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Search of human proteins with 122937227
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|122937227 U2-associated SR140 protein [Homo sapiens]
(1029 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|122937227 U2-associated SR140 protein [Homo sapiens] 2071 0.0
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 91 6e-18
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 87 8e-17
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 87 8e-17
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 85 3e-16
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 85 3e-16
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 84 7e-16
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 83 1e-15
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 82 3e-15
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 81 4e-15
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] 79 3e-14
gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens] 78 4e-14
gi|52426743 cisplatin resistance-associated overexpressed protei... 78 4e-14
gi|19923485 cisplatin resistance-associated overexpressed protei... 78 4e-14
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 78 5e-14
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 77 8e-14
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 76 1e-13
gi|148746195 trichohyalin [Homo sapiens] 74 9e-13
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 74 9e-13
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 74 9e-13
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 74 9e-13
gi|125656165 THO complex 2 [Homo sapiens] 73 1e-12
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 73 1e-12
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 73 1e-12
gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens] 73 1e-12
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 72 3e-12
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 72 3e-12
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 72 3e-12
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 72 4e-12
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 72 4e-12
>gi|122937227 U2-associated SR140 protein [Homo sapiens]
Length = 1029
Score = 2071 bits (5367), Expect = 0.0
Identities = 1029/1029 (100%), Positives = 1029/1029 (100%)
Query: 1 MADKTPGGSQKASSKTRSSDVHSSGSSDAHMDASGPSDSDMPSRTRPKSPRKHNYRNESA 60
MADKTPGGSQKASSKTRSSDVHSSGSSDAHMDASGPSDSDMPSRTRPKSPRKHNYRNESA
Sbjct: 1 MADKTPGGSQKASSKTRSSDVHSSGSSDAHMDASGPSDSDMPSRTRPKSPRKHNYRNESA 60
Query: 61 RESLCDSPHQNLSRPLLENKLKAFSIGKMSTAKRTLSKKEQEELKKKEDEKAAAEIYEEF 120
RESLCDSPHQNLSRPLLENKLKAFSIGKMSTAKRTLSKKEQEELKKKEDEKAAAEIYEEF
Sbjct: 61 RESLCDSPHQNLSRPLLENKLKAFSIGKMSTAKRTLSKKEQEELKKKEDEKAAAEIYEEF 120
Query: 121 LAAFEGSDGNKVKTFVRGGVVNAAKEEHETDEKRGKIYKPSSRFADQKNPPNQSSNERPP 180
LAAFEGSDGNKVKTFVRGGVVNAAKEEHETDEKRGKIYKPSSRFADQKNPPNQSSNERPP
Sbjct: 121 LAAFEGSDGNKVKTFVRGGVVNAAKEEHETDEKRGKIYKPSSRFADQKNPPNQSSNERPP 180
Query: 181 SLLVIETKKPPLKKGEKEKKKSNLELFKEELKQIQEERDERHKTKGRLSRFEPPQSDSDG 240
SLLVIETKKPPLKKGEKEKKKSNLELFKEELKQIQEERDERHKTKGRLSRFEPPQSDSDG
Sbjct: 181 SLLVIETKKPPLKKGEKEKKKSNLELFKEELKQIQEERDERHKTKGRLSRFEPPQSDSDG 240
Query: 241 QRRSMDAPSRRNRSSGVLDDYAPGSHDVGDPSTTNLYLGNINPQMNEEMLCQEFGRFGPL 300
QRRSMDAPSRRNRSSGVLDDYAPGSHDVGDPSTTNLYLGNINPQMNEEMLCQEFGRFGPL
Sbjct: 241 QRRSMDAPSRRNRSSGVLDDYAPGSHDVGDPSTTNLYLGNINPQMNEEMLCQEFGRFGPL 300
Query: 301 ASVKIMWPRTDEERARERNCGFVAFMNRRDAERALKNLNGKMIMSFEMKLGWGKAVPIPP 360
ASVKIMWPRTDEERARERNCGFVAFMNRRDAERALKNLNGKMIMSFEMKLGWGKAVPIPP
Sbjct: 301 ASVKIMWPRTDEERARERNCGFVAFMNRRDAERALKNLNGKMIMSFEMKLGWGKAVPIPP 360
Query: 361 HPIYIPPSMMEHTLPPPPSGLPFNAQPRERLKNPNAPMLPPPKNKEDFEKTLSQAIVKVV 420
HPIYIPPSMMEHTLPPPPSGLPFNAQPRERLKNPNAPMLPPPKNKEDFEKTLSQAIVKVV
Sbjct: 361 HPIYIPPSMMEHTLPPPPSGLPFNAQPRERLKNPNAPMLPPPKNKEDFEKTLSQAIVKVV 420
Query: 421 IPTERNLLALIHRMIEFVVREGPMFEAMIMNREINNPMFRFLFENQTPAHVYYRWKLYSI 480
IPTERNLLALIHRMIEFVVREGPMFEAMIMNREINNPMFRFLFENQTPAHVYYRWKLYSI
Sbjct: 421 IPTERNLLALIHRMIEFVVREGPMFEAMIMNREINNPMFRFLFENQTPAHVYYRWKLYSI 480
Query: 481 LQGDSPTKWRTEDFRMFKNGSFWRPPPLNPYLHGMSEEQETEAFVEEPSKKGALKEEQRD 540
LQGDSPTKWRTEDFRMFKNGSFWRPPPLNPYLHGMSEEQETEAFVEEPSKKGALKEEQRD
Sbjct: 481 LQGDSPTKWRTEDFRMFKNGSFWRPPPLNPYLHGMSEEQETEAFVEEPSKKGALKEEQRD 540
Query: 541 KLEEILRGLTPRKNDIGDAMVFCLNNAEAAEEIVDCITESLSILKTPLPKKIARLYLVSD 600
KLEEILRGLTPRKNDIGDAMVFCLNNAEAAEEIVDCITESLSILKTPLPKKIARLYLVSD
Sbjct: 541 KLEEILRGLTPRKNDIGDAMVFCLNNAEAAEEIVDCITESLSILKTPLPKKIARLYLVSD 600
Query: 601 VLYNSSAKVANASYYRKFFETKLCQIFSDLNATYRTIQGHLQSENFKQRVMTCFRAWEDW 660
VLYNSSAKVANASYYRKFFETKLCQIFSDLNATYRTIQGHLQSENFKQRVMTCFRAWEDW
Sbjct: 601 VLYNSSAKVANASYYRKFFETKLCQIFSDLNATYRTIQGHLQSENFKQRVMTCFRAWEDW 660
Query: 661 AIYPEPFLIKLQNIFLGLVNIIEEKETEDVPDDLDGAPIEEELDGAPLEDVDGIPIDATP 720
AIYPEPFLIKLQNIFLGLVNIIEEKETEDVPDDLDGAPIEEELDGAPLEDVDGIPIDATP
Sbjct: 661 AIYPEPFLIKLQNIFLGLVNIIEEKETEDVPDDLDGAPIEEELDGAPLEDVDGIPIDATP 720
Query: 721 IDDLDGVPIKSLDDDLDGVPLDATEDSKKNEPIFKVAPSKWEAVDESELEAQAVTTSKWE 780
IDDLDGVPIKSLDDDLDGVPLDATEDSKKNEPIFKVAPSKWEAVDESELEAQAVTTSKWE
Sbjct: 721 IDDLDGVPIKSLDDDLDGVPLDATEDSKKNEPIFKVAPSKWEAVDESELEAQAVTTSKWE 780
Query: 781 LFDQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEK 840
LFDQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEK
Sbjct: 781 LFDQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEK 840
Query: 841 RAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKK 900
RAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKK
Sbjct: 841 RAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKK 900
Query: 901 DKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERS 960
DKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERS
Sbjct: 901 DKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERS 960
Query: 961 HKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRS 1020
HKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRS
Sbjct: 961 HKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRS 1020
Query: 1021 HKKSKKNKH 1029
HKKSKKNKH
Sbjct: 1021 HKKSKKNKH 1029
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 90.9 bits (224), Expect = 6e-18
Identities = 74/254 (29%), Positives = 112/254 (44%), Gaps = 28/254 (11%)
Query: 782 FDQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKR 841
FD+ E E+E + + E E E++ + S+S + L + S+ + ++R
Sbjct: 291 FDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRR 350
Query: 842 AKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKD 901
+ RE E E E G+R + DK E+EKE ER RER K+
Sbjct: 351 DRDRERE-------KENERGRRRDRD-----------YDKERGNEREKERERSRERSKEQ 392
Query: 902 KEKLE-SRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERS 960
+ + E K K++KD+ R+ R + + S S R + +S +RS
Sbjct: 393 RSRGEVEEKKHKEDKDD----RRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRS 448
Query: 961 HKESSRSRSSHKDSPRDVSKKAKRSPSGSRT---PKRSRRSRSRSPKKSGKKSRSQSRSP 1017
S S HK+ ++ S K RS S RT K +R S S +KS K+SRS+ RS
Sbjct: 449 RSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSH 508
Query: 1018 HRSHKKSK--KNKH 1029
R H SK +KH
Sbjct: 509 KRDHSDSKDQSDKH 522
Score = 75.9 bits (185), Expect = 2e-13
Identities = 64/221 (28%), Positives = 98/221 (44%), Gaps = 41/221 (18%)
Query: 845 REIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERER-ERDKKDKE 903
R +E + + S +R + +S E + RE E+E ER+R ER+ K++E
Sbjct: 253 RHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKERE 312
Query: 904 KLESRSK----------------------------DKKEKDECTPTRKERKRRHSTSPSP 935
K RS+ D++++D ER RR
Sbjct: 313 KERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDK 372
Query: 936 SRSSSGRRVKSPSPKSERSERS-----ERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSR 990
R + + + S + + +RS E+ HKE R H+D RD K+ K S S SR
Sbjct: 373 ERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDR-RHRDDKRDSKKEKKHSRSRSR 431
Query: 991 TPKRSRRSRSRSPKKSGKKSRSQSR---SPHRSHKKSKKNK 1028
+R RSRSRS + +GK+SRS+S+ S H++ K K NK
Sbjct: 432 --ERKHRSRSRS-RNAGKRSRSRSKEKSSKHKNESKEKSNK 469
Score = 57.4 bits (137), Expect = 7e-08
Identities = 50/208 (24%), Positives = 88/208 (42%), Gaps = 23/208 (11%)
Query: 783 DQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMT--ESKFSKYSEMSEEK 840
D+ E E+E + + + + +++ + + +E KE+ + E + K+ E +++
Sbjct: 351 DRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDR 410
Query: 841 RAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKK 900
R +D+ K+ KK +S + +H R + R K R R ++K
Sbjct: 411 R------------HRDDKRDSKKEKKHSRSRSRERKH-RSRSRSRNAGKR-SRSRSKEKS 456
Query: 901 DKEKLESRSKDKKEKDECTPTR-----KERKRRHSTSPSPSRSSSGRRVKSPSPKSERSE 955
K K ES+ K K + R K +KR HS S SR S R K S K + S+
Sbjct: 457 SKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRS--RSKERSHKRDHSD 514
Query: 956 RSERSHKESSRSRSSHKDSPRDVSKKAK 983
++S K R S + ++ K K
Sbjct: 515 SKDQSDKHDRRRSQSIEQESQEKQHKNK 542
Score = 45.8 bits (107), Expect = 2e-04
Identities = 43/162 (26%), Positives = 71/162 (43%), Gaps = 19/162 (11%)
Query: 883 LQREKEKELERERERDKKD-KEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSG 941
+Q+ +++++ + KKD KE E + + + +P R RR SP SRS S
Sbjct: 225 VQKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRR---SPRRSRSRSH 281
Query: 942 RRVKSPSPKSERS-------ERSERSHKESSRSRSSHKDSPRDV------SKKAKRSPSG 988
R S +R +R ER KE + R + R + S++ RS S
Sbjct: 282 HREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSR 341
Query: 989 SRTPKRSRRSRSRSPKKSGKKSRSQSR--SPHRSHKKSKKNK 1028
SR K RR R R +K ++ R + R R +++ K+ +
Sbjct: 342 SRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERE 383
Score = 40.8 bits (94), Expect = 0.007
Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 1/84 (1%)
Query: 943 RVKSPSPKSERSERSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRS-RRSRSR 1001
R+ P K+ + R K + ++ R V ++ RSP S +P+RS RRSRSR
Sbjct: 220 RIPVPVQKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSR 279
Query: 1002 SPKKSGKKSRSQSRSPHRSHKKSK 1025
S + G S S R R ++ +
Sbjct: 280 SHHREGHGSSSFDRELEREKERQR 303
Score = 35.4 bits (80), Expect = 0.28
Identities = 42/223 (18%), Positives = 87/223 (39%), Gaps = 32/223 (14%)
Query: 42 PSRTRPKSPRKHNYRNESA-RESLCDSPHQNLSRPLLEN---KLKAFSIGKMSTAKRTLS 97
P R+R +S + + + S RE + Q L R E + ++ SI + +R+ S
Sbjct: 273 PRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRS 332
Query: 98 KKEQEELKKKEDEKAAAEIYEEFLAAFEGSDGNKVKTFVRGGVVNAAKEEHETDEKRGKI 157
++ + D K D + K RG + + + D++RG
Sbjct: 333 RERHRSRSRSRDRKGDRR----------DRDREREKENERG-----RRRDRDYDKERGNE 377
Query: 158 YKPSSRFADQKNPPNQSSNERPPSLLVIETKKPPLKKGEKEKKKSNLELFKEELKQIQEE 217
+ + +++ +S E +E KK K ++ + + KE+
Sbjct: 378 REKERERSRERSKEQRSRGE-------VEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRS 430
Query: 218 RDERHKTK------GRLSRFEPPQSDSDGQRRSMDAPSRRNRS 254
R+ +H+++ G+ SR + S + S + ++R+RS
Sbjct: 431 RERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRS 473
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a [Homo
sapiens]
Length = 624
Score = 87.0 bits (214), Expect = 8e-17
Identities = 64/246 (26%), Positives = 114/246 (46%), Gaps = 22/246 (8%)
Query: 787 ESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKE--EMTESKFSKYSEMSEEKRAKL 844
+S ++Q + + S+ ++ +P K+ + E + S+ S +KR
Sbjct: 321 KSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDT 380
Query: 845 REIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDK-KDKE 903
RE +++ +R K+ + + + E R+K +R K K+ ++ERE+D+ KDKE
Sbjct: 381 RE----------KIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKE 430
Query: 904 KLESRSKDKK-EKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHK 962
K R ++K+ EKD KE+ + S+ +R K ++S RS+
Sbjct: 431 KDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKR-----KKDKKSRTPPRSYN 485
Query: 963 ESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRSHK 1022
S RSRSS ++ R S+ + RSP RT K +R SRSP + + + R R H
Sbjct: 486 ASRRSRSSSRERRRRRSRSSSRSP---RTSKTIKRKSSRSPSPRSRNKKDKKREKERDHI 542
Query: 1023 KSKKNK 1028
++ +
Sbjct: 543 SERRER 548
Score = 82.4 bits (202), Expect = 2e-15
Identities = 67/255 (26%), Positives = 119/255 (46%), Gaps = 22/255 (8%)
Query: 785 HEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPI-KEEMTESKFSKYSEMSEEKRAK 843
H S + + +S ++ ++S + + S+ K + T K + + E+ R K
Sbjct: 338 HNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREK 397
Query: 844 LREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDK-KDK 902
RE E + ++ K+ G++ E +D+ +EK++E ERE+E +K +DK
Sbjct: 398 ERERE----------KEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDK 447
Query: 903 EKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHK 962
EK + + K+K+ + + + E++++ S +P RS + R +S S ER R RS
Sbjct: 448 EKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASR-RSRSSSRERRRRRSRSSS 506
Query: 963 ESSRS------RSSHKDSPRDVSKK-AKRSPSGSRTPKRSRRSRSRSPKKSG--KKSRSQ 1013
S R+ +SS SPR +KK KR +R R RS S +KS + + +
Sbjct: 507 RSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEK 566
Query: 1014 SRSPHRSHKKSKKNK 1028
S K+ + NK
Sbjct: 567 LEKNSTSLKEKEHNK 581
Score = 76.6 bits (187), Expect = 1e-13
Identities = 71/288 (24%), Positives = 125/288 (43%), Gaps = 35/288 (12%)
Query: 755 KVAPSKWEAVDESELEAQAVTTSKWELFDQHEESEEEENQNQEEESEDEEDTQSSKSEEH 814
K+ S V E+ QA E+ + E++ + E ES + + +S H
Sbjct: 252 KINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSH 311
Query: 815 -HLYSNPIKEEMTESKFSKYSEMSEE-KRAKLREIELKVMKFQDELESGKRPKKPGQSFQ 872
S + + K S+ S R++ R+ + + K + S R ++ +S
Sbjct: 312 TRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRS 371
Query: 873 EQVEHYRDKLLQ-REKEKELERERERDK---KDKEKLESRSKDK-----KEKDECTPTRK 923
+ +D + +EKE+ E++RE+++ K++EK + R K+K +EKD K
Sbjct: 372 HSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEK 431
Query: 924 ERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKESSRSRSSHKDSPRDVSKKAK 983
+R+R K +R + KE + + KD +++ +K K
Sbjct: 432 DRERERE-------------------KEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRK 472
Query: 984 RSPSGSRTPKR----SRRSRSRSPKKSGKKSRSQSRSPHRSHKKSKKN 1027
+ SRTP R SRRSRS S ++ ++SRS SRSP S +K+
Sbjct: 473 KDKK-SRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKS 519
Score = 74.7 bits (182), Expect = 4e-13
Identities = 56/250 (22%), Positives = 114/250 (45%), Gaps = 16/250 (6%)
Query: 789 EEEENQNQEEESEDEEDTQSS-KSEEHHLYSNPIKEEMTESKFSKYSEMSEEK-RAKLRE 846
E +++++ + +DT+ K +E + KE E + K E + K R K RE
Sbjct: 363 ERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKERE 422
Query: 847 IELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKLE 906
+ + K +D ++ + + +++ E ++K ++++ KE++ +R++DKK +
Sbjct: 423 KDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPR 482
Query: 907 SRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKS----ERSERSERSH- 961
S + ++ + R+ R R S SP S++ + +SPSP+S ++ ER H
Sbjct: 483 SYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHI 542
Query: 962 ---KESSRSRSSHKDS-PRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSP 1017
+E RS S K S RD +K +++ + + + ++ P S K +P
Sbjct: 543 SERRERERSTSMRKSSNDRDGKEKLEKNSTSLK-----EKEHNKEPDSSVSKEVDDKDAP 597
Query: 1018 HRSHKKSKKN 1027
K + N
Sbjct: 598 RTEENKIQHN 607
Score = 57.4 bits (137), Expect = 7e-08
Identities = 50/175 (28%), Positives = 76/175 (43%), Gaps = 13/175 (7%)
Query: 861 GKRPKKPGQSFQEQVE--HYRDKLLQREKEKELERERERDKKDKEKLESRSKDKKEKDEC 918
G RP K S V+ + +E E+ ++R RE +E S E+
Sbjct: 247 GDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNER--- 303
Query: 919 TPTRKERKRRHSTSPSPSRSSS-GRRVKSPSPKSERSERSERSH-KESSRSRSSHKDSPR 976
+ R R H+ S S S S S RR +S S RS RS K+ RS+S HK +
Sbjct: 304 ---KGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSK 360
Query: 977 DVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRSHKKSK---KNK 1028
++ RS S SR ++ R + + ++ +K R + R + +K K KNK
Sbjct: 361 SRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNK 415
Score = 46.6 bits (109), Expect = 1e-04
Identities = 58/242 (23%), Positives = 90/242 (37%), Gaps = 45/242 (18%)
Query: 19 SDVHSSGSSDAHMDASGPSDSDMPSRTRPKSPRKHNYRNESARESL------CDSPHQNL 72
S+ G S +H + S S SR R +S KH R+ + S SPH+
Sbjct: 300 SNERKGGRSRSHTRSKSRSSSKSHSR-RKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKR 358
Query: 73 SRPLLENKLKAFSIGKMSTAKRTLSKKEQEELKKKEDEKAAAEIYEEFLAAFEGSDGNKV 132
S+ K ++ S + KE+E +K+K+ EK
Sbjct: 359 SKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKE-------------------- 398
Query: 133 KTFVRGGVVNAAKEEHETDEKRGKIYKPSSRFADQKNPPNQSSNERPPSLLVIETKKPPL 192
++E E +++RGK + + ER E +K
Sbjct: 399 ---------REREKEREKEKERGKNKDRDKEREKDREKDKEKDRER-------EREKEHE 442
Query: 193 KKGEKEKKKSNLELFKEELKQIQEERDERHKTKGRLSRFEPPQSDSDGQRRSMDAPSRRN 252
K +KEK+K + KE K +E DE+ K K + SR P ++ + RS RR
Sbjct: 443 KDRDKEKEKEQ-DKEKEREKDRSKEIDEKRK-KDKKSRTPPRSYNASRRSRSSSRERRRR 500
Query: 253 RS 254
RS
Sbjct: 501 RS 502
Score = 41.2 bits (95), Expect = 0.005
Identities = 35/119 (29%), Positives = 52/119 (43%), Gaps = 21/119 (17%)
Query: 913 KEKDECTPTRKERKRRHSTSPSPSRSSSGRRV--KSPSPKSERSERSERSHKESSRSRSS 970
KE +E +E + S + P S R +S S +S S +SH RS+S
Sbjct: 273 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSK 332
Query: 971 HKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRSHKKSKKNKH 1029
H+ RS + SR+ ++ RR RS+SP K KSR + +KS+ H
Sbjct: 333 HRS----------RSHNRSRSRQKDRR-RSKSPHKKRSKSRER--------RKSRSRSH 372
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [Homo
sapiens]
Length = 508
Score = 87.0 bits (214), Expect = 8e-17
Identities = 64/246 (26%), Positives = 114/246 (46%), Gaps = 22/246 (8%)
Query: 787 ESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKE--EMTESKFSKYSEMSEEKRAKL 844
+S ++Q + + S+ ++ +P K+ + E + S+ S +KR
Sbjct: 205 KSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDT 264
Query: 845 REIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDK-KDKE 903
RE +++ +R K+ + + + E R+K +R K K+ ++ERE+D+ KDKE
Sbjct: 265 RE----------KIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKE 314
Query: 904 KLESRSKDKK-EKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHK 962
K R ++K+ EKD KE+ + S+ +R K ++S RS+
Sbjct: 315 KDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKR-----KKDKKSRTPPRSYN 369
Query: 963 ESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRSHK 1022
S RSRSS ++ R S+ + RSP RT K +R SRSP + + + R R H
Sbjct: 370 ASRRSRSSSRERRRRRSRSSSRSP---RTSKTIKRKSSRSPSPRSRNKKDKKREKERDHI 426
Query: 1023 KSKKNK 1028
++ +
Sbjct: 427 SERRER 432
Score = 82.4 bits (202), Expect = 2e-15
Identities = 67/255 (26%), Positives = 119/255 (46%), Gaps = 22/255 (8%)
Query: 785 HEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPI-KEEMTESKFSKYSEMSEEKRAK 843
H S + + +S ++ ++S + + S+ K + T K + + E+ R K
Sbjct: 222 HNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREK 281
Query: 844 LREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDK-KDK 902
RE E + ++ K+ G++ E +D+ +EK++E ERE+E +K +DK
Sbjct: 282 ERERE----------KEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDK 331
Query: 903 EKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHK 962
EK + + K+K+ + + + E++++ S +P RS + R +S S ER R RS
Sbjct: 332 EKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASR-RSRSSSRERRRRRSRSSS 390
Query: 963 ESSRS------RSSHKDSPRDVSKK-AKRSPSGSRTPKRSRRSRSRSPKKSG--KKSRSQ 1013
S R+ +SS SPR +KK KR +R R RS S +KS + + +
Sbjct: 391 RSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEK 450
Query: 1014 SRSPHRSHKKSKKNK 1028
S K+ + NK
Sbjct: 451 LEKNSTSLKEKEHNK 465
Score = 76.6 bits (187), Expect = 1e-13
Identities = 71/288 (24%), Positives = 125/288 (43%), Gaps = 35/288 (12%)
Query: 755 KVAPSKWEAVDESELEAQAVTTSKWELFDQHEESEEEENQNQEEESEDEEDTQSSKSEEH 814
K+ S V E+ QA E+ + E++ + E ES + + +S H
Sbjct: 136 KINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSH 195
Query: 815 -HLYSNPIKEEMTESKFSKYSEMSEE-KRAKLREIELKVMKFQDELESGKRPKKPGQSFQ 872
S + + K S+ S R++ R+ + + K + S R ++ +S
Sbjct: 196 TRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRS 255
Query: 873 EQVEHYRDKLLQ-REKEKELERERERDK---KDKEKLESRSKDK-----KEKDECTPTRK 923
+ +D + +EKE+ E++RE+++ K++EK + R K+K +EKD K
Sbjct: 256 HSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEK 315
Query: 924 ERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKESSRSRSSHKDSPRDVSKKAK 983
+R+R K +R + KE + + KD +++ +K K
Sbjct: 316 DRERERE-------------------KEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRK 356
Query: 984 RSPSGSRTPKR----SRRSRSRSPKKSGKKSRSQSRSPHRSHKKSKKN 1027
+ SRTP R SRRSRS S ++ ++SRS SRSP S +K+
Sbjct: 357 KDKK-SRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKS 403
Score = 74.7 bits (182), Expect = 4e-13
Identities = 56/250 (22%), Positives = 114/250 (45%), Gaps = 16/250 (6%)
Query: 789 EEEENQNQEEESEDEEDTQSS-KSEEHHLYSNPIKEEMTESKFSKYSEMSEEK-RAKLRE 846
E +++++ + +DT+ K +E + KE E + K E + K R K RE
Sbjct: 247 ERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKERE 306
Query: 847 IELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKLE 906
+ + K +D ++ + + +++ E ++K ++++ KE++ +R++DKK +
Sbjct: 307 KDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPR 366
Query: 907 SRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKS----ERSERSERSH- 961
S + ++ + R+ R R S SP S++ + +SPSP+S ++ ER H
Sbjct: 367 SYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHI 426
Query: 962 ---KESSRSRSSHKDS-PRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSP 1017
+E RS S K S RD +K +++ + + + ++ P S K +P
Sbjct: 427 SERRERERSTSMRKSSNDRDGKEKLEKNSTSLK-----EKEHNKEPDSSVSKEVDDKDAP 481
Query: 1018 HRSHKKSKKN 1027
K + N
Sbjct: 482 RTEENKIQHN 491
Score = 57.4 bits (137), Expect = 7e-08
Identities = 50/175 (28%), Positives = 76/175 (43%), Gaps = 13/175 (7%)
Query: 861 GKRPKKPGQSFQEQVE--HYRDKLLQREKEKELERERERDKKDKEKLESRSKDKKEKDEC 918
G RP K S V+ + +E E+ ++R RE +E S E+
Sbjct: 131 GDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNER--- 187
Query: 919 TPTRKERKRRHSTSPSPSRSSS-GRRVKSPSPKSERSERSERSH-KESSRSRSSHKDSPR 976
+ R R H+ S S S S S RR +S S RS RS K+ RS+S HK +
Sbjct: 188 ---KGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSK 244
Query: 977 DVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRSHKKSK---KNK 1028
++ RS S SR ++ R + + ++ +K R + R + +K K KNK
Sbjct: 245 SRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNK 299
Score = 46.6 bits (109), Expect = 1e-04
Identities = 58/242 (23%), Positives = 90/242 (37%), Gaps = 45/242 (18%)
Query: 19 SDVHSSGSSDAHMDASGPSDSDMPSRTRPKSPRKHNYRNESARESL------CDSPHQNL 72
S+ G S +H + S S SR R +S KH R+ + S SPH+
Sbjct: 184 SNERKGGRSRSHTRSKSRSSSKSHSR-RKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKR 242
Query: 73 SRPLLENKLKAFSIGKMSTAKRTLSKKEQEELKKKEDEKAAAEIYEEFLAAFEGSDGNKV 132
S+ K ++ S + KE+E +K+K+ EK
Sbjct: 243 SKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKE-------------------- 282
Query: 133 KTFVRGGVVNAAKEEHETDEKRGKIYKPSSRFADQKNPPNQSSNERPPSLLVIETKKPPL 192
++E E +++RGK + + ER E +K
Sbjct: 283 ---------REREKEREKEKERGKNKDRDKEREKDREKDKEKDRER-------EREKEHE 326
Query: 193 KKGEKEKKKSNLELFKEELKQIQEERDERHKTKGRLSRFEPPQSDSDGQRRSMDAPSRRN 252
K +KEK+K + KE K +E DE+ K K + SR P ++ + RS RR
Sbjct: 327 KDRDKEKEKEQ-DKEKEREKDRSKEIDEKRK-KDKKSRTPPRSYNASRRSRSSSRERRRR 384
Query: 253 RS 254
RS
Sbjct: 385 RS 386
Score = 41.2 bits (95), Expect = 0.005
Identities = 35/119 (29%), Positives = 52/119 (43%), Gaps = 21/119 (17%)
Query: 913 KEKDECTPTRKERKRRHSTSPSPSRSSSGRRV--KSPSPKSERSERSERSHKESSRSRSS 970
KE +E +E + S + P S R +S S +S S +SH RS+S
Sbjct: 157 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSK 216
Query: 971 HKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRSHKKSKKNKH 1029
H+ RS + SR+ ++ RR RS+SP K KSR + +KS+ H
Sbjct: 217 HRS----------RSHNRSRSRQKDRR-RSKSPHKKRSKSRER--------RKSRSRSH 256
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 85.1 bits (209), Expect = 3e-16
Identities = 91/366 (24%), Positives = 164/366 (44%), Gaps = 26/366 (7%)
Query: 678 LVNIIEEKETEDVPDDLDGAPIEEELDG---APLEDVDGIPIDATPIDDLDGVPIKSLDD 734
L ++ KE+ ++ P E D A +ED++ + P+ D + SL
Sbjct: 1692 LAALLSPKESSGGEKEVPPPPKETLPDSGFSANIEDINEADL-VRPLLPKDMERLTSLRA 1750
Query: 735 DLDGVPLDATEDSKKNEPIFKVAPSKWEAVDESELEAQAVTTSKWELF----DQHEESEE 790
++G PL A++ + V S E ES E + +E+F D HE+S++
Sbjct: 1751 GIEG-PLLASDVGRDRSAASPVVSSMPERASESSSEEK----DDYEIFVKVKDTHEKSKK 1805
Query: 791 EENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLREIELK 850
+N+++ E+ + + + S+S+ + ++ +ES+ S+ + S + ++ + +
Sbjct: 1806 NKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESR-SRARKRSSKSKSHRSQTRSR 1864
Query: 851 VMKFQDELESGKRPKKPGQ-SFQEQVEHYRDKLLQREKEKELERERERDKKDKEKLESRS 909
+ S R K G+ S ++ K + +E++ +R RD + + SR+
Sbjct: 1865 SRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRT 1924
Query: 910 KDKKEKDECTPTRKERKR----RHSTSPSPSRSSS--GRRVKSPSPKSERSERSERSHKE 963
++ + TP+R+ R R R S S SPSR S RR ++PS +S R R+
Sbjct: 1925 PSRRSRSH-TPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSR 1983
Query: 964 SSR--SRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKS--RSQSRSPHR 1019
SR SR S S R S+ R S S +P R RRSR+ ++ + R +SRS R
Sbjct: 1984 RSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSER 2043
Query: 1020 SHKKSK 1025
+
Sbjct: 2044 GRSPKR 2049
Score = 68.9 bits (167), Expect = 2e-11
Identities = 63/216 (29%), Positives = 101/216 (46%), Gaps = 16/216 (7%)
Query: 818 SNPIKEEMTESKFSKYSEMSEEKRAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEH 877
++P+ M E + SE S E++ EI +KV +D E K+ K + +E+
Sbjct: 1768 ASPVVSSMPE----RASESSSEEKDDY-EIFVKV---KDTHEKSKKNKNRDKGEKEKKRD 1819
Query: 878 YRDKLLQREKEKELERERERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSR 937
L R K + + R + + + +R + K K + TR + R S SR
Sbjct: 1820 --SSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSR 1877
Query: 938 SSSGRRVKSPSPKSERSERSERSHKESSRSRSSHKDSPRDVSKKAKRSP---SGSRTPKR 994
S S R K +RS + +E R RSS +D+ + V ++ R+P S S TP R
Sbjct: 1878 SKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARS-RTPSRRSRSHTPSR 1936
Query: 995 SRRSRSRSPKKSGKKSRS-QSRSP-HRSHKKSKKNK 1028
RRSRS ++S S S +SR+P RS S++++
