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Search of human proteins with 28872765
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|28872765 proteasome 26S non-ATPase subunit 12 isoform 2
[Homo sapiens]
(436 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|28872765 proteasome 26S non-ATPase subunit 12 isoform 2 [Homo... 854 0.0
gi|4506221 proteasome 26S non-ATPase subunit 12 isoform 1 [Homo ... 842 0.0
gi|38373690 COP9 signalosome subunit 4 [Homo sapiens] 84 3e-16
gi|219842262 COP9 constitutive photomorphogenic homolog subunit ... 41 0.002
gi|4759264 COP9 constitutive photomorphogenic homolog subunit 2 ... 41 0.002
gi|22208850 Golgi coiled-coil protein 1 [Homo sapiens] 37 0.046
gi|51479166 bicaudal D homolog 2 isoform 1 [Homo sapiens] 36 0.060
gi|21735417 bicaudal D homolog 2 isoform 2 [Homo sapiens] 36 0.060
gi|156104908 myosin heavy chain 6 [Homo sapiens] 36 0.078
gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi... 35 0.17
gi|115511012 coiled-coil domain containing 136 [Homo sapiens] 35 0.17
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 35 0.17
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 34 0.23
gi|187761324 shootin1 isoform a [Homo sapiens] 34 0.23
gi|50511340 shootin1 isoform b [Homo sapiens] 34 0.23
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 33 0.39
gi|64085252 hypothetical protein LOC145508 [Homo sapiens] 33 0.51
gi|154426264 ubiquitin protein ligase E3 component n-recognin 7 ... 33 0.66
gi|154426322 ubiquitin protein ligase E3 component n-recognin 7 ... 33 0.66
gi|23238222 COP9 constitutive photomorphogenic homolog subunit 3... 33 0.66
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 33 0.66
gi|7661914 proteasome (prosome, macropain) 26S subunit, non-ATPa... 32 0.87
gi|219689136 coiled-coil domain containing 68 [Homo sapiens] 32 1.5
gi|13376818 coiled-coil domain containing 68 [Homo sapiens] 32 1.5
gi|118498362 kinectin 1 isoform b [Homo sapiens] 32 1.5
gi|23397429 eukaryotic translation initiation factor 3, subunit ... 32 1.5
gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1 ... 32 1.5
gi|63999048 syntaxin binding protein 4 [Homo sapiens] 32 1.5
gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1 ... 32 1.5
gi|28269672 serologically defined colon cancer antigen 8 [Homo s... 31 1.9
>gi|28872765 proteasome 26S non-ATPase subunit 12 isoform 2 [Homo
sapiens]
Length = 436
Score = 854 bits (2207), Expect = 0.0
Identities = 436/436 (100%), Positives = 436/436 (100%)
Query: 1 MADGGSERADGRIVKMEVDYSATVDQRLPECAKLAKASDMVSTSRILVAVVKMCYEAKEW 60
MADGGSERADGRIVKMEVDYSATVDQRLPECAKLAKASDMVSTSRILVAVVKMCYEAKEW
Sbjct: 1 MADGGSERADGRIVKMEVDYSATVDQRLPECAKLAKASDMVSTSRILVAVVKMCYEAKEW 60
Query: 61 DLLNENIMLLSKRRSQLKQAVAKMVQQCCTYVEEITDLPIKLRLIDTLRMVTEGKIYVEI 120
DLLNENIMLLSKRRSQLKQAVAKMVQQCCTYVEEITDLPIKLRLIDTLRMVTEGKIYVEI
Sbjct: 61 DLLNENIMLLSKRRSQLKQAVAKMVQQCCTYVEEITDLPIKLRLIDTLRMVTEGKIYVEI 120
Query: 121 ERARLTKTLATIKEQNGDVKEAASILQELQVETYGSMEKKERVEFILEQMRLCLAVKDYI 180
ERARLTKTLATIKEQNGDVKEAASILQELQVETYGSMEKKERVEFILEQMRLCLAVKDYI
Sbjct: 121 ERARLTKTLATIKEQNGDVKEAASILQELQVETYGSMEKKERVEFILEQMRLCLAVKDYI 180
Query: 181 RTQIISKKINTKFFQEENTEKLKLKYYNLMIQLDQHEGSYLSICKHYRAIYDTPCIQAES 240
RTQIISKKINTKFFQEENTEKLKLKYYNLMIQLDQHEGSYLSICKHYRAIYDTPCIQAES
Sbjct: 181 RTQIISKKINTKFFQEENTEKLKLKYYNLMIQLDQHEGSYLSICKHYRAIYDTPCIQAES 240
Query: 241 EKWQQALKSVVLYVILAPFDNEQSDLVHRISGDKKLEEIPKYKDLLKLFTTMELMRWSTL 300
EKWQQALKSVVLYVILAPFDNEQSDLVHRISGDKKLEEIPKYKDLLKLFTTMELMRWSTL
Sbjct: 241 EKWQQALKSVVLYVILAPFDNEQSDLVHRISGDKKLEEIPKYKDLLKLFTTMELMRWSTL 300
Query: 301 VEDYGMELRKGSLESPATDVFGSTEEGEKRWKDLKNRVVEHNIRIMAKYYTRITMKRMAQ 360
VEDYGMELRKGSLESPATDVFGSTEEGEKRWKDLKNRVVEHNIRIMAKYYTRITMKRMAQ
Sbjct: 301 VEDYGMELRKGSLESPATDVFGSTEEGEKRWKDLKNRVVEHNIRIMAKYYTRITMKRMAQ 360
Query: 361 LLDLSVDESEAFLSNLVVNKTIFAKVDRLAGIINFQRPKDPNNLLNDWSQKLNSLMSLVN 420
LLDLSVDESEAFLSNLVVNKTIFAKVDRLAGIINFQRPKDPNNLLNDWSQKLNSLMSLVN
Sbjct: 361 LLDLSVDESEAFLSNLVVNKTIFAKVDRLAGIINFQRPKDPNNLLNDWSQKLNSLMSLVN 420
Query: 421 KTTHLIAKEEMIHNLQ 436
