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Search of human proteins with 31543091
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31543091 MAK16 homolog [Homo sapiens]
(300 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31543091 MAK16 homolog [Homo sapiens] 603 e-173
gi|224465235 euchromatic histone-lysine N-methyltransferase 1 is... 54 2e-07
gi|224465233 euchromatic histone-lysine N-methyltransferase 1 is... 54 2e-07
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 54 2e-07
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 51 1e-06
gi|55956788 nucleolin [Homo sapiens] 50 2e-06
gi|4503257 death-domain associated protein isoform a [Homo sapiens] 50 3e-06
gi|215422388 death-domain associated protein isoform a [Homo sap... 50 3e-06
gi|215422366 death-domain associated protein isoform b [Homo sap... 50 3e-06
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 49 5e-06
gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear... 47 2e-05
gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear... 47 2e-05
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 47 2e-05
gi|55741677 SET domain containing 1A [Homo sapiens] 47 2e-05
gi|106507301 DNA-directed DNA polymerase alpha 1 [Homo sapiens] 47 2e-05
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens] 47 3e-05
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] 46 3e-05
gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens] 46 3e-05
gi|42740903 MTERF domain containing 2 [Homo sapiens] 46 5e-05
gi|115529449 upstream binding transcription factor, RNA polymera... 46 5e-05
gi|115529451 upstream binding transcription factor, RNA polymera... 46 5e-05
gi|7657671 upstream binding transcription factor, RNA polymerase... 46 5e-05
gi|95147555 microtubule-associated protein 1A [Homo sapiens] 45 6e-05
gi|221219020 NYD-SP11 protein [Homo sapiens] 45 8e-05
gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 45 8e-05
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 45 8e-05
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens] 45 1e-04
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens] 45 1e-04
gi|115529475 polymerase (RNA) III (DNA directed) polypeptide G (... 45 1e-04
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 44 1e-04
>gi|31543091 MAK16 homolog [Homo sapiens]
Length = 300
Score = 603 bits (1555), Expect = e-173
Identities = 300/300 (100%), Positives = 300/300 (100%)
Query: 1 MQSDDVIWDTLGNKQFCSFKIRTKTQSFCRNEYSLTGLCNRSSCPLANSQYATIKEEKGQ 60
MQSDDVIWDTLGNKQFCSFKIRTKTQSFCRNEYSLTGLCNRSSCPLANSQYATIKEEKGQ
Sbjct: 1 MQSDDVIWDTLGNKQFCSFKIRTKTQSFCRNEYSLTGLCNRSSCPLANSQYATIKEEKGQ 60
Query: 61 CYLYMKVIERAAFPRRLWERVRLSKNYEKALEQIDENLIYWPRFIRHKCKQRFTKITQYL 120
CYLYMKVIERAAFPRRLWERVRLSKNYEKALEQIDENLIYWPRFIRHKCKQRFTKITQYL
Sbjct: 61 CYLYMKVIERAAFPRRLWERVRLSKNYEKALEQIDENLIYWPRFIRHKCKQRFTKITQYL 120
Query: 121 IRIRKLTLKRQRKLVPLSKKVERREKRREEKALIAAQLDNAIEKELLERLKQDTYGDIYN 180
IRIRKLTLKRQRKLVPLSKKVERREKRREEKALIAAQLDNAIEKELLERLKQDTYGDIYN
Sbjct: 121 IRIRKLTLKRQRKLVPLSKKVERREKRREEKALIAAQLDNAIEKELLERLKQDTYGDIYN 180
Query: 181 FPIHAFDKALEQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKL 240
FPIHAFDKALEQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKL
Sbjct: 181 FPIHAFDKALEQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKL 240
Query: 241 DASSDEDQDGKSSSEEEEEKALSAKHKGKMPLRGPLQRKRAYVEIEYEQETEPVAKAKTT 300
DASSDEDQDGKSSSEEEEEKALSAKHKGKMPLRGPLQRKRAYVEIEYEQETEPVAKAKTT
Sbjct: 241 DASSDEDQDGKSSSEEEEEKALSAKHKGKMPLRGPLQRKRAYVEIEYEQETEPVAKAKTT 300
>gi|224465235 euchromatic histone-lysine N-methyltransferase 1
isoform 2 [Homo sapiens]
Length = 808
Score = 53.5 bits (127), Expect = 2e-07
Identities = 54/228 (23%), Positives = 101/228 (44%), Gaps = 34/228 (14%)
Query: 81 VRLSKNYEKALEQIDENLIYWPRFIRHKCKQRFTKITQYLIRIR--KLTLKRQRKLVP-- 136
VR ++++++ E+I++N+ F R + F + Q L + + T K Q +P
Sbjct: 224 VREARDHKEPKEEINKNI---SDFGRQQLLPPFPSLHQSLPQNQCYMATTKSQTACLPFV 280
Query: 137 LSKKVERREKRREEKALIAAQLDNAIEKE--LLERLKQDTYG--------DIYNFPIHAF 186
L+ V R++KRR + + + K+ ++E K T+ D+ +H
Sbjct: 281 LAAAVSRKKKRRMGTYSLVPKKKTKVLKQRTVIEMFKSITHSTVGSKGEKDLGASSLHVN 340
Query: 187 DKALEQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASSDE 246
++LE +SD D+EE ++DD + ED + +S+ + K+D S+E
Sbjct: 341 GESLEM---DSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSKESMSEADRAQKMDGESEE 397
Query: 247 DQDGKSSSEEEE--------------EKALSAKHKGKMPLRGPLQRKR 280
+Q+ + EEEE +K L K K P P +++R
Sbjct: 398 EQESVDTGEEEEGGDESDLSSESSIKKKFLKRKGKTDSPWIKPARKRR 445
>gi|224465233 euchromatic histone-lysine N-methyltransferase 1
isoform 1 [Homo sapiens]
Length = 1298
Score = 53.5 bits (127), Expect = 2e-07
Identities = 54/228 (23%), Positives = 101/228 (44%), Gaps = 34/228 (14%)
Query: 81 VRLSKNYEKALEQIDENLIYWPRFIRHKCKQRFTKITQYLIRIR--KLTLKRQRKLVP-- 136
VR ++++++ E+I++N+ F R + F + Q L + + T K Q +P
Sbjct: 224 VREARDHKEPKEEINKNI---SDFGRQQLLPPFPSLHQSLPQNQCYMATTKSQTACLPFV 280
Query: 137 LSKKVERREKRREEKALIAAQLDNAIEKE--LLERLKQDTYG--------DIYNFPIHAF 186
L+ V R++KRR + + + K+ ++E K T+ D+ +H
Sbjct: 281 LAAAVSRKKKRRMGTYSLVPKKKTKVLKQRTVIEMFKSITHSTVGSKGEKDLGASSLHVN 340
Query: 187 DKALEQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASSDE 246
++LE +SD D+EE ++DD + ED + +S+ + K+D S+E
Sbjct: 341 GESLEM---DSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSKESMSEADRAQKMDGESEE 397
Query: 247 DQDGKSSSEEEE--------------EKALSAKHKGKMPLRGPLQRKR 280
+Q+ + EEEE +K L K K P P +++R
Sbjct: 398 EQESVDTGEEEEGGDESDLSSESSIKKKFLKRKGKTDSPWIKPARKRR 445
>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member B [Homo sapiens]
Length = 251
Score = 53.5 bits (127), Expect = 2e-07
Identities = 38/98 (38%), Positives = 49/98 (50%), Gaps = 11/98 (11%)
Query: 160 NAIEKELLERLKQDTYGDIYNFPIHAFDKALEQQEAESDSSDTEEKDDDDDDEEDVGKRE 219
N + + + L Q TY D Y+ D+ +AE D D EE+D++ +DEED E
Sbjct: 129 NDYRESVFKLLPQLTYLDGYDRE----DQEAPDSDAEVDGVDEEEEDEEGEDEED----E 180