Sbjct: 1937 RRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSR 1972
Score = 50.8 bits (120), Expect = 6e-06
Identities = 42/140 (30%), Positives = 62/140 (44%), Gaps = 19/140 (13%)
Query: 890 ELERERERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSP 949
E E ++KD ++ + KD EK K+ K R R SS ++S S
Sbjct: 1777 ERASESSSEEKDDYEIFVKVKDTHEKS------KKNKNRDKGEKEKKRDSS---LRSRSK 1827
Query: 950 KSERSERSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKK 1009
+S+ SE R SRSR+ + S K+ RS + SR+ R RR SRS +
Sbjct: 1828 RSKSSEHKSRKRTSESRSRARKRSS----KSKSHRSQTRSRSRSRRRRRSSRS------R 1877
Query: 1010 SRSQSRSPHRSHKKSKKNKH 1029
S+S+ R K+ + KH
Sbjct: 1878 SKSRGRRSVSKEKRKRSPKH 1897
Score = 31.2 bits (69), Expect = 5.3
Identities = 32/162 (19%), Positives = 67/162 (41%), Gaps = 6/162 (3%)
Query: 796 QEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLREIELKVMKFQ 855
Q+E S + Q + + N + ++ E+ ++ L + ++++
Sbjct: 21 QQELSSGRNEGQLNGETNTPIEGNQAGDAAASARSLPNEEIVQKIEEVLSGVLDTELRYK 80
Query: 856 DELESGKRPKKPGQSFQ----EQVEHYRDKLLQREKEKELERERERDKKDKEKLE-SRSK 910
+L+ G R K S Q +++ + K ++ K K+ ++++E++KK K + E S SK
Sbjct: 81 PDLKEGSR-KSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESESK 139
Query: 911 DKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSE 952
K D + + + PS R PS +E
Sbjct: 140 TKSHDDGNIDLESDSFLKFDSEPSAVALELPTRAFGPSETNE 181
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 85.1 bits (209), Expect = 3e-16
Identities = 91/366 (24%), Positives = 164/366 (44%), Gaps = 26/366 (7%)
Query: 678 LVNIIEEKETEDVPDDLDGAPIEEELDG---APLEDVDGIPIDATPIDDLDGVPIKSLDD 734
L ++ KE+ ++ P E D A +ED++ + P+ D + SL
Sbjct: 1692 LAALLSPKESSGGEKEVPPPPKETLPDSGFSANIEDINEADL-VRPLLPKDMERLTSLRA 1750
Query: 735 DLDGVPLDATEDSKKNEPIFKVAPSKWEAVDESELEAQAVTTSKWELF----DQHEESEE 790
++G PL A++ + V S E ES E + +E+F D HE+S++
Sbjct: 1751 GIEG-PLLASDVGRDRSAASPVVSSMPERASESSSEEK----DDYEIFVKVKDTHEKSKK 1805
Query: 791 EENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLREIELK 850
+N+++ E+ + + + S+S+ + ++ +ES+ S+ + S + ++ + +
Sbjct: 1806 NKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESR-SRARKRSSKSKSHRSQTRSR 1864
Query: 851 VMKFQDELESGKRPKKPGQ-SFQEQVEHYRDKLLQREKEKELERERERDKKDKEKLESRS 909
+ S R K G+ S ++ K + +E++ +R RD + + SR+
Sbjct: 1865 SRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRT 1924
Query: 910 KDKKEKDECTPTRKERKR----RHSTSPSPSRSSS--GRRVKSPSPKSERSERSERSHKE 963
++ + TP+R+ R R R S S SPSR S RR ++PS +S R R+
Sbjct: 1925 PSRRSRSH-TPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSR 1983
Query: 964 SSR--SRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKS--RSQSRSPHR 1019
SR SR S S R S+ R S S +P R RRSR+ ++ + R +SRS R
Sbjct: 1984 RSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSER 2043
Query: 1020 SHKKSK 1025
+
Sbjct: 2044 GRSPKR 2049
Score = 68.9 bits (167), Expect = 2e-11
Identities = 63/216 (29%), Positives = 101/216 (46%), Gaps = 16/216 (7%)
Query: 818 SNPIKEEMTESKFSKYSEMSEEKRAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEH 877
++P+ M E + SE S E++ EI +KV +D E K+ K + +E+
Sbjct: 1768 ASPVVSSMPE----RASESSSEEKDDY-EIFVKV---KDTHEKSKKNKNRDKGEKEKKRD 1819
Query: 878 YRDKLLQREKEKELERERERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSR 937
L R K + + R + + + +R + K K + TR + R S SR
Sbjct: 1820 --SSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSR 1877
Query: 938 SSSGRRVKSPSPKSERSERSERSHKESSRSRSSHKDSPRDVSKKAKRSP---SGSRTPKR 994
S S R K +RS + +E R RSS +D+ + V ++ R+P S S TP R
Sbjct: 1878 SKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARS-RTPSRRSRSHTPSR 1936
Query: 995 SRRSRSRSPKKSGKKSRS-QSRSP-HRSHKKSKKNK 1028
RRSRS ++S S S +SR+P RS S++++
Sbjct: 1937 RRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSR 1972
Score = 50.8 bits (120), Expect = 6e-06
Identities = 42/140 (30%), Positives = 62/140 (44%), Gaps = 19/140 (13%)
Query: 890 ELERERERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSP 949
E E ++KD ++ + KD EK K+ K R R SS ++S S
Sbjct: 1777 ERASESSSEEKDDYEIFVKVKDTHEKS------KKNKNRDKGEKEKKRDSS---LRSRSK 1827
Query: 950 KSERSERSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKK 1009
+S+ SE R SRSR+ + S K+ RS + SR+ R RR SRS +
Sbjct: 1828 RSKSSEHKSRKRTSESRSRARKRSS----KSKSHRSQTRSRSRSRRRRRSSRS------R 1877
Query: 1010 SRSQSRSPHRSHKKSKKNKH 1029
S+S+ R K+ + KH
Sbjct: 1878 SKSRGRRSVSKEKRKRSPKH 1897
Score = 31.2 bits (69), Expect = 5.3
Identities = 32/162 (19%), Positives = 67/162 (41%), Gaps = 6/162 (3%)
Query: 796 QEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLREIELKVMKFQ 855
Q+E S + Q + + N + ++ E+ ++ L + ++++
Sbjct: 21 QQELSSGRNEGQLNGETNTPIEGNQAGDAAASARSLPNEEIVQKIEEVLSGVLDTELRYK 80
Query: 856 DELESGKRPKKPGQSFQ----EQVEHYRDKLLQREKEKELERERERDKKDKEKLE-SRSK 910
+L+ G R K S Q +++ + K ++ K K+ ++++E++KK K + E S SK
Sbjct: 81 PDLKEGSR-KSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESESK 139
Query: 911 DKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSE 952
K D + + + PS R PS +E
Sbjct: 140 TKSHDDGNIDLESDSFLKFDSEPSAVALELPTRAFGPSETNE 181
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 84.0 bits (206), Expect = 7e-16
Identities = 65/242 (26%), Positives = 105/242 (43%), Gaps = 19/242 (7%)
Query: 788 SEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLREI 847
S+ ++ ++ ++ D S+S H + + E + + + R + +E
Sbjct: 267 SKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEE-EKRGSVSRGRSQEK 325
Query: 848 ELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKLES 907
L+ + + + G R + +S +DK R++ +E R R R + E+
Sbjct: 326 SLRQSRSRSRSKGGSRSRSRSRSKS------KDKRKGRKRSREESRSRSRSRSKSERSRK 379
Query: 908 RSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSH-----K 962
R + K + +K+ S S SPSRS S R + S S+R R E + +
Sbjct: 380 RGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQE 439
Query: 963 ESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRSHK 1022
SRSRS+ K P S+ RS S S+T RSRS +S SRS SRS RSH
Sbjct: 440 TRSRSRSNSKSKPNLPSESRSRSKSASKT-------RSRSKSRSRSASRSPSRSRSRSHS 492
Query: 1023 KS 1024
+S
Sbjct: 493 RS 494
Score = 70.5 bits (171), Expect = 8e-12
Identities = 64/234 (27%), Positives = 97/234 (41%), Gaps = 23/234 (9%)
Query: 809 SKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLREIELKVMKFQDELESGK-RPKKP 867
S+S +S + SK S +S+ R+ R + Q S K + + P
Sbjct: 192 SRSRSRSRHSRKSRSRSGSSK-SSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSP 250
Query: 868 GQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKLESRSKDK---KEKDECTPTRKE 924
+ H K + K++ E+ + D K K S S+ K K + R E
Sbjct: 251 SKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVE 310
Query: 925 RKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKESSRSRSSHKDSPRDVSKKAKR 984
++R S S S+ S R+ +S S RS+ + SRSRS KD + + +
Sbjct: 311 EEKRGSVSRGRSQEKSLRQSRSRS-------RSKGGSRSRSRSRSKSKDKRKGRKRSREE 363
Query: 985 SPSGSRTPKRSRRSRSRSPKKSGK-----------KSRSQSRSPHRSHKKSKKN 1027
S S SR+ +S RSR R K+ K RSQSRSP RS K +++
Sbjct: 364 SRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREH 417
Score = 68.2 bits (165), Expect = 4e-11
Identities = 70/256 (27%), Positives = 106/256 (41%), Gaps = 30/256 (11%)
Query: 785 HEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKL 844
H +S S+ +QS + +P KE+ S S+ K
Sbjct: 215 HSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAE 274
Query: 845 REIE----LKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQR--EKEKELERERERD 898
+I+ + K + + K +S + +VE + + R +EK L + R R
Sbjct: 275 EKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRS 334
Query: 899 K-KDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERS 957
+ K + SRS+ K KD+ RK RKR S S SRS S KSERS +
Sbjct: 335 RSKGGSRSRSRSRSKS-KDK----RKGRKRSREESRSRSRSRS---------KSERSRK- 379
Query: 958 ERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGK------KSR 1011
R K S++ SS K D + RSPS S K ++S S ++ G+ +
Sbjct: 380 -RGSKRDSKAGSSKKKKKEDTDRSQSRSPSRS-VSKEREHAKSESSQREGRGESENAGTN 437
Query: 1012 SQSRSPHRSHKKSKKN 1027
++RS RS+ KSK N
Sbjct: 438 QETRSRSRSNSKSKPN 453
Score = 66.6 bits (161), Expect = 1e-10
Identities = 75/278 (26%), Positives = 114/278 (41%), Gaps = 49/278 (17%)
Query: 792 ENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRA--KLREIEL 849
EN + +D +D E + ++ ++ +F YS+M KRA KL E+
Sbjct: 109 ENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDM---KRALEKLDGTEV 165
Query: 850 KVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERE----------RERDK 899
K + L K + +S+ H R + R K R R R +
Sbjct: 166 NGRKIR--LVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSR 223
Query: 900 -------KDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGR---------- 942
K + + +SRS+ KKEK K R R HS S S+S
Sbjct: 224 SGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNV 283
Query: 943 -RVKSPSPKSERSERSERSHKESSR---------SRSSHKDSPRDVSKKAKRSPSGSRTP 992
+ KS SP +S+ RS + R SR ++ S+ RS GSR+
Sbjct: 284 GKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSR 343
Query: 993 KRSRRSRSRSPKKSGKKSR--SQSRSPHRSHKKSKKNK 1028
RSR S+S+ +K K+SR S+SRS RS KS++++
Sbjct: 344 SRSR-SKSKDKRKGRKRSREESRSRS--RSRSKSERSR 378
Score = 53.9 bits (128), Expect = 8e-07
Identities = 57/232 (24%), Positives = 97/232 (41%), Gaps = 43/232 (18%)
Query: 784 QHEESEEEENQNQEEESEDEE--DTQSSKSEEHHLYSNPIKEEM---TESKFSKYSEMSE 838
+H+ + +++QE E+E+ +S+E L + + + S+ S+ +
Sbjct: 293 RHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKD 352
Query: 839 EKRAKLREIELKVMKFQDELES-------GKRPKKPGQSFQEQVEHYRDKLLQREKEKEL 891
+++ + R E + + +S KR K G S +++ E D+ R + +
Sbjct: 353 KRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKED-TDRSQSRSPSRSV 411
Query: 892 ERERERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKS 951
+ERE K + + E R E + ++ R R S S S P+ S
Sbjct: 412 SKEREHAKSESSQREGRG----ESENAGTNQETRSRSRSNSKS-----------KPNLPS 456
Query: 952 ERSERSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSR-RSRSRS 1002
E RS+ + K SRS+S RS S SR+P RSR RS SRS
Sbjct: 457 ESRSRSKSASKTRSRSKS--------------RSRSASRSPSRSRSRSHSRS 494
Score = 37.4 bits (85), Expect = 0.073
Identities = 43/236 (18%), Positives = 90/236 (38%), Gaps = 5/236 (2%)
Query: 12 ASSKTRSSDVHSSGSSDAHMDASGPSDSDMPSRTRPKSPRKHNYRNESARESLCDSPHQN 71
++ K+RS + + D G S PSR + KS + + E S +
Sbjct: 261 SAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRG 320
Query: 72 LSRPLLENKLKAFSIGKMSTAKRTLSKKEQEELKKKEDEKAAAEIYEEFLAAFEGSDGNK 131
S+ + ++ S K + R+ S+ + ++ K++ K + E + S+ ++
Sbjct: 321 RSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKD--KRKGRKRSREESRSRSRSRSKSERSR 378
Query: 132 VKTFVRGGVVNAAKEEHETDEKRGKIYKPSSRFADQKNPPNQSSNERP---PSLLVIETK 188
+ R ++K++ + D R + PS + ++ S++R S +
Sbjct: 379 KRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQ 438
Query: 189 KPPLKKGEKEKKKSNLELFKEELKQIQEERDERHKTKGRLSRFEPPQSDSDGQRRS 244
+ + K K NL + + R K++ R + P +S S RS
Sbjct: 439 ETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
Score = 34.3 bits (77), Expect = 0.62
Identities = 44/256 (17%), Positives = 101/256 (39%), Gaps = 21/256 (8%)
Query: 7 GGSQKASSKTRSSDVHSSGSSDAHMDASGPSDSDMPSRTRPKSPRKHNYRNESARESLCD 66
G S+ + SK+RS SGS S + + +SP K R+ S
Sbjct: 209 GSSKSSHSKSRSRS--RSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSR 266
Query: 67 SPHQNLSRPLLEN-----KLKAFSIGKMSTAKRTLSKKEQEELKKKEDEKAAAEIYEEFL 121
S ++ + ++N K K+ S + + ++ S+ ++ +++++ + +E
Sbjct: 267 SKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQE-- 324
Query: 122 AAFEGSDGNKVKTFVRGGVVNAAKEEHETDEKR--GKIYKPSSRFADQKNPPNQSSNERP 179
+ ++ ++ +GG + ++ ++ +KR K + SR + ++ S +R
Sbjct: 325 ---KSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKR- 380
Query: 180 PSLLVIETKKPPLKKGEKEKKKSNLELFKEELKQIQEERDERHKTKGRLSRFEPPQSDSD 239
+K+ K+KKK + + + ++ H R +S++
Sbjct: 381 ------GSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENA 434
Query: 240 GQRRSMDAPSRRNRSS 255
G + + SR N S
Sbjct: 435 GTNQETRSRSRSNSKS 450
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 83.2 bits (204), Expect = 1e-15
Identities = 56/251 (22%), Positives = 109/251 (43%), Gaps = 10/251 (3%)
Query: 783 DQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRA 842
++ +++ E + E + E + + ++ E KE TE + S+ E +R
Sbjct: 158 ERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERE 217
Query: 843 KLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDK 902
E E K + D +R + + Q + E ++ +R+KE+E ER+R+RD+ +
Sbjct: 218 TETETERK--RQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRR 275
Query: 903 EKLESRSKDKK-----EKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSER-SER 956
+K R D+K E+D T ++ER+R +R R + + +R +ER
Sbjct: 276 QKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETER 335
Query: 957 SERSHKESSRSRSSHKDSPRD--VSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQS 1014
+E R R + D R+ ++ +R R +R R +S ++ ++ R +
Sbjct: 336 DREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRD 395
Query: 1015 RSPHRSHKKSK 1025
R R + K
Sbjct: 396 RQKERERQTEK 406
Score = 77.0 bits (188), Expect = 8e-14
Identities = 62/271 (22%), Positives = 118/271 (43%), Gaps = 25/271 (9%)
Query: 783 DQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSE---MSEE 839
D E + ++E + + E+ + E +T + + ++ E + + E ++
Sbjct: 52 DDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDR 111
Query: 840 KRAKLREIELKVMKFQD-ELE-SGKRPKKPGQSFQEQVEHYRDKLLQREKEKELER---- 893
+R + RE E K ++ E E G+R + Q + E RD +RE++ + ER
Sbjct: 112 ERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQT 171
Query: 894 ------ERERDKKDKEKLE---SRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRV 944
ERER+K +E+ E R K+ K +D + +ER+R T R R
Sbjct: 172 ERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRE 231
Query: 945 KSPSPKSER-----SERSERSHKESSR--SRSSHKDSPRDVSKKAKRSPSGSRTPKRSRR 997
+ K+ER +ER S +E+ R R +D RD ++ K + ++ R
Sbjct: 232 RDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRT 291
Query: 998 SRSRSPKKSGKKSRSQSRSPHRSHKKSKKNK 1028
R R ++ ++ R + R R+ K+ ++ +
Sbjct: 292 ERDRETERKRERQRERERERERNRKRERERE 322
Score = 76.3 bits (186), Expect = 1e-13
Identities = 64/268 (23%), Positives = 117/268 (43%), Gaps = 17/268 (6%)
Query: 765 DESELEAQAVTTSKWELFDQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEE 824
+ E E Q +K E D+H E E + +E E+E E Q+ + + + +E+
Sbjct: 187 ERRERERQREKENKTE--DRHSERGRERERERETETETERKRQTDRERDRQRKTEREREK 244
Query: 825 MTESKFSKYSEMSEEKRAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQ 884
E + + SE E +R K RE E + +D + +R ++ + Q + E R+
Sbjct: 245 QAERE--RASER-ETERDKERERERDRDRDRDRRQK-ERERQTDRKRQRRTERDRET--- 297
Query: 885 REKEKELERERERDKKDKEKLESRSKDKKEKDECTPT------RKERKRRHSTSPSPSRS 938
E+++E +RERER+++ K E + ++E++ T +ERKR+ T R+
Sbjct: 298 -ERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERN 356
Query: 939 SSGRRVKSPSPKSERSERSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRS 998
R + ER ER + + +D RD K+ +R R +R
Sbjct: 357 RQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQR-ETE 415
Query: 999 RSRSPKKSGKKSRSQSRSPHRSHKKSKK 1026
+ R +K + R + R R +K ++
Sbjct: 416 KQREREKDRESERGRERGREREKQKGRE 443
Score = 75.5 bits (184), Expect = 2e-13
Identities = 55/262 (20%), Positives = 111/262 (42%), Gaps = 29/262 (11%)
Query: 766 ESELEAQAVTTSKWELF---DQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIK 822
E E E + T K + D+ ++E E + E E E +T+ K E + +
Sbjct: 213 ERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDR 272
Query: 823 EEMTESKFSKYSEMSEEKRAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKL 882
+ + + + + + + RE E K + ++ +R +K + + + E R +
Sbjct: 273 DRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRE 332
Query: 883 LQREKEKELERERERD-------------------------KKDKEKLESRSKDKKEKDE 917
+R++EKE ER+R+R ++++++ +R ++++E+D
Sbjct: 333 TERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDR 392
Query: 918 CTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERS-ERSERSHKESSRSRSSHKDSPR 976
+KER+R+ R + +R + +SER ER K+ R R + + R
Sbjct: 393 DRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDR 452
Query: 977 DVSKKAKRSPSGSRTPKRSRRS 998
++ KRS P R+ RS
Sbjct: 453 QAGRQRKRSTLYVNPPPRTARS 474
Score = 75.1 bits (183), Expect = 3e-13
Identities = 54/259 (20%), Positives = 118/259 (45%), Gaps = 15/259 (5%)
Query: 783 DQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRA 842
D+H E + + + +E +++ E D Q K E E + ++ + +R
Sbjct: 92 DRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTD-GQRERE 150
Query: 843 KLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHY---RDKLLQREKEKELE------- 892
+ R+ E K + Q + E ++ ++ Q +E+ ++ R++ QREKE + E
Sbjct: 151 RQRDAE-KERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERG 209
Query: 893 RERERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSS--SGRRVKSPSPK 950
RERER+++ + + E + + +E+D T +ER+++ + R + R +
Sbjct: 210 RERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRD 269
Query: 951 SERSERSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSR-RSRSRSPKKSGKK 1009
+R R + +++ R R + R+ +K +R R +R+R R R R ++ ++
Sbjct: 270 RDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERER 329
Query: 1010 SRSQSRSPHRSHKKSKKNK 1028
R R + ++ +K +
Sbjct: 330 QRETERDREKERERKRKRQ 348
Score = 74.3 bits (181), Expect = 5e-13
Identities = 55/266 (20%), Positives = 120/266 (45%), Gaps = 21/266 (7%)
Query: 783 DQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMS---EE 839
++ E E E ++++ + + E + Q +E ++ ++ TE K E +E
Sbjct: 128 ERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQE 187
Query: 840 KRAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERER---- 895
+R + R+ E K K +D R ++ + + + E R +R+++++ ERER
Sbjct: 188 RRERERQRE-KENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQA 246
Query: 896 ----------ERDK-KDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRV 944
ERDK +++E+ R +D+++K+ T ++R+RR R +R
Sbjct: 247 ERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRE 306
Query: 945 KS-PSPKSERSERSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKR-SRRSRSRS 1002
+ ++ + ER +E R R + +D ++ +K KR R R + R R
Sbjct: 307 RERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQ 366
Query: 1003 PKKSGKKSRSQSRSPHRSHKKSKKNK 1028
++ ++ R + R R ++ ++++
Sbjct: 367 AERERERERERDRQSAREREERERDR 392
Score = 70.9 bits (172), Expect = 6e-12
Identities = 60/257 (23%), Positives = 111/257 (43%), Gaps = 17/257 (6%)
Query: 783 DQHEESEEEENQNQEEESEDE----EDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSE 838
D+ E E + +E E+E E D Q+ E + KE ++ + + +E
Sbjct: 114 DRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQ-TE 172
Query: 839 EKRAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELER----E 894
R K RE E Q+ E ++ +K ++ E R++ +RE E E ER +
Sbjct: 173 RNRQKERERE---KNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTD 229
Query: 895 RERDKKDKEKLESRSKDKKEK--DECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSE 952
RERD++ K + E + ++E+ + T KER+R R R ++ +
Sbjct: 230 RERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQR 289
Query: 953 RSERSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRS-RSRSPKKSGKKSR 1011
R+ER + E R R ++ R+ ++K +R R +R R + R R ++ K+ R
Sbjct: 290 RTERDRET--ERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKR 347
Query: 1012 SQSRSPHRSHKKSKKNK 1028
R+ + ++ +
Sbjct: 348 QTEMDRERNRQTGREGR 364
Score = 57.4 bits (137), Expect = 7e-08
Identities = 60/248 (24%), Positives = 106/248 (42%), Gaps = 44/248 (17%)
Query: 784 QHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEK--- 840
+ E E E N+ +E E E E + + + E +E+ E K + +EM E+
Sbjct: 305 RERERERERNRKRERERERERERERQRETERD------REKERERKRKRQTEMDRERNRQ 358
Query: 841 ------------RAKLREIELKVMKFQDELESGK---RPKKPGQSFQEQVEHYRDKLLQR 885
R + RE + + + ++E E + R K+ + ++ + R+ QR
Sbjct: 359 TGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQR 418
Query: 886 EKEKELERERERDK-KDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRV 944
E+EK+ E ER R++ +++EK + R +D++ + + R+ ++ +P P + SG
Sbjct: 419 EREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQ 478
Query: 945 KSPSPKSERSERSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSR---RSRSR 1001
P+ R R R K SP D + R P G R K SR R R
Sbjct: 479 SDPN----RPTRGIR-----------WKSSPEDPKAASTRFPWG-RPAKASRGRVAGRRR 522
Query: 1002 SPKKSGKK 1009
+ G+K
Sbjct: 523 WEPRLGEK 530
Score = 55.5 bits (132), Expect = 3e-07
Identities = 38/173 (21%), Positives = 74/173 (42%), Gaps = 7/173 (4%)
Query: 859 ESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKLESRSKDKKEKDEC 918
+ R + GQ+ ++ R++ Q+E+E+ E+ + + D+++ R KD+ K +
Sbjct: 34 QESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRD- 92
Query: 919 TPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKESSRSRSSHKDSPRDV 978
++R R R +R K + + ER +ER E R R D R+
Sbjct: 93 RHRERQRDREKERERQTDRERDRQREKERNRQKERERETER---EGERGRDRQTDGQRER 149
Query: 979 SKKAKRSPSGSRTPKRSRR---SRSRSPKKSGKKSRSQSRSPHRSHKKSKKNK 1028
++ R R R+ R+R ++ +K+R + R R +K K +
Sbjct: 150 ERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTE 202
Score = 40.0 bits (92), Expect = 0.011
Identities = 29/138 (21%), Positives = 53/138 (38%), Gaps = 19/138 (13%)
Query: 893 RERERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSE 952
R ++ + L KD D +KER+R RR K + +
Sbjct: 30 RPGSQESPRRRGLGQAHKDADGDDRERNRQKERER--------------RREKRQTERET 75
Query: 953 RSERSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSR-----RSRSRSPKKSG 1007
+R R K+ R R H++ RD K+ +R R +R + + R R ++ G
Sbjct: 76 DRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREG 135
Query: 1008 KKSRSQSRSPHRSHKKSK 1025
++ R + R ++ +
Sbjct: 136 ERGRDRQTDGQRERERQR 153
Score = 32.0 bits (71), Expect = 3.1
Identities = 47/234 (20%), Positives = 89/234 (38%), Gaps = 11/234 (4%)
Query: 25 GSSDAHMDASGPSD--SDMPSRTRPKSPRKHNYRNESARESLCDSPHQNLSRPLLENKLK 82
G AH DA G + R R + R+ + RE + E +
Sbjct: 41 GLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRD 100
Query: 83 AFSIGKMSTAKRTLSKKEQEELKKKEDEKAAAEIYEEFLAAFEGSDGNKVKTFVRGGVVN 142
+ T + ++E+E ++KE E+ E +DG + + R +
Sbjct: 101 REKERERQTDRERDRQREKERNRQKERERETEREGER--GRDRQTDGQRERERQR----D 154
Query: 143 AAKE-EHETDEKRGKIYKPSSRFADQKNPPNQSSNERPPSL-LVIETKKPPLKKGEKEKK 200
A KE E +TD +R + + + + ++ Q ER +T+ ++G + ++
Sbjct: 155 AEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERER 214
Query: 201 KSNLELFKEELKQIQEERDERHKT-KGRLSRFEPPQSDSDGQRRSMDAPSRRNR 253
+ E E +Q ERD + KT + R + E ++ R + R+R
Sbjct: 215 ERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDR 268
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 82.0 bits (201), Expect = 3e-15
Identities = 80/308 (25%), Positives = 141/308 (45%), Gaps = 24/308 (7%)
Query: 731 SLDDDLDGVPLDATEDSKKNEPIFKVAPSKWEAVDESELEAQAVTTSKWELFDQHEESEE 790
SL + L +P +T K+E KV V++SE E V E E +EE
Sbjct: 421 SLPEGLPKIPSVSTHIKVKSEEKIKV-------VEKSEKETVIVEEQTEETQVTEEVTEE 473
Query: 791 EENQNQEEESEDEEDTQSSKSE--EHHLYSNPIKEEMTESKFSKYSEMSEEKR-AKLREI 847
EE + +EEE ++EE + ++E E S P +E + K +K E K A+ +
Sbjct: 474 EEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSP 533
Query: 848 ELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEK---ELERERERDKKDKEK 904
E + K E++S ++ K P + +E K ++E+ K E++ + KE+
Sbjct: 534 EKEEAKSPAEVKSPEKAKSPAK--EEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEE 591
Query: 905 LESRSKDKKEKDECTPTRKERKR-RHSTSPSPSRSSSGRRVKSP----SPKSERSERSER 959
+S ++ K + +P ++E K + SP + S VKSP SP E ++ E+
Sbjct: 592 AKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEK 651
Query: 960 SHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRS---RSRSPKKSGKKSRSQSRS 1016
+ S + + V +AK SP +++P ++ +++SP K KS +++S
Sbjct: 652 AKSPEKEEAKSPEKAKSPVKAEAK-SPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKS 710
Query: 1017 PHRSHKKS 1024
P + KS
Sbjct: 711 PVKEEAKS 718
Score = 60.8 bits (146), Expect = 6e-09
Identities = 75/357 (21%), Positives = 147/357 (41%), Gaps = 28/357 (7%)
Query: 683 EEKETEDVPDDLDGAPIEEELDGAPLEDVDGIPIDATPIDDLDGVPIKSLDDDLDGVPLD 742
EEKE ++ + EEE +G E +A + P+K
Sbjct: 474 EEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSP 533
Query: 743 ATEDSKKNEPIFKVAPSKWEAVDESELEAQAVTTSKWELFDQHE-ESEEEENQNQEEESE 801
E++K + +K A +E++ +A + K E E +S E+ +EE++
Sbjct: 534 EKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAK 593
Query: 802 DEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKR-AKLREIELKVMKFQDELES 860
+ +S + + +P+KEE +K E K A+++ E ++E +S
Sbjct: 594 SPAEAKSPEKAK-----SPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKS 648
Query: 861 GKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKLESRSKDKKEKDECTP 920
++ K P + + E + + K E K K E++S +K + +P
Sbjct: 649 PEKAKSPEKEEAKSPEKAKSPVKAEAKSPE-------KAKSPVKAEAKSPEKAK----SP 697
Query: 921 TRKERKR-RHSTSPSPSRSSSGRRVKSP------SPKSERSERSERSHKESSRSRSSHKD 973
++E K + SP + S + KSP +P+ +S E + K +++S K
Sbjct: 698 VKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEA-KSPEKAKSPEKA 756
Query: 974 SPRDVSKKAKRSPS--GSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRSHKKSKKNK 1028
DV ++P+ +R+P +++SP K KS +++SP + K+ + +
Sbjct: 757 KTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKE 813
Score = 60.1 bits (144), Expect = 1e-08
Identities = 60/314 (19%), Positives = 134/314 (42%), Gaps = 23/314 (7%)
Query: 730 KSLDDDLDGVPLDATEDSKKNEPIFKVAPSKWEAVDESELEAQAVTTSKWELFDQHEESE 789
KS + V +A K P+ + A + +A + EA++ +K E+++
Sbjct: 703 KSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAK-----SPEKAK 757
Query: 790 EEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLREI-- 847
+ ++ E ++ +E+ +S + +P+KEE+ + +K S + E+ +A +EI
Sbjct: 758 TLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAK-SPLKEDAKAPEKEIPK 816
Query: 848 --ELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKL 905
E+K ++E + K+P + +E+ K +++ K+ E ++ K K +
Sbjct: 817 KEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEE 876
Query: 906 ESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGR-RVKSPSPKSERSERSERSHKES 964
+ +K K+ +KE P+P + + + VK + E++E +++ ++
Sbjct: 877 KKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDA 936
Query: 965 SRSRSS-----------HKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKK-SGKKSRS 1012