KTTHLIAKEEMIHNLQ
Sbjct: 421 KTTHLIAKEEMIHNLQ 436
>gi|4506221 proteasome 26S non-ATPase subunit 12 isoform 1 [Homo
sapiens]
Length = 456
Score = 842 bits (2176), Expect = 0.0
Identities = 436/456 (95%), Positives = 436/456 (95%), Gaps = 20/456 (4%)
Query: 1 MADGGSERADGRIVKMEVDYSATVDQRLPECAKLAK--------------------ASDM 40
MADGGSERADGRIVKMEVDYSATVDQRLPECAKLAK ASDM
Sbjct: 1 MADGGSERADGRIVKMEVDYSATVDQRLPECAKLAKEGRLQEVIETLLSLEKQTRTASDM 60
Query: 41 VSTSRILVAVVKMCYEAKEWDLLNENIMLLSKRRSQLKQAVAKMVQQCCTYVEEITDLPI 100
VSTSRILVAVVKMCYEAKEWDLLNENIMLLSKRRSQLKQAVAKMVQQCCTYVEEITDLPI
Sbjct: 61 VSTSRILVAVVKMCYEAKEWDLLNENIMLLSKRRSQLKQAVAKMVQQCCTYVEEITDLPI 120
Query: 101 KLRLIDTLRMVTEGKIYVEIERARLTKTLATIKEQNGDVKEAASILQELQVETYGSMEKK 160
KLRLIDTLRMVTEGKIYVEIERARLTKTLATIKEQNGDVKEAASILQELQVETYGSMEKK
Sbjct: 121 KLRLIDTLRMVTEGKIYVEIERARLTKTLATIKEQNGDVKEAASILQELQVETYGSMEKK 180
Query: 161 ERVEFILEQMRLCLAVKDYIRTQIISKKINTKFFQEENTEKLKLKYYNLMIQLDQHEGSY 220
ERVEFILEQMRLCLAVKDYIRTQIISKKINTKFFQEENTEKLKLKYYNLMIQLDQHEGSY
Sbjct: 181 ERVEFILEQMRLCLAVKDYIRTQIISKKINTKFFQEENTEKLKLKYYNLMIQLDQHEGSY 240
Query: 221 LSICKHYRAIYDTPCIQAESEKWQQALKSVVLYVILAPFDNEQSDLVHRISGDKKLEEIP 280
LSICKHYRAIYDTPCIQAESEKWQQALKSVVLYVILAPFDNEQSDLVHRISGDKKLEEIP
Sbjct: 241 LSICKHYRAIYDTPCIQAESEKWQQALKSVVLYVILAPFDNEQSDLVHRISGDKKLEEIP 300
Query: 281 KYKDLLKLFTTMELMRWSTLVEDYGMELRKGSLESPATDVFGSTEEGEKRWKDLKNRVVE 340
KYKDLLKLFTTMELMRWSTLVEDYGMELRKGSLESPATDVFGSTEEGEKRWKDLKNRVVE
Sbjct: 301 KYKDLLKLFTTMELMRWSTLVEDYGMELRKGSLESPATDVFGSTEEGEKRWKDLKNRVVE 360
Query: 341 HNIRIMAKYYTRITMKRMAQLLDLSVDESEAFLSNLVVNKTIFAKVDRLAGIINFQRPKD 400
HNIRIMAKYYTRITMKRMAQLLDLSVDESEAFLSNLVVNKTIFAKVDRLAGIINFQRPKD
Sbjct: 361 HNIRIMAKYYTRITMKRMAQLLDLSVDESEAFLSNLVVNKTIFAKVDRLAGIINFQRPKD 420
Query: 401 PNNLLNDWSQKLNSLMSLVNKTTHLIAKEEMIHNLQ 436
PNNLLNDWSQKLNSLMSLVNKTTHLIAKEEMIHNLQ
Sbjct: 421 PNNLLNDWSQKLNSLMSLVNKTTHLIAKEEMIHNLQ 456
>gi|38373690 COP9 signalosome subunit 4 [Homo sapiens]
Length = 406
Score = 83.6 bits (205), Expect = 3e-16
Identities = 86/370 (23%), Positives = 169/370 (45%), Gaps = 34/370 (9%)
Query: 62 LLNENIMLLSKRRSQLKQAVAKMVQQCCTYVEEITDLPIKLRLIDTLRMVTEGKIYVEIE 121
++NEN+ L+ R+ ++ CT++ + D K TL + I E +
Sbjct: 52 MVNENVSLVISRQ---------LLTDFCTHLPNLPDSTAKEIYHFTLEKIQPRVISFEEQ 102
Query: 122 RARLTKTLATIKEQNGDVKEAASILQELQVETYGSMEKKE-RVEFILEQMRLCLAVKDYI 180
A + + LA+I E+ D + AA +L + +ET + ++E L+ RL L D +
Sbjct: 103 VASIRQHLASIYEKEEDWRNAAQVLVGIPLETGQKQYNVDYKLETYLKIARLYLEDDDPV 162
Query: 181 RTQIISKKINTKFFQEENT-EKLKLKYYNLMIQLDQHEGSYLSICKHYRAI-YDTPCIQA 238
+ + + + Q E+T E+L++ Y ++ + ++ + Y + Y T I
Sbjct: 163 QAEAYINRAS--LLQNESTNEQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKT--IVH 218
Query: 239 ESEKWQQALKSVVLYVILAPFDNEQSDLVHRISGDKKLEEIPKYKDLLKLFTTMELMRWS 298
ESE+ + ALK + ILA ++S ++ + D++ +++ Y L K++ ++R +
Sbjct: 219 ESERLE-ALKHALHCTILASAGQQRSRMLATLFKDERCQQLAAYGILEKMYLD-RIIRGN 276
Query: 299 TLVEDYGMELRKGSLESPATDVFGSTEEGEKRWKDLKNRVVEHNIRIMAKYYTRITMKRM 358
L E M + AT GS+ L V+EHN+ +K Y IT + +
Sbjct: 277 QLQEFAAMLMP----HQKATTADGSSI--------LDRAVIEHNLLSASKLYNNITFEEL 324
Query: 359 AQLLDLSVDESEAFLSNLVVNKTIFAKVDRLAGIINFQRPKDPNNLLNDWSQKLNSLMSL 418
LL++ ++E S ++ + +D++ GI++F + L W +++ SL
Sbjct: 325 GALLEIPAAKAEKIASQMITEGRMNGFIDQIDGIVHF----ETREALPTWDKQIQSLCFQ 380
Query: 419 VNKTTHLIAK 428
VN I++
Sbjct: 381 VNNLLEKISQ 390
>gi|219842262 COP9 constitutive photomorphogenic homolog subunit 2
isoform 2 [Homo sapiens]
Length = 450
Score = 40.8 bits (94), Expect = 0.002
Identities = 56/319 (17%), Positives = 137/319 (42%), Gaps = 49/319 (15%)
Query: 114 GKIYVEIER-ARLTKTLATIKEQ------NGDVKEAASILQ--ELQVETYGSMEKKERVE 164
GK+Y+E E +L K L + + D+K+ +L+ L+++ Y + + ++++
Sbjct: 163 GKLYLEREEYGKLQKILRQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLK 222
Query: 165 FILEQ-MRLCLAVKDYIRTQIISKKINTKFFQEENTEKLKLKYYNLMIQLDQHEGSYLSI 223
+ EQ + + A+ + +I + +E EK ++ D+ +
Sbjct: 223 ALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTT 282
Query: 224 CKHYRAIYDTPCIQAESEKWQQALKSVVLYVILAPFDNEQSDLVHRISGDKKLEEIPKYK 283
