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Search of human proteins with 28872812
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|28872812 MORC family CW-type zinc finger 3 [Homo sapiens]
(939 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|28872812 MORC family CW-type zinc finger 3 [Homo sapiens] 1885 0.0
gi|145553976 zinc finger, CW type with coiled-coil domain 2 isof... 527 e-149
gi|145553971 zinc finger, CW type with coiled-coil domain 2 isof... 526 e-149
gi|221625538 MORC family CW-type zinc finger 1 [Homo sapiens] 199 1e-50
gi|7662340 MORC family CW-type zinc finger 2 [Homo sapiens] 121 3e-27
gi|71061468 centromere protein E [Homo sapiens] 65 4e-10
gi|7705415 hook homolog 1 [Homo sapiens] 58 5e-08
gi|118498356 kinectin 1 isoform a [Homo sapiens] 54 5e-07
gi|118498368 kinectin 1 isoform c [Homo sapiens] 54 5e-07
gi|33620775 kinectin 1 isoform a [Homo sapiens] 54 5e-07
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 54 7e-07
gi|112420968 coiled-coil domain containing 158 [Homo sapiens] 54 7e-07
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 54 7e-07
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 53 1e-06
gi|16262452 cingulin [Homo sapiens] 53 2e-06
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 53 2e-06
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 52 3e-06
gi|115648142 centrosomal protein 164kDa [Homo sapiens] 52 3e-06
gi|56550043 sarcolemma associated protein [Homo sapiens] 52 3e-06
gi|4502443 dystonin isoform 1e precursor [Homo sapiens] 51 4e-06
gi|34577114 cytomatrix protein p110 [Homo sapiens] 51 6e-06
gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens] 50 8e-06
gi|117553613 coiled-coil domain containing 151 [Homo sapiens] 50 8e-06
gi|95089461 discs large homolog 5 [Homo sapiens] 50 1e-05
gi|41872583 Rho-associated, coiled-coil containing protein kinas... 50 1e-05
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 50 1e-05
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 50 1e-05
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 49 2e-05
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 49 2e-05
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 49 2e-05
>gi|28872812 MORC family CW-type zinc finger 3 [Homo sapiens]
Length = 939
Score = 1885 bits (4883), Expect = 0.0
Identities = 939/939 (100%), Positives = 939/939 (100%)
Query: 1 MAAQPPRGIRLSALCPKFLHTNSTSHTWPFSAVAELIDNAYDPDVNAKQIWIDKTVINDH 60
MAAQPPRGIRLSALCPKFLHTNSTSHTWPFSAVAELIDNAYDPDVNAKQIWIDKTVINDH
Sbjct: 1 MAAQPPRGIRLSALCPKFLHTNSTSHTWPFSAVAELIDNAYDPDVNAKQIWIDKTVINDH 60
Query: 61 ICLTFTDNGNGMTSDKLHKMLSFGFSDKVTMNGHVPVGLYGNGFKSGSMRLGKDAIVFTK 120
ICLTFTDNGNGMTSDKLHKMLSFGFSDKVTMNGHVPVGLYGNGFKSGSMRLGKDAIVFTK
Sbjct: 61 ICLTFTDNGNGMTSDKLHKMLSFGFSDKVTMNGHVPVGLYGNGFKSGSMRLGKDAIVFTK 120
Query: 121 NGESMSVGLLSQTYLEVIKAEHVVVPIVAFNKHRQMINLAESKASLAAILEHSLFSTEQK 180
NGESMSVGLLSQTYLEVIKAEHVVVPIVAFNKHRQMINLAESKASLAAILEHSLFSTEQK
Sbjct: 121 NGESMSVGLLSQTYLEVIKAEHVVVPIVAFNKHRQMINLAESKASLAAILEHSLFSTEQK 180
Query: 181 LLAELDAIIGKKGTRIIIWNLRSYKNATEFDFEKDKYDIRIPEDLDEITGKKGYKKQERM 240
LLAELDAIIGKKGTRIIIWNLRSYKNATEFDFEKDKYDIRIPEDLDEITGKKGYKKQERM
Sbjct: 181 LLAELDAIIGKKGTRIIIWNLRSYKNATEFDFEKDKYDIRIPEDLDEITGKKGYKKQERM 240
Query: 241 DQIAPESDYSLRAYCSILYLKPRMQIILRGQKVKTQLVSKSLAYIERDVYRPKFLSKTVR 300
DQIAPESDYSLRAYCSILYLKPRMQIILRGQKVKTQLVSKSLAYIERDVYRPKFLSKTVR
Sbjct: 241 DQIAPESDYSLRAYCSILYLKPRMQIILRGQKVKTQLVSKSLAYIERDVYRPKFLSKTVR 300
Query: 301 ITFGFNCRNKDHYGIMMYHRNRLIKAYEKVGCQLRANNMGVGVVGIIECNFLKPTHNKQD 360
ITFGFNCRNKDHYGIMMYHRNRLIKAYEKVGCQLRANNMGVGVVGIIECNFLKPTHNKQD
Sbjct: 301 ITFGFNCRNKDHYGIMMYHRNRLIKAYEKVGCQLRANNMGVGVVGIIECNFLKPTHNKQD 360
Query: 361 FDYTNEYRLTITALGEKLNDYWNEMKVKKNTEYPLNLPVEDIQKRPDQTWVQCDACLKWR 420
FDYTNEYRLTITALGEKLNDYWNEMKVKKNTEYPLNLPVEDIQKRPDQTWVQCDACLKWR
Sbjct: 361 FDYTNEYRLTITALGEKLNDYWNEMKVKKNTEYPLNLPVEDIQKRPDQTWVQCDACLKWR 420
Query: 421 KLPDGMDQLPEKWYCSNNPDPQFRNCEVPEEPEDEDLVHPTYEKTYKKTNKEKFRIRQPE 480
KLPDGMDQLPEKWYCSNNPDPQFRNCEVPEEPEDEDLVHPTYEKTYKKTNKEKFRIRQPE
Sbjct: 421 KLPDGMDQLPEKWYCSNNPDPQFRNCEVPEEPEDEDLVHPTYEKTYKKTNKEKFRIRQPE 480
Query: 481 MIPRINAELLFRPTALSTPSFSSPKESVPRRHLSEGTNSYATRLLNNHQVPPQSEPESNS 540
MIPRINAELLFRPTALSTPSFSSPKESVPRRHLSEGTNSYATRLLNNHQVPPQSEPESNS
Sbjct: 481 MIPRINAELLFRPTALSTPSFSSPKESVPRRHLSEGTNSYATRLLNNHQVPPQSEPESNS 540
Query: 541 LKRRLSTRSSILNAKNRRLSSQFENSVYKGDDDDEDVIILEENSTPKPAVDHDIDMKSEQ 600
LKRRLSTRSSILNAKNRRLSSQFENSVYKGDDDDEDVIILEENSTPKPAVDHDIDMKSEQ
Sbjct: 541 LKRRLSTRSSILNAKNRRLSSQFENSVYKGDDDDEDVIILEENSTPKPAVDHDIDMKSEQ 600
Query: 601 SHVEQGGVQVEFVGDSEPCGQTGSTSTSSSRCDQGNTAATQTEVPSLVVKKEETVEDEID 660
SHVEQGGVQVEFVGDSEPCGQTGSTSTSSSRCDQGNTAATQTEVPSLVVKKEETVEDEID
Sbjct: 601 SHVEQGGVQVEFVGDSEPCGQTGSTSTSSSRCDQGNTAATQTEVPSLVVKKEETVEDEID 660
Query: 661 VRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQELRNQLLLVTEEKENYKRQCHMF 720
VRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQELRNQLLLVTEEKENYKRQCHMF
Sbjct: 661 VRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQELRNQLLLVTEEKENYKRQCHMF 720
Query: 721 TDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFLLESINGKSESPDHMVSQYQQALEEI 780
TDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFLLESINGKSESPDHMVSQYQQALEEI
Sbjct: 721 TDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFLLESINGKSESPDHMVSQYQQALEEI 780
Query: 781 ERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEVELL 840
ERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEVELL
Sbjct: 781 ERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEVELL 840
Query: 841 EMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEESVNHMDGESLKLRSLRVNVG 900
EMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEESVNHMDGESLKLRSLRVNVG
Sbjct: 841 EMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEESVNHMDGESLKLRSLRVNVG 900
Query: 901 QLLAMIVPDLDLQQVNYDVDVVDEILGQVVEQMSEISST 939
QLLAMIVPDLDLQQVNYDVDVVDEILGQVVEQMSEISST
Sbjct: 901 QLLAMIVPDLDLQQVNYDVDVVDEILGQVVEQMSEISST 939
>gi|145553976 zinc finger, CW type with coiled-coil domain 2 isoform
a [Homo sapiens]
Length = 937
Score = 527 bits (1357), Expect = e-149
Identities = 338/893 (37%), Positives = 482/893 (53%), Gaps = 105/893 (11%)
Query: 8 GIRLSALCPKFLHTNSTSHTWPFSAVAELIDNAYDPDVNAKQIWIDKTVINDHICLTFTD 67
GIRLS + P++L +NS+SHT PFSA+AEL+DNA DPDV+A+ ++ID + + CLTFTD
Sbjct: 29 GIRLSTMSPRYLQSNSSSHTRPFSAIAELLDNAVDPDVSARTVFIDVEEVKNKSCLTFTD 88
Query: 68 NGNGMTSDKLHKMLSFGFSDKVTMNGHVPVGLYGNGFKSGSMRLGKDAIVFTKNGESMSV 127
+G GMT KLH+MLSFGF+DKV P+G++GNGFKSGSMRLGKDA+VFTKNG +++V
Sbjct: 89 DGCGMTPHKLHRMLSFGFTDKVIKKSQCPIGVFGNGFKSGSMRLGKDALVFTKNGGTLTV 148
Query: 128 GLLSQTYLEVIKAEHVVVPIVAFN-KHRQMINLAESKASLAAILEHSLFSTEQKLLAELD 186
GLLSQTYLE ++A+ V+VPIV FN ++++MI +S SL AIL +S+F+ E LLA+ D
Sbjct: 149 GLLSQTYLECVQAQAVIVPIVPFNQQNKKMIITEDSLPSLEAILNYSIFNRENDLLAQFD 208
Query: 187 AIIGKKGTRIIIWNLRSYKNA-TEFDFEKDKYDIRIPEDLDEITGKKGYKKQERMDQIAP 245
AI GKKGTR++IWN+R KN +E DF+ D+YDI + D D G E P
Sbjct: 209 AIPGKKGTRVLIWNIRRNKNGKSELDFDTDQYDILV-SDFDTEEKMTGGVTSE-----LP 262
Query: 246 ESDYSLRAYCSILYLKPRMQIILRGQKVKTQLVSKSLAYIERDVYRPKFLSKTVRITFGF 305
E++YSLRA+C ILY+KPRM+I LR +KV TQ+++KSLA +E D Y+P F +K VRITFGF
Sbjct: 263 ETEYSLRAFCGILYMKPRMKIFLRQKKVTTQMIAKSLANVEYDTYKPTFTNKQVRITFGF 322
Query: 306 NCRNKDHYGIMMYHRNRLIKAYEKVGCQLR-ANNMGVGVVGIIECNFLKPTHNKQDFDYT 364
+C+N + +GIMMYH NRLIK++EKVGCQ++ GVGV+G+IECNFLKP +NKQDF+YT
Sbjct: 323 SCKNSNQFGIMMYHNNRLIKSFEKVGCQVKPTRGEGVGVIGVIECNFLKPAYNKQDFEYT 382
Query: 365 NEYRLTITALGEKLNDYWNEMKVKKNTEYPLNLPVEDIQKRPDQTWVQCDACLKWRKLPD 424
EYRLTI AL +KLN YW E + N E + I K PDQTWVQCD CLKWRKLP
Sbjct: 383 KEYRLTINALAQKLNAYWKEKTSQDNFE--TSTVARPIPKVPDQTWVQCDECLKWRKLPG 440
Query: 425 GMD--QLPEKWYCSNNPDPQFRNCEVPEEPE--DEDLVHPTYEKTYKKTNKEKFRIRQPE 480
+D LP +W+C N P++R C VPEE E DEDL K K++ + + +
Sbjct: 441 KIDPSMLPARWFCYYNSHPKYRRCSVPEEQELTDEDL-------CLSKAKKQEQTVEEKK 493
Query: 481 MIPRINAELLFRPTALSTPSFSSPKESVPRRHLSEGTN-SYATRLLNNHQVPPQSEPESN 539
+P N + FS+P + + + ++ N + +++ V P ES
Sbjct: 494 KMPMENE---------NHQVFSNPPKILTVQEMAGLNNKTIGYEGIHSPSVLPSGGEESR 544
Query: 540 SLKRRLS-TRSSILN--------------AKNRRLSSQFENS-----------------V 567
S +L SS+L K RRL ++
Sbjct: 545 SPSLQLKPLDSSVLQFSSKYKWILGEEPVEKRRRLQNEMTTPSLDYSMPAPYRRVEAPVA 604
Query: 568 YKGDDDDEDVIILEENSTP-----KPAVDHDIDMKSEQSHV-------EQGGVQVEFVGD 615
Y ++ D E ++ P P + E S + QG + E + D
Sbjct: 605 YPEGENSHDKSSSERSTPPYLFPEYPEASKNTGQNREVSILYPGAKDQRQGSLLPEELED 664
Query: 616 SEPC-----GQTGSTSTSSSRCDQGNTAA----------TQTEVPSLVVKKEETVEDEID 660
P GST+ + ++G A + + + +EE E
Sbjct: 665 QMPRLVAEESNRGSTTINKEEVNKGPFVAVVGVAKGVRDSGAPIQLIPFNREELAERRKA 724
Query: 661 VRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQELRNQ-----LLLVTEEKENYKR 715
V + + S A E + G +L+NQ L TE+ E
Sbjct: 725 VESWNPVPYSVASAAIPAAAIGEKARGYEESEGHNTPKLKNQRELEELKRTTEKLERVLA 784
Query: 716 QCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFLLESINGKSESPDHM---VSQ 772
+ ++F +++ L+Q ++ K+ H+ ++ + G S HM ++
Sbjct: 785 ERNLFQQKVEELEQERNHWQSEF--KKVQHEL----VIYSTQEAEGLYWSKKHMGYRQAE 838
Query: 773 YQQALEEIERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQLDDVFRQLDK 825
+Q E+ER K++ L+ E K+++ + DD+ R L K
Sbjct: 839 FQILKAELERTKEEKQELKEKLKETETHLEMLQKAQVSYRTPEGDDLERALAK 891
Score = 59.7 bits (143), Expect = 1e-08
Identities = 51/196 (26%), Positives = 88/196 (44%), Gaps = 12/196 (6%)
Query: 747 STETDAVFLLESINGKSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECS--QCSNNE 804
S A + E G ES H + + E+E LK+ L+ V AE + Q E
Sbjct: 737 SAAIPAAAIGEKARGYEESEGHNTPKLKNQ-RELEELKRTTEKLERVLAERNLFQQKVEE 795
Query: 805 SKSEMDEMAVQLDDVFRQLDKCSIERDQ----YKSEVELLEMEKSQIRSQCEELKTEVEQ 860
+ E + + V +L S + + K + + E ++++ E K E ++
Sbjct: 796 LEQERNHWQSEFKKVQHELVIYSTQEAEGLYWSKKHMGYRQAEFQILKAELERTKEEKQE 855
Query: 861 LKSTNQQTATDVSTSSNIEESVNHMDGESL-----KLRSLRVNVGQLLAMIVPDLDLQQV 915
LK ++T T + + S +G+ L KL LR++V LL ++P L+L+++
Sbjct: 856 LKEKLKETETHLEMLQKAQVSYRTPEGDDLERALAKLTRLRIHVSYLLTSVLPHLELREI 915
Query: 916 NYDVDVVDEILGQVVE 931
YD + VD IL V+E
Sbjct: 916 GYDSEQVDGILYTVLE 931
>gi|145553971 zinc finger, CW type with coiled-coil domain 2 isoform
b [Homo sapiens]
Length = 900
Score = 526 bits (1355), Expect = e-149
Identities = 267/486 (54%), Positives = 348/486 (71%), Gaps = 22/486 (4%)
Query: 8 GIRLSALCPKFLHTNSTSHTWPFSAVAELIDNAYDPDVNAKQIWIDKTVINDHICLTFTD 67
GIRLS + P++L +NS+SHT PFSA+AEL+DNA DPDV+A+ ++ID + + CLTFTD
Sbjct: 29 GIRLSTMSPRYLQSNSSSHTRPFSAIAELLDNAVDPDVSARTVFIDVEEVKNKSCLTFTD 88
Query: 68 NGNGMTSDKLHKMLSFGFSDKVTMNGHVPVGLYGNGFKSGSMRLGKDAIVFTKNGESMSV 127
+G GMT KLH+MLSFGF+DKV P+G++GNGFKSGSMRLGKDA+VFTKNG +++V
Sbjct: 89 DGCGMTPHKLHRMLSFGFTDKVIKKSQCPIGVFGNGFKSGSMRLGKDALVFTKNGGTLTV 148
Query: 128 GLLSQTYLEVIKAEHVVVPIVAFN-KHRQMINLAESKASLAAILEHSLFSTEQKLLAELD 186
GLLSQTYLE ++A+ V+VPIV FN ++++MI +S SL AIL +S+F+ E LLA+ D
Sbjct: 149 GLLSQTYLECVQAQAVIVPIVPFNQQNKKMIITEDSLPSLEAILNYSIFNRENDLLAQFD 208
Query: 187 AIIGKKGTRIIIWNLRSYKNA-TEFDFEKDKYDIRIPEDLDEITGKKGYKKQERMDQIAP 245
AI GKKGTR++IWN+R KN +E DF+ D+YDI + D D G E P
Sbjct: 209 AIPGKKGTRVLIWNIRRNKNGKSELDFDTDQYDILV-SDFDTEEKMTGGVTSE-----LP 262
Query: 246 ESDYSLRAYCSILYLKPRMQIILRGQKVKTQLVSKSLAYIERDVYRPKFLSKTVRITFGF 305
E++YSLRA+C ILY+KPRM+I LR +KV TQ+++KSLA +E D Y+P F +K VRITFGF
Sbjct: 263 ETEYSLRAFCGILYMKPRMKIFLRQKKVTTQMIAKSLANVEYDTYKPTFTNKQVRITFGF 322
Query: 306 NCRNKDHYGIMMYHRNRLIKAYEKVGCQLR-ANNMGVGVVGIIECNFLKPTHNKQDFDYT 364
+C+N + +GIMMYH NRLIK++EKVGCQ++ GVGV+G+IECNFLKP +NKQDF+YT
Sbjct: 323 SCKNSNQFGIMMYHNNRLIKSFEKVGCQVKPTRGEGVGVIGVIECNFLKPAYNKQDFEYT 382
Query: 365 NEYRLTITALGEKLNDYWNEMKVKKNTEYPLNLPVEDIQKRPDQTWVQCDACLKWRKLPD 424
EYRLTI AL +KLN YW E + N E + I K PDQTWVQCD CLKWRKLP
Sbjct: 383 KEYRLTINALAQKLNAYWKEKTSQDNFE--TSTVARPIPKVPDQTWVQCDECLKWRKLPG 440
Query: 425 GMD--QLPEKWYCSNNPDPQFRNCEVPEEPE--DEDLVHPTYEKTYKKTNKEKFRIRQPE 480
+D LP +W+C N P++R C VPEE E DEDL K K++ + + +
Sbjct: 441 KIDPSMLPARWFCYYNSHPKYRRCSVPEEQELTDEDL-------CLSKAKKQEQTVEEKK 493
Query: 481 MIPRIN 486
+P N
Sbjct: 494 KMPMEN 499
>gi|221625538 MORC family CW-type zinc finger 1 [Homo sapiens]
Length = 984
Score = 199 bits (505), Expect = 1e-50
Identities = 177/683 (25%), Positives = 288/683 (42%), Gaps = 140/683 (20%)
Query: 18 FLHTNSTSHTWPFSAVAELIDNAYDPDVNAKQIW-IDKTVINDHICLTFTDNGNGMTSDK 76
F+H NST+H++ F A+AEL+DNA D ++ +D + L F D+G GM+ ++
Sbjct: 17 FIHANSTTHSFLFGALAELLDNARDAGAERLDVFSVDNEKLQGGFMLCFLDDGCGMSPEE 76
Query: 77 LHKMLSFGFSDKVTMNGHVPVGLYGNGFKSGSMRLGKDAIVFTKNGESMSVGLLSQTYLE 136
++ FG S K ++ +G YGNG KSGSMR+GKD I+FTK E+M+ SQT+ E
Sbjct: 77 ASDIIYFGRSKK-RLSTLKFIGQYGNGLKSGSMRIGKDFILFTKKEETMTCVFFSQTFCE 135
Query: 137 VIKAEHVVVPIVAFN-KHRQMINLAESKAS--LAAILEHSLFSTEQKLLAELDAIIGKKG 193
VVVP+ ++ + R+ + K + L+ I ++S F TE +L+ + D I GK G
Sbjct: 136 EESLSEVVVPMPSWLIRTRESVTDDPQKFAMELSIIYKYSPFKTEAELMQQFDVIYGKCG 195
Query: 194 TRIIIWNLRSYKNAT-EFDFEKDKYDIRIPEDLDEITGKKGYKKQERMDQIAPESDYSLR 252
T ++I+NL+ N E D + DK DI + L++ + ++ + P ++
Sbjct: 196 TLLVIYNLKLLLNGEPELDVKTDKEDILMAGALEDFPARWSFRAYTSVLYFNPWMRIFIQ 255
Query: 253 A-------YCSILYLKPRMQI--------------------------ILRGQKVKTQLVS 279
A C LY +PR + IL+ ++K
Sbjct: 256 AKRVKTKHLCYCLY-RPRKYLYVTSSFKGAFKDEVKKAEEAVKIAESILKEAQIKVNQCD 314
Query: 280 KSLAYIERDVY------------------RPKFLSKTVRITFGFNCRNKDHYGIMMYHRN 321
++ +DV R ++T+ + +G N N+ G+ +Y N
Sbjct: 315 RTSLSSAKDVLQRALEDVEAKQKNLKEKQRELKTARTLSLFYGVNVENRSQAGMFIYSNN 374
Query: 322 RLIKAYEKVGCQLRANN-MGVGVVGI--IECNFLKPTHNKQDFDYTNEYRLTITALGEKL 378
RLIK +EKVG QL+ + +G GVVGI I ++P+HNKQ+F EY + +G+ L
Sbjct: 375 RLIKMHEKVGSQLKLKSLLGAGVVGIVNIPLEVMEPSHNKQEFLNVQEYNHLLKVMGQYL 434
Query: 379 NDYWNEMKVKK------------NTEYPLNLPVEDIQKRPDQTW-----VQCDACLKWRK 421
Y + + + + P+ Q + Q +QCD CLKWR
Sbjct: 435 VQYCKDTGINNRNLTLFCNEFGYQNDIDVEKPLNSFQYQRRQAMGIPFIIQCDLCLKWRV 494
Query: 422 LPDGMDQLPEK----WYCSNNPDPQFRNCEVPEEPEDEDLVHPTYEKTYKKTNKEKFRIR 477
LP + ++ W C+NNP+ +C
Sbjct: 495 LPSSTNYQEKEFFDIWICANNPNRLENSC------------------------------H 524
Query: 478 QPEMIPRINAELLFRPTALSTPSFSSPKESVPRRHLSEGTNSYATRLLNNHQVPPQSEPE 537
Q E +P I L T S SP ++ + L E Y RL P +
Sbjct: 525 QVECLPSI---------PLGTMSTISPSKNEKEKQLRESVIKYQNRLAEQQPQPQFIPVD 575
Query: 538 SNSLKRRLSTRSSILNAKNRRLS-----------SQFENSVYKG------DDDDEDVIIL 580
++ T + N K +++ S FE S + ++ D DV +
Sbjct: 576 EITVTSTCLTSAHKENTKTQKIRLLGDDLKHESLSSFELSASRRGQKRNIEETDSDVEYI 635
Query: 581 EENSTPKPAVDHDIDMKSEQSHV 603
E K +++ M S+Q +
Sbjct: 636 SETKIMKKSMEE--KMNSQQQRI 656
>gi|7662340 MORC family CW-type zinc finger 2 [Homo sapiens]
Length = 970
Score = 121 bits (304), Expect = 3e-27
Identities = 156/678 (23%), Positives = 283/678 (41%), Gaps = 89/678 (13%)
Query: 297 KTVRITFGFNCRNKDHYGIMMYHRNRLIKAYEKVGCQLRANNMGVGVVGIIECNF--LKP 354
K + FG N ++D G+ +Y+ +RLIK YEKVG QL GVVG+++ + L+P
Sbjct: 302 KELNFVFGVNIEHRDLDGMFIYNCSRLIKMYEKVGPQLEGGMACGGVVGVVDVPYLVLEP 361
Query: 355 THNKQDFDYTNEYRLTITALGEKLNDYWNEMKVKK---------------NTEYPLNLPV 399
THNKQDF EYR + A+GE L YW ++ + + N P + +
Sbjct: 362 THNKQDFADAKEYRHLLRAMGEHLAQYWKDIAIAQRGIIKFWDEFGYLSANWNQPPSSEL 421
Query: 400 EDIQKRPDQ--TWVQCDACLKWRKLPDGMDQL----PEKWYCSNNPDPQFRNCEVPEEPE 453
++R + T +QCD CLKWR LP + + P+ W CS NPDP+ CE E+ +
Sbjct: 422 RYKRRRAMEIPTTIQCDLCLKWRTLPFQLSSVEKDYPDTWVCSMNPDPEQDRCEASEQKQ 481
Query: 454 DEDLVHPTYEKTYK-------------KTNKEKFRIRQPEMIPRINAELLFRPTALST-P 499
L T+ K K + +EK Q R A+L P ++T P
Sbjct: 482 KVPL--GTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQADLKKLPLEVTTRP 539
Query: 500 SFSSPKESVPRRHLSEGTNSYATRLLNNHQVPPQSEPESNSLKRRLSTRSSILNAKNRRL 559
S P P+R S + + P P S K + + + L A L
Sbjct: 540 STEEPVRR-PQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVISSTPKLPA----L 594
Query: 560 SSQFENSVYKGDDDDEDVIILEENSTPKPAVDHDIDMKSEQSHVEQGGVQVEFVGDSEPC 619
+++ E S + +L+ P+ + + S + + Q + + +S+
Sbjct: 595 AAREEASTSR---------LLQPPEAPRKPANTLVKTASRPAPLVQ-QLSPSLLPNSKSP 644
Query: 620 GQTGSTSTSSSRCDQGN------TAATQTEVPSLVVKKEETVEDEIDVRNDAVILPSCVE 673
+ S + + + AT + S+ V EE VE+E + R + V
Sbjct: 645 REVPSPKVIKTPVVKKTESPIKLSPATPSRKRSVAVSDEEEVEEEAERRKERCKRGRFVV 704
Query: 674 AEAKIHETQETTDKSADDAGCQLQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQ--QRI 731
E K ++ E +D + ++ L+ + L E + N + +T ++ ++ + +
Sbjct: 705 KEEK-KDSNELSDSAGEEDSADLKRAQKDKGLHVEVRVNRE----WYTGRVTAVEVGKHV 759
