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Search of human proteins with 27894324
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27894324 interleukin 1 receptor-like 1 isoform 1 precursor
[Homo sapiens]
(556 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27894324 interleukin 1 receptor-like 1 isoform 1 precursor [H... 1134 0.0
gi|27894328 interleukin 1 receptor-like 1 isoform 2 precursor [H... 665 0.0
gi|4504659 interleukin 1 receptor, type I precursor [Homo sapiens] 224 2e-58
gi|28416902 interleukin 1 receptor-like 2 precursor [Homo sapiens] 206 5e-53
gi|11225607 interleukin 1 receptor accessory protein-like 2 [Hom... 179 6e-45
gi|4504655 interleukin 18 receptor 1 precursor [Homo sapiens] 172 7e-43
gi|4504661 interleukin 1 receptor accessory protein isoform 1 [H... 170 4e-42
gi|7657232 interleukin 1 receptor accessory protein-like 1 precu... 162 1e-39
gi|4504657 interleukin 18 receptor accessory protein precursor [... 145 1e-34
gi|27894334 interleukin 1 receptor, type II precursor [Homo sapi... 95 1e-19
gi|4758598 interleukin 1 receptor, type II precursor [Homo sapiens] 95 1e-19
gi|19882209 interleukin 1 receptor accessory protein isoform 2 [... 80 6e-15
gi|205277451 single Ig IL-1R-related molecule [Homo sapiens] 70 5e-12
gi|205277449 single Ig IL-1R-related molecule [Homo sapiens] 70 5e-12
gi|205277445 single Ig IL-1R-related molecule [Homo sapiens] 70 5e-12
gi|13186251 fibroblast growth factor receptor 1 isoform 2 precur... 64 4e-10
gi|13186249 fibroblast growth factor receptor 1 isoform 9 precur... 63 8e-10
gi|105990522 fibroblast growth factor receptor 1 isoform 1 precu... 63 8e-10
gi|19718734 toll-like receptor 2 [Homo sapiens] 55 2e-07
gi|19924149 toll-like receptor 4 precursor [Homo sapiens] 55 2e-07
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 54 5e-07
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 54 5e-07
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 54 5e-07
gi|41350337 toll-like receptor 1 [Homo sapiens] 52 1e-06
gi|118572606 hemicentin 1 [Homo sapiens] 50 7e-06
gi|13186236 fibroblast growth factor receptor 1 isoform 4 precur... 48 2e-05
gi|13186234 fibroblast growth factor receptor 1 isoform 3 precur... 48 2e-05
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 47 4e-05
gi|110431348 deleted in colorectal carcinoma [Homo sapiens] 46 8e-05
gi|62865621 toll-like receptor 10 precursor [Homo sapiens] 46 8e-05
>gi|27894324 interleukin 1 receptor-like 1 isoform 1 precursor [Homo
sapiens]
Length = 556
Score = 1134 bits (2933), Expect = 0.0
Identities = 556/556 (100%), Positives = 556/556 (100%)
Query: 1 MGFWILAILTILMYSTAAKFSKQSWGLENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQ 60
MGFWILAILTILMYSTAAKFSKQSWGLENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQ
Sbjct: 1 MGFWILAILTILMYSTAAKFSKQSWGLENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQ 60
Query: 61 ERNRVFASGQLLKFLPAAVADSGIYTCIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYS 120
ERNRVFASGQLLKFLPAAVADSGIYTCIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYS
Sbjct: 61 ERNRVFASGQLLKFLPAAVADSGIYTCIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYS 120
Query: 121 TVSGSEKNSKIYCPTIDLYNWTAPLEWFKNCQALQGSRYRAHKSFLVIDNVMTEDAGDYT 180
TVSGSEKNSKIYCPTIDLYNWTAPLEWFKNCQALQGSRYRAHKSFLVIDNVMTEDAGDYT
Sbjct: 121 TVSGSEKNSKIYCPTIDLYNWTAPLEWFKNCQALQGSRYRAHKSFLVIDNVMTEDAGDYT 180
Query: 181 CKFIHNENGANYSVTATRSFTVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCSACFG 240
CKFIHNENGANYSVTATRSFTVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCSACFG
Sbjct: 181 CKFIHNENGANYSVTATRSFTVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCSACFG 240
Query: 241 KGTQFLAAVLWQLNGTKITDFGEPRIQQEEGQNQSFSNGLACLDMVLRIADVKEEDLLLQ 300
KGTQFLAAVLWQLNGTKITDFGEPRIQQEEGQNQSFSNGLACLDMVLRIADVKEEDLLLQ
Sbjct: 241 KGTQFLAAVLWQLNGTKITDFGEPRIQQEEGQNQSFSNGLACLDMVLRIADVKEEDLLLQ 300
Query: 301 YDCLALNLHGLRRHTVRLSRKNPIDHHSIYCIIAVCSVFLMLINVLVIILKMFWIEATLL 360
YDCLALNLHGLRRHTVRLSRKNPIDHHSIYCIIAVCSVFLMLINVLVIILKMFWIEATLL
Sbjct: 301 YDCLALNLHGLRRHTVRLSRKNPIDHHSIYCIIAVCSVFLMLINVLVIILKMFWIEATLL 360
Query: 361 WRDIAKPYKTRNDGKLYDAYVVYPRNYKSSTDGASRVEHFVHQILPDVLENKCGYTLCIY 420
WRDIAKPYKTRNDGKLYDAYVVYPRNYKSSTDGASRVEHFVHQILPDVLENKCGYTLCIY
Sbjct: 361 WRDIAKPYKTRNDGKLYDAYVVYPRNYKSSTDGASRVEHFVHQILPDVLENKCGYTLCIY 420
Query: 421 GRDMLPGEDVVTAVETNIRKSRRHIFILTPQITHNKEFAYEQEVALHCALIQNDAKVILI 480
GRDMLPGEDVVTAVETNIRKSRRHIFILTPQITHNKEFAYEQEVALHCALIQNDAKVILI
Sbjct: 421 GRDMLPGEDVVTAVETNIRKSRRHIFILTPQITHNKEFAYEQEVALHCALIQNDAKVILI 480
Query: 481 EMEALSELDMLQAEALQDSLQHLMKVQGTIKWREDHIANKRSLNSKFWKHVRYQMPVPSK 540
EMEALSELDMLQAEALQDSLQHLMKVQGTIKWREDHIANKRSLNSKFWKHVRYQMPVPSK
Sbjct: 481 EMEALSELDMLQAEALQDSLQHLMKVQGTIKWREDHIANKRSLNSKFWKHVRYQMPVPSK 540
Query: 541 IPRKASSLTPLAAQKQ 556
IPRKASSLTPLAAQKQ
Sbjct: 541 IPRKASSLTPLAAQKQ 556
>gi|27894328 interleukin 1 receptor-like 1 isoform 2 precursor [Homo
sapiens]
Length = 328
Score = 665 bits (1715), Expect = 0.0
Identities = 323/323 (100%), Positives = 323/323 (100%)
Query: 1 MGFWILAILTILMYSTAAKFSKQSWGLENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQ 60
MGFWILAILTILMYSTAAKFSKQSWGLENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQ
Sbjct: 1 MGFWILAILTILMYSTAAKFSKQSWGLENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQ 60
Query: 61 ERNRVFASGQLLKFLPAAVADSGIYTCIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYS 120
ERNRVFASGQLLKFLPAAVADSGIYTCIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYS
Sbjct: 61 ERNRVFASGQLLKFLPAAVADSGIYTCIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYS 120
Query: 121 TVSGSEKNSKIYCPTIDLYNWTAPLEWFKNCQALQGSRYRAHKSFLVIDNVMTEDAGDYT 180
TVSGSEKNSKIYCPTIDLYNWTAPLEWFKNCQALQGSRYRAHKSFLVIDNVMTEDAGDYT
Sbjct: 121 TVSGSEKNSKIYCPTIDLYNWTAPLEWFKNCQALQGSRYRAHKSFLVIDNVMTEDAGDYT 180
Query: 181 CKFIHNENGANYSVTATRSFTVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCSACFG 240
CKFIHNENGANYSVTATRSFTVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCSACFG
Sbjct: 181 CKFIHNENGANYSVTATRSFTVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCSACFG 240
Query: 241 KGTQFLAAVLWQLNGTKITDFGEPRIQQEEGQNQSFSNGLACLDMVLRIADVKEEDLLLQ 300
KGTQFLAAVLWQLNGTKITDFGEPRIQQEEGQNQSFSNGLACLDMVLRIADVKEEDLLLQ
Sbjct: 241 KGTQFLAAVLWQLNGTKITDFGEPRIQQEEGQNQSFSNGLACLDMVLRIADVKEEDLLLQ 300
Query: 301 YDCLALNLHGLRRHTVRLSRKNP 323
YDCLALNLHGLRRHTVRLSRKNP
Sbjct: 301 YDCLALNLHGLRRHTVRLSRKNP 323
>gi|4504659 interleukin 1 receptor, type I precursor [Homo sapiens]
Length = 569
Score = 224 bits (570), Expect = 2e-58
Identities = 156/546 (28%), Positives = 265/546 (48%), Gaps = 42/546 (7%)
Query: 29 NEALIVRCP-RQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTC 87
NE + CP + T+ WY + + T++ +R+ + L F+PA V DSG Y C
Sbjct: 37 NEIDVRPCPLNPNEHKGTITWYKDDSKTPVSTEQASRIHQHKEKLWFVPAKVEDSGHYYC 96
Query: 88 IVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCPTIDLY----NWTA 143
+VR+ ++ + + + + ++ + + CP ++ + N
Sbjct: 97 VVRNSSYCLRIKISAKFVENEPNLCYNAQAIFKQKLPVAGDGGLVCPYMEFFKNENNELP 156
Query: 144 PLEWFKNCQAL--QGSRYRAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSVTATRSFT 201
L+W+K+C+ L + K L++ NV + G+YTC + G Y +T F
Sbjct: 157 KLQWYKDCKPLLLDNIHFSGVKDRLIVMNVAEKHRGNYTCHASYTYLGKQYPITRVIEFI 216
Query: 202 VKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQLNGTKITD- 260
+E + PVI +PA NE EV++G L C+ Q W+ NG+ I +
Sbjct: 217 TLEENKPTR-PVIVSPA-NETMEVDLGSQIQLICNVT----GQLSDIAYWKWNGSVIDED 270
Query: 261 ---FGEPRIQQEEGQNQSFSNGLACLDMVLRIADVKEEDLLLQYDCLALNLHGLRRHTVR 317
GE E N+ S L VL I++++ + C A N HG+ ++
Sbjct: 271 DPVLGEDYYSVENPANKRRST----LITVLNISEIESRFYKHPFTCFAKNTHGIDAAYIQ 326
Query: 318 LSRKNPIDHHSIYCIIAVCSVFLMLINVLVIILKMFWIEATLLWRDIAKPYKT--RNDGK 375
L P+ + + +I +C ++I V I K+F I+ L +RD + +DGK
Sbjct: 327 LIY--PVTNFQKH-MIGICVTLTVIIVCSVFIYKIFKIDIVLWYRDSCYDFLPIKASDGK 383
Query: 376 LYDAYVVYPRNYKSSTDGASRVEHFVHQILPDVLENKCGYTLCIYGRDMLPGEDVVTAVE 435
YDAY++YP+ + S + FV ++LP+VLE +CGY L IYGRD GED+V +
Sbjct: 384 TYDAYILYPKTVGEGS--TSDCDIFVFKVLPEVLEKQCGYKLFIYGRDDYVGEDIVEVIN 441
Query: 436 TNIRKSRRHIFILTPQITHNKEFAY-----EQEVALHCALIQNDAKVILIEMEALSELDM 490
N++KSRR I IL + F++ E+++A++ AL+Q+ KV+L+E+E + +
Sbjct: 442 ENVKKSRRLIIIL---VRETSGFSWLGGSSEEQIAMYNALVQDGIKVVLLELEKIQDY-- 496
Query: 491 LQAEALQDSLQHLMKVQGTIKWREDHIANKRSLNSKFWKHVRYQMPVPSKIP-RKASSLT 549
E + +S++ + + G I+W D +S ++FWK+VRY MPV + P K L+
Sbjct: 497 ---EKMPESIKFIKQKHGAIRWSGDFTQGPQSAKTRFWKNVRYHMPVQRRSPSSKHQLLS 553
Query: 550 PLAAQK 555
P +K
Sbjct: 554 PATKEK 559
>gi|28416902 interleukin 1 receptor-like 2 precursor [Homo sapiens]
Length = 575
Score = 206 bits (524), Expect = 5e-53
Identities = 149/520 (28%), Positives = 255/520 (49%), Gaps = 38/520 (7%)
Query: 45 TVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCIVRSPTFNRTGYANVTI 104
+V WY + + + ++R+ + FLP DSG+Y C+++ + N+T+
Sbjct: 53 SVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIHVNLTV 112
Query: 105 YKKQ----SDCNVPDYL-MYSTVSGSEKNSKIYCPTIDLYNWT-APLEWFKNCQALQGSR 158
++K S +P+ Y + K+ + C + P++W+K+C ++G R
Sbjct: 113 FEKHWCDTSIGGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLGPIKWYKDCNEIKGER 172
Query: 159 YRAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSVTATRSFTVKDEQGFS-LFPVIGAP 217
+ ++ L++ NV ED G+Y C+ I +G Y V + ++ + G+ P I P
Sbjct: 173 FTVLETRLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSITERAGYGGSVPKIIYP 232
Query: 218 AQNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQLNGTKITDFGEPRIQQEEGQNQSFS 277
+ I EV++G + C+ K L W++N T + D+ + + EG S
Sbjct: 233 KNHSI-EVQLGTTLIVDCNVTDTKDNTNLRC--WRVNNTLVDDYYDESKRIREGVETHVS 289
Query: 278 NGLACLDMV-LRIADVKEEDLLLQYDCLALNLHGLRRHTVRLSRKNPIDHHSIYCIIAVC 336
L V + +VK ED L + C A G+ T + + P Y I +
Sbjct: 290 FREHNLYTVNITFLEVKMEDYGLPFMCHA----GVS--TAYIILQLPAPDFRAYLIGGLI 343
Query: 337 SVFLMLINVLVIILKMFWIEATLLWRDIAKPYKTRNDGKLYDAYVVYPRNYKSSTDGASR 396
++ + ++V V I +F I+ L +R +T DGKLYDAYV+YP+ +K S A
Sbjct: 344 ALVAVAVSV-VYIYNIFKIDIVLWYRSAFHSTETIVDGKLYDAYVLYPKPHKESQRHA-- 400
Query: 397 VEHFVHQILPDVLENKCGYTLCIYGRDMLPGEDVVTAVETNIRKSRRHIFILTPQ----- 451
V+ V ILP+VLE +CGY L I+GRD PG+ V ++ N++ RR I I+ P+
Sbjct: 401 VDALVLNILPEVLERQCGYKLFIFGRDEFPGQAVANVIDENVKLCRRLIVIVVPESLGFG 460
Query: 452 ITHNKEFAYEQEVALHCALIQNDAKVILIEMEALSELDMLQAEALQDSLQHLMKVQGTIK 511
+ N E+++A++ ALIQ+ KVILIE+E + + + + +S+Q++ + G I+
Sbjct: 461 LLKNLS---EEQIAVYSALIQDGMKVILIELEKIEDYTV-----MPESIQYIKQKHGAIR 512
Query: 512 WREDHIANKRSLNSKFWKHVRYQMPVPSKIPRKASSLTPL 551
W D + + +KFWK VRY MP PR+ P+
Sbjct: 513 WHGDFTEQSQCMKTKFWKTVRYHMP-----PRRCRPFPPV 547
>gi|11225607 interleukin 1 receptor accessory protein-like 2 [Homo
sapiens]
Length = 686
Score = 179 bits (454), Expect = 6e-45