Query: 220 FVEDGEVDESDISDFEDMDKLDASSDEDQDGKSSSEEE 257
EDGE +E D D ED D DED D S EEE
Sbjct: 181 DDEDGEEEEFDEEDDEDED---VEGDEDDDEVSEEEEE 215
Score = 45.4 bits (106), Expect = 6e-05
Identities = 30/82 (36%), Positives = 45/82 (54%), Gaps = 12/82 (14%)
Query: 187 DKALEQQEAESDSSDTEEK-DDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASSD 245
D+ E +E E D EE+ D++DD++EDV +G+ D+ ++S+ E+ LD D
Sbjct: 171 DEEGEDEEDEDDEDGEEEEFDEEDDEDEDV-------EGDEDDDEVSEEEEEFGLD-EED 222
Query: 246 EDQDGKSSSEEEEEKALSAKHK 267
ED+D EEEEE K K
Sbjct: 223 EDED---EDEEEEEGGKGEKRK 241
Score = 35.0 bits (79), Expect = 0.081
Identities = 29/127 (22%), Positives = 57/127 (44%), Gaps = 12/127 (9%)
Query: 133 KLVPLSKKVERREKRREEKALIAAQLDNAIEKELLERLKQDTYGDIYNFPIHAFDKALEQ 192
KL+P ++ ++ +E A++D E+E +D G+ D+ E
Sbjct: 137 KLLPQLTYLDGYDREDQEAPDSDAEVDGVDEEE------EDEEGEDEE------DEDDED 184
Query: 193 QEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASSDEDQDGKS 252
E E + +E +D + DE+D E E+ +DE D + ED ++ + E + ++
Sbjct: 185 GEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDEDEEEEEGGKGEKRKRET 244
Query: 253 SSEEEEE 259
E E++
Sbjct: 245 DDEGEDD 251
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 51.2 bits (121), Expect = 1e-06
Identities = 50/207 (24%), Positives = 90/207 (43%), Gaps = 18/207 (8%)
Query: 69 ERAAFPRRLWERVRLSKNYEKALEQIDENLIYWPRFIRHKCKQRFTKITQYLIRIRKLTL 128
ER R ER R + +K + DE Y R + K ++ K Y R++ +
Sbjct: 410 EREREREREREREREREKDKKRDREEDEEDAYERRKLERKLRE---KEAAYQERLKNWEI 466
Query: 129 KRQRKLVPLSKKVERREKRREEKALIAAQLDNAIEKELLERLKQDTYGDIYNFPIHAFDK 188
+ ++K K+ ER E+RR E A A +L KE LE D Y + A K
Sbjct: 467 RERKKTREYEKEAEREEERRREMAKEAKRL-----KEFLEDYDDDRDDPKY-YRGSALQK 520
Query: 189 ALEQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFED--------MDKL 240
L +E E ++ + + K + ++ EE + +R E ++++ E K
Sbjct: 521 RLRDREKEMEADERDRKREKEELEE-IRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQ 579
Query: 241 DASSDEDQDGKSSSEEEEEKALSAKHK 267
+ S+E+++ K EE+ E+ + + +
Sbjct: 580 EPESEEEEEEKQEKEEKREEPMEEEEE 606
Score = 34.7 bits (78), Expect = 0.11
Identities = 47/210 (22%), Positives = 88/210 (41%), Gaps = 21/210 (10%)
Query: 106 RHKCKQRFTKITQYLIRIRKLTLKRQRKLVPLSKKVERREKRREEKALIAAQLDNAIEKE 165
R K + R + + R R+ +R+R+ ++ RE+ +++K ++A E+
Sbjct: 385 REKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERR 444
Query: 166 LLERL---KQDTYGD-IYNFPIHAFDKALEQQEAESDSSDTEEKDDDDDDEEDVGKREFV 221
LER K+ Y + + N+ I K E ++ ++ EE+ + +E +EF+
Sbjct: 445 KLERKLREKEAAYQERLKNWEIRERKKTREYEK----EAEREEERRREMAKEAKRLKEFL 500
Query: 222 EDGEVDESDISDFED-------MDKLDASSDEDQDGKSSSEEEEEKALSAKHKGKMPLRG 274
ED + D D + D+ +++D K EE EE +G
Sbjct: 501 EDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDA 560
Query: 275 PLQR------KRAYVEIEYEQETEPVAKAK 298
LQR +R +I+ E E+E + K
Sbjct: 561 ELQRMEQEAERRRQPQIKQEPESEEEEEEK 590
Score = 31.2 bits (69), Expect = 1.2
Identities = 31/166 (18%), Positives = 66/166 (39%), Gaps = 9/166 (5%)
Query: 124 RKLTLKRQRKLVPLSKKVERREKRREEKALIAAQLDNAIEKELLERLKQDTYGDIYNFPI 183
+++ +R+ + ++ ERRE+ RE + + + E+E +D +
Sbjct: 303 QEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRD 362
Query: 184 HAFDKALEQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDAS 243
D+ +++ + + D + D E +RE + E + + E + +
Sbjct: 363 RERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERERE 422
Query: 244 SDEDQDGKSSSEEEEEKALSAKHKGKMPLRGPLQRKRAYVEIEYEQ 289
+ ++D K EE+EE A R L+RK E Y++
Sbjct: 423 REREKDKKRDREEDEEDAYE---------RRKLERKLREKEAAYQE 459
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 50.4 bits (119), Expect = 2e-06
Identities = 34/119 (28%), Positives = 52/119 (43%), Gaps = 22/119 (18%)
Query: 196 ESDSSDTEEKDDDDDDEEDVGKREFVE---------------------DGEVDESDISDF 234
+ D D E+ +DDDDDEED + E +E + E +E D D
Sbjct: 186 DEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDE 245
Query: 235 EDMDKLDASSDEDQDGKSSSEEEEEKALSAKHKGKMPLRGPLQRKRAYVEIEYEQETEP 293
+D D D D+D+D + EEEEE+ + + GK Q+ + + + TEP
Sbjct: 246 DDDDDEDDEDDDDEDDEEEEEEEEEEPVK-EAPGKRKKEMAKQKAAPEAKKQKVEGTEP 303
Score = 47.4 bits (111), Expect = 2e-05
Identities = 27/105 (25%), Positives = 48/105 (45%)
Query: 188 KALEQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASSDED 247
K ++++++ + D E+D++DD++ED + E + ED D D DED
Sbjct: 138 KNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDED 197
Query: 248 QDGKSSSEEEEEKALSAKHKGKMPLRGPLQRKRAYVEIEYEQETE 292
D + EEE + KGK + + + E E E+E +
Sbjct: 198 DDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDD 242
Score = 39.3 bits (90), Expect = 0.004
Identities = 28/106 (26%), Positives = 45/106 (42%), Gaps = 8/106 (7%)
Query: 187 DKALEQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASSDE 246
D+ + E + D +E +D+D+ E K DE D D +D D+
Sbjct: 146 DEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDD-------EDD 198
Query: 247 DQDGKSSSEEEEEKALSAKHKGKMPLRGPLQRKRAYVEIEYEQETE 292
D D + SEEE + AK K K P++ K + + E++ E
Sbjct: 199 DDDEEDDSEEEAMETTPAKGK-KAAKVVPVKAKNVAEDEDEEEDDE 243
Score = 38.1 bits (87), Expect = 0.010
Identities = 19/65 (29%), Positives = 35/65 (53%)
Query: 191 EQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASSDEDQDG 250
E+++ E + D +E D+DDDDE+D + E E+ V E+ ++M K A+ + +
Sbjct: 238 EEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQK 297
Query: 251 KSSSE 255
+E
Sbjct: 298 VEGTE 302
Score = 35.8 bits (81), Expect = 0.047
Identities = 26/89 (29%), Positives = 43/89 (48%), Gaps = 16/89 (17%)
Query: 182 PIHAFDKALEQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLD 241
P+ A + A ++ E E D + E+ DDD+DDE+D D E DE E+ ++ +
Sbjct: 226 PVKAKNVAEDEDEEEDD--EDEDDDDDEDDEDD--------DDEDDE------EEEEEEE 269
Query: 242 ASSDEDQDGKSSSEEEEEKALSAKHKGKM 270
++ GK E ++KA K K+
Sbjct: 270 EEPVKEAPGKRKKEMAKQKAAPEAKKQKV 298
>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
Length = 740
Score = 49.7 bits (117), Expect = 3e-06
Identities = 42/162 (25%), Positives = 73/162 (45%), Gaps = 29/162 (17%)
