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Search of human proteins with 28558988
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|28558988 thyroid peroxidase isoform d [Homo sapiens]
(889 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|28558988 thyroid peroxidase isoform d [Homo sapiens] 1833 0.0
gi|28558982 thyroid peroxidase isoform a [Homo sapiens] 1811 0.0
gi|28558984 thyroid peroxidase isoform b [Homo sapiens] 1671 0.0
gi|28558990 thyroid peroxidase isoform e [Homo sapiens] 904 0.0
gi|4557759 myeloperoxidase [Homo sapiens] 606 e-173
gi|4503595 eosinophil peroxidase [Homo sapiens] 596 e-170
gi|40549418 lactoperoxidase isoform 1 preproprotein [Homo sapiens] 540 e-153
gi|109150416 peroxidasin [Homo sapiens] 539 e-153
gi|231569458 lactoperoxidase isoform 3 preproprotein [Homo sapiens] 533 e-151
gi|126517478 peroxidasin homolog-like [Homo sapiens] 474 e-133
gi|20149640 dual oxidase 1 precursor [Homo sapiens] 130 4e-30
gi|28872751 dual oxidase 1 precursor [Homo sapiens] 130 4e-30
gi|132566532 dual oxidase 2 precursor [Homo sapiens] 120 7e-27
gi|4506265 prostaglandin-endoperoxide synthase 2 precursor [Homo... 57 1e-07
gi|18104969 prostaglandin-endoperoxide synthase 1 isoform 2 prec... 50 9e-06
gi|18104967 prostaglandin-endoperoxide synthase 1 isoform 1 prec... 50 9e-06
gi|148886654 polydom [Homo sapiens] 47 8e-05
gi|5031695 H factor (complement)-like 3 [Homo sapiens] 44 9e-04
gi|62739186 complement factor H isoform a precursor [Homo sapiens] 42 0.002
gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens] 42 0.002
gi|32261332 seizure related 6 homolog (mouse)-like precursor [Ho... 42 0.002
gi|118442839 complement factor H-related 1 [Homo sapiens] 42 0.003
gi|4502503 complement component 4 binding protein, alpha chain p... 42 0.003
gi|239758113 PREDICTED: similar to complement factor H-related 1... 42 0.003
gi|117320518 complement factor H-related 4 [Homo sapiens] 40 0.010
gi|168693643 decay accelerating factor for complement isoform 2 ... 40 0.013
gi|10835143 decay accelerating factor for complement isoform 1 p... 40 0.013
gi|166235140 seizure related 6 homolog (mouse)-like 2 isoform 4 ... 39 0.016
gi|166235138 seizure related 6 homolog (mouse)-like 2 isoform 3 ... 39 0.016
gi|166235136 seizure related 6 homolog (mouse)-like 2 isoform 2 ... 39 0.016
>gi|28558988 thyroid peroxidase isoform d [Homo sapiens]
Length = 889
Score = 1833 bits (4747), Expect = 0.0
Identities = 889/889 (100%), Positives = 889/889 (100%)
Query: 1 MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR 60
MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR
Sbjct: 1 MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR 60
Query: 61 NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS 120
NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS
Sbjct: 61 NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS 120
Query: 121 EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV 180
EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV
Sbjct: 121 EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV 180
Query: 181 YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD 240
YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD
Sbjct: 181 YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD 240
Query: 241 IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQLPEEARPAAGTACLPFYRSSAACGTGD 300
IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQLPEEARPAAGTACLPFYRSSAACGTGD
Sbjct: 241 IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQLPEEARPAAGTACLPFYRSSAACGTGD 300
Query: 301 QGALFGNLSTANPRQQMNGLTSFLDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSG 360
QGALFGNLSTANPRQQMNGLTSFLDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSG
Sbjct: 301 QGALFGNLSTANPRQQMNGLTSFLDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSG 360
Query: 361 RAYLPFVPPRAPAACAPEPGIPGETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAA 420
RAYLPFVPPRAPAACAPEPGIPGETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAA
Sbjct: 361 RAYLPFVPPRAPAACAPEPGIPGETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAA 420
Query: 421 LKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPT 480
LKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPT
Sbjct: 421 LKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPT 480
Query: 481 VSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIR 540
VSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIR
Sbjct: 481 VSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIR 540
Query: 541 GLLARPAKLQVQDQLMNEELTERLFVLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGL 600
GLLARPAKLQVQDQLMNEELTERLFVLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGL
Sbjct: 541 GLLARPAKLQVQDQLMNEELTERLFVLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGL 600
Query: 601 PRLETPADLSTAIASRSVADKILDLYKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQ 660
PRLETPADLSTAIASRSVADKILDLYKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQ
Sbjct: 601 PRLETPADLSTAIASRSVADKILDLYKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQ 660
Query: 661 MKALRDGDWFWWENSHVFTDAQRRELEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFES 720
MKALRDGDWFWWENSHVFTDAQRRELEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFES
Sbjct: 661 MKALRDGDWFWWENSHVFTDAQRRELEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFES 720
Query: 721 CDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQL 780
CDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQL
Sbjct: 721 CDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQL 780
Query: 781 TCTQEGWDFQPPLCKDSGRLPRVTWISMSLAALLIGGFAGLTSTVICRWTRTGTKSTLPI 840
TCTQEGWDFQPPLCKDSGRLPRVTWISMSLAALLIGGFAGLTSTVICRWTRTGTKSTLPI
Sbjct: 781 TCTQEGWDFQPPLCKDSGRLPRVTWISMSLAALLIGGFAGLTSTVICRWTRTGTKSTLPI 840
Query: 841 SETGGGTPELRCGKHQAVGTSPQRAAAQDSEQESAGMEGRDTHRLPRAL 889
SETGGGTPELRCGKHQAVGTSPQRAAAQDSEQESAGMEGRDTHRLPRAL
Sbjct: 841 SETGGGTPELRCGKHQAVGTSPQRAAAQDSEQESAGMEGRDTHRLPRAL 889
>gi|28558982 thyroid peroxidase isoform a [Homo sapiens]
Length = 933
Score = 1811 bits (4692), Expect = 0.0
Identities = 889/933 (95%), Positives = 889/933 (95%), Gaps = 44/933 (4%)
Query: 1 MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR 60
MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR
Sbjct: 1 MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR 60
Query: 61 NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS 120
NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS
Sbjct: 61 NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS 120
Query: 121 EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV 180
EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV
Sbjct: 121 EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV 180
Query: 181 YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD 240
YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD
Sbjct: 181 YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD 240
Query: 241 IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQLPEEARPAAGTACLPFYRSSAACGTGD 300
IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQLPEEARPAAGTACLPFYRSSAACGTGD
Sbjct: 241 IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQLPEEARPAAGTACLPFYRSSAACGTGD 300
Query: 301 QGALFGNLSTANPRQQMNGLTSFLDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSG 360
QGALFGNLSTANPRQQMNGLTSFLDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSG
Sbjct: 301 QGALFGNLSTANPRQQMNGLTSFLDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSG 360
Query: 361 RAYLPFVPPRAPAACAPEPGIPGETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAA 420
RAYLPFVPPRAPAACAPEPGIPGETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAA
Sbjct: 361 RAYLPFVPPRAPAACAPEPGIPGETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAA 420
Query: 421 LKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPT 480
LKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPT
Sbjct: 421 LKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPT 480
Query: 481 VSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIR 540
VSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIR
Sbjct: 481 VSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIR 540
Query: 541 GLLARPAKLQVQDQLMNEELTERLFVLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGL 600
GLLARPAKLQVQDQLMNEELTERLFVLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGL
Sbjct: 541 GLLARPAKLQVQDQLMNEELTERLFVLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGL 600
Query: 601 PRLETPADLSTAIASRSVADKILDLYKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQ 660
PRLETPADLSTAIASRSVADKILDLYKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQ
Sbjct: 601 PRLETPADLSTAIASRSVADKILDLYKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQ 660
Query: 661 MKALRDGDWFWWENSHVFTDAQRRELEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFES 720
MKALRDGDWFWWENSHVFTDAQRRELEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFES
Sbjct: 661 MKALRDGDWFWWENSHVFTDAQRRELEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFES 720
Query: 721 CDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQL 780
CDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQL
Sbjct: 721 CDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQL 780
Query: 781 TCTQEGWDFQPPLCK--------------------------------------------D 796
TCTQEGWDFQPPLCK D
Sbjct: 781 TCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 840
Query: 797 SGRLPRVTWISMSLAALLIGGFAGLTSTVICRWTRTGTKSTLPISETGGGTPELRCGKHQ 856
SGRLPRVTWISMSLAALLIGGFAGLTSTVICRWTRTGTKSTLPISETGGGTPELRCGKHQ
Sbjct: 841 SGRLPRVTWISMSLAALLIGGFAGLTSTVICRWTRTGTKSTLPISETGGGTPELRCGKHQ 900
Query: 857 AVGTSPQRAAAQDSEQESAGMEGRDTHRLPRAL 889
AVGTSPQRAAAQDSEQESAGMEGRDTHRLPRAL
Sbjct: 901 AVGTSPQRAAAQDSEQESAGMEGRDTHRLPRAL 933
>gi|28558984 thyroid peroxidase isoform b [Homo sapiens]
Length = 876
Score = 1671 bits (4328), Expect = 0.0
Identities = 831/933 (89%), Positives = 832/933 (89%), Gaps = 101/933 (10%)
Query: 1 MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR 60
MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR
Sbjct: 1 MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR 60
Query: 61 NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS 120
NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS
Sbjct: 61 NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS 120
Query: 121 EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV 180
EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV
Sbjct: 121 EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV 180
Query: 181 YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD 240
YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD
Sbjct: 181 YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD 240
Query: 241 IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQLPEEARPAAGTACLPFYRSSAACGTGD 300
IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQLPEEARPAAGTACLPFYRSSAACGTGD
Sbjct: 241 IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQLPEEARPAAGTACLPFYRSSAACGTGD 300
Query: 301 QGALFGNLSTANPRQQMNGLTSFLDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSG 360
QGALFGNLSTANPRQQMNGLTSFLDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSG
Sbjct: 301 QGALFGNLSTANPRQQMNGLTSFLDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSG 360
Query: 361 RAYLPFVPPRAPAACAPEPGIPGETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAA 420
RAYLPFVPPRAPAACAPEPGIPGETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAA
Sbjct: 361 RAYLPFVPPRAPAACAPEPGIPGETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAA 420
Query: 421 LKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPT 480
LKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPT
Sbjct: 421 LKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPT 480
Query: 481 VSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIR 540
VSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLPGLWLHQAFFSPWT L+R
Sbjct: 481 VSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLPGLWLHQAFFSPWT---------LLR 531
Query: 541 GLLARPAKLQVQDQLMNEELTERLFVLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGL 600
G GYNEWREFCGL
Sbjct: 532 G------------------------------------------------GYNEWREFCGL 543
Query: 601 PRLETPADLSTAIASRSVADKILDLYKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQ 660
PRLETPADLSTAIASRSVADKILDLYKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQ
Sbjct: 544 PRLETPADLSTAIASRSVADKILDLYKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQ 603
Query: 661 MKALRDGDWFWWENSHVFTDAQRRELEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFES 720
MKALRDGDWFWWENSHVFTDAQRRELEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFES
Sbjct: 604 MKALRDGDWFWWENSHVFTDAQRRELEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFES 663
Query: 721 CDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQL 780
CDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQL
Sbjct: 664 CDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQL 723
Query: 781 TCTQEGWDFQPPLCK--------------------------------------------D 796
TCTQEGWDFQPPLCK D
Sbjct: 724 TCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
Query: 797 SGRLPRVTWISMSLAALLIGGFAGLTSTVICRWTRTGTKSTLPISETGGGTPELRCGKHQ 856
SGRLPRVTWISMSLAALLIGGFAGLTSTVICRWTRTGTKSTLPISETGGGTPELRCGKHQ
Sbjct: 784 SGRLPRVTWISMSLAALLIGGFAGLTSTVICRWTRTGTKSTLPISETGGGTPELRCGKHQ 843
Query: 857 AVGTSPQRAAAQDSEQESAGMEGRDTHRLPRAL 889
AVGTSPQRAAAQDSEQESAGMEGRDTHRLPRAL
Sbjct: 844 AVGTSPQRAAAQDSEQESAGMEGRDTHRLPRAL 876
>gi|28558990 thyroid peroxidase isoform e [Homo sapiens]
Length = 760
Score = 904 bits (2335), Expect = 0.0
Identities = 444/488 (90%), Positives = 444/488 (90%), Gaps = 44/488 (9%)
Query: 446 QIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLD 505
QIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLD
Sbjct: 273 QIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLD 332
Query: 506 ASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLF 565
ASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLF
Sbjct: 333 ASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLF 392
Query: 566 VLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDL 625
VLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDL
Sbjct: 393 VLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDL 452
Query: 626 YKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRE 685
YKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRE
Sbjct: 453 YKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRE 512
Query: 686 LEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRETFPQDDKCGFP 745
LEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRETFPQDDKCGFP
Sbjct: 513 LEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRETFPQDDKCGFP 572
Query: 746 ESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCK---------- 795
ESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCK
Sbjct: 573 ESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDVNECADGAH 632
Query: 796 ----------------------------------DSGRLPRVTWISMSLAALLIGGFAGL 821
DSGRLPRVTWISMSLAALLIGGFAGL
Sbjct: 633 PPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPRVTWISMSLAALLIGGFAGL 692
Query: 822 TSTVICRWTRTGTKSTLPISETGGGTPELRCGKHQAVGTSPQRAAAQDSEQESAGMEGRD 881
TSTVICRWTRTGTKSTLPISETGGGTPELRCGKHQAVGTSPQRAAAQDSEQESAGMEGRD
Sbjct: 693 TSTVICRWTRTGTKSTLPISETGGGTPELRCGKHQAVGTSPQRAAAQDSEQESAGMEGRD 752
Query: 882 THRLPRAL 889
THRLPRAL
Sbjct: 753 THRLPRAL 760
Score = 564 bits (1453), Expect = e-160
Identities = 273/274 (99%), Positives = 274/274 (100%)
Query: 1 MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR 60
MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR
Sbjct: 1 MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR 60
Query: 61 NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS 120
NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS
Sbjct: 61 NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS 120
Query: 121 EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV 180
EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV
Sbjct: 121 EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV 180
Query: 181 YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD 240
YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD
Sbjct: 181 YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD 240
Query: 241 IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQL 274
IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQ+
Sbjct: 241 IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQI 274
>gi|4557759 myeloperoxidase [Homo sapiens]
Length = 745
Score = 606 bits (1562), Expect = e-173
Identities = 313/708 (44%), Positives = 437/708 (61%), Gaps = 24/708 (3%)
Query: 32 GKPEESRVSSVLEESKRLVDTAMYATMQRNLKKR---GILSPAQLLSFSKLPEPTSGVIA 88
G+ + S V S +EE+K+LVD A Y + ++K+R G SP +LLS+ K P +
Sbjct: 55 GEVDTSLVLSSMEEAKQLVDKA-YKERRESIKQRLRSGSASPMELLSYFKQPVAATRTAV 113
Query: 89 RAAEIMETSIQAMKRKVNLKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLA 148
RAA+ + ++ ++RK+ ++ + TD L+ L++++ SGC + CP
Sbjct: 114 RAADYLHVALDLLERKLRSLWRRPFNVTDVLTPAQLNVLSKSSGCAYQDVGVTCPEQ--- 170
Query: 149 NKYRPITGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREV 208
+KYR ITG CNNR P GASN A RWLP YEDGFS P GW PG NGFP+ R V
Sbjct: 171 DKYRTITGMCNNRRSPTLGASNRAFVRWLPAEYEDGFSLPYGWTPGVKRNGFPVALARAV 230
Query: 209 TRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNP 268
+ +++ + +T D S + M WGQ +DHD+ FTP+ ++A+F G +C+ +C Q P
Sbjct: 231 SNEIVRFPTDQLTPDQERSLMFMQWGQLLDHDLDFTPEPAARASFVTGVNCETSCVQQPP 290
Query: 269 CFPIQLP-EEARPAAGTACLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDAS 327
CFP+++P + R C+PF+RS AC S R Q+N LTSF+DAS
Sbjct: 291 CFPLKIPPNDPRIKNQADCIPFFRSCPACPG----------SNITIRNQINALTSFVDAS 340
Query: 328 TVYGSSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPGETRG 387
VYGS L R LRN ++ GLL V+ R +D+GRA LPF R
Sbjct: 341 MVYGSEEPLARNLRNMSNQLGLLAVNQRFQDNGRALLPFDNLHDDPCLLTNRS----ARI 396
Query: 388 PCFLAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQI 447
PCFLAGD R+SE+P LT++HTL LREHNRLA LK+LN W + +YQEARK+VGA+ QI
Sbjct: 397 PCFLAGDTRSSEMPELTSMHTLLLREHNRLATELKSLNPRWDGERLYQEARKIVGAMVQI 456
Query: 448 ITLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDAS 507
IT RDY+P +LGP A ++Y+ Y Y+ + +P ++NVF T AFR+GH I P + RLD
Sbjct: 457 ITYRDYLPLVLGPTAMRKYLPTYRSYNDSVDPRIANVF-TNAFRYGHTLIQPFMFRLDNR 515
Query: 508 FQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVL 567
+Q P + L + FF+ W ++ GG+DP++RGL+A PAKL Q+Q+ +E+ ERLF
Sbjct: 516 YQPMEPNPRVPLSRVFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQ 575
Query: 568 SNSSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDLYK 627
LDL ++N+QR RDHGLPGYN WR FCGLP+ ET L T + + +A K+++ Y
Sbjct: 576 VMRIGLDLPALNMQRSRDHGLPGYNAWRRFCGLPQPETVGQLGTVLRNLKLARKLMEQYG 635
Query: 628 HPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRELE 687
P+NID+W+GG++E + R GPL AC+IG Q + LRDGD FWWEN VF+ QR+ L
Sbjct: 636 TPNNIDIWMGGVSEPLKRKGRVGPLLACIIGTQFRKLRDGDRFWWENEGVFSMQQRQALA 695
Query: 688 KHSLSRVICDNTGLTRVPM-DAFQVGKFPEDFESCDSITGMNLEAWRE 734
+ SL R+ICDNTG+T V + F +P DF +C ++ +NL +WRE
Sbjct: 696 QISLPRIICDNTGITTVSKNNIFMSNSYPRDFVNCSTLPALNLASWRE 743
>gi|4503595 eosinophil peroxidase [Homo sapiens]
Length = 715
Score = 596 bits (1537), Expect = e-170
Identities = 314/708 (44%), Positives = 428/708 (60%), Gaps = 25/708 (3%)
Query: 32 GKPEESRVSSVLEESKRLVDTAMYATMQRNLKKR---GILSPAQLLSFSKLPEPTSGVIA 88
G E S + + E+K LVD A Y Q+++K+R G SP LLS+ K P + +
Sbjct: 29 GAVETSVLRDCIAEAKLLVDAA-YNWTQKSIKQRLRSGSASPMDLLSYFKQPVAATRTVV 87
Query: 89 RAAEIMETSIQAMKRKVNLKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLA 148
RAA+ M ++ ++ K+ + + TD L+E L +++ SGC +C +
Sbjct: 88 RAADYMHVALGLLEEKLQPQRSGPFNVTDVLTEPQLRLLSQASGCALRDQAERC-----S 142
Query: 149 NKYRPITGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREV 208
+KYR ITG CNN+ P GASN ALARWLP YEDG S P GW P NGF LP VR V
Sbjct: 143 DKYRTITGRCNNKRRPLLGASNQALARWLPAEYEDGLSLPFGWTPSRRRNGFLLPLVRAV 202
Query: 209 TRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNP 268
+ +++ NE +T D + + M WGQ+IDHD+ F+P+S ++ AF G DC+ TC P
Sbjct: 203 SNQIVRFPNERLTSDRGRALMFMQWGQFIDHDLDFSPESPARVAFTAGVDCERTCAQLPP 262
Query: 269 CFPIQLP-EEARPAAGTACLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDAS 327
CFPI++P + R C+PF+RS+ +C R Q+N LTSF+DAS
Sbjct: 263 CFPIKIPPNDPRIKNQRDCIPFFRSAPSCPQNKNRV----------RNQINALTSFVDAS 312
Query: 328 TVYGSSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPGETRG 387
VYGS +L +LRN T+ GLL ++ R +D+GRA LPF R
Sbjct: 313 MVYGSEVSLSLRLRNRTNYLGLLAINQRFQDNGRALLPFDNLHDDPCLLTNRS----ARI 368
Query: 388 PCFLAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQI 447
PCFLAGD R++E P L A+HTL++REHNRLA L+ LN W+ D +Y EARK++GA+ QI
Sbjct: 369 PCFLAGDTRSTETPKLAAMHTLFMREHNRLATELRRLNPRWNGDKLYNEARKIMGAMVQI 428
Query: 448 ITLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDAS 507
IT RD++P +LG ++ +G Y GY S +P V+NVF T AFRFGH + P + RLD+
Sbjct: 429 ITYRDFLPLVLGKARARRTLGHYRGYCSNVDPRVANVF-TLAFRFGHTMLQPFMFRLDSQ 487
Query: 508 FQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVL 567
++ + L AFF+ W ++ GG+DP++RGL+A PAKL QD ++ +EL +RLF
Sbjct: 488 YRASAPNSHVPLSSAFFASWRIVYEGGIDPILRGLMATPAKLNRQDAMLVDELRDRLFRQ 547
Query: 568 SNSSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDLYK 627
LDLA++N+QR RDHGLPGYN WR FCGL + A LS + ++ +A K L+LY
Sbjct: 548 VRRIGLDLAALNMQRSRDHGLPGYNAWRRFCGLSQPRNLAQLSRVLKNQDLARKFLNLYG 607
Query: 628 HPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRELE 687
PDNID+W+G +AE LP AR GPL ACL Q + RDGD FWW+ VFT QR+ L
Sbjct: 608 TPDNIDIWIGAIAEPLLPGARVGPLLACLFENQFRRARDGDRFWWQKRGVFTKRQRKALS 667
Query: 688 KHSLSRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRET 735
+ SLSR+ICDNTG+T V D F+ +P F +C I +NL AWR T
Sbjct: 668 RISLSRIICDNTGITTVSRDIFRANIYPRGFVNCSRIPRLNLSAWRGT 715
>gi|40549418 lactoperoxidase isoform 1 preproprotein [Homo sapiens]
Length = 712
Score = 540 bits (1390), Expect = e-153
Identities = 304/701 (43%), Positives = 413/701 (58%), Gaps = 30/701 (4%)
Query: 37 SRVSSVLEESKRLVDTAMYATMQRNLKKRGILSPA--QLLSFSKLPEPTSGVIARAAEIM 94
S +S + ++K V+ A + R +P QL + K + + R ++
Sbjct: 32 SAISDTVSQAKVQVNKAFLDSRTRLKTAMSSETPTSRQLSEYLKHAKGRTRTAIRNGQVW 91
Query: 95 ETSIQAMKRKVNLKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPI 154
E S++ +++K +L + TD S DL S+ + GC +C + C + YR I
Sbjct: 92 EESLKRLRQKASLT-----NVTDP-SLDLTSLSLEV-GCGAPAPVVRC-DPC--SPYRTI 141
Query: 155 TGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQ 214
TG CNNR P GA+N ALARWLP YEDG S P GW PG NGFPLP REV+ ++
Sbjct: 142 TGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSNKIVG 201
Query: 215 VSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQL 274
NE D S L M WGQ +DHD+ F P + ++ A C C + CFPI
Sbjct: 202 YLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCFPIMF 261
Query: 275 PEEARPAAGTA--CLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDASTVYGS 332
P P AGT C+PF+R+ C T +L R+Q+N LTSFLDAS VY S
Sbjct: 262 PPND-PKAGTQGKCMPFFRAGFVCPTPPYKSL--------AREQINALTSFLDASFVYSS 312
Query: 333 SPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPGETRGPCFLA 392
P+L +LRN +S GL+ V+ + D G YLP+ + P+ C I R PCFLA
Sbjct: 313 EPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPY-DSKKPSPCE---FINTTARVPCFLA 368
Query: 393 GDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITLRD 452
GD RASE L HTL+LREHNRLA LK LN W + +YQEARK++GA QIIT RD
Sbjct: 369 GDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRD 428
Query: 453 YIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASFQEHP 512
Y+P +LG + Q+++ PY+GY + +P +SNVF T AFRFGH + + RLD ++Q
Sbjct: 429 YLPILLG-DHMQKWIPPYQGYSESVDPRISNVF-TFAFRFGHLEVPSSMFRLDENYQPWG 486
Query: 513 DLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLSNS-S 571
P L LH FF+ W +++ GG+DPL+RGLLA+ +KL Q+++M EL +LF ++
Sbjct: 487 PEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIH 546
