Search of human proteins with 31543983

Search of human proteins with 31543983

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31543983 ADP-ribosylation factor GTPase activating protein 2
[Homo sapiens]
         (521 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31543983 ADP-ribosylation factor GTPase activating protein 2 ...  1030   0.0  
gi|214829673 ADP-ribosylation factor GTPase activating protein 3...   525   e-149
gi|214829714 ADP-ribosylation factor GTPase activating protein 3...   439   e-123
gi|28416436 ADP-ribosylation factor GTPase activating protein 1 ...   107   3e-23
gi|8922652 ADP-ribosylation factor GTPase activating protein 1 i...   105   1e-22
gi|21264558 stromal membrane-associated GTPase-activating protei...    87   5e-17
gi|23943872 small ArfGAP2 [Homo sapiens]                               85   1e-16
gi|113204622 stromal membrane-associated GTPase-activating prote...    82   9e-16
gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH doma...    78   2e-14
gi|187608516 centaurin, beta 2 [Homo sapiens]                          78   2e-14
gi|110227613 centaurin, gamma 3 isoform a [Homo sapiens]               75   2e-13
gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]          73   6e-13
gi|7661962 centaurin, gamma 1 isoform PIKE-S [Homo sapiens]            73   6e-13
gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens]                72   2e-12
gi|80978930 centaurin, gamma 2 isoform 1 [Homo sapiens]                72   2e-12
gi|46094081 development and differentiation enhancing factor 1 [...    70   4e-12
gi|166851846 centaurin, gamma-like family, member 3 [Homo sapiens]     70   4e-12
gi|156104893 ArfGAP with GTPase domain, ankyrin repeat and PH do...    69   8e-12
gi|148806877 ankyrin repeat and GTPase domain Arf GTPase activat...    69   1e-11
gi|117956373 ArfGAP with GTPase domain, ankyrin repeat and PH do...    69   1e-11
gi|7661880 centaurin beta1 [Homo sapiens]                              68   2e-11
gi|239744074 PREDICTED: ArfGAP with GTPase domain, ankyrin repea...    67   3e-11
gi|239744064 PREDICTED: ArfGAP with GTPase domain, ankyrin repea...    67   3e-11
gi|117956371 ArfGAP with GTPase domain, ankyrin repeat and PH do...    67   3e-11
gi|6806913 centaurin, alpha 1 [Homo sapiens]                           67   4e-11
gi|221136914 ArfGAP with GTPase domain, ankyrin repeat and PH do...    64   3e-10
gi|221307473 ArfGAP with SH3 domain, ankyrin repeat and PH domai...    64   4e-10
gi|19923540 ArfGAP with SH3 domain, ankyrin repeat and PH domain...    64   4e-10
gi|206597522 ArfGAP with SH3 domain, ankyrin repeat and PH domai...    63   6e-10
gi|4502249 ArfGAP with SH3 domain, ankyrin repeat and PH domain ...    63   6e-10

>gi|31543983 ADP-ribosylation factor GTPase activating protein 2
           [Homo sapiens]
          Length = 521

 Score = 1030 bits (2664), Expect = 0.0
 Identities = 521/521 (100%), Positives = 521/521 (100%)

Query: 1   MAAEPNKTEIQTLFKRLRAVPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHL 60
           MAAEPNKTEIQTLFKRLRAVPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHL
Sbjct: 1   MAAEPNKTEIQTLFKRLRAVPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHL 60

Query: 61  SFIRSTELDSNWNWFQLRCMQVGGNANATAFFRQHGCTANDANTKYNSRAAQMYREKIRQ 120
           SFIRSTELDSNWNWFQLRCMQVGGNANATAFFRQHGCTANDANTKYNSRAAQMYREKIRQ
Sbjct: 61  SFIRSTELDSNWNWFQLRCMQVGGNANATAFFRQHGCTANDANTKYNSRAAQMYREKIRQ 120

Query: 121 LGSAALARHGTDLWIDNMSSAVPNHSPEKKDSDFFTEHTQPPAWDAPATEPSGTQQPAPS 180
           LGSAALARHGTDLWIDNMSSAVPNHSPEKKDSDFFTEHTQPPAWDAPATEPSGTQQPAPS
Sbjct: 121 LGSAALARHGTDLWIDNMSSAVPNHSPEKKDSDFFTEHTQPPAWDAPATEPSGTQQPAPS 180