Identities = 140/479 (29%), Positives = 234/479 (48%), Gaps = 24/479 (5%)
Query: 74 FLPAAVADSGIYTCIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYC 133
F A DSG YTC++R+ T+ ++T+ + +S + Y S K +I C
Sbjct: 103 FHSAEAQDSGFYTCVLRNSTYCMKVSMSLTVAENESGLCYNSRIRYLEKSEVTKRKEISC 162
Query: 134 PTIDLYNWT---APLEWFKNCQALQGSRYRAHK-SFLVIDNVMTEDAGDYTCKFIHNENG 189
P +D + + + W+K C+ K + L+I V ED G+YTC+ +
Sbjct: 163 PDMDDFKKSDQEPDVVWYKECKPKMWRSIIIQKGNALLIQEVQEEDGGNYTCELKYEGKL 222
Query: 190 ANYSVTATRSFTVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCSACFGKGTQFLAAV 249
+ + + D+ LFP+ P+ + +V++GK N+ C A FG + +
Sbjct: 223 VRRTTELKVTALLTDKPPKPLFPMENQPS---VIDVQLGKPLNIPCKAFFGFSGESGPMI 279
Query: 250 LWQLNGTKITDFGEPRIQQEEGQNQSFSNGLACLDMVLRIADVKEEDLLLQYDCLALNLH 309
W + G K + I++ E + G +++ L V E DL Y C N +
Sbjct: 280 YW-MKGEKFIEELAGHIREGEIRLLKEHLGEKEVELALIFDSVVEADLA-NYTCHVENRN 337
Query: 310 GLRRHTVRLSRKNPIDHHSIYCIIAVCSVFLMLINVLVIILKMFWIEATLLWRDIAKPYK 369
G + +V L +K+ I + I + ++FL+L+ +LV+I K + IE L +R +
Sbjct: 338 GRKHASVLLRKKDLI--YKIELAGGLGAIFLLLV-LLVVIYKCYNIELMLFYRQHFGADE 394
Query: 370 TRNDGKLYDAYVVYPRNYKSSTDGAS-RVEHFVHQILPDVLENKCGYTLCIYGRDMLPGE 428
T +D K YDAY+ Y + + + D + E F ++LPDVLE GY L I RD++P
Sbjct: 395 TNDDNKEYDAYLSYTKVDQDTLDCDNPEEEQFALEVLPDVLEKHYGYKLFIPERDLIPSG 454
Query: 429 DVVTAVETNIRKSRRHIFILTPQITHNKEFA-YEQEVALHCALIQNDAKVILIE-MEALS 486
+ + + +SRR I +LTP + ++ +E E LH L+ + KVILIE E
Sbjct: 455 TYMEDLTRYVEQSRRLIIVLTPDYILRRGWSIFELESRLHNMLVSGEIKVILIECTELKG 514
Query: 487 ELDMLQAEALQDSLQHLMKVQGTIKWREDHIANKRSLNSKFWKHVRYQMPVPSK--IPR 543
+++ + E+L+ S+ K+ IKW+ + LNSKFWKH+ Y+MP+ K +PR
Sbjct: 515 KVNCQEVESLKRSI----KLLSLIKWKG---SKSSKLNSKFWKHLVYEMPIKKKEMLPR 566
>gi|4504655 interleukin 18 receptor 1 precursor [Homo sapiens]
Length = 541
Score = 172 bits (436), Expect = 7e-43
Identities = 140/505 (27%), Positives = 231/505 (45%), Gaps = 37/505 (7%)
Query: 45 TVDWYYS---QTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCIVRSPTFNRTGYAN 101
T WY S Q + + + +R+ +L+F P + D+G Y ++ N T
Sbjct: 53 TKSWYKSSGSQEHVELNPRSSSRIALHDCVLEFWPVELNDTGSYFFQMK----NYTQKWK 108
Query: 102 VTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCPTIDLYNWTAPLEWFKNCQALQGSRYRA 161
+ + ++ + + S + +K +I C +KNC+ L
Sbjct: 109 LNVIRRNKHSCFTERQVTSKIVEVKKFFQITCENSYYQTLVNSTSLYKNCKKLL---LEN 165
Query: 162 HKSFLVIDNVMTEDAGDYTCKFIHNENGANYSVTATRSFTVKDEQGFSLFPVIGAPAQNE 221
+K+ + N ED G Y+C + NG +++T T + T+ +++ ++ PV+ P N
Sbjct: 166 NKNPTIKKNAEFEDQGYYSCVHFLHHNGKLFNITKTFNITIVEDRS-NIVPVLLGPKLNH 224
Query: 222 IKEVEIGKNANLTCSACFGKGTQFLAAVLWQLNGTKITDFGEPRIQQEEGQNQSFSNGLA 281
+ VE+GKN L CSA + + W +D P I +E+ G
Sbjct: 225 VA-VELGKNVRLNCSALLNEED----VIYWMFGEENGSD---PNIHEEKEMRIMTPEGKW 276
Query: 282 CLDMVLRIADVKEEDLLLQYDCLALNLHGLRRHTVRLSRKNP---IDHHSIYCIIAVCSV 338
VLRI ++ E +L + Y+C + G + L RK I H + + +
Sbjct: 277 HASKVLRIENIGESNLNVLYNCTVASTGGTDTKSFILVRKADMADIPGHVFTRGMIIAVL 336
Query: 339 FLMLINVLVIILKMFWIEATLLWRDIAKPYKTRNDGKLYDAYVVYPRNYKSSTDGASRVE 398
L+ + LV + ++ ++ L +R + + +T DGK YDA+V Y + + E
Sbjct: 337 ILVAVVCLVTVCVIYRVDLVLFYRHLTRRDETLTDGKTYDAFVSYLKECRPENGE----E 392
Query: 399 H-FVHQILPDVLENKCGYTLCIYGRDMLPGEDVVTAVETNIRKSRRHIFILTPQITHNKE 457
H F +ILP VLE GY LCI+ RD++PG VV + + I KSRR I +L+ N E
Sbjct: 393 HTFAVEILPRVLEKHFGYKLCIFERDVVPGGAVVDEIHSLIEKSRRLIIVLSKSYMSN-E 451
Query: 458 FAYEQEVALHCALIQNDAKVILIEMEALSELDMLQAEALQDSLQHLMKVQGTIKWREDHI 517
YE E LH AL++ K+ILIE +++ L SL+ L+K +KW+ D
Sbjct: 452 VRYELESGLHEALVERKIKIILIEFTPVTDFTF-----LPQSLK-LLKSHRVLKWKAD-- 503
Query: 518 ANKRSLNSKFWKHVRYQMPVPSKIP 542
S NS+FWK++ Y MP + P
Sbjct: 504 -KSLSYNSRFWKNLLYLMPAKTVKP 527
>gi|4504661 interleukin 1 receptor accessory protein isoform 1 [Homo
sapiens]
Length = 570
Score = 170 bits (430), Expect = 4e-42
Identities = 139/519 (26%), Positives = 235/519 (45%), Gaps = 44/519 (8%)
Query: 45 TVDWYYSQTNKSI--PTQER---NRVFASGQLLKFLPAAVADSGIYTCIVRSPTFNRTGY 99
T+ WY+++ ++ + P R NR+ +L F P + D+G YTC++R+ T+
Sbjct: 67 TLIWYWTRQDRDLEEPINFRLPENRISKEKDVLWFRPTLLNDTGNYTCMLRNTTYCSKVA 126
Query: 100 ANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCPTIDLY---NWTAPLEWFKNCQALQG 156
+ + +K S N P L + +I CP +D Y + + W+ C +Q
Sbjct: 127 FPLEVVQKDSCFNSPMKLPVHKLYIEYGIQRITCPNVDGYFPSSVKPTITWYMGCYKIQN 186
Query: 157 SRY----RAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSVTATRSFTVKDEQGFSLFP 212
+ SFL+ + + G+YTC + ENG + +T T + V ++ P
Sbjct: 187 FNNVIPEGMNLSFLI---ALISNNGNYTCVVTYPENGRTFHLTRTLTVKVVGSPKNAVPP 243
Query: 213 VIGAPAQNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQLNGTKITDFGEPRIQQEEGQ 272
VI +P + + E E G+ + C+ F V W ++G K D I +
Sbjct: 244 VIHSPNDHVVYEKEPGEELLIPCTVYFSFLMDSRNEVWWTIDGKKPDD-----ITIDVTI 298
Query: 273 NQSFSNGLA---CLDMVLRIADVKEEDLLLQYDCLALNLHGLRRHTVRLSRKNPIDHHSI 329
N+S S+ +L I V EDL Y C A + G ++ +K P +++
Sbjct: 299 NESISHSRTEDETRTQILSIKKVTSEDLKRSYVCHARSAKGEVAKAAKVKQKVPAPRYTV 358
Query: 330 YCIIAVCSVFLMLINVLVIILKMFWIEATLLWRDIAKPYKTRNDGKLYDAYVVYPRNYKS 389
+ L+++ +L+++ ++W+E L +R +T DGK YD YV Y RN +
Sbjct: 359 ELACGFGATVLLVV-ILIVVYHVYWLEMVLFYRAHFGTDETILDGKEYDIYVSYARNAEE 417
Query: 390 STDGASRVEHFVHQILPDVLENKCGYTLCIYGRDMLPGEDVVTAVETNIRKSRRHIFILT 449
E FV L VLEN+ GY LCI+ RD LPG V + I+KSRR + +L+
Sbjct: 418 --------EEFVLLTLRGVLENEFGYKLCIFDRDSLPGGIVTDETLSFIQKSRRLLVVLS 469
Query: 450 PQ-ITHNKEFAYEQEVALHCALIQNDAKVILIEMEALSELDMLQAEALQDSLQHLMKVQG 508
P + + E + L + + VIL++ +A+ E + + L+ V
Sbjct: 470 PNYVLQGTQALLELKAGLENMASRGNINVILVQYKAVKETKVKE-------LKRAKTVLT 522
Query: 509 TIKWREDHIANKRSLNSKFWKHVRYQMPVPSKIPRKASS 547
IKW+ + + +FWK ++ MPV K PR++SS
Sbjct: 523 VIKWKGE---KSKYPQGRFWKQLQVAMPV-KKSPRRSSS 557
>gi|7657232 interleukin 1 receptor accessory protein-like 1
precursor [Homo sapiens]
Length = 696
Score = 162 bits (409), Expect = 1e-39
Identities = 131/472 (27%), Positives = 220/472 (46%), Gaps = 25/472 (5%)
Query: 74 FLPAAVADSGIYTCIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYC 133
F P + DSG+Y C++R+ T+ ++T+ + + + Y + K+ +I C
Sbjct: 105 FRPTLLQDSGLYACVIRNSTYCMKVSISLTVGENDTGLCYNSKMKYFEKAELSKSKEISC 164
Query: 134 PTID---LYNWTAPLEWFKNCQALQGSRYRAHK-SFLVIDNVMTEDAGDYTCKFIHNENG 189
I+ L + W+K C+ K L+I V +D G+YTC+ +
Sbjct: 165 RDIEDFLLPTREPEILWYKECRTKTWRPSIVFKRDTLLIREVREDDIGNYTCELKYGGFV 224
Query: 190 ANYSVTATRSFTVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCSACFGKGTQFLAAV 249
+ T + + D+ L+P+ ++ I+E ++G +ANLTC A FG +
Sbjct: 225 VRRTTELTVTAPLTDKPPKLLYPM---ESKLTIQETQLGDSANLTCRAFFGYSGDVSPLI 281
Query: 250 LWQLNGTKITDFGEPRIQQEEGQNQSFSNGLACLDMVLRIADVKEEDLLLQYDCLALNLH 309
W I D E R+ + + + G + + L + V+E DL Y C N +
Sbjct: 282 YWMKGEKFIEDLDENRVWESDIRILKEHLGEQEVSISLIVDSVEEGDLG-NYSCYVENGN 340
Query: 310 GLRRHTVRLSRKNPIDHHSIYCIIAVCSVFLMLINVLVIILKMFWIEATLLWRDIAKPYK 369
G R +V L ++ + +++ + ++ L+L+ LV I K + IE L +R+ +
Sbjct: 341 GRRHASVLLHKRELM--YTVELAGGLGAILLLLV-CLVTIYKCYKIEIMLFYRNHFGAEE 397
Query: 370 TRNDGKLYDAYVVY----PRNYKSSTDGASRVEHFVHQILPDVLENKCGYTLCIYGRDML 425
D K YDAY+ Y P + T E F +ILPD+LE GY L I RD++
Sbjct: 398 LDGDNKDYDAYLSYTKVDPDQWNQET---GEEERFALEILPDMLEKHYGYKLFIPDRDLI 454
Query: 426 PGEDVVTAVETNIRKSRRHIFILTPQITHNKEFA-YEQEVALHCALIQNDAKVILIEMEA 484
P + V + +S+R I ++TP + ++ +E E L L+ + KVILIE
Sbjct: 455 PTGTYIEDVARCVDQSKRLIIVMTPNYVVRRGWSIFELETRLRNMLVTGEIKVILIE--- 511
Query: 485 LSELDMLQAEALQDSLQHLMKVQGTIKWREDHIANKRSLNSKFWKHVRYQMP 536
SEL + ++L+H +K+ IKW H LNSKFWK ++Y+MP
Sbjct: 512 CSELRGIMNYQEVEALKHTIKLLTVIKW---HGPKCNKLNSKFWKRLQYEMP 560
>gi|4504657 interleukin 18 receptor accessory protein precursor
[Homo sapiens]
Length = 599
Score = 145 bits (365), Expect = 1e-34
Identities = 131/511 (25%), Positives = 229/511 (44%), Gaps = 50/511 (9%)
Query: 46 VDWYYSQTNKSIPTQERNR----VFASGQLLKFLPAAVADSGIYTC---IVRSPTFNRTG 98
V WY +N P ++ + + L FL V +SG Y C +++SP
Sbjct: 82 VQWYQQPSNGD-PLEDIRKSYPHIIQDKCTLHFLTPGVNNSGSYICRPKMIKSPYDVACC 140
Query: 99 YANVTIYKKQSDCNVP-------DYLMYSTVSGSEKNSKIYCPTIDLYN--WTAPLEWFK 149
+ K Q++ + D L+ ST S I CP++ + + + W+K
Sbjct: 141 VKMILEVKPQTNASCEYSASHKQDLLLGSTGS-------ISCPSLSCQSDAQSPAVTWYK 193
Query: 150 NCQALQGSRYRAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSVTATRSF-TVKDEQGF 208
N + L R + +V+D V G Y C + ++ ++++V A T+ +
Sbjct: 194 NGKLLSVER----SNRIVVDEVYDYHQGTYVCDYTQSDTVSSWTVRAVVQVRTIVGDT-- 247
Query: 209 SLFPVIGAPAQNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQLNGTKITDFGEPRIQQ 268
L P I P ++ + EVE+GK ++C A FG F + W + + + E + +
Sbjct: 248 KLKPDILDPVEDTL-EVELGKPLTISCKARFGFERVFNPVIKWYIKDSDLE--WEVSVPE 304
Query: 269 EEGQNQSFSNGLACLDMVLRIADVKEEDLLLQYDCLALNLHGLRRHTVRLSRKNPIDHHS 328
+ + + + +++L V + DL ++ C N G +V+L K +
Sbjct: 305 AKSIKSTLKDEIIERNIILE--KVTQRDLRRKFVCFVQNSIGNTTQSVQLKEKRGVV--L 360
Query: 329 IYCIIAVCSVFLMLINVLVIILKMFWIEATLLWRDIAKPYKTRNDGKLYDAYVVYPR--N 386
+Y ++ + ++ ++ + WIE LL+R +T D K +DA+V Y + +
Sbjct: 361 LYILLGTIGTLVAVLAASALLYR-HWIEIVLLYRTYQSKDQTLGDKKDFDAFVSYAKWSS 419
Query: 387 YKSSTDGASRVEHFVHQILPDVLENKCGYTLCIYGRDMLPGEDVVTAVETNIRKSRRHIF 446
+ S + EH + PDVLENK GY+LC+ RD+ PG + + I++SRR IF
Sbjct: 420 FPSEATSSLSEEHLALSLFPDVLENKYGYSLCLLERDVAPGGVYAEDIVSIIKRSRRGIF 479
Query: 447 ILTPQITHNKEFAYEQEVALHCALIQNDAKVILIEMEALSELDMLQAEALQDSLQHLMKV 506
IL+P N +E + A++ AL K+ILI+ E E+L ++ ++V
Sbjct: 480 ILSPNYV-NGPSIFELQAAVNLALDDQTLKLILIKFCYFQE-----PESLPHLVKKALRV 533
Query: 507 QGTIKWREDHIANKRSLNSKFWKHVRYQMPV 537
T+ WR NS+FW +RY MPV
Sbjct: 534 LPTVTWRG---LKSVPPNSRFWAKMRYHMPV 561
>gi|27894334 interleukin 1 receptor, type II precursor [Homo
sapiens]
Length = 398
Score = 95.1 bits (235), Expect = 1e-19
Identities = 82/339 (24%), Positives = 149/339 (43%), Gaps = 28/339 (8%)
Query: 22 KQSWGLENEALIVRCPR-------QGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKF 74
K+ + LE E + +RCP+ P + W+ + + +++P +E R++A L
Sbjct: 36 KREFRLEGEPVALRCPQVPYWLWASVSPRINLTWHKNDSARTVPGEEETRMWAQDGALWL 95
Query: 75 LPAAVADSGIYTCIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCP 134
LPA DSG Y C R+ ++ + ++ + +D +P ++ Y + + + CP
Sbjct: 96 LPALQEDSGTYVCTTRNASYCDKMSIELRVF-ENTDAFLP-FISYPQILTLSTSGVLVCP 153
Query: 135 TIDLYNWT-----APLEWFKNCQALQGSRYR----AHKSFLVIDNVMTEDAGDYTCKFIH 185
DL +T ++W+K+ L + + L++ +V EDAG Y C
Sbjct: 154 --DLSEFTRDKTDVKIQWYKDSLLLDKDNEKFLSVRGTTHLLVHDVALEDAGYYRCVLTF 211
Query: 186 NENGANYSVTATRSFTVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCSACFGKGTQF 245
G Y++T + +K ++ ++ PVI +P + +G + C G GT
Sbjct: 212 AHEGQQYNITRSIELRIKKKKEETI-PVIISPLKT--ISASLGSRLTIPCKVFLGTGTPL 268
Query: 246 LAAVLWQLNGTKITDFGEPRIQQEEGQNQSFS-NGLACLDMVLRIADVKEEDLLLQYDCL 304
+ W N T I + P + EG Q +S N +++ L V EDL + + C+
Sbjct: 269 TTMLWWTANDTHI-ESAYPGGRVTEGPRQEYSENNENYIEVPLIFDPVTREDLHMDFKCV 327
Query: 305 ALNLHGLRRHTVRLSRKNPIDHHSIYCIIAVCSV-FLML 342
N L T+R + K S ++A S+ FL+L
Sbjct: 328 VHNT--LSFQTLRTTVKEASSTFSWGIVLAPLSLAFLVL 364
