Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 31982927
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31982927 acetoacetyl-CoA synthetase [Homo sapiens]
(672 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31982927 acetoacetyl-CoA synthetase [Homo sapiens] 1365 0.0
gi|8923896 acyl-CoA synthetase short-chain family member 2 isofo... 206 7e-53
gi|253970489 acyl-CoA synthetase short-chain family member 2 iso... 201 1e-51
gi|28416953 acyl-CoA synthetase short-chain family member 1 [Hom... 172 7e-43
gi|13375727 acyl-CoA synthetase short-chain family member 3 [Hom... 119 7e-27
gi|122937307 acyl-CoA synthetase medium-chain family member 4 [H... 65 2e-10
gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens] 65 2e-10
gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Ho... 63 1e-09
gi|157311624 acyl-CoA synthetase medium-chain family member 2B [... 56 9e-08
gi|157311622 acyl-CoA synthetase medium-chain family member 2B [... 56 9e-08
gi|58082049 acyl-CoA synthetase medium-chain family member 2A [H... 56 1e-07
gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase AC... 51 4e-06
gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase AC... 51 4e-06
gi|115511026 acyl-CoA synthetase medium-chain family member 1 [H... 48 3e-05
gi|42544132 SA hypertension-associated homolog isoform 1 [Homo s... 47 4e-05
gi|45580730 aminoadipate-semialdehyde dehydrogenase [Homo sapiens] 41 0.004
gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Ho... 38 0.035
gi|227499619 solute carrier family 27 (fatty acid transporter), ... 37 0.059
gi|27477105 lipidosin [Homo sapiens] 37 0.077
gi|206597513 ArfGAP with RhoGAP domain, ankyrin repeat and PH do... 35 0.23
gi|92091600 ArfGAP with RhoGAP domain, ankyrin repeat and PH dom... 35 0.23
gi|227499621 solute carrier family 27 (fatty acid transporter), ... 34 0.50
gi|62865631 solute carrier family 27 (fatty acid transporter), m... 34 0.50
gi|13325055 solute carrier family 27 (fatty acid transporter), m... 34 0.50
gi|42544134 SA hypertension-associated homolog isoform 2 [Homo s... 32 1.5
gi|206597515 ArfGAP with RhoGAP domain, ankyrin repeat and PH do... 32 2.5
gi|109948283 KIAA0020 protein [Homo sapiens] 32 2.5
gi|18104962 amyloid beta precursor protein-binding protein 2 [Ho... 32 2.5
gi|145312259 tudor and KH domain containing isoform a [Homo sapi... 32 2.5
gi|145312246 tudor and KH domain containing isoform b [Homo sapi... 32 2.5
>gi|31982927 acetoacetyl-CoA synthetase [Homo sapiens]
Length = 672
Score = 1365 bits (3534), Expect = 0.0
Identities = 672/672 (100%), Positives = 672/672 (100%)
Query: 1 MSKEERPGREEILECQVMWEPDSKKNTQMDRFRAAVGAACGLALESYDDLYHWSVESYSD 60
MSKEERPGREEILECQVMWEPDSKKNTQMDRFRAAVGAACGLALESYDDLYHWSVESYSD
Sbjct: 1 MSKEERPGREEILECQVMWEPDSKKNTQMDRFRAAVGAACGLALESYDDLYHWSVESYSD 60
Query: 61 FWAEFWKFSGIVFSRVYDEVVDTSKGIADVPEWFKGSRLNYAENLLRHKENDRVALYIAR 120
FWAEFWKFSGIVFSRVYDEVVDTSKGIADVPEWFKGSRLNYAENLLRHKENDRVALYIAR
Sbjct: 61 FWAEFWKFSGIVFSRVYDEVVDTSKGIADVPEWFKGSRLNYAENLLRHKENDRVALYIAR 120
Query: 121 EGKEEIVKVTFEELRQEVALFAAAMRKMGVKKGDRVVGYLPNSEHAVEAMLAAASIGAIW 180
EGKEEIVKVTFEELRQEVALFAAAMRKMGVKKGDRVVGYLPNSEHAVEAMLAAASIGAIW
Sbjct: 121 EGKEEIVKVTFEELRQEVALFAAAMRKMGVKKGDRVVGYLPNSEHAVEAMLAAASIGAIW 180
Query: 181 SSTSPDFGVNGVLDRFSQIQPKLIFSVEAVVYNGKEHNHMEKLQQVVKGLPDLKKVVVIP 240
SSTSPDFGVNGVLDRFSQIQPKLIFSVEAVVYNGKEHNHMEKLQQVVKGLPDLKKVVVIP
Sbjct: 181 SSTSPDFGVNGVLDRFSQIQPKLIFSVEAVVYNGKEHNHMEKLQQVVKGLPDLKKVVVIP 240
Query: 241 YVSSRENIDLSKIPNSVFLDDFLATGTSEQAPQLEFEQLPFSHPLFIMFSSGTTGAPKCM 300
YVSSRENIDLSKIPNSVFLDDFLATGTSEQAPQLEFEQLPFSHPLFIMFSSGTTGAPKCM
Sbjct: 241 YVSSRENIDLSKIPNSVFLDDFLATGTSEQAPQLEFEQLPFSHPLFIMFSSGTTGAPKCM 300
Query: 301 VHSAGGTLIQHLKEHLLHGNMTSSDILLCYTTVGWMMWNWMVSLLATGAAMVLYDGSPLV 360
VHSAGGTLIQHLKEHLLHGNMTSSDILLCYTTVGWMMWNWMVSLLATGAAMVLYDGSPLV
Sbjct: 301 VHSAGGTLIQHLKEHLLHGNMTSSDILLCYTTVGWMMWNWMVSLLATGAAMVLYDGSPLV 360
Query: 361 PTPNVLWDLVDRIGITVLVTGAKWLSVLEEKAMKPVETHSLQMLHTILSTGSPLKAQSYE 420
PTPNVLWDLVDRIGITVLVTGAKWLSVLEEKAMKPVETHSLQMLHTILSTGSPLKAQSYE
Sbjct: 361 PTPNVLWDLVDRIGITVLVTGAKWLSVLEEKAMKPVETHSLQMLHTILSTGSPLKAQSYE 420
Query: 421 YVYRCIKSSILLGSISGGTDIISCFMGHNFSLPVYKGEIQARNLGMAVEAWNEEGKAVWG 480
YVYRCIKSSILLGSISGGTDIISCFMGHNFSLPVYKGEIQARNLGMAVEAWNEEGKAVWG
Sbjct: 421 YVYRCIKSSILLGSISGGTDIISCFMGHNFSLPVYKGEIQARNLGMAVEAWNEEGKAVWG 480
Query: 481 ESGELVCTKPIPCQPTHFWNDENGNKYRKAYFSKFPGIWAHGDYCRINPKTGGIVMLGRS 540
ESGELVCTKPIPCQPTHFWNDENGNKYRKAYFSKFPGIWAHGDYCRINPKTGGIVMLGRS
Sbjct: 481 ESGELVCTKPIPCQPTHFWNDENGNKYRKAYFSKFPGIWAHGDYCRINPKTGGIVMLGRS 540
Query: 541 DGTLNPNGVRFGSSEIYNIVESFEEVEDSLCVPQYNKYREERVILFLKMASGHAFQPDLV 600
DGTLNPNGVRFGSSEIYNIVESFEEVEDSLCVPQYNKYREERVILFLKMASGHAFQPDLV
Sbjct: 541 DGTLNPNGVRFGSSEIYNIVESFEEVEDSLCVPQYNKYREERVILFLKMASGHAFQPDLV 600
Query: 601 KRIRDAIRMGLSARHVPSLILETKGIPYTLNGKKVEVAVKQIIAGKAVEQGGAFSNPETL 660
KRIRDAIRMGLSARHVPSLILETKGIPYTLNGKKVEVAVKQIIAGKAVEQGGAFSNPETL
Sbjct: 601 KRIRDAIRMGLSARHVPSLILETKGIPYTLNGKKVEVAVKQIIAGKAVEQGGAFSNPETL 660
Query: 661 DLYRDIPELQGF 672
DLYRDIPELQGF
Sbjct: 661 DLYRDIPELQGF 672
>gi|8923896 acyl-CoA synthetase short-chain family member 2 isoform
1 [Homo sapiens]
Length = 701
Score = 206 bits (523), Expect = 7e-53
Identities = 168/640 (26%), Positives = 289/640 (45%), Gaps = 52/640 (8%)
Query: 43 ALESYDDLYHWSVESYSDFWAE-----FWKFSGIVFSRVYDEVVDTSKGIADVPEWFKGS 97
+L+ Y +L+ SVE +FW + +WK Y+ D +KG + EW KG+
Sbjct: 43 SLQRYRELHRRSVEEPREFWGDIAKEFYWKTPCPGPFLRYN--FDVTKGKIFI-EWMKGA 99
Query: 98 RLNYAENLL-----RHKENDRVALYIAREGKEEIVKVTFEELRQEVALFAAAMRKMGVKK 152
N N+L K D+VA Y E ++T+ +L +V F+ +RK G++K
Sbjct: 100 TTNICYNVLDRNVHEKKLGDKVAFYWEGNEPGETTQITYHQLLVQVCQFSNVLRKQGIQK 159
Query: 153 GDRVVGYLPNSEHAVEAMLAAASIGAIWSSTSPDFGVNGVLDRFSQIQPKLIFSVEAVVY 212
GDRV Y+P V AMLA A IGA+ S F + +R L+ + +A Y
Sbjct: 160 GDRVAIYMPMIPELVVAMLACARIGALHSIVFAGFSSESLCERILDSSCSLLITTDAF-Y 218
Query: 213 NGKEHNHMEKLQQVV------KGLPDLKKVVVIPYVSSRE---------------NIDLS 251