Query: 148 REEKALIAAQLDNAIEKELL--------ERLK-----QDTYGDIYNFPIHAFDKALEQQE 194
RE ++L ++LD I K + ER K Q T + P + D
Sbjct: 362 RENRSLAMSRLDEVISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSG 421
Query: 195 AESD---SSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASSDEDQDGK 251
S S+ E DD+DD+E D + E E+ E + +D + ED++++ ++D++
Sbjct: 422 MASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEE-- 479
Query: 252 SSSEEEEEKALSAKHKGKMPLRGPLQRKRAYVEIEYEQETEP 293
E+EEE+A + K K P+ + ++I E+ EP
Sbjct: 480 ---EDEEEEAAAGKDGDKSPM--------SSLQISNEKNLEP 510
Score = 33.1 bits (74), Expect = 0.31
Identities = 19/89 (21%), Positives = 44/89 (49%), Gaps = 7/89 (7%)
Query: 191 EQQEAESDSSDTEEKDD-------DDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDAS 243
E++E E +++D+EE++D +DDEE+ + E + D+S +S + ++ +
Sbjct: 450 EEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLE 509
Query: 244 SDEDQDGKSSSEEEEEKALSAKHKGKMPL 272
+ S ++ + + +S + PL
Sbjct: 510 PGKQISRSSGEQQNKGRIVSPSLLSEEPL 538
>gi|215422388 death-domain associated protein isoform a [Homo
sapiens]
Length = 740
Score = 49.7 bits (117), Expect = 3e-06
Identities = 42/162 (25%), Positives = 73/162 (45%), Gaps = 29/162 (17%)
Query: 148 REEKALIAAQLDNAIEKELL--------ERLK-----QDTYGDIYNFPIHAFDKALEQQE 194
RE ++L ++LD I K + ER K Q T + P + D
Sbjct: 362 RENRSLAMSRLDEVISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSG 421
Query: 195 AESD---SSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASSDEDQDGK 251
S S+ E DD+DD+E D + E E+ E + +D + ED++++ ++D++
Sbjct: 422 MASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEE-- 479
Query: 252 SSSEEEEEKALSAKHKGKMPLRGPLQRKRAYVEIEYEQETEP 293
E+EEE+A + K K P+ + ++I E+ EP
Sbjct: 480 ---EDEEEEAAAGKDGDKSPM--------SSLQISNEKNLEP 510
Score = 33.1 bits (74), Expect = 0.31
Identities = 19/89 (21%), Positives = 44/89 (49%), Gaps = 7/89 (7%)
Query: 191 EQQEAESDSSDTEEKDD-------DDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDAS 243
E++E E +++D+EE++D +DDEE+ + E + D+S +S + ++ +
Sbjct: 450 EEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLE 509
Query: 244 SDEDQDGKSSSEEEEEKALSAKHKGKMPL 272
+ S ++ + + +S + PL
Sbjct: 510 PGKQISRSSGEQQNKGRIVSPSLLSEEPL 538
>gi|215422366 death-domain associated protein isoform b [Homo
sapiens]
Length = 752
Score = 49.7 bits (117), Expect = 3e-06
Identities = 42/162 (25%), Positives = 73/162 (45%), Gaps = 29/162 (17%)
Query: 148 REEKALIAAQLDNAIEKELL--------ERLK-----QDTYGDIYNFPIHAFDKALEQQE 194
RE ++L ++LD I K + ER K Q T + P + D
Sbjct: 374 RENRSLAMSRLDEVISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSG 433
Query: 195 AESD---SSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASSDEDQDGK 251
S S+ E DD+DD+E D + E E+ E + +D + ED++++ ++D++
Sbjct: 434 MASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEE-- 491
Query: 252 SSSEEEEEKALSAKHKGKMPLRGPLQRKRAYVEIEYEQETEP 293
E+EEE+A + K K P+ + ++I E+ EP
Sbjct: 492 ---EDEEEEAAAGKDGDKSPM--------SSLQISNEKNLEP 522
Score = 33.1 bits (74), Expect = 0.31
Identities = 19/89 (21%), Positives = 44/89 (49%), Gaps = 7/89 (7%)
Query: 191 EQQEAESDSSDTEEKDD-------DDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDAS 243
E++E E +++D+EE++D +DDEE+ + E + D+S +S + ++ +
Sbjct: 462 EEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLE 521
Query: 244 SDEDQDGKSSSEEEEEKALSAKHKGKMPL 272
+ S ++ + + +S + PL
Sbjct: 522 PGKQISRSSGEQQNKGRIVSPSLLSEEPL 550
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 48.9 bits (115), Expect = 5e-06
Identities = 24/70 (34%), Positives = 43/70 (61%), Gaps = 3/70 (4%)
Query: 191 EQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASSDEDQDG 250
E+ E E S D +E D+D+++E+ G RE E+ E++E D D ED + ++ +E+++
Sbjct: 103 EEDEGEEYSEDNDEPGDEDEEDEE-GDRE--EEEEIEEEDEDDDEDGEDVEDEEEEEEEE 159
Query: 251 KSSSEEEEEK 260
+ EEEE +
Sbjct: 160 EEEEEEEENE 169
Score = 42.7 bits (99), Expect = 4e-04
Identities = 23/81 (28%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
Query: 181 FPIHAFDKALEQQEAESDSSDTEEKDDDDDDEEDVGKRE-FVEDGEVDESDISDFEDMDK 239
F + A ++++ + + D +EK++D+ +E E ED E +E D + E++++
Sbjct: 78 FAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEE 137
Query: 240 LDASSDEDQDGKSSSEEEEEK 260
D DED + EEEEE+
Sbjct: 138 EDEDDDEDGEDVEDEEEEEEE 158
Score = 40.0 bits (92), Expect = 0.003
Identities = 37/148 (25%), Positives = 67/148 (45%), Gaps = 18/148 (12%)
Query: 136 PLSKKVERREKRREEKA---------LIAAQLDNAIEKELLERL--KQDTYGDIY---NF 181
PL+KK + ++K+ +E A ++ +D + + E + K++ G+ Y N
Sbjct: 56 PLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDND 115
Query: 182 PIHAFDKALEQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFED----M 237
D+ E+ + E + EE +DDD+D EDV E E+ E +E + + ED
Sbjct: 116 EPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNC 175
Query: 238 DKLDASSDEDQDGKSSSEEEEEKALSAK 265
D ++D ++ E + L AK
Sbjct: 176 HNTRIMQDTEKDDNNNDEYDNYDELVAK 203
Score = 34.7 bits (78), Expect = 0.11
Identities = 12/54 (22%), Positives = 34/54 (62%)
Query: 191 EQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASS 244
+++E E + + EE+++++D + + ++D E D+++ ++++ D+L A S
Sbjct: 151 DEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKS 204
Score = 34.3 bits (77), Expect = 0.14
Identities = 20/84 (23%), Positives = 40/84 (47%)
Query: 187 DKALEQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASSDE 246
D+ E++ E D D E+ +D +D+EE+ + E E+ E +E + + + + +
Sbjct: 128 DREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKD 187
Query: 247 DQDGKSSSEEEEEKALSAKHKGKM 270
D + +E A S + GK+
Sbjct: 188 DNNNDEYDNYDELVAKSLLNLGKI 211
>gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear
phosphoprotein 32 family, member B [Homo sapiens]
Length = 272
Score = 47.4 bits (111), Expect = 2e-05
Identities = 31/119 (26%), Positives = 56/119 (47%), Gaps = 15/119 (12%)
Query: 160 NAIEKELLERLKQDTYGDIYNFPIHAFDKALEQQEAESDSSDTEEKDDDDDDEEDV---- 215
N ++ + + L Q T D Y+ D+ +A+ D D EE+D++ +DE+D
Sbjct: 149 NDYQESVFKLLPQLTCLDTYD----PEDQEAPDSDAQVDGVDKEEEDEEGEDEKDXENED 204
