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Search of human proteins with 28872792
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|28872792 CDK5 regulatory subunit associated protein 3 [Homo
sapiens]
(506 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|28872792 CDK5 regulatory subunit associated protein 3 [Homo s... 991 0.0
gi|5031937 calcium binding and coiled-coil domain 2 [Homo sapiens] 40 0.007
gi|189027048 ecto-NOX disulfide-thiol exchanger 1 [Homo sapiens] 38 0.019
gi|189027046 ecto-NOX disulfide-thiol exchanger 1 [Homo sapiens] 38 0.019
gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens] 37 0.055
gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens] 35 0.12
gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens] 35 0.12
gi|157837985 kazrin isoform E [Homo sapiens] 35 0.16
gi|65301128 kazrin isoform C [Homo sapiens] 35 0.16
gi|65301130 kazrin isoform B [Homo sapiens] 35 0.16
gi|63999741 kazrin isoform C [Homo sapiens] 35 0.16
gi|63147424 kazrin isoform A [Homo sapiens] 35 0.16
gi|156104908 myosin heavy chain 6 [Homo sapiens] 35 0.16
gi|221139761 zinc finger protein 853 [Homo sapiens] 35 0.21
gi|21389505 janus kinase and microtubule interacting protein 1 i... 35 0.21
gi|150456473 janus kinase and microtubule interacting protein 1 ... 35 0.21
gi|223029422 SKI-like isoform 3 [Homo sapiens] 34 0.36
gi|223029420 SKI-like isoform 2 [Homo sapiens] 34 0.36
gi|223029418 SKI-like isoform 1 [Homo sapiens] 34 0.36
gi|71061468 centromere protein E [Homo sapiens] 34 0.36
gi|55770834 centromere protein F [Homo sapiens] 34 0.36
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 33 0.47
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 33 0.47
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 33 0.47
gi|125628636 keratin 80 isoform a [Homo sapiens] 33 0.47
gi|125628632 keratin 80 isoform b [Homo sapiens] 33 0.47
gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens] 33 0.47
gi|55749678 ninein-like [Homo sapiens] 33 0.47
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 33 0.61
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 33 0.61
>gi|28872792 CDK5 regulatory subunit associated protein 3 [Homo
sapiens]
Length = 506
Score = 991 bits (2561), Expect = 0.0
Identities = 506/506 (100%), Positives = 506/506 (100%)
Query: 1 MEDHQHVPIDIQTSKLLDWLVDRRHCSLKWQSLVLTIREKINAAIQDMPESEEIAQLLSG 60
MEDHQHVPIDIQTSKLLDWLVDRRHCSLKWQSLVLTIREKINAAIQDMPESEEIAQLLSG
Sbjct: 1 MEDHQHVPIDIQTSKLLDWLVDRRHCSLKWQSLVLTIREKINAAIQDMPESEEIAQLLSG 60
Query: 61 SYIHYFHCLRILDLLKGTEASTKNIFGRYSSQRMKDWQEIIALYEKDNTYLVELSSLLVR 120
SYIHYFHCLRILDLLKGTEASTKNIFGRYSSQRMKDWQEIIALYEKDNTYLVELSSLLVR
Sbjct: 61 SYIHYFHCLRILDLLKGTEASTKNIFGRYSSQRMKDWQEIIALYEKDNTYLVELSSLLVR 120
Query: 121 NVNYEIPSLKKQIAKCQQLQQEYSRKEEECQAGAAEMREQFYHSCKQYGITGENVRGELL 180
NVNYEIPSLKKQIAKCQQLQQEYSRKEEECQAGAAEMREQFYHSCKQYGITGENVRGELL
Sbjct: 121 NVNYEIPSLKKQIAKCQQLQQEYSRKEEECQAGAAEMREQFYHSCKQYGITGENVRGELL 180
Query: 181 ALVKDLPSQLAEIGAAAQQSLGEAIDVYQASVGFVCESPTEQVLPMLRFVQKRGNSTVYE 240
ALVKDLPSQLAEIGAAAQQSLGEAIDVYQASVGFVCESPTEQVLPMLRFVQKRGNSTVYE
Sbjct: 181 ALVKDLPSQLAEIGAAAQQSLGEAIDVYQASVGFVCESPTEQVLPMLRFVQKRGNSTVYE 240
Query: 241 WRTGTEPSVVERPHLEELPEQVAEDAIDWGDFGVEAVSEGTDSGISAEAAGIDWGIFPES 300
