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Search of human proteins with 122937211
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|122937211 KIAA0368 protein [Homo sapiens]
(2017 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|122937211 KIAA0368 protein [Homo sapiens] 3961 0.0
gi|54607053 GCN1 general control of amino-acid synthesis 1-like ... 59 5e-08
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 48 1e-04
gi|158854042 hypothetical protein LOC222183 [Homo sapiens] 43 0.004
gi|169204521 PREDICTED: hypothetical protein [Homo sapiens] 42 0.008
gi|169205149 PREDICTED: hypothetical protein [Homo sapiens] 42 0.008
gi|169204400 PREDICTED: hypothetical protein [Homo sapiens] 42 0.008
gi|23510381 transportin 1 isoform 2 [Homo sapiens] 41 0.014
gi|133925811 transportin 1 isoform 1 [Homo sapiens] 41 0.014
gi|42821110 hypothetical protein LOC340602 [Homo sapiens] 41 0.014
gi|24307963 zinc finger, DHHC-type containing 1 [Homo sapiens] 40 0.018
gi|239753673 PREDICTED: hypothetical protein [Homo sapiens] 39 0.052
gi|209969838 transportin 2 (importin 3, karyopherin beta 2b) iso... 39 0.052
gi|209969836 transportin 2 (importin 3, karyopherin beta 2b) iso... 39 0.052
gi|48675813 transportin 2 (importin 3, karyopherin beta 2b) isof... 39 0.052
gi|62460637 importin 4 [Homo sapiens] 39 0.052
gi|239756987 PREDICTED: hypothetical protein XP_002345138 [Homo ... 39 0.067
gi|239746003 PREDICTED: hypothetical protein XP_002344191 [Homo ... 39 0.067
gi|239741585 PREDICTED: hypothetical protein XP_002342243 [Homo ... 39 0.067
gi|239754468 PREDICTED: hypothetical protein [Homo sapiens] 38 0.088
gi|239749023 PREDICTED: hypothetical protein XP_002346884 [Homo ... 38 0.088
gi|239746609 PREDICTED: hypothetical protein XP_002343799 [Homo ... 38 0.088
gi|239743042 PREDICTED: hypothetical protein XP_002342725 [Homo ... 38 0.088
gi|239754081 PREDICTED: hypothetical protein XP_002345876 [Homo ... 38 0.11
gi|239751123 PREDICTED: hypothetical protein XP_002347725 [Homo ... 38 0.11
gi|239748667 PREDICTED: hypothetical protein XP_002346761 [Homo ... 38 0.11
gi|239742692 PREDICTED: hypothetical protein XP_002342583 [Homo ... 38 0.11
gi|238624195 hypothetical protein LOC221545 isoform 3 [Homo sapi... 37 0.15
gi|239753399 PREDICTED: hypothetical protein [Homo sapiens] 37 0.20
gi|239741865 PREDICTED: hypothetical protein XP_002342328 [Homo ... 37 0.20
>gi|122937211 KIAA0368 protein [Homo sapiens]
Length = 2017
Score = 3961 bits (10272), Expect = 0.0
Identities = 2017/2017 (100%), Positives = 2017/2017 (100%)
Query: 1 MTSRTKRRQKVKISISKINHSSYRKEHRPFWEHQPPPHQNWAVGGRCGAGARPGLSQRRG 60
MTSRTKRRQKVKISISKINHSSYRKEHRPFWEHQPPPHQNWAVGGRCGAGARPGLSQRRG
Sbjct: 1 MTSRTKRRQKVKISISKINHSSYRKEHRPFWEHQPPPHQNWAVGGRCGAGARPGLSQRRG 60
Query: 61 REVRREAQGGASSRRLRARLYFSESTSLPLDRRGSPGPLGPAPHGLRRAAPRGPARRTPR 120
REVRREAQGGASSRRLRARLYFSESTSLPLDRRGSPGPLGPAPHGLRRAAPRGPARRTPR
Sbjct: 61 REVRREAQGGASSRRLRARLYFSESTSLPLDRRGSPGPLGPAPHGLRRAAPRGPARRTPR 120
Query: 121 STALTSRRRAQRPRHGDRLRLRSEARPRAAGDWPCARGGAVRPGRPHRPPRVESARGAHA 180
STALTSRRRAQRPRHGDRLRLRSEARPRAAGDWPCARGGAVRPGRPHRPPRVESARGAHA
Sbjct: 121 STALTSRRRAQRPRHGDRLRLRSEARPRAAGDWPCARGGAVRPGRPHRPPRVESARGAHA 180
Query: 181 GRAATDQLERVFLRLGHAETDEQLQNIISKFLPPVLLKLSSTQEGVRKKVMELLVHLNKR 240
GRAATDQLERVFLRLGHAETDEQLQNIISKFLPPVLLKLSSTQEGVRKKVMELLVHLNKR
Sbjct: 181 GRAATDQLERVFLRLGHAETDEQLQNIISKFLPPVLLKLSSTQEGVRKKVMELLVHLNKR 240
Query: 241 IKSRPKIQLPVETLLVQYQDPAAVSFVTNFTIIYVKMGYPRLPVEKQCELAPTLLTAMEG 300
IKSRPKIQLPVETLLVQYQDPAAVSFVTNFTIIYVKMGYPRLPVEKQCELAPTLLTAMEG
Sbjct: 241 IKSRPKIQLPVETLLVQYQDPAAVSFVTNFTIIYVKMGYPRLPVEKQCELAPTLLTAMEG 300
Query: 301 KPQPQQDSLMHLLIPTLFHMKYPVESSKSASPFNLAEKPKTVQLLLDFMLDVLLMPYGYV 360
KPQPQQDSLMHLLIPTLFHMKYPVESSKSASPFNLAEKPKTVQLLLDFMLDVLLMPYGYV
Sbjct: 301 KPQPQQDSLMHLLIPTLFHMKYPVESSKSASPFNLAEKPKTVQLLLDFMLDVLLMPYGYV 360
Query: 361 LNESQSRQNSSSAQGSSSNSGGGSGIPQPPPGMSFYAAKRVIGDNPWTPEQLEQCKLGIV 420
LNESQSRQNSSSAQGSSSNSGGGSGIPQPPPGMSFYAAKRVIGDNPWTPEQLEQCKLGIV
Sbjct: 361 LNESQSRQNSSSAQGSSSNSGGGSGIPQPPPGMSFYAAKRVIGDNPWTPEQLEQCKLGIV 420
Query: 421 KFIEAEQVPELEAVLHLVIASSDTRHSVATAADLELKSKQSLIDWNNPAIINKMYKVYLG 480
KFIEAEQVPELEAVLHLVIASSDTRHSVATAADLELKSKQSLIDWNNPAIINKMYKVYLG
Sbjct: 421 KFIEAEQVPELEAVLHLVIASSDTRHSVATAADLELKSKQSLIDWNNPAIINKMYKVYLG 480
Query: 481 DIPLKTKEGAVLKPELKRDPVSTRVKLKIVPHLLRSRQAAETFPANIQVVYDGLFGTNTN 540
DIPLKTKEGAVLKPELKRDPVSTRVKLKIVPHLLRSRQAAETFPANIQVVYDGLFGTNTN
Sbjct: 481 DIPLKTKEGAVLKPELKRDPVSTRVKLKIVPHLLRSRQAAETFPANIQVVYDGLFGTNTN 540
Query: 541 SKLRTLSLQFVHHICITCPEIKIKPLGPMLLNGLTKLINEYKEDPKLLSMAYSAVGKLSS 600
SKLRTLSLQFVHHICITCPEIKIKPLGPMLLNGLTKLINEYKEDPKLLSMAYSAVGKLSS
Sbjct: 541 SKLRTLSLQFVHHICITCPEIKIKPLGPMLLNGLTKLINEYKEDPKLLSMAYSAVGKLSS 600
Query: 601 RMPHLFTKDIALVQQLFEALCKEEPETRLAIQEALSMMVGAYSTLEGAQRTLMEALVASY 660
RMPHLFTKDIALVQQLFEALCKEEPETRLAIQEALSMMVGAYSTLEGAQRTLMEALVASY
Sbjct: 601 RMPHLFTKDIALVQQLFEALCKEEPETRLAIQEALSMMVGAYSTLEGAQRTLMEALVASY 660
Query: 661 LIKPEVQVRQVAVKFASTVFPSDHIPSRYLLLLAAGDPREEVHGEAQRVLRCLPGRNRKE 720
LIKPEVQVRQVAVKFASTVFPSDHIPSRYLLLLAAGDPREEVHGEAQRVLRCLPGRNRKE
Sbjct: 661 LIKPEVQVRQVAVKFASTVFPSDHIPSRYLLLLAAGDPREEVHGEAQRVLRCLPGRNRKE 720
Query: 721 STSEQMPSFPEMVYYIQEKASHRMKTPVKYMTGTTVLPFNPAAFGEIVLYLRMCLAHSAG 780
STSEQMPSFPEMVYYIQEKASHRMKTPVKYMTGTTVLPFNPAAFGEIVLYLRMCLAHSAG
Sbjct: 721 STSEQMPSFPEMVYYIQEKASHRMKTPVKYMTGTTVLPFNPAAFGEIVLYLRMCLAHSAG 780
Query: 781 VVPTSQSLADMQDHAPAIGRYIRTLMSSGQMAPSSSNKSGETNPVQIYIGLLQQLLAGVG 840
VVPTSQSLADMQDHAPAIGRYIRTLMSSGQMAPSSSNKSGETNPVQIYIGLLQQLLAGVG