Query: 572 TLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDLYKHPDN 631
DLA+IN QR RDHG PGYN WR FC L + +T +L+T + S+ +A K+L LY PDN
Sbjct: 547 GFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYGTPDN 606
Query: 632 IDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRELEKHSL 691
ID+W+G +AE + R R GPL ACL+GKQ + +RDGD FWWEN VFT+ Q+ L+K S
Sbjct: 607 IDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSLQKMSF 666
Query: 692 SRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAW 732
SR++CDNT +T+VP D F +P DF C +I ++L W
Sbjct: 667 SRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPW 707
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 539 bits (1388), Expect = e-153
Identities = 298/706 (42%), Positives = 420/706 (59%), Gaps = 25/706 (3%)
Query: 39 VSSVLEESKRLVDTAMYATMQRNLKKRGILSPAQLLSFSKLP-EPTSGVIARAAEIMETS 97
V++ + E+ VD A+ +T R SP LL+ + P +P + ARA EI E +
Sbjct: 624 VATSIVEAIATVDRAINSTRTHLFDSRP-RSPNDLLALFRYPRDPYTVEQARAGEIFERT 682
Query: 98 IQAMKRKVNLKTQ-----QSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLANKYR 152
+Q ++ V S H D +S L++IAN+SGC + C + C KYR
Sbjct: 683 LQLIQEHVQHGLMVDLNGTSYHYNDLVSPQYLNLIANLSGCTAHRRVNNCSDMCFHQKYR 742
Query: 153 PITGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREVTRHV 212
G CNN HP WGAS TA R L VYE+GF+ PRG NP LYNG LP R V+ +
Sbjct: 743 THDGTCNNLQHPMWGASLTAFERLLKSVYENGFNTPRGINPHRLYNGHALPMPRLVSTTL 802
Query: 213 IQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNPCFPI 272
I E VT D++++ +LM WGQ++DHD+ T + S+A F G C C N PCF +
Sbjct: 803 I--GTETVTPDEQFTHMLMQWGQFLDHDLDSTVVALSQARFSDGQHCSNVCSNDPPCFSV 860
Query: 273 QLP-EEARPAAGTACLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDASTVYG 331
+P ++R +G C+ F RSS CG+G L +++ PR+Q+N LTS++DAS VYG
Sbjct: 861 MIPPNDSRARSGARCMFFVRSSPVCGSGMTSLL---MNSVYPREQINQLTSYIDASNVYG 917
Query: 332 SSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPGETRGPCFL 391
S+ R +R+ S GLLR ++ SG+ LPF P C + E+ PCFL
Sbjct: 918 STEHEARSIRDLASHRGLLR-QGIVQRSGKPLLPFATG-PPTECMRDEN---ESPIPCFL 972
Query: 392 AGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITLR 451
AGD RA+E LT++HTLW REHNR+A L LN HW D +Y E RK+VGA Q IT +
Sbjct: 973 AGDHRANEQLGLTSMHTLWFREHNRIATELLKLNPHWDGDTIYYETRKIVGAEIQHITYQ 1032
Query: 452 DYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASFQE- 510
++P+ILG E + +G Y GYD N + N F+TAAFRFGH ++PL+ RLD +FQ
Sbjct: 1033 HWLPKILG-EVGMRTLGEYHGYDPGINAGIFNAFATAAFRFGHTLVNPLLYRLDENFQPI 1091
Query: 511 -HPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLSN 569
LP LH+AFFSP+ ++ GG+DPL+RGL K++V QL+N ELTERLF +++
Sbjct: 1092 AQDHLP---LHKAFFSPFRIVNEGGIDPLLRGLFGVAGKMRVPSQLLNTELTERLFSMAH 1148
Query: 570 SSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDLYKHP 629
+ LDLA+IN+QRGRDHG+P Y+++R +C L T DL I + + +K+ LY
Sbjct: 1149 TVALDLAAINIQRGRDHGIPPYHDYRVYCNLSAAHTFEDLKNEIKNPEIREKLKRLYGST 1208
Query: 630 DNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRELEKH 689
NID++ + E+ +P +R GP CL+ Q K LRDGD W+EN VF+ AQ ++++
Sbjct: 1209 LNIDLFPALVVEDLVPGSRLGPTLMCLLSTQFKRLRDGDRLWYENPGVFSPAQLTQIKQT 1268
Query: 690 SLSRVICDNT-GLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRE 734
SL+R++CDN +TRV D F+V +FP + SCD I ++L W++
Sbjct: 1269 SLARILCDNADNITRVQSDVFRVAEFPHGYGSCDEIPRVDLRVWQD 1314
>gi|231569458 lactoperoxidase isoform 3 preproprotein [Homo sapiens]
Length = 629
Score = 533 bits (1373), Expect = e-151
Identities = 279/585 (47%), Positives = 364/585 (62%), Gaps = 18/585 (3%)
Query: 151 YRPITGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREVTR 210
YR ITG CNNR P GA+N ALARWLP YEDG S P GW PG NGFPLP REV+
Sbjct: 55 YRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSN 114
Query: 211 HVIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNPCF 270
++ NE D S L M WGQ +DHD+ F P + ++ A C C + CF
Sbjct: 115 KIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCF 174
Query: 271 PIQLPEEARPAAGTA--CLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDAST 328
PI P P AGT C+PF+R+ C T +L R+Q+N LTSFLDAS
Sbjct: 175 PIMFPPND-PKAGTQGKCMPFFRAGFVCPTPPYKSL--------AREQINALTSFLDASF 225
Query: 329 VYGSSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPGETRGP 388
VY S P+L +LRN +S GL+ V+ + D G YLP+ + P+ C I R P
Sbjct: 226 VYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPY-DSKKPSPCE---FINTTARVP 281
Query: 389 CFLAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQII 448
CFLAGD RASE L HTL+LREHNRLA LK LN W + +YQEARK++GA QII
Sbjct: 282 CFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQII 341
Query: 449 TLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASF 508
T RDY+P +LG + Q+++ PY+GY + +P +SNVF T AFRFGH + + RLD ++
Sbjct: 342 TFRDYLPILLG-DHMQKWIPPYQGYSESVDPRISNVF-TFAFRFGHLEVPSSMFRLDENY 399
Query: 509 QEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLS 568
Q P L LH FF+ W +++ GG+DPL+RGLLA+ +KL Q+++M EL +LF +
Sbjct: 400 QPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPT 459
Query: 569 NS-STLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDLYK 627
+ DLA+IN QR RDHG PGYN WR FC L + +T +L+T + S+ +A K+L LY
Sbjct: 460 HRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYG 519
Query: 628 HPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRELE 687
PDNID+W+G +AE + R R GPL ACL+GKQ + +RDGD FWWEN VFT+ Q+ L+
Sbjct: 520 TPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSLQ 579
Query: 688 KHSLSRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAW 732
K S SR++CDNT +T+VP D F +P DF C +I ++L W
Sbjct: 580 KMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPW 624
>gi|126517478 peroxidasin homolog-like [Homo sapiens]
Length = 1463
Score = 474 bits (1220), Expect = e-133
Identities = 273/702 (38%), Positives = 390/702 (55%), Gaps = 23/702 (3%)
Query: 40 SSVLEESKRLVDTAMYATMQRNLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQ 99
SS+L+ +R VD+A+ +T + ++ S L F +P +ARA EI E ++Q
Sbjct: 612 SSILDAVQR-VDSAINSTRRHLFSQKPHTSSDLLAQFHYPRDPLIVEMARAGEIFEHTLQ 670
Query: 100 AMKRKV------NLKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLANKYRP 153
++ +V +L+ ++ ++ D +S LS+IAN+SGC P C N C KYR
Sbjct: 671 LIRERVKQGLTVDLEGKEFRY-NDLVSPRSLSLIANLSGCTARRPLPNCSNRCFHAKYRA 729
Query: 154 ITGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVI 213
G CNN P WGA+ TA AR L P Y DG PRG + + PLPP R V +
Sbjct: 730 HDGTCNNLQQPTWGAALTAFARLLQPAYRDGIRAPRGLGLP-VGSRQPLPPPRLVA--TV 786
Query: 214 QVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQ 273
VT D Y+ +LM WG +++HD+ T + S A F G C C N PCFP+
Sbjct: 787 WARAAAVTPDHSYTRMLMHWGWFLEHDLDHTVPALSTARFSDGRPCSSVCTNDPPCFPMN 846
Query: 274 LPEEARPAAGTACLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDASTVYGSS 333
C+ F RSS AC +G A + + R+Q+N T+++D S VYGSS
Sbjct: 847 TRHADPRGTHAPCMLFARSSPACASGRPSA---TVDSVYAREQINQQTAYIDGSNVYGSS 903
Query: 334 PALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPGETRGPCFLAG 393
+ LR+ + GLL+ SG+ LPF P CA + E PCFLAG
Sbjct: 904 ERESQALRDPSVPRGLLKTGFPWPPSGKPLLPF-STGPPTECARQ-----EQESPCFLAG 957
Query: 394 DGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITLRDY 453
D RA+E +L A+HTLW REHNR+A L ALN HW + VYQEARK+VGA Q IT +
Sbjct: 958 DHRANEHLALAAMHTLWFREHNRVATELSALNPHWEGNTVYQEARKIVGAELQHITYSHW 1017
Query: 454 IPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASFQEHPD 513
+P++LG + G Y GY+ N + N F+TAAFRFGH I+P++ RL+A+ E +
Sbjct: 1018 LPKVLGDPGTRMLRG-YRGYNPNVNAGIINSFATAAFRFGHTLINPILYRLNATLGEISE 1076
Query: 514 LPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLSNSSTL 573
L H+A FSP +++ GG+DP++RGL AK + L++ ELT+RLF + S+ +
Sbjct: 1077 -GHLPFHKALFSPSRIIKEGGIDPVLRGLFGVAAKWRAPSYLLSPELTQRLFSAAYSAAV 1135
Query: 574 DLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDLYKHPDNID 633
D A+ +QRGRDHG+P Y ++R FC L ++ DL I + K+ LY P +ID
Sbjct: 1136 DSAATIIQRGRDHGIPPYVDFRVFCNLTSVKNFEDLQNEIKDSEIRQKLRKLYGSPGDID 1195
Query: 634 VWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRELEKHSLSR 693
+W + E+ +P R GP CL Q + LRDGD FW+EN VFT AQ +L++ SLSR
Sbjct: 1196 LWPALMVEDLIPGTRVGPTLMCLFVTQFQRLRDGDRFWYENPGVFTPAQLTQLKQASLSR 1255