C Y L ++++ + PFD++++ K EI
Sbjct: 283 CLKYLV-----------------LANMLMKSGINPFDSQEAKPY------KNDPEILAMT 319
Query: 284 DLLKLFTTMELMRWSTLVEDYGMELRKGSLESPATDVFGSTEEGEKRWKDLKNRVVEHNI 343
+L+ + ++ + +++ + ++ P E E+ ++++ +V+ I
Sbjct: 320 NLVSAYQNNDITEFEKILKTNHSNI----MDDPFI-----REHIEELLRNIRTQVL---I 367
Query: 344 RIMAKYYTRITMKRMAQLLDLSVDESEAFLSNLVVNKTIFAKVDRLAGIINFQRPKDPN- 402
+++ K YTRI + +++ L++ V + E+ L +++ TI ++D++ ++ K
Sbjct: 368 KLI-KPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDHQKRGGA 426
Query: 403 --NLLNDWSQKLNSLMSLV 419
L+ W+ +LNSL V
Sbjct: 427 RYTALDKWTNQLNSLNQAV 445
>gi|4759264 COP9 constitutive photomorphogenic homolog subunit 2
isoform 1 [Homo sapiens]
Length = 443
Score = 40.8 bits (94), Expect = 0.002
Identities = 56/319 (17%), Positives = 137/319 (42%), Gaps = 49/319 (15%)
Query: 114 GKIYVEIER-ARLTKTLATIKEQ------NGDVKEAASILQ--ELQVETYGSMEKKERVE 164
GK+Y+E E +L K L + + D+K+ +L+ L+++ Y + + ++++
Sbjct: 156 GKLYLEREEYGKLQKILRQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLK 215
Query: 165 FILEQ-MRLCLAVKDYIRTQIISKKINTKFFQEENTEKLKLKYYNLMIQLDQHEGSYLSI 223
+ EQ + + A+ + +I + +E EK ++ D+ +
Sbjct: 216 ALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTT 275
Query: 224 CKHYRAIYDTPCIQAESEKWQQALKSVVLYVILAPFDNEQSDLVHRISGDKKLEEIPKYK 283
C Y L ++++ + PFD++++ K EI
Sbjct: 276 CLKYLV-----------------LANMLMKSGINPFDSQEAKPY------KNDPEILAMT 312
Query: 284 DLLKLFTTMELMRWSTLVEDYGMELRKGSLESPATDVFGSTEEGEKRWKDLKNRVVEHNI 343
+L+ + ++ + +++ + ++ P E E+ ++++ +V+ I
Sbjct: 313 NLVSAYQNNDITEFEKILKTNHSNI----MDDPFI-----REHIEELLRNIRTQVL---I 360
Query: 344 RIMAKYYTRITMKRMAQLLDLSVDESEAFLSNLVVNKTIFAKVDRLAGIINFQRPKDPN- 402
+++ K YTRI + +++ L++ V + E+ L +++ TI ++D++ ++ K
Sbjct: 361 KLI-KPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDHQKRGGA 419
Query: 403 --NLLNDWSQKLNSLMSLV 419
L+ W+ +LNSL V
Sbjct: 420 RYTALDKWTNQLNSLNQAV 438
>gi|22208850 Golgi coiled-coil protein 1 [Homo sapiens]
Length = 775
Score = 36.6 bits (83), Expect = 0.046
Identities = 40/152 (26%), Positives = 65/152 (42%), Gaps = 20/152 (13%)
Query: 70 LSKRRSQLKQAVAKMVQQCCTYVEEITDLPIKLRLIDTLRM---VTEGKIYVEIERARLT 126
+ KR QLK +A + T +E + + L D +M + + E ERARL
Sbjct: 154 VDKRLHQLKTQLATLTSSLATVTQEKSRMEASY-LADKKKMKQDLEDASNKAEEERARLE 212
Query: 127 KTLATIKEQNGDVK---------------EAASILQELQVETYGSMEKKERVEFILEQMR 171
L ++EQ + K + A +L+ELQ +++ +E LE+ R
Sbjct: 213 GELKGLQEQIAETKARLITQQHDRAQEQSDHALMLRELQKLLQEERTQRQDLELRLEETR 272
Query: 172 LCLAVKDYIRTQIISKKINTKFFQEENTEKLK 203
LA + Y Q+ ++ TK E E+LK
Sbjct: 273 EALAGRAYAAEQMEGFELQTKQLTRE-VEELK 303
>gi|51479166 bicaudal D homolog 2 isoform 1 [Homo sapiens]
Length = 855
Score = 36.2 bits (82), Expect = 0.060
Identities = 73/342 (21%), Positives = 142/342 (41%), Gaps = 43/342 (12%)
Query: 15 KMEVDYSATVDQRLPECAKLAKASDMVSTSRILVAVVKMCYEAKEWDLLNEN-------I 67
++EVDY A E +L +A T+ VA E++E L+ E+ +
Sbjct: 63 ELEVDYEAIRS----EMEQLKEAFGQAHTNHKKVAADG---ESREESLIQESASKEQYYV 115
Query: 68 MLLSKRRSQLKQAVAKMVQQCCTYVEEITDLPIKLRLIDTLRMVTEGKIYVEIER----- 122
+ + +++LKQ + ++ + E + + +L+ I+ + G++ +I+
Sbjct: 116 RKVLELQTELKQ-LRNVLTNTQSENERLASVAQELKEINQNVEIQRGRLRDDIKEYKFRE 174
Query: 123 ARLTKTLATIKEQNGDVKEAASILQELQVETYGSMEK----KERVEFILEQMRLCLAVKD 178
ARL + + ++E+N +++ S+L++ QVE G + +E E++ Q+ + +K+
Sbjct: 175 ARLLQDYSELEEENISLQKQVSVLRQNQVEFEGLKHEIKRLEEETEYLNSQLEDAIRLKE 234
Query: 179 YIRTQIISKKINTKFFQEENTEKLKLKYYNLMIQLDQHEGSYLSICKHYRAIYDTPCIQA 238
Q + + + T + E L+ + + M D S+L + D A
Sbjct: 235 ISERQ-LEEALETLKTEREQKNSLRKELSHYMSINDSFYTSHLHVSLDGLKFSDD---AA 290
Query: 239 ESEKWQQALKSVVLYVILA--PFDNEQS------------DLVHRISGDKKLEEIPKYKD 284
E +AL + + LA P DN+ S LV + + + EI K K
Sbjct: 291 EPNNDAEALVNGFEHGGLAKLPLDNKTSTPKKEGLAPPSPSLVSDLLSELNISEIQKLKQ 350
Query: 285 LLKLFTTMELMRWSTLVE-DYGMELRKGSLESPATDVFGSTE 325
L + +TL + +E +GSL V TE
Sbjct: 351 QLMQMEREKAGLLATLQDTQKQLEHTRGSLSEQQEKVTRLTE 392
>gi|21735417 bicaudal D homolog 2 isoform 2 [Homo sapiens]
Length = 824
Score = 36.2 bits (82), Expect = 0.060
Identities = 73/342 (21%), Positives = 142/342 (41%), Gaps = 43/342 (12%)