Query: 732 LEMNDK--YVKKETCHQ----STETDAVFLLESINGKSESPDH--MVSQYQQALEEIERL 783
+ K YV +T + ++ V L+ K SP+H + +Q + EE+ +
Sbjct: 760 VRWKVKFDYVPTDTTPRDRWVEKGSEDVRLM-----KPPSPEHQSLDTQQEGGEEEVGPV 814
Query: 784 KKQCSAL-QHVKAECSQCS-NNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEVELLE 841
+Q A+ + +EC + + + S E L + R + + S+ +L
Sbjct: 815 AQQAIAVAEPSTSECLRIEPDTTALSTNHETIDLLVQILRNCLRYFLPPSFPISKKQLSA 874
Query: 842 MEKSQ-----IRSQCEELKTEVEQLKSTNQQTATDVSTSS--NIEESVNHMDGESLKLRS 894
M + ++ ++ + ++ L ++ Q A + +S ++ S + KL+
Sbjct: 875 MNSDELISFPLKEYFKQYEVGLQNLCNSYQSRADSRAKASEESLRTSERKLRETEEKLQK 934
Query: 895 LRVNVGQLLAMIVPDLDL 912
LR N+ LL + D+D+
Sbjct: 935 LRTNIVALLQKVQEDIDI 952
Score = 119 bits (298), Expect = 1e-26
Identities = 82/240 (34%), Positives = 127/240 (52%), Gaps = 27/240 (11%)
Query: 63 LTFTDNGNGMTSDKLHKMLSFGFSDKVTMNGHVPVGLYGNGFKSGSMRLGKDAIVFTKNG 122
L F D+G GM ++ FG S K T +G YGNG KSGSMR+GKD I+FTK
Sbjct: 2 LCFLDDGAGMDPSDAASVIQFGKSAKRTPES-TQIGQYGNGLKSGSMRIGKDFILFTKKE 60
Query: 123 ESMSVGLLSQTYLEVIKAEHVVVPIVAFN-KHRQMI--NLAESKASLAAILEHSLFSTEQ 179
++M+ LS+T+ E + V+VP+ +N + R+ + N+ + I ++S F TE+
Sbjct: 61 DTMTCLFLSRTFHEEEGIDEVIVPLPTWNARTREPVTDNVEKFAIETELIYKYSPFRTEE 120
Query: 180 KLLAELDAIIGKKGTRIIIWNLRSYKNA-TEFDFEKDKYDIRIPEDLDEITGKKGYKKQE 238
+++ + I G GT +II+NL+ N E D + DI++ E T +G K +
Sbjct: 121 EVMTQFMKIPGDSGTLVIIFNLKLMDNGEPELDIISNPRDIQMAE-----TSPEGTKPER 175
Query: 239 RMDQIAPESDYSLRAYCSILYLKPRMQIILRGQKVKTQLVSKSLAYIERDVYRPKFLSKT 298
R S RAY ++LY+ PRM+I + G KV+T+ +S L Y+P+ T
Sbjct: 176 R----------SFRAYAAVLYIDPRMRIFIHGHKVQTKRLSCCL-------YKPRMYKYT 218
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 64.7 bits (156), Expect = 4e-10
Identities = 87/451 (19%), Positives = 187/451 (41%), Gaps = 45/451 (9%)
Query: 519 SYATRLLNNHQVPPQSEPESNSLKRRLSTRSSILNAKNRRLSSQFEN--SVYKGDDDDED 576
SY+ + + + Q+ ++ ++ S+ L ++N L + + + YK ++D
Sbjct: 611 SYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLELKEKMKELATTYKQMENDIQ 670
Query: 577 VIILEENSTPKPAVDHDIDMKSEQSHVEQ------GGVQVEFVGDSEPCGQTGSTSTSSS 630
+ + + K VD + +++S + + + G V + + + E G+ +
Sbjct: 671 LYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKITDLQKELN 730
Query: 631 RCDQGNTAATQTEV--------PSLVVKKEETVEDE-----IDVRNDAVILPSCVEAEAK 677
+ + N A + + PS V + + ++D+ I + V E++
Sbjct: 731 KEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESR 790
Query: 678 IHETQETTDKSADDAGCQLQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDK 737
+ E K+ DD L ++ +E +N+K F + K++ + MN +
Sbjct: 791 VQGLLEEIGKTKDD----LATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQE 846
Query: 738 YVKKETCHQSTETDAVFLLESINGKSESPDHMVSQYQQALEEIERLKKQC----SALQHV 793
V Q ++ L ++ K++ + Q+ L E+E+LK+Q S LQ V
Sbjct: 847 IVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTV 906
Query: 794 KAECSQCSN--NESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEV-ELLEME---KSQI 847
+ E + + ++ E+ + + DD+ + + IERDQ KS++ + + M + Q+
Sbjct: 907 EREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQL 966
Query: 848 RSQCEELKTEVEQLKSTNQQTATDVSTSSNIEESVNHMDGESLKLRSLRVNVGQLLAMIV 907
R+ E LK E + + + + +VS + ++EE+ E Q + I
Sbjct: 967 RNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDE----------FQQKMVGID 1016
Query: 908 PDLDLQQVNYDVDVVDEILGQVVEQMSEISS 938
DL+ N D +++EQ +I S
Sbjct: 1017 KKQDLEAKNTQTLTADVKDNEIIEQQRKIFS 1047
Score = 52.8 bits (125), Expect = 2e-06
Identities = 94/523 (17%), Positives = 213/523 (40%), Gaps = 71/523 (13%)
Query: 450 EEPEDEDLVHPTYEKTYKKTNKEKFRIRQPEMIPRINAELLFRPTALSTPSFSSPKESVP 509
+E ++ +H +E+ YK +E R+ Q I ++ E ++L + S
Sbjct: 817 QEFQNFKTLHMDFEQKYKMVLEENERMNQE--IVNLSKEAQKFDSSLGA---LKTELSYK 871
Query: 510 RRHLSEGTNSYATRLLNNHQVPPQSEPESNSLKRRLSTRSSILNAKNRRLSSQFENSVYK 569
+ L E T RL Q+ Q E ++L+ + +++ K ++ + + +
Sbjct: 872 TQELQEKTREVQERLNEMEQLKEQLENRDSTLQT-VEREKTLITEKLQQTLEEVKTLTQE 930
Query: 570 GDD---------DDEDVIILEENSTPKPAVDHDIDMKSEQSHVEQGGVQVEFVGDSEPCG 620
DD + D + + + T +D +++ ++Q + +
Sbjct: 931 KDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKI--- 987
Query: 621 QTGSTSTSSSRCDQGNTAATQTEVPSLVVKKEETVEDEIDVRNDAVILPSCVEAEAKIHE 680
S S + + NT T+ E +V ++ + +++ +N + A+ K +E
Sbjct: 988 ---SEEVSRNLHMEENTGETKDEFQQKMVGIDK--KQDLEAKNTQTLT-----ADVKDNE 1037
Query: 681 TQETTDK--SADDAGCQLQELRNQLL-----LVTEEKENYK------RQCHMFTDQIKVL 727
E K S +LQ++ ++ L T+ KEN + + + D++K
Sbjct: 1038 IIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQ 1097
Query: 728 QQRILEMNDKYVKKE-----TCHQSTETDAVFLLESINGKSESPDHMVSQYQQALEEIER 782
Q+ + + + +KKE TC + E + E + KS+ Q EE+
Sbjct: 1098 QEIVAQEKNHAIKKEGELSRTCDRLAEVE-----EKLKEKSQQLQEKQQQLLNVQEEMSE 1152
Query: 783 LKKQCSALQHVKAEC--SQCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEVELL 840
++K+ + ++++K E + + ++E E+A +L++ + ++ + ER K +
Sbjct: 1153 MQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSF 1212
Query: 841 EMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEESVNHMDGESLKLRSLRVNVG 900
E E+ +R E++ AT + T ++ + H+ + LR +V
Sbjct: 1213 ETERDHLRGYIREIE-------------ATGLQTKEELKIAHIHLKEHQETIDELRRSVS 1259
Query: 901 QLLAMIVPDLDLQ----QVNYDVDVVDEILGQVVEQMSEISST 939
+ A I+ DL+ ++ ++ V+ E +++ + E+S T
Sbjct: 1260 EKTAQIINTQDLEKSHTKLQEEIPVLHE-EQELLPNVKEVSET 1301
Score = 39.3 bits (90), Expect = 0.017
Identities = 86/471 (18%), Positives = 184/471 (39%), Gaps = 63/471 (13%)
Query: 455 EDLVHPTYEKTYKKTNK---EKFRIRQPEMIPRINAELLFRPTALSTPSFSSPKESVPRR 511
++L EKT + N EK + E IP ++ E P + S +E++
Sbjct: 1252 DELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLP---NVKEVSETQETMNEL 1308
Query: 512 HL--SEGTNSYATRL---------LNNHQVPPQSEPESNSLKR-RLSTRSSILNAKNRRL 559
L + T +T L LN Q E +S + +R L T L K+ +L
Sbjct: 1309 ELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQL 1368
Query: 560 SSQFENSVYKGDDD----DEDVIILEENSTPKPAVDHDIDMKSEQSHVEQGGVQVEFVGD 615
++ K + ++ + + E+++ V K + S + + +++E +G
Sbjct: 1369 KEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLR--IEIEMLGL 1426
Query: 616 SEPCGQTGST--STSSSRCD-QGNTAATQTEVPSLVVKKEETVEDEIDVRNDAVILPSCV 672
S+ ++ S + + D Q Q+E L +E V ++ + + C+
Sbjct: 1427 SKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCL 1486
Query: 673 EAEAKIHETQETTDKSADDAGCQLQELRNQLLLVTEEKEN-----YKRQCHMFTDQIKVL 727
+ + ET + + ++ ++ QL + ++ +N Y+++ QI +
Sbjct: 1487 KEQ---EETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEV 1543
Query: 728 QQRILEMN---DKYVKKETCHQSTETDAVFLLESINGKSESPDHMVSQ------YQQALE 778
Q+++ E+ + K++ QS E+ + L + E M+ + Q+AL+
Sbjct: 1544 QEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQ 1603
Query: 779 -EIERLKKQCSALQHVKAECSQ------------------CSNNESKSEMDEMAVQLDDV 819
E ++LK+ + E + C K + + + L+++
Sbjct: 1604 IERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENI 1663
Query: 820 FRQLDKCSIERDQYKSEVELLEMEKSQIRSQCEELKTEVEQLKSTNQQTAT 870
+ + + + E+ + E+ +RS E LK E +QLK ++T T
Sbjct: 1664 ETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETIT 1714
Score = 38.9 bits (89), Expect = 0.023
Identities = 49/253 (19%), Positives = 98/253 (38%), Gaps = 30/253 (11%)
Query: 626 STSSSRCDQGNTAAT-QTEVPSLVVKKEETVEDEIDVRNDAVILPSCVEAEAKIHETQET 684
S + R D + T + E L ET+ +++ + + I+ + E QET
Sbjct: 1683 SVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIV------HMHLKEHQET 1736
Query: 685 TDKSADDAGCQLQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETC 744
DK + E+ N + + K Q +++++ + E + K
Sbjct: 1737 IDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDK---- 1792
Query: 745 HQSTETDAVFLLESINGKSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECSQCSNNE 804
L ++ K++ +M + + +++ ++ A +H + N
Sbjct: 1793 ----------LRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNET 1842
Query: 805 SK--SEMDEMAVQLDDVFRQLDKCSIER-------DQYKSEVELLEMEKSQIRSQCEELK 855
K SEM+++ Q+ D L K IE + E++ + E+ +R E LK
Sbjct: 1843 QKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLK 1902
Query: 856 TEVEQLKSTNQQT 868
E +QLK + Q+T
Sbjct: 1903 LERDQLKESLQET 1915
Score = 32.0 bits (71), Expect = 2.8
Identities = 44/228 (19%), Positives = 96/228 (42%), Gaps = 42/228 (18%)
Query: 673 EAEAKIHETQETTDKSADDAGCQLQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRIL 732
E +I + Q+ DKS D+ ++QEL+ + L + KE+ + + ++I
Sbjct: 1949 EKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKED-----------VNMSHKKIN 1997
Query: 733 EMNDKYVKKETCHQSTETDAVFLLESINGKSESPDH--MVSQYQQALEEIERLKKQCSAL 790
EM + +KK+ F ++++ +S D+ + + ++LEEI + K+ L
Sbjct: 1998 EM--EQLKKQ-----------FEAQNLSMQSVRMDNFQLTKKLHESLEEIRIVAKERDEL 2044
Query: 791 QHVKAECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEVELL----EMEKSQ 846
+ +K K E D+ L R++ + Q K E LL +
Sbjct: 2045 RRIK--------ESLKMERDQFIATL----REMIARDRQNHQVKPEKRLLSDGQQHLTES 2092
Query: 847 IRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEESVNHMDGESLKLRS 894
+R +C +K +++ + S ++E+ + S+++++
Sbjct: 2093 LREKCSRIKELLKRYSEMDDHYECLNRLSLDLEKEIEFQKELSMRVKA 2140
>gi|7705415 hook homolog 1 [Homo sapiens]
Length = 728
Score = 57.8 bits (138), Expect = 5e-08
Identities = 61/271 (22%), Positives = 116/271 (42%), Gaps = 40/271 (14%)
Query: 631 RCDQGNTAAT--QTEVPSLVVKKEETVEDEIDVRNDAVILPSCVEAEAKIHETQETTDKS 688
RC++ + T Q E SLV + E + +++D + + P+ V A+ H
Sbjct: 200 RCEELDMQVTTLQDEKNSLV-SENEMMNEKLDQLDGSFDDPNTVVAKKYFH--------- 249
Query: 689 ADDAGCQLQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQST 748
A QL++L+ + + K++Y+ C Q+ Q R E+ + +ET
Sbjct: 250 ---AQLQLEQLQEENFRLEAAKDDYRVHCEELEKQLIEFQHRNDELTS--LAEETRALKD 304
Query: 749 ETDAVFLLESINGKSESPDHMVSQYQQALEEIERLKKQCSALQHV--------------- 793
E D +L + + K+ + V Y+Q L+++ L+KQ LQ
Sbjct: 305 EID---VLRATSDKANKLESTVEIYRQKLQDLNDLRKQVKTLQETNMMYMHNTVSLEEEL 361
Query: 794 -KAECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEVELLEMEKSQIRSQCE 852
KA ++ K ++ ++ V+L ++ D + E + + + E L EK ++ Q +
Sbjct: 362 KKANAARTQLETYKRQVQDLHVKLSSESKRADTLAFEMKRLEEKHEALLKEKERLIEQRD 421
Query: 853 ELKTEVEQLKSTNQQ----TATDVSTSSNIE 879
LK E+L+ + Q TD S + + E
Sbjct: 422 TLKETNEELRCSQVQQDHLNQTDASATKSYE 452
Score = 35.8 bits (81), Expect = 0.19
Identities = 37/209 (17%), Positives = 89/209 (42%), Gaps = 20/209 (9%)
Query: 695 QLQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTETDAVF 754
QL+ +L EKE +++C Q+ LQ E N + E ++
Sbjct: 179 QLKRALEELQEALAEKEELRQRCEELDMQVTTLQD---EKNSLVSENEMMNEK------- 228
Query: 755 LLESINGKSESPDHMVS-QYQQALEEIERLKKQCSALQHVKAECSQCSNNESKSEMDEMA 813
L+ ++G + P+ +V+ +Y A ++E+L++ ++ + E ++ E+++
Sbjct: 229 -LDQLDGSFDDPNTVVAKKYFHAQLQLEQLQE-----ENFRLEAAKDDYRVHCEELEKQL 282
Query: 814 VQLDDVFRQLDKCSIERDQYKSEVELLEM---EKSQIRSQCEELKTEVEQLKSTNQQTAT 870
++ +L + E K E+++L + +++ S E + +++ L +Q T
Sbjct: 283 IEFQHRNDELTSLAEETRALKDEIDVLRATSDKANKLESTVEIYRQKLQDLNDLRKQVKT 342
Query: 871 DVSTSSNIEESVNHMDGESLKLRSLRVNV 899
T+ + ++ E K + R +
Sbjct: 343 LQETNMMYMHNTVSLEEELKKANAARTQL 371
Score = 30.4 bits (67), Expect = 8.1
Identities = 51/304 (16%), Positives = 123/304 (40%), Gaps = 30/304 (9%)
Query: 640 TQTEVPSLVVKKEETVEDEIDVRNDAVILPSCVEAEAK-IHETQETTDKSADDAGCQLQE 698
T E + + ++E+E+ N A + + + +H + K AD +++
Sbjct: 342 TLQETNMMYMHNTVSLEEELKKANAARTQLETYKRQVQDLHVKLSSESKRADTLAFEMKR 401
Query: 699 LRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFLLES 758
L + + +EKE +Q L++ E+ V+++ +Q T+ A E+
Sbjct: 402 LEEKHEALLKEKER-------LIEQRDTLKETNEELRCSQVQQDHLNQ-TDASATKSYEN 453
Query: 759 INGKSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQLDD 818
+ + + M +Y++ ++ K Q + S NE ++E+ QL+
Sbjct: 454 L-----AAEIMPVEYREVFIRLQHENKMLRLQQ-------EGSENE---RIEELQEQLEQ 498
Query: 819 VFRQLDKCSIERDQYKSEVELLEMEKSQIRSQCEE--LKTEVEQLKSTNQQTATDVSTSS 876
R++++ E+ K + L+ + ++ +E K+E E Q+ + +
Sbjct: 499 KHRKMNELETEQRLSKERIRELQQQIEDLQKSLQEQGSKSEGESSSKLKQKLEAHMEKLT 558
Query: 877 NIEESVNHMDGESLKLRSLRVNVGQLLAMIVP-DLDLQQVNYDVDVVDEILGQVVEQMSE 935
+ E + + + L+ ++ Q + I + LQ+ + D+ ++E +E+
Sbjct: 559 EVHE---ELQKKQELIEDLQPDINQNVQKINELEAALQKKDEDMKAMEERYKMYLEKARN 615
Query: 936 ISST 939
+ T
Sbjct: 616 VIKT 619
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 54.3 bits (129), Expect = 5e-07
Identities = 75/355 (21%), Positives = 151/355 (42%), Gaps = 62/355 (17%)
Query: 639 ATQTEVPSLVVKKEETVEDEIDVRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQE 698
A Q ++ S V KE V+ D ++ S + E ++ + E+ K + +
Sbjct: 513 AAQQDLQSKFVAKENEVQSLHSKLTDTLV--SKQQLEQRLMQLMESEQKRVNKE----ES 566
Query: 699 LRNQLLLVTEEKENYKRQCHMFTDQI------KVLQQ---RILEMNDKYVKKETCHQSTE 749
L+ Q+ + E+ E K Q F QI VL + +++ DK +K+ ++E
Sbjct: 567 LQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASE 626
Query: 750 TDAV--------------FLL-------ESINGKSESPDHMVSQYQQAL----EEIERLK 784
D + FLL +++ + + H + + QQ++ ++I L+
Sbjct: 627 RDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLE 686
Query: 785 KQCSALQHVKAECSQCSNNESK---SEMDEMAVQLD-----DVFRQLDKCSIERDQYKSE 836
+Q K E + N+++K SE+ ++ + DV Q++KC E+D+
Sbjct: 687 EQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKT 746
Query: 837 VELL-----------EMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEESVNHM 885
VE L E E + IR++ L EV+ LK+ + S +++ ++
Sbjct: 747 VEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEK 806
Query: 886 DGESLKLRSLRVNVGQLLAMIVPDLDLQQVNYDVDVVDEILGQV-VEQMSEISST 939
DG+ + L +LL + + +Q + ++ + E +G V +E+ ++S T
Sbjct: 807 DGKIKSVEELL--EAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSIT 859
Score = 37.7 bits (86), Expect = 0.051
Identities = 54/290 (18%), Positives = 111/290 (38%), Gaps = 34/290 (11%)
Query: 677 KIHETQETTDKSADDAGCQLQELRNQLLLVTEEKEN--YKRQCHMFTDQIKVLQQRILEM 734
K+++T + + + + +E+ +L N Y H F + K
Sbjct: 1053 KVNKTSKERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGS 1112
Query: 735 NDKYVKKETCHQSTETDAVFLLESINGKS--ESPDHMVSQYQQALEEIERLKKQCSALQH 792
+ V + ++ E + LE KS + ++ + Q+++E+ E K H
Sbjct: 1113 EEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESH 1172
Query: 793 VKAECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEVELLEMEKSQIRSQCE 852
+ Q S S+ E++ + + D+ + ER+ + E+E EME+S ++
Sbjct: 1173 KTIKQMQSSFTSSEQELERLRSENKDI----ENLRREREHLEMELEKAEMERSTYVTEVR 1228
Query: 853 ELK---------------------TEVEQLKSTNQQTATDVSTSSNIEESVN---HMDGE 888
ELK E+ LK+ +T T + T N + V H +
Sbjct: 1229 ELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTKLRTEQNERQKVAGDLHKAQQ 1288
Query: 889 SLKLRSLRV--NVGQLLAMIVPDLDLQQVNYDVDVVDEILGQVVEQMSEI 936
SL+L ++ G + D+ + + + + + L Q V Q+ ++
Sbjct: 1289 SLELIQSKIVKAAGDTTVIENSDVSPETESSEKETMSVSLNQTVTQLQQL 1338
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 54.3 bits (129), Expect = 5e-07
Identities = 75/355 (21%), Positives = 151/355 (42%), Gaps = 62/355 (17%)
Query: 639 ATQTEVPSLVVKKEETVEDEIDVRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQE 698
A Q ++ S V KE V+ D ++ S + E ++ + E+ K + +
Sbjct: 513 AAQQDLQSKFVAKENEVQSLHSKLTDTLV--SKQQLEQRLMQLMESEQKRVNKE----ES 566
Query: 699 LRNQLLLVTEEKENYKRQCHMFTDQI------KVLQQ---RILEMNDKYVKKETCHQSTE 749
L+ Q+ + E+ E K Q F QI VL + +++ DK +K+ ++E
Sbjct: 567 LQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASE 626
Query: 750 TDAV--------------FLL-------ESINGKSESPDHMVSQYQQAL----EEIERLK 784
D + FLL +++ + + H + + QQ++ ++I L+
Sbjct: 627 RDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLE 686
Query: 785 KQCSALQHVKAECSQCSNNESK---SEMDEMAVQLD-----DVFRQLDKCSIERDQYKSE 836
+Q K E + N+++K SE+ ++ + DV Q++KC E+D+
Sbjct: 687 EQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKT 746
Query: 837 VELL-----------EMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEESVNHM 885
VE L E E + IR++ L EV+ LK+ + S +++ ++
Sbjct: 747 VEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEK 806
Query: 886 DGESLKLRSLRVNVGQLLAMIVPDLDLQQVNYDVDVVDEILGQV-VEQMSEISST 939
DG+ + L +LL + + +Q + ++ + E +G V +E+ ++S T
Sbjct: 807 DGKIKSVEELL--EAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSIT 859
Score = 41.2 bits (95), Expect = 0.005
Identities = 78/412 (18%), Positives = 160/412 (38%), Gaps = 41/412 (9%)
Query: 535 EPESNSLKRRLSTRSSILNAKNRRLSSQFENSVYKGDDDDEDVIILEENSTPKPAVDHDI 594
+ E+ SLK + + N K +SQFE E I+L+E ++
Sbjct: 901 QEENESLKAHVQEVAQH-NLKEASSASQFE----------ELEIVLKEKENELKRLE--A 947
Query: 595 DMKSEQSHVEQGGVQVEFVGDSEPCGQTGSTSTSSSRCDQGNTAATQTEVPSLVVKKEET 654
+K +S + ++ V D ++ Q ++ E+ ++ ++E+
Sbjct: 948 MLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKE 1007