Query: 694 VICDN-TGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRE 734
V+CDN + +V D F ++P+D+ +C I ++L W++
Sbjct: 1256 VLCDNGDSIQQVQADVFVKAEYPQDYLNCSEIPKVDLRVWQD 1297
>gi|20149640 dual oxidase 1 precursor [Homo sapiens]
Length = 1551
Score = 130 bits (328), Expect = 4e-30
Identities = 155/561 (27%), Positives = 241/561 (42%), Gaps = 74/561 (13%)
Query: 156 GACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGW----NPGFLYNGFPLPPVREVTRH 211
G NN RWG+ + L R +P Y DG QP G NP L N P
Sbjct: 34 GWYNNLMEHRWGSKGSRLQRLVPASYADGVYQPLGEPHLPNPRDLSNTISRGPAG----- 88
Query: 212 VIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNPCFP 271
+ + N V L + +G ++ D+ A F + +P F
Sbjct: 89 LASLRNRTV--------LGVFFGYHVLSDLVSVETPGCPAEF-----LNIRIPPGDPMFD 135
Query: 272 IQLPEEARPAAGTACLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDASTVYG 331
P++ G LPF RS TG S +NPR N +T +LD S +YG
Sbjct: 136 ---PDQR----GDVVLPFQRSRWDPETGR--------SPSNPRDPANQVTGWLDGSAIYG 180
Query: 332 SSPALERQLRNWTSAEGLLRVHARL-RDSGRAYLPFVPPRAPAACAPEPGIPGETRGPCF 390
SS + LR+++ + RDS L + AP+P +
Sbjct: 181 SSHSWSDALRSFSRGQLASGPDPAFPRDSQNPLLMWA--------APDPATGQNGPRGLY 232
Query: 391 LAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITL 450
G R + P L AL LW R HN A L + W + ++Q ARK V A +Q I +
Sbjct: 233 AFGAERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAV 292
Query: 451 RDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDAS--F 508
+++P L Q+ + Y GY +P++S+ F A+ +F + P V +AS F
Sbjct: 293 YEWLPSFL-----QKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVPPGVYMRNASCHF 347
Query: 509 Q-----EHPDLPGLWLHQAFFSPW--TLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELT 561
Q L + +++S +L +D L+ G+ ++ A + +D ++ E++
Sbjct: 348 QGVINRNSSVSRALRVCNSYWSREHPSLQSAEDVDALLLGMASQIA--EREDHVLVEDVR 405
Query: 562 ERLFVLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADK 621
+ S D + LQRGRD GLP Y + R GL + D++ A+ SRS D
Sbjct: 406 DFWPGPLKFSRTDHLASCLQRGRDLGLPSYTKARAALGLSPITRWQDINPAL-SRS-NDT 463
Query: 622 ILDLYKHPDNIDV-WL----GGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSH 676
+L+ N D+ WL GGL E+ GPLF+ ++ +Q LRDGD +W+EN+
Sbjct: 464 VLEATAALYNQDLSWLELLPGGLLES---HRDPGPLFSTIVLEQFVRLRDGDRYWFENTR 520
Query: 677 --VFTDAQRRELEKHSLSRVI 695
+F+ + E+ +L V+
Sbjct: 521 NGLFSKKEIEEIRNTTLQDVL 541
>gi|28872751 dual oxidase 1 precursor [Homo sapiens]
Length = 1551
Score = 130 bits (328), Expect = 4e-30
Identities = 155/561 (27%), Positives = 241/561 (42%), Gaps = 74/561 (13%)
Query: 156 GACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGW----NPGFLYNGFPLPPVREVTRH 211
G NN RWG+ + L R +P Y DG QP G NP L N P
Sbjct: 34 GWYNNLMEHRWGSKGSRLQRLVPASYADGVYQPLGEPHLPNPRDLSNTISRGPAG----- 88
Query: 212 VIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNPCFP 271
+ + N V L + +G ++ D+ A F + +P F
Sbjct: 89 LASLRNRTV--------LGVFFGYHVLSDLVSVETPGCPAEF-----LNIRIPPGDPMFD 135
Query: 272 IQLPEEARPAAGTACLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDASTVYG 331
P++ G LPF RS TG S +NPR N +T +LD S +YG
Sbjct: 136 ---PDQR----GDVVLPFQRSRWDPETGR--------SPSNPRDPANQVTGWLDGSAIYG 180
Query: 332 SSPALERQLRNWTSAEGLLRVHARL-RDSGRAYLPFVPPRAPAACAPEPGIPGETRGPCF 390
SS + LR+++ + RDS L + AP+P +
Sbjct: 181 SSHSWSDALRSFSRGQLASGPDPAFPRDSQNPLLMWA--------APDPATGQNGPRGLY 232
Query: 391 LAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITL 450
G R + P L AL LW R HN A L + W + ++Q ARK V A +Q I +
Sbjct: 233 AFGAERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAV 292
Query: 451 RDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDAS--F 508
+++P L Q+ + Y GY +P++S+ F A+ +F + P V +AS F
Sbjct: 293 YEWLPSFL-----QKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVPPGVYMRNASCHF 347
Query: 509 Q-----EHPDLPGLWLHQAFFSPW--TLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELT 561
Q L + +++S +L +D L+ G+ ++ A + +D ++ E++
Sbjct: 348 QGVINRNSSVSRALRVCNSYWSREHPSLQSAEDVDALLLGMASQIA--EREDHVLVEDVR 405
Query: 562 ERLFVLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADK 621
+ S D + LQRGRD GLP Y + R GL + D++ A+ SRS D
Sbjct: 406 DFWPGPLKFSRTDHLASCLQRGRDLGLPSYTKARAALGLSPITRWQDINPAL-SRS-NDT 463
Query: 622 ILDLYKHPDNIDV-WL----GGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSH 676
+L+ N D+ WL GGL E+ GPLF+ ++ +Q LRDGD +W+EN+
Sbjct: 464 VLEATAALYNQDLSWLELLPGGLLES---HRDPGPLFSTIVLEQFVRLRDGDRYWFENTR 520
Query: 677 --VFTDAQRRELEKHSLSRVI 695
+F+ + E+ +L V+
Sbjct: 521 NGLFSKKEIEEIRNTTLQDVL 541
>gi|132566532 dual oxidase 2 precursor [Homo sapiens]
Length = 1548
Score = 120 bits (300), Expect = 7e-27
Identities = 118/430 (27%), Positives = 191/430 (44%), Gaps = 48/430 (11%)
Query: 283 GTACLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDASTVYGSSPALERQLRN 342
G LPF RS TG S +NPR N +T +LD S +YGSS + LR+
Sbjct: 146 GDVVLPFQRSRWDPETGR--------SPSNPRDLANQVTGWLDGSAIYGSSHSWSDALRS 197
Query: 343 WTSAEGLLRVHARL-RDSGRAYLPFVPPRAPAACAPEPGIPGETRGPCFLAGDGRASEVP 401
++ + RDS L + AP+P + G R + P
Sbjct: 198 FSGGQLASGPDPAFPRDSQNPLLMWA--------APDPATGQNGPRGLYAFGAERGNREP 249
Query: 402 SLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPE 461
L AL LW R HN A L + W + ++Q ARK V A +Q I + +++P L
Sbjct: 250 FLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAVYEWLPSFL--- 306
Query: 462 AFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDAS----------FQEH 511
Q+ + Y GY +P++S F A+ +F + P V +AS FQ
Sbjct: 307 --QKTLPEYTGYRPFLDPSISPEFVVASEQFFSTMVPPGVYMRNASCHFRKVLNKGFQSS 364
Query: 512 PDL---PGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLS 568
L W+ + +P L ++ L+ G+ ++ ++L +D ++ E+L +
Sbjct: 365 QALRVCNNYWIRE---NP-NLNSTQEVNELLLGMASQISEL--EDNIVVEDLRDYWPGPG 418
Query: 569 NSSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDLYKH 628
S D + ++QRGRD GLP Y++ GL +DL+ + V + LY
Sbjct: 419 KFSRTDYVASSIQRGRDMGLPSYSQALLAFGLDIPRNWSDLNPNV-DPQVLEATAALYNQ 477
Query: 629 P-DNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSH--VFTDAQRRE 685
+++ LGGL E+ GPLF+ ++ Q LRDGD +W+EN+ +F+ + +
Sbjct: 478 DLSQLELLLGGLLES---HGDPGPLFSAIVLDQFVRLRDGDRYWFENTRNGLFSKKEIED 534
Query: 686 LEKHSLSRVI 695
+ +L V+
Sbjct: 535 IRNTTLRDVL 544
>gi|4506265 prostaglandin-endoperoxide synthase 2 precursor [Homo
sapiens]
Length = 604
Score = 56.6 bits (135), Expect = 1e-07
Identities = 40/142 (28%), Positives = 63/142 (44%), Gaps = 9/142 (6%)
Query: 318 NGLTSFLDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAP 377
NGL +D + +YG + A +R+LR + + ++ G Y P V P
Sbjct: 208 NGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQII-----DGEMYPPTVKDTQAEMIYP 262
Query: 378 EPGIPGETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEA 437
P +P R F G VP L T+WLREHNR+ LK + W + ++Q +
Sbjct: 263 -PQVPEHLR---FAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTS 318
Query: 438 RKVVGALHQIITLRDYIPRILG 459
R ++ I + DY+ + G
Sbjct: 319 RLILIGETIKIVIEDYVQHLSG 340
>gi|18104969 prostaglandin-endoperoxide synthase 1 isoform 2
precursor [Homo sapiens]
Length = 562
Score = 50.1 bits (118), Expect = 9e-06
Identities = 39/136 (28%), Positives = 61/136 (44%), Gaps = 9/136 (6%)
Query: 324 LDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPG 383
+D +YG + LERQ + +G L+ G Y P V AP GIP
Sbjct: 227 VDLGHIYGDN--LERQYQLRLFKDGKLKYQVL---DGEMYPPSVE-EAPVLMHYPRGIPP 280
Query: 384 ETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGA 443
+++ G +P L TLWLREHNR+ LKA + W + ++Q R ++
Sbjct: 281 QSQ---MAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIG 337
Query: 444 LHQIITLRDYIPRILG 459
I + +Y+ ++ G
Sbjct: 338 ETIKIVIEEYVQQLSG 353
>gi|18104967 prostaglandin-endoperoxide synthase 1 isoform 1
precursor [Homo sapiens]
Length = 599
Score = 50.1 bits (118), Expect = 9e-06
Identities = 39/136 (28%), Positives = 61/136 (44%), Gaps = 9/136 (6%)
Query: 324 LDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPG 383
+D +YG + LERQ + +G L+ G Y P V AP GIP
Sbjct: 227 VDLGHIYGDN--LERQYQLRLFKDGKLKYQVL---DGEMYPPSVE-EAPVLMHYPRGIPP 280
Query: 384 ETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGA 443
