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Search of human proteins with 31377611
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31377611 coiled-coil domain containing 148 [Homo sapiens]
(591 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31377611 coiled-coil domain containing 148 [Homo sapiens] 1180 0.0
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 80 5e-15
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 70 7e-12
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 68 2e-11
gi|94680976 coiled-coil domain containing 112 isoform 1 [Homo sa... 68 2e-11
gi|145580595 coiled-coil domain containing 112 isoform 2 [Homo s... 68 2e-11
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 66 8e-11
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 65 1e-10
gi|148746195 trichohyalin [Homo sapiens] 65 1e-10
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 65 2e-10
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 64 4e-10
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 64 5e-10
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 64 5e-10
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 63 9e-10
gi|71061468 centromere protein E [Homo sapiens] 62 1e-09
gi|109134347 NY-REN-58 antigen [Homo sapiens] 62 1e-09
gi|109134355 NY-REN-58 antigen [Homo sapiens] 62 1e-09
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 62 2e-09
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 61 3e-09
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 61 3e-09
gi|38044112 restin isoform b [Homo sapiens] 60 4e-09
gi|4506751 restin isoform a [Homo sapiens] 60 4e-09
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 60 4e-09
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 60 4e-09
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 60 4e-09
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 60 4e-09
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 60 4e-09
gi|221219020 NYD-SP11 protein [Homo sapiens] 60 6e-09
gi|118498356 kinectin 1 isoform a [Homo sapiens] 60 6e-09
gi|118498368 kinectin 1 isoform c [Homo sapiens] 60 6e-09
>gi|31377611 coiled-coil domain containing 148 [Homo sapiens]
Length = 591
Score = 1180 bits (3052), Expect = 0.0
Identities = 591/591 (100%), Positives = 591/591 (100%)
Query: 1 MCAASASPDNLVFHMKNEMRNIKYKPVDYQQLRALTEAKKLASASAKLKIRKAMLTSKLS 60
MCAASASPDNLVFHMKNEMRNIKYKPVDYQQLRALTEAKKLASASAKLKIRKAMLTSKLS
Sbjct: 1 MCAASASPDNLVFHMKNEMRNIKYKPVDYQQLRALTEAKKLASASAKLKIRKAMLTSKLS 60
Query: 61 KEQTLIKQHKQVWWQEYQRLNEVRCKMESEIKSLLNEENIGNECLCDLTNFEQELSEQQC 120
KEQTLIKQHKQVWWQEYQRLNEVRCKMESEIKSLLNEENIGNECLCDLTNFEQELSEQQC
Sbjct: 61 KEQTLIKQHKQVWWQEYQRLNEVRCKMESEIKSLLNEENIGNECLCDLTNFEQELSEQQC 120
Query: 121 TYLKNVINPIQQLRADLKYRQHHTLQHSHPHIEFNSMKVLEEVDFVKKQLKTVFERLRLE 180
TYLKNVINPIQQLRADLKYRQHHTLQHSHPHIEFNSMKVLEEVDFVKKQLKTVFERLRLE
Sbjct: 121 TYLKNVINPIQQLRADLKYRQHHTLQHSHPHIEFNSMKVLEEVDFVKKQLKTVFERLRLE 180
Query: 181 QQRIENDLSDWSIKILDHSLEEKTNPLSELPIELESLECPYPDLKSSILSEFYKFTQKYQ 240
QQRIENDLSDWSIKILDHSLEEKTNPLSELPIELESLECPYPDLKSSILSEFYKFTQKYQ
Sbjct: 181 QQRIENDLSDWSIKILDHSLEEKTNPLSELPIELESLECPYPDLKSSILSEFYKFTQKYQ 240
Query: 241 KKLQDFNLQLEDIYRNCQLSEEDHWIYQAILDQYPGDLFGRRTLYLDMLQRYFPHKSRHD 300
KKLQDFNLQLEDIYRNCQLSEEDHWIYQAILDQYPGDLFGRRTLYLDMLQRYFPHKSRHD
Sbjct: 241 KKLQDFNLQLEDIYRNCQLSEEDHWIYQAILDQYPGDLFGRRTLYLDMLQRYFPHKSRHD 300
Query: 301 LVEHEKYCDQYRFAIEQQNILISNWNKNRKDFIQKAVLTLTEACATHEMESMLAKDKKKQ 360
LVEHEKYCDQYRFAIEQQNILISNWNKNRKDFIQKAVLTLTEACATHEMESMLAKDKKKQ
Sbjct: 301 LVEHEKYCDQYRFAIEQQNILISNWNKNRKDFIQKAVLTLTEACATHEMESMLAKDKKKQ 360
Query: 361 QELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKLWKKKELLQRAEKKKKIKK 420
QELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKLWKKKELLQRAEKKKKIKK
Sbjct: 361 QELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKLWKKKELLQRAEKKKKIKK 420
Query: 421 YWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQELLERRLMEKKEVALQEA 480
YWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQELLERRLMEKKEVALQEA
Sbjct: 421 YWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQELLERRLMEKKEVALQEA 480
Query: 481 HEDKERARRLEALRKQVAVVAQFDPVRMMSDTMASKARMGIEIEEEFILQKPLFTLNTYN 540
HEDKERARRLEALRKQVAVVAQFDPVRMMSDTMASKARMGIEIEEEFILQKPLFTLNTYN
Sbjct: 481 HEDKERARRLEALRKQVAVVAQFDPVRMMSDTMASKARMGIEIEEEFILQKPLFTLNTYN 540
Query: 541 EQQIISDPRLRFELALREAGLHRTLYAKEILPKISPQKPPRKDMESTVFKI 591
EQQIISDPRLRFELALREAGLHRTLYAKEILPKISPQKPPRKDMESTVFKI
Sbjct: 541 EQQIISDPRLRFELALREAGLHRTLYAKEILPKISPQKPPRKDMESTVFKI 591
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 80.1 bits (196), Expect = 5e-15
Identities = 100/498 (20%), Positives = 229/498 (45%), Gaps = 57/498 (11%)
Query: 58 KLSKEQTLIKQHKQVWWQEYQRLNEVRCKMESEIKSLLNEENIGNECLCDLTNFEQELSE 117
+L +++ I++ ++ W++ +RL E KM + + + +E E +L E+EL E
Sbjct: 280 ELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELRE 339
Query: 118 QQCTYLKNVINPIQQLRADLKYRQHHTLQHSHPHIEFNSMKVLEEVDFVKKQLKTVFERL 177
Q+ L+ +Q+ + + + Q ++ + ++ E+ +KQ++ +++
Sbjct: 340 QK--ELREQEEQMQE-QEEKMWEQEEKMREQEEKMWRQEERLWEQ----EKQMREQEQKM 392
Query: 178 RLEQQRIENDLSDWSIKILDHSLEEKTNPLSELPIELESLECPYPDLKSSILSEFYKFTQ 237
R +++R+ W D L EK + E E +E + K + E K T+
Sbjct: 393 RDQEERM------WE---QDERLREKEERMREQEKMWEQVEKMREEKK---MQEQEKKTR 440
Query: 238 KYQKKLQDFNLQLEDIYRNCQLSEEDHWIYQAILDQYPGDLFGRRTLYLDMLQRYFPHKS 297
++K+Q+ ++ + + + EE + + + +++ + + Q+ P +
Sbjct: 441 DQEEKMQE-EERIREREKKMREEEETMREQEEKMQKQEENMWEQEE--KEWQQQRLP-EQ 496
Query: 298 RHDLVEHEKYCDQYRFAIEQQNILISN---WNKNRKDFIQKAVLTLTEACATHE------ 348
+ L E EK +Q EQ+ + W + +K + Q+ + + E
Sbjct: 497 KEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQ 556
Query: 349 ------MESMLAKDKKKQQELCADLKAKVRQ----------WRAHQEEVARLEMEISARR 392
E + K ++Q++ D + K+R+ R +E + E ++ +
Sbjct: 557 EQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQE 616
Query: 393 REKEEEKEKLWKKKELLQRAEKKKKIKKYWAKKKQKW-QEMEMRDLQRLEELK-KLIAEQ 450
+ +E++EK+W+++E +Q E +K W ++++ W QE +M + QRL E K KL +
Sbjct: 617 EKMQEQEEKMWEQEEKMQEQE-----EKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHE 671
Query: 451 SLKDRERVKYRQE-LLERRLMEKKEVALQEAHEDKERARRLEALR-KQVAVVAQFDPVRM 508
++++E+++ ++E + E+ MEKK ++ D+E+ R E++R ++ + + + +R
Sbjct: 672 KMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMRE 731
Query: 509 MSDTMASKARMGIEIEEE 526
+ M + E EEE
Sbjct: 732 QEEKMQEQEEKMQEQEEE 749
Score = 56.2 bits (134), Expect = 8e-08
Identities = 83/376 (22%), Positives = 161/376 (42%), Gaps = 47/376 (12%)
Query: 136 DLKYRQHHTLQHSHPHIEFNSMKVLEEVDFVKKQLKTVFERLRLEQQRIE-----NDLSD 190
DL R HH+ H + L V K+ E L E+ + N +++
Sbjct: 166 DLAGRLHHSW-----HFAGELQRALSAVSTRHKKADRYIEELTKERDALSLELYRNTITN 220
Query: 191 WSIKILDHSLEEKTNPLSELPIELESLECPYPDLKSSILSEFYKFTQKYQKKLQDFNLQL 250
+K + L+EK PL+E E ++ +LK + + Q LQ+ +
Sbjct: 221 EELKKKNAELQEKL-PLAES--EKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQ 277
Query: 251 EDIYRN----CQLSEEDHWIYQAILDQYPGDLFGRRTLYLDMLQRYFPHKSRHDLVEHEK 306
E+ R + EE W + L + G + + ++ + + R L E EK
Sbjct: 278 EEELREQEKKIRKQEEKMWRQEERLREQEGKM-------REQEEKMWRQEKR--LREQEK 328
Query: 307 YCDQYRFAIEQQNILISNWNKNRKDFIQKAVLTLTEACATHEMESMLAKDKK--KQQELC 364
+ + +Q L + +++ +Q+ + E + E M +++K +Q+E
Sbjct: 329 ELREQEKELREQKEL-----REQEEQMQEQEEKMWE-----QEEKMREQEEKMWRQEERL 378
Query: 365 ADLKAKVRQWRAHQEEVARLEMEISARRREKEE---EKEKLWKKKELLQRAEKKKKIKKY 421
+ + ++R+ + E R REKEE E+EK+W++ E ++ +K ++
Sbjct: 379 WEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQE---- 434
Query: 422 WAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQELLERRL-MEKKEVALQEA 480
+KK + QE +M++ +R+ E +K + E+ RE+ + Q+ E E+KE Q
Sbjct: 435 -QEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRL 493
Query: 481 HEDKERARRLEALRKQ 496
E KE+ E +++Q
Sbjct: 494 PEQKEKLWEQEKMQEQ 509
Score = 55.5 bits (132), Expect = 1e-07
Identities = 96/526 (18%), Positives = 227/526 (43%), Gaps = 43/526 (8%)
Query: 12 VFHMKNEMRNIKYKPVDYQQLRALTEAKKLASASAKLKIRKAML--TSKLSKEQTLIKQH 69
++ + +MR + K D Q+ R + ++L +++ ++ M K+ +E+ + +Q
Sbjct: 378 LWEQEKQMREQEQKMRD-QEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQE 436
Query: 70 KQVWWQEYQRLNEVRCKMESEIKSLLNEENIGNECLCDLTNFEQELSEQQCTYLKNVINP 129
K+ QE + E R + K + EE E + E+ + EQ+ + P
Sbjct: 437 KKTRDQEEKMQEEERIRERE--KKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLP 494
Query: 130 IQQLRADLKYRQHHTLQHSHPHIEFNSMKVLEEVDFVKKQLKTVFERLRLEQQ----RIE 185
Q+ K + +Q I K+ ++ + ++ K + EQ+ E
Sbjct: 495 EQKE----KLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQE 550
Query: 186 NDLSDWSIKILDHS--LEEKTNPLSELPIELESLECPYPDLKSSILSEFYKFTQKYQKKL 243
+ D K+ D +E+KT + + E + + E K ++ ++ +
Sbjct: 551 EKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKM-----REEERMREREKKMREEEEMM 605
Query: 244 QDFNLQLEDIYRNCQLSEEDHWIYQAILDQYPGDLFGRRTLYLDMLQRYFPHK----SRH 299
++ ++++ Q EE W + + + ++ + + ++ + + +
Sbjct: 606 REQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKE 665
Query: 300 DLVEHEKYCDQYRFAIEQQNILISNWNKNRKDF-IQKAVLTLTEACATHEMESMLAKDKK 358
L EHEK +Q + +++ I W + + + Q+ + E ESM ++KK
Sbjct: 666 KLWEHEKMQEQEKMQEQEEKI----WEQEKMEKKTQEQEKKTWDQEKMREEESMREREKK 721
Query: 359 --KQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKLWKKKELLQRAEKKK 416
+++E+ + + K+++ +E++ E E+ + + E++EK+W+++ L ++ EK
Sbjct: 722 MREEEEMMREQEEKMQE---QEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLW 778
Query: 417 KIKKYWAKKKQKWQEMEMRDLQ---RLEELKKLIAEQSLKDRERVKYRQEL----LERRL 469
+ +K ++K QE +MRD + R +E K E+ ++ +E + QE E ++
Sbjct: 779 EHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKM 838
Query: 470 --MEKKEVALQEAHEDKERARRLEALRKQVAVVAQFDPVRMMSDTM 513
E+K +E E+K + + + ++ + Q + +R + M
Sbjct: 839 WGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKM 884
Score = 52.4 bits (124), Expect = 1e-06
Identities = 78/333 (23%), Positives = 146/333 (43%), Gaps = 68/333 (20%)
Query: 217 LECPYPDLKSSILSEFYKFTQKYQKKLQD--------FNLQLEDIYRNCQLSEEDHWIYQ 268
L C +L++++ ++Q +K +D FNL L +R L +
Sbjct: 107 LTCQKTELETALY-----YSQDAARKFEDGNLGTPSSFNLALSQAFRGSPLG----CVST 157
Query: 269 AILDQYPGDLFGR---RTLYLDMLQRYFP-----HKSRHDLVEHEKYCDQYRFAIEQQNI 320
+++ DL GR + LQR HK +E E ++ ++E
Sbjct: 158 SLIPGESKDLAGRLHHSWHFAGELQRALSAVSTRHKKADRYIE-ELTKERDALSLELYRN 216
Query: 321 LISNWNKNRKDFIQKAVLTLTEACATHEMESML-AKDKKKQQELCADLKAKVRQWRAHQE 379
I+N +K+ + L L E+ + E L K+ K++ E L +V Q QE
Sbjct: 217 TITNEELKKKNAELQEKLPLAES---EKSEIQLNVKELKRKLERAKFLLPQV-QTNTLQE 272
Query: 380 EVARLEMEISARRREKEEEKEKLWKKKELLQRAEKK--KKIKKYWAKKKQ--------KW 429
E+ R E E+ + ++ +++EK+W+++E L+ E K ++ +K W ++K+ +
Sbjct: 273 EMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELRE 332
Query: 430 QEMEMRDLQRLEELKKLIAEQS---------LKDRERVKYRQELLERRLMEKKEVALQEA 480
QE E+R+ + L E ++ + EQ ++++E +RQE ER ++K++ QE
Sbjct: 333 QEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQE--ERLWEQEKQMREQEQ 390
Query: 481 ----------------HEDKERARRLEALRKQV 497
E +ER R E + +QV
Sbjct: 391 KMRDQEERMWEQDERLREKEERMREQEKMWEQV 423
Score = 47.8 bits (112), Expect = 3e-05
Identities = 89/447 (19%), Positives = 187/447 (41%), Gaps = 55/447 (12%)
Query: 30 QQLRALTEAKKLASASAKLKIRKAMLTSKLSKEQTLIKQHKQVWWQEYQRLNEVRCKMES 89
+Q L E +K+ K+ ++ K+ ++ + Q K++W QE R E + E
Sbjct: 495 EQKEKLWEQEKMQEQEEKIWEQE----EKIRDQEEMWGQEKKMWRQEKMREQEDQM-WEQ 549
Query: 90 EIKSLLNEENIGNECLCDLTNFEQELSEQQCTYLKNVINPIQQLRADLKYRQHHT-LQHS 148
E K E+ + ++ E++ EQ+ K + +++R + + R+ ++
Sbjct: 550 EEKMRDQEQKMWDQ----EERMEKKTQEQE----KKTWDQEEKMREEERMREREKKMREE 601
Query: 149 HPHIEFNSMKVLEEVDFVKKQLKTVFERLRLEQQRIENDLSDWSIKILDHSLEEKTNPLS 208
+ K+ E+ + +++Q + ++E+ E++ E + W + EEK
Sbjct: 602 EEMMREQEEKMQEQEEKMQEQEEKMWEQ---EEKMQEQEEKMWEQEEKMWEQEEKMWEQQ 658
Query: 209 ELPIELESLECPYPDLKSSILSEFYKFTQKYQKKLQDFNL-QLEDIYRNCQLSEEDHWIY 267
LP + E L E K ++ + + Q+ + + E + + Q E+ W
Sbjct: 659 RLPEQKEKLW------------EHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQ 706
Query: 268 QAILDQYPGDLFGRRTLYLDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNILISNWNK 327
+ + ++ ++ + + R K + + EK +Q EQ+ + W +
Sbjct: 707 EKMREEESMREREKKMREEEEMMREQEEKMQE---QEEKMQEQEEEMWEQEEKM---WEQ 760
Query: 328 NRKDFIQKAVLTLTEACATHEMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEME 387
K + Q+ + E HE K ++QE + + K+R QEE R + E
Sbjct: 761 EEKMWEQQRLPEQKEKLWEHE--------KMQEQEKIWEQEEKMRD----QEEKMRGQEE 808
Query: 388 ISARRREKEE-EKEKLWKKKELLQRAEKKKKIKKYWAKKKQKW-QEMEMRDLQRLEELKK 445
+ EK ++EK+W ++E + E+K W ++++ W QE +M + + +E K
Sbjct: 809 KMRGQEEKMRGQEEKMWGQEEKMWGQEEKM-----WGQEEKMWGQEEKMEEKMQGQEEKM 863
Query: 446 LIAEQSLKDRERVKYRQELLERRLMEK 472
E+ ++ +E QE R EK
Sbjct: 864 REQEEKMRGQEEKMREQEEKMRGQEEK 890
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 69.7 bits (169), Expect = 7e-12
Identities = 86/388 (22%), Positives = 173/388 (44%), Gaps = 32/388 (8%)
Query: 158 KVLEEVDFVKKQLKTVFERLRLEQQRIENDLSDWSIKILDHSLEEKTNPLSE----LPIE 213
+ L V KK+ E L E+ + +L + I D L+EK L E + E
Sbjct: 167 QALSAVATQKKKADRYIEELTKERDALSLEL--YRNTITDEELKEKNAKLQEKLQLVESE 224
Query: 214 LESLECPYPDLKSSI-LSEFYKFTQKYQKKLQDFNLQLEDIYRNCQLSEEDHWIYQAILD 272
++ +LK + ++ Q+ Q + +L+ + Q E++ ++ +
Sbjct: 225 KSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQ 284
Query: 273 QYPGDLFGRRTLYLDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNILISNWNKNRKDF 332
Q ++ + + + + EK +Q Q+ ++ W K K
Sbjct: 285 QQEEKMWRQ--------EEKIQEREEKIQEQEEKIREQEEKMRRQEEMM---WEKEEKMR 333
Query: 333 IQKAVLTLTEACATHEMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEISARR 392
Q+ ++ E E M ++K ++QE + K+R+ QE+ A++ R+
Sbjct: 334 RQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM-----WRQ 388
Query: 393 REK-EEEKEKLWKKKELLQRAEKK--KKIKKYWAKKK--QKWQEMEMRDLQRLEELKKLI 447
EK E++EK+ +++E++Q E+K ++ +K W +++ Q+ +E R +++ E +K I
Sbjct: 389 EEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKI 448
Query: 448 AEQSLKDRERVKYRQELLERRLMEKKEVALQEA--HEDKERARRL-EALRKQVAVV-AQF 503
EQ K RE+ + QE E+ ++ ++ QEA E +E+ RR E +R+Q + Q
Sbjct: 449 REQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQE 508
Query: 504 DPVRMMSDTMASKARMGIEIEEEFILQK 531
+ +R + M + E EE+ Q+
Sbjct: 509 EKIREQEEMMQEQEEKMWEQEEKMCEQE 536
Score = 60.8 bits (146), Expect = 3e-09
Identities = 70/350 (20%), Positives = 161/350 (46%), Gaps = 30/350 (8%)
Query: 162 EVDFVKKQLKTVFER--LRLEQQRIENDLSDWSIKILDHSLEEKTNPLSELPIELESLEC 219
E+ K+LK ER L L QQ+++ + DH +E + ++L ++E E
Sbjct: 227 EIQLNVKELKRKLERAKLLLPQQQLQAEA--------DHLGKELQSVSAKLQAQVEENEL 278
Query: 220 PYPDLKSSILSEFYKFTQKYQK---KLQDFNLQLEDIYRNCQLSEEDHWIYQAILDQYPG 276
+ L + ++ +K Q+ K+Q+ ++ + + EE W + + +
Sbjct: 279 -WNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEE 337
Query: 277 DLFGRRTLYLDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNILISNWNKNRKDFIQKA 336
++ + ++ ++ + + E + ++ R ++Q W + K Q+
Sbjct: 338 MMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE 397
Query: 337 VLTLTEACATHEMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKE 396
+ E E M+ + ++K E + + + + +E++ R E +I + ++
Sbjct: 398 KI--------REQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIR 449
Query: 397 EEKEKLWKKKELLQRAEKKK-----KIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQS 451
E++EK+ +++E++Q E+K K+ + AK +++ ++M R +++ E +K I EQ
Sbjct: 450 EQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMR-RQEEKIREQEKKIREQE 508
Query: 452 LKDRERVKYRQELLERRLMEKKEVALQE--AHEDKERARRLEALRKQVAV 499
K RE+ + QE E+ +++++ QE E +E+ RR E ++ V
Sbjct: 509 EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEV 558
Score = 49.3 bits (116), Expect = 1e-05
Identities = 67/409 (16%), Positives = 187/409 (45%), Gaps = 46/409 (11%)
Query: 39 KKLASASAKLKIRKAMLTSKLSKEQTLIKQHKQVWWQEYQRLNEVRCKMESEIKSLLNEE 98
++L +AKL+ + ++ S+ S+ Q +K+ K+ + L + + + E++
Sbjct: 205 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEAD-------- 256
Query: 99 NIGNECLCDLTNFEQELSEQQCTYLKNVINPIQQLRADLKYRQHHTLQHSHPHIEFNSMK 158
++G E + ++ E + + N + Q + + +RQ +Q I+ K
Sbjct: 257 HLGKELQSVSAKLQAQVEENE------LWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEK 310
Query: 159 VLEEVDFVKKQLKTVFERLRLEQQRIENDLSDWSIKILDHSLEEKTNPLSELPIELESLE 218
+ E+ + +++Q + ++E+ E+ R + ++ W + LEEK + ++ + E +
Sbjct: 311 IREQEEKMRRQEEMMWEKE--EKMRRQEEMM-WEKEEKIRELEEKMHEQEKIREQEEKRQ 367
Query: 219 CPYPDLKSSILSEFYKFTQKYQKKLQDFNLQLEDIYRNCQLSEEDHWIY-QAILDQYPGD 277
E K ++ +++ Q+ + ++ ++ E++ I Q + Q +
Sbjct: 368 ------------EEEKIREQEKRQEQEAKMWRQEE----KIREQEEKIREQEEMMQEQEE 411
Query: 278 LFGRRTLYLDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNILISNWNKNRKDFIQKAV 337
G + + + + + EK +Q + EQ+ + + +++ +Q+
Sbjct: 412 KMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKI-----REQEEMMQEQE 466
Query: 338 LTLTEACATHEMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEE 397
+ E E + + + K QE ++ + + R ++++ E +I + +E
Sbjct: 467 EKMGE------QEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE 520
Query: 398 EKEKLWKKKE-LLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKK 445
++EK+W+++E + ++ EK ++ ++ ++++K +E E+R Q+ E++++
Sbjct: 521 QEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 68.2 bits (165), Expect = 2e-11
Identities = 81/402 (20%), Positives = 180/402 (44%), Gaps = 63/402 (15%)
Query: 112 EQELSEQQCTYLKNVINPIQQLR---ADLKYRQHHTLQHSHPHIEFNSMKVLEEVDFVKK 168
+++++E+ T+ K V+ LR + R ++L H + + +++K
Sbjct: 139 QEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDH----AVRMGTYIEK 194
Query: 169 QLKTVFERLRLEQQRIENDLSDWSIKILDHSLEEKTNPLSELPIELESLECPYPDLKSSI 228
K ER L + N ++D +K + L+EK L + E ++ DLK +
Sbjct: 195 LTK---ERDALSLELYRNTITDEELKEKNAELQEK---LRLVESEKSEIQLNVKDLKRKL 248
Query: 229 -LSEFYKFTQKYQKKLQDFNLQLEDIYRNCQLSEEDHWIYQAILDQYPGDLFGRRTLYLD 287
++ Q+ Q + +L+ + Q E++ ++ + Q ++ + +
Sbjct: 249 ERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQE----E 304
Query: 288 MLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNILISNWNKNRKDFIQKAVLTLTEACATH 347
+Q + EK C+Q EQ+ + W + K H
Sbjct: 305 KIQE-----------QEEKMCEQELKIREQEEKM---WRQEEK---------------MH 335
Query: 348 EMESMLAKDKKK---QQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKLWK 404
E E + + + K Q+E + + K+R+ +E++ R E +I + + +E++E++W+
Sbjct: 336 EQEEKIREQEDKMWRQEEKIREQEEKIRE---QEEKMWRQEEKIREQDEKIQEQEEEMWR 392
Query: 405 KKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDL--------QRLEELKKLIAEQSLKDRE 456
++E ++ E+K++ K + +KK + Q+ ++R+ +++ EL++++ +Q K RE
Sbjct: 393 QEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLRE 452
Query: 457 RVKYRQELLERRLMEKKEVALQE--AHEDKERARRLEALRKQ 496
+ QE E+ +++++ QE E +E+ R E L KQ
Sbjct: 453 VEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQ 494
Score = 54.7 bits (130), Expect = 2e-07
Identities = 36/136 (26%), Positives = 80/136 (58%), Gaps = 15/136 (11%)
Query: 348 EMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKLWKKKE 407
E+E M+ ++K +E+ ++ + + + +E++ R E +I +E++EK W++++
Sbjct: 438 ELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKI-------QEQEEKTWRQEK 490
Query: 408 LLQRAEK-KKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQELLE 466
LL++ EK ++ +K W ++++ W++ E +Q EE K E+ ++++E ++QE
Sbjct: 491 LLKQEEKIWEQEEKMWRQEEKMWEQEE--KMQEQEE-KMQRQEEKMREQEVRLWQQE--- 544
Query: 467 RRLMEKKEVALQEAHE 482
M+++EV LQE E
Sbjct: 545 -EKMQEQEVRLQELEE 559
Score = 52.4 bits (124), Expect = 1e-06
Identities = 45/189 (23%), Positives = 102/189 (53%), Gaps = 17/189 (8%)
Query: 350 ESMLAKDKK--KQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKLWKKKE 407
E M +++K +Q+E + + K+R+ +E++ R E ++ + + E+++K+W+++E
Sbjct: 297 EKMWRQEEKIQEQEEKMCEQELKIRE---QEEKMWRQEEKMHEQEEKIREQEDKMWRQEE 353
Query: 408 LLQRAEKK--KKIKKYWAKKKQKWQEMEMRDLQRLEEL---KKLIAEQSLKDRERVKYRQ 462
++ E+K ++ +K W ++++K +E + + ++ EE+ ++ I EQ K +E++ +RQ
Sbjct: 354 KIREQEEKIREQEEKMW-RQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKM-WRQ 411
Query: 463 ELLERRLMEKKEVALQEAHEDKERARRLEALRKQVAVVAQFDPVRMMSDTMASKARMGIE 522
E R EK +E +E+ R LE + + Q + +R + + M + E
Sbjct: 412 EKKMREQDEKIREQEEEMWRQEEKIRELEEMMQD-----QEEKLREVEEKMQEEEEKMQE 466
Query: 523 IEEEFILQK 531
EE+ Q+
Sbjct: 467 QEEKIQRQE 475
Score = 39.3 bits (90), Expect = 0.010
Identities = 90/477 (18%), Positives = 181/477 (37%), Gaps = 103/477 (21%)
Query: 26 PVDYQQLRALTEAKKLASASAKLKIRKAMLTSKLSKEQTLIKQHKQVWWQEYQRLNEVRC 85
P Q+ A K+L S SAKL+ + + L +Q ++ W++ +++ E
Sbjct: 256 PQQQLQVEADRLGKELQSVSAKLQAQ----VEENELWNLLNQQQEEKMWRQEEKIQEQEE 311
Query: 86 KM-ESEIKSLLNEENIGNECLCDLTNFEQELSEQQCTYLKNVINPIQQLRADLKYRQHHT 144
KM E E+K EE + + E+++ EQ+ I++ + D +RQ
Sbjct: 312 KMCEQELKIREQEEKMWRQ--------EEKMHEQE--------EKIRE-QEDKMWRQEEK 354
Query: 145 LQHSHPHIEFNSMKVLEEVDFVKKQLKTVFE----------RLRLEQQRIENDL--SDWS 192
++ I K+ + + +++Q + + E ++R ++++ + + +
Sbjct: 355 IREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKK 414
Query: 193 IKILDHSLEEKTNPLSELPIELESLECPYPDLKSSILSEFYKFTQKYQKKLQDFNLQLED 252
++ D + E+ + ++ LE D + L E + Q+ ++K+Q+ +++
Sbjct: 415 MREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEK-LREVEEKMQEEEEKMQEQEEKIQR 473
Query: 253 IYRNCQLSEEDHWIYQAILDQYPGDLFGRRTLYLDMLQRYFPHKSRHDLVEHEKYCDQYR 312
Q EE W + +L Q EK +Q
Sbjct: 474 QEEKIQEQEEKTWRQEKLLKQ------------------------------EEKIWEQEE 503
Query: 313 FAIEQQNILISNWNKNRKDFIQKAVLTLTEACATHEMESMLAKDKKKQQELCADLKAKVR 372
Q+ + W + K E E + + ++K +E +VR
Sbjct: 504 KMWRQEEKM---WEQEEK---------------MQEQEEKMQRQEEKMRE------QEVR 539
Query: 373 QWRAHQEEVARLEMEISARRREKEEEKEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEM 432
W Q+E E E+ R +E EE KL +K ELL A ++ ++ E+
Sbjct: 540 LW---QQEEKMQEQEV--RLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVEL 594
Query: 433 EMRDLQRLEELKKLIAEQSLKDRERVKYRQELLERRLMEKKEVALQEAHEDKERARR 489
+ ++ Q L Q +D R +Q + + + + AL K RA+R
Sbjct: 595 KSQEAQSL---------QQQQDHYRGHLQQYVAAYQQLASGKEALPSCSSRKLRAKR 642
>gi|94680976 coiled-coil domain containing 112 isoform 1 [Homo
sapiens]
Length = 529
Score = 68.2 bits (165), Expect = 2e-11
Identities = 92/426 (21%), Positives = 189/426 (44%), Gaps = 48/426 (11%)
Query: 108 LTNFEQELSEQQCTYLKNVINPIQQLRADLKYRQHHTLQHSHPHIEF--NSMKVLEEVDF 165
L E +L + T + + ++ ++K QH L+ P +F +++EE++
Sbjct: 106 LEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQ-LKDVKPTPDFVEKLREMMEEIEN 164
Query: 166 V----KKQLKTVFERLRLEQQRIENDLSDWSIKILDHSLEEKTNPLSELPIELESLECPY 221
K++ + ++E L E++ N+LS S KI +L N +E S + P
Sbjct: 165 AINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALG---NSETEKAFRAISSKVPV 221
Query: 222 PDLKSSILSEFYKFTQKYQKKLQDFNLQLEDIY-RNCQLSEEDHWIYQAILDQYPGDLFG 280
+ S L E ++ DF L+ R + DH + + +++ G
Sbjct: 222 DKVTPSTLPE----------EVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHKG---- 267
Query: 281 RRTLYLDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNILISNWNKNRKDFIQKAVLTL 340
+ +++ + + P K++ ++ +HEK+ ++ E++ I W K +K ++ + L
Sbjct: 268 -KPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIW-KTKKQQKREEIFKL 325
Query: 341 TEACATHEM--ESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEE 398
E + + ++K+++E K V W+ + +EM + + KEEE
Sbjct: 326 KEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKS----IEMSMKCASQLKEEE 381
Query: 399 KEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERV 458
+++ +KE ++ + K ++ Y +KK E + RLE K I E++ K +R
Sbjct: 382 EKEKKHQKERQRQFKLKLLLESYTQQKK------EQEEFLRLE---KEIREKAEKAEKRK 432
Query: 459 KYRQEL--LERRLMEKKEVAL--QEAHEDK--ERARRLEALRKQVAVVAQFDPVRMMSDT 512
E+ + R + K E+ + ++A ED+ ++ RRL L+++V DP R+ T
Sbjct: 433 NAADEISRFQERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVENNVSRDPSRLYKPT 492
Query: 513 MASKAR 518
+ R
Sbjct: 493 KGWEER 498
Score = 32.7 bits (73), Expect = 0.96
Identities = 32/167 (19%), Positives = 70/167 (41%), Gaps = 25/167 (14%)
Query: 392 RREKEEEKEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQS 451
+ + E ++ + W +K L KK+ I+ + KK+QK +E+
Sbjct: 282 KTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEI------------------- 322
Query: 452 LKDRERVKYRQELLERRLMEKKEVALQEAHEDKERARRLEALRKQVAVVAQFDPVRMMSD 511
K +E+ L + + ++ Q+ + K++ +EA +KQ ++ + +
Sbjct: 323 FKLKEKADNTPVLFHNKQEDNQK---QKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKE 379
Query: 512 TMASKARMGIEIEEEFILQKPLFTLNTYNEQQIISDPRLRFELALRE 558
+ + E + +F L+ L +Y +Q+ + LR E +RE
Sbjct: 380 EEEKEKKHQKERQRQFKLK---LLLESYTQQKKEQEEFLRLEKEIRE 423
>gi|145580595 coiled-coil domain containing 112 isoform 2 [Homo
sapiens]
Length = 446
Score = 68.2 bits (165), Expect = 2e-11
Identities = 92/426 (21%), Positives = 189/426 (44%), Gaps = 48/426 (11%)
Query: 108 LTNFEQELSEQQCTYLKNVINPIQQLRADLKYRQHHTLQHSHPHIEF--NSMKVLEEVDF 165
L E +L + T + + ++ ++K QH L+ P +F +++EE++
Sbjct: 23 LEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQ-LKDVKPTPDFVEKLREMMEEIEN 81
Query: 166 V----KKQLKTVFERLRLEQQRIENDLSDWSIKILDHSLEEKTNPLSELPIELESLECPY 221
K++ + ++E L E++ N+LS S KI +L N +E S + P
Sbjct: 82 AINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALG---NSETEKAFRAISSKVPV 138
Query: 222 PDLKSSILSEFYKFTQKYQKKLQDFNLQLEDIY-RNCQLSEEDHWIYQAILDQYPGDLFG 280
+ S L E ++ DF L+ R + DH + + +++ G
Sbjct: 139 DKVTPSTLPE----------EVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHKG---- 184
Query: 281 RRTLYLDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNILISNWNKNRKDFIQKAVLTL 340
+ +++ + + P K++ ++ +HEK+ ++ E++ I W K +K ++ + L
Sbjct: 185 -KPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIW-KTKKQQKREEIFKL 242
Query: 341 TEACATHEM--ESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEE 398
E + + ++K+++E K V W+ + +EM + + KEEE
Sbjct: 243 KEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKS----IEMSMKCASQLKEEE 298
Query: 399 KEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERV 458
+++ +KE ++ + K ++ Y +KK E + RLE K I E++ K +R
Sbjct: 299 EKEKKHQKERQRQFKLKLLLESYTQQKK------EQEEFLRLE---KEIREKAEKAEKRK 349