Query: 655 VE---DEIDVRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQELRNQLLLVTEEKE 711
+ +E+D DAV K +E Q+ + +A L++L ++ + +
Sbjct: 1008 ISGLWNELDSLKDAV-----EHQRKKNNERQQQVEAVELEAKEVLKKLFPKVSVPSNL-- 1060
Query: 712 NYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFLLESINGKS--ESPDHM 769
+Y H F + K + V + ++ E + LE KS + +
Sbjct: 1061 SYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGI 1120
Query: 770 VSQYQQALEEIERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSIE 829
+ + Q+++E+ E K H + Q S S+ E++ + + D+
Sbjct: 1121 LQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDI---------- 1170
Query: 830 RDQYKSEVELLEMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEESVN---HMD 886
+ + E E LEME + + TEV +LK+ +T T + T N + V H
Sbjct: 1171 -ENLRREREHLEMELEKAEMERSTYVTEVRELKAQLNETLTKLRTEQNERQKVAGDLHKA 1229
Query: 887 GESLKLRSLRV--NVGQLLAMIVPDLDLQQVNYDVDVVDEILGQVVEQMSEI 936
+SL+L ++ G + D+ + + + + + L Q V Q+ ++
Sbjct: 1230 QQSLELIQSKIVKAAGDTTVIENSDVSPETESSEKETMSVSLNQTVTQLQQL 1281
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 54.3 bits (129), Expect = 5e-07
Identities = 75/355 (21%), Positives = 151/355 (42%), Gaps = 62/355 (17%)
Query: 639 ATQTEVPSLVVKKEETVEDEIDVRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQE 698
A Q ++ S V KE V+ D ++ S + E ++ + E+ K + +
Sbjct: 513 AAQQDLQSKFVAKENEVQSLHSKLTDTLV--SKQQLEQRLMQLMESEQKRVNKE----ES 566
Query: 699 LRNQLLLVTEEKENYKRQCHMFTDQI------KVLQQ---RILEMNDKYVKKETCHQSTE 749
L+ Q+ + E+ E K Q F QI VL + +++ DK +K+ ++E
Sbjct: 567 LQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASE 626
Query: 750 TDAV--------------FLL-------ESINGKSESPDHMVSQYQQAL----EEIERLK 784
D + FLL +++ + + H + + QQ++ ++I L+
Sbjct: 627 RDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLE 686
Query: 785 KQCSALQHVKAECSQCSNNESK---SEMDEMAVQLD-----DVFRQLDKCSIERDQYKSE 836
+Q K E + N+++K SE+ ++ + DV Q++KC E+D+
Sbjct: 687 EQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKT 746
Query: 837 VELL-----------EMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEESVNHM 885
VE L E E + IR++ L EV+ LK+ + S +++ ++
Sbjct: 747 VEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEK 806
Query: 886 DGESLKLRSLRVNVGQLLAMIVPDLDLQQVNYDVDVVDEILGQV-VEQMSEISST 939
DG+ + L +LL + + +Q + ++ + E +G V +E+ ++S T
Sbjct: 807 DGKIKSVEELL--EAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSIT 859
Score = 37.7 bits (86), Expect = 0.051
Identities = 54/290 (18%), Positives = 111/290 (38%), Gaps = 34/290 (11%)
Query: 677 KIHETQETTDKSADDAGCQLQELRNQLLLVTEEKEN--YKRQCHMFTDQIKVLQQRILEM 734
K+++T + + + + +E+ +L N Y H F + K
Sbjct: 1053 KVNKTSKERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGS 1112
Query: 735 NDKYVKKETCHQSTETDAVFLLESINGKS--ESPDHMVSQYQQALEEIERLKKQCSALQH 792
+ V + ++ E + LE KS + ++ + Q+++E+ E K H
Sbjct: 1113 EEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESH 1172
Query: 793 VKAECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEVELLEMEKSQIRSQCE 852
+ Q S S+ E++ + + D+ + ER+ + E+E EME+S ++
Sbjct: 1173 KTIKQMQSSFTSSEQELERLRSENKDI----ENLRREREHLEMELEKAEMERSTYVTEVR 1228
Query: 853 ELK---------------------TEVEQLKSTNQQTATDVSTSSNIEESVN---HMDGE 888
ELK E+ LK+ +T T + T N + V H +
Sbjct: 1229 ELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTKLRTEQNERQKVAGDLHKAQQ 1288
Query: 889 SLKLRSLRV--NVGQLLAMIVPDLDLQQVNYDVDVVDEILGQVVEQMSEI 936
SL+L ++ G + D+ + + + + + L Q V Q+ ++
Sbjct: 1289 SLELIQSKIVKAAGDTTVIENSDVSPETESSEKETMSVSLNQTVTQLQQL 1338
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 53.9 bits (128), Expect = 7e-07
Identities = 37/195 (18%), Positives = 99/195 (50%), Gaps = 9/195 (4%)
Query: 673 EAEAKIHETQETTDKSADDAGCQLQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRIL 732
E E ++ E +E K + G Q +++R Q + E++E ++Q +Q++ ++++
Sbjct: 203 EQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQ----EEQVQKQEEQMR 258
Query: 733 EMNDKYVKKETCHQSTETDAVFLLESINGKSESPDHMVSQYQQALEEIERLKKQCSALQH 792
+ ++ ++E Q E + L + ++E + Q +Q E+ E++++Q ++
Sbjct: 259 KQEEQMREQE--EQMREQEEQMLKQK--EQTEQEEQTGEQEEQMREQEEQMREQEEQMRE 314
Query: 793 VKAECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEVELLEMEKSQIRSQCE 852
+ + + K E ++M Q + ++ Q ++ + +Q + E ++ ++ Q+R Q E
Sbjct: 315 QEEQMREQEEQMGKQE-EQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEE 373
Query: 853 ELKTEVEQLKSTNQQ 867
+++ + EQ++ +Q
Sbjct: 374 QMRKQEEQMRKQEEQ 388
Score = 50.8 bits (120), Expect = 6e-06
Identities = 46/230 (20%), Positives = 104/230 (45%), Gaps = 18/230 (7%)
Query: 675 EAKIHETQETTDKSADDAGCQLQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEM 734
E ++ E +E K + G Q ++++ Q V +++E ++Q +Q++ ++++ E
Sbjct: 219 EEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQ----EEQMREQEEQMREQ 274
Query: 735 NDKYVK-KETCHQSTET--DAVFLLESINGKSESPDHMVSQYQQALEEIERLKKQCSALQ 791
++ +K KE Q +T + E E + M Q +Q E+ E++ KQ +
Sbjct: 275 EEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMW 334
Query: 792 HVKAECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEVELLEMEKSQIRSQC 851
K + E K +M + Q+ + Q+ K + +Q + + E + ++ Q+R Q
Sbjct: 335 EQKEQMW-----EQKEQMWKQEEQMGEQEEQMQK---QEEQVRKQEEQMRKQEEQMRKQE 386
Query: 852 EELKTEVEQLKSTNQQTATDVSTSSNIEESVNHMDGESLKLRSLRVNVGQ 901
E+++ + EQ+ +Q + E M + ++R ++G+
Sbjct: 387 EQMRKQEEQMGEQKEQMG---EQKEQMREQEEQMGEQKEQMRKQEEHMGE 433
Score = 37.7 bits (86), Expect = 0.051
Identities = 39/208 (18%), Positives = 86/208 (41%), Gaps = 22/208 (10%)
Query: 673 EAEAKIHETQETTDKSADDAGCQLQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRIL 732
E E ++ E + + Q ++R Q V E++ + Q Q++ + ++
Sbjct: 112 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ----EGQVREQEGQVR 167
Query: 733 EMNDKYVKKETCHQSTETDAVFLLESINGKSESPDHMVSQYQQALEEIERLKKQCSALQH 792
E + ++E + E + E E M Q +Q E+ E+++KQ +
Sbjct: 168 EQEGQVREQEGQVREQEGQ---VREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQM-- 222
Query: 793 VKAECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEVELLEMEKSQIRSQCE 852
E + +M + Q+ + Q+ K + +Q + + E + ++ Q+R Q E
Sbjct: 223 ----------GEQEEQMRKQEEQMGEQEEQVQK---QEEQVQKQEEQMRKQEEQMREQEE 269
Query: 853 ELKTEVEQLKSTNQQTATDVSTSSNIEE 880
+++ + EQ+ +QT + T E+
Sbjct: 270 QMREQEEQMLKQKEQTEQEEQTGEQEEQ 297
>gi|112420968 coiled-coil domain containing 158 [Homo sapiens]
Length = 1113
Score = 53.9 bits (128), Expect = 7e-07
Identities = 70/328 (21%), Positives = 146/328 (44%), Gaps = 44/328 (13%)
Query: 622 TGSTSTSSSRCDQGNTAATQTEVPSLVVKKEETVEDEIDVRNDAVILPSCVEAEAKIHET 681
TG T +SS Q N+ +Q E+ ++++ ++ + +R + + + + +++ E
Sbjct: 281 TGLTEKASSARSQANSIQSQMEI----IQEQARNQNSMYMRQLSDLESTVSQLRSELREA 336
Query: 682 QETTDKSADDAGCQLQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKK 741
+ + ++ QL ++L E++ + ++ DQ LQ+ + +++ + +K
Sbjct: 337 KRMYEDKTEELEKQLVLANSELTEARTERDQFSQESGNLDDQ---LQKLLADLHKR--EK 391
Query: 742 ETCHQSTETDAVFLLESINGKSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECSQCS 801
E + + ++ + G S + DH+ + E++RL+ AL K+EC
Sbjct: 392 ELSLEKEQNKRLW--DRDTGNSITIDHLRRELDNRNMEVQRLEALLKAL---KSEC---- 442
Query: 802 NNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEVELLEMEKSQIRSQCEELKTEVEQL 861
+ +M+ + L+K S S LE K +R EEL + L
Sbjct: 443 ----QGQMERQMAAIQGKNESLEKVS-------SLTAQLESTKEMLRKVVEELTAKKMTL 491
Query: 862 KSTNQQTATDVSTS-SNIEESVNHMDGESLKLRSLRV-----------NVGQLLAMIVPD 909
+S +++T +D++TS E ++ + E KLRS RV N G L + +
Sbjct: 492 ES-SERTISDLTTSLQEKERAIEATNAEITKLRS-RVDLKLQELQHLKNEGDHLRNVQTE 549
Query: 910 LDLQQVNY-DVDVVDEILGQVVEQMSEI 936
+ ++ + D V EIL Q +E M+++
Sbjct: 550 CEALKLQMTEKDKVIEILRQQIENMTQL 577
Score = 40.0 bits (92), Expect = 0.010
Identities = 72/375 (19%), Positives = 144/375 (38%), Gaps = 28/375 (7%)
Query: 533 QSEPESNSLKRRLSTRSSILNAKNRRLSSQFENSVYKGDDDDEDVIILEENSTPKPAVDH 592
Q ES +L +L + L+ + + LS + E + D D + I ++ +
Sbjct: 367 QFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDNRNM 426
Query: 593 DID--------MKSE-QSHVEQGGVQVEFVGDSEPCGQTGSTSTSSSRCDQGNTAATQTE 643
++ +KSE Q +E+ ++ +S SS +T +
Sbjct: 427 EVQRLEALLKALKSECQGQMERQMAAIQGKNES-------LEKVSSLTAQLESTKEMLRK 479
Query: 644 VPSLVVKKEETVEDEIDVRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQELRN-- 701
V + K+ T+E +D + S E E I T K +LQEL++
Sbjct: 480 VVEELTAKKMTLESSERTISD--LTTSLQEKERAIEATNAEITKLRSRVDLKLQELQHLK 537
Query: 702 ----QLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFLLE 757
L V E E K Q I++L+Q+I M + + + + L +
Sbjct: 538 NEGDHLRNVQTECEALKLQMTEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEK 597
Query: 758 SINGKSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQLD 817
IN + + + +I L+ + S L+ K + + ++ D + + D
Sbjct: 598 EINDRRMELKELKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKD-IKQERD 656
Query: 818 DVFRQLDKCSIERDQYKSEVELLEMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSN 877
+ ++ E + E E+L K R++ EE++ +LK + +++ + N
Sbjct: 657 QLLNEVKTSRSELNNLSEEYEVL---KRNFRNKSEEMEMTTNKLKMQLKSAQSELEQTRN 713
Query: 878 IEESVNHMDGESLKL 892
+S+ DG ++K+
Sbjct: 714 TLKSMEGSDGHAMKV 728
Score = 32.0 bits (71), Expect = 2.8
Identities = 30/145 (20%), Positives = 65/145 (44%), Gaps = 13/145 (8%)
Query: 710 KENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFLLESINGKSESPDHM 769
KE+++R ++ Q+K LQ+R+ E N+ + K++ + + D L+ + + D M
Sbjct: 73 KEHFERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMER---DAM 129
Query: 770 VSQYQQALEEIERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSIE 829
++ + E L+ Q H + E ++C ++M + QL K +
Sbjct: 130 ADIRRRESQSQEDLRNQLQNTVH-ELEAAKCLK-------EDMLKDSNTQIEQLRKMMLS 181
Query: 830 RDQYKSEVE--LLEMEKSQIRSQCE 852
+ E+ L++ E++ + CE
Sbjct: 182 HEGVLQEIRSILVDFEEASGKKICE 206
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 53.9 bits (128), Expect = 7e-07
Identities = 54/272 (19%), Positives = 117/272 (43%), Gaps = 35/272 (12%)
Query: 678 IHETQETTDKSADDAGCQLQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDK 737
+ + + D D+ +LQ L QL E N K+ +F + L I ++ K
Sbjct: 119 LQQQEAKPDGLVTDSSAELQSLEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSK 178
Query: 738 YVKKETCHQSTETDAVFLLESINGKSESPDHMVSQYQQ--ALEEIERLKKQCSALQHVKA 795
Y ++ + ++ E L E +N ++ + ++ Q +E++ LKK+ +Q +
Sbjct: 179 YDEERSLREAAEQKVTRLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQVQTL-- 236
Query: 796 ECSQCSNNESKSEMDEMAVQLDDVFRQL-DKCSIERDQYKSEVELLEMEKSQIRSQCEEL 854
MD M ++ + +L D+C + QY S + +S++ +E+
Sbjct: 237 -------------MDNMTLERERESEKLKDECKKLQSQYASSEATISQLRSELAKGPQEV 283
Query: 855 KTEVEQLK----STNQQTATDVSTSSNI---EESVNHMD----GESLKLRSLRVNVGQLL 903
V++L+ S N+ T + + + N+ E+ ++ ES+ ++++ + Q
Sbjct: 284 AVYVQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQ-- 341
Query: 904 AMIVPDLDLQQVNYDVDVVDEILGQVVEQMSE 935
DLD QQ+ + + L ++ ++SE
Sbjct: 342 ----KDLDCQQLQSRLSASETSLHRIHVELSE 369
Score = 41.6 bits (96), Expect = 0.004
Identities = 83/425 (19%), Positives = 162/425 (38%), Gaps = 70/425 (16%)
Query: 533 QSEPESNSLKRRLSTRSSILNAKNRRLSSQFENSVYKGDDDDEDVIILE----------- 581
Q + E N L +L L + RL Q + S K D ++ V L+
Sbjct: 411 QLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLK 470
Query: 582 ENSTPKPAVDHDIDMKSEQSHVEQGGVQVEFVGDSEPCGQTGSTSTSSSRCDQ-----GN 636
E T + H +D K++Q H EQ +Q T + + +Q G+
Sbjct: 471 EKVTNSTELQHQLD-KTKQQHQEQQALQQS---------TTAKLREAQNDLEQVLRQIGD 520
Query: 637 TAATQTEVPSLVVKKEETVEDEIDVRNDAVILPSCVEAE-AKIHETQETTDKSADDAGCQ 695
+ +L+ K +E + R D E E A +++ QE +
Sbjct: 521 KDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQL 580
Query: 696 LQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFL 755
++L+NQ E++K+ DQ++ + + D+ + ET
Sbjct: 581 TEKLKNQ-------SESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETS----------- 622
Query: 756 LESINGKSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQ 815
+ +N + VSQ ++ L A + + Q + +++ + + +
Sbjct: 623 VNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQE 682
Query: 816 LDDVFRQLDKCSIERDQYKSEVELLEMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTS 875
L+ + QL DQ ++++ + SQ+ S +E K E+ S Q+T
Sbjct: 683 LNKITTQL-------DQVTAKLQDKQEHCSQLESHLKEYK---EKYLSLEQKT------- 725
Query: 876 SNIEESVNHMDGESLKLRSLRVNVGQLLAMIVPDLDLQ-QVNYDVDVVDEILGQVVEQMS 934
+E + ++ +SL++++ + Q DL Q Q+N D+++ L + +E
Sbjct: 726 EELEGQIKKLEADSLEVKASKEQALQ-------DLQQQRQLNTDLELRATELSKQLEMEK 778
Query: 935 EISST 939
EI S+
Sbjct: 779 EIVSS 783
Score = 40.4 bits (93), Expect = 0.008
Identities = 79/400 (19%), Positives = 164/400 (41%), Gaps = 61/400 (15%)
Query: 513 LSEGTNSYATRLLNNHQVPPQSEPESNSLKRRLSTRSSILNAKNRRLSSQFENSVYKGDD 572
LS+ T L N Q + K L T S + K ++S +NS + +
Sbjct: 819 LSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEK 878
Query: 573 DDED--VIILEENSTPKPAVDHDIDMKSEQSHVEQGGVQVEFVGDSEPCGQTG-STSTSS 629
+++ IL+ T K + H + ++ E + EQ ++ + E Q ++
Sbjct: 879 ENQKGKAAILDLEKTCKE-LKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQ 937
Query: 630 SRCDQGNTAATQTEVPSLVVKKEETVEDEI-DVRNDAVILPSCVEA---EAKIHETQETT 685
+ Q Q E K+E+ ++ I +++ + +EA E KI Q+T
Sbjct: 938 EQLIQAQNTLKQNE------KEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTE 991
Query: 686 DKSADDAGCQLQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCH 745
++ +L+ QL +E K + + + + Q+ ++ + +E+
Sbjct: 992 LEN---------KLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESEL 1042
Query: 746 QSTETDAVFLLESINGKSE---SPDHMVSQYQQALEEI---------------ERLKKQC 787
+T D + E ++ E S + + + ++E+ ++L+++C
Sbjct: 1043 LATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERC 1102
Query: 788 SALQHVKAECS----QCSNNESK-SEMDEMAVQLDDVFRQLDKCSIERDQYKSE------ 836
ALQ ++ E S + N +SK +E++E+ + + +++ K + E +K E
Sbjct: 1103 KALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQE---KEITKLNEELKSHKLESIKEIT 1159
Query: 837 -----VELLEMEKSQIRSQCEELKTEVEQLKSTNQQTATD 871
+LL +K +++ + + LK VEQ K NQQ D
Sbjct: 1160 NLKDAKQLLIQQKLELQGKADSLKAAVEQEK-RNQQILKD 1198
Score = 40.0 bits (92), Expect = 0.010
Identities = 45/235 (19%), Positives = 92/235 (39%), Gaps = 29/235 (12%)
Query: 677 KIHETQETTDKSADDAGCQLQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMND 736
K+ +++ + +L + ++ + +E + K + T + + L + +L+
Sbjct: 257 KLQSQYASSEATISQLRSELAKGPQEVAVYVQELQKLKSSVNELTQKNQTLTENLLKKEQ 316
Query: 737 KYVKKETCHQSTETDAVFLLESINGK-------------SESPDHMVS-QYQQALEEIER 782
Y K E H + +++ K SE+ H + + + E ++
Sbjct: 317 DYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQK 376
Query: 783 LKKQCSAL----QHVKAECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEVE 838
LK++ S + QH+KAE Q + + E ++ +QL QL +E ++ E
Sbjct: 377 LKEELSEVETKYQHLKAEFKQL--QQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAH 434
Query: 839 LLEMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEESVNHMDGESLKLR 893
E+ Q+ S E+L QQ A S +EE + S +L+
Sbjct: 435 GRLKEQRQLSS---------EKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQ 480
Score = 40.0 bits (92), Expect = 0.010
Identities = 47/258 (18%), Positives = 106/258 (41%), Gaps = 37/258 (14%)
Query: 651 KEETVEDEIDVRNDAVILPSCVEAE----AKIHETQETTDKSADDAGCQLQELRNQLLLV 706
KE+ + +I ++ +L S A+ A + +T + D +L ++ QL V
Sbjct: 634 KEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQV 693
Query: 707 TEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFLLES-------- 758
T + ++ + C +K +++ L + K + E + E D++ + S
Sbjct: 694 TAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDL 753
Query: 759 ----------------INGKSESPDHMVSQYQ-------QALEEI-ERLKKQCSALQHVK 794
++ + E +VS + +ALE I ++L KQ Q +K
Sbjct: 754 QQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILK 813
Query: 795 AECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEVELLEMEKSQIRSQCEEL 854
+ S E+K + +E+ ++ +L K +E++ +E+ ++ + S++ +
Sbjct: 814 QDFETLSQ-ETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNS 872
Query: 855 KTEVEQLKSTNQQTATDV 872
K+E E+ + D+
Sbjct: 873 KSEFEKENQKGKAAILDL 890
Score = 32.7 bits (73), Expect = 1.6
Identities = 38/185 (20%), Positives = 75/185 (40%), Gaps = 26/185 (14%)
Query: 759 INGKSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQLDD 818
+N +S S + Q ++L + L K A+ N+ +A++ DD
Sbjct: 32 VNNESSSEGFICPQCMKSLGSADELFKHYEAVH-------DAGNDSGHGGESNLALKRDD 84
Query: 819 VFRQLDKCSIERDQYKSEVELLEMEKSQIRSQCEELKTEVEQLKSTNQQTA------TDV 872
V + EV+ L+ + + EELK E+E+ + QQ A TD
Sbjct: 85 V-----------TLLRQEVQDLQASLKEEKWYSEELKKELEKYQGLQQQEAKPDGLVTDS 133