S KD+ + +KK + P K ++ S+ P K +K+
Sbjct: 937 KAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEK 996
Query: 1013 QSRSPHRSHKKSKK 1026
S + + K +K
Sbjct: 997 SSSTDQKDSKPPEK 1010
Score = 56.6 bits (135), Expect = 1e-07
Identities = 62/309 (20%), Positives = 131/309 (42%), Gaps = 17/309 (5%)
Query: 730 KSLDDDLDGVPLDATEDSKKNEPIFKVAPSKWEAVDESELEAQAVTTSKWELFDQHEESE 789
KS + V +A K P+ + A S +A + EA++ +K + ++ + E
Sbjct: 675 KSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPE 734
Query: 790 EEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLREIEL 849
+ ++ +EE E+ K++ + S K E S + E+ ++ ++E
Sbjct: 735 KAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVK 794
Query: 850 KVMKFQDEL-ESGKRPKKPGQSFQE-----QVEHYRDKLLQREKEKELERER-ERDKKDK 902
K + L E K P+K +E + E ++ +E K+ E E+ K +
Sbjct: 795 SPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTE 854
Query: 903 EKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHK 962
EK +S+ ++ +K+ P +E+K P S +V++ ++E ++ K
Sbjct: 855 EKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKES------KVEAKKEEAEDKKKVPTPEK 908
Query: 963 ESSRSRSSHKDS-PRDVSKKAKRSPSGSRT--PKRSRRSRSRSPKKSGKKSRSQSRSPHR 1019
E+ +D+ P++ ++ AK+ P ++ P + + +P+K K +++ P
Sbjct: 909 EAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTK-EEKAKKPEE 967
Query: 1020 SHKKSKKNK 1028
K K K
Sbjct: 968 KPKTEAKAK 976
Score = 53.5 bits (127), Expect = 1e-06
Identities = 54/276 (19%), Positives = 128/276 (46%), Gaps = 28/276 (10%)
Query: 757 APSKWEAVD----ESELEAQAVTTSKWELFDQHEES--EEEENQNQEEESEDEEDTQSSK 810
+P K + +D E++ A+ S + F + +S +EE ++ +S +ED ++ +
Sbjct: 752 SPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPE 811
Query: 811 SE--EHHLYSNPIKEEMT--ESKFSKYSEMSEEKRAKLREIELKVMKFQDELESGKRPKK 866
E + +P+KEE E K + + +EE++A K +++ +S K
Sbjct: 812 KEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATP------KTEEKKDSKKEEAP 865
Query: 867 PGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKLESRSKDKKEKDECTPTRKERK 926
++ + +VE ++ +++ KE ++E ++E + +DK+K+ + K+ K E K ++
Sbjct: 866 KKEAPKPKVEEKKEPAVEKPKESKVEAKKE-EAEDKKKVPTPEKEAPAKVEVKEDAKPKE 924
Query: 927 RRHSTSPSPSRSSSGRRVK-------SPSPKS---ERSERSERSHKESSRSRSSHKDSPR 976
+ P + + K +P K E++++ E K ++++ K +
Sbjct: 925 KTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSK 984
Query: 977 DVSK-KAKRSPSGSRTPKRSRRSRSRSPKKSGKKSR 1011
+ SK KA+++ S T ++ + ++ + K +
Sbjct: 985 EPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAKGK 1020
Score = 37.4 bits (85), Expect = 0.073
Identities = 52/241 (21%), Positives = 95/241 (39%), Gaps = 23/241 (9%)
Query: 10 QKASSKTRS-SDVHSSGSSDAHMDASGPSDSDMPSRTRPKSPRKHN--YRNESARESLCD 66
+KA S ++ + S +A P + P + KSP K + E+
Sbjct: 678 EKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAK 737
Query: 67 SP--HQNLSRPLLENKLKAFSIGKMSTAKRTLSKKEQEELKKKEDEKAAAEIYEEFLAAF 124
SP + S ++ KA ++ S +T +K+E K EKA + + EE +
Sbjct: 738 SPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSP- 796
Query: 125 EGSDGNKVKTFVRGGVVNAAKEEHETDEKRGKIYKPSSRFADQKNPPNQSSNERPPSLLV 184
K K+ ++ KE + +E + + ++ P + + PP
Sbjct: 797 -----EKAKSPLKEDAKAPEKEIPKKEEVKSPV--------KEEEKPQEVKVKEPPK--K 841
Query: 185 IETKKPPLKKGEKEKKKSNLELF--KEELKQIQEERDERHKTKGRLSRFEPPQSDSDGQR 242
E +K P +EKK S E KE K EE+ E K + S+ E + +++ ++
Sbjct: 842 AEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKK 901
Query: 243 R 243
+
Sbjct: 902 K 902
Score = 32.7 bits (73), Expect = 1.8
Identities = 57/261 (21%), Positives = 98/261 (37%), Gaps = 42/261 (16%)
Query: 4 KTPGGSQKASSKTRSSDVHSSGSSDAHMDASGPSDSDMPSRTRPKSPRKHNYRNESARES 63
KTP K +++ + S + P + P + K+P K + E +
Sbjct: 767 KTPA---KEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVK-- 821
Query: 64 LCDSPHQNLSRPL---LENKLKAFSIGKMSTAKRTLSKKE--QEELKKKEDEKAAAEIYE 118
SP + +P ++ K K +T KK+ +EE KKE K E +
Sbjct: 822 ---SPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKK 878
Query: 119 EFLAAFEGSDGNKVKTFVRGGVVNAAKEEHETDEKR---------GKIY-----KPSSRF 164
E A E +KV+ AK+E D+K+ K+ KP +
Sbjct: 879 E--PAVEKPKESKVE----------AKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKT 926
Query: 165 ADQKNPPNQSSNERPPSLLVIETKKPPLKKGEKEKKKSNLELFKEELKQIQEERD-ERHK 223
K P+ + + P + P K ++EK K E K E K ++++ +
Sbjct: 927 EVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEP 986
Query: 224 TKGRLSRFEPPQSDSDGQRRS 244
+K + + E +S S Q+ S
Sbjct: 987 SKPKAEKAE--KSSSTDQKDS 1005
Score = 32.3 bits (72), Expect = 2.4
Identities = 34/140 (24%), Positives = 60/140 (42%), Gaps = 14/140 (10%)
Query: 103 ELKKKEDEKAAAEIYEEFLAAFEGSDGNKVKTFVRGGVVNAAKEEHETDEKRGKIYKPSS 162
++K +E K + +E + E ++ +V V AKEE +E+ G+ +
Sbjct: 437 KVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEG 496
Query: 163 RFADQKNPPNQ--SSNERPPSLLVIETKKPP--LKKGEKEKKKSNLELFKEELKQIQEER 218
+ K+PP + +S E+ V E K P K EKE+ KS E+ +
Sbjct: 497 GEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEV----------KS 546
Query: 219 DERHKTKGRLSRFEPPQSDS 238
E+ K+ + PP++ S
Sbjct: 547 PEKAKSPAKEEAKSPPEAKS 566
Score = 32.0 bits (71), Expect = 3.1
Identities = 35/117 (29%), Positives = 49/117 (41%), Gaps = 12/117 (10%)
Query: 100 EQEELKKKEDEKAAAEIYEEFLAAFEGSDGNKVKTFVRGGVVNAAKEEHET-----DEKR 154
E+EE + KE+E E EE E ++G + +T AA E E +E +
Sbjct: 472 EEEEKEAKEEEGKEEEGGEE-----EEAEGGEEET-KSPPAEEAASPEKEAKSPVKEEAK 525
Query: 155 GKIYKPSSRFADQKNPPNQSSNERPPSLLVIETKKPP-LKKGEKEKKKSNLELFKEE 210
S + K+P S E+ S E K PP K EKE+ KS E+ E
Sbjct: 526 SPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPE 582
Score = 30.4 bits (67), Expect = 9.0
Identities = 46/230 (20%), Positives = 84/230 (36%), Gaps = 27/230 (11%)
Query: 9 SQKASSKTRSSDVHSSGSSDAHMDASGPSDSDMPSRTRPKSPRKHNYRNESARESLCDSP 68
++ +T+S + S + +A P + S KSP K E+ + SP
Sbjct: 494 AEGGEEETKSPPAEEAASPEK--EAKSPVKEEAKSPAEAKSPEKE----EAKSPAEVKSP 547
Query: 69 HQNLSRPLLENKLKAFSIGKMSTAKRTLSKKEQEELKKKEDEKAAAEIYEEFLAAFEGSD 128
+ S E K AK ++ + + K EKA + EE + E
Sbjct: 548 EKAKSPAKEEAK-------SPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKS 600
Query: 129 GNKVKTFVRGGVVNAAKEEHETDEKRGKIYKPSSRFADQKNPPNQSSNERPPSLLVIETK 188
K K+ V+ + A+ + E + K+P S E+ S E K
Sbjct: 601 PEKAKSPVKEEAKSPAEAKSPVKE-------------EAKSPAEVKSPEKAKSPTKEEAK 647
Query: 189 KPPLKKGEKEKKKSNLELFKEELKQIQEERDERHKTKGRLSRFEPPQSDS 238
P K ++++ + E K +K + + E+ K+ + P ++ S
Sbjct: 648 SPEKAKSPEKEEAKSPEKAKSPVK-AEAKSPEKAKSPVKAEAKSPEKAKS 696
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 81.3 bits (199), Expect = 4e-15
Identities = 71/277 (25%), Positives = 117/277 (42%), Gaps = 10/277 (3%)
Query: 758 PSKWEAVDESELEAQAVTTSKWELFDQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLY 817
PSK ++ + S ++ V + + E+S + +S ++ T+S + + H
Sbjct: 226 PSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRS-RPQSHSQS 284
Query: 818 SNPIK-----EEMTESKFSKYSEMSEEKRAKLREIELKVMKFQDELESGKRPKKPGQSFQ 872
+P + ++ T S+ +S RA+ R + + + +S K Q+
Sbjct: 285 RSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQS 344
Query: 873 EQVEHYRDKLLQREKEKELERERERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTS 932
R R KE R + S +KE ++R HS S
Sbjct: 345 RTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRS 404
Query: 933 PSPSRSSSGRRVKSPSPKSERS-ERSERSHKESSRSRSSHK--DSPRDVSKKAKRSPSGS 989
SP+++ R +SP +RS RS ++ SRSRS +K D R S R S S
Sbjct: 405 RSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRS 464
Query: 990 RTPKRSR-RSRSRSPKKSGKKSRSQSRSPHRSHKKSK 1025
R+P ++R RSRSRSP K S+ S S R H++S+
Sbjct: 465 RSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSR 501
Score = 77.8 bits (190), Expect = 5e-14
Identities = 67/243 (27%), Positives = 105/243 (43%), Gaps = 11/243 (4%)
Query: 793 NQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEM-----TESKFSKYSEMSEEKRAKLREI 847
++N +E SSK +H S+P KE + +K +S +A+ R
Sbjct: 356 SRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSR 415
Query: 848 ELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERD-KKDKEKLE 906
K +D S K S RD+ R K + R R K +++
Sbjct: 416 SRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSR 475
Query: 907 SRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPS-PKSERSERSERSHKESS 965
SRS K E+D ++R H S SPS+ R+ +S S + R RS ++
Sbjct: 476 SRSPSK-ERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRR 534
Query: 966 RSRSSHKDSPRDVSK--KAKRSPSGSRTPKRSR-RSRSRSPKKSGKKSRSQSRSPHRSHK 1022
+SRS +K+ R S+ +R SR+P + R R R RSP K ++ +S+S S R H
Sbjct: 535 QSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHS 594
Query: 1023 KSK 1025
+S+
Sbjct: 595 RSR 597
Score = 75.1 bits (183), Expect = 3e-13
Identities = 62/247 (25%), Positives = 95/247 (38%), Gaps = 18/247 (7%)
Query: 784 QHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAK 843
+H +S + +S + H+ NP KE S E +
Sbjct: 328 RHSQSRSHSKGKSQNQSRTPR-----RGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSS 382
Query: 844 LREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKE 903
R K +SG K+ S RD+ R K +R R R
Sbjct: 383 PR-------KESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKAR 435
Query: 904 KLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSE----RSER 959
K +D + R HS S SP+++ R +SPS + + S+ ER
Sbjct: 436 DCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKER 495
Query: 960 SHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSR-RSRSRSPKKSGKKSRSQSRSPH 1018
H+ SRS S + + S +R SR+P + R R +SRSP K +S+S+S S
Sbjct: 496 DHRR-SRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEE 554
Query: 1019 RSHKKSK 1025
R H++S+
Sbjct: 555 REHRQSR 561
Score = 72.0 bits (175), Expect = 3e-12
Identities = 64/212 (30%), Positives = 95/212 (44%), Gaps = 17/212 (8%)
Query: 828 SKFSKYSEMSEEKRAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREK 887
+K +S +A+ R K +D + G K+ R R
Sbjct: 456 NKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSS 515
Query: 888 EKELERERERD-KKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKS 946
KE + R R K++++ +SRS +K E+D +R H S SPS+ RR +S
Sbjct: 516 SKERDHRRSRSPSKERQRRQSRSPNK-ERDRSQSRSPSEEREHRQSRSPSKERDRRRWRS 574
Query: 947 PSPKSERSE-RSERSHKESSRSRSSHKDS----PRDVSKKAKRSPSGSRTP-KRSRRSRS 1000
PS + ER + RS ++ SRSRS +K S PR SK +++ S SRTP K S+S
Sbjct: 575 PSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSK--EKAHSRSRTPSKEGNHSQS 632
Query: 1001 RSPKKSGKKSRSQ-------SRSPHRSHKKSK 1025
R+ K S+S RSP R+ S+
Sbjct: 633 RTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQ 664
Score = 59.7 bits (143), Expect = 1e-08
Identities = 64/303 (21%), Positives = 119/303 (39%), Gaps = 22/303 (7%)
Query: 726 GVPIKSLDDDLDGVPLDATEDSKKNEPIFKVAPSKWEAVDESELEAQAVTTSKWELFDQH 785
G P K D P A + S+ P ++A D S + +
Sbjct: 393 GSPNKQRDHSRSRSPNKARDRSRSRSP--------YKARDRSRSRSPNKARDCSRSRSPY 444
Query: 786 EESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEK-RAKL 844
+ + +++ + + +K+ + +P KE S E + R+
Sbjct: 445 KARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPS 504
Query: 845 REIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERD-KKDKE 903
+E + + + + +R + P + R + R KE +R + R +++E
Sbjct: 505 KERQCRQSRSSSKERDHRRSRSPSKE--------RQRRQSRSPNKERDRSQSRSPSEERE 556
Query: 904 KLESRSKDK-KEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSE-RSERSH 961
+SRS K +++ KER+RR S S S R S R +SP+ +S S R+
Sbjct: 557 HRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHS--RSRSPNKQSGYSRPRASSKE 614
Query: 962 KESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRSH 1021
K SRSR+ K+ S+ + + S++ RSP ++ S++++ S SH
Sbjct: 615 KAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSH 674
Query: 1022 KKS 1024
S
Sbjct: 675 SPS 677
Score = 56.6 bits (135), Expect = 1e-07
Identities = 65/297 (21%), Positives = 113/297 (38%), Gaps = 38/297 (12%)
Query: 728 PIKSLDDDLDGVPLDATEDSKKNEPIFKVAPSKWEAVDESELEAQAVTTSKWELFDQHEE 787
P K+ D P A + S+ P +A D S + + +L +E
Sbjct: 443 PYKARDRSRSRSPNKARDHSRSRSPN--------KARDRSRSRSPSKERDHSQLGSPSKE 494
Query: 788 SEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLREI 847
+ +++ +E + + SSK +H +P KE S E + E
Sbjct: 495 RDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSE- 553
Query: 848 ELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKLES 907
+ E + P K RD+ R KE ER + R + E+ S
Sbjct: 554 -------EREHRQSRSPSKE-----------RDRRRWRSPSKERERRQSRSSSE-ERDHS 594
Query: 908 RSKD-KKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKESSR 966
RS+ K+ P +++ HS S +PS+ + + ++ S +S+ S+ + + R
Sbjct: 595 RSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKR 654
Query: 967 S--RSSHKDSPRDVSKKAKRS----PSGSRTPKRSRRSRSRSPKKS---GKKSRSQS 1014
S R+S R SK + S PSG +T + + K+ G++S S S
Sbjct: 655 SPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSSSS 711
Score = 52.0 bits (123), Expect = 3e-06
Identities = 48/174 (27%), Positives = 69/174 (39%), Gaps = 25/174 (14%)
Query: 858 LESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKLESRSKDKKEKDE 917
+ S ++ P S +V+ Y ++ ++ E K + +RS
Sbjct: 225 IPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRS-------- 276
Query: 918 CTPTRKERKRRHSTSPSPSRSSSG------RRVKSPSPKSERSERSERSHKESSRSRSSH 971
R + HS S SP RS SG RV+S S K S R+ K H
Sbjct: 277 -------RPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRH 329
Query: 972 KDSPRDVSKKAKRSPSGSRTPKRSR-RSRSRSPKKSGKKSRSQSRSPHRSHKKS 1024
S S +S + SRTP+R R + SR+P K S S+S S R H+ S
Sbjct: 330 SQSR---SHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGS 380
Score = 45.8 bits (107), Expect = 2e-04
Identities = 38/132 (28%), Positives = 56/132 (42%), Gaps = 8/132 (6%)
Query: 898 DKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERS 957
D K L+S +K PT+ R SPS S+S+ KS S K S R
Sbjct: 25 DPKPPASLKS-TKSATPNRSLVPTKPATSRNSVMSPSSSKST-----KSTSTKRAPSNRP 78
Query: 958 ERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSP 1017
+ S++R+ + S + KA ++ +R SR R+P + G SRS RSP
Sbjct: 79 SSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRG--SRSSKRSP 136
Query: 1018 HRSHKKSKKNKH 1029
R+ + H
Sbjct: 137 SRASTPGRIRTH 148
Score = 41.6 bits (96), Expect = 0.004
Identities = 38/128 (29%), Positives = 57/128 (44%), Gaps = 19/128 (14%)
Query: 919 TPTRKERKRRHSTSPSPS-RSSSGRRVKSPSPKSERSERSERSHKESSRS-------RSS 970
+P+ + + ST +PS R SS RV+S + R R+ K S S R +
Sbjct: 58 SPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGT 117
Query: 971 H---KDSPRDVSKKAKRSPSGSRTPKRSR--------RSRSRSPKKSGKKSRSQSRSPHR 1019
H + R S+ +KRSPS + TP R R SR R+P K SR +S R
Sbjct: 118 HSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPR 177
Query: 1020 SHKKSKKN 1027
+ + + +
Sbjct: 178 TSNRERSD 185
Score = 39.3 bits (90), Expect = 0.019
Identities = 31/116 (26%), Positives = 53/116 (45%), Gaps = 18/116 (15%)
Query: 925 RKRRHSTSPSPSRSSSGRRVKSP-----------SPKSERSERSERSHKESSRSRSSHKD 973
R+ S+ SPSR+S+ R+++ +P S++ +S+ S D
Sbjct: 126 RRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSD 185
Query: 974 S-PRDVSKKAKRSPSGSRTPKRSR------RSRSRSPKKSGKKSRSQSRSPHRSHK 1022
S PR++SKK+ R P GS + S ++ ++P K +S + SP S K
Sbjct: 186 SQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRK 241
Score = 38.1 bits (87), Expect = 0.043
Identities = 35/137 (25%), Positives = 59/137 (43%), Gaps = 25/137 (18%)
Query: 901 DKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSS--------SGRRVKSPSPKSE 952
++E+ +S+ ++ +K P R + +PS + S + +PSP S
Sbjct: 180 NRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSS 239
Query: 953 RSERSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRS 1012
R +S SR +S SP ++S + K S +++ +S +S S
Sbjct: 240 RKVKSYGQMIIPSREKSY---SPTEMSSRVK--------------SYNQASTRSRPQSHS 282
Query: 1013 QSRSPHRSHKKSKKNKH 1029
QSRSP RS S+K H
Sbjct: 283 QSRSPRRSRSGSQKRTH 299
>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
Length = 330
Score = 78.6 bits (192), Expect = 3e-14
Identities = 68/226 (30%), Positives = 102/226 (45%), Gaps = 37/226 (16%)
Query: 821 IKEEMTESKFSKYSEMSEEKRAK-------LREIELKVMKFQDELESGKRPKKPGQSFQE 873
I+ E ++ ++ ++ ++ R K L+E+E K + ++E E E
Sbjct: 115 IEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDED------------E 162
Query: 874 QVEHYRDKLLQREKEKELER------ERERDKKDKEKLESRSKDKKEKDECTPTRKERKR 927
+ Y+ + E + +L + E E K K SRSK + R
Sbjct: 163 DLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHS--------RSS 214
Query: 928 RHSTSPSPSRSSSGRRVKSPSPKSERSERS--ERSHKESSRSRSSHKDSPRDVSKKAKRS 985
S+SPS SRS S R +S S RS S ERS S+SRSS + S + +
Sbjct: 215 SRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSY 274
Query: 986 PSGSRTPKRSR-RSRSRSPKKSG-KKSRSQSRSPHRSHKKSKKNKH 1029
S S +P+R+R RSRSRS KK R++SRSP R H+ S + H
Sbjct: 275 SSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSH 320
Score = 56.2 bits (134), Expect = 2e-07
Identities = 51/191 (26%), Positives = 78/191 (40%), Gaps = 15/191 (7%)
Query: 796 QEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLREIELKVMKFQ 855
+++ESE EE+ + ++ L + +++ SK++ + E+ K +
Sbjct: 149 EDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRS 208
Query: 856 DELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKLESR-----SK 910
S R P S R + + + RER R + K + SR S
Sbjct: 209 SHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSS 268
Query: 911 DKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKESSRSRSS 970
+K + + ER R+ S S S SSSG R K + RS ER H+ S S SS
Sbjct: 269 PRKRSYSSSSSSPERNRKRSRSRS---SSSGDRKK----RRTRSRSPERRHRSS--SGSS 319
Query: 971 HKDSPRDVSKK 981
H S R SKK
Sbjct: 320 HSGS-RSSSKK 329
>gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]
Length = 1007
Score = 78.2 bits (191), Expect = 4e-14
Identities = 74/301 (24%), Positives = 139/301 (46%), Gaps = 65/301 (21%)
Query: 788 SEEEENQNQEEESEDEEDTQSSKSEEH---HLYSNPIKEEMTESKFSKYSEMS-----EE 839
S+ +++++ EE +D++ K ++H + KE M+ +K +K +++ E+
Sbjct: 52 SKHKKHKHSSEEDKDKKHKHKHKHKKHKRKEIIDASDKEGMSPAKRTKLDDLALLEDLEK 111
Query: 840 KRAKLR-EIELKVMK-----------------------FQDELESGKRPKKPGQSFQEQV 875
+RA ++ E++ ++M+ ++ +G R S + ++
Sbjct: 112 QRALIKAELDNELMEGKVQSGMGLILQGYESGSEEEGEIHEKARNGNRSSTRSSSTKGKL 171
Query: 876 EHYRDKLLQREKEKELERERERDKKDKEKLE----------SRSKDKKEKDECTPTRKER 925
E +K+ +++ K +ER R + DK+K + +RSK K+ K +P+++ +
Sbjct: 172 ELVDNKITTKKRSKSRSKERTRHRSDKKKSKGGIEIVKEKTTRSKSKERKKSKSPSKRSK 231
Query: 926 KR---RHSTSPSPSRSSSGRRVKSPSP-----------KSERSERSERSHKESSRSRSSH 971
+ R S SP+ R S + K+ SP KS+ ++S ++ SR R
Sbjct: 232 SQDQARKSKSPTLRRRSQEKIGKARSPTDDKVKIEDKSKSKDRKKSPIINESRSRDRGKK 291
Query: 972 KDSPRDVSKKAK--RSPSGSRTPKRSRRSRSRSPKK-------SGKKSRSQSRSPHRSHK 1022
SP D+ K+K RS S R KRS + + P K SGK++RS SR P RS K
Sbjct: 292 SRSPVDLRGKSKDRRSRSKERKSKRSETDKEKKPIKSPSKDASSGKENRSPSRRPGRSPK 351
Query: 1023 K 1023
+
Sbjct: 352 R 352
Score = 76.3 bits (186), Expect = 1e-13
Identities = 82/322 (25%), Positives = 132/322 (40%), Gaps = 61/322 (18%)
Query: 768 ELEAQAVTTSKWELFDQHEESEEEENQNQEEESED--EEDTQSSKSEEHHLYSNPIK--- 822
EL +TT K E + ++ + + + +E T SKS+E +P K
Sbjct: 172 ELVDNKITTKKRSKSRSKERTRHRSDKKKSKGGIEIVKEKTTRSKSKERKKSKSPSKRSK 231
Query: 823 --EEMTESKFSKYSEMSEEKRAKLREIELKVMKFQDELESGKRPKKP----------GQS 870
++ +SK S+EK K R +K +D+ +S R K P G+
Sbjct: 232 SQDQARKSKSPTLRRRSQEKIGKARSPTDDKVKIEDKSKSKDRKKSPIINESRSRDRGKK 291
Query: 871 FQEQVEHYRDKLLQREKEKELERERERDKKDKEKLESRSKDKKE-KDECTPTRKERKRRH 929
+ V+ +R + KE + +R K+K+ ++S SKD K+ +P+R+ +
Sbjct: 292 SRSPVDLRGKSKDRRSRSKERKSKRSETDKEKKPIKSPSKDASSGKENRSPSRRPGRSPK 351
Query: 930 STSPSPSRSSSGRRVKSPSPKSERSERS------------------ERSHKESSRSR-SS 970
S SP RR +SP RS++S ER +E R R SS
Sbjct: 352 RRSLSPKPRDKSRRSRSPLLNDRRSKQSKSPSRTLSPGRRAKSRSLERKRREPERRRLSS 411
Query: 971 HKDSPRD-------------------VSKKAKRSP--SGSRTP---KRSRRSRSRSPKKS 1006
+ PRD +++ RSP SR+P RS R RSRSP++
Sbjct: 412 PRTRPRDDILSRRERSKDASPINRWSPTRRRSRSPIRRRSRSPLRRSRSPRRRSRSPRRR 471
Query: 1007 GKKSRSQSRSPHRSHKKSKKNK 1028
+ RS+SR RS + + +
Sbjct: 472 DRGRRSRSRLRRRSRSRGGRRR 493
Score = 42.4 bits (98), Expect = 0.002
Identities = 51/244 (20%), Positives = 99/244 (40%), Gaps = 24/244 (9%)
Query: 792 ENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLREIELKV 851
E Q+ E+ E ED S KS + + E+ +++K S++ + + R+K ++ +
Sbjct: 5 ETQSLREQPE-MEDANSEKSINEE--NGEVSEDQSQNKHSRHKKKKHKHRSKHKKHKHSS 61
Query: 852 MKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKLESRSKD 911
+ +D+ K K +H R +++ ++ + + D LE K
Sbjct: 62 EEDKDKKHKHKHKHK---------KHKRKEIIDASDKEGMSPAKRTKLDDLALLEDLEKQ 112
Query: 912 KKE-KDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKESSRSRSS 970
+ K E E K + SG + E E++ ++ S+RS S+
Sbjct: 113 RALIKAELDNELMEGKVQSGMGLILQGYESGSE-----EEGEIHEKARNGNRSSTRSSST 167
Query: 971 HKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSG------KKSRSQSRSPHRSHKKS 1024
+K + S SR+ +R+R + K G K +RS+S+ +S S
Sbjct: 168 KGKLELVDNKITTKKRSKSRSKERTRHRSDKKKSKGGIEIVKEKTTRSKSKERKKSKSPS 227
Query: 1025 KKNK 1028
K++K
Sbjct: 228 KRSK 231
Score = 39.7 bits (91), Expect = 0.015
Identities = 48/243 (19%), Positives = 93/243 (38%), Gaps = 28/243 (11%)
Query: 14 SKTRSSDVHSSGSSDAHMDASGPSDSDMPSRTRPKSPRKHNYRNES-ARESLCDSPHQNL 72
S+ +S + HS H S S KH ++++ R+ + D+ +
Sbjct: 32 SEDQSQNKHSRHKKKKHKHRSKHKKHKHSSEEDKDKKHKHKHKHKKHKRKEIIDASDKEG 91
Query: 73 SRPLLENKLKAFSIGKMSTAKRTLSKKEQE-ELKKKEDEKAAAEIYEEFLAAFEGSDGNK 131
P KL ++ + +R L K E + EL + + + I + + G++
Sbjct: 92 MSPAKRTKLDDLALLEDLEKQRALIKAELDNELMEGKVQSGMGLILQGY------ESGSE 145
Query: 132 VKTFVRGGVVNAAKEEHETDEKRGKIYKPSSRFADQKNPPNQSSNERPPSLLVIETKKPP 191
+ + N + + +GK+ ++ +K ++S K+
Sbjct: 146 EEGEIHEKARNGNRSSTRSSSTKGKLELVDNKITTKKRSKSRS-------------KERT 192
Query: 192 LKKGEKEKKKSNLELFKEELKQIQEERDERHKTKGRLSRFEPPQSDSDGQRRSMDAPSRR 251
+ +K+K K +E+ KE K + + ER K+K R S S Q R +P+ R
Sbjct: 193 RHRSDKKKSKGGIEIVKE--KTTRSKSKERKKSKSPSKR-----SKSQDQARKSKSPTLR 245
Query: 252 NRS 254
RS
Sbjct: 246 RRS 248
Score = 34.3 bits (77), Expect = 0.62
Identities = 46/221 (20%), Positives = 77/221 (34%), Gaps = 32/221 (14%)
Query: 788 SEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLREI 847
S +E +++ E++ E+ S S++ + K +S + R K R
Sbjct: 307 SRSKERKSKRSETDKEKKPIKSPSKDASSGKENRSPSRRPGRSPKRRSLSPKPRDKSRRS 366
Query: 848 ELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKLES 907
++ + +S K P + + ++ + + + L R R + D
Sbjct: 367 RSPLLNDRRSKQS-KSPSRTLSPGRRAKSRSLERKRREPERRRLSSPRTRPRDDILSRRE 425
Query: 908 RSKDKKEKDECTPTRKERK---RRHSTSP------------SP----------------S 936
RSKD + +PTR+ + RR S SP SP S
Sbjct: 426 RSKDASPINRWSPTRRRSRSPIRRRSRSPLRRSRSPRRRSRSPRRRDRGRRSRSRLRRRS 485
Query: 937 RSSSGRRVKSPSPKSERSERSERSHKESSRSRSSHKDSPRD 977
RS GRR +S S E + S SS D+ D
Sbjct: 486 RSRGGRRRRSRSKVKEDKFKGSLSEGMKVEQESSSDDNLED 526
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 78.2 bits (191), Expect = 4e-14
Identities = 60/194 (30%), Positives = 96/194 (49%), Gaps = 14/194 (7%)
Query: 841 RAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKE-KELERERERDK 899
+A + E++ K+ K +E + +R KK Q +E R+K +RE+E +E +R RE ++
Sbjct: 224 KATVEELKEKLRKRTEEPDRDERLKKEKQEREE-----REKEREREREERERKRRREEEE 278
Query: 900 KDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERS---ER 956
++KE+ R + K+ + + + RR S S RS S R +S S RS +R
Sbjct: 279 REKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDR 338
Query: 957 SERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKR---SRRSRSRSPKKSGKKSRSQ 1013
SER H+ SRSR + RD RS S R R + R KKS KS S+
Sbjct: 339 SERKHR--SRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSR 396
Query: 1014 SRSPHRSHKKSKKN 1027
+ ++ +SK++
Sbjct: 397 EKQSEDTNTESKES 410
Score = 64.7 bits (156), Expect = 4e-10
Identities = 53/148 (35%), Positives = 69/148 (46%), Gaps = 16/148 (10%)
Query: 886 EKEKELERERERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVK 945
E+ KE R+R + E+L KKEK E KER+R R R K
Sbjct: 228 EELKEKLRKRTEEPDRDERL------KKEKQEREEREKEREREREERERKRRREEEEREK 281
Query: 946 SPSPKSERSERSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSR---RSRSRS 1002
ER+ ER + SRSR S + S R S+ S SR +RSR R RSRS
Sbjct: 282 ------ERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRS 335
Query: 1003 PKKSGKKSRSQSRSPHRSHKKSKKN-KH 1029
+S +K RS+SR RS + +K+ KH
Sbjct: 336 HDRSERKHRSRSRDRRRSKSRDRKSYKH 363
Score = 54.7 bits (130), Expect = 4e-07
Identities = 49/222 (22%), Positives = 89/222 (40%), Gaps = 19/222 (8%)
Query: 786 EESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLR 845
EE +E+ + EE DE + + E + E E K + E E++RA+ R
Sbjct: 228 EELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDR 287
Query: 846 EIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDK-KDKEK 904
E +K +S D+ R ++ + R RER + + +++
Sbjct: 288 E-----------------RRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDR 330
Query: 905 LESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKES 964
SRS D+ E+ + +R +R+R S + S R + KS+ E+ K+S
Sbjct: 331 RRSRSHDRSERKHRSRSR-DRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKS 389
Query: 965 SRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKS 1006
S S + D + ++K S + + S +S +S
Sbjct: 390 SVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSEGDTQS 431
Score = 52.4 bits (124), Expect = 2e-06
Identities = 37/175 (21%), Positives = 74/175 (42%), Gaps = 1/175 (0%)
Query: 783 DQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRA 842
++ E E EE + + E+E + + ++ E S + + + S + KR+
Sbjct: 258 EKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRS 317
Query: 843 KLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDK 902
+ RE + + S R ++ +S + + + K + R+RE+D+K K
Sbjct: 318 RSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSK 377
Query: 903 EKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERS 957
EK E R D K+ + +R+++ +T S + + S KSE +S
Sbjct: 378 EK-EKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSEGDTQS 431
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 78.2 bits (191), Expect = 4e-14
Identities = 60/194 (30%), Positives = 96/194 (49%), Gaps = 14/194 (7%)
Query: 841 RAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKE-KELERERERDK 899
+A + E++ K+ K +E + +R KK Q +E R+K +RE+E +E +R RE ++
Sbjct: 224 KATVEELKEKLRKRTEEPDRDERLKKEKQEREE-----REKEREREREERERKRRREEEE 278
Query: 900 KDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERS---ER 956
++KE+ R + K+ + + + RR S S RS S R +S S RS +R
