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Search of human proteins with 28274703
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|28274703 family with sequence similarity 9, member C [Homo
sapiens]
(166 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|28274703 family with sequence similarity 9, member C [Homo sa... 331 2e-91
gi|45504371 family with sequence similarity 9, member B [Homo sa... 173 5e-44
gi|28274705 family with sequence similarity 9, member A [Homo sa... 152 1e-37
gi|24233580 synaptonemal complex protein 3 [Homo sapiens] 65 3e-11
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 41 4e-04
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 40 7e-04
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 39 0.003
gi|38569484 kinesin family member 21A [Homo sapiens] 38 0.003
gi|42476169 Paf1, RNA polymerase II associated factor, homolog [... 38 0.005
gi|22748943 hypothetical protein LOC145483 [Homo sapiens] 37 0.008
gi|4505835 polycystin 2 [Homo sapiens] 37 0.010
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do... 36 0.013
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 36 0.013
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 36 0.013
gi|148746195 trichohyalin [Homo sapiens] 35 0.029
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 35 0.029
gi|5803203 troponin T3, skeletal, fast isoform 1 [Homo sapiens] 35 0.038
gi|5454014 tripartite motif-containing 38 [Homo sapiens] 35 0.038
gi|27894339 keratin 23 [Homo sapiens] 34 0.050
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 34 0.050
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 34 0.050
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 34 0.050
gi|224591408 SH2 domain containing 4B isoform 2 [Homo sapiens] 34 0.066
gi|224591406 SH2 domain containing 4B isoform 1 [Homo sapiens] 34 0.066
gi|195546919 growth arrest-specific 7 isoform d [Homo sapiens] 33 0.086
gi|41406080 growth arrest-specific 7 isoform c [Homo sapiens] 33 0.086
gi|41406078 growth arrest-specific 7 isoform b [Homo sapiens] 33 0.086
gi|41406076 growth arrest-specific 7 isoform a [Homo sapiens] 33 0.086
gi|110347418 structural maintenance of chromosomes 2 [Homo sapiens] 33 0.086
gi|110347425 structural maintenance of chromosomes 2 [Homo sapiens] 33 0.086
>gi|28274703 family with sequence similarity 9, member C [Homo
sapiens]
Length = 166
Score = 331 bits (849), Expect = 2e-91
Identities = 166/166 (100%), Positives = 166/166 (100%)
Query: 1 MAAKDQLEVQVMAAQEMELAGKDPVSHEHEERKPVTETKEGDVTDEHGERGSFAETDEHT 60
MAAKDQLEVQVMAAQEMELAGKDPVSHEHEERKPVTETKEGDVTDEHGERGSFAETDEHT
Sbjct: 1 MAAKDQLEVQVMAAQEMELAGKDPVSHEHEERKPVTETKEGDVTDEHGERGSFAETDEHT 60
Query: 61 GVDTKELEDIAADIKEHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQLKRQKRDYRISLK 120
GVDTKELEDIAADIKEHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQLKRQKRDYRISLK
Sbjct: 61 GVDTKELEDIAADIKEHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQLKRQKRDYRISLK 120
Query: 121 LPNVLEEFITDEQKDEEGDGEKEEQIKIFQEQQKRWQQDGKGTERD 166
LPNVLEEFITDEQKDEEGDGEKEEQIKIFQEQQKRWQQDGKGTERD
Sbjct: 121 LPNVLEEFITDEQKDEEGDGEKEEQIKIFQEQQKRWQQDGKGTERD 166
>gi|45504371 family with sequence similarity 9, member B [Homo
sapiens]
Length = 186
Score = 173 bits (439), Expect = 5e-44
Identities = 97/148 (65%), Positives = 112/148 (75%), Gaps = 6/148 (4%)
Query: 12 MAAQEMELAGKDPVSHEHEERKPVTETKEGDVTDEHGERGSFAETDEHTGVDTKELEDIA 71
MAA + AGKDPV E EER TET+E DVTDEHGER FAETDEHTG +TK+ ED A
Sbjct: 1 MAAWGKKHAGKDPVRDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTA 60
Query: 72 ADIKEHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQLKRQKRDYRISLKLPNVLEEFITD 131
D L AKRKR+ K+ K CS+ KN+ K+ LR QLKRQKRDY SLKL NVLEE+ITD
Sbjct: 61 ED----LTAKRKRM-KMDKTCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITD 115
Query: 132 EQK-DEEGDGEKEEQIKIFQEQQKRWQQ 158
EQK +EE +GE+EE I+IFQEQQK+WQQ
Sbjct: 116 EQKEEEEEEGEEEELIRIFQEQQKKWQQ 143
>gi|28274705 family with sequence similarity 9, member A [Homo
sapiens]
Length = 332
Score = 152 bits (385), Expect = 1e-37
Identities = 82/138 (59%), Positives = 99/138 (71%)
Query: 2 AAKDQLEVQVMAAQEMELAGKDPVSHEHEERKPVTETKEGDVTDEHGERGSFAETDEHTG 61
AAK QLE QV AA + GKDPV E EER P TET+E DVTDEHGER FAE DEHTG
Sbjct: 55 AAKAQLEAQVRAAPAKKHTGKDPVRDECEERNPFTETREEDVTDEHGEREPFAEKDEHTG 114
Query: 62 VDTKELEDIAADIKEHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQLKRQKRDYRISLKL 121
+ T +LE IAADIK+ LAAKR+ I+ A + KN I+ L+ QLKRQKRDYR + KL
Sbjct: 115 IHTMKLEHIAADIKKGLAAKREMIKIDKAAYRKTKNTIERALKKKQLKRQKRDYRHTRKL 174
Query: 122 PNVLEEFITDEQKDEEGD 139
NVL+E+I ++QKD+E +
Sbjct: 175 LNVLKEYIAEKQKDDEAE 192
Score = 45.8 bits (107), Expect = 2e-05