Query: 873 STS-SNIEESVNHMDGESLKLRSLRVNVGQLLAMIVPDLDLQQVNYDVD-VVDEILGQVV 930
S ++E+ + E+ ++ ++ Q A + ++ + YD + + E Q V
Sbjct: 134 SAELQSLEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQKV 193
Query: 931 EQMSE 935
+++E
Sbjct: 194 TRLTE 198
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 53.1 bits (126), Expect = 1e-06
Identities = 79/372 (21%), Positives = 153/372 (41%), Gaps = 52/372 (13%)
Query: 552 LNAKNRRLSSQFENSVYKGDDDDEDVIILEENSTPKPAVDHDIDMKSE-QSHVEQGGVQV 610
L +N+ L SQ E + + ++ LE S K D D+ + + EQ G
Sbjct: 2282 LQGENKELLSQLEETRHLYHSSQNELAKLE--SELKSLKDQLTDLSNSLEKCKEQKGNLE 2339
Query: 611 EFVGDSEPCGQTGSTSTSSSRCDQGNTAATQTEVPSLVVKKEETVEDEIDVRNDAVILPS 670
+ E Q S D + + + + KE+ + + + +A+
Sbjct: 2340 GIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAI---- 2395
Query: 671 CVEAEAKIHETQETTDKSADDAGCQLQELRNQLLLVTEEKENY--KRQCHMFTDQIKVLQ 728
+ I E ++ DK +++EL N LL EE+EN + + D+ L
Sbjct: 2396 ----QVAIAELRQQHDK-------EIKELEN--LLSQEEEENIVLEEENKKAVDKTNQLM 2442
Query: 729 QRILEMNDKYVKKETCHQSTETDAVFLLESINGKSESPDHMVSQYQQALEE-IERLKKQC 787
+ + K +KKE Q + D+ ++S++ D +V YQQ E + + ++
Sbjct: 2443 ETL-----KTIKKENIQQKAQLDS--FVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKD 2495
Query: 788 SALQHVKAECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEV---------- 837
+Q AE NN+ K E+ + +DD+ + K E QY+ ++
Sbjct: 2496 QLIQEAAAE-----NNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQ 2550
Query: 838 --ELLEMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSN-IEESVNHMDGESLKLRS 894
+LLE++ Q + E ++E+ +++ D+ S N ++E + S ++ S
Sbjct: 2551 QKQLLEVQLQQ-NKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDL---SKEIES 2606
Query: 895 LRVNVGQLLAMI 906
L+V++ QL +
Sbjct: 2607 LKVSISQLTRQV 2618
Score = 42.7 bits (99), Expect = 0.002
Identities = 74/356 (20%), Positives = 138/356 (38%), Gaps = 56/356 (15%)
Query: 564 ENSVYKGDDDDEDVIILEENSTPK-PAVDHDID----------MKSEQSHVEQGGVQVEF 612
E ++K + +LE N P P+ D +K++ +E V++E
Sbjct: 1264 EEPLFKATEQHHTQPVLESNLCPDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVELEL 1323
Query: 613 VGDSEPCGQTGSTSTSSSRCDQGNTAATQTEVPSLVVKKEETVEDEIDVRNDAVI----- 667
S +TS + + ++ Q L ++ +TV E +V +++
Sbjct: 1324 KVSS-------TTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLES 1376
Query: 668 -------LPSCVEAEAKIHETQETTDKSADDAGCQLQELRNQLLLVTEEKENYKRQCHMF 720
L E + K+ E Q+ K +D +L + +T+ + Q
Sbjct: 1377 SQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQ---- 1432
Query: 721 TDQIKVLQQRILEM----NDKYVKK---ETCHQSTETDAVFLLESINGKSESPDHMVSQY 773
D IK L + LEM +D+ +K+ E C + E I +S + + +
Sbjct: 1433 EDLIKALHTQ-LEMQAKEHDERIKQLQVELCEMKQKP------EEIGEESRAKQQIQRKL 1485
Query: 774 QQALEEIERLKKQCSALQHVKA------ECSQCSNNESKSEMDEMAVQLDDVFRQLDKCS 827
Q AL + K+ +LQ + E S + +S++ + D V +L
Sbjct: 1486 QAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQ 1545
Query: 828 IERDQYKSEVELLEMEKSQIRSQCEELKTEVEQLKSTNQQTATDVST--SSNIEES 881
ERD+ +E++ +E + S CE LK +E L ++ ++ + SS I ES
Sbjct: 1546 EERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAES 1601
Score = 39.7 bits (91), Expect = 0.013
Identities = 110/600 (18%), Positives = 217/600 (36%), Gaps = 119/600 (19%)
Query: 374 LGEKLNDYWNEMKVKKNTEYPLNLPVEDIQKRPDQTWVQCDACLKWRKLPDGMDQLPEKW 433
L E++N E++ K + + E +Q++ + + +Q R+L +D+L +K
Sbjct: 1342 LQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDEL-QKL 1400
Query: 434 YCSNNPDPQFRNCEVPEEP-----------EDEDLVHPTYEKTYKKTNKEKFRIRQ---- 478
D + + ++ E+ E EDL+ + + + + RI+Q
Sbjct: 1401 ISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVE 1460
Query: 479 -------PEMIP-----------RINAELLFRPTALSTPSFSSPKESVPRRHLSEGTNSY 520
PE I ++ A L+ R AL + S+ R + T S
Sbjct: 1461 LCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSL 1520
Query: 521 ATRLLNNHQVPPQSEPESNSLKR---------RLSTRSSILNAKNRRLSSQFENS--VYK 569
A QV Q++ + L R +L T +N+ LSS E+ +
Sbjct: 1521 ADV---ESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALE 1577
Query: 570 GDDDDEDVIILEENSTPKPAVDHDIDMKSEQSHVEQGGVQVEFVGDSEPCGQTGSTSTSS 629
G +D++ ++ E S + + + + +++ + E Q+ ++
Sbjct: 1578 GLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQK---------EYEILLQSYENVSNE 1628
Query: 630 SRCDQGNTAATQTEVPSLVVKKEETVEDEIDVRNDAVILPSCVEAEAKIHETQETTDKSA 689
+ Q A + E L K T ++ + EAE ++ E +E K A
Sbjct: 1629 AERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQ------EAEQEMEEMKEKMRKFA 1682
Query: 690 DDAGCQLQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMND-----------KY 738
+ + ++L + EE + + + H D K + +L N +Y
Sbjct: 1683 -------KSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEY 1735
Query: 739 VKKETCHQSTETDAVFLLESINGKSESPDHMVSQYQQALEEIERLKKQCSAL----QHVK 794
QS ++ L E + + VS+ Q LE E+ Q + Q +
Sbjct: 1736 ETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSK-QANLEATEKHDNQTNVTEEGTQSIP 1794
Query: 795 AECSQ-----------CSNN---------------ESKSEMDEMAVQLDDVFRQLDKCSI 828
E + CS + S E++ Q+D + ++
Sbjct: 1795 GETEEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEE 1854
Query: 829 ERDQYKSEVELLEMEKSQIRSQ-------CEELKTEVEQLKSTNQQTATDVSTSSNIEES 881
E+ + K + LE EK+ + SQ + L+ EV ++ NQQ ++S + ++E+
Sbjct: 1855 EKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKET 1914
Score = 38.5 bits (88), Expect = 0.030
Identities = 71/405 (17%), Positives = 166/405 (40%), Gaps = 39/405 (9%)
Query: 537 ESNSLKRRLSTRSSILNAKNRRLSSQFENSVYK---GDDDDEDVIILEENSTPKPAVDHD 593
++ S K T+ ++ A R +Q E + +K D E +L +N K + +
Sbjct: 2049 QTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSN 2108
Query: 594 ID-----MKSEQSHVEQGGVQVEFVGDSEPCGQTGSTSTSSSRCDQGNTAATQTEVPSLV 648
+ MK + +E+ Q E E + + R ++ + T E+ +
Sbjct: 2109 KESVKSQMKQKDEDLERRLEQAEEKHLKEK--KNMQEKLDALRREKVHLEETIGEIQVTL 2166
Query: 649 VKKEETVEDEIDVRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQELRNQLLLVTE 708
KK++ V+ ++ D+ + ++ + Q+ D+ D+A ++ + + E
Sbjct: 2167 NKKDKEVQ-QLQENLDSTVTQLAAFTKS-MSSLQDDRDRVIDEAKKWERKFSDAIQSKEE 2224
Query: 709 EKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFLLESINGKSESPDH 768
E + C + DQ++ + + E+ + E Q E+ A + + + D
Sbjct: 2225 EIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQ---TEVQLQQKVCDT 2281
Query: 769 MVSQYQQALEEIERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSI 828
+ + ++ L ++E + + Q+ A+ +SE+ + QL D+ L+KC
Sbjct: 2282 LQGENKELLSQLEETRHLYHSSQNELAKL--------ESELKSLKDQLTDLSNSLEKCKE 2333
Query: 829 ERDQYKSEVELLEMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEESVNHMDGE 888
++ + + E + + E+L+T+++ + +S + E +N + +
Sbjct: 2334 QKGNLEGIIRQQEADIQNSKFSYEQLETDLQASR----------ELTSRLHEEINMKEQK 2383
Query: 889 SLKLRSLRVNVGQLLAMIVPDLDL-QQVNYDVDVVDEILGQVVEQ 932
+ L S G+ A+ V +L QQ + ++ ++ +L Q E+
Sbjct: 2384 IISLLS-----GKEEAIQVAIAELRQQHDKEIKELENLLSQEEEE 2423
Score = 34.7 bits (78), Expect = 0.43
Identities = 56/249 (22%), Positives = 101/249 (40%), Gaps = 37/249 (14%)
Query: 641 QTEVPSLVVKKEETVE---DEIDVRNDAVI--LPSCVEAEAKIHETQETTDKSADDAGCQ 695
+ ++ SL+ KEE ++ E+ ++D I L + + E + + E +K A D Q
Sbjct: 2381 EQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQ 2440
Query: 696 LQELRNQLLLVTEEKENY--KRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQST--ETD 751
L E L T +KEN K Q F + LQ + Y + E H S E D
Sbjct: 2441 LMET-----LKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKD 2495
Query: 752 AVFL-------------------LESINGKSESPDHMVSQYQQALEEIERLK--KQCSAL 790
+ ++ +N ++ D + QY++ L ++ +K +Q L
Sbjct: 2496 QLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLL 2555
Query: 791 QHVKAECSQCSNNESKSE--MDEMAVQLDDVFRQLDKCSIERDQYKSEVELLEMEKSQIR 848
+ + + N +K E + E +D+ R + E+ E+E L++ SQ+
Sbjct: 2556 EVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLT 2615
Query: 849 SQCEELKTE 857
Q L+ E
Sbjct: 2616 RQVTALQEE 2624
Score = 34.3 bits (77), Expect = 0.56
Identities = 71/435 (16%), Positives = 160/435 (36%), Gaps = 71/435 (16%)
Query: 533 QSEPESNSLKRRLSTRSSILNAKNRRLSSQFENSVYKGDDDDEDVIILEENSTPKPAVDH 592
+ E E +K +L + +++ +L+ + + E+ +++++ K
Sbjct: 141 EEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFIS 200
Query: 593 DIDMKSEQSHVEQGGVQVEFVGDSEPCGQTGSTSTSSSRCDQGNTAATQTEVPS---LVV 649
+ + Q+ EQ QV V + + +T A +TE+ ++
Sbjct: 201 TLQAQLSQTQAEQAAQQV--VREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQ 258
Query: 650 KKEETVEDEIDVRNDAVIL----------------PSCVEAEAKIHETQETTDKSADDAG 693
+K E E+ + R V L + EA+ + + T + +++
Sbjct: 259 RKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESK 318
Query: 694 CQLQELRNQLLLVTEEK---ENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTET 750
L+++ L V E K N + + H +Q + Q E+ +Y E H++
Sbjct: 319 ILLEKME---LEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEME 375
Query: 751 D-----------------AVFLLESINGK------------SESPDHMVSQYQQALEEIE 781
+ A L+ N K +++ + Q QQ +EI
Sbjct: 376 EKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEIS 435
Query: 782 RLKKQCSALQHVKA----------ECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSIERD 831
+ + QH A E +Q E+ + + + V+L++ L SIE +
Sbjct: 436 QFLNRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELE 495
Query: 832 QYKSEVELLEMEKSQIRSQ-----CEELKTEVEQLKSTNQQTATDVSTSSNIEESVNHMD 886
+ K+E E L + + + +Q + +E+ + N+++++ + ++ E+
Sbjct: 496 ELKAENEKLSSQITLLEAQNRTGEADREVSEISIVDIANKRSSSAEESGQDVLENTFSQK 555
Query: 887 GESLKLRSLRVNVGQ 901
+ L + L + Q
Sbjct: 556 HKELSVLLLEMKEAQ 570
Score = 33.9 bits (76), Expect = 0.73
Identities = 29/153 (18%), Positives = 64/153 (41%), Gaps = 4/153 (2%)
Query: 720 FTDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFLLESINGKSESPDHMVSQYQQALEE 779
+ QI L++RI + ++ K + Q+ E + LL I+ K D + Q+ + +
Sbjct: 1838 YLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTK----DGELKMLQEEVTK 1893
Query: 780 IERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEVEL 839
+ L +Q + + + E + + QL ++ + + + + EL
Sbjct: 1894 MNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNEL 1953
Query: 840 LEMEKSQIRSQCEELKTEVEQLKSTNQQTATDV 872
LE E ++ EL+ E +QL + +++
Sbjct: 1954 LESEMKNLKKCVSELEEEKQQLVKEKTKVESEI 1986
Score = 32.3 bits (72), Expect = 2.1
Identities = 49/248 (19%), Positives = 107/248 (43%), Gaps = 45/248 (18%)
Query: 629 SSRCDQGNTAATQ-----TEVPSLVVKKE---ETVEDEIDVRNDAVILPSCVEAEAKIHE 680
SS+ ++ + A +Q T++ L+++K+ ET++ I+ ++ V E + E
Sbjct: 858 SSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQV-----TEISFSMTE 912
Query: 681 TQETTDKSADDAGCQLQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMND--KY 738
++ G +++ L+ QL L++ +E K Q + L+Q EM+ +
Sbjct: 913 KMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQI 972
Query: 739 VKKETCHQSTETDAVFLLESINGKSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECS 798
K+E H+ LL+ N + + + Q AL + L ++ S L+
Sbjct: 973 SKEELQHEFD------LLKKENEQRKR------KLQAALINRKELLQRVSRLE------- 1013
Query: 799 QCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEVELLEMEKSQIRSQCEELKTEV 858
+E+A D+ +++ ER + + + E E + + S+C+E++ +
Sbjct: 1014 -----------EELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYL 1062
Query: 859 EQLKSTNQ 866
+Q S +
Sbjct: 1063 KQTISEKE 1070
Score = 32.0 bits (71), Expect = 2.8
Identities = 76/410 (18%), Positives = 162/410 (39%), Gaps = 56/410 (13%)
Query: 506 ESVPRRHLSEGTNSYATRLLNNHQVPPQSEPESNSLK---RRLSTRSSILNAKNRRLSSQ 562
+ + RHLS +L Q+ ++ E+N LK R L + LN++N +L ++
Sbjct: 2481 QQLEERHLSI--------ILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAE 2532
Query: 563 FENSVYKGDDDDEDVIILEENSTPKPAVDHDIDMKSEQSHVEQGGVQVEFVGDSEPCGQT 622
Y+ +D + +I ++S K ++ + E + + E + +SE +
Sbjct: 2533 LIQ--YR---EDLNQVITIKDSQQKQLLEVQLQQNKELEN--KYAKLEEKLKESEEANED 2585
Query: 623 GSTSTSSSRCDQGNTAATQTEVPSLVVKKEETVEDEIDVRNDAVILPSCVEAEAKIHETQ 682
S ++ + ++ + + E+ SL V + ++ + + A+ K+ E +
Sbjct: 2586 LRRSFNALQEEKQDLSK---EIESLKVSISQLTRQVTALQEEGTL--GLYHAQLKVKE-E 2639
Query: 683 ETTDKSADDAGCQ--LQELRNQLLLVTEE------------KENYKRQCH---MFTDQIK 725
E SA + Q + EL +L+ V +E K+ K H + ++ +
Sbjct: 2640 EVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETE 2699
Query: 726 VLQQRILEMNDKYVKKETCHQSTETDAVFLLESINGKSESPDHMVSQYQQALEEIERLKK 785
++R+ E+ V+ E + L I S + + A EE++ LK+
Sbjct: 2700 TAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKR 2759
Query: 786 QCSALQHVKAECSQCS--NNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEVELLEME 843
+ A A+ + N E + + E A ++ ++ + LE
Sbjct: 2760 KYDASLKELAQLKEQGLLNRERDALLSETAFSMNST-------------EENSLSHLEKL 2806
Query: 844 KSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEESVNHMDGESLKLR 893
Q+ S+ E+L QL+ + Q + ++++ +H+ E K R
Sbjct: 2807 NQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFR 2856
>gi|16262452 cingulin [Homo sapiens]
Length = 1203
Score = 52.8 bits (125), Expect = 2e-06
Identities = 47/261 (18%), Positives = 111/261 (42%), Gaps = 20/261 (7%)
Query: 628 SSSRCDQGNTAATQTEVPSLVVKKEETVEDEIDVRNDAVILPSCVEAEAKIHETQETTDK 687
S + G + Q E+ L + + + R D +L ++ + + E +
Sbjct: 899 SEAEKTSGGLSRLQDEIQRLRQALQASQAERDTARLDKELLAQRLQG---LEQEAENKKR 955
Query: 688 SADDAGCQLQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQS 747
S DD QL+ L ++ + E + K + TD++ + ++ ++ + +++ + Q
Sbjct: 956 SQDDRARQLKGLEEKVSRLETELDEEKNTVELLTDRVNRGRDQVDQLRTELMQERSARQD 1015
Query: 748 TETDAVFLLESINGKSESPDHMVSQYQQALEEIERLKKQCSALQ-HVKAE-----CSQCS 801
E D + LE N ++ +Q+ + +L+ Q LQ ++AE Q +
Sbjct: 1016 LECDKI-SLERQNKDLKTRLASSEGFQKPSASLSQLESQNQLLQERLQAEEREKTVLQST 1074
Query: 802 NNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEVELLEMEKSQIRSQCEELKTEVEQL 861
N + + ++ E+++Q++D ER + + L + ++ Q +E + E+E+L
Sbjct: 1075 NRKLERKVKELSIQIED----------ERQHVNDQKDQLSLRVKALKRQVDEAEEEIERL 1124
Query: 862 KSTNQQTATDVSTSSNIEESV 882
++ +V + E +
Sbjct: 1125 DGLRKKAQREVEEQHEVNEQL 1145
Score = 48.1 bits (113), Expect = 4e-05
Identities = 49/215 (22%), Positives = 97/215 (45%), Gaps = 24/215 (11%)
Query: 676 AKIHETQETTDKSADDAGCQLQELRNQLLLVTEEKENYKRQCHMFTDQIKV--------- 726
A++ + Q+T +++ ++ G Q + LR + E+K R +++
Sbjct: 810 ARLGQEQQTLNRALEEEGKQREVLRRGKAELEEQKRLLDRTVDRLNKELEKIGEDSKQAL 869
Query: 727 --LQQRILEMNDKYVKKETCHQSTETDAVFLLESINGKSESPDHMVSQYQQALE------ 778
LQ ++ + +K ++ Q D E +G + + +QAL+
Sbjct: 870 QQLQAQLEDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQALQASQAER 929
Query: 779 EIERLKKQCSA--LQHVKAECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSE 836
+ RL K+ A LQ ++ E + N+ +S+ D+ A QL + ++ + E D+ K+
Sbjct: 930 DTARLDKELLAQRLQGLEQE----AENKKRSQ-DDRARQLKGLEEKVSRLETELDEEKNT 984
Query: 837 VELLEMEKSQIRSQCEELKTEVEQLKSTNQQTATD 871
VELL ++ R Q ++L+TE+ Q +S Q D
Sbjct: 985 VELLTDRVNRGRDQVDQLRTELMQERSARQDLECD 1019
Score = 32.7 bits (73), Expect = 1.6
Identities = 43/206 (20%), Positives = 88/206 (42%), Gaps = 22/206 (10%)
Query: 695 QLQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTETDAV- 753
Q+ EL+N+L V + E K + + L + +LE + V+++ + E A+
Sbjct: 444 QVMELQNKLKHV-QGPEPAKEVLLKDLLETRELLEEVLEGKQR-VEEQLRLRERELTALK 501
Query: 754 -FLLESINGKSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECSQCSNNESKSEMDEM 812
L E + + + +H+ QYQ+ E++ R Q + H E +E +M
Sbjct: 502 GALKEEVASRDQEVEHVRQQYQRDTEQLRR-SMQDATQDHAVLE----------AERQKM 550
Query: 813 AVQLDDVFRQLDKCSIERDQY-------KSEVELLEMEKSQIRSQCEELKTEVEQLKSTN 865
+ + + R+L++ S E + K ++ + E Q+R + EE++ E+ +
Sbjct: 551 SALVRGLQRELEETSEETGHWQSMFQKNKEDLRATKQELLQLRMEKEEMEEELGEKIEVL 610
Query: 866 QQTATDVSTSSNIEESVNHMDGESLK 891
Q+ S+ V + E L+
Sbjct: 611 QRELEQARASAGDTRQVEVLKKELLR 636
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 52.8 bits (125), Expect = 2e-06
Identities = 57/274 (20%), Positives = 118/274 (43%), Gaps = 13/274 (4%)
Query: 596 MKSEQSHVEQGGVQVEFVGDSEPCGQTGSTSTSSSRCDQGNTAATQTEVPSLVVKKEETV 655
+K E + +++ + EF + Q T + Q A Q + ++ + E +
Sbjct: 864 LKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQ--LQAEQETLANVEEQCEWLI 921
Query: 656 EDEIDVRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQ----ELRNQLLLVTEEKE 711
+ +I + L VE E +I+ + +D +L+ +L L+ +EK
Sbjct: 922 KSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKR 981
Query: 712 NYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFLLESINGKSESP---DH 768
+ + T++++ L + I ++N + HQ T D E ++ S++ +
Sbjct: 982 TTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQ 1041
Query: 769 MVSQYQQALEEIERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSI 828
V + + ALE+ + + C H K E + N ES ++ L + +L K +