Sbjct: 781 VVPTSQSLADMQDHAPAIGRYIRTLMSSGQMAPSSSNKSGETNPVQIYIGLLQQLLAGVG 840
Query: 841 GLPVMYCLLEAVSVYPEKLATKFVDKTEWIKSLMNNSKEEMRELAALFYSVVVSTVSGNE 900
GLPVMYCLLEAVSVYPEKLATKFVDKTEWIKSLMNNSKEEMRELAALFYSVVVSTVSGNE
Sbjct: 841 GLPVMYCLLEAVSVYPEKLATKFVDKTEWIKSLMNNSKEEMRELAALFYSVVVSTVSGNE 900
Query: 901 LKSMIEQLIKTTKDNHSPEIQHGSLLALGFTVGRYLAKKKMRMSEQQDLERNADTLPDQE 960
LKSMIEQLIKTTKDNHSPEIQHGSLLALGFTVGRYLAKKKMRMSEQQDLERNADTLPDQE
Sbjct: 901 LKSMIEQLIKTTKDNHSPEIQHGSLLALGFTVGRYLAKKKMRMSEQQDLERNADTLPDQE 960
Query: 961 ELIQSATETIGSFLDSTSPLLAIAACTALGEIGRNGPLPIPSEGSGFTKLHLVESLLSRI 1020
ELIQSATETIGSFLDSTSPLLAIAACTALGEIGRNGPLPIPSEGSGFTKLHLVESLLSRI
Sbjct: 961 ELIQSATETIGSFLDSTSPLLAIAACTALGEIGRNGPLPIPSEGSGFTKLHLVESLLSRI 1020
Query: 1021 PSSKETNKMKERAIQTLGYFPVGDGDFPHQKLLLQGLMDSVEAKQIELQFTIGEAITSAA 1080
PSSKETNKMKERAIQTLGYFPVGDGDFPHQKLLLQGLMDSVEAKQIELQFTIGEAITSAA
Sbjct: 1021 PSSKETNKMKERAIQTLGYFPVGDGDFPHQKLLLQGLMDSVEAKQIELQFTIGEAITSAA 1080
Query: 1081 IGTSSVAARDAWQMTEEEYTPPAGAKVNDVVPWVLDVILNKHIISPNPHVRQAACIWLLS 1140
IGTSSVAARDAWQMTEEEYTPPAGAKVNDVVPWVLDVILNKHIISPNPHVRQAACIWLLS
Sbjct: 1081 IGTSSVAARDAWQMTEEEYTPPAGAKVNDVVPWVLDVILNKHIISPNPHVRQAACIWLLS 1140
Query: 1141 LVRKLSTHKEVKSHLKEIQSAFVSVLSENDELSQDVASKGLGLVYELGNEQDQQELVSTL 1200
LVRKLSTHKEVKSHLKEIQSAFVSVLSENDELSQDVASKGLGLVYELGNEQDQQELVSTL
Sbjct: 1141 LVRKLSTHKEVKSHLKEIQSAFVSVLSENDELSQDVASKGLGLVYELGNEQDQQELVSTL 1200
Query: 1201 VETLMTGKRVKHEVSGETVVFQGGALGKTPDGQGLSTYKELCSLASDLSQPDLVYKFMNL 1260
VETLMTGKRVKHEVSGETVVFQGGALGKTPDGQGLSTYKELCSLASDLSQPDLVYKFMNL
Sbjct: 1201 VETLMTGKRVKHEVSGETVVFQGGALGKTPDGQGLSTYKELCSLASDLSQPDLVYKFMNL 1260
Query: 1261 ANHHAMWNSRKGAAFGFNVIATRAGEQLAPFLPQLVPRLYRYQFDPNLGIRQAMTSIWNA 1320
ANHHAMWNSRKGAAFGFNVIATRAGEQLAPFLPQLVPRLYRYQFDPNLGIRQAMTSIWNA
Sbjct: 1261 ANHHAMWNSRKGAAFGFNVIATRAGEQLAPFLPQLVPRLYRYQFDPNLGIRQAMTSIWNA 1320
Query: 1321 LVTDKSMVDKYLKEILQDLVKNLTSNMWRVRESSCLALNDLLRGRPLDDIIDKLPEIWET 1380
LVTDKSMVDKYLKEILQDLVKNLTSNMWRVRESSCLALNDLLRGRPLDDIIDKLPEIWET
Sbjct: 1321 LVTDKSMVDKYLKEILQDLVKNLTSNMWRVRESSCLALNDLLRGRPLDDIIDKLPEIWET 1380
Query: 1381 LFRVQDDIKESVRKAAELALKTLSKVCVKMCDPAKGAAGQRTIAALLPCLLDKGMMSTVT 1440
LFRVQDDIKESVRKAAELALKTLSKVCVKMCDPAKGAAGQRTIAALLPCLLDKGMMSTVT
Sbjct: 1381 LFRVQDDIKESVRKAAELALKTLSKVCVKMCDPAKGAAGQRTIAALLPCLLDKGMMSTVT 1440
Query: 1441 EVRALSINTLVKISKSAGAMLKPHAPKLIPALLESLSVLEPQVLNYLSLRATEQEKAAMD 1500
EVRALSINTLVKISKSAGAMLKPHAPKLIPALLESLSVLEPQVLNYLSLRATEQEKAAMD
Sbjct: 1441 EVRALSINTLVKISKSAGAMLKPHAPKLIPALLESLSVLEPQVLNYLSLRATEQEKAAMD 1500
Query: 1501 SARLSAAKSSPMMETINMCLQYLDVSVLGELVPRLCELIRSGVGLGTKGGCASVIVSLTT 1560
SARLSAAKSSPMMETINMCLQYLDVSVLGELVPRLCELIRSGVGLGTKGGCASVIVSLTT
Sbjct: 1501 SARLSAAKSSPMMETINMCLQYLDVSVLGELVPRLCELIRSGVGLGTKGGCASVIVSLTT 1560
Query: 1561 QCPQDLTPYSGKLMSALLSGLTDRNSVIQKSCAFAMGHLVRTSRDSSTEKLLQKLNGWYM 1620
QCPQDLTPYSGKLMSALLSGLTDRNSVIQKSCAFAMGHLVRTSRDSSTEKLLQKLNGWYM
Sbjct: 1561 QCPQDLTPYSGKLMSALLSGLTDRNSVIQKSCAFAMGHLVRTSRDSSTEKLLQKLNGWYM 1620
Query: 1621 EKEEPIYKTSCALTIHAIGRYSPDVLKNHAKEVLPLAFLGMHEIADEEKSEKEECNLWTE 1680
EKEEPIYKTSCALTIHAIGRYSPDVLKNHAKEVLPLAFLGMHEIADEEKSEKEECNLWTE
Sbjct: 1621 EKEEPIYKTSCALTIHAIGRYSPDVLKNHAKEVLPLAFLGMHEIADEEKSEKEECNLWTE 1680
Query: 1681 VWQENVPGSFGGIRLYLQELITITQKALQSQSWKMKAQGAIAMASIAKQTSSLVPPYLGM 1740
VWQENVPGSFGGIRLYLQELITITQKALQSQSWKMKAQGAIAMASIAKQTSSLVPPYLGM
Sbjct: 1681 VWQENVPGSFGGIRLYLQELITITQKALQSQSWKMKAQGAIAMASIAKQTSSLVPPYLGM 1740
Query: 1741 ILTALLQGLAGRTWAGKEELLKAIACVVTACSAELEKSVPNQPSTNEILQAVLKECSKEN 1800
ILTALLQGLAGRTWAGKEELLKAIACVVTACSAELEKSVPNQPSTNEILQAVLKECSKEN
Sbjct: 1741 ILTALLQGLAGRTWAGKEELLKAIACVVTACSAELEKSVPNQPSTNEILQAVLKECSKEN 1800
Query: 1801 VKYKIVAISCAADILKATKEDRFQEFSNIVIPLIKKNSLESSGVRTTKNEEENEKEKELQ 1860
VKYKIVAISCAADILKATKEDRFQEFSNIVIPLIKKNSLESSGVRTTKNEEENEKEKELQ
Sbjct: 1801 VKYKIVAISCAADILKATKEDRFQEFSNIVIPLIKKNSLESSGVRTTKNEEENEKEKELQ 1860
Query: 1861 LEYLLGAFESLGKAWPRNAETQRCYRQELCKLMCERLKLSTWKVQLGVLQSMNAFFQGLM 1920
LEYLLGAFESLGKAWPRNAETQRCYRQELCKLMCERLKLSTWKVQLGVLQSMNAFFQGLM
Sbjct: 1861 LEYLLGAFESLGKAWPRNAETQRCYRQELCKLMCERLKLSTWKVQLGVLQSMNAFFQGLM 1920
Query: 1921 LLEEEHADPEALAEILLETCKSITYSLENKTYSSVRTEALSVIELLLKKLEESKQWECLT 1980
LLEEEHADPEALAEILLETCKSITYSLENKTYSSVRTEALSVIELLLKKLEESKQWECLT
Sbjct: 1921 LLEEEHADPEALAEILLETCKSITYSLENKTYSSVRTEALSVIELLLKKLEESKQWECLT 1980
Query: 1981 SECRVLLIESLATMEPDSRPELQEKAALLKKTLENLE 2017
SECRVLLIESLATMEPDSRPELQEKAALLKKTLENLE
Sbjct: 1981 SECRVLLIESLATMEPDSRPELQEKAALLKKTLENLE 2017
>gi|54607053 GCN1 general control of amino-acid synthesis 1-like 1
[Homo sapiens]
Length = 2671
Score = 58.9 bits (141), Expect = 5e-08
Identities = 105/554 (18%), Positives = 207/554 (37%), Gaps = 70/554 (12%)
Query: 1107 VNDVVPWVLDVILNKHIISPNPHVRQAACIWLLSLVRKLSTHKEVKSHLKEIQSAFVSVL 1166
VN ++P + + N + VRQ+ + + SL + L + +K I + ++ L
Sbjct: 1292 VNSLLPVFEEFLKNAPNDASYDAVRQSVVVLMGSLAKHLD---KSDPKVKPIVAKLIAAL 1348
Query: 1167 SE-NDELSQDVASKGLGLVYELGNEQDQQELVSTLVETLMTGKRVKHEVSGETVVFQGGA 1225
S + ++ + VAS LV + ++D ++ L++ L+ + +G A
Sbjct: 1349 STPSQQVQESVASCLPPLVPAI--KEDAGGMIQRLMQQLLESDKYAER--------KGAA 1398
Query: 1226 LGKTPDGQGLSTYKELCSLASDLSQPDLVYKFMNLANHHAMWNSRKGAAFGFNVIATRAG 1285
G +GL L Q +++ + + R+GA F F ++ T G
Sbjct: 1399 YGLAGLVKGLGILS--------LKQQEMMAALTDAIQDKKNFRRREGALFAFEMLCTMLG 1450
Query: 1286 EQLAPFLPQLVPRLYRYQFDPNLGIRQAMTSIWNALVTDKSMVDKYLKEILQDLVKNLTS 1345
+ P++ ++P L D N +R+A A++++ S +K +L L+ L
Sbjct: 1451 KLFEPYVVHVLPHLLLCFGDGNQYVREAADDCAKAVMSNLSA--HGVKLVLPSLLAALEE 1508
Query: 1346 NMWRVRESSCLALNDLLRGRPLDDIIDKLPEIWETLFRVQDDIKESVRKAAELALKTLSK 1405