G++ ++++L KG P ++ +V+ ++ E +
Sbjct: 219 RGEKLVNLKELADEALQKCQEKGFP-VRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDV 277
Query: 252 KIPNSVFLDDFLATGTSEQAPQLEFEQLPFSHPLFIMFSSGTTGAPKCMVHSAGGTLIQH 311
+I + +D + E + E E PLFI+++SG+TG PK +VH+ GG ++
Sbjct: 278 QISWNQGIDLWWHELMQEAGDECEPEWCDAEDPLFILYTSGSTGKPKGVVHTVGGYMLYV 337
Query: 312 LKEHLLHGNMTSSDILLCYTTVGWMMWNWMVSL--LATGAAMVLYDGSPLVPTPNVLWDL 369
+ + D+ C +GW+ + V+ LA GA VL++G P P N LW +
Sbjct: 338 ATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEGIPTYPDVNRLWSI 397
Query: 370 VDRIGITVLVTGAKWLSVLEEKAMKPVETHSLQMLHTILSTGSPLKAQSYEYVYRCIKSS 429
VD+ +T T + +L + +PV HS L + + G P+ +++ + +R + +
Sbjct: 398 VDKYKVTKFYTAPTAIRLLMKFGDEPVTKHSRASLQVLGTVGEPINPEAWLWYHRVVGAQ 457
Query: 430 -----ILLGSISGGTDIISCFMGHNFSLPVYKGEIQARNLGMAVEAWNEEGKAVWGES-G 483
G +++ G + P+ G G+A NE G+ + GE+ G
Sbjct: 458 RCPIVDTFWQTETGGHMLTPLPG---ATPMKPGSATFPFFGVAPAILNESGEELEGEAEG 514
Query: 484 ELVCTKPIP-CQPTHFWNDENGNKYRKAYFSKFPGIWAHGDYCRINPKTGGIVMLGRSDG 542
LV +P P T + N E ++ YF KFPG + GD C+ + G + GR D
Sbjct: 515 YLVFKQPWPGIMRTVYGNHE---RFETTYFKKFPGYYVTGDGCQ-RDQDGYYWITGRIDD 570
Query: 543 TLNPNGVRFGSSEIYNIVESFEEVEDSLCVPQYNKYREERVILFLKMASGHAFQPDLVKR 602
LN +G ++E+ + + E V ++ V + + E + F+ + GH F P L +
Sbjct: 571 MLNVSGHLLSTAEVESALVEHEAVAEAAVVGHPHPVKGECLYCFVTLCDGHTFSPKLTEE 630
Query: 603 IRDAIRMGLSARHVPSLILETKGIPYTLNGKKVEVAVKQI 642
++ IR + P I G+P T +GK + +++I
Sbjct: 631 LKKQIREKIGPIATPDYIQNAPGLPKTRSGKIMRRVLRKI 670
>gi|253970489 acyl-CoA synthetase short-chain family member 2
isoform 2 [Homo sapiens]
Length = 714
Score = 201 bits (512), Expect = 1e-51
Identities = 169/652 (25%), Positives = 286/652 (43%), Gaps = 63/652 (9%)
Query: 43 ALESYDDLYHWSVESYSDFWAE-----FWKFSGIVFSRVYDEVVDTSKGIADVPEWFKGS 97
+L+ Y +L+ SVE +FW + +WK Y+ D +KG + EW KG+
Sbjct: 43 SLQRYRELHRRSVEEPREFWGDIAKEFYWKTPCPGPFLRYN--FDVTKGKIFI-EWMKGA 99
Query: 98 RLNYAENLL-----RHKENDRVALYIAREGKEEIVKVTFEELRQEVALFAAAMRKMGVKK 152
N N+L K D+VA Y E ++T+ +L +V F+ +RK G++K
Sbjct: 100 TTNICYNVLDRNVHEKKLGDKVAFYWEGNEPGETTQITYHQLLVQVCQFSNVLRKQGIQK 159
Query: 153 GDRVVGYLPNSEHAVEAMLAAASIGAIWSSTSPDFGVNGVLDRFSQIQPKLIFSVEAVVY 212
GDRV Y+P V AMLA A IGA+ S F + +R L+ + +A Y
Sbjct: 160 GDRVAIYMPMIPELVVAMLACARIGALHSIVFAGFSSESLCERILDSSCSLLITTDAF-Y 218
Query: 213 NGKEHNHMEKLQQVV------KGLPDLKKVVV-----------------------IPYVS 243
G++ ++++L KG P +VV P V
Sbjct: 219 RGEKLVNLKELADEALQKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDVQ 278
Query: 244 SRENIDLSKIPNSVF----LDDFLATGTSEQAPQLEFEQLPFSHPLFIMFSSGTTGAPKC 299
+ ++ + +D + E + E E PLFI+++SG+TG PK
Sbjct: 279 GKLKEKSKRVQPQISWNQGIDLWWHELMQEAGDECEPEWCDAEDPLFILYTSGSTGKPKG 338
Query: 300 MVHSAGGTLIQHLKEHLLHGNMTSSDILLCYTTVGWMMWNWMVSL--LATGAAMVLYDGS 357
+VH+ GG ++ + + D+ C +GW+ + V+ LA GA VL++G
Sbjct: 339 VVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEGI 398
Query: 358 PLVPTPNVLWDLVDRIGITVLVTGAKWLSVLEEKAMKPVETHSLQMLHTILSTGSPLKAQ 417
P P N LW +VD+ +T T + +L + +PV HS L + + G P+ +
Sbjct: 399 PTYPDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEPVTKHSRASLQVLGTVGEPINPE 458
Query: 418 SYEYVYRCIKSS-----ILLGSISGGTDIISCFMGHNFSLPVYKGEIQARNLGMAVEAWN 472
++ + +R + + G +++ G + P+ G G+A N
Sbjct: 459 AWLWYHRVVGAQRCPIVDTFWQTETGGHMLTPLPG---ATPMKPGSATFPFFGVAPAILN 515
Query: 473 EEGKAVWGES-GELVCTKPIP-CQPTHFWNDENGNKYRKAYFSKFPGIWAHGDYCRINPK 530
E G+ + GE+ G LV +P P T + N E ++ YF KFPG + GD C+ +
Sbjct: 516 ESGEELEGEAEGYLVFKQPWPGIMRTVYGNHE---RFETTYFKKFPGYYVTGDGCQ-RDQ 571
Query: 531 TGGIVMLGRSDGTLNPNGVRFGSSEIYNIVESFEEVEDSLCVPQYNKYREERVILFLKMA 590
G + GR D LN +G ++E+ + + E V ++ V + + E + F+ +
Sbjct: 572 DGYYWITGRIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVVGHPHPVKGECLYCFVTLC 631
Query: 591 SGHAFQPDLVKRIRDAIRMGLSARHVPSLILETKGIPYTLNGKKVEVAVKQI 642
GH F P L + ++ IR + P I G+P T +GK + +++I
Sbjct: 632 DGHTFSPKLTEELKKQIREKIGPIATPDYIQNAPGLPKTRSGKIMRRVLRKI 683
>gi|28416953 acyl-CoA synthetase short-chain family member 1 [Homo
sapiens]
Length = 689
Score = 172 bits (437), Expect = 7e-43
Identities = 150/627 (23%), Positives = 269/627 (42%), Gaps = 28/627 (4%)
Query: 38 AACGLALESYDDLYHWSVESYSDFWAEFWKFSGIVFSRVYDEVVDTSKGIADVPEWFKGS 97
AA SY L + + FW + + +V+ Y V D + WF G
Sbjct: 49 AAAAAQPGSYPALSAQAAREPAAFWGPLARDT-LVWDTPYHTVWDCDFSTGKIG-WFLGG 106
Query: 98 RLNYAENLLRH---KENDRVALYIAREGKEEIVKVTFEELRQEVALFAAAMRKMGVKKGD 154
+LN + N L K + VAL R+ V++T+ EL + A +++ GV +GD
Sbjct: 107 QLNVSVNCLDQHVRKSPESVALIWERDEPGTEVRITYRELLETTCRLANTLKRHGVHRGD 166
Query: 155 RVVGYLPNSEHAVEAMLAAASIGAIWSSTSPDFGVNGVLDRFSQIQPKLIFSVEAVVYNG 214
RV Y+P S AV AMLA A IGA+ + F + R + + K++ + + G
Sbjct: 167 RVAIYMPVSPLAVAAMLACARIGAVHTVIFAGFSAESLAGRINDAKCKVVITFNQGLRGG 226
Query: 215 KEHNHMEKLQQVVKGLPDLKKVVVIPYVSSRENIDLSKIPNSVFLDDFLATGTSEQAPQL 274
+ + + + VK P ++ V+V ++ ++ +P L +++ P
Sbjct: 227 RVVELKKIVDEAVKHCPTVQHVLVAHRTDNKVHMGDLDVP--------LEQEMAKEDPVC 278
Query: 275 EFEQLPFSHPLFIMFSSGTTGAPKCMVHSAGGTLIQHLKEHLLHGNMTSSDILLCYTTVG 334
E + LF++++SG+TG PK +VH+ G L+ H L + DI C +G
Sbjct: 279 APESMGSEDMLFMLYTSGSTGMPKGIVHTQAGYLLYAALTHKLVFDHQPGDIFGCVADIG 338
Query: 335 WMMWNWMVSL--LATGAAMVLYDGSPLVPTPNVLWDLVDRIGITVLVTGAKWLSVLEEKA 392
W+ + V L GA VL++ +P+ P W+ V+R+ I + +L +
Sbjct: 339 WITGHSYVVYGPLCNGATSVLFESTPVYPNAGRYWETVERLKINQFYGAPTAVRLLLKYG 398
Query: 393 MKPVETHSLQMLHTILSTGSPLKAQSYEYVYRCIKSSILL------GSISGGTDIISCFM 446
V+ + L T+ S G P+ +++E+++R + S + +GG I
Sbjct: 399 DAWVKKYDRSSLRTLGSVGEPINCEAWEWLHRVVGDSRCTLVDTWWQTETGGICIAP--R 456
Query: 447 GHNFSLPVYKGEIQARNLGMAVEAWNEEGKAVWGE--SGELVCTKPIPCQPTHFWNDENG 504
+ G+ +E+G V G SG L ++ P + D
Sbjct: 457 PSEEGAEILPAMAMRPFFGIVPVLMDEKGSVVEGSNVSGALCISQAWPGMARTIYGDHQ- 515
Query: 505 NKYRKAYFSKFPGIWAHGDYCRINPKTGGIVMLGRSDGTLNPNGVRFGSSEIYNIVESFE 564
++ AYF +PG + GD + G + GR D +N +G R G++EI + +
Sbjct: 516 -RFVDAYFKAYPGYYFTGDGA-YRTEGGYYQITGRMDDVINISGHRLGTAEIEDAIADHP 573
Query: 565 EVEDSLCVPQYNKYREERVILFLKMASGHAFQPDLVKRIRDAIRMGLSARHVPSLILETK 624