Sbjct: 1042 QVDELEGALEQERKARMNCERELH-KLEGNLKLNRESMENLESSQRHLAE---ELRKKEL 1097
Query: 829 ERDQYKSEVELLEMEKSQIRSQCEELKTEVEQLK 862
E Q S+VE + +Q++ +EL+T+++ LK
Sbjct: 1098 ELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLK 1131
Score = 40.8 bits (94), Expect = 0.006
Identities = 81/397 (20%), Positives = 155/397 (39%), Gaps = 64/397 (16%)
Query: 537 ESNSLKRRLSTRSSILNAKNRRLSSQFENSVYKGDDDDED-----VIILEENSTPKPAVD 591
E +K L S +NA+ + ++EN+V + +D ED I L+E + +
Sbjct: 1361 EEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVAN 1420
Query: 592 HDIDMKSEQSHVEQGGVQVEF-VGDSEPCGQTGSTSTSSSRCDQGNTAATQTEVPSLVVK 650
+ + +E+ Q++ +GD+ G ++++R DQ ++
Sbjct: 1421 ------ARNASLERARHQLQLELGDA--LSDLGKVRSAAARLDQKQ------------LQ 1460
Query: 651 KEETVEDEIDVRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQELRNQLLLVTEEK 710
+ + D ++ L + E + T+ K+ + QE + E
Sbjct: 1461 SGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQE------TLRREN 1514
Query: 711 ENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFLLESINGKSESPDHMV 770
+N + + T+Q++ + + EM + VKK + TE LE G E + +
Sbjct: 1515 KNLQEEISNLTNQVREGTKNLTEM--EKVKKLIEEEKTEVQVT--LEETEGALERNESKI 1570
Query: 771 SQYQQAL---------------EEIE--RLKKQC------SALQHVKAECSQCSNNESKS 807
+Q L EEIE R K+QC S+L + + + K
Sbjct: 1571 LHFQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKM 1630
Query: 808 EMD--EMAVQLDDVFRQLDKCSIERDQYKSEVELLEM---EKSQIRSQCEELKTEVEQLK 862
E D EM +QL RQ+ + + Q + +++ L+M + +Q+ S +E E+
Sbjct: 1631 EEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRN 1690
Query: 863 STNQQTATDVSTSSNIEESVNHMDGESLKLRSLRVNV 899
S Q D+ + E + E L + R+N+
Sbjct: 1691 SLLQSELEDLRSLQEQTERGRRLSEEELLEATERINL 1727
Score = 40.0 bits (92), Expect = 0.010
Identities = 38/190 (20%), Positives = 85/190 (44%), Gaps = 8/190 (4%)
Query: 673 EAEAKIHETQETTDKSADDAGCQLQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRIL 732
EAE + E Q +K A A + L +L + + +R I LQ+R+
Sbjct: 1752 EAEEVVQECQNAEEK-AKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLA 1810
Query: 733 EMNDKYVKKETCHQSTETDAVFLLESINGKSESPDHMVSQYQQALEEIERLKKQCSALQH 792
E + V LE G+ E ++ Q+ +ER K+ +
Sbjct: 1811 EAEQMALMGSRKQIQKLESRVRELE---GELEGEIRRSAEAQRGARRLERCIKELT---- 1863
Query: 793 VKAECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEVELLEMEKSQIRSQCE 852
+AE + + + +++MD++ +++ + +Q++ + +QY S+ + + E ++++ + E
Sbjct: 1864 YQAEEDKKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAE 1923
Query: 853 ELKTEVEQLK 862
+++V +LK
Sbjct: 1924 VAESQVNKLK 1933
Score = 38.5 bits (88), Expect = 0.030
Identities = 69/348 (19%), Positives = 136/348 (39%), Gaps = 42/348 (12%)
Query: 533 QSEPESNSLKRRLSTRSSI---LNAKNRRLSSQ-FENSVYKGDDDDEDVIILEENSTPKP 588
Q E L R+ I L A+ R+L + FE + K DD E +++ E K
Sbjct: 926 QLEARVKELSERVEEEEEINSELTARGRKLEDECFE--LKKEIDDLETMLVKSEKE--KR 981
Query: 589 AVDHDIDMKSEQSHVEQGGVQVEFVGDSEPCGQTGSTSTSSSRCDQGNTAATQTEVPSLV 648
+H + +E+ VEF+ + + + + + E S +
Sbjct: 982 TTEHKVKNLTEE---------VEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSL 1032
Query: 649 VKKEETVEDEIDVRNDAVILP--SCVEAEAKIH----------ETQETTDKSADDAGCQL 696
K +E ++D A+ + + E ++H E+ E + S +L
Sbjct: 1033 SKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEEL 1092
Query: 697 QELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFLL 756
++ +L + + EN K +K LQ +I ++ +K + T E + L
Sbjct: 1093 RKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLT 1152
Query: 757 ESINGKSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECSQCS---NNESKSEMDEMA 813
+ + +E + + +L ++E KKQ + Q + + + + S S A
Sbjct: 1153 QDLADLNERLEEVGGS---SLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHA 1209
Query: 814 VQLDDVFRQLDKCSIERDQYKSEVELLEMEKSQIRSQCEELKTEVEQL 861
L ++ Q++ Q K + LE +KS ++ + ++L T VEQ+
Sbjct: 1210 DSLAELEGQVENLQ----QVKQK---LEKDKSDLQLEVDDLLTRVEQM 1250
Score = 37.4 bits (85), Expect = 0.066
Identities = 60/304 (19%), Positives = 121/304 (39%), Gaps = 42/304 (13%)
Query: 648 VVKKEETVEDEIDVRNDAVILPSCVEA------EAKIHETQETTDKSADDAGCQLQELRN 701
+VK E E+ ++ + L +E E K + T +K+ D QLQ +
Sbjct: 851 LVKSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKN--DLILQLQAEQE 908
Query: 702 QLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFL------ 755
L V E+ E + ++K L +R+ E + + + E + L
Sbjct: 909 TLANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDD 968
Query: 756 LESINGKSESPDHMVSQYQQAL-EEIERLKKQCSALQHVKAECSQCSNNESKSEMDEMAV 814
LE++ KSE + L EE+E L + S L ++ + +D++ +
Sbjct: 969 LETMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRA----AKVVQEAHQQTLDDLHM 1024
Query: 815 QLDDVFRQLDKCSIERDQYKSEVELLEMEKSQIRSQCEELKTEVEQLKSTNQQTATDVST 874
+ ++ L K +++ +Q E+E ++ + R CE ++E N++ +
Sbjct: 1025 E-EEKLSSLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRE------S 1077
Query: 875 SSNIEESVNHMDGESLKLRSLRVNVGQLLAMIVPDLDLQQVNYDVDVVDEILGQVVEQMS 934
N+E S H+ E K +L+L Q+N V+ ++ Q+ + +
Sbjct: 1078 MENLESSQRHLAEELRK----------------KELELSQMNSKVENEKGLVAQLQKTVK 1121
Query: 935 EISS 938
E+ +
Sbjct: 1122 ELQT 1125
>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
Length = 1979
Score = 52.0 bits (123), Expect = 3e-06
Identities = 54/235 (22%), Positives = 101/235 (42%), Gaps = 54/235 (22%)
Query: 685 TDKSADDAGCQLQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETC 744
TD S C+LQ + + E K+N ++ ++ VLQ
Sbjct: 203 TDNSDQSEICKLQNI------IKELKQNRSQEIDDHQHEMSVLQN--------------A 242
Query: 745 HQSTETDAVFLLESINGKSESPDHMVSQYQQALEEIERLKKQ---------CSALQHVKA 795
HQ T+ S +S Y++ +EE+E L +Q S + ++
Sbjct: 243 HQQKLTEI----------SRRHREELSDYEERIEELENLLQQGGSGVIETDLSKIYEMQK 292
Query: 796 --ECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEVELLEMEKSQIRSQCEE 853
+ Q ES +M+++ ++ D+ ++L +RD + E E L +EK QI +CE
Sbjct: 293 TIQVLQIEKVESTKKMEQLEDKIKDINKKLSSAENDRDILRREQEQLNVEKRQIMEECEN 352
Query: 854 LKTEVEQLKST---NQQTATD----VSTSSNIEE------SVNHMDGESLKLRSL 895
LK E +L+ + T T+ ++ S+++EE +++ + E ++L SL
Sbjct: 353 LKLECSKLQPSAVKQSDTMTEKERILAQSASVEEVFRLQQALSDAENEIMRLSSL 407
Score = 46.2 bits (108), Expect = 1e-04
Identities = 77/369 (20%), Positives = 148/369 (40%), Gaps = 62/369 (16%)
Query: 588 PAVDHDIDMK-----SEQSHVEQGGVQVEF----VGDSEPCGQTGSTSTSSSRCDQGNTA 638
P+ HD DM S Q + + +V VG QT S + + DQ
Sbjct: 154 PSAFHDDDMDFGDIISSQQEINRLSNEVSRLESEVGHWRHIAQT-SKAQGTDNSDQSEIC 212
Query: 639 ATQTEVPSLVVKKEETVEDEIDVRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQE 698
Q + L + + ++D +++ +L + + K+ E + D +++E
Sbjct: 213 KLQNIIKELKQNRSQEIDDH---QHEMSVLQNA--HQQKLTEISRRHREELSDYEERIEE 267
Query: 699 LRNQL------LLVTEEKENYKRQCHMFTDQIKVLQ--QRILEMNDKYVKKETCHQSTET 750
L N L ++ T+ + Y+ Q + QI+ ++ +++ ++ DK S E
Sbjct: 268 LENLLQQGGSGVIETDLSKIYEMQKTIQVLQIEKVESTKKMEQLEDKIKDINKKLSSAEN 327
Query: 751 DAVFLLESINGKSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECSQCSNNESKSEMD 810
D L + + + +Q +EE E LK +CS LQ + Q K +
Sbjct: 328 DRDIL-------RREQEQLNVEKRQIMEECENLKLECSKLQ--PSAVKQSDTMTEKERIL 378
Query: 811 EMAVQLDDVFRQ-----------LDKCSIERD--------QYKSEVELLEMEKSQIRSQC 851
+ +++VFR + S+ +D + K +E+LE EKS + +
Sbjct: 379 AQSASVEEVFRLQQALSDAENEIMRLSSLNQDNSLAEDNLKLKMRIEVLEKEKSLLSQEK 438
Query: 852 EELK-------TEVEQLKSTNQQTATDVSTSSNIEESVNHMDGESLKLRSLRVNVGQLLA 904
EEL+ E E +KST D+S S + + +++ + +L ++ + L
Sbjct: 439 EELQMSLLKLNNEYEVIKST---ATRDISLDSELHDLRLNLEAKEQELNQ-SISEKETLI 494
Query: 905 MIVPDLDLQ 913
+ +LD Q
Sbjct: 495 AEIEELDRQ 503
Score = 44.7 bits (104), Expect = 4e-04
Identities = 73/377 (19%), Positives = 163/377 (43%), Gaps = 32/377 (8%)
Query: 529 QVPPQSEPESNSL--KRRLSTRSSILNAKNR--RLSSQFENSVYKGDDDDEDVIILEENS 584
++ P + +S+++ K R+ +S+ + R + S EN + + ++D + E+N
Sbjct: 359 KLQPSAVKQSDTMTEKERILAQSASVEEVFRLQQALSDAENEIMRLSSLNQDNSLAEDNL 418
Query: 585 TPKPAVDHDIDMKSEQSHVEQGGVQVEFVGDSEPCGQTGSTSTSSSRCDQG------NTA 638
K ++ KS S E+ +Q+ + + ST+T D N
Sbjct: 419 KLKMRIEVLEKEKSLLSQ-EKEELQMSLLKLNNEYEVIKSTATRDISLDSELHDLRLNLE 477
Query: 639 ATQTEVPSLVVKKEETVED--EIDVRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQL 696
A + E+ + +KE + + E+D +N + + ++ + Q D L
Sbjct: 478 AKEQELNQSISEKETLIAEIEELDRQNQEAT-KHMILIKDQLSKQQNEGDSIISKLKQDL 536
Query: 697 QELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFLL 756
+ + ++ + ++K + ++ + Q + L Q + +ND ++ K+ E L+
Sbjct: 537 NDEKKRVHQLEDDKMDITKELDV---QKEKLIQSEVALNDLHLTKQKLEDKVEN----LV 589
Query: 757 ESINGKSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECSQCSNNESKSEM-DEMAVQ 815
+ +N ES VS ++ LE E +++ L ++ E Q N +S S D + +
Sbjct: 590 DQLNKSQESN---VSIQKENLELKEHIRQNEEELSRIRNELMQSLNQDSNSNFKDTLLKE 646
Query: 816 LDDVFRQLDKCSIERDQYKSEVELL----EMEKSQIRSQCEELKTEVEQLKSTNQQTATD 871
+ R L + E +Q ++ + +ME ++ CE+++ ++E+ + N Q + +
Sbjct: 647 REAEVRNLKQNLSELEQLNENLKKVAFDVKMENEKLVLACEDVRHQLEECLAGNNQLSLE 706
Query: 872 VSTSSNIEESVNHMDGE 888
+T I E++ GE
Sbjct: 707 KNT---IVETLKMEKGE 720
Score = 42.4 bits (98), Expect = 0.002
Identities = 58/275 (21%), Positives = 111/275 (40%), Gaps = 30/275 (10%)
Query: 634 QGNTAATQTEVPSLVVKKEETVEDEIDVRNDAVILPSCVEAEAKIHETQETT---DKSAD 690
QG + +T++ S + + ++T++ V+ VE+ K+ + ++ +K
Sbjct: 274 QGGSGVIETDL-SKIYEMQKTIQ---------VLQIEKVESTKKMEQLEDKIKDINKKLS 323
Query: 691 DAGCQLQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETC-HQSTE 749
A LR + + EK +C + LQ ++ +D +KE QS
Sbjct: 324 SAENDRDILRREQEQLNVEKRQIMEECENLKLECSKLQPSAVKQSDTMTEKERILAQSAS 383
Query: 750 TDAVFLLESINGKSESPDHMVSQYQQ---ALEEIERLKKQCSALQHVKAECSQCSNNESK 806
+ VF L+ +E+ +S Q E+ +LK + L+ K+ SQ K
Sbjct: 384 VEEVFRLQQALSDAENEIMRLSSLNQDNSLAEDNLKLKMRIEVLEKEKSLLSQ-----EK 438
Query: 807 SEMDEMAVQLDDVFRQLDKCSIERDQYKSEV-------ELLEMEKSQIRSQCEELKTEVE 859
E+ ++L++ + + + SE+ E E E +Q S+ E L E+E
Sbjct: 439 EELQMSLLKLNNEYEVIKSTATRDISLDSELHDLRLNLEAKEQELNQSISEKETLIAEIE 498
Query: 860 QLKSTNQQ-TATDVSTSSNIEESVNHMDGESLKLR 893
+L NQ+ T + + + N D KL+
Sbjct: 499 ELDRQNQEATKHMILIKDQLSKQQNEGDSIISKLK 533
Score = 40.0 bits (92), Expect = 0.010
Identities = 50/244 (20%), Positives = 102/244 (41%), Gaps = 16/244 (6%)
Query: 633 DQGNTAATQTEVPSLVVKKEETVEDEIDVRNDAVILP---SCVEAEAKIHETQETTDKSA 689
+QG T + ++ +E+TV + + D V+L +E A +E Q DK
Sbjct: 1518 EQGKTGELNQLLNAVKSMQEKTVVFQQE--RDQVMLALKQKQMENTALQNEVQRLRDKEF 1575
Query: 690 DDAGCQLQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTE 749
+ +L+ LRN LL E +++Y R+ D+ L++++ + +K V ++
Sbjct: 1576 R-SNQELERLRNHLL---ESEDSYTREALAAEDREAKLRKKVTVLEEKLVSSSNAMENAS 1631
Query: 750 TDAVFLLES----INGKSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECSQCSNNES 805
A +ES +N S+ D Q + E++++ + LQ V Q
Sbjct: 1632 HQASVQVESLQEQLNVVSKQRDETALQLSVSQEQVKQYALSLANLQMVLEHFQQEEKAMY 1691
Query: 806 KSEMD---EMAVQLDDVFRQLDKCSIERDQYKSEVELLEMEKSQIRSQCEELKTEVEQLK 862
+E++ ++ + L+ I + E S++ Q + + ++E+LK
Sbjct: 1692 SAELEKQKQLIAEWKKNAENLEGKVISLQECLDEANAALDSASRLTEQLDVKEEQIEELK 1751
Query: 863 STNQ 866
N+
Sbjct: 1752 RQNE 1755
Score = 34.3 bits (77), Expect = 0.56
Identities = 76/440 (17%), Positives = 175/440 (39%), Gaps = 100/440 (22%)
Query: 537 ESNSLKR---RLSTRSSILNAKNRRLSSQFEN---SVYKGDDDDEDVIILEENSTPKPAV 590
+ NSL +L R +L + LS + E S+ K +++ E +++ +T ++
Sbjct: 409 QDNSLAEDNLKLKMRIEVLEKEKSLLSQEKEELQMSLLKLNNEYE---VIKSTATRDISL 465
Query: 591 D---HDI--DMKSEQSHVEQGGVQVE-FVGDSEPCGQTGSTSTSSSRCDQGNTAATQTEV 644
D HD+ ++++++ + Q + E + + E + +T + + Q E
Sbjct: 466 DSELHDLRLNLEAKEQELNQSISEKETLIAEIEELDRQNQEATKHMILIKDQLSKQQNEG 525
Query: 645 PSLVVKKEETVEDEIDVRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQELRNQLL 704
S++ K ++ + DE + ++H+ ++ + Q ++L +
Sbjct: 526 DSIISKLKQDLNDE----------------KKRVHQLEDDKMDITKELDVQKEKLIQSEV 569
Query: 705 LVTE---EKENYKRQCHMFTDQIKVLQQRILEMNDKYVK-KETCHQSTETDAVF---LLE 757
+ + K+ + + DQ+ Q+ + + + ++ KE Q+ E + L++
Sbjct: 570 ALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQ 629
Query: 758 SINGKSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQLD 817
S+N S S + + ++ E+ LK+ S L+ + + + + K E +++ + +
Sbjct: 630 SLNQDSNS-NFKDTLLKEREAEVRNLKQNLSELEQLNENLKKVAF-DVKMENEKLVLACE 687
Query: 818 DVFRQLDKCSIERDQYKSE----VELLEMEKSQIRSQC---------------------- 851
DV QL++C +Q E VE L+MEK +I ++
Sbjct: 688 DVRHQLEECLAGNNQLSLEKNTIVETLKMEKGEIEAELCWAKKRLLEEANKYEKTIEELS 747
Query: 852 ----------------------------EELKTEVEQLKSTNQQTATDVSTSSNIEESVN 883
ELK +EQ+ + +++T +S+S ++ +
Sbjct: 748 NARNLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMDTDHKETKDVLSSSLEEQKQLT 807
Query: 884 HMDG------ESLKLRSLRV 897
+ E LK RS ++
Sbjct: 808 QLINKKEIFIEKLKERSSKL 827
Score = 32.3 bits (72), Expect = 2.1
Identities = 47/276 (17%), Positives = 107/276 (38%), Gaps = 38/276 (13%)
Query: 641 QTEVPSLVVKKEETVE----------DEIDVRNDAVILPSCVEAEAKIHETQETTDKSAD 690
Q ++ L+ KKE +E +E+D + A+ + +T E D+S
Sbjct: 803 QKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQAL------RKNEILRQTIEEKDRSLG 856
Query: 691 DAGCQLQELRNQLLLVTEEKENYKRQCHMFT-DQIKVLQQRILEMND--KYVKKETCH-- 745
+ L+ +L + EE+ T D + L + ++N +++++E H
Sbjct: 857 SMKEENNHLQEELERLREEQSRTAPVADPKTLDSVTELASEVSQLNTIKEHLEEEIKHHQ 916
Query: 746 ---QSTETDAVFLLESINGKSESPDHMVSQYQQA--------LEEIERLKKQCSALQHVK 794
+ + LL+S+ + + D Q++Q LE+ E +K ++ +K
Sbjct: 917 KIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNATHTQLFLEKDEEIKSLQKTIEQIK 976
Query: 795 AECS------QCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEVELLEMEKSQIR 848
+ Q N++ E ++ +++ + D E ++ ++ E+E +
Sbjct: 977 TQLHEERQDIQTDNSDIFQETKVQSLNIENGSEKHDLSKAETERLVKGIKERELEIKLLN 1036
Query: 849 SQCEELKTEVEQLKSTNQQTATDVSTSSNIEESVNH 884
+ L +++QL T + ++E H
Sbjct: 1037 EKNISLTKQIDQLSKDEVGKLTQIIQQKDLEIQALH 1072
>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
Length = 1460
Score = 51.6 bits (122), Expect = 3e-06
Identities = 97/485 (20%), Positives = 187/485 (38%), Gaps = 62/485 (12%)
Query: 447 EVPEEPEDEDLVHPTYEKTYKKTNKEKFRIRQPEMIPRINA-ELLFRPTALSTPSFSSPK 505
E E+PE++ V PT P + P + + E + P LS + + +
Sbjct: 554 EEAEDPEEKVAVSPT-----------------PPVSPEVRSTEPVAPPEQLSEAALKAME 596
Query: 506 ESVPR------RHLSEGTNSYATRL------------LNNHQVPPQSEPESNSLKRRLST 547
E+V + RHL E +L L HQ Q E +SL+ RL
Sbjct: 597 EAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQ---QKEQSLSSLRERLQK 653
Query: 548 RSSILNAKNRRLSSQ----FENSVYKGDDDDEDVIILE-ENSTPKPAVDHDIDMKSEQSH 602
A+ R SQ V DED I E E S K + + K+E++
Sbjct: 654 AIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERAS 713
Query: 603 VEQGGVQVEFVGDSEPCGQTGSTSTSSSRCDQGNTAATQTEVPSLVVKKEETVEDEIDVR 662
+EQ Q+ E S + + + A Q L +++E V ++
Sbjct: 714 LEQKNRQMLEQLKEEI---EASEKSEQAALNAAKEKALQQLREQLEGERKEAVAT-LEKE 769
Query: 663 NDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQELRNQLLLVTEEKENYKRQCHMFT- 721
+ A + C EAK E + K +A Q +E + Q L E +++ H+
Sbjct: 770 HSAELERLCSSLEAKHREVVSSLQKKIQEAQ-QKEEAQLQKCLGQVEHRVHQKSYHVAGY 828
Query: 722 --DQIKVLQQRILEMNDKY------VKKETCHQSTETDAVFLLESINGKSESPDHMVSQY 773
+ +L+++ E+ ++ +K+E + + E ++E H+ +
Sbjct: 829 EHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGEL 888
Query: 774 QQALEEIERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQLD----DVFRQLDKCSIE 829
++ ER + QH + E + + E + ++ ++ + L+ DV +L ++
Sbjct: 889 ERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQ 948
Query: 830 RDQYKSEVELLEMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEESVNHMDGES 889
+ + E + L + Q+ + EE +QL+ ++ + ++ + E ++ +
Sbjct: 949 EETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARK 1008
Query: 890 LKLRS 894
LKL S
Sbjct: 1009 LKLES 1013
Score = 34.3 bits (77), Expect = 0.56
Identities = 53/266 (19%), Positives = 114/266 (42%), Gaps = 40/266 (15%)
Query: 636 NTAATQTEVPSLVVKKEETVEDEIDVRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQ 695
+ A + E+ SL+ +K + VE E + R D + E Q+ K+ + +
Sbjct: 824 HVAGYEHELSSLLREKRQEVEGEHERRLDKMK-----------EEHQQVMAKAREQYEAE 872
Query: 696 LQELRNQLL-LVTEEKENYKRQCHMFTDQIKVLQQRILE-MNDKYVKKETCHQSTETDAV 753
++ R +LL +T E E +R + ++ Q + LE + ++ ++E Q E D
Sbjct: 873 ERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLE 932
Query: 754 FLLESINGKS---ESPDHMVSQYQQALEEIER---LKKQCSALQHVKAECSQC------- 800
+ + + E + + +Q L +++R LK + + H + E +Q
Sbjct: 933 TRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQ 992
Query: 801 SNNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEVELLEMEKSQIRSQCEELKTEVEQ 860
SN + + +DE+ Q K +E S+V+LL+ + Q++ L+ E ++
Sbjct: 993 SNQQLREILDEL---------QARKLKLE-----SQVDLLQAQSQQLQKHFSSLEAEAQK 1038
