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Search of human proteins with 28872761
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|28872761 myotubularin-related protein 1 [Homo sapiens]
(665 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|28872761 myotubularin-related protein 1 [Homo sapiens] 1355 0.0
gi|44680154 myotubularin-related protein 2 isoform 1 [Homo sapiens] 925 0.0
gi|41350318 myotubularin-related protein 2 isoform 2 [Homo sapiens] 885 0.0
gi|41350316 myotubularin-related protein 2 isoform 2 [Homo sapiens] 885 0.0
gi|4557896 myotubularin [Homo sapiens] 728 0.0
gi|21361759 myotubularin related protein 8 [Homo sapiens] 358 1e-98
gi|134142348 myotubularin related protein 6 [Homo sapiens] 347 2e-95
gi|225543474 myotubularin related protein 7 [Homo sapiens] 329 4e-90
gi|19923424 myotubularin related protein 9 [Homo sapiens] 324 1e-88
gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens] 317 3e-86
gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens] 317 3e-86
gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens] 317 3e-86
gi|217272865 myotubularin related protein 4 [Homo sapiens] 303 3e-82
gi|124028527 myotubularin related protein 10 [Homo sapiens] 159 8e-39
gi|29788755 SET binding factor 2 [Homo sapiens] 143 6e-34
gi|239735519 SET binding factor 1 [Homo sapiens] 139 6e-33
gi|224994251 myotubularin related protein 11 isoform a [Homo sap... 137 3e-32
gi|89111941 myotubularin related protein 11 isoform b [Homo sapi... 137 3e-32
gi|94721263 myotubularin related protein 12 [Homo sapiens] 135 2e-31
gi|153792780 additional sex combs like 2 [Homo sapiens] 38 0.026
gi|117938274 jumpy isoform 3 [Homo sapiens] 37 0.045
gi|117938272 jumpy isoform 1 [Homo sapiens] 37 0.045
gi|117938270 jumpy isoform 2 [Homo sapiens] 37 0.045
gi|191250771 spire homolog 1 isoform b [Homo sapiens] 35 0.17
gi|191250773 spire homolog 1 isoform a [Homo sapiens] 35 0.17
gi|194294548 hsp70-interacting protein [Homo sapiens] 35 0.22
gi|112363070 hsp70-interacting protein [Homo sapiens] 35 0.22
gi|223633890 hypothetical protein LOC729956 [Homo sapiens] 35 0.29
gi|169790811 SHC (Src homology 2 domain containing) transforming... 35 0.29
gi|47578107 delangin isoform B [Homo sapiens] 35 0.29
>gi|28872761 myotubularin-related protein 1 [Homo sapiens]
Length = 665
Score = 1355 bits (3506), Expect = 0.0
Identities = 665/665 (100%), Positives = 665/665 (100%)
Query: 1 MDRPAAAAAAGCEGGGGPNPGPAGGRRPPRAAGGATAGSRQPSVETLDSPTGSHVEWCKQ 60
MDRPAAAAAAGCEGGGGPNPGPAGGRRPPRAAGGATAGSRQPSVETLDSPTGSHVEWCKQ
Sbjct: 1 MDRPAAAAAAGCEGGGGPNPGPAGGRRPPRAAGGATAGSRQPSVETLDSPTGSHVEWCKQ 60
Query: 61 LIAATISSQISGSVTSENVSRDYKALRDGNKLAQMEEAPLFPGESIKAIVKDVMYICPFM 120
LIAATISSQISGSVTSENVSRDYKALRDGNKLAQMEEAPLFPGESIKAIVKDVMYICPFM
Sbjct: 61 LIAATISSQISGSVTSENVSRDYKALRDGNKLAQMEEAPLFPGESIKAIVKDVMYICPFM 120
Query: 121 GAVSGTLTVTDFKLYFKNVERDPHFILDVPLGVISRVEKIGAQSHGDNSCGIEIVCKDMR 180
GAVSGTLTVTDFKLYFKNVERDPHFILDVPLGVISRVEKIGAQSHGDNSCGIEIVCKDMR
Sbjct: 121 GAVSGTLTVTDFKLYFKNVERDPHFILDVPLGVISRVEKIGAQSHGDNSCGIEIVCKDMR 180
Query: 181 NLRLAYKQEEQSKLGIFENLNKHAFPLSNGQALFAFSYKEKFPINGWKVYDPVSEYKRQG 240
NLRLAYKQEEQSKLGIFENLNKHAFPLSNGQALFAFSYKEKFPINGWKVYDPVSEYKRQG
Sbjct: 181 NLRLAYKQEEQSKLGIFENLNKHAFPLSNGQALFAFSYKEKFPINGWKVYDPVSEYKRQG 240
Query: 241 LPNESWKISKINSNYEFCDTYPAIIVVPTSVKDDDLSKVAAFRAKGRVPVLSWIHPESQA 300
LPNESWKISKINSNYEFCDTYPAIIVVPTSVKDDDLSKVAAFRAKGRVPVLSWIHPESQA
Sbjct: 241 LPNESWKISKINSNYEFCDTYPAIIVVPTSVKDDDLSKVAAFRAKGRVPVLSWIHPESQA 300
Query: 301 TITRCSQPLVGPNDKRCKEDEKYLQTIMDANAQSHKLIIFDARQNSVADTNKTKGGGYES 360
TITRCSQPLVGPNDKRCKEDEKYLQTIMDANAQSHKLIIFDARQNSVADTNKTKGGGYES
Sbjct: 301 TITRCSQPLVGPNDKRCKEDEKYLQTIMDANAQSHKLIIFDARQNSVADTNKTKGGGYES 360
Query: 361 ESAYPNAELVFLEIHNIHVMRESLRKLKEIVYPSIDEARWLSNVDGTHWLEYIRMLLAGA 420
ESAYPNAELVFLEIHNIHVMRESLRKLKEIVYPSIDEARWLSNVDGTHWLEYIRMLLAGA
Sbjct: 361 ESAYPNAELVFLEIHNIHVMRESLRKLKEIVYPSIDEARWLSNVDGTHWLEYIRMLLAGA 420
Query: 421 VRIADKIESGKTSVVVHCSDGWDRTAQLTSLAMLMLDSYYRTIKGFETLVEKEWISFGHR 480
VRIADKIESGKTSVVVHCSDGWDRTAQLTSLAMLMLDSYYRTIKGFETLVEKEWISFGHR
Sbjct: 421 VRIADKIESGKTSVVVHCSDGWDRTAQLTSLAMLMLDSYYRTIKGFETLVEKEWISFGHR 480
Query: 481 FALRVGHGNDNHADADRSPIFLQFVDCVWQMTRQFPSAFEFNELFLITILDHLYSCLFGT 540
FALRVGHGNDNHADADRSPIFLQFVDCVWQMTRQFPSAFEFNELFLITILDHLYSCLFGT
Sbjct: 481 FALRVGHGNDNHADADRSPIFLQFVDCVWQMTRQFPSAFEFNELFLITILDHLYSCLFGT 540
Query: 541 FLCNCEQQRFKEDVYTKTISLWSYINSQLDEFSNPFFVNYENHVLYPVASLSHLELWVNY 600
FLCNCEQQRFKEDVYTKTISLWSYINSQLDEFSNPFFVNYENHVLYPVASLSHLELWVNY
Sbjct: 541 FLCNCEQQRFKEDVYTKTISLWSYINSQLDEFSNPFFVNYENHVLYPVASLSHLELWVNY 600
Query: 601 YVRWNPRMRPQMPIHQNLKELLAVRAELQKRVEGLQREVATRAVSSSSERGSSPSHSATS 660
YVRWNPRMRPQMPIHQNLKELLAVRAELQKRVEGLQREVATRAVSSSSERGSSPSHSATS
Sbjct: 601 YVRWNPRMRPQMPIHQNLKELLAVRAELQKRVEGLQREVATRAVSSSSERGSSPSHSATS 660
Query: 661 VHTSV 665
VHTSV
Sbjct: 661 VHTSV 665
>gi|44680154 myotubularin-related protein 2 isoform 1 [Homo sapiens]
Length = 643
Score = 925 bits (2391), Expect = 0.0
Identities = 442/634 (69%), Positives = 530/634 (83%), Gaps = 2/634 (0%)
Query: 33 GGATAGSRQPSVETLDSPTGSHVEWCKQLIAATISSQISGSVTSENVSRDYKALRDGNKL 92
G A +R PSV++L S + SH E +A++ S S S +++N S D + LR+ NKL
Sbjct: 11 GSQPAAARPPSVDSLSSASTSHSENSVHTKSASVVSSDSISTSADNFSPDLRVLRESNKL 70
Query: 93 AQMEEAPLFPGESIKAIVKDVMYICPFMGAVSGTLTVTDFKLYFKNVERDPHFILDVPLG 152
A+MEE PL PGE+IK + KDV YICPF GAV GTLTVT+++LYFK++ERDP F+LD LG
Sbjct: 71 AEMEEPPLLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFKSMERDPPFVLDASLG 130
Query: 153 VISRVEKIG-AQSHGDNSCGIEIVCKDMRNLRLAYKQEEQSKLGIFENLNKHAFPLSNGQ 211
VI+RVEKIG A S G+NS G+E VCKD+RNLR A+K E +++ IFENL K+AFP+SN