WRTGTEPSVVERPHLEELPEQVAEDAIDWGDFGVEAVSEGTDSGISAEAAGIDWGIFPES
Sbjct: 241 WRTGTEPSVVERPHLEELPEQVAEDAIDWGDFGVEAVSEGTDSGISAEAAGIDWGIFPES 300
Query: 301 DSKDPGGDGIDWGDDAVALQITVLEAGTQAPEGVARGPDALTLLEYTETRNQFLDELMEL 360
DSKDPGGDGIDWGDDAVALQITVLEAGTQAPEGVARGPDALTLLEYTETRNQFLDELMEL
Sbjct: 301 DSKDPGGDGIDWGDDAVALQITVLEAGTQAPEGVARGPDALTLLEYTETRNQFLDELMEL 360
Query: 361 EIFLAQRAVELSEEADVLSVSQFQLAPAILQGQTKEKMVTMVSVLEDLIGKLTSLQLQHL 420
EIFLAQRAVELSEEADVLSVSQFQLAPAILQGQTKEKMVTMVSVLEDLIGKLTSLQLQHL
Sbjct: 361 EIFLAQRAVELSEEADVLSVSQFQLAPAILQGQTKEKMVTMVSVLEDLIGKLTSLQLQHL 420
Query: 421 FMILASPRYVDRVTEFLQQKLKQSQLLALKKELMVQKQQEALEEQAALEPKLDLLLEKTK 480
FMILASPRYVDRVTEFLQQKLKQSQLLALKKELMVQKQQEALEEQAALEPKLDLLLEKTK
Sbjct: 421 FMILASPRYVDRVTEFLQQKLKQSQLLALKKELMVQKQQEALEEQAALEPKLDLLLEKTK 480
Query: 481 ELQKLIEADISKRYSGRPVNLMGTSL 506
ELQKLIEADISKRYSGRPVNLMGTSL
Sbjct: 481 ELQKLIEADISKRYSGRPVNLMGTSL 506
>gi|5031937 calcium binding and coiled-coil domain 2 [Homo sapiens]
Length = 446
Score = 39.7 bits (91), Expect = 0.007
Identities = 43/167 (25%), Positives = 84/167 (50%), Gaps = 19/167 (11%)
Query: 344 LEYTETRNQFLDELMELEIFLAQRAVELSEEADVLSVSQFQLAPAILQGQTKEKMVTMVS 403
L+ E ++ + EL++L+ ++ ++S E + + + QL A L Q KE M +V
Sbjct: 196 LKVKEQKDYWETELLQLK----EQNQKMSSENEKMGIRVDQLQ-AQLSTQEKE-MEKLVQ 249
Query: 404 VLEDLIGKLTSLQLQ--HLFMILASPRYVDRVTEFLQQKLKQSQLLALKKELMVQKQQEA 461
+D +L L+ + HLF+ L R + E +++KQ++ A+K KQQE
Sbjct: 250 GDQDKTEQLEQLKKENDHLFLSLTEQRKDQKKLEQTVEQMKQNETTAMK------KQQEL 303
Query: 462 LEEQAALEPKL---DLLLEKTKELQKLIEA--DISKRYSGRPVNLMG 503
++E L +L +++ + ++ +E D+ KR + R ++ MG
Sbjct: 304 MDENFDLSKRLSENEIICNALQRQKERLEGENDLLKRENSRLLSYMG 350
>gi|189027048 ecto-NOX disulfide-thiol exchanger 1 [Homo sapiens]
Length = 643
Score = 38.1 bits (87), Expect = 0.019
Identities = 24/80 (30%), Positives = 46/80 (57%), Gaps = 4/80 (5%)
Query: 431 DRVTEFLQQKLK--QSQLLALKKELMVQKQQ--EALEEQAALEPKLDLLLEKTKELQKLI 486
D+ +FLQQ ++ Q QLL +++EL +K + +A EEQ+ + L +L E+ K ++L+
Sbjct: 467 DQQLQFLQQTMQGMQQQLLTIQEELNNKKSELEQAKEEQSHTQALLKVLQEQLKGTKELV 526
Query: 487 EADISKRYSGRPVNLMGTSL 506
E + +N++ +L
Sbjct: 527 ETNGHSHEDSNEINVLTVAL 546
>gi|189027046 ecto-NOX disulfide-thiol exchanger 1 [Homo sapiens]
Length = 643
Score = 38.1 bits (87), Expect = 0.019
Identities = 24/80 (30%), Positives = 46/80 (57%), Gaps = 4/80 (5%)
Query: 431 DRVTEFLQQKLK--QSQLLALKKELMVQKQQ--EALEEQAALEPKLDLLLEKTKELQKLI 486
D+ +FLQQ ++ Q QLL +++EL +K + +A EEQ+ + L +L E+ K ++L+
Sbjct: 467 DQQLQFLQQTMQGMQQQLLTIQEELNNKKSELEQAKEEQSHTQALLKVLQEQLKGTKELV 526
Query: 487 EADISKRYSGRPVNLMGTSL 506
E + +N++ +L
Sbjct: 527 ETNGHSHEDSNEINVLTVAL 546
>gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens]
Length = 245
Score = 36.6 bits (83), Expect = 0.055
Identities = 43/182 (23%), Positives = 82/182 (45%), Gaps = 19/182 (10%)
Query: 310 IDWGDDAVALQITVLEAGTQAPEGVARGPDALTLLEYTETRNQFLDELMELEIFLAQRAV 369
+D + +A + LE +A + RG ++ E+R Q +E ME++ + A
Sbjct: 63 LDRAQERLATALQKLEEAEKAADESERG------MKVIESRAQKDEEKMEIQEIQLKEAK 116
Query: 370 ELSEEAD--------VLSVSQFQLAPAILQGQTKE-KMVTMVSVLEDLIGKLTSLQLQHL 420
++E+AD L + + L A + + E K + L+ + L SL+ Q
Sbjct: 117 HIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAE 176
Query: 421 FMILASPRYVDRVTEFLQQKLKQSQLLALKKELMVQKQQEALEEQAALEPKLDLLLEKTK 480