>gi|4758598 interleukin 1 receptor, type II precursor [Homo sapiens]
Length = 398
Score = 95.1 bits (235), Expect = 1e-19
Identities = 82/339 (24%), Positives = 149/339 (43%), Gaps = 28/339 (8%)
Query: 22 KQSWGLENEALIVRCPR-------QGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKF 74
K+ + LE E + +RCP+ P + W+ + + +++P +E R++A L
Sbjct: 36 KREFRLEGEPVALRCPQVPYWLWASVSPRINLTWHKNDSARTVPGEEETRMWAQDGALWL 95
Query: 75 LPAAVADSGIYTCIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCP 134
LPA DSG Y C R+ ++ + ++ + +D +P ++ Y + + + CP
Sbjct: 96 LPALQEDSGTYVCTTRNASYCDKMSIELRVF-ENTDAFLP-FISYPQILTLSTSGVLVCP 153
Query: 135 TIDLYNWT-----APLEWFKNCQALQGSRYR----AHKSFLVIDNVMTEDAGDYTCKFIH 185
DL +T ++W+K+ L + + L++ +V EDAG Y C
Sbjct: 154 --DLSEFTRDKTDVKIQWYKDSLLLDKDNEKFLSVRGTTHLLVHDVALEDAGYYRCVLTF 211
Query: 186 NENGANYSVTATRSFTVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCSACFGKGTQF 245
G Y++T + +K ++ ++ PVI +P + +G + C G GT
Sbjct: 212 AHEGQQYNITRSIELRIKKKKEETI-PVIISPLKT--ISASLGSRLTIPCKVFLGTGTPL 268
Query: 246 LAAVLWQLNGTKITDFGEPRIQQEEGQNQSFS-NGLACLDMVLRIADVKEEDLLLQYDCL 304
+ W N T I + P + EG Q +S N +++ L V EDL + + C+
Sbjct: 269 TTMLWWTANDTHI-ESAYPGGRVTEGPRQEYSENNENYIEVPLIFDPVTREDLHMDFKCV 327
Query: 305 ALNLHGLRRHTVRLSRKNPIDHHSIYCIIAVCSV-FLML 342
N L T+R + K S ++A S+ FL+L
Sbjct: 328 VHNT--LSFQTLRTTVKEASSTFSWGIVLAPLSLAFLVL 364
>gi|19882209 interleukin 1 receptor accessory protein isoform 2
[Homo sapiens]
Length = 356
Score = 79.7 bits (195), Expect = 6e-15
Identities = 72/292 (24%), Positives = 124/292 (42%), Gaps = 23/292 (7%)
Query: 45 TVDWYYSQTNKSI--PTQER---NRVFASGQLLKFLPAAVADSGIYTCIVRSPTFNRTGY 99
T+ WY+++ ++ + P R NR+ +L F P + D+G YTC++R+ T+
Sbjct: 67 TLIWYWTRQDRDLEEPINFRLPENRISKEKDVLWFRPTLLNDTGNYTCMLRNTTYCSKVA 126
Query: 100 ANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCPTIDLY---NWTAPLEWFKNCQALQG 156
+ + +K S N P L + +I CP +D Y + + W+ C +Q
Sbjct: 127 FPLEVVQKDSCFNSPMKLPVHKLYIEYGIQRITCPNVDGYFPSSVKPTITWYMGCYKIQN 186
Query: 157 SRY----RAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSVTATRSFTVKDEQGFSLFP 212
+ SFL+ + + G+YTC + ENG + +T T + V ++ P
Sbjct: 187 FNNVIPEGMNLSFLI---ALISNNGNYTCVVTYPENGRTFHLTRTLTVKVVGSPKNAVPP 243
Query: 213 VIGAPAQNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQLNGTKITDFGEPRIQQEEGQ 272
VI +P + + E E G+ + C+ F V W ++G K D I +
Sbjct: 244 VIHSPNDHVVYEKEPGEELLIPCTVYFSFLMDSRNEVWWTIDGKKPDD-----ITIDVTI 298
Query: 273 NQSFSNGLA---CLDMVLRIADVKEEDLLLQYDCLALNLHGLRRHTVRLSRK 321
N+S S+ +L I V EDL Y C A + G ++ +K
Sbjct: 299 NESISHSRTEDETRTQILSIKKVTSEDLKRSYVCHARSAKGEVAKAAKVKQK 350
>gi|205277451 single Ig IL-1R-related molecule [Homo sapiens]
Length = 410
Score = 70.1 bits (170), Expect = 5e-12
Identities = 75/323 (23%), Positives = 128/323 (39%), Gaps = 29/323 (8%)
Query: 216 APAQNEIKEVEIGKNANLTCSACFGKGTQF-LAAVLWQLNGTKITDFGEPRIQQEEGQNQ 274
+P+++++ +G + L C+A G L +V W +G + G + +
Sbjct: 13 SPSEDQVLRPALGSSVALNCTAWVVSGPHCSLPSVQWLKDGLPLGIGGHYSLHEYSWVKA 72
Query: 275 SFSNGLACLDMVLRIADVKEEDLLLQYDCLALNLHGLRRHTVRLSRKNPIDHHSIYCIIA 334
+ S L + + + + Y ++ + + L R P H + A
Sbjct: 73 NLSEVLVSSVLGVNVTSTEV------YGAFTCSIQNISFSSFTLQRAGPTSH-----VAA 121
Query: 335 VCSVFLMLINVLVIILKMFWIEAT-LLWRDIAKPYKTRNDGKLYDAYVVYPRNYKSSTDG 393
V + L+L+ +L+ L LLW A NDGKLYDAYV Y
Sbjct: 122 VLASLLVLLALLLAALLYVKCRLNVLLWYQDAYGEVEINDGKLYDAYVSY--------SD 173
Query: 394 ASRVEHFVHQILPDVLENKCGYTLCIYGRDMLPGEDVVTAVETNIRKSRRHIFILTPQIT 453
FV+ IL LE + GY L + RD+LP + + N+ + RR I +L+
Sbjct: 174 CPEDRKFVNFILKPQLERRRGYKLFLDDRDLLPRAEPSADLLVNLSRCRRLIVVLSDAFL 233
Query: 454 HNKEFAYEQEVALHCALIQNDAKVILIEMEALSELDMLQAEALQDSLQHLMKVQGTIKWR 513
++ L C L++ + I I E A L +HL+ + + WR
Sbjct: 234 SRAWCSHSFREGL-CRLLELTRRPIFITFEGQRRDPAHPALRLLRQHRHLVTL---LLWR 289
Query: 514 EDHIANKRSLNSKFWKHVRYQMP 536
+ + +S FWK V+ +P
Sbjct: 290 PGSV----TPSSDFWKEVQLALP 308
>gi|205277449 single Ig IL-1R-related molecule [Homo sapiens]
Length = 410
Score = 70.1 bits (170), Expect = 5e-12
Identities = 75/323 (23%), Positives = 128/323 (39%), Gaps = 29/323 (8%)
Query: 216 APAQNEIKEVEIGKNANLTCSACFGKGTQF-LAAVLWQLNGTKITDFGEPRIQQEEGQNQ 274
+P+++++ +G + L C+A G L +V W +G + G + +
Sbjct: 13 SPSEDQVLRPALGSSVALNCTAWVVSGPHCSLPSVQWLKDGLPLGIGGHYSLHEYSWVKA 72
Query: 275 SFSNGLACLDMVLRIADVKEEDLLLQYDCLALNLHGLRRHTVRLSRKNPIDHHSIYCIIA 334
+ S L + + + + Y ++ + + L R P H + A
Sbjct: 73 NLSEVLVSSVLGVNVTSTEV------YGAFTCSIQNISFSSFTLQRAGPTSH-----VAA 121
Query: 335 VCSVFLMLINVLVIILKMFWIEAT-LLWRDIAKPYKTRNDGKLYDAYVVYPRNYKSSTDG 393
V + L+L+ +L+ L LLW A NDGKLYDAYV Y
Sbjct: 122 VLASLLVLLALLLAALLYVKCRLNVLLWYQDAYGEVEINDGKLYDAYVSY--------SD 173
Query: 394 ASRVEHFVHQILPDVLENKCGYTLCIYGRDMLPGEDVVTAVETNIRKSRRHIFILTPQIT 453
FV+ IL LE + GY L + RD+LP + + N+ + RR I +L+
Sbjct: 174 CPEDRKFVNFILKPQLERRRGYKLFLDDRDLLPRAEPSADLLVNLSRCRRLIVVLSDAFL 233
Query: 454 HNKEFAYEQEVALHCALIQNDAKVILIEMEALSELDMLQAEALQDSLQHLMKVQGTIKWR 513
++ L C L++ + I I E A L +HL+ + + WR
Sbjct: 234 SRAWCSHSFREGL-CRLLELTRRPIFITFEGQRRDPAHPALRLLRQHRHLVTL---LLWR 289
Query: 514 EDHIANKRSLNSKFWKHVRYQMP 536
+ + +S FWK V+ +P
Sbjct: 290 PGSV----TPSSDFWKEVQLALP 308
>gi|205277445 single Ig IL-1R-related molecule [Homo sapiens]
Length = 410
Score = 70.1 bits (170), Expect = 5e-12
Identities = 75/323 (23%), Positives = 128/323 (39%), Gaps = 29/323 (8%)
Query: 216 APAQNEIKEVEIGKNANLTCSACFGKGTQF-LAAVLWQLNGTKITDFGEPRIQQEEGQNQ 274
+P+++++ +G + L C+A G L +V W +G + G + +
Sbjct: 13 SPSEDQVLRPALGSSVALNCTAWVVSGPHCSLPSVQWLKDGLPLGIGGHYSLHEYSWVKA 72
Query: 275 SFSNGLACLDMVLRIADVKEEDLLLQYDCLALNLHGLRRHTVRLSRKNPIDHHSIYCIIA 334
+ S L + + + + Y ++ + + L R P H + A
Sbjct: 73 NLSEVLVSSVLGVNVTSTEV------YGAFTCSIQNISFSSFTLQRAGPTSH-----VAA 121
Query: 335 VCSVFLMLINVLVIILKMFWIEAT-LLWRDIAKPYKTRNDGKLYDAYVVYPRNYKSSTDG 393
V + L+L+ +L+ L LLW A NDGKLYDAYV Y
Sbjct: 122 VLASLLVLLALLLAALLYVKCRLNVLLWYQDAYGEVEINDGKLYDAYVSY--------SD 173
Query: 394 ASRVEHFVHQILPDVLENKCGYTLCIYGRDMLPGEDVVTAVETNIRKSRRHIFILTPQIT 453
FV+ IL LE + GY L + RD+LP + + N+ + RR I +L+
Sbjct: 174 CPEDRKFVNFILKPQLERRRGYKLFLDDRDLLPRAEPSADLLVNLSRCRRLIVVLSDAFL 233
Query: 454 HNKEFAYEQEVALHCALIQNDAKVILIEMEALSELDMLQAEALQDSLQHLMKVQGTIKWR 513
++ L C L++ + I I E A L +HL+ + + WR
Sbjct: 234 SRAWCSHSFREGL-CRLLELTRRPIFITFEGQRRDPAHPALRLLRQHRHLVTL---LLWR 289
Query: 514 EDHIANKRSLNSKFWKHVRYQMP 536
+ + +S FWK V+ +P
Sbjct: 290 PGSV----TPSSDFWKEVQLALP 308
>gi|13186251 fibroblast growth factor receptor 1 isoform 2 precursor
[Homo sapiens]
Length = 820
Score = 63.9 bits (154), Expect = 4e-10
Identities = 88/367 (23%), Positives = 140/367 (38%), Gaps = 70/367 (19%)
Query: 3 FW---ILAILTILMYSTAAKFSKQSWG--LENEALIV--------RCPRQGKPSYTVDWY 49
FW + A L S Q WG +E E+ +V RC R +++W
Sbjct: 9 FWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRC-RLRDDVQSINWL 67
Query: 50 YSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCIVRSPTFNRTGYANVTI----- 104
+ E NR +G+ ++ + ADSG+Y C+ SP+ + T Y +V +
Sbjct: 68 ----RDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALP 123
Query: 105 -------------YKKQSDCNVPDYLMYSTVSGSEKNSKIY-----------CPTIDLYN 140
+K++D P+ + S + K++ CP+ N
Sbjct: 124 SSEDDDDDDDSSSEEKETDNTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPN 183
Query: 141 WTAPLEWFKNCQALQ------GSRYRAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSV 194
T L W KN + + G + R +++D+V+ D G+YTC + NE G S+
Sbjct: 184 PT--LRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTC-IVENEYG---SI 237
Query: 195 TATRSFTVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQLN 254
T V + G PA K V +G N C ++N
Sbjct: 238 NHTYQLDVVERSPHRPILQAGLPAN---KTVALGSNVEFMCKVYSDPQPHIQWLKHIEVN 294
Query: 255 GTKITDFGEPRIQ--QEEGQNQSFSNGLACLDMVLRIADVKEEDLLLQYDCLALNLHGLR 312
G+KI P +Q + G N + VL + +V ED +Y CLA N GL
Sbjct: 295 GSKIGPDNLPYVQILKTAGVNTTDKE-----MEVLHLRNVSFED-AGEYTCLAGNSIGLS 348
Query: 313 RHTVRLS 319
H+ L+
Sbjct: 349 HHSAWLT 355
>gi|13186249 fibroblast growth factor receptor 1 isoform 9 precursor
[Homo sapiens]
Length = 785
Score = 62.8 bits (151), Expect = 8e-10
Identities = 89/369 (24%), Positives = 139/369 (37%), Gaps = 72/369 (19%)
Query: 3 FW---ILAILTILMYSTAAKFSKQSWG--LENEALIV--------RCPRQGKPSYTVDWY 49
FW + A L S Q WG +E E+ +V RC R +++W
Sbjct: 9 FWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRC-RLRDDVQSINWL 67
Query: 50 YSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCIVRSPTFNRTGYANVTIY---- 105
+ E NR +G+ ++ + ADSG+Y C+ SP+ + T Y +V +
Sbjct: 68 ----RDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALP 123
Query: 106 --------------KKQSDCNVPDYLMYSTVSGSE-------------KNSKIYCPTIDL 138
+K++D P+ + + S K K CP+
Sbjct: 124 SSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGT 183
Query: 139 YNWTAPLEWFKNCQALQ------GSRYRAHKSFLVIDNVMTEDAGDYTCKFIHNENGANY 192
N T L W KN + + G + R +++D+V+ D G+YTC + NE G
Sbjct: 184 PNPT--LRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTC-IVENEYG--- 237
Query: 193 SVTATRSFTVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQ 252
S+ T V + G PA K V +G N C +
Sbjct: 238 SINHTYQLDVVERSPHRPILQAGLPAN---KTVALGSNVEFMCKVYSDPQPHIQWLKHIE 294
Query: 253 LNGTKITDFGEPRIQ--QEEGQNQSFSNGLACLDMVLRIADVKEEDLLLQYDCLALNLHG 310
+NG+KI P +Q + G N + VL + +V ED +Y CLA N G
Sbjct: 295 VNGSKIGPDNLPYVQILKTAGVNTTDKE-----MEVLHLRNVSFED-AGEYTCLAGNSIG 348
Query: 311 LRRHTVRLS 319
L H+ L+
Sbjct: 349 LSHHSAWLT 357
>gi|105990522 fibroblast growth factor receptor 1 isoform 1
precursor [Homo sapiens]
Length = 822
Score = 62.8 bits (151), Expect = 8e-10
Identities = 89/369 (24%), Positives = 139/369 (37%), Gaps = 72/369 (19%)
Query: 3 FW---ILAILTILMYSTAAKFSKQSWG--LENEALIV--------RCPRQGKPSYTVDWY 49
FW + A L S Q WG +E E+ +V RC R +++W
Sbjct: 9 FWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRC-RLRDDVQSINWL 67
Query: 50 YSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCIVRSPTFNRTGYANVTIY---- 105
+ E NR +G+ ++ + ADSG+Y C+ SP+ + T Y +V +
Sbjct: 68 ----RDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALP 123
Query: 106 --------------KKQSDCNVPDYLMYSTVSGSE-------------KNSKIYCPTIDL 138
+K++D P+ + + S K K CP+
Sbjct: 124 SSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGT 183
Query: 139 YNWTAPLEWFKNCQALQ------GSRYRAHKSFLVIDNVMTEDAGDYTCKFIHNENGANY 192
N T L W KN + + G + R +++D+V+ D G+YTC + NE G
Sbjct: 184 PNPT--LRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTC-IVENEYG--- 237
Query: 193 SVTATRSFTVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQ 252
S+ T V + G PA K V +G N C +
Sbjct: 238 SINHTYQLDVVERSPHRPILQAGLPAN---KTVALGSNVEFMCKVYSDPQPHIQWLKHIE 294
Query: 253 LNGTKITDFGEPRIQ--QEEGQNQSFSNGLACLDMVLRIADVKEEDLLLQYDCLALNLHG 310
+NG+KI P +Q + G N + VL + +V ED +Y CLA N G
Sbjct: 295 VNGSKIGPDNLPYVQILKTAGVNTTDKE-----MEVLHLRNVSFED-AGEYTCLAGNSIG 348
Query: 311 LRRHTVRLS 319
L H+ L+
Sbjct: 349 LSHHSAWLT 357