WR + S L + P + LP I L V D V+KA + AL+ +
Sbjct: 1509 ESWRTKAGSVELLGAMAYCAP-KQLSSCLPNIVPKLTEVLTDSHVKVQKAGQQALRQIGS 1567
Query: 1406 VCVK-------------MCDPAKGA---------------AGQRTIAALLPCLLDKGMMS 1437
V + DP++ ++A ++P ++ +
Sbjct: 1568 VIRNPEILAIAPVLLDALTDPSRKTQKCLQTLLDTKFVHFIDAPSLALIMP-IVQRAFQD 1626
Query: 1438 TVTEVRALSINTLVKI-SKSAGAMLKPHAPKLIPALLESLSVLEPQVLNYLSLRATEQEK 1496
T+ R ++ + + S + L P+ P + P L SL P+V + K
Sbjct: 1627 RSTDTRKMAAQIIGNMYSLTDQKDLAPYLPSVTPGLKASLLDPVPEVRTVSAKALGAMVK 1686
Query: 1497 AAMDSA--------------RLSAAKSSPMMETINMCLQYLDVSVLGELVPRL-CELIRS 1541
+S S+ S + + + L V L +L+P + +
Sbjct: 1687 GMGESCFEDLLPWLMETLTYEQSSVDRSGAAQGLAEVMAGLGVEKLEKLMPEIVATASKV 1746
Query: 1542 GVGLGTKGGCASVIVSLTTQCPQDLTPYSGKLMSALLSGLTDRNSVIQKSCAFAMGHLVR 1601
+ + G + L TPY G ++ +L L D N ++ + A ++
Sbjct: 1747 DIAPHVRDGYIMMFNYLPITFGDKFTPYVGPIIPCILKALADENEFVRDTALRAGQRVIS 1806
Query: 1602 TSRDSSTEKLLQKL 1615
+++ LL +L
Sbjct: 1807 MYAETAIALLLPQL 1820
Score = 42.4 bits (98), Expect = 0.005
Identities = 52/224 (23%), Positives = 99/224 (44%), Gaps = 31/224 (13%)
Query: 1145 LSTHKEVKSHLKEIQSAFVSVLSENDELSQDVASKGLGLVYELGNEQDQQELVSTLVETL 1204
L+ K++ +L + + L + + V++K LG + + E ++L+ L+ETL
Sbjct: 1645 LTDQKDLAPYLPSVTPGLKASLLDPVPEVRTVSAKALGAMVKGMGESCFEDLLPWLMETL 1704
Query: 1205 MTGKRVKHEVSGETVVFQGGALGKTPDGQGLSTYKELCSLASDLSQPDLVYKF--MNLAN 1262
T ++ + SG QG L + G G+ ++L P++V +++A
Sbjct: 1705 -TYEQSSVDRSGAA---QG--LAEVMAGLGVEKLEKL--------MPEIVATASKVDIAP 1750
Query: 1263 HHAMWNSRKGAAFGFNVIATRAGEQLAPFLPQLVPRLYRYQFDPNLGIRQAMTSIWNALV 1322
H R G FN + G++ P++ ++P + + D N +R AL
Sbjct: 1751 H-----VRDGYIMMFNYLPITFGDKFTPYVGPIIPCILKALADENEFVRDT------ALR 1799
Query: 1323 TDKSMVDKYLKE----ILQDLVKNLTSNMWRVRESSCLALNDLL 1362
+ ++ Y + +L L + L ++WR+R SS L DLL
Sbjct: 1800 AGQRVISMYAETAIALLLPQLEQGLFDDLWRIRFSSVQLLGDLL 1843
Score = 40.0 bits (92), Expect = 0.023
Identities = 50/235 (21%), Positives = 91/235 (38%), Gaps = 24/235 (10%)
Query: 1125 SPNPHVRQAACIWLLSLVRKLSTHKEVKSHLKEIQSAFVSVLSENDELSQDVASKGLGLV 1184
SP +RQAA I L + + + SHL+ + S + + +++ + + + L +
Sbjct: 2162 SPEVGMRQAAAIILNIYCSR--SKADYTSHLRSLVSGLIRLFNDSSPVVLEESWDALNAI 2219
Query: 1185 YELGNEQDQQELVSTL-VETLMTGKRVKHE-----------VSGETVVFQGGALGKTPD- 1231
+ + +Q L+ L E + G K E V+ V + G L +P+
Sbjct: 2220 TKKLDAGNQLALIEELHKEIRLIGNESKGEHVPGFCLPKKGVTSILPVLREGVLTGSPEQ 2279
Query: 1232 ----GQGLSTYKELCSLASDLSQPDLVY---KFMNLANHHAMWNSRKGAAFGFNVIATRA 1284
+ L L S +D +P +V + + WN + +++ +
Sbjct: 2280 KEEAAKALGLVIRLTS--ADALRPSVVSITGPLIRILGDRFSWNVKAALLETLSLLLAKV 2337
Query: 1285 GEQLAPFLPQLVPRLYRYQFDPNLGIRQAMTSIWNALVTDKSMVDKYLKEILQDL 1339
G L PFLPQL + D N G+R L++ VD E+L +
Sbjct: 2338 GIALKPFLPQLQTTFTKALQDSNRGVRLKAADALGKLISIHIKVDPLFTELLNGI 2392
Score = 33.5 bits (75), Expect = 2.2
Identities = 59/310 (19%), Positives = 120/310 (38%), Gaps = 45/310 (14%)
Query: 1325 KSMVDKYLKEILQDLVKNLTSNMWRVRESSCLALNDLLRGRPLDDIIDKLPEIWETLFRV 1384
+ + +K L EI+ L + L S R+ C+ L+++++ D ++ + T +
Sbjct: 1954 RKLGEKILPEIIPILEEGLRSQKSDERQGVCIGLSEIMKSTSRDAVLYFSESLVPTARKA 2013
Query: 1385 QDDIKESVRKAAELALKTLSKVCVKMCDPAKGAAGQRTIAALLPCLLDKGMMSTVTEVRA 1444
D E VR+AA K + G + + +LP LL + EV
Sbjct: 2014 LCDPLEEVREAA-----------AKTFEQLHSTIGHQALEDILPFLLKQ---LDDEEVSE 2059
Query: 1445 LSINTLVKISKSAGAMLKPH-APKLI-----------------PALLESLSVLEPQVLNY 1486
+++ L ++ ++ P+ PKL AL L V+ P V+
Sbjct: 2060 FALDGLKQVMAIKSRVVLPYLVPKLTTPPVNTRVLAFLSSVAGDALTRHLGVILPAVMLA 2119
Query: 1487 LSLRATEQEKAAMDSARLSAAKSSPMMETINMCLQYLDVSVLGELVPRLCELIRSGVGLG 1546
L +EK +L A ++ ++ D + ++ L E RS +G
Sbjct: 2120 L------KEKLGTPDEQLEMANCQAVILSVE------DDTGHRIIIEDLLEATRS-PEVG 2166
Query: 1547 TKGGCASVIVSLTTQCPQDLTPYSGKLMSALLSGLTDRNSVIQKSCAFAMGHLVRTSRDS 1606
+ A ++ ++ D T + L+S L+ D + V+ + A+ + +
Sbjct: 2167 MRQAAAIILNIYCSRSKADYTSHLRSLVSGLIRLFNDSSPVVLEESWDALNAITKKLDAG 2226
Query: 1607 STEKLLQKLN 1616
+ L+++L+
Sbjct: 2227 NQLALIEELH 2236
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 47.8 bits (112), Expect = 1e-04
Identities = 59/187 (31%), Positives = 72/187 (38%), Gaps = 18/187 (9%)
Query: 4 RTKRRQKVKISISKINHSSYRKEHRPF-WEHQPPPHQNWAVGGRCGAGARPGLS-----Q 57
R++ R K S+ +R+ W P + GR + RPG S Q
Sbjct: 494 RSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRR----GRSRSPQRPGWSRSRNTQ 549
Query: 58 RRGREVRREAQGGASSRRLRARLYFSESTSLPLDRRGSPGPLGPAPHGLRRAAPRGPARR 117
RRGR R A+ G S R A S S RRG PA RR+ R P RR
Sbjct: 550 RRGRS--RSARRGRSHSRSPATR--GRSRSRTPARRGRSRSRTPAR---RRSRSRTPTRR 602
Query: 118 TPRSTALTSRRRAQ-RPRHGDRLRLRSEARPRAAGDWPCARGGAVRPGRPHRPPRVESAR 176
RS R R++ R R R RS R R+ P R G R P R R S
Sbjct: 603 RSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRT 662
Query: 177 GAHAGRA 183
A GR+
Sbjct: 663 PARRGRS 669
Score = 37.7 bits (86), Expect = 0.11
Identities = 59/208 (28%), Positives = 74/208 (35%), Gaps = 34/208 (16%)
Query: 4 RTKRRQKVKISISKINHSSYRKEHRPFWEHQPPPHQNWAVGGRCGAGARPGLSQRRGREV 63
R++ Q+ S S R RP W +N GR AR G S R
Sbjct: 515 RSRSAQRWGRSRSPQRRGRSRSPQRPGWSRS----RNTQRRGR-SRSARRGRSHSRSPAT 569
Query: 64 RREAQGGASSRRLRARLYFS-------------ESTSLPLDRRGSPGPLGPAPHGLRRAA 110
R ++ +RR R+R S S RRG PA R +
Sbjct: 570 RGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRS 629
Query: 111 P-------RGPARRTPRSTALTSRRRAQRPRHGDRLRLRSEA-RPRAAGDWPCARGGAVR 162
P R PARR+ RS + T RR R R R+ A R R+ P R G R
Sbjct: 630 PVRRRSRSRSPARRSGRSRSRTPARRG-------RSRSRTPARRGRSRSRTPARRSGRSR 682
Query: 163 PGRPHRPPRVESARGAHAGRAATDQLER 190
P R R S R GR+ + L R
Sbjct: 683 SRTPARRGRSRS-RTPRRGRSRSRSLVR 709
Score = 35.4 bits (80), Expect = 0.57
