BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|31317239 interleukin 22 receptor, alpha 1 [Homo sapiens] (574 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|31317239 interleukin 22 receptor, alpha 1 [Homo sapiens] 1179 0.0 gi|31317241 interleukin 22-binding protein isoform 2 [Homo sapiens] 103 6e-22 gi|16418459 interleukin 22-binding protein isoform 1 [Homo sapiens] 87 5e-17 gi|31317243 interleukin 22-binding protein isoform 3 [Homo sapiens] 83 6e-16 gi|31083156 interleukin 20 receptor, alpha [Homo sapiens] 80 4e-15 gi|46488932 interferon-alpha receptor 1 precursor [Homo sapiens] 51 3e-06 gi|31324577 molecule interacting with Rab13 [Homo sapiens] 50 7e-06 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 47 6e-05 gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] 45 1e-04 gi|4503641 coagulation factor III precursor [Homo sapiens] 45 2e-04 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 44 4e-04 gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 44 4e-04 gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 44 4e-04 gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 44 4e-04 gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 44 4e-04 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 44 5e-04 gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 42 0.001 gi|110832843 TBP-associated factor 4 [Homo sapiens] 42 0.002 gi|163965366 nascent polypeptide-associated complex alpha subuni... 42 0.002 gi|15721939 metastatic lymph node 51 [Homo sapiens] 42 0.002 gi|222136575 interleukin 10 receptor, alpha precursor [Homo sapi... 41 0.003 gi|47419934 interferon gamma receptor 2 precursor [Homo sapiens] 41 0.003 gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 41 0.003 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 41 0.003 gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo s... 41 0.003 gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo sa... 41 0.003 gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 41 0.003 gi|19924099 synapsin I isoform Ia [Homo sapiens] 41 0.003 gi|19924097 synapsin I isoform Ib [Homo sapiens] 41 0.003 gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens] 40 0.004 >gi|31317239 interleukin 22 receptor, alpha 1 [Homo sapiens] Length = 574 Score = 1179 bits (3051), Expect = 0.0 Identities = 574/574 (100%), Positives = 574/574 (100%) Query: 1 MRTLLTILTVGSLAAHAPEDPSDLLQHVKFQSSNFENILTWDSGPEGTPDTVYSIEYKTY 60 MRTLLTILTVGSLAAHAPEDPSDLLQHVKFQSSNFENILTWDSGPEGTPDTVYSIEYKTY Sbjct: 1 MRTLLTILTVGSLAAHAPEDPSDLLQHVKFQSSNFENILTWDSGPEGTPDTVYSIEYKTY 60 Query: 61 GERDWVAKKGCQRITRKSCNLTVETGNLTELYYARVTAVSAGGRSATKMTDRFSSLQHTT 120 GERDWVAKKGCQRITRKSCNLTVETGNLTELYYARVTAVSAGGRSATKMTDRFSSLQHTT Sbjct: 61 GERDWVAKKGCQRITRKSCNLTVETGNLTELYYARVTAVSAGGRSATKMTDRFSSLQHTT 120 Query: 121 LKPPDVTCISKVRSIQMIVHPTPTPIRAGDGHRLTLEDIFHDLFYHLELQVNRTYQMHLG 180 LKPPDVTCISKVRSIQMIVHPTPTPIRAGDGHRLTLEDIFHDLFYHLELQVNRTYQMHLG Sbjct: 121 LKPPDVTCISKVRSIQMIVHPTPTPIRAGDGHRLTLEDIFHDLFYHLELQVNRTYQMHLG 180 Query: 181 GKQREYEFFGLTPDTEFLGTIMICVPTWAKESAPYMCRVKTLPDRTWTYSFSGAFLFSMG 240 GKQREYEFFGLTPDTEFLGTIMICVPTWAKESAPYMCRVKTLPDRTWTYSFSGAFLFSMG Sbjct: 181 GKQREYEFFGLTPDTEFLGTIMICVPTWAKESAPYMCRVKTLPDRTWTYSFSGAFLFSMG 240 Query: 241 FLVAVLCYLSYRYVTKPPAPPNSLNVQRVLTFQPLRFIQEHVLIPVFDLSGPSSLAQPVQ 300 FLVAVLCYLSYRYVTKPPAPPNSLNVQRVLTFQPLRFIQEHVLIPVFDLSGPSSLAQPVQ Sbjct: 241 FLVAVLCYLSYRYVTKPPAPPNSLNVQRVLTFQPLRFIQEHVLIPVFDLSGPSSLAQPVQ 300 Query: 301 YSQIRVSGPREPAGAPQRHSLSEITYLGQPDISILQPSNVPPPQILSPLSYAPNAAPEVG 360 YSQIRVSGPREPAGAPQRHSLSEITYLGQPDISILQPSNVPPPQILSPLSYAPNAAPEVG Sbjct: 301 YSQIRVSGPREPAGAPQRHSLSEITYLGQPDISILQPSNVPPPQILSPLSYAPNAAPEVG 360 Query: 361 PPSYAPQVTPEAQFPFYAPQAISKVQPSSYAPQATPDSWPPSYGVCMEGSGKDSPTGTLS 420 PPSYAPQVTPEAQFPFYAPQAISKVQPSSYAPQATPDSWPPSYGVCMEGSGKDSPTGTLS Sbjct: 361 PPSYAPQVTPEAQFPFYAPQAISKVQPSSYAPQATPDSWPPSYGVCMEGSGKDSPTGTLS 420 Query: 421 SPKHLRPKGQLQKEPPAGSCMLGGLSLQEVTSLAMEESQEAKSLHQPLGICTDRTSDPNV 480 SPKHLRPKGQLQKEPPAGSCMLGGLSLQEVTSLAMEESQEAKSLHQPLGICTDRTSDPNV Sbjct: 421 SPKHLRPKGQLQKEPPAGSCMLGGLSLQEVTSLAMEESQEAKSLHQPLGICTDRTSDPNV 480 Query: 481 LHSGEEGTPQYLKGQLPLLSSVQIEGHPMSLPLQPPSRPCSPSDQGPSPWGLLESLVCPK 540 LHSGEEGTPQYLKGQLPLLSSVQIEGHPMSLPLQPPSRPCSPSDQGPSPWGLLESLVCPK Sbjct: 481 LHSGEEGTPQYLKGQLPLLSSVQIEGHPMSLPLQPPSRPCSPSDQGPSPWGLLESLVCPK 540 Query: 541 DEAKSPAPETSDLEQPTELDSLFRGLALTVQWES 574 DEAKSPAPETSDLEQPTELDSLFRGLALTVQWES Sbjct: 541 DEAKSPAPETSDLEQPTELDSLFRGLALTVQWES 574 >gi|31317241 interleukin 22-binding protein isoform 2 [Homo sapiens] Length = 231 Score = 103 bits (256), Expect = 6e-22 Identities = 66/190 (34%), Positives = 93/190 (48%), Gaps = 4/190 (2%) Query: 26 QHVKFQSSNFENILTWDSGPEGTPDT-VYSIEYKTYGERDWVAKKGCQRITRKSCNLTVE 84 Q V+FQS NF NIL W G T ++ VY ++YK YG+R W K+ C SC+LT E Sbjct: 32 QRVQFQSRNFHNILQWQPGRALTGNSSVYFVQYKIYGQRQWKNKEDCWGTQELSCDLTSE 91 Query: 85 TGNLTELYYARVTAVSAGGRSATKMTDRFSSLQHTTLKPPDVTCISKVRSIQMIVHPTPT 144 T ++ E YY RV A SAG S MT RF+ T + PP + S+ +I+H Sbjct: 92 TSDIQEPYYGRVRAASAGSYSEWSMTPRFTPWWETKIDPPVMNITQVNGSLLVILHAPNL 151 Query: 145 PIRAGDGHRLTLEDIFHDLFYHLELQVN--RTYQMHLGGKQREYEFFGLTPDTEFLGTIM 202 P R +++ED +++L Y + + N Q G R E LTP + + Sbjct: 152 PYRYQKEKNVSIED-YYELLYRVFIINNSLEKEQKVYEGAHRAVEIEALTPHSSYCVVAE 210 Query: 203 ICVPTWAKES 212 I P + S Sbjct: 211 IYQPMLDRRS 220 >gi|16418459 interleukin 22-binding protein isoform 1 [Homo sapiens] Length = 263 Score = 86.7 bits (213), Expect = 5e-17 Identities = 66/222 (29%), Positives = 93/222 (41%), Gaps = 36/222 (16%) Query: 26 QHVKFQSSNFENILTWDSGPEGTPDT-VYSIEYKT------------------------- 59 Q V+FQS NF NIL W G T ++ VY ++YK Sbjct: 32 QRVQFQSRNFHNILQWQPGRALTGNSSVYFVQYKIMFSCSMKSSHQKPSGCWQHISCNFP 91 Query: 60 -------YGERDWVAKKGCQRITRKSCNLTVETGNLTELYYARVTAVSAGGRSATKMTDR 112 YG+R W K+ C SC+LT ET ++ E YY RV A SAG S MT R Sbjct: 92 GCRTLAKYGQRQWKNKEDCWGTQELSCDLTSETSDIQEPYYGRVRAASAGSYSEWSMTPR 151 Query: 113 FSSLQHTTLKPPDVTCISKVRSIQMIVHPTPTPIRAGDGHRLTLEDIFHDLFYHLELQVN 172 F+ T + PP + S+ +I+H P R +++ED +++L Y + + N Sbjct: 152 FTPWWETKIDPPVMNITQVNGSLLVILHAPNLPYRYQKEKNVSIED-YYELLYRVFIINN 210 Query: 173 --RTYQMHLGGKQREYEFFGLTPDTEFLGTIMICVPTWAKES 212 Q G R E LTP + + I P + S Sbjct: 211 SLEKEQKVYEGAHRAVEIEALTPHSSYCVVAEIYQPMLDRRS 252 >gi|31317243 interleukin 22-binding protein isoform 3 [Homo sapiens] Length = 130 Score = 83.2 bits (204), Expect = 6e-16 Identities = 43/90 (47%), Positives = 54/90 (60%), Gaps = 1/90 (1%) Query: 26 QHVKFQSSNFENILTWDSGPEGTPDT-VYSIEYKTYGERDWVAKKGCQRITRKSCNLTVE 84 Q V+FQS NF NIL W G T ++ VY ++YK YG+R W K+ C SC+LT E Sbjct: 32 