Query: 181 TESSGLAQPEHGPNTDLLGTSPKASLELKSSIIGKKKPAAAKKGLGAKKGLGAQKVSSQS 240
           TESSGLAQPEHGPNTDLLGTSPKASLELKSSIIGKKKPAAAKKGLGAKKGLGAQKVSSQS
Sbjct: 181 TESSGLAQPEHGPNTDLLGTSPKASLELKSSIIGKKKPAAAKKGLGAKKGLGAQKVSSQS 240

Query: 241 FSEIERQAQVAEKLREQQAADAKKQAEESMVASMRLAYQELQIDRKKEEKKLQNLEGKKR 300
           FSEIERQAQVAEKLREQQAADAKKQAEESMVASMRLAYQELQIDRKKEEKKLQNLEGKKR
Sbjct: 241 FSEIERQAQVAEKLREQQAADAKKQAEESMVASMRLAYQELQIDRKKEEKKLQNLEGKKR 300

Query: 301 EQAERLGMGLVSRSSVSHSVLSEMQVIEQETPVSAKSSRSQLDLFDDVGTFASGPPKYKD 360
           EQAERLGMGLVSRSSVSHSVLSEMQVIEQETPVSAKSSRSQLDLFDDVGTFASGPPKYKD
Sbjct: 301 EQAERLGMGLVSRSSVSHSVLSEMQVIEQETPVSAKSSRSQLDLFDDVGTFASGPPKYKD 360

Query: 361 NPFSLGESFGSRWDTDAAWGMDRVEEKEPEVTISSIRPISERATNRREVESRSSGLESSE 420
           NPFSLGESFGSRWDTDAAWGMDRVEEKEPEVTISSIRPISERATNRREVESRSSGLESSE
Sbjct: 361 NPFSLGESFGSRWDTDAAWGMDRVEEKEPEVTISSIRPISERATNRREVESRSSGLESSE 420

Query: 421 ARQKFAGAKAISSDMFFGREVDAEYEARSRLQQLSGSSAISSSDLFGDMDGAHGAGSVSL 480
           ARQKFAGAKAISSDMFFGREVDAEYEARSRLQQLSGSSAISSSDLFGDMDGAHGAGSVSL
Sbjct: 421 ARQKFAGAKAISSDMFFGREVDAEYEARSRLQQLSGSSAISSSDLFGDMDGAHGAGSVSL 480

Query: 481 GNVLPTADIAQFKQGVKSVAGKMAVLANGVMNSLQDRYGSY 521
           GNVLPTADIAQFKQGVKSVAGKMAVLANGVMNSLQDRYGSY
Sbjct: 481 GNVLPTADIAQFKQGVKSVAGKMAVLANGVMNSLQDRYGSY 521


>gi|214829673 ADP-ribosylation factor GTPase activating protein 3
           isoform 1 [Homo sapiens]
          Length = 516

 Score =  525 bits (1351), Expect = e-149
 Identities = 289/529 (54%), Positives = 369/529 (69%), Gaps = 27/529 (5%)

Query: 4   EPNKTEIQTLFKRLRAVPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFI 63
           +P+K +I T+FKRLR+VPTNK CFDCGAKNPSWASITYGVFLCIDCSG HRSLGVHLSFI
Sbjct: 3   DPSKQDILTIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFI 62

Query: 64  RSTELDSNWNWFQLRCMQVGGNANATAFFRQHGCTANDANTKYNSRAAQMYREKIRQLGS 123
           RSTELDSNW+WFQLRCMQVGGNA+A++FF QHGC+ ND N KYNSRAAQ+YREKI+ L S
Sbjct: 63  RSTELDSNWSWFQLRCMQVGGNASASSFFHQHGCSTNDTNAKYNSRAAQLYREKIKSLAS 122

Query: 124 AALARHGTDLWIDNMSSAVPNHSPEKKDSDFFTEHTQP----PAWDAPATEPSG-TQQPA 178
            A  +HGTDLW+D  S  VP  SP  K+ DFF  H  P     AW +   EPS  T +P 
Sbjct: 123 QATRKHGTDLWLD--SCVVPPLSPPPKEEDFFASHVSPEVSDTAWASAIAEPSSLTSRPV 180

Query: 179 PSTESSGLAQPEHGPNTDLLGTSPKASLELKSSIIGKKKPAAAKKGLGAKKG-LGAQKVS 237
            +T  +     E GP+ + L    KA+LE+ S I  KKKP  AKKGLGAKKG LGAQK++
Sbjct: 181 ETTLENNEGGQEQGPSVEGLNVPTKATLEVSSII--KKKPNQAKKGLGAKKGSLGAQKLA 238