Query: 216 GKREFVEDGEVDESDISDFEDMDKLDASS-------DEDQDGKSSSEEEEEKALSAKHK 267
G+ E +++ E ++ D+ +D D++ DED + + EEEEE K
Sbjct: 205 GEEEELDEEEDEDEDVEGDDDKDEVSEEEEEFGLDKDEDDEDEDEDEEEEESGKGENRK 263
Score = 40.8 bits (94), Expect = 0.001
Identities = 21/77 (27%), Positives = 45/77 (58%), Gaps = 6/77 (7%)
Query: 187 DKALEQQEAESDSSDTEEKDDDD----DDEEDVGKREFVEDGEVDESDISDFEDMDKLDA 242
+K E ++ E + D EE +D+D DD+++V + E E+ +D+ + + ED D+ +
Sbjct: 197 EKDXENEDGEEEELDEEEDEDEDVEGDDDKDEVSEEE--EEFGLDKDEDDEDEDEDEEEE 254
Query: 243 SSDEDQDGKSSSEEEEE 259
S + ++ K +++EE+
Sbjct: 255 ESGKGENRKRETDDEED 271
>gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear
phosphoprotein 32 family, member B [Homo sapiens]
Length = 272
Score = 47.4 bits (111), Expect = 2e-05
Identities = 31/119 (26%), Positives = 56/119 (47%), Gaps = 15/119 (12%)
Query: 160 NAIEKELLERLKQDTYGDIYNFPIHAFDKALEQQEAESDSSDTEEKDDDDDDEEDV---- 215
N ++ + + L Q T D Y+ D+ +A+ D D EE+D++ +DE+D
Sbjct: 149 NDYQESVFKLLPQLTCLDTYD----PEDQEAPDSDAQVDGVDKEEEDEEGEDEKDXENED 204
Query: 216 GKREFVEDGEVDESDISDFEDMDKLDASS-------DEDQDGKSSSEEEEEKALSAKHK 267
G+ E +++ E ++ D+ +D D++ DED + + EEEEE K
Sbjct: 205 GEEEELDEEEDEDEDVEGDDDKDEVSEEEEEFGLDKDEDDEDEDEDEEEEESGKGENRK 263
Score = 40.8 bits (94), Expect = 0.001
Identities = 21/77 (27%), Positives = 45/77 (58%), Gaps = 6/77 (7%)
Query: 187 DKALEQQEAESDSSDTEEKDDDD----DDEEDVGKREFVEDGEVDESDISDFEDMDKLDA 242
+K E ++ E + D EE +D+D DD+++V + E E+ +D+ + + ED D+ +
Sbjct: 197 EKDXENEDGEEEELDEEEDEDEDVEGDDDKDEVSEEE--EEFGLDKDEDDEDEDEDEEEE 254
Query: 243 SSDEDQDGKSSSEEEEE 259
S + ++ K +++EE+
Sbjct: 255 ESGKGENRKRETDDEED 271
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 47.4 bits (111), Expect = 2e-05
Identities = 21/82 (25%), Positives = 49/82 (59%), Gaps = 2/82 (2%)
Query: 177 DIYNFPIHAFDKALEQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFED 236
D+ I++ D+ E++E E + + EE++++D +EE+ + E+ E+ E +E + E+
Sbjct: 877 DLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFE--EE 934
Query: 237 MDKLDASSDEDQDGKSSSEEEE 258
++ + +E+++ + EEEE
Sbjct: 935 FEEEEGELEEEEEEEDEEEEEE 956
Score = 42.0 bits (97), Expect = 7e-04
Identities = 19/64 (29%), Positives = 41/64 (64%), Gaps = 1/64 (1%)
Query: 197 SDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASSD-EDQDGKSSSE 255
SD + EE+++++++EE+ + E E+ E DE + + E+ ++ + + E+++G+ E
Sbjct: 886 SDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEE 945
Query: 256 EEEE 259
EEEE
Sbjct: 946 EEEE 949
Score = 41.6 bits (96), Expect = 9e-04
Identities = 20/72 (27%), Positives = 41/72 (56%)
Query: 191 EQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASSDEDQDG 250
E++E E + + EE+++D ++EE+ + F E+ E +E +FE+ + +E++D
Sbjct: 892 EEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDE 951
Query: 251 KSSSEEEEEKAL 262
+ E EE + L
Sbjct: 952 EEEEELEEVEDL 963
Score = 39.7 bits (91), Expect = 0.003
Identities = 19/69 (27%), Positives = 41/69 (59%), Gaps = 2/69 (2%)
Query: 193 QEAESDSSDTEEKDDDDDDEEDVGKREFVEDG--EVDESDISDFEDMDKLDASSDEDQDG 250
+E E + + EE+++++++EED + E E+ E +E + +FE+ + + E+++
Sbjct: 888 EEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEE 947
Query: 251 KSSSEEEEE 259
+ EEEEE
Sbjct: 948 EEDEEEEEE 956
Score = 37.0 bits (84), Expect = 0.021
Identities = 26/106 (24%), Positives = 53/106 (50%), Gaps = 18/106 (16%)
Query: 189 ALEQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASSDEDQ 248
ALE+ + + ++E+++++++EE E+ E +E + DFE+ +ED+
Sbjct: 873 ALEEDLTVININSSDEEEEEEEEEE--------EEEEEEEEEEEDFEE-------EEEDE 917
Query: 249 DGKSSSEEEEEKALSAKHKGKMPLRGPLQRKRAYVEIEYEQETEPV 294
+ EEEEE+ + + + G L+ + + E E+E E V
Sbjct: 918 EEYFEEEEEEEEEFEEEFEEE---EGELEEEEEEEDEEEEEELEEV 960
Score = 35.8 bits (81), Expect = 0.047
Identities = 18/69 (26%), Positives = 41/69 (59%), Gaps = 1/69 (1%)
Query: 191 EQQEAESDSSDTEEKDDDDDDEEDVGKREF-VEDGEVDESDISDFEDMDKLDASSDEDQD 249
E+++ E + D EE +++++EE+ + EF E+GE++E + + E+ ++ ++ +
Sbjct: 906 EEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEF 965
Query: 250 GKSSSEEEE 258
G + E EE
Sbjct: 966 GTAGGEVEE 974
Score = 30.4 bits (67), Expect = 2.0
Identities = 17/75 (22%), Positives = 42/75 (56%), Gaps = 5/75 (6%)
Query: 187 DKALEQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASSDE 246
++ E++E + + EE++++++ EE+ + E + E +E D + E+++++ E
Sbjct: 907 EEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEV-----E 961
Query: 247 DQDGKSSSEEEEEKA 261
D + ++ E EE A
Sbjct: 962 DLEFGTAGGEVEEGA 976
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 47.0 bits (110), Expect = 2e-05
Identities = 34/107 (31%), Positives = 49/107 (45%), Gaps = 6/107 (5%)
Query: 187 DKALEQQEAESDSSDTEEKDDDDDDEE--DVGKREF-VEDGEVDESDISDFEDMDKLDAS 243
++A ++ +E D D EE ++D+D EE D K+E V DGE +ESD S L A
Sbjct: 966 EEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSS---SKCSLYAD 1022
Query: 244 SDEDQDGKSSSEEEEEKALSAKHKGKMPLRGPLQRKRAYVEIEYEQE 290
SD + D S SE + S+ + E E E+E
Sbjct: 1023 SDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEE 1069
Score = 42.7 bits (99), Expect = 4e-04
Identities = 35/123 (28%), Positives = 54/123 (43%), Gaps = 37/123 (30%)
Query: 191 EQQEAESDSSDTEEKDDDDDDEEDVGKREFVE---------DGEVDESDISD----FEDM 237
E +EA +SS ++++DD++DEED + E V+ DGE +ESD S + D
Sbjct: 964 EGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADS 1023
Query: 238 D-KLDASSDEDQDGKSSS-----------------------EEEEEKALSAKHKGKMPLR 273
D + D++SD + SSS EEEEE+ + P
Sbjct: 1024 DGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPRE 1083
Query: 274 GPL 276
P+
Sbjct: 1084 VPV 1086
>gi|106507301 DNA-directed DNA polymerase alpha 1 [Homo sapiens]
Length = 1462
Score = 47.0 bits (110), Expect = 2e-05
Identities = 36/114 (31%), Positives = 61/114 (53%), Gaps = 18/114 (15%)
Query: 147 RREEKALIAAQLDNAIEKELLERLKQDTYGDIYNFPIHAFDKALEQQEAESDSSDTEEKD 206
RRE+K+ Q E LERLK+ G+ Y + + F E+ + E S + +
Sbjct: 22 RREKKSKKGRQ-------EALERLKKAKAGEKYKYEVEDFTGVYEEVDEEQYSKLVQARQ 74