V +S + + + E F+ + +V+ ++ + ++ VP IL K
Sbjct: 574 AVPESAVIGYPHDIKGEAAFAFIVVKDSAGDSDVVVQELKSMVATKIAKYAVPDEILVVK 633
Query: 625 GIPYTLNGKKVEVAVKQIIAGKAVEQG 651
+P T +GK + +++II +A E G
Sbjct: 634 RLPKTRSGKVMRRLLRKIITSEAQELG 660
>gi|13375727 acyl-CoA synthetase short-chain family member 3 [Homo
sapiens]
Length = 686
Score = 119 bits (299), Expect = 7e-27
Identities = 135/594 (22%), Positives = 249/594 (41%), Gaps = 53/594 (8%)
Query: 93 WFKGSRLNYAENLL-RHKEN---DRVALYIAREGKEEIVKVTFEELRQEVALFAAAMRKM 148
WF LN N + RH EN D++A+ T++E+ ++V+ A + K
Sbjct: 104 WFVEGMLNICYNAVDRHIENGKGDKIAIIYDSPVTNTKATFTYKEVLEQVSKLAGVLVKH 163
Query: 149 GVKKGDRVVGYLPNSEHAVEAMLAAASIGAIWSSTSPDFGVNGVLDRFSQIQPKLIFSVE 208
G+KKGD VV Y+P A+ MLA A IGAI S F + R ++PK++ +
Sbjct: 164 GIKKGDTVVIYMPMIPQAMYTMLACARIGAIHSLIFGGFASKELSSRIDHVKPKVVVTAS 223
Query: 209 AVVYNGKEHNHMEKLQQVVK-GLPDLKKVVVIPYVSSRENIDLSKIPNSVFLDDFLATGT 267
+ G+ ++ +++ +K G K+++ +R N++ + LD
Sbjct: 224 FGIEPGRRVEYVPLVEEALKIGQHKPDKILIY----NRPNMEAVPLAPGRDLD-----WD 274
Query: 268 SEQAPQLEFEQLPF--SHPLFIMFSSGTTGAPKCMVHSAGGTLIQHLKEHLLHGNMTS-- 323
E A + +P HPL+I+++SGTTG PK ++ GG + +LH +M+S
Sbjct: 275 EEMAKAQSHDCVPVLSEHPLYILYTSGTTGLPKGVIRPTGGYAV------MLHWSMSSIY 328
Query: 324 ----SDILLCYTTVGWMMWNWMVSL--LATGAAMVLYDGSPL-VPTPNVLWDLVDRIGIT 376
++ + +GW++ + + L G VLY+G P+ P + ++ G+
Sbjct: 329 GLQPGEVWWAASDLGWVVGHSYICYGPLLHGNTTVLYEGKPVGTPDAGAYFRVLAEHGVA 388
Query: 377 VLVTGAKWLSVLEEKAMKPV--ETHSLQMLHTILSTGSPLKAQSYEYVYRCIKSSIL--L 432
L T + + ++ + +SL T+ G ++ E+ + +L
Sbjct: 389 ALFTAPTAIRAIRQQDPGAALGKQYSLTRFKTLFVAGERCDVETLEWSKNVFRVPVLDHW 448
Query: 433 GSISGGTDIISCFMGHNFSLPVYKGEIQARNLGMAVEAWNEEGKAVWGES-GELVCTKPI 491
G+ I + +G S G+ G V ++ + + G +V P+
Sbjct: 449 WQTETGSPITASCVGLGNSKTPPPGQAGKSVPGYNVMILDDNMQKLKARCLGNIVVKLPL 508
Query: 492 PCQPTHF---WNDENGNKYRKAYFSKFPGIWAHGDYCRINPKTGGIVMLGRSDGTLNPNG 548
P P F W +N ++ YF KFPG + D ++ + G + ++ R D +N G
Sbjct: 509 P--PGAFSGLW--KNQEAFKHLYFEKFPGYYDTMDAGYMD-EEGYLYVMSRVDDVINVAG 563
Query: 549 VRFGSSEIYNIVESFEEVEDSLCVPQYNKYREERVILFLKM-----ASGHAFQPDLVKRI 603
R + I + S V D V + + + + + A+ ++VK +
Sbjct: 564 HRISAGAIEESILSHGTVADCAVVGKEDPLKGHVPLALCVLRKDINATEEQVLEEIVKHV 623
Query: 604 RDAIRMGLSARHVPSLILETKGIPYTLNGKKVEVAVKQIIAGKAVEQGGAFSNP 657
R I + R+ + K +P T +GK A+ I+ GK + +P
Sbjct: 624 RQNIGPVAAFRNA----VFVKQLPKTRSGKIPRSALSAIVNGKPYKITSTIEDP 673
>gi|122937307 acyl-CoA synthetase medium-chain family member 4 [Homo
sapiens]
Length = 580
Score = 65.5 bits (158), Expect = 2e-10
Identities = 116/529 (21%), Positives = 209/529 (39%), Gaps = 61/529 (11%)
Query: 122 GKEEIVKVTFEELRQEVALFAAAMRK-MGVKKGDRVVGYLPNSEHAVEAMLAAASIGAIW 180
GK + VK +F EL A + K G+++GDR+ LP +A G I+
Sbjct: 82 GKGDEVKWSFRELGSLSRKAANVLTKPCGLQRGDRLAVILPRIPEWWLVNVACIRTGIIF 141
Query: 181 SSTSPDFGVNGVLDRFSQIQPKLIFSVEAVVYNGKEHNHMEKLQQVVKGLPDLK-KVVVI 239
+ +L R + K I + E V ++ +V PDLK K++V
Sbjct: 142 MPGTIQLTAKDILYRLRASKAKCIVASEEVA---------PAVESIVLECPDLKTKLLVS 192
Query: 240 P-----YVSSRENIDLSKIPNSVFLDDFLATGTSEQAPQLEFEQLPFSHPLFIMFSSGTT 294
P ++S +E + +S + TG+ E P+ I F+SGTT
Sbjct: 193 PQSWNGWLSFQELFQFASEEHSC-----VETGSQE--------------PMTIYFTSGTT 233
Query: 295 GAPKCMVHSAGGTLIQHLKEHLLHGNMTSSDILLCYTTVGW-------MMWNWMVSLLAT 347
G PK HS I ++ SSDI+ + GW + +W+
Sbjct: 234 GFPKMAQHSQSSLGIGFTLCGRYWLDLKSSDIIWNMSDTGWVKAAIGSVFSSWLCGACVF 293
Query: 348 GAAMVLYDGSPLVPTPNVLWDLVDRIGITVLVTGAKWLSVLEEKAMKPVETHSLQMLHTI 407
M +D + D + IT L + +L +K +K + + L
Sbjct: 294 VHRMAQFD-------TDTFLDTLTTYPITTLCSPPTVYRMLVQKDLK---RYKFKSLRHC 343
Query: 408 LSTGSPLKAQSYEYVYRCIKSSILLGSISGGTDIISCFMGHNFSLPVYKGEIQARNLGMA 467
L+ G PL + E +R +++ + L G T+ + + + G + L
Sbjct: 344 LTGGEPLNPEVLEQ-WR-VQTGLELYEGYGQTE-VGMICANQKGQEIKPGSMGKGMLPYD 400
Query: 468 VEAWNEEGKAV-WGESGELVCTKPIPCQPTHFWNDENGNKYRKAYFSKFPGIWAHGDYCR 526
V+ +E G + G+ GE + + P +P F++ N + A + + GD
Sbjct: 401 VQIIDENGNVLPPGKEGE-IALRLKPTRPFCFFSKYVDNPQKTAATIR-GDFYVTGDR-G 457
Query: 527 INPKTGGIVMLGRSDGTLNPNGVRFGSSEIYNIVESFEEVEDSLCVPQYNKYREERVILF 586
+ G +GR+D + +G R G E+ + + V +S V ++ R E V F
Sbjct: 458 VMDSDGYFWFVGRADDVIISSGYRIGPFEVESALIEHPAVVESAVVSSPDQIRGEVVKAF 517
Query: 587 LKMASG-HAFQPD-LVKRIRDAIRMGLSARHVPSLILETKGIPYTLNGK 633
+ +A+ ++ P+ L ++D ++ + P + + +P T+ GK
Sbjct: 518 VVLAAPFKSYNPEKLTLELQDHVKKSTAPYKYPRKVEFVQELPKTITGK 566
>gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens]
Length = 615
Score = 65.5 bits (158), Expect = 2e-10
Identities = 120/553 (21%), Positives = 230/553 (41%), Gaps = 71/553 (12%)
Query: 112 DRVALYIAREGKEEIVKVTFEELRQEVALFAAAMRKMGVKKGDRVVGYLPNSEHAVEAML 171
+R AL + E V++TF +L++EV A+ + +G+ KGDR+ + PNS V L
Sbjct: 87 EREALVVLHED----VRLTFAQLKEEVDKAASGLLSIGLCKGDRLGMWGPNSYAWVLMQL 142
Query: 172 AAASIGAIWSSTSPDFGVNGVLDRFSQIQPK-LIFSVEAVVYNGKEHNHMEK--LQQVVK 228
A A G I S +P + + ++ K L+F + + +++ ++ K +V
Sbjct: 143 ATAQAGIILVSVNPAYQAMELEYVLKKVGCKALVFPKQ---FKTQQYYNVLKQICPEVEN 199
Query: 229 GLPDLKKVVVIPYVSSRENIDLSKIPNSVFLDDFLATGTSEQ-APQLEFEQ--LPFSHPL 285
P K +P +++ ++D + +P ++ LD+ +A G++ Q QL++ Q L P+
Sbjct: 200 AQPGALKSQRLPDLTTVISVD-APLPGTLLLDEVVAAGSTRQHLDQLQYNQQFLSCHDPI 258
Query: 286 FIMFSSGTTGAPKCMVHSAGGTLIQH--------LKEHLLHGNMTSSDILL-----CYTT 332
I F+SGTTG+PK G TL + L E L T + + Y
Sbjct: 259 NIQFTSGTTGSPK------GATLSHYNIVNNSNILGERLKLHEKTPEQLRMILPNPLYHC 312
Query: 333 VGWMMWNWMVSLLATGAAMVLYDGSPLVPTPNVLWDLVDRIGITVLVTGAKWLSVLEEKA 392
+G + M L GA ++L SP+ L + G + T ++ +L +
Sbjct: 313 LGSVAGTMM--CLMYGATLIL--ASPIFNGKKALEAISRERGTFLYGTPTMFVDILNQ-- 366
Query: 393 MKPVETHSLQMLHTILSTGSPLKAQSYEYVYRCIKSSILLGSISGGTDIISCFMGHNFSL 452
++ + + + GSP + + I L+ + G T+ H
Sbjct: 367 -PDFSSYDISTMCGGVIAGSPAPPELIRAIINKINMKDLVVAY-GTTENSPVTFAH---F 421
Query: 453 PVYKGEIQARNLGMAVEAWNEEGKAVWGESGEL--------VCTKPIPCQPTHFWND--- 501
P E +A ++G + + E + + E+G L +C + C +W +
Sbjct: 422 PEDTVEQKAESVGRIMP--HTEARIMNMEAGTLAKLNTPGELCIRGY-CVMLGYWGEPQK 478
Query: 502 -ENGNKYRKAYFSKFPGIWAHGDYCRINPKTGGIVMLGRSDGTLNPNGVRFGSSEIYNIV 560