QRVQFQSRNFHNILQWQPGRALTGNSSVYFVQYKIYGQRQWKNKEDCWGTQELSCDLTSE 91 Query: 85 TGNLTELYYARVTAVSAGGRSATKMTDRFS 114 T ++ E YY RV A SAG S MT RF+ Sbjct: 92 TSDIQEPYYGRVRAASAGSYSEWSMTPRFT 121 >gi|31083156 interleukin 20 receptor, alpha [Homo sapiens] Length = 553 Score = 80.5 bits (197), Expect = 4e-15 Identities = 62/240 (25%), Positives = 112/240 (46%), Gaps = 16/240 (6%) Query: 27 HVKFQSSNFENILTWDSGPEGTPDT--VYSIEYKTYGERDWVAKKGCQRITRKSCNLTVE 84 ++ F S N +N+L W + PEG Y+++Y YG++ W+ K C+ I R C+L+ E Sbjct: 42 NITFLSINMKNVLQW-TPPEGLQGVKVTYTVQYFIYGQKKWLNKSECRNINRTYCDLSAE 100 Query: 85 TGNLTELYYARVTAVSAGGRSATKMTDRFSSLQHTTLKPPDVTCISKVRSIQMIVHPTPT 144 T + YYA+V A+ S + RF T + PP+V + +SI +++ Sbjct: 101 TSDYEHQYYAKVKAIWGTKCSKWAESGRFYPFLETQIGPPEVALTTDEKSISVVLTAPEK 160 Query: 145 PIRAGDGHRLTLEDIFHDLFYH---LELQVNRTYQMHLGGKQREYEFFGLTPDTEFLGTI 201 R + ++++ I+ +L Y+ L + NRT+ + L P+T + + Sbjct: 161 WKRNPEDLPVSMQQIYSNLKYNVSVLNTKSNRTWSQCV--TNHTLVLTWLEPNTLYCVHV 218 Query: 202 MICVPTWAKESAP--YMCRVKTLPDRTWTYSFSGAFLFSMG-----FLVAVLCYLSYRYV 254 VP + + P C +TL D++ + F + + FL +V+ Y YRY+ Sbjct: 219 ESFVPGPPRRAQPSEKQC-ARTLKDQSSEFKAKIIFWYVLPVSITVFLFSVMGYSIYRYI 277 >gi|46488932 interferon-alpha receptor 1 precursor [Homo sapiens] Length = 557 Score = 50.8 bits (120), Expect = 3e-06 Identities = 38/164 (23%), Positives = 71/164 (43%), Gaps = 15/164 (9%) Query: 38 ILTWDSGPEGTPDTVYSIEYKTYGERDWVAKKGCQRITRKSCNLTVETGNLTELYYARVT 97 IL W+ E + +S +Y+ G +W+ GCQ IT CN + N+ E R+ Sbjct: 46 ILRWNRSDESVGNVTFSFDYQKTGMDNWIKLSGCQNITSTKCNFSSLKLNVYEEIKLRIR 105 Query: 98 AVSAGGRSATKMTDRFSSLQHTTLKPPDVTCISKVRSIQMIVHPTP----TPIRAGDGHR 153 A S+ D F+ + + PP+V ++ ++I ++H +P + + A DG Sbjct: 106 A-EKENTSSWYEVDSFTPFRKAQIGPPEVHLEAEDKAI--VIHISPGTKDSVMWALDGLS 162 Query: 154 LTLEDIFHDLFYHLELQVNRTYQMHLGGKQREYEFFGLTPDTEF 197 T + +E ++ Y H + + L+P+T + Sbjct: 163 FTYSLVIWKNSSGVEERIENIYSRH--------KIYKLSPETTY 198 >gi|31324577 molecule interacting with Rab13 [Homo sapiens] Length = 863 Score = 49.7 bits (117), Expect = 7e-06 Identities = 85/337 (25%), Positives = 129/337 (38%), Gaps = 65/337 (19%) Query: 258 PAPPNSLNVQRVLTFQPLRFIQEHVLIPVFDLSGPSSLAQPVQYSQIRVSGPREPAGAPQ 317 PAPP T +P +Q+ L+ + +G SSL + ++ V PR G P+ Sbjct: 314 PAPP---------TPRPRSSLQQENLV---EQAGSSSLVNG-RLHELPVPKPR---GTPK 357 Query: 318 RHSLSEITYLGQPDISILQ-----------PSNVPPPQILSPLSYAPNAAPEVGPPSYAP 366 + P I+++Q PS+ P P EV PS Sbjct: 358 PSEGTPAPRKDPPWITLVQAEPKKKPAPLPPSSSPGPPSQDSRQVENGGTEEVAQPSPTA 417 Query: 367 QVTPEAQFPFY---------APQAIS-KVQPSSYAPQATPDSWPPSYGVCMEGSGK---- 412 + + PF AP A S P+ P++TP S P YG+ S K Sbjct: 418 SLESKPYNPFEEEEEDKEEEAPAAPSLATSPALGHPESTPKSLHPWYGITPTSSPKTKKR 477 Query: 413 DSPTGTLSSPKHLRPKGQLQKEPPAGSCMLGGLSLQEVTSLAMEESQEAKSLHQPLGICT 472 +P +SP L EPP+ + LS++ ++S + ++ A+ L P Sbjct: 478 PAPRAPSASPLALHASRLSHSEPPSAT-PSPALSVESLSSESASQTAGAELLEPP--AVP 534 Query: 473 DRTSDPNVLHSGEEGTPQYLKGQLPLLSS-----VQIEGHPMSLP-LQP---------PS 517 +S+P V G G P L L SS ++E P + P L P P+ Sbjct: 535 KSSSEPAVHAPGTPGNPVSLSTNSSLASSGELVEPRVEQMPQASPGLAPRTRGSSGPQPA 594 Query: 518 RPCSPSDQGPSPWGLLESLVCPKDEAKSPAPETSDLE 554 +PCS G +P LL LV + SP + L+ Sbjct: 595 KPCS----GATPTPLL--LVGDRSPVPSPGSSSPQLQ 625 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 46.6 bits (109), Expect = 6e-05 Identities = 80/284 (28%), Positives = 107/284 (37%), Gaps = 46/284 (16%) Query: 305 RVSGPREPAGAPQRHSLSEITYLGQPDISILQP----SNVPPPQILSPLSYAPNAAPEVG 360 R+S P P +P E P+ S L P S + PP SPLS P A+ Sbjct: 571 RLSPP--PEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSP 628 Query: 361 PPSYAPQVTPEAQFPFYAPQAISKVQP------SSYAPQATPDSWPPSYGVCM---EGSG 411 PP +P P + P P +S++ P S P+ +P S PP E S Sbjct: 629 PPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASR 688 Query: 412 KDSPTGTLSSPKHLRPKGQLQKEPPAGSCMLGGLSLQEVTSLAM-EESQEAKSLHQPLGI 470 P SP P+ PP S M L L+E L + EE Q P Sbjct: 689 LSPPPE--DSPTSPPPEDSPASPPPEDSLM--SLPLEESPLLPLPEEPQLCPRSEGP--H 742 Query: 471 CTDRTSDPNVLHSGEEG--TPQYLKGQL------PLLSSVQIEGH--PMS----LPLQPP 516 + R +P++ EE +PQ + L P L +V E H P + L QP Sbjct: 743 LSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPE 802 Query: 517 SRPCSPSDQGP--SPWGLLESLVCPKDEAKSPAPETSDLEQPTE 558 SP + P SP P++ SP PE S L +E Sbjct: 803 ELHLSPQTEEPHLSP--------VPEEPCLSPQPEESHLSPQSE 838 Score = 42.7 bits (99), Expect = 9e-04 Identities = 64/235 (27%), Positives = 84/235 (35%), Gaps = 27/235 (11%) Query: 341 PPPQILSPLSYAPNAAPEVGPPSYAPQVTPEAQFPFYAPQAISKVQPSSYAPQATPDSWP 400 PPP+ L P S P A P +P P + P P S P +P + P+ P Sbjct: 469 PPPEEL-PASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESP 527 Query: 401 PSYGVCMEGSGKDSPTGTLSSPKHLR-----PKGQLQKEPPAGSCMLGGLSLQEVTSLAM 455 PS +E P + SP P +L PP + L + S Sbjct: 528 PS--PALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPP 585 Query: 456 EES-----QEAKSLHQPLGICTDRTSDPNVLHSGEEGTPQYLKGQLPLLSSVQIEGHPMS 510 EES EA L P + + L E +P + LS E PMS Sbjct: 586 EESPMSPPPEASRLFPPF--------EESPLSPPPEESPLSPPPEASRLSPPP-EDSPMS 636 Query: 511 LPLQPPSRPCSPSDQGP--SPWGLLESLVCPKDEAK-SPAPETSDLEQPTELDSL 562 P P P SP + SP ++ L P +E+ SP PE S P E L Sbjct: 637 PP--PEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRL 689 Score = 38.9 bits (89), Expect = 0.013 Identities = 65/260 (25%), Positives = 89/260 (34%), Gaps = 58/260 (22%) Query: 309 PREPAGAPQRHSLSEITYLGQPDISIL--QPSNVPPPQILSPLSYAPNAAP--EVGPPSY 364 P EP P L G+P +S L +P+ P + PLS P P G PS Sbjct: 868 PEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGE--PPLSPLPEELPLSPSGEPSL 925 Query: 365 APQVTPEAQFPFYAPQAISKVQPSSYAPQATPDSWPPSYGVCMEGSGKDSPTGTLSSPKH 424 +PQ+ P PD PP SP T ++P Sbjct: 926 SPQLMP-------------------------PDPLPPPL----------SPIITAAAPPA 950 Query: 425 LRPKGQLQKEPPAGSCMLGGLSLQEVTSLAMEESQEAKSLHQPLGICTDRTSDPNVLHSG 484 L P G+L+ G + S E P CTD P ++ Sbjct: 951 LSPLGELEYP-------FGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPP 1003 Query: 485 EEGTP-----QYLKGQLPLLSSVQIEGHPMSLPLQPPSRPCSPSD---QGPSPWGLLESL 536 G+P L LP S ++ H + PPS+ CSP PSP + + Sbjct: 1004 SPGSPVGPASPILMEPLPPQCSPLLQ-HSLVPQNSPPSQ-CSPPALPLSVPSPLSPIGKV 1061 Query: 537 VCPKDEAKSPAPETSDLEQP 556 V DEA+ ET + +P Sbjct: 1062 VGVSDEAELHEMETEKVSEP 1081 Score = 35.0 bits (79), Expect = 0.19 Identities = 51/225 (22%), Positives = 70/225 (31%), Gaps = 66/225 (29%) Query: 340 VPPPQILSPLSYAPNAAPEVGPPSYAPQVTPEAQFPFYA-PQAISKVQPSSYAPQATPDS 398 +PPP+ SPLS P +P PP + P + P P+A+ +P +P + P Sbjct: 441 LPPPEE-SPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPE 499 Query: 399 WPPSYGVCMEGSGKDSPTGTLSSPKHLRPKGQLQKEPPAGSCMLGGLSLQEVTSLAMEES 458 P LS P P L++ P + EES Sbjct: 500 ESP-----------------LSPPPESSPFSPLEESPLSPP----------------EES 526 Query: 459 