>gi|19718734 toll-like receptor 2 [Homo sapiens]
Length = 784
Score = 54.7 bits (130), Expect = 2e-07
Identities = 44/202 (21%), Positives = 94/202 (46%), Gaps = 23/202 (11%)
Query: 336 CSVFLMLINVLVIILK---MFWIEATLLWRDIA-KPYKTRNDGKLYDAYVVYPRNYKSST 391
C++FL+++ V+ + +++++ W KP K + YDA+V Y
Sbjct: 596 CALFLLILLTGVLCHRFHGLWYMKMMWAWLQAKRKPRKAPSRNICYDAFVSY-------- 647
Query: 392 DGASRVEHFVHQILPDVLEN-KCGYTLCIYGRDMLPGEDVVTAVETNIRKSRRHIFILTP 450
+ R ++V ++ LEN + LC++ RD +PG+ ++ + +I KS + +F+L+
Sbjct: 648 --SERDAYWVENLMVQELENFNPPFKLCLHKRDFIPGKWIIDNIIDSIEKSHKTVFVLSE 705
Query: 451 QITHNKEFAYEQEVALHCALIQNDAKVILIEMEALSELDMLQAEALQDSLQHLMKVQGTI 510
++ YE + + +N+ ILI +E + + + Q L+ +M + +
Sbjct: 706 NFVKSEWCKYELDFSHFRLFDENNDAAILILLEPIEKKAIPQRFC---KLRKIMNTKTYL 762
Query: 511 KWREDHIANKRSLNSKFWKHVR 532
+W D + FW ++R
Sbjct: 763 EWPMD-----EAQREGFWVNLR 779
>gi|19924149 toll-like receptor 4 precursor [Homo sapiens]
Length = 839
Score = 54.7 bits (130), Expect = 2e-07
Identities = 66/293 (22%), Positives = 129/293 (44%), Gaps = 36/293 (12%)
Query: 253 LNGTKITDFGEPRIQQEEGQN-QSFSNGLACLDMVLR-IADVKEEDLLLQY--DCLALNL 308
LN ++ D+ I + Q Q F + LA L++ A E LQ+ D L +
Sbjct: 543 LNSLQVLDYSLNHIMTSKKQELQHFPSSLAFLNLTQNDFACTCEHQSFLQWIKDQRQLLV 602
Query: 309 HGLRRHTVRLSRKN--PIDHHSIYC-----IIAVCSVFLMLINVLVIILKMFWIEATLLW 361
R S K P+ +I C II V + +++++V+ +++ F+ LL
Sbjct: 603 EVERMECATPSDKQGMPVLSLNITCQMNKTIIGVSVLSVLVVSVVAVLVYKFYFHLMLL- 661
Query: 362 RDIAKPYKTRNDGKLYDAYVVYPRNYKSSTDGASRVEHFV-HQILPDVLENKCGYTLCIY 420
A K +YDA+V+Y +S+ E +V ++++ ++ E + LC++
Sbjct: 662 ---AGCIKYGRGENIYDAFVIY----------SSQDEDWVRNELVKNLEEGVPPFQLCLH 708
Query: 421 GRDMLPGEDVVT-AVETNIRKSRRHIFILTPQITHNKEFAYEQEVALHCALIQNDAKVIL 479
RD +PG + + KSR+ I +++ ++ +E E+A + + A +I
Sbjct: 709 YRDFIPGVAIAANIIHEGFHKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLSSRAGIIF 768
Query: 480 IEMEALSELDMLQAEALQDSLQHLMKVQGTIKWREDHIANKRSLNSKFWKHVR 532
I ++ + + + Q Q L L+ ++W ED + + FW+ +R
Sbjct: 769 IVLQKVEKTLLRQ----QVELYRLLSRNTYLEW-EDSVLGRHI----FWRRLR 812
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 53.5 bits (127), Expect = 5e-07
Identities = 76/307 (24%), Positives = 113/307 (36%), Gaps = 62/307 (20%)
Query: 29 NEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCI 88
N L + C P T+ WY + + + R +V G+LL+ P V+DSG Y C+
Sbjct: 1463 NSTLTLECESWAVPPPTIRWY--KDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCV 1520
Query: 89 VRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSK----------------IY 132
+ NV I V D+ + E+ ++ +Y
Sbjct: 1521 ATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLY 1580
Query: 133 C-------PTIDLYNWTAPLEWFKNCQALQGSRYRAHKSFLVIDNVMTEDAGDYTCKFIH 185
C P + Y PL LQG R L I V E+AG Y+CK
Sbjct: 1581 CDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGR------VLQIPLVRAENAGRYSCK-AS 1633
Query: 186 NENGANYSVTATRSFTVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCS-ACFGKGTQ 244
NE G ++ T PVI + ++EV + NA+ T S C G
Sbjct: 1634 NEVGEDWLHYELLVLTP---------PVILGDTEELVEEVTV--NASSTVSLQCPALGNP 1682
Query: 245 FLAAVLWQLNGTKITDFGEPRIQ-QEEGQNQSFSNGLACLDMVLRIADVKEEDLLLQYDC 303
+ + W NG + PR+Q E+GQ VL+++ + D Y C
Sbjct: 1683 -VPTISWLQNGLPFSP--SPRLQVLEDGQ-------------VLQVSTAEVAD-AASYMC 1725
Query: 304 LALNLHG 310
+A N G
Sbjct: 1726 VAENQAG 1732
Score = 45.1 bits (105), Expect = 2e-04
Identities = 46/191 (24%), Positives = 78/191 (40%), Gaps = 25/191 (13%)
Query: 27 LENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYT 86
L N + + C G PS T+ W S +VF G++L A +DSG Y+
Sbjct: 799 LVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYS 858
Query: 87 CIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYC---PTIDLYNWTA 143
C+ S + + + D V M ++ G E N + ++ +
Sbjct: 859 CVAVS-----------AVGEDRQDV-VLQVHMPPSILGEELNVSVVANESVALECQSHAM 906
Query: 144 P---LEWFKNCQALQ---GSRYRAHKSFLVIDNVMTEDAGDYTCKFIH----NENGANYS 193
P L W+K+ + L+ G A K+ L +D DAG YTC+ ++ +E N +
Sbjct: 907 PPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGRSEKHYNLN 966
Query: 194 VTATRSFTVKD 204
V F +++
Sbjct: 967 VWVAPVFPLRE 977
Score = 44.3 bits (103), Expect = 3e-04
Identities = 37/169 (21%), Positives = 70/169 (41%), Gaps = 19/169 (11%)
Query: 34 VRCPRQGKPSYTVDWYYSQTNKSIPTQERN--RVFASGQLLKFLPAAVADSGIYTCIVRS 91
+ C +G PS T+ W++ + +P E N R+ G +L+ A SG+Y+C+ S
Sbjct: 425 LECVARGHPSPTLSWHH----EGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASS 480
Query: 92 PTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEK---NSKIYCPTIDLYNWTAPLEWF 148
P A + + + VP L+ + G + P + ++W
Sbjct: 481 P-------AGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWL 533
Query: 149 KN---CQALQGSRYRAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSV 194
+N + L G + + + L ID+V + +G + C+ + A V
Sbjct: 534 QNGRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEV 582
Score = 44.3 bits (103), Expect = 3e-04
Identities = 63/291 (21%), Positives = 112/291 (38%), Gaps = 37/291 (12%)
Query: 27 LENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYT 86
L+ + + C G P + W+ + + + + + + G LL+ L A ++ +G Y+
Sbjct: 1267 LDGQTAHLMCNVTGHPQPKLTWF--KDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYS 1324
Query: 87 CIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNS-KIYC-------PTIDL 138
CI + +T + +++ + + V+ + N + C P I
Sbjct: 1325 CIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITW 1384
Query: 139 YNWTAPLEWFKNCQALQGSRYRAHKSFLVIDNVMTEDAGDYTCKFIHNENG---ANYSVT 195
AP E +N Q L G+ L I N EDAG YTC + NE G NY V
Sbjct: 1385 MKDGAPFEASRNIQLLPGTHG------LQILNAQKEDAGQYTC-VVTNELGEAVKNYHVE 1437
Query: 196 ATRSFTVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQLNG 255
++ + + +KEV+ N+ LT C + W +G
Sbjct: 1438 VLIPPSISKDDPL---------GEVGVKEVKTKVNSTLTLE-CESWAVP-PPTIRWYKDG 1486
Query: 256 TKITD------FGEPRIQQEEGQNQSFSNGLACLDMVLRIADVKEEDLLLQ 300
+T GE R+ Q + S S C+ + D ++ ++L+Q
Sbjct: 1487 QPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQ 1537
Score = 42.7 bits (99), Expect = 9e-04
Identities = 20/63 (31%), Positives = 32/63 (50%), Gaps = 2/63 (3%)
Query: 30 EALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCIV 89
E + + CP +G P V W + +P +R + SG L+ +AD+GI+TC+
Sbjct: 2138 ELVTMVCPVRGSPPIHVSWL--KDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVA 2195
Query: 90 RSP 92
SP
Sbjct: 2196 ASP 2198
Score = 42.0 bits (97), Expect = 0.001
Identities = 64/288 (22%), Positives = 107/288 (37%), Gaps = 39/288 (13%)
Query: 26 GLENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIY 85
GL + ++C G P+ V+W + +P +V GQ+L+ + V D G Y
Sbjct: 229 GLAGADVELQCWTSGVPTPQVEWTKDR-QPVLPGGPHLQVQEDGQVLRITGSHVGDEGRY 287
Query: 86 TCIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCPTIDLYNW---- 141
C+ SP + + ++ T+ GS + ++ L
Sbjct: 288 QCVAFSPAGQQARDFQLRVHAP------------PTIWGSNETGEVAVMEDHLVQLLCEA 335
Query: 142 ----TAPLEWFKNCQALQGSR---YRAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSV 194
T + WFK+ L S Y L + + DAG YTCK A+ +V
Sbjct: 336 RGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCK-------ASNAV 388
Query: 195 TATRSFTVKDEQGFSLFPVI-GAPAQNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQL 253
A T D + P I GA + + + G+ L C A G + L+ W
Sbjct: 389 GAAEKATRLD---VYVPPTIEGAGGRPYVVKAVAGRPVALECVA-RGHPSPTLS---WHH 441
Query: 254 NGTKITDFGEPRIQQEEGQNQSFSNGLACLDMVLRIADVKEEDLLLQY 301
G + + E R++ + + S G A + +A + +LQY
Sbjct: 442 EGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQY 489
Score = 40.4 bits (93), Expect = 0.004
Identities = 37/153 (24%), Positives = 61/153 (39%), Gaps = 12/153 (7%)
Query: 33 IVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCIVRSP 92
++ C P TV WY + + + +R + GQ L+ A V+D G+Y+C V +
Sbjct: 1860 VLSCETDALPEPTVTWY--KDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNV 1917
Query: 93 TFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCPTIDLYNWTAP-LEWFKNC 151
+T+ + N P S V+GS T D+ AP + W K+
Sbjct: 1918 AGEAVRTFTLTVQVPPTFEN-PKTETVSQVAGSP-----LVLTCDVSGVPAPTVTWLKDR 1971
Query: 152 QALQGSRYR---AHKSFLVIDNVMTEDAGDYTC 181
++ S + L + + AG YTC
Sbjct: 1972 MPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTC 2004
Score = 40.4 bits (93), Expect = 0.004
Identities = 39/156 (25%), Positives = 65/156 (41%), Gaps = 14/156 (8%)
Query: 30 EALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCIV 89
E +++ C G P T+ W N + T +V GQL + A+ D+G Y CI
Sbjct: 2772 EEVLLPCEASGIPRPTITWQKEGLN--VATGVSTQVLPGGQL-RIAHASPEDAGNYLCIA 2828
Query: 90 RSPTFNRTGYANVTIYKKQSDCN-VPDYLMYSTVSGSEKNSKIYCPTIDLYNWTAPLEWF 148
++ + G + + N +PD ST GS + P + + W
Sbjct: 2829 KNSAGSAMGKTRLVVQVPPVIENGLPDL---STTEGSHA----FLPCKARGSPEPNITWD 2881
Query: 149 KNCQALQGSRYR---AHKSFLVIDNVMTEDAGDYTC 181
K+ Q + G+ + L++ N+ +DAG YTC
Sbjct: 2882 KDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTC 2917
Score = 36.6 bits (83), Expect = 0.062
Identities = 46/221 (20%), Positives = 83/221 (37%), Gaps = 26/221 (11%)
Query: 22 KQSWGLENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVAD 81
+Q + N ++ + C P+ V WY + ++++ E + L+ A ++D
Sbjct: 1754 EQVTAILNSSVSLPCDVHAHPNPEVTWY--KDSQALSLGEEVFLLPGTHTLQLGRARLSD 1811
Query: 82 SGIYTCIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYC-------P 134
SG+YTC + +++ + P + + + + C P
Sbjct: 1812 SGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEP 1871
Query: 135 TIDLYNWTAPLEWFKNCQALQGSRYRAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSV 194
T+ Y PL + QAL+G + L I D G Y+CK +N +
Sbjct: 1872 TVTWYKDGQPLVLAQRTQALRGGQR------LEIQEAQVSDKGLYSCKV------SNVAG 1919
Query: 195 TATRSFTVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTC 235
A R+FT+ + P P + +V G LTC
Sbjct: 1920 EAVRTFTLT----VQVPPTFENPKTETVSQV-AGSPLVLTC 1955
Score = 34.7 bits (78), Expect = 0.24
Identities = 61/260 (23%), Positives = 92/260 (35%), Gaps = 43/260 (16%)
Query: 27 LENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYT 86
LE + + + C G+P V W + R + G L +D+G YT
Sbjct: 2039 LEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYT 2098
Query: 87 CIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCPTIDLYNWTAP-- 144
C+ +P V + VP + G++ + + +L P
Sbjct: 2099 CVAHNPAGEDARLHTVNVL-------VPPTIK----QGADGSGTLVSRPGELVTMVCPVR 2147
Query: 145 ------LEWFKNCQALQ-GSRYRAHKS--FLVIDNVMTEDAGDYTCKFIHNENGANYSVT 195
+ W K+ L R H S L I V DAG +TC A+ +
Sbjct: 2148 GSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCV------AASPAGV 2201
Query: 196 ATRSFTVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQLNG 255
A R+FT++ + L PV QN++ V G L C A +G L V W +
Sbjct: 2202 ADRNFTLQVQVPPVLEPV---EFQNDVVVVR-GSLVELPCEA---RGVP-LPLVSWMKD- 2252
Query: 256 TKITDFGEPRIQQEEGQNQS 275
GEP + Q Q S
Sbjct: 2253 ------GEPLLSQSLEQGPS 2266
Score = 32.0 bits (71), Expect = 1.5
Identities = 16/62 (25%), Positives = 32/62 (51%), Gaps = 2/62 (3%)