Sbjct: 279 REKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDR 338
Query: 957 SERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKR---SRRSRSRSPKKSGKKSRSQ 1013
SER H+ SRSR + RD RS S R R + R KKS KS S+
Sbjct: 339 SERKHR--SRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSR 396
Query: 1014 SRSPHRSHKKSKKN 1027
+ ++ +SK++
Sbjct: 397 EKQSEDTNTESKES 410
Score = 64.7 bits (156), Expect = 4e-10
Identities = 53/148 (35%), Positives = 69/148 (46%), Gaps = 16/148 (10%)
Query: 886 EKEKELERERERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVK 945
E+ KE R+R + E+L KKEK E KER+R R R K
Sbjct: 228 EELKEKLRKRTEEPDRDERL------KKEKQEREEREKEREREREERERKRRREEEEREK 281
Query: 946 SPSPKSERSERSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSR---RSRSRS 1002
ER+ ER + SRSR S + S R S+ S SR +RSR R RSRS
Sbjct: 282 ------ERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRS 335
Query: 1003 PKKSGKKSRSQSRSPHRSHKKSKKN-KH 1029
+S +K RS+SR RS + +K+ KH
Sbjct: 336 HDRSERKHRSRSRDRRRSKSRDRKSYKH 363
Score = 54.7 bits (130), Expect = 4e-07
Identities = 49/222 (22%), Positives = 89/222 (40%), Gaps = 19/222 (8%)
Query: 786 EESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLR 845
EE +E+ + EE DE + + E + E E K + E E++RA+ R
Sbjct: 228 EELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDR 287
Query: 846 EIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDK-KDKEK 904
E +K +S D+ R ++ + R RER + + +++
Sbjct: 288 E-----------------RRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDR 330
Query: 905 LESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKES 964
SRS D+ E+ + +R +R+R S + S R + KS+ E+ K+S
Sbjct: 331 RRSRSHDRSERKHRSRSR-DRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKS 389
Query: 965 SRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKS 1006
S S + D + ++K S + + S +S +S
Sbjct: 390 SVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSEGDTQS 431
Score = 52.4 bits (124), Expect = 2e-06
Identities = 37/175 (21%), Positives = 74/175 (42%), Gaps = 1/175 (0%)
Query: 783 DQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRA 842
++ E E EE + + E+E + + ++ E S + + + S + KR+
Sbjct: 258 EKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRS 317
Query: 843 KLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDK 902
+ RE + + S R ++ +S + + + K + R+RE+D+K K
Sbjct: 318 RSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSK 377
Query: 903 EKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERS 957
EK E R D K+ + +R+++ +T S + + S KSE +S
Sbjct: 378 EK-EKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSEGDTQS 431
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 77.8 bits (190), Expect = 5e-14
Identities = 53/154 (34%), Positives = 73/154 (47%), Gaps = 13/154 (8%)
Query: 885 REKEKELERERERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRV 944
RE + + E DKK++++ SRS+ + + TP+ +R S S S S S R
Sbjct: 227 REAQSLISAAIEPDKKEEKRRHSRSRSRSRRRR-TPSSSRHRRSRSRSRRRSHSKSRSRR 285
Query: 945 KSPSPKSERSERSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSR-------- 996
+S SP+ RS ER + S S++ K K++K P T +RSR
Sbjct: 286 RSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRR 345
Query: 997 ---RSRSRSPKKSGKKSRSQSRSPH-RSHKKSKK 1026
RS +RSPKK R SRSP R HKK KK
Sbjct: 346 RRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKK 379
Score = 63.5 bits (153), Expect = 1e-09
Identities = 56/247 (22%), Positives = 103/247 (41%), Gaps = 25/247 (10%)
Query: 786 EESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLR 845
+E EE + +E +S + K EE +S + S+ + S +R++ R
Sbjct: 217 KEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSR----SRSRSRRRRTPSSSRHRRSRSR 272
Query: 846 EIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKL 905
+ S R ++ +S + + H R++ + + + R++ K+DKEK
Sbjct: 273 S--------RRRSHSKSRSRRRSKSPRRRRSHSRER---GRRSRSTSKTRDKKKEDKEKK 321
Query: 906 ESRSKDKK----EKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSH 961
S++ K + + R+R S + SP + S +R S SP R ++ ++
Sbjct: 322 RSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKD 381
Query: 962 KESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRSH 1021
K+ RSR + R SKK K S + R R+S S K + + + S
Sbjct: 382 KDKERSRDERE---RSTSKKKK---SKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSE 435
Query: 1022 KKSKKNK 1028
K+ K+ K
Sbjct: 436 KEKKEEK 442
Score = 50.8 bits (120), Expect = 6e-06
Identities = 53/248 (21%), Positives = 93/248 (37%), Gaps = 49/248 (19%)
Query: 784 QHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAK 843
+H S + +S ++S + H + T K E E+KR+K
Sbjct: 265 RHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSK 324
Query: 844 L-------------REIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKE 890
E + + + S K+P+ P + R K +EK+K+
Sbjct: 325 TPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHK---KEKKKD 381
Query: 891 LERERERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPK 950
++ER RD++++ S SK KK KD+ K+R+R +S S + VK +
Sbjct: 382 KDKERSRDERER----STSKKKKSKDK----EKDRER---------KSESDKDVKQVTRD 424
Query: 951 SERSERSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKS 1010
+ E+ S KE KK ++ P + +PK S + S ++S
Sbjct: 425 YDEEEQGYDSEKE----------------KKEEKKPIETGSPKTKECSVEKGTGDSLRES 468
Query: 1011 RSQSRSPH 1018
+ H
Sbjct: 469 KVNGDDHH 476
Score = 41.6 bits (96), Expect = 0.004
Identities = 24/94 (25%), Positives = 42/94 (44%)
Query: 932 SPSPSRSSSGRRVKSPSPKSERSERSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRT 991
SPS +S + ++ + ++ + E + + S + +R+PS SR
Sbjct: 207 SPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRH 266
Query: 992 PKRSRRSRSRSPKKSGKKSRSQSRSPHRSHKKSK 1025
+ RSR RS KS + RS+S RSH + +
Sbjct: 267 RRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRER 300
Score = 41.2 bits (95), Expect = 0.005
Identities = 31/114 (27%), Positives = 48/114 (42%), Gaps = 4/114 (3%)
Query: 919 TPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKESSRSRSSHKDSP--- 975
+P+ K + R + + S + + ++ E R + SRSR S
Sbjct: 207 SPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRH 266
Query: 976 -RDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRSHKKSKKNK 1028
R S+ +RS S SR+ +RS+ R R + RS+S S R KK K K
Sbjct: 267 RRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEK 320
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 77.0 bits (188), Expect = 8e-14
Identities = 49/179 (27%), Positives = 86/179 (48%), Gaps = 6/179 (3%)
Query: 852 MKFQDELE--SGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKLESRS 909
+K EL+ S KP + + + R + +R++E+E ER+RER KK+K+K + R
Sbjct: 11 VKLNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRE 70
Query: 910 KDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKESSRSRS 969
+ K+ + + K+RK R + +R + + ER ++ ER KE R
Sbjct: 71 RGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKER--KERERENK 128
Query: 970 SHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRSHKKSKKNK 1028
++ R +K KR R +R +R R R KK K+ R + R +R +K ++ +
Sbjct: 129 QRRERKRKKRRKKKRRKERKREKERGKRERKR--KKRKKEEREKKRERNRKERKKERER 185
Score = 75.1 bits (183), Expect = 3e-13
Identities = 60/207 (28%), Positives = 94/207 (45%), Gaps = 22/207 (10%)
Query: 821 IKEEMTESKFSKYSEMSE-EKRAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYR 879
I + T+ + + E E EKR + RE E K E GK+ KK + + E R
Sbjct: 25 ISKPCTQRESERKKERREREKRKREREKERK-------RERGKKEKKKRKKRERGKERER 77
Query: 880 DKLLQREKEKELERERERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSS 939
K +REK+++ RE+ER K+ KEK + K + ++ +KERK R R +
Sbjct: 78 -KRKEREKQRKERREKERRKRKKEKKKRERKQRGRRER--KKKKERKER-------EREN 127
Query: 940 SGRRVKSPSPKSERSERSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSR 999
RR + + ++ R ER +E R + K R KK +R R K ++ R
Sbjct: 128 KQRRERKRKKRRKKKRRKERK-REKERGKRERKRKKR---KKEEREKKRERNRKERKKER 183
Query: 1000 SRSPKKSGKKSRSQSRSPHRSHKKSKK 1026
R ++ KK R + R + KK +K
Sbjct: 184 ERKERRERKKERKKERRKKKERKKDRK 210
Score = 66.2 bits (160), Expect = 1e-10
Identities = 48/195 (24%), Positives = 84/195 (43%), Gaps = 15/195 (7%)
Query: 783 DQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRA 842
+ + E E + ++ E E E + K E+ +E E K + + +E+R
Sbjct: 33 ESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKER-ERKRKEREKQRKERRE 91
Query: 843 KLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDK 902
K R K K ++ + G+R +K K ++E+E+E ++ RER +K +
Sbjct: 92 KERRKRKKEKKKRERKQRGRRERKK-------------KKERKERERENKQRRERKRKKR 138
Query: 903 EKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHK 962
K + R + K+EK+ RK RK+R R + + K + ER ER + K
Sbjct: 139 RKKKRRKERKREKERGKRERK-RKKRKKEEREKKRERNRKERKKERERKERRERKKERKK 197
Query: 963 ESSRSRSSHKDSPRD 977
E + + KD D
Sbjct: 198 ERRKKKERKKDRKTD 212
Score = 63.5 bits (153), Expect = 1e-09
Identities = 48/204 (23%), Positives = 95/204 (46%), Gaps = 18/204 (8%)
Query: 822 KEEMTESKFSKYSEMSEEKRAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDK 881
+ E + + + E ++ + RE K K + + E GK ++ + ++Q + R+K
Sbjct: 33 ESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREK 92
Query: 882 LLQREKEKELERER------ERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSP 935
++ K+++ +RER ER KK KE+ E ++K+ ++ R+++KRR
Sbjct: 93 ERRKRKKEKKKRERKQRGRRERKKK-KERKERERENKQRRERKRKKRRKKKRRKERKREK 151
Query: 936 SRSSSGRRVKSPSPKSERSERSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRS 995
R R+ K K ER ++ ER+ KE + R +K +R R +R
Sbjct: 152 ERGKRERKRKK-RKKEEREKKRERNRKERKKER----------ERKERRERKKERKKERR 200
Query: 996 RRSRSRSPKKSGKKSRSQSRSPHR 1019
++ + +K+ +++ SQ P R
Sbjct: 201 KKKERKKDRKTDRQTDSQVFRPLR 224
Score = 55.5 bits (132), Expect = 3e-07
Identities = 41/161 (25%), Positives = 80/161 (49%), Gaps = 14/161 (8%)
Query: 784 QHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAK 843
Q +E E+E + +++E + E Q + E K++ + + ++ E++ K
Sbjct: 85 QRKERREKERRKRKKEKKKRERKQRGRRER--------KKKKERKERERENKQRRERKRK 136
Query: 844 LREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKE 903
R + + + + E E GKR +K + +E+ E R++ KE++ ERER K+ +E
Sbjct: 137 KRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRER---NRKERKKERER---KERRE 190
Query: 904 KLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRV 944
+ + R K++++K E RK ++ S P R S+ RV
Sbjct: 191 RKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNRV 231
Score = 39.3 bits (90), Expect = 0.019
Identities = 29/151 (19%), Positives = 64/151 (42%)
Query: 760 KWEAVDESELEAQAVTTSKWELFDQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSN 819
K E E E + + + E ++ ++E + +E + + + K + N
Sbjct: 68 KRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKEREREN 127
Query: 820 PIKEEMTESKFSKYSEMSEEKRAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYR 879
+ E K K E KR K R + K + + E K+ ++ + +++ E
Sbjct: 128 KQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKE 187
Query: 880 DKLLQREKEKELERERERDKKDKEKLESRSK 910
+ ++E++KE +++ER K K ++ S+
Sbjct: 188 RRERKKERKKERRKKKERKKDRKTDRQTDSQ 218
Score = 38.1 bits (87), Expect = 0.043
Identities = 42/183 (22%), Positives = 74/183 (40%), Gaps = 17/183 (9%)
Query: 45 TRPKSPRKHNYRNESARESLCDSPHQNLSRPLLENKLKAFSIGKMSTAKRTLSKKEQEEL 104
T+ +S RK R R+ + + + K K GK KR +K+++E
Sbjct: 30 TQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKER 89
Query: 105 KKKEDEKAAAEIYEEFLAAFEGSDGNKVKTFVRGGVVNAAKEEHETDEKRGKIYKPSSRF 164
++KE K E + + K K ++E E + K+ + K R
Sbjct: 90 REKERRKRKKEKKKRERKQRGRRERKKKKE----------RKERERENKQRRERKRKKRR 139
Query: 165 ADQKNPPNQSSNERPPSLLVIETKKPPLKKGEKEKKKSNLELFKEELKQIQEERDERHKT 224
++ + ER E K+ KK E+EKK+ E ++E K+ +E ++ R +
Sbjct: 140 KKKRRKERKREKERGKR----ERKRKKRKKEEREKKR---ERNRKERKKERERKERRERK 192
Query: 225 KGR 227
K R
Sbjct: 193 KER 195
Score = 31.2 bits (69), Expect = 5.3
Identities = 25/109 (22%), Positives = 47/109 (43%), Gaps = 5/109 (4%)
Query: 145 KEEHETDEKRGKIYKPSSRFADQKNPPNQSSNERPPSLLVIETKKPPLKKGEKEKKKSNL 204
KE E ++++ + K R +K + ER E K+ +K KE+++
Sbjct: 38 KERREREKRKREREKERKRERGKKEKKKRKKRERGKER---ERKRKEREKQRKERREKER 94
Query: 205 ELFKEELKQIQEERDERHKTKGRLSRFEPPQSDSDGQRRSMDAPSRRNR 253
K+E K+ + ++ R + K + R E + + QRR RR +
Sbjct: 95 RKRKKEKKKRERKQRGRRERKKKKERKERERENK--QRRERKRKKRRKK 141
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 76.3 bits (186), Expect = 1e-13
Identities = 63/205 (30%), Positives = 95/205 (46%), Gaps = 21/205 (10%)
Query: 822 KEEMTESKFSKYSEMSEEKRAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDK 881
K+E +E S + R++ R E K K +E G++ + +S + + +DK
Sbjct: 23 KKEQSEVSVSPRASKHHYSRSRSRSRERK-RKSDNE---GRKHRSRSRSKEGRRHESKDK 78
Query: 882 LLQREKEKELERERERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSG 941
++ K +E + K +E+L S E E RKERK S S SRS
Sbjct: 79 SSKKHKSEEHNDKEHSSDKGRERLNS-----SENGEDRHKRKERKSSRGRSHSRSRSR-- 131
Query: 942 RRVKSPSPKSERSERSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSR 1001
ER RS ++ SRSRS + R S++ K+S S SR KR RSRSR
Sbjct: 132 ----------ERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSR 181
Query: 1002 SPKKSGKKSRSQSRSPHRSHKKSKK 1026
S + ++RS+SR+ RS + K+
Sbjct: 182 SRSRHRHRTRSRSRTRSRSRDRKKR 206
Score = 68.2 bits (165), Expect = 4e-11
Identities = 65/233 (27%), Positives = 100/233 (42%), Gaps = 28/233 (12%)
Query: 790 EEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLREIEL 849
E+ + +++++ E E + S ++ +HH +S+ S E++ K
Sbjct: 14 EKTSPDRDKKKEQSEVSVSPRASKHH--------------YSRSRSRSRERKRKSDNEGR 59
Query: 850 KVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKLESRS 909
K E + K S + + E + DK E + RER ++ E R
Sbjct: 60 KHRSRSRSKEGRRHESKDKSSKKHKSEEHNDK----EHSSDKGRERLNSSENGEDRHKRK 115
Query: 910 KDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKESSRSRS 969
+ K + + R+RRH RS S R KS S ER + RS +E +SRS
Sbjct: 116 ERKSSRGRSHSRSRSRERRH-------RSRSRERKKSRSRSRERKKSRSRS-RERKKSRS 167
Query: 970 SHKDSPRDV-SKKAKRSPSGSRTPKRSR-RSRSRSPKKSGKKSRSQSRSPHRS 1020
++ R + S+ RS RT RSR RSRSR KK +K R SRS R+
Sbjct: 168 RSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRT 220
Score = 65.9 bits (159), Expect = 2e-10
Identities = 51/162 (31%), Positives = 75/162 (46%), Gaps = 18/162 (11%)
Query: 873 EQVEHYRDKLLQREKEKELERERERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTS 932
E+ RDK ++++ E+ K + SRS+++K K + RK R R
Sbjct: 14 EKTSPDRDK---KKEQSEVSVSPRASKHHYSRSRSRSRERKRKSD-NEGRKHRSR----- 64
Query: 933 PSPSRSSSGRRVKSPSPKSERSERSERSHKESS------RSRSSHKDSPRDVSKKAKRSP 986
SRS GRR +S S++ + E + KE S R SS R K+ K S
Sbjct: 65 ---SRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSR 121
Query: 987 SGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRSHKKSKKNK 1028
S + RSR R RS + KKSRS+SR +S +S++ K
Sbjct: 122 GRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERK 163
Score = 63.9 bits (154), Expect = 7e-10
Identities = 58/181 (32%), Positives = 82/181 (45%), Gaps = 13/181 (7%)
Query: 857 ELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKD-KEKLESRSKDKKEK 915
E S R KK QS R + + ER+R+ D + K + SRSK+ +
Sbjct: 14 EKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRH 73
Query: 916 DECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSER-SHKESSRSRS-SHKD 973
+ + K+ K S R+ S +R +R ER S + S SRS S +
Sbjct: 74 ESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRER 133
Query: 974 SPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGK---------KSRSQSRSPHRSHKKS 1024
R S++ K+S S SR K+SR SRSR KKS +SRS+SRS HR +S
Sbjct: 134 RHRSRSRERKKSRSRSRERKKSR-SRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRS 192
Query: 1025 K 1025
+
Sbjct: 193 R 193
Score = 51.2 bits (121), Expect = 5e-06
Identities = 47/205 (22%), Positives = 90/205 (43%), Gaps = 17/205 (8%)
Query: 784 QHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAK 843
+HE ++ +++ EE D+E SS L S+ E+ + K K S R++
Sbjct: 72 RHESKDKSSKKHKSEEHNDKE--HSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSR 129
Query: 844 LREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKE 903
RE + S R +K +S + + R + +R+K + RER+R + +
Sbjct: 130 SRERRHR---------SRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRS 180
Query: 904 KLESRSKDKKEKDECTPTR-KERKRRHSTSPSPSRSSSGRRVKSPSP---KSERSERSER 959
+ SR + + T +R ++RK+R SRS S R SP P ++ + E
Sbjct: 181 RSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLS--RTPSPPPFRGRNTAMDAQEA 238
Query: 960 SHKESSRSRSSHKDSPRDVSKKAKR 984
+ R++ + +++ +K K+
Sbjct: 239 LARRLERAKKLQEQREKEMVEKQKQ 263
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 73.6 bits (179), Expect = 9e-13
Identities = 60/272 (22%), Positives = 117/272 (43%), Gaps = 28/272 (10%)
Query: 783 DQHEESEEEENQNQ-----EEESED----EEDTQSSKSEEHHLYSNPIKEEMTESKFSKY 833
++HE+ E+E + Q +EE D EE+T+ + E +EE ++ K
Sbjct: 432 ERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKL 491
Query: 834 SEMSEEKRAKLREIELKV---------MKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQ 884
E ++ + RE +L+ +K Q+E E ++ + Q + + E R++LL+
Sbjct: 492 EEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLK 551
Query: 885 REKEKELERERERDKKDKEKLESRSKDKKEKDECTPTR---------KERKRRHSTSPSP 935
RE+EK LE+ER + +E+ E R + K ++E R ++R +R
Sbjct: 552 REEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLE 611
Query: 936 SRSSSGRRVKSPSPKSERSERSERS-HKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKR 994
+R+K P+ ER ++ +S +E R + ++ ++ KR R +R
Sbjct: 612 QEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQR 671
Query: 995 SRRSRSRSPKKSGKKSRSQSRSPHRSHKKSKK 1026
+R ++ Q ++ R + K
Sbjct: 672 LKREHEEERREQELAEEEQEQARERIKSRIPK 703
Score = 67.4 bits (163), Expect = 7e-11
Identities = 55/265 (20%), Positives = 110/265 (41%), Gaps = 24/265 (9%)
Query: 783 DQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRA 842
+Q + E+EE ++Q + E+E Q K E+ +K E E E E +
Sbjct: 564 EQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERL-----EQEERREQ 618
Query: 843 KLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKE-----LERERER 897
+L+ E + + Q L+S ++ ++ Q + + + R++ L+RE+E+E L+RE E
Sbjct: 619 RLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEE 678
Query: 898 DKKDKEKLESRSKDKKEKDECT------PTRKERKRRHSTSPSPSRSSSGRRVKSPSPKS 951
+++++E E + +E+ + E R S S R G+R + +
Sbjct: 679 ERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEK 738
Query: 952 ERSERSERSHKESSRSRSSHKDSPR--------DVSKKAKRSPSGSRTPKRSRRSRSRSP 1003
R SE +E R+ ++ + +K++R R R R
Sbjct: 739 RRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQL 798
Query: 1004 KKSGKKSRSQSRSPHRSHKKSKKNK 1028
+ ++ R Q P K+ ++ +
Sbjct: 799 RAEERQQREQRFLPEEEEKEQRRRQ 823
Score = 66.2 bits (160), Expect = 1e-10
Identities = 59/307 (19%), Positives = 134/307 (43%), Gaps = 22/307 (7%)
Query: 743 ATEDSKKNEPIFKVAPSKWEAVDESELEA-QAVTTSKWELFDQHEESEEEENQNQEEESE 801
A E+ ++ K KW+ ESE +A Q+ S+ + +E+E + + ESE
Sbjct: 686 AEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESE 745
Query: 802 ----DEEDTQSSKSEEHHL------YSNPIKEEMTESKFSKYSEMSEEKRAKLR-----E 846
+EE + EE + K E + S + E++ +LR +
Sbjct: 746 LQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQ 805
Query: 847 IELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKLE 906
E + + ++E E +R ++ + + +E ++L +RE+ ++L+ E + ++D+E+
Sbjct: 806 REQRFLPEEEEKEQRRRQRREREKELQFLEE-EEQLQRRERAQQLQEEEDGLQEDQERRR 864
Query: 907 SRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRR----VKSPSPKSERSERSERSHK 962
S+ + + +K + ++RRH+ P+ R+ ++ + +R ER +R +
Sbjct: 865 SQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQ 924
Query: 963 ESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRSHK 1022
E R + ++ + + R +R R+ R + K K+ + P + +
Sbjct: 925 EQERQYREEEQLQQEEEQLLREEREKRRRQERERQYR-KDKKLQQKEEQLLGEEPEKRRR 983
Query: 1023 KSKKNKH 1029
+ ++ K+
Sbjct: 984 QEREKKY 990
Score = 62.8 bits (151), Expect = 2e-09
Identities = 61/278 (21%), Positives = 117/278 (42%), Gaps = 31/278 (11%)
Query: 780 ELFDQHEES----EEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKE--EMTESKFSKY 833
E Q EE E E+ + QE E + +D + + EE L P K + E K+ +
Sbjct: 934 EQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREE 993
Query: 834 SEMSEEKRAKLREIELKVMK------------FQDELESGKRPKKPGQSFQEQVEHYRDK 881
E+ +E+ LRE K + Q E E R ++ + QE+ YR++
Sbjct: 994 EELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREE 1053
Query: 882 L-LQREKEKELERERERDKKDKEKLESRSKDKKEKDECTPTRKE-RKRRHSTSPSPSRSS 939
LQ+E+E+ L ERE ++ + + + R +++ +++E R+E KRR R
Sbjct: 1054 EELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREE 1113
Query: 940 SGRRVKSPSPKSERSERSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSR 999
++ + R ER +R +E R ++ ++ + + P R + R+ R
Sbjct: 1114 E--ELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYR 1171
Query: 1000 SRSP---------KKSGKKSRSQSRSPHRSHKKSKKNK 1028
++ +K R + +R ++ ++ K
Sbjct: 1172 EEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQK 1209
Score = 60.8 bits (146), Expect = 6e-09
Identities = 52/272 (19%), Positives = 116/272 (42%), Gaps = 20/272 (7%)
Query: 760 KWEAVDESELEAQAVTTSKWELFDQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSN 819
+W ++E E Q + +Q E E+ + +EEE Q +SE+
Sbjct: 487 RWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQ----QRLRSEQQ----- 537
Query: 820 PIKEEMTESKFSKYSEMSEEKRAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYR 879
++ E E + + + EEKR + E ++ + Q+E ++ + Q
Sbjct: 538 -LRREQEERR-EQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQE 595
Query: 880 DKLLQREKEKELERERERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSS 939
++L QR K +E+ER E++++ +++L+ +++ + + + ++ +RR +
Sbjct: 596 ERLEQRLKREEVER-LEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQER 654
Query: 940 SGRRVKSPSPKSERSERSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSR 999
+R+K + +R +R H+E R + ++ ++ K SR PK +
Sbjct: 655 REQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIK-----SRIPKWQWQLE 709
Query: 1000 SRSPKKSGK---KSRSQSRSPHRSHKKSKKNK 1028
S + + K + R Q R ++ K+ +
Sbjct: 710 SEADARQSKVYSRPRKQEGQRRRQEQEEKRRR 741
Score = 59.7 bits (143), Expect = 1e-08
Identities = 48/231 (20%), Positives = 104/231 (45%), Gaps = 7/231 (3%)
Query: 784 QHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAK 843
+ E+ +EEE Q Q E E+EE Q K E L +EE + + + ++ ++ +
Sbjct: 256 EEEKLQEEEPQRQRELQEEEE--QLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEE 313
Query: 844 LREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKE 903
RE + + + Q+ E ++ ++ Q + + E R++ L+RE+E+E ++ R ++++E
Sbjct: 314 RREQQEERREQQERRE--QQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEE 371
Query: 904 KLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSE-RSERSERSHK 962
+ E + + +++ R+E++ R R RR + + + R E+ R +
Sbjct: 372 RREQQLRREQQLRREQQLRREQQLRR--EQQLRREQQLRREQQLRREQQLRREQQLRREQ 429
Query: 963 ESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQ 1013
E R H+ R+ K ++ + R ++ + R Q
Sbjct: 430 EEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQ 480
Score = 59.7 bits (143), Expect = 1e-08
Identities = 53/224 (23%), Positives = 105/224 (46%), Gaps = 21/224 (9%)
Query: 783 DQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRA 842
+Q EEEE +EE + Q + E +E++ + + E E++R
Sbjct: 902 EQQLLQEEEEELQREEREKRRRQEQERQYRE--------EEQLQQEEEQLLREEREKRRR 953
Query: 843 KLREIEL---KVMKFQDELESGKRPKKPGQSFQEQVEHYR-DKLLQREKEKELERERERD 898
+ RE + K ++ ++E G+ P+K + QE+ + YR ++ LQ+E+E+ L ERE+
Sbjct: 954 QERERQYRKDKKLQQKEEQLLGEEPEK--RRRQEREKKYREEEELQQEEEQLLREEREKR 1011
Query: 899 KKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSER---SE 955
++ + + + R KD+ +++E R+ER++R R R + + E+ E
Sbjct: 1012 RRQEWERQYRKKDELQQEEEQLLREEREKRR----LQERERQYREEEELQQEEEQLLGEE 1067
Query: 956 RSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSR 999
R R +E R ++ ++ + + P R +R R+ R
Sbjct: 1068 RETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCR 1111
Score = 59.3 bits (142), Expect = 2e-08
Identities = 54/300 (18%), Positives = 126/300 (42%), Gaps = 19/300 (6%)
Query: 748 KKNEPIFKVAPSKWEAVDESELEAQAVTTSKWELFDQHEESEEEENQNQEEES------- 800
K+ E ++A + ++ + LE + EL+ Q +E +E E + EEE
Sbjct: 140 KRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGH 199
Query: 801 -----EDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLREIELKVMKFQ 855
DEE + + E K++ + + + EEK + RE L+ + +
Sbjct: 200 ETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEK 259
Query: 856 DELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKE------LERERERDKKDKEKLESRS 909
+ E +R ++ Q +EQ+ + L+RE+++E L RE++ +K +E+ +
Sbjct: 260 LQEEEPQRQREL-QEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQ 318
Query: 910 KDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKESSRSRS 969
++++E+ E ++ER+ + R R + + E+ R E+ + +
Sbjct: 319 EERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLR 378
Query: 970 SHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRSHKKSKKNKH 1029
+ R+ + ++ + +R ++ R + ++ R + + ++ + KH
Sbjct: 379 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKH 438
Score = 59.3 bits (142), Expect = 2e-08
Identities = 58/268 (21%), Positives = 113/268 (42%), Gaps = 11/268 (4%)
Query: 766 ESELEAQAVTTSKWELFDQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEM 825
E E + + E Q SE++ + QEE E + K E +K E
Sbjct: 512 EERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQ 571
Query: 826 TESKFSKYSEMSEEKRAKLR---EIELKVMKFQDELESGKRPKKPGQSF-QEQVEHYRDK 881
E + E ++ +L+ E L+ ++E+E ++ ++ Q +E+ E R +
Sbjct: 572 EERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQ 631
Query: 882 LLQREKEKELERERERDKKDKEKLESRSKDKKEKDECTPTRK---ERKRRHSTSPSPSRS 938
L + +E+E R+++ ++ +E+ E R K ++E++ K E +RR +
Sbjct: 632 QLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQE 691
Query: 939 SSGRRVKSPSPKSE---RSERSERSHKESSRSRSSHKDSPR-DVSKKAKRSPSGSRTPKR 994
+ R+KS PK + SE R K SR R R + +K +R S + +
Sbjct: 692 QARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEE 751
Query: 995 SRRSRSRSPKKSGKKSRSQSRSPHRSHK 1022
R R + ++ + Q ++ +S +
Sbjct: 752 ERAHRQQQEEEQRRDFTWQWQAEEKSER 779
Score = 58.9 bits (141), Expect = 2e-08
Identities = 48/268 (17%), Positives = 122/268 (45%), Gaps = 11/268 (4%)
Query: 765 DESELEAQAVTTSKWELFDQHEESEEEE-NQNQEEESEDEEDTQSSKSEEHHLYSNPIKE 823
+E E Q + E +Q EE E++ + QEE E + + + +E