QEAKSLHQPLGICTDRTSDPNVLHSGEEGTPQYLKGQLPLLSSVQIEGHPMSLPLQPPSR 518 + +L PL P P + P LP PP Sbjct: 527 PPSPALETPLS------------------PPPEASPLSPPFEESPLSPPPEELPTSPP-- 566 Query: 519 PCSPSDQGPSPWGLLESLVCPKDEAKSPAPETSDLEQPTELDSLF 563 P SP P++ SP PE S + P E LF Sbjct: 567 ---PEASRLSP--------PPEESPMSPPPEESPMSPPPEASRLF 600 Score = 34.7 bits (78), Expect = 0.24 Identities = 73/305 (23%), Positives = 105/305 (34%), Gaps = 43/305 (14%) Query: 257 PPAPPNSLNVQRVLTFQPLRFIQEHVLIPVFDLSGPSSLAQPVQYSQIRVSGPREPAGAP 316 P +PP + L PL +E P + + L+ P + S + P P Sbjct: 502 PLSPPPESSPFSPLEESPLSPPEESPPSPALE----TPLSPPPEASPLSPPFEESPLSPP 557 Query: 317 QRHSLSEITYLGQPDISILQPSNVPPPQILSPLSYAPNAAPEVGPPSYAPQVTPEAQFPF 376 E+ P+ S L P PP + SP+S P +P PP + P + P Sbjct: 558 PE----ELPTSPPPEASRLSP---PPEE--SPMSPPPEESPMSPPPEASRLFPPFEESPL 608 Query: 377 YAPQAISKVQPSSYAPQATPDSWPPSYGVCMEGSGKDSPTGTLSSPKHLRPKGQLQK-EP 435 P S + P A + + PP M ++SP L P + + P Sbjct: 609 SPPPEESPLSPPPEASRLS----PPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSP 664 Query: 436 PAGSCMLGGLSLQEVTSLAMEESQEAKSLHQPLGICTDRTSDPNVLHSGEEGTPQYLKGQ 495 P L + TS EA L P D + P S P+ Sbjct: 665 PPEESPLSPPPEESPTS----PPPEASRLSPP---PEDSPTSPPPEDSPASPPPE----- 712 Query: 496 LPLLSSVQIEGHPMSLPLQPPSRPCSPSDQGP--SPWGLLESLVCPKDEAKSPAPETSDL 553 L S+ +E P+ LPL + C P +GP SP P++ SP PE L Sbjct: 713 -DSLMSLPLEESPL-LPLPEEPQLC-PRSEGPHLSP--------RPEEPHLSPRPEEPHL 761 Query: 554 EQPTE 558 E Sbjct: 762 SPQAE 766 >gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] Length = 1003 Score = 45.4 bits (106), Expect = 1e-04 Identities = 66/267 (24%), Positives = 93/267 (34%), Gaps = 28/267 (10%) Query: 308 GPREPAGAPQRHSLSEITYLGQPDISILQPSNVPPPQILSP----LSYAPNA------AP 357 GP G P+ SL + L P +L P + PP +L+ L+ P A A Sbjct: 584 GPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAE 643 Query: 358 EVGPPSYAP-----QVTPEAQFPFYAPQAISKVQPSSYAPQATPDSWPPSYGVCMEGSGK 412 G PS P ++P P AP + + + A P S P + Sbjct: 644 GAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQP 703 Query: 413 DSPTGTLSSPKHLRPKGQLQKEPPAG-------SCMLGGLSLQEVTSLAMEESQEAKSLH 465 PT ++++ L K P S +LG L +++SL SL Sbjct: 704 GPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPG-ALPSLL 762 Query: 466 QPLGICTDRTSDPNVLHSGEEGTPQYLKGQLP---LLSSVQIEGHPMSLPLQPPSRPCSP 522 QP G +L G P + P LL S+QI P PP P S Sbjct: 763 QPPGPLLSGQLGLQLLPGG-GAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASA 821 Query: 523 SDQGPSPWGLLESLVCPKDEAKSPAPE 549 + P+ L +L P P PE Sbjct: 822 LEPEPAR-PPLSALAPPHGSPDPPVPE 847 Score = 31.6 bits (70), Expect = 2.1 Identities = 59/241 (24%), Positives = 83/241 (34%), Gaps = 32/241 (13%) Query: 335 LQPSNV----PPPQILSPLSYAPNAAPEV-GPPSYAPQVTPEAQFPFYAPQAISKVQPSS 389 L PSN P P P+S A P V GP AP V PF A +S + Sbjct: 272 LPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQ 331 Query: 390 YAPQATPDSWPPSYGVCMEGSGKDSPTGTLSSPKHLRPKGQLQKEPPAGSCMLGGLSLQE 449 + P P + ++G + + S LRP + + PP +L G Q Sbjct: 332 HPPLPPPST--------LQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQ- 382 Query: 450 VTSLAMEESQEAKSLHQPLGICTDRTSDP------NVLHSGEEGTPQYLKGQLPLLSSVQ 503 S+ P S P ++L G P + G LL S Sbjct: 383 ----TPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPG-PSHSDGSFNLLGSDA 437 Query: 504 IEGHPMSL----PLQPPSRPCSPSDQGPSPWGL--LESLVCPKDEAKSPAPETSDLEQPT 557 P +L P Q P P PS G + L + P +K+P + L+ P+ Sbjct: 438 HLPPPPTLSSGSPPQ-PRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPS 496 Query: 558 E 558 E Sbjct: 497 E 497 >gi|4503641 coagulation factor III precursor [Homo sapiens] Length = 295 Score = 44.7 bits (104), Expect = 2e-04 Identities = 47/177 (26%), Positives = 79/177 (44%), Gaps = 18/177 (10%) Query: 2 RTLLTILTVGSLAAHAPEDPSDLLQHVKFQSSNFENILTWDSGPEGTPDTVYSIEYKTYG 61 RTLL +A + + ++ ++S+NF+ IL W+ P + VY+++ T Sbjct: 18 RTLLLGWVFAQVAGASGTTNTVAAYNLTWKSTNFKTILEWEPKP---VNQVYTVQIST-K 73 Query: 62 ERDWVAKKGCQRITRKSCNLTVE-TGNLTELYYARVTAVSAGGRSAT--------KMTDR 112 DW +K C T C+LT E ++ + Y ARV + AG +T + + Sbjct: 74 SGDWKSK--CFYTTDTECDLTDEIVKDVKQTYLARVFSYPAGNVESTGSAGEPLYENSPE 131 Query: 113 FSSLQHTTLKPPDVTCISKV-RSIQMIVHPTPTPIRAGDGHRLTLEDIF-HDLFYHL 167 F+ T L P + +V + + V T +R + L+L D+F DL Y L Sbjct: 132 FTPYLETNLGQPTIQSFEQVGTKVNVTVEDERTLVRRNNTF-LSLRDVFGKDLIYTL 187 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 43.9 bits (102), Expect = 4e-04 Identities = 74/268 (27%), Positives = 92/268 (34%), Gaps = 51/268 (19%) Query: 290 SGPSSLAQPVQYSQIRVSGPREPAGAPQRHSLSEITYLGQPDISI---------LQPSNV 340 S P S + P + P PA P + + S LG P + L P Sbjct: 301 SAPPSPSAPPSLQTL----PSPPATPPSQATTS----LGSPTLQATHSFLPSPPLSPLAT 352 Query: 341 PPPQILSPLSYAPNAAPEVGP--PSYAPQVTPEAQFPFYAPQAISKVQPSSYAPQATPDS 398 PPPQ L+ P AP P P +P TP Q P A+ +Q AP + P S Sbjct: 353 PPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAP--NALAVHLLQ----APFSPPPS 406 Query: 399 WPPSYGVCMEGSGKDSPTGTLSS---PKHLRPKGQLQKEPPAGSCMLGGLSL--QEVTSL 453 P S SP+ T S P P Q+ PPA M + Q L Sbjct: 407 PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL 466 Query: 454 AMEESQEAKSLHQ-PLGICTDRTSDPNVLHSGEEGTPQYLKGQLPLLSSVQIEGHPMSLP 512 A Q AK Q P + T P GQ P S + P++ P Sbjct: 467 AAPPLQLAKPPPQAPPALATPPLQ-------ALPSPPASFPGQAPFSPSASLPMSPLATP 519 Query: 513 ------------LQ-PPSRPCSPSDQGP 527 LQ PPS P SP+ Q P Sbjct: 520 PPQAPPVLAAPLLQVPPSPPASPTLQAP 547 Score = 40.4 bits (93), Expect = 0.004 Identities = 47/163 (28%), Positives = 60/163 (36%), Gaps = 25/163 (15%) Query: 257 PPAPPNSLNVQRVLTFQPLRFIQEHVLIPVFDLSGPSSLAQPVQYSQIRVSGPREPAGAP 316 PP+PP S + + T P Q + V L P S P Q S P P +P Sbjct: 369 PPSPPASPPLSPLATPSP----QAPNALAVHLLQAPFS-PPPSPPVQAPFSPPASPPVSP 423 Query: 317 QRHSLSEIT-YLGQPDISI---------LQPSNVPPPQILSPLSYAP--------NAAPE 358 S+ L P + + + PS PPPQ PL+ P A P Sbjct: 424 SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPA 483 Query: 359 VGPPSYAPQVTPEAQFPFYAPQAISKVQPSSYAPQATPDSWPP 401 + P +P A FP AP + S P S P ATP P Sbjct: 484 LATPPLQALPSPPASFPGQAPFSPSASLPMS--PLATPPPQAP 524 Score = 37.7 bits (86), Expect = 0.029 Identities = 68/278 (24%), Positives = 92/278 (33%), Gaps = 51/278 (18%) Query: 290 SGPSSLAQPVQYSQIRVSGPREPAGAPQRHSLSEITYLGQPDISILQPSNVPPPQILSPL 349 S + L+ P + PR PA Q + L+P V PP+ Sbjct: 235 SSATPLSSPARSGPSARGTPRAPAHPSQPKPKG---------LQALRPPQVTPPR----- 280 Query: 350 SYAPNAAPEVGPPSYAPQVTPEAQFPFYAPQAISKVQPSSYAPQATPDSWPPSYGVCMEG 409 +AAP +GP S +P TP P +P A P S +P + PPS G Sbjct: 281 ---KDAAPALGPLSSSPLATPSPSAP-PSPSA-----PPSLQTLPSPPATPPSQATTSLG 331 Query: 410 SGKDSPTGT-LSSPKHLRPKGQLQKEPPAGSCMLGGLSLQEVTS---------LAMEESQ 459 S T + L SP P L PP L LQ S LA Q Sbjct: 332 SPTLQATHSFLPSP----PLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQ 387 Query: 