+++ G +P L TLWLREHNR+ LKA + W + ++Q R ++
Sbjct: 281 QSQ---MAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIG 337
Query: 444 LHQIITLRDYIPRILG 459
I + +Y+ ++ G
Sbjct: 338 ETIKIVIEEYVQQLSG 353
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 47.0 bits (110), Expect = 8e-05
Identities = 22/55 (40%), Positives = 28/55 (50%), Gaps = 1/55 (1%)
Query: 741 KCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEG-WDFQPPLC 794
KC PE++ NG ++ + YSC GY LQG + CT G WD PP C
Sbjct: 1904 KCSSPENINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPAC 1958
Score = 45.1 bits (105), Expect = 3e-04
Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 2/64 (3%)
Query: 742 CGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCK--DSGR 799
C P+ +ENG + S +++YSC G+++ G TC + GW P C D G
Sbjct: 2556 CDSPQPIENGFVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEESGWSSSIPTCMPIDCGL 2615
Query: 800 LPRV 803
P +
Sbjct: 2616 PPHI 2619
Score = 43.9 bits (102), Expect = 7e-04
Identities = 22/67 (32%), Positives = 30/67 (44%), Gaps = 3/67 (4%)
Query: 732 WRETFP--QDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEG-WD 788
W FP + CG + N V+ YSCR GY +QG L CT++G W
Sbjct: 3052 WSSGFPHCEHTSCGSLPMIPNAFISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWS 3111
Query: 789 FQPPLCK 795
P+C+
Sbjct: 3112 QPYPVCE 3118
Score = 43.5 bits (101), Expect = 9e-04
Identities = 32/126 (25%), Positives = 49/126 (38%), Gaps = 5/126 (3%)
Query: 727 MNLEAWRETFPQDDK--CGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQ 784
+N W + P ++ CG P +ENG + + Y C +GY L G ++ CT
Sbjct: 1673 LNQGQWTQPLPHCERISCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTD 1732
Query: 785 EG-WDFQPPLCKDSGRLPRVTWISMSLAALLIGGFAGLTSTVICRWTRTGTKSTLPISET 843
G W+ P C D + S + L + G + + +T G PI
Sbjct: 1733 NGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDG--SYICSCVPPYTGDGKNCAEPIKCK 1790
Query: 844 GGGTPE 849
G PE
Sbjct: 1791 APGNPE 1796
Score = 43.5 bits (101), Expect = 9e-04
Identities = 19/55 (34%), Positives = 29/55 (52%), Gaps = 1/55 (1%)
Query: 741 KCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEG-WDFQPPLC 794
+C P+ + NG F + + + + YSC G+ L+G LTC + G WD P C
Sbjct: 2497 ECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSC 2551
Score = 42.7 bits (99), Expect = 0.001
Identities = 21/71 (29%), Positives = 33/71 (46%), Gaps = 5/71 (7%)
Query: 732 WRETFPQDD----KCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQ-EG 786
W F + CG PES E+G V + + ++Y C GYEL+G + C +
Sbjct: 3227 WEPPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQ 3286
Query: 787 WDFQPPLCKDS 797
W +CK++
Sbjct: 3287 WSGGVAICKET 3297
Score = 42.4 bits (98), Expect = 0.002
Identities = 24/74 (32%), Positives = 34/74 (45%), Gaps = 2/74 (2%)
Query: 730 EAWRETFPQDDK--CGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGW 787
E W +T + +K CG P VEN ++ YSC GY L+G + C + G
Sbjct: 3402 ETWTQTSAKCEKISCGPPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGT 3461
Query: 788 DFQPPLCKDSGRLP 801
PP+C+ R P
Sbjct: 3462 WTSPPICRAVCRFP 3475
Score = 41.6 bits (96), Expect = 0.003
Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 1/56 (1%)
Query: 741 KCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEG-WDFQPPLCK 795
+C P + NG + + + + C GY L G +LTC +G WD + PLCK
Sbjct: 2890 RCATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCK 2945
Score = 39.3 bits (90), Expect = 0.016
Identities = 30/118 (25%), Positives = 50/118 (42%), Gaps = 14/118 (11%)
Query: 692 SRVICDNTGLTR------VPMDAFQVGKFPEDFESCDSITGMNLEAWRETFPQDDK---- 741
SR+ C + G + +D VG + SC ++ G + + + D K
Sbjct: 1726 SRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAE 1785
Query: 742 ---CGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEG-WDFQPPLCK 795
C P + ENG + + +SC+ GY+L G ++TC + G W+ P CK
Sbjct: 1786 PIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCK 1843
Score = 39.3 bits (90), Expect = 0.016
Identities = 22/60 (36%), Positives = 30/60 (50%), Gaps = 3/60 (5%)
Query: 738 QDDKCGFPESVENGDF-VHCEESGRRVLVYSCRHGYELQGREQLTCTQEG-WDFQPPLCK 795
++ +C P NG + +G V VYSC GY L+G + CT+ G W PLCK
Sbjct: 3295 KETRCETPLEFLNGKADIENRTTGPNV-VYSCNRGYSLEGPSEAHCTENGTWSHPVPLCK 3353
Score = 37.7 bits (86), Expect = 0.048
Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 3/66 (4%)
Query: 741 KCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEG-WDFQPPLCK--DS 797
+CG P S+ NG S ++ YSC G+ ++G ++ TC G W P C
Sbjct: 2145 RCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTCHPVSC 2204
Query: 798 GRLPRV 803
G P+V
Sbjct: 2205 GEPPKV 2210
Score = 37.4 bits (85), Expect = 0.062
Identities = 21/75 (28%), Positives = 30/75 (40%), Gaps = 3/75 (4%)
Query: 724 ITGMNLEAWRETFP--QDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLT 781
IT + W P + CG P ENG + + Y C GY L G ++ +
Sbjct: 1827 ITCLESGEWNHLIPYCKAVSCGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKESS 1886
Query: 782 C-TQEGWDFQPPLCK 795
C W PP+C+
Sbjct: 1887 CLANSSWSHSPPVCE 1901
Score = 37.4 bits (85), Expect = 0.062
Identities = 19/54 (35%), Positives = 23/54 (42%), Gaps = 1/54 (1%)
Query: 742 CGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQE-GWDFQPPLC 794
C P V NG + L Y C GY L G E+ TC + WD P+C
Sbjct: 2775 CKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPIC 2828
Score = 32.7 bits (73), Expect = 1.5
Identities = 14/54 (25%), Positives = 25/54 (46%), Gaps = 1/54 (1%)
Query: 742 CGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEG-WDFQPPLC 794
CG P ++++ + R + Y+C+ GY L G + + C +G W C
Sbjct: 1963 CGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQC 2016
Score = 32.0 bits (71), Expect = 2.6
Identities = 17/56 (30%), Positives = 25/56 (44%), Gaps = 1/56 (1%)
Query: 741 KCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQ-EGWDFQPPLCK 795
+C P + ENG E S + YSC+ G+ L G + C + W P C+
Sbjct: 2716 ECDLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCE 2771
Score = 31.6 bits (70), Expect = 3.4
Identities = 19/47 (40%), Positives = 25/47 (53%), Gaps = 4/47 (8%)
Query: 742 CGFPESVENGDFVHCE--ESGRRVLVYSCRHGYELQGREQLTCTQEG 786
CG P ++NG F+ E E G +V + C GYEL G TC + G
Sbjct: 2264 CGKPPPIQNG-FMKGENFEVGSKVQFF-CNEGYELVGDSSWTCQKSG 2308
Score = 31.6 bits (70), Expect = 3.4
Identities = 18/56 (32%), Positives = 28/56 (50%), Gaps = 1/56 (1%)
Query: 741 KCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTC-TQEGWDFQPPLCK 795
KC P +EN + + V+ +SC+ G+ LQG L C + W+ P+CK
Sbjct: 2322 KCPEPPLLENQLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCK 2377
Score = 31.2 bits (69), Expect = 4.5
Identities = 19/67 (28%), Positives = 28/67 (41%), Gaps = 3/67 (4%)
Query: 732 WRETFPQ--DDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEG-WD 788
W P+ +C PE + NG + +Y+C+ G+EL G C + G W
Sbjct: 2428 WSSPLPECVPVECPQPEEIPNGIIDVQGLAYLSTALYTCKPGFELVGNTTTLCGENGHWL 2487
Query: 789 FQPPLCK 795
P CK
Sbjct: 2488 GGKPTCK 2494
Score = 31.2 bits (69), Expect = 4.5
Identities = 13/30 (43%), Positives = 17/30 (56%), Gaps = 1/30 (3%)
Query: 766 YSCRHGYELQGREQLTCTQEG-WDFQPPLC 794
Y+C GYEL G L C ++G W+ P C
Sbjct: 2683 YTCNPGYELLGNPVLICQEDGTWNGSAPSC 2712
>gi|5031695 H factor (complement)-like 3 [Homo sapiens]
Length = 270
Score = 43.5 bits (101), Expect = 9e-04
Identities = 21/60 (35%), Positives = 33/60 (55%), Gaps = 4/60 (6%)
Query: 740 DKCGFPESVENGD---FVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKD 796
+KCG P ++NGD F+ + + Y C++ Y+L+G Q+TC W +PP C D
Sbjct: 147 EKCGPPPPIDNGDITSFLLSVYAPGSSVEYQCQNLYQLEGNNQITCRNGQWS-EPPKCLD 205
Score = 35.8 bits (81), Expect = 0.18
Identities = 27/74 (36%), Positives = 33/74 (44%), Gaps = 11/74 (14%)
Query: 730 EAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYS-----CRHGYELQGRE-QLTCT 783
E W T C FP VENG H E SG+ L C GY LQ E ++C
Sbjct: 75 EGWSPTPKCLRLCFFP-FVENG---HSESSGQTHLEGDTVQIICNTGYRLQNNENNISCV 130
Query: 784 QEGWDFQPPLCKDS 797
+ GW PP C+ +
Sbjct: 131 ERGWS-TPPKCRST 143
>gi|62739186 complement factor H isoform a precursor [Homo sapiens]
Length = 1231