Sbjct: 131 VINRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNL 190
Query: 212 ALFAFSYKEKFPINGWKVYDPVSEYKRQGLPNESWKISKINSNYEFCDTYPAIIVVPTSV 271
LFAF YKE FP NGWK+YDP+ EY+RQG+PNESW+I+KIN YE CDTYPA++VVP ++
Sbjct: 191 PLFAFEYKEVFPENGWKLYDPLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANI 250
Query: 272 KDDDLSKVAAFRAKGRVPVLSWIHPESQATITRCSQPLVGPNDKRCKEDEKYLQTIMDAN 331
D++L +VA+FR++GR+PVLSWIHPESQATITRCSQP+VG + KR KEDEKYLQ IMD+N
Sbjct: 251 PDEELKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSN 310
Query: 332 AQSHKLIIFDARQNSVADTNKTKGGGYESESAYPNAELVFLEIHNIHVMRESLRKLKEIV 391
AQSHK+ IFDAR + A NK KGGGYESE AY NAELVFL+IHNIHVMRESLRKLKEIV
Sbjct: 311 AQSHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIV 370
Query: 392 YPSIDEARWLSNVDGTHWLEYIRMLLAGAVRIADKIESGKTSVVVHCSDGWDRTAQLTSL 451
YP+I+E WLSN++ THWLE+I+++LAGA+RIADK+ESGKTSVVVHCSDGWDRTAQLTSL
Sbjct: 371 YPNIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSL 430
Query: 452 AMLMLDSYYRTIKGFETLVEKEWISFGHRFALRVGHGNDNHADADRSPIFLQFVDCVWQM 511
AMLMLD YYRTI+GFE LVEKEW+SFGHRF LRVGHG+ NHADADRSP+FLQF+DCVWQM
Sbjct: 431 AMLMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQM 490
Query: 512 TRQFPSAFEFNELFLITILDHLYSCLFGTFLCNCEQQRFKEDVYTKTISLWSYINSQLDE 571
TRQFP+AFEFNE FLITILDHLYSCLFGTFLCN EQQR KE++ +T+SLWSYINSQL++
Sbjct: 491 TRQFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLED 550
Query: 572 FSNPFFVNYENHVLYPVASLSHLELWVNYYVRWNPRMRPQMPIHQNLKELLAVRAELQKR 631
F+NP + +Y NHVLYPVAS+ HLELWV YY+RWNPRM+PQ PIH KELLA RAELQK+
Sbjct: 551 FTNPLYGSYSNHVLYPVASMRHLELWVGYYIRWNPRMKPQEPIHNRYKELLAKRAELQKK 610
Query: 632 VEGLQREVATRAVSSSSERGSSPSHSATSVHTSV 665
VE LQRE++ R+ +SSSER SSP+ T V T V
Sbjct: 611 VEELQREISNRS-TSSSERASSPAQCVTPVQTVV 643
>gi|41350318 myotubularin-related protein 2 isoform 2 [Homo sapiens]
Length = 571
Score = 885 bits (2288), Expect = 0.0
Identities = 418/572 (73%), Positives = 493/572 (86%), Gaps = 2/572 (0%)
Query: 95 MEEAPLFPGESIKAIVKDVMYICPFMGAVSGTLTVTDFKLYFKNVERDPHFILDVPLGVI 154
MEE PL PGE+IK + KDV YICPF GAV GTLTVT+++LYFK++ERDP F+LD LGVI
Sbjct: 1 MEEPPLLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFKSMERDPPFVLDASLGVI 60
Query: 155 SRVEKIG-AQSHGDNSCGIEIVCKDMRNLRLAYKQEEQSKLGIFENLNKHAFPLSNGQAL 213
+RVEKIG A S G+NS G+E VCKD+RNLR A+K E +++ IFENL K+AFP+SN L
Sbjct: 61 NRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPL 120
Query: 214 FAFSYKEKFPINGWKVYDPVSEYKRQGLPNESWKISKINSNYEFCDTYPAIIVVPTSVKD 273
FAF YKE FP NGWK+YDP+ EY+RQG+PNESW+I+KIN YE CDTYPA++VVP ++ D
Sbjct: 121 FAFEYKEVFPENGWKLYDPLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPD 180
Query: 274 DDLSKVAAFRAKGRVPVLSWIHPESQATITRCSQPLVGPNDKRCKEDEKYLQTIMDANAQ 333
++L +VA+FR++GR+PVLSWIHPESQATITRCSQP+VG + KR KEDEKYLQ IMD+NAQ
Sbjct: 181 EELKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQ 240
Query: 334 SHKLIIFDARQNSVADTNKTKGGGYESESAYPNAELVFLEIHNIHVMRESLRKLKEIVYP 393
SHK+ IFDAR + A NK KGGGYESE AY NAELVFL+IHNIHVMRESLRKLKEIVYP
Sbjct: 241 SHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYP 300
Query: 394 SIDEARWLSNVDGTHWLEYIRMLLAGAVRIADKIESGKTSVVVHCSDGWDRTAQLTSLAM 453
+I+E WLSN++ THWLE+I+++LAGA+RIADK+ESGKTSVVVHCSDGWDRTAQLTSLAM
Sbjct: 301 NIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAM 360
Query: 454 LMLDSYYRTIKGFETLVEKEWISFGHRFALRVGHGNDNHADADRSPIFLQFVDCVWQMTR 513
LMLD YYRTI+GFE LVEKEW+SFGHRF LRVGHG+ NHADADRSP+FLQF+DCVWQMTR
Sbjct: 361 LMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTR 420
Query: 514 QFPSAFEFNELFLITILDHLYSCLFGTFLCNCEQQRFKEDVYTKTISLWSYINSQLDEFS 573
QFP+AFEFNE FLITILDHLYSCLFGTFLCN EQQR KE++ +T+SLWSYINSQL++F+
Sbjct: 421 QFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFT 480
Query: 574 NPFFVNYENHVLYPVASLSHLELWVNYYVRWNPRMRPQMPIHQNLKELLAVRAELQKRVE 633
NP + +Y NHVLYPVAS+ HLELWV YY+RWNPRM+PQ PIH KELLA RAELQK+VE
Sbjct: 481 NPLYGSYSNHVLYPVASMRHLELWVGYYIRWNPRMKPQEPIHNRYKELLAKRAELQKKVE 540
Query: 634 GLQREVATRAVSSSSERGSSPSHSATSVHTSV 665
LQRE++ R+ +SSSER SSP+ T V T V
Sbjct: 541 ELQREISNRS-TSSSERASSPAQCVTPVQTVV 571
>gi|41350316 myotubularin-related protein 2 isoform 2 [Homo sapiens]
Length = 571
Score = 885 bits (2288), Expect = 0.0
Identities = 418/572 (73%), Positives = 493/572 (86%), Gaps = 2/572 (0%)
Query: 95 MEEAPLFPGESIKAIVKDVMYICPFMGAVSGTLTVTDFKLYFKNVERDPHFILDVPLGVI 154
MEE PL PGE+IK + KDV YICPF GAV GTLTVT+++LYFK++ERDP F+LD LGVI
Sbjct: 1 MEEPPLLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFKSMERDPPFVLDASLGVI 60
Query: 155 SRVEKIG-AQSHGDNSCGIEIVCKDMRNLRLAYKQEEQSKLGIFENLNKHAFPLSNGQAL 213
+RVEKIG A S G+NS G+E VCKD+RNLR A+K E +++ IFENL K+AFP+SN L
Sbjct: 61 NRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPL 120
Query: 214 FAFSYKEKFPINGWKVYDPVSEYKRQGLPNESWKISKINSNYEFCDTYPAIIVVPTSVKD 273
FAF YKE FP NGWK+YDP+ EY+RQG+PNESW+I+KIN YE CDTYPA++VVP ++ D
Sbjct: 121 FAFEYKEVFPENGWKLYDPLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPD 180
Query: 274 DDLSKVAAFRAKGRVPVLSWIHPESQATITRCSQPLVGPNDKRCKEDEKYLQTIMDANAQ 333
++L +VA+FR++GR+PVLSWIHPESQATITRCSQP+VG + KR KEDEKYLQ IMD+NAQ
Sbjct: 181 EELKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQ 240
Query: 334 SHKLIIFDARQNSVADTNKTKGGGYESESAYPNAELVFLEIHNIHVMRESLRKLKEIVYP 393
SHK+ IFDAR + A NK KGGGYESE AY NAELVFL+IHNIHVMRESLRKLKEIVYP
Sbjct: 241 SHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYP 300
Query: 394 SIDEARWLSNVDGTHWLEYIRMLLAGAVRIADKIESGKTSVVVHCSDGWDRTAQLTSLAM 453
+I+E WLSN++ THWLE+I+++LAGA+RIADK+ESGKTSVVVHCSDGWDRTAQLTSLAM
Sbjct: 301 NIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAM 360
Query: 454 LMLDSYYRTIKGFETLVEKEWISFGHRFALRVGHGNDNHADADRSPIFLQFVDCVWQMTR 513
LMLD YYRTI+GFE LVEKEW+SFGHRF LRVGHG+ NHADADRSP+FLQF+DCVWQMTR