RY + + + L KLK+++ A E V K ++++++ LE +L LE+ +
Sbjct: 177 KYSQKEDRYEEEI-KVLSDKLKEAETRAEFAERSVTKLEKSIDD---LEDQLYQQLEQNR 232
Query: 481 EL 482
L
Sbjct: 233 RL 234
>gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens]
Length = 284
Score = 35.4 bits (80), Expect = 0.12
Identities = 41/187 (21%), Positives = 84/187 (44%), Gaps = 19/187 (10%)
Query: 310 IDWGDDAVALQITVLEAGTQAPEGVARGPDALTLLEYTETRNQFLDELMELEIFLAQRAV 369
+D + +A + LE +A + RG ++ E+R Q +E ME++ + A
Sbjct: 99 LDRAQERLATALQKLEEAEKAADESERG------MKVIESRAQKDEEKMEIQEIQLKEAK 152
Query: 370 ELSEEAD--------VLSVSQFQLAPAILQGQTKE-KMVTMVSVLEDLIGKLTSLQLQHL 420
++E+AD L + + L A + + E K + L+ + L SL+ Q
Sbjct: 153 HIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAE 212
Query: 421 FMILASPRYVDRVTEFLQQKLKQSQLLALKKELMVQKQQEALEEQAALEPKLDLLLEKTK 480
RY + + + L KLK+++ A E V K ++++++ LE K+ E+
Sbjct: 213 KYSQKEDRYEEEI-KVLSDKLKEAETRAEFAERSVTKLEKSIDD---LEEKVAHAKEENL 268
Query: 481 ELQKLIE 487
+ ++++
Sbjct: 269 SMHQMLD 275
>gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens]
Length = 284
Score = 35.4 bits (80), Expect = 0.12
Identities = 41/187 (21%), Positives = 84/187 (44%), Gaps = 19/187 (10%)
Query: 310 IDWGDDAVALQITVLEAGTQAPEGVARGPDALTLLEYTETRNQFLDELMELEIFLAQRAV 369
+D + +A + LE +A + RG ++ E+R Q +E ME++ + A
Sbjct: 99 LDRAQERLATALQKLEEAEKAADESERG------MKVIESRAQKDEEKMEIQEIQLKEAK 152
Query: 370 ELSEEAD--------VLSVSQFQLAPAILQGQTKE-KMVTMVSVLEDLIGKLTSLQLQHL 420
++E+AD L + + L A + + E K + L+ + L SL+ Q
Sbjct: 153 HIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAE 212
Query: 421 FMILASPRYVDRVTEFLQQKLKQSQLLALKKELMVQKQQEALEEQAALEPKLDLLLEKTK 480
RY + + + L KLK+++ A E V K ++++++ LE K+ E+
Sbjct: 213 KYSQKEDRYEEEI-KVLSDKLKEAETRAEFAERSVTKLEKSIDD---LEEKVAHAKEENL 268
Query: 481 ELQKLIE 487
+ ++++
Sbjct: 269 SMHQMLD 275
>gi|157837985 kazrin isoform E [Homo sapiens]
Length = 775
Score = 35.0 bits (79), Expect = 0.16
Identities = 34/147 (23%), Positives = 64/147 (43%), Gaps = 16/147 (10%)
Query: 359 ELEIFLAQRAVELSEEADVLSVSQFQLAPAILQGQTKEKMVTMVSVLEDLIGKLTSLQLQ 418
EL + LAQ+ EL+ + L + + + K + +VS ++ L L S + Q
Sbjct: 119 ELRVQLAQKEQELARAKEALQAMKAD------RKRLKGEKTDLVSQMQQLYATLESREEQ 172
Query: 419 HLFMILASPRYVDRVTEFLQQKLKQSQLLALKKELMVQKQQEALEEQAALEPKLDLLLEK 478
I ++ + ++ K+ LL +K + ++ +EA + AL +LDL +
Sbjct: 173 LRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNR 232
Query: 479 TKELQ----------KLIEADISKRYS 495
KEL+ + D+ KR+S
Sbjct: 233 MKELEAELAMAKQSLATLTKDVPKRHS 259
>gi|65301128 kazrin isoform C [Homo sapiens]
Length = 327
Score = 35.0 bits (79), Expect = 0.16
Identities = 34/147 (23%), Positives = 64/147 (43%), Gaps = 16/147 (10%)
Query: 359 ELEIFLAQRAVELSEEADVLSVSQFQLAPAILQGQTKEKMVTMVSVLEDLIGKLTSLQLQ 418
EL + LAQ+ EL+ + L + + + K + +VS ++ L L S + Q
Sbjct: 25 ELRVQLAQKEQELARAKEALQAMKAD------RKRLKGEKTDLVSQMQQLYATLESREEQ 78
Query: 419 HLFMILASPRYVDRVTEFLQQKLKQSQLLALKKELMVQKQQEALEEQAALEPKLDLLLEK 478
I ++ + ++ K+ LL +K + ++ +EA + AL +LDL +
Sbjct: 79 LRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNR 138
Query: 479 TKELQ----------KLIEADISKRYS 495
KEL+ + D+ KR+S
Sbjct: 139 MKELEAELAMAKQSLATLTKDVPKRHS 165
>gi|65301130 kazrin isoform B [Homo sapiens]
Length = 415
Score = 35.0 bits (79), Expect = 0.16