Score = 42.4 bits (98), Expect = 0.002
Identities = 25/64 (39%), Positives = 33/64 (51%), Gaps = 6/64 (9%)
Query: 738 QDDKCGFPESVENGDFVHCE----ESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPL 793
+D C P +V+N V + SG RV Y CR YE+ G E++ C W +PP
Sbjct: 1044 RDTSCVNPPTVQNAYIVSRQMSKYPSGERVR-YQCRSPYEMFGDEEVMCLNGNWT-EPPQ 1101
Query: 794 CKDS 797
CKDS
Sbjct: 1102 CKDS 1105
Score = 39.3 bits (90), Expect = 0.016
Identities = 19/57 (33%), Positives = 30/57 (52%), Gaps = 4/57 (7%)
Query: 741 KCGFPESVENGDFVHCEES---GRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLC 794
KCG P ++NGD S + Y C++ Y+L+G +++TC W +PP C
Sbjct: 1108 KCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITCRNGQWS-EPPKC 1163
Score = 32.3 bits (72), Expect = 2.0
Identities = 22/69 (31%), Positives = 29/69 (42%), Gaps = 6/69 (8%)
Query: 738 QDDKCGFPESVENGDFV----HCEESGRRVLVYSCRHGYELQGR-EQLTCTQEGWDFQPP 792
Q CG P G F + E G + VY+C GY+L G C +GW P
Sbjct: 81 QKRPCGHPGDTPFGTFTLTGGNVFEYGVKA-VYTCNEGYQLLGEINYRECDTDGWTNDIP 139
Query: 793 LCKDSGRLP 801
+C+ LP
Sbjct: 140 ICEVVKCLP 148
>gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens]
Length = 3565
Score = 42.4 bits (98), Expect = 0.002
Identities = 26/76 (34%), Positives = 37/76 (48%), Gaps = 7/76 (9%)
Query: 727 MNLEAWRETFP--QDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLT--C 782
+ + W P Q CG PES NG F E + +VY C G++L+ +Q T C
Sbjct: 2479 LGMYQWDSLTPLCQAVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVC 2538
Query: 783 TQEG-WD--FQPPLCK 795
++G W +PP CK
Sbjct: 2539 QEDGLWSNKGKPPTCK 2554
Score = 37.4 bits (85), Expect = 0.062
Identities = 19/54 (35%), Positives = 25/54 (46%), Gaps = 1/54 (1%)
Query: 742 CGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQE-GWDFQPPLC 794
CG P+ + NG S R +VY C G+ L G C Q+ W Q P+C
Sbjct: 2681 CGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVC 2734
Score = 36.2 bits (82), Expect = 0.14
Identities = 26/90 (28%), Positives = 35/90 (38%), Gaps = 10/90 (11%)
Query: 714 FPEDFESCDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYE 773
F DF +++ +A E P CG P + G + + YSC GY
Sbjct: 122 FTTDF----AVSAQGFKALYEVLPSHT-CGNPGEILKGVLHGTRFNIGDKIRYSCLPGYI 176
Query: 774 LQGREQLTC-----TQEGWDFQPPLCKDSG 798
L+G LTC WDF P C+ G
Sbjct: 177 LEGHAILTCIVSPGNGASWDFPAPFCRAEG 206
Score = 35.4 bits (80), Expect = 0.24
Identities = 17/57 (29%), Positives = 24/57 (42%), Gaps = 4/57 (7%)
Query: 742 CGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEG----WDFQPPLC 794
C P +NG + + C GY+LQG+ ++TC Q W PP C
Sbjct: 1392 CNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC 1448
Score = 35.4 bits (80), Expect = 0.24
Identities = 15/35 (42%), Positives = 20/35 (57%), Gaps = 3/35 (8%)
Query: 763 VLVYSCRHGYELQGREQLTC---TQEGWDFQPPLC 794
VL + C GY LQGR ++C T W++ PLC
Sbjct: 1937 VLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLC 1971
Score = 33.9 bits (76), Expect = 0.69
Identities = 16/55 (29%), Positives = 29/55 (52%), Gaps = 1/55 (1%)
Query: 742 CGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEG-WDFQPPLCK 795
CG P + +G + + + +L +SC G++L+G + TC G W P+C+
Sbjct: 2921 CGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCE 2975
Score = 33.5 bits (75), Expect = 0.90
Identities = 25/83 (30%), Positives = 32/83 (38%), Gaps = 20/83 (24%)
Query: 732 WRE--TFPQDDKCGFPESVENGDFVHCEESG---------------RRVLVYSCRHGYEL 774
W E T D GF + + D V CE+ G V++YSC GY +
Sbjct: 1192 WLEFNTNGSDTDQGFQLTYTSFDLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAM 1251
Query: 775 QGREQLTC---TQEGWDFQPPLC 794
G LTC + WD P C
Sbjct: 1252 HGSNTLTCLSGDRRVWDKPLPSC 1274
Score = 33.5 bits (75), Expect = 0.90
Identities = 20/69 (28%), Positives = 32/69 (46%), Gaps = 5/69 (7%)
Query: 732 WRETFPQDD--KCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLT--CTQEG- 786
W T P CG P ++ NG + + + + Y C GY ++ T CT++G
Sbjct: 3026 WTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGR 3085
Query: 787 WDFQPPLCK 795
W+ P+CK
Sbjct: 3086 WNPSKPVCK 3094
Score = 33.1 bits (74), Expect = 1.2
Identities = 22/60 (36%), Positives = 26/60 (43%), Gaps = 8/60 (13%)
Query: 742 CGFPESVENG------DFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEG-WDFQPPLC 794
C P VEN +F E G +L Y C+ G+ L G LTC G WD P C
Sbjct: 2797 CSDPGFVENAIRHGQQNFPESFEYGMSIL-YHCKKGFYLLGSSALTCMANGLWDRSLPKC 2855
Score = 30.8 bits (68), Expect = 5.8
Identities = 16/56 (28%), Positives = 25/56 (44%), Gaps = 3/56 (5%)
Query: 742 CGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTC---TQEGWDFQPPLC 794
C P +NG ++ + S + + + C GY L G LTC W++ P C
Sbjct: 2088 CPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRC 2143
Score = 30.8 bits (68), Expect = 5.8
Identities = 17/55 (30%), Positives = 25/55 (45%), Gaps = 1/55 (1%)
Query: 742 CGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEG-WDFQPPLCK 795
CG P + +G E + V+ ++C GY LQG + C G W P C+
Sbjct: 2739 CGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCR 2793
Score = 30.4 bits (67), Expect = 7.6
Identities = 20/62 (32%), Positives = 26/62 (41%), Gaps = 6/62 (9%)
Query: 740 DKCGFPESVENGDFVHCEESGRRVLV-YSCRHGYELQGREQLTC-----TQEGWDFQPPL 793
D C P ENG + S V +SC Y LQG + +TC T W P+
Sbjct: 347 DMCPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPI 406
Query: 794 CK 795
C+
Sbjct: 407 CR 408
Score = 30.0 bits (66), Expect = 10.0
Identities = 17/54 (31%), Positives = 23/54 (42%), Gaps = 1/54 (1%)
Query: 742 CGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEG-WDFQPPLC 794
C P V+NG + + YSC GY+L L+C G W + P C
Sbjct: 3098 CPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQC 3151
>gi|32261332 seizure related 6 homolog (mouse)-like precursor [Homo
sapiens]
Length = 1024
Score = 42.4 bits (98), Expect = 0.002
Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 3/56 (5%)
Query: 742 CGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTC---TQEGWDFQPPLC 794
C FP ++GD + V + C GYELQG + LTC ++ W Q P+C
Sbjct: 393 CNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPIC 448
Score = 36.2 bits (82), Expect = 0.14
Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 10/88 (11%)
Query: 738 QDDKCGFPESVENG--DFVHCEESGRRVLVYSCRHGYELQGREQLTCTQE-GWDFQPPLC 794
++D C ++NG H E + Y C GY++ G + LTC + W PP C
Sbjct: 741 RNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFC 800
Query: 795 K------DSGRLPRVTWISMSLAALLIG 816
+ D G + T + +S LL+G
Sbjct: 801 EKIMYCTDPGEVDHSTRL-ISDPVLLVG 827
>gi|118442839 complement factor H-related 1 [Homo sapiens]
Length = 330
Score = 41.6 bits (96), Expect = 0.003
Identities = 24/63 (38%), Positives = 32/63 (50%), Gaps = 6/63 (9%)
Query: 739 DDKCGFPESVENGDFVHCE----ESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLC 794
D C P +V+N + + SG RV Y CR YE+ G E++ C W +PP C
Sbjct: 144 DTSCVNPPTVQNAHILSRQMSKYPSGERVR-YECRSPYEMFGDEEVMCLNGNWT-EPPQC 201
Query: 795 KDS 797
KDS
Sbjct: 202 KDS 204
Score = 39.3 bits (90), Expect = 0.016
Identities = 19/57 (33%), Positives = 30/57 (52%), Gaps = 4/57 (7%)
Query: 741 KCGFPESVENGDFVHCEES---GRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLC 794
KCG P ++NGD S + Y C++ Y+L+G +++TC W +PP C
Sbjct: 207 KCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITCRNGQWS-EPPKC 262
Score = 35.8 bits (81), Expect = 0.18
Identities = 27/74 (36%), Positives = 33/74 (44%), Gaps = 11/74 (14%)
Query: 730 EAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYS-----CRHGYELQGRE-QLTCT 783
E W T C FP VENG H E SG+ L C GY LQ E ++C
Sbjct: 75 EGWSPTPKCLRLCFFP-FVENG---HSESSGQTHLEGDTVQIICNTGYRLQNNENNISCV 130
Query: 784 QEGWDFQPPLCKDS 797
+ GW PP C+ +
Sbjct: 131 ERGWS-TPPKCRST 143
>gi|4502503 complement component 4 binding protein, alpha chain
precursor [Homo sapiens]
Length = 597
Score = 41.6 bits (96), Expect = 0.003
Identities = 19/66 (28%), Positives = 30/66 (45%), Gaps = 2/66 (3%)
Query: 740 DKCGFPESVENGDFVHCEESG--RRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDS 797
D C FP + +G + + ++Y C GY L G+ +L+C+ W P CK
Sbjct: 424 DICNFPPKIAHGHYKQSSSYSFFKEEIIYECDKGYILVGQAKLSCSYSHWSAPAPQCKAL 483
