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Search of human proteins with 122937321
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|122937321 UNC homeobox [Homo sapiens]
(531 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|122937321 UNC homeobox [Homo sapiens] 1105 0.0
gi|12707580 paired-like homeobox 2b [Homo sapiens] 118 2e-26
gi|126116581 retina and anterior neural fold homeobox [Homo sapi... 106 5e-23
gi|24497589 aristaless related homeobox [Homo sapiens] 104 2e-22
gi|55743092 aristaless-like homeobox 4 [Homo sapiens] 103 5e-22
gi|113204604 aristaless-like homeobox 3 [Homo sapiens] 100 3e-21
gi|154813201 cartilage paired-class homeoprotein 1 [Homo sapiens] 100 4e-21
gi|34365783 visual system homeobox 2 [Homo sapiens] 99 1e-20
gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens] 99 1e-20
gi|14149760 orthopedia homeobox [Homo sapiens] 99 1e-20
gi|14249388 retina and anterior neural fold homeobox 2 [Homo sap... 99 1e-20
gi|46249382 paired-like homeobox 2a [Homo sapiens] 98 2e-20
gi|11056038 visual system homeobox 1 isoform a [Homo sapiens] 95 1e-19
gi|163965366 nascent polypeptide-associated complex alpha subuni... 95 1e-19
gi|22218349 diencephalon/mesencephalon homeobox 1 isoform b [Hom... 94 2e-19
gi|27436936 diencephalon/mesencephalon homeobox 1 isoform a [Hom... 94 2e-19
gi|4826912 paired-like homeodomain 3 [Homo sapiens] 94 4e-19
gi|110832843 TBP-associated factor 4 [Homo sapiens] 93 5e-19
gi|89145413 short stature homeobox 2 isoform a [Homo sapiens] 93 7e-19
gi|122937484 dorsal root ganglia homeobox [Homo sapiens] 92 9e-19
gi|87044888 short stature homeobox 2 isoform b [Homo sapiens] 92 1e-18
gi|6031203 short stature homeobox isoform SHOXb [Homo sapiens] 92 2e-18
gi|4506943 short stature homeobox isoform SHOXa [Homo sapiens] 92 2e-18
gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Ho... 90 6e-18
gi|4505619 paired box 7 isoform 1 [Homo sapiens] 89 1e-17
gi|7524359 paired box 7 isoform 2 [Homo sapiens] 89 1e-17
gi|207029223 paired box 7 isoform 3 [Homo sapiens] 89 1e-17
gi|188219638 paired box 3 isoform PAX3i [Homo sapiens] 88 2e-17
gi|31563348 paired box 3 isoform PAX3g [Homo sapiens] 88 2e-17
gi|31563346 paired box 3 isoform PAX3h [Homo sapiens] 88 2e-17
>gi|122937321 UNC homeobox [Homo sapiens]
Length = 531
Score = 1105 bits (2858), Expect = 0.0
Identities = 531/531 (100%), Positives = 531/531 (100%)
Query: 1 MMDGRLLEHPHAQFGGSLGGVVGFPYPLGHHHVYELAGHQLQSAAAAASVPFSIDGLLGG 60
MMDGRLLEHPHAQFGGSLGGVVGFPYPLGHHHVYELAGHQLQSAAAAASVPFSIDGLLGG
Sbjct: 1 MMDGRLLEHPHAQFGGSLGGVVGFPYPLGHHHVYELAGHQLQSAAAAASVPFSIDGLLGG 60
Query: 61 SCAAAASVVNPTPLLPAACGVGGDGQPFKLSDSGDPDKESPGCKRRRTRTNFTGWQLEEL 120
SCAAAASVVNPTPLLPAACGVGGDGQPFKLSDSGDPDKESPGCKRRRTRTNFTGWQLEEL
Sbjct: 61 SCAAAASVVNPTPLLPAACGVGGDGQPFKLSDSGDPDKESPGCKRRRTRTNFTGWQLEEL 120
Query: 121 EKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKKENTKKGPGRPAHNSHPT 180
EKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKKENTKKGPGRPAHNSHPT
Sbjct: 121 EKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKKENTKKGPGRPAHNSHPT 180
Query: 181 TCSGEPMDPEEIARKELEKMEKKKRKHEKKLLKSQGRHLHSPGGLSLHSAPSSDSDSGGG 240
TCSGEPMDPEEIARKELEKMEKKKRKHEKKLLKSQGRHLHSPGGLSLHSAPSSDSDSGGG
Sbjct: 181 TCSGEPMDPEEIARKELEKMEKKKRKHEKKLLKSQGRHLHSPGGLSLHSAPSSDSDSGGG 240
Query: 241 GLSPEPPEPPPPAAKGPGAHASGAAGTAPAPPGEPPAPGTCDPAFYPSQRSGAGPQPRPG 300
GLSPEPPEPPPPAAKGPGAHASGAAGTAPAPPGEPPAPGTCDPAFYPSQRSGAGPQPRPG
Sbjct: 241 GLSPEPPEPPPPAAKGPGAHASGAAGTAPAPPGEPPAPGTCDPAFYPSQRSGAGPQPRPG 300
Query: 301 RPADKDAASCGPGAAVAAVERGAAGLPKASPFSVESLLSDSPPRRKAASNAAAAAAAGLD 360
RPADKDAASCGPGAAVAAVERGAAGLPKASPFSVESLLSDSPPRRKAASNAAAAAAAGLD
Sbjct: 301 RPADKDAASCGPGAAVAAVERGAAGLPKASPFSVESLLSDSPPRRKAASNAAAAAAAGLD 360
Query: 361 FAPGLPCAPRTLIGKGHFLLYPITQPLGFLVPQAALKGGAGLEPAPKDAPPAPAVPPAPP 420
FAPGLPCAPRTLIGKGHFLLYPITQPLGFLVPQAALKGGAGLEPAPKDAPPAPAVPPAPP
Sbjct: 361 FAPGLPCAPRTLIGKGHFLLYPITQPLGFLVPQAALKGGAGLEPAPKDAPPAPAVPPAPP 420
Query: 421 AQASFGAFSGPGGAPDSAFARRSPDAVASPGAPAPAPAPFRDLASAAATEGGGGDCADAG 480
AQASFGAFSGPGGAPDSAFARRSPDAVASPGAPAPAPAPFRDLASAAATEGGGGDCADAG
Sbjct: 421 AQASFGAFSGPGGAPDSAFARRSPDAVASPGAPAPAPAPFRDLASAAATEGGGGDCADAG 480
Query: 481 TAGPAPPPPAPSPRPGPRPPSPAEEPATCGVPEPGAAAGPSPPEGEELDMD 531
TAGPAPPPPAPSPRPGPRPPSPAEEPATCGVPEPGAAAGPSPPEGEELDMD
Sbjct: 481 TAGPAPPPPAPSPRPGPRPPSPAEEPATCGVPEPGAAAGPSPPEGEELDMD 531
>gi|12707580 paired-like homeobox 2b [Homo sapiens]
Length = 314
Score = 118 bits (295), Expect = 2e-26
Identities = 93/266 (34%), Positives = 117/266 (43%), Gaps = 69/266 (25%)
Query: 74 LLPAACGVGG--DGQ-------PFKL-SDSGDPDKESPGCKRRRTRTNFTGWQLEELEKA 123
L P +C +G D Q P+KL +D G +++ K+RR RT FT QL+ELE+
Sbjct: 60 LTPGSCSLGTLRDHQSSPYAAVPYKLFTDHGGLNEKR---KQRRIRTTFTSAQLKELERV 116
Query: 124 FNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKKENTKKGPGRPAHNSHPTTCS 183
F E+HYPD++ RE LAL++DL E+RVQVWFQNRRAK+RK+E A N S
Sbjct: 117 FAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQERAAAAAAAAAKNG----SS 172
Query: 184 GEPMDPEEIARKELEKMEKKKRKHEKKLLKSQGRHLHSPGGLSLHSAPSSDSDSGGGGLS 243
G+ D R E K A S+D DS GG
Sbjct: 173 GKKSD--------------SSRDDESK------------------EAKSTDPDSTGG--- 197
Query: 244 PEPPEPPPPAAKGPGAHASGAAGTAPAPPGEPPAPGTCDPAFYPSQRSGAGPQPRPGRPA 303
P P P A+G G P+P G P A G GP PG+
Sbjct: 198 -----PGPNPNPTPSCGANGGGGGGPSPAGAPGAAGP------------GGPGGEPGKGG 240
Query: 304 DKDAASCGPGAAVAAVERGAAGLPKA 329
AA+ AA AA A GL A
Sbjct: 241 AAAAAAAAAAAAAAAAAAAAGGLAAA 266
Score = 37.7 bits (86), Expect = 0.026
Identities = 34/110 (30%), Positives = 38/110 (34%), Gaps = 7/110 (6%)
Query: 417 PAPPAQASFGAFSGPGGAPDSAFARRSPDAVASPGAPAPAPAPFRDLASAAATEGGGGDC 476