Sbjct: 361 LMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTR 420
Query: 514 QFPSAFEFNELFLITILDHLYSCLFGTFLCNCEQQRFKEDVYTKTISLWSYINSQLDEFS 573
QFP+AFEFNE FLITILDHLYSCLFGTFLCN EQQR KE++ +T+SLWSYINSQL++F+
Sbjct: 421 QFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFT 480
Query: 574 NPFFVNYENHVLYPVASLSHLELWVNYYVRWNPRMRPQMPIHQNLKELLAVRAELQKRVE 633
NP + +Y NHVLYPVAS+ HLELWV YY+RWNPRM+PQ PIH KELLA RAELQK+VE
Sbjct: 481 NPLYGSYSNHVLYPVASMRHLELWVGYYIRWNPRMKPQEPIHNRYKELLAKRAELQKKVE 540
Query: 634 GLQREVATRAVSSSSERGSSPSHSATSVHTSV 665
LQRE++ R+ +SSSER SSP+ T V T V
Sbjct: 541 ELQREISNRS-TSSSERASSPAQCVTPVQTVV 571
>gi|4557896 myotubularin [Homo sapiens]
Length = 603
Score = 728 bits (1878), Expect = 0.0
Identities = 353/606 (58%), Positives = 454/606 (74%), Gaps = 8/606 (1%)
Query: 61 LIAATISSQISGSVTSENVSRDYKALRDGNKLAQMEEAPLFPGESIKAIVKDVMYICPFM 120
+ +A+ S S S+ +E++ R RDG E P PGE++ K+V+YICPF
Sbjct: 1 MASASTSKYNSHSLENESIKR---TSRDGVNRDLTEAVPRLPGETL-ITDKEVIYICPFN 56
Query: 121 GAVSGTLTVTDFKLYFKNVERDPHFILDVPLGVISRVEKIG-AQSHGDNSCGIEIVCKDM 179
G + G + +T+++LY +++E D ILDVPLGVISR+EK+G A S G+NS G++I CKDM
Sbjct: 57 GPIKGRVYITNYRLYLRSLETDSSLILDVPLGVISRIEKMGGATSRGENSYGLDITCKDM 116
Query: 180 RNLRLAYKQEEQSKLGIFENLNKHAFPLSNGQALFAFSYKEKFPINGWKVYDPVSEYKRQ 239
RNLR A KQE S+ +FE L ++AFPL++ LFAF +EKF ++GW VY+PV EY+RQ
Sbjct: 117 RNLRFALKQEGHSRRDMFEILTRYAFPLAHSLPLFAFLNEEKFNVDGWTVYNPVEEYRRQ 176
Query: 240 GLPNESWKISKINSNYEFCDTYPAIIVVPTSVKDDDLSKVAAFRAKGRVPVLSWIHPESQ 299
GLPN W+I+ IN YE CDTYPA++VVP DDDL +VA FR++ R+PVLSWIHPE++
Sbjct: 177 GLPNHHWRITFINKCYELCDTYPALLVVPYRASDDDLRRVATFRSRNRIPVLSWIHPENK 236
Query: 300 ATITRCSQPLVGPNDKRCKEDEKYLQTIMDANAQSHKLIIFDARQNSVADTNKTKGGGYE 359
I RCSQPLVG + KR K+DEKYL I + N Q KL I+DAR + A NK GGGYE
Sbjct: 237 TVIVRCSQPLVGMSGKRNKDDEKYLDVIRETNKQISKLTIYDARPSVNAVANKATGGGYE 296
Query: 360 SESAYPNAELVFLEIHNIHVMRESLRKLKEIVYPSIDEARWLSNVDGTHWLEYIRMLLAG 419
S+ AY NAEL FL+IHNIHVMRESL+K+K+IVYP+++E+ WLS+++ THWLE+I+++L G
Sbjct: 297 SDDAYHNAELFFLDIHNIHVMRESLKKVKDIVYPNVEESHWLSSLESTHWLEHIKLVLTG 356
Query: 420 AVRIADKIESGKTSVVVHCSDGWDRTAQLTSLAMLMLDSYYRTIKGFETLVEKEWISFGH 479
A+++ADK+ SGK+SV+VHCSDGWDRTAQLTSLAMLMLDS+YR+I+GFE LV+KEWISFGH
Sbjct: 357 AIQVADKVSSGKSSVLVHCSDGWDRTAQLTSLAMLMLDSFYRSIEGFEILVQKEWISFGH 416
Query: 480 RFALRVGHGNDNHADADRSPIFLQFVDCVWQMTRQFPSAFEFNELFLITILDHLYSCLFG 539
+FA R+GHG+ NH DADRSPIFLQF+DCVWQM++QFP+AFEFNE FLI ILDHLYSC FG
Sbjct: 417 KFASRIGHGDKNHTDADRSPIFLQFIDCVWQMSKQFPTAFEFNEQFLIIILDHLYSCRFG 476
Query: 540 TFLCNCEQQRFKEDVYTKTISLWSYINSQLDEFSNPFFVNYENHVLYPVASLSHLELWVN 599
TFL NCE R ++ V +T+SLWS INS ++F NPF+ N VLYPVAS+ HLELWVN
Sbjct: 477 TFLFNCESARERQKVTERTVSLWSLINSNKEKFKNPFYTKEINRVLYPVASMRHLELWVN 536
Query: 600 YYVRWNPRMRPQM--PIHQNLKELLAVRAELQKRVEGLQREVATRAVSSSSERGSSPSHS 657
YY+RWNPR++ Q P+ Q ELLA+R E KR+E LQ + + +S SSPS
Sbjct: 537 YYIRWNPRIKQQQPNPVEQRYMELLALRDEYIKRLEELQLANSAK-LSDPPTSPSSPSQM 595
Query: 658 ATSVHT 663
V T
Sbjct: 596 MPHVQT 601
>gi|21361759 myotubularin related protein 8 [Homo sapiens]
Length = 704
Score = 358 bits (918), Expect = 1e-98
Identities = 199/505 (39%), Positives = 296/505 (58%), Gaps = 24/505 (4%)
Query: 149 VPLGVISRVEKIGAQSHGDNSCGIEIVCKDMRNLRLAYKQE---EQSKLGIFENLNKHAF 205
+ L I+ VEK+ S G C + + CK+ R + + + + + L++ A
Sbjct: 50 IALHHIATVEKLPITSLG---CPLTLRCKNFRVAHFVLDSDLVCHEVYISLLK-LSQPAL 105
Query: 206 PLSNGQALFAFSYKEK----FPINGWKVYDPVSEYKRQGLPNESWKISKINSNYEFCDTY 261
P + L+AFSY K +GWK+ DP+S++ R G+PN +W I+ N NYE C TY
Sbjct: 106 P----EDLYAFSYNPKSSKEMRESGWKLIDPISDFGRMGIPNRNWTITDANRNYEICSTY 161
Query: 262 PAIIVVPTSVKDDDLSKVAAFRAKGRVPVLSWIHPESQATITRCSQPLVGPNDKRCKEDE 321
P IVVP SV + + FR+K RVPVLS+++ E+ A I RCSQPL G RC +DE
Sbjct: 162 PPEIVVPKSVTLGTVVGSSKFRSKERVPVLSYLYKENNAAICRCSQPLSGFYT-RCVDDE 220
Query: 322 KYLQTIMDANAQSHKLIIFDARQNSVADTNKTKGGGYESESAYPNAELVFLEIHNIHVMR 381
L+ I N S + + D R A N+ G GYE+E Y N F+ I NIHVMR
Sbjct: 221 LLLEAISQTNPGSQFMYVVDTRPKLNAMANRAAGKGYENEDNYANIRFRFMGIENIHVMR 280
Query: 382 ESLRKLKEIVY---PSIDEARWLSNVDGTHWLEYIRMLLAGAVRIADKIESGKTSVVVHC 438
SL+KL E+ P++ E +LS ++ + WL +I+ ++ + I ++ K SV+VHC
Sbjct: 281 SSLQKLLEVCELKTPTMSE--FLSGLESSGWLRHIKAIMDAGIFITKAVKVEKASVLVHC 338
Query: 439 SDGWDRTAQLTSLAMLMLDSYYRTIKGFETLVEKEWISFGHRFALRVGHGNDNHADADRS 498
SDGWDRTAQ+ S+A ++LD +YRT KG L+EKEWIS GH+F+ R GH + + + S
Sbjct: 339 SDGWDRTAQVCSVASILLDPFYRTFKGLMILIEKEWISMGHKFSQRCGHLDGDSKEV--S 396
Query: 499 PIFLQFVDCVWQMTRQFPSAFEFNELFLITILDHLYSCLFGTFLCNCEQQRFKEDVYTKT 558
PIF QF+DC+WQ+ QFP AFEFNE FL+ I DH++SC FG FL NC++ R VY KT
Sbjct: 397 PIFTQFLDCIWQLMEQFPCAFEFNENFLLEIHDHVFSCQFGNFLGNCQKDREDLRVYEKT 456
Query: 559 ISLWSYINSQLDEFSNPFFVNYENH-VLYPVASLSHLELWVNYYVRWNPRMRPQMPIHQN 617
S+W ++ + +F NP + + + VL P +++ W Y R++ ++P+ + ++
Sbjct: 457 HSVWPFLVQRKPDFRNPLYKGFTMYGVLNPSTVPYNIQFWCGMYNRFDKGLQPKQSMLES 516
Query: 618 LKELLAVRAELQKRVEGLQREVATR 642
L E+ RA L+ V L++++ R
Sbjct: 517 LLEIKKQRAMLETDVHELEKKLKVR 541
>gi|134142348 myotubularin related protein 6 [Homo sapiens]
Length = 621
Score = 347 bits (891), Expect = 2e-95
Identities = 196/529 (37%), Positives = 302/529 (57%), Gaps = 20/529 (3%)
Query: 122 AVSGTLTVTDFKLYFKNVERDPHFILDVPLGVISRVEKIGAQSHGDNSCGIEIVCKDMRN 181
+++GTL +T L F + + +IL I+ VEK+ + G C + I CK+ R
Sbjct: 24 SLTGTLYLTATHLLFIDSHQKETWILHHH---IASVEKLALTTSG---CPLVIQCKNFRT 77
Query: 182 LRLAYKQEEQSKLGIFENLNKHAFPLSNGQALFAFSYKEKFP----INGWKVYDPVSEYK 237
+ +E I+ +L + + + + L+AFSY K + GW++ D EYK
Sbjct: 78 VHFIVPRERDCH-DIYNSLLQLS-KQAKYEDLYAFSYNPKQNDSERLQGWQLIDLAEEYK 135
Query: 238 RQGLPNESWKISKINSNYEFCDTYPAIIVVPTSVKDDDLSKVAAFRAKGRVPVLSWIHPE 297
R G+PN W++S N +Y+ C+TYP + VP + + FR+KGR PVLS+ H +