Query: 207 DDD--DDEEDVGKREFVEDG-EVDESDISDFEDMDKLDASSDEDQDGKSSSEEE 257
DDD D++ +G +VEDG E+ + D+ D D LDA ++ +DGK+ ++++
Sbjct: 75 DDDWIVDDDGIG---YVEDGREIFDDDLED----DALDA-DEKGKDGKARNKDK 120
>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
Length = 1390
Score = 46.6 bits (109), Expect = 3e-05
Identities = 42/179 (23%), Positives = 80/179 (44%), Gaps = 22/179 (12%)
Query: 105 IRHKCK--QRFTKITQYLIRIRKLTLKRQRKLVPLSK-KVERREKRREEKALIAAQLDNA 161
+R C+ R++ + Q ++ + +T + L + K RR++ RE + L + N
Sbjct: 154 VRRSCRIRSRYSGVNQSMLFDKLITNTAEAVLQKMDDMKKMRRQRMRELEDL---GVFNE 210
Query: 162 IEKELLERLKQDTYGDIYNFPIHAFDKALEQQEAESDSSDTEEKDDDDDDEEDVGKREFV 221
E+ L + DI ++ + QE +SS+ E + +DD ED
Sbjct: 211 TEESNLNMYTRGKQKDIQRTD----EETTDNQEGSVESSEEGEDQEHEDDGED------- 259
Query: 222 EDGEVDESDISDFEDMDKLDASSDEDQDGKSSSEEEEEKALSAKHKGKMPLRGPLQRKR 280
ED E D+ D D +D D ++D+D + EE +++ + K + + PL++ R
Sbjct: 260 EDDEDDDDDDDDDDDDD-----DEDDEDEEDGEEENQKRYYLRQRKATVYYQAPLEKPR 313
Score = 28.9 bits (63), Expect = 5.8
Identities = 44/237 (18%), Positives = 87/237 (36%), Gaps = 45/237 (18%)
Query: 38 LCNRSSCPLANSQYATIKEEKGQCYLYMKVIERAAFPRRLWERVRLSKNYEKALEQIDEN 97
L +C L ++ YA IKEE L +++E+ E+I E+
Sbjct: 1073 LIRHRACALRDTAYAIIKEE-------------------------LDEDFEQLCEEIQES 1107
Query: 98 LIYWPRFIRHKCKQRFTKITQYLIRIRKLTLKRQRKLVPLSKKVERREKRREEKALIAAQ 157
R R ++ +++ + TL ++ P E+ EK + +A
Sbjct: 1108 -----RKKRGCSSSKYAPSYYHVMPKQNSTLVGDKRSDP-----EQNEKLKTPSTPVACS 1157
Query: 158 LDNAIEKELLERLKQDTYGDIYNFPIHAFDKALEQQEAESDSSDT-EEKDDDDDDEEDVG 216
+++++ ++ N+ + K + +A+ DS + + K + D +E
Sbjct: 1158 TPAQLKRKIRKK---------SNWYLGTIKKRRKISQAKDDSQNAIDHKIESDTEETQDT 1208
Query: 217 KREFVEDGEVDESDISDFEDMDKLDASSDEDQDGKSSSEEEEEKALSAKHKGKMPLR 273
+ E G ES + + E S E ++ ++ E E S K LR
Sbjct: 1209 SVDHNETGNTGESSVEENEKQQNASESKLELRNNSNTCNIENELEDSRKTTACTELR 1265
>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
Length = 330
Score = 46.2 bits (108), Expect = 3e-05
Identities = 24/88 (27%), Positives = 45/88 (51%), Gaps = 4/88 (4%)
Query: 188 KALEQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASSDED 247
KA+ + D E + +++D++ED+ K + ED + D++D+S + LDAS +ED
Sbjct: 137 KAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKY----NLDASEEED 192
Query: 248 QDGKSSSEEEEEKALSAKHKGKMPLRGP 275
+ K S+ K+ S+ + P
Sbjct: 193 SNKKKSNRRSRSKSRSSHSRSSSRSSSP 220
>gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]
Length = 320
Score = 46.2 bits (108), Expect = 3e-05
Identities = 24/88 (27%), Positives = 45/88 (51%), Gaps = 4/88 (4%)
Query: 188 KALEQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASSDED 247
KA+ + D E + +++D++ED+ K + ED + D++D+S + LDAS +ED
Sbjct: 137 KAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKY----NLDASEEED 192
Query: 248 QDGKSSSEEEEEKALSAKHKGKMPLRGP 275
+ K S+ K+ S+ + P
Sbjct: 193 SNKKKSNRRSRSKSRSSHSRSSSRSSSP 220
>gi|42740903 MTERF domain containing 2 [Homo sapiens]
Length = 381
Score = 45.8 bits (107), Expect = 5e-05
Identities = 33/112 (29%), Positives = 60/112 (53%), Gaps = 23/112 (20%)
Query: 157 QLDNAIEKELL-----ERLKQDTYGDIYNFPIHAFDKALEQQEAESDSSDTEEK----DD 207
Q+ N + K++L E L + + F + F K L ++E ES+SS +++K D+
Sbjct: 284 QIPNPLLKDILRVSEAEFLARTACTSVEEFQV--FKKLLAREEEESESSTSDDKRASLDE 341
Query: 208 DDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASSDEDQDGKSSSEEEEE 259
D+DD+++ ED + D++D D ++ D +DED+D ++EEE
Sbjct: 342 DEDDDDE-------EDNDEDDNDEDDDDEDDDEAEDNDEDED-----DDEEE 381
>gi|115529449 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 45.8 bits (107), Expect = 5e-05
Identities = 28/82 (34%), Positives = 41/82 (50%), Gaps = 9/82 (10%)
Query: 192 QQEAESDSSDTEEKDDDDDD--EEDVGKREFVEDG-------EVDESDISDFEDMDKLDA 242
Q ++ES+ D E++DD+D+D EED + EDG DES+ D + D D
Sbjct: 635 QSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDE 694
Query: 243 SSDEDQDGKSSSEEEEEKALSA 264
DED D +E E + S+
Sbjct: 695 DDDEDDDEDEDNESEGSSSSSS 716
Score = 41.6 bits (96), Expect = 9e-04
Identities = 17/69 (24%), Positives = 35/69 (50%)
Query: 191 EQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASSDEDQDG 250
+ + E D D +++D+D+++E+D + G+ ES D + + DED+D
Sbjct: 637 KSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDD 696
Query: 251 KSSSEEEEE 259
+E+E+
Sbjct: 697 DEDDDEDED 705
Score = 38.9 bits (89), Expect = 0.006
Identities = 20/64 (31%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
Query: 191 EQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASSDEDQDG 250
++ E E D + + +D D E + E EDG+ +E D D +D + D D + +G
Sbjct: 652 DEDEEEEDDENGDSSEDGGDSSESSSEDE-SEDGDENEEDDEDEDDDEDDDEDEDNESEG 710
Query: 251 KSSS 254
SSS
Sbjct: 711 SSSS 714
Score = 38.5 bits (88), Expect = 0.007
Identities = 41/182 (22%), Positives = 79/182 (43%), Gaps = 26/182 (14%)
Query: 78 WERVRLSK--NYEK-ALEQIDENLIYWPRFIRHKCKQRFTKITQYLIRIRKLTLKRQRKL 134
W+R+ S+ +Y+K A EQ + ++ +++ Q +Y+ RK ++ + R
Sbjct: 567 WQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRK-SMTKLRGP 625
Query: 135 VPLSKKVERREKRREEKALIAAQLDNAIEKELLERLKQDTYGDIYNFPIHAFDKALEQQE 194
P S + + K E+ ++ +++ E + D GD + E
Sbjct: 626 NPKSSRTTLQSKSESEED----DEEDEDDEDEDEEEEDDENGD-----------SSEDGG 670
Query: 195 AESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASSDEDQDGKSSS 254
S+SS +E +D D++EED ++ E D+ D + ED + +SS G SS
Sbjct: 671 DSSESSSEDESEDGDENEED-------DEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSD 723
Query: 255 EE 256
+
Sbjct: 724 SD 725
Score = 35.8 bits (81), Expect = 0.047
Identities = 21/67 (31%), Positives = 38/67 (56%), Gaps = 2/67 (2%)
Query: 196 ESDSSDTEEKDDD-DDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASS-DEDQDGKSS 253
+S + + K + +DDEED + E+ E DE+ S + D ++SS DE +DG +
Sbjct: 628 KSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDEN 687
Query: 254 SEEEEEK 260
E++E++
Sbjct: 688 EEDDEDE 694
>gi|115529451 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 45.8 bits (107), Expect = 5e-05
Identities = 28/82 (34%), Positives = 41/82 (50%), Gaps = 9/82 (10%)