P P S GA G GG P A A A PG P P A+AAA
Sbjct: 200 PNPNPTPSCGANGGGGGGPSPAGA----PGAAGPGGPGGEPGKGGAAAAAAAAAAAAAAA 255
Query: 477 ADAGTAG-PAPPPPAPSPRPGPRPPSPAEEPATCGVPEPGAAAGPSPPEG 525
A A G A P PGP P + P + G P + P G
Sbjct: 256 AAAAAGGLAAAGGPGQGWAPGPGPITSI--PDSLGGPFASVLSSLQRPNG 303
Score = 37.0 bits (84), Expect = 0.045
Identities = 34/106 (32%), Positives = 37/106 (34%), Gaps = 21/106 (19%)
Query: 392 PQAALKGGAGLEPAPKDAPPAPAVPPAPPAQASFGAFSGPGGAPDSAFARRSPDAVASPG 451
P GG G P+P AP A A P GPGG P A + A A+
Sbjct: 206 PSCGANGGGGGGPSPAGAPGA-----AGP--------GGPGGEPGKGGAAAAAAAAAAAA 252
Query: 452 APAPAPAPFRDLASAAATEGGGGDCADAGTAGPAPPPPAPSPRPGP 497
A A A A A A GG G GP P P GP
Sbjct: 253 AAAAAAA-----AGGLAAAGGPG---QGWAPGPGPITSIPDSLGGP 290
Score = 33.1 bits (74), Expect = 0.65
Identities = 31/108 (28%), Positives = 37/108 (34%), Gaps = 8/108 (7%)
Query: 412 APAVPPAPPAQASFGAFSGPGGAPDSAFARRS-PDAVASPGAPAPAPAPFRDLASAAATE 470
A A A S G S +S A+ + PD+ PG P P P P +
Sbjct: 159 AAAAAAAAAKNGSSGKKSDSSRDDESKEAKSTDPDSTGGPG-PNPNPTP------SCGAN 211
Query: 471 GGGGDCADAGTAGPAPPPPAPSPRPGPRPPSPAEEPATCGVPEPGAAA 518
GGGG A A P P PG + A A AAA
Sbjct: 212 GGGGGGPSPAGAPGAAGPGGPGGEPGKGGAAAAAAAAAAAAAAAAAAA 259
Score = 31.6 bits (70), Expect = 1.9
Identities = 29/112 (25%), Positives = 41/112 (36%), Gaps = 10/112 (8%)
Query: 287 PSQRSGAGPQPRPGRPADKDAASCG-------PGAAVAAVERGAAGLPKASPFSVESLLS 339
P G GP P P + G PGAA G G A+ + + +
Sbjct: 192 PDSTGGPGPNPNPTPSCGANGGGGGGPSPAGAPGAAGPGGPGGEPGKGGAAAAAAAAAAA 251
Query: 340 DSPPRRKAASNAAAAAAAGLDFAPG---LPCAPRTLIGKGHFLLYPITQPLG 388
+ AA AAA G +APG + P +L G +L + +P G
Sbjct: 252 AAAAAAAAAGGLAAAGGPGQGWAPGPGPITSIPDSLGGPFASVLSSLQRPNG 303
Score = 29.3 bits (64), Expect = 9.4
Identities = 23/73 (31%), Positives = 28/73 (38%), Gaps = 10/73 (13%)
Query: 464 ASAAATEGGGGDCADAGTAGPAPPPPA--------PSPRPGPRPPSPAEEPATCGVPEPG 515
A+AAA G G +D+ + + P P P P P A G G
Sbjct: 163 AAAAAKNGSSGKKSDSSRDDESKEAKSTDPDSTGGPGPNPNPTPSCGANGGGGGGPSPAG 222
Query: 516 A--AAGPSPPEGE 526
A AAGP P GE
Sbjct: 223 APGAAGPGGPGGE 235
>gi|126116581 retina and anterior neural fold homeobox [Homo
sapiens]
Length = 346
Score = 106 bits (265), Expect = 5e-23
Identities = 90/263 (34%), Positives = 107/263 (40%), Gaps = 67/263 (25%)
Query: 62 CAAAASVVNPTPLLPAACGVGGDGQPFKLSDSGDPDKESPGCKRRRTRTNFTGWQLEELE 121
C P+P LP G KLS+ P K K RR RT FT +QL ELE
Sbjct: 102 CPKEPGEARPSPGLPVGPATG----EAKLSEEEQPKK-----KHRRNRTTFTTYQLHELE 152
Query: 122 KAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKKENTKKGPGRPAHNSHPTT 181
+AF +SHYPDV+ RE LA +++L E RVQVWFQNRRAKWR++E
Sbjct: 153 RAFEKSHYPDVYSREELAGKVNLPEVRVQVWFQNRRAKWRRQE----------------- 195
Query: 182 CSGEPMDPEEIARKELEKMEKKKRKHEKKLLKSQGRHLHSPGGLSLHSAPSSDSDSGGGG 241
K+E K + L S R S L + P S GG
Sbjct: 196 -----------------KLEVSSMKLQDSPLLSFSRSPPSATLSPLGAGPGSGGGPAGGA 238
Query: 242 LSPE----PPEPPPPAAK-------GPGAHASGAAGTAPAPPGEPPAPGTCDPAFYPSQR 290
L E PP P A GP A + A+ T P PP P F S
Sbjct: 239 LPLESWLGPPLPGGGATALQSLPGFGPPAQSLPASYTPPPPP----------PPFLNSPP 288
Query: 291 SGAGPQPRPGRPADKDAASCGPG 313
G G QP P + CGPG
Sbjct: 289 LGPGLQPLAPPP---PSYPCGPG 308
Score = 35.8 bits (81), Expect = 0.100
Identities = 23/55 (41%), Positives = 27/55 (49%), Gaps = 6/55 (10%)
Query: 476 CADAGTAGPAP-PPPAPSPRP---GPRPPSPAEEPATCGVPEPGAAAGPSPPEGE 526
C A G P PPPAP+P P PRP P +EP P PG GP+ E +
Sbjct: 73 CPKAPEEGSEPSPPPAPAPAPEYEAPRPYCP-KEPGEAR-PSPGLPVGPATGEAK 125
Score = 30.8 bits (68), Expect = 3.2
Identities = 30/100 (30%), Positives = 38/100 (38%), Gaps = 23/100 (23%)
Query: 434 APDSAFARRSPDAVASP--------GAPAPAPAPFRDL---------ASAAATEGGGGDC 476
+P +F+R P A SP G PA P A+A + G G
Sbjct: 207 SPLLSFSRSPPSATLSPLGAGPGSGGGPAGGALPLESWLGPPLPGGGATALQSLPGFGPP 266
Query: 477 ADAGTAGPAPPPPAP----SP--RPGPRPPSPAEEPATCG 510
A + A PPPP P SP PG +P +P CG
Sbjct: 267 AQSLPASYTPPPPPPPFLNSPPLGPGLQPLAPPPPSYPCG 306
>gi|24497589 aristaless related homeobox [Homo sapiens]
Length = 562
Score = 104 bits (260), Expect = 2e-22
Identities = 104/325 (32%), Positives = 138/325 (42%), Gaps = 75/325 (23%)
Query: 51 PFSIDGLLGGSCAAAASV----VNPTP--LLPAACGVGGDGQPFK-LSDSGDPDKESPGC 103
P + G + + AAA + ++P LL G DG+ LS D ++
Sbjct: 267 PVAATGAVAAAAAAAVATEGGELSPKEELLLHPEDAEGKDGEDSVCLSAGSDSEEGLLKR 326
Query: 104 KRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKK 163
K+RR RT FT +QLEELE+AF ++HYPDVF RE LA+RLDL E+RVQVWFQNRRAKWRK+
Sbjct: 327 KQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKR 386
Query: 164 ENTKKGPGRPAHNSHPTTCSGEPMDPEEIARKELEKMEKKKRKHEKKLLKSQGRHLHSPG 223
E + +HP G P PG
Sbjct: 387 E-------KAGAQTHP---PGLPF----------------------------------PG 402
Query: 224 GLSLHSAPSSDSDSGGGGLSPEPPEPPPPAAKGPGAHASGAAGTAPAPPGEPPAPGTCDP 283
LS S D+ SP PP P A + AA A A P PP PG+
Sbjct: 403 PLSATHPLSPYLDA-----SPFPPHHPAL----DSAWTAAAAAAAAAFPSLPPPPGS--- 450
Query: 284 AFYPSQRSGAGPQPRPGRPADKDAASCGPG--------AAVAAVERGAAGLPKASPFSVE 335
A P + G G + A P A + + AA L + +P +VE
Sbjct: 451 ASLPPSGAPLGLSTFLGAAVFRHPAFISPAFGRLFSTMAPLTSASTAAALLRQPTP-AVE 509
Query: 336 SLLSD---SPPRRKAASNAAAAAAA 357
++ + P AA A++ AA
Sbjct: 510 GAVASGALADPATAAADRRASSIAA 534
Score = 45.4 bits (106), Expect = 1e-04
Identities = 46/134 (34%), Positives = 56/134 (41%), Gaps = 32/134 (23%)
Query: 366 PCAPRTLIGKGHFLLYPITQPLGFLVPQAALKGGAGLEPAPKDAPPAPAVPPAPPAQASF 425
PC R L+G L P+T P+ A++G AP +A +PP
Sbjct: 38 PCKMR-LLGAAQSLPAPLTSRAD---PEKAVQGSPKSSSAPFEAELH--LPP------KL 85
Query: 426 GAFSGPGGAPDSAFARRSPDAVASPGAPAPAPAPFRDLASAAATEGGGGDCADAGTAGPA 485
GPGG R A A+ A A A A+AAAT A AG G A
Sbjct: 86 RRLYGPGGG------RLLQGAAAAAAAAAAA-------AAAAAT-------ATAGPRGEA 125
Query: 486 PPPPAPSPRPGPRP 499
PPPP P+ RPG RP
Sbjct: 126 PPPPPPTARPGERP 139