Identities = 37/106 (34%), Positives = 45/106 (42%), Gaps = 12/106 (11%)
Query: 52 RPGLSQRRGREVRREAQGGASSRRLRARLYFSESTSLPLDRRGSPGP-------LGPAPH 104
R G S R R+ SSRR R R ++ R SP P PA H
Sbjct: 1814 RRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATH 1873
Query: 105 GLRRAAPRGP--ARRTPRS-TALTSRRRAQRPRHGDRLRLRSEARP 147
RR+ R P +RR RS T+ SRRR++ R R RS A P
Sbjct: 1874 --RRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASP 1917
Score = 32.3 bits (72), Expect = 4.8
Identities = 28/92 (30%), Positives = 42/92 (45%), Gaps = 4/92 (4%)
Query: 56 SQRRGREVRREAQGGASSRRLRARLYFSESTS-LPLDRRGSPGPLGPAPHGLRRAAPRGP 114
S R E+ R+A+ SRR R+ E+ S P R SP P P R++ R
Sbjct: 1690 SSRSSPELTRKAR---LSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRR 1746
Query: 115 ARRTPRSTALTSRRRAQRPRHGDRLRLRSEAR 146
+ +PR+ + R R+ P+ R RS +R
Sbjct: 1747 SASSPRTKTTSRRGRSPSPKPRGLQRSRSRSR 1778
>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
Length = 653
Score = 42.7 bits (99), Expect = 0.004
Identities = 52/191 (27%), Positives = 71/191 (37%), Gaps = 40/191 (20%)
Query: 32 EHQPPPHQNWAVGGRCGAGARPGLSQRRGREVRREAQGGASSRRLRAR------------ 79
+ P P + GR G A +RR R RR ++ AS+ R R R
Sbjct: 361 KESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSS 420
Query: 80 --LYFSESTSLPLDRRGSPGPLGPAP--------HGLRRAAPRGPARRTPRSTA------ 123
L + S+S RG+PGP GP P HG R A P R P ST+
Sbjct: 421 RSLSRARSSSDSGSGRGAPGP-GPEPGSERGHGGHGKR--AKERPPRARPASTSPSPGAH 477
Query: 124 ---------LTSRRRAQRPRHGDRLRLRSEARPRAAGDWPCARGGAVRPGRPHRPPRVES 174
+SR PR R S++R R+A P + + P +P +
Sbjct: 478 GRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGE 537
Query: 175 ARGAHAGRAAT 185
R H+ AT
Sbjct: 538 GRARHSEAEAT 548
>gi|169204521 PREDICTED: hypothetical protein [Homo sapiens]
Length = 430
Score = 41.6 bits (96), Expect = 0.008
Identities = 53/152 (34%), Positives = 60/152 (39%), Gaps = 30/152 (19%)
Query: 45 GRCGAGARPGLSQRRGRE----VRREAQGGASSRRLRARLYFSESTSLPLDRRGSPGPLG 100
G G R + +R+GRE RR QG A+ R S ST P +RG+ GPLG
Sbjct: 227 GSLERGERARIRERKGREGPSRPRRGLQGTAAGRVRADPDDASLSTDKP--QRGTGGPLG 284
Query: 101 PAPHGL----------------RRAAPRGPARRTPRSTALTSR---RRAQRPR-HGDRLR 140
PA G A PRG A P + R R QR R H R R
Sbjct: 285 PAAAGAGTEAAAAHEEGSKAGDSGAEPRGLAPHGPHPSCGERRPGGRWQQRRRSHEGRAR 344
Query: 141 LRSEARPRAAGDWPCA---RGGAVRP-GRPHR 168
R AA P A R G RP GR HR
Sbjct: 345 GRHRVEADAADAAPTAAARRAGRARPRGRRHR 376
>gi|169205149 PREDICTED: hypothetical protein [Homo sapiens]
Length = 430
Score = 41.6 bits (96), Expect = 0.008
Identities = 53/152 (34%), Positives = 60/152 (39%), Gaps = 30/152 (19%)
Query: 45 GRCGAGARPGLSQRRGRE----VRREAQGGASSRRLRARLYFSESTSLPLDRRGSPGPLG 100
G G R + +R+GRE RR QG A+ R S ST P +RG+ GPLG
Sbjct: 227 GSLERGERARIRERKGREGPSRPRRGLQGTAAGRVRADPDDASLSTDKP--QRGTGGPLG 284
Query: 101 PAPHGL----------------RRAAPRGPARRTPRSTALTSR---RRAQRPR-HGDRLR 140
PA G A PRG A P + R R QR R H R R
Sbjct: 285 PAAAGAGTEAAAAHEEGSKAGDSGAEPRGLAPHGPHPSCGERRPGGRWQQRRRSHEGRAR 344
Query: 141 LRSEARPRAAGDWPCA---RGGAVRP-GRPHR 168
R AA P A R G RP GR HR
Sbjct: 345 GRHRVEADAADAAPTAAARRAGRARPRGRRHR 376
>gi|169204400 PREDICTED: hypothetical protein [Homo sapiens]
Length = 430
Score = 41.6 bits (96), Expect = 0.008
Identities = 53/152 (34%), Positives = 60/152 (39%), Gaps = 30/152 (19%)
Query: 45 GRCGAGARPGLSQRRGRE----VRREAQGGASSRRLRARLYFSESTSLPLDRRGSPGPLG 100
G G R + +R+GRE RR QG A+ R S ST P +RG+ GPLG
Sbjct: 227 GSLERGERARIRERKGREGPSRPRRGLQGTAAGRVRADPDDASLSTDKP--QRGTGGPLG 284
Query: 101 PAPHGL----------------RRAAPRGPARRTPRSTALTSR---RRAQRPR-HGDRLR 140
PA G A PRG A P + R R QR R H R R
Sbjct: 285 PAAAGAGTEAAAAHEEGSKAGDSGAEPRGLAPHGPHPSCGERRPGGRWQQRRRSHEGRAR 344
Query: 141 LRSEARPRAAGDWPCA---RGGAVRP-GRPHR 168
R AA P A R G RP GR HR
Sbjct: 345 GRHRVEADAADAAPTAAARRAGRARPRGRRHR 376
>gi|23510381 transportin 1 isoform 2 [Homo sapiens]
Length = 890
Score = 40.8 bits (94), Expect = 0.014
Identities = 35/145 (24%), Positives = 63/145 (43%), Gaps = 8/145 (5%)
Query: 1241 LCSLASDLSQPDLVYKFMNLANHHAMWNSRKGAAFGFNVIATRAGEQLAPFLPQLVPRLY 1300
L ++ D P ++ L HH W ++ IA + + P+LP+L+P L
Sbjct: 386 LANVYRDELLPHILPLLKELLFHHE-WVVKESGILVLGAIAEGCMQGMIPYLPELIPHLI 444
Query: 1301 RYQFDPNLGIRQAMTSIWNALVTDKSMV----DKYLKEILQDLVKNLTSNMWRVRESSCL 1356
+ D +R + W +V D YLK ++ +L+K + + RV+E++C
Sbjct: 445 QCLSDKKALVRSI--TCWTLSRYAHWVVSQPPDTYLKPLMTELLKRILDSNKRVQEAACS 502
Query: 1357 ALNDLLRGRPLDDIIDKLPEIWETL 1381
A L +++ L I +TL
Sbjct: 503 AF-ATLEEEACTELVPYLAYILDTL 526
Score = 35.8 bits (81), Expect = 0.44
Identities = 26/118 (22%), Positives = 52/118 (44%), Gaps = 5/118 (4%)
Query: 1697 LQELITITQKALQSQSWKMKAQGAIAMASIAKQTSSLVPPYLGMILTALLQGLAGRTWAG 1756
L ++ + ++ L W +K G + + +IA+ + PYL ++ L+Q L +
Sbjct: 395 LPHILPLLKELLFHHEWVVKESGILVLGAIAEGCMQGMIPYLPELIPHLIQCL-----SD 449
Query: 1757 KEELLKAIACVVTACSAELEKSVPNQPSTNEILQAVLKECSKENVKYKIVAISCAADI 1814
K+ L+++I C + A S P ++ +LK N + + A S A +
Sbjct: 450 KKALVRSITCWTLSRYAHWVVSQPPDTYLKPLMTELLKRILDSNKRVQEAACSAFATL 507
>gi|133925811 transportin 1 isoform 1 [Homo sapiens]
Length = 898
Score = 40.8 bits (94), Expect = 0.014
Identities = 35/145 (24%), Positives = 63/145 (43%), Gaps = 8/145 (5%)
Query: 1241 LCSLASDLSQPDLVYKFMNLANHHAMWNSRKGAAFGFNVIATRAGEQLAPFLPQLVPRLY 1300
L ++ D P ++ L HH W ++ IA + + P+LP+L+P L
Sbjct: 394 LANVYRDELLPHILPLLKELLFHHE-WVVKESGILVLGAIAEGCMQGMIPYLPELIPHLI 452
Query: 1301 RYQFDPNLGIRQAMTSIWNALVTDKSMV----DKYLKEILQDLVKNLTSNMWRVRESSCL 1356
+ D +R + W +V D YLK ++ +L+K + + RV+E++C
Sbjct: 453 QCLSDKKALVRSI--TCWTLSRYAHWVVSQPPDTYLKPLMTELLKRILDSNKRVQEAACS 510