Sbjct: 136 RMGVPNSHWQLSDANRDYKICETYPRELYVPRIASKPIIVGSSKFRSKGRFPVLSYYHQD 195
Query: 298 SQATITRCSQPLVGPNDKRCKEDEKYLQTIMDANAQSHKLIIFDARQNSVADTNKTKGGG 357
+A I RCSQPL G + RC EDE LQ I AN + + + D R A N+ G G
Sbjct: 196 KEAAICRCSQPLSGFS-ARCLEDEHLLQAISKANPVNRYMYVMDTRPKLNAMANRAAGKG 254
Query: 358 YESESAYPNAELVFLEIHNIHVMRESLRKLKEIV-YPSIDEARWLSNVDGTHWLEYIRML 416
YE+E Y N F+ I NIHVMR SL+KL E+ + + S ++ + WL +I+ +
Sbjct: 255 YENEDNYSNIRFQFVGIENIHVMRSSLQKLLEVNGTKGLSVNDFYSGLESSGWLRHIKAV 314
Query: 417 LAGAVRIADKIESGKTSVVVHCSDGWDRTAQLTSLAMLMLDSYYRTIKGFETLVEKEWIS 476
+ A+ +A I SV+VHCSDGWDRT+Q+ SL L+LDSYYRTIKGF L+EK+WIS
Sbjct: 315 MDAAIFLAKAITVENASVLVHCSDGWDRTSQVCSLGSLLLDSYYRTIKGFMVLIEKDWIS 374
Query: 477 FGHRFALRVGHGNDNHADADRSPIFLQFVDCVWQMTRQFPSAFEFNELFLITILDHLYSC 536
FGH+F+ R G + + + SP+F QF++CVW +T QFP AFEF+E FL+ I +H++SC
Sbjct: 375 FGHKFSERCGQLDGDPKEV--SPVFTQFLECVWHLTEQFPQAFEFSEAFLLQIHEHIHSC 432
Query: 537 LFGTFLCNCEQQRFKEDVYTKTISLWSYINSQLDEFSNPFFVNYENH---VLYPVASLSH 593
FG FL NC+++R + + KT SLW ++ ++ NP + + E+H VL P +
Sbjct: 433 QFGNFLGNCQKEREELKLKEKTYSLWPFLLEDQKKYLNPLY-SSESHRFTVLEPNTVSFN 491
Query: 594 LELWVNYYVRWNPRMRPQMPIHQNLKELLAVRAELQKRVEGLQREVATR 642
+ W N Y +++ + P+ + + + +L+K ++ L+ ++ R
Sbjct: 492 FKFWRNMYHQFDRTLHPRQSVFNIIMNMNEQNKQLEKDIKDLESKIKQR 540
>gi|225543474 myotubularin related protein 7 [Homo sapiens]
Length = 660
Score = 329 bits (844), Expect = 4e-90
Identities = 196/557 (35%), Positives = 299/557 (53%), Gaps = 28/557 (5%)
Query: 122 AVSGTLTVTDFKLYFKNVERDPHFILDVPLGVISRVEKIGAQSHGDNSCGIEIVCKDMRN 181
A GTL +T + F DP + IS +EK + G C + I CK+ +
Sbjct: 23 AALGTLYLTATHVIFVENSPDPRKETWILHSQISTIEKQATTATG---CPLLIRCKNFQI 79
Query: 182 LRLAYKQEEQSKLGIFENLNKHAFPLSNGQALFAFSYKEKFPIN----GWKVYDPVSEYK 237
++L QE ++ +L + A P+ + L+ FS+ GW + D EY
Sbjct: 80 IQLIIPQERDCH-DVYISLIRLARPVKY-EELYCFSFNPMLDKEEREQGWVLIDLSEEYT 137
Query: 238 RQGLPNESWKISKINSNYEFCDTYPAIIVVPTSVKDDDLSKVAAFRAKGRVPVLSWIHPE 297
R GLPN W++S +N +Y CD+YP + VP S + + FR++ R PVLS+ + +
Sbjct: 138 RMGLPNHYWQLSDVNRDYRVCDSYPTELYVPKSATAHIIVGSSKFRSRRRFPVLSYYYKD 197
Query: 298 SQATITRCSQPLVGPNDKRCKEDEKYLQTIMDANAQSHKLIIFDARQNSVADTNKTKGGG 357
+ A+I R SQPL G + RC EDE+ LQ I AN S + + D R A N+ G G
Sbjct: 198 NHASICRSSQPLSGFS-ARCLEDEQMLQAIRKANPGSDFVYVVDTRPKLNAMANRAAGKG 256
Query: 358 YESESAYPNAELVFLEIHNIHVMRESLRKLKEIVY---PSIDEARWLSNVDGTHWLEYIR 414
YE+E Y N + F+ I NIHVMR SL+K+ E+ PS+ + W ++ + WL +I+
Sbjct: 257 YENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCELKSPSMSDFLW--GLENSGWLRHIK 314
Query: 415 MLLAGAVRIADKIESGKTSVVVHCSDGWDRTAQLTSLAMLMLDSYYRTIKGFETLVEKEW 474
++ + IA + SV+VHCSDGWDRTAQ+ S+A L+LD +YRT+KGF L+EK+W
Sbjct: 315 AIMDAGIFIAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPHYRTLKGFMVLIEKDW 374
Query: 475 ISFGHRFALRVGHGNDNHADADRSPIFLQFVDCVWQMTRQFPSAFEFNELFLITILDHLY 534
ISFGH+F R +GN + + SP+ QF++CVWQ+ QFP AFEFNE FLI I H+Y
Sbjct: 375 ISFGHKFNHR--YGNLDGDPKEISPVIDQFIECVWQLMEQFPCAFEFNERFLIHIQHHIY 432
Query: 535 SCLFGTFLCNCEQQRFKEDVYTKTISLWSYINSQLDEFSNPFF----VNYENHVLYPVAS 590
SC FG FLCN +++R + + +T SLW+++ ++ NP F + + P
Sbjct: 433 SCQFGNFLCNSQKERRELKIQERTYSLWAHLWKNRADYLNPLFRADHSQTQGTLHLPTTP 492
Query: 591 LSHL-ELWVNYYVRWNPRMRPQMPIHQNLKELLAVRAELQKRVEGLQ------REVATRA 643
+ + + W Y R+ M+P+ + L + +L++ +E L+ ++V
Sbjct: 493 CNFMYKFWSGMYNRFEKGMQPRQSVTDYLMAVKEETQQLEEELEALEERLEKIQKVQLNC 552
Query: 644 VSSSSERGSSPSHSATS 660
S++ HS S
Sbjct: 553 TKVKSKQSEPSKHSGFS 569
>gi|19923424 myotubularin related protein 9 [Homo sapiens]
Length = 549
Score = 324 bits (831), Expect = 1e-88
Identities = 193/537 (35%), Positives = 292/537 (54%), Gaps = 17/537 (3%)
Query: 110 VKDVMYICPFMGAVSGTLTVTDFKLYFKNVERDPHFILDVPLGVISRVEKIGAQSHGDNS 169
V +V+ PF AV GTL +T L + +D L + I ++K S G
Sbjct: 12 VDNVVLHRPFYPAVEGTLCLTGHHLILSS-RQDNTEELWLLHSNIDAIDKRFVGSLGT-- 68
Query: 170 CGIEIVCKDMRNLRLAYKQEEQSKLGIFENLNKHAFPLSNGQALFAFSYKEKFPI--NGW 227
I I CKD R ++L E+ L I ++ + L + ++ F Y+ F + +GW
Sbjct: 69 --IIIKCKDFRIIQLDIPGMEEC-LNIASSIEALS-TLDSITLMYPFFYRPMFEVIEDGW 124
Query: 228 KVYDPVSEYKRQGLPNESWKISKINSNYEFCDTYPAIIVVPTSVKDDDLSKVAAFRAKGR 287
+ P E++ W++S +N + C +YP I+ VP S+ D+ L KVA FR GR
Sbjct: 125 HSFLPEQEFELYSSATSEWRLSYVNKEFAVCPSYPPIVTVPKSIDDEALRKVATFRHGGR 184
Query: 288 VPVLSWIHPESQATITRCSQPLVGPNDKRCKEDEKYLQTIMDANAQSHKLIIFDARQNSV 347
PVLS+ H ++ I R QPL G N +RCKEDEK + + A + + I D R +V
Sbjct: 185 FPVLSYYHKKNGMVIMRSGQPLTGTNGRRCKEDEKLINATLRAGKRGY---IIDTRSLNV 241
Query: 348 ADTNKTKGGGYESESAYPNAELVFLEIHNIHVMRESLRKLKEIVYPSIDEA-RWLSNVDG 406
A + KGGG+E E+ YP + I H+++ESL KL E RWLS ++
Sbjct: 242 AQQTRAKGGGFEQEAHYPQWRRIHKSIERYHILQESLIKLVEACNDQTHNMDRWLSKLEA 301
Query: 407 THWLEYIRMLLAGAVRIADKIESGKTSVVVHCSDGWDRTAQLTSLAMLMLDSYYRTIKGF 466
++WL +I+ +L A A I+ S+++H ++G D T Q+TSLA ++L+ RTI+GF
Sbjct: 302 SNWLTHIKEILTTACLAAQCIDREGASILIHGTEGTDSTLQVTSLAQIILEPRSRTIRGF 361
Query: 467 ETLVEKEWISFGHRFALRVGH-GNDNHADADRSPIFLQFVDCVWQMTRQFPSAFEFNELF 525
E L+E+EW+ GH F R N +P+FL F+DCVWQ+ RQFP +FEFNE F
Sbjct: 362 EALIEREWLQAGHPFQQRCAQSAYCNTKQKWEAPVFLLFLDCVWQILRQFPCSFEFNENF 421
Query: 526 LITILDHLYSCLFGTFLCNCEQQRFKEDVYTKTISLWSYIN--SQLDEFSNPFFVNYENH 583
LI + +H Y+ FGTFL N E +R K + KT+SLWS++N S+L +F+NP F N
Sbjct: 422 LIMLFEHAYASQFGTFLGNNESERCKLKLQQKTMSLWSWVNQPSELSKFTNPLF-EANNL 480
Query: 584 VLYPVASLSHLELWVNYYVRWNPRMRPQMPIHQNLKELLAVRAELQKRVEGLQREVA 640
V++P + L LW ++RWN + ++ + ++ ELQ +V L+R++A
Sbjct: 481 VIWPSVAPQSLPLWEGIFLRWNRSSKYLDEAYEEMVNIIEYNKELQAKVNILRRQLA 537
>gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens]
Length = 1161
Score = 317 bits (811), Expect = 3e-86
Identities = 189/564 (33%), Positives = 290/564 (51%), Gaps = 89/564 (15%)