Query: 192 QQEAESDSSDTEEKDDDDDD--EEDVGKREFVEDG-------EVDESDISDFEDMDKLDA 242
Q ++ES+ D E++DD+D+D EED + EDG DES+ D + D D
Sbjct: 635 QSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDE 694
Query: 243 SSDEDQDGKSSSEEEEEKALSA 264
DED D +E E + S+
Sbjct: 695 DDDEDDDEDEDNESEGSSSSSS 716
Score = 41.6 bits (96), Expect = 9e-04
Identities = 17/69 (24%), Positives = 35/69 (50%)
Query: 191 EQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASSDEDQDG 250
+ + E D D +++D+D+++E+D + G+ ES D + + DED+D
Sbjct: 637 KSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDD 696
Query: 251 KSSSEEEEE 259
+E+E+
Sbjct: 697 DEDDDEDED 705
Score = 38.9 bits (89), Expect = 0.006
Identities = 20/64 (31%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
Query: 191 EQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASSDEDQDG 250
++ E E D + + +D D E + E EDG+ +E D D +D + D D + +G
Sbjct: 652 DEDEEEEDDENGDSSEDGGDSSESSSEDE-SEDGDENEEDDEDEDDDEDDDEDEDNESEG 710
Query: 251 KSSS 254
SSS
Sbjct: 711 SSSS 714
Score = 38.5 bits (88), Expect = 0.007
Identities = 41/182 (22%), Positives = 79/182 (43%), Gaps = 26/182 (14%)
Query: 78 WERVRLSK--NYEK-ALEQIDENLIYWPRFIRHKCKQRFTKITQYLIRIRKLTLKRQRKL 134
W+R+ S+ +Y+K A EQ + ++ +++ Q +Y+ RK ++ + R
Sbjct: 567 WQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRK-SMTKLRGP 625
Query: 135 VPLSKKVERREKRREEKALIAAQLDNAIEKELLERLKQDTYGDIYNFPIHAFDKALEQQE 194
P S + + K E+ ++ +++ E + D GD + E
Sbjct: 626 NPKSSRTTLQSKSESEED----DEEDEDDEDEDEEEEDDENGD-----------SSEDGG 670
Query: 195 AESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASSDEDQDGKSSS 254
S+SS +E +D D++EED ++ E D+ D + ED + +SS G SS
Sbjct: 671 DSSESSSEDESEDGDENEED-------DEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSD 723
Query: 255 EE 256
+
Sbjct: 724 SD 725
Score = 35.8 bits (81), Expect = 0.047
Identities = 21/67 (31%), Positives = 38/67 (56%), Gaps = 2/67 (2%)
Query: 196 ESDSSDTEEKDDD-DDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASS-DEDQDGKSS 253
+S + + K + +DDEED + E+ E DE+ S + D ++SS DE +DG +
Sbjct: 628 KSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDEN 687
Query: 254 SEEEEEK 260
E++E++
Sbjct: 688 EEDDEDE 694
>gi|7657671 upstream binding transcription factor, RNA polymerase I
isoform a [Homo sapiens]
Length = 764
Score = 45.8 bits (107), Expect = 5e-05
Identities = 28/82 (34%), Positives = 41/82 (50%), Gaps = 9/82 (10%)
Query: 192 QQEAESDSSDTEEKDDDDDD--EEDVGKREFVEDG-------EVDESDISDFEDMDKLDA 242
Q ++ES+ D E++DD+D+D EED + EDG DES+ D + D D
Sbjct: 672 QSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDE 731
Query: 243 SSDEDQDGKSSSEEEEEKALSA 264
DED D +E E + S+
Sbjct: 732 DDDEDDDEDEDNESEGSSSSSS 753
Score = 41.6 bits (96), Expect = 9e-04
Identities = 17/69 (24%), Positives = 35/69 (50%)
Query: 191 EQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASSDEDQDG 250
+ + E D D +++D+D+++E+D + G+ ES D + + DED+D
Sbjct: 674 KSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDD 733
Query: 251 KSSSEEEEE 259
+E+E+
Sbjct: 734 DEDDDEDED 742
Score = 38.9 bits (89), Expect = 0.006
Identities = 20/64 (31%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
Query: 191 EQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASSDEDQDG 250
++ E E D + + +D D E + E EDG+ +E D D +D + D D + +G
Sbjct: 689 DEDEEEEDDENGDSSEDGGDSSESSSEDE-SEDGDENEEDDEDEDDDEDDDEDEDNESEG 747
Query: 251 KSSS 254
SSS
Sbjct: 748 SSSS 751
Score = 38.5 bits (88), Expect = 0.007
Identities = 41/182 (22%), Positives = 79/182 (43%), Gaps = 26/182 (14%)
Query: 78 WERVRLSK--NYEK-ALEQIDENLIYWPRFIRHKCKQRFTKITQYLIRIRKLTLKRQRKL 134
W+R+ S+ +Y+K A EQ + ++ +++ Q +Y+ RK ++ + R
Sbjct: 604 WQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRK-SMTKLRGP 662
Query: 135 VPLSKKVERREKRREEKALIAAQLDNAIEKELLERLKQDTYGDIYNFPIHAFDKALEQQE 194
P S + + K E+ ++ +++ E + D GD + E
Sbjct: 663 NPKSSRTTLQSKSESEED----DEEDEDDEDEDEEEEDDENGD-----------SSEDGG 707
Query: 195 AESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASSDEDQDGKSSS 254
S+SS +E +D D++EED ++ E D+ D + ED + +SS G SS
Sbjct: 708 DSSESSSEDESEDGDENEED-------DEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSD 760
Query: 255 EE 256
+
Sbjct: 761 SD 762
Score = 35.8 bits (81), Expect = 0.047
Identities = 21/67 (31%), Positives = 38/67 (56%), Gaps = 2/67 (2%)
Query: 196 ESDSSDTEEKDDD-DDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASS-DEDQDGKSS 253
+S + + K + +DDEED + E+ E DE+ S + D ++SS DE +DG +
Sbjct: 665 KSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDEN 724
Query: 254 SEEEEEK 260
E++E++
Sbjct: 725 EEDDEDE 731
>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
Length = 2803
Score = 45.4 bits (106), Expect = 6e-05
Identities = 37/140 (26%), Positives = 64/140 (45%), Gaps = 10/140 (7%)
Query: 129 KRQRKLVPLSKKVERREKRREEKALIAAQLDNAIEKELLERLKQDTYGDIYNFPIHAFDK 188
++ + L P K +E ++K E+K I + D A+E ++DT + + + DK
Sbjct: 1424 QKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALE-------QKDTALEQKDKALEPKDK 1476
Query: 189 ALEQQE--AESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASSDE 246
LEQ++ E EEKD D + + + ED + D D E DK +
Sbjct: 1477 DLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKD-RDLEQTDKAPEQKHQ 1535
Query: 247 DQDGKSSSEEEEEKALSAKH 266
Q+ K E++++AL K+
Sbjct: 1536 AQEQKDKVSEKKDQALEQKY 1555
Score = 35.4 bits (80), Expect = 0.062
Identities = 33/141 (23%), Positives = 64/141 (45%), Gaps = 16/141 (11%)
Query: 127 TLKRQRKLVPLSKKVERREKRREEKALIAAQLDNAIEKELLERLKQDTYGDIYNFPIHAF 186
TL+ + + P + ++++ K Q D A+E++ + ++DT +
Sbjct: 1373 TLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDT-------ALEQK 1425
Query: 187 DKALEQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASSDE 246
DKALE ++ D EEKD + ++ + + +D +++ D + E DK D+
Sbjct: 1426 DKALEPKD-----KDLEEKDKALEQKDKIPEE---KDKALEQKDTA-LEQKDKALEPKDK 1476
Query: 247 DQDGKSSSEEEEEKALSAKHK 267
D + K E++EK K K
Sbjct: 1477 DLEQKDRVLEQKEKIPEEKDK 1497