Identities = 19/29 (65%), Positives = 26/29 (89%)
Query: 130 TDEQKDEEGDGEKEEQIKIFQEQQKRWQQ 158
T+E+++EE + E+EEQIK FQE+QKRWQQ
Sbjct: 261 TEEEEEEEEEEEEEEQIKAFQEKQKRWQQ 289
>gi|24233580 synaptonemal complex protein 3 [Homo sapiens]
Length = 236
Score = 64.7 bits (156), Expect = 3e-11
Identities = 48/158 (30%), Positives = 79/158 (50%), Gaps = 7/158 (4%)
Query: 2 AAKDQLEVQVMAAQEMELAGKDPVSHEHEERKPVTETKEGDVTDEHGERGSFAETDEHTG 61
+ K +E Q A + E K +S E+ V E K + +R S ++ G
Sbjct: 12 SGKPSVEDQFTRAYDFETEDKKDLSGSEED---VIEGKTAVIEKRRKKRSSAGVVEDMGG 68
Query: 62 VDTKELEDIAADIKEHLAAKRKRIEKIAKACSEIKN-RIKNVLRTTQLKRQKRDYRISLK 120
LE + DI + L AKRKR+E KA + N +I++V +T Q +RQK + S +
Sbjct: 69 EVQNMLEGVGVDINKALLAKRKRLEMYTKASLKTSNQKIEHVWKTQQDQRQKLNQEYSQQ 128
Query: 121 LPNVLEEFITDEQKDEEGDGEKEEQIKIFQEQQKRWQQ 158
+ +++ D QK EE ++E+ + +F++QQK QQ
Sbjct: 129 FLTLFQQWDLDMQKAEE---QEEKILNMFRQQQKILQQ 163
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 41.2 bits (95), Expect = 4e-04
Identities = 37/162 (22%), Positives = 77/162 (47%), Gaps = 10/162 (6%)
Query: 6 QLEVQVMAAQEMELAGKDPVSHEHEERKPVTETKEGDVTDEHGE----RGSFAETDEHTG 61
Q+ Q +E E ++ E+ V E +EG V ++ G+ G E +E G
Sbjct: 151 QVREQEGQVREQEGQVREQEGQVREQEGQVRE-QEGQVREQEGQMGEQEGQMGEQEEQMG 209
Query: 62 VDTKELEDIAADIKEHLAAKRKRIEKIAKACSEIKNRIKNVLRTT-QLKRQKRDYRISLK 120
++++ + E RK+ E++ + +++ + + V + Q+++Q+ R +
Sbjct: 210 EQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEE 269
Query: 121 LPNVLEEFIT---DEQKDEEGDGEKEEQIKIFQEQQKRWQQD 159
EE + ++ + EE GE+EEQ++ QE+Q R Q++
Sbjct: 270 QMREQEEQMLKQKEQTEQEEQTGEQEEQMR-EQEEQMREQEE 310
Score = 30.4 bits (67), Expect = 0.73
Identities = 33/161 (20%), Positives = 74/161 (45%), Gaps = 10/161 (6%)
Query: 6 QLEVQVMAAQEMELAGKDPVSHEHEERKPVTETKEGDVTDEHGERGSFAETDEHTGVDTK 65
Q + + M QE ++ ++ E EE+ K+ + T++ + G E +
Sbjct: 251 QKQEEQMRKQEEQMREQEEQMREQEEQM----LKQKEQTEQEEQTGEQEEQMREQEEQMR 306
Query: 66 ELEDIAADIKEHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQLKRQKRDYRISLKLPNVL 125
E E+ + +E + + +++ K + E K ++ + Q+ +Q+ +
Sbjct: 307 EQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWE--QKEQMWKQEEQMGEQEEQMQKQ 364
Query: 126 EEFITDEQKDEEGDGEKEEQIKIFQEQQKRWQQDGKGTERD 166
EE + +K EE ++EEQ++ QE+Q R Q++ G +++
Sbjct: 365 EEQV---RKQEEQMRKQEEQMRK-QEEQMRKQEEQMGEQKE 401
Score = 28.5 bits (62), Expect = 2.8
Identities = 24/150 (16%), Positives = 69/150 (46%), Gaps = 2/150 (1%)
Query: 15 QEMELAGKDPVSHEHEERKPVTETKEGDVTDEHGERGSFAETDEHTGVDTKELEDIAADI 74
QE ++ ++ + EE+ E + + ++ ++ E +E TG +++ + +
Sbjct: 246 QEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQM 305
Query: 75 KEHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQLKRQKRDYRISLKLPNVLEEFITDEQK 134
+E R++ E++ + ++ + + + + ++++ K + E QK
Sbjct: 306 REQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQM--WKQEEQMGEQEEQMQK 363
Query: 135 DEEGDGEKEEQIKIFQEQQKRWQQDGKGTE 164
EE ++EEQ++ +EQ ++ ++ + E
Sbjct: 364 QEEQVRKQEEQMRKQEEQMRKQEEQMRKQE 393
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 40.4 bits (93), Expect = 7e-04
Identities = 32/152 (21%), Positives = 69/152 (45%), Gaps = 4/152 (2%)
Query: 4 KDQLEVQVMAAQEMELAGKDPVSHEHEERKPVTETKEGDVTDEHGERGSFAETDEHTGVD 63
+ Q E VM+ + +++ ++P E E+ + + +E ER E ++
Sbjct: 218 ESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEA----ERARLE 273
Query: 64 TKELEDIAADIKEHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQLKRQKRDYRISLKLPN 123
+E E I A+ + +A +R RIE KA ++ + R + R + +KR ++
Sbjct: 274 AEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKE 333
Query: 124 VLEEFITDEQKDEEGDGEKEEQIKIFQEQQKR 155
+ + Q+ +E + E+ + +E++KR
Sbjct: 334 EEKRAAEERQRIKEEEKRAAEERQRIKEEEKR 365
Score = 34.7 bits (78), Expect = 0.038
Identities = 39/171 (22%), Positives = 77/171 (45%), Gaps = 20/171 (11%)
Query: 12 MAAQEMELAGKDPVSHEHEERKPVTETKEGDVTDEHG-----ERGSFAETDEHTGVDT-- 64
M ++ E A + E EER+ + ++ + DE E+ + E + +
Sbjct: 257 MEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERER 316
Query: 65 -KELEDIAADIKEHL-------AAKRKRIEKIAKACSEIKNRIKNVLRTTQLKRQKRDYR 116
+E E AA+ ++ + A +R+RI++ K +E + RIK + +RQ+ R
Sbjct: 317 MREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRA--R 374
Query: 117 ISLKLPNVLEEFITDEQKDEEGDGEKEEQIKIFQEQQK---RWQQDGKGTE 164
+ +EE ++Q +E+ +E +IK + +QK +W + K E
Sbjct: 375 AEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQE 425
Score = 29.6 bits (65), Expect = 1.2
Identities = 26/118 (22%), Positives = 53/118 (44%)
Query: 38 TKEGDVTDEHGERGSFAETDEHTGVDTKELEDIAADIKEHLAAKRKRIEKIAKACSEIKN 97
T++ + ++ ER ET+ T K A + K+ K + E+ K S +N
Sbjct: 147 TEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGEN 206
Query: 98 RIKNVLRTTQLKRQKRDYRISLKLPNVLEEFITDEQKDEEGDGEKEEQIKIFQEQQKR 155