Query: 238 SQSFSEIERQAQVAEKLREQQAADAKKQAEESMVASMRLAYQELQIDRKKEEKKLQNLEG 297
           +  F+EIE+QAQ A+K++EQ+        EES+V+S+RLAY++L+I  KK+EK   N+ G
Sbjct: 239 NTCFNEIEKQAQAADKMKEQEDLAKVVSKEESIVSSLRLAYKDLEIQMKKDEK--MNISG 296

Query: 298 KKREQAERLGMGLVS-RSSVSHSVLSEMQVIEQETPVSAKSSRSQLDLFDDVGTFASGPP 356
           KK   ++RLGMG  + RS +SHSV S+MQ IEQE+P+ AK  +   D  DD  ++ +   
Sbjct: 297 KKNVDSDRLGMGFGNCRSVISHSVTSDMQTIEQESPIMAKPRKKYNDDSDD--SYFTSSS 354

Query: 357 KYKDNPFSLGESFGSRWD--TDAAWGMDRVEEKEP--EVTISSIRPISERATNRREVESR 412
            Y D P  L  S  S WD  +D+ W  +  ++ E   + T  S RP + R  +   VE+ 
Sbjct: 355 SYFDEPVELRSSSFSSWDDSSDSYWKKETSKDTETVLKTTGYSDRPTARRKPDYEPVEN- 413

Query: 413 SSGLESSEARQKFAGAKAISSDMFFGREVDAEYEARSRLQQLSGSSAISSSDLFGDMDGA 472
                + EA++KF   KAISSDM+FGR+  A+YE R+RL++LS SS+ISS+DLF +    
Sbjct: 414 -----TDEAQKKFGNVKAISSDMYFGRQSQADYETRARLERLSASSSISSADLF-EEPRK 467

Query: 473 HGAGSVSLGNVLPTA-DIAQFKQGVKSVAGKMAVLANGVMNSLQDRYGS 520
             AG+ SL +VLP A D+AQFKQGV+SVAGK++V ANGV+ S+QDRYGS
Sbjct: 468 QPAGNYSLSSVLPNAPDMAQFKQGVRSVAGKLSVFANGVVTSIQDRYGS 516


>gi|214829714 ADP-ribosylation factor GTPase activating protein 3
           isoform 2 [Homo sapiens]
          Length = 472

 Score =  439 bits (1129), Expect = e-123
 Identities = 260/529 (49%), Positives = 334/529 (63%), Gaps = 71/529 (13%)

Query: 4   EPNKTEIQTLFKRLRAVPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFI 63
           +P+K +I T+FKRLR+VPTNK CFDCGAKNPSWASITYGVFLCIDCSG HRSLGVHLSFI
Sbjct: 3   DPSKQDILTIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFI 62

Query: 64  RSTELDSNWNWFQLRCMQVGGNANATAFFRQHGCTANDANTKYNSRAAQMYREKIRQLGS 123
           RSTELDSNW+WFQLRCMQVGGNA+A                                   
Sbjct: 63  RSTELDSNWSWFQLRCMQVGGNASA----------------------------------- 87

Query: 124 AALARHGTDLWIDNMSSAVPNHSPEKKDSDFFTEHTQPP----AWDAPATEPSG-TQQPA 178
                    LW+D  S  VP  SP  K+ DFF  H  P     AW +   EPS  T +P 
Sbjct: 88  ---------LWLD--SCVVPPLSPPPKEEDFFASHVSPEVSDTAWASAIAEPSSLTSRPV 136

Query: 179 PSTESSGLAQPEHGPNTDLLGTSPKASLELKSSIIGKKKPAAAKKGLGAKKG-LGAQKVS 237
            +T  +     E GP+ + L    KA+LE+ S I  KKKP  AKKGLGAKKG LGAQK++
Sbjct: 137 ETTLENNEGGQEQGPSVEGLNVPTKATLEVSSII--KKKPNQAKKGLGAKKGSLGAQKLA 194

Query: 238 SQSFSEIERQAQVAEKLREQQAADAKKQAEESMVASMRLAYQELQIDRKKEEKKLQNLEG 297
           +  F+EIE+QAQ A+K++EQ+        EES+V+S+RLAY++L+I  KK+EK   N+ G
Sbjct: 195 NTCFNEIEKQAQAADKMKEQEDLAKVVSKEESIVSSLRLAYKDLEIQMKKDEK--MNISG 252

Query: 298 KKREQAERLGMGLVS-RSSVSHSVLSEMQVIEQETPVSAKSSRSQLDLFDDVGTFASGPP 356
           KK   ++RLGMG  + RS +SHSV S+MQ IEQE+P+ AK  +   D  DD  ++ +   
Sbjct: 253 KKNVDSDRLGMGFGNCRSVISHSVTSDMQTIEQESPIMAKPRKKYNDDSDD--SYFTSSS 310