Query: 459 KYRQEL--LERRLMEKKEVAL--QEAHEDK--ERARRLEALRKQVAVVAQFDPVRMMSDT 512
E+ + R + K E+ + ++A ED+ ++ RRL L+++V DP R+ T
Sbjct: 350 NAADEISRFQERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVENNVSRDPSRLYKPT 409
Query: 513 MASKAR 518
+ R
Sbjct: 410 KGWEER 415
Score = 32.7 bits (73), Expect = 0.96
Identities = 32/167 (19%), Positives = 70/167 (41%), Gaps = 25/167 (14%)
Query: 392 RREKEEEKEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQS 451
+ + E ++ + W +K L KK+ I+ + KK+QK +E+
Sbjct: 199 KTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEI------------------- 239
Query: 452 LKDRERVKYRQELLERRLMEKKEVALQEAHEDKERARRLEALRKQVAVVAQFDPVRMMSD 511
K +E+ L + + ++ Q+ + K++ +EA +KQ ++ + +
Sbjct: 240 FKLKEKADNTPVLFHNKQEDNQK---QKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKE 296
Query: 512 TMASKARMGIEIEEEFILQKPLFTLNTYNEQQIISDPRLRFELALRE 558
+ + E + +F L+ L +Y +Q+ + LR E +RE
Sbjct: 297 EEEKEKKHQKERQRQFKLK---LLLESYTQQKKEQEEFLRLEKEIRE 340
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 66.2 bits (160), Expect = 8e-11
Identities = 70/337 (20%), Positives = 152/337 (45%), Gaps = 54/337 (16%)
Query: 178 RLEQQRIENDLSDWSIKILDHSLEEKTNPLSE----LPIELESLECPYPDLKSSI-LSEF 232
+L ++R L + I D L+EK L E + E ++ DLK + ++
Sbjct: 194 KLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQL 253
Query: 233 YKFTQKYQKKLQDFNLQLEDIYRNCQLSEEDHWIYQAILDQYPGDLFGRRTLYLDMLQRY 292
Q+ Q + +L+ + Q E++ ++ + Q ++ + + +Q
Sbjct: 254 LLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQE----EKIQE- 308
Query: 293 FPHKSRHDLVEHEKYCDQYRFAIEQQNILISNWNKNRKDFIQKAVLTLTEACATHEMESM 352
+ EK C+Q EQ+ + W + K HE E
Sbjct: 309 ----------QEEKMCEQELKIREQEEKM---WRQEEK---------------MHEQEEK 340
Query: 353 LAKDKKK---QQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKLWKKKELL 409
+ + + K Q+E + + K+R+ +E++ R E +I + + +E++E++W+++E +
Sbjct: 341 IREQEDKMWRQEEKIREQEEKIRE---QEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKI 397
Query: 410 QRAEKKKKIKKYWAKKKQKWQEMEMRDL--------QRLEELKKLIAEQSLKDRERVKYR 461
+ E+K++ K + +KK + Q+ ++R+ +++ EL++++ +Q K RE +
Sbjct: 398 REQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKM 457
Query: 462 QELLERRLMEKKEVALQE--AHEDKERARRLEALRKQ 496
QE E+ +++++ QE E +E+ R E L KQ
Sbjct: 458 QEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQ 494
Score = 54.7 bits (130), Expect = 2e-07
Identities = 36/136 (26%), Positives = 80/136 (58%), Gaps = 15/136 (11%)
Query: 348 EMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKLWKKKE 407
E+E M+ ++K +E+ ++ + + + +E++ R E +I +E++EK W++++
Sbjct: 438 ELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKI-------QEQEEKTWRQEK 490
Query: 408 LLQRAEK-KKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQELLE 466
LL++ EK ++ +K W ++++ W++ E +Q EE K E+ ++++E ++QE
Sbjct: 491 LLKQEEKIWEQEEKMWRQEEKMWEQEE--KMQEQEE-KMQRQEEKMREQEVRLWQQE--- 544
Query: 467 RRLMEKKEVALQEAHE 482
M+++EV LQE E
Sbjct: 545 -EKMQEQEVRLQELEE 559
Score = 52.4 bits (124), Expect = 1e-06
Identities = 45/189 (23%), Positives = 102/189 (53%), Gaps = 17/189 (8%)
Query: 350 ESMLAKDKK--KQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKLWKKKE 407
E M +++K +Q+E + + K+R+ +E++ R E ++ + + E+++K+W+++E
Sbjct: 297 EKMWRQEEKIQEQEEKMCEQELKIRE---QEEKMWRQEEKMHEQEEKIREQEDKMWRQEE 353
Query: 408 LLQRAEKK--KKIKKYWAKKKQKWQEMEMRDLQRLEEL---KKLIAEQSLKDRERVKYRQ 462
++ E+K ++ +K W ++++K +E + + ++ EE+ ++ I EQ K +E++ +RQ
Sbjct: 354 KIREQEEKIREQEEKMW-RQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKM-WRQ 411
Query: 463 ELLERRLMEKKEVALQEAHEDKERARRLEALRKQVAVVAQFDPVRMMSDTMASKARMGIE 522
E R EK +E +E+ R LE + + Q + +R + + M + E
Sbjct: 412 EKKMREQDEKIREQEEEMWRQEEKIRELEEMMQD-----QEEKLREVEEKMQEEEEKMQE 466
Query: 523 IEEEFILQK 531
EE+ Q+
Sbjct: 467 QEEKIQRQE 475
Score = 45.8 bits (107), Expect = 1e-04
Identities = 56/224 (25%), Positives = 107/224 (47%), Gaps = 32/224 (14%)
Query: 303 EHEKYCDQYRFAIEQQNILISNWNKNRKDFIQKAVLTLTEACATHEMESMLAKDKKKQQE 362
+ EK +Q EQ+ + W + K Q + E + E + +++K+Q++
Sbjct: 351 QEEKIREQEEKIREQEEKM---WRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEK 407
Query: 363 LCADLKAKVRQW----RAHQEEVARLEMEI----------SARRREKE----EEKEKLWK 404
+ K K+R+ R +EE+ R E +I + RE E EE+EK+ +
Sbjct: 408 MWRQEK-KMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQE 466
Query: 405 KKELLQRAEKK--KKIKKYWAKKKQKWQE---MEMRDLQRLEELKKLIAEQSLKDRERVK 459
++E +QR E+K ++ +K W ++K QE E + +E K E+ ++++E
Sbjct: 467 QEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKM 526
Query: 460 YRQELLERRLMEKKEVAL-QEAHEDKERARRLEALRKQVAVVAQ 502
RQE M ++EV L Q+ + +E+ RL+ L +++ + Q
Sbjct: 527 QRQE----EKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQ 566
Score = 39.3 bits (90), Expect = 0.010
Identities = 90/477 (18%), Positives = 181/477 (37%), Gaps = 103/477 (21%)
Query: 26 PVDYQQLRALTEAKKLASASAKLKIRKAMLTSKLSKEQTLIKQHKQVWWQEYQRLNEVRC 85
P Q+ A K+L S SAKL+ + + L +Q ++ W++ +++ E
Sbjct: 256 PQQQLQVEADRLGKELQSVSAKLQAQ----VEENELWNLLNQQQEEKMWRQEEKIQEQEE 311
Query: 86 KM-ESEIKSLLNEENIGNECLCDLTNFEQELSEQQCTYLKNVINPIQQLRADLKYRQHHT 144
KM E E+K EE + + E+++ EQ+ I++ + D +RQ
Sbjct: 312 KMCEQELKIREQEEKMWRQ--------EEKMHEQE--------EKIRE-QEDKMWRQEEK 354
Query: 145 LQHSHPHIEFNSMKVLEEVDFVKKQLKTVFE----------RLRLEQQRIENDL--SDWS 192
++ I K+ + + +++Q + + E ++R ++++ + + +
Sbjct: 355 IREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKK 414
Query: 193 IKILDHSLEEKTNPLSELPIELESLECPYPDLKSSILSEFYKFTQKYQKKLQDFNLQLED 252
++ D + E+ + ++ LE D + L E + Q+ ++K+Q+ +++
Sbjct: 415 MREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEK-LREVEEKMQEEEEKMQEQEEKIQR 473
Query: 253 IYRNCQLSEEDHWIYQAILDQYPGDLFGRRTLYLDMLQRYFPHKSRHDLVEHEKYCDQYR 312
Q EE W + +L Q EK +Q
Sbjct: 474 QEEKIQEQEEKTWRQEKLLKQ------------------------------EEKIWEQEE 503
Query: 313 FAIEQQNILISNWNKNRKDFIQKAVLTLTEACATHEMESMLAKDKKKQQELCADLKAKVR 372
Q+ + W + K E E + + ++K +E +VR
Sbjct: 504 KMWRQEEKM---WEQEEK---------------MQEQEEKMQRQEEKMRE------QEVR 539
Query: 373 QWRAHQEEVARLEMEISARRREKEEEKEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEM 432
W Q+E E E+ R +E EE KL +K ELL A ++ ++ E+
Sbjct: 540 LW---QQEEKMQEQEV--RLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVEL 594
Query: 433 EMRDLQRLEELKKLIAEQSLKDRERVKYRQELLERRLMEKKEVALQEAHEDKERARR 489
+ ++ Q L Q +D R +Q + + + + AL K RA+R
Sbjct: 595 KSQEAQSL---------QQQQDHYRGHLQQYVAAYQQLASGKEALPSCSSRKLRAKR 642
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 65.5 bits (158), Expect = 1e-10
Identities = 86/466 (18%), Positives = 206/466 (44%), Gaps = 59/466 (12%)
Query: 58 KLSKEQTLIKQHKQVWWQEYQRLNEVRCKMESEIKSLLNEENIGNECLCDLTNFEQELSE 117
+L +++ I++ ++ W++ +RL E KM + + + +E E +L E+EL E
Sbjct: 242 ELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELRE 301
Query: 118 QQCTYLKNVINPIQQLRADL-------------KYRQHHTLQHSHPHIEFNSMKVLEEVD 164
Q+ L+ +Q+ + +RQ L + K+ ++ +
Sbjct: 302 QK--KLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 359
Query: 165 FVKKQLKTVFERLRLEQQRIENDLSDWSIKILDHSLEEKTNPLSELPIELESLECPYPDL 224
+ +Q ERLR +++R+ W + ++E+ + E ++ E +
Sbjct: 360 RMWEQ----DERLREKEERMREQEKMWE---QEEKMQEEER-IREREKKMREEEETMREQ 411
Query: 225 KSSILSEFYKFTQKYQKKLQDFNL--QLEDIYRNCQLSEEDHWIYQA---ILDQYPGDLF 279
+ + + ++ +K+ Q L Q E ++ ++ E++ I++ I DQ +++
Sbjct: 412 EEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQE--EMW 469
Query: 280 GRRTLYLDMLQRYFPHKSRHDLV--EHEKYCDQYRFAIEQQNILISNWNKNRKDFIQKAV 337
G+ + R + + D + + EK DQ + +Q+ + W ++ + +++
Sbjct: 470 GQEK----KMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERM---WEQDER--LREKE 520
Query: 338 LTLTEACATHEMESMLAKDKKKQQE----------LCADLKAKVRQWRAHQEEVARLEME 387
+ E + E + ++KK Q++ + + + + R+ + +EE E E
Sbjct: 521 ERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE 580
Query: 388 ISARRREKE--EEKEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKK 445
+ +E++ E++EK+W+++E +Q E+K W ++++ W++ E +Q EE+
Sbjct: 581 EKMQEQEEKMREQEEKMWEQEEKMQEQEEKM-----WEQEEKMWEQEEEDKMQEQEEM-M 634
Query: 446 LIAEQSLKDRERVKYRQELLERRLMEKKEVALQEAHEDKERARRLE 491
E+ ++++E + QE R EK ++ +E+ R E
Sbjct: 635 WEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQE 680
Score = 57.8 bits (138), Expect = 3e-08
Identities = 86/469 (18%), Positives = 202/469 (43%), Gaps = 55/469 (11%)
Query: 30 QQLRALTEAKKLASASAKLKIRKAMLTSKLSKEQTLIKQHKQVWWQEYQRLNEVRCKMES 89
Q+ R + K+L +L+ +K KL +++ +++ ++ W++ +++ E KM
Sbjct: 281 QEKRLREQEKELREQEKELREQK-----KLREQEEQMQEQEEKMWEQEEKMREQEEKMWR 335
Query: 90 EIKSLLNEENIGNECLCDLTNFEQELSEQQCTYLKNVINPIQQLRADLKYRQHHTLQHSH 149
+ + L +E E + + E+ + EQ + + +++R K +
Sbjct: 336 QEERLWEQEKQMREQEQKMRDQEERMWEQD----ERLREKEERMREQEKMWEQEEKMQEE 391
Query: 150 PHIEFNSMKVLEEVDFVKKQLKTVFERLRLEQQRIENDLSDWSIKILDHSLEE--KTNPL 207
I K+ EE + +++Q + + ++ E+ E + +W + L E+ + +
Sbjct: 392 ERIREREKKMREEEETMREQEEKMQKQ---EENMWEQEEKEWQQQRLPEQKEKLWEQEKM 448
Query: 208 SELPIELESLECPYPDLKSSILSEFYKFTQKYQKKLQDFNLQLEDIYRNCQLSEEDHWIY 267
E ++ E D + E + Q+ ++ +D + E+ R+ E+ W
Sbjct: 449 QEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRD---QEQKMW-- 503
Query: 268 QAILDQYPGDLFGRRTLYLDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNILISNWNK 327
D +R + R L E E+ + + +Q+ + +
Sbjct: 504 -------------------DQEERMWEQDER--LREKEERMREQKKMWQQEEKM-----R 537
Query: 328 NRKDFIQKAVLTLTEACATHEMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEME 387
K ++ T + E E M ++KK ++E ++ + + QEE R + E
Sbjct: 538 EEKKTQEQEKKTWDQEEKMREEERMREREKKMREE--EEMMREQEEKMQEQEEKMREQEE 595
Query: 388 ISARRREK-EEEKEKLWKKKELLQRAEKKKKIKK----YWAKKKQKWQEMEMRDLQRLEE 442
+ EK +E++EK+W+++E + E++ K+++ W ++++K QE E + ++ E+
Sbjct: 596 KMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMW-EQEEKMQEQEEKMWEQEEK 654
Query: 443 LKKLIAEQSLKDRERVKYRQELLERRLMEKKEVALQEAHEDKERARRLE 491
+++ E+ ++++E QE R EK + ++ E +E+ R E
Sbjct: 655 MRE--QEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQE 701
Score = 53.9 bits (128), Expect = 4e-07
Identities = 35/155 (22%), Positives = 88/155 (56%), Gaps = 15/155 (9%)
Query: 348 EMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKLWKKKE 407
E E + + ++K + L+ + ++ R ++E+ R + ++ + + +E++EK+W+++E
Sbjct: 266 EQEGKMREQEEKMRRQEKRLREQEKELREQEKEL-REQKKLREQEEQMQEQEEKMWEQEE 324
Query: 408 LLQRAEKKKKIKKYWAKKKQKW-QEMEMRDL-QRLEELKKLIAEQSLKDRERVKYRQELL 465
++ E+K W ++++ W QE +MR+ Q++ + ++ + EQ + RE+ + +
Sbjct: 325 KMREQEEKM-----WRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREK---EERMR 376
Query: 466 ERRLMEKKEVALQEAHEDKERARRL----EALRKQ 496
E+ M ++E +QE +ER +++ E +R+Q
Sbjct: 377 EQEKMWEQEEKMQEEERIREREKKMREEEETMREQ 411
Score = 52.8 bits (125), Expect = 9e-07
Identities = 51/193 (26%), Positives = 94/193 (48%), Gaps = 28/193 (14%)
Query: 348 EMESMLAKDKKKQQ-ELCADLKAKVR---QWRAHQEEVARLEMEISARRREKE------- 396
E E M +++K Q+ E + + K+R + QEE + + E + EKE
Sbjct: 377 EQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLP 436
Query: 397 EEKEKLWKKKELLQRAEK----KKKIK---KYWAKKKQKWQEMEMR---DLQRLEELKKL 446
E+KEKLW+++++ ++ EK ++KI+ + W ++K+ W++ +MR D +E K
Sbjct: 437 EQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMR 496
Query: 447 IAEQSLKDRERVKYRQELLERRLMEKKEVALQEAHEDKERARRLEALRKQVAVVAQFDPV 506
EQ + D+E + Q + RL EK+E E K+ ++ E +R++ Q
Sbjct: 497 DQEQKMWDQEERMWEQ---DERLREKEE----RMREQKKMWQQEEKMREEKKTQEQEKKT 549
Query: 507 RMMSDTMASKARM 519
+ M + RM
Sbjct: 550 WDQEEKMREEERM 562
Score = 49.7 bits (117), Expect = 8e-06
Identities = 50/209 (23%), Positives = 105/209 (50%), Gaps = 36/209 (17%)
Query: 311 YRFAIEQQNIL--ISNWNKNRKDFIQKAVLTLTEACATHEMESMLAKDKKKQQELCADLK 368
+ FA E Q L +S W+K +I++ +A + + + ++ K++ A+L+
Sbjct: 137 WHFAGELQRALSAVSTWHKKADRYIEELTKE-RDALSLELYRNTITNEELKKKN--AELQ 193
Query: 369 AKVRQWRAHQEEVARLEMEISARRREKEEEK------------EKLWKKKELLQRAEKK- 415
K+R + + E+ ++ + +R+ E K E++W+++E L+ EKK
Sbjct: 194 EKLRLAESEKSEI---QLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKI 250
Query: 416 -KKIKKYWAKKKQ-KWQEMEMRDLQ--------RLEELKKLIAEQSLKDRERVKYRQELL 465
K+ +K W ++++ + QE +MR+ + RL E +K + EQ + RE+ K R++
Sbjct: 251 RKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQ-- 308
Query: 466 ERRLMEKKEVALQEAH---EDKERARRLE 491
E ++ E++E ++ E +E+ R E
Sbjct: 309 EEQMQEQEEKMWEQEEKMREQEEKMWRQE 337
Score = 48.9 bits (115), Expect = 1e-05
Identities = 76/411 (18%), Positives = 172/411 (41%), Gaps = 36/411 (8%)
Query: 136 DLKYRQHHTLQHSHPHIEFNSMKVLEEVDFVKKQLKTVFERLRLEQQRIENDLSDWSIKI 195
DL R HH+ H + L V K+ E L E+ + +L + I
Sbjct: 128 DLAGRLHHSW-----HFAGELQRALSAVSTWHKKADRYIEELTKERDALSLEL--YRNTI 180
Query: 196 LDHSLEEKTNPLSE----LPIELESLECPYPDLKSSILSEFYKFTQKYQKKLQDFNLQLE 251
+ L++K L E E ++ +LK + + Q LQ+ + E
Sbjct: 181 TNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQE 240
Query: 252 DIYRN----CQLSEEDHWIYQAILDQYPGDLFGRRTLYLDMLQRYFPHKSRHDLVEHEKY 307
+ R + EE W + L + G + + +R + +L E EK
Sbjct: 241 EELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRL--REQEKELREQEKE 298
Query: 308 CDQYRFAIEQQNILISN----WNKNRKDFIQKAVLTLTEACATHEMESMLAKDKK----- 358
+ + EQ+ + W + K Q+ + E + + M +++K
Sbjct: 299 LREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQE 358
Query: 359 ----KQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKE--EEKEKLWKKKELLQRA 412
+Q E + + ++R+ E+ +++ E R REK+ EE+E + +++E +Q+
Sbjct: 359 ERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQ 418
Query: 413 EKK--KKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQS--LKDRERVKYRQELLERR 468
E+ ++ +K W +++ Q+ ++ + ++++E ++ I EQ ++D+E + +++ + R+
Sbjct: 419 EENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQ 478
Query: 469 LMEKKEVALQEAHEDKERARRLEALRKQVAVVAQFDPVRMMSDTMASKARM 519
+++ E+K R + + ++ + Q + +R + M + +M
Sbjct: 479 EKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKM 529
Score = 44.7 bits (104), Expect = 2e-04
Identities = 42/188 (22%), Positives = 88/188 (46%), Gaps = 24/188 (12%)
Query: 303 EHEKYCDQYRFAIEQQNILISNWNKNRKDFIQKAVLTLTEACATHEMESMLAKDKKKQQE 362
+ EK +Q EQ+ + W + K + Q+ E E E M+ + ++K QE
Sbjct: 593 QEEKMWEQEEKMQEQEEKM---WEQEEKMWEQE------EEDKMQEQEEMMWEQEEKMQE 643
Query: 363 LCADLKAKVRQWRAHQEEVARLEMEISARR---REKEE----EKEKLWKKKELLQRAEKK 415
+ + + R +E++ E ++ + RE+EE ++EK+ +++E ++ E+K
Sbjct: 644 QEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEK 703
Query: 416 K--KIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQELLERRLMEKK 473
+ +K W ++++ W + EMR E ++ I +Q K +ER+ +E +
Sbjct: 704 MWGQEEKMWGQEEKMWGQEEMR------EKEERIRDQKEKMQERLPEHEERCSEPCLPPS 757
Query: 474 EVALQEAH 481
+V +H
Sbjct: 758 KVLCNMSH 765
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 65.5 bits (158), Expect = 1e-10
Identities = 51/232 (21%), Positives = 103/232 (44%), Gaps = 38/232 (16%)
Query: 287 DMLQRYFPHKSRHDLVEHEKYC-DQYRFAIEQQNILISNWNKNRKDFIQKAVLTLTEACA 345
+ L R P K R E E+ C ++ E++ +L K R+ +++ E
Sbjct: 1091 EQLLREEPEKRRRQ--ERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQ 1148
Query: 346 THEMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKLWKK 405
E +K+++QEL RQ+R +E E + + ++ +E+E+ +++
Sbjct: 1149 EEEQLLREEPEKRRRQEL-------ERQYREEEELQQEEEQLLREEQEKRRQERERQYRE 1201
Query: 406 KELLQRAEKKKKIKKYWAKKKQKWQ----------------------------EMEMRDL 437
+E LQR ++K++ + + KWQ + ++RD
Sbjct: 1202 EEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDR 1261
Query: 438 QRLEELKKLIAEQSLKDRERVKYRQELLERRLMEKKEVALQEAHEDKERARR 489
Q ++L+ L+ EQ +DRE+ + R + +R E++++ +E E K R R+
Sbjct: 1262 QSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRK 1313
Score = 61.6 bits (148), Expect = 2e-09
Identities = 54/207 (26%), Positives = 111/207 (53%), Gaps = 20/207 (9%)
Query: 294 PHKSRHDLVEHEKYCDQYRFAIEQQNILISNWNKNRKDFIQKAVLTLTEACATHEMESML 353
P K R E +KY ++ E++ +L K R+ ++ E E E +L
Sbjct: 978 PEKRRRQERE-KKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDEL--QQEEEQLL 1034
Query: 354 AKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEISARRRE--KEEEKEKLWKKKELLQR 411
++++K++ L+ + RQ+R +EE+ + E ++ RE + +E E+ ++K+E LQ+
Sbjct: 1035 REEREKRR-----LQERERQYR-EEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQ 1088
Query: 412 AEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQELLERRLME 471
E+++ +++ K++++ +E + R+ + L++ E+ L ER K R++ LER+ E
Sbjct: 1089 -EEEQLLREEPEKRRRQERERQCREEEELQQ-----EEEQLLREEREKRRRQELERQYRE 1142
Query: 472 KKEVALQE---AHEDKERARRLEALRK 495
++EV +E E+ E+ RR E R+
Sbjct: 1143 EEEVQQEEEQLLREEPEKRRRQELERQ 1169
Score = 57.8 bits (138), Expect = 3e-08
Identities = 37/152 (24%), Positives = 80/152 (52%), Gaps = 10/152 (6%)
Query: 347 HEMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEISAR--RREKEEEKEKLWK 404
HE E + K++Q+E R W +EE R E E + +R++EEE+ + W
Sbjct: 438 HEQERREQRLKREQEER--------RDWLKREEETERHEQERRKQQLKRDQEEERRERWL 489
Query: 405 KKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQEL 464
K E +R E++++ ++ +++++ +E ++ + E L++ + + RE+ + R++L
Sbjct: 490 KLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQL 549
Query: 465 LERRLMEKKEVALQEAHEDKERARRLEALRKQ 496
L+R ++ E +E +E+ R + L K+
Sbjct: 550 LKREEEKRLEQERREQRLKREQEERRDQLLKR 581
Score = 56.2 bits (134), Expect = 8e-08
Identities = 54/244 (22%), Positives = 113/244 (46%), Gaps = 30/244 (12%)
Query: 348 EMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKLWKKKE 407
+ E ++++++Q+L + + + Q ++E R E ++ RRE+EEE+ + ++E
Sbjct: 324 QQERREQQEERREQQLRREQEERREQQLRREQEEERREQQL---RREQEEERREQQLRRE 380
Query: 408 LLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLK-----DRERVKYRQ 462
R E++ + ++ +++Q +E ++R Q+L ++L EQ L+ +R K+ Q
Sbjct: 381 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQ 440
Query: 463 ELLERRLMEKKEVALQEAHEDKERARRLEALRKQVAVVAQFDPVRMMSDTMASKARMGIE 522
E E+RL ++E ++E R + RKQ ++ D + ++
Sbjct: 441 ERREQRLKREQEERRDWLKREEETERHEQERRKQ----------QLKRDQEEERRERWLK 490
Query: 523 IEEEFILQKPLFTLNTYNEQQIISDPRLRFEL-ALREAGLHRTLYAKEILPKISPQKPPR 581
+EEE EQQ + +LR E RE L R + + ++ ++ R
Sbjct: 491 LEEE-----------ERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLR 539
Query: 582 KDME 585
++ E
Sbjct: 540 REQE 543
Score = 55.8 bits (133), Expect = 1e-07
Identities = 98/440 (22%), Positives = 191/440 (43%), Gaps = 42/440 (9%)
Query: 61 KEQTLIKQHKQVWWQEYQRLNEVRCKMESEIKSLLNEENIGNECLCDLTNFEQELSEQQC 120
+++ L ++ +Q+ E Q L R + E + + L E+ + + + ++E EQQ
Sbjct: 267 RQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQE 326
Query: 121 TYLKNVINPIQQLRADLKYRQHHTLQHSHPHIEFNSMKVLEEVDFVKKQLKTVFERLRLE 180
+ QQLR + + R+ L+ E+ + ++Q ++LR E
Sbjct: 327 RREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRRE 386
Query: 181 QQ-RIENDLSDWSIKILDHSLEEKTNPLSELPIELESLECPYPDLKSSILSEFYKFTQKY 239
QQ R E L + L + E + E L+ E + QK+
Sbjct: 387 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ------QLRRE--QEEERHEQKH 438
Query: 240 QKKLQDFNLQLEDIYRNCQLSEEDHWIYQAILDQYPGDLFGRRTLYLDMLQRYFPHKSRH 299
+++ ++ L+ E R L E+ +++ + RR L Q +
Sbjct: 439 EQERREQRLKREQEERRDWLKREEE------TERHEQE---RRKQQLKRDQEEERRERWL 489
Query: 300 DLVEHEKYCDQYRFAIEQQNILISNWNKNRKDFIQKAVLTLTEACATHEMESMLAKDKKK 359
L E E+ Q R EQQ L + R+ +++ E E L + +
Sbjct: 490 KLEEEERREQQERR--EQQ--LRREQEERREQRLKR-----------QEEEERLQQRLRS 534
Query: 360 QQELCADLKAKVRQWRAHQEEVARLEMEISARR--REKEEEKEKLWKKKELLQ----RAE 413
+Q+L + + + R+ +EE RLE E +R RE+EE +++L K++E + + E
Sbjct: 535 EQQLRREQEER-REQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKRE 593
Query: 414 KKKKIKKYWAKKKQKWQEMEMRDLQRL--EELKKLIAEQSLKDRERVKYRQELLERRLME 471
+++++++ +++ + E E R QRL EE ++ +Q LK E+ + RQ+ L R E
Sbjct: 594 QEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQE 653
Query: 472 KKEVALQEAHEDKERARRLE 491
++E L+ E++ +RL+
Sbjct: 654 RREQRLKREEEEERLEQRLK 673
Score = 55.5 bits (132), Expect = 1e-07
Identities = 56/251 (22%), Positives = 119/251 (47%), Gaps = 35/251 (13%)
Query: 348 EMESMLAKDKKKQQELCADLKAKVRQWRA----HQEEVARLEMEISARRREKEEEKEKLW 403
E E +L ++++K++ + + RQ+R Q+E L E RRR+ E+EK +
Sbjct: 939 EEEQLLREEREKRRR-----QERERQYRKDKKLQQKEEQLLGEEPEKRRRQ---EREKKY 990
Query: 404 KKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQE 463
+++E LQ+ E++ ++ +++Q+W+ + + +E ++L+ E+ K R + + RQ
Sbjct: 991 REEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQY 1050
Query: 464 LLERRLMEKKEVALQEAHEDKERA------RRLEALRKQVAVVAQFDPVRMMSDTMASKA 517
E L +++E L E E + R R+ E L+++ + + +P + +
Sbjct: 1051 REEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQC 1110
Query: 518 RMGIEIEEEFILQKPLFTLNTYNEQQII---SDPRLRFELALREAGLHRTLYAKEILPKI 574
R E+++E E+Q++ + R R EL + +E L +
Sbjct: 1111 REEEELQQE--------------EEQLLREEREKRRRQELERQYREEEEVQQEEEQLLRE 1156
Query: 575 SPQKPPRKDME 585
P+K R+++E
Sbjct: 1157 EPEKRRRQELE 1167
Score = 54.7 bits (130), Expect = 2e-07
Identities = 56/244 (22%), Positives = 115/244 (47%), Gaps = 37/244 (15%)
Query: 337 VLTLTEACATHEMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVAR-------LEMEIS 389
+ + +AC + + D++K+ D K + Q R +E+ R LE E
Sbjct: 78 IFKVAQACY-YALGQATGLDEEKRAR--CDGKESLLQDRRQEEDQRRFEPRDRQLEEEPG 134
Query: 390 ARRREKEEEKEKLW-------KKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLE- 441
RRR+K +E+E+ +K+E L++ +++++ ++ W +++Q+WQE E R + +
Sbjct: 135 QRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELW-RQRQEWQEREERRAEEEQL 193
Query: 442 ------ELKKLIAEQSLKDRERVKYRQELLERRLMEKKE--VALQEAHEDKERARRLEAL 493
E ++ E+ L+ RE ++ R++ E + +++E + + E+KE +R L
Sbjct: 194 QSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVL 253
Query: 494 RKQVAVVAQFDPVRMMSDTMASKARMGIEIEEEFILQKPLFTLNTYNEQQIISDPRLRFE 553
RK+ + + +P R ++ EEE + + L +++ RLR E
Sbjct: 254 RKEEEKLQEEEPQRQRE----------LQEEEEQLRKLERQELRRERQEEEQQQQRLRRE 303
Query: 554 LALR 557
LR
Sbjct: 304 QQLR 307
Score = 54.3 bits (129), Expect = 3e-07
Identities = 54/228 (23%), Positives = 116/228 (50%), Gaps = 31/228 (13%)
Query: 342 EACATHEMESMLAKDKKKQQELCADLKAKVR-----QWRAHQEEVARLEMEISARRRE-- 394
++C HE E +++ +++EL +L+ K R Q R Q+ V + E E R+RE
Sbjct: 194 QSCKGHETEEFPDEEQLRRRELL-ELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETV 252
Query: 395 -----KEEEKEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAE 449
++ ++E+ +++EL + E+ +K+++ +++++ +E + + L+R ++L++ +
Sbjct: 253 LRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRR---K 309
Query: 450 QSLKDRERVKYRQELLERRLMEKKEVALQEAHEDKERARRLEALRKQVAVVAQFDPVRMM 509
Q + RE+ + R+E ERR E++E ++ ++ RR + LR++
Sbjct: 310 QEEERREQQEERREQQERR--EQQEERREQQLRREQEERREQQLRRE------------- 354
Query: 510 SDTMASKARMGIEIEEEFILQKPLFTLNTYNEQQIISDPRLRFELALR 557
+ + ++ E EEE Q+ EQQ+ + +LR E LR
Sbjct: 355 QEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLR 402
Score = 53.1 bits (126), Expect = 7e-07
Identities = 36/150 (24%), Positives = 88/150 (58%), Gaps = 11/150 (7%)
Query: 348 EMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKLWKKKE 407
E E ++++++Q+ + + + R+ + +E+ R E ++ RRE+EEE+ +++
Sbjct: 311 EEERREQQEERREQQERREQQEERREQQLRREQEERREQQL---RREQEEER-----REQ 362
Query: 408 LLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQELLER 467
L+R +++++ ++ +++Q +E ++R Q+L ++L EQ L+ ++++ Q+L R
Sbjct: 363 QLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL--R 420
Query: 468 RLMEKKEVALQEAHEDK-ERARRLEALRKQ 496
R + + +E HE K E+ RR + L+++
Sbjct: 421 REQQLRREQEEERHEQKHEQERREQRLKRE 450
Score = 51.6 bits (122), Expect = 2e-06
Identities = 93/446 (20%), Positives = 192/446 (43%), Gaps = 55/446 (12%)
Query: 30 QQLRALTEAKKLASASAKLKIRKAMLTSKLSKEQTLIKQHKQVWWQEYQRLNEVRCKMES 89
QQLR E ++ + + ++ + +EQ L ++ ++ Q+ +R E + E
Sbjct: 304 QQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEE-RREQ 362
Query: 90 EIKSLLNEENIGNECLCDLTNFEQELSEQQCTYLKNVINPIQQLRADLKYRQHHTLQHSH 149
+++ EE + EQ+L +Q + + QQLR + + R+ L+
Sbjct: 363 QLRREQEEERREQQL-----RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ 417
Query: 150 PHIEFNSMKVLEEVDFVKKQLKTVFERLRLEQQRIENDLSDWSIKILDHSLEEKTNPLSE 209
++ +E + + + K ER +R + + DW + + E+ +
Sbjct: 418 QLRREQQLRREQEEE--RHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQ 475
Query: 210 LPIELESLECPYPDLKSSILSEFYKFTQKYQKKLQDFNLQLEDIYRNCQLSEEDHWIYQA 269
L + E E LK L E + Q+ +++ Q Q E + + EE+ + Q
Sbjct: 476 LKRDQEE-ERRERWLK---LEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQR 531
Query: 270 ILDQYPGDLFGRRTLYLDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNILISNWNKNR 329
+ + L+R + R L++ E ++ R E++ + + R
Sbjct: 532 LRSE-------------QQLRRE-QEERREQLLKRE---EEKRLEQERREQRLKREQEER 574
Query: 330 KDFIQKAVLTLTEACATHEMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEIS 389
+D + K +++++QQ L + + ++ Q R +EEV RLE E
Sbjct: 575 RDQLLKR------------------EEERRQQRLKREQEERLEQ-RLKREEVERLEQEER 615
Query: 390 ARRREKEEEKEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAE 449
+R K EE E+ ++++ L ++E++++ ++ +++Q QE + L+R EE ++L E
Sbjct: 616 REQRLKREEPEE--ERRQQLLKSEEQEERRQQQLRREQ--QERREQRLKREEEEERL--E 669
Query: 450 QSLK-DRERVKYRQELLERRLMEKKE 474
Q LK + E + QEL E + +E
Sbjct: 670 QRLKREHEEERREQELAEEEQEQARE 695
Score = 50.8 bits (120), Expect = 3e-06
Identities = 111/560 (19%), Positives = 235/560 (41%), Gaps = 91/560 (16%)
Query: 67 KQHKQVWWQEYQRLNEVRCKMESEIKSLLNEENIGNECLCDLTNF--EQELSEQQCTYLK 124
K+ +Q W ++Y++ +E ++ E + LL EE + E+EL +++ L
Sbjct: 1010 KRRRQEWERQYRKKDE----LQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLG 1065
Query: 125 NVINPIQQLRADLKYRQHHTLQHSHPHIEFNSMKVLEEVDFVKKQLKTVFERLRLEQQRI 184
++ + +YR+ LQ EE ++++ + + R Q R
Sbjct: 1066 EERETRRRQELERQYRKEEELQQ-------------EEEQLLREEPEKRRRQERERQCRE 1112
Query: 185 ENDLSDWSIKILDHSLEEKTNPLSELPIELESLECPYPDLKSSILSEFYKFTQKYQKKLQ 244
E +L ++L E++ + LE Y + + E ++ +K+ +
Sbjct: 1113 EEELQQEEEQLLREEREKRRR---------QELERQYREEEEVQQEEEQLLREEPEKRRR 1163
Query: 245 DFNLQLEDIYR-NCQLSEEDHWIYQAILDQYPGDLFGRRTLYLDMLQRYFPHKSRHDLVE 303
+LE YR +L +E+ + + ++ RR +R ++ +L +
Sbjct: 1164 Q---ELERQYREEEELQQEEEQLLREEQEK-------RRQ------ERERQYREEEEL-Q 1206