+++ ++ + Q+ +SLK + E E++ E+G E K+ +E ++R
Sbjct: 207 QVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKER 264
Score = 26.9 bits (58), Expect = 8.0
Identities = 37/176 (21%), Positives = 76/176 (43%), Gaps = 27/176 (15%)
Query: 2 AAKDQLEVQVMAAQEMELAGKDPVSHEHEERKPVTETKEGDVTDEHGERGSFAETDEHTG 61
A +D+L+ V+ Q E K E + T KE ++ DE ++ + + +
Sbjct: 423 AQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKE-EIKDEKIKKDKEPKEEVKSF 481
Query: 62 VDTKE-LEDIAADIKEHLAAKRKRIEKI-----AKACSEIKN-----RIKNVLRTTQLKR 110
+D K+ ++ + E + K K E +A + K +++ R +L+R
Sbjct: 482 MDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRR 541
Query: 111 QKRDYRISLKLPNVLEEFITDEQKDEEGDGE-------KEEQIKIFQEQQKRWQQD 159
++ + EEF +QK +E E +EE+ K+ +E+++R +Q+
Sbjct: 542 RRGETES--------EEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQE 589
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 38.5 bits (88), Expect = 0.003
Identities = 39/157 (24%), Positives = 72/157 (45%), Gaps = 17/157 (10%)
Query: 15 QEMELAGKDPVSHEHEERKPVTETKEGDVT---------DEHGERGSFAETDEHTGVDTK 65
+E+E KD + +RK ET + VT +E E + AE D K
Sbjct: 257 EELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKK 316
Query: 66 ELEDIAADIKEHLAAKRKRIEK-IAKACSEIKNRIKNVLRTTQLKRQKRDYRISLKLPNV 124
+ + + +E K+K K KA E ++K + +RQKR+ +K
Sbjct: 317 DKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKE-----EEERQKREEEERIKRLEE 371
Query: 125 LEEFITDEQKDEEGDGEKEEQIKIFQEQQKRWQQDGK 161
LE +E++ E+ E+++Q + +E+++R +++GK
Sbjct: 372 LEAKRKEEERLEQEKRERKKQKE--KERKERLKKEGK 406
Score = 31.2 bits (69), Expect = 0.43
Identities = 30/140 (21%), Positives = 57/140 (40%), Gaps = 8/140 (5%)
Query: 21 GKDPVSHEHEERKPVTET-KEGDVT--DEHGERGSFAETDEH-----TGVDTKELEDIAA 72
G P S E E E EGD D+ ++G E ++ + K +++ A
Sbjct: 290 GVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALA 349
Query: 73 DIKEHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQLKRQKRDYRISLKLPNVLEEFITDE 132
+KE +++ E+ K E++ + K R Q KR+++ + + + +E
Sbjct: 350 KLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLT 409
Query: 133 QKDEEGDGEKEEQIKIFQEQ 152
+ E E +K+ Q Q
Sbjct: 410 KSQREARARAEATLKLLQAQ 429
Score = 28.1 bits (61), Expect = 3.6
Identities = 33/149 (22%), Positives = 64/149 (42%), Gaps = 17/149 (11%)
Query: 3 AKDQLEVQVMAAQEMELAGKDPVS-----HEHEERKPVTETKEGDVTDEHGERGSFAETD 57
A+ + ++++ AQ +E+ KD + +E ++RK + + E E E + E
Sbjct: 417 ARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVM 476
Query: 58 EHTGVDTKELEDIAADIKEHLAAKRKRIEKI-AKACSEIKNRIKNVLRTTQLKRQKRDYR 116
E GV KE + +E + ++ A A E +++ ++K
Sbjct: 477 EQ-GVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKEN----- 530
Query: 117 ISLKLPNVLEEFITDEQKDEEGDGEKEEQ 145
P EE +E++DEE + E+EE+
Sbjct: 531 -----PEEEEEEEEEEEEDEESEEEEEEE 554
Score = 26.9 bits (58), Expect = 8.0
Identities = 25/97 (25%), Positives = 43/97 (44%), Gaps = 4/97 (4%)
Query: 4 KDQLEVQVMAAQEMELAGKDPVSHEHEERKPVTETKEGDVTDEHGERGSFAETDEHTGVD 63
K +EV+ +E E ++ E EE + EG DE E+ S E D +D
Sbjct: 522 KVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVS-DEKDSGKTLD 580
Query: 64 TKELEDIAADIKEHLAAKRKRIEKIAKACSEIKNRIK 100
K +++++D + R + E +A + K RI+
Sbjct: 581 KKPSKEMSSDSEYDSDDDRTKEE---RAYDKAKRRIE 614
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 38.1 bits (87), Expect = 0.003
Identities = 36/160 (22%), Positives = 72/160 (45%), Gaps = 15/160 (9%)
Query: 4 KDQLEVQVMAAQEMELAGKDPVSHEHEERKPVTETKEGDVTDEHGERGSFAETDEHTGVD 63
K++ V E+E+ VS +HE+ + E +E D+ S +E+DE
Sbjct: 573 KEEKGVSERENNELEVEESQEVS-DHEDEEEEEEEEEDDIDGGESSDESDSESDEKANYQ 631
Query: 64 TKELEDIAADIK------EHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQLKRQKRDYRI 117
+L +I +I + L +KR++ + K E +++ +R TQL+R +
Sbjct: 632 A-DLANITCEIAIKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQ----- 685
Query: 118 SLKLPNVLEEFITDEQKDEEGDGEKEEQIKIFQEQQKRWQ 157
L N+ E+K ++ E E++++ ++ +R Q
Sbjct: 686 --VLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQRLQ 723
Score = 26.9 bits (58), Expect = 8.0
Identities = 24/94 (25%), Positives = 41/94 (43%), Gaps = 9/94 (9%)
Query: 52 SFAETDEHTGVDTKELEDIAADIKEHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQLKRQ 111
+F+ T + +T E+ D+A E L K KR +K + T + +
Sbjct: 522 TFSPTILSSDKETIEIIDLAKKDLEKLKRKEKRKKKSVAGKED---------NTDTDQEK 572
Query: 112 KRDYRISLKLPNVLEEFITDEQKDEEGDGEKEEQ 145
K + +S + N LE + E D E + E+EE+
Sbjct: 573 KEEKGVSERENNELEVEESQEVSDHEDEEEEEEE 606
>gi|42476169 Paf1, RNA polymerase II associated factor, homolog
[Homo sapiens]
Length = 531
Score = 37.7 bits (86), Expect = 0.005
Identities = 22/68 (32%), Positives = 38/68 (55%), Gaps = 6/68 (8%)
Query: 5 DQLEVQVMAAQEMELAGKDPVSHEHEERKPVTETKEGDVTDEHGERGSFAE----TDEHT 60
++ E++ A++ +L +P E EE + TE KE +DE E+GS +E DEH+