E K Y++ GD +N + G ++GRS + G +E+ +
Sbjct: 479 TEEAVDQDKWYWT--------GDVATMN-EQGFCKIVGRSKDMIIRGGENIYPAELEDFF 529
Query: 561 ESFEEVEDSLCVPQYNKYREERVILFLKMASGHAFQPDLVKRIRDAIRMGLSARHVPSLI 620
+ +V++ V + E + +++ G + V+ I+ + +S +P I
Sbjct: 530 HTHPKVQEVQVVGVKDDRMGEEICACIRLKDG---EETTVEEIKAFCKGKISHFKIPKYI 586
Query: 621 LETKGIPYTLNGK 633
+ P T++GK
Sbjct: 587 VFVTNYPLTISGK 599
>gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Homo
sapiens]
Length = 579
Score = 62.8 bits (151), Expect = 1e-09
Identities = 79/353 (22%), Positives = 140/353 (39%), Gaps = 13/353 (3%)
Query: 284 PLFIMFSSGTTGAPKCMVHSAGGTLIQHLKEHLLHGNMTSSDILLCYTTVGWMMWNWMVS 343
PL I F+SGTTGAPK + HS + + +T SDI T GW+ W +
Sbjct: 224 PLAIYFTSGTTGAPKMVEHSQSSYGLGFVASGRRWVALTESDIFWNTTDTGWVKAAWTLF 283
Query: 344 LLATGAAMVLYDGSPLVPTPNVLWDLVDRIGITVLVTGAKWLSVLEEKAMKPVETHSLQM 403
+ + P V V+ + + + IT L +L + + + Q
Sbjct: 284 SAWPNGSCIFVHELPRVDA-KVILNTLSKFPITTLCCVPTIFRLL---VQEDLTRYQFQS 339
Query: 404 LHTILSTGSPLKAQSYEYVYRCIKSSILLGSISGGTDIISCFMGHNFSLPVYKGEIQARN 463
L L+ G L E + G T +I + + + G + +
Sbjct: 340 LRHCLTGGEALNPDVREKWKHQTGVELYEGYGQSETVVI---CANPKGMKIKSGSMGKAS 396
Query: 464 LGMAVEAWNEEGKAV-WGESGELVCTKPIPCQPTHFWNDENGNKYRKAYFSKFPGIWAHG 522
V+ ++EG + GE G V + P +P F+N N K S+ + G
Sbjct: 397 PPYDVQIVDDEGNVLPPGEEGN-VAVRIRPTRPFCFFNCYLDNP-EKTAASEQGDFYITG 454
Query: 523 DYCRINPKTGGIVMLGRSDGTLNPNGVRFGSSEIYNIVESFEEVEDSLCVPQYNKYREER 582
D R++ K G +GR+D +N + R G E+ + + V +S V + R E
Sbjct: 455 DRARMD-KDGYFWFMGRNDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEV 513
Query: 583 VILFLKMASGH-AFQPD-LVKRIRDAIRMGLSARHVPSLILETKGIPYTLNGK 633
V F+ + + + P+ L + +++ ++ + P + +P T++GK
Sbjct: 514 VKAFIVLTPAYSSHDPEALTRELQEHVKRVTAPYKYPRKVAFVSELPKTVSGK 566
>gi|157311624 acyl-CoA synthetase medium-chain family member 2B
[Homo sapiens]
Length = 577
Score = 56.2 bits (134), Expect = 9e-08
Identities = 125/577 (21%), Positives = 233/577 (40%), Gaps = 70/577 (12%)
Query: 79 EVVDTSKGIADVPEWFKGSRLNYAENLLRH--------KENDRVALYIAREGKEEIVKVT 130
++V G +VP ++ N+A ++L H K AL+ GK + +
Sbjct: 29 QLVSLQWGHQEVP-----AKFNFASDVLDHWADMEKAGKRLPSPALWWVN-GKGKELMWN 82
Query: 131 FEELRQEVALFAAAMR-KMGVKKGDRVVGYLPNSEHAVEAMLAAASIGAIWSSTSPDFGV 189
F EL + A + G+++GDRV LP +L G I+ +
Sbjct: 83 FRELSENSQQAANILSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQMKS 142
Query: 190 NGVLDRFSQIQPKLIFSVEAVVYNGKEHNHMEKLQQVVKGLPDLKKVVVIPYVSSRENID 249
+L R + K I + + V+ +++ V P L+ +++ S ++
Sbjct: 143 TDILYRLQMSKAKAIVAGDEVI---------QEVDTVASECPSLRIKLLVSEKSCDGWLN 193
Query: 250 LSKIPNSVFLDDFLATGTSEQAPQLEFEQLPFSHPLFIMFSSGTTGAPKCMVHSAGGTLI 309
K+ N S++A I F+SGT+G PK HS +
Sbjct: 194 FKKLLNEASTTHHCVETGSQEASA-------------IYFTSGTSGLPKMAEHSYSSLGL 240
Query: 310 QHLKEHLLHGNMTSSDILLCYTTVGWMMWNWMVSLLAT---GAAMVLYDGSPLVPT--PN 364
+ + G + +SDI+ + GW++ N + SLL + GA ++ L+P P
Sbjct: 241 KAKMDAGWTG-LQASDIMWTISDTGWIL-NILGSLLESWTLGACTFVH----LLPKFDPL 294
Query: 365 VLWDLVDRIGITVLVTGAKWLSVLEEKAMKPVETHSLQMLHTILSTGSPLKAQSYEYVYR 424
V+ + I ++ GA V + + ++ L L+ G L ++ E +R
Sbjct: 295 VILKTLSSYPIKSMM-GAP--IVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLEN-WR 350
Query: 425 CIKSSILLGSISGGTDI-ISCFMGHNFSL-PVYKGEIQARNLGMAVEAWNEEGKAVW-GE 481
++ + + G T+ ++C + + P Y G + V+ +++G + G
Sbjct: 351 A-QTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASC---YDVQVIDDKGNVLPPGT 406
Query: 482 SGEL-VCTKPIPCQPTHFWND--ENGNKYRKAYFSKFPGIWAHGDYCRINPKTGGIVMLG 538
G++ + KPI +P ++ EN +K F W GD I + G +G
Sbjct: 407 EGDIGIRVKPI--RPIGIFSGYVENPDKTAANIRGDF---WLLGDR-GIKDEDGYFQFMG 460
Query: 539 RSDGTLNPNGVRFGSSEIYNIVESFEEVEDSLCVPQYNKYREERVILFLKMASGH-AFQP 597
R+D +N +G R G SE+ N + V ++ + + R E V F+ +AS + P
Sbjct: 461 RADDIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSHDP 520
Query: 598 D-LVKRIRDAIRMGLSARHVPSLILETKGIPYTLNGK 633
+ L K ++ ++ + P I +P T+ GK
Sbjct: 521 EQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGK 557
>gi|157311622 acyl-CoA synthetase medium-chain family member 2B
[Homo sapiens]
Length = 577
Score = 56.2 bits (134), Expect = 9e-08
Identities = 125/577 (21%), Positives = 233/577 (40%), Gaps = 70/577 (12%)
Query: 79 EVVDTSKGIADVPEWFKGSRLNYAENLLRH--------KENDRVALYIAREGKEEIVKVT 130
++V G +VP ++ N+A ++L H K AL+ GK + +
Sbjct: 29 QLVSLQWGHQEVP-----AKFNFASDVLDHWADMEKAGKRLPSPALWWVN-GKGKELMWN 82
Query: 131 FEELRQEVALFAAAMR-KMGVKKGDRVVGYLPNSEHAVEAMLAAASIGAIWSSTSPDFGV 189
F EL + A + G+++GDRV LP +L G I+ +
Sbjct: 83 FRELSENSQQAANILSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQMKS 142
Query: 190 NGVLDRFSQIQPKLIFSVEAVVYNGKEHNHMEKLQQVVKGLPDLKKVVVIPYVSSRENID 249
+L R + K I + + V+ +++ V P L+ +++ S ++
Sbjct: 143 TDILYRLQMSKAKAIVAGDEVI---------QEVDTVASECPSLRIKLLVSEKSCDGWLN 193
Query: 250 LSKIPNSVFLDDFLATGTSEQAPQLEFEQLPFSHPLFIMFSSGTTGAPKCMVHSAGGTLI 309
K+ N S++A I F+SGT+G PK HS +
Sbjct: 194 FKKLLNEASTTHHCVETGSQEASA-------------IYFTSGTSGLPKMAEHSYSSLGL 240
Query: 310 QHLKEHLLHGNMTSSDILLCYTTVGWMMWNWMVSLLAT---GAAMVLYDGSPLVPT--PN 364
+ + G + +SDI+ + GW++ N + SLL + GA ++ L+P P
Sbjct: 241 KAKMDAGWTG-LQASDIMWTISDTGWIL-NILGSLLESWTLGACTFVH----LLPKFDPL 294
Query: 365 VLWDLVDRIGITVLVTGAKWLSVLEEKAMKPVETHSLQMLHTILSTGSPLKAQSYEYVYR 424
V+ + I ++ GA V + + ++ L L+ G L ++ E +R
Sbjct: 295 VILKTLSSYPIKSMM-GAP--IVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLEN-WR 350
Query: 425 CIKSSILLGSISGGTDI-ISCFMGHNFSL-PVYKGEIQARNLGMAVEAWNEEGKAVW-GE 481
++ + + G T+ ++C + + P Y G + V+ +++G + G
Sbjct: 351 A-QTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASC---YDVQVIDDKGNVLPPGT 406
Query: 482 SGEL-VCTKPIPCQPTHFWND--ENGNKYRKAYFSKFPGIWAHGDYCRINPKTGGIVMLG 538
G++ + KPI +P ++ EN +K F W GD I + G +G
Sbjct: 407 EGDIGIRVKPI--RPIGIFSGYVENPDKTAANIRGDF---WLLGDR-GIKDEDGYFQFMG 460
Query: 539 RSDGTLNPNGVRFGSSEIYNIVESFEEVEDSLCVPQYNKYREERVILFLKMASGH-AFQP 597
R+D +N +G R G SE+ N + V ++ + + R E V F+ +AS + P
Sbjct: 461 RADDIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSHDP 520