Query: 119 FMG-AVSGTLTVTDFKLYFKNVERDPHFILDVPLGVISRVEKIGAQSHGDNSCGIEIVCK 177
F+G A + +++++L+ K E +++VPL +I VE + + + CK
Sbjct: 44 FVGRAEDAIIALSNYRLHIKFKES----LVNVPLQLIESVEC-------RDIFQLHLTCK 92
Query: 178 DMRNLRLAYKQEEQSKLGIFENLNKHAFPLSNGQALFAFSYKEKFPINGW--KVYDPV-- 233
D + +R + EQ + + + LN P + + LF+F+Y + W +VY
Sbjct: 93 DCKVIRCQFSTFEQCQEWL-KRLNNAIRPPAKIEDLFSFAY------HAWCMEVYASEKE 145
Query: 234 -----------------SEYKRQGLP-NESWKISKINSNYEFCDTYPAIIVVPTSVKDDD 275
+E +R G N +W+IS IN Y+ C +YP ++VP + D +
Sbjct: 146 QHGDLCRPGEHVTSRFKNEVERMGFDMNNAWRISNINEKYKLCGSYPQELIVPAWITDKE 205
Query: 276 LSKVAAFRAKGRVPVLSWIHPESQATITRCSQPLVGPNDKRCKEDEKYLQTIMDANA--- 332
L V++FR+ R+P + + H + A I RC QP V R +DE +Q++ A A
Sbjct: 206 LESVSSFRSWKRIPAVIYRHQSNGAVIARCGQPEVSWWGWRNADDEHLVQSVAKACASDS 265
Query: 333 ------------------------------------------QSHKLIIFDARQNSVADT 350
Q KL+I DAR + A
Sbjct: 266 RSSGSKLSTRNTSRDFPNGGDLSDVEFDSSLSNASGAESLAIQPQKLLILDARSYAAAVA 325
Query: 351 NKTKGGGYESESAYPNAELVFLEIHNIHVMRESLRKLKEIVYPSIDEARWLSNVDGTHWL 410
N+ KGGG E YPN E+VF+ + NIH +R S + L+ + D WLS ++ T WL
Sbjct: 326 NRAKGGGCECPEYYPNCEVVFMGMANIHSIRRSFQSLRLLCTQMPDPGNWLSALESTKWL 385
Query: 411 EYIRMLLAGAVRIADKIESGKTSVVVHCSDGWDRTAQLTSLAMLMLDSYYRTIKGFETLV 470
++ +LL A+ + ++ + V+VHCSDGWDRT Q+ +LA L+LD YYRTI+GF+ LV
Sbjct: 386 HHLSVLLKSALLVVHAVDQDQRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLV 445
Query: 471 EKEWISFGHRFALRVGHGNDNHADADRSPIFLQFVDCVWQMTRQFPSAFEFNELFLITIL 530
E EW+ FGH+FA R GHG ++ +R P+FLQ++DCV Q+ RQFP +FEFNE FL+ ++
Sbjct: 446 EMEWLDFGHKFADRCGHGENSDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLV 505
Query: 531 DHLYSCLFGTFLCNCEQQRFKEDVYTKTISLWSYINSQLDEFSNPFFVNYENHVLYPVAS 590
H YSCLFGTFLCN ++R ++ +T S+WS + + F N + + VLYPV
Sbjct: 506 QHTYSCLFGTFLCNNAKERGEKHTQERTCSVWSLLRAGNKAFKNLLYSSQSEAVLYPVCH 565
Query: 591 LSHLELWVNYYVRWNPRMRPQMPI 614
+ +L LW Y+ P P P+
Sbjct: 566 VRNLMLWSAVYL---PCPSPTTPV 586
>gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens]
Length = 1170
Score = 317 bits (811), Expect = 3e-86
Identities = 189/564 (33%), Positives = 290/564 (51%), Gaps = 89/564 (15%)
Query: 119 FMG-AVSGTLTVTDFKLYFKNVERDPHFILDVPLGVISRVEKIGAQSHGDNSCGIEIVCK 177
F+G A + +++++L+ K E +++VPL +I VE + + + CK
Sbjct: 44 FVGRAEDAIIALSNYRLHIKFKES----LVNVPLQLIESVEC-------RDIFQLHLTCK 92
Query: 178 DMRNLRLAYKQEEQSKLGIFENLNKHAFPLSNGQALFAFSYKEKFPINGW--KVYDPV-- 233
D + +R + EQ + + + LN P + + LF+F+Y + W +VY
Sbjct: 93 DCKVIRCQFSTFEQCQEWL-KRLNNAIRPPAKIEDLFSFAY------HAWCMEVYASEKE 145
Query: 234 -----------------SEYKRQGLP-NESWKISKINSNYEFCDTYPAIIVVPTSVKDDD 275
+E +R G N +W+IS IN Y+ C +YP ++VP + D +
Sbjct: 146 QHGDLCRPGEHVTSRFKNEVERMGFDMNNAWRISNINEKYKLCGSYPQELIVPAWITDKE 205
Query: 276 LSKVAAFRAKGRVPVLSWIHPESQATITRCSQPLVGPNDKRCKEDEKYLQTIMDANA--- 332
L V++FR+ R+P + + H + A I RC QP V R +DE +Q++ A A
Sbjct: 206 LESVSSFRSWKRIPAVIYRHQSNGAVIARCGQPEVSWWGWRNADDEHLVQSVAKACASDS 265
Query: 333 ------------------------------------------QSHKLIIFDARQNSVADT 350
Q KL+I DAR + A
Sbjct: 266 RSSGSKLSTRNTSRDFPNGGDLSDVEFDSSLSNASGAESLAIQPQKLLILDARSYAAAVA 325
Query: 351 NKTKGGGYESESAYPNAELVFLEIHNIHVMRESLRKLKEIVYPSIDEARWLSNVDGTHWL 410
N+ KGGG E YPN E+VF+ + NIH +R S + L+ + D WLS ++ T WL
Sbjct: 326 NRAKGGGCECPEYYPNCEVVFMGMANIHSIRRSFQSLRLLCTQMPDPGNWLSALESTKWL 385
Query: 411 EYIRMLLAGAVRIADKIESGKTSVVVHCSDGWDRTAQLTSLAMLMLDSYYRTIKGFETLV 470
++ +LL A+ + ++ + V+VHCSDGWDRT Q+ +LA L+LD YYRTI+GF+ LV
Sbjct: 386 HHLSVLLKSALLVVHAVDQDQRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLV 445
Query: 471 EKEWISFGHRFALRVGHGNDNHADADRSPIFLQFVDCVWQMTRQFPSAFEFNELFLITIL 530
E EW+ FGH+FA R GHG ++ +R P+FLQ++DCV Q+ RQFP +FEFNE FL+ ++
Sbjct: 446 EMEWLDFGHKFADRCGHGENSDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLV 505
Query: 531 DHLYSCLFGTFLCNCEQQRFKEDVYTKTISLWSYINSQLDEFSNPFFVNYENHVLYPVAS 590
H YSCLFGTFLCN ++R ++ +T S+WS + + F N + + VLYPV
Sbjct: 506 QHTYSCLFGTFLCNNAKERGEKHTQERTCSVWSLLRAGNKAFKNLLYSSQSEAVLYPVCH 565
Query: 591 LSHLELWVNYYVRWNPRMRPQMPI 614
+ +L LW Y+ P P P+
Sbjct: 566 VRNLMLWSAVYL---PCPSPTTPV 586
>gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens]
Length = 1198
Score = 317 bits (811), Expect = 3e-86
Identities = 189/564 (33%), Positives = 290/564 (51%), Gaps = 89/564 (15%)
Query: 119 FMG-AVSGTLTVTDFKLYFKNVERDPHFILDVPLGVISRVEKIGAQSHGDNSCGIEIVCK 177
F+G A + +++++L+ K E +++VPL +I VE + + + CK
Sbjct: 44 FVGRAEDAIIALSNYRLHIKFKES----LVNVPLQLIESVEC-------RDIFQLHLTCK 92
Query: 178 DMRNLRLAYKQEEQSKLGIFENLNKHAFPLSNGQALFAFSYKEKFPINGW--KVYDPV-- 233
D + +R + EQ + + + LN P + + LF+F+Y + W +VY
Sbjct: 93 DCKVIRCQFSTFEQCQEWL-KRLNNAIRPPAKIEDLFSFAY------HAWCMEVYASEKE 145
Query: 234 -----------------SEYKRQGLP-NESWKISKINSNYEFCDTYPAIIVVPTSVKDDD 275
+E +R G N +W+IS IN Y+ C +YP ++VP + D +
Sbjct: 146 QHGDLCRPGEHVTSRFKNEVERMGFDMNNAWRISNINEKYKLCGSYPQELIVPAWITDKE 205
Query: 276 LSKVAAFRAKGRVPVLSWIHPESQATITRCSQPLVGPNDKRCKEDEKYLQTIMDANA--- 332
L V++FR+ R+P + + H + A I RC QP V R +DE +Q++ A A
Sbjct: 206 LESVSSFRSWKRIPAVIYRHQSNGAVIARCGQPEVSWWGWRNADDEHLVQSVAKACASDS 265
Query: 333 ------------------------------------------QSHKLIIFDARQNSVADT 350
Q KL+I DAR + A
Sbjct: 266 RSSGSKLSTRNTSRDFPNGGDLSDVEFDSSLSNASGAESLAIQPQKLLILDARSYAAAVA 325
Query: 351 NKTKGGGYESESAYPNAELVFLEIHNIHVMRESLRKLKEIVYPSIDEARWLSNVDGTHWL 410
N+ KGGG E YPN E+VF+ + NIH +R S + L+ + D WLS ++ T WL
Sbjct: 326 NRAKGGGCECPEYYPNCEVVFMGMANIHSIRRSFQSLRLLCTQMPDPGNWLSALESTKWL 385
Query: 411 EYIRMLLAGAVRIADKIESGKTSVVVHCSDGWDRTAQLTSLAMLMLDSYYRTIKGFETLV 470
++ +LL A+ + ++ + V+VHCSDGWDRT Q+ +LA L+LD YYRTI+GF+ LV
Sbjct: 386 HHLSVLLKSALLVVHAVDQDQRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLV 445