Sbjct: 357 NEKELEAQEARKAQLENHEPEEEEEEEME--TEEKEAGGSDEEQEKGSSSEKEGSEDEHS 414
Query: 61 GVDTKELE 68
G +++ E
Sbjct: 415 GSESEREE 422
>gi|22748943 hypothetical protein LOC145483 [Homo sapiens]
Length = 647
Score = 37.0 bits (84), Expect = 0.008
Identities = 32/110 (29%), Positives = 54/110 (49%), Gaps = 12/110 (10%)
Query: 65 KELEDI-AADIKEHLAAKRKRIEKIAKACSEIKNRIKN-------VLRTTQLKRQKRDYR 116
K LE++ A +KE+ RKR ++ K E+K RI+ V + K ++ Y
Sbjct: 508 KSLEEVFKAKLKENRNNDRKRAKEYKKELEEMKQRIQTRPYLFEQVAKDLAKKEAEQWYL 567
Query: 117 ISLKLPNVLEEFITDEQKDEEGDGEKEEQIKIFQEQQKRWQQDGKGTERD 166
+LK + E+F+ ++ + EKE +IK F R+Q+ K + RD
Sbjct: 568 DTLKQAGLEEDFVRNKGQGTRAVQEKETKIKDF----PRFQETTKLSIRD 613
>gi|4505835 polycystin 2 [Homo sapiens]
Length = 968
Score = 36.6 bits (83), Expect = 0.010
Identities = 27/172 (15%), Positives = 76/172 (44%), Gaps = 16/172 (9%)
Query: 8 EVQVMAAQEMELAGKDPVSHEHEERKPVTETKEGDVTDEHGER--------------GSF 53
E++ + + + ++ HEH++ + E + D+ +H S
Sbjct: 754 EIEAIFTKYDQDGDQELTEHEHQQMRDDLEKEREDLDLDHSSLPRPMSSRSFPRSLDDSE 813
Query: 54 AETDEHTGVDTKELEDIAADIK-EHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQLKRQK 112
+ DE +G ++ I++ + E +R++++ + I ++I V+ ++ +
Sbjct: 814 EDDDEDSGHSSRRRGSISSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERA 873
Query: 113 RDYRISLKLPNVLEEFITDEQKDEEGDGEKEEQIKIFQEQQKRWQQDGKGTE 164
+ R + L +L+ DE+ + + +E+ ++ +E+ +RW+ D ++
Sbjct: 874 KLKRREV-LGRLLDGVAEDERLGRDSEIHREQMERLVREELERWESDDAASQ 924
>gi|190341068 forkhead-associated (FHA) phosphopeptide binding
domain 1 [Homo sapiens]
Length = 1412
Score = 36.2 bits (82), Expect = 0.013
Identities = 37/145 (25%), Positives = 62/145 (42%), Gaps = 18/145 (12%)
Query: 28 EHEERKPVTETKEGDVTDEH---GERGSFAETDEHTGVDTKELEDIAADIKEHLAAKRKR 84
E + + T+ +EG E ER ET E +ELE + A K+ LA
Sbjct: 673 EAQSQNQATDGREGGKALEEYITQERNRAKETLEEERKRMQELESLLAQQKKALA----- 727
Query: 85 IEKIAKACSEIKNRIKNVLRTTQLKRQKRDYRISLKLPNVLEEFITDEQKDE----EGDG 140
K+ ++ KNR+K L Q + Q+ + R++ + VLE I E++ E +
Sbjct: 728 -----KSITQEKNRVKEALEEEQTRVQELEERLA-RQKEVLESSIAHEKRKAKEALESEK 781
Query: 141 EKEEQIKIFQEQQKRWQQDGKGTER 165
K + ++ QQK + E+
Sbjct: 782 RKVQDLENHLTQQKEISESNIAYEK 806
Score = 32.3 bits (72), Expect = 0.19
Identities = 36/152 (23%), Positives = 67/152 (44%), Gaps = 22/152 (14%)
Query: 4 KDQLEVQVMAAQEME--LAGKDPV-----SHEHEERKPVTETKEGDVTDEHGERGSFAET 56
K+ LE + QE+E LA + V +HE + K E+++ V D
Sbjct: 738 KEALEEEQTRVQELEERLARQKEVLESSIAHEKRKAKEALESEKRKVQD----------L 787
Query: 57 DEHTGVDTKELEDIAADIKEHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQLKRQKRDYR 116
+ H T++ E ++I ++ +EK K +++NR+ +LK QK D
Sbjct: 788 ENHL---TQQKEISESNIAYEKRKAKEAMEKEKKKVQDLENRLTKQKEELELKEQKEDV- 843
Query: 117 ISLKLPNVLEEFITDEQKDEEGDGEKEEQIKI 148
++ KL + L + + QK + + K E + +
Sbjct: 844 LNNKLSDAL-AMVEETQKTKATESLKAESLAL 874
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 36.2 bits (82), Expect = 0.013
Identities = 35/161 (21%), Positives = 64/161 (39%), Gaps = 19/161 (11%)
Query: 19 LAGKDPVSHEHEERKPVTETKEGDVTD--EHGERGSFAETDEHTGVDTKELEDIAADIKE 76
L ++ V EE+K E K + + E + AE K++E++ A K+
Sbjct: 582 LQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQ 641
Query: 77 HLAAKRKRI-----------EKIAKACSEIKNRIKNVLRTTQLKRQKRDYRISLKLPNVL 125
A+R R E + K E + R++ +L Q+ R
Sbjct: 642 EEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQER------REQ 695
Query: 126 EEFITDEQKDEEGDGEKEEQIKIFQEQQKRWQQDGKGTERD 166
E + ++ E + E+ EQ + EQ++R +Q+ ER+
Sbjct: 696 ERREQERREQERREQERREQERQLAEQERRREQERLQAERE 736
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 36.2 bits (82), Expect = 0.013
Identities = 35/161 (21%), Positives = 64/161 (39%), Gaps = 19/161 (11%)
Query: 19 LAGKDPVSHEHEERKPVTETKEGDVTD--EHGERGSFAETDEHTGVDTKELEDIAADIKE 76
L ++ V EE+K E K + + E + AE K++E++ A K+
Sbjct: 578 LQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQ 637
Query: 77 HLAAKRKRI-----------EKIAKACSEIKNRIKNVLRTTQLKRQKRDYRISLKLPNVL 125
A+R R E + K E + R++ +L Q+ R
Sbjct: 638 EEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQER------REQ 691
Query: 126 EEFITDEQKDEEGDGEKEEQIKIFQEQQKRWQQDGKGTERD 166
E + ++ E + E+ EQ + EQ++R +Q+ ER+
Sbjct: 692 ERREQERREQERREQERREQERQLAEQERRREQERLQAERE 732
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 35.0 bits (79), Expect = 0.029
Identities = 32/151 (21%), Positives = 71/151 (47%), Gaps = 8/151 (5%)
Query: 15 QEMELAGKDPVSHEHEE-----RKPVTETKEGDVTDEHGERGSFAETDEHT--GVDTKEL 67
Q+ +D V E EE R+ V +E + +E +R + +E ++ +EL
Sbjct: 227 QQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQEL 286
Query: 68 EDIAADIKEHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQLKRQKRDYRISLKLPNVLEE 127
+ +E + +R +++ + E + + R Q +R++++ R +L EE
