Guide to the Human Genome
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Search of human proteins with 28872751

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|28872751 dual oxidase 1 precursor [Homo sapiens]
         (1551 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|20149640 dual oxidase 1 precursor [Homo sapiens]                  3169   0.0  
gi|28872751 dual oxidase 1 precursor [Homo sapiens]                  3169   0.0  
gi|132566532 dual oxidase 2 precursor [Homo sapiens]                 2435   0.0  
gi|11136626 NADPH oxidase 3 [Homo sapiens]                            239   2e-62
gi|148536873 NADPH oxidase 1 isoform long [Homo sapiens]              237   7e-62
gi|20127624 NADPH oxidase, EF-hand calcium binding domain 5 [Hom...   231   5e-60
gi|6996021 cytochrome b-245 beta polypeptide [Homo sapiens]           220   7e-57
gi|7669510 NADPH oxidase 1 isoform long variant [Homo sapiens]        207   6e-53
gi|126517478 peroxidasin homolog-like [Homo sapiens]                  164   5e-40
gi|109150416 peroxidasin [Homo sapiens]                               155   4e-37
gi|219842348 NADPH oxidase 4 isoform c [Homo sapiens]                 149   2e-35
gi|8393843 NADPH oxidase 4 isoform a [Homo sapiens]                   149   2e-35
gi|4503595 eosinophil peroxidase [Homo sapiens]                       139   2e-32
gi|28558982 thyroid peroxidase isoform a [Homo sapiens]               130   8e-30
gi|28558988 thyroid peroxidase isoform d [Homo sapiens]               130   8e-30
gi|4557759 myeloperoxidase [Homo sapiens]                             124   7e-28
gi|231569458 lactoperoxidase isoform 3 preproprotein [Homo sapiens]   121   5e-27
gi|40549418 lactoperoxidase isoform 1 preproprotein [Homo sapiens]    121   5e-27
gi|28558984 thyroid peroxidase isoform b [Homo sapiens]               101   6e-21
gi|219842346 NADPH oxidase 4 isoform b [Homo sapiens]                  93   2e-18
gi|40254415 guanylate cyclase activator 1A (retina) [Homo sapiens]     70   2e-11
gi|28558990 thyroid peroxidase isoform e [Homo sapiens]                67   2e-10
gi|4506025 protein phosphatase 3, regulatory subunit B, alpha is...    62   4e-09
gi|98985795 neurocalcin delta [Homo sapiens]                           62   6e-09
gi|98985793 neurocalcin delta [Homo sapiens]                           62   6e-09
gi|98985791 neurocalcin delta [Homo sapiens]                           62   6e-09
gi|98985789 neurocalcin delta [Homo sapiens]                           62   6e-09
gi|98985787 neurocalcin delta [Homo sapiens]                           62   6e-09
gi|98985785 neurocalcin delta [Homo sapiens]                           62   6e-09
gi|98985783 neurocalcin delta [Homo sapiens]                           62   6e-09

>gi|20149640 dual oxidase 1 precursor [Homo sapiens]
          Length = 1551

 Score = 3169 bits (8216), Expect = 0.0
 Identities = 1551/1551 (100%), Positives = 1551/1551 (100%)

Query: 1    MGFCLALAWTLLVGAWTPLGAQNPISWEVQRFDGWYNNLMEHRWGSKGSRLQRLVPASYA 60
            MGFCLALAWTLLVGAWTPLGAQNPISWEVQRFDGWYNNLMEHRWGSKGSRLQRLVPASYA
Sbjct: 1    MGFCLALAWTLLVGAWTPLGAQNPISWEVQRFDGWYNNLMEHRWGSKGSRLQRLVPASYA 60

Query: 61   DGVYQPLGEPHLPNPRDLSNTISRGPAGLASLRNRTVLGVFFGYHVLSDLVSVETPGCPA 120
            DGVYQPLGEPHLPNPRDLSNTISRGPAGLASLRNRTVLGVFFGYHVLSDLVSVETPGCPA
Sbjct: 61   DGVYQPLGEPHLPNPRDLSNTISRGPAGLASLRNRTVLGVFFGYHVLSDLVSVETPGCPA 120

Query: 121  EFLNIRIPPGDPMFDPDQRGDVVLPFQRSRWDPETGRSPSNPRDPANQVTGWLDGSAIYG 180
            EFLNIRIPPGDPMFDPDQRGDVVLPFQRSRWDPETGRSPSNPRDPANQVTGWLDGSAIYG
Sbjct: 121  EFLNIRIPPGDPMFDPDQRGDVVLPFQRSRWDPETGRSPSNPRDPANQVTGWLDGSAIYG 180

Query: 181  SSHSWSDALRSFSRGQLASGPDPAFPRDSQNPLLMWAAPDPATGQNGPRGLYAFGAERGN 240
            SSHSWSDALRSFSRGQLASGPDPAFPRDSQNPLLMWAAPDPATGQNGPRGLYAFGAERGN
Sbjct: 181  SSHSWSDALRSFSRGQLASGPDPAFPRDSQNPLLMWAAPDPATGQNGPRGLYAFGAERGN 240

Query: 241  REPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAVYEWLPSFL 300
            REPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAVYEWLPSFL
Sbjct: 241  REPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAVYEWLPSFL 300

Query: 301  QKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVPPGVYMRNASCHFQGVINRNSSVSRA 360
            QKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVPPGVYMRNASCHFQGVINRNSSVSRA
Sbjct: 301  QKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVPPGVYMRNASCHFQGVINRNSSVSRA 360

Query: 361  LRVCNSYWSREHPSLQSAEDVDALLLGMASQIAEREDHVLVEDVRDFWPGPLKFSRTDHL 420
            LRVCNSYWSREHPSLQSAEDVDALLLGMASQIAEREDHVLVEDVRDFWPGPLKFSRTDHL
Sbjct: 361  LRVCNSYWSREHPSLQSAEDVDALLLGMASQIAEREDHVLVEDVRDFWPGPLKFSRTDHL 420

Query: 421  ASCLQRGRDLGLPSYTKARAALGLSPITRWQDINPALSRSNDTVLEATAALYNQDLSWLE 480
            ASCLQRGRDLGLPSYTKARAALGLSPITRWQDINPALSRSNDTVLEATAALYNQDLSWLE
Sbjct: 421  ASCLQRGRDLGLPSYTKARAALGLSPITRWQDINPALSRSNDTVLEATAALYNQDLSWLE 480

Query: 481  LLPGGLLESHRDPGPLFSTIVLEQFVRLRDGDRYWFENTRNGLFSKKEIEEIRNTTLQDV 540
            LLPGGLLESHRDPGPLFSTIVLEQFVRLRDGDRYWFENTRNGLFSKKEIEEIRNTTLQDV
Sbjct: 481  LLPGGLLESHRDPGPLFSTIVLEQFVRLRDGDRYWFENTRNGLFSKKEIEEIRNTTLQDV 540

Query: 541  LVAVINIDPSALQPNVFVWHKGDPCPQPRQLSTEGLPACAPSVVRDYFEGSGFGFGVTIG 600
            LVAVINIDPSALQPNVFVWHKGDPCPQPRQLSTEGLPACAPSVVRDYFEGSGFGFGVTIG
Sbjct: 541  LVAVINIDPSALQPNVFVWHKGDPCPQPRQLSTEGLPACAPSVVRDYFEGSGFGFGVTIG 600

Query: 601  TLCCFPLVSLLSAWIVARLRMRNFKRLQGQDRQSIVSEKLVGGMEALEWQGHKEPCRPVL 660
            TLCCFPLVSLLSAWIVARLRMRNFKRLQGQDRQSIVSEKLVGGMEALEWQGHKEPCRPVL
Sbjct: 601  TLCCFPLVSLLSAWIVARLRMRNFKRLQGQDRQSIVSEKLVGGMEALEWQGHKEPCRPVL 660

Query: 661  VYLQPGQIRVVDGRLTVLRTIQLQPPQKVNFVLSSNRGRRTLLLKIPKEYDLVLLFNLEE 720
            VYLQPGQIRVVDGRLTVLRTIQLQPPQKVNFVLSSNRGRRTLLLKIPKEYDLVLLFNLEE
Sbjct: 661  VYLQPGQIRVVDGRLTVLRTIQLQPPQKVNFVLSSNRGRRTLLLKIPKEYDLVLLFNLEE 720

Query: 721  ERQALVENLRGALKESGLSIQEWELREQELMRAAVTREQRRHLLETFFRHLFSQVLDINQ 780
            ERQALVENLRGALKESGLSIQEWELREQELMRAAVTREQRRHLLETFFRHLFSQVLDINQ
Sbjct: 721  ERQALVENLRGALKESGLSIQEWELREQELMRAAVTREQRRHLLETFFRHLFSQVLDINQ 780

Query: 781  ADAGTLPLDSSQKVREALTCELSRAEFAESLGLKPQDMFVESMFSLADKDGNGYLSFREF 840
            ADAGTLPLDSSQKVREALTCELSRAEFAESLGLKPQDMFVESMFSLADKDGNGYLSFREF
Sbjct: 781  ADAGTLPLDSSQKVREALTCELSRAEFAESLGLKPQDMFVESMFSLADKDGNGYLSFREF 840

Query: 841  LDILVVFMKGSPEEKSRLMFRMYDFDGNGLISKDEFIRMLRSFIEISNNCLSKAQLAEVV 900
            LDILVVFMKGSPEEKSRLMFRMYDFDGNGLISKDEFIRMLRSFIEISNNCLSKAQLAEVV
Sbjct: 841  LDILVVFMKGSPEEKSRLMFRMYDFDGNGLISKDEFIRMLRSFIEISNNCLSKAQLAEVV 900

Query: 901  ESMFRESGFQDKEELTWEDFHFMLRDHNSELRFTQLCVKGVEVPEVIKDLCRRASYISQD 960
            ESMFRESGFQDKEELTWEDFHFMLRDHNSELRFTQLCVKGVEVPEVIKDLCRRASYISQD
Sbjct: 901  ESMFRESGFQDKEELTWEDFHFMLRDHNSELRFTQLCVKGVEVPEVIKDLCRRASYISQD 960

Query: 961  MICPSPRVSARCSRSDIETELTPQRLQCPMDTDPPQEIRRRFGKKVTSFQPLLFTEAHRE 1020
            MICPSPRVSARCSRSDIETELTPQRLQCPMDTDPPQEIRRRFGKKVTSFQPLLFTEAHRE
Sbjct: 961  MICPSPRVSARCSRSDIETELTPQRLQCPMDTDPPQEIRRRFGKKVTSFQPLLFTEAHRE 1020

Query: 1021 KFQRSCLHQTVQQFKRFIENYRRHIGCVAVFYAIAGGLFLERAYYYAFAAHHTGITDTTR 1080
            KFQRSCLHQTVQQFKRFIENYRRHIGCVAVFYAIAGGLFLERAYYYAFAAHHTGITDTTR
Sbjct: 1021 KFQRSCLHQTVQQFKRFIENYRRHIGCVAVFYAIAGGLFLERAYYYAFAAHHTGITDTTR 1080

Query: 1081 VGIILSRGTAASISFMFSYILLTMCRNLITFLRETFLNRYVPFDAAVDFHRLIASTAIVL 1140
            VGIILSRGTAASISFMFSYILLTMCRNLITFLRETFLNRYVPFDAAVDFHRLIASTAIVL
Sbjct: 1081 VGIILSRGTAASISFMFSYILLTMCRNLITFLRETFLNRYVPFDAAVDFHRLIASTAIVL 1140

Query: 1141 TVLHSVGHVVNVYLFSISPLSVLSCLFPGLFHDDGSELPQKYYWWFFQTVPGLTGVVLLL 1200
            TVLHSVGHVVNVYLFSISPLSVLSCLFPGLFHDDGSELPQKYYWWFFQTVPGLTGVVLLL
Sbjct: 1141 TVLHSVGHVVNVYLFSISPLSVLSCLFPGLFHDDGSELPQKYYWWFFQTVPGLTGVVLLL 1200

Query: 1201 ILAIMYVFASHHFRRRSFRGFWLTHHLYILLYVLLIIHGSFALIQLPRFHIFFLVPAIIY 1260
            ILAIMYVFASHHFRRRSFRGFWLTHHLYILLYVLLIIHGSFALIQLPRFHIFFLVPAIIY
Sbjct: 1201 ILAIMYVFASHHFRRRSFRGFWLTHHLYILLYVLLIIHGSFALIQLPRFHIFFLVPAIIY 1260

Query: 1261 GGDKLVSLSRKKVEISVVKAELLPSGVTHLRFQRPQGFEYKSGQWVRIACLALGTTEYHP 1320
            GGDKLVSLSRKKVEISVVKAELLPSGVTHLRFQRPQGFEYKSGQWVRIACLALGTTEYHP
Sbjct: 1261 GGDKLVSLSRKKVEISVVKAELLPSGVTHLRFQRPQGFEYKSGQWVRIACLALGTTEYHP 1320

Query: 1321 FTLTSAPHEDTLSLHIRAAGPWTTRLREIYSAPTGDRCARYPKLYLDGPFGEGHQEWHKF 1380
            FTLTSAPHEDTLSLHIRAAGPWTTRLREIYSAPTGDRCARYPKLYLDGPFGEGHQEWHKF
Sbjct: 1321 FTLTSAPHEDTLSLHIRAAGPWTTRLREIYSAPTGDRCARYPKLYLDGPFGEGHQEWHKF 1380

Query: 1381 EVSVLVGGGIGVTPFASILKDLVFKSSVSCQVFCKKIYFIWVTRTQRQFEWLADIIREVE 1440
            EVSVLVGGGIGVTPFASILKDLVFKSSVSCQVFCKKIYFIWVTRTQRQFEWLADIIREVE
Sbjct: 1381 EVSVLVGGGIGVTPFASILKDLVFKSSVSCQVFCKKIYFIWVTRTQRQFEWLADIIREVE 1440

Query: 1441 ENDHQDLVSVHIYITQLAEKFDLRTTMLYICERHFQKVLNRSLFTGLRSITHFGRPPFEP 1500
            ENDHQDLVSVHIYITQLAEKFDLRTTMLYICERHFQKVLNRSLFTGLRSITHFGRPPFEP
Sbjct: 1441 ENDHQDLVSVHIYITQLAEKFDLRTTMLYICERHFQKVLNRSLFTGLRSITHFGRPPFEP 1500

Query: 1501 FFNSLQEVHPQVRKIGVFSCGPPGMTKNVEKACQLINRQDRTHFSHHYENF 1551
            FFNSLQEVHPQVRKIGVFSCGPPGMTKNVEKACQLINRQDRTHFSHHYENF
Sbjct: 1501 FFNSLQEVHPQVRKIGVFSCGPPGMTKNVEKACQLINRQDRTHFSHHYENF 1551