Query: 598 D-LVKRIRDAIRMGLSARHVPSLILETKGIPYTLNGK 633
+ L K ++ ++ + P I +P T+ GK
Sbjct: 521 EQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGK 557
>gi|58082049 acyl-CoA synthetase medium-chain family member 2A [Homo
sapiens]
Length = 577
Score = 55.8 bits (133), Expect = 1e-07
Identities = 119/575 (20%), Positives = 230/575 (40%), Gaps = 66/575 (11%)
Query: 79 EVVDTSKGIADVPEWFKGSRLNYAENLLRH--------KENDRVALYIAREGKEEIVKVT 130
++V G +VP ++ N+A ++L H K AL+ GK + +
Sbjct: 29 QLVSLQWGHQEVP-----AKFNFASDVLDHWADMEKAGKRLPSPALWWVN-GKGKELMWN 82
Query: 131 FEELRQEVALFAAAMR-KMGVKKGDRVVGYLPNSEHAVEAMLAAASIGAIWSSTSPDFGV 189
F EL + A + G+++GDRV LP +L G I+ +
Sbjct: 83 FRELSENSQQAANVLSGACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMPGTIQMKS 142
Query: 190 NGVLDRFSQIQPKLIFSVEAVVYNGKEHNHMEKLQQVVKGLPDLKKVVVIPYVSSRENID 249
+L R + K I + + V+ +++ V P L+ +++ S ++
Sbjct: 143 TDILYRLQMSKAKAIVAGDEVI---------QEVDTVASECPSLRIKLLVSEKSCDGWLN 193
Query: 250 LSKIPNSVFLDDFLATGTSEQAPQLEFEQLPFSHPLFIMFSSGTTGAPKCMVHSAGGTLI 309
K+ N S++A I F+SGT+G PK HS +
Sbjct: 194 FKKLLNEASTTHHCVETGSQEASA-------------IYFTSGTSGLPKMAEHSYSSLGL 240
Query: 310 QHLKEHLLHGNMTSSDILLCYTTVGWMMWNWMVSLL---ATGAAMVLYDGSPLVPT--PN 364
+ + G + +SDI+ + GW++ N + SL+ A GA ++ L+P P
Sbjct: 241 KAKMDAGWTG-LQASDIMWTISDTGWIL-NILCSLMEPWALGACTFVH----LLPKFDPL 294
Query: 365 VLWDLVDRIGITVLVTGAKWLSVLEEKAMKPVETHSLQMLHTILSTGSPLKAQSYEYVYR 424
V+ + I ++ +L ++ + + LQ T+ + P +++
Sbjct: 295 VILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCVTVGESLLPETLENWR---- 350
Query: 425 CIKSSILLGSISGGTDI-ISCFMGHNFSL-PVYKGEIQARNLGMAVEAWNEEGKAVW-GE 481
++ + + G T+ ++C + + P Y G + V+ +++G + G
Sbjct: 351 -AQTGLDIRESYGQTETGLTCMVSKTMKIKPGYMGTAASC---YDVQIIDDKGNVLPPGT 406
Query: 482 SGEL-VCTKPIPCQPTHFWNDENGNKYRKAYFSKFPGIWAHGDYCRINPKTGGIVMLGRS 540
G++ + KPI +P ++ N + A + W GD I + G +GR+
Sbjct: 407 EGDIGIRVKPI--RPIGIFSGYVDNPDKTAANIR-GDFWLLGDR-GIKDEDGYFQFMGRA 462
Query: 541 DGTLNPNGVRFGSSEIYNIVESFEEVEDSLCVPQYNKYREERVILFLKMASGH-AFQPD- 598
D +N +G R G SE+ N + V ++ + + R E V F+ +AS + P+
Sbjct: 463 DDIINSSGYRIGPSEVENALMEHPAVVETAVISSPDPVRGEVVKAFVVLASQFLSHDPEQ 522
Query: 599 LVKRIRDAIRMGLSARHVPSLILETKGIPYTLNGK 633
L K ++ ++ + P I +P T+ GK
Sbjct: 523 LTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGK 557
>gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase
ACSM2B, mitochondrial isoform 2 [Homo sapiens]
Length = 571
Score = 50.8 bits (120), Expect = 4e-06
Identities = 124/577 (21%), Positives = 228/577 (39%), Gaps = 76/577 (13%)
Query: 79 EVVDTSKGIADVPEWFKGSRLNYAENLLRH--------KENDRVALYIAREGKEEIVKVT 130
++V G +VP ++ N+A ++L H K AL+ GK + +
Sbjct: 29 QLVSLQWGHQEVP-----AKFNFASDVLDHWADMEKAGKRLPSPALWWVN-GKGKELMWN 82
Query: 131 FEELRQEVALFAAAMR-KMGVKKGDRVVGYLPNSEHAVEAMLAAASIGAIWSSTSPDFGV 189
F EL + A + G+++GDRV LP +L G I+ +
Sbjct: 83 FRELSENSQQAANVLSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQMKS 142
Query: 190 NGVLDRFSQIQPKLIFSVEAVVYNGKEHNHMEKLQQVVKGLPDLKKVVVIPYVSSRENID 249
+L R + K I + + V+ +++ V P L+ +++ S ++
Sbjct: 143 TDILYRLQMSKAKAIVAGDEVI---------QEVDTVASECPSLRIKLLVSEKSCDGWLN 193
Query: 250 LSKIPNSVFLDDFLATGTSEQAPQLEFEQLPFSHPLFIMFSSGTTGAPKCMVHSAGGTLI 309
K+ N S++A I F+SGT+G PK HS
Sbjct: 194 FKKLLNEASTTHHCVETGSQEASA-------------IYFTSGTSGLPKMAEHSYSSL-- 238
Query: 310 QHLKEHLLHG--NMTSSDILLCYTTVGWMMWNWMVSLLAT---GAAMVLYDGSPLVP--T 362
LK + G + +SDI+ + GW++ N + SLL + GA ++ L+P
Sbjct: 239 -GLKAKMDAGWTGLQASDIMWTISDTGWIL-NILGSLLESWTLGACTFVH----LLPKFD 292
Query: 363 PNVLWDLVDRIGITVLVTGAKWLSVLEEKAMKPVETHSLQMLHTILSTGSPLKAQSYEYV 422
P V+ + I ++ GA V + + ++ L L+ G L ++ E
Sbjct: 293 PLVILKTLSSYPIKSMM-GAP--IVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLEN- 348
Query: 423 YRCIKSSILLGSISGGTDI-ISCFMGHNFSLPVYKGEIQARNLGMAVEAWNEEGKA-VWG 480
+R ++ + + G T+ ++C + +I+ +G A ++ + A V G
Sbjct: 349 WRA-QTGLDIREFYGQTETGLTCMVSKTM-------KIKPGYMGTAASCYDVQVIAFVHG 400
Query: 481 --ESGELVCTKPIPCQPTHFWNDENGNKYRKAYFSKFPGIWAHGDYCRINPKTGGIVMLG 538
+G+L + + + EN +K F W GD I + G +G
Sbjct: 401 SPRAGDLGFAGTMTL--SFCGHQENPDKTAANIRGDF---WLLGDR-GIKDEDGYFQFMG 454
Query: 539 RSDGTLNPNGVRFGSSEIYNIVESFEEVEDSLCVPQYNKYREERVILFLKMASGH-AFQP 597
R+D +N +G R G SE+ N + V ++ + + R E V F+ +AS + P
Sbjct: 455 RADDIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSHDP 514
Query: 598 D-LVKRIRDAIRMGLSARHVPSLILETKGIPYTLNGK 633
+ L K ++ ++ + P I +P T+ GK
Sbjct: 515 EQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGK 551
>gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase
ACSM2B, mitochondrial isoform 1 [Homo sapiens]
Length = 571
Score = 50.8 bits (120), Expect = 4e-06
Identities = 124/577 (21%), Positives = 228/577 (39%), Gaps = 76/577 (13%)
Query: 79 EVVDTSKGIADVPEWFKGSRLNYAENLLRH--------KENDRVALYIAREGKEEIVKVT 130
++V G +VP ++ N+A ++L H K AL+ GK + +
Sbjct: 29 QLVSLQWGHQEVP-----AKFNFASDVLDHWADMEKAGKRLPSPALWWVN-GKGKELMWN 82
Query: 131 FEELRQEVALFAAAMR-KMGVKKGDRVVGYLPNSEHAVEAMLAAASIGAIWSSTSPDFGV 189
F EL + A + G+++GDRV LP +L G I+ +
Sbjct: 83 FRELSENSQQAANVLSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQMKS 142
Query: 190 NGVLDRFSQIQPKLIFSVEAVVYNGKEHNHMEKLQQVVKGLPDLKKVVVIPYVSSRENID 249
+L R + K I + + V+ +++ V P L+ +++ S ++
Sbjct: 143 TDILYRLQMSKAKAIVAGDEVI---------QEVDTVASECPSLRIKLLVSEKSCDGWLN 193
Query: 250 LSKIPNSVFLDDFLATGTSEQAPQLEFEQLPFSHPLFIMFSSGTTGAPKCMVHSAGGTLI 309
K+ N S++A I F+SGT+G PK HS
Sbjct: 194 FKKLLNEASTTHHCVETGSQEASA-------------IYFTSGTSGLPKMAEHSYSSL-- 238
Query: 310 QHLKEHLLHG--NMTSSDILLCYTTVGWMMWNWMVSLLAT---GAAMVLYDGSPLVP--T 362
LK + G + +SDI+ + GW++ N + SLL + GA ++ L+P
Sbjct: 239 -GLKAKMDAGWTGLQASDIMWTISDTGWIL-NILGSLLESWTLGACTFVH----LLPKFD 292
Query: 363 PNVLWDLVDRIGITVLVTGAKWLSVLEEKAMKPVETHSLQMLHTILSTGSPLKAQSYEYV 422
P V+ + I ++ GA V + + ++ L L+ G L ++ E
Sbjct: 293 PLVILKTLSSYPIKSMM-GAP--IVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLEN- 348
Query: 423 YRCIKSSILLGSISGGTDI-ISCFMGHNFSLPVYKGEIQARNLGMAVEAWNEEGKA-VWG 480