Sbjct: 287 RRERQE-EEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEE 345
Query: 128 FITDEQKDEEGDGEKEEQIKIFQEQQKRWQQ 158
+ + E+ + +E+Q++ QE+++R QQ
Sbjct: 346 RREQQLRREQEEERREQQLRREQEEERREQQ 376
Score = 33.9 bits (76), Expect = 0.066
Identities = 31/159 (19%), Positives = 74/159 (46%), Gaps = 8/159 (5%)
Query: 6 QLEVQVMAAQEMELAGKDPVSHEHEERKPVTETKEGDVTDEHGERGSFAETDEHTGVDTK 65
Q E + + +E E + + ++ + + + + +E + +E +R + E + +
Sbjct: 1057 QQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRR--QERERQCREEE 1114
Query: 66 ELEDIAADIKEHLAAKRKR--IEKIAKACSEIKNRIKNVLRTTQLKRQK----RDYRISL 119
EL+ + KR+R +E+ + E++ + +LR KR++ R YR
Sbjct: 1115 ELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEE 1174
Query: 120 KLPNVLEEFITDEQKDEEGDGEKEEQIKIFQEQQKRWQQ 158
+L E+ + +EQ+ + E++ + + ++QKR Q+
Sbjct: 1175 ELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQR 1213
Score = 30.0 bits (66), Expect = 0.95
Identities = 35/167 (20%), Positives = 78/167 (46%), Gaps = 12/167 (7%)
Query: 8 EVQVMAAQEMELAGKDPVSHEHEERKPVTETK-EGDVTDEHGERGSFAETDEHTGVDTKE 66
E Q+ QE E + E +ER+ E + E + E ER E + +
Sbjct: 303 EQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQE--EERR 360
Query: 67 LEDIAADIKEHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQLKRQ---KRDYRISLKLPN 123
+ + + +E ++ R E+ + +++ R + + R QL+R+ +R+ ++ +
Sbjct: 361 EQQLRREQEEERREQQLRREQQLRREQQLR-REQQLRREQQLRREQQLRREQQLRREQQL 419
Query: 124 VLEEFITDEQKDEEGDGE-----KEEQIKIFQEQQKRWQQDGKGTER 165
E+ + EQ++E + + +E+++K QE+++ W + + TER
Sbjct: 420 RREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETER 466
Score = 29.6 bits (65), Expect = 1.2
Identities = 27/100 (27%), Positives = 50/100 (50%), Gaps = 8/100 (8%)
Query: 65 KELEDIAADIKEHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQLKRQKRD--YRISLKLP 122
+E E + + ++ +++R KI + + +++ QL+RQ+RD +R +L
Sbjct: 1726 REEEQLRQETEQEQLRRQERYRKILE-----EEQLRPEREEQQLRRQERDRKFREEEQLR 1780
Query: 123 NVLEEFITDEQKDEEGDGEKEEQIKIFQEQQKRWQQ-DGK 161
EE Q+ + E+E+ + +EQQ R QQ DGK
Sbjct: 1781 QEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGK 1820
Score = 28.9 bits (63), Expect = 2.1
Identities = 30/150 (20%), Positives = 67/150 (44%), Gaps = 4/150 (2%)
Query: 11 VMAAQEMELAGKDPVSHEH--EERKPVTETKEGDVTDEHGERGSFAETDEHTGVDTKELE 68
V+ +E +L ++P EE + + + + ++ E E + ++ E
Sbjct: 252 VLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQE 311
Query: 69 DIAADIKEHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQLKRQKRDYRISLKLPNVLEEF 128
+ + +E +++R E+ + + R + R QL+R++ + R +L EE
Sbjct: 312 EERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEE 371
Query: 129 ITDEQKDEEGDGEKEEQIKIFQEQQKRWQQ 158
++Q E +E+Q++ +EQQ R +Q
Sbjct: 372 RREQQLRREQQLRREQQLR--REQQLRREQ 399
Score = 28.5 bits (62), Expect = 2.8
Identities = 34/167 (20%), Positives = 78/167 (46%), Gaps = 16/167 (9%)
Query: 4 KDQLEVQVMAAQEMELAGKDPVSHEHEERKPVTETKEGDVTDEHGERGSFAETDEHTGVD 63
+++ Q + QE E + + E + R+ E +E + E +R ++ +
Sbjct: 511 QEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKRE 570
Query: 64 TKELEDIAADIKEHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQLKR----QKRDYRISL 119
+E D +K +++R+++ E + R++ L+ +++R ++R+ R+
Sbjct: 571 QEERRDQL--LKREEERRQQRLKR------EQEERLEQRLKREEVERLEQEERREQRLKR 622
Query: 120 KLPNVLEEFITDEQKDEEGDGEKEEQIKIFQEQQKRWQQDGKGTERD 166
+ P EE K EE + +++Q++ +EQQ+R +Q K E +
Sbjct: 623 EEPE--EERRQQLLKSEEQEERRQQQLR--REQQERREQRLKREEEE 665
Score = 28.1 bits (61), Expect = 3.6
Identities = 31/155 (20%), Positives = 64/155 (41%), Gaps = 7/155 (4%)
Query: 15 QEMELAGKDPVSHEHEERKPVTETKEGDVTDEHGERGSFAETDEHTGVDTKELEDIAADI 74
+E++ ++ E + + E ++G D+ R D+ +LE+
Sbjct: 829 KELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKW---RWQLEEERKRR 885
Query: 75 KEHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQLKR----QKRDYRISLKLPNVLEEFIT 130
+ L AK E++ K ++ + + R + KR Q+R YR +L E+ +
Sbjct: 886 RHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLR 945
Query: 131 DEQKDEEGDGEKEEQIKIFQEQQKRWQQDGKGTER 165
+E++ + + K + QQK Q G+ E+
Sbjct: 946 EEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEK 980
Score = 26.9 bits (58), Expect = 8.0
Identities = 22/100 (22%), Positives = 49/100 (49%), Gaps = 15/100 (15%)
Query: 75 KEHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQLKRQK----RDYRISLKLPNVLEEFIT 130
+E +R+ E+ + +++ + +LR + KR++ R YR KL E+ +
Sbjct: 916 EEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLG 975
Query: 131 DEQKD-----------EEGDGEKEEQIKIFQEQQKRWQQD 159
+E + EE + ++EE+ + +E++KR +Q+
Sbjct: 976 EEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQE 1015
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 35.0 bits (79), Expect = 0.029
Identities = 32/131 (24%), Positives = 60/131 (45%), Gaps = 9/131 (6%)