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 45.1 bits (105), Expect = 8e-05
Identities = 41/195 (21%), Positives = 87/195 (44%), Gaps = 10/195 (5%)
Query: 110 KQRFTKITQYLIRIRKLTLKRQRKLVPLSKKVERREK---RREEKALIAAQLDNAIEKE- 165
+ TK + L R ++ + R+++ +K+ E R+ + ++ + + IE+E
Sbjct: 2129 RSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEE 2188
Query: 166 ----LLERLKQDTYGDIYNFPIHAFDKALEQQEAESD-SSDTEEKDDDDDDEEDVGKREF 220
L R ++ + P F +++ E+E S + E D+ + +E + E
Sbjct: 2189 VIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEE 2248
Query: 221 VEDGEVDESDISDFEDMDKLDASSDEDQDGKSSSEEEEEKALSAKHKGKMPLRGPLQRKR 280
E E +E + + + ++ + +E+ + K +EEEEK K K K ++ +
Sbjct: 2249 EEREEEEEREEEEVREEEE-ERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFE 2307
Query: 281 AYVEIEYEQETEPVA 295
EI E+ETE ++
Sbjct: 2308 EKEEIMSEEETESLS 2322
Score = 37.0 bits (84), Expect = 0.021
Identities = 25/90 (27%), Positives = 49/90 (54%), Gaps = 10/90 (11%)
Query: 187 DKALEQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKL------ 240
++ E++E + + EEK + ++EE K++ + EV E + FE+ +++
Sbjct: 2260 EEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKE-EVFEEKEEIMSEEET 2318
Query: 241 DASSDEDQDGKSSSEEEE---EKALSAKHK 267
++ SDE+++ +S S EEE EK + K K
Sbjct: 2319 ESLSDEEEEEESCSLEEEVDREKEILKKEK 2348
Score = 29.3 bits (64), Expect = 4.4
Identities = 19/81 (23%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Query: 87 YEKALEQIDENLIYWPRFIRHKCKQRFTKITQYLIRIRKLTLKRQRKLVPLSKKVERREK 146
+ K L Q++E L + K K++ + + L+++ K+Q KL K+ +
Sbjct: 1884 FNKILAQVEEKLTQEKETVIKK-KEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKA 1942
Query: 147 RREEKALIAAQLDNAIEKELL 167
+ K + +LD A E++ L
Sbjct: 1943 MVQGKKRLRGELDIAKEEKAL 1963
>gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32
family, member E isoform 2 [Homo sapiens]
Length = 227
Score = 45.1 bits (105), Expect = 8e-05
Identities = 42/147 (28%), Positives = 69/147 (46%), Gaps = 19/147 (12%)
Query: 121 IRIRKLTLKRQRKLVPLSKKVERREKRREEKALIAAQLDNAIE--KELLERLKQDTYGDI 178
+ + + L +L L+K ++ K + L ++ N + + + E L+Q TY D
Sbjct: 47 LSMANVELSSLARLPSLNKLRKQNLKNLKSLDLFNCEITNLEDYRESIFELLQQITYLD- 105
Query: 179 YNFPIHAFDKALEQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMD 238
FD+ E EA DS + +++D D+DDEE+ +G +E + + ED D
Sbjct: 106 ------GFDQ--EDNEAP-DSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDED 156
Query: 239 KLDASSDEDQD--GKSSSEEEEEKALS 263
+ DED+D G E EEE LS
Sbjct: 157 E-----DEDEDEAGSELGEGEEEVGLS 178
Score = 37.0 bits (84), Expect = 0.021
Identities = 26/88 (29%), Positives = 41/88 (46%), Gaps = 8/88 (9%)
Query: 187 DKALEQQEA-------ESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDK 239
D+ E+ EA E + + EE +D+D+DE++ G + EV S + E D+
Sbjct: 129 DEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDE 188
Query: 240 LDASSDEDQDGKSSSEEEEEKALSAKHK 267
D D ++G+ EEEE K K
Sbjct: 189 ED-DDDYVEEGEEEEEEEEGGLRGEKRK 215
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 45.1 bits (105), Expect = 8e-05
Identities = 27/90 (30%), Positives = 45/90 (50%), Gaps = 3/90 (3%)
Query: 187 DKALEQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASSDE 246
D + + DS++ EE+DD+++DEED E D ESD + D + + D+
Sbjct: 595 DSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDE--SDDSQSESDSNSESDTEGSEEEDDD 652
Query: 247 DQD-GKSSSEEEEEKALSAKHKGKMPLRGP 275
D+D +S S+ E EK +K ++ P
Sbjct: 653 DKDQDESDSDTEGEKTSMKLNKTTSSVKSP 682
Score = 37.0 bits (84), Expect = 0.021
Identities = 36/156 (23%), Positives = 65/156 (41%), Gaps = 10/156 (6%)
Query: 137 LSKKVERREKRREEKALIAAQLDNAIEKELLERLKQDTYGDI------YNFPIHAFDKAL 190
+ K ++ R +K ++ +L + K+DT G I + +
Sbjct: 1231 IDKNIDYMSNLRRDKWVVEGKLRKLRIIHAKKTGKRDTSGGIDLGEEQHPLGTPTPGRKR 1290
Query: 191 EQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASSD--EDQ 248
++ +SD D ++ D DD +ED E ED + ++DI + ED AS + E Q
Sbjct: 1291 RRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAASVEELEKQ 1350
Query: 249 DGKSSSEEEE--EKALSAKHKGKMPLRGPLQRKRAY 282
K S ++ + K A H + + G + +R Y
Sbjct: 1351 IEKLSKQQSQYRRKLFDASHSLRSVMFGQDRYRRRY 1386
Score = 34.7 bits (78), Expect = 0.11
Identities = 25/89 (28%), Positives = 43/89 (48%), Gaps = 14/89 (15%)
Query: 188 KALEQQE-AESDS---SDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDK---- 239
KA+E ++SDS SDT + D +D+ + E ED ++ES+ D + +
Sbjct: 237 KAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEEDQSIEESEDDDSDSESEAQHK 296
Query: 240 ------LDASSDEDQDGKSSSEEEEEKAL 262
L SD DG+ ++E+ +EK +
Sbjct: 297 SNNQVLLHGISDPKADGQKATEKAQEKRI 325
Score = 30.0 bits (66), Expect = 2.6
Identities = 13/78 (16%), Positives = 34/78 (43%)
Query: 180 NFPIHAFDKALEQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDK 239
N P+ A ++ ++ + ++ D D E + + D+ + + E+
Sbjct: 219 NQPLDARVDKIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEEDQS 278
Query: 240 LDASSDEDQDGKSSSEEE 257
++ S D+D D +S ++ +
Sbjct: 279 IEESEDDDSDSESEAQHK 296
>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 44.7 bits (104), Expect = 1e-04
Identities = 35/145 (24%), Positives = 69/145 (47%), Gaps = 11/145 (7%)
Query: 126 LTLKRQRKLVPLSKKVERREKRREEKALIAAQLDNAIEKELLER-LKQDTYGDIYNFPIH 184
L + + ++ P + E ++ ++ Q ++ E+E E L++D + +H
Sbjct: 525 LNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELH 584
Query: 185 AFDKALEQQEAESDSSDTEEKDDDDDD--EEDVGKREFVEDGEVDESDISDFEDMDKLDA 242
+ L+++ E+DS ++E +DD + +E+ +REF ED + E E+ D +
Sbjct: 585 --ENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKE------EEEDTYEK 636
Query: 243 SSDEDQDGKSSSEEEEEKALSAKHK 267
D++ D K E +EK L A K
Sbjct: 637 VFDDESDEKEDEEYADEKGLEAADK 661
Score = 40.0 bits (92), Expect = 0.003
Identities = 30/124 (24%), Positives = 59/124 (47%), Gaps = 19/124 (15%)
Query: 171 KQDTYGDIYNFPI-------HAFDKALEQQEAESDSSDTEEK----DDDDDDEEDVGKRE 219
++DTY +++ +A +K LE + +++ D +EK DD +DE+ GK
Sbjct: 630 EEDTYEKVFDDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDEDADGK-- 687
Query: 220 FVEDGEVDESDISDFEDMDKLDASSDEDQDGKSSSEEEEEKALSAKHKGKMPLRGPLQRK 279