Query: 304 HEKYCDQYRFAIEQQNILISNWNKNRKDFIQ--KAVLTLTEACATHEMESMLAKDKKKQQ 361
+K +YR +Q++ L W +++ ++ K E ++E +D++ QQ
Sbjct: 1207 RQKRKQRYRDE-DQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQ 1265
Query: 362 ELC--------ADLKAKVRQWRAH-----QEEVARLEMEISARRREKEEEKEKLWKKKEL 408
+L D + + R+W+ +EE E + A+RR+++ ++EK ++E
Sbjct: 1266 DLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREER 1325
Query: 409 LQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQ---------SLKDRERVK 459
++ +++ +K+ +++Q QE E + L+R E +K E+ L++ +R++
Sbjct: 1326 EEKRRRQETDRKF-REEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLR 1384
Query: 460 YRQELLERRLMEKKEVALQEAHED--KERARRLEALRKQVAVVAQFDPVRMMSDTMASKA 517
RQE + L E++++ QE + ++R R+ +Q++ + R + +
Sbjct: 1385 -RQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQE 1443
Query: 518 RMGIEIEEEFILQKPLF--------TLNTYNEQQIISDPR----LRFELALREAGLHRTL 565
R +EEE L++ L EQQ+ R L E LR R
Sbjct: 1444 RERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKF 1503
Query: 566 YAKEILPKISPQKPPRKDME 585
+E + Q+P RK +E
Sbjct: 1504 REQE----LRSQEPERKFLE 1519
Score = 50.1 bits (118), Expect = 6e-06
Identities = 95/506 (18%), Positives = 208/506 (41%), Gaps = 70/506 (13%)
Query: 16 KNEMRNIKYKPVDYQQLRALTEAKKLASASAKLKIRKAMLTSKLSKEQTLIKQHKQVWWQ 75
+ E R ++ + Y++ L + ++ + R+ L + KE+ L ++ +Q+ +
Sbjct: 1037 EREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLRE 1096
Query: 76 EYQRLN----EVRCKMESEIKS----LLNEENIGN--ECLCDLTNFEQELSEQQCTYLKN 125
E ++ E +C+ E E++ LL EE + L E+E+ +++ L+
Sbjct: 1097 EPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLRE 1156
Query: 126 VINPIQQLRADLKYRQHHTLQHSHPHI-EFNSMKVLEEVDFVKKQLKTVFERLRLEQQRI 184
++ + +YR+ LQ + K +E + ++ + + + R ++ R
Sbjct: 1157 EPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRD 1216
Query: 185 ENDLSDWSIKILDHSLEEKTNPLSELPIELESLECPYPDLKSSILSEFYKFTQKYQKKLQ 244
E+ SD L+ + P E + + C ++ +
Sbjct: 1217 EDQRSD---------LKWQWEPEKENAVRDNKVYCK-------------------GRENE 1248
Query: 245 DFNLQLEDIYRNCQLSEEDHWIYQAILDQYPGDLFGRRTLYLDMLQRYFPHKSRHDLVEH 304
F QLED + S++D + + +Q D R + R+FP + + + E
Sbjct: 1249 QFR-QLEDSQLRDRQSQQD--LQHLLGEQQERDREQERRRW-QQRDRHFPEEEQLEREEQ 1304
Query: 305 EKYCDQYRFAIEQQNILISNWNKNRKDFIQKAVLTLTEACATHEMESMLAKDKKKQQELC 364
++ + R + E++ +L + R+ E E L +++++Q
Sbjct: 1305 KEAKRRDRKSQEEKQLLREEREEKRRR---------QETDRKFREEEQLLQEREEQPLRR 1355
Query: 365 ADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKLWKKKELLQRAEKKK------KI 418
+ K R+ +E R +E R R +E E++ + K+E R ++++ +
Sbjct: 1356 QERDRKFREEELRHQEQGRKFLEEEQRLRRQERERK--FLKEEQQLRCQEREQQLRQDRD 1413
Query: 419 KKYWAKKKQ--------KWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQELLERRLM 470
+K+ +++Q K++E E + ++ E K L EQ L+ K+R+E E+ L
Sbjct: 1414 RKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREE--EQLLQ 1471
Query: 471 EKKEVALQEAHEDKERARRLEALRKQ 496
E++E L D++ + LR+Q
Sbjct: 1472 EREEQQLHRQERDRKFLEEEQQLRRQ 1497
Score = 49.3 bits (116), Expect = 1e-05
Identities = 88/428 (20%), Positives = 184/428 (42%), Gaps = 53/428 (12%)
Query: 75 QEYQRLNEVRCKMESEIKSLLNEENIGNECLCDLTNFEQELSEQQCTYLKNVINPIQQLR 134
Q+ +R + R E E K E + L E++L E++ + + +QLR
Sbjct: 227 QQQRRERQDRVFQEEEEKEWRKRETV-------LRKEEEKLQEEEPQRQRELQEEEEQLR 279
Query: 135 ADLKYRQHHTLQHSHPHIEFNSMKVLEEVDFVKKQLKTVFERLRLEQQRIENDLSDWSIK 194
+ L+ E ++ E +KQ + R + E++R + + + +
Sbjct: 280 K----LERQELRRERQEEEQQQQRLRREQQLRRKQEEE--RREQQEERREQQERREQQEE 333
Query: 195 ILDHSLEEKTNPLSELPIELESLECPYPDLKSSILSEFYKFTQKYQKKLQDFNLQLEDIY 254
+ L + E + E E + + L + ++ Q+ ++ L+ E
Sbjct: 334 RREQQLRREQEERREQQLRREQEE----ERREQQLRREQEEERREQQLRREQQLRREQQL 389
Query: 255 RNCQLSEEDHWIYQAILDQYPGDLFGRRTLYLDMLQRYFPHKSRHDLVEHEKYCDQYRFA 314
R Q + + + + L + L + R + RH+ +HE+ + R
Sbjct: 390 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQ-KHEQERREQRLK 448
Query: 315 IEQQNILISNWNKNRKDFIQKAVLTLTEACATHEMESMLAKDKKKQQELCADLKAKVRQW 374
EQ+ R+D++++ E HE E + K+ Q+E + +W
Sbjct: 449 REQEE---------RRDWLKRE-----EETERHEQERRKQQLKRDQEE------ERRERW 488
Query: 375 RAHQEEVARLEMEISAR--RREKEEEKEKLWKKKE----LLQRAEKKKKIKKYWAKKKQK 428
+EE R + E + RRE+EE +E+ K++E L QR ++++++ +++++
Sbjct: 489 LKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRR--EQEERR 546
Query: 429 WQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQELLERRLMEKKEVALQEAHEDK--ER 486
Q ++ + +RLE+ ++ EQ LK RE+ + R +LL+R E+++ L+ E++ +R
Sbjct: 547 EQLLKREEEKRLEQERR---EQRLK-REQEERRDQLLKRE-EERRQQRLKREQEERLEQR 601
Query: 487 ARRLEALR 494
+R E R
Sbjct: 602 LKREEVER 609
Score = 49.3 bits (116), Expect = 1e-05
Identities = 44/209 (21%), Positives = 101/209 (48%), Gaps = 9/209 (4%)
Query: 358 KKQQELCADLKAKVRQWRAHQEEVAR---LEMEISARRREKEEEKEKLWKKKELLQRAEK 414
+++Q+L + + + Q ++++ R L E RR ++EE E+ +++ QR ++
Sbjct: 390 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKR 449
Query: 415 KKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQELLERRLMEKKE 474
+++ ++ W K++++ + E +R ++LK+ +Q + RER +E R E++E
Sbjct: 450 EQEERRDWLKREEETERHEQE--RRKQQLKR---DQEEERRERWLKLEEEERREQQERRE 504
Query: 475 VALQEAHEDKERARRLEALRKQVAVVAQFDPVRMMSDTMASKARMGIEIEEEFILQKPLF 534
L+ E++ R +RL+ ++ + + + + + ++ EEE L++
Sbjct: 505 QQLRREQEER-REQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERR 563
Query: 535 TLNTYNEQQIISDPRLRFELALREAGLHR 563
EQ+ D L+ E R+ L R
Sbjct: 564 EQRLKREQEERRDQLLKREEERRQQRLKR 592
Score = 48.9 bits (115), Expect = 1e-05
Identities = 98/481 (20%), Positives = 201/481 (41%), Gaps = 50/481 (10%)
Query: 33 RALTEAKKLASASAKLKIRKAMLTSKLSKEQTLIKQHKQVWWQEYQRLNEVRCKMESEIK 92
R E ++L + +R+ K +E+ ++ + + +E QRL + E E K
Sbjct: 1336 RKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLR----RQERERK 1391
Query: 93 SLLNEENIGNECLCDLTNFEQELSEQQCTYLKNVINPIQQLRADLKYRQHHTLQHSHPHI 152
L E+ + + EQ+L + + + + + D K+R+ +
Sbjct: 1392 FLKEEQQLRCQ------EREQQLRQDRDRKFREEEQQLSRQERDRKFRE----EEQQVRR 1441
Query: 153 EFNSMKVLEEVDFVKKQLKTVF-ERLRLEQQRIENDL--SDWSIKILDHSLEEKTNPLSE 209
+ K LEE ++++ F E +L Q+R E L + K L+ EE+ E
Sbjct: 1442 QERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLE---EEQQLRRQE 1498
Query: 210 LPIELESLECPYPDLKSSILSEFYKF-TQKYQKKLQDFNLQLEDIYRNCQLSE------- 261
+ E + + L E + Q+ Q+K QL R Q +
Sbjct: 1499 RDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFR 1558
Query: 262 EDHWIYQAILDQYPGDLFGRRTLYLDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNIL 321
E+ + Q +Q R L+ Q+ + +E E+ Q R QQ +
Sbjct: 1559 EEEQLRQEREEQQLSRQERDRKFRLEE-QKVRRQEQERKFMEDEQ---QLRRQEGQQQLR 1614
Query: 322 ISNWNKNRKDFIQKAVLTLTEACATHEME--------SMLAKDKKKQQELCADLKAKVRQ 373
K R+D + +L E H E + ++++Q+L D K R+
Sbjct: 1615 QERDRKFRED---EQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFRE 1671
Query: 374 WRAHQEEVARLEMEISARRREKEEEKEKL---WKKKELLQRAE--KKKKIKKYWAKKKQK 428
+E ++ R R+ EE+++L ++++ LQ + +++++++ + +++Q
Sbjct: 1672 EEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQL 1731
Query: 429 WQEMEMRDLQRLEELKKLIAEQSLK-DRERVKYRQELLERRLMEKKEVALQEAHEDKERA 487
QE E L+R E +K++ E+ L+ +RE + R++ +R+ E++++ QE E + R+
Sbjct: 1732 RQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLR-QEREEQQLRS 1790
Query: 488 R 488
+
Sbjct: 1791 Q 1791
Score = 47.8 bits (112), Expect = 3e-05
Identities = 90/473 (19%), Positives = 190/473 (40%), Gaps = 49/473 (10%)
Query: 30 QQLRALTEAKKLASASAKLKIRKAMLTSKLSKEQTLIKQHKQVWWQEYQRLNEVRCKMES 89
QQLR E ++ K + + L +L EQ L ++ ++ Q +R E R + E
Sbjct: 505 QQLRREQEERR--EQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQER 562
Query: 90 EIKSLLNEENIGNECLC--DLTNFEQELSEQQCTYLKNVINPIQQLRADLKYRQHHTLQH 147
+ L E+ + L + +Q L +Q L+ + + R + + R+ L+
Sbjct: 563 REQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKR 622
Query: 148 SHPHIEFNSMKVLEEVDFVKKQLKTVFERLRLEQQRIENDLSDWSIKIL---DHSLEEKT 204
P E + E ++Q + E+ +QR++ + + ++ +H E +
Sbjct: 623 EEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERRE 682
Query: 205 NPLSELPIELESLECPYPDLKSSILSEFYKFTQKYQKKLQ-DFNLQLEDIYRNCQLSEED 263
L+E E E +KS I K+Q +L+ + + + +Y + E
Sbjct: 683 QELAE-----EEQEQARERIKSRI--------PKWQWQLESEADARQSKVYSRPRKQEGQ 729
Query: 264 HWIYQAILDQYPGDLFGRRTLYLDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNILIS 323
Q + RR L + H+ + + EQ+
Sbjct: 730 R------RRQEQEEKRRRRESELQWQEEERAHRQQQEE--------------EQRRDFTW 769
Query: 324 NWNKNRKDFIQKAVLTLTEACATHEMESMLAKDKKKQQELCA----DLKAKVRQWRAHQE 379
W K + L+ + A++++++++ + + + RQ R ++
Sbjct: 770 QWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREK 829
Query: 380 EVARLEMEISARRREKEEEKEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQR 439
E+ LE E +RRE+ ++ L ++++ LQ +++++ ++ +K +WQ E R +R
Sbjct: 830 ELQFLEEEEQLQRRERAQQ---LQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRR 886
Query: 440 LE-ELKKLIAEQSLKDRERVKYRQELLERRLMEKKEVALQEAHEDKERARRLE 491
K + EQ K+++ ++ +E L+R EK+ QE +E + E
Sbjct: 887 HTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQE 939
Score = 46.6 bits (109), Expect = 6e-05
Identities = 42/161 (26%), Positives = 81/161 (50%), Gaps = 19/161 (11%)
Query: 349 MESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKLWKKKEL 408
++ L K+++ QE +L+ + R+ R QE+ E + + ++EE++ L +++E
Sbjct: 895 LQEQLRKEQQLLQEEEEELQREEREKRRRQEQ----ERQYREEEQLQQEEEQLLREEREK 950
Query: 409 LQRAEKKKKIKKYWAKKKQKWQEM----EMRDLQRLEELKKLIAEQSLKDRERVKYRQEL 464
+R E++++ +K KK Q+ +E E +R E KK E+ L+ E R+E
Sbjct: 951 RRRQERERQYRK--DKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREER 1008
Query: 465 LERRLME-----KKEVALQEAHE----DKERARRLEALRKQ 496
+RR E +K+ LQ+ E ++ RRL+ +Q
Sbjct: 1009 EKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQ 1049
Score = 45.1 bits (105), Expect = 2e-04
Identities = 106/568 (18%), Positives = 232/568 (40%), Gaps = 73/568 (12%)
Query: 30 QQLRALTEAKKLASASAKLKIRKAMLTSKLSKEQTLIKQHKQVWWQEYQRLNEVRCKMES 89
QQLR + ++ + ++R+ +L +EQ L ++ + Q+ +R ++R + E
Sbjct: 375 QQLRREQQLRREQQLRREQQLRREQ---QLRREQQLRREQQLRREQQLRREQQLRREQEE 431
Query: 90 EIKSLLNEENIGNECLCDLTNFEQELSEQQCTYLKNVINPIQQLRADLKYRQHHTLQHSH 149
E EQE EQ+ + Q+ R D R+ T +H
Sbjct: 432 ERHE---------------QKHEQERREQR-------LKREQEERRDWLKREEETERHEQ 469
Query: 150 PHIEFNSMKVLEEVDFVKKQLKTVFERLRLEQQRIENDLSDWSIKILDHSL--EEKTNPL 207
+ +K +E + ++ LK E R +Q+R E L + + L +E+ L
Sbjct: 470 ERRK-QQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERL 528
Query: 208 SELPIELESLECPYPDLKSSILSEFYKFTQKYQKKLQDFNLQLEDIYRNCQLSEEDHWIY 267
+ + L + + +L + ++ +++ ++ L+ E R QL + +
Sbjct: 529 QQRLRSEQQLRREQEERREQLLKR--EEEKRLEQERREQRLKREQEERRDQLLKREEERR 586
Query: 268 QAILDQYPGDLFGRRTLYLDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNILISNWNK 327
Q L + + +R L + ++R + R ++ E+ ++ R QQ + +
Sbjct: 587 QQRLKREQEERLEQR-LKREEVERLEQEERREQRLKREEPEEERR----QQLLKSEEQEE 641
Query: 328 NRKDFIQKAVLTLTEACATHE-----MESMLAKD---KKKQQELCAD--------LKAKV 371
R+ +++ E E +E L ++ ++++QEL + +K+++
Sbjct: 642 RRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRI 701
Query: 372 RQWRAHQEEVARLEMEISARRREKEEEKEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQE 431
+W+ E A R K+E + + +++E +R E + + ++ +Q+ +E
Sbjct: 702 PKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEE 761
Query: 432 MEMRDLQRLEELKKLIAEQSLKDRERVKYRQELLERR--------LMEKKEVALQEAHED 483
+ RD + + E+S + R+R+ R L E+R ++++ L E E
Sbjct: 762 EQRRDFTWQWQAE----EKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEK 817
Query: 484 KERARRLEALRKQVAVVAQFDPVRMMSDTMASKARMGIEIEEEFILQKPLFTLNTYNEQQ 543
++R R+ K++ + + + + + R EEE LQ+ + +++
Sbjct: 818 EQRRRQRREREKELQFLEE-------EEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRR 870
Query: 544 IISDPRLRFELALREAGLHRTLYAKEIL 571
D + R++L TLYAK L
Sbjct: 871 ---DQKWRWQLEEERKRRRHTLYAKPAL 895
Score = 44.7 bits (104), Expect = 2e-04
Identities = 35/165 (21%), Positives = 84/165 (50%), Gaps = 12/165 (7%)
Query: 344 CATHEMESMLAKDKK-KQQELCADLKAKVRQWRAHQEEVARLEME---ISARRREKEEEK 399
C E + +D+K +++E + + R++R +++V R E E + ++ ++E
Sbjct: 1401 CQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERH 1460
Query: 400 EKLWKKKELLQRAEK----KKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDR 455
K ++++LLQ E+ +++ + + +++Q+ + E R +EL+ E+ +
Sbjct: 1461 RKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEE 1520
Query: 456 ERVKYRQELLERRLMEKKEVALQE----AHEDKERARRLEALRKQ 496
E+ +RQ+ + L E++++ QE +D++R R E +Q
Sbjct: 1521 EQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQ 1565
Score = 44.3 bits (103), Expect = 3e-04
Identities = 104/470 (22%), Positives = 200/470 (42%), Gaps = 51/470 (10%)
Query: 30 QQLRALTEAKKLASASAKLKIRKAMLTSKLSKEQTLIKQHKQVWWQEYQRLNEVRCKMES 89
++ + L E ++L + ++R+ +EQ L +Q + ++E ++ +VR + E
Sbjct: 1388 RERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQ--QVR-RQER 1444
Query: 90 EIKSLLNEENIGNECLCDLTNFEQELSEQQCTYL------KNVINPIQQLRA---DLKYR 140
E K L E+ + E EQ L E++ L + + QQLR D K+R
Sbjct: 1445 ERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFR 1504
Query: 141 QHHTLQHSHPHIEFNSMKVLEEVDFVKKQLKTVFERLRLEQQRIENDLSDWSIKILDHSL 200
+ L+ P +F + EE ++Q + F L+ EQQ + + D
Sbjct: 1505 EQE-LRSQEPERKF----LEEEQQLHRQQRQRKF--LQEEQQLRRQERGQQRRQDRDRKF 1557
Query: 201 EEKTNPLSELPIELESLECPYPDLKSSILSEFYKFTQKYQKKLQDFNLQLEDIYRNCQLS 260
E+ E E + L D K + + + ++ +K ++D QL
Sbjct: 1558 REEEQLRQER--EEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQ----------QLR 1605
Query: 261 EEDHWIYQAILDQYPGDLFGRRTLYLDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNI 320
++ Q L Q F L + H+ D E+ R EQQ
Sbjct: 1606 RQEG---QQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQ-- 1660
Query: 321 LISNWNKNRKDFIQKAVLTLTEACATHEMESMLAKDKKKQQELCADLKAKVRQWRAHQEE 380
+++RK ++ +L E E +D+K ++E L+ + R+ + QEE
Sbjct: 1661 --LRHDRDRKFREEEQLLQEGEEQQLRRQE----RDRKFREEE-QQLRRQERERKFLQEE 1713
Query: 381 VARLEMEISARRREKEEEKEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRL 440
E+ + RE+E+ +++ ++E L+R E+ +KI +++Q E E + L+R
Sbjct: 1714 QQLRRQELERKFREEEQLRQE--TEQEQLRRQERYRKI----LEEEQLRPEREEQQLRRQ 1767
Query: 441 EELKKLIAEQSLK-DRERVKYRQELLERRLMEKKEVALQEAHEDKERARR 489
E +K E+ L+ +RE + R + +R+ E++++ QE E + R ++
Sbjct: 1768 ERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLR-QEREEQQLRPQQ 1816
Score = 43.5 bits (101), Expect = 5e-04
Identities = 34/182 (18%), Positives = 93/182 (51%), Gaps = 12/182 (6%)
Query: 327 KNRKDFIQKAVLTLTEACATHEMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEM 386
+ K++ ++ + E E E ++ ++++E L+ + + +EE + +
Sbjct: 241 EEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRL 300
Query: 387 EISARRREKEEE--KEKLWKKKELLQRAEKKKKIKKYWAKKKQ---------KWQEMEMR 435
+ R K+EE +E+ +++E +R E++++ ++ +++Q + QE E R
Sbjct: 301 RREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERR 360
Query: 436 DLQRLEELKKLIAEQSLKDRERVKYRQEL-LERRLMEKKEVALQEAHEDKERARRLEALR 494
+ Q E ++ EQ L+ ++++ Q+L E++L ++++ ++ +++ RR + LR
Sbjct: 361 EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420
Query: 495 KQ 496
++
Sbjct: 421 RE 422
Score = 42.7 bits (99), Expect = 0.001
Identities = 40/151 (26%), Positives = 79/151 (52%), Gaps = 18/151 (11%)
Query: 350 ESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEE----EKEKLWKK 405
E L ++++QQ L+ + R + +EE R E E R ++ + E+E+L ++
Sbjct: 1752 EEQLRPEREEQQ-----LRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQE 1806
Query: 406 KELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQELL 465
+E Q +++ K W +++ + +E E R R E ++ AE+ +E K R+E
Sbjct: 1807 REEQQLRPQQRDGKYRWEEEQLQLEEQEQR--LRQERDRQYRAEEQFATQE--KSRRE-- 1860
Query: 466 ERRLMEKKEVALQEAHEDKERARRLEALRKQ 496
E+ L +++E Q+ +++ER R E +R+Q
Sbjct: 1861 EQELWQEEE---QKRRQERERKLREEHIRRQ 1888
Score = 39.7 bits (91), Expect = 0.008
Identities = 38/160 (23%), Positives = 80/160 (50%), Gaps = 15/160 (9%)
Query: 348 EMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEK-------E 400
E + + +++ +Q+ D K + + + E +L + R+ EE+K
Sbjct: 1536 EEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQER 1595
Query: 401 KLWKKKELLQRAEKKKKIKKYWAKK----KQKWQEMEMRDLQRLEELKKLIAEQ-SLKDR 455
K + ++ L+R E ++++++ +K +Q QE E + L R E +K + E+ L+ +
Sbjct: 1596 KFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQ 1655
Query: 456 ERVKYRQELLERRLMEKKEVALQEAHEDKERARRLEALRK 495
ER + + +R+ E++++ LQE E ++ RR E RK
Sbjct: 1656 EREQQLRHDRDRKFREEEQL-LQEGEE--QQLRRQERDRK 1692
Score = 39.3 bits (90), Expect = 0.010
Identities = 48/240 (20%), Positives = 103/240 (42%), Gaps = 20/240 (8%)
Query: 350 ESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKLWKKKELL 409
E L + ++ QQ + + R + +EE R E E R++ + K +L ++K
Sbjct: 1537 EQQLRRQERGQQ------RRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRR 1590
Query: 410 QRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQELLERRL 469
Q E+K + ++++ Q++ ++ E EQ L++RE + ++ +R+
Sbjct: 1591 QEQERKFMEDEQQLRRQEGQQQLRQERDRKFRE-----DEQLLQEREEQQLHRQERDRKF 1645
Query: 470 MEKKEVALQEAHEDKERARRLEALRKQVAVVAQFDPVRMMSDTMASKARMGIEIEEEFIL 529
+E++ ++ E + R R R++ ++ + + ++ K R EEE L
Sbjct: 1646 LEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFR-----EEEQQL 1700
Query: 530 QKPLFTLNTYNEQQIIS----DPRLRFELALREAGLHRTLYAKEILPKISPQKPPRKDME 585
++ E+Q + + + R E LR+ L +E KI ++ R + E
Sbjct: 1701 RRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPERE 1760
Score = 38.5 bits (88), Expect = 0.018
Identities = 45/216 (20%), Positives = 92/216 (42%), Gaps = 38/216 (17%)
Query: 312 RFAIEQQNILISNWNKNRKDFIQKAVLTLTEACATHEMESMLAKDKKKQQELCADLKAKV 371
+F E+Q + ++RK ++ +L E H E +++QQ + K
Sbjct: 1447 KFLEEEQQL---RQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKF 1503
Query: 372 RQWRAHQEEVAR------------------LEMEISARRRE-------------KEEEKE 400
R+ +E R L+ E RR+E +EEE+
Sbjct: 1504 REQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQL 1563
Query: 401 KLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKY 460
+ ++++ L R E+ +K + ++K + QE E + ++ ++L++ +Q L+ K+
Sbjct: 1564 RQEREEQQLSRQERDRKFR--LEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKF 1621
Query: 461 RQELLERRLMEKKEVALQEAHEDKERARRLEALRKQ 496
R++ E+ L E++E L D++ LR+Q
Sbjct: 1622 RED--EQLLQEREEQQLHRQERDRKFLEEEPQLRRQ 1655
Score = 36.6 bits (83), Expect = 0.067
Identities = 46/167 (27%), Positives = 81/167 (48%), Gaps = 23/167 (13%)
Query: 355 KDKKKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEK--------EKLWKKK 406
+D+K ++E L+ + + + +E R E R+E+EE++ + W+++
Sbjct: 1769 RDRKFREE--EQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEE 1826
Query: 407 EL-LQRAE---KKKKIKKYWAKKKQKWQEMEMRDLQRL--EELKKLIAEQSLKDRERVKY 460
+L L+ E ++++ ++Y A+++ QE R+ Q L EE +K E+ K RE
Sbjct: 1827 QLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIR 1886
Query: 461 RQELLERRLMEKKEVALQEAHEDKERARRLEALRKQVAVVAQFDPVR 507
RQ+ E+R + E+ QE K R LE Q A V PVR
Sbjct: 1887 RQQKEEQRHRQVGEIKSQEG---KGHGRLLEPGTHQFASV----PVR 1926
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 64.7 bits (156), Expect = 2e-10
Identities = 95/427 (22%), Positives = 190/427 (44%), Gaps = 58/427 (13%)
Query: 30 QQLRALTEAKKLASASAKLKIRKA-MLTSKLSKEQTLIKQHKQVWWQEYQRLNEVRCKME 88
+Q+R A A A I+ A +L K + Q + + + +E+QR+ R +E
Sbjct: 517 EQIRNQLTAMSSVLAKALEVIKPAHILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIE 576
Query: 89 SEIKSLLNEENIGNECLCDLTNFEQELSEQQCTYLKNVINPIQQLRADLKYRQHHTLQHS 148
E K L NI E ++EL +++ K ++LR + K R+
Sbjct: 577 -ERKERLESLNIQRE--------KEELEQREAELQKVRKAEEERLRQEAKEREKE----- 622
Query: 149 HPHIEFNSMKVLEEVDFVKKQLKTVFERLRLEQQRIENDLSDWSIKILDHSLEEKTNPLS 208
++L+E + +KK KTV ERL +Q + +L + K +D E+ +P
Sbjct: 623 ---------RILQEHEQIKK--KTVRERL---EQIKKTELGAKAFKDIDIEDLEELDPDF 668
Query: 209 ELPIELESLECPYPDLKSSILSEFYKFTQ-KYQKKLQDFNLQLEDIYRNCQLSEEDHWIY 267
+ ++E LE +L+ + ++ K + K+L++ L ++ Y ++ + D W
Sbjct: 669 IMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPL-IKSAYEEQRIKDMDLWEQ 727
Query: 268 QAILDQYPGDLFGRRTLYLDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNILISNWNK 327
Q + T+ L+ ++ HK+R + +E +++ +
Sbjct: 728 Q--------EEERITTMQLER-EKALEHKNRMSRM------------LEDRDLFVMRLKA 766
Query: 328 NRKDFIQKAVLTLTEACATHEMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEME 387
R+ ++ + E A E + L + K++++E + ++ +R +EE R E
Sbjct: 767 ARQSVYEEKLKQFEERLA-EERHNRLEERKRQRKE-----ERRITYYREKEEEEQRRAEE 820
Query: 388 ISARRREKEEEKEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLI 447
+ RE+ E E+ +++EL + E+ KK+++ KK+Q+ E+E R+ +R EE +
Sbjct: 821 QMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGD 880
Query: 448 AEQSLKD 454
+ S KD
Sbjct: 881 SSLSRKD 887
Score = 42.0 bits (97), Expect = 0.002
Identities = 52/202 (25%), Positives = 97/202 (48%), Gaps = 40/202 (19%)
Query: 353 LAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEK---LWKKKELL 409
L K+KK+ QE + + K+ + E RLE EI + EE++ K LW+++E
Sbjct: 677 LEKEKKELQERLKNQEKKIDYF----ERAKRLE-EIPLIKSAYEEQRIKDMDLWEQQEEE 731
Query: 410 QRAEKKKKIKKYWAKKKQKWQEMEMRDL--------------QRLEELKKLIAEQS---L 452
+ + + +K K + + +E RDL ++L++ ++ +AE+ L
Sbjct: 732 RITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRL 791
Query: 453 KDRERVK--------YRQ-ELLERRLMEKKEVALQEAHEDKERARRLEALRKQVAVVAQF 503
++R+R + YR+ E E+R E++ + +E E ERA+R E LR+
Sbjct: 792 EERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQ------ 845
Query: 504 DPVRMMSDTMASKARMGIEIEE 525
+ V+ + + K + +EIEE
Sbjct: 846 ERVKKLEEVERKKRQRELEIEE 867
Score = 33.9 bits (76), Expect = 0.43
Identities = 30/186 (16%), Positives = 89/186 (47%), Gaps = 19/186 (10%)
Query: 349 MESMLAKDKKKQQELCADLKAK----VRQWRAHQEEVARLEMEISARRREKEEEKEKLWK 404
++SM ++ + Q + + AK ++ QE+ + ++ ++A + +E +++
Sbjct: 511 LQSMPSEQIRNQLTAMSSVLAKALEVIKPAHILQEKEEQHQLAVTAYLKNSRKEHQRILA 570
Query: 405 KKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQEL 464
+++ ++ E+K++++ +++++ E +LQ++ + ++ Q K+RE+
Sbjct: 571 RRQTIE--ERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKE------ 622
Query: 465 LERRLMEKKEVALQEAHEDKERARRLEALRK-----QVAVVAQFDPVRMMSDTMASKARM 519
R L E +++ + E E+ ++ E K + + + DP +M+ + +
Sbjct: 623 --RILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKE 680
Query: 520 GIEIEE 525
E++E
Sbjct: 681 KKELQE 686
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 63.9 bits (154), Expect = 4e-10
Identities = 77/388 (19%), Positives = 166/388 (42%), Gaps = 32/388 (8%)
Query: 158 KVLEEVDFVKKQLKTVFERLRLEQQRIENDLSDWSIKILDHSLEEKTNPLSE----LPIE 213
+ L V KK+ E L E+ + +L + I D L+EK L E + E
Sbjct: 240 QALSAVATQKKKADRYIEELTKERDALSLEL--YRNTITDEELKEKNAKLQEKLQLVESE 297
Query: 214 LESLECPYPDLKSSI-LSEFYKFTQKYQKKLQDFNLQLEDIYRNCQLSEEDHWIYQAILD 272
++ +LK + ++ Q+ Q + +L+ + Q E++ ++ L+
Sbjct: 298 KSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNR-LN 356
Query: 273 QYPGDLFGRRTLYLDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNILISN-------- 324
Q + R+ + + + + EK +Q Q+ ++
Sbjct: 357 QQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQE 416
Query: 325 ---WNKNRKDFIQKAVLTLTEACATHEMESMLAKDKKKQQELCADLKAKVRQWRAHQEEV 381
W K K Q+ ++ E E M ++K ++QE + K+R+ QE+
Sbjct: 417 EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 476
Query: 382 ARL---EMEISARRREKEEEKEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQ 438
A++ E +I + + E++EK+W+++E + EK ++ +K +++ QE ++R+ +
Sbjct: 477 AKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQE 536
Query: 439 RLEELKKLIAEQSLKDRERVKYRQELLERRLMEKKEVALQEAHEDKERARRLEALRKQVA 498
+ K+ I EQ E+++ ++E + R+ E+K E+K R + + R++
Sbjct: 537 EIWRQKEKIHEQ----EEKIRKQEEKMWRQ--EEK----MHDQEEKIREQEEKVWRQEEK 586
Query: 499 VVAQFDPVRMMSDTMASKARMGIEIEEE 526
+ Q + +R + + + M E EE+
Sbjct: 587 IREQEEKIREQEEKIREQEEMTQEQEEK 614
Score = 62.8 bits (151), Expect = 9e-10
Identities = 94/463 (20%), Positives = 202/463 (43%), Gaps = 54/463 (11%)
Query: 39 KKLASASAKLKIRKAMLTSKLSKEQTLIKQHKQVWWQEYQRLNEVRCKMESEIKSLLNEE 98
++L +AKL+ + ++ S+ S+ Q +K+ K+ + L + + + E++
Sbjct: 278 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEAD-------- 329
Query: 99 NIGNECLCDLTNFEQELSEQQCTYLKNVINPIQQLRADLKYRQHHTLQHSHPHIEFNSMK 158
++G E + ++ E + + N + Q + + +RQ +Q I+ K
Sbjct: 330 HLGKELQSVSAKLQAQVEENE------LWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEK 383
Query: 159 VLEEVDFVKKQLKTVFERLRLEQQRIENDLSDWSIKILDHSLEEKTNPLSELPIELESLE 218
+ E+ + +++Q E++R +++ + W EEK E+ E E
Sbjct: 384 IREQEEKIREQE----EKMRRQEEMM------WE-------KEEKMRRQEEMMWEKEE-- 424
Query: 219 CPYPDLKSSILSEFYKFTQKYQKKLQDFNLQLEDIYRNCQLSEEDHWIYQAILDQYPGDL 278
K E ++ ++L++ + E I + +E+ I + Q
Sbjct: 425 ------KMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 478
Query: 279 FGRRTLYLDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNILISN-WNKNRKDFIQKAV 337
R+ + + + + EK +Q + E++ W + K Q+ +
Sbjct: 479 MWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI 538
Query: 338 LTLTEACATHEMESMLAKDKKK---QQELCADLKAKVRQWRAHQEEVARLEMEISARRRE 394
E HE E + K ++K Q+E D + K+R+ +E+V R E +I + +
Sbjct: 539 WRQKEKI--HEQEEKIRKQEEKMWRQEEKMHDQEEKIRE---QEEKVWRQEEKIREQEEK 593
Query: 395 KEEEKEKLWKKKELLQRAEKKK-KIKKYWAKKKQKWQEME---MRDLQRLEELKKLIAEQ 450
E++EK+ +++E+ Q E+K + ++ ++++K QE E R +++ E +K I EQ
Sbjct: 594 IREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQ 653
Query: 451 SLKDRERVKYRQELLERRLMEKKEVALQE--AHEDKERARRLE 491
K RE+ + QE E+ +++++ QE E +E+ RR E
Sbjct: 654 EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 696
Score = 59.3 bits (142), Expect = 1e-08
Identities = 50/189 (26%), Positives = 95/189 (50%), Gaps = 15/189 (7%)
Query: 358 KKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKLWKKKELLQRAEKK-- 415
++Q+E + K+ + +EE R E E R+ EK E+E++W++KE + E+K
Sbjct: 494 REQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIR 553
Query: 416 KKIKKYW---------AKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQELLE 466
K+ +K W +K ++ +E R +++ E ++ I EQ K RE+ + QE E
Sbjct: 554 KQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEE 613
Query: 467 RRLMEKKEVALQE--AHEDKERARRL-EALRKQVAVV-AQFDPVRMMSDTMASKARMGIE 522