Query: 37 ETKEGDVTDEHGER------GSFAETDEHTGVDTKELEDIAADIKEHLAAKRK--RIEKI 88
E E V D+H G AE G T D A + + LA KR+ R++K
Sbjct: 358 EALEKHVVDKHASEKHAAAAGGKAENSAALGKPTAGTTD-AGEAAKILAEKRRQARLQKE 416
Query: 89 AKACSEIKNRIKNVLRTTQLKRQKRDYRISLKLPNVLEEFITDEQKDEEGDGEKEEQIKI 148
+ ++ ++ L +LKR+ + R+ L+ +E Q++E+ E EE+ K
Sbjct: 417 QEEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKA 476
Query: 149 FQEQQKRWQQD 159
+E +++ +++
Sbjct: 477 GEEAKRKAEEE 487
Score = 26.9 bits (58), Expect = 8.0
Identities = 26/137 (18%), Positives = 60/137 (43%), Gaps = 3/137 (2%)
Query: 4 KDQLEVQVMA--AQEMELAGKDPVSHEHEERKPVTETKEGDVTDEHGERGSFAETDEHTG 61
+D+LE + + A+E L ++ + EERK E K+ +E + G A+
Sbjct: 428 QDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAGEEAKRKAEEE 487
Query: 62 VDTKELEDIAADIKEHLAAKRKRIE-KIAKACSEIKNRIKNVLRTTQLKRQKRDYRISLK 120
+ KE ++ K + +++ E K + +++ + ++ + +R +R RI
Sbjct: 488 LLLKEKQEQEKQEKAMIEKQKEAAETKAREVAEQMRLEREQIMLQIEQERLERKKRIDEI 547
Query: 121 LPNVLEEFITDEQKDEE 137
+ + + + K E+
Sbjct: 548 MKRTRKSDVPPQVKKED 564
>gi|5803203 troponin T3, skeletal, fast isoform 1 [Homo sapiens]
Length = 258
Score = 34.7 bits (78), Expect = 0.038
Identities = 35/153 (22%), Positives = 64/153 (41%), Gaps = 32/153 (20%)
Query: 14 AQEMELAGKDPVSHEHEERKPVTETKEGDVTDEHGERGSFAETDEHTGVDTKELEDIAAD 73
AQE E +D + EE KP + + + GE+ F + + K+L ++ A
Sbjct: 19 AQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPE--GEKVDFDDIQKKR--QNKDLMELQAL 74
Query: 74 IKEHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQLKRQKRDYRISLKLPNVLEEFITDEQ 133
I H A++K E++ +K RI+ +R +R EQ
Sbjct: 75 IDSHFEARKKEEEELVA----LKERIEK-------RRAERA-----------------EQ 106
Query: 134 KDEEGDGEKEEQIKIFQEQQKRWQQDGKGTERD 166
+ + E+E Q ++ +E+ +R ++D K D
Sbjct: 107 QRIRAEKERERQNRLAEEKARREEEDAKRRAED 139
>gi|5454014 tripartite motif-containing 38 [Homo sapiens]
Length = 465
Score = 34.7 bits (78), Expect = 0.038
Identities = 31/123 (25%), Positives = 54/123 (43%), Gaps = 16/123 (13%)
Query: 37 ETKEGDVTDEHGERGSFAETDE-------------HTGVDTKELEDIAADIKEHLAAKRK 83
ET + +EHGE+ DE H G T +ED+ KE L
Sbjct: 86 ETDQEMSCEEHGEQFHLFCEDEGQLICWRCERAPQHKGHTTALVEDVCQGYKEKLQKAVT 145
Query: 84 RIEKIAKACSEIKNRIKNVLRTTQLKRQKRDYRISLKLP-NVLEEFITDEQKDEEGDGEK 142
+++++ C+E ++ +R T+ K + + R ++ L+ F+ +E+K EK
Sbjct: 146 KLKQLEDRCTE--QKLSTAMRITKWKEKVQIQRQKIRSDFKNLQCFLHEEEKSYLWRLEK 203
Query: 143 EEQ 145
EEQ
Sbjct: 204 EEQ 206
>gi|27894339 keratin 23 [Homo sapiens]
Length = 422
Score = 34.3 bits (77), Expect = 0.050
Identities = 29/116 (25%), Positives = 60/116 (51%), Gaps = 12/116 (10%)
Query: 30 EERKPVT-ETKEGDVTDEHGERGSFA--ETDEHTGVDTKE-LEDIAADIKEHLAAKRKRI 85
E P T ++++GD+ H + +F E D T TK LE++ ++ + + K + +
Sbjct: 273 EAASPATVQSRQGDI---HELKRTFQALEIDLQTQYSTKSALENMLSETQSRYSCKLQDM 329
Query: 86 EKIAKACSEIKNRIKNVLRTTQLKRQKRDYRISLKLPNVLEEFITDEQKDEEGDGE 141
++I E ++++ +L+RQ +Y++ L + LE+ IT ++ EG+ E
Sbjct: 330 QEIISHYEEELTQLRH-----ELERQNNEYQVLLGIKTHLEKEITTYRRLLEGESE 380
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 34.3 bits (77), Expect = 0.050
Identities = 34/165 (20%), Positives = 75/165 (45%), Gaps = 15/165 (9%)
Query: 4 KDQLEVQVMAAQEMELAGKDPVSHEHEERKPVTETKEGDVTDEHGERGSFAETDEHTGVD 63
+++ + M QE ++ +D E EE E K E +E
Sbjct: 400 QEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEK-------------IRELEEMMQDQ 446
Query: 64 TKELEDIAADIKEHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQL-KRQKRDYRISLKLP 122
++L ++ ++E +++ EKI + +I+ + + R +L K++++ + K+
Sbjct: 447 EEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMW 506
Query: 123 NVLEEFITDEQKDEEGDGEKEEQIKIFQEQQKR-WQQDGKGTERD 166
E+ E+K +E + + + Q + +EQ+ R WQQ+ K E++
Sbjct: 507 RQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQE 551
Score = 31.6 bits (70), Expect = 0.33
Identities = 28/155 (18%), Positives = 71/155 (45%), Gaps = 7/155 (4%)
Query: 12 MAAQEMELAGKDPVSHEHEERKPVTETKEGDVTDEHGERGSFAETDEHTGVDTKELEDIA 71
M QE ++ +D E EE E K + ++ E+ E +E ++
Sbjct: 369 MWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKK------MREQDEKI 422
Query: 72 ADIKEHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQLKRQKRDYRISLKLPNVLEEFITD 131
+ +E + + ++I ++ + + + +++ V Q + +K + K+ E+
Sbjct: 423 REQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEE-KIQRQEEKIQEQ 481
Query: 132 EQKDEEGDGEKEEQIKIFQEQQKRWQQDGKGTERD 166
E+K + +++ KI+++++K W+Q+ K E++
Sbjct: 482 EEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQE 516
Score = 30.8 bits (68), Expect = 0.56
Identities = 28/143 (19%), Positives = 65/143 (45%), Gaps = 8/143 (5%)
Query: 30 EERKPVTETKEGDVTDEHGERGSFAETDEHTGVDTKELEDIAADIKEHLAAKRKRIE--- 86
E P E +TDE + + AE E + E +I ++K+ L K +R +
Sbjct: 198 ERDAPSLELYRNTITDEELKEKN-AELQEKLRLVESEKSEIQLNVKD-LKRKLERAQLLL 255