Query: 15 KMEVDYSATVDQRLPECAKLAKASDMVSTSRILVAVVKMCYEAKEWDLLNEN-------I 67
++EVDY A E +L +A T+ VA E++E L+ E+ +
Sbjct: 63 ELEVDYEAIRS----EMEQLKEAFGQAHTNHKKVAADG---ESREESLIQESASKEQYYV 115
Query: 68 MLLSKRRSQLKQAVAKMVQQCCTYVEEITDLPIKLRLIDTLRMVTEGKIYVEIER----- 122
+ + +++LKQ + ++ + E + + +L+ I+ + G++ +I+
Sbjct: 116 RKVLELQTELKQ-LRNVLTNTQSENERLASVAQELKEINQNVEIQRGRLRDDIKEYKFRE 174
Query: 123 ARLTKTLATIKEQNGDVKEAASILQELQVETYGSMEK----KERVEFILEQMRLCLAVKD 178
ARL + + ++E+N +++ S+L++ QVE G + +E E++ Q+ + +K+
Sbjct: 175 ARLLQDYSELEEENISLQKQVSVLRQNQVEFEGLKHEIKRLEEETEYLNSQLEDAIRLKE 234
Query: 179 YIRTQIISKKINTKFFQEENTEKLKLKYYNLMIQLDQHEGSYLSICKHYRAIYDTPCIQA 238
Q + + + T + E L+ + + M D S+L + D A
Sbjct: 235 ISERQ-LEEALETLKTEREQKNSLRKELSHYMSINDSFYTSHLHVSLDGLKFSDD---AA 290
Query: 239 ESEKWQQALKSVVLYVILA--PFDNEQS------------DLVHRISGDKKLEEIPKYKD 284
E +AL + + LA P DN+ S LV + + + EI K K
Sbjct: 291 EPNNDAEALVNGFEHGGLAKLPLDNKTSTPKKEGLAPPSPSLVSDLLSELNISEIQKLKQ 350
Query: 285 LLKLFTTMELMRWSTLVE-DYGMELRKGSLESPATDVFGSTE 325
L + +TL + +E +GSL V TE
Sbjct: 351 QLMQMEREKAGLLATLQDTQKQLEHTRGSLSEQQEKVTRLTE 392
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 35.8 bits (81), Expect = 0.078
Identities = 49/220 (22%), Positives = 97/220 (44%), Gaps = 29/220 (13%)
Query: 52 KMCYEAKEWDLLNENIMLLSKRRSQLKQAVAKMVQQCCTYVEEITDLPIKLRLIDTLRMV 111
K+ EAK ++ NE + + ++L K+ +C ++I DL + L ++ +
Sbjct: 914 KIQLEAKVKEM-NERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHA 972
Query: 112 TEGKI-YVEIERARLTKTLATIKEQNGDVKEA-ASILQELQVE----------------- 152
TE K+ + E A L + +A + ++ ++EA L +LQVE
Sbjct: 973 TENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQ 1032
Query: 153 ---TYGSMEKKERVEFILEQMRLCLAVKDYIRTQIISKKINTKFFQEENTEKLKLKYYNL 209
GS+E++++V LE+ + L + + I N K E EKLK K +++
Sbjct: 1033 VDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLE---EKLKKKEFDI 1089
Query: 210 MIQLDQHEGSYLSICKHYRAIYDTPCIQAESEKWQQALKS 249
Q + E + + + + + QA E+ ++ L++
Sbjct: 1090 NQQNSKIEDEQVLALQLQKKLKEN---QARIEELEEELEA 1126
Score = 29.6 bits (65), Expect = 5.6
Identities = 53/243 (21%), Positives = 106/243 (43%), Gaps = 28/243 (11%)
Query: 115 KIYVEIERARLTKTLATIKEQNGDVKEAASILQELQVETYGSMEKKE-RVEFILEQMRLC 173
KI ++ A K +AT+KE+ G +KE ++EK E R + + E+M
Sbjct: 837 KIKPLLKSAETEKEMATMKEEFGRIKE--------------TLEKSEARRKELEEKMVSL 882
Query: 174 LAVKDYIRTQIISKKINTKFFQE------ENTEKLKLKYYNLMIQLDQHEGSYLSICKHY 227
L K+ ++ Q+ +++ N +E +N +L+ K + +L+ E +
Sbjct: 883 LQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKK 942
Query: 228 RAIYDTPCIQAESEKWQQALKSVVLYVILAPFDNEQSDLVHRISG-DKKLEEIPKYKDLL 286
R + D C + + + L + +N+ +L ++G D+ + ++ K K L
Sbjct: 943 RKLED-ECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKAL 1001
Query: 287 KLFTTMELMRWSTLVEDYGMELRKG--SLESPATDVFGSTEEGEKRWKDLK--NRVVEHN 342
+ + + + ED L K LE D+ GS E+ +K DL+ R +E +
Sbjct: 1002 Q-EAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGD 1060
Query: 343 IRI 345
+++
Sbjct: 1061 LKL 1063
>gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapiens]
Length = 1478
Score = 34.7 bits (78), Expect = 0.17
Identities = 45/233 (19%), Positives = 99/233 (42%), Gaps = 19/233 (8%)
Query: 4 GGSERADGRIVKMEVDYSATVDQRLPECAKLAKASDMVSTSRILVAVVKMCYEA------ 57
G +R ++V ++ A +D + ++L+ A ++ + LV +K EA
Sbjct: 783 GEVQRLQAQVVDLQAKMRAALDDQDKVQSQLSMAEAVLREHKTLVQQLKEQNEALNRAHV 842
Query: 58 --------KEWDLLNENIMLLSKRRSQLKQAVAKMVQQCCTYVE---EITDLPIKLRLID 106
+E L E +R +L+ ++ Q C+ E E +L +L +
Sbjct: 843 QELLQCSEREGALQEERADEAQQREEELRALQEELSQAKCSSEEAQLEHAELQEQLHRAN 902
Query: 107 TLRMVTEGKIY-VEIERARLTKTLATIKEQNGDVKEAASILQE-LQVETYGSMEKKERVE 164
T ++ + +E+ R+ + LA ++ D KEAAS +E L+ + G ++KE ++
Sbjct: 903 TDTAELGIQVCALTVEKERVEEALACAVQELQDAKEAASREREGLERQVAGLQQEKESLQ 962
Query: 165 FILEQMRLCLAVKDYIRTQIISKKINTKFFQEENTEKLKLKYYNLMIQLDQHE 217
L+ + ++ Q+ + + QE ++L + L ++ ++
Sbjct: 963 EKLKAAKAAAGSLPGLQAQLAQAEQRAQSLQEAAHQELNTLKFQLSAEIMDYQ 1015
>gi|115511012 coiled-coil domain containing 136 [Homo sapiens]
Length = 1154
Score = 34.7 bits (78), Expect = 0.17