Score = 33.5 bits (75), Expect = 0.50
Identities = 41/134 (30%), Positives = 54/134 (40%), Gaps = 23/134 (17%)
Query: 217 RHLHSPGGLSL----------HSAPSSDSDSGGGGLSPEPPEPPPPAAK------GPGAH 260
R L+ PGG L +A ++ + + G E P PPPP A+ G GA
Sbjct: 86 RRLYGPGGGRLLQGAAAAAAAAAAAAAAAATATAGPRGEAPPPPPPTARPGERPDGAGAA 145
Query: 261 ASGAAGTAPA--PPGEPPAPGTCDPAFYPSQRSGAGPQPRPGRPADKDAASCGPGAAVAA 318
A+ AA A A AP + +GA P P PA + GPG
Sbjct: 146 AAAAAAAAAAWDTLKISQAPQVSISRSKSYRENGAPFVPPP--PALDELG--GPGGVTHP 201
Query: 319 VER-GAAGLPKASP 331
ER G AG P ++P
Sbjct: 202 EERLGVAGGPGSAP 215
>gi|55743092 aristaless-like homeobox 4 [Homo sapiens]
Length = 411
Score = 103 bits (256), Expect = 5e-22
Identities = 56/120 (46%), Positives = 69/120 (57%), Gaps = 17/120 (14%)
Query: 62 CAAAASVVNPTPLLPAACGVGGDGQPFKLSDSG-----------------DPDKESPGCK 104
C A S + L P + VG D + ++G D ES K
Sbjct: 154 CYAKESSLGEPELPPDSDTVGMDSSYLSVKEAGVKGPQDRASSDLPSPLEKADSESNKGK 213
Query: 105 RRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKKE 164
+RR RT FT +QLEELEK F ++HYPDV+ RE LA+R DL E+RVQVWFQNRRAKWRK+E
Sbjct: 214 KRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRE 273
Score = 30.0 bits (66), Expect = 5.5
Identities = 17/65 (26%), Positives = 27/65 (41%)
Query: 461 RDLASAAATEGGGGDCADAGTAGPAPPPPAPSPRPGPRPPSPAEEPATCGVPEPGAAAGP 520
+DLA+ + G + P+ P P P P+P P+ P +P A
Sbjct: 71 QDLATPLESGAGARGSFNKFQPQPSTPQPQPPPQPQPQQQQPQPQPPAQPHLYLQRGACK 130
Query: 521 SPPEG 525
+PP+G
Sbjct: 131 TPPDG 135
>gi|113204604 aristaless-like homeobox 3 [Homo sapiens]
Length = 343
Score = 100 bits (250), Expect = 3e-21
Identities = 80/233 (34%), Positives = 100/233 (42%), Gaps = 57/233 (24%)
Query: 73 PLLPAACGVGGDGQPFKLSDSGDPDKES------PGC-----------KRRRTRTNFTGW 115
P LP C G P L S P S PG K+RR RT F+ +
Sbjct: 104 PQLPLDCRGGPRDGPSNLQGSPGPCLASLHLPLSPGLPDSMELAKNKSKKRRNRTTFSTF 163
Query: 116 QLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKKENTKKGPGRPAH 175
QLEELEK F ++HYPDV+ RE LALR DL E+RVQVWFQNRRAKWRK+E G+
Sbjct: 164 QLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRKRERY----GKIQE 219
Query: 176 NSHPTTCSGE-PMDPEEIARKELEKMEKKKRKHEKKLLKSQGRHLHSPGGLSLHSAPSSD 234
+P T + + + P + +L+ SL ++P S
Sbjct: 220 GRNPFTAAYDISVLPRTDSHPQLQN--------------------------SLWASPGSG 253
Query: 235 SDSGGGGLSPEP-PEPPPPAAKGPGAHASGAAGTAPAPPGEPPAPGTCDPAFY 286
S G +SPE P P P +G G PAP P Y
Sbjct: 254 SPGGPCLVSPEGIPSPCMSPYSHPHGSVAGFMGV--------PAPSAAHPGIY 298
Score = 30.8 bits (68), Expect = 3.2
Identities = 39/139 (28%), Positives = 46/139 (33%), Gaps = 38/139 (27%)
Query: 245 EPPEPPPPAAKGPGAHASGAAGTAPAPPGEP-----PAPGTCDPAFYPSQRSGAGPQPRP 299
EPP P A P H PAPP P PA G +P P P
Sbjct: 24 EPPGPQGTPAAAPHLH--------PAPPRGPRLTRFPACGPLEPYL-----------PEP 64
Query: 300 GRPADKDAASCGPGAAV---------AAVER---GAAGLPKASPFSVESLLSDSPPRRKA 347
+P K GPG A+ A E AA P+ P D P +
Sbjct: 65 AKPPAKYLQDLGPGPALNGGHFYEGPAEAEEKTSKAASFPQL-PLDCRGGPRDGPSNLQ- 122
Query: 348 ASNAAAAAAAGLDFAPGLP 366
S A+ L +PGLP
Sbjct: 123 GSPGPCLASLHLPLSPGLP 141
Score = 29.3 bits (64), Expect = 9.4
Identities = 14/36 (38%), Positives = 15/36 (41%)
Query: 493 PRPGPRPPSPAEEPATCGVPEPGAAAGPSPPEGEEL 528
P PGP S E P G P P+PP G L
Sbjct: 13 PAPGPYVASGDEPPGPQGTPAAAPHLHPAPPRGPRL 48
>gi|154813201 cartilage paired-class homeoprotein 1 [Homo sapiens]
Length = 326
Score = 100 bits (248), Expect = 4e-21
Identities = 50/85 (58%), Positives = 61/85 (71%), Gaps = 1/85 (1%)
Query: 81 VGGDGQPFKLSDSGDP-DKESPGCKRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALA 139
V G + +L + GD D K+RR RT FT QLEELEK F ++HYPDV++RE LA
Sbjct: 107 VKGMQEKGELDELGDKCDSNVSSSKKRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLA 166
Query: 140 LRLDLVESRVQVWFQNRRAKWRKKE 164
LR +L E+RVQVWFQNRRAKWRK+E
Sbjct: 167 LRTELTEARVQVWFQNRRAKWRKRE 191
>gi|34365783 visual system homeobox 2 [Homo sapiens]
Length = 361
Score = 99.0 bits (245), Expect = 1e-20
Identities = 44/61 (72%), Positives = 53/61 (86%)
Query: 104 KRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKK 163
K+RR RT FT +QLEELEKAFNE+HYPDV+ RE LA++ +L E R+QVWFQNRRAKWRK+
Sbjct: 147 KKRRHRTIFTSYQLEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWRKR 206
Query: 164 E 164
E
Sbjct: 207 E 207
>gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens]
Length = 325
Score = 99.0 bits (245), Expect = 1e-20
Identities = 66/156 (42%), Positives = 83/156 (53%), Gaps = 19/156 (12%)
Query: 28 LGHHHVYELAGHQLQSAAAAASVPFSIDGLLGGSCAAAASVVNPTPLLPAACGVGGDGQP 87
LG EL GH+ ++ V S G G A + V LLP P
Sbjct: 12 LGMKDAAELLGHR-EAVKCRLGVGGSDPGGHPGDLAPNSDPVEGATLLPGEDITTVGSTP 70
Query: 88 FKLSDSG-DPDKESPGC----------------KRRRTRTNFTGWQLEELEKAFNESHYP 130
L+ S DPDK+ PG K++R RT FT QL ELE++F ++HYP
Sbjct: 71 ASLAVSAKDPDKQ-PGPQGGPNPSQAGQQQGQQKQKRHRTRFTPAQLNELERSFAKTHYP 129
Query: 131 DVFMREALALRLDLVESRVQVWFQNRRAKWRKKENT 166
D+FMRE LALR+ L ESRVQVWFQNRRAKW+K++ T
Sbjct: 130 DIFMREELALRIGLTESRVQVWFQNRRAKWKKRKKT 165
>gi|14149760 orthopedia homeobox [Homo sapiens]
Length = 325
Score = 99.0 bits (245), Expect = 1e-20
Identities = 66/156 (42%), Positives = 83/156 (53%), Gaps = 19/156 (12%)
Query: 28 LGHHHVYELAGHQLQSAAAAASVPFSIDGLLGGSCAAAASVVNPTPLLPAACGVGGDGQP 87
LG EL GH+ ++ V S G G A + V LLP P
Sbjct: 12 LGMKDAAELLGHR-EAVKCRLGVGGSDPGGHPGDLAPNSDPVEGATLLPGEDITTVGSTP 70
Query: 88 FKLSDSG-DPDKESPGC----------------KRRRTRTNFTGWQLEELEKAFNESHYP 130
L+ S DPDK+ PG K++R RT FT QL ELE++F ++HYP
Sbjct: 71 ASLAVSAKDPDKQ-PGPQGGPNPSQAGQQQGQQKQKRHRTRFTPAQLNELERSFAKTHYP 129
Query: 131 DVFMREALALRLDLVESRVQVWFQNRRAKWRKKENT 166
D+FMRE LALR+ L ESRVQVWFQNRRAKW+K++ T
Sbjct: 130 DIFMREELALRIGLTESRVQVWFQNRRAKWKKRKKT 165
>gi|14249388 retina and anterior neural fold homeobox 2 [Homo
sapiens]