Sbjct: 311 EEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEE 370
Query: 824 EMTESKFSKYSEMSEEKRAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLL 883
E E + + ++ E++ + RE +L + + +L ++ ++ Q +EQ + R++ L
Sbjct: 371 ERREQQLRREQQLRREQQLR-REQQL---RREQQLRREQQLRREQQLRREQ-QLRREQQL 425
Query: 884 QREKEKELERERERDKKDKEKLESRSKDKKE---KDECTPTRKERKRRHSTSPSPSRSSS 940
+RE+E+E ++ ++ +++L+ +++++ ++E T ++ +R+
Sbjct: 426 RREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERR 485
Query: 941 GRRVKSPSPKSERSERSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRS 1000
R +K + ER E+ ER ++ R + ++ ++ +R R+ ++ RR +
Sbjct: 486 ERWLK--LEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQE 543
Query: 1001 RSPKKSGKKSRSQSRSPHRSHKKSKKNK 1028
++ K+ + R ++ K+ +
Sbjct: 544 ERREQLLKREEEKRLEQERREQRLKREQ 571
Score = 58.2 bits (139), Expect = 4e-08
Identities = 52/243 (21%), Positives = 110/243 (45%), Gaps = 20/243 (8%)
Query: 786 EESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLR 845
EE E+ Q +E + +EE+ Q + + + + E ++ + E+ +E+ LR
Sbjct: 1096 EEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLR 1155
Query: 846 EIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKL 905
E K + + ELE R +E+++ ++LL+ E+EK +ERER +++E+L
Sbjct: 1156 EEPEK--RRRQELERQYRE-------EEELQQEEEQLLREEQEKR-RQERERQYREEEEL 1205
Query: 906 ESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKESS 965
+ + + ++ +DE +++ P + ++ R K K +E+ +
Sbjct: 1206 QRQKRKQRYRDE------DQRSDLKWQWEPEKENAVRDNKVYC-KGRENEQFRQLEDSQL 1258
Query: 966 RSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRSHKKSK 1025
R R S +D + ++ +R R R + R R + + R + + R +KS+
Sbjct: 1259 RDRQSQQDLQHLLGEQQERDREQER---RRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQ 1315
Query: 1026 KNK 1028
+ K
Sbjct: 1316 EEK 1318
Score = 57.8 bits (138), Expect = 5e-08
Identities = 46/231 (19%), Positives = 101/231 (43%), Gaps = 9/231 (3%)
Query: 762 EAVDESELEAQAVTTSKWELFDQHEESEEEENQNQEEES---EDEEDTQSSKSEEHHLYS 818
+ + E E E Q K +Q + EEE QEEE E+ E + + E +
Sbjct: 904 QLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKD 963
Query: 819 NPIKEEMTESKFSKYSEMSEEKRAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHY 878
++++ + + + ++R K E ++ + +++L +R K+ Q ++ Q
Sbjct: 964 KKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRK- 1022
Query: 879 RDKLLQREK-----EKELERERERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSP 933
+D+L Q E+ E+E R +ER+++ +E+ E + ++++ E TR+ ++
Sbjct: 1023 KDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRK 1082
Query: 934 SPSRSSSGRRVKSPSPKSERSERSERSHKESSRSRSSHKDSPRDVSKKAKR 984
++ P+ R + ER +E + + R+ +K +R
Sbjct: 1083 EEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRR 1133
Score = 56.6 bits (135), Expect = 1e-07
Identities = 49/291 (16%), Positives = 130/291 (44%), Gaps = 8/291 (2%)
Query: 741 LDATEDSKKNEPIFKVAPSKWEAVDESELEAQAVTTSKWELFDQHEESEEEENQNQEEES 800
L+ + +++E +++ +W+ +E E + + + K + EE +EE + E
Sbjct: 161 LEQRDRQRRDEELWRQR-QEWQEREERRAEEEQLQSCKGH---ETEEFPDEEQLRRRELL 216
Query: 801 EDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLREIE-LKVMKFQDELE 859
E + K ++ + + +E E ++ K + ++ KL+E E + + Q+E E
Sbjct: 217 ELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEE 276
Query: 860 SGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKLE--SRSKDKKEKDE 917
++ ++ + Q E + + L+RE++ ++E ER ++ +E+ E R + ++E+ E
Sbjct: 277 QLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERRE 336
Query: 918 CTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKESSRSRSSHKDSPRD 977
R++ +RR + + ER E+ R ++ R + ++
Sbjct: 337 QQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLR 396
Query: 978 VSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRSHKKSKKNK 1028
++ +R R ++ RR + ++ ++ + + R + ++ ++ +
Sbjct: 397 REQQLRREQQ-LRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQR 446
Score = 55.1 bits (131), Expect = 3e-07
Identities = 51/273 (18%), Positives = 116/273 (42%), Gaps = 25/273 (9%)
Query: 778 KWELFDQHEESEEE-ENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEM 836
+W+ D+H EE+ E + Q+E + +Q K + + T+ KF + ++
Sbjct: 1285 RWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQL 1344
Query: 837 SEEKRAKLREIELKVMKFQDE-----------LESGKRPKKPGQSFQEQVEHYRDKLLQR 885
+E+ + + + KF++E LE +R ++ + + E + + +R
Sbjct: 1345 LQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQER 1404
Query: 886 EKEKELERERERDKKDKEKLESRSKDKK-EKDECTPTRKERKRRHSTSPSPSRSSSGRRV 944
E++ +R+R + ++++++L + +D+K ++E R+ER+R+ R R+
Sbjct: 1405 EQQLRQDRDR-KFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKF 1463
Query: 945 KSPSPKSERSERSERSHKESSRSRSSHKDSPR--DVSKKAKRSPSGSRTPKRS------- 995
+ + E + +E R + R + +K + S+ P+R
Sbjct: 1464 REEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQ 1523
Query: 996 --RRSRSRSPKKSGKKSRSQSRSPHRSHKKSKK 1026
R+ R R + ++ R Q R R + +K
Sbjct: 1524 LHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRK 1556
Score = 54.3 bits (129), Expect = 6e-07
Identities = 50/289 (17%), Positives = 123/289 (42%), Gaps = 25/289 (8%)
Query: 760 KWEAVDESELEAQAVTTSKWELFDQHEES---------------EEEENQNQEEESEDEE 804
+W+A ++SE Q ++ ++ L +Q E EEEE + + + + E
Sbjct: 770 QWQAEEKSERGRQRLS-ARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRERE 828
Query: 805 DTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLREIELKVMKFQDELESGKRP 864
EE L +++ E + + + + R + + ++E + +
Sbjct: 829 KELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHT 888
Query: 865 KKPGQSFQEQVEHYRDKLLQREKEKELER-ERERDKKDKEKLESRSKDKKEKDECTPTRK 923
+ QEQ+ +++ L +E+E+EL+R ERE+ ++ +++ + R +++ +++E R+
Sbjct: 889 LYAKPALQEQLR--KEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLRE 946
Query: 924 ER-KRRHSTSPSPSRSSSGRRVK-----SPSPKSERSERSERSHKESSRSRSSHKDSPRD 977
ER KRR R + K P+ R + E+ ++E + + R+
Sbjct: 947 EREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLRE 1006
Query: 978 VSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRSHKKSKK 1026
+K +R + K+ + ++ + + + R +++ ++
Sbjct: 1007 EREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEE 1055
Score = 52.0 bits (123), Expect = 3e-06
Identities = 57/284 (20%), Positives = 117/284 (41%), Gaps = 25/284 (8%)
Query: 748 KKNEPIFKVAPSKWEAVD---ESELEAQAVTTSKWELFDQHEESEEEENQNQEEESEDEE 804
+K E + + K + + + EL+ + K E + E +EEE Q Q E +
Sbjct: 247 RKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQ- 305
Query: 805 DTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLREIELKVMKFQDELESGKRP 864
K EE + E E + E EE+R + E + + Q +
Sbjct: 306 --LRRKQEEERREQQEERREQQERR-----EQQEERREQQLRREQEERREQQLRREQEEE 358
Query: 865 KKPGQSFQEQVEHYRDKLLQRE----KEKELERE----RERDKKDKEKLESRSKDKKEKD 916
++ Q +EQ E R++ L+RE +E++L RE RE+ + +++L + ++E+
Sbjct: 359 RREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 418
Query: 917 ---ECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKS--ERSERSERSHKESSRSRSSH 971
E R++ + RH R + + + +R E +ER H++ R +
Sbjct: 419 LRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETER-HEQERRKQQLK 477
Query: 972 KDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSR 1015
+D + ++ + R ++ RR + ++ ++ + R
Sbjct: 478 RDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKR 521
Score = 50.1 bits (118), Expect = 1e-05
Identities = 60/297 (20%), Positives = 132/297 (44%), Gaps = 39/297 (13%)
Query: 745 EDSKKNEPIFKVAPSKWEAVDESELEAQAVTTSKWELFDQHEESEEEENQNQEE------ 798
++ ++++ ++ P K AV ++++ + E F Q E+S+ + Q+Q++
Sbjct: 1216 DEDQRSDLKWQWEPEKENAVRDNKVYCKGREN---EQFRQLEDSQLRDRQSQQDLQHLLG 1272
Query: 799 ---ESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLREIELKVMK-- 853
E + E++ + + + H P +E++ E E+K AK R+ + + K
Sbjct: 1273 EQQERDREQERRRWQQRDRHF---PEEEQL---------EREEQKEAKRRDRKSQEEKQL 1320
Query: 854 FQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELER-ERERDKKDKEKLESRSKDK 912
++E E +R ++ + F+E+ ++LLQ +E+ L R ER+R +++E K
Sbjct: 1321 LREEREEKRRRQETDRKFREE-----EQLLQEREEQPLRRQERDRKFREEELRHQEQGRK 1375
Query: 913 KEKDECTPTRKERKRRHSTSPSPSR-SSSGRRVKSPSPKSERSERSERSHKESSRSRSSH 971
++E R+ER+R+ R ++++ + R E + S +E R
Sbjct: 1376 FLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREE 1435
Query: 972 KDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRSHKKSKKNK 1028
+ R + +R ++ R+ R R K ++ Q R + H++ + K
Sbjct: 1436 EQQVR----RQERERKFLEEEQQLRQERHR--KFREEEQLLQEREEQQLHRQERDRK 1486
Score = 48.5 bits (114), Expect = 3e-05
Identities = 56/266 (21%), Positives = 112/266 (42%), Gaps = 33/266 (12%)
Query: 789 EEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLREIE 848
EE++ + QE + +D EE L +++++ + + + EE++ + +E E
Sbjct: 1536 EEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRL-EEQKVRRQEQE 1594
Query: 849 LKVMKFQDELESGKRPKKPGQSFQEQVEHYR--DKLLQREKEKELERERERDKK------ 900
K M+ + +L +R + Q QE+ +R ++LLQ +E++L R+ ERD+K
Sbjct: 1595 RKFMEDEQQL---RRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQ-ERDRKFLEEEP 1650
Query: 901 -----DKEKLESRSKDKK---------EKDECTPTRKERKRRHSTSPSPSRSSSGRRVKS 946
++E+ +D+K E +E R+ER R+ R R
Sbjct: 1651 QLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFL 1710
Query: 947 PSPKSERSERSERSHKESSRSR-SSHKDSPRDVSKKAKRSPSGSRTPKRS-----RRSRS 1000
+ R + ER +E + R + ++ R + K P+R R+ R
Sbjct: 1711 QEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERD 1770
Query: 1001 RSPKKSGKKSRSQSRSPHRSHKKSKK 1026
R ++ + + + RS + +K
Sbjct: 1771 RKFREEEQLRQEREEQQLRSQESDRK 1796
Score = 47.4 bits (111), Expect = 7e-05
Identities = 53/281 (18%), Positives = 122/281 (43%), Gaps = 37/281 (13%)
Query: 780 ELFDQHEES----EEEENQNQEEESEDEEDTQSSKSEEHHLYSNP-----IKEEMTESKF 830
+L + EE +E + + +EEE +E + EE L +KEE
Sbjct: 1343 QLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQ 1402
Query: 831 SKYSEMSEEKRAKLREIELKVM------KFQDELESGKRPKKPGQSFQEQV----EHYR- 879
+ ++ +++ K RE E ++ KF++E + +R ++ + +E+ E +R
Sbjct: 1403 EREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRK 1462
Query: 880 ----DKLLQREKEKELERERERDKK---DKEKLESRSKDKKEKDECTPTRKERKRRHSTS 932
++LLQ +E++L R+ ERD+K ++++L + +D+K +++ +++ ++
Sbjct: 1463 FREEEQLLQEREEQQLHRQ-ERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEE 1521
Query: 933 PSPSRSSSGRRVKSPSPKSERSERSE-------RSHKESSRSRSSHKDSPRDVSKKAKRS 985
R R+ + R ER + R +E + R ++ + +S++ +
Sbjct: 1522 QQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREE--QQLSRQERDR 1579
Query: 986 PSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRSHKKSKK 1026
K R+ + R + ++ R Q ++ +K
Sbjct: 1580 KFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRK 1620
Score = 46.2 bits (108), Expect = 2e-04
Identities = 54/259 (20%), Positives = 111/259 (42%), Gaps = 29/259 (11%)
Query: 789 EEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMT-ESKFSKYSEMSEEKRAKLREI 847
EE + + QE E + D EE L ++++ + + K+ E EE++ + +E
Sbjct: 1648 EEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFRE--EEQQLRRQER 1705
Query: 848 ELKVMKFQDELESGKRPKK-------PGQSFQEQV---EHYRDKLLQREK---EKELERE 894
E K ++ + +L + +K ++ QEQ+ E YR K+L+ E+ E+E ++
Sbjct: 1706 ERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYR-KILEEEQLRPEREEQQL 1764
Query: 895 RERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERS 954
R +++ K + E + + ++E+ + +RK R R R + K
Sbjct: 1765 RRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWE 1824
Query: 955 ERSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQS 1014
E + ++ R R RD + R+ T ++SRR ++ +K R +
Sbjct: 1825 EEQLQLEEQEQRLRQE-----RD---RQYRAEEQFATQEKSRREEQELWQEEEQKRRQER 1876
Query: 1015 ----RSPHRSHKKSKKNKH 1029
R H ++ ++ +H
Sbjct: 1877 ERKLREEHIRRQQKEEQRH 1895
Score = 46.2 bits (108), Expect = 2e-04
Identities = 45/233 (19%), Positives = 102/233 (43%), Gaps = 23/233 (9%)
Query: 786 EESEEEENQNQEEESEDEEDTQSSKSEEHHLY----SNPIKEEMTESKFSKYSEMSEEKR 841
+E EE++ + QE + + E+ Q + +E ++ + E KF + ++ +E
Sbjct: 1677 QEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETE 1736
Query: 842 AKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKD 901
+ + + K +E + RP++ Q + Q RD+ + +E++L +ERE
Sbjct: 1737 QEQLRRQERYRKILEEEQL--RPEREEQQLRRQE---RDRKFR--EEEQLRQERE----- 1784
Query: 902 KEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSE---RSE 958
+++L S+ D+K ++E + R+ R P + R + + E E R E
Sbjct: 1785 EQQLRSQESDRKFREE----EQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQE 1840
Query: 959 RSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSR 1011
R + + + + ++ R ++ + R +R R+ R ++ K+ +
Sbjct: 1841 RDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQ 1893
Score = 45.4 bits (106), Expect = 3e-04
Identities = 35/188 (18%), Positives = 83/188 (44%), Gaps = 19/188 (10%)
Query: 789 EEEENQNQEEESEDEEDTQSSKSEEHHL----YSNPIKEEMTESKFSKYSEMSEEKRAKL 844
EE+ Q E+E ++ EE L ++ + + KF + ++ +E+ +
Sbjct: 1728 EEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQ 1787
Query: 845 REIELKVMKFQDELESGKRPKKPGQSFQEQVEHYR---DKLLQREKEKELERERERDKKD 901
+ KF++E + + ++ Q++ YR ++L E+E+ L +ER+R +
Sbjct: 1788 LRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRA 1847
Query: 902 KEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSH 961
+E+ ++ K ++E+ E ++++R+ R K R ++ E+ H
Sbjct: 1848 EEQFATQEKSRREEQELWQEEEQKRRQE------------RERKLREEHIRRQQKEEQRH 1895
Query: 962 KESSRSRS 969
++ +S
Sbjct: 1896 RQVGEIKS 1903
Score = 45.1 bits (105), Expect = 4e-04
Identities = 51/259 (19%), Positives = 110/259 (42%), Gaps = 34/259 (13%)
Query: 784 QHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSK----------Y 833
Q + + E + +E E+++ ++ + + L ++ + E KF +
Sbjct: 1551 QDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQ 1610
Query: 834 SEMSEEKRAKLREIE-LKVMKFQDELESGKR--------PKKPGQSFQEQVEHYRDK--- 881
++ +E+ K RE E L + + +L +R P+ Q ++Q+ H RD+
Sbjct: 1611 QQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFR 1670
Query: 882 ----LLQREKEKELERERERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSR 937
LLQ +E++L R+ ERD+K +E+ + + ++E+ ++E++ R R
Sbjct: 1671 EEEQLLQEGEEQQLRRQ-ERDRKFREEEQQLRRQERERKF---LQEEQQLRRQELERKFR 1726
Query: 938 SSSGRRVKSPSPKSERSERSER-SHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSR 996
R ++ + R ER + +E R + R + R R + +
Sbjct: 1727 EEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQ 1786
Query: 997 RSRSRSPKKSGKKSRSQSR 1015
+ RS ++S +K R + +
Sbjct: 1787 QLRS---QESDRKFREEEQ 1802
Score = 41.6 bits (96), Expect = 0.004
Identities = 29/155 (18%), Positives = 70/155 (45%), Gaps = 4/155 (2%)
Query: 787 ESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLRE 846
E EE++ + QE + + E+ Q + E ++ + ++ KF + ++ +E+ +
Sbjct: 1758 EREEQQLRRQERDRKFREEEQLRQEREEQ----QLRSQESDRKFREEEQLRQEREEQQLR 1813
Query: 847 IELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKLE 906
+ + K++ E E + ++ + QE+ YR + +EK E+E +++++K
Sbjct: 1814 PQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRR 1873
Query: 907 SRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSG 941
+ K ++ +KE +R S+ G
Sbjct: 1874 QERERKLREEHIRRQQKEEQRHRQVGEIKSQEGKG 1908
Score = 39.7 bits (91), Expect = 0.015
Identities = 45/244 (18%), Positives = 99/244 (40%), Gaps = 23/244 (9%)
Query: 786 EESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLR 845
+E EE++ QE + + E+ Q + +E +E+ S+ + + EE++ +
Sbjct: 1471 QEREEQQLHRQERDRKFLEEEQQLRRQER---DRKFREQELRSQEPERKFLEEEQQLHRQ 1527
Query: 846 EIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKL 905
+ + K ++ + +L +R ++ Q + +RE+++ +ER+R K +L
Sbjct: 1528 QRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDR----KFRL 1583
Query: 906 ESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSP-----KSERSERSERS 960
E + K ++++ E E++ R R R+ + + ++ R ER
Sbjct: 1584 EEQ-KVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERD 1642
Query: 961 HK---------ESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSR 1011
K R + D R ++ + G R R+ R R ++ ++ R
Sbjct: 1643 RKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLR-RQERDRKFREEEQQLR 1701
Query: 1012 SQSR 1015
Q R
Sbjct: 1702 RQER 1705
Score = 38.5 bits (88), Expect = 0.033
Identities = 27/152 (17%), Positives = 76/152 (50%), Gaps = 7/152 (4%)
Query: 765 DESELEAQAVTTSKWELFDQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEE 824
+E +L Q E +E EE++ ++QE + + E+ Q + E ++ +
Sbjct: 1760 EEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQERE----EQQLRPQ 1815
Query: 825 MTESKFSKYSE--MSEEKRAKLREIELKVMKFQDELESGKRPKKPGQS-FQEQVEHYRDK 881
+ K+ E EE+ +LR+ + + +++ + ++ ++ Q +QE+ + R +
Sbjct: 1816 QRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQE 1875
Query: 882 LLQREKEKELERERERDKKDKEKLESRSKDKK 913
++ +E+ + R+++ +++ ++ E +S++ K
Sbjct: 1876 RERKLREEHIRRQQKEEQRHRQVGEIKSQEGK 1907
Score = 35.8 bits (81), Expect = 0.21
Identities = 35/201 (17%), Positives = 81/201 (40%), Gaps = 11/201 (5%)
Query: 836 MSEEKRAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERER 895
+ EEKRA+ E + + E + + + Q +E + R K ++E+E+EL
Sbjct: 95 LDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQK--RQEQERELAEGE 152
Query: 896 ERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSE 955
E+ +K +E+LE R + +++++ ++ ++R + S P E+
Sbjct: 153 EQSEK-QERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLR 211
Query: 956 RSE--------RSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSG 1007
R E R K+ R + + K+ ++ + R + + ++
Sbjct: 212 RRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQREL 271
Query: 1008 KKSRSQSRSPHRSHKKSKKNK 1028
++ Q R R + ++ +
Sbjct: 272 QEEEEQLRKLERQELRRERQE 292
Score = 35.8 bits (81), Expect = 0.21
Identities = 39/204 (19%), Positives = 83/204 (40%), Gaps = 16/204 (7%)
Query: 827 ESKFSKYSEMSEEKRAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQRE 886
ES + +++R + R+ +L E E G+R + Q QEQ + Q E
Sbjct: 107 ESLLQDRRQEEDQRRFEPRDRQL-------EEEPGQRRR---QKRQEQERELAEGEEQSE 156
Query: 887 KEKELERERERDKKDKEKLESRSK-DKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVK 945
K++ LE +R+R ++D+E R + ++E+ + + + H T P RR
Sbjct: 157 KQERLE-QRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRREL 215
Query: 946 SPSPKSERSERSERSHKESSRSRSSHKDS---PRDVSKKAKRSPSGSRTPKRSRRSRSRS 1002
+ R E+ ++ + R ++ R+ + + P+R R +
Sbjct: 216 LELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEE 275
Query: 1003 PKKSGKKSRSQSRSPHRSHKKSKK 1026
++ K R + R + ++ ++
Sbjct: 276 -EQLRKLERQELRRERQEEEQQQQ 298
Score = 30.8 bits (68), Expect = 6.9
Identities = 44/194 (22%), Positives = 83/194 (42%), Gaps = 38/194 (19%)
Query: 69 HQNLSRPLLENKLKAFSIGKMSTAKRTLSKKEQEELKKKEDEKAAAEIYEEFLAAFEGSD 128
H ++P L+ +L+ ++ L ++E+EEL+++E EK + E E
Sbjct: 887 HTLYAKPALQEQLRK---------EQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQ 937
Query: 129 GNKVKTFVRGGVVNAAKEEHETDEKRGKIYKPSSRFADQKNPPNQSSNERPPSLLVIETK 188
+EE E+R K + +K+ Q E+ LL E +
Sbjct: 938 ---------------QEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQ---LLGEEPE 979
Query: 189 KPPLKKGEKEKK-KSNLELFKEELKQIQEERDER--------HKTKGRLSRFEPPQSDSD 239
K ++ E+EKK + EL +EE + ++EER++R ++ K L + E +
Sbjct: 980 KR--RRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREE 1037
Query: 240 GQRRSMDAPSRRNR 253
++R + R+ R
Sbjct: 1038 REKRRLQERERQYR 1051
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 [Homo
sapiens]
Length = 916
Score = 73.6 bits (179), Expect = 9e-13
Identities = 67/263 (25%), Positives = 118/263 (44%), Gaps = 21/263 (7%)
Query: 765 DESELEAQAVTTSKWELFDQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEE 824
++SE+E +A+T EL +E ++E + +EEE E EE+ ++K + +KEE
Sbjct: 465 EKSEME-EALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEE 523
Query: 825 MTESKFSKYSEMSEEKRAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQ 884
E + + E EE+ + D+ E G +K G S +E+ E Q
Sbjct: 524 EGEKEEEEGQEEEEEEDEGAK---------SDQAEEG-GSEKEGSSEKEEGE-------Q 566
Query: 885 REKEKELERE-RERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRR 943
E E E E E E + K+++K+E +S++ K+E K K + SP P +S +
Sbjct: 567 EEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVP-KSPVEEK 625
Query: 944 VKSPSPKSERSERSERSHKESSRSRSSHKDSPRD-VSKKAKRSPSGSRTPKRSRRSRSRS 1002
KSP PKS E+ + +S P+ V +K K S S ++++ +S
Sbjct: 626 GKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKS 685
Query: 1003 PKKSGKKSRSQSRSPHRSHKKSK 1025
P + K + + ++ +
Sbjct: 686 PVEEAKSKAEVGKGEQKEEEEKE 708
Score = 62.8 bits (151), Expect = 2e-09
Identities = 69/292 (23%), Positives = 117/292 (40%), Gaps = 36/292 (12%)
Query: 762 EAVDESELEAQAVTTSKWELFD-----QHEESEEEENQNQEEESEDEEDTQSSKSEEHHL 816
E +E E E + V K + + EE E+EE + QEEE E++E +S ++EE
Sbjct: 494 EKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGS 553
Query: 817 YSNPIKE------EMTESKFSKYSEMSEEKRAKLREIELKVMKFQDELESGKRPKKPGQS 870
E E E++ E +E K K E + + + ++EL + + +KP
Sbjct: 554 EKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKP--- 610
Query: 871 FQEQVEHYRDKLLQREKEKELERERERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHS 930
E+ + K EK K + ++K K + ++K K + E K +
Sbjct: 611 --EKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSP 668
Query: 931 TSPSPSRSSSGRRVKSPSPKS--------------ERSERSERSHKESSRSRSSHK--DS 974
S SP + KSP PKS E+ E E+ KE+ + K +
Sbjct: 669 VSKSPVE----EKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEK 724
Query: 975 PRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRSHKKSKK 1026
P+DV +K K + ++S K +K + P + K+ +K
Sbjct: 725 PKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEK 776
Score = 40.4 bits (93), Expect = 0.009
Identities = 65/285 (22%), Positives = 112/285 (39%), Gaps = 28/285 (9%)
Query: 683 EEKETEDVPDDLDGAPIEEELDGAPLEDVDGI--PIDATPIDDLDGVPIKSLDDDLDGVP 740
EEK+ E+ +++ A EE + A +E + P+ +P+++ P VP
Sbjct: 584 EEKKVEEKSEEV--ATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSP----------VP 631
Query: 741 LDATEDSKKNE-PIFKVAPSKWEAVDESELEAQAVTTSKWELFDQHEESEEEENQNQEEE 799
E+ K+ P V V +S +E + + ++ +S ++ +E +
Sbjct: 632 KSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAK 691
Query: 800 SEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLREIELKVMKFQDELE 859
S+ E K EE KEE E K K ++ E+K+A+ E V + +
Sbjct: 692 SKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITK 751
Query: 860 SGKRPKKPGQSFQEQVEHYRDKLLQREKEKEL---ERERERDKKDKEKLESRSKD---KK 913
S K E+ K LQ+EKEKE E E + DK SR +D
Sbjct: 752 SVK-------VHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNG 804
Query: 914 EKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSE 958
E + +E K + S + SP+ + + ++SE
Sbjct: 805 EVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSE 849
Score = 34.7 bits (78), Expect = 0.48
Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 7/110 (6%)
Query: 98 KKEQEELKKKEDEKAAAEIYEEFLAAFEGSDGNKVKTFVRG-------GVVNAAKEEHET 150
++E +E +++EDE A ++ EE + EGS + G G AKEE +
Sbjct: 529 EEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKV 588
Query: 151 DEKRGKIYKPSSRFADQKNPPNQSSNERPPSLLVIETKKPPLKKGEKEKK 200
+EK ++ AD K + + P V E K P+ K E+K
Sbjct: 589 EEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEK 638
Score = 34.7 bits (78), Expect = 0.48
Identities = 37/154 (24%), Positives = 67/154 (43%), Gaps = 9/154 (5%)
Query: 100 EQEELKKKEDEKAAAEIYEEFLAAFEGSDGNKVKTFVRGGVVNAAKEE---HETDEKRGK 156
E +E KK E++ EE +A + K K+ V V + E++GK
Sbjct: 581 EAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGK 640
Query: 157 IYKPSSRFADQ-KNP----PNQSSNERPPSLLVIETK-KPPLKKGEKEKKKSNLELFKEE 210
P S ++ K+P P + + P S +E K K P+ K E+ KS E+ K E
Sbjct: 641 SPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGE 700
Query: 211 LKQIQEERDERHKTKGRLSRFEPPQSDSDGQRRS 244
K+ +E+ + + ++ + E D ++++
Sbjct: 701 QKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKA 734
Score = 33.5 bits (75), Expect = 1.1
Identities = 33/134 (24%), Positives = 53/134 (39%), Gaps = 19/134 (14%)
Query: 91 TAKRTLSKKEQEELKKKEDEKAAAEIYEEFLAAFEGSDGNKVKTFVRGGVVNAAKEEHET 150
T + K + E K K K EI EE E S+ + T + + + KEE +
Sbjct: 431 TISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKK- 489
Query: 151 DEKRGKIYKPSSRFADQKNPPNQSSNERPPSLLVIETKKPPLKKGEKEKKKSNLELFKEE 210
A++K ++ E + KK P+K E K+ E +EE
Sbjct: 490 ------------EAAEEKEEEPEAEEEE------VAAKKSPVKATAPEVKEEEGEKEEEE 531
Query: 211 LKQIQEERDERHKT 224
++ +EE DE K+
Sbjct: 532 GQEEEEEEDEGAKS 545
Score = 32.3 bits (72), Expect = 2.4
Identities = 36/149 (24%), Positives = 59/149 (39%), Gaps = 10/149 (6%)
Query: 10 QKASSKTRSSDVHSSGSSDAHMDASGPSDSDMPSRTRPKSPRKHNYRNESARESLCDSPH 69
+KA S S V + S + + + PK + E E D P
Sbjct: 676 EKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKV-----EKKEEKPKDVPE 730
Query: 70 QNLSRPLLENKLKAFSIGKMSTAKRTLSKKEQEELK----KKEDEKAAAEIYEEFLAAFE 125
+ + ++ + A + + K L K+ +EE K +KE EKA E E + +
Sbjct: 731 KKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDK 790
Query: 126 GSDGNKVKTFVRGGVVNAAKE-EHETDEK 153
G+ G++ + G V +E E ET EK
Sbjct: 791 GAKGSRKEDIAVNGEVEGKEEVEQETKEK 819
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 [Homo
sapiens]
Length = 540
Score = 73.6 bits (179), Expect = 9e-13
Identities = 67/263 (25%), Positives = 118/263 (44%), Gaps = 21/263 (7%)
Query: 765 DESELEAQAVTTSKWELFDQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEE 824
++SE+E +A+T EL +E ++E + +EEE E EE+ ++K + +KEE
Sbjct: 89 EKSEME-EALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEE 147
Query: 825 MTESKFSKYSEMSEEKRAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQ 884
E + + E EE+ + D+ E G +K G S +E+ E Q
Sbjct: 148 EGEKEEEEGQEEEEEEDEGAK---------SDQAEEG-GSEKEGSSEKEEGE-------Q 190
Query: 885 REKEKELERE-RERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRR 943
E E E E E E + K+++K+E +S++ K+E K K + SP P +S +
Sbjct: 191 EEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVP-KSPVEEK 249
Query: 944 VKSPSPKSERSERSERSHKESSRSRSSHKDSPRD-VSKKAKRSPSGSRTPKRSRRSRSRS 1002
KSP PKS E+ + +S P+ V +K K S S ++++ +S
Sbjct: 250 GKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKS 309
Query: 1003 PKKSGKKSRSQSRSPHRSHKKSK 1025
P + K + + ++ +
Sbjct: 310 PVEEAKSKAEVGKGEQKEEEEKE 332
Score = 62.8 bits (151), Expect = 2e-09
Identities = 69/292 (23%), Positives = 117/292 (40%), Gaps = 36/292 (12%)
Query: 762 EAVDESELEAQAVTTSKWELFD-----QHEESEEEENQNQEEESEDEEDTQSSKSEEHHL 816