+R ++ + + G T+ ++C + +I+ +G A ++ + A V G
Sbjct: 349 WRA-QTGLDIREFYGQTETGLTCMVSKTM-------KIKPGYMGTAASCYDVQVIAFVHG 400
Query: 481 --ESGELVCTKPIPCQPTHFWNDENGNKYRKAYFSKFPGIWAHGDYCRINPKTGGIVMLG 538
+G+L + + + EN +K F W GD I + G +G
Sbjct: 401 SPRAGDLGFAGTMTL--SFCGHQENPDKTAANIRGDF---WLLGDR-GIKDEDGYFQFMG 454
Query: 539 RSDGTLNPNGVRFGSSEIYNIVESFEEVEDSLCVPQYNKYREERVILFLKMASGH-AFQP 597
R+D +N +G R G SE+ N + V ++ + + R E V F+ +AS + P
Sbjct: 455 RADDIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSHDP 514
Query: 598 D-LVKRIRDAIRMGLSARHVPSLILETKGIPYTLNGK 633
+ L K ++ ++ + P I +P T+ GK
Sbjct: 515 EQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGK 551
>gi|115511026 acyl-CoA synthetase medium-chain family member 1 [Homo
sapiens]
Length = 577
Score = 48.1 bits (113), Expect = 3e-05
Identities = 92/516 (17%), Positives = 193/516 (37%), Gaps = 35/516 (6%)
Query: 122 GKEEIVKVTFEELRQEVALFAAAMRKM-GVKKGDRVVGYLPNSEHAVEAMLAAASIGAIW 180
G+ + VK +F E+ A + G+++GD + LP + G I+
Sbjct: 79 GQGDEVKWSFREMGDLTRRVANVFTQTCGLQQGDHLALMLPRVPEWWLVAVGCMRTGIIF 138
Query: 181 SSTSPDFGVNGVLDRFSQIQPKLIFSVEAVVYNGKEHNHMEKLQQVVKGLPDLKKVVVIP 240
+ +L R + K I +++A+ ++ + P LK +++
Sbjct: 139 IPATILLKAKDILYRLQLSKAKGIVTIDALA---------SEVDSIASQCPSLKTKLLVS 189
Query: 241 YVSSRENIDLSKIPNSVFLDDFLATGTSEQAPQLEFEQLPFSHPLFIMFSSGTTGAPKCM 300
S +D + S +P+ + P+ I F+SGTTG PK
Sbjct: 190 DHSREGWLDFRSLVKSA-------------SPEHTCVKSKTLDPMVIFFTSGTTGFPKMA 236
Query: 301 VHSAGGTLIQHLKEHLLHGNMTSSDILLCYTTVGWMMWN-WMVSLLATGAAMVLYDGSPL 359
HS G L ++ +SD+ C + GW++ W + T V P
Sbjct: 237 KHSHGLALQPSFPGSRKLRSLKTSDVSWCLSDSGWIVATIWTLVEPWTAGCTVFIHHLPQ 296
Query: 360 VPTPNVLWDLVDRIGITVLVTGAKWLSVLEEKAMKPVETHSLQMLHTILSTGSPLKAQSY 419
T ++ L+ + I + ++ ++ + +L+ +T P + +
Sbjct: 297 FDTKVIIQTLL-KYPINHFWGVSSIYRMILQQDFTSIRFPALEHCYTGGEVVLPKDQEEW 355
Query: 420 EYVYRCIKSSILLGSISGGTDIISCFMGHNFSLPVYKGEIQARNLGMAVEAWNEEGKAVW 479
+ ++ +LL G ++ + + + G + V+ +++G +
Sbjct: 356 KR-----RTGLLLYENYGQSE-TGLICATYWGMKIKPGFMGKATPPYDVQVIDDKGSILP 409
Query: 480 GESGELVCTKPIPCQPTHFWNDENGNKYRKAYFSKFPGIWAHGDYCRINPKTGGIVMLGR 539
+ + + P +P + G+ + A + + GD +++ + G I LGR
Sbjct: 410 PNTEGNIGIRIKPVRPVSLFMCYEGDPEKTAKV-ECGDFYNTGDRGKMD-EEGYICFLGR 467
Query: 540 SDGTLNPNGVRFGSSEIYNIVESFEEVEDSLCVPQYNKYREERVILFLKMASGHAF--QP 597
SD +N +G R G +E+ + + V +S V + R E V F+ + +
Sbjct: 468 SDDIINASGYRIGPAEVESALVEHPAVAESAVVGSPDPIRGEVVKAFIVLTPQFLSHDKD 527
Query: 598 DLVKRIRDAIRMGLSARHVPSLILETKGIPYTLNGK 633
L K ++ ++ + P + +P T+ GK
Sbjct: 528 QLTKELQQHVKSVTAPYKYPRKVEFVSELPKTITGK 563
>gi|42544132 SA hypertension-associated homolog isoform 1 [Homo
sapiens]
Length = 586
Score = 47.4 bits (111), Expect = 4e-05
Identities = 109/563 (19%), Positives = 215/563 (38%), Gaps = 63/563 (11%)
Query: 90 VPEWFKGSRLNYAENLLRH---------KENDRVALYIAREGKEEIVKVTFEELRQEVAL 140
+PE+F N+A+++L K ++ +I R G+E ++ +FEEL
Sbjct: 54 IPEYF-----NFAKDVLDQWTDKEKAGKKPSNPAFWWINRNGEE--MRWSFEELGSLSRK 106
Query: 141 FAAAMRKM-GVKKGDRVVGYLPNSEHAVEAMLAAASIGAIWSSTSPDFGVNGVLDRFSQI 199
FA + + +++GDRV+ LP A +A G + + +L R
Sbjct: 107 FANILSEACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSS 166
Query: 200 QPKLIFSVEAVVYNGKEHNHMEKLQQVVKGLPDLKKVVVIPYVSSRENIDLSKIPNSVFL 259
+ I + + + + V +L +++ +SRE K
Sbjct: 167 KANCIITNDVLA---------PAVDAVASKCENLHSKLIVSE-NSREGWGNLKELMKHAS 216
Query: 260 DDFLATGTSEQAPQLEFEQLPFSHPLFIMFSSGTTGAPKCMVHSAGGTLIQHLKEHLLHG 319
D T + + I F+SGT+G PK H+ +
Sbjct: 217 DSHTCVKTKH------------NEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGRFWL 264
Query: 320 NMTSSDILLCYTTVGWMM--WNWMVSLLATGAAMVLYDGSPLVPTPNVLWDLVDRIGITV 377
++T SD++ + GW W+ + S GA + + PT + + + ITV
Sbjct: 265 DLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACVFTHHLPRFEPTS--ILQTLSKYPITV 322
Query: 378 LVTGAKWLSVLEEKAMKPVETHSLQMLHTILSTGSPLKAQSYEYVYRCIKSSILLGSISG 437
+ +V + ++ + L +S G P+ E K+ + + G
Sbjct: 323 FCSAP---TVYRMLVQNDITSYKFKSLKHCVSAGEPITPDVTEKWRN--KTGLDIYEGYG 377
Query: 438 GTDIISCFMGHNFSLPVYKGEIQARNLGMAVEAWNEEGKAVW-GESGELVCTKPIPCQP- 495
T+ + G+ + + G + + V+ + G + G+ G+ + + +P +P
Sbjct: 378 QTETV-LICGNFKGMKIKPGSMGKPSPAFDVKIVDVNGNVLPPGQEGD-IGIQVLPNRPF 435
Query: 496 ---THFWNDENGNKYRKAYFSKFPGIWAHGDYCRINPKTGGIVMLGRSDGTLNPNGVRFG 552
TH+ +N +K F + GD ++ K G + R+D + +G R G
Sbjct: 436 GLFTHYV--DNPSKTASTLRGNF---YITGDRGYMD-KDGYFWFVARADDVILSSGYRIG 489
Query: 553 SSEIYNIVESFEEVEDSLCVPQYNKYREERVILFLKMASGHAF--QPDLVKRIRDAIRMG 610
E+ N + V +S V + R E V F+ + + Q L+K I++ ++
Sbjct: 490 PFEVENALNEHPSVAESAVVSSPDPIRGEVVKAFVVLNPDYKSHDQEQLIKEIQEHVKKT 549
Query: 611 LSARHVPSLILETKGIPYTLNGK 633
+ P + + +P T++GK
Sbjct: 550 TAPYKYPRKVEFIQELPKTISGK 572
>gi|45580730 aminoadipate-semialdehyde dehydrogenase [Homo sapiens]
Length = 1098
Score = 40.8 bits (94), Expect = 0.004
Identities = 79/377 (20%), Positives = 148/377 (39%), Gaps = 49/377 (12%)
Query: 275 EFEQLPFSHPL-FIMFSSGTTGAPKCMVHSAGGTLIQHLKEHLLHGNMTSSDILLCYTTV 333
E L H L +++ +SGTTG PK +V ++ +++ + ++T D+L + +
Sbjct: 182 EHMDLRLKHCLAYVLHTSGTTGIPK-IVRVPHKCIVPNIQHFRVLFDITQEDVLFLASPL 240
Query: 334 GWMMWNWMVSL-LATGAAMVLYDGSPLVPTPNVLWDLVDRIGITVLVTGAKWLSVLEEKA 392
+ + L L++GA++++ S + + L +TVL L +
Sbjct: 241 TFDPSVVEIFLALSSGASLLIVPTSVKLLPSKLASVLFSHHRVTVLQATPTLLRRFGSQL 300
Query: 393 MKPVETHSLQMLHTILSTGSPLKAQSYEYVYRCIKSSILLGSISGGTDIISCFMGHNF-- 450
+K + L + G + + +R + + ++ G T++ S +
Sbjct: 301 IKSTVLSATTSLRVLALGGEAFPSLTVLRSWRGEGNKTQIFNVYGITEVSSWATIYRIPE 360
Query: 451 ---------SLPVYKGEIQARNLGMAVEAWNEEGKAVWGESGELVCTKPIPCQPTHFWND 501
LPV G LG VE + G + SG++
Sbjct: 361 KTLNSTLKCELPVQLG---FPLLGTVVEVRDTNGFTIQEGSGQVFL-------------- 403
Query: 502 ENGNKYRKAYFSK-----FPGIWAHGDYCRINPKTGGIVMLGRSDGTLNPNGVRFGSSEI 556
G + R + + A GD+ + K G I LGR D + +G R +
Sbjct: 404 --GGRNRVCFLDDEVTVPLGTMRATGDFVTV--KDGEIFFLGRKDSQIKRHGKRLNIELV 459
Query: 557 YNIVESFEEVEDSLCVPQYNKYREERVILFLKMASGHAFQPDLVKRIRDAIRMGLSARHV 616
+ E ++VE S V YN +E++ILF M S A + + I ++ L + V