Query: 357 KYKDNPFSLGESFGSRWD--TDAAWGMDRVEEKEP--EVTISSIRPISERATNRREVESR 412
            Y D P  L  S  S WD  +D+ W  +  ++ E   + T  S RP + R  +   VE+ 
Sbjct: 311 SYFDEPVELRSSSFSSWDDSSDSYWKKETSKDTETVLKTTGYSDRPTARRKPDYEPVEN- 369

Query: 413 SSGLESSEARQKFAGAKAISSDMFFGREVDAEYEARSRLQQLSGSSAISSSDLFGDMDGA 472
                + EA++KF   KAISSDM+FGR+  A+YE R+RL++LS SS+ISS+DLF +    
Sbjct: 370 -----TDEAQKKFGNVKAISSDMYFGRQSQADYETRARLERLSASSSISSADLF-EEPRK 423

Query: 473 HGAGSVSLGNVLPTA-DIAQFKQGVKSVAGKMAVLANGVMNSLQDRYGS 520
             AG+ SL +VLP A D+AQFKQGV+SVAGK++V ANGV+ S+QDRYGS
Sbjct: 424 QPAGNYSLSSVLPNAPDMAQFKQGVRSVAGKLSVFANGVVTSIQDRYGS 472


>gi|28416436 ADP-ribosylation factor GTPase activating protein 1
           isoform b [Homo sapiens]
          Length = 414

 Score =  107 bits (266), Expect = 3e-23
 Identities = 80/266 (30%), Positives = 120/266 (45%), Gaps = 13/266 (4%)

Query: 13  LFKRLRAVPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDSNW 72
           + K +R    N  CF+CGA NP W S+TYG+++C++CSG HR LGVHLSF+RS  +D  W
Sbjct: 9   VLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMD-KW 67

Query: 73  NWFQLRCMQVGGNANATAFF--RQHGCTANDANTKYNSRAAQMYREKIRQLGSA---ALA 127
              +L  M+ GGNA    F   ++          KYNSRAA ++R+K+  L      +L 
Sbjct: 68  KDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAEGREWSLE 127

Query: 128 RHGTDLWIDNMSSAVPNHSPEKKDSDFFTEHTQPPAWDAPATEPSGTQQPAPSTESSGLA 187
                 W       +P+              +   A++    +  G+ Q A      G  
Sbjct: 128 SSPAQNWTPPQPRTLPSMVHRVSGQPQSVTASSDKAFEDWLNDDLGSYQGAQGNRYVGFG 187

Query: 188 Q--PEHGPNTDLLGTSPKASLELKSSI-IGKKKPAAAKKGLGAKKGLGAQKVSSQSFSEI 244
              P      D L  +  +     SS   G  + A+A K  GA K  G+Q  +SQ F   
Sbjct: 188 NTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKE-GATK-FGSQ--ASQKFWGH 243

Query: 245 ERQAQVAEKLREQQAADAKKQAEESM 270
           ++Q + A +L      +  K A+E +
Sbjct: 244 KQQPEPASELGHSLNENVLKPAQEKV 269


>gi|8922652 ADP-ribosylation factor GTPase activating protein 1
           isoform a [Homo sapiens]
          Length = 406

 Score =  105 bits (262), Expect = 1e-22
 Identities = 76/259 (29%), Positives = 113/259 (43%), Gaps = 11/259 (4%)

Query: 13  LFKRLRAVPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDSNW 72
           + K +R    N  CF+CGA NP W S+TYG+++C++CSG HR LGVHLSF+RS  +D  W
Sbjct: 9   VLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMD-KW 67

Query: 73  NWFQLRCMQVGGNANATAFF--RQHGCTANDANTKYNSRAAQMYREKIRQLGSA---ALA 127
              +L  M+ GGNA    F   ++          KYNSRAA ++R+K+  L      +L 
Sbjct: 68  KDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAEGREWSLE 127

Query: 128 RHGTDLWIDNMSSAVPNHSPEKKDSDFFTEHTQPPAWDAPATEPSGTQQPAPSTESSGLA 187
                 W       +P+              +   A++    +  G+ Q A      G  
Sbjct: 128 SSPAQNWTPPQPRTLPSMVHRVSGQPQSVTASSDKAFEDWLNDDLGSYQGAQGNRYVGFG 187

Query: 188 Q--PEHGPNTDLLGTSPKASLELKSSII--GKKKPAAAKKGLGAKKGLGAQKVSSQSFSE 243
              P      D L  +  +     SS      +  +AAK+G        +QK S    S 
Sbjct: 188 NTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFGSQASQKASELGHSL 247

Query: 244 IERQAQVA-EKLREQQAAD 261
            E   + A EK++E +  D
Sbjct: 248 NENVLKPAQEKVKEGKIFD 266


>gi|21264558 stromal membrane-associated GTPase-activating protein 1
           isoform B [Homo sapiens]
          Length = 440

 Score = 86.7 bits (213), Expect = 5e-17
 Identities = 78/281 (27%), Positives = 118/281 (41%), Gaps = 34/281 (12%)

Query: 11  QTLFKRLRAVPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDS 70
           Q +  +L     NK C DC AK P WAS   GVF+CI C+G+HR+LGVH+S ++S  LD 
Sbjct: 18  QLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLD- 76

Query: 71  NWNWFQLRCMQVGGNANATAFFRQHGCTANDANTKYNSRAAQMYREKIRQLGSAALARHG 130
            W   Q++CMQ  GN  A   +        +AN   N R  Q      + +      ++ 
Sbjct: 77  QWTAEQIQCMQDMGNTKARLLY--------EANLPENFRRPQ----TDQAVEFFIRDKYE 124

Query: 131 TDLWIDNMSSAVPNHSPEKKDSDFFTE-HTQPPAWDAPA---------TEPSGTQQP--- 177
              + D  + A+ N   EKK  +   E   + PA    A          EP  +  P   
Sbjct: 125 KKKYYDKNAIAITNKEKEKKKEEKKREKEPEKPAKPLTAEKLQKKDQQLEPKKSTSPKKA 184

Query: 178 -APSTESSGLAQPEHGPNTDLLGTSPKAS--LELKSSIIGKKKPAAA-KKGLGAKKGLGA 233
             P+ +  GL  P   P T+   T P  +  L++   +I    PA       G      A
Sbjct: 185 AEPTVDLLGLDGPAVAPVTNGNTTVPPLNDDLDIFGPMISNPLPATVMPPAQGTPSAPAA 244

Query: 234 QKVSSQSFSEIERQAQVAEKLREQQAADAKKQAEESMVASM 274
             +S+ +  +++   +   K  E     AKKQ  +  + S+
Sbjct: 245 ATLSTVTSGDLDLFTEQTTKSEEV----AKKQLSKDSILSL 281


>gi|23943872 small ArfGAP2 [Homo sapiens]
          Length = 429

 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 64/232 (27%), Positives = 93/232 (40%), Gaps = 23/232 (9%)

Query: 11  QTLFKRLRAVPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDS 70
           Q +   L     NK C DC +K P WAS   GVF+CI C+G+HR+LGVH+S ++S  LD 
Sbjct: 13  QAVLANLLLEEDNKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLD- 71

Query: 71  NWNWFQLRCMQVGGNANATAFFRQHGCTANDANTKYNSRAAQMYREKI-------RQLGS 123
            W   Q++CMQ  GN  A   +  +         + +       R+K        R L  
Sbjct: 72  QWTQEQIQCMQEMGNGKANRLYEAY-LPETFRRPQIDPAVEGFIRDKYEKKKYMDRSLDI 130

Query: 124 AALARHGTDLWIDNMSSAVPNHS-----------PEKKDSDFFTEHTQPPAWDAPATEPS 172
            A  +   D W    S  VP              P+KK+       + P +  AP  +  
Sbjct: 131 NAFRKEKDDKW-KRGSEPVPEKKLEPVVFEKVKMPQKKEDPQLPRKSSPKS-TAPVMDLL 188

Query: 173 GTQQPAPSTESSGLAQPEHGPNTDLLGTSPKASLELKSSIIGKKKPAAAKKG 224
           G   P   + ++         + DLL + P  S      ++G   P A   G
Sbjct: 189 GLDAPVACSIANSKTSNTLEKDLDLLASVPSPSSSGSRKVVG-SMPTAGSAG 239


>gi|113204622 stromal membrane-associated GTPase-activating protein
           1 isoform A [Homo sapiens]
          Length = 467

 Score = 82.4 bits (202), Expect = 9e-16
 Identities = 43/102 (42%), Positives = 56/102 (54%), Gaps = 9/102 (8%)

Query: 11  QTLFKRLRAVPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDS 70
           Q +  +L     NK C DC AK P WAS   GVF+CI C+G+HR+LGVH+S ++S  LD 
Sbjct: 18  QLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLD- 76

Query: 71  NWNWFQLRCMQVGGNANATAFFRQHGCTANDANTKYNSRAAQ 112
            W   Q++CMQ  GN  A   +        +AN   N R  Q
Sbjct: 77  QWTAEQIQCMQDMGNTKARLLY--------EANLPENFRRPQ 110


>gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH domains
           3 [Homo sapiens]
          Length = 834

 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 38/76 (50%), Positives = 51/76 (67%), Gaps = 1/76 (1%)

Query: 11  QTLFKRLRAVPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDS 70
           +++ +R+++V  N  C DCG  +P WASI  GV LCI+CSG+HRSLGVH S +RS  LDS
Sbjct: 403 ESVLQRVQSVAGNSQCGDCGQPDPRWASINLGVLLCIECSGIHRSLGVHCSKVRSLTLDS 462

Query: 71  NWNWFQLRCMQVGGNA 86
            W    L+ M   GN+
Sbjct: 463 -WEPELLKLMCELGNS 477


>gi|187608516 centaurin, beta 2 [Homo sapiens]
          Length = 778

 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 36/75 (48%), Positives = 50/75 (66%), Gaps = 1/75 (1%)

Query: 11  QTLFKRLRAVPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDS 70
           ++  +R++ +P N +C DCG  +P WASI  G+ LCI+CSG+HRSLGVH S +RS  LD+
Sbjct: 399 ESALQRVQCIPGNASCCDCGLADPRWASINLGITLCIECSGIHRSLGVHFSKVRSLTLDT 458

Query: 71  NWNWFQLRCMQVGGN 85
            W    L+ M   GN
Sbjct: 459 -WEPELLKLMCELGN 472


>gi|110227613 centaurin, gamma 3 isoform a [Homo sapiens]
          Length = 911

 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 36/74 (48%), Positives = 45/74 (60%), Gaps = 1/74 (1%)

Query: 17  LRAVPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDSNWNWFQ 76
           +R V  N  C DC A NP WAS+  G  +CI+CSG+HR LG HLS +RS +LD +W    
Sbjct: 668 VRTVRGNSFCIDCDAPNPDWASLNLGALMCIECSGIHRHLGAHLSRVRSLDLD-DWPPEL 726

Query: 77  LRCMQVGGNANATA 90
           L  M   GNA A +
Sbjct: 727 LAVMTAMGNALANS 740


>gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]
          Length = 1192

 Score = 73.2 bits (178), Expect = 6e-13
 Identities = 29/53 (54%), Positives = 38/53 (71%)

Query: 17  LRAVPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELD 69
           +R    N  C DCGA NP+WAS+  G  +CI+CSG+HR+LG HLS +RS +LD
Sbjct: 937 IRNAKGNSICVDCGAPNPTWASLNLGALICIECSGIHRNLGTHLSRVRSLDLD 989


>gi|7661962 centaurin, gamma 1 isoform PIKE-S [Homo sapiens]
          Length = 836

 Score = 73.2 bits (178), Expect = 6e-13
 Identities = 29/53 (54%), Positives = 38/53 (71%)

Query: 17  LRAVPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELD 69
           +R    N  C DCGA NP+WAS+  G  +CI+CSG+HR+LG HLS +RS +LD
Sbjct: 581 IRNAKGNSICVDCGAPNPTWASLNLGALICIECSGIHRNLGTHLSRVRSLDLD 633


>gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens]
          Length = 804

 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 32/78 (41%), Positives = 49/78 (62%), Gaps = 1/78 (1%)

Query: 17  LRAVPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDSNWNWFQ 76
           +R +  N  C DC  +NP+WAS+  G  +CI+CSG+HR+LG HLS +RS +LD +W    
Sbjct: 562 IRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLD-DWPVEL 620

Query: 77  LRCMQVGGNANATAFFRQ 94
           ++ M   GN  A + + +
Sbjct: 621 IKVMSSIGNELANSVWEE 638


>gi|80978930 centaurin, gamma 2 isoform 1 [Homo sapiens]
          Length = 857

 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 32/78 (41%), Positives = 49/78 (62%), Gaps = 1/78 (1%)

Query: 17  LRAVPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDSNWNWFQ 76
           +R +  N  C DC  +NP+WAS+  G  +CI+CSG+HR+LG HLS +RS +LD +W    
Sbjct: 615 IRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLD-DWPVEL 673

Query: 77  LRCMQVGGNANATAFFRQ 94
           ++ M   GN  A + + +
Sbjct: 674 IKVMSSIGNELANSVWEE 691


>gi|46094081 development and differentiation enhancing factor 1
           [Homo sapiens]
          Length = 1129

 Score = 70.5 bits (171), Expect = 4e-12
 Identities = 30/76 (39%), Positives = 45/76 (59%)