>gi|28872751 dual oxidase 1 precursor [Homo sapiens]
          Length = 1551

 Score = 3169 bits (8216), Expect = 0.0
 Identities = 1551/1551 (100%), Positives = 1551/1551 (100%)

Query: 1    MGFCLALAWTLLVGAWTPLGAQNPISWEVQRFDGWYNNLMEHRWGSKGSRLQRLVPASYA 60
            MGFCLALAWTLLVGAWTPLGAQNPISWEVQRFDGWYNNLMEHRWGSKGSRLQRLVPASYA
Sbjct: 1    MGFCLALAWTLLVGAWTPLGAQNPISWEVQRFDGWYNNLMEHRWGSKGSRLQRLVPASYA 60

Query: 61   DGVYQPLGEPHLPNPRDLSNTISRGPAGLASLRNRTVLGVFFGYHVLSDLVSVETPGCPA 120
            DGVYQPLGEPHLPNPRDLSNTISRGPAGLASLRNRTVLGVFFGYHVLSDLVSVETPGCPA
Sbjct: 61   DGVYQPLGEPHLPNPRDLSNTISRGPAGLASLRNRTVLGVFFGYHVLSDLVSVETPGCPA 120

Query: 121  EFLNIRIPPGDPMFDPDQRGDVVLPFQRSRWDPETGRSPSNPRDPANQVTGWLDGSAIYG 180
            EFLNIRIPPGDPMFDPDQRGDVVLPFQRSRWDPETGRSPSNPRDPANQVTGWLDGSAIYG
Sbjct: 121  EFLNIRIPPGDPMFDPDQRGDVVLPFQRSRWDPETGRSPSNPRDPANQVTGWLDGSAIYG 180

Query: 181  SSHSWSDALRSFSRGQLASGPDPAFPRDSQNPLLMWAAPDPATGQNGPRGLYAFGAERGN 240
            SSHSWSDALRSFSRGQLASGPDPAFPRDSQNPLLMWAAPDPATGQNGPRGLYAFGAERGN
Sbjct: 181  SSHSWSDALRSFSRGQLASGPDPAFPRDSQNPLLMWAAPDPATGQNGPRGLYAFGAERGN 240

Query: 241  REPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAVYEWLPSFL 300
            REPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAVYEWLPSFL
Sbjct: 241  REPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAVYEWLPSFL 300

Query: 301  QKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVPPGVYMRNASCHFQGVINRNSSVSRA 360
            QKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVPPGVYMRNASCHFQGVINRNSSVSRA
Sbjct: 301  QKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVPPGVYMRNASCHFQGVINRNSSVSRA 360

Query: 361  LRVCNSYWSREHPSLQSAEDVDALLLGMASQIAEREDHVLVEDVRDFWPGPLKFSRTDHL 420
            LRVCNSYWSREHPSLQSAEDVDALLLGMASQIAEREDHVLVEDVRDFWPGPLKFSRTDHL
Sbjct: 361  LRVCNSYWSREHPSLQSAEDVDALLLGMASQIAEREDHVLVEDVRDFWPGPLKFSRTDHL 420

Query: 421  ASCLQRGRDLGLPSYTKARAALGLSPITRWQDINPALSRSNDTVLEATAALYNQDLSWLE 480
            ASCLQRGRDLGLPSYTKARAALGLSPITRWQDINPALSRSNDTVLEATAALYNQDLSWLE
Sbjct: 421  ASCLQRGRDLGLPSYTKARAALGLSPITRWQDINPALSRSNDTVLEATAALYNQDLSWLE 480

Query: 481  LLPGGLLESHRDPGPLFSTIVLEQFVRLRDGDRYWFENTRNGLFSKKEIEEIRNTTLQDV 540
            LLPGGLLESHRDPGPLFSTIVLEQFVRLRDGDRYWFENTRNGLFSKKEIEEIRNTTLQDV
Sbjct: 481  LLPGGLLESHRDPGPLFSTIVLEQFVRLRDGDRYWFENTRNGLFSKKEIEEIRNTTLQDV 540

Query: 541  LVAVINIDPSALQPNVFVWHKGDPCPQPRQLSTEGLPACAPSVVRDYFEGSGFGFGVTIG 600
            LVAVINIDPSALQPNVFVWHKGDPCPQPRQLSTEGLPACAPSVVRDYFEGSGFGFGVTIG
Sbjct: 541  LVAVINIDPSALQPNVFVWHKGDPCPQPRQLSTEGLPACAPSVVRDYFEGSGFGFGVTIG 600

Query: 601  TLCCFPLVSLLSAWIVARLRMRNFKRLQGQDRQSIVSEKLVGGMEALEWQGHKEPCRPVL 660
            TLCCFPLVSLLSAWIVARLRMRNFKRLQGQDRQSIVSEKLVGGMEALEWQGHKEPCRPVL
Sbjct: 601  TLCCFPLVSLLSAWIVARLRMRNFKRLQGQDRQSIVSEKLVGGMEALEWQGHKEPCRPVL 660

Query: 661  VYLQPGQIRVVDGRLTVLRTIQLQPPQKVNFVLSSNRGRRTLLLKIPKEYDLVLLFNLEE 720
            VYLQPGQIRVVDGRLTVLRTIQLQPPQKVNFVLSSNRGRRTLLLKIPKEYDLVLLFNLEE
Sbjct: 661  VYLQPGQIRVVDGRLTVLRTIQLQPPQKVNFVLSSNRGRRTLLLKIPKEYDLVLLFNLEE 720

Query: 721  ERQALVENLRGALKESGLSIQEWELREQELMRAAVTREQRRHLLETFFRHLFSQVLDINQ 780
            ERQALVENLRGALKESGLSIQEWELREQELMRAAVTREQRRHLLETFFRHLFSQVLDINQ
Sbjct: 721  ERQALVENLRGALKESGLSIQEWELREQELMRAAVTREQRRHLLETFFRHLFSQVLDINQ 780

Query: 781  ADAGTLPLDSSQKVREALTCELSRAEFAESLGLKPQDMFVESMFSLADKDGNGYLSFREF 840
            ADAGTLPLDSSQKVREALTCELSRAEFAESLGLKPQDMFVESMFSLADKDGNGYLSFREF
Sbjct: 781  ADAGTLPLDSSQKVREALTCELSRAEFAESLGLKPQDMFVESMFSLADKDGNGYLSFREF 840

Query: 841  LDILVVFMKGSPEEKSRLMFRMYDFDGNGLISKDEFIRMLRSFIEISNNCLSKAQLAEVV 900
            LDILVVFMKGSPEEKSRLMFRMYDFDGNGLISKDEFIRMLRSFIEISNNCLSKAQLAEVV
Sbjct: 841  LDILVVFMKGSPEEKSRLMFRMYDFDGNGLISKDEFIRMLRSFIEISNNCLSKAQLAEVV 900

Query: 901  ESMFRESGFQDKEELTWEDFHFMLRDHNSELRFTQLCVKGVEVPEVIKDLCRRASYISQD 960
            ESMFRESGFQDKEELTWEDFHFMLRDHNSELRFTQLCVKGVEVPEVIKDLCRRASYISQD
Sbjct: 901  ESMFRESGFQDKEELTWEDFHFMLRDHNSELRFTQLCVKGVEVPEVIKDLCRRASYISQD 960

Query: 961  MICPSPRVSARCSRSDIETELTPQRLQCPMDTDPPQEIRRRFGKKVTSFQPLLFTEAHRE 1020
            MICPSPRVSARCSRSDIETELTPQRLQCPMDTDPPQEIRRRFGKKVTSFQPLLFTEAHRE
Sbjct: 961  MICPSPRVSARCSRSDIETELTPQRLQCPMDTDPPQEIRRRFGKKVTSFQPLLFTEAHRE 1020

Query: 1021 KFQRSCLHQTVQQFKRFIENYRRHIGCVAVFYAIAGGLFLERAYYYAFAAHHTGITDTTR 1080
            KFQRSCLHQTVQQFKRFIENYRRHIGCVAVFYAIAGGLFLERAYYYAFAAHHTGITDTTR
Sbjct: 1021 KFQRSCLHQTVQQFKRFIENYRRHIGCVAVFYAIAGGLFLERAYYYAFAAHHTGITDTTR 1080

Query: 1081 VGIILSRGTAASISFMFSYILLTMCRNLITFLRETFLNRYVPFDAAVDFHRLIASTAIVL 1140
            VGIILSRGTAASISFMFSYILLTMCRNLITFLRETFLNRYVPFDAAVDFHRLIASTAIVL
Sbjct: 1081 VGIILSRGTAASISFMFSYILLTMCRNLITFLRETFLNRYVPFDAAVDFHRLIASTAIVL 1140

Query: 1141 TVLHSVGHVVNVYLFSISPLSVLSCLFPGLFHDDGSELPQKYYWWFFQTVPGLTGVVLLL 1200
            TVLHSVGHVVNVYLFSISPLSVLSCLFPGLFHDDGSELPQKYYWWFFQTVPGLTGVVLLL
Sbjct: 1141 TVLHSVGHVVNVYLFSISPLSVLSCLFPGLFHDDGSELPQKYYWWFFQTVPGLTGVVLLL 1200

Query: 1201 ILAIMYVFASHHFRRRSFRGFWLTHHLYILLYVLLIIHGSFALIQLPRFHIFFLVPAIIY 1260
            ILAIMYVFASHHFRRRSFRGFWLTHHLYILLYVLLIIHGSFALIQLPRFHIFFLVPAIIY
Sbjct: 1201 ILAIMYVFASHHFRRRSFRGFWLTHHLYILLYVLLIIHGSFALIQLPRFHIFFLVPAIIY 1260

Query: 1261 GGDKLVSLSRKKVEISVVKAELLPSGVTHLRFQRPQGFEYKSGQWVRIACLALGTTEYHP 1320
            GGDKLVSLSRKKVEISVVKAELLPSGVTHLRFQRPQGFEYKSGQWVRIACLALGTTEYHP
Sbjct: 1261 GGDKLVSLSRKKVEISVVKAELLPSGVTHLRFQRPQGFEYKSGQWVRIACLALGTTEYHP 1320

Query: 1321 FTLTSAPHEDTLSLHIRAAGPWTTRLREIYSAPTGDRCARYPKLYLDGPFGEGHQEWHKF 1380
            FTLTSAPHEDTLSLHIRAAGPWTTRLREIYSAPTGDRCARYPKLYLDGPFGEGHQEWHKF
Sbjct: 1321 FTLTSAPHEDTLSLHIRAAGPWTTRLREIYSAPTGDRCARYPKLYLDGPFGEGHQEWHKF 1380

Query: 1381 EVSVLVGGGIGVTPFASILKDLVFKSSVSCQVFCKKIYFIWVTRTQRQFEWLADIIREVE 1440
            EVSVLVGGGIGVTPFASILKDLVFKSSVSCQVFCKKIYFIWVTRTQRQFEWLADIIREVE
Sbjct: 1381 EVSVLVGGGIGVTPFASILKDLVFKSSVSCQVFCKKIYFIWVTRTQRQFEWLADIIREVE 1440

Query: 1441 ENDHQDLVSVHIYITQLAEKFDLRTTMLYICERHFQKVLNRSLFTGLRSITHFGRPPFEP 1500
            ENDHQDLVSVHIYITQLAEKFDLRTTMLYICERHFQKVLNRSLFTGLRSITHFGRPPFEP
Sbjct: 1441 ENDHQDLVSVHIYITQLAEKFDLRTTMLYICERHFQKVLNRSLFTGLRSITHFGRPPFEP 1500

Query: 1501 FFNSLQEVHPQVRKIGVFSCGPPGMTKNVEKACQLINRQDRTHFSHHYENF 1551
            FFNSLQEVHPQVRKIGVFSCGPPGMTKNVEKACQLINRQDRTHFSHHYENF
Sbjct: 1501 FFNSLQEVHPQVRKIGVFSCGPPGMTKNVEKACQLINRQDRTHFSHHYENF 1551


>gi|132566532 dual oxidase 2 precursor [Homo sapiens]
          Length = 1548

 Score = 2435 bits (6310), Expect = 0.0
 Identities = 1207/1551 (77%), Positives = 1331/1551 (85%), Gaps = 15/1551 (0%)

Query: 5    LALAWTLLVGAWTPLGAQNPIS--WEVQRFDGWYNNLMEHRWGSKGSRLQRLVPASYADG 62
            L L   LL G+  P G Q+ +S  WEVQR+DGW+NNL  H  G+ G RLQR VPA+YADG
Sbjct: 9    LMLLGALLTGSLGPSGNQDALSLPWEVQRYDGWFNNLRHHERGAVGCRLQRRVPANYADG 68

Query: 63   VYQPLGEPHLPNPRDLSNTISRGPAGLASLRNRTVLGVFFGYHVLSDLVSVETPGCPAEF 122
            VYQ L EP LPNPR LSN  +RG AGL SL NRTVLGVFFGYHVLSD+VSVETPGCPAEF
Sbjct: 69   VYQALEEPQLPNPRRLSNAATRGIAGLPSLHNRTVLGVFFGYHVLSDVVSVETPGCPAEF 128

Query: 123  LNIRIPPGDPMFDPDQRGDVVLPFQRSRWDPETGRSPSNPRDPANQVTGWLDGSAIYGSS 182
            LNIRIPPGDP+FDPDQRGDVVLPFQRSRWDPETGRSPSNPRD ANQVTGWLDGSAIYGSS
Sbjct: 129  LNIRIPPGDPVFDPDQRGDVVLPFQRSRWDPETGRSPSNPRDLANQVTGWLDGSAIYGSS 188

Query: 183  HSWSDALRSFSRGQLASGPDPAFPRDSQNPLLMWAAPDPATGQNGPRGLYAFGAERGNRE 242
            HSWSDALRSFS GQLASGPDPAFPRDSQNPLLMWAAPDPATGQNGPRGLYAFGAERGNRE
Sbjct: 189  HSWSDALRSFSGGQLASGPDPAFPRDSQNPLLMWAAPDPATGQNGPRGLYAFGAERGNRE 248

Query: 243  PFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAVYEWLPSFLQK 302
            PFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAVYEWLPSFLQK
Sbjct: 249  PFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAVYEWLPSFLQK 308

Query: 303  TLPEYTGYRPFLDPSISSEFVAASEQFLSTMVPPGVYMRNASCHFQGVINRNSSVSRALR 362
            TLPEYTGYRPFLDPSIS EFV ASEQF STMVPPGVYMRNASCHF+ V+N+    S+ALR
Sbjct: 309  TLPEYTGYRPFLDPSISPEFVVASEQFFSTMVPPGVYMRNASCHFRKVLNKGFQSSQALR 368

Query: 363  VCNSYWSREHPSLQSAEDVDALLLGMASQIAEREDHVLVEDVRDFWPGPLKFSRTDHLAS 422
            VCN+YW RE+P+L S ++V+ LLLGMASQI+E ED+++VED+RD+WPGP KFSRTD++AS
Sbjct: 369  VCNNYWIRENPNLNSTQEVNELLLGMASQISELEDNIVVEDLRDYWPGPGKFSRTDYVAS 428