Query: 471 EKEWISFGHRFALRVGHGNDNHADADRSPIFLQFVDCVWQMTRQFPSAFEFNELFLITIL 530
E EW+ FGH+FA R GHG ++ +R P+FLQ++DCV Q+ RQFP +FEFNE FL+ ++
Sbjct: 446 EMEWLDFGHKFADRCGHGENSDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLV 505
Query: 531 DHLYSCLFGTFLCNCEQQRFKEDVYTKTISLWSYINSQLDEFSNPFFVNYENHVLYPVAS 590
H YSCLFGTFLCN ++R ++ +T S+WS + + F N + + VLYPV
Sbjct: 506 QHTYSCLFGTFLCNNAKERGEKHTQERTCSVWSLLRAGNKAFKNLLYSSQSEAVLYPVCH 565
Query: 591 LSHLELWVNYYVRWNPRMRPQMPI 614
+ +L LW Y+ P P P+
Sbjct: 566 VRNLMLWSAVYL---PCPSPTTPV 586
>gi|217272865 myotubularin related protein 4 [Homo sapiens]
Length = 1195
Score = 303 bits (776), Expect = 3e-82
Identities = 181/568 (31%), Positives = 297/568 (52%), Gaps = 71/568 (12%)
Query: 119 FMG-AVSGTLTVTDFKLYFKNVERDPHFILDVPLGVISRVEKIGAQSHGDNSCGIEIVCK 177
F+G A + +++++L+ K + +++VPL +I VE + + I CK
Sbjct: 44 FLGRAADALIAISNYRLHIKFKDS----VINVPLRMIDSVES-------RDMFQLHISCK 92
Query: 178 DMRNLRLAYKQEEQSKLGIFENLNKHAFPLSNGQALFAFSY--------KEKFPINGWKV 229
D + +R + +Q + + A P + + LFAF+Y +E + +
Sbjct: 93 DSKVVRCHFSTFKQCQEWLSRLSRATARP-AKPEDLFAFAYHAWCLGLTEEDQHTHLCQP 151
Query: 230 YDPV-----SEYKRQGLPNES-WKISKINSNYEFCDTYPAIIVVPTSVKDDDLSKVAAFR 283
+ + +E R G ++ W++S INSNY+ C +YP ++VP + D +L VA+FR
Sbjct: 152 GEHIRCRQEAELARMGFDLQNVWRVSHINSNYKLCPSYPQKLLVPVWITDKELENVASFR 211
Query: 284 AKGRVPVLSWIHPESQATITRCSQPLVGPNDKRCKEDEKYLQTI---------------- 327
+ R+PV+ + H + A I RCSQP + R +DE + +I
Sbjct: 212 SWKRIPVVVYRHLRNGAAIARCSQPEISWWGWRNADDEYLVTSIAKACALDPGTRATGGS 271
Query: 328 -------------------------MDANAQSHKLIIFDARQNSVADTNKTKGGGYESES 362
+++ A KL+I DAR + A N+ KGGG E E
Sbjct: 272 LSTGNNDTSEACDADFDSSLTACSGVESTAAPQKLLILDARSYTAAVANRAKGGGCECEE 331
Query: 363 AYPNAELVFLEIHNIHVMRESLRKLKEIVYPSIDEARWLSNVDGTHWLEYIRMLLAGAVR 422
YPN E+VF+ + NIH +R S + L+ + D + WLS ++ T WL+++ ++L AV
Sbjct: 332 YYPNCEVVFMGMANIHAIRNSFQYLRAVCSQMPDPSNWLSALESTKWLQHLSVMLKAAVL 391
Query: 423 IADKIESGKTSVVVHCSDGWDRTAQLTSLAMLMLDSYYRTIKGFETLVEKEWISFGHRFA 482
+A+ ++ V+VHCSDGWDRT Q+ +LA ++LD YYRT++GF+ LVE +W+ FGH+F
Sbjct: 392 VANTVDREGRPVLVHCSDGWDRTPQIVALAKILLDPYYRTLEGFQVLVESDWLDFGHKFG 451
Query: 483 LRVGHGNDNHADADRSPIFLQFVDCVWQMTRQFPSAFEFNELFLITILDHLYSCLFGTFL 542
R GH + ++ P+FLQ++D V Q+ +QFP FEFNE FL+ ++ H YSCL+GTFL
Sbjct: 452 DRCGHQENVEDQNEQCPVFLQWLDSVHQLLKQFPCLFEFNEAFLVKLVQHTYSCLYGTFL 511
Query: 543 CNCEQQRFKEDVYTKTISLWSYINSQLDEFSNPFFVNYENHVLYPVASLSHLELWVNYYV 602
N +R K ++Y +T S+W+ + + F N + + VL+PV + L LW Y+
Sbjct: 512 ANNPCEREKRNIYKRTCSVWALLRAGNKNFHNFLYTPSSDMVLHPVCHVRALHLWTAVYL 571
Query: 603 RWNPRMRPQMPIHQNLKELLAVRAELQK 630
P P +N+ L+ A+ Q+
Sbjct: 572 ---PASSPCTLGEENMDLYLSPVAQSQE 596
>gi|124028527 myotubularin related protein 10 [Homo sapiens]
Length = 777
Score = 159 bits (402), Expect = 8e-39
Identities = 142/513 (27%), Positives = 215/513 (41%), Gaps = 108/513 (21%)
Query: 133 KLYFKNVERDPHFILDVPLGVISRVEKIGAQSHGDNSCG-----------IEIVCKDMRN 181
K +++N+ H DVPL I ++ + G + I CKD R
Sbjct: 87 KFHYRNLLLGEH---DVPLTCIEQIVTVNDHKRKQKVLGPNQKLKFNPTELIIYCKDFRI 143
Query: 182 LRLAYKQEEQSKLGIFENLNKHAFPLSNGQALFAFSYKEKF------PING--------- 226
+R + + H ++ Q LFAF Y K ING
Sbjct: 144 VRFRFDESGPESAKKVCLAIAHYSQPTDLQLLFAFEYVGKKYHNSANKINGIPSGDGGGG 203
Query: 227 -----------------WKVY-DPVSEYKRQGLPNESWKISKINSNYEFCDTYPAIIVVP 268
++ Y D E KR G W++ IN Y P IVVP
Sbjct: 204 GGGGNGAGGGSSQKTPLFETYSDWDREIKRTGA--SGWRVCSINEGYMISTCLPEYIVVP 261
Query: 269 TSVKDDDLSKVAAFRAKGRVPVLSWIHPESQATITRCSQPLVGPNDKRCKEDEKYLQTIM 328
+S+ D DL + R+P+ W H A + L+ K + K Q I
Sbjct: 262 SSLADQDLKIFSHSFVGRRMPLWCWSHSNGSALVRMA---LI----KDVLQQRKIDQRIC 314
Query: 329 DANAQSHKLIIFDARQNSV--ADTNKTKGGGYESESAYPNAELVFLEIHNIHVMRESLRK 386
+A +SH +++ V +D +KT + NI ++ + K
Sbjct: 315 NAITKSHP------QRSDVYKSDLDKT--------------------LPNIQEVQAAFVK 348
Query: 387 LKEIVYPSI---DEARWLSNVDGTHWLEYIRMLLAGAVRIADKIESGKTSVVVHCSDGWD 443
LK++ E +WLS+++ T WLEY+R L + + +ES SVV+ +G D
Sbjct: 349 LKQLCVNEPFEETEEKWLSSLENTRWLEYVRAFLKHSAELVYMLESKHLSVVLQEEEGRD 408
Query: 444 RTAQLTSLAMLMLDSYYRTIKGFETLVEKEWISFGHRFALRVGHGNDNHADADRSPIFLQ 503
+ + SL +MLD Y+RTI GF++L++KEW+ G++F R H + + SP+FL
Sbjct: 409 LSCCVASLVQVMLDPYFRTITGFQSLIQKEWVMAGYQFLDRCNHLKRSEKE---SPLFLL 465
Query: 504 FVDCVWQMTRQFPSAFEFNELFLITILDHLYSCLFGTFLCNCEQQRFK---EDVYTKTIS 560
F+D WQ+ Q+P+AFEF+E +L + D LFGTFL N QR K E +K I
Sbjct: 466 FLDATWQLLEQYPAAFEFSETYLAVLYDSTRISLFGTFLFNSPHQRVKQSTEFAISKNIQ 525
Query: 561 L-------------WSYINSQLDE--FSNPFFV 578
L WS + D F NPF++
Sbjct: 526 LGDEKGLKFPSVWDWSLQFTAKDRTLFHNPFYI 558
>gi|29788755 SET binding factor 2 [Homo sapiens]
Length = 1849
Score = 143 bits (360), Expect = 6e-34
Identities = 89/255 (34%), Positives = 138/255 (54%), Gaps = 23/255 (9%)
Query: 366 NAELVFLEIHNIHVMRESLRKLKEIVYPSI----DEARWLSNVDGTHWLEYIRMLLAGAV 421
N E V +E H I ++ S +KL PS E +L + + W + ++ AV
Sbjct: 1335 NCEFVPVEFHEIRQVKASFKKLMRACIPSTIPTDSEVTFLKALGDSEWFPQLHRIMQLAV 1394
Query: 422 RIADKIESGKTSVVVHCSDGWDRTAQLTSLAMLMLDSYYRTIKGFETLVEKEWISFGHRF 481
+++ +E+G +SV+V +GWD TAQ+TSL L+ D +YRT++GF+ LVEKEW+SFGH+F
Sbjct: 1395 VVSEVLENG-SSVLVCLEEGWDITAQVTSLVQLLSDPFYRTLEGFQMLVEKEWLSFGHKF 1453
Query: 482 ALRVGHGNDNHADADRSPIFLQFVDCVWQMTRQFPSAFEFNELFLITILDHLYSCLFGTF 541
+ R N + +P+FLQF+DCV Q+ Q+P+ FEFN +L + H S F TF
Sbjct: 1454 SQR-SSLTLNCQGSGFAPVFLQFLDCVHQVHNQYPTEFEFNLYYLKFLAFHYVSNRFKTF 1512
Query: 542 LCNCEQQRFK---------EDVYTKTISLWSYINSQLDEFSNPFFVNY-----ENHVLYP 587
L + + +R + E K + +W I+ +P F NY E L P
Sbjct: 1513 LLDSDYERLEHGTLFDDKGEKHAKKGVCIWECIDRM--HKRSPIFFNYLYSPLEIEALKP 1570
Query: 588 VASLSHLELWVNYYV 602
++S L+ W +YY+
Sbjct: 1571 NVNVSSLKKW-DYYI 1584
Score = 50.1 bits (118), Expect = 7e-06
Identities = 32/113 (28%), Positives = 50/113 (44%), Gaps = 19/113 (16%)