460 --EAKSLHQPLGICTDRTSDP-NVLHSGEEGTPQYLKGQLPLLSSVQIEGHPMSLPLQPP 516 A ++H + S P S P P + + P+ +P PP Sbjct: 388 APNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 447 Query: 517 SRP-----CSPSDQGPSPWGLLESLVCPKDEAKSPAPE 549 + P +P Q P P L P + P P+ Sbjct: 448 ASPPMSPSATPPPQAPPP------LAAPPLQLAKPPPQ 479 Score = 30.4 bits (67), Expect = 4.6 Identities = 29/106 (27%), Positives = 39/106 (36%), Gaps = 14/106 (13%) Query: 306 VSGPREPA----GAPQRHSLSEITYLGQPDISILQPSNVPPPQILSPLSYAPNAAPEVGP 361 VSGPR G P S S + L PD++ S P+ L P P Sbjct: 559 VSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASP 618 Query: 362 PSYAPQVTPEAQFPFYAPQAISKVQPSSYAPQATPDS---WPPSYG 404 P P+A+ P A S+ A + P + WPP+ G Sbjct: 619 P-------PDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATG 657 >gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] Length = 2285 Score = 43.9 bits (102), Expect = 4e-04 Identities = 62/244 (25%), Positives = 84/244 (34%), Gaps = 36/244 (14%) Query: 292 PSSLAQPVQYSQIRVSGPREPAGAPQRHSLSEITYLGQPDISILQPSNVPPPQILSPLSY 351 P S P Q + S ++P P + S+ Y QP Q S P P S Sbjct: 484 PYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQ 543 Query: 352 APNAAPEVGPP---SYAPQVTPEAQFPFYAPQAISKVQPSSYAPQATPDS---WPPSYGV 405 P + P P S Q P+ P Q + QP S Q T S +PP + Sbjct: 544 HPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQEL 603 Query: 406 CMEGSGKDSPTGTLSSPKHLRPKGQLQKEPPAGSCMLGGLSLQEVTSLAMEESQEAKSLH 465 + G + S+P KG + LSLQ S + S L Sbjct: 604 SQDSFGSQAS----SAPSMTSSKGGQEDM---------NLSLQSRPSSLPDLSGSIDDL- 649 Query: 466 QPLGICTDRTSDPNVLHSGEEGTPQYLKGQLPLLSSVQIEGHPMSLPLQPPSRPCSPSDQ 525 P+G T+ P V SG + SS + +P P P + P P + Sbjct: 650 -PMG--TEGALSPGVSTSG-------------ISSSQGEQSNPAQSPFSPHTSPHLPGIR 693 Query: 526 GPSP 529 GPSP Sbjct: 694 GPSP 697 Score = 38.9 bits (89), Expect = 0.013 Identities = 64/252 (25%), Positives = 92/252 (36%), Gaps = 36/252 (14%) Query: 303 QIRVSGPREPAGAPQRHSLSEITYLGQPDISILQPSNVPPPQILSPLSYAPNAAPEVGPP 362 QI G + P+G Q+ + Y Q P PP P S P+A P Sbjct: 450 QIPPYGQQGPSGYGQQ---GQTPYYNQQSP---HPQQQQPPYSQQPPSQTPHA-----QP 498 Query: 363 SYAPQVTPEAQFP-FYAPQAISKVQPSSYAPQATPDSWPPSYGVCMEGSGKDSPTGTLSS 421 SY Q P++Q P + Q QPS Q +P +P + P S Sbjct: 499 SYQQQ--PQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPP---YSQ 553 Query: 422 PKHLRPKGQLQKEPPAGSCMLGGLSLQEVTSLAMEESQEAKSLHQPLGICTDRTSDPNVL 481 P+ P Q Q + PA S +L + + +SQ++ Q R P L Sbjct: 554 PQAQSPYQQQQPQQPAPS------TLSQQAAYPQPQSQQS----QQTAYSQQRFPPPQEL 603 Query: 482 HSGEEGTPQYLKGQLPLLSSVQIEGHPMSLPLQPPSRPCSPSDQGPSPWGLLESLVCPKD 541 G+ P ++S + M+L LQ SRP S D G ++ L + Sbjct: 604 SQDSFGSQ---ASSAPSMTSSKGGQEDMNLSLQ--SRPSSLPDLS----GSIDDLPMGTE 654 Query: 542 EAKSPAPETSDL 553 A SP TS + Sbjct: 655 GALSPGVSTSGI 666 >gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] Length = 2068 Score = 43.9 bits (102), Expect = 4e-04 Identities = 62/244 (25%), Positives = 84/244 (34%), Gaps = 36/244 (14%) Query: 292 PSSLAQPVQYSQIRVSGPREPAGAPQRHSLSEITYLGQPDISILQPSNVPPPQILSPLSY 351 P S P Q + S ++P P + S+ Y QP Q S P P S Sbjct: 484 PYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQ 543 Query: 352 APNAAPEVGPP---SYAPQVTPEAQFPFYAPQAISKVQPSSYAPQATPDS---WPPSYGV 405 P + P P S Q P+ P Q + QP S Q T S +PP + Sbjct: 544 HPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQEL 603 Query: 406 CMEGSGKDSPTGTLSSPKHLRPKGQLQKEPPAGSCMLGGLSLQEVTSLAMEESQEAKSLH 465 + G + S+P KG + LSLQ S + S L Sbjct: 604 SQDSFGSQAS----SAPSMTSSKGGQEDM---------NLSLQSRPSSLPDLSGSIDDL- 649 Query: 466 QPLGICTDRTSDPNVLHSGEEGTPQYLKGQLPLLSSVQIEGHPMSLPLQPPSRPCSPSDQ 525 P+G T+ P V SG + SS + +P P P + P P + Sbjct: 650 -PMG--TEGALSPGVSTSG-------------ISSSQGEQSNPAQSPFSPHTSPHLPGIR 693 Query: 526 GPSP 529 GPSP Sbjct: 694 GPSP 697 Score = 38.9 bits (89), Expect = 0.013 Identities = 64/252 (25%), Positives = 92/252 (36%), Gaps = 36/252 (14%) Query: 303 QIRVSGPREPAGAPQRHSLSEITYLGQPDISILQPSNVPPPQILSPLSYAPNAAPEVGPP 362 QI G + P+G Q+ + Y Q P PP P S P+A P Sbjct: 450 QIPPYGQQGPSGYGQQ---GQTPYYNQQSP---HPQQQQPPYSQQPPSQTPHA-----QP 498 Query: 363 SYAPQVTPEAQFP-FYAPQAISKVQPSSYAPQATPDSWPPSYGVCMEGSGKDSPTGTLSS 421 SY Q P++Q P + Q QPS Q +P +P + P S Sbjct: 499 SYQQQ--PQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPP---YSQ 553 Query: 422 PKHLRPKGQLQKEPPAGSCMLGGLSLQEVTSLAMEESQEAKSLHQPLGICTDRTSDPNVL 481 P+ P Q Q + PA S +L + + +SQ++ Q R P L Sbjct: 554 PQAQSPYQQQQPQQPAPS------TLSQQAAYPQPQSQQS----QQTAYSQQRFPPPQEL 603 Query: 482 HSGEEGTPQYLKGQLPLLSSVQIEGHPMSLPLQPPSRPCSPSDQGPSPWGLLESLVCPKD 541 G+ P ++S + M+L LQ SRP S D G ++ L + Sbjct: 604 SQDSFGSQ---ASSAPSMTSSKGGQEDMNLSLQ--SRPSSLPDLS----GSIDDLPMGTE 654 Query: 542 EAKSPAPETSDL 553 A SP TS + Sbjct: 655 GALSPGVSTSGI 666 >gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] Length = 2426 Score = 43.9 bits (102), Expect = 4e-04 Identities = 62/246 (25%), Positives = 93/246 (37%), Gaps = 29/246 (11%) Query: 297 QPVQY-SQIRVSGPREPAGAPQRHSLSEITYLGQPDISILQPSNVP-PPQILSPLSYAPN 354 QPV S+I S P P+ L + T L + S+ +P PP P P Sbjct: 342 QPVDVPSEIADSSMTRPQELPE---LPKTTALELQESSVASAMELPGPPATSMPELQGPP 398 Query: 355 AAPEVGPPSYAPQVTPEAQFPFYAPQAISKVQPSSYAPQATPDSWPPSYGVCMEGSGKDS 414 P + P + PE P P P++ P+ S P + E G + Sbjct: 399 VTPVLELPGPSATPVPELPGPLSTPVPELPGPPATAVPELPGPSVTPVPQLSQELPGLPA 458 Query: 415 PTGTLSSPKHLRPKGQLQKEPPAGSCMLGGLSL--QEVTSLAMEESQE---AKSLHQPLG 469 P+ L P+ + + +E P + + L Q ++AME +++ L QP+G Sbjct: 459 PSMGLEPPQEVPEPPVMAQELPGLPLVTAAVELPEQPAVTVAMELTEQPVTTTELEQPVG 518 Query: 470 ICTDRTSDPNVLHSG--EEGTPQYLKGQLPLLSSVQIEGHP-----MSLPLQP-----PS 517 + T V H G E T L GQ +++ G P + LP QP P Sbjct: 519 MTT-------VEHPGHPEVTTATGLLGQPEATMVLELPGQPVATTALELPGQPSVTGVPE 571 Query: 518 RPCSPS 523 P PS Sbjct: 572 LPGLPS 577 >gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] Length = 2303 Score = 43.9 bits (102), Expect = 4e-04 Identities = 62/246 (25%), Positives = 93/246 (37%), Gaps = 29/246 (11%) Query: 297 QPVQY-SQIRVSGPREPAGAPQRHSLSEITYLGQPDISILQPSNVP-PPQILSPLSYAPN 354 QPV S+I S P P+ L + T L + S+ +P PP P P Sbjct: 342 QPVDVPSEIADSSMTRPQELPE---LPKTTALELQESSVASAMELPGPPATSMPELQGPP 398 Query: 355 AAPEVGPPSYAPQVTPEAQFPFYAPQAISKVQPSSYAPQATPDSWPPSYGVCMEGSGKDS 414 P + P + PE P P P++ P+ S P + E G + Sbjct: 399 VTPVLELPGPSATPVPELPGPLSTPVPELPGPPATAVPELPGPSVTPVPQLSQELPGLPA 458 Query: 415 PTGTLSSPKHLRPKGQLQKEPPAGSCMLGGLSL--QEVTSLAMEESQE---AKSLHQPLG 469 P+ L P+ + + +E P + + L Q ++AME +++ L QP+G Sbjct: 459 PSMGLEPPQEVPEPPVMAQELPGLPLVTAAVELPEQPAVTVAMELTEQPVTTTELEQPVG 518 Query: 470 ICTDRTSDPNVLHSG--EEGTPQYLKGQLPLLSSVQIEGHP-----MSLPLQP-----PS 517 + T V H G E T L GQ +++ G P + LP QP P Sbjct: 519 MTT-------VEHPGHPEVTTATGLLGQPEATMVLELPGQPVATTALELPGQPSVTGVPE 