Query: 27 LENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYT 86
LEN ++ + C G P V W+ + ++ + + V G++L+ A ++D+G Y
Sbjct: 707 LENASVTLECLASGVPPPDVSWF--KGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYR 764
Query: 87 CI 88
C+
Sbjct: 765 CV 766
Score = 30.8 bits (68), Expect = 3.4
Identities = 15/57 (26%), Positives = 26/57 (45%), Gaps = 2/57 (3%)
Query: 32 LIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCI 88
L + C G P + W+ + + + E + A G +LK DSG+Y+C+
Sbjct: 1179 LTLLCEAMGIPPPAIRWFRGE--EPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCL 1233
Score = 30.8 bits (68), Expect = 3.4
Identities = 38/162 (23%), Positives = 65/162 (40%), Gaps = 17/162 (10%)
Query: 26 GLENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQE--RNRVFASGQLLKFLPAAVADSG 83
GL L++ C + +P+ + W+ I QE + G+ L+ + ADSG
Sbjct: 2402 GLAPGQLVLECSVEAEPAPKITWH----RDGIVLQEDAHTQFPERGRFLQLQALSTADSG 2457
Query: 84 IYTCIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCPTIDLYNWTA 143
Y+C R+ + + V I+ + + P + S + + + C + A
Sbjct: 2458 DYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSV----NQTALLPCQADGV---PA 2510
Query: 144 PL-EWFKNCQALQGSRYRAH---KSFLVIDNVMTEDAGDYTC 181
PL W K+ L R + L I V+ +DAG Y C
Sbjct: 2511 PLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLC 2552
Score = 29.6 bits (65), Expect = 7.6
Identities = 21/99 (21%), Positives = 41/99 (41%), Gaps = 6/99 (6%)
Query: 9 LTILMYSTAAKFSKQSWGL---ENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRV 65
+ IL+ +A F + + + + +RC G+P+ T++W Q + + R R
Sbjct: 3109 VVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWL--QAGQPLRASRRLRT 3166
Query: 66 FASGQLLKFLPAAVADSGIYTCIVRSPTFNRTGYANVTI 104
G L D+G Y C+ + + T A + +
Sbjct: 3167 LPDGSLW-LENVETGDAGTYDCVAHNLLGSATARAFLVV 3204
Score = 29.3 bits (64), Expect = 9.9
Identities = 24/66 (36%), Positives = 30/66 (45%), Gaps = 6/66 (9%)
Query: 142 TAPLEWFKNCQALQGSRY--RAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSVTATRS 199
T +EW + Q L+ SR L ++NV T DAG Y C HN G S TA
Sbjct: 3146 TPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYDC-VAHNLLG---SATARAF 3201
Query: 200 FTVKDE 205
V+ E
Sbjct: 3202 LVVRGE 3207
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 53.5 bits (127), Expect = 5e-07
Identities = 76/307 (24%), Positives = 113/307 (36%), Gaps = 62/307 (20%)
Query: 29 NEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCI 88
N L + C P T+ WY + + + R +V G+LL+ P V+DSG Y C+
Sbjct: 2654 NSTLTLECESWAVPPPTIRWY--KDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCV 2711
Query: 89 VRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSK----------------IY 132
+ NV I V D+ + E+ ++ +Y
Sbjct: 2712 ATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLY 2771
Query: 133 C-------PTIDLYNWTAPLEWFKNCQALQGSRYRAHKSFLVIDNVMTEDAGDYTCKFIH 185
C P + Y PL LQG R L I V E+AG Y+CK
Sbjct: 2772 CDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGR------VLQIPLVRAENAGRYSCK-AS 2824
Query: 186 NENGANYSVTATRSFTVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCS-ACFGKGTQ 244
NE G ++ T PVI + ++EV + NA+ T S C G
Sbjct: 2825 NEVGEDWLHYELLVLTP---------PVILGDTEELVEEVTV--NASSTVSLQCPALGNP 2873
Query: 245 FLAAVLWQLNGTKITDFGEPRIQ-QEEGQNQSFSNGLACLDMVLRIADVKEEDLLLQYDC 303
+ + W NG + PR+Q E+GQ VL+++ + D Y C
Sbjct: 2874 -VPTISWLQNGLPFSP--SPRLQVLEDGQ-------------VLQVSTAEVAD-AASYMC 2916
Query: 304 LALNLHG 310
+A N G
Sbjct: 2917 VAENQAG 2923
Score = 47.8 bits (112), Expect = 3e-05
Identities = 47/191 (24%), Positives = 78/191 (40%), Gaps = 25/191 (13%)
Query: 27 LENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYT 86
L N + + C G PS T+ W S +VF G++L A +DSG Y+
Sbjct: 1990 LVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYS 2049
Query: 87 CIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYC---PTIDLYNWTA 143
C+ S + + + D V M ++ G E N + ++ +
Sbjct: 2050 CVAVS-----------AVGEDRQDV-VLQVHMPPSILGEELNVSVVANESVALECQSHAM 2097
Query: 144 P---LEWFKNCQALQ---GSRYRAHKSFLVIDNVMTEDAGDYTCKFI----HNENGANYS 193
P L W+K+ + L+ G A K+ L +D DAG YTC+ + H+E N +
Sbjct: 2098 PPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLN 2157
Query: 194 VTATRSFTVKD 204
V F +++
Sbjct: 2158 VWVAPVFPLRE 2168
Score = 44.3 bits (103), Expect = 3e-04
Identities = 37/169 (21%), Positives = 70/169 (41%), Gaps = 19/169 (11%)
Query: 34 VRCPRQGKPSYTVDWYYSQTNKSIPTQERN--RVFASGQLLKFLPAAVADSGIYTCIVRS 91
+ C +G PS T+ W++ + +P E N R+ G +L+ A SG+Y+C+ S
Sbjct: 1616 LECVARGHPSPTLSWHH----EGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASS 1671
Query: 92 PTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEK---NSKIYCPTIDLYNWTAPLEWF 148
P A + + + VP L+ + G + P + ++W
Sbjct: 1672 P-------AGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWL 1724
Query: 149 KN---CQALQGSRYRAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSV 194
+N + L G + + + L ID+V + +G + C+ + A V
Sbjct: 1725 QNGRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEV 1773
Score = 44.3 bits (103), Expect = 3e-04
Identities = 63/291 (21%), Positives = 112/291 (38%), Gaps = 37/291 (12%)
Query: 27 LENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYT 86
L+ + + C G P + W+ + + + + + + G LL+ L A ++ +G Y+
Sbjct: 2458 LDGQTAHLMCNVTGHPQPKLTWF--KDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYS 2515
Query: 87 CIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNS-KIYC-------PTIDL 138
CI + +T + +++ + + V+ + N + C P I
Sbjct: 2516 CIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITW 2575
Query: 139 YNWTAPLEWFKNCQALQGSRYRAHKSFLVIDNVMTEDAGDYTCKFIHNENG---ANYSVT 195
AP E +N Q L G+ L I N EDAG YTC + NE G NY V
Sbjct: 2576 MKDGAPFEASRNIQLLPGTHG------LQILNAQKEDAGQYTC-VVTNELGEAVKNYHVE 2628
Query: 196 ATRSFTVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQLNG 255
++ + + +KEV+ N+ LT C + W +G
Sbjct: 2629 VLIPPSISKDDPL---------GEVGVKEVKTKVNSTLTLE-CESWAVP-PPTIRWYKDG 2677
Query: 256 TKITD------FGEPRIQQEEGQNQSFSNGLACLDMVLRIADVKEEDLLLQ 300
+T GE R+ Q + S S C+ + D ++ ++L+Q
Sbjct: 2678 QPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQ 2728
Score = 42.7 bits (99), Expect = 9e-04
Identities = 20/63 (31%), Positives = 32/63 (50%), Gaps = 2/63 (3%)
Query: 30 EALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCIV 89
E + + CP +G P V W + +P +R + SG L+ +AD+GI+TC+
Sbjct: 3329 ELVTMVCPVRGSPPIHVSWL--KDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVA 3386
Query: 90 RSP 92
SP
Sbjct: 3387 ASP 3389
Score = 42.0 bits (97), Expect = 0.001
Identities = 64/288 (22%), Positives = 107/288 (37%), Gaps = 39/288 (13%)
Query: 26 GLENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIY 85
GL + ++C G P+ V+W + +P +V GQ+L+ + V D G Y
Sbjct: 1420 GLAGADVELQCWTSGVPTPQVEWTKDR-QPVLPGGPHLQVQEDGQVLRITGSHVGDEGRY 1478
Query: 86 TCIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCPTIDLYNW---- 141
C+ SP + + ++ T+ GS + ++ L
Sbjct: 1479 QCVAFSPAGQQARDFQLRVHAP------------PTIWGSNETGEVAVMEDHLVQLLCEA 1526
Query: 142 ----TAPLEWFKNCQALQGSR---YRAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSV 194
T + WFK+ L S Y L + + DAG YTCK A+ +V
Sbjct: 1527 RGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCK-------ASNAV 1579
Query: 195 TATRSFTVKDEQGFSLFPVI-GAPAQNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQL 253
A T D + P I GA + + + G+ L C A G + L+ W
Sbjct: 1580 GAAEKATRLD---VYVPPTIEGAGGRPYVVKAVAGRPVALECVA-RGHPSPTLS---WHH 1632
Query: 254 NGTKITDFGEPRIQQEEGQNQSFSNGLACLDMVLRIADVKEEDLLLQY 301
G + + E R++ + + S G A + +A + +LQY
Sbjct: 1633 EGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQY 1680
Score = 40.4 bits (93), Expect = 0.004
Identities = 37/153 (24%), Positives = 61/153 (39%), Gaps = 12/153 (7%)
Query: 33 IVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCIVRSP 92
++ C P TV WY + + + +R + GQ L+ A V+D G+Y+C V +
Sbjct: 3051 VLSCETDALPEPTVTWY--KDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNV 3108
Query: 93 TFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCPTIDLYNWTAP-LEWFKNC 151
+T+ + N P S V+GS T D+ AP + W K+
Sbjct: 3109 AGEAVRTFTLTVQVPPTFEN-PKTETVSQVAGSP-----LVLTCDVSGVPAPTVTWLKDR 3162
Query: 152 QALQGSRYR---AHKSFLVIDNVMTEDAGDYTC 181
++ S + L + + AG YTC
Sbjct: 3163 MPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTC 3195
Score = 40.4 bits (93), Expect = 0.004
Identities = 39/156 (25%), Positives = 65/156 (41%), Gaps = 14/156 (8%)
Query: 30 EALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCIV 89
E +++ C G P T+ W N + T +V GQL + A+ D+G Y CI
Sbjct: 3963 EEVLLPCEASGIPRPTITWQKEGLN--VATGVSTQVLPGGQL-RIAHASPEDAGNYLCIA 4019
Query: 90 RSPTFNRTGYANVTIYKKQSDCN-VPDYLMYSTVSGSEKNSKIYCPTIDLYNWTAPLEWF 148
++ + G + + N +PD ST GS + P + + W
Sbjct: 4020 KNSAGSAMGKTRLVVQVPPVIENGLPDL---STTEGSHA----FLPCKARGSPEPNITWD 4072
Query: 149 KNCQALQGSRYR---AHKSFLVIDNVMTEDAGDYTC 181
K+ Q + G+ + L++ N+ +DAG YTC
Sbjct: 4073 KDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTC 4108
Score = 36.6 bits (83), Expect = 0.062
Identities = 46/221 (20%), Positives = 83/221 (37%), Gaps = 26/221 (11%)
Query: 22 KQSWGLENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVAD 81
+Q + N ++ + C P+ V WY + ++++ E + L+ A ++D
Sbjct: 2945 EQVTAILNSSVSLPCDVHAHPNPEVTWY--KDSQALSLGEEVFLLPGTHTLQLGRARLSD 3002
Query: 82 SGIYTCIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYC-------P 134
SG+YTC + +++ + P + + + + C P
Sbjct: 3003 SGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEP 3062
Query: 135 TIDLYNWTAPLEWFKNCQALQGSRYRAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSV 194
T+ Y PL + QAL+G + L I D G Y+CK +N +
Sbjct: 3063 TVTWYKDGQPLVLAQRTQALRGGQR------LEIQEAQVSDKGLYSCKV------SNVAG 3110
Query: 195 TATRSFTVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTC 235
A R+FT+ + P P + +V G LTC
Sbjct: 3111 EAVRTFTLT----VQVPPTFENPKTETVSQV-AGSPLVLTC 3146
Score = 35.4 bits (80), Expect = 0.14
Identities = 48/211 (22%), Positives = 82/211 (38%), Gaps = 24/211 (11%)
Query: 30 EALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCIV 89
E ++ C G+ Y + W + +P + L+ D G Y C+
Sbjct: 532 ETAVLSCRVLGEAPYNLTWVRDW--RVLPASTGRVAQLADLSLEISGIIPTDGGRYQCVA 589
Query: 90 RSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCPTIDLYNWTAPLEWFK 149
+ N A+V + +++ P ++++ + ++ T + W +
Sbjct: 590 SNA--NGVTRASVWLLVREA----PQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSR 643
Query: 150 NCQALQGSRYRAH---KSFLVIDNVMTEDAGDYTCKFIHNENGANYSVTATRSFTVKDEQ 206
QALQ R H + L+I V EDAG+Y+C+ NE G + T T +T D
Sbjct: 644 ESQALQEDS-RIHVDAQGTLIIQGVAPEDAGNYSCQ-ATNEVGTDQE-TVTLYYT--DPP 698
Query: 207 GFSLFPVIGAPAQNEIKEVEIGKNANLTCSA 237
S A N + V +G+ A L C A
Sbjct: 699 SVS--------AVNAVVLVAVGEEAVLVCEA 721
Score = 34.7 bits (78), Expect = 0.24
Identities = 61/260 (23%), Positives = 92/260 (35%), Gaps = 43/260 (16%)