Query: 423  CLQRGRDLGLPSYTKARAALGLSPITRWQDINPALSRSNDTVLEATAALYNQDLSWLELL 482
             +QRGRD+GLPSY++A  A GL     W D+NP +   +  VLEATAALYNQDLS LELL
Sbjct: 429  SIQRGRDMGLPSYSQALLAFGLDIPRNWSDLNPNV---DPQVLEATAALYNQDLSQLELL 485

Query: 483  PGGLLESHRDPGPLFSTIVLEQFVRLRDGDRYWFENTRNGLFSKKEIEEIRNTTLQDVLV 542
             GGLLESH DPGPLFS IVL+QFVRLRDGDRYWFENTRNGLFSKKEIE+IRNTTL+DVLV
Sbjct: 486  LGGLLESHGDPGPLFSAIVLDQFVRLRDGDRYWFENTRNGLFSKKEIEDIRNTTLRDVLV 545

Query: 543  AVINIDPSALQPNVFVWHKGDPCPQPRQLSTEGLPACAPSVVRDYFEGSGFGFGVTIGTL 602
            AVINIDPSALQPNVFVWHKG PCPQP+QL+T+GLP CAP  V D+FEGS  GF +TI  L
Sbjct: 546  AVINIDPSALQPNVFVWHKGAPCPQPKQLTTDGLPQCAPLTVLDFFEGSSPGFAITIIAL 605

Query: 603  CCFPLVSLLSAWIVARLRMRNFKRLQGQDRQSIVSEKLVGGMEALEWQGHKEPCRPVLVY 662
            CC PLVSLL + +VA  R R  K+LQ + ++S+  E    G+ A+EW G KE   P+++ 
Sbjct: 606  CCLPLVSLLLSGVVAYFRGREHKKLQKKLKESVKKEAAKDGVPAMEWPGPKERSSPIIIQ 665

Query: 663  LQPGQ-IRVVDGRLTVLRTIQLQPPQKVNFVLSSNRGRRTLLLKIPKEYDLVLLFNLEEE 721
            L   + ++V++  LTVLR +QLQP Q+VN +LS+NRG RTLLLKIPKEYDLVLLF+ EEE
Sbjct: 666  LLSDRCLQVLNRHLTVLRVVQLQPLQQVNLILSNNRGCRTLLLKIPKEYDLVLLFSSEEE 725

Query: 722  RQALVENLRGALKESGLSIQEWELREQELMRAAVTREQRRHLLETFFRHLFSQVLDINQA 781
            R A V+ L        L +   E+ E+EL R AVT++QR  +LE FFRHLF+QVLDINQA
Sbjct: 726  RGAFVQQLWDFCVRWALGLHVAEMSEKELFRKAVTKQQRERILEIFFRHLFAQVLDINQA 785

Query: 782  DAGTLPLDSSQKVREALTCELSRAEFAESLGLKPQDMFVESMFSLADKDGNGYLSFREFL 841
            DAGTLPLDSSQKVREALTCELSRAEFAESLGLKPQDMFVESMFSLADKDGNGYLSFREFL
Sbjct: 786  DAGTLPLDSSQKVREALTCELSRAEFAESLGLKPQDMFVESMFSLADKDGNGYLSFREFL 845

Query: 842  DILVVFMKGSPEEKSRLMFRMYDFDGNGLISKDEFIRMLRSFIEISNNCLSKAQLAEVVE 901
            DILVVFMKGSPE+KSRLMF MYD D NG +SKDEF  M+RSFIEISNNCLSKAQLAEVVE
Sbjct: 846  DILVVFMKGSPEDKSRLMFTMYDLDENGFLSKDEFFTMMRSFIEISNNCLSKAQLAEVVE 905

Query: 902  SMFRESGFQDKEELTWEDFHFMLRDHNSELRFTQLCVKGVEVP-EVIKDLCRRASYISQD 960
            SMFRESGFQDKEELTWEDFHFMLRDH+SELRFTQLCVKG       I+D+ +      Q+
Sbjct: 906  SMFRESGFQDKEELTWEDFHFMLRDHDSELRFTQLCVKGGGGGGNGIRDIFK------QN 959

Query: 961  MICPSPRVSARCSRSDIETELTPQRLQCPMDTDPPQEIRRRFGKKVTSFQPLLFTEAHRE 1020
            + C    ++           L P   + P    P   +++RFGKK     P L+TEA +E
Sbjct: 960  ISCRVSFITRTPGERSHPQGLGPPAPEAPELGGPG--LKKRFGKKAAVPTPRLYTEALQE 1017

Query: 1021 KFQRSCLHQTVQQFKRFIENYRRHIGCVAVFYAIAGGLFLERAYYYAFAAHHTGITDTTR 1080
            K QR  L Q +QQ+KRF+ENYRRHI CVA+F AI  G+F +RAYYY FA+  + I  TT 
Sbjct: 1018 KMQRGFLAQKLQQYKRFVENYRRHIVCVAIFSAICVGVFADRAYYYGFASPPSDIAQTTL 1077

Query: 1081 VGIILSRGTAASISFMFSYILLTMCRNLITFLRETFLNRYVPFDAAVDFHRLIASTAIVL 1140
            VGIILSRGTAAS+SFMFSYILLTMCRNLITFLRETFLNRYVPFDAAVDFHR IA  A+VL
Sbjct: 1078 VGIILSRGTAASVSFMFSYILLTMCRNLITFLRETFLNRYVPFDAAVDFHRWIAMAAVVL 1137

Query: 1141 TVLHSVGHVVNVYLFSISPLSVLSCLFPGLFHDDGSELPQKYYWWFFQTVPGLTGVVLLL 1200
             +LHS GH VNVY+FS+SPLS+L+C+FP +F +DGS+LPQK+YWWFFQTVPG+TGV+LLL
Sbjct: 1138 AILHSAGHAVNVYIFSVSPLSLLACIFPNVFVNDGSKLPQKFYWWFFQTVPGMTGVLLLL 1197

Query: 1201 ILAIMYVFASHHFRRRSFRGFWLTHHLYILLYVLLIIHGSFALIQLPRFHIFFLVPAIIY 1260
            +LAIMYVFASHHFRRRSFRGFWLTHHLYILLY LLIIHGS+ALIQLP FHI+FLVPAIIY
Sbjct: 1198 VLAIMYVFASHHFRRRSFRGFWLTHHLYILLYALLIIHGSYALIQLPTFHIYFLVPAIIY 1257

Query: 1261 GGDKLVSLSRKKVEISVVKAELLPSGVTHLRFQRPQGFEYKSGQWVRIACLALGTTEYHP 1320
            GGDKLVSLSRKKVEISVVKAELLPSGVT+L+FQRPQGFEYKSGQWVRIACLALGTTEYHP
Sbjct: 1258 GGDKLVSLSRKKVEISVVKAELLPSGVTYLQFQRPQGFEYKSGQWVRIACLALGTTEYHP 1317

Query: 1321 FTLTSAPHEDTLSLHIRAAGPWTTRLREIYSAPTGDRCARYPKLYLDGPFGEGHQEWHKF 1380
            FTLTSAPHEDTLSLHIRA GPWTTRLREIYS+P G+ CA YPKLYLDGPFGEGHQEWHKF
Sbjct: 1318 FTLTSAPHEDTLSLHIRAVGPWTTRLREIYSSPKGNGCAGYPKLYLDGPFGEGHQEWHKF 1377

Query: 1381 EVSVLVGGGIGVTPFASILKDLVFKSSVSCQVFCKKIYFIWVTRTQRQFEWLADIIREVE 1440
            EVSVLVGGGIGVTPFASILKDLVFKSS+  Q+ CKKIYFIWVTRTQRQFEWLADII+EVE
Sbjct: 1378 EVSVLVGGGIGVTPFASILKDLVFKSSLGSQMLCKKIYFIWVTRTQRQFEWLADIIQEVE 1437

Query: 1441 ENDHQDLVSVHIYITQLAEKFDLRTTMLYICERHFQKVLNRSLFTGLRSITHFGRPPFEP 1500
            ENDHQDLVSVHIY+TQLAEKFDLRTTMLYICERHFQKVLNRSLFTGLRSITHFGRPPFEP
Sbjct: 1438 ENDHQDLVSVHIYVTQLAEKFDLRTTMLYICERHFQKVLNRSLFTGLRSITHFGRPPFEP 1497

Query: 1501 FFNSLQEVHPQVRKIGVFSCGPPGMTKNVEKACQLINRQDRTHFSHHYENF 1551
            FFNSLQEVHPQVRKIGVFSCGPPGMTKNVEKACQL+NRQDR HF HHYENF
Sbjct: 1498 FFNSLQEVHPQVRKIGVFSCGPPGMTKNVEKACQLVNRQDRAHFMHHYENF 1548


>gi|11136626 NADPH oxidase 3 [Homo sapiens]
          Length = 568

 Score =  239 bits (609), Expect = 2e-62
 Identities = 164/556 (29%), Positives = 268/556 (48%), Gaps = 75/556 (13%)

Query: 1058 LFLERAYYYAF--AAHHTGITDTTRVGIILSRGTAASISFMFSYILLTMCRNLITFLRET 1115
            LF++  Y+Y    + H+T +   + +    +R +A  ++F    IL+ + RNLI+F+R T
Sbjct: 26   LFIDTFYWYEEEESFHYTRVILGSTLA--WARASALCLNFNCMLILIPVSRNLISFIRGT 83

Query: 1116 FLNRYVPFDAAVD----FHRLIASTAIVLTVLHSVGHVVNVYLFSISPLSVLSCLFPGL- 1170
             +    P+   +D    FH+L+A    V   +H V H  N+  +  S       L   L 
Sbjct: 84   SICCRGPWRRQLDKNLRFHKLVAYGIAVNATIHIVAHFFNLERYHWSQSEEAQGLLAALS 143

Query: 1171 ---------FHDDGSELPQKYYWWFFQTVPGLTGVVLLLILAIMYVFASHHFRRRSFRGF 1221
                     + +     P        +T+ G+TG+V+ L L ++   ++   R+ S+  F
Sbjct: 144  KLGNTPNESYLNPVRTFPTNTTTELLRTIAGVTGLVISLALVLIMTSSTEFIRQASYELF 203

Query: 1222 WLTHHLYILLYVLLIIHGSFALIQ-----------------------------LPRFH-- 1250
            W THH++I+ ++ L IHG+  +++                             +P+F   
Sbjct: 204  WYTHHVFIVFFLSLAIHGTGRIVRGQTQDSLSLHNITFCRDRYAEWQTVAQCPVPQFSGK 263

Query: 1251 -----IFFLVPAIIYGGDKLVSLSRKKVEISVVKAELLPSGVTHLRFQRPQGFEYKSGQW 1305
                  + L P ++Y  ++++   R + E+ + K    PSGV  L  ++ +GF+   GQ+
Sbjct: 264  EPSAWKWILGPVVLYACERIIRFWRFQQEVVITKVVSHPSGVLELHMKK-RGFKMAPGQY 322

Query: 1306 VRIACLALGTTEYHPFTLTSAPHEDTLSLHIRAAGPWTTRLREIYSAPTGDRCAR---YP 1362
            + + C A+ + E+HPFTLTSAP ED  S+HIRAAG WT  L E + A  G         P
Sbjct: 323  ILVQCPAISSLEWHPFTLTSAPQEDFFSVHIRAAGDWTAALLEAFGA-EGQALQEPWSLP 381

Query: 1363 KLYLDGPFGEGHQEWHKFEVSVLVGGGIGVTPFASILKDLVFK-SSVSCQVFCKKIYFIW 1421
            +L +DGPFG    +   + V V V  GIGVTPFA++LK + +K S     +   K+YF W
Sbjct: 382  RLAVDGPFGTALTDVFHYPVCVCVAAGIGVTPFAALLKSIWYKCSEAQTPLKLSKVYFYW 441

Query: 1422 VTRTQRQFEWLADIIREVE----ENDHQDLVSVHIYITQLAEKFDLRTTMLYICERHFQK 1477
            + R  R FEW AD++  +E    E      +S HI++T   E   L   +      H+ +
Sbjct: 442  ICRDARAFEWFADLLLSLETRMSEQGKTHFLSYHIFLTGWDENQALHIAL------HWDE 495

Query: 1478 VLNRSLFTGLRSITHFGRPPFEPFFNSLQEVHPQVRKIGVFSCGPPGMTKNVEKACQLIN 1537
              N  + TGL+  T +GRP +   F  +   HP    IGVF CGP  +++ ++K C L +
Sbjct: 496  --NTDVITGLKQKTFYGRPNWNNEFKQIAYNHPS-SSIGVFFCGPKALSRTLQKMCHLYS 552

Query: 1538 RQD--RTHFSHHYENF 1551
              D    HF ++ E+F
Sbjct: 553  SADPRGVHFYYNKESF 568


>gi|148536873 NADPH oxidase 1 isoform long [Homo sapiens]
          Length = 564

 Score =  237 bits (604), Expect = 7e-62
 Identities = 170/562 (30%), Positives = 275/562 (48%), Gaps = 80/562 (14%)

Query: 1050 VFYAIAGGLFLERAYYYAFAAHHTGITDTTRVGIILSRGTAASISFMFSYILLTMCRNLI 1109
            VF  +   L  E+A  Y +     G T      +  +R +A  ++F  + ILL +CRNL+
Sbjct: 23   VFLFVDAFLKYEKADKYYYTRKILGST------LACARASALCLNFNSTLILLPVCRNLL 76

Query: 1110 TFLRET--FLNRYV--PFDAAVDFHRLIASTAIVLTVLHSVGHVVNVYLFSISPLSV--- 1162
            +FLR T  F +R +    D  + FH+L+A    + T +H + H+ N   +S S  +    
Sbjct: 77   SFLRGTCSFCSRTLRKQLDHNLTFHKLVAYMICLHTAIHIIAHLFNFDCYSRSRQATDGS 136

Query: 1163 LSCLFPGLFHDD---GSELPQ------KYYWWFFQTVPGLTGVVLLLILAIMYVFASHHF 1213
            L+ +   L HD+   GS L           +  F ++ GLTGV++ + L +M   A+   
Sbjct: 137  LASILSSLSHDEKKGGSWLNPIQSRNTTVEYVTFTSIAGLTGVIMTIALILMVTSATEFI 196

Query: 1214 RRRSFRGFWLTHHLYILLYVLLIIHGSFALIQ---------------------------- 1245
            RR  F  FW THHL+I   + L IHG   +++                            
Sbjct: 197  RRSYFEVFWYTHHLFIFYILGLGIHGIGGIVRGQTEESMNESHPRKCAESFEMWDDRDSH 256