Query: 11  QTLFKRLRAVPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDS 70
           + + + ++ +P N  C DCG+  P+W S   G+  CI+CSG+HR +GVH+S I+S ELD 
Sbjct: 439 KAIIEDVQRLPGNDICCDCGSSEPTWLSTNLGILTCIECSGIHREMGVHISRIQSLELDK 498

Query: 71  NWNWFQLRCMQVGGNA 86
                 L    VG N+
Sbjct: 499 LGTSELLLAKNVGNNS 514


>gi|166851846 centaurin, gamma-like family, member 3 [Homo sapiens]
          Length = 686

 Score = 70.5 bits (171), Expect = 4e-12
 Identities = 29/47 (61%), Positives = 35/47 (74%)

Query: 23  NKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELD 69
           N  C DC  +NP WAS+  GV +CI+CSG+HRSLG HLS +RS ELD
Sbjct: 476 NAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGPHLSRVRSLELD 522


>gi|156104893 ArfGAP with GTPase domain, ankyrin repeat and PH
           domain 4 [Homo sapiens]
          Length = 663

 Score = 69.3 bits (168), Expect = 8e-12
 Identities = 36/95 (37%), Positives = 54/95 (56%), Gaps = 5/95 (5%)

Query: 23  NKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDSNWNWFQLRCMQV 82
           N  C DC  +NP WAS+  GV +CI+CSG+HRSLG  LS +RS ELD +W     + M  
Sbjct: 453 NAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELD-DWPVELRKVMSS 511

Query: 83  GGNANATAFFRQHGCTANDANTKYNSRAAQMYREK 117
            GN  A + +      ++   TK + ++ +  +E+
Sbjct: 512 IGNDLANSIWE----GSSQGQTKPSEKSTREEKER 542


>gi|148806877 ankyrin repeat and GTPase domain Arf GTPase activating
           protein 11 [Homo sapiens]
          Length = 550

 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 33/70 (47%), Positives = 43/70 (61%), Gaps = 1/70 (1%)

Query: 23  NKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDSNWNWFQLRCMQV 82
           N  C DC  +NP WAS+  GV +CI+CSG+HRSLG  LS +RS ELD +W     + M  
Sbjct: 340 NSHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELD-DWPVELRKVMSS 398

Query: 83  GGNANATAFF 92
            GN  A + +
Sbjct: 399 IGNDLANSIW 408


>gi|117956373 ArfGAP with GTPase domain, ankyrin repeat and PH
           domain 7 [Homo sapiens]
          Length = 663

 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 36/95 (37%), Positives = 53/95 (55%), Gaps = 5/95 (5%)

Query: 23  NKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDSNWNWFQLRCMQV 82
           N  C DC  +NP WAS+  GV +CI+CSG+HRSLG  LS +RS ELD +W     + M  
Sbjct: 453 NAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELD-DWPVELRKVMSS 511

Query: 83  GGNANATAFFRQHGCTANDANTKYNSRAAQMYREK 117
            GN  A + +      ++   TK   ++ +  +E+
Sbjct: 512 IGNDLANSIWE----GSSQGRTKPTEKSTREEKER 542


>gi|7661880 centaurin beta1 [Homo sapiens]
          Length = 740

 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 31/55 (56%), Positives = 37/55 (67%)

Query: 16  RLRAVPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDS 70
           ++++V  N  C DC    P WASI  GV LCI CSG+HRSLGVH S +RS  LDS
Sbjct: 410 QVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDS 464


>gi|239744074 PREDICTED: ArfGAP with GTPase domain, ankyrin repeat
           and PH domain 9 [Homo sapiens]
          Length = 684

 Score = 67.4 bits (163), Expect = 3e-11
 Identities = 32/70 (45%), Positives = 42/70 (60%), Gaps = 1/70 (1%)

Query: 23  NKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDSNWNWFQLRCMQV 82
           N  C DC  +NP WAS+  GV +CI+CSG+HRS G  LS +RS ELD +W     + M  
Sbjct: 476 NAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELD-DWPVELRKVMSS 534

Query: 83  GGNANATAFF 92
            GN  A + +
Sbjct: 535 IGNELANSIW 544


>gi|239744064 PREDICTED: ArfGAP with GTPase domain, ankyrin repeat
           and PH domain 10 [Homo sapiens]
          Length = 684

 Score = 67.4 bits (163), Expect = 3e-11
 Identities = 32/70 (45%), Positives = 42/70 (60%), Gaps = 1/70 (1%)