Identities = 42/211 (19%), Positives = 85/211 (40%), Gaps = 22/211 (10%)
Query: 52 KMCYEAKEWDLLNENIMLLSKRRSQLKQAVAKMVQQCCTYVEEITDLPI----------- 100
++C K++D + L K + QL+ + ++ T VE ++ +
Sbjct: 370 RLCTLQKKYDTSQDEQNELLKMQLQLQTELRQLKVMKSTLVENQSEKELLCRLQKLHLQH 429
Query: 101 ------KLRLIDTLRMVTEGKIYVEIERARLTKTLATIKEQNGDVKEAASILQELQVETY 154
K +L++ + + E E E L T+A+ KE N E + LQE++
Sbjct: 430 QNVTCEKEKLLERQQQLQEELQCHEAELQHLRDTVASFKESNEKDTETHAQLQEMKQLYQ 489
Query: 155 GSMEKKERVEFILEQMRLCLAVKDYIRTQIISKKINTKFFQEENTEKLKLKYYNLMIQLD 214
S ++ ER + + +Q+ +D + Q+ K++ E+ K K L+ +L
Sbjct: 490 ASKDELERQKHMYDQLE-----QDLLLCQLELKELKASHPIPEDKGKCANKCDTLLSRLT 544
Query: 215 QHEGSYLSICKHYRAIYDTPCIQAESEKWQQ 245
+ + Y + K + C E ++ Q
Sbjct: 545 ELQEKYKASQKEMGQLQMEQCELLEDQRRMQ 575
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 34.7 bits (78), Expect = 0.17
Identities = 82/455 (18%), Positives = 173/455 (38%), Gaps = 50/455 (10%)
Query: 7 ERADGRIVKMEVD-------YSATVDQRLPECAKLAKASDMVSTSRILVAVVKMCYEAKE 59
ER +I+++E++ Y +D++ E + L + + + + +
Sbjct: 687 ERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEER 746
Query: 60 WDLLNE--NIMLLSKRRSQLKQAVAKMV----QQCCTYVEEITDLPIKLRLIDTLRMVTE 113
LL++ + ++++ R+Q+KQ + Q+ Y + + I +L + +
Sbjct: 747 DQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSLSIEAK 806
Query: 114 GK-IYVEIERARLTKTLATIKEQNGDVKEAASILQELQVETYGSMEKKERVEFILEQMRL 172
K + +E+ + L EQ+ ++ S LQ + E E+ + +E++
Sbjct: 807 SKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQ 866
Query: 173 CLAVKDYIRTQ----IISKKINTKFFQEENTEK------LKLKYYNLMIQLDQHEGSYLS 222
L+ K+ T+ ++ KK + + Q+ EK + M+QL++ + S
Sbjct: 867 ALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGV 926
Query: 223 ICKHYRAIYDTPCIQAESEKWQQALKSVVLYVILAPFDN-------EQSDLVHRISGDKK 275
K + + E++K Q + V + +D + +L H KK
Sbjct: 927 EIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKK 986
Query: 276 LEEIPKYKDLLKLFTTMELM-RWSTLVEDYGMELRKGSLESPATDVFGSTEEGEKRWKDL 334
E K K L EL+ R S L E+ + E P ++ E +K K+
Sbjct: 987 ENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEY 1046
Query: 335 KNRVVEHNIRIMAKYYTRITMKRMAQLLDLSVDESEAFLSNLVVNKTIFAKVDRLAGIIN 394
+ V + + Y + ++ +L + D E +LA
Sbjct: 1047 SEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEE-----------------KLAAEEQ 1089
Query: 395 FQR-PKDPNNLLNDWSQKLNSLMSLVNKTTHLIAK 428
FQ K N L D + +++ L + +++ +I K
Sbjct: 1090 FQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQK 1124
Score = 30.4 bits (67), Expect = 3.3
Identities = 37/155 (23%), Positives = 75/155 (48%), Gaps = 27/155 (17%)
Query: 138 DVKEAASILQELQV--------ETYGSMEKKERVEFILEQMRLCL--AVKDYIRTQIISK 187
+++ ++S Q L+V ET S + + + + E +R L ++K+ + ++ +
Sbjct: 2990 ELRSSSSQTQPLKVQYQRQASPETSASPDGSQNLVYETELLRTQLNDSLKEIHQKELRIQ 3049
Query: 188 KINTKFFQ---EENTEKLKLKYYNLMIQLDQ-HEGSYLSICKHYRAIYDTPCIQAESEKW 243
++N+ F Q E+NT ++L + ++ +Q H G L+ C A EK
Sbjct: 3050 QLNSNFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHC-------------AVLEKQ 3096
Query: 244 QQALKSVVLYVILAPFDNEQSDLVHRISGDKKLEE 278
Q L++ L + +AP ++ + VHR S ++L E
Sbjct: 3097 VQELQAGPLNIDVAPGAPQEKNGVHRKSDPEELRE 3131
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 34.3 bits (77), Expect = 0.23
Identities = 45/194 (23%), Positives = 83/194 (42%), Gaps = 25/194 (12%)
Query: 52 KMCYEAKEWDLLNENIMLLSKRRSQLKQAVAKMVQQCCTYVEEITDLPIKLRLIDTLRMV 111
K+ EAK ++ NE + + ++L K+ +C +I DL + L ++ +
Sbjct: 912 KIQLEAKVKEM-NERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHA 970
Query: 112 TEGKI-YVEIERARLTKTLATIKEQNGDVKEA-ASILQELQVE----------------- 152
TE K+ + E A L + +A + ++ ++EA L +LQ E
Sbjct: 971 TENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQ 1030
Query: 153 ---TYGSMEKKERVEFILEQMRLCLAVKDYIRTQIISKKINTKFFQEENTEK--LKLKYY 207
GS+E++++V LE+ + L + + I N K +E +K +L
Sbjct: 1031 VDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNAL 1090
Query: 208 NLMIQLDQHEGSYL 221
N I+ +Q GS L
Sbjct: 1091 NARIEDEQALGSQL 1104
>gi|187761324 shootin1 isoform a [Homo sapiens]
Length = 631
Score = 34.3 bits (77), Expect = 0.23