Query: 1246 --LPRFH-------IFFLVPAIIYGGDKLVSLSRKKVEISVVKAELLPSGVTHLRFQRPQ 1296
               P+F         + L P I+Y  ++++   R + ++ + K  + PS V  L+  + +
Sbjct: 257  CRRPKFEGHPPESWKWILAPVILYICERILRFYRSQQKVVITKVVMHPSKVLELQMNK-R 315

Query: 1297 GFEYKSGQWVRIACLALGTTEYHPFTLTSAPHEDTLSLHIRAAGPWTTRLREIYSAPTGD 1356
            GF  + GQ++ + C ++   E+HPFTLTSAP ED  S+HIRAAG WT  L   +      
Sbjct: 316  GFSMEVGQYIFVNCPSISLLEWHPFTLTSAPEEDFFSIHIRAAGDWTENLIRAFE----Q 371

Query: 1357 RCARYPKLYLDGPFGEGHQEWHKFEVSVLVGGGIGVTPFASILKDLVFK-SSVSCQVFCK 1415
            + +  P++ +DGPFG   ++  ++EV+VLVG GIGVTPFASILK + +K       +  K
Sbjct: 372  QYSPIPRIEVDGPFGTASEDVFQYEVAVLVGAGIGVTPFASILKSIWYKFQCADHNLKTK 431

Query: 1416 KIYFIWVTRTQRQFEW----LADIIREVEENDHQDLVSVHIYITQLAEKFDLRTTMLYIC 1471
            KIYF W+ R    F W    L  + +E+EE      ++  +++T         + ++   
Sbjct: 432  KIYFYWICRETGAFSWFNNLLTSLEQEMEELGKVGFLNYRLFLT------GWDSNIVGHA 485

Query: 1472 ERHFQKVLNRSLFTGLRSITHFGRPPFEPFFNSLQEVHPQVRKIGVFSCGPPGMTKNVEK 1531
              +F K  +  + TGL+  T FGRP ++  F+++   HP+   +GVF CGP  + K++ K
Sbjct: 486  ALNFDKATD--IVTGLKQKTSFGRPMWDNEFSTIATSHPK-SVVGVFLCGPRTLAKSLRK 542

Query: 1532 ACQLINRQD--RTHFSHHYENF 1551
             C   +  D  +  F  + ENF
Sbjct: 543  CCHRYSSLDPRKVQFYFNKENF 564


>gi|20127624 NADPH oxidase, EF-hand calcium binding domain 5 [Homo
            sapiens]
          Length = 747

 Score =  231 bits (588), Expect = 5e-60
 Identities = 167/563 (29%), Positives = 270/563 (47%), Gaps = 94/563 (16%)

Query: 1032 QQFKRFIENYRRHIGCVAVFYAIAGGLFLERAYYYAFAAHHTGITDTTRVGIILSRGTAA 1091
            Q  + +  N+R  + C+A +  +   LF       A +AH           +++++G   
Sbjct: 208  QLTRAYWHNHRSQLFCLATYAGLHVLLF-----GLAASAHRD-----LGASVMVAKGCGQ 257

Query: 1092 SISFMFSYILLTMCRNLITFLRETFLNRYVPFDAAVDFHRLIASTAIVLTVLHSVGHVVN 1151
             ++F  S+I + M R  +T+LR T+L + +P D  + FH+L+    + L+++H+V H VN
Sbjct: 258  CLNFDCSFIAVLMLRRCLTWLRATWLAQVLPLDQNIQFHQLMGYVVVGLSLVHTVAHTVN 317

Query: 1152 VYL---FSISPLSVLSCLF---PGLFHDDGSELPQKYYWWFFQTVPGLTGVVLLLILAIM 1205
              L      SP      L    PG+    GS  P              TGV LLL+L +M
Sbjct: 318  FVLQAQAEASPFQFWELLLTTRPGIGWVHGSASP--------------TGVALLLLLLLM 363

Query: 1206 YVFASHHFRRRS-FRGFWLTHHLYILLYVLLIIHGSFALIQLPRFHIFFLVPAIIYGGDK 1264
            ++ +S   RR   F  F+ TH  Y+L+++LLI HG       P F  + LVP I++  +K
Sbjct: 364  FICSSSCIRRSGHFEVFYWTHLSYLLVWLLLIFHG-------PNFWKWLLVPGILFFLEK 416

Query: 1265 LVSLS-RKKVEISVVKAELLPSGVTHLRFQRPQGFEYKSGQWVRIACLALGTTEYHPFTL 1323
             + L+  +   + +++  LLPS VTHL  +RP  F Y+ G ++ +    +   E+HPFT+
Sbjct: 417  AIGLAVSRMAAVCIMEVNLLPSKVTHLLIKRPPFFHYRPGDYLYLNIPTIARYEWHPFTI 476

Query: 1324 TSAPHE-DTLSLHIRAAGPWTTRLREIYSA--PTGDRCARYP------------------ 1362
            +SAP + DT+ LHIR+ G WT RL E + A  P G    R                    
Sbjct: 477  SSAPEQKDTIWLHIRSQGQWTNRLYESFKASDPLGRGSKRLSRSVTMRKSQRSSKGSEIL 536

Query: 1363 ---------KLYLDGPFGEGHQEWHKFEVSVLVGGGIGVTPFASILKDLVFK------SS 1407
                     K Y+DGP+G   +     E +VL+G GIG+TPFASIL+ ++++      + 
Sbjct: 537  LEKHKFCNIKCYIDGPYGTPTRRIFASEHAVLIGAGIGITPFASILQSIMYRHQKRKHTC 596

Query: 1408 VSCQ----------VFCKKIYFIWVTRTQRQFEWLADIIR-----EVEENDHQDLVSVHI 1452
             SCQ          +   K+ FIW+ R QR FEW   ++      + EE  +   + +H+
Sbjct: 597  PSCQHSWIEGVQDNMKLHKVDFIWINRDQRSFEWFVSLLTKLEMDQAEEAQYGRFLELHM 656

Query: 1453 YITQLAEKFDLRTTMLYICERHFQKVLNRSLFTGLRSITHFGRPPFEPFFNSLQEVHPQV 1512
            Y+T    K D++   L +          +   TGL++ T  GRP +   F   Q+V  + 
Sbjct: 657  YMTSALGKNDMKAIGLQMALDLLANKEKKDSITGLQTRTQPGRPDWSKVF---QKVAAEK 713

Query: 1513 R-KIGVFSCGPPGMTKNVEKACQ 1534
            + K+ VF CG P + K ++  C+
Sbjct: 714  KGKVQVFFCGSPALAKVLKGHCE 736



 Score = 54.7 bits (130), Expect = 7e-07
 Identities = 48/186 (25%), Positives = 86/186 (46%), Gaps = 16/186 (8%)

Query: 801 ELSRAEFAESLGLKPQDMFVESMFSLADKDGNGYLSFREFLDILVVFMKGSPEEKSRLMF 860
           E+S  EF  +L +K +  F E  F+L D D +G ++ +E  + L + + GSP +K + +F
Sbjct: 26  EISLQEFKAALHVK-ESFFAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDKLKFLF 84

Query: 861 RMYDFD---GNGLISKDEF-----IRMLRSFIEISNNCLSKAQLAEVVESMFRESGF--- 909
           ++YD D     G  +  E+          S +   +  +   +L  V++S  RES     
Sbjct: 85  QVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGSGSIDPDELRTVLQSCLRESAISLP 144

Query: 910 -QDKEELTWEDFHFMLRDHNSELRFTQLCVKGVEVPEVIKDLCRRASYISQDMICPSPRV 968
            +  ++LT   F     D N  + F +L  +    P V+++L   A++    +  P+PR 
Sbjct: 145 DEKLDQLTLALFESADADGNGAITFEELRDELQRFPGVMENLTISAAHW---LTAPAPRP 201

Query: 969 SARCSR 974
             R  R
Sbjct: 202 RPRRPR 207


>gi|6996021 cytochrome b-245 beta polypeptide [Homo sapiens]
          Length = 570

 Score =  220 bits (561), Expect = 7e-57
 Identities = 157/538 (29%), Positives = 265/538 (49%), Gaps = 86/538 (15%)

Query: 1083 IILSRGTAASISFMFSYILLTMCRNLITFLR------ETFLNRYVPFDAAVDFHRLIAST 1136
            + L+R  AA ++F    ILL +CRNL++FLR       T + R +  D  + FH+++A  
Sbjct: 50   LALARAPAACLNFNCMLILLPVCRNLLSFLRGSSACCSTRVRRQL--DRNLTFHKMVAWM 107

Query: 1137 AIVLTVLHSVGHVVNV-------------YLFSISPLSVLSCLFPGLFHDDGSELPQKYY 1183
              + + +H++ H+ NV             Y  ++S L          F     + P+   
Sbjct: 108  IALHSAIHTIAHLFNVEWCVNARVNNSDPYSVALSELGDRQNESYLNFARKRIKNPEGGL 167

Query: 1184 WWFFQTVPGLTGVVLLLILAIMYVFASHHFRRRSFRGFWLTHHLYILLYVLLIIHGSFAL 1243
            +     + G+TGVV+ L L ++   ++   RR  F  FW THHL+++ ++ L IHG+  +
Sbjct: 168  YLAVTLLAGITGVVITLCLILIITSSTKTIRRSYFEVFWYTHHLFVIFFIGLAIHGAERI 227

Query: 1244 IQ-----------------------------LPRFH-------IFFLVPAIIYGGDKLVS 1267
            ++                             +P+F         + + P  +Y  ++LV 
Sbjct: 228  VRGQTAESLAVHNITVCEQKISEWGKIKECPIPQFAGNPPMTWKWIVGPMFLYLCERLVR 287

Query: 1268 LSRKKVEISVVKAELLPSGVTHLRFQRPQGFEYKSGQWVRIACLALGTTEYHPFTLTSAP 1327
              R + ++ + K    P     L+ ++ +GF+ + GQ++ + C  +   E+HPFTLTSAP
Sbjct: 288  FWRSQQKVVITKVVTHPFKTIELQMKK-KGFKMEVGQYIFVKCPKVSKLEWHPFTLTSAP 346

Query: 1328 HEDTLSLHIRAAGPWTTRLREIYSAPTGDR-----CARYPKLYLDGPFGEGHQEWHKFEV 1382
             ED  S+HIR  G WT  L   ++A   D+       + PK+ +DGPFG   ++   +EV
Sbjct: 347  EEDFFSIHIRIVGDWTEGL---FNACGCDKQEFQDAWKLPKIAVDGPFGTASEDVFSYEV 403

Query: 1383 SVLVGGGIGVTPFASILKDLVFK-SSVSCQVFCKKIYFIWVTRTQRQFEWLADIIR---- 1437
             +LVG GIGVTPFASILK + +K  + +  +  KKIYF W+ R    FEW AD+++    
Sbjct: 404  VMLVGAGIGVTPFASILKSVWYKYCNNATNLKLKKIYFYWLCRDTHAFEWFADLLQLLES 463

Query: 1438 EVEENDHQDLVSVHIYITQLAEKFDLRTTMLYICERHFQKVLNRSLFTGLRSITHFGRPP 1497
            +++E ++   +S +IY+T   E     +   +    H ++   + + TGL+  T +GRP 
Sbjct: 464  QMQERNNAGFLSYNIYLTGWDE-----SQANHFAVHHDEE---KDVITGLKQKTLYGRPN 515

Query: 1498 FEPFFNSLQEVHPQVRKIGVFSCGPPGMTKNVEKACQLINRQDR----THFSHHYENF 1551
            ++  F ++   HP  R IGVF CGP  + + + K  Q I+  +      HF  + ENF
Sbjct: 516  WDNEFKTIASQHPNTR-IGVFLCGPEALAETLSK--QSISNSESGPRGVHFIFNKENF 570


>gi|7669510 NADPH oxidase 1 isoform long variant [Homo sapiens]
          Length = 515

 Score =  207 bits (527), Expect = 6e-53
 Identities = 160/557 (28%), Positives = 256/557 (45%), Gaps = 119/557 (21%)

Query: 1050 VFYAIAGGLFLERAYYYAFAAHHTGITDTTRVGIILSRGTAASISFMFSYILLTMCRNLI 1109
            VF  +   L  E+A  Y +     G T      +  +R +A  ++F  + ILL +CRNL+
Sbjct: 23   VFLFVDAFLKYEKADKYYYTRKILGST------LACARASALCLNFNSTLILLPVCRNLL 76

Query: 1110 TFLRET--FLNRYV--PFDAAVDFHRLIASTAIVLTVLHSVGHVVNVYLFSISPLSV--- 1162
            +FLR T  F +R +    D  + FH+L+A    + T +H + H+ N   +S S  +    
Sbjct: 77   SFLRGTCSFCSRTLRKQLDHNLTFHKLVAYMICLHTAIHIIAHLFNFDCYSRSRQATDGS 136

Query: 1163 LSCLFPGLFHDD---GSELPQ------KYYWWFFQTVPGLTGVVLLLILAIMYVFASHHF 1213
            L+ +   L HD+   GS L           +  F ++ GLTGV++ + L +M   A+   
Sbjct: 137  LASILSSLSHDEKKGGSWLNPIQSRNTTVEYVTFTSIAGLTGVIMTIALILMVTSATEFI 196

Query: 1214 RRRSFRGFWLTHHLYILLYVLLIIHGSFALIQ---------------------------- 1245
            RR  F  FW THHL+I   + L IHG   +++                            
Sbjct: 197  RRSYFEVFWYTHHLFIFYILGLGIHGIGGIVRGQTEESMNESHPRKCAESFEMWDDRDSH 256

Query: 1246 --LPRFH-------IFFLVPAIIYGGDKLVSLSRKKVEISVVKAELLPSGVTHLRFQRPQ 1296
               P+F         + L P I+Y  ++++   R + ++ + K  + PS V  L+  + +
Sbjct: 257  CRRPKFEGHPPESWKWILAPVILYICERILRFYRSQQKVVITKVVMHPSKVLELQMNK-R 315

Query: 1297 GFEYKSGQWVRIACLALGTTEYHPFTLTSAPHEDTLSLHIRAAGPWTTRLREIYSAPTGD 1356
            GF  + GQ++ + C ++   E+HPFTLTSAP ED  S+HIRAAG WT  L   +      
Sbjct: 316  GFSMEVGQYIFVNCPSISLLEWHPFTLTSAPEEDFFSIHIRAAGDWTENLIRAFE----Q 371

Query: 1357 RCARYPKLYLDGPFGEGHQEWHKFEVSVLVGGGIGVTPFASILKDLVFKSSVSCQVFCKK 1416
            + +  P++ +DGPFG   ++  ++EV+VLVG GIGVTPFASILK + +K   +       
Sbjct: 372  QYSPIPRIEVDGPFGTASEDVFQYEVAVLVGAGIGVTPFASILKSIWYKFQCA------- 424

Query: 1417 IYFIWVTRTQRQFEWLADIIREVEENDHQDLVSVHIYITQLAEKFDLRTTMLYICERHFQ 1476
                                      DH                 +L+T  +     +F 
Sbjct: 425  --------------------------DH-----------------NLKTKKVGHAALNFD 441