Sbjct: 460 QQVAEELQQVE-SCAVTWYN---QEKLILF--MVSKDA---SVKEYIFKELQKYLPSHAV 510
Query: 617 PSLILETKGIPYTLNGK 633
P ++ +P+T +GK
Sbjct: 511 PDELVLIDSLPFTSHGK 527
>gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Homo
sapiens]
Length = 480
Score = 37.7 bits (86), Expect = 0.035
Identities = 64/324 (19%), Positives = 124/324 (38%), Gaps = 41/324 (12%)
Query: 118 IAREGKEEIVKVTFEELRQEVALFAAAMRKM-GVKKGDRVVGYLPNSEHAVEAMLAAASI 176
++ +G+E+ K +FE + Q A+ + + GDR++ LP + A LA +
Sbjct: 77 VSAKGEED--KWSFERMTQLSKKAASILSDTCALSHGDRLMIILPPTPEAYWICLACVRL 134
Query: 177 GAIWSSTSPDFGVNGVLDRFSQIQPKLIFSVEAVVYNGKEHNHMEKLQQVVKGLPDLKKV 236
G + SP + + + + I + EA+ + V P LK
Sbjct: 135 GITFVPGSPQLTAKKIRYQLRMSKAQCIVANEAMA---------PVVNSAVSDCPTLKTK 185
Query: 237 VVIPYVSSRENIDLSKIPNSVFLDDFLATGTSEQAPQLEFEQLPFSHPLFIMFSSGTTGA 296
+++ S +D K+ P+ + + P+ I F+ GTTGA
Sbjct: 186 LLVSDKSYDGWLDFKKL-------------IQVAPPKQTYMRTKSQDPMAIFFTKGTTGA 232
Query: 297 PKCMVHSAGGTLIQHLKEHLLHGNMTSSDILLCYTTVGWMMWNWMVSLLATGAAM-VLYD 355
PK + +S G + + ++ +D+L W + + L+ A + +
Sbjct: 233 PKMVEYSQYGLGMGFSQASRRWMDLQPTDVL-------WSLGDAFGGSLSLSAVLGTWFQ 285
Query: 356 GSPL----VPT--PNVLWDLVDRIGITVLVTGAKWLSVLEEKAMKPVETHSLQMLHTILS 409
G+ + +PT P + +++ R IT L + L + K ++ + L ++
Sbjct: 286 GACVFLCHMPTFCPETVLNVLSRFPITTLSANPEMYQELLQH--KCFTSYRFKSLKQCVA 343
Query: 410 TGSPLKAQSYEYVYRCIKSSILLG 433
G P+ E R K I G
Sbjct: 344 AGGPISPGVIEDWKRITKLDIYEG 367
>gi|227499619 solute carrier family 27 (fatty acid transporter),
member 2 isoform 1 [Homo sapiens]
Length = 620
Score = 37.0 bits (84), Expect = 0.059
Identities = 46/175 (26%), Positives = 69/175 (39%), Gaps = 27/175 (15%)
Query: 148 MGVKKGDRVVGYLPNSEHAVEAMLAAASIGAIWSSTSPDFGVNGVLDRFSQIQPKLIFSV 207
+G+++GD V + N V L +G + + + +L F K++
Sbjct: 99 LGLRQGDCVALLMGNEPAYVWLWLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVLLV- 157
Query: 208 EAVVYNGKEHNHMEKLQQVVKG-LPDLKKV-VVIPYVSSRENIDLSKIPNSVFLDDFLAT 265
+LQ V+ LP LKK V I YVS N D FLD
Sbjct: 158 ------------SPELQAAVEEILPSLKKDDVSIYYVSRTSNTD----GIDSFLDKVDEV 201
Query: 266 GTSEQAPQLEFEQLPFSHPLFIMFSSGTTGAPKCMV-------HSAGGTLIQHLK 313
T E P+ ++ FS P +++SGTTG PK + + G T + LK
Sbjct: 202 ST-EPIPESWRSEVTFSTPALYIYTSGTTGLPKAAMITHQRIWYGTGLTFVSGLK 255
>gi|27477105 lipidosin [Homo sapiens]
Length = 724
Score = 36.6 bits (83), Expect = 0.077
Identities = 48/196 (24%), Positives = 81/196 (41%), Gaps = 26/196 (13%)
Query: 109 KENDRVALYIAREGKEEIVKVTFEELRQEVALFAAAMRKMGVKKGDRVVGYLPNSEH--- 165
K D +AL R+ K E + + L A A K+G+K+ V NS
Sbjct: 115 KYGDLIALGFKRQDKWEHISYSQYYLLARRA--AKGFLKLGLKQAHSVAILGFNSPEWFF 172
Query: 166 -AVEAMLAAASIGAIWSSTSPDFGVNGVLDRFSQIQPKLIFSVEAVVYNGKEHNHMEKLQ 224
AV + A + I++++SP+ + + A V +EK+
Sbjct: 173 SAVGTVFAGGIVTGIYTTSSPE------------ACQYIAYDCCANVIMVDTQKQLEKIL 220
Query: 225 QVVKGLPDLKKVVVIPYVSSRENIDLSKIPNSVFLDDFLATGTS--EQAPQLEFEQLPFS 282
++ K LP LK VV+ Y N K+ N +++F+ G E+A + +
Sbjct: 221 KIWKQLPHLKAVVI--YKEPPPN----KMANVYTMEEFMELGNEVPEEALDAIIDTQQPN 274
Query: 283 HPLFIMFSSGTTGAPK 298
++++SGTTG PK
Sbjct: 275 QCCVLVYTSGTTGNPK 290
>gi|206597513 ArfGAP with RhoGAP domain, ankyrin repeat and PH
domain 1 isoform a [Homo sapiens]
Length = 1205
Score = 35.0 bits (79), Expect = 0.23
Identities = 28/109 (25%), Positives = 44/109 (40%), Gaps = 1/109 (0%)
Query: 310 QHLKEHLLHGNMTSSDILLCYTTVGWMMWNWMVSLLATGAAMVLYDGSPLVPTPNVLWDL 369
++ + H L GN D LC + +LL GA + + G P PTP L +
Sbjct: 403 KYRRYHPLFGNQEELDKALCAAVTTTDLAETQ-ALLGCGAGINCFSGDPEAPTPLALAEQ 461
Query: 370 VDRIGITVLVTGAKWLSVLEEKAMKPVETHSLQMLHTILSTGSPLKAQS 418
+ + + V +MKP+E H +L T+ +G K S
Sbjct: 462 AGQTLQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTAS 510
>gi|92091600 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain
1 isoform c [Homo sapiens]
Length = 1450
Score = 35.0 bits (79), Expect = 0.23
Identities = 28/109 (25%), Positives = 44/109 (40%), Gaps = 1/109 (0%)
Query: 310 QHLKEHLLHGNMTSSDILLCYTTVGWMMWNWMVSLLATGAAMVLYDGSPLVPTPNVLWDL 369
++ + H L GN D LC + +LL GA + + G P PTP L +
Sbjct: 648 KYRRYHPLFGNQEELDKALCAAVTTTDLAETQ-ALLGCGAGINCFSGDPEAPTPLALAEQ 706
Query: 370 VDRIGITVLVTGAKWLSVLEEKAMKPVETHSLQMLHTILSTGSPLKAQS 418
+ + + V +MKP+E H +L T+ +G K S
Sbjct: 707 AGQTLQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTAS 755
>gi|227499621 solute carrier family 27 (fatty acid transporter),
member 2 isoform 2 [Homo sapiens]
Length = 567
Score = 33.9 bits (76), Expect = 0.50
Identities = 41/151 (27%), Positives = 61/151 (40%), Gaps = 20/151 (13%)
Query: 148 MGVKKGDRVVGYLPNSEHAVEAMLAAASIGAIWSSTSPDFGVNGVLDRFSQIQPKLIFSV 207
+G+++GD V + N V L +G + + + +L F K++
Sbjct: 99 LGLRQGDCVALLMGNEPAYVWLWLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVLLV- 157
Query: 208 EAVVYNGKEHNHMEKLQQVVKG-LPDLKKV-VVIPYVSSRENIDLSKIPNSVFLDDFLAT 265
+LQ V+ LP LKK V I YVS N D FLD
Sbjct: 158 ------------SPELQAAVEEILPSLKKDDVSIYYVSRTSNTD----GIDSFLDKVDEV 201
Query: 266 GTSEQAPQLEFEQLPFSHPLFIMFSSGTTGA 296
T E P+ ++ FS P +++SGTTGA
Sbjct: 202 ST-EPIPESWRSEVTFSTPALYIYTSGTTGA 231
>gi|62865631 solute carrier family 27 (fatty acid transporter),
member 6 [Homo sapiens]
Length = 619
Score = 33.9 bits (76), Expect = 0.50
Identities = 51/249 (20%), Positives = 89/249 (35%), Gaps = 44/249 (17%)
Query: 61 FWAEFWKFSGIVFSRVYDEVVDTSKGIADVPEWFKGSRLNYAENLLRHKENDRVALYIAR 120
FW +FW +V + + + +G + + L H + +I
Sbjct: 27 FWDDFWFVLKVVLIIIRLKKYEK-----------RGELVTVLDKFLSHAKRQPRKPFIIY 75
Query: 121 EGKEEIVKVTFEELRQEVALFAAA-MRKMGVKKGDRVVGYLPNSEHAVEAMLAAASIGAI 179
EG T++++ + + A + +KKGD V + N V A +G +
Sbjct: 76 EGDI----YTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCV 131
Query: 180 WSSTSPDFGVNGVLDRFSQIQPKLIFSVEAVVYNGKEHNHMEKLQQVVKGLPDLKKVVVI 239
+ + + N +L+ P+ A+V +E++ LP L
Sbjct: 132 VAFLNTNIRSNSLLNCIRACGPR------ALVVGADLLGTVEEI------LPSLS----- 174
Query: 240 PYVSSRENIDL----SKIPNSVF-LDDFLATGTSEQAPQLEFEQLPFSHPLFIMFSSGTT 294
ENI + +P V L + L+T E P+ +F+SGTT
Sbjct: 175 ------ENISVWGMKDSVPQGVISLKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTSGTT 228