Query: 87 ---KIAKACSEIKNRIKNVLRTTQLKRQKRDYRISLKLPNVLEEFITDEQKDEEGDGEKE 143
++ + +++V Q + ++ + L + + +E+ E+ + E
Sbjct: 256 PQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCE 315
Query: 144 EQIKIFQEQQKRWQQDGKGTERD 166
+++KI ++++K W+Q+ K E++
Sbjct: 316 QELKIREQEEKMWRQEEKMHEQE 338
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 34.3 bits (77), Expect = 0.050
Identities = 34/165 (20%), Positives = 75/165 (45%), Gaps = 15/165 (9%)
Query: 4 KDQLEVQVMAAQEMELAGKDPVSHEHEERKPVTETKEGDVTDEHGERGSFAETDEHTGVD 63
+++ + M QE ++ +D E EE E K E +E
Sbjct: 400 QEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEK-------------IRELEEMMQDQ 446
Query: 64 TKELEDIAADIKEHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQL-KRQKRDYRISLKLP 122
++L ++ ++E +++ EKI + +I+ + + R +L K++++ + K+
Sbjct: 447 EEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMW 506
Query: 123 NVLEEFITDEQKDEEGDGEKEEQIKIFQEQQKR-WQQDGKGTERD 166
E+ E+K +E + + + Q + +EQ+ R WQQ+ K E++
Sbjct: 507 RQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQE 551
Score = 31.6 bits (70), Expect = 0.33
Identities = 28/155 (18%), Positives = 71/155 (45%), Gaps = 7/155 (4%)
Query: 12 MAAQEMELAGKDPVSHEHEERKPVTETKEGDVTDEHGERGSFAETDEHTGVDTKELEDIA 71
M QE ++ +D E EE E K + ++ E+ E +E ++
Sbjct: 369 MWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKK------MREQDEKI 422
Query: 72 ADIKEHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQLKRQKRDYRISLKLPNVLEEFITD 131
+ +E + + ++I ++ + + + +++ V Q + +K + K+ E+
Sbjct: 423 REQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEE-KIQRQEEKIQEQ 481
Query: 132 EQKDEEGDGEKEEQIKIFQEQQKRWQQDGKGTERD 166
E+K + +++ KI+++++K W+Q+ K E++
Sbjct: 482 EEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQE 516
Score = 28.5 bits (62), Expect = 2.8
Identities = 26/128 (20%), Positives = 60/128 (46%), Gaps = 23/128 (17%)
Query: 62 VDTKELEDIAADIKEHLAAKRKRIEKIAKACSEIKNRIKN---VLRTTQLKRQ-----KR 113
+ +EL++ A+++E L +I ++K +++ +L QL+ + K
Sbjct: 211 ITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKE 270
Query: 114 DYRISLKLPNVLEE---------------FITDEQKDEEGDGEKEEQIKIFQEQQKRWQQ 158
+S KL +EE + +E+ E+ + E+++KI ++++K W+Q
Sbjct: 271 LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQ 330
Query: 159 DGKGTERD 166
+ K E++
Sbjct: 331 EEKMHEQE 338
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 34.3 bits (77), Expect = 0.050
Identities = 39/151 (25%), Positives = 71/151 (47%), Gaps = 16/151 (10%)
Query: 15 QEMELAGKDPVSHEHEERKPVTETKEGDVTDEHGERGSFAETDEHTGVDTKELEDIAADI 74
QEME G++ EH E E +EGD +E + G E E V+ + ++
Sbjct: 725 QEMEEGGEE----EHGEG----EEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERK 776
Query: 75 KEHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQLKRQKRDYRISLKLPNVLEEFITDEQK 134
KE A K ++ E E ++ + T+ + ++++ ++ V E E++
Sbjct: 777 KEERAGKEEKGE-------EEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEE 829
Query: 135 DEEGDGEKEEQIKIFQEQQKRWQQ-DGKGTE 164
+EEG+GE+EE +E + ++ +GKG E
Sbjct: 830 EEEGEGEEEEGEGEEEEGEGEEEEGEGKGEE 860
Score = 28.5 bits (62), Expect = 2.8
Identities = 34/184 (18%), Positives = 71/184 (38%), Gaps = 52/184 (28%)
Query: 28 EHEERKPVTETKEGDVTDEHGERGSF------------------------AETDEHTGVD 63
+ +E + ++E KEG +H +G F AE + G++
Sbjct: 543 DSDEYEEMSEMKEGKACKQHVSQGIFMTQPATTIEAFSDEEVEIPEEKEGAEDSKGNGIE 602
Query: 64 TKELEDIAADIKEHLAAKRK-----------------RIEKIAKA-----------CSEI 95
+E+E ++K H K K + + + +A C E
Sbjct: 603 EQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEG 662
Query: 96 KNRIKNVLRTTQLKRQKRDYRISLKLPNVLEEFITDEQKDEEGDGEKEEQIKIFQEQQKR 155
+ ++ + K +K R ++ P E+ + ++++ ++ DGE++EQ + Q QK
Sbjct: 663 SSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKE 722
Query: 156 WQQD 159
Q+
Sbjct: 723 RNQE 726
>gi|224591408 SH2 domain containing 4B isoform 2 [Homo sapiens]
Length = 309
Score = 33.9 bits (76), Expect = 0.066
Identities = 27/103 (26%), Positives = 53/103 (51%), Gaps = 8/103 (7%)
Query: 61 GVDTKELEDIAADI---KEHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQLKRQKRDYRI 117
G K E+I+ ++ + L A+R+ E + +EI + ++ L + + +++
Sbjct: 37 GPGDKPYEEISEELIAERARLQAQREAEELWRQKEAEITKKFRDALANEKARILAEKWKV 96
Query: 118 SL---KLPNVLEEFITDE--QKDEEGDGEKEEQIKIFQEQQKR 155
+ K VLEE I +E +K+EE EEQI++ +EQ+ +
Sbjct: 97 EMEDRKAAKVLEERIHEEFKRKEEEERKRGEEQIRLQEEQRAK 139
>gi|224591406 SH2 domain containing 4B isoform 1 [Homo sapiens]
Length = 357
Score = 33.9 bits (76), Expect = 0.066
Identities = 27/103 (26%), Positives = 53/103 (51%), Gaps = 8/103 (7%)
Query: 61 GVDTKELEDIAADI---KEHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQLKRQKRDYRI 117
G K E+I+ ++ + L A+R+ E + +EI + ++ L + + +++