Identities = 34/147 (23%), Positives = 64/147 (43%), Gaps = 16/147 (10%)
Query: 359 ELEIFLAQRAVELSEEADVLSVSQFQLAPAILQGQTKEKMVTMVSVLEDLIGKLTSLQLQ 418
EL + LAQ+ EL+ + L + + + K + +VS ++ L L S + Q
Sbjct: 113 ELRVQLAQKEQELARAKEALQAMKAD------RKRLKGEKTDLVSQMQQLYATLESREEQ 166
Query: 419 HLFMILASPRYVDRVTEFLQQKLKQSQLLALKKELMVQKQQEALEEQAALEPKLDLLLEK 478
I ++ + ++ K+ LL +K + ++ +EA + AL +LDL +
Sbjct: 167 LRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNR 226
Query: 479 TKELQ----------KLIEADISKRYS 495
KEL+ + D+ KR+S
Sbjct: 227 MKELEAELAMAKQSLATLTKDVPKRHS 253
>gi|63999741 kazrin isoform C [Homo sapiens]
Length = 327
Score = 35.0 bits (79), Expect = 0.16
Identities = 34/147 (23%), Positives = 64/147 (43%), Gaps = 16/147 (10%)
Query: 359 ELEIFLAQRAVELSEEADVLSVSQFQLAPAILQGQTKEKMVTMVSVLEDLIGKLTSLQLQ 418
EL + LAQ+ EL+ + L + + + K + +VS ++ L L S + Q
Sbjct: 25 ELRVQLAQKEQELARAKEALQAMKAD------RKRLKGEKTDLVSQMQQLYATLESREEQ 78
Query: 419 HLFMILASPRYVDRVTEFLQQKLKQSQLLALKKELMVQKQQEALEEQAALEPKLDLLLEK 478
I ++ + ++ K+ LL +K + ++ +EA + AL +LDL +
Sbjct: 79 LRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNR 138
Query: 479 TKELQ----------KLIEADISKRYS 495
KEL+ + D+ KR+S
Sbjct: 139 MKELEAELAMAKQSLATLTKDVPKRHS 165
>gi|63147424 kazrin isoform A [Homo sapiens]
Length = 421
Score = 35.0 bits (79), Expect = 0.16
Identities = 34/147 (23%), Positives = 64/147 (43%), Gaps = 16/147 (10%)
Query: 359 ELEIFLAQRAVELSEEADVLSVSQFQLAPAILQGQTKEKMVTMVSVLEDLIGKLTSLQLQ 418
EL + LAQ+ EL+ + L + + + K + +VS ++ L L S + Q
Sbjct: 119 ELRVQLAQKEQELARAKEALQAMKAD------RKRLKGEKTDLVSQMQQLYATLESREEQ 172
Query: 419 HLFMILASPRYVDRVTEFLQQKLKQSQLLALKKELMVQKQQEALEEQAALEPKLDLLLEK 478
I ++ + ++ K+ LL +K + ++ +EA + AL +LDL +
Sbjct: 173 LRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNR 232
Query: 479 TKELQ----------KLIEADISKRYS 495
KEL+ + D+ KR+S
Sbjct: 233 MKELEAELAMAKQSLATLTKDVPKRHS 259
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 35.0 bits (79), Expect = 0.16
Identities = 38/164 (23%), Positives = 75/164 (45%), Gaps = 10/164 (6%)
Query: 120 RNVNYEIPSLKKQIAKCQQLQQEYSRKEEECQAGAAEMREQFYHSCKQYGITGENVRGEL 179
R + + + ++ + Q+ +++ + + Q E+ Q ++ + + RG+L
Sbjct: 1252 RTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLE---EKEALISQLTRGKL 1308
Query: 180 --LALVKDLPSQLAEIGAAAQQSLGEAIDVYQASVGFVCESPTEQVLPM--LRFVQKRGN 235
++DL QL E G A + +L A+ + + E E+ L+ V + N
Sbjct: 1309 SYTQQMEDLKRQLEEEGKA-KNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKAN 1367
Query: 236 STVYEWRTGTEPSVVER-PHLEELPEQVAEDAIDWGDFGVEAVS 278
S V +WRT E ++R LEE +++A+ D + VEAV+
Sbjct: 1368 SEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQD-AEEAVEAVN 1410
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 34.7 bits (78), Expect = 0.21
Identities = 30/117 (25%), Positives = 57/117 (48%), Gaps = 11/117 (9%)
Query: 370 ELSEEADVLSVSQFQLAPAILQGQTKEKMVTMVSVLEDLIGKLTSLQLQHLFMILASPRY 429
+L ++ + L QFQ LQ Q + ++ L+ + + QLQ +
Sbjct: 215 QLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQ--------QL 266
Query: 430 VDRVTEFLQQKL---KQSQLLALKKELMVQKQQEALEEQAALEPKLDLLLEKTKELQ 483
+++ LQQ+L +Q QL +++ ++Q+QQE L++Q P L+ E+ EL+
Sbjct: 267 LEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELE 323
Score = 30.8 bits (68), Expect = 3.0