Identities = 56/242 (23%), Positives = 98/242 (40%), Gaps = 43/242 (17%)
Query: 104 LIDTLRMVTEGKIYVEIERARLTKTLATIKEQNGDVKEAASILQELQVETYGSMEKKERV 163
L D + V E K + IE L L + E+ VK+ ++L +E +EK RV
Sbjct: 147 LRDQIVSVQEEKKILAIELENLKSKLVEVIEEVNKVKQEKTVLNSEVLEQRKVLEKCNRV 206
Query: 164 EFILEQMRLCLAVKDYIRTQI---ISKKINTK---FFQEENTEKLKLK-YYNLMIQLDQH 216
LAV++Y Q+ + K + K F QE E+ KLK +L++Q
Sbjct: 207 SM--------LAVEEYEEMQVNLELEKDLRKKAESFAQEMFIEQNKLKRQSHLLLQSSIP 258
Query: 217 EGSYLSICKHYRAIYDTPCIQAESEKWQQALKSVVLYVILAPFDNEQSDLVHRISGDKKL 276
+ L + T ++ E + QQ +K + +++L
Sbjct: 259 DQQLLKALDENAKL--TQQLEEERIQHQQKVKEL----------------------EEQL 294
Query: 277 EEIPKYKDLLKLFTTMELMRWSTLVEDYGMELRKGSLESPATDVFGSTEEGEKRWKDLKN 336
E +K++ L +EL+ + +EL+ + E A ++ S +E +KR +N
Sbjct: 295 ENETLHKEIHNLKQQLELLE----EDKKELELKYQNSEEKARNLKHSVDELQKRVNQSEN 350
Query: 337 RV 338
V
Sbjct: 351 SV 352
>gi|50511340 shootin1 isoform b [Homo sapiens]
Length = 456
Score = 34.3 bits (77), Expect = 0.23
Identities = 56/242 (23%), Positives = 98/242 (40%), Gaps = 43/242 (17%)
Query: 104 LIDTLRMVTEGKIYVEIERARLTKTLATIKEQNGDVKEAASILQELQVETYGSMEKKERV 163
L D + V E K + IE L L + E+ VK+ ++L +E +EK RV
Sbjct: 147 LRDQIVSVQEEKKILAIELENLKSKLVEVIEEVNKVKQEKTVLNSEVLEQRKVLEKCNRV 206
Query: 164 EFILEQMRLCLAVKDYIRTQI---ISKKINTK---FFQEENTEKLKLK-YYNLMIQLDQH 216
LAV++Y Q+ + K + K F QE E+ KLK +L++Q
Sbjct: 207 SM--------LAVEEYEEMQVNLELEKDLRKKAESFAQEMFIEQNKLKRQSHLLLQSSIP 258
Query: 217 EGSYLSICKHYRAIYDTPCIQAESEKWQQALKSVVLYVILAPFDNEQSDLVHRISGDKKL 276
+ L + T ++ E + QQ +K + +++L
Sbjct: 259 DQQLLKALDENAKL--TQQLEEERIQHQQKVKEL----------------------EEQL 294
Query: 277 EEIPKYKDLLKLFTTMELMRWSTLVEDYGMELRKGSLESPATDVFGSTEEGEKRWKDLKN 336
E +K++ L +EL+ + +EL+ + E A ++ S +E +KR +N
Sbjct: 295 ENETLHKEIHNLKQQLELLE----EDKKELELKYQNSEEKARNLKHSVDELQKRVNQSEN 350
Query: 337 RV 338
V
Sbjct: 351 SV 352
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 33.5 bits (75), Expect = 0.39
Identities = 37/157 (23%), Positives = 68/157 (43%), Gaps = 11/157 (7%)
Query: 70 LSKRRSQLKQAVAKMVQQCCTYVEEITDLPIKLRLIDTLRMVTEGKIYVEIER-----AR 124
L + QL++ + + C E L K + ++ + E ++ E ER A
Sbjct: 878 LMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAE 937
Query: 125 LTKTLATIKEQNGDVKEAASILQELQVE---TYGSMEKKERVEFILEQMRLCLAVKDYIR 181
K I+E ++E S Q+LQ+E T ++K E + ILE LA + +
Sbjct: 938 KKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLL 997
Query: 182 TQIISKKINTKFFQEENTE---KLKLKYYNLMIQLDQ 215
I++ +EE ++ KLK K+ ++ L++
Sbjct: 998 EDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEE 1034
>gi|64085252 hypothetical protein LOC145508 [Homo sapiens]
Length = 1094
Score = 33.1 bits (74), Expect = 0.51
Identities = 40/172 (23%), Positives = 79/172 (45%), Gaps = 28/172 (16%)
Query: 63 LNENIMLLSKRRSQLKQAVAKMVQQCCTYVEEITDLPIKLRLID--TLRMVTEGKIYVEI 120
+ E+I LS R+ L +A+ + +++++DL + + D T ++T+ K+ ++
Sbjct: 633 MQESIKDLSAIRADLANKLAEEERAKKAVLKDLSDLTAQAKSRDEETATIITQLKLERDV 692
Query: 121 ERARL---TKTLATIK---EQN---------GDVKEAASILQELQVETYGSMEKKERVEF 165
+ L T +L ++K EQN + EA + ++ L+ E S+E+K +
Sbjct: 693 HQRELKDLTSSLQSVKTKHEQNIQELMKHFKKEKSEAENHIRTLKAE---SLEEKNMAKI 749
Query: 166 ILEQMRLCLAVKDYIRTQIISKKINTKFFQEENTEKLKLKYYNLMIQLDQHE 217
Q+ + D + ++ E +KLKLKY L QL++ E
Sbjct: 750 HRGQLEKLKSQCDRLTEELTQN--------ENENKKLKLKYQCLKDQLEERE 793
>gi|154426264 ubiquitin protein ligase E3 component n-recognin 7
(putative) isoform 3 [Homo sapiens]
Length = 349
Score = 32.7 bits (73), Expect = 0.66
Identities = 26/104 (25%), Positives = 52/104 (50%), Gaps = 12/104 (11%)
Query: 115 KIYVEIERARLTKTLATIK--EQNGDVKEAASILQELQVETYGSMEKKERVEFILEQMRL 172
K+Y +++ LT T+ E G + +A L ++T SM + ++VE I E L
Sbjct: 245 KMYGDLDVLFLTDEYDTVLAYENKGKIAQATDRSDPL-MDTLSSMNRVQQVELICEYNDL 303
Query: 173 CLAVKDYIRT-----QIISKKINTKFFQEENTEKLK----LKYY 207
+KDY++ ++ ++ +FF+E ++K + ++YY
Sbjct: 304 KTELKDYLKRFADEGTVVKREDIQQFFEEFQSKKRRRVDGMQYY 347
>gi|154426322 ubiquitin protein ligase E3 component n-recognin 7
(putative) isoform 2 [Homo sapiens]
Length = 425
Score = 32.7 bits (73), Expect = 0.66