Sbjct: 86 GPGDKPYEEISEELIAERARLQAQREAEELWRQKEAEITKKFRDALANEKARILAEKWKV 145
Query: 118 SL---KLPNVLEEFITDE--QKDEEGDGEKEEQIKIFQEQQKR 155
+ K VLEE I +E +K+EE EEQI++ +EQ+ +
Sbjct: 146 EMEDRKAAKVLEERIHEEFKRKEEEERKRGEEQIRLQEEQRAK 188
>gi|195546919 growth arrest-specific 7 isoform d [Homo sapiens]
Length = 412
Score = 33.5 bits (75), Expect = 0.086
Identities = 23/98 (23%), Positives = 48/98 (48%), Gaps = 12/98 (12%)
Query: 63 DTKELEDIAADIKEHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQLKRQKRDYRISLKLP 122
D K+ + AD+++ LA++ +EK KA +E + R ++K Q ++ +KL
Sbjct: 250 DMKKCDHHIADLRKQLASRYASVEKARKALTERQ-------RDLEMKTQ----QLEIKLS 298
Query: 123 NVLEEFITD-EQKDEEGDGEKEEQIKIFQEQQKRWQQD 159
N EE I +K + + + ++ + Q +W ++
Sbjct: 299 NKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEE 336
>gi|41406080 growth arrest-specific 7 isoform c [Homo sapiens]
Length = 476
Score = 33.5 bits (75), Expect = 0.086
Identities = 23/98 (23%), Positives = 48/98 (48%), Gaps = 12/98 (12%)
Query: 63 DTKELEDIAADIKEHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQLKRQKRDYRISLKLP 122
D K+ + AD+++ LA++ +EK KA +E + R ++K Q ++ +KL
Sbjct: 314 DMKKCDHHIADLRKQLASRYASVEKARKALTERQ-------RDLEMKTQ----QLEIKLS 362
Query: 123 NVLEEFITD-EQKDEEGDGEKEEQIKIFQEQQKRWQQD 159
N EE I +K + + + ++ + Q +W ++
Sbjct: 363 NKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEE 400
>gi|41406078 growth arrest-specific 7 isoform b [Homo sapiens]
Length = 416
Score = 33.5 bits (75), Expect = 0.086
Identities = 23/98 (23%), Positives = 48/98 (48%), Gaps = 12/98 (12%)
Query: 63 DTKELEDIAADIKEHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQLKRQKRDYRISLKLP 122
D K+ + AD+++ LA++ +EK KA +E + R ++K Q ++ +KL
Sbjct: 254 DMKKCDHHIADLRKQLASRYASVEKARKALTERQ-------RDLEMKTQ----QLEIKLS 302
Query: 123 NVLEEFITD-EQKDEEGDGEKEEQIKIFQEQQKRWQQD 159
N EE I +K + + + ++ + Q +W ++
Sbjct: 303 NKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEE 340
>gi|41406076 growth arrest-specific 7 isoform a [Homo sapiens]
Length = 336
Score = 33.5 bits (75), Expect = 0.086
Identities = 23/98 (23%), Positives = 48/98 (48%), Gaps = 12/98 (12%)
Query: 63 DTKELEDIAADIKEHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQLKRQKRDYRISLKLP 122
D K+ + AD+++ LA++ +EK KA +E + R ++K Q ++ +KL
Sbjct: 174 DMKKCDHHIADLRKQLASRYASVEKARKALTERQ-------RDLEMKTQ----QLEIKLS 222
Query: 123 NVLEEFITD-EQKDEEGDGEKEEQIKIFQEQQKRWQQD 159
N EE I +K + + + ++ + Q +W ++
Sbjct: 223 NKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEE 260
>gi|110347418 structural maintenance of chromosomes 2 [Homo sapiens]
Length = 1197
Score = 33.5 bits (75), Expect = 0.086
Identities = 34/156 (21%), Positives = 72/156 (46%), Gaps = 13/156 (8%)
Query: 4 KDQLEVQV--MAAQEMELAGKDPVSHEHEERKPVTE--TKEGDVTDEHGERGSFAETDEH 59
+D+L ++ + A E ELAG + ++ + K E T+E D+ ++ S+ + E
Sbjct: 685 QDELRIKENELRALEEELAGLKNTAEKYRQLKQQWEMKTEEADLLQTKLQQSSYHKQQEE 744
Query: 60 TGVDTKELEDIAADIKEHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQLKRQKRDYRISL 119
K +E+ +K +RK EK ++N++KN + +R+ +D + L
Sbjct: 745 LDALKKTIEESEETLKNTKEIQRKAEEKY----EVLENKMKNA--EAERERELKDAQKKL 798
Query: 120 KLPNVLEEFITDEQKDEEGDGEKEEQIKIFQEQQKR 155
+ + + K+++ ++ E I + E+ KR
Sbjct: 799 DCAKTKADASSKKMKEKQ---QEVEAITLELEELKR 831
>gi|110347425 structural maintenance of chromosomes 2 [Homo sapiens]
Length = 1197
Score = 33.5 bits (75), Expect = 0.086
Identities = 34/156 (21%), Positives = 72/156 (46%), Gaps = 13/156 (8%)
Query: 4 KDQLEVQV--MAAQEMELAGKDPVSHEHEERKPVTE--TKEGDVTDEHGERGSFAETDEH 59
+D+L ++ + A E ELAG + ++ + K E T+E D+ ++ S+ + E
Sbjct: 685 QDELRIKENELRALEEELAGLKNTAEKYRQLKQQWEMKTEEADLLQTKLQQSSYHKQQEE 744
Query: 60 TGVDTKELEDIAADIKEHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQLKRQKRDYRISL 119
K +E+ +K +RK EK ++N++KN + +R+ +D + L
Sbjct: 745 LDALKKTIEESEETLKNTKEIQRKAEEKY----EVLENKMKNA--EAERERELKDAQKKL 798
Query: 120 KLPNVLEEFITDEQKDEEGDGEKEEQIKIFQEQQKR 155
+ + + K+++ ++ E I + E+ KR
Sbjct: 799 DCAKTKADASSKKMKEKQ---QEVEAITLELEELKR 831
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.127 0.341
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,154,186
Number of Sequences: 37866
Number of extensions: 272011
Number of successful extensions: 2657
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 73
Number of HSP's successfully gapped in prelim test: 280
Number of HSP's that attempted gapping in prelim test: 2114
Number of HSP's gapped (non-prelim): 729
length of query: 166
length of database: 18,247,518
effective HSP length: 95
effective length of query: 71
effective length of database: 14,650,248
effective search space: 1040167608
effective search space used: 1040167608
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.