Query: 1477 KVLNRSLFTGLRSITHFGRPPFEPFFNSLQEVHPQVRKIGVFSCGPPGMTKNVEKACQLI 1536
            K  +  + TGL+  T FGRP ++  F+++   HP+   +GVF CGP  + K++ K C   
Sbjct: 442  KATD--IVTGLKQKTSFGRPMWDNEFSTIATSHPK-SVVGVFLCGPRTLAKSLRKCCHRY 498

Query: 1537 NRQD--RTHFSHHYENF 1551
            +  D  +  F  + ENF
Sbjct: 499  SSLDPRKVQFYFNKENF 515


>gi|126517478 peroxidasin homolog-like [Homo sapiens]
          Length = 1463

 Score =  164 bits (416), Expect = 5e-40
 Identities = 155/550 (28%), Positives = 241/550 (43%), Gaps = 64/550 (11%)

Query: 33   DGWYNNLMEHRWGSKGSRLQRLVPASYADGVYQPLG-------EPHLPNPRDLSNTISRG 85
            DG  NNL +  WG+  +   RL+  +Y DG+  P G          LP PR ++   +R 
Sbjct: 731  DGTCNNLQQPTWGAALTAFARLLQPAYRDGIRAPRGLGLPVGSRQPLPPPRLVATVWARA 790

Query: 86   PAGLASLRNRTVLGVFFGYHVLSDL--------VSVETPGCPAEFLNIRIPPGDPM---- 133
             A +    + T + + +G+ +  DL         +  + G P   +    PP  PM    
Sbjct: 791  -AAVTPDHSYTRMLMHWGWFLEHDLDHTVPALSTARFSDGRPCSSVCTNDPPCFPMNTRH 849

Query: 134  FDPDQRGDVVLPFQRSRWDPETGRSPSN-----PRDPANQVTGWLDGSAIYGSSHSWSDA 188
             DP       + F RS     +GR  +       R+  NQ T ++DGS +YGSS   S A
Sbjct: 850  ADPRGTHAPCMLFARSSPACASGRPSATVDSVYAREQINQQTAYIDGSNVYGSSERESQA 909

Query: 189  LR--SFSRGQLASGPDPAFP-RDSQNPLLMWAA--PDPATGQNGPRGLYAFGAERGNREP 243
            LR  S  RG L +G    FP   S  PLL ++   P     Q      +  G  R N   
Sbjct: 910  LRDPSVPRGLLKTG----FPWPPSGKPLLPFSTGPPTECARQEQESPCFLAGDHRANEHL 965

Query: 244  FLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAVYEWLPSFL--- 300
             L A+  LWFR HN  A  L+  +P WE   ++Q ARK V A  Q+I    WLP  L   
Sbjct: 966  ALAAMHTLWFREHNRVATELSALNPHWEGNTVYQEARKIVGAELQHITYSHWLPKVLGDP 1025

Query: 301  -QKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVPPGVYMRNASCH--FQGVINRNSSV 357
              + L  Y GY P ++  I + F  A+ +F  T++ P +Y  NA+     +G +  + ++
Sbjct: 1026 GTRMLRGYRGYNPNVNAGIINSFATAAFRFGHTLINPILYRLNATLGEISEGHLPFHKAL 1085

Query: 358  SRALRVCNSYWSREHPSLQSAEDVDALLLGMASQIAE--REDHVLVEDVRDFWPGPLKFS 415
                R+                 +D +L G+    A+     ++L  ++          +
Sbjct: 1086 FSPSRIIKE------------GGIDPVLRGLFGVAAKWRAPSYLLSPELTQRLFSAAYSA 1133

Query: 416  RTDHLASCLQRGRDLGLPSYTKARAALGLSPITRWQDINPALSRSNDTVLEATAALYNQ- 474
              D  A+ +QRGRD G+P Y   R    L+ +  ++D+   +  S   + +    LY   
Sbjct: 1134 AVDSAATIIQRGRDHGIPPYVDFRVFCNLTSVKNFEDLQNEIKDSE--IRQKLRKLYGSP 1191

Query: 475  ---DLSWLELLPGGLLESHRDPGPLFSTIVLEQFVRLRDGDRYWFENTRNGLFSKKEIEE 531
               DL W  L+   L+   R  GP    + + QF RLRDGDR+W+EN   G+F+  ++ +
Sbjct: 1192 GDIDL-WPALMVEDLIPGTR-VGPTLMCLFVTQFQRLRDGDRFWYENP--GVFTPAQLTQ 1247

Query: 532  IRNTTLQDVL 541
            ++  +L  VL
Sbjct: 1248 LKQASLSRVL 1257


>gi|109150416 peroxidasin [Homo sapiens]
          Length = 1479

 Score =  155 bits (391), Expect = 4e-37
 Identities = 153/559 (27%), Positives = 239/559 (42%), Gaps = 79/559 (14%)

Query: 33   DGWYNNLMEHRWGSKGSRLQRLVPASYADGVYQPLG-EPH-------LPNPRDLSNTISR 84
            DG  NNL    WG+  +  +RL+ + Y +G   P G  PH       LP PR +S T+  
Sbjct: 745  DGTCNNLQHPMWGASLTAFERLLKSVYENGFNTPRGINPHRLYNGHALPMPRLVSTTLI- 803

Query: 85   GPAGLASLRNRTVLGVFFGYHVLSDLVSVETPGCPAEF----------------LNIRIP 128
            G   +      T + + +G  +  DL S       A F                 ++ IP
Sbjct: 804  GTETVTPDEQFTHMLMQWGQFLDHDLDSTVVALSQARFSDGQHCSNVCSNDPPCFSVMIP 863

Query: 129  PGDPMFDPDQRGDVVLPFQRSRWDPETGRSPSN-------PRDPANQVTGWLDGSAIYGS 181
            P D      + G   + F RS   P  G   ++       PR+  NQ+T ++D S +YGS
Sbjct: 864  PNDSRA---RSGARCMFFVRS--SPVCGSGMTSLLMNSVYPREQINQLTSYIDASNVYGS 918

Query: 182  SHSWSDALRSFS--RGQLASGPDPAFPRDSQNPLLMWAAPDPAT----GQNGPRGLYAFG 235
            +   + ++R  +  RG L  G      + S  PLL +A   P          P   +  G
Sbjct: 919  TEHEARSIRDLASHRGLLRQG----IVQRSGKPLLPFATGPPTECMRDENESPIPCFLAG 974

Query: 236  AERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAVYEW 295
              R N +  L ++  LWFR HN  A  L + +P W+ + ++   RK V A  Q+I    W
Sbjct: 975  DHRANEQLGLTSMHTLWFREHNRIATELLKLNPHWDGDTIYYETRKIVGAEIQHITYQHW 1034

Query: 296  LPSFL----QKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVPPGVYMRNASCHFQGVI 351
            LP  L     +TL EY GY P ++  I + F  A+ +F  T+V P +Y  +   +FQ + 
Sbjct: 1035 LPKILGEVGMRTLGEYHGYDPGINAGIFNAFATAAFRFGHTLVNPLLYRLDE--NFQPIA 1092

Query: 352  NRNSSVSRA----LRVCNSYWSREHPSLQSAEDVDALLLGMASQIAERE--DHVLVEDVR 405
              +  + +A     R+ N               +D LL G+     +      +L  ++ 
Sbjct: 1093 QDHLPLHKAFFSPFRIVNE------------GGIDPLLRGLFGVAGKMRVPSQLLNTELT 1140

Query: 406  DFWPGPLKFSRTDHLASCLQRGRDLGLPSYTKARAALGLSPITRWQDINPALSRSNDTVL 465
            +           D  A  +QRGRD G+P Y   R    LS    ++D+   +   N  + 
Sbjct: 1141 ERLFSMAHTVALDLAAINIQRGRDHGIPPYHDYRVYCNLSAAHTFEDLKNEI--KNPEIR 1198

Query: 466  EATAALYNQDLSWLELLPGGLLES---HRDPGPLFSTIVLEQFVRLRDGDRYWFENTRNG 522
            E    LY   L+ ++L P  ++E        GP    ++  QF RLRDGDR W+EN   G
Sbjct: 1199 EKLKRLYGSTLN-IDLFPALVVEDLVPGSRLGPTLMCLLSTQFKRLRDGDRLWYENP--G 1255

Query: 523  LFSKKEIEEIRNTTLQDVL 541
            +FS  ++ +I+ T+L  +L
Sbjct: 1256 VFSPAQLTQIKQTSLARIL 1274


>gi|219842348 NADPH oxidase 4 isoform c [Homo sapiens]
          Length = 554

 Score =  149 bits (377), Expect = 2e-35
 Identities = 99/358 (27%), Positives = 167/358 (46%), Gaps = 36/358 (10%)

Query: 1208 FASHHFRRRSFRGFWLTHHLYILLYVLLIIHGSFALIQLPRFHIFFLVPAIIYGGDKLVS 1267
            + S HF      GF          +V + +         P+  ++   P  +Y  ++L  
Sbjct: 218  YFSEHFHEPFPEGFSKPAEFTQHKFVKICMEEPRFQANFPQTWLWISGPLCLYCAERLYR 277

Query: 1268 LSRKKVEISVVKAELLPSGVTHLRFQRPQGFEYKSGQWVRIACLALGTTEYHPFTLTSAP 1327
              R    ++++     PS V  +R  + + F+ + GQ++ + C ++   E HPFTLT  P
Sbjct: 278  YIRSNKPVTIISVISHPSDVMEIRMVK-ENFKARPGQYITLHCPSVSALENHPFTLTMCP 336

Query: 1328 HED--TLSLHIRAAGPWTTRLREIYSAPTGD--------RCARYPKLYLDGPFGEGHQEW 1377
             E   T  +H++  G WT R R++   P+          +   YPKLY+DGPFG   +E 
Sbjct: 337  TETKATFGVHLKIVGDWTERFRDLLLPPSSQDSEILPFIQSRNYPKLYIDGPFGSPFEES 396

Query: 1378 HKFEVSVLVGGGIGVTPFASILKDLVFKSSVSCQVFCKKIYFIWVTRTQRQFEWLADII- 1436
              +EVS+ V GGIGVTPFASIL  L+           +++YFIWV R  + F W AD++ 
Sbjct: 397  LNYEVSLCVAGGIGVTPFASILNTLLDDWK---PYKLRRLYFIWVCRDIQSFRWFADLLC 453

Query: 1437 ---REVEENDHQDLVSVHIYITQLAEKFDLRTTMLYICERHFQKVLNRSLFTGLRSITHF 1493
                +  + +  D V++ +Y++Q                   QK++    +  L S    
Sbjct: 454  MLHNKFWQENRPDYVNIQLYLSQ---------------TDGIQKIIGEK-YHALNSRLFI 497

Query: 1494 GRPPFEPFFNSLQEVHPQVRKIGVFSCGPPGMTKNVEKACQLINRQDRTHFSHHYENF 1551
            GRP ++  F+ + + + + + +GVF CGP  ++K + K     N    T F ++ E+F
Sbjct: 498  GRPRWKLLFDEIAK-YNRGKTVGVFCCGPNSLSKTLHKLSNQ-NNSYGTRFEYNKESF 553



 Score = 84.0 bits (206), Expect = 1e-15
 Identities = 54/172 (31%), Positives = 91/172 (52%), Gaps = 16/172 (9%)

Query: 1081 VGIILSRGTAASISFMFSYILLTMCRNLITFLRETFLNRYVP-------FDAAVDFHRLI 1133
            +G+ LSR +A+ ++   S ILL MCR L+ +LR +   + VP        D +  FH   
Sbjct: 28   LGLCLSRASASVLNLNCSLILLPMCRTLLAYLRGS---QKVPSRRTRRLLDKSRTFHITC 84

Query: 1134 ASTAIVLTVLHSVGHVVNVYLFSISPLSVLSCLFPGLFHDDGSELPQKYYWWFFQTVPGL 1193
              T  + + +H   H+VN   FS++       L    + D+    P+K     F TVPGL
Sbjct: 85   GVTICIFSGVHVAAHLVNALNFSVNYSEDFVELNAARYRDED---PRKL---LFTTVPGL 138

Query: 1194 TGVVLLLILAIMYVFASHHFRRRSFRGFWLTHHLYILLYVLLIIHGSFALIQ 1245
            TGV ++++L +M   +++  R  ++  FW TH+L+ + Y+LL +H S  L++
Sbjct: 139  TGVCMVVVLFLMITASTYAIRVSNYDIFWYTHNLFFVFYMLLTLHVSGGLLK 190


>gi|8393843 NADPH oxidase 4 isoform a [Homo sapiens]
          Length = 578

 Score =  149 bits (377), Expect = 2e-35
 Identities = 99/358 (27%), Positives = 167/358 (46%), Gaps = 36/358 (10%)

Query: 1208 FASHHFRRRSFRGFWLTHHLYILLYVLLIIHGSFALIQLPRFHIFFLVPAIIYGGDKLVS 1267
            + S HF      GF          +V + +         P+  ++   P  +Y  ++L  
Sbjct: 242  YFSEHFHEPFPEGFSKPAEFTQHKFVKICMEEPRFQANFPQTWLWISGPLCLYCAERLYR 301

Query: 1268 LSRKKVEISVVKAELLPSGVTHLRFQRPQGFEYKSGQWVRIACLALGTTEYHPFTLTSAP 1327
              R    ++++     PS V  +R  + + F+ + GQ++ + C ++   E HPFTLT  P
Sbjct: 302  YIRSNKPVTIISVISHPSDVMEIRMVK-ENFKARPGQYITLHCPSVSALENHPFTLTMCP 360

Query: 1328 HED--TLSLHIRAAGPWTTRLREIYSAPTGD--------RCARYPKLYLDGPFGEGHQEW 1377
             E   T  +H++  G WT R R++   P+          +   YPKLY+DGPFG   +E 
Sbjct: 361  TETKATFGVHLKIVGDWTERFRDLLLPPSSQDSEILPFIQSRNYPKLYIDGPFGSPFEES 420

Query: 1378 HKFEVSVLVGGGIGVTPFASILKDLVFKSSVSCQVFCKKIYFIWVTRTQRQFEWLADII- 1436
              +EVS+ V GGIGVTPFASIL  L+           +++YFIWV R  + F W AD++ 
Sbjct: 421  LNYEVSLCVAGGIGVTPFASILNTLLDDWK---PYKLRRLYFIWVCRDIQSFRWFADLLC 477

Query: 1437 ---REVEENDHQDLVSVHIYITQLAEKFDLRTTMLYICERHFQKVLNRSLFTGLRSITHF 1493
                +  + +  D V++ +Y++Q                   QK++    +  L S    
Sbjct: 478  MLHNKFWQENRPDYVNIQLYLSQ---------------TDGIQKIIGEK-YHALNSRLFI 521