+ +++++ QE E +E+ RR E +R+Q + Q + +R + M + E
Sbjct: 614 KMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 673
Query: 523 IEEEFILQK 531
EE+ Q+
Sbjct: 674 QEEKMCEQE 682
Score = 48.1 bits (113), Expect = 2e-05
Identities = 74/422 (17%), Positives = 184/422 (43%), Gaps = 34/422 (8%)
Query: 30 QQLRALTE--AKKLASASAKLK--IRKAMLTSKLSKEQTLIKQHKQVWWQEYQRLNEVRC 85
QQL+A + K+L S SAKL+ + + L ++L+++Q ++ W++ +++ E
Sbjct: 322 QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQ------EEKMWRQEEKIQEWEE 375
Query: 86 KMESEIKSLLNEENIGNECLCDLTNFEQELSEQQCTYLKNVINPIQQLRADLKYRQHHTL 145
K++ + + + +E E + E+ + E++ + + + + RQ +
Sbjct: 376 KIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQ--EEMMWEKEEKMRRQEEMM 433
Query: 146 QHSHPHIEFNSMKVLEEVDFVKKQLKTVFE-RLRLEQQRIENDLSDWSIKILDHSLEEKT 204
I K+ E+ +++ K E ++R +++R E + W + EEK
Sbjct: 434 WEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI 493
Query: 205 NPLSELPIELESLECPYPDLKSSILSEFYKFTQKYQKKLQDFNLQLEDIYRNCQLSEEDH 264
E E + E K ++ +++ Q+ + E+ R +E+
Sbjct: 494 REQEEKMWRQEEK-----------IHEQEKIREEEKRQEQEEMWRQEEKIRE----QEEI 538
Query: 265 WIYQAILDQYPGDLFGRRTLYLDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNILISN 324
W + + + + R+ Q H + E E+ + I +Q I
Sbjct: 539 WRQKEKIHEQEEKI--RKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKI-- 594
Query: 325 WNKNRKDFIQKAVLTLTEACATHEMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARL 384
+ + ++ +T + E E + + ++K QE ++ + + R ++++
Sbjct: 595 -REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQ 653
Query: 385 EMEISARRREKEEEKEKLWKKKE-LLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEEL 443
E +I + +E++EK+W+++E + ++ EK ++ ++ ++++K E E+R Q+ E++
Sbjct: 654 EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKM 713
Query: 444 KK 445
++
Sbjct: 714 QE 715
Score = 40.4 bits (93), Expect = 0.005
Identities = 81/475 (17%), Positives = 206/475 (43%), Gaps = 40/475 (8%)
Query: 22 IKYKPVDYQQLRALTEAKKLASASAKLKIRKAMLTSKLSKEQTLIKQHKQVWWQEY--QR 79
+K K Q+ L E++K +++++ L KL + + L+ Q + ++ +
Sbjct: 280 LKEKNAKLQEKLQLVESEK-----SEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKE 334
Query: 80 LNEVRCKMESEIKSLLNEENIGNECLCDLTNFEQELSEQQCTYLKNVINPIQQLRADLKY 139
L V K++++++ NE L ++E +Q ++ IQ+ ++
Sbjct: 335 LQSVSAKLQAQVEE--------NELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR- 385
Query: 140 RQHHTLQHSHPHIEFNSMKVLEEVDFVKKQLKTVFERLRLEQQRIENDL---SDWSIKIL 196
Q ++ + + E+ + +++Q + ++E+ E+ R + ++ + I+ L
Sbjct: 386 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE--EKMRRQEEMMWEKEEKIREL 443
Query: 197 DHSLEEKTNPLSELPIELESLECPYPDLKSSILSEFYKFTQKYQKKLQDFNLQLEDIYRN 256
+ + E+ + E + + + ++ ++ +K +++ + Q E ++R
Sbjct: 444 EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQ 503
Query: 257 CQLSEEDHWIYQAILDQYPGDLFGRRTLYLDMLQRYFPHKSRHDLVEHEKYCDQYRFAIE 316
+ E I + Q +++ + + + + + H+ + EK Q
Sbjct: 504 EEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHE--QEEKIRKQEEKMWR 561
Query: 317 QQNILISNWNKNRKDFIQKAVLTLTEACATHEMESMLAKDK-KKQQELCADLKAKVRQWR 375
Q+ + K R+ ++ V E E + ++K ++Q+E+ + + K+ +
Sbjct: 562 QEEKMHDQEEKIREQ--EEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQE 619
Query: 376 ---AHQEEVARLEMEISARRREKEEEKEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEM 432
QEE + + E R+ EK E+EK +++E EK ++ ++ ++++K E
Sbjct: 620 EKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQE-----EKIREQEEMMQEQEEKMWEQ 674
Query: 433 EMRDLQRLEELKKLIAEQSLKDRERVKYRQELLERRLMEKKEVALQEAHEDKERA 487
E + ++ E++++ E+ ++ +E + QE+ R+ EK +QE E E A
Sbjct: 675 EEKMCEQEEKMQE--QEEKMRRQEEKMWEQEVRLRQQEEK----MQEHQEHLEAA 723
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 63.5 bits (153), Expect = 5e-10
Identities = 47/160 (29%), Positives = 90/160 (56%), Gaps = 14/160 (8%)
Query: 350 ESMLAKDKKKQQELCADLKAKVRQWRAHQEEVAR----LEMEISARR------REKEEEK 399
E LA++K K++ A K + + R QEE AR L+ E RR ++KEEE+
Sbjct: 615 EERLAEEKAKKK--AAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQ 672
Query: 400 EKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVK 459
E+L K E + AE++++ ++ +++Q+ +E E R+ +R E+ ++L ++ +++ER++
Sbjct: 673 ERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQ 732
Query: 460 YRQELLERR--LMEKKEVALQEAHEDKERARRLEALRKQV 497
+EL ER L +KE +E E K++ + +Q+
Sbjct: 733 AERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQL 772
Score = 54.3 bits (129), Expect = 3e-07
Identities = 39/163 (23%), Positives = 87/163 (53%), Gaps = 15/163 (9%)
Query: 345 ATHEMESMLAKDKKKQQELCADLKAKVRQWRAHQE--------EVARLEMEISARRREKE 396
A +ME + A+ K++++ + + R HQE E RL A+R ++
Sbjct: 628 AAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQ 687
Query: 397 EEKEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRE 456
E+E+ +++ +R E++++ +++++ QE ++ + +R E ++L AE+ L++RE
Sbjct: 688 REQERREQERREQERREQERR------EQERREQERQLAEQERRREQERLQAERELQERE 741
Query: 457 R-VKYRQELLERRLMEKKEVALQEAHEDKERARRLEALRKQVA 498
+ ++ ++E L+R L EKK+ Q+ +++ E K+ A
Sbjct: 742 KALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAA 784
Score = 52.4 bits (124), Expect = 1e-06
Identities = 50/209 (23%), Positives = 115/209 (55%), Gaps = 19/209 (9%)
Query: 358 KKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKLWKKKELLQRAEKK-- 415
K+++ L L+A+ R + +E+ ++E + + + +E+ EK +++ ++A+KK
Sbjct: 573 KREERLRKVLQARERVEQMKEEKKKQIEQKFA----QIDEKTEKAKEERLAEEKAKKKAA 628
Query: 416 -KKIKKYWAKKKQKWQEMEMRDLQRLEELKK---LIAEQSLKDRERVKYRQE---LLERR 468
KK+++ A++KQ+ + +R LQ+ EE ++ L+ ++ +++ER++ E L E+R
Sbjct: 629 AKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQR 688
Query: 469 LMEKKEVALQEAHEDKERARRLEALRKQVAVVAQ----FDPVRMMSDTMASKARMGIEIE 524
E++E +E E +E+ RR + R+Q +A+ + R+ ++ + + ++
Sbjct: 689 EQERREQERRE-QERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQ 747
Query: 525 EEFILQKPLFTLNTYNEQQIISDPRLRFE 553
+E LQ+ L EQQ +++ +L+ E
Sbjct: 748 KE-QLQRELEEKKKKEEQQRLAERQLQEE 775
Score = 47.4 bits (111), Expect = 4e-05
Identities = 39/168 (23%), Positives = 84/168 (50%), Gaps = 18/168 (10%)
Query: 330 KDFIQKAV-LTLTEACATHEMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEI 388
K FI++ L + C+ E E ++ ++++E E++ R ++E
Sbjct: 517 KSFIKRNTPLRMDPKCSFVEKERQRLENLRRKEEA---------------EQLRRQKVEE 561
Query: 389 SARRREKEEEKEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIA 448
RRR +E + ++ + +++LQ E+ +++K+ KKKQ Q+ D + + ++ +A
Sbjct: 562 DKRRRLEEVKLKREERLRKVLQARERVEQMKE--EKKKQIEQKFAQIDEKTEKAKEERLA 619
Query: 449 EQSLKDRERVKYRQELLERRLMEKKEVALQEAHEDKERARRLEALRKQ 496
E+ K + K +E+ RR E++ L+ +++E R E L+K+
Sbjct: 620 EEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKK 667
Score = 34.7 bits (78), Expect = 0.25
Identities = 34/133 (25%), Positives = 70/133 (52%), Gaps = 13/133 (9%)
Query: 396 EEEKEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDR 455
E+E+++L E L+R E+ +++++ ++ ++ + +E L+R E L+K+ L+ R
Sbjct: 536 EKERQRL----ENLRRKEEAEQLRRQKVEEDKR-RRLEEVKLKREERLRKV-----LQAR 585
Query: 456 ERVKYRQELLERRLMEKKEVALQEAHEDKERARRLEALRKQVAVVAQFDPV--RMMSDTM 513
ERV+ +E +++ +E+K + E E + R E K+ A + + V R +
Sbjct: 586 ERVEQMKE-EKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEE 644
Query: 514 ASKARMGIEIEEE 526
A + R + EEE
Sbjct: 645 ARRLRWLQQEEEE 657
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 63.5 bits (153), Expect = 5e-10
Identities = 47/160 (29%), Positives = 90/160 (56%), Gaps = 14/160 (8%)
Query: 350 ESMLAKDKKKQQELCADLKAKVRQWRAHQEEVAR----LEMEISARR------REKEEEK 399
E LA++K K++ A K + + R QEE AR L+ E RR ++KEEE+
Sbjct: 611 EERLAEEKAKKK--AAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQ 668
Query: 400 EKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVK 459
E+L K E + AE++++ ++ +++Q+ +E E R+ +R E+ ++L ++ +++ER++
Sbjct: 669 ERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQ 728
Query: 460 YRQELLERR--LMEKKEVALQEAHEDKERARRLEALRKQV 497
+EL ER L +KE +E E K++ + +Q+
Sbjct: 729 AERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQL 768
Score = 54.3 bits (129), Expect = 3e-07
Identities = 39/163 (23%), Positives = 87/163 (53%), Gaps = 15/163 (9%)
Query: 345 ATHEMESMLAKDKKKQQELCADLKAKVRQWRAHQE--------EVARLEMEISARRREKE 396
A +ME + A+ K++++ + + R HQE E RL A+R ++
Sbjct: 624 AAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQ 683
Query: 397 EEKEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRE 456
E+E+ +++ +R E++++ +++++ QE ++ + +R E ++L AE+ L++RE
Sbjct: 684 REQERREQERREQERREQERR------EQERREQERQLAEQERRREQERLQAERELQERE 737
Query: 457 R-VKYRQELLERRLMEKKEVALQEAHEDKERARRLEALRKQVA 498
+ ++ ++E L+R L EKK+ Q+ +++ E K+ A
Sbjct: 738 KALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAA 780
Score = 52.4 bits (124), Expect = 1e-06
Identities = 50/209 (23%), Positives = 115/209 (55%), Gaps = 19/209 (9%)
Query: 358 KKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKLWKKKELLQRAEKK-- 415
K+++ L L+A+ R + +E+ ++E + + + +E+ EK +++ ++A+KK
Sbjct: 569 KREERLRKVLQARERVEQMKEEKKKQIEQKFA----QIDEKTEKAKEERLAEEKAKKKAA 624
Query: 416 -KKIKKYWAKKKQKWQEMEMRDLQRLEELKK---LIAEQSLKDRERVKYRQE---LLERR 468
KK+++ A++KQ+ + +R LQ+ EE ++ L+ ++ +++ER++ E L E+R
Sbjct: 625 AKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQR 684
Query: 469 LMEKKEVALQEAHEDKERARRLEALRKQVAVVAQ----FDPVRMMSDTMASKARMGIEIE 524
E++E +E E +E+ RR + R+Q +A+ + R+ ++ + + ++
Sbjct: 685 EQERREQERRE-QERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQ 743
Query: 525 EEFILQKPLFTLNTYNEQQIISDPRLRFE 553
+E LQ+ L EQQ +++ +L+ E
Sbjct: 744 KE-QLQRELEEKKKKEEQQRLAERQLQEE 771
Score = 49.3 bits (116), Expect = 1e-05
Identities = 40/157 (25%), Positives = 79/157 (50%), Gaps = 8/157 (5%)
Query: 346 THEMESMLAKDKKKQQELCADLKAKVRQW------RAHQEEVARLEMEISARRREKEEEK 399
T S++ K+ L D K K RQ + E++ R ++E RRR +E +
Sbjct: 509 TSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKL 568
Query: 400 EKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVK 459
++ + +++LQ E+ +++K+ KKKQ Q+ D + + ++ +AE+ K + K
Sbjct: 569 KREERLRKVLQARERVEQMKE--EKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAK 626
Query: 460 YRQELLERRLMEKKEVALQEAHEDKERARRLEALRKQ 496
+E+ RR E++ L+ +++E R E L+K+
Sbjct: 627 KMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKK 663
Score = 37.0 bits (84), Expect = 0.051
Identities = 36/138 (26%), Positives = 72/138 (52%), Gaps = 13/138 (9%)
Query: 391 RRREKEEEKEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQ 450
R KE+E+++L E L+R E+ +++++ ++ ++ + +E L+R E L+K+
Sbjct: 527 RMDPKEKERQRL----ENLRRKEEAEQLRRQKVEEDKR-RRLEEVKLKREERLRKV---- 577
Query: 451 SLKDRERVKYRQELLERRLMEKKEVALQEAHEDKERARRLEALRKQVAVVAQFDPV--RM 508
L+ RERV+ +E +++ +E+K + E E + R E K+ A + + V R
Sbjct: 578 -LQARERVEQMKE-EKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARR 635
Query: 509 MSDTMASKARMGIEIEEE 526
+ A + R + EEE
Sbjct: 636 KQEEEARRLRWLQQEEEE 653
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 62.8 bits (151), Expect = 9e-10
Identities = 104/499 (20%), Positives = 217/499 (43%), Gaps = 97/499 (19%)
Query: 13 FHMKNEMRNIKYKPVDYQQLRALTEAKKLASASAKLKIRKAMLTSKLSKEQTLIKQHKQV 72
F ++ I+++ ++ + +TE +K+ L + + KLSK +K K
Sbjct: 816 FETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSE 875
Query: 73 WWQEYQRLNEVRCKMESEIKSLLNEENIGNECLCDLTNFEQELSEQQCTYLKNVINPIQQ 132
+ +E Q+ G + DL +EL Q ++N + ++
Sbjct: 876 FEKENQK---------------------GKAAILDLEKTCKELKHQLQVQMENTLKEQKE 914
Query: 133 LRADLKYRQHHTLQHSHPHIEFNSMKVLEEVDFVKKQLKTVFERLRLEQQRIENDLSDWS 192
L+ L+ + + Q +E NSM+ E++ Q + ++ E+Q+++ ++++
Sbjct: 915 LKKSLEKEKEASHQLK---LELNSMQ--EQL----IQAQNTLKQNEKEEQQLQGNINE-- 963
Query: 193 IKILDHSLEEKTNPLSELPIELESLECPYPDLKSSILSEFYKFTQKYQKKLQDFNLQLED 252
L S E+K + L EL+ +L++ + + + Q+ + + ++
Sbjct: 964 ---LKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISV---- 1016
Query: 253 IYRNCQLSEEDHWIYQAILDQYPGDLFGRRTLYLDMLQRYFPHKSRHDLVEHEKYCDQYR 312
+ N + S+E Q D +GR + L +R DL E+ +
Sbjct: 1017 LQNNYEKSQE-------TFKQLQSDFYGRESELL---------ATRQDLKSVEE-----K 1055
Query: 313 FAIEQQNILISNWNK--NRKDFIQKAVLTLTEACATHEMESMLAKDKKKQQELCADLKAK 370
++ Q++ LISN N+ N+ IQ+ L A AT E +S AK +++ QE C L+
Sbjct: 1056 LSLAQED-LISNRNQIGNQNKLIQE----LKTAKATLEQDS--AKKEQQLQERCKALQ-- 1106
Query: 371 VRQWRAHQEEVARLEMEISARRREKEEEKEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQ 430
++ E S + +E EK KL + +E+ + ++K+I K + K
Sbjct: 1107 ------------DIQKEKSLKEKELVNEKSKLAEIEEI--KCRQEKEITKLNEELKSHKL 1152
Query: 431 EMEMRDLQRLEELKKLIAEQSLKDR----------ERVKYRQELLERRLMEKKEVALQEA 480
E ++++ L++ K+L+ +Q L+ + E+ K Q++L+ + ++K+E L++
Sbjct: 1153 E-SIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQ-VKKEEEELKKE 1210
Query: 481 HEDKERARRLEALRKQVAV 499
+KE E K+V +
Sbjct: 1211 FIEKEAKLHSEIKEKEVGM 1229
Score = 58.9 bits (141), Expect = 1e-08
Identities = 113/587 (19%), Positives = 243/587 (41%), Gaps = 91/587 (15%)
Query: 16 KNEMRNIKYKPVDYQQLRALTEAKKLASASAKLKIRKAMLTSKLSKEQTLIKQHKQVWWQ 75
K E +++ K Q L+ L + ++L + L++R L+ +L E+ ++ + +
Sbjct: 734 KLEADSLEVKASKEQALQDLQQQRQL---NTDLELRATELSKQLEMEKEIVSSTRLDLQK 790
Query: 76 EYQRLNEVRCKM--ESEIKSLLNEENIGNECLCDLTNFEQELSEQQCTYLKNVINPIQQL 133
+ + L ++ K+ + E K +L + D QE Q + + N IQ
Sbjct: 791 KSEALESIKQKLTKQEEEKQILKQ---------DFETLSQETKIQH----EELNNRIQTT 837
Query: 134 RADLKYRQHHTLQHSHPHIEFNSMKVLEEVDFVKKQLKTVFERLRLEQQRIENDLSDWSI 193
+L+ ++ ++ E+ VK +L V + L+ + E +
Sbjct: 838 VTELQ------------KVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKA 885
Query: 194 KILDHSLEEKTNPLS-ELPIELESLECPYPDLKSSILSEFYKFTQKYQKKLQDFNLQLED 252
ILD LE+ L +L +++E+ +LK S+ E + + + + +L QL
Sbjct: 886 AILD--LEKTCKELKHQLQVQMENTLKEQKELKKSLEKE-KEASHQLKLELNSMQEQLIQ 942
Query: 253 IYRNCQLSEEDHWIYQAILDQYPGDLFGRRTLYLDMLQRYFPHKSRHDLVEHEKYCDQYR 312
+ +E++ Q +++ S + E + +
Sbjct: 943 AQNTLKQNEKEEQQLQGNINE-------------------LKQSSEQKKKQIEALQGELK 983
Query: 313 FAIEQQNILISNWNKNRKDFIQKAVLTLTEACATHEMESMLAKDKKKQQE----LCADLK 368
A+ Q+ L NK ++ Q A E A E S+L + +K QE L +D
Sbjct: 984 IAVLQKTELE---NKLQQQLTQAA----QELAAEKEKISVLQNNYEKSQETFKQLQSDFY 1036
Query: 369 AKVRQWRAHQEEVARLEMEISARRREKEEEKEKLWKKKELLQRAE-KKKKIKKYWAKKKQ 427
+ + A ++++ +E ++S + + + ++ + +L+Q + K +++ AKK+Q
Sbjct: 1037 GRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQ 1096
Query: 428 KWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQELLE-RRLMEKKEVALQEAHEDKER 486
+ QE R + L+ + E+SLK++E V + +L E + ++E + + +E+ +
Sbjct: 1097 QLQE-------RCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEEL-K 1148
Query: 487 ARRLEALRKQVAVVAQFDPVRMMSDTMASKARMGIEIEEEFILQKPLFTLNTYNEQQIIS 546
+ +LE++++ + + D + +E++ + K N QQI+
Sbjct: 1149 SHKLESIKE----------ITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRN-QQILK 1197
Query: 547 D------PRLRFELALREAGLHRTLYAKEILPKISPQKPPRKDMEST 587
D L+ E +EA LH + KE+ K + + M+ T
Sbjct: 1198 DQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQIT 1244
Score = 45.4 bits (106), Expect = 1e-04
Identities = 104/505 (20%), Positives = 214/505 (42%), Gaps = 66/505 (13%)
Query: 15 MKNEMRNIKYKPVDYQQLRALTEAKKLASASAKLKIRKAMLTSKLSKEQTLIKQHKQVWW 74
+K E+ ++ K YQ L+A E K+L + + L S++++ + + + ++
Sbjct: 377 LKEELSEVETK---YQHLKA--EFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLG 431
Query: 75 QEYQRLNEVRCKMESEIKSLLNEENIGNECLCDLTNFEQELSEQ--QCTYLKNVINPIQQ 132
+ + RL E R ++ SE L+++E + L+ E++L E+ T L++ ++ +Q
Sbjct: 432 EAHGRLKEQR-QLSSE--KLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQ 488
Query: 133 LRADLKYRQHHT---LQHSHPHIEFNSMKVLEEVDFVKKQLKTVFERLRLEQQRIENDLS 189
+ + Q T L+ + +E ++ + + D + L+ + ++ + +E +
Sbjct: 489 QHQEQQALQQSTTAKLREAQNDLE-QVLRQIGDKDQKIQNLEALLQKSKENISLLEKERE 547
Query: 190 DWSIKIL---------------DHSLEEKTNPLSE-LPIELESLECPYPDLKSSILSEFY 233
D KI +H+L+E+ L+E L + ES + +L + +
Sbjct: 548 DLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQ-- 605
Query: 234 KFTQKYQKKLQDFNLQLEDIYR--NCQLSEEDHWIYQA----------ILDQYPGDLFGR 281
+ + + QD L LE N QL+E + Q +L R
Sbjct: 606 ---KAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQR 662
Query: 282 RTL--YLDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNILISNWNKNRKDFIQKAVLT 339
L +LD Q K + +L + DQ ++ + S + K++ +K L+
Sbjct: 663 ADLQNHLDTAQNALQDKQQ-ELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEK-YLS 720
Query: 340 LTEACATHEMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEK 399
L + T E+E + K + E+ A + ++ + ++ LE+ + ++ E EK
Sbjct: 721 LEQK--TEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEK 778
Query: 400 E-------KLWKKKELLQRAEKKKKIKKYWAKK---KQKWQEMEMRDLQRLEELKKLIAE 449
E L KK E L+ K+K+ K +K KQ ++ + + EEL I +
Sbjct: 779 EIVSSTRLDLQKKSEALESI--KQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRI-Q 835
Query: 450 QSLKDRERVKYRQELLERRLMEKKE 474
++ + ++VK +E L L K+
Sbjct: 836 TTVTELQKVKMEKEALMTELSTVKD 860
Score = 41.6 bits (96), Expect = 0.002
Identities = 86/474 (18%), Positives = 191/474 (40%), Gaps = 71/474 (14%)
Query: 28 DYQQLRALTEAKKLASASAKLKIRKAMLTSKLSKEQTLIKQHKQVWWQEYQRLNEVRCKM 87
+ ++L+ E +K AS KL++ + +L + Q +KQ+++ Q +NE++
Sbjct: 911 EQKELKKSLEKEKEASHQLKLELNS--MQEQLIQAQNTLKQNEKEEQQLQGNINELKQSS 968
Query: 88 ESEIKSLLNEENIGNECLCDLTNFEQELSEQQCTYLKNVINPIQQLRADLKYRQHHTLQH 147
E + K + + + T E +L +Q + + ++ + + + Q
Sbjct: 969 EQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELA--AEKEKISVLQNNYEKSQE 1026
Query: 148 SHPHIEFNSMKVLEEVDFVKKQLKTVFERLRLEQQRIENDLSDWSIKILDHSLEEKTNPL 207
+ ++ + E+ ++ LK+V E+L L Q+ + ++ + + + +
Sbjct: 1027 TFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQ---------IGNQNKLI 1077
Query: 208 SELPIELESLECPYPDLKSSILSEFYKFTQKYQKKLQDFNLQLEDIYRNCQLSEEDHWIY 267
EL +LE + + K +++LQ+ L+DI + L E++
Sbjct: 1078 QELKTAKATLE---------------QDSAKKEQQLQERCKALQDIQKEKSLKEKELVNE 1122
Query: 268 QAILDQYPGDLFGRRTLYLDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNILISNWNK 327
++ L + ++ R+ + L + E D + I+Q+ L +
Sbjct: 1123 KSKLAEIE-EIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLEL-----Q 1176
Query: 328 NRKDFIQKAV------LTLTEACATHEMESMLAKDKKKQQELCADLKAKVRQWRAHQEEV 381
+ D ++ AV + + E E + + +K+ +L +++K K + H+E
Sbjct: 1177 GKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENE 1236
Query: 382 ARLEMEISARRREKEEEKEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLE 441
A+L M+I+A E +KK W +++ E+E ++ +
Sbjct: 1237 AKLTMQITALN--------------------ENLGTVKKEWQSSQRRVSELE----KQTD 1272
Query: 442 ELKKLIAEQSLKDRERVKYRQELLERRLMEKKEVALQEAHEDKERARRLEALRK 495
+L+ IA + R+ LLER L + E+ +K + + LE RK
Sbjct: 1273 DLRGEIAVLEATVQNNQDERRALLERCLKGEGEI-------EKLQTKVLELQRK 1319
Score = 33.9 bits (76), Expect = 0.43
Identities = 52/253 (20%), Positives = 107/253 (42%), Gaps = 31/253 (12%)
Query: 329 RKDFIQKAVLTLTEACATHEMESMLAKDK-KKQQELCADLKAKVRQWRA----------- 376
+K+ +Q L + E ES KD+ KK Q A +A + Q R+
Sbjct: 227 KKELVQVQTL-MDNMTLERERESEKLKDECKKLQSQYASSEATISQLRSELAKGPQEVAV 285
Query: 377 HQEEVARLEMEISARRREKEEEKEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRD 436
+ +E+ +L+ ++ ++ + E L KK++ + E+K + K Q + D
Sbjct: 286 YVQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLD 345
Query: 437 LQRLE--------ELKKLIAEQSLKDRERVKYRQELLERRLMEKKEVALQEAHEDKERAR 488
Q+L+ L ++ E S K K ++EL E E Q + ++ +
Sbjct: 346 CQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSE------VETKYQHLKAEFKQLQ 399
Query: 489 RLEALRKQVAVVAQFDPVRMMSDTMASKARMGIEIEEEFILQKPLFTLNTYNEQQIISDP 548
+ ++Q + Q + ++ S + ++ ++G E Q+ L + +++Q ++D
Sbjct: 400 QQREEKEQHGLQLQSEINQLHSKLLETERQLG-EAHGRLKEQRQLSSEKLMDKEQQVADL 458
Query: 549 RL---RFELALRE 558
+L R E L+E
Sbjct: 459 QLKLSRLEEQLKE 471
Score = 30.8 bits (68), Expect = 3.7
Identities = 53/273 (19%), Positives = 118/273 (43%), Gaps = 30/273 (10%)
Query: 303 EHEKYCDQYRFAIEQQNI----LISNWNKNRKDFIQKAVLTLTEACATHEMESMLAKDKK 358
E +K ++Y+ ++QQ L+++ + + Q+ TE +M+ + +
Sbjct: 108 ELKKELEKYQ-GLQQQEAKPDGLVTDSSAELQSLEQQLEEAQTENFNIKQMKDLFEQKAA 166
Query: 359 KQQELCADLKAKVRQWR----AHQEEVARLEMEISARRREKEEEKEKLWKKKELLQRAEK 414
+ AD+K+K + R A +++V RL E++ ++ K +L ++ + A
Sbjct: 167 QLATEIADIKSKYDEERSLREAAEQKVTRLTEELNKEATVIQDLKTELLQRPGIEDVAVL 226
Query: 415 KKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQELLERRLMEKKE 474
KK++ + E E + +E KKL ++ + + + R EL + +E
Sbjct: 227 KKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASSEATISQLRSELAK----GPQE 282
Query: 475 VALQEAHEDKERARRLEALRKQVAVVAQFDPVRMMSDTMASKARMGIEIE----EEFILQ 530
VA+ + L+ L+ V + Q + + +++ + K + ++E EE + +
Sbjct: 283 VAVY--------VQELQKLKSSVNELTQKN--QTLTENLLKKEQDYTKLEEKHNEESVSK 332
Query: 531 KPLFTLNTYNEQQIISDPRLRFELALREAGLHR 563
K + Q+ + +L+ L+ E LHR
Sbjct: 333 K---NIQATLHQKDLDCQQLQSRLSASETSLHR 362
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 62.0 bits (149), Expect = 1e-09
Identities = 114/536 (21%), Positives = 237/536 (44%), Gaps = 71/536 (13%)
Query: 17 NEMRNIKYKPVDYQQLRALTEAKKLASASAKLKIR-KAMLTSKLSKEQTLIKQHKQVWWQ 75
+EM+++ + D Q+L+ + L S S +LK K ++ L E+ L H + Q
Sbjct: 1435 DEMKSVAKEKDDLQRLQEV-----LQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQ 1489
Query: 76 EYQRLNEVRCKM---ESEIKSLLNEENIGNECLCDLTNFEQELSEQQCTYLKNVINPIQQ 132
E + +NE+R + E+EI ++ + N+ L N QE+ E++ + I+ +Q+
Sbjct: 1490 E-ETINELRVNLSEKETEISTIQKQLEAIND---KLQNKIQEIYEKEEQFNIKQISEVQE 1545
Query: 133 LRADLK-YRQHHTLQHSH-PHIEFNSMKVL-------EEVDFV---KKQLKTVFERLRLE 180
+LK +++H + S IE +++ EE+ + K+++K V E L++E
Sbjct: 1546 KVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIE 1605
Query: 181 QQRIENDLSDWSIKILDHSLEE-------KTNPLSELPIELESLECPYPDLK---SSILS 230
+ +++ + + K+ + +E N E E+E L+ + K +I +
Sbjct: 1606 RDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIET 1665
Query: 231 EFYKFTQKYQKKLQDFNLQLEDIYRNCQLSEEDHWIYQAILDQYPGDLFGRRTLYLDMLQ 290
E + TQ + L++ ++ R+ S E+ + DQ +L R T+ D+ +
Sbjct: 1666 ENIRLTQILHENLEEMRSVTKE--RDDLRSVEE--TLKVERDQLKENL--RETITRDLEK 1719
Query: 291 RYFPHKSRHDLVEHEKYCDQYRFAIEQQNILISNWNKNRKDFIQKAVLTLTEACATHEME 350
+ L EH++ D+ R + ++ ISN K+ + H +
Sbjct: 1720 QEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLE----------------HSND 1763
Query: 351 SMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKLWKKKELLQ 410
++ A+D K Q+EL + + QE + +L +S + + ++ L LQ
Sbjct: 1764 ALKAQDLKIQEEL----RIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQ 1819
Query: 411 RAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQELLERRLM 470
++ K ++ +K + + +E+LKK I +QSL +++ L ++L
Sbjct: 1820 EKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSL-TLSKLEIENLNLAQKLH 1878
Query: 471 EKKEVALQEAHEDKERARRLEALRKQVAVVAQFDPVRMMSDTMASKARMGIEIEEE 526
E E ++ ++++ RR+E K + ++ +KAR +EI++E
Sbjct: 1879 ENLE-EMKSVMKERDNLRRVEETLK-------LERDQLKESLQETKAR-DLEIQQE 1925
Score = 59.7 bits (143), Expect = 7e-09
Identities = 101/435 (23%), Positives = 193/435 (44%), Gaps = 76/435 (17%)
Query: 75 QEYQRLNEVRCKMESEIKSLLNEENIGNECL----CDLTNFEQELSEQQCTYLKNVINPI 130
Q+Y+ + E +M EI +L E + L +L+ QEL E+ ++ +N +
Sbjct: 831 QKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKT-REVQERLNEM 889
Query: 131 QQLRADLKYRQH--HTLQHSHPHIEFNSMKVLEEVDFV---KKQLKTVFERLRLEQQRIE 185
+QL+ L+ R T++ I + LEEV + K LK + E L++E+ +++
Sbjct: 890 EQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLK 949
Query: 186 NDLSDWSIKILDHSLEEKTNPLSELPIELESLECPYPDLKSSILSEFYKFTQKYQKKLQD 245
+D+ D ++ + + E+ N L L E++ LKS I E +
Sbjct: 950 SDIHD-TVNMNIDTQEQLRNALESLKQHQETINT----LKSKISEEVSR----------- 993
Query: 246 FNLQLEDIYRNCQLSEEDHWIYQAILDQYPGDLFGRRTLYLDMLQRYFPHKSRHDLVEHE 305
NL +E+ N ++++ +D+ DL + T L D+ ++E
Sbjct: 994 -NLHMEE---NTGETKDEFQQKMVGIDKKQ-DLEAKNTQTLTA-----------DVKDNE 1037
Query: 306 KYCDQYRFAIEQQNILISNWNKNRKDFIQKAVLTLTEACATHEMESMLAKDKKKQQELCA 365
IEQQ + S IQ+ +E++ ML ++++L
Sbjct: 1038 --------IIEQQRKIFS--------LIQEK----------NELQQMLESVIAEKEQLKT 1071
Query: 366 DLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKLWKKK-ELLQRAEKKKKIKKYWAK 424
DLK + +QEE+ L E+ ++ +EK KK+ EL + ++ ++++ +
Sbjct: 1072 DLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKE 1131
Query: 425 KKQKWQEMEMRDLQRLEEL----KKLIAEQSLKDRERVKYRQELLERRLMEKKEVALQEA 480
K Q+ QE + + L EE+ KK+ ++LK+ +K ++ LE E+ E+A Q+
Sbjct: 1132 KSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKN--ELKNKELTLEHMETERLELA-QKL 1188
Query: 481 HEDKERARRLEALRK 495
+E+ E + + RK
Sbjct: 1189 NENYEEVKSITKERK 1203
Score = 53.1 bits (126), Expect = 7e-07
Identities = 111/547 (20%), Positives = 230/547 (42%), Gaps = 90/547 (16%)
Query: 13 FHMKNEMRNIKYKPVDYQQLRALTEAKKLASASAKLKIRKAMLTSKLSKEQTLIKQHKQV 72
F++K ++ ++ K + +Q + +AK A S + K+ + LT++L + Q I Q+
Sbjct: 1535 FNIK-QISEVQEKVNELKQFKEHRKAKDSALQSIESKMLE--LTNRLQESQEEI----QI 1587
Query: 73 WWQEYQRLNEVRCKMESEIKSLLNEENIGNECLCDLTNFEQELSEQQCTYLK-NVINPIQ 131
+E + + V+ ++ E L E ++ +E E++ +LK +N Q
Sbjct: 1588 MIKEKEEMKRVQEALQIERDQL-------KENTKEIVAKMKESQEKEYQFLKMTAVNETQ 1640
Query: 132 QLRADLKY--RQHHTLQHSHPHIEFNSMKV-------LEEVDFVKKQ---LKTVFERLRL 179
+ ++++ Q T + + +IE ++++ LEE+ V K+ L++V E L++
Sbjct: 1641 EKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKV 1700
Query: 180 EQQRIENDLSDWSIKILDHSLEEKTNPLSELPIELESLECPYPDLKSSILSEFYKFTQKY 239
E+ +++ +L + + L EK L + + L+ + L+ I+SE
Sbjct: 1701 ERDQLKENLRETITRDL-----EKQEELKIVHMHLKEHQETIDKLRG-IVSEKTNEISNM 1754
Query: 240 QK---------KLQDFNLQLEDIYRNCQLSEEDHWIYQAILDQYPGDLFGRRTLYLDMLQ 290
QK K QD +Q E + L E+ Q +D+ G + +T L +Q
Sbjct: 1755 QKDLEHSNDALKAQDLKIQEELRIAHMHLKEQ-----QETIDKLRG-IVSEKTDKLSNMQ 1808
Query: 291 RYFPHKS-------------RHDLVEHEK----------YCDQYRFAIEQQNILISNWNK 327
+ + + H L+ +K +Q + I+ Q++ +S
Sbjct: 1809 KDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEI 1868
Query: 328 NRKDFIQKAVLTLTEACAT------------------HEMESMLAKDKKKQQELCADLKA 369
+ QK L E + +++ L + K + E+ +LK
Sbjct: 1869 ENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKT 1928
Query: 370 KVRQWRAHQEEVARLEMEISARRREKEEEKEKLWKKKELLQRAEKKKKIKKYWAKKKQKW 429
+ H+E V +L +IS + + + ++ L K K+ LQ+ ++ + K+ + ++