E +E E E + V K + + EE E+EE + QEEE E++E +S ++EE
Sbjct: 118 EKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGS 177
Query: 817 YSNPIKE------EMTESKFSKYSEMSEEKRAKLREIELKVMKFQDELESGKRPKKPGQS 870
E E E++ E +E K K E + + + ++EL + + +KP
Sbjct: 178 EKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKP--- 234
Query: 871 FQEQVEHYRDKLLQREKEKELERERERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHS 930
E+ + K EK K + ++K K + ++K K + E K +
Sbjct: 235 --EKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSP 292
Query: 931 TSPSPSRSSSGRRVKSPSPKS--------------ERSERSERSHKESSRSRSSHK--DS 974
S SP + KSP PKS E+ E E+ KE+ + K +
Sbjct: 293 VSKSPVE----EKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEK 348
Query: 975 PRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRSHKKSKK 1026
P+DV +K K + ++S K +K + P + K+ +K
Sbjct: 349 PKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEK 400
Score = 40.4 bits (93), Expect = 0.009
Identities = 65/285 (22%), Positives = 112/285 (39%), Gaps = 28/285 (9%)
Query: 683 EEKETEDVPDDLDGAPIEEELDGAPLEDVDGI--PIDATPIDDLDGVPIKSLDDDLDGVP 740
EEK+ E+ +++ A EE + A +E + P+ +P+++ P VP
Sbjct: 208 EEKKVEEKSEEV--ATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSP----------VP 255
Query: 741 LDATEDSKKNE-PIFKVAPSKWEAVDESELEAQAVTTSKWELFDQHEESEEEENQNQEEE 799
E+ K+ P V V +S +E + + ++ +S ++ +E +
Sbjct: 256 KSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAK 315
Query: 800 SEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLREIELKVMKFQDELE 859
S+ E K EE KEE E K K ++ E+K+A+ E V + +
Sbjct: 316 SKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITK 375
Query: 860 SGKRPKKPGQSFQEQVEHYRDKLLQREKEKEL---ERERERDKKDKEKLESRSKD---KK 913
S K E+ K LQ+EKEKE E E + DK SR +D
Sbjct: 376 SVK-------VHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNG 428
Query: 914 EKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSE 958
E + +E K + S + SP+ + + ++SE
Sbjct: 429 EVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSE 473
Score = 34.7 bits (78), Expect = 0.48
Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 7/110 (6%)
Query: 98 KKEQEELKKKEDEKAAAEIYEEFLAAFEGSDGNKVKTFVRG-------GVVNAAKEEHET 150
++E +E +++EDE A ++ EE + EGS + G G AKEE +
Sbjct: 153 EEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKV 212
Query: 151 DEKRGKIYKPSSRFADQKNPPNQSSNERPPSLLVIETKKPPLKKGEKEKK 200
+EK ++ AD K + + P V E K P+ K E+K
Sbjct: 213 EEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEK 262
Score = 34.7 bits (78), Expect = 0.48
Identities = 37/154 (24%), Positives = 67/154 (43%), Gaps = 9/154 (5%)
Query: 100 EQEELKKKEDEKAAAEIYEEFLAAFEGSDGNKVKTFVRGGVVNAAKEE---HETDEKRGK 156
E +E KK E++ EE +A + K K+ V V + E++GK
Sbjct: 205 EAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGK 264
Query: 157 IYKPSSRFADQ-KNP----PNQSSNERPPSLLVIETK-KPPLKKGEKEKKKSNLELFKEE 210
P S ++ K+P P + + P S +E K K P+ K E+ KS E+ K E
Sbjct: 265 SPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGE 324
Query: 211 LKQIQEERDERHKTKGRLSRFEPPQSDSDGQRRS 244
K+ +E+ + + ++ + E D ++++
Sbjct: 325 QKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKA 358
Score = 33.5 bits (75), Expect = 1.1
Identities = 33/134 (24%), Positives = 53/134 (39%), Gaps = 19/134 (14%)
Query: 91 TAKRTLSKKEQEELKKKEDEKAAAEIYEEFLAAFEGSDGNKVKTFVRGGVVNAAKEEHET 150
T + K + E K K K EI EE E S+ + T + + + KEE +
Sbjct: 55 TISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKK- 113
Query: 151 DEKRGKIYKPSSRFADQKNPPNQSSNERPPSLLVIETKKPPLKKGEKEKKKSNLELFKEE 210
A++K ++ E + KK P+K E K+ E +EE
Sbjct: 114 ------------EAAEEKEEEPEAEEEE------VAAKKSPVKATAPEVKEEEGEKEEEE 155
Query: 211 LKQIQEERDERHKT 224
++ +EE DE K+
Sbjct: 156 GQEEEEEEDEGAKS 169
Score = 32.3 bits (72), Expect = 2.4
Identities = 36/149 (24%), Positives = 59/149 (39%), Gaps = 10/149 (6%)
Query: 10 QKASSKTRSSDVHSSGSSDAHMDASGPSDSDMPSRTRPKSPRKHNYRNESARESLCDSPH 69
+KA S S V + S + + + PK + E E D P
Sbjct: 300 EKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKV-----EKKEEKPKDVPE 354
Query: 70 QNLSRPLLENKLKAFSIGKMSTAKRTLSKKEQEELK----KKEDEKAAAEIYEEFLAAFE 125
+ + ++ + A + + K L K+ +EE K +KE EKA E E + +
Sbjct: 355 KKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDK 414
Query: 126 GSDGNKVKTFVRGGVVNAAKE-EHETDEK 153
G+ G++ + G V +E E ET EK
Sbjct: 415 GAKGSRKEDIAVNGEVEGKEEVEQETKEK 443
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 73.6 bits (179), Expect = 9e-13
Identities = 51/249 (20%), Positives = 107/249 (42%), Gaps = 7/249 (2%)
Query: 783 DQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRA 842
DQ +S E + + ++ E Q S H N E + + + + +
Sbjct: 615 DQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDE 674
Query: 843 KLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKK-D 901
+ RE + + + ++ +R + + + ++E R + +RE+EKE +RER+RD+ D
Sbjct: 675 RARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHD 734
Query: 902 KEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSH 961
+E+ R +D++++ E +ER+R R R + + ER +R
Sbjct: 735 RERERERERDREKEREREREERERERERERERERERERERERARERDKERER----QRDW 790
Query: 962 KESSRSRSSHKDSPRDV--SKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHR 1019
++ + R ++ ++ + + ++ KR R S SP++S K+ R S
Sbjct: 791 EDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDA 850
Query: 1020 SHKKSKKNK 1028
+ KN+
Sbjct: 851 YNSGDDKNE 859
Score = 67.4 bits (163), Expect = 7e-11
Identities = 62/259 (23%), Positives = 109/259 (42%), Gaps = 20/259 (7%)
Query: 779 WELFDQHEESE---EEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSE 835
WE + E + E +N++Q +S E + E N +++ S
Sbjct: 596 WETRSSYPERDRYPERDNRDQARDSSFER-----RHGERDRRDNRERDQRPSSPIRHQGR 650
Query: 836 MSEEKRAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERER 895
E +R + RE E +V + D + R + + + E R++ RE+EKE E ER
Sbjct: 651 NDELERDERRE-ERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELER 709
Query: 896 ERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSE 955
ER +++E+ + +D +E+D +ER+R R + + E
Sbjct: 710 ER-AREREREREKERD-RERDRDRDHDRERERERERDREKEREREREERERERERERERE 767
Query: 956 RSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSP------KKSGKK 1009
R +E +R R ++ RD K K R KR R+P +KS K+
Sbjct: 768 RERERERERARERDKERERQRDWEDKDK--GRDDRREKREEIREDRNPRDGHDERKSKKR 825
Query: 1010 SRSQ-SRSPHRSHKKSKKN 1027
R++ S SP +S K+ +++
Sbjct: 826 YRNEGSPSPRQSPKRRREH 844
Score = 67.4 bits (163), Expect = 7e-11
Identities = 67/286 (23%), Positives = 123/286 (43%), Gaps = 43/286 (15%)
Query: 783 DQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEK-- 840
++ E + E +++E E E E + + +E L +E E + + E ++
Sbjct: 674 ERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDH 733
Query: 841 -RAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDK 899
R + RE E K + E E +R ++ + + + E R++ RE++KE ER+R+ +
Sbjct: 734 DRERERERERDREK-EREREREERERERERERERERERERERERARERDKERERQRDWED 792
Query: 900 KDKEKLESRSKDKKEKDECTPT-----RKERKR-RHSTSPSPSRSSSGRRVKSPSPKSER 953
KDK + + R K ++ +++ P RK +KR R+ SPSP +S RR SP +
Sbjct: 793 KDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYN 852
Query: 954 S--ERSERSHKESS--RSRSSHKDSPRDVS-------KKAKRSPSGSRTPKRSRRSRSRS 1002
S +++E+ S R + S SP ++ K+ R P + +R +
Sbjct: 853 SGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKE 912
Query: 1003 PKKSGKKSRSQSR----------------------SPHRSHKKSKK 1026
S K R Q+ + R+H ++KK
Sbjct: 913 KVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKK 958
Score = 65.1 bits (157), Expect = 3e-10
Identities = 51/248 (20%), Positives = 106/248 (42%), Gaps = 18/248 (7%)
Query: 792 ENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLREIE--- 848
++ + D +T+SS E +++ +S F + E R RE +
Sbjct: 584 DSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFER--RHGERDRRDNRERDQRP 641
Query: 849 ---LKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDK-KDKEK 904
++ DELE +R ++ + R + RE+E++ ERERER++ +D+E+
Sbjct: 642 SSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDRER 701
Query: 905 LESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKES 964
+ R +++ E +ER+R R R + + +R + ER +E
Sbjct: 702 EKERELERERARE-----REREREKERDRERDRDRDHDRERERERERDREKEREREREER 756
Query: 965 SRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSR----RSRSRSPKKSGKKSRSQSRSPHRS 1020
R R ++ R+ ++ +R+ + +R R + + R ++ ++ + R+P
Sbjct: 757 ERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDG 816
Query: 1021 HKKSKKNK 1028
H + K K
Sbjct: 817 HDERKSKK 824
Score = 53.5 bits (127), Expect = 1e-06
Identities = 65/273 (23%), Positives = 107/273 (39%), Gaps = 38/273 (13%)
Query: 790 EEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLREI-- 847
E+EN + EE +++ S + L +P + ++S K S S K R+
Sbjct: 181 EQENMEKREEIIIKKEV-SPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSA 239
Query: 848 -------ELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKK 900
+ + K + G R P E + + K ++ K K+ E+ RD K
Sbjct: 240 VSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGK-KYKEKYKVKDRIEEKTRDGK 298
Query: 901 DKEKLESRSKDKKEKDECTPTRKER----KRRHSTSPSPSRSS------SGRRVKSPSPK 950
D+ + R ++K++K T + RH +S S S SS S RR ++PSP
Sbjct: 299 DRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPS 358
Query: 951 SERS-----ERSERSHKESSRSRSSHKDSP-------RDVSKKAKRSPSGSRTPKRSRRS 998
+R+ RS + S S K SP R+ + S S + RR
Sbjct: 359 YQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERRE 418
Query: 999 RSRSPKKSGKKSR-----SQSRSPHRSHKKSKK 1026
+R + K SR Q +S R H+ ++
Sbjct: 419 DTRGKRDREKDSREEREYEQDQSSSRDHRDDRE 451
Score = 51.6 bits (122), Expect = 4e-06
Identities = 69/285 (24%), Positives = 114/285 (40%), Gaps = 63/285 (22%)
Query: 786 EESEEEENQNQE-EESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKL 844
E + E E +N E E + D+ D + H S +K + + + K + + EKR ++
Sbjct: 132 ERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKREEI 191
Query: 845 ---REIELKVMK--------FQDELESGKRPKKPGQSFQEQ------------VEHYRDK 881
+E+ +V++ + +S KR P S + ++ R+
Sbjct: 192 IIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNS 251
Query: 882 LLQREKEK---------------ELERERERDKKDKEKLESRSKDKKEKD-ECTPTRKER 925
+ K+K L ++ + K K+++E +++D K++ + R++R
Sbjct: 252 KTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKR 311
Query: 926 KRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKESSRSRSS---HKDSPRDVSKKA 982
+ STSP+ S S R H SS+S SS H SPR +K
Sbjct: 312 DKPRSTSPA---------------GQHHSPISSRHHSSSSQSGSSIQRHSPSPR---RKR 353
Query: 983 KRSPSGSRT-PKRSRRSRSRSPKKS-GKKSRSQSRSPHRSHKKSK 1025
SPS RT RRS S P S R QS HRS + K
Sbjct: 354 TPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREK 398
Score = 50.8 bits (120), Expect = 6e-06
Identities = 38/167 (22%), Positives = 72/167 (43%), Gaps = 6/167 (3%)
Query: 865 KKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKLE---SRSKDKKEKDECTPT 921
++ G+ E+ D+ +R ++ +R+RE+D +++ + E S S+D ++ E
Sbjct: 396 REKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDG 455
Query: 922 RKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKESSRSRSSHK---DSPRDV 978
R R R + R S R R + R ++S +R +H RD
Sbjct: 456 RDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDT 515
Query: 979 SKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRSHKKSK 1025
+K P SR+ R+ S + +SR++SRS R+ + +
Sbjct: 516 HRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGR 562
Score = 47.4 bits (111), Expect = 7e-05
Identities = 48/191 (25%), Positives = 75/191 (39%), Gaps = 27/191 (14%)
Query: 865 KKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKLESRS----KDKKEKDECTP 920
++ QS + E D +R++EK+ ERE ++ + R +D +++ +
Sbjct: 404 ERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARD 463
Query: 921 TRKERKRRHSTSPSPSRSS---SGRRVKSPSPKSERSERS-----ERSHKESSRSRSSHK 972
TR R+ R S SR S +S P+ RS R +R +++ R ++
Sbjct: 464 TRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYP 523
Query: 973 DSPRDVSKKAKRSPSG-------SRTPKRSR-------RSRSRSPKKSGKKSRSQSRSPH 1018
+ R + R S SR RS RSR R P+ K SR S
Sbjct: 524 EESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQI 583
Query: 1019 RSHKKSKKNKH 1029
SH S N H
Sbjct: 584 DSH-SSNSNYH 593
Score = 42.7 bits (99), Expect = 0.002
Identities = 52/250 (20%), Positives = 92/250 (36%), Gaps = 50/250 (20%)
Query: 824 EMTESKFSKYSEMSEEKRAKL-REIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKL 882
E T + E E+ R K RE + + + ++ +S R + + ++ RD+
Sbjct: 404 ERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDG----RDRR 459
Query: 883 LQREKEKELERERERDKKDKEKLESRSKDKKEKDECTPTRKERK-------------RRH 929
R+ E RD +D ++ S+D KE + +R R R+
Sbjct: 460 DARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKE 519
Query: 930 STSPSPSRSSSGRRVKSPSPKSE------RSERSERSHKESSRSRSSHKDSPRDVSKKAK 983
T P SRS ++ S ++E RSE + RSR + P S+ ++
Sbjct: 520 DTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSR 579
Query: 984 RS---------------------PSGSRTPKRSRRSRSRS---PKKSGKKSRSQSRSPHR 1019
S P R P+R R ++R ++ G++ R +R R
Sbjct: 580 GSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNR--ER 637
Query: 1020 SHKKSKKNKH 1029
+ S +H
Sbjct: 638 DQRPSSPIRH 647
Score = 35.4 bits (80), Expect = 0.28
Identities = 37/162 (22%), Positives = 76/162 (46%), Gaps = 24/162 (14%)
Query: 778 KWELFDQHEESEEEENQNQEEE------SEDEEDTQSSKSEEHHLYSNPI--KEEMTESK 829
+W+ D+ E +E + +E+E S D++ Q+ E + + I + + +
Sbjct: 888 RWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRE 947
Query: 830 FSKYSEMSEEKRAKLREIELKVMKFQDE-LESG--KRPKKPGQSFQEQVEHYRDKLLQRE 886
S + +K+AK+++ +K K D +E G + + GQ F + + +
Sbjct: 948 TSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPK---------KGQ 998
Query: 887 KEKELERERERDKKDKE--KLESRSKDKKEKDECTP--TRKE 924
K+K +E++R++ K D + E+ + KK++ TP T KE
Sbjct: 999 KKKSIEKKRKKSKGDSDISDEEAAQQSKKKRGPRTPPITTKE 1040
Score = 34.7 bits (78), Expect = 0.48
Identities = 36/142 (25%), Positives = 60/142 (42%), Gaps = 11/142 (7%)
Query: 881 KLLQREKEKELERERERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSS 940
K + +++ L R +L S S D + + ++R HS S ++ S
Sbjct: 1182 KPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVL-HSGSRDREKTKS 1240
Query: 941 ----GRRVKSPSPKSERSE--RSERSHKESSRSRSSHKDSP---RDVSKKAKRSPSGSRT 991
G R KS + +R E RS S ++ SRS SS + SP R V ++ S R
Sbjct: 1241 LEITGER-KSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRL 1299
Query: 992 PKRSRRSRSRSPKKSGKKSRSQ 1013
+R R R ++ + +R +
Sbjct: 1300 QERDRYEHDRERERERRDTRQR 1321
Score = 34.3 bits (77), Expect = 0.62
Identities = 38/169 (22%), Positives = 67/169 (39%), Gaps = 38/169 (22%)
Query: 884 QREKEKELERERERDKKDKEKLESRSKDKKEKDECTPTRKERKR-RHSTSPSPSRSSSGR 942
+R E+ RER K ++ +++ + + ++ +P RKE R RH +
Sbjct: 75 RRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRH------REKEDIK 128
Query: 943 RVKSPSPKSERSERSERSHKESSRSRSSHKDSPRDVSKKAKR------------------ 984
K +P+SE ++++ S + + D ++S + KR
Sbjct: 129 ITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKR 188
Query: 985 ---------SPSGSR---TPKRSRRSRSRSPK-KSGKKSRSQSRSPHRS 1020
SP R +P S R S+SPK KS KS S S+ ++
Sbjct: 189 EEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKT 237
Score = 34.3 bits (77), Expect = 0.62
Identities = 43/240 (17%), Positives = 87/240 (36%), Gaps = 34/240 (14%)
Query: 777 SKWELFDQHEESEEEENQNQEEESEDEEDTQSS--KSEEHHLYSNPIKEEMTESKFSKYS 834
SK ++ S + + + E S D + S K+E+H L S ++ + ES+ S
Sbjct: 822 SKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQ--ESRSLSPS 879
Query: 835 EMSEEKRAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERE 894
++E+++ + +E + ++P++ S +R +E+EL+ +
Sbjct: 880 HLTEDRQGRWKEED-------------RKPERKESS-------------RRYEEQELKEK 913
Query: 895 RERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERS 954
K +E+ E + + + R S + K P K +
Sbjct: 914 VSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKED 973
Query: 955 ERSERSHKESSRSRSSHKDSPRDVSKK----AKRSPSGSRTPKRSRRSRSRSPKKSGKKS 1010
+ + S SP+ KK KR S + + +S KK G ++
Sbjct: 974 DVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQQSKKKRGPRT 1033
Score = 32.7 bits (73), Expect = 1.8
Identities = 54/254 (21%), Positives = 103/254 (40%), Gaps = 27/254 (10%)
Query: 10 QKASSKTRSSDVHSSGSSDAHMDASGPSDSDMPSRTRPKSPRKHNYRNESARESLCDSPH 69
QK +++ SS V S H + D + P+S + N E+ R+ DS +
Sbjct: 101 QKRNTEESSSPVRKESSRGRHREKE---DIKITKERTPES-EEENVEWETNRD---DSDN 153
Query: 70 QNLSRPLLENKLKAFSIGKMSTAKRTLSKKEQEELKKKEDEKAAAEIYEEFLAAFEGSDG 129
+++ + K +R L K EQE ++K+E+ E+ E + + + S
Sbjct: 154 GDINYDYVHELSLEM---KRQKIQRELMKLEQENMEKREEIIIKKEVSPEVVRS-KLSPS 209
Query: 130 NKVKTFVRGGVVNAAKEEHETDEKRGKIYKPSSRFADQK--NPPNQSSNERPPSLLVIET 187
++ + ++ + +K K SS DQ+ + NQS + P T
Sbjct: 210 PSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGP------RT 263
Query: 188 KKPP------LKKGEKEKKKSNLELFKEELKQIQEERDERHKTKGRLSRFEPPQSDSDGQ 241
PP + G+K K+K ++ EE + ++ +D + + + + P+S S
Sbjct: 264 PSPPPPIPEDIALGKKYKEKYKVKDRIEE--KTRDGKDRGRDFERQREKRDKPRSTSPAG 321
Query: 242 RRSMDAPSRRNRSS 255
+ SR + SS
Sbjct: 322 QHHSPISSRHHSSS 335
Score = 32.7 bits (73), Expect = 1.8
Identities = 35/170 (20%), Positives = 76/170 (44%), Gaps = 23/170 (13%)
Query: 765 DESELEAQAVTTSKWELFDQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEE 824
D + ++ +T + DQ + E + S D +D++S S S+P +
Sbjct: 1234 DREKTKSLEITGERKSRIDQLKRGEPSRST-----SSDRQDSRSHSSRR----SSPESDR 1284
Query: 825 MTESKFSKYSEMSEEKRAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQ 884
S+ + + R +L+E + +++ + E R ++ + Q + + DK
Sbjct: 1285 QVHSRSGSF-----DSRDRLQERD----RYEHDRE---RERERRDTRQREWDRDADKDWP 1332
Query: 885 REKEKELERERERDK-KDKEKLESRSKDKKEKDECTPTR-KERKRRHSTS 932
R ++++ RERER++ +DK + R +++ D R ++R R +S
Sbjct: 1333 RNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFESS 1382
Score = 32.3 bits (72), Expect = 2.4
Identities = 34/126 (26%), Positives = 52/126 (41%), Gaps = 11/126 (8%)
Query: 903 EKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHK 962
EK+E+ ++ P ++R ++ S +SGR SP ++ + RS
Sbjct: 1166 EKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGR---LRSPSNDSAHRS--GDD 1220
Query: 963 ESSRSRSSHKDSPRDVSKKAKRSPSGSRTP-----KRSRRSRSRSPKKSGKKSRSQSRSP 1017
+S R R H S RD K +G R KR SRS S + +S S RS
Sbjct: 1221 QSGRKRVLHSGS-RDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSS 1279
Query: 1018 HRSHKK 1023
S ++
Sbjct: 1280 PESDRQ 1285
Score = 31.2 bits (69), Expect = 5.3
Identities = 50/268 (18%), Positives = 104/268 (38%), Gaps = 19/268 (7%)
Query: 4 KTPGGSQKASSKTRSSDVHSSGSSDAHMDASGPSDSDMPSRTRPKSPRKHNYRNESARES 63
+ P +K S +R S + S S+ + D S + S P R R P + N + AR+S
Sbjct: 566 RVPELPEKGSRGSRGSQIDSHSSNSNYHD-SWETRSSYPERDR--YPERDN--RDQARDS 620
Query: 64 LCDSPHQNLSRPLLENKLKAFSIGKMSTAKRTLSKKEQEELKKKEDEKAAAEIYEEFLAA 123
+ H R +N+ + + S+ R + ++ E ++ +E+ + +
Sbjct: 621 SFERRHGERDRR--DNRERD---QRPSSPIRHQGRNDELERDERREERRVDRVDDRRDER 675
Query: 124 FEGSDGNKVKTFVRGGVVNAAKEEHETDEKRGKIYKPSSRFADQKNPPNQSSNERPPSL- 182
D + + R + E E D +R K + A ++ + +R
Sbjct: 676 ARERDRERERDRER-----ERERERERDREREKERELERERAREREREREKERDRERDRD 730
Query: 183 --LVIETKKPPLKKGEKEKKKSNLELFKEELKQIQEERDERHKTKGRLSRFEPPQSDSDG 240
E ++ + EKE+++ E +E ++ + ER+ + + R + + D
Sbjct: 731 RDHDRERERERERDREKEREREREERERERERERERERERERERERARERDKERERQRDW 790
Query: 241 QRRSMDAPSRRNRSSGVLDDYAP-GSHD 267
+ + RR + + +D P HD
Sbjct: 791 EDKDKGRDDRREKREEIREDRNPRDGHD 818
>gi|125656165 THO complex 2 [Homo sapiens]
Length = 1593
Score = 73.2 bits (178), Expect = 1e-12
Identities = 79/337 (23%), Positives = 146/337 (43%), Gaps = 58/337 (17%)
Query: 747 SKKNEPIFKVAPSKWEAVDESELEAQAVTTSKWELFDQH-EESEEEENQNQEEESED--E 803
S N+ + + K + ++ + E TT + + + +E +EE N++E++ + E
Sbjct: 1260 SNSNKAVKENDKEKGKEKEKEKKEKTPATTPEARVLGKDGKEKPKEERPNKDEKARETKE 1319
Query: 804 EDTQSSKSEEHHLYSNPIKEEMTESKF----SKYSEMSEEKRAKLREIEL-KVMKFQDEL 858
+S K +E K+E ++ SK ++ E ++ RE ++ K MK ++ +
Sbjct: 1320 RTPKSDKEKEKFKKEEKAKDEKFKTTVPNAESKSTQEREREKEPSRERDIAKEMKSKENV 1379
Query: 859 ESGKR----------------PKKPGQSFQEQVEHY---------RDKLLQ-REKEKEL- 891
+ G++ P+ + + +++ + +D L++ +E +L
Sbjct: 1380 KGGEKTPVSGSLKSPVPRSDIPEPEREQKRRKIDTHPSPSHSSTVKDSLIELKESSAKLY 1439
Query: 892 ----------ERERERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSG 941
+ERE DKKD +K RS+++++KDE RKERKR HS +
Sbjct: 1440 INHTPPPLSKSKEREMDKKDLDKSRERSREREKKDE--KDRKERKRDHSNNDREVPPDLT 1497
Query: 942 RRVKSPS-------PKSE---RSERSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRT 991
+R K + KSE S KE ++S+SS K+ D K K S
Sbjct: 1498 KRRKEENGTMGVSKHKSESPCESPYPNEKDKEKNKSKSSGKEKGSDSFKSEKMDKISSGG 1557
Query: 992 PKRSRRSRSRSPKKSGKKSRSQSRSPHRSHKKSKKNK 1028
K SR + + KK K+ S + + HK S K++
Sbjct: 1558 KKESRHDKEKIEKKE-KRDSSGGKEEKKHHKSSDKHR 1593
Score = 45.8 bits (107), Expect = 2e-04
Identities = 50/212 (23%), Positives = 86/212 (40%), Gaps = 17/212 (8%)
Query: 831 SKYSEMSEEKRAKLREIELKVMKFQDELESG--KRPKKPGQSFQEQVEHYRDKLLQREKE 888
SK E S E+ K RE +K ++ S K G S + ++ ++ KE
Sbjct: 1217 SKSDESSTEETDKSRERSQCGVKAVNKASSTTPKGNSSNGNSGSNSNKAVKENDKEKGKE 1276
Query: 889 KELERERE------------RDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPS 936
KE E++ + +D K+K K E +KD+K ++ T K K +
Sbjct: 1277 KEKEKKEKTPATTPEARVLGKDGKEKPKEERPNKDEKARETKERTPKSDKEKEKFKKEEK 1336
Query: 937 RSSSGRRVKSPSPKSERSERSERSHKESSRSRSSHKD-SPRDVSKKAKRSPSGSRTPKRS 995
+ P+ +S+ ++ ER KE SR R K+ ++ K +++P
Sbjct: 1337 AKDEKFKTTVPNAESKSTQERER-EKEPSRERDIAKEMKSKENVKGGEKTPVSGSLKSPV 1395
Query: 996 RRSRSRSPKKSGKKSRSQSRSPHRSHKKSKKN 1027
RS P++ +K R P SH + K+
Sbjct: 1396 PRSDIPEPERE-QKRRKIDTHPSPSHSSTVKD 1426
Score = 39.7 bits (91), Expect = 0.015
Identities = 52/227 (22%), Positives = 93/227 (40%), Gaps = 31/227 (13%)
Query: 44 RTRPKSPRKHNYRNESARESLCDSPHQNLSRPLLENKLKAFSIGKMSTAKRTLSKKEQEE 103
+ +PK R + ++E ARE+ +P + + + + KA +T SK QE
Sbjct: 1300 KEKPKEERPN--KDEKARETKERTPKSDKEKEKFKKEEKAKDEKFKTTVPNAESKSTQER 1357
Query: 104 LKKKEDEKAAAEIYEEFLAA--FEGSDGNKVKTFVRGGVVNAAKEEHETDEKRGKIY--- 158
++KE + +I +E + +G + V ++ V + E E ++KR KI
Sbjct: 1358 EREKEPSRER-DIAKEMKSKENVKGGEKTPVSGSLKSPVPRSDIPEPEREQKRRKIDTHP 1416
Query: 159 --KPSSRFADQKNPPNQSS-----NERPPSLLVIETKKPPLKKGEKEKKKSNLELFKEEL 211
SS D +SS N PP L + ++ K +K +++S +E
Sbjct: 1417 SPSHSSTVKDSLIELKESSAKLYINHTPPPLSKSKEREMDKKDLDKSRERS-----RERE 1471
Query: 212 KQIQEERDERHKTKGRLSRFEPPQSDSDGQRRSMDAPSRRNRSSGVL 258
K+ +++R ER + R PP D RR +G +
Sbjct: 1472 KKDEKDRKERKRDHSNNDREVPP-----------DLTKRRKEENGTM 1507
Score = 32.0 bits (71), Expect = 3.1
Identities = 38/166 (22%), Positives = 60/166 (36%), Gaps = 27/166 (16%)
Query: 868 GQSFQEQVEHYRDKLLQREKEKE-----LERERERDKKDKEKLESRSKDKKEKDECTPTR 922
GQ+ + +V K+ Q EKEK L K ++ + KD P
Sbjct: 1141 GQALERRVH----KICQEEKEKRPDLYALAMGYSGQLKSRKSYMIPENEFHHKDP-PPRN 1195
Query: 923 KERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKESSRSRSSHKDSPRDVSKKA 982
++ PS SS G KS E S +E+ +SR + + V+K +
Sbjct: 1196 AVASVQNGPGGGPSSSSIGSASKS----------DESSTEETDKSRERSQCGVKAVNKAS 1245
Query: 983 KRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRSHKKSKKNK 1028
+P G+ S S S K + + + +K KK K
Sbjct: 1246 STTPKGN-------SSNGNSGSNSNKAVKENDKEKGKEKEKEKKEK 1284
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 73.2 bits (178), Expect = 1e-12
Identities = 51/187 (27%), Positives = 91/187 (48%), Gaps = 16/187 (8%)
Query: 850 KVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKE-----K 904
++ + + E+E+ K KK +S +++ R+K R++E+E ER+RER KK+K+ +
Sbjct: 37 EIREREREIETRKEGKKERESERKKERREREK---RKREREKERKRERGKKEKKGERKKE 93
Query: 905 LESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKES 964
R K ++EK+ KE KR+ R+S + + + +R ER ER K+
Sbjct: 94 ERERKKRRREKENKEGEEKE-KRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE 152
Query: 965 SRSRSSHKDSPRDVSKKAKRSPSGSRTPKR---SRRSRSRSPKKSGKKSRSQSRSPHRSH 1021
R K+ R KK +R G + +R R+ R + + ++ + + R R
Sbjct: 153 ER----EKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRER 208
Query: 1022 KKSKKNK 1028
KK +K K
Sbjct: 209 KKERKKK 215
Score = 71.6 bits (174), Expect = 4e-12
Identities = 51/213 (23%), Positives = 93/213 (43%), Gaps = 5/213 (2%)
Query: 818 SNPIKEEMTESKFSKYSEMSEEKRAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEH 877
S P + +S+ + E ++ +E E + K + E E KR + + +++
Sbjct: 26 SKPCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKRER---EKERKRERG 82
Query: 878 YRDKLLQREKEKELERERERDKKDKEKLESRSKDKKEKDECTPTRKERKRRH--STSPSP 935
++K +R+KE+ ++R R+K++KE E + KKEK E T KE K R
Sbjct: 83 KKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKRE 142
Query: 936 SRSSSGRRVKSPSPKSERSERSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRS 995
R R+ + + ER ER +R K+ K+ R KK +R+ + +
Sbjct: 143 ERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERER 202
Query: 996 RRSRSRSPKKSGKKSRSQSRSPHRSHKKSKKNK 1028
+ R R ++ K+ R + R R +K +
Sbjct: 203 KERRERKKERKKKEERKKERQKDRQTNWREKER 235
Score = 70.5 bits (171), Expect = 8e-12
Identities = 54/234 (23%), Positives = 103/234 (44%), Gaps = 25/234 (10%)
Query: 780 ELFDQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEE 839
E+ ++ E E + +E ESE +++ + + + +E + K + + E
Sbjct: 37 EIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERE 96
Query: 840 KRAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDK 899
++ + RE E K + + E K K+ G++ +E E R + +RE+ KE ER++E +
Sbjct: 97 RKKRRREKENKEGE-EKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEERE 155
Query: 900 KDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSER 959
K++E+ E + +++K+ E RKE++R+ ER +R ER
Sbjct: 156 KERERKERKKRERKQVGEKEEERKEKERK-----------------------ERKKR-ER 191
Query: 960 SHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQ 1013
+ KE + R + R +K K R R R + K +K R +
Sbjct: 192 NRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 67.8 bits (164), Expect = 5e-11
Identities = 51/230 (22%), Positives = 100/230 (43%), Gaps = 14/230 (6%)
Query: 775 TTSKWELFDQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYS 834
T W+ + E E E + ++E E E + + E K + K K
Sbjct: 30 TQPGWQSEIREREREIETRKEGKKERESERKKERRERE---------KRKREREKERKRE 80
Query: 835 EMSEEKRAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERE 894
+EK+ + ++ E + K + E E+ + +K + +E+ E R +E+E++ ER+
Sbjct: 81 RGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERK 140