Identities = 32/143 (22%), Positives = 65/143 (45%), Gaps = 15/143 (10%)
Query: 352 QFLDELMELEIFLAQRAVELSEEADVLSVSQFQLAPAILQGQTKEKMVTMVSVLEDLIGK 411
Q + + +L+ Q L ++ + L Q Q + Q + ++ V +L+ +
Sbjct: 151 QLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQ 210
Query: 412 LTSLQLQHLFMILASPRYVDRVTEFLQQKLKQSQLL-------ALKKELMVQKQ---QEA 461
L QL L ++ + Q++L+Q Q L L+++L+ Q+Q Q+
Sbjct: 211 LQQQQLLQQQEQLQQQQFQQQ-----QEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQ 265
Query: 462 LEEQAALEPKLDLLLEKTKELQK 484
L EQ + + LLL++ ++LQ+
Sbjct: 266 LLEQQQAQLQQQLLLQQQEQLQQ 288
>gi|21389505 janus kinase and microtubule interacting protein 1
isoform 2 [Homo sapiens]
Length = 626
Score = 34.7 bits (78), Expect = 0.21
Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 18/83 (21%)
Query: 406 EDLIGKLTSLQLQHLFMILASPRYVDRVTEFLQQKLKQSQLLALKKELMVQKQQEALEEQ 465
E+L KLTS+Q+ EF Q+K K +L +E ++++QE
Sbjct: 24 EELRAKLTSIQI-----------------EFQQEKSKVGKLRERLQEAKLEREQEQRRHT 66
Query: 466 AAL-EPKLDLLLEKTKELQKLIE 487
A + E K L EKTKELQ L E
Sbjct: 67 AYISELKAKLHEEKTKELQALRE 89
>gi|150456473 janus kinase and microtubule interacting protein 1
isoform 1 [Homo sapiens]
Length = 831
Score = 34.7 bits (78), Expect = 0.21
Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 18/83 (21%)
Query: 406 EDLIGKLTSLQLQHLFMILASPRYVDRVTEFLQQKLKQSQLLALKKELMVQKQQEALEEQ 465
E+L KLTS+Q+ EF Q+K K +L +E ++++QE
Sbjct: 24 EELRAKLTSIQI-----------------EFQQEKSKVGKLRERLQEAKLEREQEQRRHT 66
Query: 466 AAL-EPKLDLLLEKTKELQKLIE 487
A + E K L EKTKELQ L E
Sbjct: 67 AYISELKAKLHEEKTKELQALRE 89
>gi|223029422 SKI-like isoform 3 [Homo sapiens]
Length = 664
Score = 33.9 bits (76), Expect = 0.36
Identities = 25/86 (29%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
Query: 416 QLQHLFMILASPRYVDRVTEFLQQKLKQSQLLALKKELMVQKQQEALEEQAALEPKLDLL 475
QLQ +L+S + + +TE +Q+ Q +L +L+ E Q+ +E EQ LE KL+ +
Sbjct: 534 QLQMEVKMLSSSKSMKELTE--EQQNLQKELESLQNE-HAQRMEEFYVEQKDLEKKLEQI 590
Query: 476 LEKTKELQKLIEADISKRYSGRPVNL 501
+++ +E D Y+G+ L
Sbjct: 591 MKQKCTCDSNLEKDKEAEYAGQLAEL 616
>gi|223029420 SKI-like isoform 2 [Homo sapiens]
Length = 638
Score = 33.9 bits (76), Expect = 0.36
Identities = 25/86 (29%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
Query: 416 QLQHLFMILASPRYVDRVTEFLQQKLKQSQLLALKKELMVQKQQEALEEQAALEPKLDLL 475
QLQ +L+S + + +TE +Q+ Q +L +L+ E Q+ +E EQ LE KL+ +
Sbjct: 508 QLQMEVKMLSSSKSMKELTE--EQQNLQKELESLQNE-HAQRMEEFYVEQKDLEKKLEQI 564
Query: 476 LEKTKELQKLIEADISKRYSGRPVNL 501
+++ +E D Y+G+ L
Sbjct: 565 MKQKCTCDSNLEKDKEAEYAGQLAEL 590
>gi|223029418 SKI-like isoform 1 [Homo sapiens]
Length = 684
Score = 33.9 bits (76), Expect = 0.36
Identities = 25/86 (29%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
Query: 416 QLQHLFMILASPRYVDRVTEFLQQKLKQSQLLALKKELMVQKQQEALEEQAALEPKLDLL 475
QLQ +L+S + + +TE +Q+ Q +L +L+ E Q+ +E EQ LE KL+ +
Sbjct: 554 QLQMEVKMLSSSKSMKELTE--EQQNLQKELESLQNE-HAQRMEEFYVEQKDLEKKLEQI 610
Query: 476 LEKTKELQKLIEADISKRYSGRPVNL 501
+++ +E D Y+G+ L
Sbjct: 611 MKQKCTCDSNLEKDKEAEYAGQLAEL 636
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 33.9 bits (76), Expect = 0.36
Identities = 31/142 (21%), Positives = 67/142 (47%), Gaps = 6/142 (4%)
Query: 355 DELMELEIFLAQRAVELSEEADVLSVSQFQLAPAILQGQTKEKM--VTMVSVLEDLIGKL 412
+ + EL + L+++ E+S L +L I + KE+ + +S +++ + +L