Query: 861 LKSTNQQTATDVSTSSNIEESVNHMD 886
+ ++ + + +S E H++
Sbjct: 1039 KQHLLREVTVEENNASPHFEPDLHIE 1064
>gi|56550043 sarcolemma associated protein [Homo sapiens]
Length = 811
Score = 51.6 bits (122), Expect = 3e-06
Identities = 78/381 (20%), Positives = 164/381 (43%), Gaps = 58/381 (15%)
Query: 542 KRRLSTRSSILNAKNRRLSSQFENSVYKGDDDDEDVIILEENSTPKPAVD----HDIDMK 597
K+ L + + K + L ++ E D +E + L+E+ K D H ++
Sbjct: 339 KKELQHKIDEMEEKEQELQAKIEALQADNDFTNERLTALQEHLLSKSGGDCTFIHQF-IE 397
Query: 598 SEQSHVEQGGVQVEFVGDSEPCGQTGSTSTSSSRCDQGNTAATQTEVPSLVVKKEETVED 657
++ + +G + ++ +T + + +R + + + T + PS ++T +
Sbjct: 398 CQKKLIVEGHL-------TKAVEETKLSKENQTRAKESDFSDTLS--PSKEKSSDDTTDA 448
Query: 658 EID-------------VRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQELRNQLL 704
++D +++D S +EA+ +I ++ ++ + A Q+
Sbjct: 449 QMDEQDLNEPLAKVSLLKDDLQGAQSEIEAKQEIQHLRKELIEAQELARTSKQKCFELQA 508
Query: 705 LVTEEKENYKRQCHMFTDQIKVLQQRI--LEMNDKYVKKETCHQSTET--------DAVF 754
L+ EE++ Y+ Q T QI+VLQ ++ L ++ + +++E + T T D +
Sbjct: 509 LLEEERKAYRNQVEESTKQIQVLQAQLQRLHIDTENLREEKDSEITSTRDELLSARDEIL 568
Query: 755 LLESINGKSESP-DHMVSQYQQALEEIERLKKQCSALQHVKAECSQCSNNESKSEMDEMA 813
LL K S D ++ Q E LKK V+AE + ++ SE ++
Sbjct: 569 LLHQAAAKVASERDTDIASLQ------EELKK-------VRAELERW--RKAASEYEKEI 613
Query: 814 VQLDDVFRQLDKCSIERDQYKSEVELLEMEKSQIRSQCEELKTEVEQLKSTNQQTATDVS 873
L + F+ +C DQ + E L+ E ++R + L+TE LK N ++++
Sbjct: 614 TSLQNSFQL--RCQQCEDQQREEATRLQGELEKLRKEWNALETECHSLKRENVLLSSELQ 671
Query: 874 TSSNIEESVNHMDGESLKLRS 894
E+ +++ +SL+L S
Sbjct: 672 RQ---EKELHNSQKQSLELTS 689
Score = 38.5 bits (88), Expect = 0.030
Identities = 29/136 (21%), Positives = 60/136 (44%), Gaps = 6/136 (4%)
Query: 699 LRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFLLES 758
LR +L+ + E+K NY+ + ++ + Q +E+ K + E +TE + L E
Sbjct: 236 LRKELIALQEDKHNYETTA---KESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEM 292
Query: 759 INGKSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECSQCSNNESKS---EMDEMAVQ 815
E + ++Y A+ EI+ L + + + E Q E K ++DEM +
Sbjct: 293 NERTQEELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGQAEKKELQHKIDEMEEK 352
Query: 816 LDDVFRQLDKCSIERD 831
++ +++ + D
Sbjct: 353 EQELQAKIEALQADND 368
Score = 37.4 bits (85), Expect = 0.066
Identities = 30/129 (23%), Positives = 64/129 (49%), Gaps = 7/129 (5%)
Query: 770 VSQY-QQALEEIERLKKQCSALQHVKAECSQCSNNESKSEMDE--MAVQLDDVFRQLDKC 826
+SQY Q+AL + L+++ + LQ + A + S+ ++ +DE + +L+ + QL C
Sbjct: 168 LSQYLQEALHREQMLEQKLATLQRLLAITQEASDTSWQALIDEDRLLSRLEVMGNQLQAC 227
Query: 827 SIERDQYKSEVELLEMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEESVNHMD 886
S + + EL+ +++ + + T E L+ Q+ V S +E S+++ +
Sbjct: 228 SKNQTEDSLRKELIALQEDKHNYE----TTAKESLRRVLQEKIEVVRKLSEVERSLSNTE 283
Query: 887 GESLKLRSL 895
E L+ +
Sbjct: 284 DECTHLKEM 292
>gi|4502443 dystonin isoform 1e precursor [Homo sapiens]
Length = 2649
Score = 51.2 bits (121), Expect = 4e-06
Identities = 50/235 (21%), Positives = 105/235 (44%), Gaps = 27/235 (11%)
Query: 673 EAEAKIHETQETTDKSADDAGCQLQELRN---QLLLVTEEKENYKRQCHMFTDQIKVLQQ 729
E ++++T +++ +A + RN +L + EK +R+ T V ++
Sbjct: 1440 ELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQREVDRITRAHAVAEK 1499
Query: 730 RILEMNDKYVKKETCHQSTETDAVFLLESINGKSESPDHMVSQYQ----QALEEIERLKK 785
I +N + H + + L+ KS DH+ Q++ Q L+ I+ K+
Sbjct: 1500 NIQHLNSQI------HSFRDEKELERLQICQRKS---DHLKEQFEKSHEQLLQNIKAEKE 1550
Query: 786 QCSALQHVKAECSQCSNNESKSEMDEMAVQ-LDDVFRQLDKCSIERDQYKSEVELLEMEK 844
+Q + E E +E EM Q ++++ RQ ++ + + ++E E + +EK
Sbjct: 1551 NNDKIQRLNEEL------EKSNECAEMLKQKVEELTRQNNETKLMMQRIQAESENIVLEK 1604
Query: 845 SQIRSQCEELKTEV----EQLKSTNQQTATDVSTSSNIEESVNHMDGESLKLRSL 895
I+ +CE LK + +QL+STN+ T + + + ++ + K ++L
Sbjct: 1605 QTIQQRCEALKIQADGFKDQLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQNL 1659
Score = 31.2 bits (69), Expect = 4.7
Identities = 55/302 (18%), Positives = 117/302 (38%), Gaps = 49/302 (16%)
Query: 641 QTEVPSLVVKKEETVEDEI--DVRN--DAVILPSCVEAEAKIHETQ-ETTDKSADDAGCQ 695
++ V + K E E+E+ RN D + E+EAK + + ET + + A +
Sbjct: 1154 KSRVEEELPKVREAAENELRKQQRNVEDISLQKIRAESEAKQYRRELETIVREKEAAERE 1213
Query: 696 LQELRNQLLLVTEEKENYKRQCHMFTDQIK--VLQQRILEMNDKYVKKETCHQSTETDAV 753
L+ +R + ++ + F +Q++ +R LE D +K+ E
Sbjct: 1214 LERVRQLTIEAEAKRAAVEENLLNFRNQLEENTFTRRTLE--DHLKRKDLSLNDLEQQKN 1271
Query: 754 FLLESINGKSESPDHMVSQYQQALEEIERLK----KQCSALQHVKAECSQ--------CS 801
L+E + K ++ + ++ +Q +++ K KQ Q ++ E + C
Sbjct: 1272 KLMEELRRKRDNEEELLKLIKQMEKDLAFQKQVAEKQLKEKQKIELEARRKITEIQYTCR 1331
Query: 802 NN----------------------ESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEVEL 839
N K + +E+ Q+D++ K + + E+
Sbjct: 1332 ENALPVCPITQATSCRAVTGLQQEHDKQKAEELKQQVDELTAANRKAEQDMRELTYELNA 1391
Query: 840 LEMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEESVNHMDGESLKLRSLRVNV 899
L++EK+ + LK ++++ +T + ++ E+ G S +LR L +
Sbjct: 1392 LQLEKTSSEEKARLLKDKLDETNNTLRCLKLELERKDQAEK------GYSQQLRELGRQL 1445
Query: 900 GQ 901
Q
Sbjct: 1446 NQ 1447
>gi|34577114 cytomatrix protein p110 [Homo sapiens]
Length = 957
Score = 50.8 bits (120), Expect = 6e-06
Identities = 86/431 (19%), Positives = 177/431 (41%), Gaps = 74/431 (17%)
Query: 565 NSVYKGDDDDEDVIILEENSTPKPAVDHDID-MKSEQSHVEQGGVQVE-----FVGDSEP 618
N V +D +E++ +E + + ID +K E S E + ++ +
Sbjct: 407 NGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSD 466
Query: 619 CGQTGSTSTSSSRCDQGNTAATQTEVPSLVVKKEETVEDEIDVRNDAVILPSCVEAEAKI 678
C Q S + A QTEV +L ++ EE K
Sbjct: 467 CKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESF----------------LNKKT 510
Query: 679 HETQETTDKSADDAGCQLQELRNQLLLVTEEKENY-KRQCHMFTDQIKVLQQRILEMNDK 737
+ Q+ T++ AG +++++++ +L V E K N +++ +Q++ +++ + D+
Sbjct: 511 KQLQDLTEEKGTLAG-EIRDMKD-MLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDR 568
Query: 738 YVKKETCHQSTETDAVFLLESINGKSESPDHMVSQYQ----QALEEIER-------LKKQ 786
+T +T+T L E+++ K + + Q + + LEEIE LK++
Sbjct: 569 VKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEK 628
Query: 787 CSALQ---------------HVKAECSQCSNNESKSEMDEMAVQ-----LDDVFRQLDKC 826
+ALQ H + S +SK + E+A++ + QL K
Sbjct: 629 VNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKA 688
Query: 827 -SIERD-----QYKSEVELLEMEKSQIRSQCEELKTEVEQL-----KSTNQQTATDVSTS 875
+IE D ++ +++ L+ E S R +C + + EV++L + N++ D +
Sbjct: 689 HNIEDDSRMNPEFADQIKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIA 748
Query: 876 SNIEESVNHMDGESLKLRSLRVNV-------GQLLAMIVPDLDLQQVNYDVDVVDEILGQ 928
++ HM ++ K+ +L+ N QLL + D N ++E++
Sbjct: 749 ELESLTLRHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMADNSQHLQIEELMNA 808
Query: 929 VVEQMSEISST 939
+ + E+ +T
Sbjct: 809 LEKTRQELDAT 819
Score = 47.8 bits (112), Expect = 5e-05
Identities = 59/301 (19%), Positives = 141/301 (46%), Gaps = 31/301 (10%)
Query: 638 AATQTEVPSLVV----KKEETVE--DEIDVRNDAVILPSCVEAEAKIHETQETT----DK 687
A +++V L V K++E + +E+ R+ P+ +A + E ++T ++
Sbjct: 333 AEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDTKIASLER 392
Query: 688 SADDAGCQLQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQS 747
+ D ++Q L+ +L TE++E +Q ++ K ++ +I ++ + KKE+ +
Sbjct: 393 NIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLA 452
Query: 748 TETDAVFLLESINGKSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECSQCSNNESKS 807
+T LE+++ ++ Q+ + L+E K+Q +A+ + + + E +S
Sbjct: 453 LQTK----LETLSNQNSD----CKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKES 504
Query: 808 EMDEMAVQLDDVFRQLDKCSIERDQYKSEVELLEMEKSQIRSQCEELKTEVEQLKSTNQQ 867
+++ QL D+ + + E K +E+ E + + ++ + E L+ EQL+ ++Q
Sbjct: 505 FLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQ---EQLRDKDKQ 561
Query: 868 TATDVSTSSNIEESVNHMDGESLKLRSLRVNVGQLLA---MIVPDLDLQQVNYDVDVVDE 924
+N+++ V + +S + + + L+ I+ L Q+ D + ++E
Sbjct: 562 L-------TNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEE 614
Query: 925 I 925
I
Sbjct: 615 I 615
>gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens]
Length = 898
Score = 50.4 bits (119), Expect = 8e-06
Identities = 63/336 (18%), Positives = 144/336 (42%), Gaps = 18/336 (5%)
Query: 533 QSEPESNSLKRRLSTRSSILNAKNRRLSSQFENSVYKGDDDDEDVIILEENSTPKPAVDH 592
+ E ES L++ T L N+ L + + E +
Sbjct: 317 RGEKESLDLRKEKETLEKKLRDANKELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIR 376
Query: 593 DIDMKSEQ--SHVEQGGVQVEFVGDSEPCGQTGSTSTSSSRCDQGNTAATQTEVPSLVVK 650
+ID E SHV ++V++ ++ + S + + + T TQ + + ++
Sbjct: 377 EIDKLKEDINSHV----IKVKWA-QNKLKAEMDSHKETKDKLKETTTKLTQAKEEADQIR 431
Query: 651 KEETVEDEIDVRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQELRNQLLLVTEEK 710
K +D I ++ + S E +AK+ T+ +K + QL+ ++ +E
Sbjct: 432 KN--CQDMIKTYQESEEIKSN-ELDAKLRVTKGELEKQMQEKSDQLEMHHAKI----KEL 484
Query: 711 ENYKRQCHMFTDQIKVLQQRILEMNDKYVKKE---TCHQSTETDAVFLLESINGKSESPD 767
E+ KR D+++ L+ ++ + D+ ++ E + ++ ++++ K ++ D
Sbjct: 485 EDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTAD 544
Query: 768 HMVSQYQQALEEIERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQLDDVFRQLDKCS 827
+ Q Q+ +EIE LK++ +L + + + K E E+ + + + + +
Sbjct: 545 QLQEQLQRGKQEIENLKEEVESLNSLINDLQKDIEGSRKRE-SELLLFTERLTSKNAQLQ 603
Query: 828 IERDQYKSEVELLEMEKSQIRSQCEELKTEVEQLKS 863
E + +S+ + + +SQ++SQCE++K L+S
Sbjct: 604 SESNSLQSQFDKVSCSESQLQSQCEQMKQTNINLES 639
>gi|117553613 coiled-coil domain containing 151 [Homo sapiens]
Length = 595
Score = 50.4 bits (119), Expect = 8e-06
Identities = 68/302 (22%), Positives = 135/302 (44%), Gaps = 27/302 (8%)
Query: 643 EVPSLVVKKEETVEDEIDVRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQELRNQ 702
++ + ++ + +E+ +D +A ++ + E EA +H + + D A QLQ L
Sbjct: 232 QLKAYLMDESLNLENRLDSM-EAEVVRTKHELEA-LHVVNQEALNARDIAKNQLQYLEET 289
Query: 703 LLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFLLESINGK 762
L+ +++E Y +C ++ K+ +R M K ++ QS +T + +S++ K
Sbjct: 290 LVRERKKRERYISECKKRAEEKKLENER---MERKTHREHLLLQSDDT----IQDSLHAK 342
Query: 763 SESPDHMVSQYQQ-----ALEEIERLKKQCSALQHVKAECSQCSNNES-KSEMDEMAVQL 816
E S YQ +++ + S ++ A+ + E+ KSE ++ V+L
Sbjct: 343 EEELRQRWSMYQMEVIFGKVKDATGTDETHSLVRRFLAQGDTFAQLETLKSENEQTLVRL 402
Query: 817 DDVFRQLDKCSIERDQYKSEVELLEMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSS 876
+QL + +E +Y E L+ +K Q +Q E LK E + Q +
Sbjct: 403 KQEKQQLQR-ELEDLKYSGEATLVSQQKLQAEAQ-ERLKKEERRHAEAKDQLERALRAMQ 460
Query: 877 NIEESVNHMDGESLKLRSLRVNVGQLLAMIVPDLDLQQVNYDVDVVDEILGQVVEQMSEI 936
++S+ H+ + KL + V G+ +LD Q NY V +LG V E++ ++
Sbjct: 461 VAKDSLEHL---ASKLIHITVEDGRFAG---KELDPQADNY----VPNLLGLVEEKLLKL 510
Query: 937 SS 938
+
Sbjct: 511 QA 512
>gi|95089461 discs large homolog 5 [Homo sapiens]
Length = 1919
Score = 50.1 bits (118), Expect = 1e-05
Identities = 51/234 (21%), Positives = 100/234 (42%), Gaps = 22/234 (9%)
Query: 675 EAKIHETQETTDKSADDAG------CQLQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQ 728
EA HE + T ++ D +L ELR + +E E Y+ + + K++
Sbjct: 377 EAIHHELNKATAQNKDLQWEMELLQSELTELRTTQVKTAKESEKYREERDAVYSEYKLIM 436
Query: 729 ----QRILEMNDKYVKKETCH---QSTETDAVFLLESINGKSESPDHMVSQYQQALEEIE 781
Q I E++ + E +S+ ++ E + + D + +A +E+E
Sbjct: 437 SERDQVISELDKLQTEVELAESKLKSSTSEKKAANEEMEALRQIKDTVTMDAGRANKEVE 496
Query: 782 RLKKQCSAL-QHVK-----AECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKS 835
L+KQC AL Q +K A+ ++C + + E D++ + D + D ERD+ S
Sbjct: 497 ILRKQCKALCQELKEALQEADVAKCRRDWAFQERDKIVAERDSIRTLCDNLRRERDRAVS 556
Query: 836 EVELLEMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEESVNHMDGES 889
E+ R Q ++ E+++LK +Q + + + + + H +S
Sbjct: 557 ELAEALRSLDDTRKQKNDVSRELKELK---EQMESQLEKEARFRQLMAHSSHDS 607
Score = 39.3 bits (90), Expect = 0.017
Identities = 45/233 (19%), Positives = 101/233 (43%), Gaps = 26/233 (11%)
Query: 667 ILPSCVEAEAKIHETQETTDKSADDAGCQLQELRNQLLLVTEEKENYKRQCHMFTDQIKV 726
+L E ++HE + K D Q Q Q+L E + D+++V
Sbjct: 260 LLQQSWEDMKRLHEEDQ---KEIGDLRAQQQ----QVLKHNGSSEILNKLYDTAMDKLEV 312
Query: 727 LQQRILEMNDKYVKKETCHQSTETDAVFLLESINGKSESPDHMVSQYQQALEEIERLKKQ 786
+++ + +Y +K H + + LE + +++ Q + +L+ Q
Sbjct: 313 VKKDYDALRKRYSEKVAIHNAD----LSRLEQLGEENQRLLKQTEMLTQQRDTAIQLQHQ 368
Query: 787 CS-------ALQHVKAECSQCSNNESKSEMDEMAVQLDDV-------FRQLDKCSIERDQ 832
C+ A+ H + + N + + EM+ + +L ++ ++ +K ERD
Sbjct: 369 CALSLRRFEAIHH-ELNKATAQNKDLQWEMELLQSELTELRTTQVKTAKESEKYREERDA 427
Query: 833 YKSEVELLEMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEESVNHM 885
SE +L+ E+ Q+ S+ ++L+TEVE +S + + ++ ++ E++ +
Sbjct: 428 VYSEYKLIMSERDQVISELDKLQTEVELAESKLKSSTSEKKAANEEMEALRQI 480
>gi|41872583 Rho-associated, coiled-coil containing protein kinase 2
[Homo sapiens]
Length = 1388
Score = 49.7 bits (117), Expect = 1e-05
Identities = 64/324 (19%), Positives = 138/324 (42%), Gaps = 41/324 (12%)
Query: 595 DMKSEQSHVE-QGGVQVEFVGDSEPCGQTGSTSTSSSRCDQGNTAATQTEVPSLVVKKEE 653
D++ E+S++E Q++ + S + +T + D+ + E S +K+ E
Sbjct: 678 DLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLADKNKIYESIEEAKSEAMKEME 737
Query: 654 TV---EDEIDVRNDAVILPS---CVEAEAKIHETQETTDKSADDAGCQLQELRNQLLLVT 707
E + + + ++L + C + + ++Q+ ++ +++RN L +
Sbjct: 738 KKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLKQKDVLNEDVRNLTLKI- 796
Query: 708 EEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCH---------------QSTETDA 752
E+E KR +++ Q L+M++K +K+E H + DA
Sbjct: 797 -EQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELRKERQDA 855
Query: 753 VFLLESINGKSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECSQCSNNESKSEMDEM 812
++ + + E+ + + Y+ + E LK++C + E Q E + E D +
Sbjct: 856 DGQMKELQDQLEAEQYFSTLYKTQVRE---LKEECEEKTKLGKELQQ-KKQELQDERDSL 911
Query: 813 AVQLDDVFRQLDK----CSIERDQYK--------SEVELLEMEKSQIRSQCEELKTEVEQ 860
A QL+ + D SI +QY E+E+ EM ++ + + E +
Sbjct: 912 AAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEM-MARHKQELTEKDATIAS 970
Query: 861 LKSTNQQTATDVSTSSNIEESVNH 884
L+ TN+ +DV+ +N +E +N+
Sbjct: 971 LEETNRTLTSDVANLANEKEELNN 994
Score = 40.8 bits (94), Expect = 0.006
Identities = 77/428 (17%), Positives = 171/428 (39%), Gaps = 74/428 (17%)
Query: 559 LSSQFENSVYKGDDDDEDVIILEENSTPKPAVDHDIDMKSEQSHVEQGGVQVEFVGDSEP 618
LSS ++S + DD ++D +E PK V + + + E + DS
Sbjct: 375 LSSDIDSSNF--DDIEDDKGDVETFPIPKAFVGNQLPFIGFTYYREN-----LLLSDSPS 427
Query: 619 CGQTGSTSTSSSRCDQGNTAATQTEVPSLVVKKEETVEDEIDVRND----AVILPSCVEA 674
C +T S + + Q E+ + EE + +E+ + + + + +E
Sbjct: 428 CRETDSIQSRKNEESQ--------EIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLEK 479
Query: 675 EAKIHETQETTDKSADDAGCQLQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEM 734
AK E + T KS + A L++L + L+ + Y+R+ D+ + L+ + +
Sbjct: 480 TAKELEEEITLRKSVESA---LRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSL 536
Query: 735 NDKY--VKKETCHQSTETDAVFLLES--------INGKSESPDHMVSQYQQALEEIERLK 784
D+ +KK + T+ V L+ + +S++ + ++ ++I++L+
Sbjct: 537 KDQLEDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLE 596
Query: 785 KQCSALQHVKAECSQCSNNESKSEMDEMAVQLDDVFRQLDK----------------CSI 828
LQ C +K ++++ + L + C +
Sbjct: 597 SNNRDLQD-----KNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRICGL 651
Query: 829 ERDQYKSEVEL--LEMEKSQIRSQCEELKTE------------------VEQLKSTNQQT 868
E D ++ L +E+EK Q++ + +L+ E +EQ ++ ++ T
Sbjct: 652 EEDLKNGKILLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKAT 711
Query: 869 ATDVSTSSNIEESVNHMDGESLKLRSLRVNVGQLLAMIVPDLDLQQVNYDVDVVDEILGQ 928
++ + I ES+ E++K ++ + L V +L L + ++D L Q
Sbjct: 712 KARLADKNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVENL-LLEAEKRCSLLDCDLKQ 770
Query: 929 VVEQMSEI 936
++++E+
Sbjct: 771 SQQKINEL 778
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 49.7 bits (117), Expect = 1e-05
Identities = 59/295 (20%), Positives = 136/295 (46%), Gaps = 34/295 (11%)
Query: 650 KKEETVEDEI-----DVRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQE------ 698
KK E +E+EI ++N + ++ +A++ +T ET ++++ L++
Sbjct: 505 KKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLN 564
Query: 699 -----LRNQLLLVTEEK-ENYKRQCHMFTDQIKVLQQRI--LEMNDKYVKKETCHQSTET 750
LR + + E + ++ +++ + + IK ++ +E + +KKE H +
Sbjct: 565 QTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKG 624
Query: 751 DAVFLLESINGKSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECSQCS--NNESKSE 808
+ LE+ H+ + + ++I LK C ++ ++ E S+ N + K
Sbjct: 625 ERAEELEN------ELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKT 678