Query: 1494 GRPPFEPFFNSLQEVHPQVRKIGVFSCGPPGMTKNVEKACQLINRQDRTHFSHHYENF 1551
            GRP ++  F+ + + + + + +GVF CGP  ++K + K     N    T F ++ E+F
Sbjct: 522  GRPRWKLLFDEIAK-YNRGKTVGVFCCGPNSLSKTLHKLSNQ-NNSYGTRFEYNKESF 577



 Score = 84.7 bits (208), Expect = 6e-16
 Identities = 58/206 (28%), Positives = 103/206 (50%), Gaps = 16/206 (7%)

Query: 1047 CVAVFYAIAGGLFLERAYYYAFAAHHTGITDTTRVGIILSRGTAASISFMFSYILLTMCR 1106
            C+ ++ ++   LF +    Y     +  +     +G+ LSR +A+ ++   S ILL MCR
Sbjct: 18   CLFIWLSMNVLLFWKTFLLYNQGPEYHYLHQMLGLGLCLSRASASVLNLNCSLILLPMCR 77

Query: 1107 NLITFLRETFLNRYVP-------FDAAVDFHRLIASTAIVLTVLHSVGHVVNVYLFSISP 1159
             L+ +LR +   + VP        D +  FH     T  + + +H   H+VN   FS++ 
Sbjct: 78   TLLAYLRGS---QKVPSRRTRRLLDKSRTFHITCGVTICIFSGVHVAAHLVNALNFSVNY 134

Query: 1160 LSVLSCLFPGLFHDDGSELPQKYYWWFFQTVPGLTGVVLLLILAIMYVFASHHFRRRSFR 1219
                  L    + D+    P+K     F TVPGLTGV ++++L +M   +++  R  ++ 
Sbjct: 135  SEDFVELNAARYRDED---PRKL---LFTTVPGLTGVCMVVVLFLMITASTYAIRVSNYD 188

Query: 1220 GFWLTHHLYILLYVLLIIHGSFALIQ 1245
             FW TH+L+ + Y+LL +H S  L++
Sbjct: 189  IFWYTHNLFFVFYMLLTLHVSGGLLK 214


>gi|4503595 eosinophil peroxidase [Homo sapiens]
          Length = 715

 Score =  139 bits (351), Expect = 2e-32
 Identities = 154/548 (28%), Positives = 247/548 (45%), Gaps = 62/548 (11%)

Query: 34  GWYNNLMEHRWGSKGSRLQRLVPASYADGVYQPLGEPH--------LPNPRDLSNTISRG 85
           G  NN      G+    L R +PA Y DG+  P G           LP  R +SN I R 
Sbjct: 150 GRCNNKRRPLLGASNQALARWLPAEYEDGLSLPFGWTPSRRRNGFLLPLVRAVSNQIVRF 209

Query: 86  P-AGLASLRNRTVLGVFFGYHVLSDL-VSVETPGCPA---------------EFLNIRIP 128
           P   L S R R ++ + +G  +  DL  S E+P   A                   I+IP
Sbjct: 210 PNERLTSDRGRALMFMQWGQFIDHDLDFSPESPARVAFTAGVDCERTCAQLPPCFPIKIP 269

Query: 129 PGDPMFDPDQRGDVVLPFQRSRWDPETGRSPSNPRDPANQVTGWLDGSAIYGSSHSWSDA 188
           P DP    +QR    +PF RS   P   ++ +  R+  N +T ++D S +YGS  S S  
Sbjct: 270 PNDPRIK-NQRD--CIPFFRSA--PSCPQNKNRVRNQINALTSFVDASMVYGSEVSLSLR 324

Query: 189 LRSFSRGQLASGPDPAFPRDSQNPLLMW--AAPDPATGQNGPRGLYAF--GAERGNREPF 244
           LR+ +        +  F +D+   LL +     DP    N    +  F  G  R    P 
Sbjct: 325 LRNRTNYLGLLAINQRF-QDNGRALLPFDNLHDDPCLLTNRSARIPCFLAGDTRSTETPK 383

Query: 245 LQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAVYEWLPSFL---- 300
           L A+  L+ R HN  A  L R +P W  ++L+  ARK + A  Q I   ++LP  L    
Sbjct: 384 LAAMHTLFMREHNRLATELRRLNPRWNGDKLYNEARKIMGAMVQIITYRDFLPLVLGKAR 443

Query: 301 -QKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVPPGVYMRNASCHFQGVINRNSSVSR 359
            ++TL  Y GY   +DP +++ F  A  +F  TM+ P ++  ++         R S+ + 
Sbjct: 444 ARRTLGHYRGYCSNVDPRVANVFTLAF-RFGHTMLQPFMFRLDSQ-------YRASAPNS 495

Query: 360 ALRVCNSYWSREHPSLQSAEDVDALLLGMASQIAE--REDHVLVEDVRDFWPGPLKFSRT 417
            + + +++++      +    +D +L G+ +  A+  R+D +LV+++RD     ++    
Sbjct: 496 HVPLSSAFFASWRIVYEGG--IDPILRGLMATPAKLNRQDAMLVDELRDRLFRQVRRIGL 553

Query: 418 DHLASCLQRGRDLGLPSYTKARAALGLSPITRWQDINPALSRSNDTVLEATAALY----N 473
           D  A  +QR RD GLP Y   R   GLS       ++  L   N  +      LY    N
Sbjct: 554 DLAALNMQRSRDHGLPGYNAWRRFCGLSQPRNLAQLSRVL--KNQDLARKFLNLYGTPDN 611

Query: 474 QDLSWLELLPGGLLESHRDPGPLFSTIVLEQFVRLRDGDRYWFENTRNGLFSKKEIEEIR 533
            D+ W+  +   LL   R  GPL + +   QF R RDGDR+W++  + G+F+K++ + + 
Sbjct: 612 IDI-WIGAIAEPLLPGAR-VGPLLACLFENQFRRARDGDRFWWQ--KRGVFTKRQRKALS 667

Query: 534 NTTLQDVL 541
             +L  ++
Sbjct: 668 RISLSRII 675


>gi|28558982 thyroid peroxidase isoform a [Homo sapiens]
          Length = 933

 Score =  130 bits (328), Expect = 8e-30
 Identities = 155/561 (27%), Positives = 241/561 (42%), Gaps = 74/561 (13%)

Query: 34  GWYNNLMEHRWGSKGSRLQRLVPASYADGVYQPLGEPHLPNPRDLSNTISRGPAG----- 88
           G  NN    RWG+  + L R +P  Y DG  QP G     NP  L N     P       
Sbjct: 156 GACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGW----NPGFLYNGFPLPPVREVTRH 211

Query: 89  LASLRNRTV--------LGVFFGYHVLSDLVSVETPGCPAEF-----LNIRIPPGDPMFD 135
           +  + N  V        L + +G ++  D+         A F       +     +P F 
Sbjct: 212 VIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNPCFP 271

Query: 136 ---PDQR----GDVVLPFQRSRWDPETGR--------SPSNPRDPANQVTGWLDGSAIYG 180
              P++     G   LPF RS     TG         S +NPR   N +T +LD S +YG
Sbjct: 272 IQLPEEARPAAGTACLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDASTVYG 331

Query: 181 SSHSWSDALRSFSRGQLASGPDPAFPRDSQNPLLMWA--------APDPATGQNGPRGLY 232
           SS +    LR+++  +          RDS    L +         AP+P          +
Sbjct: 332 SSPALERQLRNWTSAEGLLRVHARL-RDSGRAYLPFVPPRAPAACAPEPGIPGETRGPCF 390

Query: 233 AFGAERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAV 292
             G  R +  P L AL  LW R HN  A  L   +  W  + ++Q ARK V A +Q I +
Sbjct: 391 LAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITL 450

Query: 293 YEWLPSFL-----QKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVPPGVYMRNASCHF 347
            +++P  L     Q+ +  Y GY    +P++S+ F  A+ +F    + P V   +AS  F
Sbjct: 451 RDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDAS--F 508

Query: 348 QGVINRNSSVSRALRVCNSYWSREHPSLQSAEDVDALLLGMASQIA--EREDHVLVEDVR 405
           Q            L +  +++S    +L     +D L+ G+ ++ A  + +D ++ E++ 
Sbjct: 509 Q-----EHPDLPGLWLHQAFFSPW--TLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELT 561

Query: 406 DFWPGPLKFSRTDHLASCLQRGRDLGLPSYTKARAALGLSPITRWQDINPAL-SRS-NDT 463
           +        S  D  +  LQRGRD GLP Y + R   GL  +    D++ A+ SRS  D 
Sbjct: 562 ERLFVLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADK 621

Query: 464 VLEATAALYNQDLSWLELLPGGLLES---HRDPGPLFSTIVLEQFVRLRDGDRYWFENTR 520
           +L+      N D+ WL    GGL E+       GPLF+ ++ +Q   LRDGD +W+EN+ 
Sbjct: 622 ILDLYKHPDNIDV-WL----GGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSH 676

Query: 521 NGLFSKKEIEEIRNTTLQDVL 541
             +F+  +  E+   +L  V+
Sbjct: 677 --VFTDAQRRELEKHSLSRVI 695


>gi|28558988 thyroid peroxidase isoform d [Homo sapiens]
          Length = 889

 Score =  130 bits (328), Expect = 8e-30
 Identities = 155/561 (27%), Positives = 241/561 (42%), Gaps = 74/561 (13%)

Query: 34  GWYNNLMEHRWGSKGSRLQRLVPASYADGVYQPLGEPHLPNPRDLSNTISRGPAG----- 88
           G  NN    RWG+  + L R +P  Y DG  QP G     NP  L N     P       
Sbjct: 156 GACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGW----NPGFLYNGFPLPPVREVTRH 211

Query: 89  LASLRNRTV--------LGVFFGYHVLSDLVSVETPGCPAEF-----LNIRIPPGDPMFD 135
           +  + N  V        L + +G ++  D+         A F       +     +P F 
Sbjct: 212 VIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNPCFP 271

Query: 136 ---PDQR----GDVVLPFQRSRWDPETGR--------SPSNPRDPANQVTGWLDGSAIYG 180
              P++     G   LPF RS     TG         S +NPR   N +T +LD S +YG
Sbjct: 272 IQLPEEARPAAGTACLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDASTVYG 331

Query: 181 SSHSWSDALRSFSRGQLASGPDPAFPRDSQNPLLMWA--------APDPATGQNGPRGLY 232
           SS +    LR+++  +          RDS    L +         AP+P          +
Sbjct: 332 SSPALERQLRNWTSAEGLLRVHARL-RDSGRAYLPFVPPRAPAACAPEPGIPGETRGPCF 390

Query: 233 AFGAERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAV 292
             G  R +  P L AL  LW R HN  A  L   +  W  + ++Q ARK V A +Q I +
Sbjct: 391 LAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITL 450

Query: 293 YEWLPSFL-----QKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVPPGVYMRNASCHF 347
            +++P  L     Q+ +  Y GY    +P++S+ F  A+ +F    + P V   +AS  F
Sbjct: 451 RDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDAS--F 508

Query: 348 QGVINRNSSVSRALRVCNSYWSREHPSLQSAEDVDALLLGMASQIA--EREDHVLVEDVR 405
           Q            L +  +++S    +L     +D L+ G+ ++ A  + +D ++ E++ 
Sbjct: 509 Q-----EHPDLPGLWLHQAFFSPW--TLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELT 561

Query: 406 DFWPGPLKFSRTDHLASCLQRGRDLGLPSYTKARAALGLSPITRWQDINPAL-SRS-NDT 463
           +        S  D  +  LQRGRD GLP Y + R   GL  +    D++ A+ SRS  D 
Sbjct: 562 ERLFVLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADK 621

Query: 464 VLEATAALYNQDLSWLELLPGGLLES---HRDPGPLFSTIVLEQFVRLRDGDRYWFENTR 520
           +L+      N D+ WL    GGL E+       GPLF+ ++ +Q   LRDGD +W+EN+ 
Sbjct: 622 ILDLYKHPDNIDV-WL----GGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSH 676

Query: 521 NGLFSKKEIEEIRNTTLQDVL 541
             +F+  +  E+   +L  V+
Sbjct: 677 --VFTDAQRRELEKHSLSRVI 695


>gi|4557759 myeloperoxidase [Homo sapiens]
          Length = 745

 Score =  124 bits (311), Expect = 7e-28
 Identities = 151/568 (26%), Positives = 242/568 (42%), Gaps = 64/568 (11%)

Query: 15  AWTPLGAQNPISWEVQRFDGWYNNLMEHRWGSKGSRLQRLVPASYADGVYQPLG-EPHLP 73
           A+  +G   P   + +   G  NN      G+      R +PA Y DG   P G  P + 
Sbjct: 159 AYQDVGVTCPEQDKYRTITGMCNNRRSPTLGASNRAFVRWLPAEYEDGFSLPYGWTPGVK 218

Query: 74  N-------PRDLSNTISRGPAG-LASLRNRTVLGVFFGYHVLSDLVSVETPGCPAEFLN- 124
                    R +SN I R P   L   + R+++ + +G  +  DL     P   A F+  
Sbjct: 219 RNGFPVALARAVSNEIVRFPTDQLTPDQERSLMFMQWGQLLDHDLDFTPEPAARASFVTG 278

Query: 125 ---------------IRIPPGDPMFDPDQRGDVVLPFQRSRWDPETGRSPSNPRDPANQV 169
                          ++IPP DP      + D + PF RS   P    S    R+  N +
Sbjct: 279 VNCETSCVQQPPCFPLKIPPNDPRIK--NQADCI-PFFRSC--PACPGSNITIRNQINAL 333

Query: 170 TGWLDGSAIYGSSHSWSDALRSFSRGQLASGPDPAFPRDSQNPLLMW--AAPDPATGQNG 227
           T ++D S +YGS    +  LR+ S        +  F +D+   LL +     DP    N 
Sbjct: 334 TSFVDASMVYGSEEPLARNLRNMSNQLGLLAVNQRF-QDNGRALLPFDNLHDDPCLLTNR 392

Query: 228 PRGLYAF--GAERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVIA 285
              +  F  G  R +  P L ++  L  R HN  A  L   +P W+ E L+Q ARK V A
Sbjct: 393 SARIPCFLAGDTRSSEMPELTSMHTLLLREHNRLATELKSLNPRWDGERLYQEARKIVGA 452

Query: 286 TYQNIAVYEWL-----PSFLQKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVPPGVYM 340
             Q I   ++L     P+ ++K LP Y  Y   +DP I++ F  A  ++  T++ P  +M
Sbjct: 453 MVQIITYRDYLPLVLGPTAMRKYLPTYRSYNDSVDPRIANVFTNAF-RYGHTLIQP--FM 509

Query: 341 RNASCHFQGVINRNSSVSRALRVCNSYWSREHPSLQSAEDVDALLLGMASQIAE--REDH 398
                 +Q  +  N  V  + RV  + W      +     +D +L G+ +  A+  R++ 
Sbjct: 510 FRLDNRYQ-PMEPNPRVPLS-RVFFASW-----RVVLEGGIDPILRGLMATPAKLNRQNQ 562