Query: 1357 ALNDLLRGRPLDDIIDKLPEIWETL 1381
A L +++ L I +TL
Sbjct: 511 AF-ATLEEEACTELVPYLAYILDTL 534
Score = 35.8 bits (81), Expect = 0.44
Identities = 26/118 (22%), Positives = 52/118 (44%), Gaps = 5/118 (4%)
Query: 1697 LQELITITQKALQSQSWKMKAQGAIAMASIAKQTSSLVPPYLGMILTALLQGLAGRTWAG 1756
L ++ + ++ L W +K G + + +IA+ + PYL ++ L+Q L +
Sbjct: 403 LPHILPLLKELLFHHEWVVKESGILVLGAIAEGCMQGMIPYLPELIPHLIQCL-----SD 457
Query: 1757 KEELLKAIACVVTACSAELEKSVPNQPSTNEILQAVLKECSKENVKYKIVAISCAADI 1814
K+ L+++I C + A S P ++ +LK N + + A S A +
Sbjct: 458 KKALVRSITCWTLSRYAHWVVSQPPDTYLKPLMTELLKRILDSNKRVQEAACSAFATL 515
>gi|42821110 hypothetical protein LOC340602 [Homo sapiens]
Length = 503
Score = 40.8 bits (94), Expect = 0.014
Identities = 38/115 (33%), Positives = 52/115 (45%), Gaps = 8/115 (6%)
Query: 70 GASSRRLRARLYFSESTSLPLDRRGSPGPLGPAPHGLRRAA-PRGPARRTPRST----AL 124
G S RR + + P RR P PL P+ G R ++ P A + ++T AL
Sbjct: 143 GNSRRRKQPCRNQAAPAQKPPGRRLFPEPLPPSSPGFRPSSYPCSGASTSSQATQPGPAL 202
Query: 125 TSRRRAQRPRHGDRLRLRSEA-RPRAAGDWPCARGGAVRPGR--PHRPPRVESAR 176
S RP R+ L + A R RA+G P RG +PG PHR ++ AR
Sbjct: 203 LSHASEARPATRSRITLVASALRRRASGPGPVIRGCTAQPGPAFPHRATHLDPAR 257
>gi|24307963 zinc finger, DHHC-type containing 1 [Homo sapiens]
Length = 485
Score = 40.4 bits (93), Expect = 0.018
Identities = 43/126 (34%), Positives = 52/126 (41%), Gaps = 26/126 (20%)
Query: 48 GAGARPGLSQRRGREVRREAQGGASSRRLRARLYFSESTSLPLDRRGSPGPLGPAPHGLR 107
G A P L ++RGR + + RLR R+ RR GP AP R
Sbjct: 381 GPQAPPCLCRKRGRGACIKCE------RLRPRI-----------RRRGLGPPAAAP--AR 421
Query: 108 RAAPRGPARRTPRSTALTSRRRAQRPRHGDRLRLRSEARPRAAGDWPCARGGAVRP---G 164
R PR PA TP + + RR Q P + R R+ A P WP GA P G
Sbjct: 422 RRIPRTPALCTPLALPAPTTRRRQSPWTRFQWRRRAWAAPL----WPPRGAGADSPRWRG 477
Query: 165 RPHRPP 170
R RPP
Sbjct: 478 RRVRPP 483
>gi|239753673 PREDICTED: hypothetical protein [Homo sapiens]
Length = 380
Score = 38.9 bits (89), Expect = 0.052
Identities = 43/149 (28%), Positives = 54/149 (36%), Gaps = 7/149 (4%)
Query: 54 GLSQRRGREVRREAQGGASSRRLRARLYFSESTSLPLDRRGSPGP--LGPAPHGLRRAAP 111
G+ RGR A+GGA+ RL A ++ +R G L PAP +AA
Sbjct: 115 GIPGARGRLA--PARGGAARARLLA---VEVRVAVQSERHRHVGAVQLVPAPRQAAQAAD 169
Query: 112 RGPARRTPRSTALTSRRRAQRPRHGDRLRLRSEARPRAAGDWPCARGGAVRPGRPHRPPR 171
GP +P + R RPR PR P GG GR R P
Sbjct: 170 TGPRHASPGARRPAPGARRSRPRLLRPASPPPRPAPRRRSTAPRHEGGRPGRGRTRRQPH 229
Query: 172 VESARGAHAGRAATDQLERVFLRLGHAET 200
+ A A ER+ R G ET
Sbjct: 230 LAGAGCARLELEGARMGERLHRRQGAPET 258
>gi|209969838 transportin 2 (importin 3, karyopherin beta 2b) isoform
1 [Homo sapiens]
Length = 897
Score = 38.9 bits (89), Expect = 0.052
Identities = 42/144 (29%), Positives = 68/144 (47%), Gaps = 12/144 (8%)
Query: 1267 WNSRKGAAFGFNVIATRAGEQLAPFLPQLVPRLYRYQFDPNLGIRQAMTSIWNALVTD-- 1324
WN RK +A +V+A E+L LP L+P L F P ++++ + A+
Sbjct: 370 WNLRKCSAAALDVLANVFREEL---LPHLLPLLKGLLFHPEWVVKESGILVLGAIAEGCM 426
Query: 1325 KSMVDKYLKEILQDLVKNLTSNMWRVRESSCLALNDLLR---GRPLDDIIDKLPEIWETL 1381
+ MV YL E++ L++ L+ VR +C L+ +P D + P + E L
Sbjct: 427 QGMV-PYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPD--MHLKPLMTELL 483
Query: 1382 FRVQDDIKESVRKAAELALKTLSK 1405
R+ D K V++AA A TL +
Sbjct: 484 KRILDGNKR-VQEAACSAFATLEE 506
Score = 37.7 bits (86), Expect = 0.11
Identities = 29/120 (24%), Positives = 51/120 (42%), Gaps = 3/120 (2%)
Query: 1264 HAMWNSRKGAAFGFNVIATRAGEQLAPFLPQLVPRLYRYQFDPNLGIRQ--AMTSIWNAL 1321
H W ++ IA + + P+LP+L+P L + D +R T A
Sbjct: 405 HPEWVVKESGILVLGAIAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAH 464
Query: 1322 VTDKSMVDKYLKEILQDLVKNLTSNMWRVRESSCLALNDLLRGRPLDDIIDKLPEIWETL 1381
D +LK ++ +L+K + RV+E++C A L +++ L I +TL
Sbjct: 465 WVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAF-ATLEEEACTELVPYLSYILDTL 523
Score = 36.2 bits (82), Expect = 0.33
Identities = 28/118 (23%), Positives = 52/118 (44%), Gaps = 5/118 (4%)
Query: 1697 LQELITITQKALQSQSWKMKAQGAIAMASIAKQTSSLVPPYLGMILTALLQGLAGRTWAG 1756
L L+ + + L W +K G + + +IA+ + PYL ++ L+Q L +
Sbjct: 392 LPHLLPLLKGLLFHPEWVVKESGILVLGAIAEGCMQGMVPYLPELIPHLIQCL-----SD 446
Query: 1757 KEELLKAIACVVTACSAELEKSVPNQPSTNEILQAVLKECSKENVKYKIVAISCAADI 1814
K+ L+++IAC + A S P ++ +LK N + + A S A +
Sbjct: 447 KKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATL 504
>gi|209969836 transportin 2 (importin 3, karyopherin beta 2b) isoform
3 [Homo sapiens]
Length = 887
Score = 38.9 bits (89), Expect = 0.052
Identities = 42/144 (29%), Positives = 68/144 (47%), Gaps = 12/144 (8%)
Query: 1267 WNSRKGAAFGFNVIATRAGEQLAPFLPQLVPRLYRYQFDPNLGIRQAMTSIWNALVTD-- 1324
WN RK +A +V+A E+L LP L+P L F P ++++ + A+
Sbjct: 370 WNLRKCSAAALDVLANVFREEL---LPHLLPLLKGLLFHPEWVVKESGILVLGAIAEGCM 426
Query: 1325 KSMVDKYLKEILQDLVKNLTSNMWRVRESSCLALNDLLR---GRPLDDIIDKLPEIWETL 1381
+ MV YL E++ L++ L+ VR +C L+ +P D + P + E L
Sbjct: 427 QGMV-PYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPD--MHLKPLMTELL 483
Query: 1382 FRVQDDIKESVRKAAELALKTLSK 1405
R+ D K V++AA A TL +
Sbjct: 484 KRILDGNKR-VQEAACSAFATLEE 506
Score = 37.7 bits (86), Expect = 0.11
Identities = 29/120 (24%), Positives = 51/120 (42%), Gaps = 3/120 (2%)
Query: 1264 HAMWNSRKGAAFGFNVIATRAGEQLAPFLPQLVPRLYRYQFDPNLGIRQ--AMTSIWNAL 1321
H W ++ IA + + P+LP+L+P L + D +R T A
Sbjct: 405 HPEWVVKESGILVLGAIAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAH 464
Query: 1322 VTDKSMVDKYLKEILQDLVKNLTSNMWRVRESSCLALNDLLRGRPLDDIIDKLPEIWETL 1381
D +LK ++ +L+K + RV+E++C A L +++ L I +TL
Sbjct: 465 WVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAF-ATLEEEACTELVPYLSYILDTL 523