Query: 809 MDE---MAVQLDDVFR---QLDKCSIERDQYKSEVELLEMEKSQIRSQCEELKTEVEQLK 862
+D + QL+ + + QLD+ ++E + ++ M+ +Q++ + +EL++E EQLK
Sbjct: 679 LDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLK 738
Query: 863 STNQQTATDVSTSSNIEESVNHMDGESLKLRSLRVNVGQLLAMIVPDL-DLQQVN 916
+ + +E S +D E+ +L+ N + + + +L DL+ N
Sbjct: 739 KGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMEN 793
Score = 45.8 bits (107), Expect = 2e-04
Identities = 61/288 (21%), Positives = 132/288 (45%), Gaps = 29/288 (10%)
Query: 633 DQGNTAATQTEVPSLVVKKEETVEDEI-DVRNDAVILPSCVEAEA----KIHETQETTDK 687
+Q N QT V SL + + + E + D+ + IL ++ + KI + K
Sbjct: 557 EQENEHLNQT-VSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKK 615
Query: 688 SAD---DAGCQLQELRNQLLLVTEEKENYKRQC---HMFTDQIKVLQQRILEMNDKYVKK 741
+ + G + +EL N+L + +E E +++ + ++I+ L+Q E+ + K
Sbjct: 616 ELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKL 675
Query: 742 ETCHQSTETDAVFLLESINGKSESPDHMVSQYQQALEEIERLKKQCSALQ----HVKAEC 797
+ S + + F LES+ ++ D + ++ +E ++ + + LQ +++E
Sbjct: 676 KKTLDSFK-NLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEK 734
Query: 798 SQCSN-------NESKSEMDEMAVQLDDVFRQ-----LDKCSIERDQYKSEVELLEMEKS 845
Q + K+E E++ Q D+ Q L+ + + Q +SE++ LEME
Sbjct: 735 EQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQ 794
Query: 846 QIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEESVNHMDGESLKLR 893
++ EELK ++L+ ++ + +S +E+ ++ E+ +LR
Sbjct: 795 TLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLR 842
Score = 40.8 bits (94), Expect = 0.006
Identities = 62/258 (24%), Positives = 111/258 (43%), Gaps = 31/258 (12%)
Query: 671 CVEAEAKIHETQETTDKSADDAGCQLQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQR 730
C K E+++ DA +++ LR +L TE+ + K++ ++K LQQ
Sbjct: 235 CGSPGMKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQE 294
Query: 731 ILEMNDKYVKKETCHQSTETDAVFLLESINGKSESPDHMVSQYQQALEEIERLKKQCSAL 790
MN + E DA+ K ES VS+Y++ L +IE K + L
Sbjct: 295 --NMNLLSDARSARMYRDELDALREKAVRVDKLESE---VSRYKERLHDIEFYKARVEEL 349
Query: 791 QHVKAECSQCSNNESKSEMDEMAVQLDDVFRQLDKC-SIERD--QYKSEVELLEMEKSQI 847
+ E+K+ +++ QL+ + DK +E++ Q K+++ +EME+
Sbjct: 350 KEDNQVLL-----ETKTMLED---QLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMD 401
Query: 848 RSQCEELKTEVEQLKSTNQQTATD----------VSTSSNIEE----SVNHMDGESLKLR 893
R + EEL E L+ +Q+ + +S +S + E S+ H E R
Sbjct: 402 RKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSR 461
Query: 894 SLRVNV-GQLLAMIVPDL 910
L++ + Q L V +L
Sbjct: 462 LLKLEMENQSLTKTVEEL 479
Score = 33.1 bits (74), Expect = 1.2
Identities = 55/295 (18%), Positives = 109/295 (36%), Gaps = 39/295 (13%)
Query: 618 PCGQTGSTSTSSSRCDQGNTAATQTEVPSLVVKKEETVEDEIDVRNDAVILPSCVEAEAK 677
PCG G T S + A + ++ L + EE E +D + + + E +
Sbjct: 234 PCGSPGMKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELE------QMEIE 287
Query: 678 IHETQETTDKSADDAGC------QLQELRNQLLLVTE---EKENYKRQCHMFTDQIKVLQ 728
+ Q+ DA +L LR + + V + E YK + H + K
Sbjct: 288 LKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDI-EFYKARV 346
Query: 729 QRILEMNDKYVKKETCHQS------TETDAVFLLESINGKSESPDH-MVSQYQQALEEIE 781
+ + E N ++ +T + +D + LE N + ++ H M + ++IE
Sbjct: 347 EELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIE 406
Query: 782 RLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEVE--- 838
L ++ L+ + +S E + +L+ + R + + EV
Sbjct: 407 ELMEENMTLE--------MAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELT 458
Query: 839 -----LLEMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEESVNHMDGE 888
LEME + EEL+T V+ ++ + + + + V ++ E
Sbjct: 459 SSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENE 513
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 49.7 bits (117), Expect = 1e-05
Identities = 59/295 (20%), Positives = 136/295 (46%), Gaps = 34/295 (11%)
Query: 650 KKEETVEDEI-----DVRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQE------ 698
KK E +E+EI ++N + ++ +A++ +T ET ++++ L++
Sbjct: 505 KKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLN 564
Query: 699 -----LRNQLLLVTEEK-ENYKRQCHMFTDQIKVLQQRI--LEMNDKYVKKETCHQSTET 750
LR + + E + ++ +++ + + IK ++ +E + +KKE H +
Sbjct: 565 QTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKG 624
Query: 751 DAVFLLESINGKSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECSQCS--NNESKSE 808
+ LE+ H+ + + ++I LK C ++ ++ E S+ N + K
Sbjct: 625 ERAEELEN------ELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKT 678
Query: 809 MDE---MAVQLDDVFR---QLDKCSIERDQYKSEVELLEMEKSQIRSQCEELKTEVEQLK 862
+D + QL+ + + QLD+ ++E + ++ M+ +Q++ + +EL++E EQLK
Sbjct: 679 LDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLK 738
Query: 863 STNQQTATDVSTSSNIEESVNHMDGESLKLRSLRVNVGQLLAMIVPDL-DLQQVN 916
+ + +E S +D E+ +L+ N + + + +L DL+ N
Sbjct: 739 KGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMEN 793
Score = 45.8 bits (107), Expect = 2e-04
Identities = 61/288 (21%), Positives = 132/288 (45%), Gaps = 29/288 (10%)
Query: 633 DQGNTAATQTEVPSLVVKKEETVEDEI-DVRNDAVILPSCVEAEA----KIHETQETTDK 687
+Q N QT V SL + + + E + D+ + IL ++ + KI + K
Sbjct: 557 EQENEHLNQT-VSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKK 615
Query: 688 SAD---DAGCQLQELRNQLLLVTEEKENYKRQC---HMFTDQIKVLQQRILEMNDKYVKK 741
+ + G + +EL N+L + +E E +++ + ++I+ L+Q E+ + K
Sbjct: 616 ELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKL 675
Query: 742 ETCHQSTETDAVFLLESINGKSESPDHMVSQYQQALEEIERLKKQCSALQ----HVKAEC 797
+ S + + F LES+ ++ D + ++ +E ++ + + LQ +++E
Sbjct: 676 KKTLDSFK-NLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEK 734
Query: 798 SQCSN-------NESKSEMDEMAVQLDDVFRQ-----LDKCSIERDQYKSEVELLEMEKS 845
Q + K+E E++ Q D+ Q L+ + + Q +SE++ LEME
Sbjct: 735 EQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQ 794
Query: 846 QIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEESVNHMDGESLKLR 893
++ EELK ++L+ ++ + +S +E+ ++ E+ +LR
Sbjct: 795 TLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLR 842
Score = 40.8 bits (94), Expect = 0.006
Identities = 62/258 (24%), Positives = 111/258 (43%), Gaps = 31/258 (12%)
Query: 671 CVEAEAKIHETQETTDKSADDAGCQLQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQR 730
C K E+++ DA +++ LR +L TE+ + K++ ++K LQQ
Sbjct: 235 CGSPGMKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQE 294
Query: 731 ILEMNDKYVKKETCHQSTETDAVFLLESINGKSESPDHMVSQYQQALEEIERLKKQCSAL 790
MN + E DA+ K ES VS+Y++ L +IE K + L
Sbjct: 295 --NMNLLSDARSARMYRDELDALREKAVRVDKLESE---VSRYKERLHDIEFYKARVEEL 349
Query: 791 QHVKAECSQCSNNESKSEMDEMAVQLDDVFRQLDKC-SIERD--QYKSEVELLEMEKSQI 847
+ E+K+ +++ QL+ + DK +E++ Q K+++ +EME+
Sbjct: 350 KEDNQVLL-----ETKTMLED---QLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMD 401
Query: 848 RSQCEELKTEVEQLKSTNQQTATD----------VSTSSNIEE----SVNHMDGESLKLR 893
R + EEL E L+ +Q+ + +S +S + E S+ H E R
Sbjct: 402 RKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSR 461
Query: 894 SLRVNV-GQLLAMIVPDL 910
L++ + Q L V +L
Sbjct: 462 LLKLEMENQSLTKTVEEL 479
Score = 33.1 bits (74), Expect = 1.2
Identities = 55/295 (18%), Positives = 109/295 (36%), Gaps = 39/295 (13%)
Query: 618 PCGQTGSTSTSSSRCDQGNTAATQTEVPSLVVKKEETVEDEIDVRNDAVILPSCVEAEAK 677
PCG G T S + A + ++ L + EE E +D + + + E +
Sbjct: 234 PCGSPGMKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELE------QMEIE 287
Query: 678 IHETQETTDKSADDAGC------QLQELRNQLLLVTE---EKENYKRQCHMFTDQIKVLQ 728
+ Q+ DA +L LR + + V + E YK + H + K
Sbjct: 288 LKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDI-EFYKARV 346
Query: 729 QRILEMNDKYVKKETCHQS------TETDAVFLLESINGKSESPDH-MVSQYQQALEEIE 781
+ + E N ++ +T + +D + LE N + ++ H M + ++IE
Sbjct: 347 EELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIE 406
Query: 782 RLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEVE--- 838
L ++ L+ + +S E + +L+ + R + + EV
Sbjct: 407 ELMEENMTLE--------MAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELT 458
Query: 839 -----LLEMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEESVNHMDGE 888
LEME + EEL+T V+ ++ + + + + V ++ E
Sbjct: 459 SSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENE 513
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 49.3 bits (116), Expect = 2e-05
Identities = 53/259 (20%), Positives = 114/259 (44%), Gaps = 16/259 (6%)
Query: 696 LQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFL 755
+ +L L EK+ R+ T+Q + LQ + ++ + + H ST D +
Sbjct: 207 ITQLTANLQQARREKDETMREFLELTEQSQKLQIQFQQLQASETLRNSTHSSTAADLLQA 266
Query: 756 LESI---NGKSESPDHMVSQYQQALE----EIERLKKQCSALQHVKAECSQCSNNESKSE 808
+ I + E DH++ YQ+ E +I L+++ + + + + SN E E
Sbjct: 267 KQQILTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQE 326
Query: 809 MDEMAVQLDDVFRQLDKCSIE-RDQYKSEVELLEMEKSQIRSQCEELKT---EVEQLKST 864
+ + +L+ + +K ++E +D+ + +LL + QI + +E+K E+ K
Sbjct: 327 KETIIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQK 386
Query: 865 NQQTATDVSTSSNIEESV---NHMDG--ESLKLRSLRVNVGQLLAMIVPDLDLQQVNYDV 919
+Q++ ++ E + NH D E+ ++ + + L + +LD V
Sbjct: 387 ERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIV 446
Query: 920 DVVDEILGQVVEQMSEISS 938
+ E++ Q + QM E+ +
Sbjct: 447 QMKQELIRQHMAQMEEMKT 465
Score = 45.4 bits (106), Expect = 2e-04
Identities = 43/224 (19%), Positives = 101/224 (45%), Gaps = 23/224 (10%)
Query: 639 ATQTEVPSLVVKKEETVEDEIDVRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQE 698
+T ++ + +V E+ E++++++A + ++ E E D+ A+ +L+
Sbjct: 566 STVEDLKAEIVSASES-RKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELER 624
Query: 699 LRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTETDAV--FLL 756
LR QLL EE+ + ++ +I + +K H + D + +
Sbjct: 625 LRTQLLFSHEEELSKLKEDLEIEHRINI---------EKLKDNLGIHYKQQIDGLQNEMS 675
Query: 757 ESINGKSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQL 816
+ I D+++++ Q + EI +LK +L + K+E NE + E+
Sbjct: 676 QKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEI------- 728
Query: 817 DDVFRQLDKCSIERDQYKSEVELLEMEKSQIRSQCEELKTEVEQ 860
++ RQ +K E+ + EV+ L+++ + Q +E + ++++
Sbjct: 729 -EILRQEEK---EKGTLEQEVQELQLKTELLEKQMKEKENDLQE 768
Score = 42.4 bits (98), Expect = 0.002
Identities = 64/307 (20%), Positives = 133/307 (43%), Gaps = 28/307 (9%)
Query: 650 KKEETVEDEIDVRNDAVILPSCVEAEAKIHETQETTDKS--ADDAGCQLQELRNQLLLVT 707
+K+ET+ + +++ + L + + +T S AD + Q L +Q L
Sbjct: 220 EKDETMREFLELTEQSQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQQILTHQQQLEE 279
Query: 708 EEK--ENYKRQCHMFTDQIKVLQQRI--LEM-NDKYVKKETCHQSTETDAVF------LL 756
++ E+Y+++ FT QI LQ++I EM DK V+ + E + + ++
Sbjct: 280 QDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKII 339
Query: 757 ESINGKSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQL 816
E E D + + + E E++ ++ ++++K E + E +S E QL
Sbjct: 340 EEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQS--SEEIKQL 397
Query: 817 DDVFRQLDKCSIERDQYKSEVELLEMEKSQIRSQCEELKTEVEQLKSTN----QQTATDV 872
+L K + + Q+ E ++++ + + + + E+L+ E++++ +Q
Sbjct: 398 MGTVEELQKRNHKDSQF--ETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQ 455
Query: 873 STSSNIEESVNHMDGESLKLRS---LRVNVGQLLAMIVP----DLDLQQVNYDVDVVDEI 925
+ E H LRS + VN Q+ M V ++ LQ N + + E
Sbjct: 456 HMAQMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEE 515
Query: 926 LGQVVEQ 932
LG ++E+
Sbjct: 516 LGLILEE 522
Score = 41.6 bits (96), Expect = 0.004
Identities = 43/221 (19%), Positives = 102/221 (46%), Gaps = 22/221 (9%)
Query: 691 DAGCQLQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKET----CHQ 746
D Q ++L+ +L L+ EEK +RQ +++ +++I ++E+ H+
Sbjct: 504 DTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHK 563
Query: 747 STETDAVFLLESINGKSESPDHMVSQYQQALE----EIERLKKQCSALQHVKAECSQCSN 802
S T E ++ SES + +++ + ++E L+K+ +A+ AE +
Sbjct: 564 SLSTVEDLKAEIVSA-SESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAEL 622
Query: 803 NESKSEM----DEMAVQLDDVFRQLDKCSIER------DQYKSEVELLEMEKSQIRSQCE 852
++++ +E +L + + +IE+ YK +++ L+ E SQ + E
Sbjct: 623 ERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQNEMSQ---KIE 679
Query: 853 ELKTEVEQLKSTNQQTATDVSTSSNIEESVNHMDGESLKLR 893
++ E + L + Q ++S ++++S+ + E + L+
Sbjct: 680 TMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQ 720
Score = 39.7 bits (91), Expect = 0.013
Identities = 53/242 (21%), Positives = 94/242 (38%), Gaps = 46/242 (19%)
Query: 673 EAEAKIHETQETTDKSADDAGCQL-QELRNQLLLVTEEK--------ENYKRQCHMFT-- 721
E + K+ + + D+ Q+ QEL Q + EE EN R T
Sbjct: 425 ETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNITVN 484
Query: 722 -DQIKVLQQRILEMNDKYVKKETCHQSTETDAVFLLESINGKSESPDHMVSQYQQALEEI 780
DQIK++ I E+N K + + + + +LE + +V + + E+I
Sbjct: 485 EDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSREQI 544
Query: 781 ERLK--------------KQCSALQHVKAECSQCSNNESKSEMDEMAVQLDDVFRQLDKC 826
+R + K S ++ +KAE S + + E+ K
Sbjct: 545 QRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELEL---------------KH 589
Query: 827 SIERDQYKSEVELLEMEKSQI-----RSQCEELKTEVEQLKSTNQQTATDVSTSSNIEES 881
E YK ++E+LE EK+ + SQ EL+ QL ++++ + + IE
Sbjct: 590 EAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHR 649
Query: 882 VN 883
+N
Sbjct: 650 IN 651
Score = 38.9 bits (89), Expect = 0.023
Identities = 75/348 (21%), Positives = 144/348 (41%), Gaps = 38/348 (10%)
Query: 550 SILNAKNRRLSSQFENSVYKGD--DDDEDVIILEENSTPKPAVDHDIDMKSE-QSHVEQG 606
S + + LS + S + G D + + ++L +S + AV+ ++ SE S +E
Sbjct: 1812 SKVTEEGTELSQRLVRSGFAGTEIDPENEELMLNISSRLQAAVEKLLEAISETSSQLEHA 1871
Query: 607 GV-QVEFVGDSEPCGQTGSTSTSSSRCDQG-----NTAATQTEVPSLVVKKEETVEDEID 660
V Q E + +S Q +T S +C + + + E ++ + K E V ID
Sbjct: 1872 KVTQTELMRESFRQKQE---ATESLKCQEELRERLHEESRAREQLAVELSKAEGV---ID 1925
Query: 661 VRNDAVILPSCVEAEAKIHETQETTDKSADDAGC---QLQELRNQLLLVTEEKENYKRQC 717
D L E +I E + D+ + C +LQEL + + EE+E RQ
Sbjct: 1926 GYADEKTL-----FERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQK 1980
Query: 718 HMFTDQIKVLQQRILEMNDKYVKKE---TCHQSTETDAVFLLESINGKSESPDHMVSQY- 773
+ ++Q++L+ +K +K++ C D L + + + VS++
Sbjct: 1981 EAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDD--LQKQVKALEIDVEEQVSRFI 2038
Query: 774 ---QQALEEIERLKKQCSALQHV-----KAECSQCSNNESKSEMDEMAVQ-LDDVFRQLD 824
Q+ E+ L++Q AL+ K Q + E + ++ + +Q L+ + +
Sbjct: 2039 ELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVP 2098
Query: 825 KCSIERDQYKSEVELLEMEKSQIRSQCEELKTEVEQLKSTNQQTATDV 872
+ + EVE L + +C EL EQL+ Q+ ++
Sbjct: 2099 RFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEI 2146
Score = 32.7 bits (73), Expect = 1.6
Identities = 59/254 (23%), Positives = 108/254 (42%), Gaps = 56/254 (22%)
Query: 657 DEIDVRNDAVI--------LPSCVEAE-AKIHETQETTDKSADDAGCQLQE--------- 698
DE+ + ND + L +E E AK+ ++E + +D L+
Sbjct: 3201 DEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSLESQKQRNLQLN 3260
Query: 699 --LRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEM-----NDKYVKKE---TCHQST 748
L Q L+ E ++ + Q ++ Q+ Q R LE+ ++K +E T +
Sbjct: 3261 LLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQVLLESEKVRIREMSSTLDRER 3320
Query: 749 ETDAVFLLESINGKSESP---DHMVSQYQQALEE-----IERL----KKQCSALQ----- 791
E A G+S P + ++ + Q+ LEE +E L K + +LQ
Sbjct: 3321 ELHAQLQSSDGTGQSRPPLPSEDLLKELQKQLEEKHSRIVELLNETEKYKLDSLQTRQQM 3380
Query: 792 ------HVKA-ECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQ-YKSEVELLEME 843
H K + Q +N E + +M E+ +++D+ RQL++ +R Q YK ++E ++
Sbjct: 3381 EKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQLEE---KRQQVYKLDLEGQRLQ 3437
Query: 844 KSQIRSQCEELKTE 857
Q +EL+ E
Sbjct: 3438 GIMQEFQKQELERE 3451
Score = 32.0 bits (71), Expect = 2.8
Identities = 53/280 (18%), Positives = 110/280 (39%), Gaps = 54/280 (19%)
Query: 672 VEAEAKIHETQETTDKSADDAGCQLQELRN------QLLLVTEEKENYKRQCHMFTDQIK 725
++ EA+++++ ++ + +D G L L+ +LL E +
Sbjct: 3003 LQREAEVYDSSQSHESFSDWRGELLLALQQVFLEERSVLLAAFRTELTALGTTDAVGLLN 3062
Query: 726 VLQQRILEMNDKYVKKETCHQSTETDAVF-----LLESINGK---------SESPDHMVS 771
L+QRI E +Y C Q + ++ L +NG+ SE P +
Sbjct: 3063 CLEQRIQEQGVEYQAAMECLQKADRRSLLSEIQALHAQMNGRKITLKREQESEKPSQELL 3122
Query: 772 QY--QQALEEIERLKKQCSALQHVKAECSQCSNNES------KSEMDEMAVQLDDVFRQL 823
+Y QQ ++ ++ + S+++ E + ++E KSE+ + ++L+ +
Sbjct: 3123 EYNIQQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETTLKAQ 3182
Query: 824 DKCSIERDQYKSEVE-------------------------LLEMEKSQIRSQCEELKTEV 858
K E + ++ EV+ LE EK+++ E K E+