Query: 27 LENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYT 86
LE + + + C G+P V W + R + G L +D+G YT
Sbjct: 3230 LEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYT 3289
Query: 87 CIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCPTIDLYNWTAP-- 144
C+ +P V + VP + G++ + + +L P
Sbjct: 3290 CVAHNPAGEDARLHTVNVL-------VPPTIK----QGADGSGTLVSRPGELVTMVCPVR 3338
Query: 145 ------LEWFKNCQALQ-GSRYRAHKS--FLVIDNVMTEDAGDYTCKFIHNENGANYSVT 195
+ W K+ L R H S L I V DAG +TC A+ +
Sbjct: 3339 GSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCV------AASPAGV 3392
Query: 196 ATRSFTVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQLNG 255
A R+FT++ + L PV QN++ V G L C A +G L V W +
Sbjct: 3393 ADRNFTLQVQVPPVLEPV---EFQNDVVVVR-GSLVELPCEA---RGVP-LPLVSWMKD- 3443
Query: 256 TKITDFGEPRIQQEEGQNQS 275
GEP + Q Q S
Sbjct: 3444 ------GEPLLSQSLEQGPS 3457
Score = 32.0 bits (71), Expect = 1.5
Identities = 16/62 (25%), Positives = 32/62 (51%), Gaps = 2/62 (3%)
Query: 27 LENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYT 86
LEN ++ + C G P V W+ + ++ + + V G++L+ A ++D+G Y
Sbjct: 1898 LENASVTLECLASGVPPPDVSWF--KGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYR 1955
Query: 87 CI 88
C+
Sbjct: 1956 CV 1957
Score = 30.8 bits (68), Expect = 3.4
Identities = 51/222 (22%), Positives = 80/222 (36%), Gaps = 41/222 (18%)
Query: 36 CPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCIVRSPTFN 95
CP +G P V W +++ + Q V G L + ADSG Y C + +
Sbjct: 1228 CPARGTPKPQVTWRKGPSSEPLHGQPGVAVLEEGSLF-LASVSPADSGDYECQATNEVGS 1286
Query: 96 RTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNS-KIYCPTIDLYNWTAP-LEWFKNCQ- 152
+ A + +Y S + + + VSG S + C D + P + W K+ Q
Sbjct: 1287 TSRRAKLVVYVPPS---IREDGRKANVSGMAGQSLTLEC---DANGFPVPEIVWLKDAQL 1340
Query: 153 -----------------ALQGSRYRAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSVT 195
+ G R L + D+G Y+C+ N + T
Sbjct: 1341 VGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFPRIQEGDSGLYSCR------AENQAGT 1394
Query: 196 ATRSFTVKDEQGFSLFP--VIGAPAQNEIKEVEIGKNANLTC 235
A R F + L P V+GA A E+ + G + L C
Sbjct: 1395 AQRDFHL-----LVLTPPSVLGAGAAQEVLGL-AGADVELQC 1430
Score = 30.8 bits (68), Expect = 3.4
Identities = 15/57 (26%), Positives = 26/57 (45%), Gaps = 2/57 (3%)
Query: 32 LIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCI 88
L + C G P + W+ + + + E + A G +LK DSG+Y+C+
Sbjct: 2370 LTLLCEAMGIPPPAIRWFRGE--EPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCL 2424
Score = 30.8 bits (68), Expect = 3.4
Identities = 38/162 (23%), Positives = 65/162 (40%), Gaps = 17/162 (10%)
Query: 26 GLENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQE--RNRVFASGQLLKFLPAAVADSG 83
GL L++ C + +P+ + W+ I QE + G+ L+ + ADSG
Sbjct: 3593 GLAPGQLVLECSVEAEPAPKITWH----RDGIVLQEDAHTQFPERGRFLQLQALSTADSG 3648
Query: 84 IYTCIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCPTIDLYNWTA 143
Y+C R+ + + V I+ + + P + S + + + C + A
Sbjct: 3649 DYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSV----NQTALLPCQADGV---PA 3701
Query: 144 PL-EWFKNCQALQGSRYRAH---KSFLVIDNVMTEDAGDYTC 181
PL W K+ L R + L I V+ +DAG Y C
Sbjct: 3702 PLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLC 3743
Score = 29.6 bits (65), Expect = 7.6
Identities = 21/99 (21%), Positives = 41/99 (41%), Gaps = 6/99 (6%)
Query: 9 LTILMYSTAAKFSKQSWGL---ENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRV 65
+ IL+ +A F + + + + +RC G+P+ T++W Q + + R R
Sbjct: 4300 VVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWL--QAGQPLRASRRLRT 4357
Query: 66 FASGQLLKFLPAAVADSGIYTCIVRSPTFNRTGYANVTI 104
G L D+G Y C+ + + T A + +
Sbjct: 4358 LPDGSLW-LENVETGDAGTYDCVAHNLLGSATARAFLVV 4395
Score = 29.3 bits (64), Expect = 9.9
Identities = 24/66 (36%), Positives = 30/66 (45%), Gaps = 6/66 (9%)
Query: 142 TAPLEWFKNCQALQGSRY--RAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSVTATRS 199
T +EW + Q L+ SR L ++NV T DAG Y C HN G S TA
Sbjct: 4337 TPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYDC-VAHNLLG---SATARAF 4392
Query: 200 FTVKDE 205
V+ E
Sbjct: 4393 LVVRGE 4398
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 53.5 bits (127), Expect = 5e-07
Identities = 76/307 (24%), Positives = 113/307 (36%), Gaps = 62/307 (20%)
Query: 29 NEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCI 88
N L + C P T+ WY + + + R +V G+LL+ P V+DSG Y C+
Sbjct: 1372 NSTLTLECESWAVPPPTIRWY--KDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCV 1429
Query: 89 VRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSK----------------IY 132
+ NV I V D+ + E+ ++ +Y
Sbjct: 1430 ATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLY 1489
Query: 133 C-------PTIDLYNWTAPLEWFKNCQALQGSRYRAHKSFLVIDNVMTEDAGDYTCKFIH 185
C P + Y PL LQG R L I V E+AG Y+CK
Sbjct: 1490 CDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGR------VLQIPLVRAENAGRYSCK-AS 1542
Query: 186 NENGANYSVTATRSFTVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCS-ACFGKGTQ 244
NE G ++ T PVI + ++EV + NA+ T S C G
Sbjct: 1543 NEVGEDWLHYELLVLTP---------PVILGDTEELVEEVTV--NASSTVSLQCPALGNP 1591
Query: 245 FLAAVLWQLNGTKITDFGEPRIQ-QEEGQNQSFSNGLACLDMVLRIADVKEEDLLLQYDC 303
+ + W NG + PR+Q E+GQ VL+++ + D Y C
Sbjct: 1592 -VPTISWLQNGLPFSP--SPRLQVLEDGQ-------------VLQVSTAEVAD-AASYMC 1634
Query: 304 LALNLHG 310
+A N G
Sbjct: 1635 VAENQAG 1641
Score = 47.8 bits (112), Expect = 3e-05
Identities = 47/191 (24%), Positives = 78/191 (40%), Gaps = 25/191 (13%)
Query: 27 LENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYT 86
L N + + C G PS T+ W S +VF G++L A +DSG Y+
Sbjct: 708 LVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYS 767
Query: 87 CIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYC---PTIDLYNWTA 143
C+ S + + + D V M ++ G E N + ++ +
Sbjct: 768 CVAVS-----------AVGEDRQDV-VLQVHMPPSILGEELNVSVVANESVALECQSHAM 815
Query: 144 P---LEWFKNCQALQ---GSRYRAHKSFLVIDNVMTEDAGDYTCKFI----HNENGANYS 193
P L W+K+ + L+ G A K+ L +D DAG YTC+ + H+E N +
Sbjct: 816 PPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLN 875
Query: 194 VTATRSFTVKD 204
V F +++
Sbjct: 876 VWVAPVFPLRE 886
Score = 45.8 bits (107), Expect = 1e-04
Identities = 64/291 (21%), Positives = 113/291 (38%), Gaps = 37/291 (12%)
Query: 27 LENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYT 86
L+ + + C G P + W+ + + + + + + G LL+ L A ++ +G Y+
Sbjct: 1176 LDGQTAHLMCNVTGHPQPKLTWF--KDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYS 1233
Query: 87 CIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNS-KIYC-------PTIDL 138
CI + +T + +++ + + V+ + N + C P I
Sbjct: 1234 CIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITW 1293
Query: 139 YNWTAPLEWFKNCQALQGSRYRAHKSFLVIDNVMTEDAGDYTCKFIHNENG---ANYSVT 195
AP E +N Q L G+ L I N EDAG YTC + NE G NY V
Sbjct: 1294 MKDGAPFEASRNIQLLPGTHG------LQILNAQKEDAGQYTC-VVTNELGEAVKNYHVE 1346
Query: 196 ATRSFTVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQLNG 255
++ + A+ +KEV+ N+ LT C + W +G
Sbjct: 1347 VLIPPSISKDDPL---------AEVGVKEVKTKVNSTLTLE-CESWAVP-PPTIRWYKDG 1395
Query: 256 TKITD------FGEPRIQQEEGQNQSFSNGLACLDMVLRIADVKEEDLLLQ 300
+T GE R+ Q + S S C+ + D ++ ++L+Q
Sbjct: 1396 QPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQ 1446
Score = 44.3 bits (103), Expect = 3e-04
Identities = 37/169 (21%), Positives = 70/169 (41%), Gaps = 19/169 (11%)
Query: 34 VRCPRQGKPSYTVDWYYSQTNKSIPTQERN--RVFASGQLLKFLPAAVADSGIYTCIVRS 91
+ C +G PS T+ W++ + +P E N R+ G +L+ A SG+Y+C+ S
Sbjct: 334 LECVARGHPSPTLSWHH----EGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASS 389
Query: 92 PTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEK---NSKIYCPTIDLYNWTAPLEWF 148
P A + + + VP L+ + G + P + ++W
Sbjct: 390 P-------AGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWL 442
Query: 149 KN---CQALQGSRYRAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSV 194
+N + L G + + + L ID+V + +G + C+ + A V
Sbjct: 443 QNGRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEV 491
Score = 42.7 bits (99), Expect = 9e-04
Identities = 20/63 (31%), Positives = 32/63 (50%), Gaps = 2/63 (3%)
Query: 30 EALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCIV 89
E + + CP +G P V W + +P +R + SG L+ +AD+GI+TC+
Sbjct: 2047 ELVTMVCPVRGSPPIHVSWL--KDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVA 2104
Query: 90 RSP 92
SP
Sbjct: 2105 ASP 2107
Score = 42.0 bits (97), Expect = 0.001
Identities = 64/288 (22%), Positives = 107/288 (37%), Gaps = 39/288 (13%)
Query: 26 GLENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIY 85
GL + ++C G P+ V+W + +P +V GQ+L+ + V D G Y
Sbjct: 138 GLAGADVELQCWTSGVPTPQVEWTKDR-QPVLPGGPHLQVQEDGQVLRITGSHVGDEGRY 196
Query: 86 TCIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCPTIDLYNW---- 141
C+ SP + + ++ T+ GS + ++ L
Sbjct: 197 QCVAFSPAGQQARDFQLRVHAP------------PTIWGSNETGEVAVMEDHLVQLLCEA 244
Query: 142 ----TAPLEWFKNCQALQGSR---YRAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSV 194
T + WFK+ L S Y L + + DAG YTCK A+ +V
Sbjct: 245 RGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCK-------ASNAV 297
Query: 195 TATRSFTVKDEQGFSLFPVI-GAPAQNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQL 253
A T D + P I GA + + + G+ L C A G + L+ W
Sbjct: 298 GAAEKATRLD---VYVPPTIEGAGGRPYVVKAVAGRPVALECVA-RGHPSPTLS---WHH 350
Query: 254 NGTKITDFGEPRIQQEEGQNQSFSNGLACLDMVLRIADVKEEDLLLQY 301
G + + E R++ + + S G A + +A + +LQY
Sbjct: 351 EGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQY 398
Score = 40.4 bits (93), Expect = 0.004
Identities = 37/153 (24%), Positives = 61/153 (39%), Gaps = 12/153 (7%)
Query: 33 IVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCIVRSP 92
++ C P TV WY + + + +R + GQ L+ A V+D G+Y+C V +
Sbjct: 1769 VLSCETDALPEPTVTWY--KDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNV 1826
Query: 93 TFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCPTIDLYNWTAP-LEWFKNC 151
+T+ + N P S V+GS T D+ AP + W K+
Sbjct: 1827 AGEAVRTFTLTVQVPPTFEN-PKTETVSQVAGSP-----LVLTCDVSGVPAPTVTWLKDR 1880
Query: 152 QALQGSRYR---AHKSFLVIDNVMTEDAGDYTC 181
++ S + L + + AG YTC
Sbjct: 1881 MPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTC 1913
Score = 40.4 bits (93), Expect = 0.004
Identities = 39/156 (25%), Positives = 65/156 (41%), Gaps = 14/156 (8%)
Query: 30 EALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCIV 89
E +++ C G P T+ W N + T +V GQL + A+ D+G Y CI
Sbjct: 2681 EEVLLPCEASGIPRPTITWQKEGLN--VATGVSTQVLPGGQL-RIAHASPEDAGNYLCIA 2737
Query: 90 RSPTFNRTGYANVTIYKKQSDCN-VPDYLMYSTVSGSEKNSKIYCPTIDLYNWTAPLEWF 148
++ + G + + N +PD ST GS + P + + W
Sbjct: 2738 KNSAGSAMGKTRLVVQVPPVIENGLPDL---STTEGSHA----FLPCKARGSPEPNITWD 2790
Query: 149 KNCQALQGSRYR---AHKSFLVIDNVMTEDAGDYTC 181
K+ Q + G+ + L++ N+ +DAG YTC