Sbjct: 1929 ARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKED 1988
Query: 430 QEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQELLERRLMEKKEVALQEAHEDKERARR 489
M + + +E+LKK Q+L + V+ L ++L E E A E E R
Sbjct: 1989 VNMSHKKINEMEQLKKQFEAQNL-SMQSVRMDNFQLTKKLHESLEEIRIVAKERDELRRI 2047
Query: 490 LEALRKQ 496
E+L+ +
Sbjct: 2048 KESLKME 2054
Score = 52.0 bits (123), Expect = 2e-06
Identities = 99/543 (18%), Positives = 231/543 (42%), Gaps = 63/543 (11%)
Query: 14 HMKNEMRNIKYK-PVDYQQLRALTEAKKLASASAKL----------KIRKAMLTSKLSKE 62
HM+ E + K +Y++++++T+ +K+ K IR+ T +KE
Sbjct: 1176 HMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKE 1235
Query: 63 QTLIKQHKQVWWQEYQR-LNEVRCKMESEIKSLLNEENIGNECL-----CDLTNFEQEL- 115
+ I + +E+Q ++E+R + + ++N +++ + + EQEL
Sbjct: 1236 ELKIAH---IHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELL 1292
Query: 116 -SEQQCTYLKNVINPIQQLRADLKYRQHHTLQHSHPHIEFNSMKV-------LEEVDFVK 167
+ ++ + + +N ++ L + TL IE +++ EE+ +
Sbjct: 1293 PNVKEVSETQETMNELELLTEQSTTKDSTTLAR----IEMERLRLNEKFQESQEEIKSLT 1348
Query: 168 KQ---LKTVFERLRLEQQRIENDLSDWSIKILDH--------SLEEKTNPLSELPIELES 216
K+ LKT+ E L ++ +++ + + KI + +++EK N +++ E+E
Sbjct: 1349 KERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQ 1408
Query: 217 LECPYPDLKSSILSEFYKFTQKYQKKLQDFNLQLEDIYRNCQLSEEDHWIYQAILDQYPG 276
+ K S L K+LQ+ + +++ + + + + Q+ DQ
Sbjct: 1409 FKP-----KDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKE 1463
Query: 277 DLFGRRTLYLDMLQRYFPHKSRHD-LVEHEKYCDQYRFAIEQQNILISNWNKNRKDFIQK 335
++ + + L+ K H L E E+ ++ R + ++ IS K + K
Sbjct: 1464 NI---KEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDK 1520
Query: 336 AVLTLTEACATHEMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLE---MEISARR 392
+ E E ++ K + QE +LK +A + +E +E++ R
Sbjct: 1521 LQNKIQEIYEKEEQFNI--KQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRL 1578
Query: 393 REKEEEKEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEE--LKKLIAEQ 450
+E +EE + + K+KE ++R ++ +I++ K+ K +M++ Q E LK +
Sbjct: 1579 QESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNE 1638
Query: 451 SLKDRERVKYRQELLERRLMEKKEVALQEAHEDKERARRLEALRKQVAVVAQFDPVRMMS 510
+ + +++ +E E + + + + + + LE +R +V + D +R +
Sbjct: 1639 TQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMR---SVTKERDDLRSVE 1695
Query: 511 DTM 513
+T+
Sbjct: 1696 ETL 1698
Score = 47.4 bits (111), Expect = 4e-05
Identities = 104/467 (22%), Positives = 185/467 (39%), Gaps = 66/467 (14%)
Query: 27 VDYQQLRALTEAKKLASASAKLKIRKAMLTSKLSKEQTLIKQHKQVWWQEYQRLNEVRCK 86
+DY+QLR E +L KLK + + L + + L ++ K+ QE Q ++E+
Sbjct: 512 LDYEQLRTEKEEMEL-----KLKEK-----NDLDEFEALERKTKKD--QEMQLIHEI--- 556
Query: 87 MESEIKSLLNEENIGNECLCDLTNFEQEL---SEQQCTYLKNVINP--IQQLRADLKY-- 139
S +K+L+ + N+ L + + + EL E Q L+ I+ ++ ++ DL Y
Sbjct: 557 --SNLKNLVKHAEVYNQDLENELSSKVELLREKEDQIKKLQEYIDSQKLENIKMDLSYSL 614
Query: 140 ---RQHHTLQHSHPHIEFNSMKVLEEVDFVKKQ---LKTVFERLRLEQQRIENDLSDWSI 193
++ + E ++ E F++ + LK + L +++END I
Sbjct: 615 ESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLELKEKMKELATTYKQMEND-----I 669
Query: 194 KILDHSLEEKTNPLSELPIELESLECPYPDLKSSILSEFYK---FTQKYQKKLQDFNLQL 250
++ LE K +L EL+S L S I + K + + K+ D +L
Sbjct: 670 QLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKITDLQKEL 729
Query: 251 -EDIYRNCQLSEEDHWIYQAILDQYPGDLFGRRTLYLDMLQRYFPHKSRHDLVEHEKYCD 309
+++ N L EE I + L P ++ R D + S D + E
Sbjct: 730 NKEVEENEALREEV--ILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHK 787
Query: 310 QYR--------------FAIEQQNIL-----ISNWNKNRKDFIQKAVLTLTEACATHEME 350
+ R A Q N N+ DF QK + L E M
Sbjct: 788 ESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEE---NERMN 844
Query: 351 SMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKLWKKKELLQ 410
+ K+ Q+ + L A + +E+ E+ R E E+ KE+L + LQ
Sbjct: 845 QEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQ 904
Query: 411 RAEKKKKI---KKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKD 454
E++K + K ++ K E DL++L+E ++ +Q D
Sbjct: 905 TVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSD 951
Score = 38.1 bits (87), Expect = 0.023
Identities = 81/443 (18%), Positives = 190/443 (42%), Gaps = 65/443 (14%)
Query: 18 EMRNIKYKPVDYQQLRALTEAKKLASASAKLKIRKAMLTSKLSKEQTL--IKQHKQVWWQ 75
EMR++ + D LR++ E K+ K +R+ +T L K++ L + H + +
Sbjct: 1680 EMRSVTKERDD---LRSVEETLKVERDQLKENLRET-ITRDLEKQEELKIVHMHLKEHQE 1735
Query: 76 EYQRLNEVRCKMESEIKSLLNEENIGNECLC--------DLTNFEQELSEQQCTY----- 122
+L + + +EI ++ + N+ L +L L EQQ T
Sbjct: 1736 TIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRG 1795
Query: 123 --------LKNVINPIQQLRADLKYRQHHTLQHSHPHIEFN-----SMKVLEEVDFVKKQ 169
L N+ ++ A L+ + + H I + K + E++ +KKQ
Sbjct: 1796 IVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQ 1855
Query: 170 LKT---VFERLRLEQ----QRIENDLSDW--------SIKILDHSLEEKTNPLSELPIEL 214
+K +L +E Q++ +L + +++ ++ +L+ + + L E E
Sbjct: 1856 IKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQET 1915
Query: 215 ESLECPYP-DLKSS-ILSEFYKFT-QKYQKKLQDFNLQLEDIYRNCQLSEEDHWIYQAIL 271
++ + +LK++ +LS+ +K T K ++K+ + +Q+ DI ++ S+++ L
Sbjct: 1916 KARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDE-------L 1968
Query: 272 DQYPGDLFGRRTLYLDMLQRY-FPHKSRHDLVEHEKYCDQYRFAIEQQNILISNWNKNRK 330
+ +L + L + + HK +++ + +K + ++ Q++ + N+ +K
Sbjct: 1969 QKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLKKQFEAQNLSM--QSVRMDNFQLTKK 2026
Query: 331 --DFIQKAVLTLTEACATHEMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEI 388
+ +++ + E ++ L K ++ + A L+ + + R + + +
Sbjct: 2027 LHESLEEIRIVAKERDELRRIKESL---KMERDQFIATLREMIARDRQNHQVKPEKRLLS 2083
Query: 389 SARRREKEEEKEKLWKKKELLQR 411
++ E +EK + KELL+R
Sbjct: 2084 DGQQHLTESLREKCSRIKELLKR 2106
Score = 31.6 bits (70), Expect = 2.1
Identities = 34/156 (21%), Positives = 72/156 (46%), Gaps = 30/156 (19%)
Query: 384 LEMEISARRREKEEEKEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEEL 443
L ++ R EKEE + KL +K +L + ++K KK + EM+ + + L
Sbjct: 510 LVLDYEQLRTEKEEMELKLKEKNDLDEFEALERKTKK----------DQEMQLIHEISNL 559
Query: 444 KKLIAE----------------QSLKDRE-RVKYRQELLERRLMEKKEVALQ---EAHED 483
K L+ + L+++E ++K QE ++ + +E ++ L E+ ED
Sbjct: 560 KNLVKHAEVYNQDLENELSSKVELLREKEDQIKKLQEYIDSQKLENIKMDLSYSLESIED 619
Query: 484 KERARRLEALRKQVAVVAQFDPVRMMSDTMASKARM 519
++ ++ + VA+ A+ + + S+ + K +M
Sbjct: 620 PKQMKQTLFDAETVALDAKRESAFLRSENLELKEKM 655
>gi|109134347 NY-REN-58 antigen [Homo sapiens]
Length = 701
Score = 62.0 bits (149), Expect = 1e-09
Identities = 126/562 (22%), Positives = 232/562 (41%), Gaps = 91/562 (16%)
Query: 57 SKLSKEQTLIKQHKQVWWQEYQR-LNEVRCKMESEIKSLLNE-ENIGNECL-CDLTNFEQ 113
+KL E T +K + +EY R L+E + K ESEI L + E + N+ L DLT +
Sbjct: 149 NKLRYEHTFLKSEFEHQKEEYARILDEGKIKYESEIARLEEDKEELRNQLLNVDLTKDSK 208
Query: 114 ELSE--QQCTYLKNVINPIQQLRADLKYRQHHTLQHSHPHIEFNSMKV----LEEVDFVK 167
+ + ++ YL + ++ A+LK + ++S +E N+ ++ L E+
Sbjct: 209 RVEQLAREKVYLCQKLKGLEAEVAELKAEK----ENSEAQVE-NAQRIQVRQLAEMQATV 263
Query: 168 KQLKTVFERLRLEQQRIENDL---SDWSIKILD--HSLEEKTNPLSELPIELE-SLECPY 221
+ L+ + L +R+E +L S+ + +++ H E + N LS EL+ S +
Sbjct: 264 RSLEAEKQSANLRAERLEKELQSSSEQNTFLINKLHKAEREINTLSSKVKELKHSNKLEI 323
Query: 222 PDLK---SSILSEFYKFTQKYQKKLQDFNLQLE------------------DIYRNCQLS 260
D+K + SE + K Q +L E ++ R Q +
Sbjct: 324 TDIKLETARAKSELERERNKIQSELDGLQSDNEILKAAVEHHKVLLVEKDRELIRKVQAA 383
Query: 261 EEDHWIYQAILDQYPGDLFGR----------RTLYLDMLQRYFPHKSRHDLVEHE---KY 307
+E+ + +L +L R ++ + + K R + E K
Sbjct: 384 KEEGYQKLVVLQDEKLELENRLADLEKMKVEHDVWRQSEKDQYEEKLRASQMAEEITRKE 443
Query: 308 CDQYRFAIEQQNILISNWNKNRK---DFIQKAVLTLTEACATHEMESMLAKDKKKQQELC 364
R ++QQ + I N K + D Q+ + + + E+ L + +E+
Sbjct: 444 LQSVRLKLQQQIVTIENAEKEKNENSDLKQQISSLQIQVTSLAQSENDLLNSNQMLKEMV 503
Query: 365 ADLKAKVRQWRAHQEEVARLEMEISARRREKE--EEKEKLWKK-----------KELLQR 411
LK + R +R+ Q E A+LE E + ++ + EEK KL ++ KE LQR
Sbjct: 504 ERLKQECRNFRS-QAEKAQLEAEKTLEEKQIQWLEEKHKLHERITDREEKYNQAKEKLQR 562
Query: 412 AEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQ-ELLERRLM 470
A +K +K + K K + ++ L+ +E +L E + +R+ V + L++RL
Sbjct: 563 AAIAQKKRKSLHENKLKRLQEKVEVLEAKKE--ELETENQVLNRQNVPFEDYTRLQKRLK 620
Query: 471 EKKEVALQEAHEDKERARRLEALRKQVAVVAQFDPVRMMSDTMASKARMGI--EIEEE-- 526
+ +Q H + R L + A +PV S M + ++EE
Sbjct: 621 D-----IQRRHNE----FRSLILVPNMPPTASINPVSFQSSAMVPSMELPFPPHMQEEQH 671
Query: 527 ----FILQKPLFTLNTYNEQQI 544
+L+K L L T +Q+
Sbjct: 672 QRELSLLRKRLEELETTQRKQL 693
Score = 46.2 bits (108), Expect = 8e-05
Identities = 103/512 (20%), Positives = 204/512 (39%), Gaps = 90/512 (17%)
Query: 49 KIRKAMLTSKLSKEQTLIKQHKQVWWQEYQRLNEVRCKMESEIKSLLNEENIGNECLCDL 108
+ +K ++ +L E K + Q E+ RL K+++E+K L NE+ E L
Sbjct: 30 EFQKMLIDERLRCEHH--KANYQTLKAEHTRLQNEHVKLQNELKHLFNEKQTQQEKL--- 84
Query: 109 TNFEQELSEQQCTYLKNVINPIQQLRADLKYRQHHTLQHS--HPHIEFNSMKVLEEVDFV 166
Q L E+ L +++++ + Q L + +E + +D
Sbjct: 85 ----QLLLEELRGELVEKTKDLEEMKLQILTPQKLELLRAQIQQELETPMRERFRNLDEE 140
Query: 167 KKQLKTVFERLRLEQQRIENDLSDWSIKILDHSLEEKTNPLSELPIELESLECPYPDLKS 226
++ + V+ +LR E ++++ +H EE L E I+ ES +
Sbjct: 141 VEKYRAVYNKLRYEHTFLKSE--------FEHQKEEYARILDEGKIKYES--------EI 184
Query: 227 SILSEFYKFTQKYQKKLQDFNLQL-EDIYRNCQLSEEDHWIYQAILDQYPGDLFGRRTLY 285
+ L E K + + Q N+ L +D R QL+ E ++ Q + + L
Sbjct: 185 ARLEE-----DKEELRNQLLNVDLTKDSKRVEQLAREKVYLCQKL-----------KGLE 228
Query: 286 LDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNILISNWNKNRKDFIQKAVLTLTEACA 345
++ + ++ VE+ + + A Q + K + +A E +
Sbjct: 229 AEVAELKAEKENSEAQVENAQRIQVRQLAEMQATVRSLEAEKQSANL--RAERLEKELQS 286
Query: 346 THEMESMLAKDKKKQQELCADLKAKVRQWRAHQE--------EVARLEMEISARRREKEE 397
+ E + L K + L +KV++ + + E AR + E+ R + +
Sbjct: 287 SSEQNTFLINKLHKAEREINTLSSKVKELKHSNKLEITDIKLETARAKSELERERNKIQS 346
Query: 398 EKEKLWKKKELLQRAEKKKK----------IKKYWAKKKQKWQEM-----EMRDLQ-RLE 441
E + L E+L+ A + K I+K A K++ +Q++ E +L+ RL
Sbjct: 347 ELDGLQSDNEILKAAVEHHKVLLVEKDRELIRKVQAAKEEGYQKLVVLQDEKLELENRLA 406
Query: 442 ELKKLIAE-----QSLKDRERVKYRQELLERRLMEKK---------------EVALQEAH 481
+L+K+ E QS KD+ K R + + K+ E A +E +
Sbjct: 407 DLEKMKVEHDVWRQSEKDQYEEKLRASQMAEEITRKELQSVRLKLQQQIVTIENAEKEKN 466
Query: 482 EDKERARRLEALRKQVAVVAQFDPVRMMSDTM 513
E+ + +++ +L+ QV +AQ + + S+ M
Sbjct: 467 ENSDLKQQISSLQIQVTSLAQSENDLLNSNQM 498
>gi|109134355 NY-REN-58 antigen [Homo sapiens]
Length = 701
Score = 62.0 bits (149), Expect = 1e-09
Identities = 126/562 (22%), Positives = 232/562 (41%), Gaps = 91/562 (16%)
Query: 57 SKLSKEQTLIKQHKQVWWQEYQR-LNEVRCKMESEIKSLLNE-ENIGNECL-CDLTNFEQ 113
+KL E T +K + +EY R L+E + K ESEI L + E + N+ L DLT +
Sbjct: 149 NKLRYEHTFLKSEFEHQKEEYARILDEGKIKYESEIARLEEDKEELRNQLLNVDLTKDSK 208
Query: 114 ELSE--QQCTYLKNVINPIQQLRADLKYRQHHTLQHSHPHIEFNSMKV----LEEVDFVK 167
+ + ++ YL + ++ A+LK + ++S +E N+ ++ L E+
Sbjct: 209 RVEQLAREKVYLCQKLKGLEAEVAELKAEK----ENSEAQVE-NAQRIQVRQLAEMQATV 263
Query: 168 KQLKTVFERLRLEQQRIENDL---SDWSIKILD--HSLEEKTNPLSELPIELE-SLECPY 221
+ L+ + L +R+E +L S+ + +++ H E + N LS EL+ S +
Sbjct: 264 RSLEAEKQSANLRAERLEKELQSSSEQNTFLINKLHKAEREINTLSSKVKELKHSNKLEI 323
Query: 222 PDLK---SSILSEFYKFTQKYQKKLQDFNLQLE------------------DIYRNCQLS 260
D+K + SE + K Q +L E ++ R Q +
Sbjct: 324 TDIKLETARAKSELERERNKIQSELDGLQSDNEILKAAVEHHKVLLVEKDRELIRKVQAA 383
Query: 261 EEDHWIYQAILDQYPGDLFGR----------RTLYLDMLQRYFPHKSRHDLVEHE---KY 307
+E+ + +L +L R ++ + + K R + E K
Sbjct: 384 KEEGYQKLVVLQDEKLELENRLADLEKMKVEHDVWRQSEKDQYEEKLRASQMAEEITRKE 443
Query: 308 CDQYRFAIEQQNILISNWNKNRK---DFIQKAVLTLTEACATHEMESMLAKDKKKQQELC 364
R ++QQ + I N K + D Q+ + + + E+ L + +E+
Sbjct: 444 LQSVRLKLQQQIVTIENAEKEKNENSDLKQQISSLQIQVTSLAQSENDLLNSNQMLKEMV 503
Query: 365 ADLKAKVRQWRAHQEEVARLEMEISARRREKE--EEKEKLWKK-----------KELLQR 411
LK + R +R+ Q E A+LE E + ++ + EEK KL ++ KE LQR
Sbjct: 504 ERLKQECRNFRS-QAEKAQLEAEKTLEEKQIQWLEEKHKLHERITDREEKYNQAKEKLQR 562
Query: 412 AEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQ-ELLERRLM 470
A +K +K + K K + ++ L+ +E +L E + +R+ V + L++RL
Sbjct: 563 AAIAQKKRKSLHENKLKRLQEKVEVLEAKKE--ELETENQVLNRQNVPFEDYTRLQKRLK 620
Query: 471 EKKEVALQEAHEDKERARRLEALRKQVAVVAQFDPVRMMSDTMASKARMGI--EIEEE-- 526
+ +Q H + R L + A +PV S M + ++EE
Sbjct: 621 D-----IQRRHNE----FRSLILVPNMPPTASINPVSFQSSAMVPSMELPFPPHMQEEQH 671
Query: 527 ----FILQKPLFTLNTYNEQQI 544
+L+K L L T +Q+
Sbjct: 672 QRELSLLRKRLEELETTQRKQL 693
Score = 46.2 bits (108), Expect = 8e-05
Identities = 103/512 (20%), Positives = 204/512 (39%), Gaps = 90/512 (17%)
Query: 49 KIRKAMLTSKLSKEQTLIKQHKQVWWQEYQRLNEVRCKMESEIKSLLNEENIGNECLCDL 108
+ +K ++ +L E K + Q E+ RL K+++E+K L NE+ E L
Sbjct: 30 EFQKMLIDERLRCEHH--KANYQTLKAEHTRLQNEHVKLQNELKHLFNEKQTQQEKL--- 84
Query: 109 TNFEQELSEQQCTYLKNVINPIQQLRADLKYRQHHTLQHS--HPHIEFNSMKVLEEVDFV 166
Q L E+ L +++++ + Q L + +E + +D
Sbjct: 85 ----QLLLEELRGELVEKTKDLEEMKLQILTPQKLELLRAQIQQELETPMRERFRNLDEE 140
Query: 167 KKQLKTVFERLRLEQQRIENDLSDWSIKILDHSLEEKTNPLSELPIELESLECPYPDLKS 226
++ + V+ +LR E ++++ +H EE L E I+ ES +
Sbjct: 141 VEKYRAVYNKLRYEHTFLKSE--------FEHQKEEYARILDEGKIKYES--------EI 184
Query: 227 SILSEFYKFTQKYQKKLQDFNLQL-EDIYRNCQLSEEDHWIYQAILDQYPGDLFGRRTLY 285
+ L E K + + Q N+ L +D R QL+ E ++ Q + + L
Sbjct: 185 ARLEE-----DKEELRNQLLNVDLTKDSKRVEQLAREKVYLCQKL-----------KGLE 228
Query: 286 LDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNILISNWNKNRKDFIQKAVLTLTEACA 345
++ + ++ VE+ + + A Q + K + +A E +
Sbjct: 229 AEVAELKAEKENSEAQVENAQRIQVRQLAEMQATVRSLEAEKQSANL--RAERLEKELQS 286
Query: 346 THEMESMLAKDKKKQQELCADLKAKVRQWRAHQE--------EVARLEMEISARRREKEE 397
+ E + L K + L +KV++ + + E AR + E+ R + +
Sbjct: 287 SSEQNTFLINKLHKAEREINTLSSKVKELKHSNKLEITDIKLETARAKSELERERNKIQS 346
Query: 398 EKEKLWKKKELLQRAEKKKK----------IKKYWAKKKQKWQEM-----EMRDLQ-RLE 441
E + L E+L+ A + K I+K A K++ +Q++ E +L+ RL
Sbjct: 347 ELDGLQSDNEILKAAVEHHKVLLVEKDRELIRKVQAAKEEGYQKLVVLQDEKLELENRLA 406
Query: 442 ELKKLIAE-----QSLKDRERVKYRQELLERRLMEKK---------------EVALQEAH 481
+L+K+ E QS KD+ K R + + K+ E A +E +
Sbjct: 407 DLEKMKVEHDVWRQSEKDQYEEKLRASQMAEEITRKELQSVRLKLQQQIVTIENAEKEKN 466
Query: 482 EDKERARRLEALRKQVAVVAQFDPVRMMSDTM 513
E+ + +++ +L+ QV +AQ + + S+ M
Sbjct: 467 ENSDLKQQISSLQIQVTSLAQSENDLLNSNQM 498
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 61.6 bits (148), Expect = 2e-09
Identities = 102/481 (21%), Positives = 200/481 (41%), Gaps = 87/481 (18%)
Query: 28 DYQQLRALTEAKKLASASAKLKIRKAMLTSKLS-----KEQTLIKQHKQVW-WQEYQRLN 81
D +++ E +L + + +++ + T S KE+ IK+H+ + E + L
Sbjct: 860 DLLEMKNANEKTRLENQNLLIQVEEVSQTCSKSEIHNEKEKCFIKEHENLKPLLEQKELR 919
Query: 82 EVRCKMESEIKSLLNEENIGNECLCDLTNFEQELS--EQQCTYLKNVINPIQQLRADLKY 139
+ R ++ SL ++ N+ L + E+++ E++C + IN I+ +
Sbjct: 920 DRRAELILLKDSLAKSPSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIKLV------ 973
Query: 140 RQHHTLQHSHPHIEFNSMKVLEEVDFVKKQLKTVFERLRLEQQRIENDLSDWSIKILDHS 199
++K +E+D +K+ +TV E L E R E D S++ L
Sbjct: 974 ----------------AVKAKKELDSSRKETQTVKEEL--ESLRSEKDQLSASMRDLIQG 1015
Query: 200 LEEKTNPLSELPIELESLECPYPDLKSSILSEFYKFTQKYQKKLQDFNLQLEDIYRNCQL 259
E N L E + E L D++ + F + +++D QL + C+
Sbjct: 1016 AESYKNLLLEYEKQSEQL-----DVEKERANNF-------EHRIEDLTRQLRNSTLQCET 1063
Query: 260 SEEDHWIYQAILDQYPGDLFGRRTLYLDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQN 319
D+ D+L R +S L+E + Q A+ +
Sbjct: 1064 INSDNE---------------------DLLARIETLQSNAKLLEVQILEVQRAKAMVDKE 1102
Query: 320 ILISNWNKNRKDFIQKAVLTLTEACATHEMESMLAKDKKKQQELCADLKAKVRQWRAHQE 379
+ K +K I++ T+ E E++ L K+KK+ Q+ +L+ + +
Sbjct: 1103 LEAEKLQKEQK--IKEHATTVNEL---EELQVQLQKEKKQLQKTMQELELVKKD----AQ 1153
Query: 380 EVARLEMEISARRREKEEEKEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQR 439
+ + MEI+ R +E +KL K ++ E++ KI +KQK QE ++
Sbjct: 1154 QTTLMNMEIADYERLMKELNQKLTNKNNKIEDLEQEIKI------QKQK-QETLQEEITS 1206
Query: 440 LEELKKLIAEQSLKDRE-RVKYRQELLERRLMEKKEVALQEAHEDKERARRLEALRKQVA 498
L+ + E++ K ++ VK ++EL + + E + LQ + + + LEA ++QV
Sbjct: 1207 LQSSVQQYEEKNTKIKQLLVKTKKELADSKQAETDHLILQASLKGE-----LEASQQQVE 1261
Query: 499 V 499
V
Sbjct: 1262 V 1262
Score = 40.0 bits (92), Expect = 0.006
Identities = 66/323 (20%), Positives = 128/323 (39%), Gaps = 46/323 (14%)
Query: 153 EFNSMKVLEEVDFVKKQLKTVFERLRLEQQRIEND---LSDWSIKILDHSLEEKTNPLSE 209
E S V E + K L + L LE+ E L +IK + +E+ + +
Sbjct: 57 ELRSKPVTEGTGDIIKALTERLDALLLEKAETEQQCLSLKKENIK-MKQEVEDSVTKMGD 115
Query: 210 LPIELESLECPYPDLKSSILSEFYKFTQKYQKKLQDFNLQLEDIYRNCQLSEEDHWIYQA 269
ELE Y ++ +E KY + + QLE+ N QL +
Sbjct: 116 AHKELEQSHINYVKEIENLKNELMAVRSKYSEDKANLQKQLEEAM-NTQLELSE------ 168
Query: 270 ILDQYPGDLFGRRTLYLDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNILISNWNKNR 329
Q F + S ++ + ++ ++ R E+Q + +
Sbjct: 169 --------------------QLKFQNNSEDNVKKLQEEIEKIRPGFEEQILYLQKQLDAT 208
Query: 330 KDFIQKAVLTLTEACATHEMESMLAKDKKKQQELCADLKAKVRQWRA-HQEEVARLEMEI 388
D ++ V ++++++ + + Q+ L+ ++ Q +A HQEEV L +I
Sbjct: 209 TDEKKETVT---------QLQNIIEANSQHYQKNINSLQEELLQLKAIHQEEVKELMCQI 259
Query: 389 SARRREKEEEKEKLWKKKELL--QRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKL 446
A +E E E KL + KE L Q +K I+K + + + ++ Q + L
Sbjct: 260 EASAKEHEAEINKLNELKENLVKQCEASEKNIQKKYECELENLRKATSNANQDNQICSIL 319
Query: 447 IAEQSLKDR---ERVKYRQELLE 466
+ E + ++ E+VK+ ++ L+
Sbjct: 320 LQENTFVEQVVNEKVKHLEDTLK 342
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 61.2 bits (147), Expect = 3e-09
Identities = 92/466 (19%), Positives = 200/466 (42%), Gaps = 68/466 (14%)
Query: 158 KVLEEVDFVKKQLKTVFERLRLEQQRIENDLSDWSIKILDHSLEEKTNPLSE----LPIE 213
+ L V KK+ E L E+ + +L + I D L+EK L E + E
Sbjct: 179 QALSAVATQKKKADRYIEELTKERDALSLEL--YRNTITDEELKEKNAKLQEKLQLVESE 236
Query: 214 LESLECPYPDLKSSI-LSEFYKFTQKYQKKLQDFNLQLEDIYRNCQLSEEDHWIYQAILD 272
++ +LK + ++ Q+ Q + +L+ + Q E++ ++ L+
Sbjct: 237 KSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNR-LN 295
Query: 273 QYPGDLFGRRTLYLDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNILISNWNKNRKDF 332
Q + R+ + + + + EK +Q Q+ ++ W K K
Sbjct: 296 QQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMM---WEKEEKMR 352
Query: 333 IQKAVLTLTEACATHEMESMLAKDKK--KQQELCADLKAKVR--------QWRAHQEEVA 382
Q+ ++ E + E M K++K +Q+E+ + + K+R Q + ++E
Sbjct: 353 RQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK 412
Query: 383 RLEMEISARRREKEEEKEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEE 442
R E E + +++E++ K+W+++E ++ E+++KI++ ++K+ W++
Sbjct: 413 RQEEEKIREQEKRQEQEAKMWRQEEKIR--EQEEKIRE---QEKKMWRQ----------- 456
Query: 443 LKKLIAEQSLKDRERVKYRQELLERRLMEKKEVALQE----------AHEDKERARRLE- 491
E+ + ++E+++ ++ E+ M ++E + E HE +E+ R+ E
Sbjct: 457 ------EEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEE 510
Query: 492 -ALRKQVAVVAQFDPVRMMSDTM---ASKARMGIEI---EEEFILQKPLFTLNTYNEQQI 544
R++ + Q + +R + M K R E+ EE+ Q+ ++ EQ+
Sbjct: 511 KVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQE- 569
Query: 545 ISDPRLRFELALREAGLHRTLYAKEILPKISPQKPPRKDMESTVFK 590
D R E +RE ++ +E KI Q+ R++ E ++K
Sbjct: 570 --DKMWRQEEKIREQ--EEKVWRQE--EKIREQEEKRQEQEEKMWK 609
Score = 60.5 bits (145), Expect = 4e-09
Identities = 96/510 (18%), Positives = 223/510 (43%), Gaps = 88/510 (17%)
Query: 30 QQLRALTE--AKKLASASAKLK--IRKAMLTSKLSKEQTLIKQHKQVWWQEYQRLNEVRC 85
QQL+A + K+L S SAKL+ + + L ++L+++Q ++ W++ +++ E
Sbjct: 261 QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQ------EEKMWRQEEKIQEWEE 314
Query: 86 KMESEIKSLLNEENIGNECLCDLTNFEQELSEQQCTYLKNVINPIQQLRADLKYRQHHTL 145
K++ + EE I + E+++ EQ+ +++R RQ +
Sbjct: 315 KIQEQ------EEKIREQ--------EEKIREQE-----------EKMR-----RQEEMM 344
Query: 146 QHSHPHIEFNSMKVLEEVDFVKKQLKTVFERLRLEQQRIENDL---SDWSIKILDHSLEE 202
+ + E+ + +++Q + ++E+ E+ R + ++ + I+ L+ + E
Sbjct: 345 WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE--EKMRRQEEMMWEKEEKIRELEEKMHE 402
Query: 203 KTNPLSELPIELESLECPYPDLKSSILSEFYKFTQKYQKKLQDFNLQLEDIYRNCQLSEE 262
+ + E + + + ++ ++ +K +++ + Q + ++R + E
Sbjct: 403 QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHE 462
Query: 263 DHWIYQAILDQYPGDLFGRRTLYLDMLQRYFPHKSRHDLVE-----HEKYCDQYRFAIEQ 317
I + Q +++ + + + + + H+ E EK Q EQ
Sbjct: 463 QEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQ 522
Query: 318 QNILISNWNK--NRKDFIQKAVLTLTEACATHEMESMLAKDKKKQQELCADLKAKVRQWR 375
+ + K +++ I++ E HE E + ++K+++QE + + + R
Sbjct: 523 EEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQE--DKMWRQEEKIR 580
Query: 376 AHQEEVARLEMEISARRREKEEEKEKLWKKKELLQRAEKK-----KKIKKYWAK------ 424
+E+V R E +I + +++E++EK+WK++E ++ E+K +KI++ K
Sbjct: 581 EQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEE 640
Query: 425 ---------------------KKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQE 463
K Q+ +E R +++ E +K I EQ K RE+ + QE
Sbjct: 641 MTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQE 700
Query: 464 LLERRLMEKKEVALQE--AHEDKERARRLE 491
E+ +++++ QE E +E+ RR E
Sbjct: 701 QEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 730
Score = 59.7 bits (143), Expect = 7e-09
Identities = 104/527 (19%), Positives = 230/527 (43%), Gaps = 61/527 (11%)
Query: 39 KKLASASAKLKIRKAMLTSKLSKEQTLIKQHKQVWWQEYQRLNEVRCKMESEIKSLLNEE 98
++L +AKL+ + ++ S+ S+ Q +K+ K+ + L + + + E++
Sbjct: 217 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEAD-------- 268
Query: 99 NIGNECLCDLTNFEQELSEQQCTYLKNVINPIQQLRADLKYRQHHTLQHSHPHIEFNSMK 158
++G E + ++ E + + N + Q + + +RQ +Q I+ K
Sbjct: 269 HLGKELQSVSAKLQAQVEENE------LWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEK 322
Query: 159 VLEEVDFVKKQLKTVFERLRLEQQRIENDLSDWSIKILDHSLEEKTNPLSELPIELESLE 218
+ E+ + +++Q + + R E+ E + + + EEK E+ E E
Sbjct: 323 IREQEEKIREQEEKM---RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE-- 377
Query: 219 CPYPDLKSSILSEFYKFTQKYQKKLQDFNLQLEDIYRNCQLSEEDHWIYQAILDQYPGDL 278
K E ++ ++L++ + E I + +E+ I + Q
Sbjct: 378 ------KMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 431
Query: 279 FGRRTLYLDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNILISN-WNKNRKDFIQKAV 337
R+ + + + + + EK +Q + E++ W + K Q+ +
Sbjct: 432 MWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEI 491
Query: 338 LTLTEACATHEMESMLAKDKKK---QQELCADLKAKVRQ-----WRAH-----QEEVARL 384
E HE E + K ++K Q+E + + K+R+ WR QEE+ R
Sbjct: 492 WRQKEKM--HEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWRE 549
Query: 385 EMEISARRREKEEEK-----EKLWKKKELLQRAEKK-----KKIKKYWAKKKQK----W- 429
E ++ + + EEEK +K+W+++E ++ E+K +KI++ K++++ W
Sbjct: 550 EEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWK 609
Query: 430 QEMEMRDL-QRLEELKKLIAEQSLKDRERVKYRQELLERRLMEKKEVALQE---AHEDKE 485
QE ++R+ ++++E ++ I EQ K RE+ + QE E+ +++++ QE +++
Sbjct: 610 QEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEET 669
Query: 486 RARRLEALRKQVAVV-AQFDPVRMMSDTMASKARMGIEIEEEFILQK 531
R+ E +R+Q + Q + +R + M + E EE+ Q+
Sbjct: 670 MWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQE 716
Score = 55.1 bits (131), Expect = 2e-07
Identities = 81/471 (17%), Positives = 203/471 (43%), Gaps = 56/471 (11%)
Query: 27 VDYQQLRALTEAKKLASASAKLKIRKAMLTSKLSKEQTLIKQHKQVWWQEYQRLNEVRCK 86
+ Q+ + + +K+ K++ ++ M+ K E+ + +Q + +W +E + +
Sbjct: 316 IQEQEEKIREQEEKIREQEEKMRRQEEMMWEK---EEKMRRQEEMMWEKEEKMRRQEEMM 372
Query: 87 MESEIKSLLNEENIGNECLCDLTNFEQELSEQQCTYLKNVINPIQQLRADLKYRQHHTLQ 146
E E K EE + E + E+++ EQ+ + ++ + + K R+ Q
Sbjct: 373 WEKEEKMRRQEEMMW-EKEEKIRELEEKMHEQE-----KIREQEEKRQEEEKIREQEKRQ 426
Query: 147 HSHPHIEFNSMKVLEEVDFVKKQLKTVF---------ERLRLEQQRIENDLSDWSIKILD 197
+ K+ E+ + +++Q K ++ E++R E++R E + W +
Sbjct: 427 EQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQE-EMWRQEEKI 485
Query: 198 HSLEE---KTNPLSELPIELESLECPYPDLKSSILSEFYKFTQKYQK--KLQDFNLQLED 252
H EE + + E ++ E + I + K ++ +K + ++ + E+
Sbjct: 486 HEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEE 545
Query: 253 IYRNCQLSEEDHWIYQAILDQYPGDLFGRRTLYLDMLQRYFPHKSRHDLVEHEKYCDQYR 312
++R + E I++ Q D R+ + + + EK +Q
Sbjct: 546 MWREEEKMHEQEKIWEEEKRQEQEDKMWRQ-------EEKIREQEEKVWRQEEKIREQEE 598
Query: 313 FAIEQQNILISNWNKNRKDFIQKAVLTLTEACATHEMESMLAKDKKKQQELCADLKAKVR 372
EQ+ + W + K E E + + ++K +E ++ +
Sbjct: 599 KRQEQEEKM---WKQEEK---------------IREQEEKIQEQEEKIREQEEKIREQEE 640
Query: 373 QWRAHQEEVARLEMEISARRREKEEEKEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEM 432
+ +E++ E ++ + + +E++E +W+++E ++ E++KKI++ K +++ + M
Sbjct: 641 MTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIR--EQEKKIREQEEKIREQEEMM 698
Query: 433 EMRDLQRLEELKKLI-AEQSLKDRERVKYRQELLERRLMEKKEVALQEAHE 482
+ ++ + E+ +K+ E+ ++++E RQE M ++EV L++ E
Sbjct: 699 QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE----EKMWEQEVRLRQQEE 745
Score = 34.3 bits (77), Expect = 0.33
Identities = 72/395 (18%), Positives = 159/395 (40%), Gaps = 68/395 (17%)
Query: 49 KIRKAMLTSKLSKEQTLIKQHKQVWWQEYQRLNEVRCKMESEIKSLLNEENIGNECLCDL 108
KIR+ L K+ +++ + +Q ++ QE +++ E + E E K EE I +
Sbjct: 392 KIRE--LEEKMHEQEKIREQEEKR--QEEEKIREQEKRQEQEAKMWRQEEKIREQ----- 442
Query: 109 TNFEQELSEQQCTYLKNV--INPIQQLRADLKYRQHHTLQ------HSHPHIEFNSMKVL 160
E+++ EQ+ + I+ +++R + K ++ + H I K+
Sbjct: 443 ---EEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMH 499
Query: 161 EEVDFVKKQLKTVF---ERLRLEQQRI-ENDLSDWSIKILDHSLEEKTNPLSELPIELES 216
E+ + ++KQ + V+ E++R ++++I E + W EEK E+ E E
Sbjct: 500 EQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWR-------QEEKIREQEEMWREEEK 552
Query: 217 LECPYPDLKSSILSEFYKFTQKYQKKLQDFNLQLEDIYRN----------CQLSEEDHWI 266
+ + E + ++K+++ Q E ++R Q EE W
Sbjct: 553 MHEQEKIWEEEKRQEQEDKMWRQEEKIRE---QEEKVWRQEEKIREQEEKRQEQEEKMWK 609
Query: 267 YQAILDQYPGDLFGRRTLYLDMLQRYFPHKSRHDLVEH------EKYCDQYRFAIEQQNI 320
+ + + + + + ++ + E EK C+Q EQ+
Sbjct: 610 QEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEET 669
Query: 321 LISNWNKNRKDFIQKAVLTLTEACATHEMESMLAKDKKKQQELCADLKAKVRQWRAHQEE 380
+ W + K Q+ + E E E M+ + ++K E +E+
Sbjct: 670 M---WRQEEKIREQEKKIREQEE-KIREQEEMMQEQEEKMWE--------------QEEK 711
Query: 381 VARLEMEISARRREKEEEKEKLWKKKELLQRAEKK 415