Score = 36.2 bits (82), Expect = 0.33
Identities = 28/118 (23%), Positives = 52/118 (44%), Gaps = 5/118 (4%)
Query: 1697 LQELITITQKALQSQSWKMKAQGAIAMASIAKQTSSLVPPYLGMILTALLQGLAGRTWAG 1756
L L+ + + L W +K G + + +IA+ + PYL ++ L+Q L +
Sbjct: 392 LPHLLPLLKGLLFHPEWVVKESGILVLGAIAEGCMQGMVPYLPELIPHLIQCL-----SD 446
Query: 1757 KEELLKAIACVVTACSAELEKSVPNQPSTNEILQAVLKECSKENVKYKIVAISCAADI 1814
K+ L+++IAC + A S P ++ +LK N + + A S A +
Sbjct: 447 KKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATL 504
>gi|48675813 transportin 2 (importin 3, karyopherin beta 2b) isoform 2
[Homo sapiens]
Length = 887
Score = 38.9 bits (89), Expect = 0.052
Identities = 42/144 (29%), Positives = 68/144 (47%), Gaps = 12/144 (8%)
Query: 1267 WNSRKGAAFGFNVIATRAGEQLAPFLPQLVPRLYRYQFDPNLGIRQAMTSIWNALVTD-- 1324
WN RK +A +V+A E+L LP L+P L F P ++++ + A+
Sbjct: 370 WNLRKCSAAALDVLANVFREEL---LPHLLPLLKGLLFHPEWVVKESGILVLGAIAEGCM 426
Query: 1325 KSMVDKYLKEILQDLVKNLTSNMWRVRESSCLALNDLLR---GRPLDDIIDKLPEIWETL 1381
+ MV YL E++ L++ L+ VR +C L+ +P D + P + E L
Sbjct: 427 QGMV-PYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPD--MHLKPLMTELL 483
Query: 1382 FRVQDDIKESVRKAAELALKTLSK 1405
R+ D K V++AA A TL +
Sbjct: 484 KRILDGNKR-VQEAACSAFATLEE 506
Score = 37.7 bits (86), Expect = 0.11
Identities = 29/120 (24%), Positives = 51/120 (42%), Gaps = 3/120 (2%)
Query: 1264 HAMWNSRKGAAFGFNVIATRAGEQLAPFLPQLVPRLYRYQFDPNLGIRQ--AMTSIWNAL 1321
H W ++ IA + + P+LP+L+P L + D +R T A
Sbjct: 405 HPEWVVKESGILVLGAIAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAH 464
Query: 1322 VTDKSMVDKYLKEILQDLVKNLTSNMWRVRESSCLALNDLLRGRPLDDIIDKLPEIWETL 1381
D +LK ++ +L+K + RV+E++C A L +++ L I +TL
Sbjct: 465 WVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAF-ATLEEEACTELVPYLSYILDTL 523
Score = 36.2 bits (82), Expect = 0.33
Identities = 28/118 (23%), Positives = 52/118 (44%), Gaps = 5/118 (4%)
Query: 1697 LQELITITQKALQSQSWKMKAQGAIAMASIAKQTSSLVPPYLGMILTALLQGLAGRTWAG 1756
L L+ + + L W +K G + + +IA+ + PYL ++ L+Q L +
Sbjct: 392 LPHLLPLLKGLLFHPEWVVKESGILVLGAIAEGCMQGMVPYLPELIPHLIQCL-----SD 446
Query: 1757 KEELLKAIACVVTACSAELEKSVPNQPSTNEILQAVLKECSKENVKYKIVAISCAADI 1814
K+ L+++IAC + A S P ++ +LK N + + A S A +
Sbjct: 447 KKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATL 504
>gi|62460637 importin 4 [Homo sapiens]
Length = 1081
Score = 38.9 bits (89), Expect = 0.052
Identities = 130/655 (19%), Positives = 237/655 (36%), Gaps = 127/655 (19%)
Query: 1312 QAMTSIWNALVTDKSMVDKYLKEILQ---DLVKNLT-SNMWRVRESSCLALNDLLRGRPL 1367
+A+ ++ L ++ ++ YL E+L ++ +N+ N R+R CL ++ + L
Sbjct: 223 EALEALDELLESEVPVITPYLSEVLTFCLEVARNVALGNAIRIRILCCLTFLVKVKSKAL 282
Query: 1368 DDIIDKL-PEIWETLFRV------------QDDIKESVRKAAELALKTLSKVCVKMCDPA 1414
+ ++L P + TLF + +D E EL +T V++ D
Sbjct: 283 --LKNRLLPPLLHTLFPIVAAEPPPGQLDPEDQDSEEEELEIELMGETPKHFAVQVVDML 340
Query: 1415 KGAAGQRTIAALLPCLLDKGMMSTVTEVRALSINTLVKISKSAGAMLKPHAPKLIPALLE 1474
+ L +L++ + S R + L +S AG ++ +L+P LL+
Sbjct: 341 ALHLPPEKLCPQLMPMLEEALRSESPYQRKAGLLVLAVLSDGAGDHIRQ---RLLPPLLQ 397
Query: 1475 SL--SVLEP-QVLNYLSLRATEQEKAAMDSARLSAAKSSPMMETINMCLQYLDVSVLG-- 1529
+ + +P QV+ +L A Q S L SS E + + L YL LG
Sbjct: 398 IVCKGLEDPSQVVRNAALFALGQF-----SENLQPHISSYSREVMPLLLAYLKSVPLGHT 452
Query: 1530 --------------------------ELVPRLCELIRSGVGLGTKGGCASVIVSLTTQCP 1563
EL+ + +L+R+ K S + ++ T
Sbjct: 453 HHLAKACYALENFVENLGPKVQPYLPELMECMLQLLRNPSSPRAKELAVSALGAIATAAQ 512
Query: 1564 QDLTPYSGKLMSAL----LSGLTDRNSVIQKSCAFAMGHLVRTSRDSS---TEKLLQKLN 1616
L PY +M L L+G D V +S +G L R + E+ Q
Sbjct: 513 ASLLPYFPAIMEHLREFLLTGREDLQPVQIQSLE-TLGVLARAVGEPMRPLAEECCQLGL 571
Query: 1617 GWYMEKEEPIYKTSCALTIHAIGRYSPDVLKNHAKEVLPLAFLGMHE------------- 1663
G + ++P + A+ + L H +++ L L +
Sbjct: 572 GLCDQVDDPDLRRCTYSLFAALSGLMGEGLAPHLEQITTLMLLSLRSTEGIVPQYDGSSS 631
Query: 1664 --IADEEKSEKEECNLWTEVWQENVPGSFGGIRLYLQELITITQKALQSQSWKMKAQGAI 1721
+ D+E +EE L E +E G ++++ + K
Sbjct: 632 FLLFDDESDGEEEEELMDEDVEEEDDSEISGY-------------SVENAFFDEKEDTCA 678
Query: 1722 AMASIAKQTSSLVPPYLGMILTALLQGLAG---RTWAGKEELLKAIACVV-TACSAELEK 1777
A+ I+ TS PY+ + + + L E L C + AC +
Sbjct: 679 AVGEISVNTSVAFLPYMESVFEEVFKLLECPHLNVRKAAHEALGQFCCALHKAC-----Q 733
Query: 1778 SVPNQPSTNEI-----------LQAVLKECSKENVKYKIVAI-----SCAADILKATKED 1821
S P++P+T + +QAV +E ++ V + A+ SC LK
Sbjct: 734 SCPSEPNTAALQAALARVVPSYMQAVNRERERQVVMAVLEALTGVLRSCGTLTLKPP--G 791
Query: 1822 RFQEFSNIVIPLIKKNSLESSGVRTTKNEEENEKEKELQLEYLLGAFESLGKAWP 1876
R E ++ ++++ + +EE E+E + Q EY E G+A P
Sbjct: 792 RLAELCGVLKAVLQRKTA------CQDTDEEEEEEDDDQAEYDAMLLEHAGEAIP 840
Score = 38.1 bits (87), Expect = 0.088
Identities = 103/545 (18%), Positives = 201/545 (36%), Gaps = 63/545 (11%)
Query: 1087 AARDAWQMTEEEYTPPAGAKVNDVVPWVLDVILNKHIISPNPHVRQAACIWLLSLVRKLS 1146
AA A E P + +V+P +L + K + + H AC L + V L
Sbjct: 413 AALFALGQFSENLQPHISSYSREVMPLLLAYL--KSVPLGHTHHLAKACYALENFVENLG 470
Query: 1147 THKEVKSHLKEIQSAFVSVL-SENDELSQDVASKGLGLVYELGNEQDQQ---ELVSTLVE 1202
+V+ +L E+ + +L + + ++++A LG + ++ L E
Sbjct: 471 P--KVQPYLPELMECMLQLLRNPSSPRAKELAVSALGAIATAAQASLLPYFPAIMEHLRE 528
Query: 1203 TLMTGKRVKHEVSGETVVFQGGALGKTPDGQGLSTYKELC-----SLASDLSQPDLVYKF 1257
L+TG+ V +++ G L + G+ + E C L + PDL
Sbjct: 529 FLLTGREDLQPVQIQSLETLG-VLARAV-GEPMRPLAEECCQLGLGLCDQVDDPDL---- 582
Query: 1258 MNLANHHAMWNSRKGAAFGFNVIATRAGEQLAPFLPQLVPRLYRYQFDPNLGIRQAMTSI 1317
R+ F ++ GE LAP L Q+ L GI
Sbjct: 583 ------------RRCTYSLFAALSGLMGEGLAPHLEQITT-LMLLSLRSTEGIVPQYDGS 629
Query: 1318 WNALVTDKSMVDKYLKEILQDLVK----------NLTSNMWRVRESSCLALNDLLRGRPL 1367