Query: 399 VLVEDVRDFWPGPLKFSRTDHLASCLQRGRDLGLPSYTKARAALGLSPITRWQDINPALS 458
           + V+++R+     +     D  A  +QR RD GLP Y   R   GL        +   L 
Sbjct: 563 IAVDEIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNAWRRFCGLPQPETVGQLGTVLR 622

Query: 459 --RSNDTVLEATAALYNQDLSWLELLPGGLLESHRDP---GPLFSTIVLEQFVRLRDGDR 513
             +    ++E      N D+ W+    GG+ E  +     GPL + I+  QF +LRDGDR
Sbjct: 623 NLKLARKLMEQYGTPNNIDI-WM----GGVSEPLKRKGRVGPLLACIIGTQFRKLRDGDR 677

Query: 514 YWFENTRNGLFSKKEIEEIRNTTLQDVL 541
           +W+EN   G+FS ++ + +   +L  ++
Sbjct: 678 FWWEN--EGVFSMQQRQALAQISLPRII 703


>gi|231569458 lactoperoxidase isoform 3 preproprotein [Homo sapiens]
          Length = 629

 Score =  121 bits (304), Expect = 5e-27
 Identities = 148/565 (26%), Positives = 245/565 (43%), Gaps = 71/565 (12%)

Query: 14  GAWTPLGAQNPISWEVQRFDGWYNNLMEHRWGSKGSRLQRLVPASYADGVYQPLGEPH-- 71
           GA  P+   +P S   +   G  NN  +   G+    L R +PA Y DG+  P G     
Sbjct: 41  GAPAPVVRCDPCS-PYRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGK 99

Query: 72  ------LPNPRDLSNTISR--GPAGLASLRNRTVLGVFFGYHVLSDL-VSVETPGCPAEF 122
                 LP  R++SN I       G+   +NR++L + +G  V  DL  + +T    +E+
Sbjct: 100 TRNGFPLPLAREVSNKIVGYLNEEGVLD-QNRSLLFMQWGQIVDHDLDFAPDTELGSSEY 158

Query: 123 LN---------------IRIPPGDPMFDPDQRGDVVLPFQRSRWDPETGRSPSNPRDPAN 167
                            I  PP DP      +    +PF R+ +   T    S  R+  N
Sbjct: 159 SKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGK---CMPFFRAGFVCPTPPYKSLAREQIN 215

Query: 168 QVTGWLDGSAIYGSSHSWSDALRSFSR--GQLASGPD------PAFPRDSQNPLLMWAAP 219
            +T +LD S +Y S  S +  LR+ S   G +A   +      P  P DS+ P     +P
Sbjct: 216 ALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSKKP-----SP 270

Query: 220 DPATGQNGPRGLYAFGAERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHA 279
                       +  G  R +    L     L+ R HN  A+ L R +P W+ E+L+Q A
Sbjct: 271 CEFINTTARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEA 330

Query: 280 RKRVIATYQNIAVYEWLPSFL----QKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVP 335
           RK + A  Q I   ++LP  L    QK +P Y GY   +DP IS+ F  A  +F    VP
Sbjct: 331 RKILGAFVQIITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVFTFAF-RFGHLEVP 389

Query: 336 PGVYMRNASCHFQGVINRNSSVSRALRVCNSYWSREHPSLQSAEDVDALLLGMASQIAE- 394
             ++  + +    G       +       N++       +     +D L+ G+ ++ ++ 
Sbjct: 390 SSMFRLDENYQPWG---PEPELPLHTLFFNTW------RMVKDGGIDPLVRGLLAKKSKL 440

Query: 395 -REDHVLVEDVRDFWPGPL-KFSRTDHLASCLQRGRDLGLPSYTKARAALGLSPITRWQD 452
            +++ ++  ++R+    P  +    D  A   QR RD G P Y   RA   LS     ++
Sbjct: 441 MKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEE 500

Query: 453 INPALSRSNDTVLEATAALY----NQDLSWLELLPGGLLESHRDPGPLFSTIVLEQFVRL 508
           +N  L   +  + +    LY    N D+ W+  +   L+E  R  GPL + ++ +QF ++
Sbjct: 501 LNTVL--KSKMLAKKLLGLYGTPDNIDI-WIGAIAEPLVERGR-VGPLLACLLGKQFQQI 556

Query: 509 RDGDRYWFENTRNGLFSKKEIEEIR 533
           RDGDR+W+EN   G+F+ ++ + ++
Sbjct: 557 RDGDRFWWENP--GVFTNEQKDSLQ 579


>gi|40549418 lactoperoxidase isoform 1 preproprotein [Homo sapiens]
          Length = 712

 Score =  121 bits (304), Expect = 5e-27
 Identities = 148/565 (26%), Positives = 245/565 (43%), Gaps = 71/565 (12%)

Query: 14  GAWTPLGAQNPISWEVQRFDGWYNNLMEHRWGSKGSRLQRLVPASYADGVYQPLGEPH-- 71
           GA  P+   +P S   +   G  NN  +   G+    L R +PA Y DG+  P G     
Sbjct: 124 GAPAPVVRCDPCS-PYRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGK 182

Query: 72  ------LPNPRDLSNTISR--GPAGLASLRNRTVLGVFFGYHVLSDL-VSVETPGCPAEF 122
                 LP  R++SN I       G+   +NR++L + +G  V  DL  + +T    +E+
Sbjct: 183 TRNGFPLPLAREVSNKIVGYLNEEGVLD-QNRSLLFMQWGQIVDHDLDFAPDTELGSSEY 241

Query: 123 LN---------------IRIPPGDPMFDPDQRGDVVLPFQRSRWDPETGRSPSNPRDPAN 167
                            I  PP DP      +    +PF R+ +   T    S  R+  N
Sbjct: 242 SKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGK---CMPFFRAGFVCPTPPYKSLAREQIN 298

Query: 168 QVTGWLDGSAIYGSSHSWSDALRSFSR--GQLASGPD------PAFPRDSQNPLLMWAAP 219
            +T +LD S +Y S  S +  LR+ S   G +A   +      P  P DS+ P     +P
Sbjct: 299 ALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSKKP-----SP 353

Query: 220 DPATGQNGPRGLYAFGAERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHA 279
                       +  G  R +    L     L+ R HN  A+ L R +P W+ E+L+Q A
Sbjct: 354 CEFINTTARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEA 413

Query: 280 RKRVIATYQNIAVYEWLPSFL----QKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVP 335
           RK + A  Q I   ++LP  L    QK +P Y GY   +DP IS+ F  A  +F    VP
Sbjct: 414 RKILGAFVQIITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVFTFAF-RFGHLEVP 472

Query: 336 PGVYMRNASCHFQGVINRNSSVSRALRVCNSYWSREHPSLQSAEDVDALLLGMASQIAE- 394
             ++  + +    G       +       N++       +     +D L+ G+ ++ ++ 
Sbjct: 473 SSMFRLDENYQPWG---PEPELPLHTLFFNTW------RMVKDGGIDPLVRGLLAKKSKL 523

Query: 395 -REDHVLVEDVRDFWPGPL-KFSRTDHLASCLQRGRDLGLPSYTKARAALGLSPITRWQD 452
            +++ ++  ++R+    P  +    D  A   QR RD G P Y   RA   LS     ++
Sbjct: 524 MKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEE 583

Query: 453 INPALSRSNDTVLEATAALY----NQDLSWLELLPGGLLESHRDPGPLFSTIVLEQFVRL 508
           +N  L   +  + +    LY    N D+ W+  +   L+E  R  GPL + ++ +QF ++
Sbjct: 584 LNTVL--KSKMLAKKLLGLYGTPDNIDI-WIGAIAEPLVERGR-VGPLLACLLGKQFQQI 639

Query: 509 RDGDRYWFENTRNGLFSKKEIEEIR 533
           RDGDR+W+EN   G+F+ ++ + ++
Sbjct: 640 RDGDRFWWENP--GVFTNEQKDSLQ 662


>gi|28558984 thyroid peroxidase isoform b [Homo sapiens]
          Length = 876

 Score =  101 bits (251), Expect = 6e-21
 Identities = 141/559 (25%), Positives = 211/559 (37%), Gaps = 127/559 (22%)

Query: 34  GWYNNLMEHRWGSKGSRLQRLVPASYADGVYQPLGEPHLPNPRDLSNTISRGPAG----- 88
           G  NN    RWG+  + L R +P  Y DG  QP G     NP  L N     P       
Sbjct: 156 GACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGW----NPGFLYNGFPLPPVREVTRH 211

Query: 89  LASLRNRTV--------LGVFFGYHVLSDLVSVETPGCPAEF-----LNIRIPPGDPMFD 135
           +  + N  V        L + +G ++  D+         A F       +     +P F 
Sbjct: 212 VIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNPCFP 271

Query: 136 ---PDQR----GDVVLPFQRSRWDPETGR--------SPSNPRDPANQVTGWLDGSAIYG 180
              P++     G   LPF RS     TG         S +NPR   N +T +LD S +YG
Sbjct: 272 IQLPEEARPAAGTACLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDASTVYG 331

Query: 181 SSHSWSDALRSFSRGQLASGPDPAFPRDSQNPLLMWA--------APDPATGQNGPRGLY 232
           SS +    LR+++  +          RDS    L +         AP+P          +
Sbjct: 332 SSPALERQLRNWTSAEGLLRVHARL-RDSGRAYLPFVPPRAPAACAPEPGIPGETRGPCF 390

Query: 233 AFGAERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAV 292
             G  R +  P L AL  LW R HN  A  L   +  W  + ++Q ARK V A +Q I +
Sbjct: 391 LAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITL 450

Query: 293 YEWLPSFL-----QKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVPPGVYMRNASCHF 347
            +++P  L     Q+ +  Y GY    +P++S+ F  A+ +F    + P V  R     F
Sbjct: 451 RDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLV--RRLDASF 508

Query: 348 QGVINRNSSVSRALRVCNSYWSREHPSLQSAEDVDALLLGMASQIAEREDHVLVEDVRDF 407
           Q                      EHP                             D+   
Sbjct: 509 Q----------------------EHP-----------------------------DLPGL 517

Query: 408 WPGPLKFSRTDHLASCLQRGRDLGLPSYTKARAALGLSPITRWQDINPALSRSN--DTVL 465
           W     FS        L RG       Y + R   GL  +    D++ A++  +  D +L
Sbjct: 518 WLHQAFFSPWT-----LLRG------GYNEWREFCGLPRLETPADLSTAIASRSVADKIL 566

Query: 466 EATAALYNQDLSWLELLPGGLLES---HRDPGPLFSTIVLEQFVRLRDGDRYWFENTRNG 522
           +      N D+ WL    GGL E+       GPLF+ ++ +Q   LRDGD +W+EN+   
Sbjct: 567 DLYKHPDNIDV-WL----GGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSH-- 619

Query: 523 LFSKKEIEEIRNTTLQDVL 541
           +F+  +  E+   +L  V+
Sbjct: 620 VFTDAQRRELEKHSLSRVI 638


>gi|219842346 NADPH oxidase 4 isoform b [Homo sapiens]
          Length = 538

 Score = 92.8 bits (229), Expect = 2e-18
 Identities = 75/358 (20%), Positives = 142/358 (39%), Gaps = 76/358 (21%)

Query: 1208 FASHHFRRRSFRGFWLTHHLYILLYVLLIIHGSFALIQLPRFHIFFLVPAIIYGGDKLVS 1267
            + S HF      GF          +V + +         P+  ++   P  +Y  ++L  
Sbjct: 242  YFSEHFHEPFPEGFSKPAEFTQHKFVKICMEEPRFQANFPQTWLWISGPLCLYCAERLYR 301

Query: 1268 LSRKKVEISVVKAELLPSGVTHLRFQRPQGFEYKSGQWVRIACLALGTTEYHPFTLTSAP 1327
              R    ++++     PS V  +R  + + F+ + GQ++ + C ++   E HPFTLT  P
Sbjct: 302  YIRSNKPVTIISVISHPSDVMEIRMVK-ENFKARPGQYITLHCPSVSALENHPFTLTMCP 360

Query: 1328 HED--TLSLHIRAAGPWTTRLREIYSAPTGD--------RCARYPKLYLDGPFGEGHQEW 1377
             E   T  +H++  G WT R R++   P+          +   YPK            +W
Sbjct: 361  TETKATFGVHLKIVGDWTERFRDLLLPPSSQDSEILPFIQSRNYPK-----------DDW 409

Query: 1378 HKFEVSVLVGGGIGVTPFASILKDLVFKSSVSCQVFCKKIYFIWVTRTQRQFEWLADII- 1436
              +++                                +++YFIWV R  + F W AD++ 
Sbjct: 410  KPYKL--------------------------------RRLYFIWVCRDIQSFRWFADLLC 437

Query: 1437 ---REVEENDHQDLVSVHIYITQLAEKFDLRTTMLYICERHFQKVLNRSLFTGLRSITHF 1493
                +  + +  D V++ +Y++Q                   QK++    +  L S    
Sbjct: 438  MLHNKFWQENRPDYVNIQLYLSQ---------------TDGIQKIIGEK-YHALNSRLFI 481

Query: 1494 GRPPFEPFFNSLQEVHPQVRKIGVFSCGPPGMTKNVEKACQLINRQDRTHFSHHYENF 1551
            GRP ++  F+ + + + + + +GVF CGP  ++K + K     N    T F ++ E+F
Sbjct: 482  GRPRWKLLFDEIAK-YNRGKTVGVFCCGPNSLSKTLHKLSNQ-NNSYGTRFEYNKESF 537



 Score = 84.7 bits (208), Expect = 6e-16
 Identities = 58/206 (28%), Positives = 103/206 (50%), Gaps = 16/206 (7%)

Query: 1047 CVAVFYAIAGGLFLERAYYYAFAAHHTGITDTTRVGIILSRGTAASISFMFSYILLTMCR 1106
            C+ ++ ++   LF +    Y     +  +     +G+ LSR +A+ ++   S ILL MCR
Sbjct: 18   CLFIWLSMNVLLFWKTFLLYNQGPEYHYLHQMLGLGLCLSRASASVLNLNCSLILLPMCR 77

Query: 1107 NLITFLRETFLNRYVP-------FDAAVDFHRLIASTAIVLTVLHSVGHVVNVYLFSISP 1159
             L+ +LR +   + VP        D +  FH     T  + + +H   H+VN   FS++ 
Sbjct: 78   TLLAYLRGS---QKVPSRRTRRLLDKSRTFHITCGVTICIFSGVHVAAHLVNALNFSVNY 134