+ E ++ + + ++EK+W+++ L++ E+K
Sbjct: 712 MCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 746
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 61.2 bits (147), Expect = 3e-09
Identities = 91/468 (19%), Positives = 211/468 (45%), Gaps = 59/468 (12%)
Query: 39 KKLASASAKLKIRKAMLTSKLSKEQTLIKQHKQVWWQEYQRLNEVRCKMESEIKSLLNEE 98
++L +AKL+ + ++ S+ S+ Q +K+ K+ + L + + + E++
Sbjct: 217 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEAD-------- 268
Query: 99 NIGNECLCDLTNFEQELSEQQCTYLKNVINPIQQLRADLKYRQHHTLQHSHPHIEFNSMK 158
++G E + ++ E + + N + Q + + +RQ +Q I+ K
Sbjct: 269 HLGKELQSVSAKLQAQVEENE------LWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEK 322
Query: 159 VLEEVDFVKKQLKTVFERLRLEQQRIENDLSDWSIKILDHSLEEKTNPLSELPIELESLE 218
+ E+ + +++Q E++R +++ + W EEK E+ E E
Sbjct: 323 IREQEEKIREQE----EKMRRQEEMM------WE-------KEEKMRRQEEMMWEKEE-- 363
Query: 219 CPYPDLKSSILSEFYKFTQKYQKKLQDFNLQLEDIYRNCQLSEEDHWIYQAILDQYPGDL 278
K L E ++ ++L++ + E I + +E+ I + Q
Sbjct: 364 ------KMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 417
Query: 279 FGRRTLYLDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNILISN-WNKNRKDFIQKAV 337
R+ + + + + + EK +Q + E++ W + K Q+ +
Sbjct: 418 MWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI 477
Query: 338 LTLTEACATHEMESMLAKDKK--KQQELCADLKAKVRQWRAHQEEVARLEMEISARRREK 395
E HE E + +++K +Q+E D + K+R+ +E++ R E +I + +
Sbjct: 478 WRQKEKM--HEQEKIRKQEEKVWRQEEKMHDQEEKIRE---QEEKMWRQEEKIREQEEKI 532
Query: 396 EEEKEKLWKKKELLQRAEKK--KKIKKYWAKKKQKWQEMEMRDLQ-RLEELKKLIAEQSL 452
E++EK+ +++E++Q E+K ++ +K ++K + QE ++R+ + ++ E K+ I EQ
Sbjct: 533 REQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEE 592
Query: 453 K---DRERVKYRQELL---ERRLMEKKEVALQE---AHEDKERARRLE 491
K E+++ ++E++ E ++ E++E ++ E +E+ RR E
Sbjct: 593 KIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 640
Score = 59.3 bits (142), Expect = 1e-08
Identities = 58/249 (23%), Positives = 115/249 (46%), Gaps = 30/249 (12%)
Query: 303 EHEKYCDQYRFAIEQQNILISNWNKNRKDFIQKAVLTLTEACATHEMESMLAKDKKKQQE 362
E EK +Q E++ I + K Q+A + E + E + ++KK ++
Sbjct: 388 EQEKIREQEEKRQEEEKI-----REQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQ 442
Query: 363 LCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKLWKKKELLQRAEK-KKKIKKY 421
+ K+ + +EE R E E R+ EK E+E++W++KE + EK +K+ +K
Sbjct: 443 -----EEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKV 497
Query: 422 W---------AKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQELLER----- 467
W +K ++ +E R +++ E ++ I EQ K RE+ + QE E+
Sbjct: 498 WRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQE 557
Query: 468 -RLMEKKEVALQE----AHEDKERARRLEALRKQVAVVAQFDPVRMMSDTMASKARMGIE 522
++ E++++ QE E+K R ++ + ++ + Q + +R + M + E
Sbjct: 558 EKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWE 617
Query: 523 IEEEFILQK 531
EE+ Q+
Sbjct: 618 QEEKMCEQE 626
Score = 58.2 bits (139), Expect = 2e-08
Identities = 74/394 (18%), Positives = 166/394 (42%), Gaps = 45/394 (11%)
Query: 158 KVLEEVDFVKKQLKTVFERLRLEQQRIENDLSDWSIKILDHSLEEKTNPLSE----LPIE 213
+ L V KK+ E L E+ + +L + I D L+EK L E + E
Sbjct: 179 QALSAVATQKKKADRYIEELTKERDALSLEL--YRNTITDEELKEKNAKLQEKLQLVESE 236
Query: 214 LESLECPYPDLKSSI-LSEFYKFTQKYQKKLQDFNLQLEDIYRNCQLSEEDHWIYQAILD 272
++ +LK + ++ Q+ Q + +L+ + Q E++ ++ L+
Sbjct: 237 KSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNR-LN 295
Query: 273 QYPGDLFGRRTLYLDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNILISNWNKNRKDF 332
Q + R+ + + + + EK +Q Q+ ++ W K K
Sbjct: 296 QQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMM---WEKEEKMR 352
Query: 333 IQKAVLTLTEACATHEMESMLAKDKK--------------KQQELCADLKAKVRQWRAHQ 378
Q+ ++ E E M K++K ++QE + K+R+ Q
Sbjct: 353 RQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQ 412
Query: 379 EEVARL---EMEISARRREKEEEKEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMR 435
E+ A++ E +I + + E+++K+W+++E + EK ++ +K +++ QE ++R
Sbjct: 413 EQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIR 472
Query: 436 DLQRL-EELKKLIAEQSLKDRERVKYRQELLERRLMEKKEVALQEAHEDKERARRLE--A 492
+ + + + +K+ ++ ++ +E +RQE ++ H+ +E+ R E
Sbjct: 473 EQEEIWRQKEKMHEQEKIRKQEEKVWRQE--------------EKMHDQEEKIREQEEKM 518
Query: 493 LRKQVAVVAQFDPVRMMSDTMASKARMGIEIEEE 526
R++ + Q + +R + + + M E EE+
Sbjct: 519 WRQEEKIREQEEKIREQEEKIREQEEMMQEQEEK 552
Score = 46.6 bits (109), Expect = 6e-05
Identities = 75/436 (17%), Positives = 190/436 (43%), Gaps = 57/436 (13%)
Query: 30 QQLRALTE--AKKLASASAKLK--IRKAMLTSKLSKEQT--LIKQHKQV--WWQEYQRLN 81
QQL+A + K+L S SAKL+ + + L ++L+++Q + +Q +++ W ++ Q
Sbjct: 261 QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE 320
Query: 82 EVRCKMESEIKSLLNEENIGNECLCDLTNFEQELSEQQCTYLKNVINPIQQL--RADLKY 139
E + E +I+ + E + + + E+ + + ++++ + K
Sbjct: 321 EKIREQEEKIREQEEKMRRQEEMMWEKEE-KMRRQEEMMWEKEEKMRRLEEMMWEKEEKI 379
Query: 140 RQHHTLQHSHPHIEFNSMKVLEEVDFVKKQLKTVFERLRLEQQRIENDLSDW----SIKI 195
R+ H I K EE E++R +++R E + W I+
Sbjct: 380 RELEEKMHEQEKIREQEEKRQEE------------EKIREQEKRQEQEAKMWRQEEKIRE 427
Query: 196 LDHSLEEKTNPLSELPIELESLECPYPDLKSSILSEFYKFTQKYQKKLQDFNLQLEDIYR 255
+ + E+ + ++ E + K E ++ +K +++ ++ Q E ++
Sbjct: 428 QEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQ-EEIWRQKEKMHE 486
Query: 256 NCQLSEEDHWIYQAILDQYPGDLFGRRTLYLDMLQRYFPHKSRHDLVEHEKYCDQYRFAI 315
++ +++ +++ Q H + E E+ + I
Sbjct: 487 QEKIRKQEEKVWR---------------------QEEKMHDQEEKIREQEEKMWRQEEKI 525
Query: 316 EQQNILISNWNKNRKDFIQKAVLTLTEACATHEMESMLAKDK-KKQQELCADLKAKVRQW 374
+Q I + ++ Q+ ++ E + E M ++K ++Q+E + + K+R+
Sbjct: 526 REQEEKIREQEEKIRE--QEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQ 583
Query: 375 ----RAHQEEVARLEMEISARRREKEEEKEKLWKKKE-LLQRAEKKKKIKKYWAKKKQKW 429
R +E++ E +I + +E++EK+W+++E + ++ EK ++ ++ ++++K
Sbjct: 584 KEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 643
Query: 430 QEMEMRDLQRLEELKK 445
E E+R Q+ E++++
Sbjct: 644 WEQEVRLRQQEEKMQE 659
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 60.5 bits (145), Expect = 4e-09
Identities = 109/529 (20%), Positives = 218/529 (41%), Gaps = 100/529 (18%)
Query: 16 KNEMRNIKY------KPVDYQQLRALTEAKKLASASAKLKIRKAMLTSKLSKEQTLIKQH 69
K+EM+ ++ K + + ++ E+ K +S + +L+ R+ LT+ L + + + Q
Sbjct: 741 KSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTN-LQENLSEVSQV 799
Query: 70 KQVWWQEYQRLNE-----------VRCKMESEIKSLLNEENIGNECLCDLTNFEQELSEQ 118
K+ +E Q L E V+ M+ + L +E N DL + L++
Sbjct: 800 KETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADM 859
Query: 119 QCTYLKNVINPIQQLRADLKYRQHHTLQHSHPHIEFNSMKVLEEVDFVKKQLKTVFERLR 178
+ + + Q ++A K +E + ++++ QL + + LR
Sbjct: 860 EAKFREKDEREEQLIKAKEK-------------LENDIAEIMKMSGDNSSQLTKMNDELR 906
Query: 179 LEQQRIENDLSDWSIKILDHSLEEKTNPLSELPIELESLECPYPDLKSSILSEFYKFTQK 238
L+++ +E L L + S L +E + + + + ++
Sbjct: 907 LKERDVEE---------LQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKE 957
Query: 239 YQKKLQDFNLQLEDIYRNCQLSEEDHWIYQAILDQYPGDLFGRRTLYLDMLQRYFPHKSR 298
++KL D ++E + CQ + +Y +T + ++LQ +
Sbjct: 958 LERKLSDLEKKMETSHNQCQ----------ELKARYERATSETKTKHEEILQNL-----Q 1002
Query: 299 HDLVEHEKYCDQYRFAIEQQNILISNWNKNRKDFIQKAVLTLTEACATHEMESMLAKDKK 358
L++ E D+ + A E+ + L+ + RK KA T A ME M K
Sbjct: 1003 KTLLDTE---DKLKGAREENSGLLQELEELRKQ-ADKAKAAQTAEDAMQIMEQMT----K 1054
Query: 359 KQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKLWKKKELL----QRAEK 414
++ E A L+ ++ A+L+ E+ + + E+L K KELL Q+ E+
Sbjct: 1055 EKTETLASLEDT-------KQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEE 1107
Query: 415 KKK----IKKYWAKKKQKWQEMEMRDLQRLEEL----KKLIAEQSLKDRERVKYRQELLE 466
+K +K+ A+K Q+ ++ +++ EEL ++ + Q L++ ER +LLE
Sbjct: 1108 FRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEE-ERSVLNNQLLE 1166
Query: 467 RRLMEKKEVALQEAHEDK---------------ERARRLEALRKQVAVV 500
+ E K +++A E+K E+ LE LR +V V+
Sbjct: 1167 MKKRESK--FIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVL 1213
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 60.5 bits (145), Expect = 4e-09
Identities = 109/529 (20%), Positives = 218/529 (41%), Gaps = 100/529 (18%)
Query: 16 KNEMRNIKY------KPVDYQQLRALTEAKKLASASAKLKIRKAMLTSKLSKEQTLIKQH 69
K+EM+ ++ K + + ++ E+ K +S + +L+ R+ LT+ L + + + Q
Sbjct: 776 KSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTN-LQENLSEVSQV 834
Query: 70 KQVWWQEYQRLNE-----------VRCKMESEIKSLLNEENIGNECLCDLTNFEQELSEQ 118
K+ +E Q L E V+ M+ + L +E N DL + L++
Sbjct: 835 KETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADM 894
Query: 119 QCTYLKNVINPIQQLRADLKYRQHHTLQHSHPHIEFNSMKVLEEVDFVKKQLKTVFERLR 178
+ + + Q ++A K +E + ++++ QL + + LR
Sbjct: 895 EAKFREKDEREEQLIKAKEK-------------LENDIAEIMKMSGDNSSQLTKMNDELR 941
Query: 179 LEQQRIENDLSDWSIKILDHSLEEKTNPLSELPIELESLECPYPDLKSSILSEFYKFTQK 238
L+++ +E L L + S L +E + + + + ++
Sbjct: 942 LKERDVEE---------LQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKE 992
Query: 239 YQKKLQDFNLQLEDIYRNCQLSEEDHWIYQAILDQYPGDLFGRRTLYLDMLQRYFPHKSR 298
++KL D ++E + CQ + +Y +T + ++LQ +
Sbjct: 993 LERKLSDLEKKMETSHNQCQ----------ELKARYERATSETKTKHEEILQNL-----Q 1037
Query: 299 HDLVEHEKYCDQYRFAIEQQNILISNWNKNRKDFIQKAVLTLTEACATHEMESMLAKDKK 358
L++ E D+ + A E+ + L+ + RK KA T A ME M K
Sbjct: 1038 KTLLDTE---DKLKGAREENSGLLQELEELRKQ-ADKAKAAQTAEDAMQIMEQMT----K 1089
Query: 359 KQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKLWKKKELL----QRAEK 414
++ E A L+ ++ A+L+ E+ + + E+L K KELL Q+ E+
Sbjct: 1090 EKTETLASLEDT-------KQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEE 1142
Query: 415 KKK----IKKYWAKKKQKWQEMEMRDLQRLEEL----KKLIAEQSLKDRERVKYRQELLE 466
+K +K+ A+K Q+ ++ +++ EEL ++ + Q L++ ER +LLE
Sbjct: 1143 FRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEE-ERSVLNNQLLE 1201
Query: 467 RRLMEKKEVALQEAHEDK---------------ERARRLEALRKQVAVV 500
+ E K +++A E+K E+ LE LR +V V+
Sbjct: 1202 MKKRESK--FIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVL 1248
Score = 40.8 bits (94), Expect = 0.004
Identities = 45/164 (27%), Positives = 80/164 (48%), Gaps = 11/164 (6%)
Query: 330 KDFIQKAVLTLTEACATHEMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEIS 389
+D + V T E E LA+D Q L +L+AK+ Q R E R ++E+
Sbjct: 371 RDLERAEVAKATSHVGEIEQELALARDGHDQHVL--ELEAKMDQLRTMVEAADREKVELL 428
Query: 390 ARRREKEEEKEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAE 449
+ EEEK K+ E LQ +++ I K + + K + +++L++ +K A+
Sbjct: 429 ---NQLEEEKRKV----EDLQFRVEEESITKGDLETQTKLEHARIKELEQSLLFEKTKAD 481
Query: 450 QSLKDRERVKYRQELLERRLME-KKEVALQEAHEDKERARRLEA 492
+ ++ E + + R+ME +K++AL+ E E RRLE+
Sbjct: 482 KLQRELEDTRVATVSEKSRIMELEKDLALR-VQEVAELRRRLES 524
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 60.5 bits (145), Expect = 4e-09
Identities = 97/494 (19%), Positives = 206/494 (41%), Gaps = 45/494 (9%)
Query: 58 KLSKEQTLIKQHKQVWWQEYQRLNEVRCKMESEIKSLLNEENIGNECLCDLTN----FEQ 113
+ KE + Q + Y +L + + +++ E+ L+ + + + + +L F+Q
Sbjct: 1396 RFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQ 1455
Query: 114 ELSEQQCTYLKNVINPI--QQLRADLKYRQHHTLQHSHPHIEFNSMKVLEEVDFVKKQLK 171
L+E+ KN+ + ++ RA+ + R+ T S +++ EE++ K LK
Sbjct: 1456 LLAEE-----KNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLK 1510
Query: 172 TVFERLRLEQQRIENDLSDW--SIKILDHSLEEKTNPLSELPIELES-------LECPYP 222
E L + + ++ + S + L+ +EE L EL EL++ LE
Sbjct: 1511 AEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQ 1570
Query: 223 DLKSSILSEFYKFTQKYQKKLQDFNLQLEDIYRNCQLSEEDHWIYQAILDQYPGDLFGRR 282
LK + ++ ++K + QL + + + + A + GDL
Sbjct: 1571 ALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLE 1630
Query: 283 TLYLDMLQRYFPHKSRHDLVEH-----------EKYCDQYRFAIEQQNILISNWNKNRKD 331
LQ K R + ++ ++ + R A + + N+ +
Sbjct: 1631 ------LQADSAIKGREEAIKQLRKLQAQMKDFQRELEDAR-ASRDEIFATAKENEKKAK 1683
Query: 332 FIQKAVLTLTEACATHEMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEISAR 391
++ ++ L E A E A +K +EL +L + + A Q+E RLE I+
Sbjct: 1684 SLEADLMQLQEDLAAAERARKQADLEK--EELAEELASSLSGRNALQDEKRRLEARIAQL 1741
Query: 392 RREKEEEKEKLWKKKELLQRA-EKKKKIKKYWAKKKQKWQEME--MRDLQRL-EELKKLI 447
E EEE+ + + +++A ++ +++ A ++ Q+ E + L+R +EL+ +
Sbjct: 1742 EEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKL 1801
Query: 448 AEQSLKDRERVKYRQELLERRLMEKKEVALQEAHEDKERARRLEALRKQV-AVVAQFDPV 506
E + + K LE ++ + +E QEA E + + L+ K++ ++ Q +
Sbjct: 1802 HEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDE 1861
Query: 507 RMMSDTMASKARMG 520
R M++ +A G
Sbjct: 1862 RKMAEQYKEQAEKG 1875
Score = 57.8 bits (138), Expect = 3e-08
Identities = 106/529 (20%), Positives = 224/529 (42%), Gaps = 76/529 (14%)
Query: 9 DNLVFHMKNEMR---NIKYKPVDYQQLRA--------LTEAKKLASASAKLKIRKAMLTS 57
D+LV + N+ + N++ K + QL A + + A A A+ K KA+ +
Sbjct: 1430 DDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLA 1489
Query: 58 KLSKEQTLIKQHKQVWWQEYQRLNEVRCKMESEIKSLLNEENIGNECLCDLTNFEQELSE 117
+ +E K+ E +R N++ +++E++ L++ ++ + + +L ++ L E
Sbjct: 1490 RALEEALEAKE-------ELERTNKM---LKAEMEDLVSSKDDVGKNVHELEKSKRAL-E 1538
Query: 118 QQCTYLKNVINPIQ---QLRADLKYRQHHTLQHSHPHIEFNSMKVLEEVDFVKKQLKTVF 174
Q +K + ++ Q D K R +Q E + E+ + ++QL+
Sbjct: 1539 TQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQL 1598
Query: 175 ERLRLE--------------QQRIENDLSDWSIKILDHSL---EEKTNPLSELPIELESL 217
E ++++E DL D ++ D ++ EE L +L +++
Sbjct: 1599 HEYETELEDERKQRALAAAAKKKLEGDLKDLELQA-DSAIKGREEAIKQLRKLQAQMKDF 1657
Query: 218 ECPYPDLKSSILSEFYKFTQKYQKKLQDFNLQL----EDIYRNCQLSEEDHWIYQAILDQ 273
+ D ++S E + ++ +KK + L ED+ + ++ + + ++
Sbjct: 1658 QRELEDARAS-RDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEE 1716
Query: 274 YPGDLFGRRTLY-----LDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNILISNWNKN 328
L GR L L+ + + E D+ R A +Q L SN
Sbjct: 1717 LASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQL-SNELAT 1775
Query: 329 RKDFIQKAVLTLTEACATHEMESMLAKDKKKQQELCADLKAKVRQWRAHQE-EVARLEME 387
+ QK A ++E + + K E+ +K+K + A E ++A+LE +
Sbjct: 1776 ERSTAQK------NESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQ 1829
Query: 388 ISARRREKEEE----KEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEEL 443
+ REK+ K+K K KE+L + E ++K+ + + ++ +K R+++L
Sbjct: 1830 VEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN-------ARVKQL 1882
Query: 444 KKLIAEQSLKDRERVKYRQELLERRL---MEKKEVALQEAHEDKERARR 489
K+ + E++ ++ +R+ + L+R L E E +E + K + RR
Sbjct: 1883 KRQL-EEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRR 1930
Score = 56.6 bits (135), Expect = 6e-08
Identities = 111/576 (19%), Positives = 234/576 (40%), Gaps = 85/576 (14%)
Query: 30 QQLRALTEA-KKLASASAKLKIRKAMLTSKLSKEQTLIKQHKQVWWQEYQRLNEVRCKME 88
Q + LTE ++ A A L K L KE + +V Q Q + + K+E
Sbjct: 1203 QAVEELTEQLEQFKRAKANLDKNK----QTLEKENADLAGELRVLGQAKQEVEHKKKKLE 1258
Query: 89 SEIKSLLNEENIGNECLCDLTNFEQELSEQQCTYLKNVINPIQQLRADLKYRQHHTLQHS 148
++++ L ++ + G +L + +L N ++ + L + ++ +
Sbjct: 1259 AQVQELQSKCSDGERARAELNDKVHKLQ-----------NEVESVTGMLNEAEGKAIKLA 1307
Query: 149 HPHIEFNSM-----KVLEEVDFVKKQLKTVFERLRLEQQRIENDLSDWSIKILDHSLEEK 203
+S ++L+E K + T +L E+ +++ L D +E K
Sbjct: 1308 KDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQL--------DEEMEAK 1359
Query: 204 TN---PLSELPIELESLECPYPDLKSSILSEFYKFTQKYQKKLQDFNLQLEDIYRNCQLS 260
N +S L I+L + D S++ + +++QK++++ Q E+
Sbjct: 1360 QNLERHISTLNIQLSDSKKKLQDFASTV-EALEEGKKRFQKEIENLTQQYEEKAAAYDKL 1418
Query: 261 EEDHWIYQAILDQYPGDLFGRRTLY--LDMLQRYFPHKSRHDLVEHEKYCDQYRFA---- 314
E+ Q LD DL +R L L+ QR F + KY D+ A
Sbjct: 1419 EKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEA 1478
Query: 315 -----------------------IEQQNILISNWNKN---RKDFIQKAV--LTLTEACAT 346
+E+ N ++ ++ KD + K V L ++
Sbjct: 1479 REKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALE 1538
Query: 347 HEMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKLWKKK 406
+ME M + ++ + EL A AK+R Q + E ++ AR + EE++ +L ++
Sbjct: 1539 TQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQL 1598
Query: 407 ELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQELLE 466
+ + ++ ++ A +K E +++DL+ + E+++K +++ + + +
Sbjct: 1599 HEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQ 1658
Query: 467 RRLME---KKEVALQEAHEDKERARRLEALRKQVAVVAQFDPVRMMSD-TMASKARMGIE 522
R L + ++ A E++++A+ LEA D +++ D A +AR +
Sbjct: 1659 RELEDARASRDEIFATAKENEKKAKSLEA-----------DLMQLQEDLAAAERARKQAD 1707
Query: 523 IEEEFILQKPLFTLNTYNEQQIISDPRLRFELALRE 558
+E+E + ++ +L+ N Q D + R E + +
Sbjct: 1708 LEKEELAEELASSLSGRNALQ---DEKRRLEARIAQ 1740
Score = 45.8 bits (107), Expect = 1e-04
Identities = 116/560 (20%), Positives = 239/560 (42%), Gaps = 83/560 (14%)
Query: 57 SKLSKEQTLIKQHKQVWWQEYQRLNEVRCKMESEIKSLLNEENIGNECLCDLTNFE---Q 113
S+L++E+ L+++ Q + Y E+R ++ ++ + L E I +E L E Q
Sbjct: 883 SQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQEL---EEILHEMEARLEEEEDRGQ 939
Query: 114 ELSEQQCTYLKNVINPIQQLRADLKYRQHHTLQHSHPHIEFNSMKVLEEVDFVKKQLKTV 173
+L ++ + +++ +QL + RQ LQ E K+ +E+ + Q
Sbjct: 940 QLQAERKKMAQQMLDLEEQLEEEEAARQK--LQLEKVTAEAKIKKLEDEILVMDDQNN-- 995
Query: 174 FERLRLEQQRIENDLSDWSIKILDHSLEEKTNPLSELPIELESLECPYP-DLKSSILS-- 230
+L E++ +E +SD + + + EEK L++L + ES+ LK S
Sbjct: 996 --KLSKERKLLEERISDLTTNLAEE--EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQ 1051
Query: 231 EFYKFTQKYQKKLQDFNLQLEDIYRNC-----QLSEEDHWIYQAI--LDQYPGDLFGRRT 283
E K +K + DF+ Q+ D+ QL++++ + A+ LD D ++
Sbjct: 1052 ELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLD----DEIAQKN 1107
Query: 284 LYLDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNILISNWNKNRKDFIQKAVLTLTEA 343
L ++ H S DL E ++ + + K ++D ++ TE
Sbjct: 1108 NALKKIRELEGHIS--DLQED----------LDSERAARNKAEKQKRDLGEELEALKTEL 1155
Query: 344 CATHEMESMLAKDK-KKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKL 402
T + + + + K++QE+ KA + R+H+ +V + R+K +
Sbjct: 1156 EDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEM--------RQKHAQ---- 1203
Query: 403 WKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQ 462
+EL ++ E+ K+ K K K Q +E + EL+ L + ++ V++++
Sbjct: 1204 -AVEELTEQLEQFKRAKANLDKNK---QTLEKENADLAGELRVL-----GQAKQEVEHKK 1254
Query: 463 ELLERRLMEKKEVALQEAHEDKERAR-----RLEALRKQVAVV------AQFDPVRMMSD 511
+ LE ++ E LQ D ERAR ++ L+ +V V A+ +++ D
Sbjct: 1255 KKLEAQVQE-----LQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKD 1309
Query: 512 TMASKARMGIEIEEEFILQKPLFTLNTYNEQQIISDPRLRFELAL---REAGLHRTLYAK 568
+ ++ ++ +E + ++ LN + + + + R + L EA + +
Sbjct: 1310 VASLSSQ--LQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHIS 1367
Query: 569 EILPKISPQKPPRKDMESTV 588
+ ++S K +D STV
Sbjct: 1368 TLNIQLSDSKKKLQDFASTV 1387
Score = 43.1 bits (100), Expect = 7e-04
Identities = 47/183 (25%), Positives = 88/183 (48%), Gaps = 21/183 (11%)
Query: 350 ESMLAKDKKKQQELCADLKAKVRQW-RAHQE-----EVARLEMEISARRREKEEEKEKLW 403
+ L K Q+ A LK + QW R + +V R E E+ A+ E ++ KE+
Sbjct: 810 QQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQ 869
Query: 404 KK----KELLQR----AEKKKKIKKYWAKKKQKW---QEMEMRDLQRLEELKKLIAEQSL 452
K KEL Q+ E+K +++ + + + +EM +R + +EL++++ E
Sbjct: 870 KAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEA 929
Query: 453 KDRERVKYRQEL-LERRLMEKKEVALQEAHEDKERAR---RLEALRKQVAVVAQFDPVRM 508
+ E Q+L ER+ M ++ + L+E E++E AR +LE + + + D + +
Sbjct: 930 RLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILV 989
Query: 509 MSD 511
M D
Sbjct: 990 MDD 992
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 60.5 bits (145), Expect = 4e-09
Identities = 97/494 (19%), Positives = 206/494 (41%), Gaps = 45/494 (9%)
Query: 58 KLSKEQTLIKQHKQVWWQEYQRLNEVRCKMESEIKSLLNEENIGNECLCDLTN----FEQ 113
+ KE + Q + Y +L + + +++ E+ L+ + + + + +L F+Q
Sbjct: 1403 RFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQ 1462
Query: 114 ELSEQQCTYLKNVINPI--QQLRADLKYRQHHTLQHSHPHIEFNSMKVLEEVDFVKKQLK 171
L+E+ KN+ + ++ RA+ + R+ T S +++ EE++ K LK
Sbjct: 1463 LLAEE-----KNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLK 1517
Query: 172 TVFERLRLEQQRIENDLSDW--SIKILDHSLEEKTNPLSELPIELES-------LECPYP 222
E L + + ++ + S + L+ +EE L EL EL++ LE
Sbjct: 1518 AEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQ 1577
Query: 223 DLKSSILSEFYKFTQKYQKKLQDFNLQLEDIYRNCQLSEEDHWIYQAILDQYPGDLFGRR 282
LK + ++ ++K + QL + + + + A + GDL
Sbjct: 1578 ALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLE 1637
Query: 283 TLYLDMLQRYFPHKSRHDLVEH-----------EKYCDQYRFAIEQQNILISNWNKNRKD 331
LQ K R + ++ ++ + R A + + N+ +
Sbjct: 1638 ------LQADSAIKGREEAIKQLRKLQAQMKDFQRELEDAR-ASRDEIFATAKENEKKAK 1690
Query: 332 FIQKAVLTLTEACATHEMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEISAR 391
++ ++ L E A E A +K +EL +L + + A Q+E RLE I+
Sbjct: 1691 SLEADLMQLQEDLAAAERARKQADLEK--EELAEELASSLSGRNALQDEKRRLEARIAQL 1748
Query: 392 RREKEEEKEKLWKKKELLQRA-EKKKKIKKYWAKKKQKWQEME--MRDLQRL-EELKKLI 447
E EEE+ + + +++A ++ +++ A ++ Q+ E + L+R +EL+ +
Sbjct: 1749 EEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKL 1808
Query: 448 AEQSLKDRERVKYRQELLERRLMEKKEVALQEAHEDKERARRLEALRKQV-AVVAQFDPV 506
E + + K LE ++ + +E QEA E + + L+ K++ ++ Q +
Sbjct: 1809 HEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDE 1868
Query: 507 RMMSDTMASKARMG 520
R M++ +A G
Sbjct: 1869 RKMAEQYKEQAEKG 1882
Score = 57.8 bits (138), Expect = 3e-08
Identities = 106/529 (20%), Positives = 224/529 (42%), Gaps = 76/529 (14%)
Query: 9 DNLVFHMKNEMR---NIKYKPVDYQQLRA--------LTEAKKLASASAKLKIRKAMLTS 57
D+LV + N+ + N++ K + QL A + + A A A+ K KA+ +
Sbjct: 1437 DDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLA 1496
Query: 58 KLSKEQTLIKQHKQVWWQEYQRLNEVRCKMESEIKSLLNEENIGNECLCDLTNFEQELSE 117
+ +E K+ E +R N++ +++E++ L++ ++ + + +L ++ L E
Sbjct: 1497 RALEEALEAKE-------ELERTNKM---LKAEMEDLVSSKDDVGKNVHELEKSKRAL-E 1545
Query: 118 QQCTYLKNVINPIQ---QLRADLKYRQHHTLQHSHPHIEFNSMKVLEEVDFVKKQLKTVF 174
Q +K + ++ Q D K R +Q E + E+ + ++QL+
Sbjct: 1546 TQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQL 1605
Query: 175 ERLRLE--------------QQRIENDLSDWSIKILDHSL---EEKTNPLSELPIELESL 217
E ++++E DL D ++ D ++ EE L +L +++
Sbjct: 1606 HEYETELEDERKQRALAAAAKKKLEGDLKDLELQA-DSAIKGREEAIKQLRKLQAQMKDF 1664
Query: 218 ECPYPDLKSSILSEFYKFTQKYQKKLQDFNLQL----EDIYRNCQLSEEDHWIYQAILDQ 273
+ D ++S E + ++ +KK + L ED+ + ++ + + ++
Sbjct: 1665 QRELEDARAS-RDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEE 1723
Query: 274 YPGDLFGRRTLY-----LDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNILISNWNKN 328
L GR L L+ + + E D+ R A +Q L SN
Sbjct: 1724 LASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQL-SNELAT 1782
Query: 329 RKDFIQKAVLTLTEACATHEMESMLAKDKKKQQELCADLKAKVRQWRAHQE-EVARLEME 387
+ QK A ++E + + K E+ +K+K + A E ++A+LE +
Sbjct: 1783 ERSTAQK------NESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQ 1836
Query: 388 ISARRREKEEE----KEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEEL 443
+ REK+ K+K K KE+L + E ++K+ + + ++ +K R+++L
Sbjct: 1837 VEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN-------ARVKQL 1889
Query: 444 KKLIAEQSLKDRERVKYRQELLERRL---MEKKEVALQEAHEDKERARR 489
K+ + E++ ++ +R+ + L+R L E E +E + K + RR
Sbjct: 1890 KRQL-EEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRR 1937
Score = 56.6 bits (135), Expect = 6e-08
Identities = 111/576 (19%), Positives = 234/576 (40%), Gaps = 85/576 (14%)
Query: 30 QQLRALTEA-KKLASASAKLKIRKAMLTSKLSKEQTLIKQHKQVWWQEYQRLNEVRCKME 88
Q + LTE ++ A A L K L KE + +V Q Q + + K+E
Sbjct: 1210 QAVEELTEQLEQFKRAKANLDKNK----QTLEKENADLAGELRVLGQAKQEVEHKKKKLE 1265
Query: 89 SEIKSLLNEENIGNECLCDLTNFEQELSEQQCTYLKNVINPIQQLRADLKYRQHHTLQHS 148
++++ L ++ + G +L + +L N ++ + L + ++ +
Sbjct: 1266 AQVQELQSKCSDGERARAELNDKVHKLQ-----------NEVESVTGMLNEAEGKAIKLA 1314
Query: 149 HPHIEFNSM-----KVLEEVDFVKKQLKTVFERLRLEQQRIENDLSDWSIKILDHSLEEK 203
+S ++L+E K + T +L E+ +++ L D +E K
Sbjct: 1315 KDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQL--------DEEMEAK 1366
Query: 204 TN---PLSELPIELESLECPYPDLKSSILSEFYKFTQKYQKKLQDFNLQLEDIYRNCQLS 260
N +S L I+L + D S++ + +++QK++++ Q E+
Sbjct: 1367 QNLERHISTLNIQLSDSKKKLQDFASTV-EALEEGKKRFQKEIENLTQQYEEKAAAYDKL 1425
Query: 261 EEDHWIYQAILDQYPGDLFGRRTLY--LDMLQRYFPHKSRHDLVEHEKYCDQYRFA---- 314
E+ Q LD DL +R L L+ QR F + KY D+ A
Sbjct: 1426 EKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEA 1485
Query: 315 -----------------------IEQQNILISNWNKN---RKDFIQKAV--LTLTEACAT 346
+E+ N ++ ++ KD + K V L ++
Sbjct: 1486 REKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALE 1545
Query: 347 HEMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKLWKKK 406
+ME M + ++ + EL A AK+R Q + E ++ AR + EE++ +L ++
Sbjct: 1546 TQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQL 1605
Query: 407 ELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQELLE 466
+ + ++ ++ A +K E +++DL+ + E+++K +++ + + +
Sbjct: 1606 HEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQ 1665
Query: 467 RRLME---KKEVALQEAHEDKERARRLEALRKQVAVVAQFDPVRMMSD-TMASKARMGIE 522
R L + ++ A E++++A+ LEA D +++ D A +AR +
Sbjct: 1666 RELEDARASRDEIFATAKENEKKAKSLEA-----------DLMQLQEDLAAAERARKQAD 1714
Query: 523 IEEEFILQKPLFTLNTYNEQQIISDPRLRFELALRE 558
+E+E + ++ +L+ N Q D + R E + +
Sbjct: 1715 LEKEELAEELASSLSGRNALQ---DEKRRLEARIAQ 1747
Score = 45.8 bits (107), Expect = 1e-04
Identities = 116/560 (20%), Positives = 239/560 (42%), Gaps = 83/560 (14%)
Query: 57 SKLSKEQTLIKQHKQVWWQEYQRLNEVRCKMESEIKSLLNEENIGNECLCDLTNFE---Q 113
S+L++E+ L+++ Q + Y E+R ++ ++ + L E I +E L E Q
Sbjct: 890 SQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQEL---EEILHEMEARLEEEEDRGQ 946
Query: 114 ELSEQQCTYLKNVINPIQQLRADLKYRQHHTLQHSHPHIEFNSMKVLEEVDFVKKQLKTV 173
+L ++ + +++ +QL + RQ LQ E K+ +E+ + Q
Sbjct: 947 QLQAERKKMAQQMLDLEEQLEEEEAARQK--LQLEKVTAEAKIKKLEDEILVMDDQNN-- 1002
Query: 174 FERLRLEQQRIENDLSDWSIKILDHSLEEKTNPLSELPIELESLECPYP-DLKSSILS-- 230
+L E++ +E +SD + + + EEK L++L + ES+ LK S
Sbjct: 1003 --KLSKERKLLEERISDLTTNLAEE--EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQ 1058