571 Query: 518 RPCSPS 523 P PS Sbjct: 572 LPGLPS 577 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 43.5 bits (101), Expect = 5e-04 Identities = 70/249 (28%), Positives = 86/249 (34%), Gaps = 47/249 (18%) Query: 309 PREPAGAPQRHSLSEITYLGQPDISI---------LQPSNVPPPQILSPLSYAPNAAPEV 359 P PA P + + S LG P + L P PPPQ L+ P AP Sbjct: 355 PSPPATPPSQATTS----LGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPS 410 Query: 360 GP--PSYAPQVTPEAQFPFYAPQAISKVQPSSYAPQATPDSWPPSYGVCMEGSGKDSPTG 417 P P +P TP Q P A+ +Q AP + P S P S SP+ Sbjct: 411 PPASPPLSPLATPSPQAP--NALAVHLLQ----APFSPPPSPPVQAPFSPPASPPVSPSA 464 Query: 418 TLSS---PKHLRPKGQLQKEPPAGSCMLGGLS--LQEVTSLAMEESQEAKSLHQ-PLGIC 471 T S P P Q+ PPA M + Q LA Q AK Q P + Sbjct: 465 TPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALA 524 Query: 472 TDRTSDPNVLHSGEEGTPQYLKGQLPLLSSVQIEGHPMSLP------------LQ-PPSR 518 T P GQ P S + P++ P LQ PPS Sbjct: 525 TPPL-------QALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP 577 Query: 519 PCSPSDQGP 527 P SP+ Q P Sbjct: 578 PASPTLQAP 586 Score = 40.4 bits (93), Expect = 0.004 Identities = 47/163 (28%), Positives = 60/163 (36%), Gaps = 25/163 (15%) Query: 257 PPAPPNSLNVQRVLTFQPLRFIQEHVLIPVFDLSGPSSLAQPVQYSQIRVSGPREPAGAP 316 PP+PP S + + T P Q + V L P S P Q S P P +P Sbjct: 408 PPSPPASPPLSPLATPSP----QAPNALAVHLLQAPFS-PPPSPPVQAPFSPPASPPVSP 462 Query: 317 QRHSLSEIT-YLGQPDISI---------LQPSNVPPPQILSPLSYAP--------NAAPE 358 S+ L P + + + PS PPPQ PL+ P A P Sbjct: 463 SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPA 522 Query: 359 VGPPSYAPQVTPEAQFPFYAPQAISKVQPSSYAPQATPDSWPP 401 + P +P A FP AP + S P S P ATP P Sbjct: 523 LATPPLQALPSPPASFPGQAPFSPSASLPMS--PLATPPPQAP 563 Score = 31.6 bits (70), Expect = 2.1 Identities = 70/271 (25%), Positives = 92/271 (33%), Gaps = 59/271 (21%) Query: 290 SGPSSLAQPVQYSQIRVSGPREPAGAPQRHSLSEITYLGQPDISILQPSNVPPPQILSPL 349 S + L+ P + PR PA Q + L+P V PP+ Sbjct: 244 SSATPLSSPARSGPSARGTPRAPAHPSQPKPKG---------LQALRPPQVTPPR----- 289 Query: 350 SYAPNAAPEVGPPSYAPQVTPEAQFPFYAPQAISKVQPSSYAPQATPDSWPPSYGVCMEG 409 +AAP +GP S +P TP +P A + Q P ATP S Sbjct: 290 ---KDAAPALGPLSSSPLATP-------SPSAALQSQAPPTLP-ATPHS----------- 327 Query: 410 SGKDSPTGTLSSPKHLRPKGQLQKEPPAGSCMLGGLSLQEVTS-LAMEESQEAKSLHQPL 468 S T L++P L P PP SLQ + S A SQ SL P Sbjct: 328 ---SSLTCQLATPLPLAPPS--PSAPP---------SLQTLPSPPATPPSQATTSLGSPT 373 Query: 469 GICTDRTSDPNVLHSGEEGTPQYLKGQLPLLSSVQIEGHPMSLPLQPPSRP-CSPSDQGP 527 T L PQ P L+ ++ P S P PP P +PS Q P Sbjct: 374 LQATHSFLPSPPLSPLATPPPQ----APPALALPPLQA-PPSPPASPPLSPLATPSPQAP 428 Query: 528 SPWG--LLESLVCPKDEAKSPAPETSDLEQP 556 + LL++ P AP + P Sbjct: 429 NALAVHLLQAPFSPPPSPPVQAPFSPPASPP 459 Score = 30.4 bits (67), Expect = 4.6 Identities = 29/106 (27%), Positives = 39/106 (36%), Gaps = 14/106 (13%) Query: 306 VSGPREPA----GAPQRHSLSEITYLGQPDISILQPSNVPPPQILSPLSYAPNAAPEVGP 361 VSGPR G P S S + L PD++ S P+ L P P Sbjct: 598 VSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASP 657 Query: 362 PSYAPQVTPEAQFPFYAPQAISKVQPSSYAPQATPDS---WPPSYG 404 P P+A+ P A S+ A + P + WPP+ G Sbjct: 658 P-------PDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATG 696 >gi|122937496 WAS/WASL interacting protein family, member 3 [Homo sapiens] Length = 483 Score = 42.4 bits (98), Expect = 0.001 Identities = 69/273 (25%), Positives = 94/273 (34%), Gaps = 55/273 (20%) Query: 291 GPSSLAQPVQYSQIRVSGPREPAGAPQRHSLSEI-----TYLGQPDISILQPSNVPPPQ- 344 GP S A + +SGP P +P+ + SE T +P++ P PPP Sbjct: 125 GPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPP 184 Query: 345 -ILSPL-SYAPNAAPEVGPPSYAPQVTPEAQFPFYAPQAISKVQPSSYAPQATPDSWPPS 402 + PL S +P P V PP + P AP P P TP PP+ Sbjct: 185 PLPPPLPSSSPIKTPLVSPPG----PLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPA 240 Query: 403 YGVCMEGSGKDSPTGTLSSPKHLRP-KGQLQKEPPAGSCMLGGLSLQEVTSLAMEESQEA 461 + D +P HL P L PP C GL + + +++QE Sbjct: 241 SVL------SDKAVKPQLAPLHLPPIPPPLPLLPP---CGYPGLKAEPAS--PAQDAQEP 289 Query: 462 KSLHQPL---GICTDRTSDPNVLHSGEEGTPQYLKGQLPLLSSVQIEGHPMSLPLQPPSR 518 + PL C+ R S L + + G S PP Sbjct: 290 PAPPPPLPPYASCSPRAS----------------------LPAPPLPGVNSSSETPPPLP 327 Query: 519 PCSPSDQGPSPWGLLESLVCPKDEAKSPAPETS 551 P SPS Q P ++L P PAP S Sbjct: 328 PKSPSFQAPPQKAGAQALPAP------PAPPGS 354 >gi|110832843 TBP-associated factor 4 [Homo sapiens] Length = 1085 Score = 42.0 bits (97), Expect = 0.002 Identities = 46/194 (23%), Positives = 71/194 (36%), Gaps = 20/194 (10%) Query: 337 PSNVPPPQILSPLSYAPNAAPEVGPPSYAPQVTPEAQFPFYAPQAISKVQPSSYAPQATP 396 P+ PPP +P + A GPP+ AP V P P A + AP P Sbjct: 266 PAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPP--------PAAAQNGGSAGAAPAPAP 317 Query: 397 DSWPPSYGVCMEGSGKDSPTGTLSSP----KHLRPKGQLQKEPPAGSCMLGGLSLQEVTS 452 + P+ GV SG+ P ++P K PK +Q PPA + S Sbjct: 318 AAGGPA-GV----SGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAAS 372 Query: 453 LAMEESQEAKSLHQPLGICTDRTSDPNVLHSGEEGTPQYLKGQLP--LLSSVQIEGHPMS 510 + + + + +L P + P L G G + P S ++ P Sbjct: 373 MVIGPTMQG-ALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTV 431 Query: 511 LPLQPPSRPCSPSD 524 L + P P +P++ Sbjct: 432 LAPRLPQPPQNPTN 445 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 42.0 bits (97), Expect = 0.002 Identities = 58/245 (23%), Positives = 87/245 (35%), Gaps = 30/245 (12%) Query: 309 PREPAGAPQ--RHSLSEITYLGQPDISILQPSNVPPPQILSPLSYAPNAAPEVGPPSYAP 366 P PA P + L+ + G P+ +++ P + SP AP P PPS P Sbjct: 1264 PTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTP-PAATPPS--P 1320 Query: 367 QVTPEAQFPFYAPQAISKVQPSSYAPQATPDSWPPSYGVCMEGSGKDSPTGTLSSPKHLR 426 + +P P AP + PS P + P S G S K+ PT ++P H Sbjct: 1321 KGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKG 1380 Query: 427 PKGQLQKEPPAGSCMLGGLSLQEVTSLAMEESQEAKSLHQPLGICTDRTSDPNVLHSGEE 486 P G + + TS A+ K+ P+ E Sbjct: 1381 GPAMTPPSPKRGPAIPSPKG--DPTSPAVIPLSPKKAPATPV---------------TRE 1423 Query: 487 GTPQYLKGQL--PLLSSVQIEGHPMSLPLQPPSRPCSPSDQGPSPWGLLESLVCPKDEAK 544 G KG L P ++ V ++ P + P P +PS +G V P + Sbjct: 1424 GAATPSKGDLTPPAVTPVSLKKAPAT--SAPKGGPATPSSKGDPTL----PAVTPPSPKE 1477 Query: 545 SPAPE 549 PAP+ Sbjct: 1478 PPAPK 1482 Score = 39.7 bits (91), Expect = 0.008 Identities = 57/236 (24%), Positives = 80/236 (33%), Gaps = 32/236 (13%) Query: 312 PAGAPQRHSLSEITYLGQPDISILQPSNVPPPQILSPLSYAPNAAPEVGPPSYAPQVTPE 371 P GAP + + + G ++ P P +P S P P PP AP TP Sbjct: 1214 PKGAPTTPAATPPSPKG--GLATPSPKGAPTTPAATPPS--PKGGPATPPPKGAP--TPP 1267 Query: 372 AQFPFYAPQAISKVQPSSYAPQATPDSWPPSYGVCMEGSGKDSPTGTLSSPKHLRPKGQL 431 A P ++ P AP + P G K +PT ++P PKG Sbjct: 1268 AATPPSLKGGLA-TPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPS--PKGSP 