Sbjct: 3183 HKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEEL 3242
Query: 859 EQLK-STNQQTATDVSTSSNIEESVNHMDGESLKLRSLRV 897
E LK S Q ++ + +E+ ++ K+ S R+
Sbjct: 3243 EDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQRM 3282
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 49.3 bits (116), Expect = 2e-05
Identities = 53/259 (20%), Positives = 114/259 (44%), Gaps = 16/259 (6%)
Query: 696 LQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFL 755
+ +L L EK+ R+ T+Q + LQ + ++ + + H ST D +
Sbjct: 207 ITQLTANLQQARREKDETMREFLELTEQSQKLQIQFQQLQASETLRNSTHSSTAADLLQA 266
Query: 756 LESI---NGKSESPDHMVSQYQQALE----EIERLKKQCSALQHVKAECSQCSNNESKSE 808
+ I + E DH++ YQ+ E +I L+++ + + + + SN E E
Sbjct: 267 KQQILTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQE 326
Query: 809 MDEMAVQLDDVFRQLDKCSIE-RDQYKSEVELLEMEKSQIRSQCEELKT---EVEQLKST 864
+ + +L+ + +K ++E +D+ + +LL + QI + +E+K E+ K
Sbjct: 327 KETIIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQK 386
Query: 865 NQQTATDVSTSSNIEESV---NHMDG--ESLKLRSLRVNVGQLLAMIVPDLDLQQVNYDV 919
+Q++ ++ E + NH D E+ ++ + + L + +LD V
Sbjct: 387 ERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIV 446
Query: 920 DVVDEILGQVVEQMSEISS 938
+ E++ Q + QM E+ +
Sbjct: 447 QMKQELIRQHMAQMEEMKT 465
Score = 45.4 bits (106), Expect = 2e-04
Identities = 43/224 (19%), Positives = 101/224 (45%), Gaps = 23/224 (10%)
Query: 639 ATQTEVPSLVVKKEETVEDEIDVRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQE 698
+T ++ + +V E+ E++++++A + ++ E E D+ A+ +L+
Sbjct: 566 STVEDLKAEIVSASES-RKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELER 624
Query: 699 LRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTETDAV--FLL 756
LR QLL EE+ + ++ +I + +K H + D + +
Sbjct: 625 LRTQLLFSHEEELSKLKEDLEIEHRINI---------EKLKDNLGIHYKQQIDGLQNEMS 675
Query: 757 ESINGKSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQL 816
+ I D+++++ Q + EI +LK +L + K+E NE + E+
Sbjct: 676 QKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEI------- 728
Query: 817 DDVFRQLDKCSIERDQYKSEVELLEMEKSQIRSQCEELKTEVEQ 860
++ RQ +K E+ + EV+ L+++ + Q +E + ++++
Sbjct: 729 -EILRQEEK---EKGTLEQEVQELQLKTELLEKQMKEKENDLQE 768
Score = 42.4 bits (98), Expect = 0.002
Identities = 64/307 (20%), Positives = 133/307 (43%), Gaps = 28/307 (9%)
Query: 650 KKEETVEDEIDVRNDAVILPSCVEAEAKIHETQETTDKS--ADDAGCQLQELRNQLLLVT 707
+K+ET+ + +++ + L + + +T S AD + Q L +Q L
Sbjct: 220 EKDETMREFLELTEQSQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQQILTHQQQLEE 279
Query: 708 EEK--ENYKRQCHMFTDQIKVLQQRI--LEM-NDKYVKKETCHQSTETDAVF------LL 756
++ E+Y+++ FT QI LQ++I EM DK V+ + E + + ++
Sbjct: 280 QDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKII 339
Query: 757 ESINGKSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQL 816
E E D + + + E E++ ++ ++++K E + E +S E QL
Sbjct: 340 EEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQS--SEEIKQL 397
Query: 817 DDVFRQLDKCSIERDQYKSEVELLEMEKSQIRSQCEELKTEVEQLKSTN----QQTATDV 872
+L K + + Q+ E ++++ + + + + E+L+ E++++ +Q
Sbjct: 398 MGTVEELQKRNHKDSQF--ETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQ 455
Query: 873 STSSNIEESVNHMDGESLKLRS---LRVNVGQLLAMIVP----DLDLQQVNYDVDVVDEI 925
+ E H LRS + VN Q+ M V ++ LQ N + + E
Sbjct: 456 HMAQMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEE 515
Query: 926 LGQVVEQ 932
LG ++E+
Sbjct: 516 LGLILEE 522
Score = 41.6 bits (96), Expect = 0.004
Identities = 43/221 (19%), Positives = 102/221 (46%), Gaps = 22/221 (9%)
Query: 691 DAGCQLQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKET----CHQ 746
D Q ++L+ +L L+ EEK +RQ +++ +++I ++E+ H+
Sbjct: 504 DTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHK 563
Query: 747 STETDAVFLLESINGKSESPDHMVSQYQQALE----EIERLKKQCSALQHVKAECSQCSN 802
S T E ++ SES + +++ + ++E L+K+ +A+ AE +
Sbjct: 564 SLSTVEDLKAEIVSA-SESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAEL 622
Query: 803 NESKSEM----DEMAVQLDDVFRQLDKCSIER------DQYKSEVELLEMEKSQIRSQCE 852
++++ +E +L + + +IE+ YK +++ L+ E SQ + E
Sbjct: 623 ERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQNEMSQ---KIE 679
Query: 853 ELKTEVEQLKSTNQQTATDVSTSSNIEESVNHMDGESLKLR 893
++ E + L + Q ++S ++++S+ + E + L+
Sbjct: 680 TMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQ 720
Score = 39.7 bits (91), Expect = 0.013
Identities = 53/242 (21%), Positives = 94/242 (38%), Gaps = 46/242 (19%)
Query: 673 EAEAKIHETQETTDKSADDAGCQL-QELRNQLLLVTEEK--------ENYKRQCHMFT-- 721
E + K+ + + D+ Q+ QEL Q + EE EN R T
Sbjct: 425 ETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNITVN 484
Query: 722 -DQIKVLQQRILEMNDKYVKKETCHQSTETDAVFLLESINGKSESPDHMVSQYQQALEEI 780
DQIK++ I E+N K + + + + +LE + +V + + E+I
Sbjct: 485 EDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSREQI 544
Query: 781 ERLK--------------KQCSALQHVKAECSQCSNNESKSEMDEMAVQLDDVFRQLDKC 826
+R + K S ++ +KAE S + + E+ K
Sbjct: 545 QRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELEL---------------KH 589
Query: 827 SIERDQYKSEVELLEMEKSQI-----RSQCEELKTEVEQLKSTNQQTATDVSTSSNIEES 881
E YK ++E+LE EK+ + SQ EL+ QL ++++ + + IE
Sbjct: 590 EAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHR 649
Query: 882 VN 883
+N
Sbjct: 650 IN 651
Score = 39.7 bits (91), Expect = 0.013
Identities = 88/400 (22%), Positives = 166/400 (41%), Gaps = 46/400 (11%)
Query: 550 SILNAKNRRLSSQFENSVYKGD--DDDEDVIILEENSTPKPAVDHDIDMKSE-QSHVEQG 606
S + + LS + S + G D + + ++L +S + AV+ ++ SE S +E
Sbjct: 1812 SKVTEEGTELSQRLVRSGFAGTEIDPENEELMLNISSRLQAAVEKLLEAISETSSQLEHA 1871
Query: 607 GV-QVEFVGDSEPCGQTGSTSTSSSRCDQG-----NTAATQTEVPSLVVKKEETVEDEID 660
V Q E + +S Q +T S +C + + + E ++ + K E V ID
Sbjct: 1872 KVTQTELMRESFRQKQE---ATESLKCQEELRERLHEESRAREQLAVELSKAEGV---ID 1925
Query: 661 VRNDAVILPSCVEAEAKIHETQETTDKSADDAGC---QLQELRNQLLLVTEEKENYKRQC 717
D L E +I E + D+ + C +LQEL + + EE+E RQ
Sbjct: 1926 GYADEKTL-----FERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQK 1980
Query: 718 HMFTDQIKVLQQRILEMNDKYVKKE---TCHQSTETDAVFLLESINGKSESPDHMVSQY- 773
+ ++Q++L+ +K +K++ C D L + + + VS++
Sbjct: 1981 EAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDD--LQKQVKALEIDVEEQVSRFI 2038
Query: 774 ---QQALEEIERLKKQCSALQHV-----KAECSQCSNNESKSEMDEMAVQ-LDDVFRQLD 824
Q+ E+ L++Q AL+ K Q + E + ++ + +Q L+ + +
Sbjct: 2039 ELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVP 2098
Query: 825 KCSIERDQYKSEVELLEMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEESVNH 884
+ + EVE L + +C EL EQL+ Q+ ++ +E V
Sbjct: 2099 RFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEI---EKLEFRVRE 2155
Query: 885 MDGESLKLRSLRVNVGQLLAMIVPDLDLQ-QVNYDVDVVD 923
+ E L R + G + A P+L L+ Q+ + D +D
Sbjct: 2156 L--EQALLVEDRKHFGAVEAK--PELSLEVQLQAERDAID 2191
Score = 32.7 bits (73), Expect = 1.6
Identities = 59/254 (23%), Positives = 108/254 (42%), Gaps = 56/254 (22%)
Query: 657 DEIDVRNDAVI--------LPSCVEAE-AKIHETQETTDKSADDAGCQLQE--------- 698
DE+ + ND + L +E E AK+ ++E + +D L+
Sbjct: 3193 DEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSLESQKQRNLQLN 3252
Query: 699 --LRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEM-----NDKYVKKE---TCHQST 748
L Q L+ E ++ + Q ++ Q+ Q R LE+ ++K +E T +
Sbjct: 3253 LLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQVLLESEKVRIREMSSTLDRER 3312
Query: 749 ETDAVFLLESINGKSESP---DHMVSQYQQALEE-----IERL----KKQCSALQ----- 791
E A G+S P + ++ + Q+ LEE +E L K + +LQ
Sbjct: 3313 ELHAQLQSSDGTGQSRPPLPSEDLLKELQKQLEEKHSRIVELLNETEKYKLDSLQTRQQM 3372
Query: 792 ------HVKA-ECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQ-YKSEVELLEME 843
H K + Q +N E + +M E+ +++D+ RQL++ +R Q YK ++E ++
Sbjct: 3373 EKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQLEE---KRQQVYKLDLEGQRLQ 3429
Query: 844 KSQIRSQCEELKTE 857
Q +EL+ E
Sbjct: 3430 GIMQEFQKQELERE 3443
Score = 32.0 bits (71), Expect = 2.8
Identities = 53/280 (18%), Positives = 110/280 (39%), Gaps = 54/280 (19%)
Query: 672 VEAEAKIHETQETTDKSADDAGCQLQELRN------QLLLVTEEKENYKRQCHMFTDQIK 725
++ EA+++++ ++ + +D G L L+ +LL E +
Sbjct: 2995 LQREAEVYDSSQSHESFSDWRGELLLALQQVFLEERSVLLAAFRTELTALGTTDAVGLLN 3054
Query: 726 VLQQRILEMNDKYVKKETCHQSTETDAVF-----LLESINGK---------SESPDHMVS 771
L+QRI E +Y C Q + ++ L +NG+ SE P +
Sbjct: 3055 CLEQRIQEQGVEYQAAMECLQKADRRSLLSEIQALHAQMNGRKITLKREQESEKPSQELL 3114
Query: 772 QY--QQALEEIERLKKQCSALQHVKAECSQCSNNES------KSEMDEMAVQLDDVFRQL 823
+Y QQ ++ ++ + S+++ E + ++E KSE+ + ++L+ +
Sbjct: 3115 EYNIQQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETTLKAQ 3174
Query: 824 DKCSIERDQYKSEVE-------------------------LLEMEKSQIRSQCEELKTEV 858
K E + ++ EV+ LE EK+++ E K E+
Sbjct: 3175 HKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEEL 3234
Query: 859 EQLK-STNQQTATDVSTSSNIEESVNHMDGESLKLRSLRV 897
E LK S Q ++ + +E+ ++ K+ S R+
Sbjct: 3235 EDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQRM 3274
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 49.3 bits (116), Expect = 2e-05
Identities = 77/413 (18%), Positives = 163/413 (39%), Gaps = 50/413 (12%)
Query: 511 RHLSEGTNSYATRLLNNHQVPPQSEPESNSLKRRLSTRSSILNAKNRRLSSQFENSVYKG 570
R L + +Y TR+L E ES S S+ KN+ K
Sbjct: 556 RDLQQEAETYRTRIL---------ELES-------SLEKSLQENKNQSKDLAVHLEAEKN 599
Query: 571 DDDDEDVIILEENSTPKPAVDHDID-MKSEQSHVEQGGVQVEFVGDSEPCGQTGSTSTSS 629
+ E +++E++ T ++ H D + +E+ V + Q E E C Q T
Sbjct: 600 KHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKD 659
Query: 630 SRCDQGNTAATQTEVPSLVVKKEETVEDEIDVRNDAV--ILPSCVEAEAKIHETQETTDK 687
A E+ ++K + + E++ + + +L + + E ++ ++ TDK
Sbjct: 660 KEII---FQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDK 716
Query: 688 SADDAGCQLQELRNQLL-----LVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKE 742
+ ++ E +N ++ E + + +R DQI L+ +L+ DK++K+
Sbjct: 717 MKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLEL-LLKERDKHLKEH 775
Query: 743 TCH-QSTETDAVFLLESINGKSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECS--- 798
H ++ E D + S D S E+ + ++Q + LQ +
Sbjct: 776 QAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETER 835
Query: 799 ----------QCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQ--------YKSEVELL 840
+ + +E+D +Q+ D+ +QL+K + E +Q Y+S++E
Sbjct: 836 ILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDG 895
Query: 841 EMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEESVNHMDGESLKLR 893
E+ Q + E + + Q++ ++ ++ + +E H+ E + +
Sbjct: 896 NKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETK 948
Score = 47.8 bits (112), Expect = 5e-05
Identities = 77/359 (21%), Positives = 148/359 (41%), Gaps = 45/359 (12%)
Query: 535 EPESNSLKRRLSTRSSILNAKNRRLSSQFENSVYKGDDDDEDVIILEENSTPKPAVDHDI 594
E + S+K L T+ L N + S+ E K +D LE S K A ++
Sbjct: 1591 ENQVYSMKAELETKKKELEHVNLSVKSKEEE--LKALEDR-----LESESAAKLA---EL 1640
Query: 595 DMKSEQSHVEQGGVQVEFVGDSEPCGQTGSTSTSSSRCDQGNTAATQTEVPSLVVKKEET 654
K+EQ + ++ + + E + T S + + ++ +K ++
Sbjct: 1641 KRKAEQ---KIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKS 1697
Query: 655 VEDEIDVRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQELRNQLLLVTEEKENYK 714
VE +++ +I+P + A E +E AD GC +Q+ + + V +
Sbjct: 1698 VESS---QSETLIVPRSAKNVAAYTEQEE-----ADSQGC-VQKTYEEKISVLQRN---- 1744
Query: 715 RQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFLLESINGKSESPDHMVSQYQ 774
T++ K+LQ R+ + ++ V + + + LE K M+ Q
Sbjct: 1745 -----LTEKEKLLQ-RVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQ 1798
Query: 775 QALEEIERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQLDDVFRQLDK----CSIER 830
+ LEE + K QHV+ E + +N ++K ++ + DDV + L + C I
Sbjct: 1799 EELEEKNK-KYSLIVAQHVEKEGGK-NNIQAKQNLENV---FDDVQKTLQEKELTCQILE 1853
Query: 831 DQYKSEVELLEMEKSQIRSQCEELKTEVEQLKSTNQQTA----TDVSTSSNIEESVNHM 885
+ K L +K R + EEL ++ E+L++ Q T++ + E+S +H+
Sbjct: 1854 QKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHL 1912
Score = 44.3 bits (103), Expect = 5e-04
Identities = 44/227 (19%), Positives = 106/227 (46%), Gaps = 11/227 (4%)
Query: 673 EAEAKIHETQETTDKSADDAGCQLQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRIL 732
E + ++HET E ++ +++++ Q + E+KE +R ++ Q+
Sbjct: 368 ETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTE 427
Query: 733 EMNDKYVKK-----ETCHQSTETDAVFLLESING-KSESPDHMVSQYQQALEEIERLKKQ 786
E K + +T +++E + + L + ++ K E D M ++ + ++++L ++
Sbjct: 428 EARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEK 487
Query: 787 CSALQHVKAECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKS-EVELLEMEKS 845
L + E ++ + ++M V L+ + K S E++Q +S +E LE++K
Sbjct: 488 --ELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKK 545
Query: 846 QIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEESVNHMDGESLKL 892
I ++ E +++Q T + ++ S++E+S+ +S L
Sbjct: 546 AILTESENKLRDLQQEAETYRTRILEL--ESSLEKSLQENKNQSKDL 590
Score = 40.4 bits (93), Expect = 0.008
Identities = 51/263 (19%), Positives = 116/263 (44%), Gaps = 36/263 (13%)
Query: 641 QTEVPSLVVKKEETVEDEIDVRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQELR 700
+ ++ SLV +KE ++ + + A SC+ K +L E
Sbjct: 1310 KADIESLVTEKEALQKEGGNQQQAASEKESCITQLKK-----------------ELSENI 1352
Query: 701 NQLLLVTEEKENYKRQCHMFTDQIKVLQ---QRILEMNDKYVKKETCHQSTETDAVFLLE 757
N + L+ EE + K + + Q+ L Q + +++K + + + + LL+
Sbjct: 1353 NAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLD 1412
Query: 758 SINGKSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQLD 817
+ S D + + ALE+++ + S + + +Q + ++ + E+ +QL+
Sbjct: 1413 QVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWK----KKAQSRFTQHQNTVKELQIQLE 1468
Query: 818 DVFRQLDKCSIERDQYKSEVELLEMEKSQIRSQCEELKTEVEQLKSTNQQTATDVST--- 874
K + E+D+ ++ LL+ E Q + + LK E+E KS ++ +++ T
Sbjct: 1469 ----LKSKEAYEKDE---QINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELK 1521
Query: 875 --SSNIEESVNHMDGESLKLRSL 895
++ I E +H+ +++++ SL
Sbjct: 1522 SQTARIMELEDHITQKTIEIESL 1544
Score = 39.7 bits (91), Expect = 0.013
Identities = 44/209 (21%), Positives = 89/209 (42%), Gaps = 19/209 (9%)
Query: 684 TTDKSADDAGCQLQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKET 743
T+ K+ + +++ N L E +++K QC + T + + LQ+++ E + K +
Sbjct: 276 TSVKTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKD 335
Query: 744 CHQSTET-------DAVFLLESINGK-----SESPDHMVSQYQQALEEIERLKKQCSALQ 791
H + +T DA L+E + +E+ M + EEI +L+ S ++
Sbjct: 336 LHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLR---SRIK 392
Query: 792 HVKAECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEVELLEMEKSQIRSQC 851
+ + + + KSE +L+ K R + K+E ++ + I
Sbjct: 393 QMTTQGEELREQKEKSERAAFE-ELEKALSTAQKTEEARRKLKAE---MDEQIKTIEKTS 448
Query: 852 EELKTEVEQLKSTNQQTATDVSTSSNIEE 880
EE + ++Q S +Q DV S+ E+
Sbjct: 449 EEERISLQQELSRVKQEVVDVMKKSSEEQ 477
Score = 37.0 bits (84), Expect = 0.086
Identities = 48/233 (20%), Positives = 101/233 (43%), Gaps = 19/233 (8%)
Query: 641 QTEVPSLVVKKEETVE-DEIDVRNDAV-ILPSCVEAEAKIHETQETTDKSADDAGCQLQE 698
+ E+ L K E+ ++D RN +L E ++K H Q K + Q +
Sbjct: 1871 RVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQP---KLLSNMEAQHND 1927
Query: 699 LRNQLLLVTEEKENYKRQCHMFTDQIKVLQ---QRILEMNDKYVKKETCHQSTETDAVFL 755
L +L EK+ ++ +++L+ Q+ LE+ K +E + +
Sbjct: 1928 LEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLE 1987
Query: 756 LESINGKSESPDHMVSQYQQALEEIER-LKKQCSALQHVKAECSQCSNNESKSEMDEMAV 814
L+ + + +Q Q +E+E +K+ + Q V+AE + E+ + ++A
Sbjct: 1988 LKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAE 2047
Query: 815 QLDDVFRQLDKCSIERDQYKSEVELLEMEKSQIRSQCEELKTEVEQLKSTNQQ 867
+ DD+ R K E+L+ + ++ ++ +L+T++E+L+ QQ
Sbjct: 2048 KDDDLKRTA----------KRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQ 2090
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,806,631
Number of Sequences: 37866
Number of extensions: 1622104
Number of successful extensions: 6860
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 109
Number of HSP's successfully gapped in prelim test: 509
Number of HSP's that attempted gapping in prelim test: 5142
Number of HSP's gapped (non-prelim): 1734
length of query: 939
length of database: 18,247,518
effective HSP length: 112
effective length of query: 827
effective length of database: 14,006,526
effective search space: 11583397002
effective search space used: 11583397002
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.