Sbjct: 1491 ETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNEL 1550
Query: 413 TSLQLQHLFMILASPRYVDRVTEFLQQKLKQSQLLALKKELMVQKQQEALEEQAALEPKL 472
+ A ++ E L +L++SQ + ++M+++++E Q AL+ +
Sbjct: 1551 KQFKEHRKAKDSALQSIESKMLE-LTNRLQESQE---EIQIMIKEKEEMKRVQEALQIER 1606
Query: 473 DLLLEKTKELQKLIEADISKRY 494
D L E TKE+ ++ K Y
Sbjct: 1607 DQLKENTKEIVAKMKESQEKEY 1628
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 33.9 bits (76), Expect = 0.36
Identities = 83/431 (19%), Positives = 163/431 (37%), Gaps = 66/431 (15%)
Query: 79 EASTKNIFGRYSSQRMKDWQEIIALYEKDNTYLVELSSL--LVRNV----------NYEI 126
+A +N+ + ++ Q + L E N Y+V SS+ L++ V + EI
Sbjct: 2465 KAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEI 2524
Query: 127 PSLKKQIAKCQQLQQEYSRKEEECQAGAAEMREQFYHSCKQYGITGENVRGELLALVKDL 186
LK QI +QL + S+ E E Q K+ + N+ EL ++ L
Sbjct: 2525 SRLKNQIQDQEQLVSKLSQVEGEHQLW------------KEQNLELRNLTVELEQKIQVL 2572
Query: 187 PSQLAEIGAAAQQSLGEAIDVYQASVGFVCESPTEQVLPMLRFVQKRGNSTVYEWRTGTE 246
S+ A SL + ++V Q+S + + + FV+K T E E
Sbjct: 2573 QSKNA--------SLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQRE 2624
Query: 247 PSVVERPHLEELPEQVAEDAIDWGDFGVEAVSEGTDSGISAEAAGIDWGIFPESDSKDPG 306
+ E+ ++ AE + SG AG + E S
Sbjct: 2625 --------MHEMAQKTAE-------------LQEELSGEKNRLAGELQLLLEEIKSSKDQ 2663
Query: 307 GDGIDWGDDAVALQITVLEAGTQAPEGVARGPDALTLLEYTETRNQ----FLDELMELEI 362
+ + + + + EG R A L E + LD + E+
Sbjct: 2664 LKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEV 2723
Query: 363 FLAQRAVELSEEADVLSVSQFQLAPAILQGQTKEKMVTMVSVLEDLIGKLTSLQLQHLFM 422
+ +L+ + + LS + ++ L +KE++ + ++ +L ++ +L
Sbjct: 2724 EIQTYREKLTSKEECLSSQKLEID---LLKSSKEELNNSLKATTQILEELKKTKMDNLKY 2780
Query: 423 ILASPRYVDRVTEFLQQKLKQSQLLALKKELM------VQKQQEALEEQAALEPKLDLLL 476
+ + +R ++ +K + L +KE++ +Q QE + ++ K+D L
Sbjct: 2781 VNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELT 2840
Query: 477 EKTKELQKLIE 487
+ KEL++ +E
Sbjct: 2841 TEIKELKETLE 2851
Score = 32.7 bits (73), Expect = 0.80
Identities = 35/144 (24%), Positives = 69/144 (47%), Gaps = 19/144 (13%)
Query: 354 LDELMELEIFLAQRAVELSEEADVLSVSQFQLAPAILQGQTKEKMVTMVSVLEDLIGKLT 413
+++ EL++ L + VEL E+ VL+ + +L Q ++ T + LE + KLT
Sbjct: 312 VNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQ---YDQASTKYTALEQKLKKLT 368
Query: 414 ---SLQLQHLFMILASPRYVDRVTEFLQQKLKQSQLLALKKELMVQKQQEALEEQAALEP 470
S Q Q+ S L+QK+K+ + ++EL Q++ +Q ++
Sbjct: 369 EDLSCQRQNAESARCS----------LEQKIKEKE-KEFQEELSRQQRSFQTLDQECIQM 417
Query: 471 KLDLL--LEKTKELQKLIEADISK 492
K L L++ K + +++A++ K
Sbjct: 418 KARLTQELQQAKNMHNVLQAELDK 441
Score = 31.6 bits (70), Expect = 1.8
Identities = 28/148 (18%), Positives = 69/148 (46%), Gaps = 9/148 (6%)
Query: 341 LTLLEYTETRNQFLDELMELEIFLAQRAVELSEEADVLSVSQFQLAPAILQGQTKEKMVT 400
L + E + R + D L + ++ +R +++SEE L + + +K ++ T
Sbjct: 2136 LHIAEKLKERERENDSLKD-KVENLERELQMSEENQELVILDAE--------NSKAEVET 2186
Query: 401 MVSVLEDLIGKLTSLQLQHLFMILASPRYVDRVTEFLQQKLKQSQLLALKKELMVQKQQE 460
+ + +E++ L +L + + ++ E Q + +LL+ K L+ +K+Q
Sbjct: 2187 LKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQA 2246
Query: 461 ALEEQAALEPKLDLLLEKTKELQKLIEA 488
++ + + +++L + KEL + + A
Sbjct: 2247 EIQIKEESKTAVEMLQNQLKELNEAVAA 2274
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 33.5 bits (75), Expect = 0.47