1324 Query: 432 QKEPPAGSCMLGGLSLQEVTSLAMEESQEAKSLHQPLGICTDRTSDPNVLHSGEEGTPQY 491 PP G+ + A + P G T + P+ G TP Sbjct: 1325 GTPPPKGA-----------------PTPPAVTPPSPKGTPTLPATTPS--SKGGPTTPSS 1365 Query: 492 LKGQLPLLSSVQIEGHPMSLPLQPPSRPCSPSDQGPSPWGLLESLVCPKDEAKSPA 547 +G P ++ +G P P P P PS +G V P K+PA Sbjct: 1366 KEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDP----TSPAVIPLSPKKAPA 1417 Score = 38.5 bits (88), Expect = 0.017 Identities = 58/241 (24%), Positives = 84/241 (34%), Gaps = 47/241 (19%) Query: 309 PREPAGAPQRHSLSEITYLGQPDISILQPSNVPPPQILS-------PLSYAPNAAPEVGP 361 P P GAP +++ ++ P L P P P +++ P + AP AP + Sbjct: 858 PPSPKGAPTPSAVTPLS----PKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSM 913 Query: 362 PSY---------APQVTPEAQFPFYAPQAISKVQPSSYAPQATPDSWPPSYGVCMEGSGK 412 S AP+ P + P AP + PS ATP P + + Sbjct: 914 TSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPS---PKWAPTPPAATP 970 Query: 413 DSPTGTLSSPKHLRPKGQLQKEPPAGSCMLGGLSLQEVTSLAMEESQEAKSLHQPLGICT 472 SP G ++P PKG PPA + + + P G T Sbjct: 971 PSPKGGPATPS---PKG--APTPPAAT---------------PPSPKGGPATPSPKGAPT 1010 Query: 473 DRTSDPNVLHSGEEGTPQYLKGQL--PLLSSVQIEGHPMSLPLQPPSRPCSPSDQGPSPW 530 P TP + KG P + +G P + PL P P +P+ PSP Sbjct: 1011 PPAVTPPSPKGSPAATP-FPKGASTPPAATPPSPKGSPAATPL-PKGAPTTPAATLPSPK 1068 Query: 531 G 531 G Sbjct: 1069 G 1069 Score = 35.8 bits (81), Expect = 0.11 Identities = 84/308 (27%), Positives = 107/308 (34%), Gaps = 88/308 (28%) Query: 289 LSGPSSLAQPVQYSQIRVSGPREP---AGAPQRHSLS---EITYLGQPDISILQPSNVPP 342 LS ++L QP GP P + APQ+ LS + + P P VP Sbjct: 32 LSVTAALGQP---------GPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPF 82 Query: 343 PQILS----PLSYAPNAAPEVGPPSYAPQVTPEA---QFPFYAPQAISKVQPSSYAPQA- 394 PQ S PL AP A P P P ++P A P AP K PSS AP A Sbjct: 83 PQSSSGTALPLGTAPEA-PTFLPNLIGPPISPAALALASPMIAPTL--KGTPSSSAPLAL 139 Query: 395 ---TPDSW-------------PPSYGVCMEGSGKDSPTGTLSSP-KHLRPKGQLQKEP-- 435 P S PPS V GS TLS+P PK L K P Sbjct: 140 VALAPHSVQKSSAFPPNLLTSPPSVAVAESGS-----VITLSAPIAPSEPKTNLNKVPSE 194 Query: 436 --------PAGSCMLGGLSLQEVTSLAMEESQEAKSLHQPLGICTDRTSDPNVLHSGEEG 487 P+ C++ + VT +A + SG Sbjct: 195 VVPNPKGTPSPPCIVSTVPYHCVTPMAS-------------------------IQSGVAS 229 Query: 488 TPQYLKGQLPLLSSVQIEGHPMSLPLQPPSRPCSPSDQGP-SPWGLL----ESLVCPKDE 542 PQ ++S Q++ +S L P P S S +GP SP L +SL Sbjct: 230 LPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSS 289 Query: 543 AKSPAPET 550 K+ P T Sbjct: 290 QKTAGPNT 297 Score = 33.9 bits (76), Expect = 0.42 Identities = 78/307 (25%), Positives = 109/307 (35%), Gaps = 82/307 (26%) Query: 292 PSSLAQPVQYSQIRVSGPR-EPAGAPQRHSLSEITYLGQPDISILQPSNVPPPQILSPLS 350 P + V ++ + P+ E A P +LS LGQP ++ P + P Q PLS Sbjct: 2 PGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQ--CPLS 59 Query: 351 YAPNAAP-------------------------EVGPPSYAPQVTPEAQFPFYAPQAIS-- 383 A A+P +G AP P P +P A++ Sbjct: 60 AANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALA 119 Query: 384 --------KVQPSSYAPQA----TPDS-------------WPPSYGVCMEGSGKDSPTGT 418 K PSS AP A P S PPS V GS T Sbjct: 120 SPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGS-----VIT 174 Query: 419 LSSP-KHLRPKGQLQKEP----------PAGSCMLGGLSLQEVTSLAMEESQEAKSLHQ- 466 LS+P PK L K P P+ C++ + VT +A +S A SL Q Sbjct: 175 LSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVA-SLPQT 233 Query: 467 ----PLGICTDRTSD---PNVLHSGEEGTPQYLKGQL--PLLSSVQIEGHPMSLPLQPPS 517 L I + + D +VL S + LKG + P S+ + P+ Q + Sbjct: 234 TPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTA 293 Query: 518 RPCSPSD 524 P +P D Sbjct: 294 GPNTPPD 300 Score = 33.1 bits (74), Expect = 0.71 Identities = 68/292 (23%), Positives = 101/292 (34%), Gaps = 35/292 (11%) Query: 292 PSSLAQPVQYSQIRVSGPREPAGAPQRHSLSEITYLGQPDISILQPSNVPPPQIL-SPLS 350 PS P + I +S + PA R + P L P V P + +P + Sbjct: 1396 PSPKGDPTSPAVIPLSPKKAPATPVTREGAAT------PSKGDLTPPAVTPVSLKKAPAT 1449 Query: 351 YAPNAAPEV----GPPSYAPQVTPEAQFPFYAPQAISKVQPSSYAPQATPDSWPPSYGVC 406 AP P G P+ P VTP + AP+ ++ AP P+ Sbjct: 1450 SAPKGGPATPSSKGDPTL-PAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAV 1508 Query: 407 MEGSGKDSPTGTLSSPKHLRPKGQ-LQKEPPAGSCMLGGLSLQEVT------SLAMEESQ 459 + S K+ P S + P L K+ PA L +T + A+ + Sbjct: 1509 IPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPK 1568 Query: 460 EAKSLHQPLGICTDRTSDPNVLHSGEEGTPQYLKGQLPLLSSVQIEGHPMSLPLQPPSRP 519 EA + + +S P V S +G P + +P P P P P Sbjct: 1569 EAPATPS----SKEASSPPAVTPSTYKGAPSPKELLIP---PAVTSPSPKEAPTPPAVTP 1621 Query: 520 CSPSDQGPSPWGLLESLVCPKDEAKSPAPETSDL-EQPTELDSLFRGLALTV 570 SP ++GP + PK SP S L + PT S+ + TV Sbjct: 1622 PSP-EKGP-------ATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATV 1665 Score = 32.3 bits (72), Expect = 1.2 Identities = 71/288 (24%), Positives = 106/288 (36%), Gaps = 52/288 (18%) Query: 292 PSSLAQPVQYSQIRVSGPREPAGAPQRHSLSEITYLGQPDISILQPSNVPPPQILSPLSY 351 P+ P S S P + + + S L P ++ P P P ++P S Sbjct: 1565 PTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPS- 1623 Query: 352 APNAAPEVGPPSYAPQVTPEAQFPFYAPQAI--SKVQPSSYA-------PQATPDSWPPS 402 PE GP + AP+ TP + P P ++ S P+S PQA+ P Sbjct: 1624 -----PEKGPATPAPKGTPTS--PPVTPSSLKDSPTSPASVTCKMGATVPQASK-GLPAK 1675 Query: 403 YG------VCMEGSGKDSPTGTLSSPKHLRPKGQLQKEPP------AGSCMLGGLS---- 446 G V + + + +P T + K + K PP A + G LS Sbjct: 1676 KGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAP 1735 Query: 447 -----LQEVTSLAMEESQEAKSLHQPLGICTDRTSDPNVLHSGEEGTPQYLKGQLPLLSS 501 +Q+ +S + + S PL + S P + E+ P+ P +S Sbjct: 1736 APLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPK------PESAS 1789 Query: 502 VQIE-GHPMSLPLQPPSRPCSPSDQ---GPSPWGLLES---LVCPKDE 542 V P+SLPL P P P Q SP +LES + P DE Sbjct: 1790 VSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADE 1837 Score = 31.6 bits (70), Expect = 2.1 Identities = 65/263 (24%), Positives = 91/263 (34%), Gaps = 48/263 (18%) Query: 292 PSSLAQPVQYSQIRVSGPREPAGAPQRHSLSE------ITYLGQPDISILQPSNVPPPQI 345 P ++ P + P+E P S TY G P L + PP + Sbjct: 1550 PPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKEL----LIPPAV 1605 Query: 346 LSPLSYAPNAAPEVGPPSYAPQVTPEAQFPFYAPQAISKVQPSSYAPQATPDSWPPSYGV 405 SP P V PPS PE P++ AP+ TP S P + Sbjct: 1606 TSPSPKEAPTPPAVTPPS------PEKG-------------PATPAPKGTPTSPPVT--- 1643 Query: 406 CMEGSGKDSPTGTLS-SPKHLRPKGQLQKEPPAGSCMLGGLSLQEVTSLAMEESQEAKSL 464 S KDSPT S + K Q K PA G +L+EV ES + Sbjct: 1644 --PSSLKDSPTSPASVTCKMGATVPQASKGLPAKK---GPTALKEVLVAPAPESTPIITA 1698 Query: 465 HQPLGICTDRTSDPNVLHSGEEGTPQYLKGQLPLLSSVQIEGHPMSLPLQ-PPSRPCSPS 523 G T ++S + + KG L ++ + LP+Q S+ Sbjct: 1699 PTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPL------LPVQKDSSKTAKGK 