Query: 231 EFYKFTQKYQKKLQDFNLQLEDIYRNC-----QLSEEDHWIYQAI--LDQYPGDLFGRRT 283
E K +K + DF+ Q+ D+ QL++++ + A+ LD D ++
Sbjct: 1059 ELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLD----DEIAQKN 1114
Query: 284 LYLDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNILISNWNKNRKDFIQKAVLTLTEA 343
L ++ H S DL E ++ + + K ++D ++ TE
Sbjct: 1115 NALKKIRELEGHIS--DLQED----------LDSERAARNKAEKQKRDLGEELEALKTEL 1162
Query: 344 CATHEMESMLAKDK-KKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKL 402
T + + + + K++QE+ KA + R+H+ +V + R+K +
Sbjct: 1163 EDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEM--------RQKHAQ---- 1210
Query: 403 WKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQ 462
+EL ++ E+ K+ K K K Q +E + EL+ L + ++ V++++
Sbjct: 1211 -AVEELTEQLEQFKRAKANLDKNK---QTLEKENADLAGELRVL-----GQAKQEVEHKK 1261
Query: 463 ELLERRLMEKKEVALQEAHEDKERAR-----RLEALRKQVAVV------AQFDPVRMMSD 511
+ LE ++ E LQ D ERAR ++ L+ +V V A+ +++ D
Sbjct: 1262 KKLEAQVQE-----LQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKD 1316
Query: 512 TMASKARMGIEIEEEFILQKPLFTLNTYNEQQIISDPRLRFELAL---REAGLHRTLYAK 568
+ ++ ++ +E + ++ LN + + + + R + L EA + +
Sbjct: 1317 VASLSSQ--LQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHIS 1374
Query: 569 EILPKISPQKPPRKDMESTV 588
+ ++S K +D STV
Sbjct: 1375 TLNIQLSDSKKKLQDFASTV 1394
Score = 43.1 bits (100), Expect = 7e-04
Identities = 47/183 (25%), Positives = 88/183 (48%), Gaps = 21/183 (11%)
Query: 350 ESMLAKDKKKQQELCADLKAKVRQW-RAHQE-----EVARLEMEISARRREKEEEKEKLW 403
+ L K Q+ A LK + QW R + +V R E E+ A+ E ++ KE+
Sbjct: 817 QQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQ 876
Query: 404 KK----KELLQR----AEKKKKIKKYWAKKKQKW---QEMEMRDLQRLEELKKLIAEQSL 452
K KEL Q+ E+K +++ + + + +EM +R + +EL++++ E
Sbjct: 877 KAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEA 936
Query: 453 KDRERVKYRQEL-LERRLMEKKEVALQEAHEDKERAR---RLEALRKQVAVVAQFDPVRM 508
+ E Q+L ER+ M ++ + L+E E++E AR +LE + + + D + +
Sbjct: 937 RLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILV 996
Query: 509 MSD 511
M D
Sbjct: 997 MDD 999
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 60.5 bits (145), Expect = 4e-09
Identities = 97/494 (19%), Positives = 206/494 (41%), Gaps = 45/494 (9%)
Query: 58 KLSKEQTLIKQHKQVWWQEYQRLNEVRCKMESEIKSLLNEENIGNECLCDLTN----FEQ 113
+ KE + Q + Y +L + + +++ E+ L+ + + + + +L F+Q
Sbjct: 1403 RFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQ 1462
Query: 114 ELSEQQCTYLKNVINPI--QQLRADLKYRQHHTLQHSHPHIEFNSMKVLEEVDFVKKQLK 171
L+E+ KN+ + ++ RA+ + R+ T S +++ EE++ K LK
Sbjct: 1463 LLAEE-----KNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLK 1517
Query: 172 TVFERLRLEQQRIENDLSDW--SIKILDHSLEEKTNPLSELPIELES-------LECPYP 222
E L + + ++ + S + L+ +EE L EL EL++ LE
Sbjct: 1518 AEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQ 1577
Query: 223 DLKSSILSEFYKFTQKYQKKLQDFNLQLEDIYRNCQLSEEDHWIYQAILDQYPGDLFGRR 282
LK + ++ ++K + QL + + + + A + GDL
Sbjct: 1578 ALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLE 1637
Query: 283 TLYLDMLQRYFPHKSRHDLVEH-----------EKYCDQYRFAIEQQNILISNWNKNRKD 331
LQ K R + ++ ++ + R A + + N+ +
Sbjct: 1638 ------LQADSAIKGREEAIKQLRKLQAQMKDFQRELEDAR-ASRDEIFATAKENEKKAK 1690
Query: 332 FIQKAVLTLTEACATHEMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEISAR 391
++ ++ L E A E A +K +EL +L + + A Q+E RLE I+
Sbjct: 1691 SLEADLMQLQEDLAAAERARKQADLEK--EELAEELASSLSGRNALQDEKRRLEARIAQL 1748
Query: 392 RREKEEEKEKLWKKKELLQRA-EKKKKIKKYWAKKKQKWQEME--MRDLQRL-EELKKLI 447
E EEE+ + + +++A ++ +++ A ++ Q+ E + L+R +EL+ +
Sbjct: 1749 EEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKL 1808
Query: 448 AEQSLKDRERVKYRQELLERRLMEKKEVALQEAHEDKERARRLEALRKQV-AVVAQFDPV 506
E + + K LE ++ + +E QEA E + + L+ K++ ++ Q +
Sbjct: 1809 HEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDE 1868
Query: 507 RMMSDTMASKARMG 520
R M++ +A G
Sbjct: 1869 RKMAEQYKEQAEKG 1882
Score = 56.6 bits (135), Expect = 6e-08
Identities = 111/576 (19%), Positives = 234/576 (40%), Gaps = 85/576 (14%)
Query: 30 QQLRALTEA-KKLASASAKLKIRKAMLTSKLSKEQTLIKQHKQVWWQEYQRLNEVRCKME 88
Q + LTE ++ A A L K L KE + +V Q Q + + K+E
Sbjct: 1210 QAVEELTEQLEQFKRAKANLDKNK----QTLEKENADLAGELRVLGQAKQEVEHKKKKLE 1265
Query: 89 SEIKSLLNEENIGNECLCDLTNFEQELSEQQCTYLKNVINPIQQLRADLKYRQHHTLQHS 148
++++ L ++ + G +L + +L N ++ + L + ++ +
Sbjct: 1266 AQVQELQSKCSDGERARAELNDKVHKLQ-----------NEVESVTGMLNEAEGKAIKLA 1314
Query: 149 HPHIEFNSM-----KVLEEVDFVKKQLKTVFERLRLEQQRIENDLSDWSIKILDHSLEEK 203
+S ++L+E K + T +L E+ +++ L D +E K
Sbjct: 1315 KDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQL--------DEEMEAK 1366
Query: 204 TN---PLSELPIELESLECPYPDLKSSILSEFYKFTQKYQKKLQDFNLQLEDIYRNCQLS 260
N +S L I+L + D S++ + +++QK++++ Q E+
Sbjct: 1367 QNLERHISTLNIQLSDSKKKLQDFASTV-EALEEGKKRFQKEIENLTQQYEEKAAAYDKL 1425
Query: 261 EEDHWIYQAILDQYPGDLFGRRTLY--LDMLQRYFPHKSRHDLVEHEKYCDQYRFA---- 314
E+ Q LD DL +R L L+ QR F + KY D+ A
Sbjct: 1426 EKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEA 1485
Query: 315 -----------------------IEQQNILISNWNKN---RKDFIQKAV--LTLTEACAT 346
+E+ N ++ ++ KD + K V L ++
Sbjct: 1486 REKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALE 1545
Query: 347 HEMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKLWKKK 406
+ME M + ++ + EL A AK+R Q + E ++ AR + EE++ +L ++
Sbjct: 1546 TQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQL 1605
Query: 407 ELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQELLE 466
+ + ++ ++ A +K E +++DL+ + E+++K +++ + + +
Sbjct: 1606 HEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQ 1665
Query: 467 RRLME---KKEVALQEAHEDKERARRLEALRKQVAVVAQFDPVRMMSD-TMASKARMGIE 522
R L + ++ A E++++A+ LEA D +++ D A +AR +
Sbjct: 1666 RELEDARASRDEIFATAKENEKKAKSLEA-----------DLMQLQEDLAAAERARKQAD 1714
Query: 523 IEEEFILQKPLFTLNTYNEQQIISDPRLRFELALRE 558
+E+E + ++ +L+ N Q D + R E + +
Sbjct: 1715 LEKEELAEELASSLSGRNALQ---DEKRRLEARIAQ 1747
Score = 56.6 bits (135), Expect = 6e-08
Identities = 102/511 (19%), Positives = 217/511 (42%), Gaps = 73/511 (14%)
Query: 9 DNLVFHMKNEMR---NIKYKPVDYQQLRA--------LTEAKKLASASAKLKIRKAMLTS 57
D+LV + N+ + N++ K + QL A + + A A A+ K KA+ +
Sbjct: 1437 DDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLA 1496
Query: 58 KLSKEQTLIKQHKQVWWQEYQRLNEVRCKMESEIKSLLNEENIGNECLCDLTNFEQELSE 117
+ +E K+ E +R N++ +++E++ L++ ++ + + +L ++ L E
Sbjct: 1497 RALEEALEAKE-------ELERTNKM---LKAEMEDLVSSKDDVGKNVHELEKSKRAL-E 1545
Query: 118 QQCTYLKNVINPIQ---QLRADLKYRQHHTLQHSHPHIEFNSMKVLEEVDFVKKQLKTVF 174
Q +K + ++ Q D K R +Q E + E+ + ++QL+
Sbjct: 1546 TQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQL 1605
Query: 175 ERLRLE--------------QQRIENDLSDWSIKILDHSL---EEKTNPLSELPIELESL 217
E ++++E DL D ++ D ++ EE L +L +++
Sbjct: 1606 HEYETELEDERKQRALAAAAKKKLEGDLKDLELQA-DSAIKGREEAIKQLRKLQAQMKDF 1664
Query: 218 ECPYPDLKSSILSEFYKFTQKYQKKLQDFNLQL----EDIYRNCQLSEEDHWIYQAILDQ 273
+ D ++S E + ++ +KK + L ED+ + ++ + + ++
Sbjct: 1665 QRELEDARAS-RDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEE 1723
Query: 274 YPGDLFGRRTLY-----LDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNILISNWNKN 328
L GR L L+ + + E D+ R A +Q L SN
Sbjct: 1724 LASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQL-SNELAT 1782
Query: 329 RKDFIQKAVLTLTEACATHEMESMLAKDKKKQQELCADLKAKVRQWRAHQE-EVARLEME 387
+ QK A ++E + + K E+ +K+K + A E ++A+LE +
Sbjct: 1783 ERSTAQK------NESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQ 1836
Query: 388 ISARRREKEEE----KEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEEL 443
+ REK+ K+K K KE+L + E ++K+ + + ++ +K R+++L
Sbjct: 1837 VEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN-------ARVKQL 1889
Query: 444 KKLIAEQSLKDRERVKYRQELLERRLMEKKE 474
K+ + E++ ++ +R+ + L+R L E E
Sbjct: 1890 KRQL-EEAEEESQRINANRRKLQRELDEATE 1919
Score = 45.8 bits (107), Expect = 1e-04
Identities = 116/560 (20%), Positives = 239/560 (42%), Gaps = 83/560 (14%)
Query: 57 SKLSKEQTLIKQHKQVWWQEYQRLNEVRCKMESEIKSLLNEENIGNECLCDLTNFE---Q 113
S+L++E+ L+++ Q + Y E+R ++ ++ + L E I +E L E Q
Sbjct: 890 SQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQEL---EEILHEMEARLEEEEDRGQ 946
Query: 114 ELSEQQCTYLKNVINPIQQLRADLKYRQHHTLQHSHPHIEFNSMKVLEEVDFVKKQLKTV 173
+L ++ + +++ +QL + RQ LQ E K+ +E+ + Q
Sbjct: 947 QLQAERKKMAQQMLDLEEQLEEEEAARQK--LQLEKVTAEAKIKKLEDEILVMDDQNN-- 1002
Query: 174 FERLRLEQQRIENDLSDWSIKILDHSLEEKTNPLSELPIELESLECPYP-DLKSSILS-- 230
+L E++ +E +SD + + + EEK L++L + ES+ LK S
Sbjct: 1003 --KLSKERKLLEERISDLTTNLAEE--EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQ 1058
Query: 231 EFYKFTQKYQKKLQDFNLQLEDIYRNC-----QLSEEDHWIYQAI--LDQYPGDLFGRRT 283
E K +K + DF+ Q+ D+ QL++++ + A+ LD D ++
Sbjct: 1059 ELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLD----DEIAQKN 1114
Query: 284 LYLDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNILISNWNKNRKDFIQKAVLTLTEA 343
L ++ H S DL E ++ + + K ++D ++ TE
Sbjct: 1115 NALKKIRELEGHIS--DLQED----------LDSERAARNKAEKQKRDLGEELEALKTEL 1162
Query: 344 CATHEMESMLAKDK-KKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKL 402
T + + + + K++QE+ KA + R+H+ +V + R+K +
Sbjct: 1163 EDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEM--------RQKHAQ---- 1210
Query: 403 WKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQ 462
+EL ++ E+ K+ K K K Q +E + EL+ L + ++ V++++
Sbjct: 1211 -AVEELTEQLEQFKRAKANLDKNK---QTLEKENADLAGELRVL-----GQAKQEVEHKK 1261
Query: 463 ELLERRLMEKKEVALQEAHEDKERAR-----RLEALRKQVAVV------AQFDPVRMMSD 511
+ LE ++ E LQ D ERAR ++ L+ +V V A+ +++ D
Sbjct: 1262 KKLEAQVQE-----LQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKD 1316
Query: 512 TMASKARMGIEIEEEFILQKPLFTLNTYNEQQIISDPRLRFELAL---REAGLHRTLYAK 568
+ ++ ++ +E + ++ LN + + + + R + L EA + +
Sbjct: 1317 VASLSSQ--LQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHIS 1374
Query: 569 EILPKISPQKPPRKDMESTV 588
+ ++S K +D STV
Sbjct: 1375 TLNIQLSDSKKKLQDFASTV 1394
Score = 43.1 bits (100), Expect = 7e-04
Identities = 47/183 (25%), Positives = 88/183 (48%), Gaps = 21/183 (11%)
Query: 350 ESMLAKDKKKQQELCADLKAKVRQW-RAHQE-----EVARLEMEISARRREKEEEKEKLW 403
+ L K Q+ A LK + QW R + +V R E E+ A+ E ++ KE+
Sbjct: 817 QQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQ 876
Query: 404 KK----KELLQR----AEKKKKIKKYWAKKKQKW---QEMEMRDLQRLEELKKLIAEQSL 452
K KEL Q+ E+K +++ + + + +EM +R + +EL++++ E
Sbjct: 877 KAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEA 936
Query: 453 KDRERVKYRQEL-LERRLMEKKEVALQEAHEDKERAR---RLEALRKQVAVVAQFDPVRM 508
+ E Q+L ER+ M ++ + L+E E++E AR +LE + + + D + +
Sbjct: 937 RLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILV 996
Query: 509 MSD 511
M D
Sbjct: 997 MDD 999
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 60.5 bits (145), Expect = 4e-09
Identities = 97/494 (19%), Positives = 206/494 (41%), Gaps = 45/494 (9%)
Query: 58 KLSKEQTLIKQHKQVWWQEYQRLNEVRCKMESEIKSLLNEENIGNECLCDLTN----FEQ 113
+ KE + Q + Y +L + + +++ E+ L+ + + + + +L F+Q
Sbjct: 1396 RFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQ 1455
Query: 114 ELSEQQCTYLKNVINPI--QQLRADLKYRQHHTLQHSHPHIEFNSMKVLEEVDFVKKQLK 171
L+E+ KN+ + ++ RA+ + R+ T S +++ EE++ K LK
Sbjct: 1456 LLAEE-----KNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLK 1510
Query: 172 TVFERLRLEQQRIENDLSDW--SIKILDHSLEEKTNPLSELPIELES-------LECPYP 222
E L + + ++ + S + L+ +EE L EL EL++ LE
Sbjct: 1511 AEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQ 1570
Query: 223 DLKSSILSEFYKFTQKYQKKLQDFNLQLEDIYRNCQLSEEDHWIYQAILDQYPGDLFGRR 282
LK + ++ ++K + QL + + + + A + GDL
Sbjct: 1571 ALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLE 1630
Query: 283 TLYLDMLQRYFPHKSRHDLVEH-----------EKYCDQYRFAIEQQNILISNWNKNRKD 331
LQ K R + ++ ++ + R A + + N+ +
Sbjct: 1631 ------LQADSAIKGREEAIKQLRKLQAQMKDFQRELEDAR-ASRDEIFATAKENEKKAK 1683
Query: 332 FIQKAVLTLTEACATHEMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEISAR 391
++ ++ L E A E A +K +EL +L + + A Q+E RLE I+
Sbjct: 1684 SLEADLMQLQEDLAAAERARKQADLEK--EELAEELASSLSGRNALQDEKRRLEARIAQL 1741
Query: 392 RREKEEEKEKLWKKKELLQRA-EKKKKIKKYWAKKKQKWQEME--MRDLQRL-EELKKLI 447
E EEE+ + + +++A ++ +++ A ++ Q+ E + L+R +EL+ +
Sbjct: 1742 EEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKL 1801
Query: 448 AEQSLKDRERVKYRQELLERRLMEKKEVALQEAHEDKERARRLEALRKQV-AVVAQFDPV 506
E + + K LE ++ + +E QEA E + + L+ K++ ++ Q +
Sbjct: 1802 HEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDE 1861
Query: 507 RMMSDTMASKARMG 520
R M++ +A G
Sbjct: 1862 RKMAEQYKEQAEKG 1875
Score = 56.6 bits (135), Expect = 6e-08
Identities = 111/576 (19%), Positives = 234/576 (40%), Gaps = 85/576 (14%)
Query: 30 QQLRALTEA-KKLASASAKLKIRKAMLTSKLSKEQTLIKQHKQVWWQEYQRLNEVRCKME 88
Q + LTE ++ A A L K L KE + +V Q Q + + K+E
Sbjct: 1203 QAVEELTEQLEQFKRAKANLDKNK----QTLEKENADLAGELRVLGQAKQEVEHKKKKLE 1258
Query: 89 SEIKSLLNEENIGNECLCDLTNFEQELSEQQCTYLKNVINPIQQLRADLKYRQHHTLQHS 148
++++ L ++ + G +L + +L N ++ + L + ++ +
Sbjct: 1259 AQVQELQSKCSDGERARAELNDKVHKLQ-----------NEVESVTGMLNEAEGKAIKLA 1307
Query: 149 HPHIEFNSM-----KVLEEVDFVKKQLKTVFERLRLEQQRIENDLSDWSIKILDHSLEEK 203
+S ++L+E K + T +L E+ +++ L D +E K
Sbjct: 1308 KDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQL--------DEEMEAK 1359
Query: 204 TN---PLSELPIELESLECPYPDLKSSILSEFYKFTQKYQKKLQDFNLQLEDIYRNCQLS 260
N +S L I+L + D S++ + +++QK++++ Q E+
Sbjct: 1360 QNLERHISTLNIQLSDSKKKLQDFASTV-EALEEGKKRFQKEIENLTQQYEEKAAAYDKL 1418
Query: 261 EEDHWIYQAILDQYPGDLFGRRTLY--LDMLQRYFPHKSRHDLVEHEKYCDQYRFA---- 314
E+ Q LD DL +R L L+ QR F + KY D+ A
Sbjct: 1419 EKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEA 1478
Query: 315 -----------------------IEQQNILISNWNKN---RKDFIQKAV--LTLTEACAT 346
+E+ N ++ ++ KD + K V L ++
Sbjct: 1479 REKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALE 1538
Query: 347 HEMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKLWKKK 406
+ME M + ++ + EL A AK+R Q + E ++ AR + EE++ +L ++
Sbjct: 1539 TQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQL 1598
Query: 407 ELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQELLE 466
+ + ++ ++ A +K E +++DL+ + E+++K +++ + + +
Sbjct: 1599 HEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQ 1658
Query: 467 RRLME---KKEVALQEAHEDKERARRLEALRKQVAVVAQFDPVRMMSD-TMASKARMGIE 522
R L + ++ A E++++A+ LEA D +++ D A +AR +
Sbjct: 1659 RELEDARASRDEIFATAKENEKKAKSLEA-----------DLMQLQEDLAAAERARKQAD 1707
Query: 523 IEEEFILQKPLFTLNTYNEQQIISDPRLRFELALRE 558
+E+E + ++ +L+ N Q D + R E + +
Sbjct: 1708 LEKEELAEELASSLSGRNALQ---DEKRRLEARIAQ 1740
Score = 56.6 bits (135), Expect = 6e-08
Identities = 102/511 (19%), Positives = 217/511 (42%), Gaps = 73/511 (14%)
Query: 9 DNLVFHMKNEMR---NIKYKPVDYQQLRA--------LTEAKKLASASAKLKIRKAMLTS 57
D+LV + N+ + N++ K + QL A + + A A A+ K KA+ +
Sbjct: 1430 DDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLA 1489
Query: 58 KLSKEQTLIKQHKQVWWQEYQRLNEVRCKMESEIKSLLNEENIGNECLCDLTNFEQELSE 117
+ +E K+ E +R N++ +++E++ L++ ++ + + +L ++ L E
Sbjct: 1490 RALEEALEAKE-------ELERTNKM---LKAEMEDLVSSKDDVGKNVHELEKSKRAL-E 1538
Query: 118 QQCTYLKNVINPIQ---QLRADLKYRQHHTLQHSHPHIEFNSMKVLEEVDFVKKQLKTVF 174
Q +K + ++ Q D K R +Q E + E+ + ++QL+
Sbjct: 1539 TQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQL 1598
Query: 175 ERLRLE--------------QQRIENDLSDWSIKILDHSL---EEKTNPLSELPIELESL 217
E ++++E DL D ++ D ++ EE L +L +++
Sbjct: 1599 HEYETELEDERKQRALAAAAKKKLEGDLKDLELQA-DSAIKGREEAIKQLRKLQAQMKDF 1657
Query: 218 ECPYPDLKSSILSEFYKFTQKYQKKLQDFNLQL----EDIYRNCQLSEEDHWIYQAILDQ 273
+ D ++S E + ++ +KK + L ED+ + ++ + + ++
Sbjct: 1658 QRELEDARAS-RDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEE 1716
Query: 274 YPGDLFGRRTLY-----LDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNILISNWNKN 328
L GR L L+ + + E D+ R A +Q L SN
Sbjct: 1717 LASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQL-SNELAT 1775
Query: 329 RKDFIQKAVLTLTEACATHEMESMLAKDKKKQQELCADLKAKVRQWRAHQE-EVARLEME 387
+ QK A ++E + + K E+ +K+K + A E ++A+LE +
Sbjct: 1776 ERSTAQK------NESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQ 1829
Query: 388 ISARRREKEEE----KEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEEL 443
+ REK+ K+K K KE+L + E ++K+ + + ++ +K R+++L
Sbjct: 1830 VEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN-------ARVKQL 1882
Query: 444 KKLIAEQSLKDRERVKYRQELLERRLMEKKE 474
K+ + E++ ++ +R+ + L+R L E E
Sbjct: 1883 KRQL-EEAEEESQRINANRRKLQRELDEATE 1912
Score = 45.8 bits (107), Expect = 1e-04
Identities = 116/560 (20%), Positives = 239/560 (42%), Gaps = 83/560 (14%)
Query: 57 SKLSKEQTLIKQHKQVWWQEYQRLNEVRCKMESEIKSLLNEENIGNECLCDLTNFE---Q 113
S+L++E+ L+++ Q + Y E+R ++ ++ + L E I +E L E Q
Sbjct: 883 SQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQEL---EEILHEMEARLEEEEDRGQ 939
Query: 114 ELSEQQCTYLKNVINPIQQLRADLKYRQHHTLQHSHPHIEFNSMKVLEEVDFVKKQLKTV 173
+L ++ + +++ +QL + RQ LQ E K+ +E+ + Q
Sbjct: 940 QLQAERKKMAQQMLDLEEQLEEEEAARQK--LQLEKVTAEAKIKKLEDEILVMDDQNN-- 995
Query: 174 FERLRLEQQRIENDLSDWSIKILDHSLEEKTNPLSELPIELESLECPYP-DLKSSILS-- 230
+L E++ +E +SD + + + EEK L++L + ES+ LK S
Sbjct: 996 --KLSKERKLLEERISDLTTNLAEE--EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQ 1051
Query: 231 EFYKFTQKYQKKLQDFNLQLEDIYRNC-----QLSEEDHWIYQAI--LDQYPGDLFGRRT 283
E K +K + DF+ Q+ D+ QL++++ + A+ LD D ++
Sbjct: 1052 ELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLD----DEIAQKN 1107
Query: 284 LYLDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNILISNWNKNRKDFIQKAVLTLTEA 343
L ++ H S DL E ++ + + K ++D ++ TE
Sbjct: 1108 NALKKIRELEGHIS--DLQED----------LDSERAARNKAEKQKRDLGEELEALKTEL 1155
Query: 344 CATHEMESMLAKDK-KKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKL 402
T + + + + K++QE+ KA + R+H+ +V + R+K +
Sbjct: 1156 EDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEM--------RQKHAQ---- 1203
Query: 403 WKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQ 462
+EL ++ E+ K+ K K K Q +E + EL+ L + ++ V++++
Sbjct: 1204 -AVEELTEQLEQFKRAKANLDKNK---QTLEKENADLAGELRVL-----GQAKQEVEHKK 1254
Query: 463 ELLERRLMEKKEVALQEAHEDKERAR-----RLEALRKQVAVV------AQFDPVRMMSD 511
+ LE ++ E LQ D ERAR ++ L+ +V V A+ +++ D
Sbjct: 1255 KKLEAQVQE-----LQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKD 1309
Query: 512 TMASKARMGIEIEEEFILQKPLFTLNTYNEQQIISDPRLRFELAL---REAGLHRTLYAK 568
+ ++ ++ +E + ++ LN + + + + R + L EA + +
Sbjct: 1310 VASLSSQ--LQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHIS 1367
Query: 569 EILPKISPQKPPRKDMESTV 588
+ ++S K +D STV
Sbjct: 1368 TLNIQLSDSKKKLQDFASTV 1387
Score = 43.1 bits (100), Expect = 7e-04
Identities = 47/183 (25%), Positives = 88/183 (48%), Gaps = 21/183 (11%)
Query: 350 ESMLAKDKKKQQELCADLKAKVRQW-RAHQE-----EVARLEMEISARRREKEEEKEKLW 403
+ L K Q+ A LK + QW R + +V R E E+ A+ E ++ KE+
Sbjct: 810 QQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQ 869
Query: 404 KK----KELLQR----AEKKKKIKKYWAKKKQKW---QEMEMRDLQRLEELKKLIAEQSL 452
K KEL Q+ E+K +++ + + + +EM +R + +EL++++ E
Sbjct: 870 KAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEA 929
Query: 453 KDRERVKYRQEL-LERRLMEKKEVALQEAHEDKERAR---RLEALRKQVAVVAQFDPVRM 508
+ E Q+L ER+ M ++ + L+E E++E AR +LE + + + D + +
Sbjct: 930 RLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILV 989
Query: 509 MSD 511
M D
Sbjct: 990 MDD 992
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 60.5 bits (145), Expect = 4e-09
Identities = 111/552 (20%), Positives = 232/552 (42%), Gaps = 73/552 (13%)
Query: 10 NLVFHMKNEMRNIKYKPVDYQQLRALTEAKKLASASAKLKIRKAMLTSKLSKEQTLIKQH 69
N + ++ + N + + Q R + L + + +A L ++ TL
Sbjct: 1233 NELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISF 1292
Query: 70 KQVWWQEYQRLNEVRCKMESEIKSLL-----------NEENIGNECLCDLTNFEQELSE- 117
+Q Q ++ N+++ M+++I+SL+ N++ +E +T ++ELSE
Sbjct: 1293 QQATHQLEEKENQIK-SMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSEN 1351
Query: 118 --------QQCTYLKNVINPIQQLRADLKYRQHHTLQHSHPHIEFNSMK---------VL 160
++ K I+ + + DL + +++ S +S++ +L
Sbjct: 1352 INAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELL 1411
Query: 161 EEVDFVKKQLKTVFERLRLEQQRIE---NDLSDWSIKILDHSLEEKTNPLSELPIELE-- 215
++V + ++ T+ + ++++ N S+W K + + N + EL I+LE
Sbjct: 1412 DQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQ-NTVKELQIQLELK 1470
Query: 216 SLECPYPDLKSSILSEFYKFTQKYQKKLQDFNLQLEDIYRNCQLSE---EDHWIYQAILD 272
S E D + ++L E + K+ ++ED + E E Q
Sbjct: 1471 SKEAYEKDEQINLLKEEL---DQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARI 1527
Query: 273 QYPGDLFGRRTLYLDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNILISNWNKNRKDF 332
D ++T+ ++ L + ++ +EH++ + + E + NR
Sbjct: 1528 MELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQE-----LGEEKDNRVKE 1582
Query: 333 IQKAVLTLTEACATHEMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEISARR 392
++ +LTL + M++ L KK+ + + +K+K + +A ++ RLE E +A+
Sbjct: 1583 AEEKILTLENQ--VYSMKAELETKKKELEHVNLSVKSKEEELKALED---RLESESAAKL 1637
Query: 393 RE---KEEEKEKLWKKKELLQRAEKKKKIKK----YWAKKKQKWQEMEMRDLQRLEELKK 445
E K E+K KK+ L Q EK+++ KK + ++ K QE E R++ LEE K
Sbjct: 1638 AELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQERE-REVHILEEKLK 1696
Query: 446 ---------LIAEQSLKD----RERVKYRQELLERRLMEKKEVALQEAHEDKERARRLEA 492
LI +S K+ E+ + + ++ E+K LQ +KE+ +
Sbjct: 1697 SVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVG 1756
Query: 493 LRKQVAVVAQFD 504
K+ V + F+
Sbjct: 1757 QEKEETVSSHFE 1768
Score = 53.9 bits (128), Expect = 4e-07
Identities = 110/527 (20%), Positives = 216/527 (40%), Gaps = 66/527 (12%)
Query: 18 EMRNIKYKPVDYQQLRALTEAKKLASA-SAKLKIRKAMLTSKLSKEQTLIKQHKQVWWQE 76
EM + +D +Q TE + L+S S LK R KL +E +++K QE
Sbjct: 670 EMNEKTLEKLDVKQ----TELESLSSELSEVLKARH-----KLEEELSVLKDQTDKMKQE 720
Query: 77 YQ-RLNEVRCKMESEIKSLLNEENIG----NECLCDLTNFEQELSEQQCTYLKNVINPIQ 131
+ +++E + + ++ S++ E + + L D N + L +++ +LK ++
Sbjct: 721 LEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVE 780
Query: 132 QLRADLKYRQHHTLQHSHPHIEFNSMKVL--EEVDFVKKQLKTVFERLR-LEQQRIENDL 188
L AD+K + Q S F S + E+ ++QL + ++L LE +RI L
Sbjct: 781 NLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERI---L 837
Query: 189 SDWSIKILDHSLEEKTNPLSELPIELESLECPYPDLKSSILSEFYKFTQKYQKKLQDFNL 248
+ ++ ++ L I+++ L S + + TQ Y+ KL+D N
Sbjct: 838 LTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNK 897
Query: 249 QLEDIYRNCQLSEEDHWIYQA-----------------------ILDQYPGDLFGRRTLY 285
+ E + L E+++ I Q IL++ F +
Sbjct: 898 EQEQTKQI--LVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKK 955
Query: 286 LDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNILISNWNKNRKDFIQKAVLTLTEACA 345
++ +++ K + ++ + + + E +N + K ++ + + +
Sbjct: 956 MEKVKQ--KAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAG 1013
Query: 346 THEMESMLAKDKKKQQELCADLKAK-----VRQWRAHQEEVARLEMEI-SARRREKEEEK 399
+ S L ++K+Q E ++ + + W + A EI + +EKE+E
Sbjct: 1014 ISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEV 1073
Query: 400 EKLWKKKELLQRAEKKKKIKKY-WAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERV 458
+L K+K LL EK++ K+ W K++ Q+ + +LQ + K +D ++
Sbjct: 1074 AEL-KQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKL 1132
Query: 459 KYRQELLERRLME--KKEVALQE--------AHEDKERARRLEALRK 495
K E LE L + K+ LQE A EDK + L + K
Sbjct: 1133 KAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLK 1179
Score = 52.4 bits (124), Expect = 1e-06
Identities = 94/453 (20%), Positives = 196/453 (43%), Gaps = 44/453 (9%)
Query: 52 KAMLTSKLSKEQTLIKQHKQVWWQEYQ-RLNEVRCKMESEIKSLLNEENI--------GN 102
K L S ++ L + QV Q+YQ + ++R K E E ++LL ++ I N
Sbjct: 613 KTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMN 672
Query: 103 ECLCDLTNFEQELSEQQCTYLKNVINPIQQLRADLKYRQHHTLQHSHPHIEFNSMKVLEE 162
E + + +Q E + L V+ +L +L + T +E K+ E+
Sbjct: 673 EKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQT-DKMKQELE---AKMDEQ 728
Query: 163 VDFVKKQLKTVFERLRLEQQRIENDLSDWSIKILDHSLEEKTNPLSELPIELESLECPYP 222
+ ++Q+ ++ + + QR E L D I L+ L+E+ L E +E+LE
Sbjct: 729 KNHHQQQVDSIIKEHEVSIQRTEKALKD-QINQLELLLKERDKHLKEHQAHVENLEA--- 784
Query: 223 DLKSSILSEFYKFTQKYQKKLQDFNLQLEDIYRNCQ-LSEEDHWIYQAILDQYPGDLFGR 281
D+K S + +LQ + +L D++++ Q + E Y+ L Q L
Sbjct: 785 DIKRS------------EGELQQASAKL-DVFQSYQSATHEQTKAYEEQLAQLQQKLLDL 831
Query: 282 RTLYLDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNILISNWNKNRKDFIQKAVLTLT 341
T + + ++ +++ V E D ++ ++ L+ K + QK V +LT
Sbjct: 832 ETERILLTKQVAEVEAQKKDVCTE--LDAHKIQVQD---LMQQLEKQNSEMEQK-VKSLT 885
Query: 342 EACATHEMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEK 401
+ ES L +D K+QE + + E + E+EI ++ +E+
Sbjct: 886 QV-----YESKL-EDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIH 939
Query: 402 LWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVK-Y 460
+ ++ + ++KK++K K K+ + ++ + L + +LKK + +L+ ++ K +
Sbjct: 940 ILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQF 999
Query: 461 RQELLERRLMEKKEVALQEAHEDKERARRLEAL 493
++LE ++ + + + ++E+L
Sbjct: 1000 NAKMLEMAQANSAGISDAVSRLETNQKEQIESL 1032
Score = 48.5 bits (114), Expect = 2e-05
Identities = 110/562 (19%), Positives = 221/562 (39%), Gaps = 90/562 (16%)
Query: 18 EMRNIKYKPVDYQQLRALTEAKKLASASAKLKIRKAMLT----SKLSKEQTLIKQHKQVW 73
E+ K V + + LT ++ S A+L+ +K L S SKE+ L ++
Sbjct: 1571 ELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLE 1630
Query: 74 WQEYQRLNEVRCKMESEIKSLLNEENIGNECLCDLTNFEQELSEQQCTYLKNVINPIQQL 133
+ +L E++ K E +I ++ + ++ E++ Y K + + +L
Sbjct: 1631 SESAAKLAELKRKAEQKIAAIKKQ-------------LLSQMEEKEEQYKKGTESHLSEL 1677
Query: 134 RADLKYRQH--HTLQHSHPHIEFNSMKVLEEVDFVKKQLKTVFERLRLEQQRIENDLSDW 191
L+ R+ H L+ +E + + L V K + E+ + Q +
Sbjct: 1678 NTKLQEREREVHILEEKLKSVESSQSETLI-VPRSAKNVAAYTEQEEADSQGCVQKTYEE 1736
Query: 192 SIKILDHSLEEKTNPLSELPIELESLECPYPDLKSSILSEFYKFTQKYQKKLQDFNLQLE 251