Query: 244 ESWKISKINSNYEFCDTYPAIIVVPTSVKDDDLSKVAAFRAKGRVPVLSWIHPESQATIT 303
E ++I+ N Y C +YP ++VVP +V+D L +VA R+PV+ W + S +
Sbjct: 1136 EYFRITASNRMYSLCRSYPGLLVVPQAVQDSSLPRVARCYRHNRLPVVCWKNSRSGTLLL 1195
Query: 304 RC---------------SQPLVGP----NDKRCKEDEKYLQTIMDANAQSHKL 337
R + P P E EKYLQ +++A + KL
Sbjct: 1196 RSGGFHGKGVVGLFKSQNSPQAAPTSSLESSSSIEQEKYLQALLNAVSVHQKL 1248
>gi|239735519 SET binding factor 1 [Homo sapiens]
Length = 1893
Score = 139 bits (351), Expect = 6e-33
Identities = 85/251 (33%), Positives = 137/251 (54%), Gaps = 20/251 (7%)
Query: 368 ELVFLEIHNIHVMRESLRKLKEIVYPSIDEAR-----WLSNVDGTHWLEYIRMLLAGAVR 422
ELV +E+ ++ S +KL + P A +L +++ + WL I LL +V
Sbjct: 1373 ELVPIEVFEARQVKASFKKLLKACVPGCPAAEPSPASFLRSLEDSEWLIQIHKLLQVSVL 1432
Query: 423 IADKIESGKTSVVVHCSDGWDRTAQLTSLAMLMLDSYYRTIKGFETLVEKEWISFGHRFA 482
+ + ++SG +SV+V DGWD T Q+ SL L+ D +YRT++GF LVEKEW+SFGHRF+
Sbjct: 1433 VVELLDSG-SSVLVGLEDGWDITTQVVSLVQLLSDPFYRTLEGFRLLVEKEWLSFGHRFS 1491
Query: 483 LRVGHGNDNHADADRSPIFLQFVDCVWQMTRQFPSAFEFNELFLITILDHLYSCLFGTFL 542
R H + + +P+FLQF+DCV Q+ QFP FEF++ +L + H S F TFL
Sbjct: 1492 HRGAHTLAGQS-SGFTPVFLQFLDCVHQVHLQFPMEFEFSQFYLKFLGYHHVSRRFRTFL 1550
Query: 543 CNCEQQRFKEDV----------YTKTISLWSYI---NSQLDEFSNPFFVNYENHVLYPVA 589
+ + +R + + S+W Y+ + + F N + + VL P +
Sbjct: 1551 LDSDYERIELGLLYEEKGERRGQVPCRSVWEYVDRLSKRTPVFHNYMYAPEDAEVLRPYS 1610
Query: 590 SLSHLELWVNY 600
++S+L++W Y
Sbjct: 1611 NVSNLKVWDFY 1621
Score = 54.3 bits (129), Expect = 4e-07
Identities = 34/123 (27%), Positives = 55/123 (44%), Gaps = 27/123 (21%)
Query: 235 EYKRQGL----------PNESWKISKINSNYEFCDTYPAIIVVPTSVKDDDLSKVAAFRA 284
+Y+R GL +E ++IS +N Y C +YP +++VP SV+D+ L +V+
Sbjct: 1129 DYQRLGLGTLSSSLSRAKSEPFRISPVNRMYAICRSYPGLLIVPQSVQDNALQRVSRCYR 1188
Query: 285 KGRVPVLSWIHPESQATITR-----------------CSQPLVGPNDKRCKEDEKYLQTI 327
+ R PV+ W S+A + R P D E EKYLQ +
Sbjct: 1189 QNRFPVVCWRSGRSKAVLLRSGGLHGKGVVGLFKAQNAPSPGQSQADSSSLEQEKYLQAV 1248
Query: 328 MDA 330
+ +
Sbjct: 1249 VSS 1251
>gi|224994251 myotubularin related protein 11 isoform a [Homo
sapiens]
Length = 709
Score = 137 bits (345), Expect = 3e-32
Identities = 104/370 (28%), Positives = 169/370 (45%), Gaps = 68/370 (18%)
Query: 235 EYKRQGLPNESWKISKINSNYEFCDTYPAIIVVPTSVKDDDLSKVAAFRAKGRVPVLSWI 294
E +R+ W++S +N ++ + P VP + D ++ + +GR P LSW
Sbjct: 203 ETERKKQAARGWRVSTVNERFDVATSLPRYFWVPNRILDSEVRRAFGHFHQGRGPRLSWH 262
Query: 295 HPESQATITRCS--QPLVGPNDKRCKEDEKYLQTIMDANAQSHKLIIFDARQNSVADTNK 352
HP + + RC PN KED + ++ ++ A L+ S+AD
Sbjct: 263 HP-GGSDLLRCGGFYTASDPN----KEDIRAVELMLQAGHSDVVLVDTMDELPSLAD--- 314
Query: 353 TKGGGYESESAYPNAELVFLEIHNIHVMRESLRKLKEIVYP--SIDEARWLSNVDGTHWL 410
+L L +L+ + P S+ E +WLS ++GT WL
Sbjct: 315 --------------VQLAHL-------------RLRALCLPDSSVAEDKWLSALEGTRWL 347
Query: 411 EYIRMLLAGAVRIADKIESGKTSVVVHCSDGWDRTAQLTSLAMLMLDSYYRTIKGFETLV 470
+Y+R L A I+ + S SV++ D L+SL L+ RT+ GF++LV
Sbjct: 348 DYVRACLRKASDISVLVTSRVRSVILQERGDRDLNGLLSSLVQLLSAPEARTLFGFQSLV 407
Query: 471 EKEWISFGHRFALRVGHGNDNHADADRSPIFLQFVDCVWQMTRQFPSAFEFNELFLITIL 530
++EW++ GH F R+G ++ +P+FL F+DCVWQ+ +QFP+ FEF+E FL+ +
Sbjct: 408 QREWVAAGHPFLTRLG----GTGASEEAPVFLLFLDCVWQLLQQFPADFEFSEFFLLALH 463
Query: 531 DHLYSCLFGTFLCNCEQQRFKE--------DVYTK-------------TISLWS----YI 565
D + TFL N +R K+ VYT +S+W Y
Sbjct: 464 DSVRVPDTLTFLRNTPWERGKQSGQLNSYTQVYTPGYSQPPAGNSFNLQLSVWDWDLRYS 523
Query: 566 NSQLDEFSNP 575
N+Q+ +F NP
Sbjct: 524 NAQILQFQNP 533
>gi|89111941 myotubularin related protein 11 isoform b [Homo
sapiens]
Length = 640
Score = 137 bits (345), Expect = 3e-32
Identities = 104/370 (28%), Positives = 169/370 (45%), Gaps = 68/370 (18%)
Query: 235 EYKRQGLPNESWKISKINSNYEFCDTYPAIIVVPTSVKDDDLSKVAAFRAKGRVPVLSWI 294
E +R+ W++S +N ++ + P VP + D ++ + +GR P LSW
Sbjct: 131 ETERKKQAARGWRVSTVNERFDVATSLPRYFWVPNRILDSEVRRAFGHFHQGRGPRLSWH 190
Query: 295 HPESQATITRCS--QPLVGPNDKRCKEDEKYLQTIMDANAQSHKLIIFDARQNSVADTNK 352
HP + + RC PN KED + ++ ++ A L+ S+AD
Sbjct: 191 HP-GGSDLLRCGGFYTASDPN----KEDIRAVELMLQAGHSDVVLVDTMDELPSLAD--- 242
Query: 353 TKGGGYESESAYPNAELVFLEIHNIHVMRESLRKLKEIVYP--SIDEARWLSNVDGTHWL 410
+L L +L+ + P S+ E +WLS ++GT WL
Sbjct: 243 --------------VQLAHL-------------RLRALCLPDSSVAEDKWLSALEGTRWL 275
Query: 411 EYIRMLLAGAVRIADKIESGKTSVVVHCSDGWDRTAQLTSLAMLMLDSYYRTIKGFETLV 470
+Y+R L A I+ + S SV++ D L+SL L+ RT+ GF++LV
Sbjct: 276 DYVRACLRKASDISVLVTSRVRSVILQERGDRDLNGLLSSLVQLLSAPEARTLFGFQSLV 335
Query: 471 EKEWISFGHRFALRVGHGNDNHADADRSPIFLQFVDCVWQMTRQFPSAFEFNELFLITIL 530
++EW++ GH F R+G ++ +P+FL F+DCVWQ+ +QFP+ FEF+E FL+ +
Sbjct: 336 QREWVAAGHPFLTRLG----GTGASEEAPVFLLFLDCVWQLLQQFPADFEFSEFFLLALH 391
Query: 531 DHLYSCLFGTFLCNCEQQRFKE--------DVYTK-------------TISLWS----YI 565
D + TFL N +R K+ VYT +S+W Y
Sbjct: 392 DSVRVPDTLTFLRNTPWERGKQSGQLNSYTQVYTPGYSQPPAGNSFNLQLSVWDWDLRYS 451
Query: 566 NSQLDEFSNP 575
N+Q+ +F NP
Sbjct: 452 NAQILQFQNP 461
>gi|94721263 myotubularin related protein 12 [Homo sapiens]
Length = 747
Score = 135 bits (339), Expect = 2e-31
Identities = 107/390 (27%), Positives = 179/390 (45%), Gaps = 44/390 (11%)
Query: 174 IVCKDMRNLR--LAYKQEEQSKLGIFENLNKHAFPLSNGQALFAFSYKEKF-------PI 224
I CKD+R + L Y +EE+ K I + H + LF FSY P
Sbjct: 141 IHCKDLRVFQFCLRYTKEEEVKR-IVSGIIHHTQAPKLLKRLFLFSYATAAQNNTVTDPK 199
Query: 225 NGWKVYDPVSEY-----KRQGLPNESWKISKINSNYEFCDTYPAIIVVPTSVKDDDLSKV 279
N ++D + ++ + +G N +K +N Y+ C+ PA VVPT + ++++ +
Sbjct: 200 NHTVMFDTLKDWCWELERTKG--NMKYKAVSVNEGYKVCERLPAYFVVPTPLPEENVQR- 256
Query: 280 AAFRAKGRVPVLSWIHPESQATITRCSQPLVGPNDKRCKEDEKYLQTIMDANAQSHKLII 339
F+ G +P+ W A + + P +D + + +L I + I+
Sbjct: 257 --FQGHG-IPIWCWSCHNGSALLKMSALPKE-QDDGILQIQKSFLDGIYKTIHRPPYEIV 312