+ L+ D + +E++ + V+ ++ + + +E +C A+ ++ +
Sbjct: 630 SSFLLFDDESDGEEEEELMDEDVEEEDDSEISGYSVENAFFDEKEDTCAAVGEISVNTSV 689
Query: 1368 DDIIDKLPEIWETLFRVQDDIKESVRKAAELALK----TLSKVCVKMCDPAKGAAGQRTI 1423
+ + ++E +F++ + +VRKAA AL L K C AA Q +
Sbjct: 690 A-FLPYMESVFEEVFKLLECPHLNVRKAAHEALGQFCCALHKACQSCPSEPNTAALQAAL 748
Query: 1424 AALLPCLLDKGMMSTVTEVRALSINTLVKISKSAGAM-LKPHAPKLIPALLESLSVLEPQ 1482
A ++P + +V + L + +S G + LKP L E VL+
Sbjct: 749 ARVVPSYMQAVNRERERQVVMAVLEALTGVLRSCGTLTLKPPG-----RLAELCGVLKAV 803
Query: 1483 VLNYLSLRATEQEKAAMDSARLSAAKSSPMMETINMCLQYLDVSVLGE--------LVPR 1534
+ + + T++E+ D + A + ++E + L + G+ +P
Sbjct: 804 LQRKTACQDTDEEEEEEDDDQ--AEYDAMLLEHAGEAIPALAAAAGGDSFAPFFAGFLPL 861
Query: 1535 LCELIRSGVGLGTKGGCASVIVSLTTQCPQDLTPYSGKLMSALLSGLTDRNSVIQKSCAF 1594
L + G + K + + +L+ LLS + + ++ + F
Sbjct: 862 LVCKTKQGCTVAEKSFAVGTLAETIQGLGAASAQFVSRLLPVLLSTAQEADPEVRSNAIF 921
Query: 1595 AMGHL 1599
MG L
Sbjct: 922 GMGVL 926
>gi|239756987 PREDICTED: hypothetical protein XP_002345138 [Homo
sapiens]
Length = 459
Score = 38.5 bits (88), Expect = 0.067
Identities = 46/140 (32%), Positives = 56/140 (40%), Gaps = 28/140 (20%)
Query: 36 PPHQNWAVGGRCGAGARPG---LSQRRGREVRREAQGGASSRRLRARLYFSESTSLPLDR 92
PP + R A A PG S R+ R +GG +RR+ A ES + R
Sbjct: 110 PPAPQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAA---PESAAAAPGR 166
Query: 93 RGSPGPLGPAPHGLRRAAPRGPARRTPRSTALTSRRRAQRPRH------GDRLRLRSEAR 146
SP P P A R PR A S RRA +PRH G R S+A
Sbjct: 167 --SPSPADP--------GSTSSATRVPR--ARRSSRRALQPRHAAPDAPGAPSRSTSQAT 214
Query: 147 PRAAGDWPCARGGAVRPGRP 166
P A +P +R RPG P
Sbjct: 215 PPPAPRFPASR----RPGAP 230
>gi|239746003 PREDICTED: hypothetical protein XP_002344191 [Homo
sapiens]
Length = 459
Score = 38.5 bits (88), Expect = 0.067
Identities = 46/140 (32%), Positives = 56/140 (40%), Gaps = 28/140 (20%)
Query: 36 PPHQNWAVGGRCGAGARPG---LSQRRGREVRREAQGGASSRRLRARLYFSESTSLPLDR 92
PP + R A A PG S R+ R +GG +RR+ A ES + R
Sbjct: 110 PPAPQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAA---PESAAAAPGR 166
Query: 93 RGSPGPLGPAPHGLRRAAPRGPARRTPRSTALTSRRRAQRPRH------GDRLRLRSEAR 146
SP P P A R PR A S RRA +PRH G R S+A
Sbjct: 167 --SPSPADP--------GSTSSATRVPR--ARRSSRRALQPRHAAPDAPGAPSRSTSQAT 214
Query: 147 PRAAGDWPCARGGAVRPGRP 166
P A +P +R RPG P
Sbjct: 215 PPPAPRFPASR----RPGAP 230
>gi|239741585 PREDICTED: hypothetical protein XP_002342243 [Homo
sapiens]
Length = 439
Score = 38.5 bits (88), Expect = 0.067
Identities = 35/110 (31%), Positives = 41/110 (37%), Gaps = 27/110 (24%)
Query: 101 PAPHGLRRAAPRGPARRTPRSTALTSRRRAQRPRHGD-------------RLRLRSEARP 147
P+P L RAAP P R S SR R++ P RLR RP
Sbjct: 194 PSPTTLPRAAPLTPYRPGSPSPRGHSRLRSRPPTRAQLRVGANPLSPVPARLRGCHSVRP 253
Query: 148 RAAGDWPCARGGAVRPGRPHRPPR--------------VESARGAHAGRA 183
G C G P PH+PPR ++SAR A AG A
Sbjct: 254 EGGGVRSCRTLGCCPPTSPHQPPRLPVTPVPQSVALPSLQSARPAAAGAA 303
Score = 31.6 bits (70), Expect = 8.2
Identities = 14/35 (40%), Positives = 19/35 (54%)
Query: 971 GSFLDSTSPLLAIAACTALGEIGRNGPLPIPSEGS 1005
G LD+ P L A CT LG+ G + P P+ G+
Sbjct: 11 GGVLDADCPCLFYALCTRLGDSGPSSPPPVRPSGN 45
Score = 31.6 bits (70), Expect = 8.2
Identities = 25/72 (34%), Positives = 30/72 (41%), Gaps = 4/72 (5%)
Query: 99 LGPAPHGLRRAAPRGPARRTPRSTALTSRRRAQRPRHGDRLRLRSEARPRAAGDWPCARG 158
LG P PR P P+S AL S + A+ G RL P+AA +
Sbjct: 264 LGCCPPTSPHQPPRLPVTPVPQSVALPSLQSARPAAAGAAPRL----SPQAARCTALSTE 319
Query: 159 GAVRPGRPHRPP 170
RPG P RPP
Sbjct: 320 KPDRPGPPRRPP 331
>gi|239754468 PREDICTED: hypothetical protein [Homo sapiens]
Length = 146
Score = 38.1 bits (87), Expect = 0.088
Identities = 40/113 (35%), Positives = 47/113 (41%), Gaps = 18/113 (15%)
Query: 53 PGLSQRRGREVRREAQGGASSRRLRARLYFSESTSLPLDRRGSPGPLGPAPHGLRRAAPR 112
PG + GR +RR +G SSRRL S P R G+P P GP P R
Sbjct: 24 PGHQRASGRHLRRR-RGSCSSRRL----------SGPGRRAGAPTPRGPPPRP-RSFPET 71
Query: 113 GPARRTPRSTALTSRRRAQRPRHGDRLRLRSEARPRAAGD--WPCARGGAVRP 163
GPAR A RA RP G+R L ++ R G W R A P
Sbjct: 72 GPAR---LGAAAGPSSRA-RPSRGERPWLAAQLRGLQVGQCCWGHRRRSAPEP 120
>gi|239749023 PREDICTED: hypothetical protein XP_002346884 [Homo
sapiens]
Length = 159
Score = 38.1 bits (87), Expect = 0.088
Identities = 40/113 (35%), Positives = 47/113 (41%), Gaps = 18/113 (15%)
Query: 53 PGLSQRRGREVRREAQGGASSRRLRARLYFSESTSLPLDRRGSPGPLGPAPHGLRRAAPR 112
PG + GR +RR +G SSRRL S P R G+P P GP P R
Sbjct: 37 PGHQRASGRHLRRR-RGSCSSRRL----------SGPGRRAGAPTPRGPPPRP-RSFPET 84
Query: 113 GPARRTPRSTALTSRRRAQRPRHGDRLRLRSEARPRAAGD--WPCARGGAVRP 163
GPAR A RA RP G+R L ++ R G W R A P
Sbjct: 85 GPAR---LGAAAGPSSRA-RPSRGERPWLAAQLRGLQVGQCCWGHRRRSAPEP 133
>gi|239746609 PREDICTED: hypothetical protein XP_002343799 [Homo
sapiens]
Length = 245
Score = 38.1 bits (87), Expect = 0.088
Identities = 47/148 (31%), Positives = 61/148 (41%), Gaps = 17/148 (11%)
Query: 58 RRGREVRREAQGGASSRRLRARLYFS---ESTSLPLDRRGSPGPLGPAPH-----GLRRA 109
RR R + R + A R R R + +T +P R PGP G H G++R
Sbjct: 97 RRRRTLGRRCRPPAPRPRPRPRRKLALDQAATRIPAARPRPPGPGGRGSHWKIQPGVQRL 156
Query: 110 APRGPARRTPRSTALTSRRRAQRPR------HGDRLRLRSEAR-PRAAGDWPCARGGAVR 162
PR PR RRRA RP G R +++R R G + +R R
Sbjct: 157 -PRPTPSAQPRPGP-PERRRASRPLIGCGRGGGGTWRRAADSRWRRPGGGFQRSRREKAR 214
Query: 163 PGRPHRPPRVESARGAHAGRAATDQLER 190
P R P RV S +GA AG A + R
Sbjct: 215 PPRRLPPDRVLSWQGAVAGTGAALRTSR 242
>gi|239743042 PREDICTED: hypothetical protein XP_002342725 [Homo
sapiens]
Length = 159
Score = 38.1 bits (87), Expect = 0.088
Identities = 40/113 (35%), Positives = 47/113 (41%), Gaps = 18/113 (15%)