Query: 23  NKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDSNWNWFQLRCMQV 82
           N  C DC  +NP WAS+  GV +CI+CSG+HRS G  LS +RS ELD +W     + M  
Sbjct: 476 NAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELD-DWPVELRKVMSS 534

Query: 83  GGNANATAFF 92
            GN  A + +
Sbjct: 535 IGNELANSIW 544


>gi|117956371 ArfGAP with GTPase domain, ankyrin repeat and PH
           domain 8 [Homo sapiens]
          Length = 663

 Score = 67.4 bits (163), Expect = 3e-11
 Identities = 35/95 (36%), Positives = 53/95 (55%), Gaps = 5/95 (5%)

Query: 23  NKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDSNWNWFQLRCMQV 82
           N  C DC  +NP WAS+  GV +CI+CSG+H SLG  LS +RS ELD +W     + M  
Sbjct: 453 NAHCVDCETQNPKWASLNLGVLMCIECSGIHHSLGTRLSRVRSLELD-DWPVELRKVMSS 511

Query: 83  GGNANATAFFRQHGCTANDANTKYNSRAAQMYREK 117
            GN  A + +      ++   TK + ++ +  +E+
Sbjct: 512 IGNDLANSIWE----GSSQGQTKPSEKSTREEKER 542


>gi|6806913 centaurin, alpha 1 [Homo sapiens]
          Length = 374

 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 37/92 (40%), Positives = 52/92 (56%), Gaps = 7/92 (7%)

Query: 1  MAAEPNKTEIQTLFKRLRAVPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHL 60
          MA E  +  ++ L +     P N  C DCGA +P WAS T GVF+C+ CSG+HR++   +
Sbjct: 1  MAKERRRAVLELLQR-----PGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQV 54

Query: 61 SFIRSTELDSNWNWFQLRCMQVGGNANATAFF 92
          S ++S  LD+ W   Q+  M   GN  A A F
Sbjct: 55 SKVKSVRLDA-WEEAQVEFMASHGNDAARARF 85


>gi|221136914 ArfGAP with GTPase domain, ankyrin repeat and PH
           domain 5 [Homo sapiens]
          Length = 686

 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 32/70 (45%), Positives = 42/70 (60%), Gaps = 1/70 (1%)

Query: 23  NKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDSNWNWFQLRCMQV 82
           N  C D   +NP WAS+  GV +CI+CSG+HRSLG  LS +RS ELD +W     + M  
Sbjct: 476 NAHCVDYETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELD-DWPVELRKVMSS 534

Query: 83  GGNANATAFF 92
            GN  A + +
Sbjct: 535 IGNDLANSIW 544


>gi|221307473 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
           isoform b [Homo sapiens]
          Length = 894

 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 28/57 (49%), Positives = 35/57 (61%)

Query: 13  LFKRLRAVPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELD 69
           L   +++ P N  C DCGA +P+W S   GV  CI CSGVHR LGV  S ++S  LD
Sbjct: 419 LIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLD 475


>gi|19923540 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
           isoform a [Homo sapiens]
          Length = 903

 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 28/57 (49%), Positives = 35/57 (61%)

Query: 13  LFKRLRAVPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELD 69
           L   +++ P N  C DCGA +P+W S   GV  CI CSGVHR LGV  S ++S  LD
Sbjct: 428 LIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLD 484


>gi|206597522 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
           isoform b [Homo sapiens]
          Length = 961

 Score = 63.2 bits (152), Expect = 6e-10
 Identities = 25/57 (43%), Positives = 36/57 (63%)

Query: 13  LFKRLRAVPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELD 69
           +   ++ +  N  C DCGA +P+W S   G+  CI+CSG+HR LGVH S ++S  LD
Sbjct: 423 IISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLTLD 479


>gi|4502249 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
           isoform a [Homo sapiens]
          Length = 1006

 Score = 63.2 bits (152), Expect = 6e-10
 Identities = 25/57 (43%), Positives = 36/57 (63%)

Query: 13  LFKRLRAVPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELD 69
           +   ++ +  N  C DCGA +P+W S   G+  CI+CSG+HR LGVH S ++S  LD
Sbjct: 423 IISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLTLD 479


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.125    0.355 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,856,678
Number of Sequences: 37866
Number of extensions: 875733
Number of successful extensions: 5560
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 108
Number of HSP's successfully gapped in prelim test: 328
Number of HSP's that attempted gapping in prelim test: 4475
Number of HSP's gapped (non-prelim): 1265
length of query: 521
length of database: 18,247,518
effective HSP length: 107
effective length of query: 414
effective length of database: 14,195,856
effective search space: 5877084384
effective search space used: 5877084384
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.