Identities = 28/146 (19%), Positives = 64/146 (43%), Gaps = 19/146 (13%)
Query: 69 LRILDLLKGTEASTKNIFGRYSSQRMKDWQEIIALYEKDNTYLVELSS------------ 116
L++ D++ +A+ + R + Q+ + Q + + +++ ++L
Sbjct: 809 LKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKP 868
Query: 117 -LLVRNVNYEIPSLKKQIAKCQQLQQEYSRKEEECQAGAAEMREQFYHSCKQYG------ 169
L V + + + +++ K Q+LQQ+ +R+ E Q A++ E+ +Q
Sbjct: 869 LLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELC 928
Query: 170 ITGENVRGELLALVKDLPSQLAEIGA 195
E RG L A ++L ++E+ A
Sbjct: 929 AEAEETRGRLAARKQELELVVSELEA 954
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 33.5 bits (75), Expect = 0.47
Identities = 28/146 (19%), Positives = 64/146 (43%), Gaps = 19/146 (13%)
Query: 69 LRILDLLKGTEASTKNIFGRYSSQRMKDWQEIIALYEKDNTYLVELSS------------ 116
L++ D++ +A+ + R + Q+ + Q + + +++ ++L
Sbjct: 801 LKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKP 860
Query: 117 -LLVRNVNYEIPSLKKQIAKCQQLQQEYSRKEEECQAGAAEMREQFYHSCKQYG------ 169
L V + + + +++ K Q+LQQ+ +R+ E Q A++ E+ +Q
Sbjct: 861 LLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELC 920
Query: 170 ITGENVRGELLALVKDLPSQLAEIGA 195
E RG L A ++L ++E+ A
Sbjct: 921 AEAEETRGRLAARKQELELVVSELEA 946
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 33.5 bits (75), Expect = 0.47
Identities = 28/146 (19%), Positives = 64/146 (43%), Gaps = 19/146 (13%)
Query: 69 LRILDLLKGTEASTKNIFGRYSSQRMKDWQEIIALYEKDNTYLVELSS------------ 116
L++ D++ +A+ + R + Q+ + Q + + +++ ++L
Sbjct: 842 LKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKP 901
Query: 117 -LLVRNVNYEIPSLKKQIAKCQQLQQEYSRKEEECQAGAAEMREQFYHSCKQYG------ 169
L V + + + +++ K Q+LQQ+ +R+ E Q A++ E+ +Q
Sbjct: 902 LLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELC 961
Query: 170 ITGENVRGELLALVKDLPSQLAEIGA 195
E RG L A ++L ++E+ A
Sbjct: 962 AEAEETRGRLAARKQELELVVSELEA 987
>gi|125628636 keratin 80 isoform a [Homo sapiens]
Length = 452
Score = 33.5 bits (75), Expect = 0.47
Identities = 35/116 (30%), Positives = 57/116 (49%), Gaps = 14/116 (12%)
Query: 384 QLAPAI--LQGQTKEKMVTMVSVLEDLIGKLTSLQLQHLFMILASPRYVDRVTEFLQ-QK 440
+L PA+ L+ Q KE+M + LIGK+ +L+ ++ + ++ FLQ Q
Sbjct: 71 KLDPAVQQLKNQEKEEMKALNDKFASLIGKVQALEQRN--------QLLETRWSFLQGQD 122
Query: 441 LKQSQLLALKKELMVQKQQE---ALEEQAALEPKLDLLLEKTKELQKLIEADISKR 493
L L +E + Q+E +E+ LE L +LEK +E + E +ISKR
Sbjct: 123 SAIFDLGHLYEEYQGRLQEELRKVSQERGQLEANLLQVLEKVEEFRIRYEDEISKR 178
>gi|125628632 keratin 80 isoform b [Homo sapiens]
Length = 422
Score = 33.5 bits (75), Expect = 0.47
Identities = 35/116 (30%), Positives = 57/116 (49%), Gaps = 14/116 (12%)
Query: 384 QLAPAI--LQGQTKEKMVTMVSVLEDLIGKLTSLQLQHLFMILASPRYVDRVTEFLQ-QK 440
+L PA+ L+ Q KE+M + LIGK+ +L+ ++ + ++ FLQ Q
Sbjct: 71 KLDPAVQQLKNQEKEEMKALNDKFASLIGKVQALEQRN--------QLLETRWSFLQGQD 122
Query: 441 LKQSQLLALKKELMVQKQQE---ALEEQAALEPKLDLLLEKTKELQKLIEADISKR 493
L L +E + Q+E +E+ LE L +LEK +E + E +ISKR
Sbjct: 123 SAIFDLGHLYEEYQGRLQEELRKVSQERGQLEANLLQVLEKVEEFRIRYEDEISKR 178
>gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens]
Length = 284
Score = 33.5 bits (75), Expect = 0.47
Identities = 37/164 (22%), Positives = 73/164 (44%), Gaps = 16/164 (9%)
Query: 310 IDWGDDAVALQITVLEAGTQAPEGVARGPDALTLLEYTETRNQFLDELMELEIFLAQRAV 369