Sbjct: 2791 KDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTC 2826
Score = 36.6 bits (83), Expect = 0.062
Identities = 46/221 (20%), Positives = 83/221 (37%), Gaps = 26/221 (11%)
Query: 22 KQSWGLENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVAD 81
+Q + N ++ + C P+ V WY + ++++ E + L+ A ++D
Sbjct: 1663 EQVTAILNSSVSLPCDVHAHPNPEVTWY--KDSQALSLGEEVFLLPGTHTLQLGRARLSD 1720
Query: 82 SGIYTCIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYC-------P 134
SG+YTC + +++ + P + + + + C P
Sbjct: 1721 SGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEP 1780
Query: 135 TIDLYNWTAPLEWFKNCQALQGSRYRAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSV 194
T+ Y PL + QAL+G + L I D G Y+CK +N +
Sbjct: 1781 TVTWYKDGQPLVLAQRTQALRGGQR------LEIQEAQVSDKGLYSCKV------SNVAG 1828
Query: 195 TATRSFTVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTC 235
A R+FT+ + P P + +V G LTC
Sbjct: 1829 EAVRTFTLT----VQVPPTFENPKTETVSQV-AGSPLVLTC 1864
Score = 34.7 bits (78), Expect = 0.24
Identities = 61/260 (23%), Positives = 92/260 (35%), Gaps = 43/260 (16%)
Query: 27 LENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYT 86
LE + + + C G+P V W + R + G L +D+G YT
Sbjct: 1948 LEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYT 2007
Query: 87 CIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCPTIDLYNWTAP-- 144
C+ +P V + VP + G++ + + +L P
Sbjct: 2008 CVAHNPAGEDARLHTVNVL-------VPPTIK----QGADGSGTLVSRPGELVTMVCPVR 2056
Query: 145 ------LEWFKNCQALQ-GSRYRAHKS--FLVIDNVMTEDAGDYTCKFIHNENGANYSVT 195
+ W K+ L R H S L I V DAG +TC A+ +
Sbjct: 2057 GSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCV------AASPAGV 2110
Query: 196 ATRSFTVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQLNG 255
A R+FT++ + L PV QN++ V G L C A +G L V W +
Sbjct: 2111 ADRNFTLQVQVPPVLEPV---EFQNDVVVVR-GSLVELPCEA---RGVP-LPLVSWMKD- 2161
Query: 256 TKITDFGEPRIQQEEGQNQS 275
GEP + Q Q S
Sbjct: 2162 ------GEPLLSQSLEQGPS 2175
Score = 32.0 bits (71), Expect = 1.5
Identities = 16/62 (25%), Positives = 32/62 (51%), Gaps = 2/62 (3%)
Query: 27 LENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYT 86
LEN ++ + C G P V W+ + ++ + + V G++L+ A ++D+G Y
Sbjct: 616 LENASVTLECLASGVPPPDVSWF--KGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYR 673
Query: 87 CI 88
C+
Sbjct: 674 CV 675
Score = 30.8 bits (68), Expect = 3.4
Identities = 15/57 (26%), Positives = 26/57 (45%), Gaps = 2/57 (3%)
Query: 32 LIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCI 88
L + C G P + W+ + + + E + A G +LK DSG+Y+C+
Sbjct: 1088 LTLLCEAMGIPPPAIRWFRGE--EPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCL 1142
Score = 30.8 bits (68), Expect = 3.4
Identities = 38/162 (23%), Positives = 65/162 (40%), Gaps = 17/162 (10%)
Query: 26 GLENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQE--RNRVFASGQLLKFLPAAVADSG 83
GL L++ C + +P+ + W+ I QE + G+ L+ + ADSG
Sbjct: 2311 GLAPGQLVLECSVEAEPAPKITWH----RDGIVLQEDAHTQFPERGRFLQLQALSTADSG 2366
Query: 84 IYTCIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCPTIDLYNWTA 143
Y+C R+ + + V I+ + + P + S + + + C + A
Sbjct: 2367 DYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSV----NQTALLPCQADGV---PA 2419
Query: 144 PL-EWFKNCQALQGSRYRAH---KSFLVIDNVMTEDAGDYTC 181
PL W K+ L R + L I V+ +DAG Y C
Sbjct: 2420 PLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLC 2461
Score = 29.6 bits (65), Expect = 7.6
Identities = 21/99 (21%), Positives = 41/99 (41%), Gaps = 6/99 (6%)
Query: 9 LTILMYSTAAKFSKQSWGL---ENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRV 65
+ IL+ +A F + + + + +RC G+P+ T++W Q + + R R
Sbjct: 3018 VVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWL--QAGQPLRASRRLRT 3075
Query: 66 FASGQLLKFLPAAVADSGIYTCIVRSPTFNRTGYANVTI 104
G L D+G Y C+ + + T A + +
Sbjct: 3076 LPDGSLW-LENVETGDAGTYDCVAHNLLGSATARAFLVV 3113
Score = 29.3 bits (64), Expect = 9.9
Identities = 24/66 (36%), Positives = 30/66 (45%), Gaps = 6/66 (9%)
Query: 142 TAPLEWFKNCQALQGSRY--RAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSVTATRS 199
T +EW + Q L+ SR L ++NV T DAG Y C HN G S TA
Sbjct: 3055 TPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYDC-VAHNLLG---SATARAF 3110
Query: 200 FTVKDE 205
V+ E
Sbjct: 3111 LVVRGE 3116
>gi|41350337 toll-like receptor 1 [Homo sapiens]
Length = 786
Score = 52.0 bits (123), Expect = 1e-06
Identities = 35/131 (26%), Positives = 69/131 (52%), Gaps = 10/131 (7%)
Query: 402 HQILPDVLENKCGYTLCIYGRDMLPGEDVVTAVETNIRKSRRHIFILTPQITHNKEFAYE 461
+++LP++ K G +C++ R+ +PG+ +V + T I KS + IF+L+P ++ YE
Sbjct: 653 NELLPNL--EKEGMQICLHERNFVPGKSIVENIITCIEKSYKSIFVLSPNFVQSEWCHYE 710
Query: 462 QEVALHCALIQNDAKVILIEMEALSELDMLQAEALQDSLQHLMKVQGTIKWREDHIANKR 521
A H + +ILI +E + + + + L+ LM + ++W ++ +KR
Sbjct: 711 LYFAHHNLFHEGSNSLILILLEPIPQYSI---PSSYHKLKSLMARRTYLEWPKE--KSKR 765
Query: 522 SLNSKFWKHVR 532
L FW ++R
Sbjct: 766 GL---FWANLR 773
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 49.7 bits (117), Expect = 7e-06
Identities = 65/283 (22%), Positives = 114/283 (40%), Gaps = 40/283 (14%)
Query: 27 LENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYT 86
L + ++ + C G P ++W + +P R+ A+GQ+++ + A V+D +YT
Sbjct: 3355 LVDTSINIECRATGTPPPQINWL--KNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYT 3412
Query: 87 CIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCPTIDLYNWTAP-L 145
C+ + + N+ ++ + N + + GS ++ + C T AP +
Sbjct: 3413 CVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGS--STSMACIT---DGTPAPSM 3467
Query: 146 EWFKNCQALQGSRY---RAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSVTATRSFTV 202
W ++ Q L + H L + TED+G YTC NE G ++ F +
Sbjct: 3468 AWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTC-IASNEAG-----EVSKHFIL 3521
Query: 203 KDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQLNGTKITDFG 262
K + P I ++E V + LTC A + K+T
Sbjct: 3522 KVLEP----PHINGSEEHEEISVIVNNPLELTCIAS-------------GIPAPKMTWMK 3564
Query: 263 EPRIQQEEGQNQSFSNGLACLDMVLRIADVKEEDLLLQYDCLA 305
+ R + Q Q+ G VLRI+ + ED +Y CLA
Sbjct: 3565 DGRPLPQTDQVQTLGGG-----EVLRISTAQVED-TGRYTCLA 3601
Score = 47.4 bits (111), Expect = 4e-05
Identities = 59/290 (20%), Positives = 111/290 (38%), Gaps = 43/290 (14%)
Query: 27 LENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYT 86
L N++ ++ C G P+ W + + + + ++ ++G++L+ L + D G Y
Sbjct: 2885 LVNKSALIECLSSGSPAPRNSW--QKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYV 2942
Query: 87 CIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCPTIDLYNWTAP-L 145
C+ + + Y N+ ++ S + V + T ++ + P L
Sbjct: 2943 CVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVV------NNFISLTCEVSGFPPPDL 2996
Query: 146 EWFKNCQALQ---GSRYRAHKSFLVIDNVMTEDAGDYTCKFIH--NENGANYSVTATRSF 200
W KN Q ++ + L I D G+YTC I+ E+ +S+T
Sbjct: 2997 SWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPP 3056
Query: 201 TVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQLNGTKITD 260
++KD SL + V G + +L C + + W NG IT+
Sbjct: 3057 SIKDHDSESL----------SVVNVREGTSVSLECES----NAVPPPVITWYKNGRMITE 3102
Query: 261 FGEPRIQQEEGQNQSFSNGLACLDMVLRIADVKEEDLLLQYDCLALNLHG 310
I +GQ + ++ A+V + QY C A+N+ G
Sbjct: 3103 STHVEI-LADGQM-----------LHIKKAEVSDTG---QYVCRAINVAG 3137
Score = 47.0 bits (110), Expect = 5e-05
Identities = 40/162 (24%), Positives = 72/162 (44%), Gaps = 16/162 (9%)
Query: 28 ENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTC 87
E +++ + C G P + W+ + + + E + + + G+ L+ V +G YTC
Sbjct: 2493 EKQSVTLTCEVTGNPVPEITWH--KDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTC 2550
Query: 88 IVRSP------TFNRTGYANVTIYKKQSDCNVPDY-LMYSTVSGSEKNSKIYCP-TIDLY 139
+ SP +F+ + + TI SD N D ++ ++ + + Y P TI +
Sbjct: 2551 LASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWF 2610
Query: 140 NWTAPLEWFKNCQALQGSRYRAHKSFLVIDNVMTEDAGDYTC 181
PLE +N + L G R L I N ++AG Y+C
Sbjct: 2611 KDGTPLESNRNIRILPGGR------TLQILNAQEDNAGRYSC 2646
Score = 45.1 bits (105), Expect = 2e-04
Identities = 70/296 (23%), Positives = 114/296 (38%), Gaps = 48/296 (16%)
Query: 29 NEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCI 88
N L + C PS ++ WY + + + + + + A+G L+ A ++D+G YTC+
Sbjct: 2689 NNTLTLECEAYAIPSASLSWY--KDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCV 2746
Query: 89 VRSPTFNRTGYANVTIYKKQSDCNVPDY-LMYSTVSGSEKNSKIYCPTIDLYNWT--AP- 144
+ +V I S + + M T E I I LY T AP
Sbjct: 2747 ASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPP 2806
Query: 145 --LEWFKNCQALQGS---RYRAHKSFLVIDNVMTEDAGDYTCKFIH--NENGANYSVTAT 197
L W+K+ L S L I EDAG YTC ++ E+ Y V
Sbjct: 2807 PTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRV- 2865
Query: 198 RSFTVKDEQGFSLFPVIGAPAQNEIKE---VEIGKNANLTCSACFGKGTQFLAAVLWQLN 254
L P I A +++ E V + K+A + C + + WQ +
Sbjct: 2866 ------------LVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPR----NSWQKD 2909
Query: 255 GTKITDFGEPRIQQEEGQNQSFSNGLACLDMVLRIADVKEEDLLLQYDCLALNLHG 310
G + E+ ++ SNG +L+I + + D + +Y C+A N G
Sbjct: 2910 GQPLL---------EDDHHKFLSNG-----RILQILNTQITD-IGRYVCVAENTAG 2950
Score = 44.3 bits (103), Expect = 3e-04
Identities = 40/165 (24%), Positives = 67/165 (40%), Gaps = 23/165 (13%)
Query: 27 LENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYT 86
+E ++ + C G P ++ W+ S+ R + + G++L+ + + D+G YT
Sbjct: 2399 VEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVR--ILSGGRMLRLMQTTMEDAGQYT 2456
Query: 87 CIVRSPTFNRTGYANVTIYKKQSDCNVPDYLM----YSTVSGSEKNS-KIYCPTIDLYNW 141
C+VR+ +++ VP +++ V EK S + C N
Sbjct: 2457 CVVRNAAGEERKIFGLSVL-------VPPHIVGENTLEDVKVKEKQSVTLTCEVTG--NP 2507
Query: 142 TAPLEWFKNCQALQGSRYRAHK-----SFLVIDNVMTEDAGDYTC 181
+ W K+ Q LQ AH FL I NV G YTC
Sbjct: 2508 VPEITWHKDGQPLQED--EAHHIISGGRFLQITNVQVPHTGRYTC 2550
Score = 43.9 bits (102), Expect = 4e-04
Identities = 62/300 (20%), Positives = 118/300 (39%), Gaps = 51/300 (17%)
Query: 29 NEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCI 88
N + + C +G P+ ++ W + S +V + G++L A ++D+G YTC+
Sbjct: 2026 NNPVRLECEARGIPAPSLTWLKDGSPVS-SFSNGLQVLSGGRILALTSAQISDTGRYTCV 2084
Query: 89 VRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCPTIDLYNWT-----A 143
N G +KQ D ++ Y+ + + + S + ++L +
Sbjct: 2085 ----AVNAAG-------EKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPP 2133
Query: 144 PLEWFKNCQAL---QGSRYRAHKSFLVIDNVMTEDAGDYTCKF--IHNENGANYSVTATR 198
L W K+ L G ++S L I++ +D G YTC+ + + NY+V
Sbjct: 2134 TLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNV---- 2189
Query: 199 SFTVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQLNGTKI 258
+ P IG +E+ ++ + NL C G ++W+ G+ +
Sbjct: 2190 --------NIWVPPNIG--GSDELTQLTV-IEGNLISLLCESSGIP-PPNLIWKKKGSPV 2237
Query: 259 TDFGEPRIQQEEGQNQSFSNGLACLDMVLRIADVKEEDLLLQYDCLALNLHGLRRHTVRL 318
R++ G Q L+I+ ++ D L Y C+A N+ G + L