Query: 295 GAPKCMVHS 303
G PK V S
Sbjct: 229 GLPKAAVIS 237
>gi|13325055 solute carrier family 27 (fatty acid transporter),
member 6 [Homo sapiens]
Length = 619
Score = 33.9 bits (76), Expect = 0.50
Identities = 51/249 (20%), Positives = 89/249 (35%), Gaps = 44/249 (17%)
Query: 61 FWAEFWKFSGIVFSRVYDEVVDTSKGIADVPEWFKGSRLNYAENLLRHKENDRVALYIAR 120
FW +FW +V + + + +G + + L H + +I
Sbjct: 27 FWDDFWFVLKVVLIIIRLKKYEK-----------RGELVTVLDKFLSHAKRQPRKPFIIY 75
Query: 121 EGKEEIVKVTFEELRQEVALFAAA-MRKMGVKKGDRVVGYLPNSEHAVEAMLAAASIGAI 179
EG T++++ + + A + +KKGD V + N V A +G +
Sbjct: 76 EGDI----YTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCV 131
Query: 180 WSSTSPDFGVNGVLDRFSQIQPKLIFSVEAVVYNGKEHNHMEKLQQVVKGLPDLKKVVVI 239
+ + + N +L+ P+ A+V +E++ LP L
Sbjct: 132 VAFLNTNIRSNSLLNCIRACGPR------ALVVGADLLGTVEEI------LPSLS----- 174
Query: 240 PYVSSRENIDL----SKIPNSVF-LDDFLATGTSEQAPQLEFEQLPFSHPLFIMFSSGTT 294
ENI + +P V L + L+T E P+ +F+SGTT
Sbjct: 175 ------ENISVWGMKDSVPQGVISLKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTSGTT 228
Query: 295 GAPKCMVHS 303
G PK V S
Sbjct: 229 GLPKAAVIS 237
>gi|42544134 SA hypertension-associated homolog isoform 2 [Homo
sapiens]
Length = 438
Score = 32.3 bits (72), Expect = 1.5
Identities = 65/337 (19%), Positives = 124/337 (36%), Gaps = 46/337 (13%)
Query: 90 VPEWFKGSRLNYAENLLRH---------KENDRVALYIAREGKEEIVKVTFEELRQEVAL 140
+PE+F N+A+++L K ++ +I R G+E ++ +FEEL
Sbjct: 54 IPEYF-----NFAKDVLDQWTDKEKAGKKPSNPAFWWINRNGEE--MRWSFEELGSLSRK 106
Query: 141 FAAAMRKM-GVKKGDRVVGYLPNSEHAVEAMLAAASIGAIWSSTSPDFGVNGVLDRFSQI 199
FA + + +++GDRV+ LP A +A G + + +L R
Sbjct: 107 FANILSEACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSS 166
Query: 200 QPKLIFSVEAVVYNGKEHNHMEKLQQVVKGLPDLKKVVVIPYVSSRENIDLSKIPNSVFL 259
+ I + + + + V +L +++ +SRE K
Sbjct: 167 KANCIITNDVLA---------PAVDAVASKCENLHSKLIVSE-NSREGWGNLKELMKHAS 216
Query: 260 DDFLATGTSEQAPQLEFEQLPFSHPLFIMFSSGTTGAPKCMVHSAGGTLIQHLKEHLLHG 319
D T + + I F+SGT+G PK H+ +
Sbjct: 217 DSHTCVKTKH------------NEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGRFWL 264
Query: 320 NMTSSDILLCYTTVGW--MMWNWMVSLLATGAAMVLYDGSPLVPTPNVLWDLVDRIGITV 377
++T SD++ + GW W+ + S GA + + PT + + + ITV
Sbjct: 265 DLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACVFTHHLPRFEPTS--ILQTLSKYPITV 322
Query: 378 LVTGAKWLSVLEEKAMKPVETHSLQMLHTILSTGSPL 414
+ +V + ++ + L +S G P+
Sbjct: 323 FCSAP---TVYRMLVQNDITSYKFKSLKHCVSAGEPI 356
>gi|206597515 ArfGAP with RhoGAP domain, ankyrin repeat and PH
domain 1 isoform d [Homo sapiens]
Length = 1133
Score = 31.6 bits (70), Expect = 2.5
Identities = 21/76 (27%), Positives = 33/76 (43%)
Query: 343 SLLATGAAMVLYDGSPLVPTPNVLWDLVDRIGITVLVTGAKWLSVLEEKAMKPVETHSLQ 402
+LL GA + + G P PTP L + + + + V +MKP+E H
Sbjct: 374 ALLGCGAGINCFSGDPEAPTPLALAEQAGQTLQMEFLRNNRTTEVPRLDSMKPLEKHYSV 433
Query: 403 MLHTILSTGSPLKAQS 418
+L T+ +G K S
Sbjct: 434 VLPTVSHSGFLYKTAS 449
>gi|109948283 KIAA0020 protein [Homo sapiens]
Length = 648
Score = 31.6 bits (70), Expect = 2.5
Identities = 36/164 (21%), Positives = 70/164 (42%), Gaps = 16/164 (9%)
Query: 110 ENDRVALYIAREGKEEIVKVTFEELRQEVALFAAAMRKMGVKKGDRVVGYLPNSEHAVEA 169
++ RV + G EE K FEELR ++ + A + K + G P + +
Sbjct: 178 DSTRVIQCYIQYGNEEQRKQAFEELRDDLVELSKAKYSRNIVKKFLMYGSKPQIAEIIRS 237
Query: 170 -------MLAAASIGAIWSSTSPDFGVNGVLDRFSQIQPKLIFSVEAVVYNGKEHNHMEK 222
ML A AI D +L++ + + +L + +Y +H ++K
Sbjct: 238 FKGHVRKMLRHAEASAIVEYAYND---KAILEQRNMLTEEL-YGNTFQLYKSADHRTLDK 293
Query: 223 LQQV----VKGLPDLKKVVVIPYVSSRENIDLSKIPNSVFLDDF 262
+ +V ++ + D K ++ P ++ +E + + + VFLD F
Sbjct: 294 VLEVQPEKLELIMDEMKQILTP-MAQKEAVIKHSLVHKVFLDFF 336
>gi|18104962 amyloid beta precursor protein-binding protein 2 [Homo
sapiens]
Length = 585
Score = 31.6 bits (70), Expect = 2.5
Identities = 32/116 (27%), Positives = 47/116 (40%), Gaps = 21/116 (18%)
Query: 8 GREEILECQVMWEPDSKKNTQMDRFRAAVGAACGL--ALESYDDLYHWSVESYSDFWAEF 65
G E Q + SK Q ++ A G C L A YD+ Y W +E+ + A
Sbjct: 182 GEETFKLAQTYMDKLSKHGQQANK-AALYGELCALLFAKSHYDEAYKWCIEAMKEITA-- 238
Query: 66 WKFSGIVFSRVYDEVVDTSKGIADVPEWFKGSRLNYAENLLRHKENDRVALYIARE 121
G+ V D + SK E+ K AE L++H A+Y+AR+
Sbjct: 239 ----GLPVKVVVDVLRQASKACVVKREFKK------AEQLIKH------AVYLARD 278
>gi|145312259 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 31.6 bits (70), Expect = 2.5
Identities = 28/109 (25%), Positives = 55/109 (50%), Gaps = 16/109 (14%)
Query: 563 FEEVEDSLC--VPQYNKYREERVILFLKMASGHAFQPDLVKRIRDAIRMGLSARHVPSLI 620
F+ +E SL P +++ EE + F ++ ++P LV +I ++ G+S P +
Sbjct: 414 FQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKP-LVAKISSYVQTGISTW--PKIY 470
Query: 621 LETKGIPYTLNGKKVEVAVKQIIAGKAVEQGGAFSNPETLDLYRDIPEL 669
L T NGKK+++ ++ + G A+E PE ++ R +P++
Sbjct: 471 LYD-----TSNGKKLDIGLELVHKGYAIEL------PEDIEENRAVPDM 508
>gi|145312246 tudor and KH domain containing isoform b [Homo
sapiens]
Length = 516
Score = 31.6 bits (70), Expect = 2.5
Identities = 28/109 (25%), Positives = 55/109 (50%), Gaps = 16/109 (14%)
Query: 563 FEEVEDSLC--VPQYNKYREERVILFLKMASGHAFQPDLVKRIRDAIRMGLSARHVPSLI 620
F+ +E SL P +++ EE + F ++ ++P LV +I ++ G+S P +
Sbjct: 369 FQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKP-LVAKISSYVQTGISTW--PKIY 425
Query: 621 LETKGIPYTLNGKKVEVAVKQIIAGKAVEQGGAFSNPETLDLYRDIPEL 669
L T NGKK+++ ++ + G A+E PE ++ R +P++
Sbjct: 426 LYD-----TSNGKKLDIGLELVHKGYAIEL------PEDIEENRAVPDM 463
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,073,490
Number of Sequences: 37866
Number of extensions: 1171805
Number of successful extensions: 2446
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 2386
Number of HSP's gapped (non-prelim): 48
length of query: 672
length of database: 18,247,518
effective HSP length: 109
effective length of query: 563
effective length of database: 14,120,124
effective search space: 7949629812
effective search space used: 7949629812
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.