Identities = 26/104 (25%), Positives = 52/104 (50%), Gaps = 12/104 (11%)
Query: 115 KIYVEIERARLTKTLATIK--EQNGDVKEAASILQELQVETYGSMEKKERVEFILEQMRL 172
K+Y +++ LT T+ E G + +A L ++T SM + ++VE I E L
Sbjct: 321 KMYGDLDVLFLTDEYDTVLAYENKGKIAQATDRSDPL-MDTLSSMNRVQQVELICEYNDL 379
Query: 173 CLAVKDYIRT-----QIISKKINTKFFQEENTEKLK----LKYY 207
+KDY++ ++ ++ +FF+E ++K + ++YY
Sbjct: 380 KTELKDYLKRFADEGTVVKREDIQQFFEEFQSKKRRRVDGMQYY 423
>gi|23238222 COP9 constitutive photomorphogenic homolog subunit 3
[Homo sapiens]
Length = 423
Score = 32.7 bits (73), Expect = 0.66
Identities = 21/91 (23%), Positives = 52/91 (57%), Gaps = 4/91 (4%)
Query: 332 KDLKNRVVEHNIRIMAKYYTRITMKRMAQLLDLS-VDESEAFLSNLVVNKTIFAKVDRLA 390
K + + + NI+ + K + ++++ MA + LS E+E ++ +++ + IFA +++
Sbjct: 296 KQCLSSLYKKNIQRLTKTFLTLSLQDMASRVQLSGPQEAEKYVLHMIEDGEIFASINQKD 355
Query: 391 GIINF-QRPKDPNN--LLNDWSQKLNSLMSL 418
G+++F P+ NN +L++ Q++ + L
Sbjct: 356 GMVSFHDNPEKYNNPAMLHNIDQEMLKCIEL 386
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 32.7 bits (73), Expect = 0.66
Identities = 55/241 (22%), Positives = 95/241 (39%), Gaps = 35/241 (14%)
Query: 132 IKEQNGDVKEAASILQELQVETYGSMEKKERVEFILEQMRLCLAVKDYIRTQIISKKINT 191
+KEQ V+ A++LQ E + ++E+ ER I EQ L + + + + INT
Sbjct: 1670 LKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINT 1729
Query: 192 KFFQEENTEKLKLKYYNLMIQLDQHEGSYLSICKHYRAIYDTPCIQAESEKWQQALKSVV 251
K E + +L+ + ++ + E K +AI D + E +K Q S
Sbjct: 1730 KKKLENDVSQLQSEVEEVIQESRNAEE------KAKKAITDAAMMAEELKKEQDT--SAH 1781
Query: 252 LYVILAPFDNEQSDLVHRISGDKKLEEIPKYKDLLKLFTTMELMRWSTLVEDYGMELRKG 311
L + + DL HR+ ++L K + K
Sbjct: 1782 LERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQK------------------------ 1817
Query: 312 SLESPATDVFGSTEEGEKRWKDLKNRVVEHNIRIM-AKYYTRITMKRMAQLLDLSVDESE 370
LE+ ++ G E +KR + + +H R+ Y T K + +L DL VD+ +
Sbjct: 1818 -LEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDL-VDKLQ 1875
Query: 371 A 371
A
Sbjct: 1876 A 1876
>gi|7661914 proteasome (prosome, macropain) 26S subunit, non-ATPase,
6 [Homo sapiens]
Length = 389
Score = 32.3 bits (72), Expect = 0.87
Identities = 19/86 (22%), Positives = 40/86 (46%)
Query: 341 HNIRIMAKYYTRITMKRMAQLLDLSVDESEAFLSNLVVNKTIFAKVDRLAGIINFQRPKD 400
H + + Y +T+ MA+ + V+ + LS + + K+D++ I+ RP
Sbjct: 302 HAYSQLLESYRSLTLGYMAEAFGVGVEFIDQELSRFIAAGRLHCKIDKVNEIVETNRPDS 361
Query: 401 PNNLLNDWSQKLNSLMSLVNKTTHLI 426
N + +K + L++ V K + +I
Sbjct: 362 KNWQYQETIKKGDLLLNRVQKLSRVI 387
>gi|219689136 coiled-coil domain containing 68 [Homo sapiens]
Length = 335
Score = 31.6 bits (70), Expect = 1.5
Identities = 37/165 (22%), Positives = 81/165 (49%), Gaps = 19/165 (11%)
Query: 63 LNENIMLLSKRRSQ---LKQAVAKMVQQCCTYVEEITDLPIKLRLIDTLRMVTEGKIYVE 119
LN+ L ++ SQ L+ V +M ++ T +E L ++ +L+ T GK +
Sbjct: 174 LNQVAEKLEEKHSQITELENLVQRMEKEKRTLLER--KLSLENKLLQLKSSATYGKSCQD 231
Query: 120 IERA------RLTKTLATIKEQNGDVKEAASILQELQVETYGSMEKKERVEFILEQMRLC 173
++R +++ I Q+ +++ S++QE++ E+ +R+E + E++ +
Sbjct: 232 LQREISILQEQISHLQFVIHSQHQNLR---SVIQEMEGLKNNLKEQDKRIENLREKVNIL 288
Query: 174 LAVKDYIRTQII--SKKINTKFFQEENTEKLK---LKYYNLMIQL 213
A ++TQ+ S+ TK + +T +LK + Y ++I+L
Sbjct: 289 EAQNKELKTQVALSSETPRTKVSKAVSTSELKTEGVSPYLMLIRL 333
>gi|13376818 coiled-coil domain containing 68 [Homo sapiens]
Length = 335
Score = 31.6 bits (70), Expect = 1.5
Identities = 37/165 (22%), Positives = 81/165 (49%), Gaps = 19/165 (11%)
Query: 63 LNENIMLLSKRRSQ---LKQAVAKMVQQCCTYVEEITDLPIKLRLIDTLRMVTEGKIYVE 119
LN+ L ++ SQ L+ V +M ++ T +E L ++ +L+ T GK +
Sbjct: 174 LNQVAEKLEEKHSQITELENLVQRMEKEKRTLLER--KLSLENKLLQLKSSATYGKSCQD 231
Query: 120 IERA------RLTKTLATIKEQNGDVKEAASILQELQVETYGSMEKKERVEFILEQMRLC 173
++R +++ I Q+ +++ S++QE++ E+ +R+E + E++ +
Sbjct: 232 LQREISILQEQISHLQFVIHSQHQNLR---SVIQEMEGLKNNLKEQDKRIENLREKVNIL 288
Query: 174 LAVKDYIRTQII--SKKINTKFFQEENTEKLK---LKYYNLMIQL 213
A ++TQ+ S+ TK + +T +LK + Y ++I+L
Sbjct: 289 EAQNKELKTQVALSSETPRTKVSKAVSTSELKTEGVSPYLMLIRL 333
>gi|118498362 kinectin 1 isoform b [Homo sapiens]
Length = 1306
Score = 31.6 bits (70), Expect = 1.5