I +L +L EK L + E E + +++ K K+ +D ++
Sbjct: 1737 KISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSM--- 1793
Query: 252 DIYRNCQLSEEDHWIYQAILDQYPGDLFGRRTLY--------LDMLQRYFPHKS------ 297
I + EE + Y I+ Q+ G+ + D +Q+ K
Sbjct: 1794 -IGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQIL 1852
Query: 298 ---------------RHDLVEHEKYCDQYRF--AIEQQN-------ILISNWNKNRKDFI 333
VE E+ +Y A++Q + +L N + K +
Sbjct: 1853 EQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHL 1912
Query: 334 QKAVLTLTEACATHEMESMLAKDKKKQQELCAD---LKAKVRQWRA-HQEEVARLEMEIS 389
+ L +++E LA ++++Q+L + L+ +R R HQ+E+ L+ E
Sbjct: 1913 VQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYD 1972
Query: 390 ARRREK-EEEKEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIA 448
R EK ++E+E L EL + K+ ++++ + QK QE+EM + + + +++ A
Sbjct: 1973 QEREEKIKQEQEDL----ELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEA 2028
Query: 449 EQSLKDRERVKYRQELLERRLMEKKEVALQEAHED---KERARRLEAL--RKQVAVVAQF 503
ELLE E ++ + A +D K A+R E + ++ + A+
Sbjct: 2029 --------------ELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKV 2074
Query: 504 DPVRMMSDTMASKARMGIEIEE 525
++ + + K + +E EE
Sbjct: 2075 RDLQTQLEELQKKYQQKLEQEE 2096
Score = 42.4 bits (98), Expect = 0.001
Identities = 97/529 (18%), Positives = 220/529 (41%), Gaps = 62/529 (11%)
Query: 55 LTSKLSKEQTLIKQHKQVWWQEYQRLNEVRCKMESEIKSLLNEENIGNECLCDLTNFEQE 114
L ++ +++ L+K+ K+ ++ + + E+ ++ L+E E + DL E+
Sbjct: 284 LQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEA-LQEQLDERLQELEKIKDLHMAEKT 342
Query: 115 LSEQQCTYLKNVINPIQQLR----ADLKYRQHHTLQHSHPHIEFNSMKVLEEVDFVKKQL 170
Q KN+I ++Q + A+ K + H TL+ I ++ KQ+
Sbjct: 343 KLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRI--------KQM 394
Query: 171 KTVFERLRLEQQRIENDLSDWSIKILD--HSLEEKTNPL-SELPIELESLECPYPDLKSS 227
T E LR ++++ E + K L EE L +E+ +++++E + + S
Sbjct: 395 TTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERIS 454
Query: 228 ILSEFYKFTQKY----QKKLQDFNLQLEDIYRNCQLSEEDHWIYQAILDQYPGDLFGRRT 283
+ E + Q+ +K ++ +L+ ++ +L+ ++ + + + + R
Sbjct: 455 LQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEK-ELARKEQELTKKLQTR-------ERE 506
Query: 284 LYLDMLQRYFPHKSRHDLVEHEKYCDQYRFAIE----QQNILISNWNKNRKDFIQKAVLT 339
M +S + + EK Q A+E Q+ +++ +D Q+A
Sbjct: 507 FQEQMKVALEKSQSEYLKISQEKE-QQESLALEELELQKKAILTESENKLRDLQQEAETY 565
Query: 340 LTEACATHEMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEK 399
T E+ES L K ++ + DL + + E + EI+ + + E
Sbjct: 566 RTRIL---ELESSLEKSLQENKNQSKDLAVHL------EAEKNKHNKEITVMVEKHKTEL 616
Query: 400 EKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERV- 458
E L +++ L W +K Q ++ ++++L E + E LKD+E +
Sbjct: 617 ESLKHQQDAL------------WTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIF 664
Query: 459 KYRQELLERRLMEKKEVALQE----AHEDKERARRLEALRKQVAVVA-QFDPVRMMSDTM 513
+ E + + +EK +V E + E E + L ++++V+ Q D ++ +
Sbjct: 665 QAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAK 724
Query: 514 ASKARMGIEIEEEFILQKPLFTLNTYNEQQIISDPRLRFELALREAGLH 562
+ + + + + I+++ ++ ++ + D + EL L+E H
Sbjct: 725 MDEQKNHHQQQVDSIIKE--HEVSIQRTEKALKDQINQLELLLKERDKH 771
Score = 37.4 bits (85), Expect = 0.039
Identities = 96/487 (19%), Positives = 207/487 (42%), Gaps = 98/487 (20%)
Query: 26 PVDYQQLRALTEAKKLASASAKLKIRK---AMLTSKLSKEQTLIKQHKQVWWQEYQRLNE 82
P + + A TE ++ S K + ++L L++++ L+++ Q + E
Sbjct: 1709 PRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFE 1768
Query: 83 VRCKMESEIKSLLNEENIGNECLCDLTNFEQELSEQQCTYLKNVINPIQQL--RADLKYR 140
+RC+ + + L + E +E + + ++EL E+ Y V +++ + +++ +
Sbjct: 1769 MRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAK 1828
Query: 141 QH---------HTLQHSHPHIEFNSMKVLE---------EVDFVK-KQLKTVFERLRLEQ 181
Q+ TLQ + K+ E EV V+ ++L + +E+L+ Q
Sbjct: 1829 QNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQ 1888
Query: 182 QRIENDLSDWSIKILDHSLEEKTNPLSELPIELESLECPYPDLKSSILSEFYKFTQKYQK 241
Q D + ++L+ + EEK+ P L ++E + DL+ + ++
Sbjct: 1889 QM---DGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGA--------ER 1937
Query: 242 KLQDFNLQLEDIYRNCQLSEEDHWIYQAILDQYPGDLFGRRTLYLDMLQRYFPHKSRHDL 301
+ Q ++ + ++ ++ ++H IL K +D
Sbjct: 1938 EKQKLGKEIVRLQKDLRMLRKEHQQELEIL------------------------KKEYDQ 1973
Query: 302 VEHEKYCDQYRFAIEQQNILISNWNKNRKDFIQKAVLTLTEACATHEMESMLAKDKKKQQ 361
EK EQ+++ + + N K +++ L + E+E + + K Q
Sbjct: 1974 EREEK------IKQEQEDLELKH-NSTLKQLMREFNTQLAQ--KEQELEMTIKETINKAQ 2024
Query: 362 ELCADLKAKVRQWRAHQEEVARL---------EMEISARRREK---EEEKEKLWKKKELL 409
E+ A+L +HQEE +L +++ +A+R E+ E+E K ++L
Sbjct: 2025 EVEAEL------LESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQ 2078
Query: 410 QRAEKKKKIKKYWAKKKQKW----QEMEMRDLQ-RLEELKKLIAEQSLKDRERVKYRQEL 464
+ E+ + KKY K +Q+ + + +LQ +L + LI++ LK++E +R+++
Sbjct: 2079 TQLEELQ--KKYQQKLEQEENPGNDNVTIMELQTQLAQKTTLISDSKLKEQE---FREQI 2133
Query: 465 --LERRL 469
LE RL
Sbjct: 2134 HNLEDRL 2140
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 60.1 bits (144), Expect = 6e-09
Identities = 121/530 (22%), Positives = 228/530 (43%), Gaps = 103/530 (19%)
Query: 12 VFHMKNEMRNIKYKPVDYQQLRALTEAKKLASASAKLKIRKAMLTSK--LSKEQTLIKQH 69
V K ++ + K V + A + +KLA KL + KAM+ K L E + K+
Sbjct: 1902 VIKKKEKLAETEKKLVQVEDSLAKKQ-EKLAQEKMKLALEKAMVQGKKRLRGELDIAKEE 1960
Query: 70 KQVWWQEYQRLNEVRCKMESEIKSLLNEENIGNECLCDLTNFEQELSEQQCTYLKNVINP 129
K + E +RL E + ++ ++L E +T EQEL E++ + + ++
Sbjct: 1961 KALNL-EMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKIL-- 2017
Query: 130 IQQLRADLKYRQHHTLQHSHPHIEFNSMKVLEEVDFVKKQLK-TVFERLRLEQQRIENDL 188
+ + + +EE + K +L+ T +R+ ++ QR L
Sbjct: 2018 ----------------------LHEDRILAMEESEIAKGKLEFTRGQRIFVQGQR---KL 2052
Query: 189 SDWSIKILDHSLEEKTNPLSELPIELESLECPYPDLKSSILSEFYKFTQKYQKKLQDFNL 248
+ S K++ +K LS+ P +L + IL K T+ ++KL +
Sbjct: 2053 AKASRKLI-----KKRESLSKEPAKL-----------NKILKALQKLTRD-ERKLTQEEI 2095
Query: 249 QLEDIYRNCQLSEEDHWIYQAILDQYPGDLFGRRTLY------LDMLQRYFPHKSRHDLV 302
++ + R + E I Q+ LD D +R+ L QR +K R +
Sbjct: 2096 KMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMIN 2155
Query: 303 EHEKYC----------------DQYRFAIEQQNI---LISNWNKNRK---------DFIQ 334
+ EK D+ IE++ + L W K ++ F
Sbjct: 2156 KEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSS 2215
Query: 335 KAVLTLTEACATHEMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEISARRRE 394
+ +E + EMES+L + +KQ+ L ++ + + + +EE R E E R+E
Sbjct: 2216 QVDEVESEEHFSEEMESLL-DELEKQESLSSEEEEEREEEEEREEEEVREEEE---ERKE 2271
Query: 395 KEEEKEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAE---QS 451
+EE +EK +K+E +KKKK + KKK++ QE E + EE +++++E +S
Sbjct: 2272 EEEGEEKQVEKEE---EEKKKKKKE----KKKEEVQEKE----EVFEEKEEIMSEEETES 2320
Query: 452 LKDRERVKYRQELLERRLMEKKEVALQEAHEDKERARRLEALRKQVAVVA 501
L D E + L E +++++ L++ + K + +R ++LR + V++
Sbjct: 2321 LSDEEEEEESCSLEEE--VDREKEILKKEKQFKLQEQRRKSLRGRERVLS 2368
Score = 48.1 bits (113), Expect = 2e-05
Identities = 92/516 (17%), Positives = 206/516 (39%), Gaps = 43/516 (8%)
Query: 33 RALTEAKKLASASAKLKIRKAMLTSKLSKEQTLIKQHKQVWWQEYQRLNEVRCKMESEIK 92
R L E +KL A KLS E+ ++++ K++ W+E++++ E +S+ +
Sbjct: 1488 RLLQEEEKLHQAG-----------EKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQ 1536
Query: 93 SLLNEENIGNECLCDLTNFEQELSEQQCTYLKNVINP------IQQLRADLKYRQHHTLQ 146
+EE + E + + E E EQQ T + I I + RA + ++ Q
Sbjct: 1537 QYKDEEEVTLE---EEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKR---AQ 1590
Query: 147 HSHPHIEFNSMKVLEEVDFVKKQLKTVFERLRLEQQRIENDLSDWSIKILDHSLEEKTNP 206
+ EE +++ K +++ Q E ++ + +L ++
Sbjct: 1591 EERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEK 1650
Query: 207 LSELPIELESLECPYPDLKSSILSEFYKFTQKYQKKLQDFNLQLEDIYRNCQLSEEDHWI 266
LS+ +L + E K +K K + N+ + + Q + W
Sbjct: 1651 LSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQ 1710
Query: 267 YQAILDQYPGDLFGRRTLYLDMLQRYFPHKSRHD----LVEHEKYCDQYRFAIEQQNILI 322
+ + + L DM + + + + LVE +K + A+ Q +
Sbjct: 1711 EKELAQEL-------EELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKL 1763
Query: 323 SNWNKNRKDFIQKAVLTLTEACATH-----EMESMLAKDKKKQQELCADLKAKVRQWRAH 377
S + + ++ ++ E A H E E L + +++ E L K +W
Sbjct: 1764 SE-EETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINS 1822
Query: 378 QEEVARLEMEISARRREKEEEKEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDL 437
EE+ + +M + ++ +E+K +K++L QR E K+ K++ +++ + L
Sbjct: 1823 MEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNK-L 1881
Query: 438 QRLEELKKLIAEQSLKDRERVKYRQELLERRLMEKKEVALQEAHEDKERARRLEALRKQV 497
++ + E+ +++E V ++E L EKK V ++++ K+ E ++ +
Sbjct: 1882 GMFNKILAQVEEKLTQEKETVIKKKEKLAE--TEKKLVQVEDSLAKKQEKLAQEKMKLAL 1939
Query: 498 AVVAQFDPVRMMSDTMASKARMGIEIEEEFILQKPL 533
R+ + +K + +E + + ++ +
Sbjct: 1940 EKAMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKM 1975
Score = 33.1 bits (74), Expect = 0.74
Identities = 25/154 (16%), Positives = 77/154 (50%), Gaps = 13/154 (8%)
Query: 348 EMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEME-ISARRREKEEEKEKLWKKK 406
+ E + K K++ + D+ +V + +E+V + E + + R ++ +K W +
Sbjct: 1408 QKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQEGKLVMIERTPSWQDWKKAWDEW 1467
Query: 407 ELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIA--EQSLKDRERVKYRQ-- 462
+ + +K W K++W++ +++ ++L + + ++ E+ L++ +++K+ +
Sbjct: 1468 KQVHGETRKS-----WKAWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWK 1522
Query: 463 ELLERRLMEKKEVALQEAHEDKERARRLEALRKQ 496
++ E L K + ++ ++D+E E + ++
Sbjct: 1523 QVWENMLSSKSK---EQQYKDEEEVTLEEEVSRE 1553
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 60.1 bits (144), Expect = 6e-09
Identities = 117/572 (20%), Positives = 238/572 (41%), Gaps = 97/572 (16%)
Query: 9 DNLVFHMKNEMRNIKYKPVDYQQLRALTEAKKLASASAKLKIRKAMLTSK---------- 58
D L K E+ + ++ + +L A + A+ ++ + M+T K
Sbjct: 317 DALKKSSKGELTTLIHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMTEKERSNVVITRM 376
Query: 59 ------LSKEQTLIKQHKQVWWQEYQRLN----EVRCKMESEIKSLLNEENIGNECLCDL 108
L KE + + V +QE Q++ +VR +ME+EI L E I + + +
Sbjct: 377 KDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNT 436
Query: 109 TN-FEQELSEQQCTYLKNVINPIQQLRADLKYRQHHTLQHSHPHIEFNSMKV-LEEVDFV 166
TN E + S + ++ + +L Q +Q + +KV L+E +
Sbjct: 437 TNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAERR 496
Query: 167 KKQLKTVFERLRLEQQRIENDLSDWSIKILDHSLEEKTNPLSELPIELESLECPYPDLKS 226
+++++ + E + + DL ++ ++ + L++ + + LE
Sbjct: 497 WEEVQSYIRKRTAEHEAAQQDLQS-KFVAKENEVQSLHSKLTDTLVSKQQLE-------- 547
Query: 227 SILSEFYKFTQKYQKKLQDFNLQLEDIYRNCQLSEEDHWIYQAILDQYPGDLFGR--RTL 284
L + + QK K + +Q++DI E + +A + Q+ + + ++
Sbjct: 548 QRLMQLMESEQKRVNKEESLQMQVQDIL-------EQNEALKAQIQQFHSQIAAQTSASV 600
Query: 285 YLDMLQRYFPHKSRH-DLVEHEKYCDQYRFAIEQQNIL-ISNWNKNRKDFIQK-AVLTLT 341
+ L + K + E ++ R +++ + I N N K +QK L
Sbjct: 601 LAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANE 660
Query: 342 EACATHEME----SMLAKDKK---KQQELCADLKAKVRQW-------RAHQEEVARLEME 387
+A A HE+E S+ KD K +++L ++ K+ ++ +A + EV +L+
Sbjct: 661 QAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTL 720
Query: 388 IS-------ARRREK--EEEKEKLWKKKELLQ----------------RAEKKKKIKKYW 422
+S + EK +E+ EKL +ELL+ R E K+
Sbjct: 721 VSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQ 780
Query: 423 AKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQELLERRLME--KKEVALQEA 480
K ++ ++ L +EELKK+I E+ K +K +ELLE L++ KE +Q+
Sbjct: 781 DLKAKQNDQVSFASL--VEELKKVIHEKDGK----IKSVEELLEAELLKVANKEKTVQDL 834
Query: 481 HEDKERARRLEALRKQVAVVAQFDPVRMMSDT 512
++ ++AL++++ V Q + + +S T
Sbjct: 835 KQE------IKALKEEIGNV-QLEKAQQLSIT 859
Score = 44.7 bits (104), Expect = 2e-04
Identities = 100/517 (19%), Positives = 209/517 (40%), Gaps = 45/517 (8%)
Query: 12 VFHMKNE---MRNIKYKPVDYQQLRALTEAKKLASASAKLKIRKAMLTSKLSKEQTLIKQ 68
+ H+K E +R+ + + + E KL A+L T KL +E+ K
Sbjct: 419 IAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKN 478
Query: 69 HKQVWWQEYQRLNEVRCKMESEIKSLLNEENIGNECLCDLTNFEQELSEQQCTYLKNVIN 128
+Q Q +L E + E E++S + + +E + E + L + +
Sbjct: 479 AEQAATQLKVQLQEAERRWE-EVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLT 537
Query: 129 PIQQLRADLKYRQHHTLQHSHPHIEFNSMKVLEEVDFVKKQLKTVFERLRLEQQRIENDL 188
+ L+ R ++ + ++ D +++ E L+ + Q+ + +
Sbjct: 538 DTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQN-----EALKAQIQQFHSQI 592
Query: 189 S-DWSIKILDHSLEEKTNPLSELPIELESLECPYPDLKSSILSEFYKFTQKYQ--KKLQD 245
+ S +L EE ++E +++ E S+ SE + T K + K +Q+
Sbjct: 593 AAQTSASVL---AEELHKVIAEKDKQIKQTE-------DSLASERDRLTSKEEELKDIQN 642
Query: 246 FNLQLEDIYRNCQLSEEDHWIYQAILDQYPGDLFGRRTLYLDMLQRYFPHKSRHDLVEHE 305
N L+ + Q + L++ ++ + + +L+ H+ + + E +
Sbjct: 643 MNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDK-IRLLEEQLQHEISNKMEEFK 701
Query: 306 KYCDQ---YRFAIEQQNILISNW-NKNRKDFIQKAVLTLTEACATHE--MESMLAKDKKK 359
DQ + +++ L+S NK+ + ++K + E T E +E+ L + K
Sbjct: 702 ILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATK 761
Query: 360 QQELCA-------------DLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKLWKKK 406
++EL A DLKAK + V L+ I + + + +E L +
Sbjct: 762 EEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELL--EA 819
Query: 407 ELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQELLE 466
ELL+ A K+K ++ + K +E+ L++ ++L Q L++ + K Q
Sbjct: 820 ELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTM 879
Query: 467 RRLMEKKEVALQEAHE-DKERARRLEALRKQVAVVAQ 502
+ ++E+KE L + ++ E+L+ V VAQ
Sbjct: 880 KAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQ 916
Score = 38.9 bits (89), Expect = 0.013
Identities = 92/478 (19%), Positives = 202/478 (42%), Gaps = 56/478 (11%)
Query: 10 NLVFHMKNEMRNIKYKPVDYQQLRALTEAKKLASA----SAKLKIRKAMLTSKLSKEQTL 65
N+ F +K E++ K + + +Q A E +K+ + K+++ + L ++S +
Sbjct: 642 NMNFLLKAEVQ--KLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKM-- 697
Query: 66 IKQHKQVWWQEYQRLNEVRCKMESEIKSL--LNEENIGNECLCDLTNFEQELSEQQCTYL 123
+E++ LN+ ++SE++ L L E + + + QE E+ L
Sbjct: 698 ---------EEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEK----L 744
Query: 124 KNVINPIQQ--LRADLKYRQHHTLQHSHPHIEFNSMKVLEEVDFVKKQLKTV-FERLRLE 180
K V ++ ++ K + + ++ NS E D KQ V F L E
Sbjct: 745 KTVEELLETGLIQVATKEEELNAIRTE------NSSLTKEVQDLKAKQNDQVSFASLVEE 798
Query: 181 QQRIENDLSDWSIKILDHSLEEKTNPLSELPIELESLECPYPDLKSSILSEFYKFTQKYQ 240
+++ ++ D IK ++ LE + +++ + E DLK I + +
Sbjct: 799 LKKVIHE-KDGKIKSVEELLEAEL-------LKVANKEKTVQDLKQEIKALKEEIGNVQL 850
Query: 241 KKLQDFNL--QLEDIYRNCQLSEEDHWIYQAILDQYPGDLFGRRTLYLDMLQRYFPHKSR 298
+K Q ++ +++++ + EE +A+L++ DL D+ + K+
Sbjct: 851 EKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAH 910
Query: 299 -HDLVEHEKYCDQYRFAIEQQNILISNWNKNRKDFIQKAVLTLTEACATHEMESMLAKDK 357
++ +H E+ I++ K +++ +++ L E + ++ L +D
Sbjct: 911 VQEVAQHNLKEASSASQFEELEIVL----KEKENELKRLEAMLKERESDLSSKTQLLQDV 966
Query: 358 KKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKLWKKKELLQRAEKKKK 417
+ + +L +++Q Q E+ E+E+E LW + + L+ A + ++
Sbjct: 967 QDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQR 1026
Query: 418 IKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQELLERRLMEKKEV 475
KK +++ W+ ME L +K++ + K + K RQ+ +E +E KEV
Sbjct: 1027 -KKNNDLREKNWEAME-----ALASTEKMLQD---KVNKTSKERQQQVEAVELEAKEV 1075
Score = 36.6 bits (83), Expect = 0.067
Identities = 103/533 (19%), Positives = 209/533 (39%), Gaps = 80/533 (15%)
Query: 15 MKNEMRNIKYKPVDYQQLRALTEAKKLASASAKL-KIRKAMLTSKLSKEQTLIKQHKQVW 73
++ E+ + K Q L+ +A K + +L K ++ +TSK+ + Q L+K ++
Sbjct: 817 LEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEE-- 874
Query: 74 WQEYQRLNEVRCKMESEIKSLLNEENIGNECLCDLTNFEQELSEQQCTYLKNVINPIQQL 133
++N ++ +E + K L N + Q+L E+ + L
Sbjct: 875 -----QMNTMKAVLEEKEKDLANTGK-----------WLQDLQEEN-----------ESL 907
Query: 134 RADLKYRQHHTLQHSHPHIEFNSMKVLEEVDFVKKQLKTVFERLRLEQQRIENDLSDWSI 193
+A ++ H L+ E +S EE++ V K+ + +RL + E+DLS +
Sbjct: 908 KAHVQEVAQHNLK------EASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQ 961
Query: 194 KILDHSLEEKT-----NPLSELPIELESLECPYPDLKSSILSEFYKFTQKYQKKLQDFNL 248
+ D E K L + + S P+ +L ++SE K +L
Sbjct: 962 LLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLK-VISEREKEISGLWNELDSLKD 1020
Query: 249 QLEDIYRNCQLSEEDHW-------IYQAILDQYPGDLFGRRTLYLD--------MLQRYF 293
+E + E +W + +L R ++ +L++ F
Sbjct: 1021 AVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKERQQQVEAVELEAKEVLKKLF 1080
Query: 294 PHKS----------RHDLVEHEKYCDQYRFAIEQQNILISNWNKNRKDFIQKAVLTLTEA 343
P S H + K C E+ +L K+ + L E
Sbjct: 1081 PKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKVL----EHKLKEADEMHTLLQLEC 1136
Query: 344 CATHEMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKLW 403
+ +S+LA+ + Q+L ++ + +W+ +E + ++ + E+E E+L
Sbjct: 1137 ---EKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLR 1193
Query: 404 ---KKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQ-RLEELKKLIAEQSLKDRERVK 459
K E L+R + +++ A+ ++ E+R+L+ L EL+K + + S + R
Sbjct: 1194 SENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTELQKKL-DDSYSEAVRQN 1252
Query: 460 YRQELLERRLMEKKEVALQEAHEDKERARRLEALRKQVAVVAQFDPVRMMSDT 512
LL+ +L E E +E ++ A L ++ + ++ Q V+ DT
Sbjct: 1253 EELNLLKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELI-QSKIVKAAGDT 1304
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 60.1 bits (144), Expect = 6e-09
Identities = 117/572 (20%), Positives = 238/572 (41%), Gaps = 97/572 (16%)
Query: 9 DNLVFHMKNEMRNIKYKPVDYQQLRALTEAKKLASASAKLKIRKAMLTSK---------- 58
D L K E+ + ++ + +L A + A+ ++ + M+T K
Sbjct: 317 DALKKSSKGELTTLIHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMTEKERSNVVITRM 376
Query: 59 ------LSKEQTLIKQHKQVWWQEYQRLN----EVRCKMESEIKSLLNEENIGNECLCDL 108
L KE + + V +QE Q++ +VR +ME+EI L E I + + +
Sbjct: 377 KDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNT 436
Query: 109 TN-FEQELSEQQCTYLKNVINPIQQLRADLKYRQHHTLQHSHPHIEFNSMKV-LEEVDFV 166
TN E + S + ++ + +L Q +Q + +KV L+E +
Sbjct: 437 TNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAERR 496
Query: 167 KKQLKTVFERLRLEQQRIENDLSDWSIKILDHSLEEKTNPLSELPIELESLECPYPDLKS 226
+++++ + E + + DL ++ ++ + L++ + + LE
Sbjct: 497 WEEVQSYIRKRTAEHEAAQQDLQS-KFVAKENEVQSLHSKLTDTLVSKQQLE-------- 547
Query: 227 SILSEFYKFTQKYQKKLQDFNLQLEDIYRNCQLSEEDHWIYQAILDQYPGDLFGR--RTL 284
L + + QK K + +Q++DI E + +A + Q+ + + ++
Sbjct: 548 QRLMQLMESEQKRVNKEESLQMQVQDIL-------EQNEALKAQIQQFHSQIAAQTSASV 600
Query: 285 YLDMLQRYFPHKSRH-DLVEHEKYCDQYRFAIEQQNIL-ISNWNKNRKDFIQK-AVLTLT 341
+ L + K + E ++ R +++ + I N N K +QK L
Sbjct: 601 LAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANE 660
Query: 342 EACATHEME----SMLAKDKK---KQQELCADLKAKVRQW-------RAHQEEVARLEME 387
+A A HE+E S+ KD K +++L ++ K+ ++ +A + EV +L+
Sbjct: 661 QAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTL 720
Query: 388 IS-------ARRREK--EEEKEKLWKKKELLQ----------------RAEKKKKIKKYW 422
+S + EK +E+ EKL +ELL+ R E K+
Sbjct: 721 VSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQ 780
Query: 423 AKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQELLERRLME--KKEVALQEA 480
K ++ ++ L +EELKK+I E+ K +K +ELLE L++ KE +Q+
Sbjct: 781 DLKAKQNDQVSFASL--VEELKKVIHEKDGK----IKSVEELLEAELLKVANKEKTVQDL 834
Query: 481 HEDKERARRLEALRKQVAVVAQFDPVRMMSDT 512
++ ++AL++++ V Q + + +S T
Sbjct: 835 KQE------IKALKEEIGNV-QLEKAQQLSIT 859
Score = 44.7 bits (104), Expect = 2e-04
Identities = 100/517 (19%), Positives = 209/517 (40%), Gaps = 45/517 (8%)
Query: 12 VFHMKNE---MRNIKYKPVDYQQLRALTEAKKLASASAKLKIRKAMLTSKLSKEQTLIKQ 68
+ H+K E +R+ + + + E KL A+L T KL +E+ K
Sbjct: 419 IAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKN 478
Query: 69 HKQVWWQEYQRLNEVRCKMESEIKSLLNEENIGNECLCDLTNFEQELSEQQCTYLKNVIN 128
+Q Q +L E + E E++S + + +E + E + L + +
Sbjct: 479 AEQAATQLKVQLQEAERRWE-EVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLT 537
Query: 129 PIQQLRADLKYRQHHTLQHSHPHIEFNSMKVLEEVDFVKKQLKTVFERLRLEQQRIENDL 188
+ L+ R ++ + ++ D +++ E L+ + Q+ + +
Sbjct: 538 DTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQN-----EALKAQIQQFHSQI 592
Query: 189 S-DWSIKILDHSLEEKTNPLSELPIELESLECPYPDLKSSILSEFYKFTQKYQ--KKLQD 245
+ S +L EE ++E +++ E S+ SE + T K + K +Q+
Sbjct: 593 AAQTSASVL---AEELHKVIAEKDKQIKQTE-------DSLASERDRLTSKEEELKDIQN 642
Query: 246 FNLQLEDIYRNCQLSEEDHWIYQAILDQYPGDLFGRRTLYLDMLQRYFPHKSRHDLVEHE 305
N L+ + Q + L++ ++ + + +L+ H+ + + E +
Sbjct: 643 MNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDK-IRLLEEQLQHEISNKMEEFK 701
Query: 306 KYCDQ---YRFAIEQQNILISNW-NKNRKDFIQKAVLTLTEACATHE--MESMLAKDKKK 359
DQ + +++ L+S NK+ + ++K + E T E +E+ L + K
Sbjct: 702 ILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATK 761
Query: 360 QQELCA-------------DLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKLWKKK 406
++EL A DLKAK + V L+ I + + + +E L +
Sbjct: 762 EEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELL--EA 819
Query: 407 ELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQELLE 466
ELL+ A K+K ++ + K +E+ L++ ++L Q L++ + K Q
Sbjct: 820 ELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTM 879
Query: 467 RRLMEKKEVALQEAHE-DKERARRLEALRKQVAVVAQ 502
+ ++E+KE L + ++ E+L+ V VAQ
Sbjct: 880 KAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQ 916
Score = 41.6 bits (96), Expect = 0.002
Identities = 112/600 (18%), Positives = 250/600 (41%), Gaps = 82/600 (13%)
Query: 10 NLVFHMKNEMRNIKYKPVDYQQLRALTEAKKLASA----SAKLKIRKAMLTSKLSKEQTL 65
N+ F +K E++ K + + +Q A E +K+ + K+++ + L ++S +
Sbjct: 642 NMNFLLKAEVQ--KLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKM-- 697
Query: 66 IKQHKQVWWQEYQRLNEVRCKMESEIKSL--LNEENIGNECLCDLTNFEQELSEQQCTYL 123
+E++ LN+ ++SE++ L L E + + + QE E+ L
Sbjct: 698 ---------EEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEK----L 744
Query: 124 KNVINPIQQ--LRADLKYRQHHTLQHSHPHIEFNSMKVLEEVDFVKKQLKTV-FERLRLE 180
K V ++ ++ K + + ++ NS E D KQ V F L E
Sbjct: 745 KTVEELLETGLIQVATKEEELNAIRTE------NSSLTKEVQDLKAKQNDQVSFASLVEE 798
Query: 181 QQRIENDLSDWSIKILDHSLEEKTNPLSELPIELESLECPYPDLKSSILSEFYKFTQKYQ 240
+++ ++ D IK ++ LE + +++ + E DLK I + +
Sbjct: 799 LKKVIHE-KDGKIKSVEELLEAEL-------LKVANKEKTVQDLKQEIKALKEEIGNVQL 850
Query: 241 KKLQDFNL--QLEDIYRNCQLSEEDHWIYQAILDQYPGDLFGRRTLYLDMLQRYFPHKSR 298
+K Q ++ +++++ + EE +A+L++ DL D+ + K+
Sbjct: 851 EKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAH 910
Query: 299 -HDLVEHEKYCDQYRFAIEQQNILISNWNKNRKDFIQKAVLTLTEACATHEMESMLAKDK 357
++ +H E+ I++ K +++ +++ L E + ++ L +D
Sbjct: 911 VQEVAQHNLKEASSASQFEELEIVL----KEKENELKRLEAMLKERESDLSSKTQLLQDV 966
Query: 358 KKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKLWKKKELLQRAEKKKK 417
+ + +L +++Q Q E+ E+E+E LW + + L+ A + ++
Sbjct: 967 QDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQR 1026
Query: 418 IKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQEL--LERRLME---- 471
K ++ Q++E +L+ E LKKL + S+ + Y + L E++ E
Sbjct: 1027 -----KKNNERQQQVEAVELEAKEVLKKLFPKVSVP--SNLSYGEWLHGFEKKAKECMAG 1079
Query: 472 ---KKEVALQEAHEDKERARRLEALR----KQVAVVAQFDPV--RMMSDTMASKARMGIE 522
+EV + E H+ KE L+ K +V+A+ + + ++ + + ++
Sbjct: 1080 TSGSEEVKVLE-HKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVK 1138
Query: 523 IEEEFILQKPLFTLNTYNEQQI------------ISDPRLRFELALREAGLHRTLYAKEI 570
++E K + + T +EQ++ + R E+ L +A + R+ Y E+
Sbjct: 1139 VDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRREREHLEMELEKAEMERSTYVTEV 1198
Score = 37.4 bits (85), Expect = 0.039
Identities = 92/485 (18%), Positives = 195/485 (40%), Gaps = 87/485 (17%)
Query: 15 MKNEMRNIKYKPVDYQQLRALTEAKKLASASAKL-KIRKAMLTSKLSKEQTLIKQHKQVW 73
++ E+ + K Q L+ +A K + +L K ++ +TSK+ + Q L+K ++
Sbjct: 817 LEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEE-- 874
Query: 74 WQEYQRLNEVRCKMESEIKSLLNEENIGNECLCDLTNFEQELSEQQCTYLKNVINPIQQL 133
++N ++ +E + K L N + Q+L E+ + L
Sbjct: 875 -----QMNTMKAVLEEKEKDLANTGK-----------WLQDLQEEN-----------ESL 907
Query: 134 RADLKYRQHHTLQHSHPHIEFNSMKVLEEVDFVKKQLKTVFERLRLEQQRIENDLSDWSI 193
+A ++ H L+ E +S EE++ V K+ + +RL + E+DLS +
Sbjct: 908 KAHVQEVAQHNLK------EASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQ 961
Query: 194 KILDHSLEEKTNPLSELPIELESLECPYPDLKSSIL--SEFYKFTQKYQKKLQDFNLQLE 251
+ D E K ++E L+ SS E K + +K++ +L+
Sbjct: 962 LLQDVQDENKL-----FKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELD 1016
Query: 252 DI-----YRNCQLSEEDHWIYQAILDQYPGDLFGRRTLYLDMLQRYFPHKS--------- 297
+ ++ + +E + L+ ++L++ FP S
Sbjct: 1017 SLKDAVEHQRKKNNERQQQVEAVELEAK------------EVLKKLFPKVSVPSNLSYGE 1064
Query: 298 -RHDLVEHEKYCDQYRFAIEQQNILISNWNKNRKDFIQKAVLTLTEACATHEMESMLAKD 356
H + K C E+ +L K+ + L E + +S+LA+
Sbjct: 1065 WLHGFEKKAKECMAGTSGSEEVKVL----EHKLKEADEMHTLLQLEC---EKYKSVLAET 1117
Query: 357 KKKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKLW---KKKELLQRAE 413
+ Q+L ++ + +W+ +E + ++ + E+E E+L K E L+R
Sbjct: 1118 EGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRRER 1177
Query: 414 KKKKIKKYWAKKKQKWQEMEMRDL--QRLEELKKLIAEQSLK-----DRERVKYRQELLE 466
+ +++ A+ ++ E+R+L Q E L KL EQ+ + D + + EL++
Sbjct: 1178 EHLEMELEKAEMERSTYVTEVRELKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQ 1237
Query: 467 RRLME 471
++++
Sbjct: 1238 SKIVK 1242
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.131 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,162,602
Number of Sequences: 37866
Number of extensions: 969120
Number of successful extensions: 16722
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 329
Number of HSP's successfully gapped in prelim test: 919
Number of HSP's that attempted gapping in prelim test: 6990
Number of HSP's gapped (non-prelim): 5075
length of query: 591
length of database: 18,247,518
effective HSP length: 108
effective length of query: 483
effective length of database: 14,157,990
effective search space: 6838309170
effective search space used: 6838309170
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.