+D + +A + LE +A + RG ++ E+R Q +E ME++ + A
Sbjct: 99 LDRAQERLATALQKLEEAEKAADESERG------MKVIESRAQKDEEKMEIQEIQLKEAK 152
Query: 370 ELSEEAD--------VLSVSQFQLAPAILQGQTKE-KMVTMVSVLEDLIGKLTSLQLQHL 420
++E+AD L + + L A + + E K + L+ + L SL+ Q
Sbjct: 153 HIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAE 212
Query: 421 FMILASPRYVDRVTEFLQQKLKQSQLLALKKELMVQKQQEALEE 464
RY + + + L KLK+++ A E V K ++++++
Sbjct: 213 KYSQKEDRYEEEI-KVLSDKLKEAETRAEFAERSVTKLEKSIDD 255
>gi|55749678 ninein-like [Homo sapiens]
Length = 1382
Score = 33.5 bits (75), Expect = 0.47
Identities = 38/191 (19%), Positives = 85/191 (44%), Gaps = 25/191 (13%)
Query: 311 DWGDDAVALQITVLEAGTQAPEGVARGPD--------ALTLLEYTETRNQFLDELMELEI 362
++ D L + VL+ G +A A+ + +L E + Q D++ +L +
Sbjct: 1144 NYKDQLSQLNVRVLQLGQEASTHQAQNEEHRVTIQMLTQSLEEVVRSGQQQSDQIQKLRV 1203
Query: 363 FL--------------AQRAVELSEEADVLSVSQFQLAPAILQGQTKEKMVTMVSVLEDL 408
L ++ L E D + + +L A Q + ++V V E
Sbjct: 1204 ELECLNQEHQSLQLPWSELTQTLEESQDQVQGAHLRLRQAQAQHLQEVRLVPQDRVAE-- 1261
Query: 409 IGKLTSLQLQHLFMILASPRYV-DRVTEFLQQKLKQSQLLALKKELMVQKQQEALEEQAA 467
+ +L SLQ + L + R ++ + ++++++++++ E+++Q++ + L+EQ
Sbjct: 1262 LHRLLSLQGEQARRRLDAQREEHEKQLKATEERVEEAEMILKNMEMLLQEKVDKLKEQFE 1321
Query: 468 LEPKLDLLLEK 478
K DLLL++
Sbjct: 1322 KNTKSDLLLKE 1332
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 33.1 bits (74), Expect = 0.61
Identities = 39/147 (26%), Positives = 70/147 (47%), Gaps = 16/147 (10%)
Query: 348 ETRNQFLDELMELEIFLAQRAVELSEEADVLSVSQFQLAPAILQGQTKEKMVTMVSVLED 407
+ + QF E+++ +I Q+ VE E+ VSQ QL + + T+ S E
Sbjct: 2526 QEQGQFETEMLQKKIVNLQKIVE--EKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPER 2583
Query: 408 L-IGKLTSLQLQHLFMILASPRYVDRVTEFLQQKLKQSQLLALKKELMVQKQQEALEEQA 466
I L L+ L +++ R++E +SQ++ + L+++K+Q + E+
Sbjct: 2584 TNIQNLNQLREDELGSDISALTL--RISEL------ESQVVEMHTSLILEKEQVEIAEKN 2635
Query: 467 ALEPKLDLLLEKTKELQKLIEADISKR 493
LE + LL ELQKL+E + K+
Sbjct: 2636 VLEKEKKLL-----ELQKLLEGNEKKQ 2657
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 33.1 bits (74), Expect = 0.61
Identities = 39/147 (26%), Positives = 70/147 (47%), Gaps = 16/147 (10%)
Query: 348 ETRNQFLDELMELEIFLAQRAVELSEEADVLSVSQFQLAPAILQGQTKEKMVTMVSVLED 407
+ + QF E+++ +I Q+ VE E+ VSQ QL + + T+ S E
Sbjct: 2518 QEQGQFETEMLQKKIVNLQKIVE--EKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPER 2575
Query: 408 L-IGKLTSLQLQHLFMILASPRYVDRVTEFLQQKLKQSQLLALKKELMVQKQQEALEEQA 466
I L L+ L +++ R++E +SQ++ + L+++K+Q + E+
Sbjct: 2576 TNIQNLNQLREDELGSDISALTL--RISEL------ESQVVEMHTSLILEKEQVEIAEKN 2627
Query: 467 ALEPKLDLLLEKTKELQKLIEADISKR 493
LE + LL ELQKL+E + K+
Sbjct: 2628 VLEKEKKLL-----ELQKLLEGNEKKQ 2649
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,761,822
Number of Sequences: 37866
Number of extensions: 787334
Number of successful extensions: 3818
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 138
Number of HSP's that attempted gapping in prelim test: 3605
Number of HSP's gapped (non-prelim): 377
length of query: 506
length of database: 18,247,518
effective HSP length: 107
effective length of query: 399
effective length of database: 14,195,856
effective search space: 5664146544
effective search space used: 5664146544
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.