Query: 895 RERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERS 954
RE ++K++E R K+++EK+ RK+R+R+ R R+ + ++ +
Sbjct: 141 RE-ERKERE----RKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKE 195
Query: 955 ERSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPK 1004
+ ER KE + K ++ K + R +R +R R K
Sbjct: 196 RKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 67.0 bits (162), Expect = 9e-11
Identities = 56/224 (25%), Positives = 102/224 (45%), Gaps = 16/224 (7%)
Query: 794 QNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLREIELKVMK 853
Q++ E E E +T+ +E + E + K + E E+ K ++ E K
Sbjct: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERK--- 91
Query: 854 FQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKLESRS--KD 911
++E E KR ++ E+ E R K ++E+ + + +ER++K++ K E R +
Sbjct: 92 -KEERERKKRRREKENKEGEEKEK-RKKKEKKERGRTSKEGKERERKEERKREERKERER 149
Query: 912 KKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKESSRSRSSH 971
KKE+ E RKERK+R R G + + K ER ER +R R +
Sbjct: 150 KKEEREKERERKERKKR-------ERKQVGEKEEERKEK-ERKERKKRERNRKERKKERE 201
Query: 972 KDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSR 1015
+ R+ K+ K+ + ++ R++ R K+ GK+ R + +
Sbjct: 202 RKERRERKKERKKKEERKKERQKDRQTNWRE-KERGKRERKERK 244
Score = 57.8 bits (138), Expect = 5e-08
Identities = 49/194 (25%), Positives = 87/194 (44%), Gaps = 21/194 (10%)
Query: 766 ESELEAQAVTTSKWELFDQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEM 825
E E E + K + ++ +E E + + +E+E+++ E+ + K +E KE
Sbjct: 72 EREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEK-------KERG 124
Query: 826 TESKFSKYSEMSEE-KRAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQ 884
SK K E EE KR + +E E K + + E E +R K+ + E+ E
Sbjct: 125 RTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEE------- 177
Query: 885 REKEKELERERERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRV 944
KEKE + ++R++ KE+ K ++E+ E +KERK++ +
Sbjct: 178 -RKEKERKERKKRERNRKER-----KKERERKERRERKKERKKKEERKKERQKDRQTNWR 231
Query: 945 KSPSPKSERSERSE 958
+ K ER ER +
Sbjct: 232 EKERGKRERKERKK 245
Score = 38.9 bits (89), Expect = 0.025
Identities = 38/156 (24%), Positives = 69/156 (44%), Gaps = 7/156 (4%)
Query: 98 KKEQEELKKKEDEKAAAEIYEEFLAAFEGSDGNKVKTFVRGGVVNAAKEEHETDEKRGKI 157
KKE+ E +K++ E+ E +G + + + KE E ++++ K
Sbjct: 60 KKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKE 119
Query: 158 YKPSSRFADQKNPPNQSSNERPPSLLVIETKKPPLKKGEKEKKKSNLELFKEELKQIQEE 217
K R ++ + ER E K+ KK E+EK++ E K E KQ+ E+
Sbjct: 120 KKERGR-TSKEGKERERKEERKRE----ERKERERKKEEREKERERKERKKRERKQVGEK 174
Query: 218 RDERHKTKGRLSRFEPPQSDSDGQRRSMDAPSRRNR 253
+ER K K R R + ++ + +++ + RR R
Sbjct: 175 EEER-KEKERKERKKRERNRKE-RKKERERKERRER 208
Score = 38.9 bits (89), Expect = 0.025
Identities = 35/164 (21%), Positives = 66/164 (40%), Gaps = 3/164 (1%)
Query: 93 KRTLSKKEQE-ELKKKEDEKAAAEIYEEFLAAFEGSDGNKVKTFVRGGVVNAAKEEHETD 151
KR KKE++ E KK+E E+ +E E K + RG KE +
Sbjct: 78 KRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKE 137
Query: 152 EKRGKIYKPSSRFADQKNPPNQSSNERPPSLLVIETKKPPLKKGEKEKKKSNLELFKEEL 211
E++ + K R +++ + + + K+ K+ E++++K KE
Sbjct: 138 ERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERK 197
Query: 212 KQIQ--EERDERHKTKGRLSRFEPPQSDSDGQRRSMDAPSRRNR 253
K+ + E R+ + + K + R + Q D R + R +
Sbjct: 198 KERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERK 241
Score = 30.8 bits (68), Expect = 6.9
Identities = 39/232 (16%), Positives = 83/232 (35%), Gaps = 26/232 (11%)
Query: 6 PGGSQKASSKTRSSDVHSSGSSDAHMDASGPS-DSDMPSRTRPKSPRKHNYRNESARESL 64
PG + + R + G + + + + R R K ++ + E E
Sbjct: 32 PGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERK 91
Query: 65 CDSPHQNLSRPLLENKLKAFSIGKMSTAKRTLSKKEQEELKKKEDEKAAAEIYEEFLAAF 124
+ + R ENK + E++E +KK+++K +E
Sbjct: 92 KEERERKKRRREKENK-----------------EGEEKEKRKKKEKKERGRTSKEGKERE 134
Query: 125 EGSDGNKVKTFVRGGVVNAAKEEHETDEKRGKIYKPSSRFADQKNPPNQSSNERPPSLLV 184
+ + + R KEE E + +R + K + +K + +
Sbjct: 135 RKEERKREERKER----ERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRE 190
Query: 185 IETKKPPLKKGEKEKKKSNLELFKEELKQIQEERDE----RHKTKGRLSRFE 232
K+ ++ KE+++ E K+E ++ + ++D R K +G+ R E
Sbjct: 191 RNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKE 242
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 73.2 bits (178), Expect = 1e-12
Identities = 67/287 (23%), Positives = 118/287 (41%), Gaps = 29/287 (10%)
Query: 760 KWEAVDESEL------EAQAVTTSKWELFDQHEESEEEENQNQEEESEDEEDTQSSK--- 810
+W D+SEL + V + ++ D SE +N++E+ + + S +
Sbjct: 379 RWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDI 438
Query: 811 ---SEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLREIELKVMKFQDELESGKRPKKP 867
SE+ Y N +K+ SK E S+ K + K E R +
Sbjct: 439 RRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKE--------RDSKHNRNEEKRMRSRSK 490
Query: 868 GQSFQEQVEHYRDKLLQRE-KEKELERERERDKKDKEKLESRSKDKKEKDECTPTRKERK 926
G+ E+ ++K Q + K K+ ER R ++K + + +S D + E + R
Sbjct: 491 GRDH----ENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRS 546
Query: 927 RRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKESSRSRSSHKDSPRDVSKKAKRSP 986
R + +S R +S S R RS ++ SRS+ H+ ++ ++ +
Sbjct: 547 RECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRS 606
Query: 987 SGSRTPK-RSR---RSRSRSPKKSGKKSRSQSRSPHRSHKKSKKNKH 1029
RTP RSR R R R +S ++ SQSR+ + + K+ H
Sbjct: 607 RERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSH 653
Score = 68.2 bits (165), Expect = 4e-11
Identities = 71/303 (23%), Positives = 135/303 (44%), Gaps = 26/303 (8%)
Query: 742 DATEDSKKNEPIFKVAPSKWEAVDESELEAQAVTTSKWELFDQHEESEEEE----NQNQE 797
++ +D K + K A SK S +++ + SK E +H +EE+ ++ ++
Sbjct: 441 NSEKDDKYKNKVKKRAKSK------SRSKSKEKSKSK-ERDSKHNRNEEKRMRSRSKGRD 493
Query: 798 EESEDEEDTQS-SKSEEHHLYSNPIKEEMTESKFSKYSEMS---EEKRAKLREIELKVMK 853
E+ E++ QS SK ++ + K + ESK +++ +++RA+ R E + K
Sbjct: 494 HENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITK 553
Query: 854 FQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKLESRSKDKK 913
+ S R + + +V R + R++ + E R R+++ + + SRS++++
Sbjct: 554 GKHSYNSRTRERSRSRDRSRRV---RSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERR 610
Query: 914 EKDECTPTRKERKRRHSTSPSPSRSSSGRRV----KSPSPKSERSERSERSHKESSRSRS 969
+ ++ R+RR + S S R S S R E SE + S+SR
Sbjct: 611 TPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSR- 669
Query: 970 SHKDSPRDVSKKAKRSPSG-SRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRSHKKSK--K 1026
H S KKA R S S+ + S+ + +S K+ S + ++KSK +
Sbjct: 670 DHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQE 729
Query: 1027 NKH 1029
N H
Sbjct: 730 NDH 732
Score = 67.8 bits (164), Expect = 5e-11
Identities = 72/291 (24%), Positives = 119/291 (40%), Gaps = 29/291 (9%)
Query: 746 DSKKNEPIFKVAPSKWEAVD-ESELEAQAVTTSKWELFDQHEESEEEENQNQEEESEDEE 804
DSK N K S+ + D E+ E + + SK + E S +E Q E +E
Sbjct: 474 DSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGK---DQERSRSKEKSKQLESKSNEH 530
Query: 805 DTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLREIELKVMKFQDELESGKRP 864
D SK ++ S + ++T+ K S S E R++ R ++ + K
Sbjct: 531 DHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEY 590
Query: 865 KKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKLESRSKDKKEKDECTPTRKE 924
+ ++EQ R + RE+ R R +D++ + + +SRS +++E +R +
Sbjct: 591 HR----YREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRR-DSRSSEREESQ----SRNK 641
Query: 925 RKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKESSRSRSSHKDSPRDVSKKAKR 984
K R+ S S R K S +R R H S+ SR D + K K+
Sbjct: 642 DKYRNQESKSSHR-------KENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQ 694
Query: 985 SPSGSRTP------KRSRRSRSRSPKKSGKKSRSQSRSPHRSHKKSKKNKH 1029
S + K + RS S +K +KS+ Q H+K+KK H
Sbjct: 695 SSQDNELKSSMLKNKEDEKIRS-SVEKENQKSKGQEND--HVHEKNKKFDH 742
Score = 49.7 bits (117), Expect = 1e-05
Identities = 72/318 (22%), Positives = 132/318 (41%), Gaps = 63/318 (19%)
Query: 770 EAQAVTTSKWELFDQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNP---IKEE-- 824
++++ T K + + +++ ++++ + + + SS+SE +L + P ++ E
Sbjct: 218 DSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEI 277
Query: 825 --MTESKF--SKYSEMSEEKRAKLREIELK---------VMKFQDEL---ESGKRPKKPG 868
+ E++F K ++EK K RE E + +Q L SG++ K G
Sbjct: 278 PPIPENRFLMRKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRG 337
Query: 869 QSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKLESRSK----DKKEKDECTPTRKE 924
R + R E +E + + ++ S + DK E +E ++
Sbjct: 338 PRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRS 397
Query: 925 RKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKESSRSRSSHKDSPRD------V 978
R + R+ S +SP+ K+E+ E+ + HK +S+ R ++S +D V
Sbjct: 398 PVRVKERKITDHRNVS----ESPNRKNEK-EKKVKDHKSNSKERDIRRNSEKDDKYKNKV 452
Query: 979 SKKAK---------RSPSGSRTPKRSR----RSRSRS-----------PKKSGKKSRSQS 1014
K+AK +S S R K +R R RSRS K+S K + Q
Sbjct: 453 KKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQE 512
Query: 1015 RSPHRSHKK---SKKNKH 1029
RS + K SK N+H
Sbjct: 513 RSRSKEKSKQLESKSNEH 530
Score = 48.9 bits (115), Expect = 2e-05
Identities = 45/162 (27%), Positives = 71/162 (43%), Gaps = 29/162 (17%)
Query: 889 KELERERERDKKD---KEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVK 945
+E+ RE E K D K E R E + +KE K+RH +S S S SSS
Sbjct: 148 QEVVREIENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSS 207
Query: 946 SPSPKSERSERSERSHKESSRSR-SSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPK 1004
S S S S SE + +E S+ R H+ + R K+ K+ K+S++S S +
Sbjct: 208 SDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKR-------KKSKKSASSESE 260
Query: 1005 KSGKKSRSQS------------------RSPHRSHKKSKKNK 1028
+++ QS +SP ++ +K +KN+
Sbjct: 261 AENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNR 302
Score = 37.7 bits (86), Expect = 0.056
Identities = 63/295 (21%), Positives = 105/295 (35%), Gaps = 51/295 (17%)
Query: 10 QKASSKTRSSDVHSSGSSDAHMDASGPSDS-DMPSRTRPKSP----------RKHNY--- 55
+K K+ SS SS SD+ D+ SDS D S T KS RKH
Sbjct: 187 EKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKK 246
Query: 56 -RNESARESLCDSPHQNLSR------------PLLENKLKAFSIGKMSTAKRTLSKKEQE 102
R +S + + +S +NL P+ EN+ + K +++ +
Sbjct: 247 KRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERER 306
Query: 103 ELKKKEDEKAAAEIYEEFLAAFEG--------------SDGNKVKTFVRGGVVNAAKEEH 148
E + A L G S F R ++E
Sbjct: 307 ERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEM 366
Query: 149 ETDEKRGKIYKPSSRFADQKNPPNQSSNERPPSLLVIETK--------KPPLKKGEKEKK 200
+ + R ++ K+ N+ + + V E K + P +K EKEKK
Sbjct: 367 QRAQ-RMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKK 425
Query: 201 -KSNLELFKEELKQIQEERDERHKTKGRLSRFEPPQSDSDGQRRSMDAPSRRNRS 254
K + KE + E+D+++K K + +S S + +S + S+ NR+
Sbjct: 426 VKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRN 480
Score = 37.4 bits (85), Expect = 0.073
Identities = 35/158 (22%), Positives = 59/158 (37%), Gaps = 27/158 (17%)
Query: 784 QHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAK 843
+ +S E + + ++D+ Q SKS S K ++S+ S S EK+A
Sbjct: 624 RRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKAD 683
Query: 844 LREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKE 903
R + P F + + +D L+ K E E+ R +KE
Sbjct: 684 -------------------RDQSP---FSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKE 721
Query: 904 KLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSG 941
+S+ ++ E K +K H +SP SG
Sbjct: 722 NQKSKGQENDHVHE-----KNKKFDHESSPGTDEDKSG 754
Score = 35.8 bits (81), Expect = 0.21
Identities = 51/248 (20%), Positives = 93/248 (37%), Gaps = 42/248 (16%)
Query: 4 KTPGGSQKASSKTRSSDV----HSSGSSDAHMDASGPSDSDMPSRT----RPKSPRKHNY 55
K+ ++A S++R D+ HS S S + SRT R +S H Y
Sbjct: 534 KSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRY 593
Query: 56 RNESARESLCDSPHQNLSRPLLENKLKAFSIGKMSTAKRTLSKKEQEELKKKEDEKAAAE 115
R + R + + P G+ + R ++ + + + E E++ +
Sbjct: 594 REQEYRRRGRSRSRERRTPP-----------GRSRSKDR---RRRRRDSRSSEREESQSR 639
Query: 116 IYEEFLAAFEGSDGNKVKTFVRGGVVNAAKEEHETDEKRGKIYKPSSRFADQKNPP---- 171
+++ S K + + + +++ + ++ R K AD+ P
Sbjct: 640 NKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKK-------ADRDQSPFSKI 692
Query: 172 NQSSNERPPSLLVIETKKPPLKKGEKEKKKSNLELFKEELKQIQEERDERHKTKGRLSRF 231
QSS + E K LK E EK +S++E KE K +E D H+ +
Sbjct: 693 KQSSQDN-------ELKSSMLKNKEDEKIRSSVE--KENQKSKGQENDHVHEKNKKFDHE 743
Query: 232 EPPQSDSD 239
P +D D
Sbjct: 744 SSPGTDED 751
Score = 35.0 bits (79), Expect = 0.36
Identities = 30/149 (20%), Positives = 57/149 (38%), Gaps = 12/149 (8%)
Query: 881 KLLQREKEKELERERERDKKDKEKLES---------RSKDKKEKDECTPTR-KERKRRHS 930
+L+ + K K+ E++R + S S D + + T + K+RK++H
Sbjct: 176 ELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHR 235
Query: 931 TSPSPSRSSSGRRVKSPSPKSERSERSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSR 990
+ + +R KS S SE + S R ++ P + S +
Sbjct: 236 KNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRP--EEIPPIPENRFLMRKSPPK 293
Query: 991 TPKRSRRSRSRSPKKSGKKSRSQSRSPHR 1019
++ R++R R ++ SQ S R
Sbjct: 294 ADEKERKNRERERERECNPPNSQPASYQR 322
>gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens]
Length = 951
Score = 73.2 bits (178), Expect = 1e-12
Identities = 90/351 (25%), Positives = 140/351 (39%), Gaps = 60/351 (17%)
Query: 725 DGVPIKSLDDDLDGVPLDATE-------------DSKKNEPIFKVAPSKWE----AVDES 767
D P K D DG P DA E S K P K+ + + A+
Sbjct: 527 DSAPEKPSDAGEDGAPEDAAEVGARAGSGGKKEASSSKTVPDGKLVKASFAPISFAIKAK 586
Query: 768 ELEAQAVTTSKWELFDQHEESEEEENQNQEEES-------------------------ED 802
E + + ++ +L D + +EE + QE S E+
Sbjct: 587 ENDLLPLEKNRVKL-DDDSDDDEESKEGQESSSSAANTNPAVAPPCVVVEEKKPQLTQEE 645
Query: 803 EEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLREIELKVMKFQDELESGK 862
E Q+ + E L + ++ SK SK ++ E++ K + E E+GK
Sbjct: 646 LEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTLKNPLPEAEAGK 705
Query: 863 RPKKPGQSFQEQVEHYRDKLLQREKEKELE---RERERDK-KDKEKLESRSKDKKEKDEC 918
+ P S +E L LE +R K KD + E + K KK+ +
Sbjct: 706 IEESPF-SVEESSTTPCPLLTGGRPLPTLEVKPPDRPSSKSKDPPREEEKEKKKKKHKKR 764
Query: 919 TPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKESSRSRSSHKDSPRD- 977
+ TR + HS+S S SRS S + K P + R+ R RS S R R+ + R+
Sbjct: 765 SRTRSRSPKYHSSSKSRSRSHS--KAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREE 822
Query: 978 ----VSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRSHKKS 1024
+ + RSP SR +R+RSRSP + KK RS+SR+ ++ +S
Sbjct: 823 RSVPTAYRVSRSPGASR-----KRTRSRSPHEKKKKRRSRSRTKSKARSQS 868
Score = 64.7 bits (156), Expect = 4e-10
Identities = 76/321 (23%), Positives = 136/321 (42%), Gaps = 43/321 (13%)
Query: 732 LDDDLDGVPLDATEDSKKNE--------------PIFKVAPSKWEAVDESELEAQAVTTS 777
LDDD D E+SK+ + P V K + + ELEA+ +
Sbjct: 600 LDDDSDD-----DEESKEGQESSSSAANTNPAVAPPCVVVEEKKPQLTQEELEAKQ---A 651
Query: 778 KWELFDQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMS 837
K +L D+ + E+ +ES+ E+ Q+ + + L+ +K + E++ K
Sbjct: 652 KQKLEDRLAAAAREKLAQASKESK-EKQLQAERKRKAALFLQTLKNPLPEAEAGKI---- 706
Query: 838 EEKRAKLREIELKVMKFQDELESGKRP------KKPGQSFQEQVEHYRDKLLQREKEKEL 891
EE + E L +G RP K P + + + R++ +++K+K
Sbjct: 707 EESPFSVEESSTTPCP----LLTGGRPLPTLEVKPPDRPSSKSKDPPREEEKEKKKKKHK 762
Query: 892 ERERERDKKDKEKLESRSKDK---KEKDECTPTRKERKRRHSTSPSPSR---SSSGRRVK 945
+R R R + K S+S+ + K K + +R S S SP R S RR +
Sbjct: 763 KRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREE 822
Query: 946 SPSPKSERSERSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKK 1005
P + R RS + ++ +RSRS H+ + S+ +S + S++ S+++ R
Sbjct: 823 RSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAP 882
Query: 1006 SGKKSRSQSRSPHRSHKKSKK 1026
+ + S S SP S S++
Sbjct: 883 AAHSAHSASVSPVESRGSSQE 903
Score = 53.5 bits (127), Expect = 1e-06
Identities = 66/283 (23%), Positives = 118/283 (41%), Gaps = 38/283 (13%)
Query: 772 QAVTTSKWELFDQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEE--MTESK 829
QAV+ + D E + ++ E E ++ + S+ + + ++
Sbjct: 516 QAVSAPEEAPTDSAPEKPSDAGEDGAPEDAAEVGARAGSGGKKEASSSKTVPDGKLVKAS 575
Query: 830 FSKYSEMSEEKRAKLREIELKVMKFQDELESGKRPKKPGQSFQEQ-------------VE 876
F+ S + K L +E +K D+ + + K+ +S VE
Sbjct: 576 FAPISFAIKAKENDLLPLEKNRVKLDDDSDDDEESKEGQESSSSAANTNPAVAPPCVVVE 635
Query: 877 HYRDKLLQREKEKELERERERDK---KDKEKLESRSKDKKEKDECTPTRKERKRRHSTSP 933
+ +L Q E E + +++ D+ +EKL SK+ KEK + ERKR+ +
Sbjct: 636 EKKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQ----LQAERKRKAALFL 691
Query: 934 SPSRSSSGRRVKSPSPKSE--RSERSERSHKESSRSR----SSHKDSPRDVSKKAKRSPS 987
+ +K+P P++E + E S S +ESS + + + P K R S
Sbjct: 692 --------QTLKNPLPEAEAGKIEESPFSVEESSTTPCPLLTGGRPLPTLEVKPPDRPSS 743
Query: 988 GSRTPKRSRRSRSRSPKKSGKKSRSQSRSP-HRSHKKSKKNKH 1029
S+ P R + + KK K+SR++SRSP + S KS+ H
Sbjct: 744 KSKDPPREEE-KEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSH 785
Score = 37.7 bits (86), Expect = 0.056
Identities = 36/123 (29%), Positives = 49/123 (39%), Gaps = 29/123 (23%)
Query: 373 TLPPPPSGLPFNAQPRERLKNPNAPMLPPPKNKEDFE-------KTLSQAIVKVVIPTER 425
T PPPP P LPPP E T + A V +IP
Sbjct: 411 TAPPPPGTTP----------------LPPPTTAETSSGATSTTTTTSALAPVAAIIPPPP 454
Query: 426 NLLALIHRMIEFVVREGPMFEAMIMNREINNPMFRFLFENQTPAHVYYRWKLYSILQ--- 482
++ +I ++ E+V R G FE + R N+ F FL + + YY +K LQ
Sbjct: 455 DVQPVIDKLAEYVARNGLKFETSV--RAKNDQRFEFL-QPWHQYNAYYEFKKQFFLQKEG 511
Query: 483 GDS 485
GDS
Sbjct: 512 GDS 514
Score = 36.6 bits (83), Expect = 0.13
Identities = 20/61 (32%), Positives = 31/61 (50%), Gaps = 1/61 (1%)
Query: 403 KNKEDFEKTLSQAIVK-VVIPTERNLLALIHRMIEFVVREGPMFEAMIMNREINNPMFRF 461
+N+E F L ++ V +P + A+I R FV R+G FE M+ ++ N F F
Sbjct: 183 ENEEPFVAPLGLSVPSDVELPPTAKMHAIIERTASFVCRQGAQFEIMLKAKQARNSQFDF 242
Query: 462 L 462
L
Sbjct: 243 L 243
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sapiens]
Length = 805
Score = 72.0 bits (175), Expect = 3e-12
Identities = 59/227 (25%), Positives = 107/227 (47%), Gaps = 6/227 (2%)
Query: 791 EENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLREIELK 850
E N+ + + + ++S E +P +E S+ + R++ R+ K
Sbjct: 583 ESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRD-RRK 641
Query: 851 VMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQRE-KEKELERERERDKKDKEKLESRS 909
+ + L SG K G++ +++ + R + + ++ K+K+ ERERE+DK+ KEK +
Sbjct: 642 IDDQRGNL-SGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKR-KEKQKREE 699
Query: 910 KDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKESSRSRS 969
KD K + +++R+ + S S S S R S + + + + H S S
Sbjct: 700 KDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGR 759
Query: 970 SHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRS 1016
S +SP +K + P SR+ RS RS KK+ +K +S+SRS
Sbjct: 760 SSSESPGSSKEKKAKKPKHSRS--RSVEKSQRSGKKASRKHKSKSRS 804
Score = 62.8 bits (151), Expect = 2e-09
Identities = 70/290 (24%), Positives = 112/290 (38%), Gaps = 35/290 (12%)
Query: 775 TTSKWELFDQHEESEEEENQNQEEESEDEEDTQS-----SKSEEHHLYSNPIKEEMTESK 829
TTS E +H+E E++ S + S S + YS+ T S+
Sbjct: 489 TTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSR 548
Query: 830 FSKYSEMSEEKRAKLREIELKVMKFQD-----ELESGKRPKK---PGQSFQEQVEHYRDK 881
S R++ I+ + + + ++ES + K +S + +E R +
Sbjct: 549 SSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRR 608
Query: 882 LLQREKEKELERERERDKKDKEKLESRSKDKKEKDECTPT-------------RKERKRR 928
+E+ R R RD++ SRS+D+++ D+ +ERK+
Sbjct: 609 NRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKE 668
Query: 929 HSTSPSPSRSSSGR-RVKSPSPKSERSERSERSHKESS------RSRSSHKDSPRDVSKK 981
S S R + R + + E+ +R E+ K SS R R S + R S
Sbjct: 669 RSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSIS 728
Query: 982 AKRSPSGSRTP-KRSRRSRSRSPKKSGKKSRSQSRSPHRS-HKKSKKNKH 1029
K SR K+S S+ S RS S SP S KK+KK KH
Sbjct: 729 VKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKH 778
Score = 60.5 bits (145), Expect = 8e-09
Identities = 66/265 (24%), Positives = 114/265 (43%), Gaps = 27/265 (10%)
Query: 787 ESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLR- 845
E E + ++ +++DEE + ++ + ++++ K +M EEK+ R
Sbjct: 397 EDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDK-----QMEEEKQQTERV 451
Query: 846 --EIELKVMKFQDELESGKRPKKPGQSFQEQ--VEHYRDKLLQREKE-KELERERERDKK 900
E+ + K Q+ L + + G E+ + +L+ +KE KE E++
Sbjct: 452 TKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSG 511
Query: 901 DKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVK------SPSPKSERS 954
S S + T + +S + SRSSS +R K SP+ K+ RS
Sbjct: 512 SSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRS 571
Query: 955 ER---SERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRS-RRSRSRS-PKKSGKK 1009
S R ES+R+R +D R +R +R+P R RRSRSRS +++ +
Sbjct: 572 RSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRA 631
Query: 1010 SRSQSR-----SPHRSHKKSKKNKH 1029
SRS+SR R + +KH
Sbjct: 632 SRSRSRDRRKIDDQRGNLSGNSHKH 656
Score = 58.2 bits (139), Expect = 4e-08
Identities = 73/313 (23%), Positives = 121/313 (38%), Gaps = 67/313 (21%)
Query: 782 FDQHEESEEEENQN--------------QEEESEDEEDTQSSKSEEHHLYSNPIKEE--- 824
FD EE E+ EN +EE D E T+ K + L + + E
Sbjct: 288 FDSDEEEEDTENVEAASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILL 347
Query: 825 -MTESKFSKYSEMSEEKRAKLREIELKVMKF----------------QDELESGKRPKKP 867
+T+ + ++ + K K +L E E R +
Sbjct: 348 DVTDEEIYYVAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSES 407
Query: 868 GQSFQEQVEH----YRDKLLQREKEKEL--ERERERDKKDKEK----------------- 904
+ E++ H ++ ++EKE++L +++ E +K+ E+
Sbjct: 408 SDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLS 467
Query: 905 -LESRSKD------KKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERS 957
LE+R D KK T + E K+ H RS SG S + R+ +
Sbjct: 468 LLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSST 527
Query: 958 ERSHKESSRSRS--SHKDSPRDVSKKAKRSPSGSRTPK-RSRRSRSRSPKKSGKKSRSQS 1014
+ SS S S S + S R S K K+ S SR+P ++RRSRSRS + K +++
Sbjct: 528 SSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRA 587
Query: 1015 RSPHRSHKKSKKN 1027
R R ++S +N
Sbjct: 588 RVKIRDRRRSNRN 600
Score = 47.4 bits (111), Expect = 7e-05
Identities = 41/187 (21%), Positives = 78/187 (41%), Gaps = 26/187 (13%)
Query: 783 DQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRA 842
DQ ++++ E E E + S+S + K K E ++KR
Sbjct: 644 DQRGNLSGNSHKHKGEAKEQERKKERSRSIDKD-----------RKKKDKEREREQDKRK 692
Query: 843 KLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDK 902
+ ++ E K KF + + KR ++ ++F K+++ + ++ ++ +D K
Sbjct: 693 EKQKREEKDFKFSSQDDRLKRKRESERTFSRSGS-ISVKIIRHDSRQDSKKSTTKDSKKH 751
Query: 903 EKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERS-ERSERSH 961
+S + E + +K +K +HS S S KS+RS +++ R H
Sbjct: 752 SGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVE-------------KSQRSGKKASRKH 798
Query: 962 KESSRSR 968
K SRSR
Sbjct: 799 KSKSRSR 805
Score = 38.5 bits (88), Expect = 0.033
Identities = 44/202 (21%), Positives = 85/202 (42%), Gaps = 20/202 (9%)
Query: 36 PSDSDMPSRTRPKSPRKHNY-RNESARESLCDSPHQNLSRPLLENKLKAFSIGKMSTAKR 94
PS SR+R + R + R+ S D NLS ++K +A + R
Sbjct: 612 PSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSR 671
Query: 95 TLSK---KEQEELKKKEDEKAAAEIYEEFLAAFEGSDGN------KVKTFVRGGVVNAAK 145
++ K K+ +E ++++D++ + EE F D +TF R G ++
Sbjct: 672 SIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKI 731
Query: 146 EEHETDEKRGKIYKPSSRFADQKNPPNQSSNERPPSLLVIETKKPPLKKGEKEKKKSNLE 205
H++ + K S+ + +SS+E P S +K+ KK + + +S
Sbjct: 732 IRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGS-----SKEKKAKKPKHSRSRS--- 783
Query: 206 LFKEELKQIQEERDERHKTKGR 227
E+ ++ ++ +HK+K R
Sbjct: 784 --VEKSQRSGKKASRKHKSKSR 803
Score = 33.5 bits (75), Expect = 1.1
Identities = 56/262 (21%), Positives = 102/262 (38%), Gaps = 24/262 (9%)
Query: 9 SQKASSKTRSSDVHSSGSSDAHMDASGPSDSDMPSRTRPKSPRKHNYRNESARESLCDSP 68
S +S+ + SS SSGSS +S P SR+R SP R+ S S
Sbjct: 525 SSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSR--SPTIKARRSRSRSYSRRIKI 582
Query: 69 HQNLSRPLLENKLKA--FSIGKMSTAKRTLSKKEQEELKKKEDEKAAAEIYEEFLAAFEG 126
N +R + ++ ++ SI + R+ S++ + + D + A
Sbjct: 583 ESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTN--------RASRS 634
Query: 127 SDGNKVKTFVRGGVVNAAKEEHETDEKRGKIYKPSSRFADQKNPPNQSSNERPPSLLVIE 186
++ K + G ++ +H+ + K + K SR D+ ER +
Sbjct: 635 RSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQ-----D 689
Query: 187 TKKPPLKKGEKEKKKSNLELFKEELKQIQEERDERHKTKGRLSRFEPPQSDSDGQRRSMD 246
+K K+ EK+ K S+ + + LK+ + E + G +S ++S
Sbjct: 690 KRKEKQKREEKDFKFSSQD---DRLKR-KRESERTFSRSGSISVKIIRHDSRQDSKKSTT 745
Query: 247 APSRRNR---SSGVLDDYAPGS 265
S+++ SSG +PGS
Sbjct: 746 KDSKKHSGSDSSGRSSSESPGS 767
Score = 32.3 bits (72), Expect = 2.4
Identities = 27/141 (19%), Positives = 56/141 (39%), Gaps = 12/141 (8%)
Query: 864 PKKPGQSFQEQVEHYRDK------LLQREKEKELERERERD-----KKDKEKLESRSKDK 912
P P Q+ +E+ +RD+ L +++ +++ + R ++ EK+E + K
Sbjct: 191 PPAPPQNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQKK 250
Query: 913 KEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKESSRSRSSHK 972
EK+ R + ++ + + G R+ S K + E E + + S
Sbjct: 251 LEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRS-KFDSDEEEEDTENVEAASSGKVT 309
Query: 973 DSPRDVSKKAKRSPSGSRTPK 993
SP V ++ P + K
Sbjct: 310 RSPSPVPQEEHSDPEMTEEEK 330
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 72.0 bits (175), Expect = 3e-12
Identities = 75/283 (26%), Positives = 113/283 (39%), Gaps = 58/283 (20%)
Query: 761 WEAVDESELEAQAVTTSKWELFDQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNP 820
W Q T + + + E E EN+ +E E E E D + + +
Sbjct: 380 WRGGQYENFRVQYTETEPYHNYRERERERERENRQRERERERERDRERERRQRER----- 434
Query: 821 IKEEMTESKFSKYSEMSEEKRAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRD 880
E +R R+ E + K + E E KR +K Q +RD
Sbjct: 435 -----------------EREREHERDKERQRRKEEWERERAKRDEKDRQ--------HRD 469
Query: 881 KLLQREKEKELERERERDKKDKEKLESRSKDKKEKDECT-------------PTRKER-- 925
R++EKE E+E+ + K + SR + +K+ T P R+ +
Sbjct: 470 ----RDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSP 525
Query: 926 KRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKESSRSRS-SHKDSPRDVSKKAKR 984