EV+++D FED D + DE++D ++ ++ + G + GPL
Sbjct: 688 -----EVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDDSDERGTLGGFGSVE-EGPLSTG 741
Query: 280 RAYV 283
+++
Sbjct: 742 SSFI 745
Score = 39.3 bits (90), Expect = 0.004
Identities = 32/130 (24%), Positives = 58/130 (44%), Gaps = 20/130 (15%)
Query: 145 EKRREEKALIAAQLDNAIEKELLERLKQDTYGDIYNFPIHAFDKALEQQEAESD-SSDTE 203
EK +E+ +N ++KEL E +++ F +K L+++ +E + D++
Sbjct: 571 EKDLDEEGSEKELHENVLDKELEENDSENS-----EFEDDGSEKVLDEEGSEREFDEDSD 625
Query: 204 EKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKL--------------DASSDEDQD 249
EK++++D E V E E + + +D E DK D DED D
Sbjct: 626 EKEEEEDTYEKVFDDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDEDAD 685
Query: 250 GKSSSEEEEE 259
GK + +E+
Sbjct: 686 GKEVEDADEK 695
Score = 33.9 bits (76), Expect = 0.18
Identities = 22/76 (28%), Positives = 34/76 (44%), Gaps = 2/76 (2%)
Query: 187 DKALEQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASSDE 246
D ++ + ++ +D EE + E+D+ K E G ES+ D E D S +
Sbjct: 497 DSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQ 556
Query: 247 DQDGKSSSEEEEEKAL 262
+DG S E EE L
Sbjct: 557 SEDG--SEREFEENGL 570
>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 44.7 bits (104), Expect = 1e-04
Identities = 35/145 (24%), Positives = 69/145 (47%), Gaps = 11/145 (7%)
Query: 126 LTLKRQRKLVPLSKKVERREKRREEKALIAAQLDNAIEKELLER-LKQDTYGDIYNFPIH 184
L + + ++ P + E ++ ++ Q ++ E+E E L++D + +H
Sbjct: 525 LNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELH 584
Query: 185 AFDKALEQQEAESDSSDTEEKDDDDDD--EEDVGKREFVEDGEVDESDISDFEDMDKLDA 242
+ L+++ E+DS ++E +DD + +E+ +REF ED + E E+ D +
Sbjct: 585 --ENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKE------EEEDTYEK 636
Query: 243 SSDEDQDGKSSSEEEEEKALSAKHK 267
D++ D K E +EK L A K
Sbjct: 637 VFDDESDEKEDEEYADEKGLEAADK 661
Score = 40.0 bits (92), Expect = 0.003
Identities = 30/124 (24%), Positives = 59/124 (47%), Gaps = 19/124 (15%)
Query: 171 KQDTYGDIYNFPI-------HAFDKALEQQEAESDSSDTEEK----DDDDDDEEDVGKRE 219
++DTY +++ +A +K LE + +++ D +EK DD +DE+ GK
Sbjct: 630 EEDTYEKVFDDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDEDADGK-- 687
Query: 220 FVEDGEVDESDISDFEDMDKLDASSDEDQDGKSSSEEEEEKALSAKHKGKMPLRGPLQRK 279
EV+++D FED D + DE++D ++ ++ + G + GPL
Sbjct: 688 -----EVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDDSDERGTLGGFGSVE-EGPLSTG 741
Query: 280 RAYV 283
+++
Sbjct: 742 SSFI 745
Score = 39.3 bits (90), Expect = 0.004
Identities = 32/130 (24%), Positives = 58/130 (44%), Gaps = 20/130 (15%)
Query: 145 EKRREEKALIAAQLDNAIEKELLERLKQDTYGDIYNFPIHAFDKALEQQEAESD-SSDTE 203
EK +E+ +N ++KEL E +++ F +K L+++ +E + D++
Sbjct: 571 EKDLDEEGSEKELHENVLDKELEENDSENS-----EFEDDGSEKVLDEEGSEREFDEDSD 625
Query: 204 EKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKL--------------DASSDEDQD 249
EK++++D E V E E + + +D E DK D DED D
Sbjct: 626 EKEEEEDTYEKVFDDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDEDAD 685
Query: 250 GKSSSEEEEE 259
GK + +E+
Sbjct: 686 GKEVEDADEK 695
Score = 33.9 bits (76), Expect = 0.18
Identities = 22/76 (28%), Positives = 34/76 (44%), Gaps = 2/76 (2%)
Query: 187 DKALEQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASSDE 246
D ++ + ++ +D EE + E+D+ K E G ES+ D E D S +
Sbjct: 497 DSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQ 556
Query: 247 DQDGKSSSEEEEEKAL 262
+DG S E EE L
Sbjct: 557 SEDG--SEREFEENGL 570
>gi|115529475 polymerase (RNA) III (DNA directed) polypeptide G
(32kD) [Homo sapiens]
Length = 223
Score = 44.7 bits (104), Expect = 1e-04
Identities = 22/65 (33%), Positives = 39/65 (60%), Gaps = 2/65 (3%)
Query: 187 DKALEQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDI--SDFEDMDKLDASS 244
+K+ E+ E + S + ++ DDDDD++ + E+ E+ + +E+D S FED D A S
Sbjct: 155 EKSDEENEEKEGSKEKSKEGDDDDDDDAAEQEEYDEEEQEEENDYINSYFEDGDDFGADS 214
Query: 245 DEDQD 249
D++ D
Sbjct: 215 DDNMD 219
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 44.3 bits (103), Expect = 1e-04
Identities = 27/116 (23%), Positives = 58/116 (50%), Gaps = 9/116 (7%)
Query: 189 ALEQQEAESDSSDTEEKDDDDDDEEDVGKREFV---------EDGEVDESDISDFEDMDK 239
A+ +E + ++++ +E++ + ++EE K+ V E+GE +E + + E+ +
Sbjct: 481 AVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEED 540
Query: 240 LDASSDEDQDGKSSSEEEEEKALSAKHKGKMPLRGPLQRKRAYVEIEYEQETEPVA 295
A SD+ ++G S E EK + +G+ + A E + E+++E VA
Sbjct: 541 EGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVA 596
Score = 38.5 bits (88), Expect = 0.007
Identities = 41/182 (22%), Positives = 81/182 (44%), Gaps = 22/182 (12%)
Query: 128 LKRQRKLVPLSKKVERREKRREEKALIAAQLDNAIEKELLERLKQDTYGDIYNFPIHAFD 187
LK Q K V +++ K +EK+ + L AI +EL +K++ A +
Sbjct: 446 LKVQHKFV---EEIIEETKVEDEKSEMEEAL-TAITEELAVSMKEEKK--------EAAE 493
Query: 188 KALEQQEAESD----------SSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDM 237
+ E+ EAE + ++ E K+++ + EE+ G+ E E+ E +SD ++
Sbjct: 494 EKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGS 553
Query: 238 DKLDASSDEDQDGKSSSEEEEEKALSAKHKGKMPLRGPLQRKRAYVEIEYEQETEPVAKA 297
+K +S E+ + + E E + A+ K + + + E+ + + E KA
Sbjct: 554 EKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKA 613
Query: 298 KT 299
K+
Sbjct: 614 KS 615
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.131 0.367
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,010,586
Number of Sequences: 37866
Number of extensions: 535131
Number of successful extensions: 12099
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 414
Number of HSP's successfully gapped in prelim test: 511
Number of HSP's that attempted gapping in prelim test: 4850
Number of HSP's gapped (non-prelim): 3975
length of query: 300
length of database: 18,247,518
effective HSP length: 102
effective length of query: 198
effective length of database: 14,385,186
effective search space: 2848266828
effective search space used: 2848266828
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.