Identities = 25/93 (26%), Positives = 45/93 (48%), Gaps = 4/93 (4%)
Query: 118 VEIERARLTKTLATIKEQNGDVKEAASILQELQVETYGSMEKKERVEFILEQMRLCLAVK 177
+ E + LTK + +K + D AS+++EL+ + K + VE +LE L +A K
Sbjct: 768 IRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANK 827
Query: 178 DYIRTQIISKKINTKFFQEENTEKLKLKYYNLM 210
+ + + I +K + +N K K + N M
Sbjct: 828 E----KTVQLSITSKVQELQNLLKGKEEQMNTM 856
>gi|23397429 eukaryotic translation initiation factor 3, subunit M
[Homo sapiens]
Length = 374
Score = 31.6 bits (70), Expect = 1.5
Identities = 25/87 (28%), Positives = 39/87 (44%), Gaps = 14/87 (16%)
Query: 346 MAKYYTRITMKRMAQLLDLSVDESEAFLSNLVVNKTIFAKVDRLAGII----------NF 395
MA I+ M Q L + D+ EAF+ + V K ++ K+D+ +
Sbjct: 285 MAVENKEISFDTMQQELQIGADDVEAFVIDAVRTKMVYCKIDQTQRKVVVSHSTHRTFGK 344
Query: 396 QRPKDPNNLLNDWSQKL----NSLMSL 418
Q+ + + LN W Q L NSL+SL
Sbjct: 345 QQWQQLYDTLNAWKQNLNKVKNSLLSL 371
>gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1
[Homo sapiens]
Length = 1288
Score = 31.6 bits (70), Expect = 1.5
Identities = 32/134 (23%), Positives = 52/134 (38%), Gaps = 19/134 (14%)
Query: 35 AKASDMVSTSRILVAVVKMCYEAKE----WDLLNENIMLLSKRRSQLKQAVAKMVQQCCT 90
AK D+ T + L + K E KE DL + + K + + + K +Q+
Sbjct: 364 AKNKDVKDTEKKLNKITKFIEENKEKFTQLDLEDVQVREKLKHATSKAKKLEKQLQKDKE 423
Query: 91 YVEEITDLPIKLRLIDTLRMVTEGKIYVEIERARLTKTLATIKEQNGDVKEAASILQELQ 150
VEE +P K I T+ A KE+ + K+ ++ L+
Sbjct: 424 KVEEFKSIPAKSN---------------NIINETTTRNNALEKEKEKEEKKLKEVMDSLK 468
Query: 151 VETYGSMEKKERVE 164
ET G ++KE E
Sbjct: 469 QETQGLQKEKESRE 482
>gi|63999048 syntaxin binding protein 4 [Homo sapiens]
Length = 553
Score = 31.6 bits (70), Expect = 1.5
Identities = 24/96 (25%), Positives = 46/96 (47%), Gaps = 5/96 (5%)
Query: 58 KEWDLLNENIMLLSKRRSQLKQAVAKMVQQCCTYVEEITDLPIKLRLIDTLRMVTEG--K 115
KE + L E ++ K+R QL + + + Q+ VEE L ++ L + + G
Sbjct: 309 KEVNTLKEKLLESDKQRKQLTEELQNVKQEAKAVVEETRALRSRIHLAEAAQRQAHGMEM 368
Query: 116 IYVEIER---ARLTKTLATIKEQNGDVKEAASILQE 148
Y E+ R A++T+ A + + + KE+ L++
Sbjct: 369 DYEEVIRLLEAKITELKAQLADYSDQNKESVQDLKK 404
>gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1
[Homo sapiens]
Length = 1288
Score = 31.6 bits (70), Expect = 1.5
Identities = 32/134 (23%), Positives = 52/134 (38%), Gaps = 19/134 (14%)
Query: 35 AKASDMVSTSRILVAVVKMCYEAKE----WDLLNENIMLLSKRRSQLKQAVAKMVQQCCT 90
AK D+ T + L + K E KE DL + + K + + + K +Q+
Sbjct: 364 AKNKDVKDTEKKLNKITKFIEENKEKFTQLDLEDVQVREKLKHATSKAKKLEKQLQKDKE 423
Query: 91 YVEEITDLPIKLRLIDTLRMVTEGKIYVEIERARLTKTLATIKEQNGDVKEAASILQELQ 150
VEE +P K I T+ A KE+ + K+ ++ L+
Sbjct: 424 KVEEFKSIPAKSN---------------NIINETTTRNNALEKEKEKEEKKLKEVMDSLK 468
Query: 151 VETYGSMEKKERVE 164
ET G ++KE E
Sbjct: 469 QETQGLQKEKESRE 482
>gi|28269672 serologically defined colon cancer antigen 8 [Homo
sapiens]
Length = 713
Score = 31.2 bits (69), Expect = 1.9
Identities = 33/141 (23%), Positives = 69/141 (48%), Gaps = 18/141 (12%)
Query: 56 EAKEWDLLNENIMLLSKRRSQLKQAVAKMVQQCCTYVEEITDLPIKLRLIDTLRMVTEGK 115
EA+ NE +LL+ + + L K+ ++CCT +++ + K R + +++ K
Sbjct: 575 EAQHDKTENEQYLLLTSQNTFL----TKLKEECCTLAKKLEQISQKTR--SEIAQLSQEK 628
Query: 116 IYVEIERARLTKTLATIKE---QNGDVKEAASILQEL-QVETYGSMEKKERVEFILEQMR 171
Y + +L + ++E Q+G V E ++ Q L Q++ + ++ V+ + +Q +
Sbjct: 629 RYTYDKLGKLQRRNEELEEQCVQHGRVHE--TMKQRLRQLDKHSQATAQQLVQLLSKQNQ 686
Query: 172 LCLAVK------DYIRTQIIS 186
L L + D +RTQ+ S
Sbjct: 687 LLLERQSLSEEVDRLRTQLPS 707
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.132 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,964,933
Number of Sequences: 37866
Number of extensions: 546004
Number of successful extensions: 1890
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 51
Number of HSP's that attempted gapping in prelim test: 1830
Number of HSP's gapped (non-prelim): 107
length of query: 436
length of database: 18,247,518
effective HSP length: 105
effective length of query: 331
effective length of database: 14,271,588
effective search space: 4723895628
effective search space used: 4723895628
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.