Query: 798 GRLPRV 803
R P +
Sbjct: 484 CRKPEL 489
Score = 31.6 bits (70), Expect = 3.4
Identities = 25/101 (24%), Positives = 46/101 (45%), Gaps = 21/101 (20%)
Query: 720 SCDSITGMNLEAWRETFPQDDK--CGFPESVENGDFVHCEESG-------RRVLVYSCRH 770
SC ++ + WR + P +K C P+ V +G+ V SG + +V+ C+
Sbjct: 216 SC-TVENETIGVWRPSPPTCEKITCRKPD-VSHGEMV----SGFGPIYNYKDTIVFKCQK 269
Query: 771 GYELQGREQLTCTQEG-WDFQPPLCKDSG-----RLPRVTW 805
G+ L+G + C + W+ PP C+ + +P +W
Sbjct: 270 GFVLRGSSVIHCDADSKWNPSPPACEPNSCINLPDIPHASW 310
Score = 30.8 bits (68), Expect = 5.8
Identities = 22/75 (29%), Positives = 29/75 (38%), Gaps = 13/75 (17%)
Query: 732 WRETFPQDD--KCGFPESVENGDFVHCEESGRRV----LVYSCRHGYELQGREQLTCTQE 785
W PQ + KC P + NG H E + YSC + L G ++CT E
Sbjct: 163 WSHPLPQCEIVKCKPPPDIRNGR--HSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVE 220
Query: 786 G-----WDFQPPLCK 795
W PP C+
Sbjct: 221 NETIGVWRPSPPTCE 235
>gi|239758113 PREDICTED: similar to complement factor H-related 1
isoform 1 [Homo sapiens]
Length = 330
Score = 41.6 bits (96), Expect = 0.003
Identities = 24/63 (38%), Positives = 32/63 (50%), Gaps = 6/63 (9%)
Query: 739 DDKCGFPESVENGDFVHCE----ESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLC 794
D C P +V+N + + SG RV Y CR YE+ G E++ C W +PP C
Sbjct: 144 DTSCVNPPTVQNAHILSRQMSKYPSGERVR-YECRSPYEMFGDEEVMCLNGNWT-EPPQC 201
Query: 795 KDS 797
KDS
Sbjct: 202 KDS 204
Score = 39.3 bits (90), Expect = 0.016
Identities = 19/57 (33%), Positives = 30/57 (52%), Gaps = 4/57 (7%)
Query: 741 KCGFPESVENGDFVHCEES---GRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLC 794
KCG P ++NGD S + Y C++ Y+L+G +++TC W +PP C
Sbjct: 207 KCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITCRNGQWS-EPPKC 262
Score = 35.8 bits (81), Expect = 0.18
Identities = 27/74 (36%), Positives = 33/74 (44%), Gaps = 11/74 (14%)
Query: 730 EAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYS-----CRHGYELQGRE-QLTCT 783
E W T C FP VENG H E SG+ L C GY LQ E ++C
Sbjct: 75 EGWSPTPKCLRLCFFP-FVENG---HSESSGQTHLEGDTVQIICNTGYRLQNNENNISCV 130
Query: 784 QEGWDFQPPLCKDS 797
+ GW PP C+ +
Sbjct: 131 ERGWS-TPPKCRST 143
>gi|117320518 complement factor H-related 4 [Homo sapiens]
Length = 331
Score = 40.0 bits (92), Expect = 0.010
Identities = 21/62 (33%), Positives = 31/62 (50%), Gaps = 4/62 (6%)
Query: 736 FPQDDKCGFPESVENGD---FVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPP 792
+ +KCG P + NGD F+ + + Y C+ YELQG +TC+ W +PP
Sbjct: 205 YNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCSNGEWS-EPP 263
Query: 793 LC 794
C
Sbjct: 264 RC 265
>gi|168693643 decay accelerating factor for complement isoform 2
precursor [Homo sapiens]
Length = 440
Score = 39.7 bits (91), Expect = 0.013
Identities = 35/141 (24%), Positives = 60/141 (42%), Gaps = 16/141 (11%)
Query: 724 ITGMNLEAWRETFPQ--DDKCGFPESVENGDFVHCEESG---RRVLVYSCRHGYELQGRE 778
I+G +++ W + P+ + C P ++NG + E R+ + Y+C G+ + G
Sbjct: 206 ISGSSVQ-WSDPLPECREIYCPAPPQIDNG-IIQGERDHYGYRQSVTYACNKGFTMIGEH 263
Query: 779 QLTCT---QEG-WDFQPPLCKDSGRLPRVTWISMSLAALLIGGFAGLTSTVICRWTRTGT 834
+ CT EG W PP C+ +V + + T+ V +T T
Sbjct: 264 SIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVP-----TTEVSPTSQKTTT 318
Query: 835 KSTLPISETGGGTPELRCGKH 855
K+T P ++ TP R KH
Sbjct: 319 KTTTPNAQATRSTPVSRTTKH 339
>gi|10835143 decay accelerating factor for complement isoform 1
preproprotein [Homo sapiens]
Length = 381
Score = 39.7 bits (91), Expect = 0.013
Identities = 35/141 (24%), Positives = 60/141 (42%), Gaps = 16/141 (11%)
Query: 724 ITGMNLEAWRETFPQ--DDKCGFPESVENGDFVHCEESG---RRVLVYSCRHGYELQGRE 778
I+G +++ W + P+ + C P ++NG + E R+ + Y+C G+ + G
Sbjct: 206 ISGSSVQ-WSDPLPECREIYCPAPPQIDNG-IIQGERDHYGYRQSVTYACNKGFTMIGEH 263
Query: 779 QLTCT---QEG-WDFQPPLCKDSGRLPRVTWISMSLAALLIGGFAGLTSTVICRWTRTGT 834
+ CT EG W PP C+ +V + + T+ V +T T
Sbjct: 264 SIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVP-----TTEVSPTSQKTTT 318
Query: 835 KSTLPISETGGGTPELRCGKH 855
K+T P ++ TP R KH
Sbjct: 319 KTTTPNAQATRSTPVSRTTKH 339
>gi|166235140 seizure related 6 homolog (mouse)-like 2 isoform 4
[Homo sapiens]
Length = 809
Score = 39.3 bits (90), Expect = 0.016
Identities = 20/59 (33%), Positives = 27/59 (45%), Gaps = 3/59 (5%)
Query: 742 CGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTC---TQEGWDFQPPLCKDS 797
CGFP +GD + + C GY+LQG E L C T+ W+ + P C S
Sbjct: 176 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMAS 234
Score = 36.2 bits (82), Expect = 0.14
Identities = 16/34 (47%), Positives = 19/34 (55%), Gaps = 1/34 (2%)
Query: 763 VLVYSCRHGYELQGREQLTCTQE-GWDFQPPLCK 795
VL Y C GYEL G + LTC + W PP C+
Sbjct: 553 VLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQ 586
Score = 34.7 bits (78), Expect = 0.40
Identities = 20/56 (35%), Positives = 27/56 (48%), Gaps = 4/56 (7%)
Query: 743 GFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQ---EGWDFQPPLCK 795
G PE+ + H ++G L + C G+EL G +TC W QPPLCK
Sbjct: 661 GVPENGYQTLYKHHYQAGES-LRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCK 715
>gi|166235138 seizure related 6 homolog (mouse)-like 2 isoform 3
[Homo sapiens]
Length = 840
Score = 39.3 bits (90), Expect = 0.016
Identities = 20/59 (33%), Positives = 27/59 (45%), Gaps = 3/59 (5%)
Query: 742 CGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTC---TQEGWDFQPPLCKDS 797
CGFP +GD + + C GY+LQG E L C T+ W+ + P C S
Sbjct: 220 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMAS 278
Score = 36.2 bits (82), Expect = 0.14
Identities = 16/34 (47%), Positives = 19/34 (55%), Gaps = 1/34 (2%)
Query: 763 VLVYSCRHGYELQGREQLTCTQE-GWDFQPPLCK 795
VL Y C GYEL G + LTC + W PP C+
Sbjct: 597 VLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQ 630
Score = 35.4 bits (80), Expect = 0.24
Identities = 35/115 (30%), Positives = 52/115 (45%), Gaps = 12/115 (10%)
Query: 743 GFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQ---EGWDFQPPLCK---- 795
G PE+ + H ++G L + C G+EL G +TC W QPPLCK
Sbjct: 705 GVPENGYQTLYKHHYQAGES-LRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKVTQT 763
Query: 796 -DSGRLPRVTWISMSLAALL-IGGFAGLTSTVICRWTRTGTKSTLPISETGGGTP 848
D R ++ +++LA LL +G L S V +T+ KS S + +P
Sbjct: 764 TDPSR--QLEGGNLALAILLPLGLVIVLGSGVYIYYTKLQGKSLFGFSGSHSYSP 816
>gi|166235136 seizure related 6 homolog (mouse)-like 2 isoform 2
[Homo sapiens]
Length = 910
Score = 39.3 bits (90), Expect = 0.016
Identities = 20/59 (33%), Positives = 27/59 (45%), Gaps = 3/59 (5%)
Query: 742 CGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTC---TQEGWDFQPPLCKDS 797
CGFP +GD + + C GY+LQG E L C T+ W+ + P C S
Sbjct: 290 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMAS 348
Score = 36.2 bits (82), Expect = 0.14
Identities = 16/34 (47%), Positives = 19/34 (55%), Gaps = 1/34 (2%)
Query: 763 VLVYSCRHGYELQGREQLTCTQE-GWDFQPPLCK 795
VL Y C GYEL G + LTC + W PP C+
Sbjct: 667 VLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQ 700
Score = 35.4 bits (80), Expect = 0.24
Identities = 35/115 (30%), Positives = 52/115 (45%), Gaps = 12/115 (10%)
Query: 743 GFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQ---EGWDFQPPLCK---- 795
G PE+ + H ++G L + C G+EL G +TC W QPPLCK
Sbjct: 775 GVPENGYQTLYKHHYQAGES-LRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKVTQT 833
Query: 796 -DSGRLPRVTWISMSLAALL-IGGFAGLTSTVICRWTRTGTKSTLPISETGGGTP 848
D R ++ +++LA LL +G L S V +T+ KS S + +P
Sbjct: 834 TDPSR--QLEGGNLALAILLPLGLVIVLGSGVYIYYTKLQGKSLFGFSGSHSYSP 886
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,947,060
Number of Sequences: 37866
Number of extensions: 1767385
Number of successful extensions: 5279
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 42
Number of HSP's that attempted gapping in prelim test: 4904
Number of HSP's gapped (non-prelim): 346
length of query: 889
length of database: 18,247,518
effective HSP length: 111
effective length of query: 778
effective length of database: 14,044,392
effective search space: 10926536976
effective search space used: 10926536976
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.