Length = 184
Score = 98.6 bits (244), Expect = 1e-20
Identities = 46/79 (58%), Positives = 57/79 (72%)
Query: 96 PDKESPGCKRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQN 155
P +E+P K RR RT FT +QL +LE+AF SHYPDV+ RE LA ++ L E RVQVWFQN
Sbjct: 18 PGEEAPKKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVRVQVWFQN 77
Query: 156 RRAKWRKKENTKKGPGRPA 174
RRAKWR++E + G G A
Sbjct: 78 RRAKWRRQERLESGSGAVA 96
>gi|46249382 paired-like homeobox 2a [Homo sapiens]
Length = 284
Score = 98.2 bits (243), Expect = 2e-20
Identities = 71/216 (32%), Positives = 89/216 (41%), Gaps = 48/216 (22%)
Query: 104 KRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKK 163
K+RR RT FT QL+ELE+ F E+HYPD++ RE LAL++DL E+RVQVWFQNRRAK+RK+
Sbjct: 89 KQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQ 148
Query: 164 E---NTKKGPGRPAHNSHPTTCSGEPMDPEEIARKELEKMEKKKRKHEKKLLKSQGRHLH 220
E + K G CS E D +E
Sbjct: 149 ERAASAKGAAGAAGAKKGEARCSSEDDDSKEST--------------------------- 181
Query: 221 SPGGLSLHSAPSSDSDSGGGGLSPEPPEPPPPAAKGPGAHASGAAGTAPAPPGEPPAPGT 280
+P+ DS + P PP P P S + PG P P
Sbjct: 182 --------CSPTPDS-------TASLPPPPAPGLASPRLSPSPLPVALGSGPGPGPGPQP 226
Query: 281 CDPAFYPSQRSGAGPQPRPGRPADKDA---ASCGPG 313
A + G G P G A A GPG
Sbjct: 227 LKGALWAGVAGGGGGGPGAGAAELLKAWQPAESGPG 262
Score = 37.0 bits (84), Expect = 0.045
Identities = 39/128 (30%), Positives = 43/128 (33%), Gaps = 19/128 (14%)
Query: 394 AALKGGAGLEPAPK---------DAPPAPAVPPAPPAQASFGAFSGPGGAPDSAFARRSP 444
A+ KG AG A K D P P + AS PG A P
Sbjct: 152 ASAKGAAGAAGAKKGEARCSSEDDDSKESTCSPTPDSTASLPPPPAPGLASPRLSPSPLP 211
Query: 445 DAVASPGAPAPAPAPFRDLASAAATEGGGGDCADAGTA----GPAPPPPAPSPRPG---- 496
A+ S P P P P + A A GGGG AG A P P P G
Sbjct: 212 VALGSGPGPGPGPQPLKG-ALWAGVAGGGGGGPGAGAAELLKAWQPAESGPGPFSGVLSS 270
Query: 497 -PRPPSPA 503
R P PA
Sbjct: 271 FHRKPGPA 278
>gi|11056038 visual system homeobox 1 isoform a [Homo sapiens]
Length = 365
Score = 95.1 bits (235), Expect = 1e-19
Identities = 43/61 (70%), Positives = 52/61 (85%)
Query: 104 KRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKK 163
K+RR RT FT QLEELEKAF+E+HYPDV+ RE LA++ +L E R+QVWFQNRRAKWRK+
Sbjct: 163 KKRRHRTVFTAHQLEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKR 222
Query: 164 E 164
E
Sbjct: 223 E 223
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 95.1 bits (235), Expect = 1e-19
Identities = 101/363 (27%), Positives = 123/363 (33%), Gaps = 32/363 (8%)
Query: 167 KKGPGRPAHNSHPTTCSGEPMDPE-EIARKELEKMEKKKRKHEKKLLKSQGRHLHSPGGL 225
K GP P+ PT + P P+ A K K P G
Sbjct: 997 KGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGA 1056
Query: 226 SLHSAPSSDSDSGGGGLSPEPPEPPPPAAKGPGAHASGAAGTAPAPPGEPPAPGTCDPAF 285
A + S GG P PPAA P A P+P G P P A
Sbjct: 1057 PTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPAT---PSPKGAPMPPA----AT 1109
Query: 286 YPSQRSGAGPQPRPGRPADKDAASCGP-GAAVAAVERGAAGLPKASPFSVESLLSDSPPR 344
PS + G P G P A P G +GA P A+P S + L+ PP+
Sbjct: 1110 PPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPK 1169
Query: 345 RKAASNAAAAAAAGLDFA-PGLPCAPRTLIGKGHFLLYPITQPLGFLVPQAALKGGAGLE 403
+ AA + A P AP T P P + KGG
Sbjct: 1170 GAPTTPAATPPSPKGGLATPSPKGAPTT----------PAATP-------PSPKGGLAT- 1211
Query: 404 PAPKDAPPAPAVPPAPPAQASFGAFSGPGGAPDSAFARRSPDAVASPGAPAPAPAPFRDL 463
P+PK AP PA P P A P GAP + A P P P P AP
Sbjct: 1212 PSPKGAPTTPAATPPSPKGGL--ATPSPKGAPTTP-AATPPSPKGGPATPPPKGAPTPPA 1268
Query: 464 ASAAATEGGGGDCADAGTAGPAP-PPPAPSPRPGPRPPSPAEEPATCGVPEPGAAAGPSP 522
A+ + +GG G PA PP+P P PP A P P P + G P
Sbjct: 1269 ATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPP 1328
Query: 523 PEG 525
P+G
Sbjct: 1329 PKG 1331
Score = 89.0 bits (219), Expect = 1e-17
Identities = 105/372 (28%), Positives = 125/372 (33%), Gaps = 65/372 (17%)
Query: 167 KKGPGRPAHNSHPTTCSGEPMDPEEIARKELEKMEKKKRKHEKKLLKSQGRHLHSPGGLS 226
K GP P+ PT + P P+ G SP G
Sbjct: 1068 KGGPATPSLKGAPTPPAATPPSPKG------------------------GPATPSPKGAP 1103
Query: 227 LHSAPSSDSDSGGGGLSPEPPEPPPPAAKGPGAHASGAAGTAPAPPGEPPAPGTCDPAFY 286
+ A + S GG P P PAA P A P P G P P A
Sbjct: 1104 MPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLAT---PPPKGAPTTPA----ATP 1156
Query: 287 PSQRSGAGPQPRPGRPADKDAASCGPGAAVAAVE-RGAAGLPKASPFSVES-LLSDSP-- 342
PS + G P G P A P +A +GA P A+P S + L + SP
Sbjct: 1157 PSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKG 1216
Query: 343 -PRRKAASNAAAAAAAGLDFAPGLPCAPRTL--IGKGHFLLYPITQPLGFLVPQAA---- 395
P AA+ + G P P KG P P G P AA
Sbjct: 1217 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPP---PKGAPTPPAATPPS 1273
Query: 396 LKGGAGLEPAPKDAPPAPAVPPAPPAQASFGAFSGPGGAPDSAFARRSPDAVASPGAPAP 455
LKGG P PA PP+P A S P GAP A P SPG P P
Sbjct: 1274 LKGGLATPPHKGAPNPAVVTPPSPKGGP---ATSPPKGAPTPP-AATPPSPKGSPGTPPP 1329
Query: 456 APAPFRDLASAAATEGG-----------GGDCADAGTAGPAPPPPAPSPRPGP--RPPSP 502
AP + + +G GG + GP PP PS + GP PPSP
Sbjct: 1330 KGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSP 1389
Query: 503 AEEPATCGVPEP 514
PA +P P
Sbjct: 1390 KRGPA---IPSP 1398
Score = 80.1 bits (196), Expect = 5e-15
Identities = 96/338 (28%), Positives = 124/338 (36%), Gaps = 43/338 (12%)
Query: 221 SPGGLSLHSAPSSDSDSGGGGLSPEPPEPPPPAAKGPGAHASGAAGTAPAPPGEPPAPGT 280
SP G A + S GG +P P P P A P + G A P+P G P P
Sbjct: 935 SPKGAPTPPAATPPSPKGGPA-TPSPKWAPTPPAATPPSPKGGPA--TPSPKGAPTPPA- 990
Query: 281 CDPAFYPSQRSG-AGPQPRPGRPADKDAASCGPGAAVAAV--ERGAAGLPKASPFSVESL 337
A PS + G A P P+ G P P + AA +GA+ P A+P S +
Sbjct: 991 ---ATPPSPKGGPATPSPK-GAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGS 1046
Query: 338 LSDSPPRRKAASNAAAA--------AAAGLDFAPGLPCAPRTLIGKGHFLLYPITQPLGF 389
+ +P + A + AA A L AP P A G P P+
Sbjct: 1047 PAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPP 1106