Query: 340 FDARQNSVADTNKTKGGGYESESAYPNAELVFLEIHNIHVMRESLRKLKEIVYPSIDEAR 399
D + E ++AY + +FL I N ++ + +
Sbjct: 313 ------KTEDLSSNFLSLQEIQTAYSKFKQLFL-IDNSTEFWDT-------------DIK 352
Query: 400 WLSNVDGTHWLEYIRMLLAGAVRIADKIESGKTSVVVHCSDGWDRTAQLTSLAMLMLDSY 459
W S ++ + WL+ IR L A+ I + +E+ +V++ + D ++SL LM+D +
Sbjct: 353 WFSLLESSSWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPH 412
Query: 460 YRTIKGFETLVEKEWISFGHRFALRVGHGNDNHADADRSPIFLQFVDCVWQMTRQFPSAF 519
RT GF++L++KEW+ GH F R H N D + P+FL F+DCVWQ+ Q P AF
Sbjct: 413 CRTRIGFQSLIQKEWVMGGHCFLDRCNHLRQN--DKEEVPVFLLFLDCVWQLVHQHPPAF 470
Query: 520 EFNELFLITILDHLYSCLFGTFLCNCEQQR 549
EF E +L + D LY +F TF N Q+
Sbjct: 471 EFTETYLTVLSDSLYIPIFSTFFFNSPHQK 500
>gi|153792780 additional sex combs like 2 [Homo sapiens]
Length = 1435
Score = 38.1 bits (87), Expect = 0.026
Identities = 22/48 (45%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
Query: 5 AAAAAAGCEGGGGPNPGPAGGRRPPRAAGGATAGSRQPSVETLDSPTG 52
AAAAAA GG P PGP GG+ P G TA P + + S TG
Sbjct: 678 AAAAAAASVGGTIPGPGPGGGQGPGEGGEGQTARGGSPGSDRV-SETG 724
>gi|117938274 jumpy isoform 3 [Homo sapiens]
Length = 538
Score = 37.4 bits (85), Expect = 0.045
Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 6/65 (9%)
Query: 432 TSVVVHCSDGWDRTAQLTSLAMLML---DSYYRTIKGFETL---VEKEWISFGHRFALRV 485
+ ++VHC GWDRT SL L L + ++K E L V +W FGH R+
Sbjct: 324 SGLLVHCISGWDRTPLFISLLRLSLWADGLIHTSLKPTEILYLTVAYDWFLFGHMLVDRL 383
Query: 486 GHGND 490
G +
Sbjct: 384 SKGEE 388
>gi|117938272 jumpy isoform 1 [Homo sapiens]
Length = 598
Score = 37.4 bits (85), Expect = 0.045
Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 6/65 (9%)
Query: 432 TSVVVHCSDGWDRTAQLTSLAMLML---DSYYRTIKGFETL---VEKEWISFGHRFALRV 485
+ ++VHC GWDRT SL L L + ++K E L V +W FGH R+
Sbjct: 324 SGLLVHCISGWDRTPLFISLLRLSLWADGLIHTSLKPTEILYLTVAYDWFLFGHMLVDRL 383
Query: 486 GHGND 490
G +
Sbjct: 384 SKGEE 388
>gi|117938270 jumpy isoform 2 [Homo sapiens]
Length = 650
Score = 37.4 bits (85), Expect = 0.045
Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 6/65 (9%)
Query: 432 TSVVVHCSDGWDRTAQLTSLAMLML---DSYYRTIKGFETL---VEKEWISFGHRFALRV 485
+ ++VHC GWDRT SL L L + ++K E L V +W FGH R+
Sbjct: 324 SGLLVHCISGWDRTPLFISLLRLSLWADGLIHTSLKPTEILYLTVAYDWFLFGHMLVDRL 383
Query: 486 GHGND 490
G +
Sbjct: 384 SKGEE 388
>gi|191250771 spire homolog 1 isoform b [Homo sapiens]
Length = 742
Score = 35.4 bits (80), Expect = 0.17
Identities = 20/36 (55%), Positives = 20/36 (55%), Gaps = 2/36 (5%)
Query: 7 AAAAGCEGGGGPNPGPAGGRRP--PRAAGGATAGSR 40
A AAG GGG P GG P P AAGGA GSR
Sbjct: 2 AQAAGPAGGGEPRTEAVGGEGPREPGAAGGAAGGSR 37
>gi|191250773 spire homolog 1 isoform a [Homo sapiens]
Length = 756
Score = 35.4 bits (80), Expect = 0.17
Identities = 20/36 (55%), Positives = 20/36 (55%), Gaps = 2/36 (5%)
Query: 7 AAAAGCEGGGGPNPGPAGGRRP--PRAAGGATAGSR 40
A AAG GGG P GG P P AAGGA GSR
Sbjct: 2 AQAAGPAGGGEPRTEAVGGEGPREPGAAGGAAGGSR 37
>gi|194294548 hsp70-interacting protein [Homo sapiens]
Length = 359
Score = 35.0 bits (79), Expect = 0.22
Identities = 21/71 (29%), Positives = 33/71 (46%), Gaps = 6/71 (8%)
Query: 4 PAAAAAAGCEGGGGPNPGPAGGRRPPRAAGG-----ATAGSRQPSVETLDSPTGSHVEWC 58
PA+ + GGGG + G +G RPPR G TAGS +P + + +W
Sbjct: 17 PASQGCSSGGGGGGSSAGGSGNSRPPRNLQGLLQMAITAGSEEPDPPP-EPMSEERRQWL 75
Query: 59 KQLIAATISSQ 69
++ ++A Q
Sbjct: 76 QEAMSAAFRGQ 86
>gi|112363070 hsp70-interacting protein [Homo sapiens]
Length = 359
Score = 35.0 bits (79), Expect = 0.22
Identities = 21/71 (29%), Positives = 33/71 (46%), Gaps = 6/71 (8%)
Query: 4 PAAAAAAGCEGGGGPNPGPAGGRRPPRAAGG-----ATAGSRQPSVETLDSPTGSHVEWC 58
PA+ + GGGG + G +G RPPR G TAGS +P + + +W
Sbjct: 17 PASQGCSSGGGGGGSSAGGSGNSRPPRNLQGLLQMAITAGSEEPDPPP-EPMSEERRQWL 75
Query: 59 KQLIAATISSQ 69
++ ++A Q
Sbjct: 76 QEAMSAAFRGQ 86
>gi|223633890 hypothetical protein LOC729956 [Homo sapiens]
Length = 538
Score = 34.7 bits (78), Expect = 0.29
Identities = 27/88 (30%), Positives = 34/88 (38%), Gaps = 9/88 (10%)
Query: 4 PAAAAAAGCEG-GGGPNPGPAGGRRPPRAAGGATAGSRQPSVETLDSPTGSHVEWCKQLI 62
P A A G G GGGP PG AG R G G + P GS +I
Sbjct: 142 PLAGGAGGAGGAGGGPGPGQAGWLEGGRTGGAGGRGG--------EGPGGSTAYVVCGVI 193
Query: 63 AATISSQISGSVTSENVSRDYKALRDGN 90
+ ++ + V SR +A RD N
Sbjct: 194 SFALAVGVGAKVAFSKASRAPRAHRDIN 221
>gi|169790811 SHC (Src homology 2 domain containing) transforming
protein 2 [Homo sapiens]
Length = 582
Score = 34.7 bits (78), Expect = 0.29
Identities = 19/39 (48%), Positives = 21/39 (53%), Gaps = 1/39 (2%)
Query: 4 PAAAAAAGCEGGGGPNPGPAGGRRPPRAAGGATAGSRQP 42
PAAA AAG GG P P PAG P A A G+ +P
Sbjct: 48 PAAARAAGASGGADPQPEPAGPGGVP-ALAAAVLGACEP 85
>gi|47578107 delangin isoform B [Homo sapiens]
Length = 2697
Score = 34.7 bits (78), Expect = 0.29
Identities = 21/73 (28%), Positives = 40/73 (54%), Gaps = 6/73 (8%)
Query: 29 PRAAGGATAGSRQPSVETLDSPTGSHVEWCKQLIAATISSQISGSVTSE-NVSRDYKALR 87
P+ AGGAT G+R S ET + GS + + +I +G V S+ ++++D +++
Sbjct: 511 PQEAGGATGGNRPASQETGSTGNGS-----RPALMVSIDLHQAGRVDSQASITQDSDSIK 565
Query: 88 DGNKLAQMEEAPL 100
++ Q +AP+
Sbjct: 566 KPEEIKQCNDAPV 578
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,023,049
Number of Sequences: 37866
Number of extensions: 1202884
Number of successful extensions: 7106
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 67
Number of HSP's that attempted gapping in prelim test: 6678
Number of HSP's gapped (non-prelim): 392
length of query: 665
length of database: 18,247,518
effective HSP length: 109
effective length of query: 556
effective length of database: 14,120,124
effective search space: 7850788944
effective search space used: 7850788944
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.