K++ S SPSR+ R+ + S + S RS SSRS S S S R S+ +
Sbjct: 526 KKKLGVSVSPSRARRRRKTSASSASASNSSRS------SSRSSSYSGSGSSRSRSRSSSY 579
Query: 985 SPSGSRTPKRS--RRSRSRSPKKSGKKSRSQSRSPHRSHKKSK 1025
S SR+ + S SRSRS S S S + SPHR ++K
Sbjct: 580 SSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTK 622
Score = 64.3 bits (155), Expect = 6e-10
Identities = 56/200 (28%), Positives = 90/200 (45%), Gaps = 15/200 (7%)
Query: 840 KRAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDK 899
+R + RE E + + + E E + ++ + + + EH RDK QR KE E ERER K
Sbjct: 403 ERERERERENRQRERERERERDRERERRQREREREREHERDKERQRRKE---EWERERAK 459
Query: 900 KDKEKLESRSKDK-----KEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERS 954
+D++ + R +D+ KEK + P + R + P +++G +VK +
Sbjct: 460 RDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPW 519
Query: 955 ERSERSHKE------SSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGK 1008
RS+ K+ SR+R K S S + S S SR+ S SRS +S
Sbjct: 520 RRSKSPKKKLGVSVSPSRARRRRKTSASSASA-SNSSRSSSRSSSYSGSGSSRSRSRSSS 578
Query: 1009 KSRSQSRSPHRSHKKSKKNK 1028
S SRS S +++
Sbjct: 579 YSSYSSRSSRHSSFSGSRSR 598
Score = 61.6 bits (148), Expect = 4e-09
Identities = 55/209 (26%), Positives = 96/209 (45%), Gaps = 21/209 (10%)
Query: 832 KYSEMSEEKRAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKEL 891
+Y+E + RE E + Q E E + + + Q + E R+ E++KE
Sbjct: 391 QYTETEPYHNYRERERERERENRQRERERERERDRERERRQRERERERE----HERDKER 446
Query: 892 ER-----ERERDKKDKEKLESRSKDK-----KEKDECTPTRKERKRRHSTSPSPSRSSSG 941
+R ERER K+D++ + R +D+ KEK + P + R + P +++G
Sbjct: 447 QRRKEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTG 506
Query: 942 RRVKSPSPKSERSERSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSR 1001
+VK + RS+ K+ S S + +++ +++ + S + S RS SR
Sbjct: 507 PQVKRADEWKDPWRRSKSPKKKLGVSVSPSR------ARRRRKTSASSASASNSSRSSSR 560
Query: 1002 SPKKSGK-KSRSQSRSPHRSHKKSKKNKH 1029
S SG SRS+SRS S S+ ++H
Sbjct: 561 SSSYSGSGSSRSRSRSSSYSSYSSRSSRH 589
Score = 51.2 bits (121), Expect = 5e-06
Identities = 37/137 (27%), Positives = 65/137 (47%), Gaps = 13/137 (9%)
Query: 789 EEEENQNQEEESEDEEDTQSSKSEEHHLY----SNPIKEEMTESKFSKYSEMSEEKRAKL 844
EEE+N + EE+ E +Q SE + L S+P +EE E + + S++ +E +
Sbjct: 61 EEEDNHSDEEDRASEPKSQDQDSEVNELSRGPTSSPCEEEGDEGEEDRTSDLRDEASSVT 120
Query: 845 REIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERER----DKK 900
RE++ + + +E+ P++P + QE EK + RE +
Sbjct: 121 RELDEHELDYDEEV-----PEEPAPAVQEDEAEKAGAEDDEEKGEGTPREEGKAGVQSVG 175
Query: 901 DKEKLESRSKDKKEKDE 917
+KE LE+ + KKE D+
Sbjct: 176 EKESLEAAKEKKKEDDD 192
Score = 48.9 bits (115), Expect = 2e-05
Identities = 65/300 (21%), Positives = 105/300 (35%), Gaps = 25/300 (8%)
Query: 726 GVPIKSLDDDLDGVPLDATEDSKKNEPIFKVAPSKWEAVDESELEAQAVTTSKWELFDQH 785
G +K D+ D P ++ KK + V+PS+ A + A + + S
Sbjct: 506 GPQVKRADEWKD--PWRRSKSPKKKLGV-SVSPSR--ARRRRKTSASSASASNSSRSSSR 560
Query: 786 EESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLR 845
S ++ + SS+S H +S + S S R +R
Sbjct: 561 SSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIR 620
Query: 846 EIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKL 905
G+ PG++ ++ V+ + K E K
Sbjct: 621 T-------------KGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPG---- 663
Query: 906 ESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKESS 965
+ R +KE+ TP R+ + S S S R +S S S S S S S+
Sbjct: 664 DPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSA 723
Query: 966 RSRSS---HKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRSHK 1022
S S + D VS + RSP+ ++T K +S+ K K+ R S P +S K
Sbjct: 724 HSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAK 783
Score = 37.4 bits (85), Expect = 0.073
Identities = 51/228 (22%), Positives = 85/228 (37%), Gaps = 17/228 (7%)
Query: 799 ESEDE-EDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLREIELKVMKFQDE 857
+SED D S S P + + K K + EEKR R+ + K
Sbjct: 727 DSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRK--RDSSTQPPKSAKP 784
Query: 858 LESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELER-ERERDKKDKEKLESRSKDKK--- 913
GK ++P Q + KE +L + DK +++ E KD++
Sbjct: 785 PAGGKSSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPP 844
Query: 914 --EKDECTPTRKERKRRHST---SPSPSRSSSGRRVKSPSPKSERSERSERSHKESSRSR 968
++ +P R R R+ SP P R G+ K+P+ ++R + K SS+
Sbjct: 845 PAKRPNTSPDRGSRDRKSGGRLGSPKPERQR-GQNSKAPAAPADRKRQLSPQSKSSSKVT 903
Query: 969 SSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRS 1016
S P S S + SRR K+ + + ++ R+
Sbjct: 904 S----VPGKASDPGAASTKSGKASTLSRREELLKQLKAVEDAIARKRA 947
Score = 36.2 bits (82), Expect = 0.16
Identities = 38/147 (25%), Positives = 60/147 (40%), Gaps = 24/147 (16%)
Query: 906 ESRSKDKKEKDECTPTRKERKRRHSTSPSPSRS--SSGRRVKSPS-----PKSERSERSE 958
++R + K K E ++RKR ST P S + G+ + PS P + + +
Sbjct: 751 QTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQGTF 810
Query: 959 RSHKE------------SSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSR--SPK 1004
+HKE SR R D R AKR + R R+S R SPK
Sbjct: 811 VAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRGSRDRKSGGRLGSPK 870
Query: 1005 ---KSGKKSRSQSRSPHRSHKKSKKNK 1028
+ G+ S++ + R + S ++K
Sbjct: 871 PERQRGQNSKAPAAPADRKRQLSPQSK 897
Score = 35.4 bits (80), Expect = 0.28
Identities = 40/193 (20%), Positives = 84/193 (43%), Gaps = 20/193 (10%)
Query: 700 EEELDGAPLEDVDGIPIDATPIDDLDGVPIKSLD-DDLDGVPLDATEDSKKNEPIFKVAP 758
E+E L D D I D+ DLDG +++ D +D + +++ + N +
Sbjct: 15 EDEEQPQGLSD-DDILRDSGSDQDLDGAGVRASDLEDEESAARGPSQEEEDNHSDEEDRA 73
Query: 759 SKWEAVDESELEAQAVTTSKWELFDQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYS 818
S+ ++ D+ +++ S+ EE +E +++ + DE + + + +EH L
Sbjct: 74 SEPKSQDQ---DSEVNELSRGPTSSPCEEEGDEGEEDRTSDLRDEASSVTRELDEHELDY 130
Query: 819 NPIKEEMTESKFSKYSEMSEEKRAKLREIELKVMKFQDELESGK-RPKKPGQSFQEQVEH 877
+ E+ EE ++E E + +D+ E G+ P++ G++ + V
Sbjct: 131 D--------------EEVPEEPAPAVQEDEAEKAGAEDDEEKGEGTPREEGKAGVQSVGE 176
Query: 878 YRDKLLQREKEKE 890
+EK+KE
Sbjct: 177 KESLEAAKEKKKE 189
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sapiens]
Length = 805
Score = 72.0 bits (175), Expect = 3e-12
Identities = 59/227 (25%), Positives = 107/227 (47%), Gaps = 6/227 (2%)
Query: 791 EENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLREIELK 850
E N+ + + + ++S E +P +E S+ + R++ R+ K
Sbjct: 583 ESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRD-RRK 641
Query: 851 VMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQRE-KEKELERERERDKKDKEKLESRS 909
+ + L SG K G++ +++ + R + + ++ K+K+ ERERE+DK+ KEK +
Sbjct: 642 IDDQRGNL-SGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKR-KEKQKREE 699
Query: 910 KDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKESSRSRS 969
KD K + +++R+ + S S S S R S + + + + H S S
Sbjct: 700 KDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGR 759
Query: 970 SHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRS 1016
S +SP +K + P SR+ RS RS KK+ +K +S+SRS
Sbjct: 760 SSSESPGSSKEKKAKKPKHSRS--RSVEKSQRSGKKASRKHKSKSRS 804
Score = 62.8 bits (151), Expect = 2e-09
Identities = 70/290 (24%), Positives = 112/290 (38%), Gaps = 35/290 (12%)
Query: 775 TTSKWELFDQHEESEEEENQNQEEESEDEEDTQS-----SKSEEHHLYSNPIKEEMTESK 829
TTS E +H+E E++ S + S S + YS+ T S+
Sbjct: 489 TTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSR 548
Query: 830 FSKYSEMSEEKRAKLREIELKVMKFQD-----ELESGKRPKK---PGQSFQEQVEHYRDK 881
S R++ I+ + + + ++ES + K +S + +E R +
Sbjct: 549 SSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRR 608
Query: 882 LLQREKEKELERERERDKKDKEKLESRSKDKKEKDECTPT-------------RKERKRR 928
+E+ R R RD++ SRS+D+++ D+ +ERK+
Sbjct: 609 NRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKE 668
Query: 929 HSTSPSPSRSSSGR-RVKSPSPKSERSERSERSHKESS------RSRSSHKDSPRDVSKK 981
S S R + R + + E+ +R E+ K SS R R S + R S
Sbjct: 669 RSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSIS 728
Query: 982 AKRSPSGSRTP-KRSRRSRSRSPKKSGKKSRSQSRSPHRS-HKKSKKNKH 1029
K SR K+S S+ S RS S SP S KK+KK KH
Sbjct: 729 VKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKH 778
Score = 60.5 bits (145), Expect = 8e-09
Identities = 66/265 (24%), Positives = 114/265 (43%), Gaps = 27/265 (10%)
Query: 787 ESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLR- 845
E E + ++ +++DEE + ++ + ++++ K +M EEK+ R
Sbjct: 397 EDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDK-----QMEEEKQQTERV 451
Query: 846 --EIELKVMKFQDELESGKRPKKPGQSFQEQ--VEHYRDKLLQREKE-KELERERERDKK 900
E+ + K Q+ L + + G E+ + +L+ +KE KE E++
Sbjct: 452 TKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSG 511
Query: 901 DKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVK------SPSPKSERS 954
S S + T + +S + SRSSS +R K SP+ K+ RS
Sbjct: 512 SSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRS 571
Query: 955 ER---SERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRS-RRSRSRS-PKKSGKK 1009
S R ES+R+R +D R +R +R+P R RRSRSRS +++ +
Sbjct: 572 RSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRA 631
Query: 1010 SRSQSR-----SPHRSHKKSKKNKH 1029
SRS+SR R + +KH
Sbjct: 632 SRSRSRDRRKIDDQRGNLSGNSHKH 656
Score = 58.2 bits (139), Expect = 4e-08
Identities = 73/313 (23%), Positives = 121/313 (38%), Gaps = 67/313 (21%)
Query: 782 FDQHEESEEEENQN--------------QEEESEDEEDTQSSKSEEHHLYSNPIKEE--- 824
FD EE E+ EN +EE D E T+ K + L + + E
Sbjct: 288 FDSDEEEEDTENVEAASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILL 347
Query: 825 -MTESKFSKYSEMSEEKRAKLREIELKVMKF----------------QDELESGKRPKKP 867
+T+ + ++ + K K +L E E R +
Sbjct: 348 DVTDEEIYYVAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSES 407
Query: 868 GQSFQEQVEH----YRDKLLQREKEKEL--ERERERDKKDKEK----------------- 904
+ E++ H ++ ++EKE++L +++ E +K+ E+
Sbjct: 408 SDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLS 467
Query: 905 -LESRSKD------KKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERS 957
LE+R D KK T + E K+ H RS SG S + R+ +
Sbjct: 468 LLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSST 527
Query: 958 ERSHKESSRSRS--SHKDSPRDVSKKAKRSPSGSRTPK-RSRRSRSRSPKKSGKKSRSQS 1014
+ SS S S S + S R S K K+ S SR+P ++RRSRSRS + K +++
Sbjct: 528 SSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRA 587
Query: 1015 RSPHRSHKKSKKN 1027
R R ++S +N
Sbjct: 588 RVKIRDRRRSNRN 600
Score = 47.4 bits (111), Expect = 7e-05
Identities = 41/187 (21%), Positives = 78/187 (41%), Gaps = 26/187 (13%)
Query: 783 DQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRA 842
DQ ++++ E E E + S+S + K K E ++KR
Sbjct: 644 DQRGNLSGNSHKHKGEAKEQERKKERSRSIDKD-----------RKKKDKEREREQDKRK 692
Query: 843 KLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDK 902
+ ++ E K KF + + KR ++ ++F K+++ + ++ ++ +D K
Sbjct: 693 EKQKREEKDFKFSSQDDRLKRKRESERTFSRSGS-ISVKIIRHDSRQDSKKSTTKDSKKH 751
Query: 903 EKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERS-ERSERSH 961
+S + E + +K +K +HS S S KS+RS +++ R H
Sbjct: 752 SGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVE-------------KSQRSGKKASRKH 798
Query: 962 KESSRSR 968
K SRSR
Sbjct: 799 KSKSRSR 805
Score = 38.5 bits (88), Expect = 0.033
Identities = 44/202 (21%), Positives = 85/202 (42%), Gaps = 20/202 (9%)
Query: 36 PSDSDMPSRTRPKSPRKHNY-RNESARESLCDSPHQNLSRPLLENKLKAFSIGKMSTAKR 94
PS SR+R + R + R+ S D NLS ++K +A + R
Sbjct: 612 PSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSR 671
Query: 95 TLSK---KEQEELKKKEDEKAAAEIYEEFLAAFEGSDGN------KVKTFVRGGVVNAAK 145
++ K K+ +E ++++D++ + EE F D +TF R G ++
Sbjct: 672 SIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKI 731
Query: 146 EEHETDEKRGKIYKPSSRFADQKNPPNQSSNERPPSLLVIETKKPPLKKGEKEKKKSNLE 205
H++ + K S+ + +SS+E P S +K+ KK + + +S
Sbjct: 732 IRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGS-----SKEKKAKKPKHSRSRS--- 783
Query: 206 LFKEELKQIQEERDERHKTKGR 227
E+ ++ ++ +HK+K R
Sbjct: 784 --VEKSQRSGKKASRKHKSKSR 803
Score = 33.5 bits (75), Expect = 1.1
Identities = 56/262 (21%), Positives = 102/262 (38%), Gaps = 24/262 (9%)
Query: 9 SQKASSKTRSSDVHSSGSSDAHMDASGPSDSDMPSRTRPKSPRKHNYRNESARESLCDSP 68
S +S+ + SS SSGSS +S P SR+R SP R+ S S
Sbjct: 525 SSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSR--SPTIKARRSRSRSYSRRIKI 582
Query: 69 HQNLSRPLLENKLKA--FSIGKMSTAKRTLSKKEQEELKKKEDEKAAAEIYEEFLAAFEG 126
N +R + ++ ++ SI + R+ S++ + + D + A
Sbjct: 583 ESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTN--------RASRS 634
Query: 127 SDGNKVKTFVRGGVVNAAKEEHETDEKRGKIYKPSSRFADQKNPPNQSSNERPPSLLVIE 186
++ K + G ++ +H+ + K + K SR D+ ER +
Sbjct: 635 RSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQ-----D 689
Query: 187 TKKPPLKKGEKEKKKSNLELFKEELKQIQEERDERHKTKGRLSRFEPPQSDSDGQRRSMD 246
+K K+ EK+ K S+ + + LK+ + E + G +S ++S
Sbjct: 690 KRKEKQKREEKDFKFSSQD---DRLKR-KRESERTFSRSGSISVKIIRHDSRQDSKKSTT 745
Query: 247 APSRRNR---SSGVLDDYAPGS 265
S+++ SSG +PGS
Sbjct: 746 KDSKKHSGSDSSGRSSSESPGS 767
Score = 32.3 bits (72), Expect = 2.4
Identities = 27/141 (19%), Positives = 56/141 (39%), Gaps = 12/141 (8%)
Query: 864 PKKPGQSFQEQVEHYRDK------LLQREKEKELERERERD-----KKDKEKLESRSKDK 912
P P Q+ +E+ +RD+ L +++ +++ + R ++ EK+E + K
Sbjct: 191 PPAPPQNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQKK 250
Query: 913 KEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKESSRSRSSHK 972
EK+ R + ++ + + G R+ S K + E E + + S
Sbjct: 251 LEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRS-KFDSDEEEEDTENVEAASSGKVT 309
Query: 973 DSPRDVSKKAKRSPSGSRTPK 993
SP V ++ P + K
Sbjct: 310 RSPSPVPQEEHSDPEMTEEEK 330
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 71.6 bits (174), Expect = 4e-12
Identities = 52/243 (21%), Positives = 103/243 (42%), Gaps = 19/243 (7%)
Query: 779 WELFDQHEESEEEENQNQE----EESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYS 834
W L H++++ ++ Q + E++E E D + E K ++
Sbjct: 63 WGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIE 122
Query: 835 EMSEEKRAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERE 894
E ++ K RE E +D +R + + + Q E RD ++E E ERE
Sbjct: 123 RDREREKQKGRERE------RDRGRERERDRDREKERERQTEKDRDG----QRETETERE 172
Query: 895 RERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERS 954
R+R+++ +++ E+ ++++D T KER+R+ R + R + + ER
Sbjct: 173 RDREREKQKERET----ERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGER- 227
Query: 955 ERSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQS 1014
E R ++ R R +D RD ++ K+ R +R + + ++ K+ +
Sbjct: 228 ETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGEG 287
Query: 1015 RSP 1017
SP
Sbjct: 288 ISP 290
Score = 70.9 bits (172), Expect = 6e-12
Identities = 61/248 (24%), Positives = 104/248 (41%), Gaps = 33/248 (13%)
Query: 786 EESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLR 845
+ES Q + D +D Q + E TE + + + E+R K
Sbjct: 57 QESPRSWGLGQAHKDADGDDRQRERDRVR---------EKTEKERDRDRKRDRERRRK-- 105
Query: 846 EIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKL 905
E E+ + + Q+ E+ + R+K RE+E++ RERERD +D+EK
Sbjct: 106 -----------EKETNRNRDREKQTEIER-DREREKQKGRERERDRGRERERD-RDREK- 151
Query: 906 ESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKESS 965
E + +K++D T ER+R R + R + + ER +++R E
Sbjct: 152 ERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDR---ERD 208
Query: 966 RSRSSHKDSPRDVSKKAKRSPSGSRTPKRSR-----RSRSRSPKKSGKKSRSQSRSPHRS 1020
R R + + R+ ++ +R R +R R R R R K+ KK R + R R
Sbjct: 209 RQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERK 268
Query: 1021 HKKSKKNK 1028
KK ++ +
Sbjct: 269 EKKKEEKR 276
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 71.6 bits (174), Expect = 4e-12
Identities = 87/322 (27%), Positives = 137/322 (42%), Gaps = 58/322 (18%)
Query: 760 KWEAVDESELEAQAVTTSKWELFDQHE-ESEEEENQNQEEESEDEEDTQSSKSEEHHLYS 818
K E + + ++E + + + K + D+ + + EE+E+ ++ E + S+S S
Sbjct: 127 KKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRS 186
Query: 819 NPIKEEM-----------TESKFSKYSEMSEEKRAKLREIELKVMK--FQDELESGKRPK 865
+P++ E T+S+ + +EK +L E +KV + Q+ + K
Sbjct: 187 SPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILK 246
Query: 866 KPG-QSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKLESRSKDKKEKDECT-PTRK 923
P + E E +K ++EKEKE R R R + +SRS+ + T P R+
Sbjct: 247 VPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRS-----KSRSRTRSRSPSHTRPRRR 301
Query: 924 ERKRRHSTSP----SPSRSSSGRRV----KSPSPKSERSERS--------------ERSH 961
R R S SP SP R S RR + P P R RS S
Sbjct: 302 HRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSS 361
Query: 962 KESSRSRSSHKDSPRDVS----KKAKRSPSGSRTPKRSRRS----------RSRSPKKSG 1007
SSRSRS K P+ S K + SPS S +R R S S +P++S
Sbjct: 362 SSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSN 421
Query: 1008 KKSRSQ-SRSPHRSHKKSKKNK 1028
+ +S+ S SP R+ K K+K
Sbjct: 422 RTRKSRVSVSPGRTSGKVTKHK 443
Score = 67.0 bits (162), Expect = 9e-11
Identities = 56/198 (28%), Positives = 88/198 (44%), Gaps = 43/198 (21%)
Query: 870 SFQEQVEHYRDKLLQREKEKELERERERDKKDKEKLESRSKDKKEKDECTPTRKER---- 925
S QE + L+ +KE+ +R+ E++K K + KDK++K+E +R++R
Sbjct: 111 SAQENIAGIPSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSR 170
Query: 926 --KRRHSTSPSPSRSSSGRR----------------VKSPSPKSERSERSERSHKESSRS 967
+RR S SPSP R SS R +SPSP E+ E++ + S +
Sbjct: 171 SPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKV 230
Query: 968 RS---SHKDSPRDVSKKAKRSP----------SGSRTPKRSRRSRSRSPKKSGKKSRSQS 1014
+ S D+ K K P S+ K ++R RS +S +SR++S
Sbjct: 231 KEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRS 290
Query: 1015 RSP--------HRSHKKS 1024
RSP HRS +S
Sbjct: 291 RSPSHTRPRRRHRSRSRS 308
Score = 66.2 bits (160), Expect = 1e-10
Identities = 53/190 (27%), Positives = 88/190 (46%), Gaps = 25/190 (13%)
Query: 858 LESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKLESRSKDKKE--K 915
LE K K Q QE++ + + ++K + E+E R+K+++ + R K + +
Sbjct: 124 LELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPR 183
Query: 916 DECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKESSRSRS---SHK 972
+P R+ERKR HS SP S +SPSP E+ E++ + S + +
Sbjct: 184 RRSSPVRRERKRSHSRSPRHRTKS-----RSPSPAPEKKEKTPELPEPSVKVKEPSVQEA 238
Query: 973 DSPRDVSKKAK-------RSPSGSRTPKRSR-------RSRSRSPKKSGKKSRSQSRS-P 1017
S D+ K K + PS + K+ + RSRSRS +S +SRS S + P
Sbjct: 239 TSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRP 298
Query: 1018 HRSHKKSKKN 1027
R H+ ++
Sbjct: 299 RRRHRSRSRS 308
Score = 48.1 bits (113), Expect = 4e-05
Identities = 38/139 (27%), Positives = 59/139 (42%), Gaps = 17/139 (12%)
Query: 886 EKEKELERERERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVK 945
++ ++ R+ ++ D S ++ ++ R+RRHS PSRS+S
Sbjct: 480 QQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHS----PSRSAS----- 530
Query: 946 SPSPKSERSERSERSHKESS------RSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSR 999
PSP+ + E S R + S R R S +P ++ P RTP R R
Sbjct: 531 -PSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRR 589
Query: 1000 SRSPKK-SGKKSRSQSRSP 1017
S SP++ S R S SP
Sbjct: 590 SPSPRRYSPPIQRRYSPSP 608
Score = 47.8 bits (112), Expect = 5e-05
Identities = 77/366 (21%), Positives = 124/366 (33%), Gaps = 99/366 (27%)
Query: 740 PLDATEDSKKN----EPIFKVA-PSKWEAVDESELEAQAVTTSKWELFDQHEESEEEENQ 794
P A E +K EP KV PS EA S++ + K E + +E E+N
Sbjct: 210 PSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDI----LKVPKPEPIPEPKEPSPEKNS 265
Query: 795 NQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLREIELKVMKF 854
+E+E E S+S+ T S+ ++ R++ R +
Sbjct: 266 KKEKEKEKTRPRSRSRSKSR---------SRTRSRSPSHTRPRRRHRSRSRSYSPRRRPS 316
Query: 855 QDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKEL------------ERERERDKKDK 902
S +R + P + H R + R + + R R KK
Sbjct: 317 PRRRPSPRR-RTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPP 375
Query: 903 EKLESRSKDK------------------------KEKDECTPTRKERKRRHSTSPSPSRS 938
++ S + K + TP + R R+ S SP R+
Sbjct: 376 KRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRT 435
Query: 939 SSG---------RRVKSPSPKSERSERSE--------------------------RSHKE 963
S R SP+PK + E SE +S +
Sbjct: 436 SGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSD 495
Query: 964 SSRSRSSHKDSPR-------DVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRS 1016
S S SS + P+ +V ++ + SPS S +P +R + SP+ G++ RS S
Sbjct: 496 SGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPR--GRRRRSPSPP 553
Query: 1017 PHRSHK 1022
P R +
Sbjct: 554 PTRRRR 559
Score = 46.6 bits (109), Expect = 1e-04
Identities = 55/223 (24%), Positives = 86/223 (38%), Gaps = 25/223 (11%)
Query: 808 SSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLREIELKVMKFQDELESGKRPKKP 867
+ K E P K E++ES+ K +M+ + R + + Q +SG
Sbjct: 445 TEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRR-QYRRQNQQSSSDSGSSSSSE 503
Query: 868 GQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKLESRSKDKKEKDECTPTRKERKR 927
+ + + H ++ + R + R + ++K S ++ PTR+ R
Sbjct: 504 DE--RPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRR-- 559
Query: 928 RHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKESSRSRSSHKDSPRDVSKKAKRSPS 987
SPSP+ RR +P P+ R+ R RS SPR S +R S
Sbjct: 560 ----SPSPAPPPRRRRTPTPPPR-------RRTPSPPPRRRS---PSPRRYSPPIQRRYS 605
Query: 988 GSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHR--SHKKSKKNK 1028
S PKR R+ SP K+ S S P R SH K +
Sbjct: 606 PSPPPKR----RTASPPPPPKRRASPSPPPKRRVSHSPPPKQR 644
Score = 46.2 bits (108), Expect = 2e-04
Identities = 65/269 (24%), Positives = 104/269 (38%), Gaps = 48/269 (17%)
Query: 784 QHEESEEEENQN------QEEESEDEED-----TQSSKSEEHHLYSNPIKEEMTESKFSK 832
+H+ +E+ E+ + + E SE EED + ++ Y ++ ++S S
Sbjct: 441 KHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSS 500
Query: 833 YSEMSEEKRAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELE 892
SE KR+ ++ E+ +R P +S + Q+E
Sbjct: 501 SSEDERPKRSHVKNGEV----------GRRRRHSPSRSASPS-----PRKRQKETSPRGR 545
Query: 893 RERERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHST-----SPSPSRSSSG-RRVKS 946
R R + S S + TPT R+R S SPSP R S +R S
Sbjct: 546 RRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYS 605
Query: 947 PSPKSERSERS-------ERSHKESSRSRSSHKDSPRDVSKKA--KRSPSGSRTPKRSRR 997
PSP +R S S + R SH P+ S +RSPS S S+
Sbjct: 606 PSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLS-----SKH 660
Query: 998 SRSRSPKKSGKKSRSQSRSPHRSHKKSKK 1026
+ SP +S +++RS P++ H S +
Sbjct: 661 RKGSSPSRSTREARSPQ--PNKRHSPSPR 687
Score = 45.8 bits (107), Expect = 2e-04
Identities = 40/131 (30%), Positives = 60/131 (45%), Gaps = 9/131 (6%)
Query: 903 EKLESRSKDKKEKDECTPTRKERKRRHSTSPSPS---RSSSGRRVK-SPSPKSERSERSE 958
++ +S S + + T + +K + + SPSP R SS R V SP P +++
Sbjct: 709 QRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPP 768
Query: 959 RSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSR-SP 1017
+ S S + SP KKAK SP+ S +P R+ KK KK + +
Sbjct: 769 SPVQSQSPSTNW---SPAVPVKKAK-SPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKK 824
Query: 1018 HRSHKKSKKNK 1028
H+ HKK KK K
Sbjct: 825 HKKHKKHKKEK 835
Score = 45.1 bits (105), Expect = 4e-04
Identities = 52/208 (25%), Positives = 85/208 (40%), Gaps = 44/208 (21%)
Query: 862 KRPKKPGQSFQEQVEH-----YRDKLLQREKEKELE-RERERDKKDKEKLESRSKDKKEK 915
KR P + +V H R + + + L + R+ + E+RS ++
Sbjct: 622 KRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKR 681
Query: 916 DECTPTRKERKRRHSTSPSPSR---SSSGRRVKSPSPKSERSERSERSHKESSRSRSSHK 972
+P+ + R + S+SP P R SSS +R +SPSP + R R+ E + + +
Sbjct: 682 H--SPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRT-PEPKKIKKAAS 738
Query: 973 DSPRDVSK-KAKRSPSGSRTPKRSRRSRSRSPKKSG------------KKSRSQSRSP-- 1017
SP+ V + + RS SGS P + SP +S KK++S + SP
Sbjct: 739 PSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSP 798
Query: 1018 -----------------HRSHKKSKKNK 1028
+ HKK KK+K
Sbjct: 799 PRNSDQEGGGKKKKKKKDKKHKKDKKHK 826
Score = 43.9 bits (102), Expect = 8e-04
Identities = 41/149 (27%), Positives = 66/149 (44%), Gaps = 17/149 (11%)
Query: 881 KLLQREKEKELERERERDKKDKEKLESRSKDKKEK---DECTPTRKERKRRHSTSPSPSR 937
K+ + + ++ E K K +L +DK K + R++ +R++ S S S
Sbjct: 438 KVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSG 497
Query: 938 SSSGRRVKSPSPKSERSERSERSHKESSRSRS---SHKDSPRDVSKKAKRSPSGSR---- 990
SSS S + ER +RS + E R R S SP ++ + SP G R
Sbjct: 498 SSS-------SSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSP 550
Query: 991 TPKRSRRSRSRSPKKSGKKSRSQSRSPHR 1019
+P +RR RS SP ++ R+ + P R
Sbjct: 551 SPPPTRRRRSPSPAPPPRRRRTPTPPPRR 579
Score = 43.9 bits (102), Expect = 8e-04
Identities = 39/137 (28%), Positives = 57/137 (41%), Gaps = 6/137 (4%)
Query: 894 ERERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSER 953
+R K + S K +P+ ++R + P RSS + +SPS S+
Sbjct: 601 QRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKH 660
Query: 954 SERS--ERSHKE--SSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKK 1009
+ S RS +E S + H SPR + + SP R S R +SP S +
Sbjct: 661 RKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRP 720
Query: 1010 SRSQSRSPHRSHKKSKK 1026
R SR+P KK KK
Sbjct: 721 IRRVSRTP--EPKKIKK 735
Score = 33.1 bits (74), Expect = 1.4
Identities = 24/73 (32%), Positives = 41/73 (56%), Gaps = 7/73 (9%)
Query: 185 IETKKPPLKKGEKEKKKSNLELFKEELKQIQEERDERHKTKGRLSRFEPPQSDSDGQRRS 244
+E KK +K+ + E++K +K+ E++D+R K + SR + +S S +R+S
Sbjct: 124 LELKKEEIKQRQIEQEKL------ASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKS 177
Query: 245 MDAPSRRNRSSGV 257
+PS R RSS V
Sbjct: 178 R-SPSPRRRSSPV 189
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.128 0.362
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,789,970
Number of Sequences: 37866
Number of extensions: 2456114
Number of successful extensions: 51820
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 868
Number of HSP's successfully gapped in prelim test: 1588
Number of HSP's that attempted gapping in prelim test: 17270
Number of HSP's gapped (non-prelim): 17608
length of query: 1029
length of database: 18,247,518
effective HSP length: 112
effective length of query: 917
effective length of database: 14,006,526
effective search space: 12843984342
effective search space used: 12843984342
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.