1752 Query: 524 DQGPSPWGLLESLVCPKDEAKSP 546 D SP G L P+ +A +P Sbjct: 1753 DASHSPKG---PLAPPESKASTP 1772 >gi|15721939 metastatic lymph node 51 [Homo sapiens] Length = 703 Score = 41.6 bits (96), Expect = 0.002 Identities = 52/185 (28%), Positives = 69/185 (37%), Gaps = 36/185 (19%) Query: 252 RYVTKPPAPPNSLNVQRVLTFQPLRF---IQEHVLIPVFDLSGPSSLAQP-VQYSQIRVS 307 R V +PPAPP +++ + PL+F I H P L L QP + + Sbjct: 528 RPVPEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPA-PLPPQGMLVQPGMNLPHPGLH 586 Query: 308 GPREPAGAPQRHSLSEITYLGQPDISILQPSNVPPPQILSP---------------LSYA 352 + PA P L P +S + P PP Q+L+P YA Sbjct: 587 PHQTPAPLPNPG-------LYPPPVS-MSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYA 638 Query: 353 PNAAPEVGPPSYAPQVTPEAQ----FPFYAPQAISKVQPSSYAPQATPDS---WPPSYGV 405 P A P PP P +Q +Y P A +VQP P+ TP PP V Sbjct: 639 PGALPPPPPPHLYPNTQAPSQVYGGVTYYNP-AQQQVQPKPSPPRRTPQPVTIKPPPPEV 697 Query: 406 CMEGS 410 GS Sbjct: 698 VSRGS 702 >gi|222136575 interleukin 10 receptor, alpha precursor [Homo sapiens] Length = 578 Score = 41.2 bits (95), Expect = 0.003 Identities = 38/119 (31%), Positives = 52/119 (43%), Gaps = 7/119 (5%) Query: 5 LTILTVGSLAAHAPEDPSDLLQHVKFQSSNFENILTWDSGPEGTPDTVYSIEYKTYGERD 64 L L +GS AH E PS V F++ F +IL W P + T Y + YG Sbjct: 12 LLSLRLGS-DAHGTELPSP--PSVWFEAEFFHHILHWTPIPNQSESTCYEVALLRYGIES 68 Query: 65 WVAKKGCQRITRKSCNLTVETGNL--TELYYARVTAVSAGGRSATKMTDRFSSLQHTTL 121 W + C + S +LT T +L + Y ARV AV S +T+ S+ TL Sbjct: 69 WNSISNCSQTL--SYDLTAVTLDLYHSNGYRARVRAVDGSRHSNWTVTNTRFSVDEVTL 125 >gi|47419934 interferon gamma receptor 2 precursor [Homo sapiens] Length = 337 Score = 41.2 bits (95), Expect = 0.003 Identities = 29/91 (31%), Positives = 43/91 (47%), Gaps = 12/91 (13%) Query: 3 TLLTILTVGSLAAHAPEDPSDLL---QHVKFQSSNFENILTWD--SGPEGTPDTVYSIEY 57 +LL +L V + AA AP DP L QH K + N E +L+W+ + T VY +++ Sbjct: 8 SLLLLLGVFAAAAAAPPDPLSQLPAPQHPKIRLYNAEQVLSWEPVALSNSTRPVVYQVQF 67 Query: 58 KTYGERDWVAKK------GCQRITRKSCNLT 82 K Y + W C +IT C+ T Sbjct: 68 K-YTDSKWFTADIMSIGVNCTQITATECDFT 97 >gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] Length = 2217 Score = 41.2 bits (95), Expect = 0.003 Identities = 55/219 (25%), Positives = 83/219 (37%), Gaps = 34/219 (15%) Query: 336 QPSNVPPPQILSPLSYAPNAAPEVGPPSYAPQVTPEAQFPFYAPQAISKVQPSSYAPQAT 395 QPS + Q+LS P+ P P AP P P A AT Sbjct: 1358 QPSFLASQQLLSQAG--PSNPPGAPPAPLAPSSPPVTALP------------QDGAAPAT 1403 Query: 396 PDSWPPSYGVCMEGSGKDSPTGTLSSPKHLRPKGQLQKEPPAGSCMLGGLSLQEVTSLAM 455 P+ G + G +P G S + +P + + P A ++ GL+ A Sbjct: 1404 STMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEA- 1462 Query: 456 EESQEAKSLHQPLGICTDRTSDPNVLHSGEEGTPQYLKGQ-LPL---------LSSVQIE 505 +++A + +PL P S GTPQ GQ PL L++ Q+ Sbjct: 1463 ASTRDASAPREPL-------PPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLP 1515 Query: 506 GHPM--SLPLQPPSRPCSPSDQGPSPWGLLESLVCPKDE 542 P+ ++P QPPS S + P G ++S + DE Sbjct: 1516 SPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDE 1554 Score = 32.7 bits (73), Expect = 0.93 Identities = 38/139 (27%), Positives = 54/139 (38%), Gaps = 11/139 (7%) Query: 254 VTKPPAPPNSLNVQRVLTFQPLRFIQEHVLIPVFDLSGPSSLAQPVQYSQIRVSGPRE-P 312 + +P P L Q V+ QP+ L P + P+ L +P+Q Q + + P Sbjct: 734 LAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQL-KPLQMPQAPLQPLAQVP 792 Query: 313 AGAPQRHSLSEITYLGQ--------PDISILQPSNVPPPQILSPLSYAPNAAPEVGPPSY 364 P + IT L PD+ VPPPQ SP P+ A + P S Sbjct: 793 PQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASP 852 Query: 365 A-PQVTPEAQFPFYAPQAI 382 A P + P AP A+ Sbjct: 853 ALPLQAVKLPHPPGAPLAM 871 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 40.8 bits (94), Expect = 0.003 Identities = 76/292 (26%), Positives = 101/292 (34%), Gaps = 65/292 (22%) Query: 292 PSSLAQPVQYSQIRVSGPREPAGAPQRHSLSEITYLGQPDISILQ--PSNVPPPQILSPL 349 PS L P + ++ P P AP + + L P +S L P PP L PL Sbjct: 573 PSPLTTPPPETPSSIATP--PPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPL 630 Query: 350 SYAPN--AAPEVGP---PS---------------YAPQVTPEAQFPFYAPQAISKVQPSS 389 P+ A+P + P PS ++P +P Q PF +P A V PS+ Sbjct: 631 QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF-SPPASPPVSPSA 689 Query: 390 YAPQATPDSW-------PPSYGVCMEGSGKDSPTGT---LSSPKHLRPKGQLQKEPPAGS 439 P P S PPS S SP+ T + P P Q+ PPA Sbjct: 690 TPPSQAPPSLAAPPLQVPPS----PPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASP 745 Query: 440 CMLGGLS-------LQEVTSLAMEESQEAKSLHQPLGICTDRTSDPNVLHSGE----EGT 488 M + L L + S A PL + P L + Sbjct: 746 PMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQA--PPALATPPLQALPSP 803 Query: 489 PQYLKGQLPLLSSVQIEGHPMSLP------------LQ-PPSRPCSPSDQGP 527 P GQ P S + P++ P LQ PPS P SP+ Q P Sbjct: 804 PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP 855 Score = 38.5 bits (88), Expect = 0.017 Identities = 61/256 (23%), Positives = 83/256 (32%), Gaps = 38/256 (14%) Query: 307 SGPREPAGAPQRHSLSEITYLGQPDISILQPSNVPPPQILSPLSYAPNAAPEVGPPSYAP 366 SG + P ++ + + P + P + PP +P S +P PPS AP Sbjct: 310 SGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAP 369 Query: 367 --QVTPEAQFPFYAPQAISKVQPSSYAPQATPDSWPPSYGVCMEGSGKDSPTGTLSSPKH 424 TP P AP ++ + P P S L+SP Sbjct: 370 PSMTTP----PMQAPPSLQTIPPIQ-----VPHS--------------------LTSPSL 400 Query: 425 LRPKGQLQKEPPAGSCMLGGLSLQEVTS-LAMEESQEAKSLHQPLGICTDRTSDPNVLHS 483 P L + LG +LQ S L M Q SL P + P + Sbjct: 401 QAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPL--- 457 Query: 484 GEEGTPQYLKGQLPLLSSVQIEGHPMSLPLQPPSRPCSPSDQGPSPWGLLESLVCPKDEA 543 P L PL +S+ P+S PL S SP L SL+ P E Sbjct: 458 ---QAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLET 514 Query: 544 KSPAPETSDLEQPTEL 559 +S S P L Sbjct: 515 QSSLAPPSLQTPPASL 530 Score = 35.4 bits (80), Expect = 0.14 Identities = 74/309 (23%), Positives = 105/309 (33%), Gaps = 35/309 (11%) Query: 260 PPNSLNVQRVLTFQPLRFIQEHVLIPVFDLSGPSSLAQPVQYSQIRVSGPREPAGAPQRH 319 PP+S +Q L+ +Q + V LS P ++ S + P+ P + Sbjct: 451 PPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMP 510 Query: 320 SLSEITYLGQPDISILQPSNVPPPQILSPLSYAPNAAPEVGPPSYAPQVTPE-------A 372 L + L P + P+++ P PL P+ AP + AP TP A Sbjct: 511 PLETQSSLAPPSLQ-TPPASLTTP----PLENLPSLAPPPLQTASAPLTTPHLETPPCPA 565 Query: 373 QFPFYAPQAISKV----QPSSYA---PQATPD-SWPPSYGVCMEGSGKDSPTGTLSSPKH 424 P AP + PSS A PQA P + PP G+ + + P Sbjct: 566 PCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXL 625 Query: 425 LRPKGQLQKEPPAGSCM--LGGLSLQEVTSLAMEESQEAKSLHQPLGICTDRTSDPNVLH 482 P Q PPA + L S Q +LA+ Q A P S P Sbjct: 626 ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ-APFSPPPSPPVQAPFSPPASPP 684 Query: 483 