Query: 1160 LSVLSCLFPGLFHDDGSELPQKYYWWFFQTVPGLTGVVLLLILAIMYVFASHHFRRRSFR 1219
                  L    + D+    P+K     F TVPGLTGV ++++L +M   +++  R  ++ 
Sbjct: 135  SEDFVELNAARYRDED---PRKL---LFTTVPGLTGVCMVVVLFLMITASTYAIRVSNYD 188

Query: 1220 GFWLTHHLYILLYVLLIIHGSFALIQ 1245
             FW TH+L+ + Y+LL +H S  L++
Sbjct: 189  IFWYTHNLFFVFYMLLTLHVSGGLLK 214


>gi|40254415 guanylate cyclase activator 1A (retina) [Homo sapiens]
          Length = 201

 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 41/125 (32%), Positives = 67/125 (53%), Gaps = 6/125 (4%)

Query: 801 ELSRAEFAESLGLK----PQDMFVESMFSLADKDGNGYLSFREFLDILVVFMKGSPEEKS 856
           +L+  EF +  GLK        +VE MF   D + +GY+ F E++  L + +KG  E+K 
Sbjct: 33  QLTLYEFRQFFGLKNLSPSASQYVEQMFETFDFNKDGYIDFMEYVAALSLVLKGKVEQKL 92

Query: 857 RLMFRMYDFDGNGLISKDEFIRMLRSFIEISNNCLSKAQLA-EVVESMFRESGFQDKEEL 915
           R  F++YD DGNG I +DE + ++++ I   N C      A E  +++F +       EL
Sbjct: 93  RWYFKLYDVDGNGCIDRDELLTIIQA-IRAINPCSDTTMTAEEFTDTVFSKIDVNGDGEL 151

Query: 916 TWEDF 920
           + E+F
Sbjct: 152 SLEEF 156


>gi|28558990 thyroid peroxidase isoform e [Homo sapiens]
          Length = 760

 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 69/252 (27%), Positives = 121/252 (48%), Gaps = 23/252 (9%)

Query: 297 PSFLQKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVPPGVYMRNASCHFQGVINRNSS 356
           P   Q+ +  Y GY    +P++S+ F  A+ +F    + P V   +AS  FQ        
Sbjct: 287 PEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDAS--FQ-----EHP 339

Query: 357 VSRALRVCNSYWSREHPSLQSAEDVDALLLGMASQIAERE--DHVLVEDVRDFWPGPLKF 414
               L +  +++S    +L     +D L+ G+ ++ A+ +  D ++ E++ +        
Sbjct: 340 DLPGLWLHQAFFSPW--TLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLSNS 397

Query: 415 SRTDHLASCLQRGRDLGLPSYTKARAALGLSPITRWQDINPALSRSN--DTVLEATAALY 472
           S  D  +  LQRGRD GLP Y + R   GL  +    D++ A++  +  D +L+      
Sbjct: 398 STLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDLYKHPD 457

Query: 473 NQDLSWLELLPGGLLES---HRDPGPLFSTIVLEQFVRLRDGDRYWFENTRNGLFSKKEI 529
           N D+ WL    GGL E+       GPLF+ ++ +Q   LRDGD +W+EN+   +F+  + 
Sbjct: 458 NIDV-WL----GGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSH--VFTDAQR 510

Query: 530 EEIRNTTLQDVL 541
            E+   +L  V+
Sbjct: 511 RELEKHSLSRVI 522



 Score = 32.0 bits (71), Expect = 4.8
 Identities = 15/35 (42%), Positives = 18/35 (51%)

Query: 34  GWYNNLMEHRWGSKGSRLQRLVPASYADGVYQPLG 68
           G  NN    RWG+  + L R +P  Y DG  QP G
Sbjct: 156 GACNNRDHPRWGASNTALARWLPPVYEDGFSQPRG 190


>gi|4506025 protein phosphatase 3, regulatory subunit B, alpha
           isoform 1 [Homo sapiens]
          Length = 170

 Score = 62.0 bits (149), Expect = 4e-09
 Identities = 39/120 (32%), Positives = 64/120 (53%), Gaps = 5/120 (4%)

Query: 802 LSRAEFAESLGLKPQDMFVESMFSLADKDGNGYLSFREFLDILVVF-MKGSPEEKSRLMF 860
           LS  EF  SL    Q+  V+ +  + D DGNG + F+EF++ +  F +KG  E+K R  F
Sbjct: 38  LSVEEFM-SLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAF 96

Query: 861 RMYDFDGNGLISKDEFIRMLRSFIEISNNCLSKAQLAEVVESMFRESGFQDKEELTWEDF 920
           R+YD D +G IS  E  ++L+  +    N L   QL ++V+     +       +++E+F
Sbjct: 97  RIYDMDKDGYISNGELFQVLKMMV---GNNLKDTQLQQIVDKTIINADKDGDGRISFEEF 153


>gi|98985795 neurocalcin delta [Homo sapiens]
          Length = 193

 Score = 61.6 bits (148), Expect = 6e-09
 Identities = 39/135 (28%), Positives = 69/135 (51%), Gaps = 8/135 (5%)

Query: 794 VREALTCELSRAEFAESLG----LKPQDMFVESMFSLADKDGNGYLSFREFLDILVVFMK 849
           +R+  +  LS  EF +  G          F E +F   D +G+G + FREF+  L V  +
Sbjct: 35  LRDCPSGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSR 94

Query: 850 GSPEEKSRLMFRMYDFDGNGLISKDEFIRMLRSFIEISNNCL----SKAQLAEVVESMFR 905
           G  E+K +  F MYD DGNG ISK E + ++++  ++ ++ +     ++   +  E +FR
Sbjct: 95  GKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFR 154

Query: 906 ESGFQDKEELTWEDF 920
           +       +L+ E+F
Sbjct: 155 QMDTNRDGKLSLEEF 169



 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 12/71 (16%)

Query: 824 FSLADKDGNGYLSFREFLDILVVFMK------------GSPEEKSRLMFRMYDFDGNGLI 871
           FS+ D DGNGY+S  E L+I+    K             +PE+++  +FR  D + +G +
Sbjct: 105 FSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKL 164

Query: 872 SKDEFIRMLRS 882
           S +EFIR  +S
Sbjct: 165 SLEEFIRGAKS 175


>gi|98985793 neurocalcin delta [Homo sapiens]
          Length = 193

 Score = 61.6 bits (148), Expect = 6e-09
 Identities = 39/135 (28%), Positives = 69/135 (51%), Gaps = 8/135 (5%)

Query: 794 VREALTCELSRAEFAESLG----LKPQDMFVESMFSLADKDGNGYLSFREFLDILVVFMK 849
           +R+  +  LS  EF +  G          F E +F   D +G+G + FREF+  L V  +
Sbjct: 35  LRDCPSGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSR 94

Query: 850 GSPEEKSRLMFRMYDFDGNGLISKDEFIRMLRSFIEISNNCL----SKAQLAEVVESMFR 905
           G  E+K +  F MYD DGNG ISK E + ++++  ++ ++ +     ++   +  E +FR
Sbjct: 95  GKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFR 154

Query: 906 ESGFQDKEELTWEDF 920
           +       +L+ E+F
Sbjct: 155 QMDTNRDGKLSLEEF 169



 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 12/71 (16%)

Query: 824 FSLADKDGNGYLSFREFLDILVVFMK------------GSPEEKSRLMFRMYDFDGNGLI 871
           FS+ D DGNGY+S  E L+I+    K             +PE+++  +FR  D + +G +
Sbjct: 105 FSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKL 164

Query: 872 SKDEFIRMLRS 882
           S +EFIR  +S
Sbjct: 165 SLEEFIRGAKS 175


>gi|98985791 neurocalcin delta [Homo sapiens]
          Length = 193

 Score = 61.6 bits (148), Expect = 6e-09
 Identities = 39/135 (28%), Positives = 69/135 (51%), Gaps = 8/135 (5%)

Query: 794 VREALTCELSRAEFAESLG----LKPQDMFVESMFSLADKDGNGYLSFREFLDILVVFMK 849
           +R+  +  LS  EF +  G          F E +F   D +G+G + FREF+  L V  +
Sbjct: 35  LRDCPSGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSR 94

Query: 850 GSPEEKSRLMFRMYDFDGNGLISKDEFIRMLRSFIEISNNCL----SKAQLAEVVESMFR 905
           G  E+K +  F MYD DGNG ISK E + ++++  ++ ++ +     ++   +  E +FR
Sbjct: 95  GKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFR 154

Query: 906 ESGFQDKEELTWEDF 920
           +       +L+ E+F
Sbjct: 155 QMDTNRDGKLSLEEF 169



 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 12/71 (16%)

Query: 824 FSLADKDGNGYLSFREFLDILVVFMK------------GSPEEKSRLMFRMYDFDGNGLI 871
           FS+ D DGNGY+S  E L+I+    K             +PE+++  +FR  D + +G +
Sbjct: 105 FSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKL 164

Query: 872 SKDEFIRMLRS 882
           S +EFIR  +S
Sbjct: 165 SLEEFIRGAKS 175


>gi|98985789 neurocalcin delta [Homo sapiens]
          Length = 193

 Score = 61.6 bits (148), Expect = 6e-09
 Identities = 39/135 (28%), Positives = 69/135 (51%), Gaps = 8/135 (5%)

Query: 794 VREALTCELSRAEFAESLG----LKPQDMFVESMFSLADKDGNGYLSFREFLDILVVFMK 849
           +R+  +  LS  EF +  G          F E +F   D +G+G + FREF+  L V  +
Sbjct: 35  LRDCPSGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSR 94

Query: 850 GSPEEKSRLMFRMYDFDGNGLISKDEFIRMLRSFIEISNNCL----SKAQLAEVVESMFR 905
           G  E+K +  F MYD DGNG ISK E + ++++  ++ ++ +     ++   +  E +FR
Sbjct: 95  GKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFR 154

Query: 906 ESGFQDKEELTWEDF 920
           +       +L+ E+F
Sbjct: 155 QMDTNRDGKLSLEEF 169



 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 12/71 (16%)

Query: 824 FSLADKDGNGYLSFREFLDILVVFMK------------GSPEEKSRLMFRMYDFDGNGLI 871
           FS+ D DGNGY+S  E L+I+    K             +PE+++  +FR  D + +G +
Sbjct: 105 FSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKL 164

Query: 872 SKDEFIRMLRS 882
           S +EFIR  +S
Sbjct: 165 SLEEFIRGAKS 175


>gi|98985787 neurocalcin delta [Homo sapiens]
          Length = 193

 Score = 61.6 bits (148), Expect = 6e-09
 Identities = 39/135 (28%), Positives = 69/135 (51%), Gaps = 8/135 (5%)

Query: 794 VREALTCELSRAEFAESLG----LKPQDMFVESMFSLADKDGNGYLSFREFLDILVVFMK 849
           +R+  +  LS  EF +  G          F E +F   D +G+G + FREF+  L V  +
Sbjct: 35  LRDCPSGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSR 94

Query: 850 GSPEEKSRLMFRMYDFDGNGLISKDEFIRMLRSFIEISNNCL----SKAQLAEVVESMFR 905
           G  E+K +  F MYD DGNG ISK E + ++++  ++ ++ +     ++   +  E +FR
Sbjct: 95  GKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFR 154

Query: 906 ESGFQDKEELTWEDF 920
           +       +L+ E+F
Sbjct: 155 QMDTNRDGKLSLEEF 169



 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 12/71 (16%)

Query: 824 FSLADKDGNGYLSFREFLDILVVFMK------------GSPEEKSRLMFRMYDFDGNGLI 871
           FS+ D DGNGY+S  E L+I+    K             +PE+++  +FR  D + +G +
Sbjct: 105 FSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKL 164

Query: 872 SKDEFIRMLRS 882
           S +EFIR  +S
Sbjct: 165 SLEEFIRGAKS 175


>gi|98985785 neurocalcin delta [Homo sapiens]
          Length = 193

 Score = 61.6 bits (148), Expect = 6e-09
 Identities = 39/135 (28%), Positives = 69/135 (51%), Gaps = 8/135 (5%)

Query: 794 VREALTCELSRAEFAESLG----LKPQDMFVESMFSLADKDGNGYLSFREFLDILVVFMK 849
           +R+  +  LS  EF +  G          F E +F   D +G+G + FREF+  L V  +
Sbjct: 35  LRDCPSGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSR 94

Query: 850 GSPEEKSRLMFRMYDFDGNGLISKDEFIRMLRSFIEISNNCL----SKAQLAEVVESMFR 905
           G  E+K +  F MYD DGNG ISK E + ++++  ++ ++ +     ++   +  E +FR
Sbjct: 95  GKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFR 154

Query: 906 ESGFQDKEELTWEDF 920
           +       +L+ E+F
Sbjct: 155 QMDTNRDGKLSLEEF 169



 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 12/71 (16%)

Query: 824 FSLADKDGNGYLSFREFLDILVVFMK------------GSPEEKSRLMFRMYDFDGNGLI 871
           FS+ D DGNGY+S  E L+I+    K             +PE+++  +FR  D + +G +
Sbjct: 105 FSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKL 164

Query: 872 SKDEFIRMLRS 882
           S +EFIR  +S
Sbjct: 165 SLEEFIRGAKS 175


>gi|98985783 neurocalcin delta [Homo sapiens]
          Length = 193

 Score = 61.6 bits (148), Expect = 6e-09
 Identities = 39/135 (28%), Positives = 69/135 (51%), Gaps = 8/135 (5%)

Query: 794 VREALTCELSRAEFAESLG----LKPQDMFVESMFSLADKDGNGYLSFREFLDILVVFMK 849
           +R+  +  LS  EF +  G          F E +F   D +G+G + FREF+  L V  +
Sbjct: 35  LRDCPSGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSR 94

Query: 850 GSPEEKSRLMFRMYDFDGNGLISKDEFIRMLRSFIEISNNCL----SKAQLAEVVESMFR 905
           G  E+K +  F MYD DGNG ISK E + ++++  ++ ++ +     ++   +  E +FR
Sbjct: 95  GKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFR 154

Query: 906 ESGFQDKEELTWEDF 920
           +       +L+ E+F
Sbjct: 155 QMDTNRDGKLSLEEF 169



 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 12/71 (16%)

Query: 824 FSLADKDGNGYLSFREFLDILVVFMK------------GSPEEKSRLMFRMYDFDGNGLI 871
           FS+ D DGNGY+S  E L+I+    K             +PE+++  +FR  D + +G +
Sbjct: 105 FSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKL 164

Query: 872 SKDEFIRMLRS 882
           S +EFIR  +S
Sbjct: 165 SLEEFIRGAKS 175


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.139    0.435 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,780,760
Number of Sequences: 37866
Number of extensions: 3039933
Number of successful extensions: 9787
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 100
Number of HSP's successfully gapped in prelim test: 60
Number of HSP's that attempted gapping in prelim test: 9292
Number of HSP's gapped (non-prelim): 362
length of query: 1551
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1435
effective length of database: 13,855,062
effective search space: 19882013970
effective search space used: 19882013970
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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