Query: 53 PGLSQRRGREVRREAQGGASSRRLRARLYFSESTSLPLDRRGSPGPLGPAPHGLRRAAPR 112
PG + GR +RR +G SSRRL S P R G+P P GP P R
Sbjct: 37 PGHQRASGRHLRRR-RGSCSSRRL----------SGPGRRAGAPTPRGPPPRP-RSFPET 84
Query: 113 GPARRTPRSTALTSRRRAQRPRHGDRLRLRSEARPRAAGD--WPCARGGAVRP 163
GPAR A RA RP G+R L ++ R G W R A P
Sbjct: 85 GPAR---LGAAAGPSSRA-RPSRGERPWLAAQLRGLQVGQCCWGHRRRSAPEP 133
>gi|239754081 PREDICTED: hypothetical protein XP_002345876 [Homo
sapiens]
Length = 355
Score = 37.7 bits (86), Expect = 0.11
Identities = 41/131 (31%), Positives = 52/131 (39%), Gaps = 22/131 (16%)
Query: 56 SQRRGREVRREAQGGASSRRLRARLYFSESTSLPLDRRGSPGPLGPAPHGLRRAAPRGPA 115
+ R G + + +SSR R RL P RRG+ LGP P RAA +G
Sbjct: 130 NSRAGGGLTKYNSAHSSSRVPRPRL--------PSQRRGASCGLGPGPES--RAARQGLG 179
Query: 116 RRTPRSTALTSRRRAQRPRHGDRLRLRSEARP--------RAAGDWPCARGGAVRPGRPH 167
R+ R+ R +RP G +A P RAAG ARG P R
Sbjct: 180 GRSARARTRRGPHRTRRPEPGPHHTGARQAGPLPGTRGRTRAAGTGSAARG----PARHL 235
Query: 168 RPPRVESARGA 178
R V +A A
Sbjct: 236 RGGSVAAAAAA 246
>gi|239751123 PREDICTED: hypothetical protein XP_002347725 [Homo
sapiens]
Length = 296
Score = 37.7 bits (86), Expect = 0.11
Identities = 29/81 (35%), Positives = 33/81 (40%), Gaps = 2/81 (2%)
Query: 104 HGLRRAAPRGPARRTPRSTALTSRRRAQRPRHGDRLRLRSEARPRAAGDWPC-ARGGAVR 162
HG AAP P L S R AQRPR G R R + P + C A A R
Sbjct: 187 HGHLAAAPGAWRAAAPAGWGLGSARAAQRPREGSR-RFPAPPAPERSRTPDCPAAPAAPR 245
Query: 163 PGRPHRPPRVESARGAHAGRA 183
RP RPP +G G +
Sbjct: 246 MRRPRRPPHRLRGQGRVKGNS 266
>gi|239748667 PREDICTED: hypothetical protein XP_002346761 [Homo
sapiens]
Length = 355
Score = 37.7 bits (86), Expect = 0.11
Identities = 41/131 (31%), Positives = 52/131 (39%), Gaps = 22/131 (16%)
Query: 56 SQRRGREVRREAQGGASSRRLRARLYFSESTSLPLDRRGSPGPLGPAPHGLRRAAPRGPA 115
+ R G + + +SSR R RL P RRG+ LGP P RAA +G
Sbjct: 130 NSRAGGGLTKYNSAHSSSRVPRPRL--------PSQRRGASCGLGPGPES--RAARQGLG 179
Query: 116 RRTPRSTALTSRRRAQRPRHGDRLRLRSEARP--------RAAGDWPCARGGAVRPGRPH 167
R+ R+ R +RP G +A P RAAG ARG P R
Sbjct: 180 GRSARARTRRGPHRTRRPEPGPHHTGARQAGPLPGTRGRTRAAGTGSAARG----PARHL 235
Query: 168 RPPRVESARGA 178
R V +A A
Sbjct: 236 RGGSVAAAAAA 246
>gi|239742692 PREDICTED: hypothetical protein XP_002342583 [Homo
sapiens]
Length = 355
Score = 37.7 bits (86), Expect = 0.11
Identities = 41/131 (31%), Positives = 52/131 (39%), Gaps = 22/131 (16%)
Query: 56 SQRRGREVRREAQGGASSRRLRARLYFSESTSLPLDRRGSPGPLGPAPHGLRRAAPRGPA 115
+ R G + + +SSR R RL P RRG+ LGP P RAA +G
Sbjct: 130 NSRAGGGLTKYNSAHSSSRVPRPRL--------PSQRRGASCGLGPGPES--RAARQGLG 179
Query: 116 RRTPRSTALTSRRRAQRPRHGDRLRLRSEARP--------RAAGDWPCARGGAVRPGRPH 167
R+ R+ R +RP G +A P RAAG ARG P R
Sbjct: 180 GRSARARTRRGPHRTRRPEPGPHHTGARQAGPLPGTRGRTRAAGTGSAARG----PARHL 235
Query: 168 RPPRVESARGA 178
R V +A A
Sbjct: 236 RGGSVAAAAAA 246
>gi|238624195 hypothetical protein LOC221545 isoform 3 [Homo
sapiens]
Length = 496
Score = 37.4 bits (85), Expect = 0.15
Identities = 54/176 (30%), Positives = 62/176 (35%), Gaps = 50/176 (28%)
Query: 44 GGRCGAGARPGLSQRRGRE----------------------VRREAQGGASSRRLRA-RL 80
GGR G G RP RG E V R GA RR RA R
Sbjct: 31 GGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRA 90
Query: 81 YFSESTSLPLDRRG---SPGPLGPAPHGLRRAAPRG---------------PARRTPRST 122
S L RRG + G + AP R PRG P+R +P T
Sbjct: 91 RTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT 150
Query: 123 ALTSRRRAQRPRHGDRLRLRSEARPRAAGDWPCARGGAVRPG--RPHRPPRVESAR 176
R A RP+ RL L R G C R G +RPG H P R ++R
Sbjct: 151 -----RPAGRPQQPARLALGE--RSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASR 199
>gi|239753399 PREDICTED: hypothetical protein [Homo sapiens]
Length = 165
Score = 37.0 bits (84), Expect = 0.20
Identities = 48/159 (30%), Positives = 55/159 (34%), Gaps = 43/159 (27%)
Query: 22 SYRKEHRPFWEHQPPPHQNWAVGGRCGAGARPGLSQRRGREVRREAQGGASSRRLRARLY 81
S RK H P PPP G CG G RGRE R GG + A
Sbjct: 21 SNRKCHSP-----PPPPSGTLTGAECGGG--------RGRERR----GGGTRHTHHAENC 63
Query: 82 FSESTSLPLDRRGSPGPLGPAPHGLRRAAPRGPARRTPRSTALTSRRRAQRPRHGDRLRL 141
F+ + G AAPR P RT R A + ++ R
Sbjct: 64 FTAFLKVA--------------EGAAAAAPRKP--RTGRGGAAATAAVTRKERE------ 101
Query: 142 RSEARPRAAGDWPCARGGAVRPGRPHRPPRVESARGAHA 180
+ AR R GD GGA G R PR A AHA
Sbjct: 102 TAPARDRGGGD----GGGARADGLRGRSPRRRPAGRAHA 136
>gi|239741865 PREDICTED: hypothetical protein XP_002342328 [Homo
sapiens]
Length = 165
Score = 37.0 bits (84), Expect = 0.20
Identities = 48/159 (30%), Positives = 55/159 (34%), Gaps = 43/159 (27%)
Query: 22 SYRKEHRPFWEHQPPPHQNWAVGGRCGAGARPGLSQRRGREVRREAQGGASSRRLRARLY 81
S RK H P PPP G CG G RGRE R GG + A
Sbjct: 21 SNRKCHSP-----PPPPSGTLTGAECGGG--------RGRERR----GGGTRHTHHAENC 63
Query: 82 FSESTSLPLDRRGSPGPLGPAPHGLRRAAPRGPARRTPRSTALTSRRRAQRPRHGDRLRL 141
F+ + G AAPR P RT R A + ++ R
Sbjct: 64 FTAFLKVA--------------EGAAAAAPRKP--RTGRGGAAATAAVTRKERE------ 101
Query: 142 RSEARPRAAGDWPCARGGAVRPGRPHRPPRVESARGAHA 180
+ AR R GD GGA G R PR A AHA
Sbjct: 102 TAPARDRGGGD----GGGARADGLRGRSPRRRPAGRAHA 136
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 74,864,258
Number of Sequences: 37866
Number of extensions: 3418945
Number of successful extensions: 14689
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 176
Number of HSP's that attempted gapping in prelim test: 14318
Number of HSP's gapped (non-prelim): 521
length of query: 2017
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1900
effective length of database: 13,817,196
effective search space: 26252672400
effective search space used: 26252672400
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.