SGEEGTPQYLKGQLPLLSSVQIEGHPMSLPLQPPSRP-----CSPSDQGPSPWGLLESLV 537 TP P + + P+ +P PP+ P +P Q P P V Sbjct: 685 VSPSATP-------PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQV 737 Query: 538 CPKDEAKSP 546 P A P Sbjct: 738 PPSPPASPP 746 Score = 30.4 bits (67), Expect = 4.6 Identities = 29/106 (27%), Positives = 39/106 (36%), Gaps = 14/106 (13%) Query: 306 VSGPREPA----GAPQRHSLSEITYLGQPDISILQPSNVPPPQILSPLSYAPNAAPEVGP 361 VSGPR G P S S + L PD++ S P+ L P P Sbjct: 867 VSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASP 926 Query: 362 PSYAPQVTPEAQFPFYAPQAISKVQPSSYAPQATPDS---WPPSYG 404 P P+A+ P A S+ A + P + WPP+ G Sbjct: 927 P-------PDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATG 965 >gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo sapiens] Length = 1235 Score = 40.8 bits (94), Expect = 0.003 Identities = 51/197 (25%), Positives = 71/197 (36%), Gaps = 24/197 (12%) Query: 357 PEVGPPSYAPQVTPEAQFPFYAPQAISKVQPSSYAPQATPDSWPPSYGVCMEGSGKDSPT 416 P+V P PQ P+ + P P VQ + PQ P S P P Sbjct: 300 PQVAQPIPQPQTEPQLRAPSPDPDL---VQRTEAPPQPPPLSTQP-------------PQ 343 Query: 417 GTLSSPKHLRPKGQLQKEP-PAGSCMLGGLSLQEVTSLAMEESQEAKSLHQPLGICTDRT 475 G + P+ Q+Q+ P P L +L V + A+SL QPL + Sbjct: 344 GPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPV-----QAHPSAQSLSQPLSAYNSSS 398 Query: 476 SDPNVLHSGEEGTPQYLKGQLPLLS-SVQIEGHPMSLPLQPPSRPCSPSDQGPSPWGLLE 534 N L S TP + P +S P+SLP P +P+ Q P+ Sbjct: 399 LSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPA-HSHHP 457 Query: 535 SLVCPKDEAKSPAPETS 551 ++ P P P TS Sbjct: 458 NMFAPPTALPPPPPLTS 474 >gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo sapiens] Length = 1259 Score = 40.8 bits (94), Expect = 0.003 Identities = 51/197 (25%), Positives = 71/197 (36%), Gaps = 24/197 (12%) Query: 357 PEVGPPSYAPQVTPEAQFPFYAPQAISKVQPSSYAPQATPDSWPPSYGVCMEGSGKDSPT 416 P+V P PQ P+ + P P VQ + PQ P S P P Sbjct: 300 PQVAQPIPQPQTEPQLRAPSPDPDL---VQRTEAPPQPPPLSTQP-------------PQ 343 Query: 417 GTLSSPKHLRPKGQLQKEP-PAGSCMLGGLSLQEVTSLAMEESQEAKSLHQPLGICTDRT 475 G + P+ Q+Q+ P P L +L V + A+SL QPL + Sbjct: 344 GPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPV-----QAHPSAQSLSQPLSAYNSSS 398 Query: 476 SDPNVLHSGEEGTPQYLKGQLPLLS-SVQIEGHPMSLPLQPPSRPCSPSDQGPSPWGLLE 534 N L S TP + P +S P+SLP P +P+ Q P+ Sbjct: 399 LSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPA-HSHHP 457 Query: 535 SLVCPKDEAKSPAPETS 551 ++ P P P TS Sbjct: 458 NMFAPPTALPPPPPLTS 474 >gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] Length = 638 Score = 40.8 bits (94), Expect = 0.003 Identities = 69/282 (24%), Positives = 102/282 (36%), Gaps = 52/282 (18%) Query: 290 SGPSSLAQPVQYSQIRVSGPREPAGAPQR--HSLSEITYLGQPDISILQPSNVPPPQILS 347 SGPS ++P Y + GP P G P H L +T G + N PPP + Sbjct: 371 SGPSE-SRP--YHGMHGGGPGGPGGGPHSFPHPLPSLTG-GHGGHPMQHNPNGPPPPWMQ 426 Query: 348 P----LSYAPNAAPEVGPPSYAPQV--TPEAQFPFYAPQAISKVQPSSYAPQATPDSWPP 401 P ++ P+ GPP + TP + Q + P P PP Sbjct: 427 PPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPP-PP 485 Query: 402 SYGVCMEGSGKDSPTGTLSSPKHLRPKGQLQKEPPAGSCMLGGLSLQEVTSLAMEESQEA 461 S G P+G L P + + Q PP S M T L +++ Sbjct: 486 S------GQPPPPPSGPL--PPWQQQQQQPPPPPPPSSSMASS------TPLPWQQNTT- 530 Query: 462 KSLHQPLGICTDRTSDPNVLHSGEEGTPQYLKGQLPLLSSV---QIEGHPMSLPL----Q 514 T TS +G P + + Q +S Q++G+P +PL Q Sbjct: 531 ----------TTTTS------AGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQ 574 Query: 515 PPSRPCSPSDQGPSPWGLLESLVCPKDEAKSPAPETSDLEQP 556 PP P +P P P G ++ P+ P+ E+ D +P Sbjct: 575 PPLPPGAPPPPPPPPPGSAGMMIPPRG-GDGPSHESEDFPRP 615 >gi|19924099 synapsin I isoform Ia [Homo sapiens] Length = 705 Score = 40.8 bits (94), Expect = 0.003 Identities = 48/177 (27%), Positives = 59/177 (33%), Gaps = 23/177 (12%) Query: 291 GPSSLAQPVQYSQIRVSGPREPAGAPQRHSLSEITYLGQPDISILQPSNVPPPQILSPLS 350 GP +P Q +SG PAG+P L T Q S P + P++ Sbjct: 478 GPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVA 537 Query: 351 YAPNAAPEVGPPSY--------APQVTPEAQFPFYAPQAISKVQPSSYAPQATPDSWPPS 402 P A P PP+ PQ T + AP S P Q P P Sbjct: 538 GGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGP 597 Query: 403 YGVCMEGS--GKDSPTG--TLSSPKHL------RPKGQL-----QKEPPAGSCMLGG 444 G + S G TG T P+ RPK QL Q PP + GG Sbjct: 598 AGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGG 654 >gi|19924097 synapsin I isoform Ib [Homo sapiens] Length = 669 Score = 40.8 bits (94), Expect = 0.003 Identities = 48/177 (27%), Positives = 59/177 (33%), Gaps = 23/177 (12%) Query: 291 GPSSLAQPVQYSQIRVSGPREPAGAPQRHSLSEITYLGQPDISILQPSNVPPPQILSPLS 350 GP +P Q +SG PAG+P L T Q S P + P++ Sbjct: 478 GPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVA 537 Query: 351 YAPNAAPEVGPPSY--------APQVTPEAQFPFYAPQAISKVQPSSYAPQATPDSWPPS 402 P A P PP+ PQ T + AP S P Q P P Sbjct: 538 GGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGP 597 Query: 403 YGVCMEGS--GKDSPTG--TLSSPKHL------RPKGQL-----QKEPPAGSCMLGG 444 G + S G TG T P+ RPK QL Q PP + GG Sbjct: 598 AGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGG 654 >gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens] Length = 1499 Score = 40.4 bits (93), Expect = 0.004 Identities = 59/207 (28%), Positives = 76/207 (36%), Gaps = 26/207 (12%) Query: 330 PDISILQPSNVPPPQILSPLSYAPNAAPEVGPPSYAPQVTPEAQFPFYAPQAISKVQPSS 389 P + Q VPP PLS P+ PP P P P AP A+ P Sbjct: 272 PRAKLDQAPKVPPTPEPLPLSTPSAGTPQSQPPPLPP---PPPPAPGSAPPAL---PPEG 325 Query: 390 YAPQATPDSWPPSYGVCMEGSG-----KDSPTGTLSSPKHLRPKGQLQKEPPAGSCMLGG 444 ++ D P S G G G ++PT T ++ L P G P G +LG Sbjct: 326 PPEDSSQDLAPNSVGAASTGGGTGGTHPNTPTATTAN-NPLPPGGDPSSAP--GPALLGE 382 Query: 445 LSL--QEVTSLAMEESQEAKSL-HQPLGICTDRTSDPNVLHSGEEGTPQYLKGQLPLLSS 501 + SL E + L H+ + T R + +L SGE T +LKG Sbjct: 383 AAAPGNGQRSLVGSEGLSKEQLEHRERSLQTLRDIERLLLRSGE--TEPFLKGP----PG 436 Query: 502 VQIEGHPMSLPLQPPSRPCSPSDQGPS 528 EG P P Q P P P PS Sbjct: 437 GAGEGGP---PAQAPPPPQQPPTAPPS 460 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.133 0.407 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 27,366,694 Number of Sequences: 37866 Number of extensions: 1550262 Number of successful extensions: 7437 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 34 Number of HSP's successfully gapped in prelim test: 403 Number of HSP's that attempted gapping in prelim test: 6341 Number of HSP's gapped (non-prelim): 1318 length of query: 574 length of database: 18,247,518 effective HSP length: 108 effective length of query: 466 effective length of database: 14,157,990 effective search space: 6597623340 effective search space used: 6597623340 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.