Query: 390 LVPQAALKGGAGLEP------APKDAPPAP----AVPP----------APPAQASFGAFS 429
+ KGG P P PP+P A PP PP+ A
Sbjct: 1107 AATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATP 1166
Query: 430 GPGGAPDSAFARRSPDAVASPGAPAPAPAPFRDLASAAATEGGGGDCADAGTAGPAPPPP 489
P GAP + A P P+P AP A+ + +GG + G A P
Sbjct: 1167 PPKGAPTTP-AATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKG-APTTPAAT 1224
Query: 490 APSPRPGPRPPSPAEEPATCGVPEPGAAAGPS--PPEG 525
PSP+ G PSP P T P GP+ PP+G
Sbjct: 1225 PPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKG 1262
Score = 74.3 bits (181), Expect = 3e-13
Identities = 100/342 (29%), Positives = 125/342 (36%), Gaps = 59/342 (17%)
Query: 235 SDSGGGGLSPEPPEPPPPAAKGPGAHASGAAGT-----APAPPG-EPPAP-GTCD-PAFY 286
S GG SP P PPAA P G+ GT AP PP PP+P GT PA
Sbjct: 1296 SPKGGPATSPPKGAPTPPAATPPSP--KGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATT 1353
Query: 287 PSQRSGA-------GPQPRPGRPADKDAASCGPGAAVAAVERGAA-GLPKASPFS--VES 336
PS + G GP P P+ K GP + +RG A PK P S V
Sbjct: 1354 PSSKGGPTTPSSKEGPTPPAATPSHKG----GPAMTPPSPKRGPAIPSPKGDPTSPAVIP 1409
Query: 337 LLSDSPPRRKAASNAAAAAAAG-----------LDFAPGLPC---APRTLIGKGHFLLYP 382
L P AA + G L AP P T KG L
Sbjct: 1410 LSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPA 1469
Query: 383 ITQPLGFLVP---QAALKGG---AGLEPAPKDAPPAPAVPPAPPAQ--ASFGAFSGPGGA 434
+T P P Q A A PAP AP PAV P+ P + A+ + P
Sbjct: 1470 VTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAP 1529
Query: 435 PDSAFARRSPDAVASPGAPAP----APAPFRDLASAAATEGGGGDCADAGTAGPAPPPP- 489
+ ++++P +A A P P+P + A E + ++ PA P
Sbjct: 1530 TATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPST 1589
Query: 490 ---APSPR-----PGPRPPSPAEEPATCGVPEPGAAAGPSPP 523
APSP+ P PSP E P V P GP+ P
Sbjct: 1590 YKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATP 1631
Score = 64.7 bits (156), Expect = 2e-10
Identities = 85/318 (26%), Positives = 111/318 (34%), Gaps = 55/318 (17%)
Query: 241 GLSPEPPEPPPPAAKGPGAHASGAAG-TAPAPPGEPPAPGTCDPAFYPSQRSGAGPQPRP 299
G+S P PP KG + ++P P E +F S+ S A P
Sbjct: 798 GVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHS-P 856
Query: 300 GRPADKDAASCGPGAAVAAVERGAAGLPKASP--------FSVESLLSDSPPRRKAASNA 351
P+ K A + P A +G PK +P F E + +P + A S
Sbjct: 857 TPPSPKGAPT--PSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMT 914
Query: 352 AAAA--AAGLDFAPGLPCAPRTLIGKGHFLLYPITQPLGFLVPQAAL----KGGAGLEPA 405
+++ A G+P +P P G P AA KGG P+
Sbjct: 915 SSSPKKARATPAPKGIPASP---------------SPKGAPTPPAATPPSPKGGPAT-PS 958
Query: 406 PKDAPPAPAVPPAPPAQASFGAFSGPGGAPDSAFARRSPDAVASPGAPAPAPAPFRDLAS 465
PK AP PA PP+ A P GAP A P P P+P AP +
Sbjct: 959 PKWAPTPPAA--TPPSPKGGPATPSPKGAPTPP-AATPPSPKGGPATPSPKGAPTPPAVT 1015
Query: 466 AAATEG--GGGDCADAGTAGPAPPPPAPSPRPGPRP-------------PSPAEEPAT-- 508
+ +G + PA PP+P P P PSP PAT
Sbjct: 1016 PPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPS 1075
Query: 509 -CGVPEPGAAAGPSPPEG 525
G P P AA PSP G
Sbjct: 1076 LKGAPTPPAATPPSPKGG 1093
Score = 63.9 bits (154), Expect = 3e-10
Identities = 85/307 (27%), Positives = 117/307 (38%), Gaps = 74/307 (24%)
Query: 234 DSDSGGGGLSPEPPEPPPPAAKGPGAHASGAA-GT------APAPPGEPPAPGTCDPAFY 286
D S L+P P + GA A+ ++ GT +P+P G +P T P
Sbjct: 752 DGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRP--- 808
Query: 287 PSQRSGAGPQPRPGR---PADKDAASCGPGAAVAAVERGAAGLPKASPFSVESLLSDSPP 343
P+++ AGP G P AS P +++ + S S + S +PP
Sbjct: 809 PTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSF---------QGSKDSPATTHSPTPP 859
Query: 344 RRKAASNAAAAAAAGLDFAPGLPCAPRTLIGKGHFLLYPITQPLGFLVPQAALKGGAGLE 403
K A +A P +P+ + L P P +V
Sbjct: 860 SPKGAPTPSAVT----------PLSPKGVT------LPPKETPTPSVVNL---------- 893
Query: 404 PAPKDAPPAPAVPPAPPAQASFGAFSGPGGAPDSAFARRSPDAVASPGAPAPAPAPFRDL 463
P PK+ P PA AP A S +P A A +P + P +P+P AP
Sbjct: 894 PFPKEGPATPAPKQAP-------ALSMTSSSPKKARATPAPKGI--PASPSPKGAPTPPA 944
Query: 464 ASAAATEGGGGDCADAGTAGP--APPPPA---PSPRPGPRPPSPAEEPATCGVPEPGAAA 518
A+ + +GG T P AP PPA PSP+ GP PSP G P P AA
Sbjct: 945 ATPPSPKGG------PATPSPKWAPTPPAATPPSPKGGPATPSPK------GAPTPPAAT 992
Query: 519 GPSPPEG 525
PSP G
Sbjct: 993 PPSPKGG 999
Score = 59.7 bits (143), Expect = 6e-09
Identities = 97/381 (25%), Positives = 131/381 (34%), Gaps = 65/381 (17%)
Query: 167 KKGPGRPAHNSHPTTCSGEPMDPEEIARKELEKMEKKKRKHEKKLLKSQGRHLHSPG--G 224
K+GP P+ PT+ + P+ P++ + + E S+G L P
Sbjct: 1390 KRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTR--------EGAATPSKG-DLTPPAVTP 1440
Query: 225 LSLHSAPSSDSDSGGGGLS-------------PEPPEPPPPAAKGPGAHASGAAGTAPAP 271
+SL AP++ + GG P P EPP P + A T PAP
Sbjct: 1441 VSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPAT-PAP 1499
Query: 272 PGEPPAPGTCDPAFYPSQRSGAGPQPRPGRPADKDAASCGPGAAVAAVERGAAGLPKASP 331
G P PA PS P+ P P+ + P A + + + A PK +
Sbjct: 1500 MGAPTL-----PAVIPS-----SPKEVPATPSSR-RDPIAPTATLLSKKTPATLAPKEA- 1547
Query: 332 FSVESLLSDSPPRRKAASNAAAAAAAGLDFAPGLPCAPRTLIGKGHFLLYPITQPLGFLV 391
++ SP + A A A P A KG P L+
Sbjct: 1548 LIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKG------APSPKELLI 1601
Query: 392 PQAALKGGAGLEPAPKDAPPAPAVPPAPPAQASFGAFSGPGGAPDS-----AFARRSPDA 446
P A P+PK+AP PAV P P + A P G P S + + SP +
Sbjct: 1602 PPAV------TSPSPKEAPTPPAVTPPSPEKGP--ATPAPKGTPTSPPVTPSSLKDSPTS 1653
Query: 447 VASPGAPAPAPAPFRDLASAAATEGGGGDCADAGTAGPAP---PPPAPSPRPGPR-PPSP 502
AS A P AS G PAP P R GP+ S
Sbjct: 1654 PASVTCKMGATVP---QASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSS 1710
Query: 503 AEEPATCGVPEPGAAAGPSPP 523
A P C P+P A G P
Sbjct: 1711 ATSPPIC--PDPSAKNGSKGP 1729
Score = 47.8 bits (112), Expect = 3e-05
Identities = 79/314 (25%), Positives = 106/314 (33%), Gaps = 42/314 (13%)
