTLGLPGRPFSSREDEERAVAEAAWRRRRRWGEL 67
            PPPR++      QP L  W  G P+ T    PG P  S          ++     R+ +L
Sbjct: 1035 PPPRLA---LGPQPSLRGWRGGGPSPT----PGAPSPSHHGSAGGGGGSSQGPALRYFQL 1087

Query: 68   S---------VAAAAGGGLVGLVCYQ--LYGDPRAGSPATGRPSKSAATEPEDP-----P 111
                      V A +G G  G +  Q  + G+P+ G      PS ++   P+ P     P
Sbjct: 1088 PPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPPPAVAAP 1147

Query: 112  RGRGMLPIP--VAAAKETVAIGRT 133
              +  +PIP  +  A  T + GR+
Sbjct: 1148 SEKNSIPIPTIIIKAPSTSSSGRS 1171


>gi|23065526 growth arrest-specific 2 like 1 isoform a [Homo
           sapiens]
          Length = 681

 Score = 32.7 bits (73), Expect = 0.84
 Identities = 32/88 (36%), Positives = 41/88 (46%), Gaps = 7/88 (7%)

Query: 22  QPLLGPWGRPAVTTLGLPGRPFSSREDEERAVAEAAWRRRRRWGELS-VAAAAGGGLVGL 80
           +P   P GR A  ++  P R   S+  EE+AV      RR R G+ S V    G G  G 
Sbjct: 413 RPRGAPGGRGAQLSVPSPARRARSQSREEQAVLLV---RRDRDGQHSWVPRGRGSGGSGR 469

Query: 81  VCYQLYGDPRAGSPATGRPSKSAATEPE 108
              Q    PRA SPA  R S+ ++  PE
Sbjct: 470 STPQT---PRARSPAAPRLSRVSSPSPE 494


>gi|19923777 growth arrest-specific 2 like 1 isoform a [Homo
           sapiens]
          Length = 681

 Score = 32.7 bits (73), Expect = 0.84
 Identities = 32/88 (36%), Positives = 41/88 (46%), Gaps = 7/88 (7%)

Query: 22  QPLLGPWGRPAVTTLGLPGRPFSSREDEERAVAEAAWRRRRRWGELS-VAAAAGGGLVGL 80
           +P   P GR A  ++  P R   S+  EE+AV      RR R G+ S V    G G  G 
Sbjct: 413 RPRGAPGGRGAQLSVPSPARRARSQSREEQAVLLV---RRDRDGQHSWVPRGRGSGGSGR 469

Query: 81  VCYQLYGDPRAGSPATGRPSKSAATEPE 108
              Q    PRA SPA  R S+ ++  PE
Sbjct: 470 STPQT---PRARSPAAPRLSRVSSPSPE 494


>gi|40254415 guanylate cyclase activator 1A (retina) [Homo sapiens]
          Length = 201

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 16/60 (26%), Positives = 30/60 (50%), Gaps = 2/60 (3%)

Query: 211 NLKEKGVISYTEYLFLLCILTKPHAGFRIA--FNMFDTDGNEMVDKKEFLVLQEIFRKKN 268
           +  + G I + EY+  L ++ K     ++   F ++D DGN  +D+ E L + +  R  N
Sbjct: 64  DFNKDGYIDFMEYVAALSLVLKGKVEQKLRWYFKLYDVDGNGCIDRDELLTIIQAIRAIN 123


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,421,182
Number of Sequences: 37866
Number of extensions: 972127
Number of successful extensions: 4458
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 36
Number of HSP's successfully gapped in prelim test: 84
Number of HSP's that attempted gapping in prelim test: 4294
Number of HSP's gapped (non-prelim): 238
length of query: 530
length of database: 18,247,518
effective HSP length: 107
effective length of query: 423
effective length of database: 14,195,856
effective search space: 6004847088
effective search space used: 6004847088
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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