Query: 243 SPEPPEPPPPAAKGPGAHASGAAGTAPAPPGEPPAPGTCDPAFYPSQRSGAG-------- 294
SP P E P P A P + G A PAP G P +P + S S A
Sbjct: 1607 SPSPKEAPTPPAVTPPSPEKGPA--TPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGAT 1664
Query: 295 -PQPRPGRPADKDAASCGPGAAVAAVERGAAGLPKASPF---------SVESLLSDSPP- 343
PQ G PA K GP A + A P+++P + + SPP
Sbjct: 1665 VPQASKGLPAKK-----GPTALKEVL---VAPAPESTPIITAPTRKGPQTKKSSATSPPI 1716
Query: 344 -RRKAASNAAAAAAAGLDFAPGLPC---APRTLIGK--GHFLLYPITQPLGFLVPQAALK 397
+A N + + + AP LP + +T GK H P+ P L
Sbjct: 1717 CPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPES--KASTPLT 1774
Query: 398 GGAGLEPAPKDAPPAPAVPPAPPAQASFGAFSGPGGAPDSAFARRSPDAVASPGAPAPAP 457
A + PK + + P+PP P P F SP V + AP
Sbjct: 1775 AAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAP 1834
Query: 458 APFRDLASAAATEGGGGDCADAGTAGPAPPPPAPSPRPGPRPPSPAEEPATCGVPEPG-- 515
A +L E G P P + P P A++P T G
Sbjct: 1835 ADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGI---PVPTPSAKQPVTKNNKGSGTE 1891
Query: 516 AAAGPSPPEGEELD 529
+ + S PE EE D
Sbjct: 1892 SDSDESVPELEEQD 1905
Score = 30.4 bits (67), Expect = 4.2
Identities = 66/292 (22%), Positives = 95/292 (32%), Gaps = 47/292 (16%)
Query: 231 PSSDSDSGGGGLSPEPPEPPPPAAKGPGAHASGAAGTAPAPPGEPPAPGTCDPAFYPSQR 290
P S + S L P PPP + P AA A P P+ P P +
Sbjct: 27 PMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPS--PSTIASTPLEVPFPQ 84
Query: 291 SGAGPQPRPGRPADKDAAS---CGPGAAVAAVERGAAGLPKASPFSVESLLSDSPPRRKA 347
S +G G + GP + AA+ A P +P +++ S S P
Sbjct: 85 SSSGTALPLGTAPEAPTFLPNLIGPPISPAAL---ALASPMIAP-TLKGTPSSSAPLALV 140
Query: 348 ASNAAAAAAAGLDFAPGLPCAPRTLIGKGHFLLYPITQPLGFLVPQAALKGGAGLEPAPK 407
A A + F P L +P ++ + ++ P+ P+ L P
Sbjct: 141 AL-APHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKT------NLNKVPS 193
Query: 408 DAPPAPAVPPAPP--------------AQASFGAFSGPGGAPDSAFARRSP--------D 445
+ P P P+PP A G S P P + A SP
Sbjct: 194 EVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISS 253
Query: 446 AVASPGAP------APAPAPFRDLASAAATEGGGGDCADAGTAGPAPPPPAP 491
+ SP P P P A + +T+ + TAGP PP P
Sbjct: 254 VLISPQNPGSLSLKGPVSPP---AALSLSTQSLPVVTSSQKTAGPNTPPDFP 302
>gi|22218349 diencephalon/mesencephalon homeobox 1 isoform b [Homo
sapiens]
Length = 382
Score = 94.4 bits (233), Expect = 2e-19
Identities = 78/264 (29%), Positives = 110/264 (41%), Gaps = 26/264 (9%)
Query: 104 KRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKK 163
K+RR+RT FT QLE LEK F ++HYPDV MRE LA+ +L E+RVQVWF+NRRAK+RKK
Sbjct: 70 KQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKK 129
Query: 164 ENT----KKGPGRPAHNSHPTTCSGEPMDPEEIARKELEKMEKKKRKHEKKLLKSQGRHL 219
+ + + + A SH + P ++ ++ ++ E HL
Sbjct: 130 QRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAE--------LHL 181
Query: 220 HSPGGLSLHSAPSSDSDSGGGGLSPEPPEPPPPAAKGPGAHASGAAGTAPAPPGEPPAPG 279
+ SAP D P P A K PGA + G +P + P
Sbjct: 182 SLSEQSASESAPEDQPDREE---DPRAGAEDPKAEKSPGADSKGLGCKRGSPKADSPGSL 238
Query: 280 TCDPAFYPSQRSGAGPQPRPGRPADKDAASCGPGAAVAAVERGAAGLPKASPFSVESLLS 339
T P P G + S P + E+ + + S
Sbjct: 239 TITPV-----------APGGGLLGPSHSYSSSPLSLFRLQEQFRQHMAATNNLVHYSSFE 287
Query: 340 DSPPRRKAASNAAAAAAAGLDFAP 363
P AA+ AAA G++ AP
Sbjct: 288 VGGPAPAAAAAAAAVPYLGVNMAP 311
>gi|27436936 diencephalon/mesencephalon homeobox 1 isoform a [Homo
sapiens]
Length = 377
Score = 94.4 bits (233), Expect = 2e-19
Identities = 78/264 (29%), Positives = 110/264 (41%), Gaps = 26/264 (9%)
Query: 104 KRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKK 163
K+RR+RT FT QLE LEK F ++HYPDV MRE LA+ +L E+RVQVWF+NRRAK+RKK
Sbjct: 65 KQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKK 124
Query: 164 ENT----KKGPGRPAHNSHPTTCSGEPMDPEEIARKELEKMEKKKRKHEKKLLKSQGRHL 219
+ + + + A SH + P ++ ++ ++ E HL
Sbjct: 125 QRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAE--------LHL 176
Query: 220 HSPGGLSLHSAPSSDSDSGGGGLSPEPPEPPPPAAKGPGAHASGAAGTAPAPPGEPPAPG 279
+ SAP D P P A K PGA + G +P + P
Sbjct: 177 SLSEQSASESAPEDQPDREE---DPRAGAEDPKAEKSPGADSKGLGCKRGSPKADSPGSL 233
Query: 280 TCDPAFYPSQRSGAGPQPRPGRPADKDAASCGPGAAVAAVERGAAGLPKASPFSVESLLS 339
T P P G + S P + E+ + + S
Sbjct: 234 TITPV-----------APGGGLLGPSHSYSSSPLSLFRLQEQFRQHMAATNNLVHYSSFE 282
Query: 340 DSPPRRKAASNAAAAAAAGLDFAP 363
P AA+ AAA G++ AP
Sbjct: 283 VGGPAPAAAAAAAAVPYLGVNMAP 306
>gi|4826912 paired-like homeodomain 3 [Homo sapiens]
Length = 302
Score = 93.6 bits (231), Expect = 4e-19
Identities = 82/265 (30%), Positives = 112/265 (42%), Gaps = 52/265 (19%)
Query: 94 GDPDKESPGCKRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWF 153
G P+ S K+RR RT+FT QL+ELE F + YPD+ RE +A+ +L E+RV+VWF
Sbjct: 51 GSPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWF 110
Query: 154 QNRRAKWRKKENTKKGPGRPAHNSHPTTCSGEPMDPEEIARKELEKMEKKKRKHEKKLLK 213
+NRRAKWRK+E +++ C G P
Sbjct: 111 KNRRAKWRKRERSQQA----------ELCKGSFAAP------------------------ 136
Query: 214 SQGRHLHSPGGLSLHSAPSSDSDSGGGGLSPEPPE--PPPPAAKG-PGAHASGAAGTAPA 270
GGL P + G PP+ PP AAK P A S G +
Sbjct: 137 --------LGGL----VPPYEEVYPGYSYGNWPPKALAPPLAAKTFPFAFNSVNVGPLAS 184
Query: 271 PPGEPPAPGTCDPAFYPSQRSGAGPQPRPGRPADKDAASCGPGAAVAAVERGAAGLPKAS 330
P P P + + PS + G P PG A + PG A AAV GA P AS
Sbjct: 185 QPVFSP-PSSIAASMVPSAAAAPGTVPGPG--ALQGLGGGPPGLAPAAVSSGAVSCPYAS 241
Query: 331 PFSVESLLSDSPPRRKAASNAAAAA 355
+ + + SP + N++ A+
Sbjct: 242 AAAAAAAAASSPYVYRDPCNSSLAS 266
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 93.2 bits (230), Expect = 5e-19
Identities = 104/339 (30%), Positives = 122/339 (35%), Gaps = 51/339 (15%)
Query: 208 EKKLLKSQGRHLHSPGGLSLHSAPSSDSDSGGGGLSPEPPEPPPPAAKGPGAHASGAAGT 267
E +L S H H L+ + + +G G P A GP A A GA G
Sbjct: 30 ESQLAASAAHHHH----LAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGA 85
Query: 268 APAPPGEPPAPGTCDPAFYPSQRSG----------AGPQPRPGR---PADKDAASCGPGA 314
AP EPP G P QR G AGP P + P + A SC P
Sbjct: 86 AP----EPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVP 141
Query: 315 AVAAVERGAAGLPKASPFSVESLLSDSPPRRKAASNAAAAAAAGLDFAPGLPCAP---RT 371
A AAV G P+ +P + +A G PG P P +T
Sbjct: 142 AAAAVAAG----PEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQT 197
Query: 372 LIGKGHFL-LYPITQPLGFLVPQAALKGGAGLEPAPKDAPPAPAVPPAPPAQASFGAFSG 430
L G L + P LV G A L P PK A P + P F G
Sbjct: 198 LNGSAALLNSHHAAAPAVSLVNN----GPAALLPLPKPAAPGTVIQTPP--------FVG 245
Query: 431 PGGAPDSAFARRSPDAVASPGAPAPAPAPFRDLASAAATEGGGGDCADAGTAGPAPPPPA 490
P A A SP A +P APA AP P + A G A TA PA PPPA
Sbjct: 246 AAAPP--APAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHP--AGPPTAAPAVPPPA 301
Query: 491 PSPRPGPRPPSPAEEPA------TCGVPEPGAAAGPSPP 523
+ G +PA PA G P PGAAA P
Sbjct: 302 AAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAP 340
Score = 58.2 bits (139), Expect = 2e-08
Identities = 56/183 (30%), Positives = 62/183 (33%), Gaps = 28/183 (15%)
Query: 349 SNAAAAAAAGLDFAPGLPCAPRTLIGKGHFLLYPITQPLGFLVPQAALKGGAGLEPA-PK 407
S AA+AA AP P G LG V + G AG PA P
Sbjct: 31 SQLAASAAHHHHLAPRTPEVRAAAAGA-----------LGNHVVSGSPAGAAGAGPAAPA 79
Query: 408 DAPPAPAVPPAPPAQASFGAFSGPGGAPDSAFARRSPDAVASPGAPAPAPAPFRDLASAA 467
+ P A P P +A PGG SP P PAP A R
Sbjct: 80 EGAPGAAPEPPPAGRAR------PGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRP----- 128
Query: 468 ATEGGGGDCAD-----AGTAGPAPPPPAPSPRPGPRPPSPAEEPATCGVPEPGAAAGPSP 522
EG G CA A AGP P P P+ GP + P P PG GP
Sbjct: 129 PPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGK 188
Query: 523 PEG 525
P G
Sbjct: 189 PAG 191
Score = 53.9 bits (128), Expect = 4e-07
Identities = 76/240 (31%), Positives = 90/240 (37%), Gaps = 39/240 (16%)
Query: 243 SPEPPEPPPPAAKGPGAHASGAAGTAPAPPGEPPAPGTCDPAFYPSQRSGAGPQPRP--G 300
+P PP P P P H +G APA P PPA A +GA P P P G
Sbjct: 269 APPPPPPAPATLARPPGHPAGPPTAAPAVP--PPA------AAQNGGSAGAAPAPAPAAG 320
Query: 301 RPADKDAASCGPGAAVAAVERGA-AGLPK----ASPFSVESLLSDSPPRRKAASNAAAAA 355
PA + GPGAA AA G A PK A+P + ++L + S P AAS
Sbjct: 321 GPAGV-SGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAA-SGPASTAASMVIGPT 378
Query: 356 AAGLDFAPGL--PCAPRTLIGKGHFLLYPITQPLGFLVPQAALKG-GAGLEPAPKDAPPA 412
G +P P AP T G +TQ L P A G A L P A
Sbjct: 379 MQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLS-RTPTATTSGIRATLTPTVL----A 433
Query: 413 PAVPPAPPAQASFGAFSGPGG-------------APDSAFARRSPDAVASPGAP-APAPA 458
P +P P + F P G P A A+ A A P AP PA
Sbjct: 434 PRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPA 493
Score = 37.0 bits (84), Expect = 0.045
Identities = 40/171 (23%), Positives = 61/171 (35%), Gaps = 10/171 (5%)
Query: 241 GLSPEPPEPPPPAAKGPGAHASGAAGTAPAPPGEPPAPGTCD--PAFYPSQRSGAGPQPR 298
G P P PPPA P GAAG P T P+ + PQP
Sbjct: 381 GALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQP- 439
Query: 299 PGRPADKDAASCGPGAAVAAVERG-AAGLPKASPFSVESLLSDSPPRRKAASNAAAAAAA 357
P P + PG + E G +P+ + +++ P A A +A
Sbjct: 440 PQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAP 499
Query: 358 GLDF----APGLPCAPRTLIGKGHFLLYPITQPLGFLVPQAALKGGAGLEP 404
+ APG P R + ++ ++Q + P A L+ G++P
Sbjct: 500 PVQISTVQAPGTPIIARQVTPT--TIIKQVSQAQTTVQPSATLQRSPGVQP 548
>gi|89145413 short stature homeobox 2 isoform a [Homo sapiens]
Length = 331
Score = 92.8 bits (229), Expect = 7e-19
Identities = 46/72 (63%), Positives = 55/72 (76%)
Query: 94 GDPDKESPGCKRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWF 153
G D+ K+RR+RTNFT QL ELE+ F+E+HYPD FMRE L+ RL L E+RVQVWF
Sbjct: 129 GMEDEGQTKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWF 188
Query: 154 QNRRAKWRKKEN 165
QNRRAK RK+EN
Sbjct: 189 QNRRAKCRKQEN 200
>gi|122937484 dorsal root ganglia homeobox [Homo sapiens]
Length = 268
Score = 92.4 bits (228), Expect = 9e-19
Identities = 54/117 (46%), Positives = 71/117 (60%), Gaps = 5/117 (4%)
Query: 93 SGDPDKESPGCKRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVW 152
SGD D K+RR RT FT QLE LE F ++HYPDVF RE LA++++L E+RVQVW
Sbjct: 26 SGDFDDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREELAMKINLTEARVQVW 85
Query: 153 FQNRRAKWRKKEN--TKKGPGRP---AHNSHPTTCSGEPMDPEEIARKELEKMEKKK 204
FQNRRAKWRK E + + PG A + P + P + AR + E +E ++
Sbjct: 86 FQNRRAKWRKTERGASDQEPGAKEPMAEVTPPPVRNINSPPPGDQARSKKEALEAQQ 142
>gi|87044888 short stature homeobox 2 isoform b [Homo sapiens]
Length = 190
Score = 92.0 bits (227), Expect = 1e-18
Identities = 45/69 (65%), Positives = 54/69 (78%)
Query: 97 DKESPGCKRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNR 156
D+ K+RR+RTNFT QL ELE+ F+E+HYPD FMRE L+ RL L E+RVQVWFQNR
Sbjct: 3 DEGQTKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNR 62
Query: 157 RAKWRKKEN 165
RAK RK+EN
Sbjct: 63 RAKCRKQEN 71
>gi|6031203 short stature homeobox isoform SHOXb [Homo sapiens]
Length = 225
Score = 91.7 bits (226), Expect = 2e-18
Identities = 44/62 (70%), Positives = 52/62 (83%)
Query: 104 KRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKK 163
K+RR+RTNFT QL ELE+ F+E+HYPD FMRE L+ RL L E+RVQVWFQNRRAK RK+
Sbjct: 116 KQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQ 175
Query: 164 EN 165
EN
Sbjct: 176 EN 177
>gi|4506943 short stature homeobox isoform SHOXa [Homo sapiens]
Length = 292
Score = 91.7 bits (226), Expect = 2e-18
Identities = 44/62 (70%), Positives = 52/62 (83%)
Query: 104 KRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKK 163
K+RR+RTNFT QL ELE+ F+E+HYPD FMRE L+ RL L E+RVQVWFQNRRAK RK+
Sbjct: 116 KQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQ 175
Query: 164 EN 165
EN
Sbjct: 176 EN 177
>gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Homo
sapiens]
Length = 406
Score = 89.7 bits (221), Expect = 6e-18
Identities = 94/323 (29%), Positives = 117/323 (36%), Gaps = 83/323 (25%)
Query: 101 PGCKRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKW 160
P ++RR RT FT +QL+ELE F+ES YPDV RE LA RL+L E RVQVWFQNRRAKW
Sbjct: 135 PPERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKW 194
Query: 161 RKKENTKKGPGRPAHNSHPTTCSGEPMDPEEIARKELEKMEKKKRKHEKKLLKSQGRHLH 220
++ + + T P+D + G +
Sbjct: 195 KRNQRVL------MLRNTATADLAHPLD-----------------------MFLGGAYYA 225
Query: 221 SPG---GLSLHSAPSSDSDSGGGGLSPEPPEPPPPAAKGPGAHASGAAGTAPAPPGEPPA 277
+P L +H P + P PP PP P P AP PP P
Sbjct: 226 APALDPALCVHLVPQLPRPP----VLPVPPMPPRP----PMVPMPPRPPIAPMPPMAPVP 277
Query: 278 PGTCDPAFYPSQRSGAGPQPRPGRPADKDAASCGPGAAVAAVERGAAGLPKASPFSVESL 337
PG+ P R P P P P +A V G P +P
Sbjct: 278 PGSRMAPVPPGPRMAPVPPWPPMAPVP-------PWPPMAPVPTG----PPMAP------ 320
Query: 338 LSDSPPRRKAASNAAAAAAAGLDFAPGLPCAPRTLIGKGHFLLYPITQPLGFLVPQAALK 397
+ PP + A PG P AP P G P A L
Sbjct: 321 VPPGPPMARVPPGPPMARV-----PPGPPMAP---------------LPPG--PPMAPLP 358
Query: 398 GGAGLEPAPKDAPPAPAVPPAPP 420
G + P PP P + P PP
Sbjct: 359 PGPPMAP----LPPGPPMAPLPP 377
Score = 46.6 bits (109), Expect = 6e-05
Identities = 83/331 (25%), Positives = 98/331 (29%), Gaps = 55/331 (16%)
Query: 229 SAPSSDSD-SGGGGLSPEPPEPPPPAAKGPGAHASGAAGTAPAPPGEPPAPGTCDPAFYP 287
S PS D D GGGG PE + PP K EPP P
Sbjct: 66 SVPSDDQDREGGGGHEPEQQQEEPPLTKPEQQQEEPPLLELKQEQEEPPQTTVEGPQPAE 125
Query: 288 SQRSGAGPQPRPGRPADKDAASC-------------GPGAAVAAVERGAAGLPKASPFSV 334
++ GPQP P R + A V A ER AA L + V
Sbjct: 126 GPQTAEGPQP-PERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARL-NLTEDRV 183
Query: 335 ESLLSDSPPRRKA-------ASNAAAAAAAGLDFAPGLPCAPRTLIGKGHFLLYPITQPL 387
+ + + K + A A A LD G G + P P
Sbjct: 184 QVWFQNRRAKWKRNQRVLMLRNTATADLAHPLDMFLG-----------GAYYAAPALDPA 232
Query: 388 --GFLVPQAALKGGAGLEPAPKDAP-----------PAPAVPPAPPAQASFGAFSGPGGA 434
LVPQ + P P P P P + P PP GP A
Sbjct: 233 LCVHLVPQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMA 292
Query: 435 PDSAFARRSPDAVASPGAPAPAPAPFRDLASAA--ATEGGGGDCADAGTAGPAPPPPAPS 492
P + +P P AP P P + A G A P P P P
Sbjct: 293 PVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLP-PG 351
Query: 493 PRPGPRPPSPAEEPATCGVPEPGAAAGPSPP 523
P P PP P P PG P PP
Sbjct: 352 PPMAPLPPGPPMAPL-----PPGPPMAPLPP 377
>gi|4505619 paired box 7 isoform 1 [Homo sapiens]
Length = 520
Score = 89.0 bits (219), Expect = 1e-17
Identities = 40/60 (66%), Positives = 48/60 (80%)
Query: 104 KRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKK 163
K+RR+RT FT QLEELEKAF +HYPD++ RE LA R L E+RVQVWF NRRA+WRK+
Sbjct: 216 KQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQ 275
>gi|7524359 paired box 7 isoform 2 [Homo sapiens]
Length = 518
Score = 89.0 bits (219), Expect = 1e-17
Identities = 40/60 (66%), Positives = 48/60 (80%)
Query: 104 KRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKK 163
K+RR+RT FT QLEELEKAF +HYPD++ RE LA R L E+RVQVWF NRRA+WRK+
Sbjct: 214 KQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQ 273
>gi|207029223 paired box 7 isoform 3 [Homo sapiens]
Length = 505
Score = 89.0 bits (219), Expect = 1e-17
Identities = 40/60 (66%), Positives = 48/60 (80%)
Query: 104 KRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKK 163
K+RR+RT FT QLEELEKAF +HYPD++ RE LA R L E+RVQVWF NRRA+WRK+
Sbjct: 216 KQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQ 275
>gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]
Length = 483
Score = 88.2 bits (217), Expect = 2e-17
Identities = 43/77 (55%), Positives = 52/77 (67%), Gaps = 4/77 (5%)
Query: 91 SDSGDPDKESPGC----KRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVE 146
SD G P K+RR+RT FT QLEELE+AF +HYPD++ RE LA R L E
Sbjct: 200 SDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTE 259
Query: 147 SRVQVWFQNRRAKWRKK 163
+RVQVWF NRRA+WRK+
Sbjct: 260 ARVQVWFSNRRARWRKQ 276
>gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]
Length = 403
Score = 88.2 bits (217), Expect = 2e-17
Identities = 43/77 (55%), Positives = 52/77 (67%), Gaps = 4/77 (5%)
Query: 91 SDSGDPDKESPGC----KRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVE 146
SD G P K+RR+RT FT QLEELE+AF +HYPD++ RE LA R L E
Sbjct: 201 SDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTE 260
Query: 147 SRVQVWFQNRRAKWRKK 163
+RVQVWF NRRA+WRK+
Sbjct: 261 ARVQVWFSNRRARWRKQ 277
>gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]
Length = 407
Score = 88.2 bits (217), Expect = 2e-17
Identities = 43/77 (55%), Positives = 52/77 (67%), Gaps = 4/77 (5%)
Query: 91 SDSGDPDKESPGC----KRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVE 146
SD G P K+RR+RT FT QLEELE+AF +HYPD++ RE LA R L E
Sbjct: 201 SDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTE 260
Query: 147 SRVQVWFQNRRAKWRKK 163
+RVQVWF NRRA+WRK+
Sbjct: 261 ARVQVWFSNRRARWRKQ 277
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.133 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,706,287
Number of Sequences: 37866
Number of extensions: 2568245
Number of successful extensions: 69040
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1281
Number of HSP's successfully gapped in prelim test: 2400
Number of HSP's that attempted gapping in prelim test: 18511
Number of HSP's gapped (non-prelim): 25075
length of query: 531
length of database: 18,247,518
effective HSP length: 107
effective length of query: 424
effective length of database: 14,195,856
effective search space: 6019042944
effective search space used: 6019042944
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.