Sbjct: 2238 LTDSMGRVRILSGGRQ------------LQISIAEKSDAAL-YSCVASNVAGTAKKEYNL 2284
Score = 43.1 bits (100), Expect = 7e-04
Identities = 69/305 (22%), Positives = 120/305 (39%), Gaps = 58/305 (19%)
Query: 29 NEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERN-RVFASGQLLKFLPAAVADSGIYTC 87
N+ + CP +G P T+ W ++ + + +E + G LL D+G Y C
Sbjct: 1281 NQRIEFPCPAKGTPKPTIKWLHN--GRELTGREPGISILEDGTLLVIASVTPYDNGEYIC 1338
Query: 88 IVRSPT------FNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCPTIDLYNW 141
+ + +N + I K+ NV L T ++C ++
Sbjct: 1339 VAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLT--------NLFC---EVEGT 1387
Query: 142 TAP-LEWFK-NCQALQGSRYRA--HKSFLVIDNVMTEDAGDYTCKFIHNENGANYSVTAT 197
+P + W+K N Q + S + + L + EDAG Y+CK I N + T+
Sbjct: 1388 PSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAI------NIAGTSQ 1441
Query: 198 RSFTVKDEQGFSLFP--VIGAPAQNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQLNG 255
+ F + L P +IG NE+ V + ++ L C KGT F + W +G
Sbjct: 1442 KYFNID-----VLVPPTIIGTNFPNEV-SVVLNRDVALECQV---KGTPF-PDIHWFKDG 1491
Query: 256 TKITDFGEPRIQ-QEEGQNQSFSNGLACLDMVLRIADVKEEDLLLQYDCLALNLHGLRRH 314
K G+P ++ + GQ VL + + + D +Y C N G +
Sbjct: 1492 -KPLFLGDPNVELLDRGQ-------------VLHLKNARRND-KGRYQCTVSNAAGKQAK 1536
Query: 315 TVRLS 319
++L+
Sbjct: 1537 DIKLT 1541
Score = 42.4 bits (98), Expect = 0.001
Identities = 54/216 (25%), Positives = 92/216 (42%), Gaps = 32/216 (14%)
Query: 29 NEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCI 88
++ + + C G P + W+ + ++I R RV +SG L + D+G YTC+
Sbjct: 4093 DKPITLSCEADGLPPPDITWH--KDGRAIVESIRQRVLSSGSL-QIAFVQPGDAGHYTCM 4149
Query: 89 VRSPTFNRTGYANVTIYKKQSDCNVPDYLM----YSTVSGSEKNSKIYCPTIDLYNWTAP 144
+ + + +T++ VP + + TV+ +NS+ P + T
Sbjct: 4150 AANVAGSSSTSTKLTVH-------VPPRIRSTEGHYTVN---ENSQAILPCVADGIPTPA 4199
Query: 145 LEWFKNCQALQG--SRYRAHK-SFLVIDNVMTEDAGDYTCKFIHNENGANYSVTATRSFT 201
+ W K+ L +Y A L+++NV+ ED+G YTC N A T T S T
Sbjct: 4200 INWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCV----ANNAAGEDTHTVSLT 4255
Query: 202 VKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCSA 237
V F+ P G + N+ G+ L+C A
Sbjct: 4256 VHVLPTFTELP--GDVSLNK------GEQLRLSCKA 4283
Score = 42.0 bits (97), Expect = 0.001
Identities = 59/291 (20%), Positives = 116/291 (39%), Gaps = 44/291 (15%)
Query: 34 VRCPRQGKPSYTVDWYYSQTNKSIPTQERN-RVFASGQLLKFLPAAVADSGIYTCIVRSP 92
++C G P+ ++ W + ++ + T + N ++ +SG++L+ + D+G YTC+ +
Sbjct: 1846 LQCIANGIPNPSITWL--KDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNA 1903
Query: 93 TFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCPTIDLYNWTAPLEWFKNCQ 152
+ + +++ S ++ TV S ++ C N + W+K+ +
Sbjct: 1904 AGETQQHIQLHVHEPPS-LEDAGKMLNETVLVSNP-VQLECKAAG--NPVPVITWYKDNR 1959
Query: 153 ALQGS---RYRAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSVTATRSFTVKDEQGFS 209
L GS + + I++ DAG Y C I+ S AT F
Sbjct: 1960 LLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAIN-------SAGATELF-----YSLQ 2007
Query: 210 LFPVIGAPAQNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQLNGTKITDFGEPRIQQE 269
+ N + V + L C A +G ++ W +G+ ++
Sbjct: 2008 VHVAPSISGSNNMVAVVVNNPVRLECEA---RGIP-APSLTWLKDGSPVS---------- 2053
Query: 270 EGQNQSFSNGLACLD--MVLRIADVKEEDLLLQYDCLALNLHGLRRHTVRL 318
SFSNGL L +L + + D +Y C+A+N G ++ + L
Sbjct: 2054 -----SFSNGLQVLSGGRILALTSAQISD-TGRYTCVAVNAAGEKQRDIDL 2098
Score = 41.6 bits (96), Expect = 0.002
Identities = 65/285 (22%), Positives = 108/285 (37%), Gaps = 44/285 (15%)
Query: 34 VRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCIVRSPT 93
+ C QG P + W S+ ++ + V L A +D+GIYTC+ +
Sbjct: 1190 IPCNAQGTPLPVITW--SKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCV--ATN 1245
Query: 94 FNRTGYANVTIYKKQ----SDCNVPDYLMYSTVSGSEKNSKIYCPTIDLYNWTAPLEWFK 149
T +T++ ++ D P +T N +I P ++W
Sbjct: 1246 IAGTDETEITLHVQEPPTVEDLEPP---YNTTFQERVANQRIEFPCPAKGTPKPTIKWLH 1302
Query: 150 NCQALQGSR----YRAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSVTATRSFTVKDE 205
N + L G + LVI +V D G+Y C + NE G T R + +K
Sbjct: 1303 NGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAV-NEAG-----TTERKYNLK-- 1354
Query: 206 QGFSLFPVIGAPAQNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQLNGTKITDFGEPR 265
+ PVI Q V + + NL C +GT ++W + ++T
Sbjct: 1355 --VHVPPVIKDKEQVTNVSVLLNQLTNLFCEV---EGTP-SPIIMWYKDNVQVT------ 1402
Query: 266 IQQEEGQNQSFSNGLACLDMVLRIADVKEEDLLLQYDCLALNLHG 310
E Q+ +NG +L++ ED +Y C A+N+ G
Sbjct: 1403 ---ESSTIQTVNNG-----KILKLFRATPED-AGRYSCKAINIAG 1438
Score = 41.2 bits (95), Expect = 0.003
Identities = 34/159 (21%), Positives = 69/159 (43%), Gaps = 15/159 (9%)
Query: 29 NEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCI 88
N L + C G P+ + W + + +P ++ + G++L+ A V D+G YTC+
Sbjct: 3543 NNPLELTCIASGIPAPKMTWM--KDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCL 3600
Query: 89 VRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCPTIDLYNWTAP---L 145
SP + V ++ + + + + +N ++ T++ + P +
Sbjct: 3601 ASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVL----RNRQV---TLECKSDAVPPPVI 3653
Query: 146 EWFKNCQALQGS---RYRAHKSFLVIDNVMTEDAGDYTC 181
W +N + LQ + R + +L I+N D +YTC
Sbjct: 3654 TWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTC 3692
Score = 39.7 bits (91), Expect = 0.007
Identities = 23/78 (29%), Positives = 34/78 (43%), Gaps = 2/78 (2%)
Query: 28 ENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTC 87
EN L+ C G P+ + W + ER RV A+G L A +D+G YTC
Sbjct: 3262 ENVELV--CNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTC 3319
Query: 88 IVRSPTFNRTGYANVTIY 105
+ +P N+ +Y
Sbjct: 3320 VATNPAGEEDRIFNLNVY 3337
Score = 38.9 bits (89), Expect = 0.013
Identities = 36/151 (23%), Positives = 58/151 (38%), Gaps = 9/151 (5%)
Query: 36 CPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCIVRSPTFN 95
C G P T+ W + R+ + G L+ + +DSG YTCI +
Sbjct: 3173 CDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGK 3232
Query: 96 RTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCPTIDLYNWTAPLEWFKNCQALQ 155
Y ++I S S + G +N ++ C + T ++W K+ + +
Sbjct: 3233 AQKYYFLSIQVPPSVAGAEIPSDVSVLLG--ENVELVCNANGIP--TPLIQWLKDGKPIA 3288
Query: 156 GS-----RYRAHKSFLVIDNVMTEDAGDYTC 181
R A+ S L I +T D G YTC
Sbjct: 3289 SGETERIRVSANGSTLNIYGALTSDTGKYTC 3319
Score = 38.5 bits (88), Expect = 0.016
Identities = 45/175 (25%), Positives = 69/175 (39%), Gaps = 19/175 (10%)
Query: 29 NEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCI 88
N +++ C G PS + W N + T RN L+ A D+G Y C+
Sbjct: 4002 NNPILLPCEATGTPSPFITWQKEGIN--VNTSGRNHAVLPSGGLQISRAVREDAGTYMCV 4059
Query: 89 VRSPTFNRTGYANVTIYKKQSDCNVPDYL---MYSTVSGSEKNSKIYCPTIDLYNWTAPL 145
++P A + K + + VP + + V +K + C L +
Sbjct: 4060 AQNP-------AGTALGKIKLNVQVPPVISPHLKEYVIAVDKPITLSCEADGLP--PPDI 4110
Query: 146 EWFKNCQAL-QGSRYRAHKS-FLVIDNVMTEDAGDYTCKFIHNENGANYSVTATR 198
W K+ +A+ + R R S L I V DAG YTC N A S T+T+
Sbjct: 4111 TWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCM---AANVAGSSSTSTK 4162
Score = 37.4 bits (85), Expect = 0.036
Identities = 38/161 (23%), Positives = 69/161 (42%), Gaps = 19/161 (11%)
Query: 29 NEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCI 88
N L + C G P T+ W + + I ++ ++ +G+ L A V+++G+Y C+
Sbjct: 1749 NNLLELDCHVTGSPPPTIMWL--KDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCM 1806
Query: 89 VRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSG----SEKNSKIYCPTIDLYNWTAP 144
+ + VT++ VP + S +S K + C + N
Sbjct: 1807 AANTAGDHKKEFEVTVH-------VPPTIKSSGLSERVVVKYKPVALQCIANGIPN--PS 1857
Query: 145 LEWFKNCQAL---QGS-RYRAHKSFLVIDNVMTEDAGDYTC 181
+ W K+ Q + QG+ + ++ L I + EDAG YTC
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTC 1898
Score = 36.2 bits (82), Expect = 0.081
Identities = 55/219 (25%), Positives = 85/219 (38%), Gaps = 31/219 (14%)
Query: 29 NEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERN-RVFASGQLLKFLPAAVADSGIYTC 87
N + + C +G P + W+ + K + + N + GQ+L A D G Y C
Sbjct: 1468 NRDVALECQVKGTPFPDIHWF--KDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQC 1525
Query: 88 IVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEK---NS--KIYCPTIDLYNWT 142
V + + +TIY +P + V+ NS K+ C T L
Sbjct: 1526 TVSNAAGKQAKDIKLTIY-------IPPSIKGGNVTTDISVLINSLIKLECETRGLP--M 1576
Query: 143 APLEWFKNCQALQGSR---YRAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSVTATRS 199
+ W+K+ Q + S Y +L I D+ YTC + AN + TA +S
Sbjct: 1577 PAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTC------HVANVAGTAEKS 1630
Query: 200 FTVKDEQGFSLFPVI-GAPAQNEIKEVEIGKNANLTCSA 237
F V + P+I G A K+V I + L C A
Sbjct: 1631 FHV----DVYVPPMIEGNLATPLNKQVVIAHSLTLECKA 1665
Score = 35.4 bits (80), Expect = 0.14
Identities = 70/306 (22%), Positives = 108/306 (35%), Gaps = 58/306 (18%)
Query: 28 ENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLP----------A 77
EN I+ C G P+ ++W +++ V + L K+
Sbjct: 4182 ENSQAILPCVADGIPTPAINW------------KKDNVLLANLLGKYTAEPYGELILENV 4229
Query: 78 AVADSGIYTCIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCPTID 137
+ DSG YTC+ + T ++T++ + +P + + + K +
Sbjct: 4230 VLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLP 4289
Query: 138 LYNWTAPLEWFKNCQALQGSRYRAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSVTAT 197
WT + N H S LVI+ V ED+G Y C EN + V A
Sbjct: 4290 KLTWT----FNNNIIPAHFDSVNGH-SELVIERVSKEDSGTYVCT---AENSVGF-VKAI 4340
Query: 198 RSFTVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQLNGTK 257
VK+ F G N I+ +G NA L C KG + W G
Sbjct: 4341 GFVYVKEPPVFK-----GDYPSNWIE--PLGGNAILNCEV---KGDP-TPTIQWNRKGVD 4389
Query: 258 ITDFGEPRIQQEEGQNQSFSNGLACLDMVLRIADVKEEDLLLQYDCLALNLHGLRRHTVR 317
I RI+Q NG L I ED Y C+A N G+ ++
Sbjct: 4390 IEI--SHRIRQ-------LGNG------SLAIYGTVNED-AGDYTCVATNEAGVVERSMS 4433
Query: 318 LSRKNP 323
L+ ++P
Sbjct: 4434 LTLQSP 4439
Score = 34.7 bits (78), Expect = 0.24
Identities = 38/165 (23%), Positives = 63/165 (38%), Gaps = 28/165 (16%)
Query: 30 EALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCIV 89
+++ + C QG P TV W + + + + G +L+ V+D+G Y C+
Sbjct: 2308 KSISLECEVQGIPPPTVTWM--KDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVA 2365
Query: 90 RSPTFNRTGYANVTIYKKQSDCNVPDYLMYS-----TVSGSEKN--------SKIYCPTI 136
A +T K + P ++ + +S EKN S I P+I
Sbjct: 2366 -------VNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSI 2418
Query: 137 DLYNWTAPLEWFKNCQALQGSRYRAHKSFLVIDNVMTEDAGDYTC 181
+ P+ + + L G R L + EDAG YTC
Sbjct: 2419 TWFKDGWPVSLSNSVRILSGGR------MLRLMQTTMEDAGQYTC 2457
Score = 32.7 bits (73), Expect = 0.90
Identities = 21/79 (26%), Positives = 33/79 (41%), Gaps = 2/79 (2%)
Query: 27 LENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYT 86
L N + + C +G P + WY + + I + + GQ L A V+DS YT
Sbjct: 1560 LINSLIKLECETRGLPMPAITWY--KDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYT 1617
Query: 87 CIVRSPTFNRTGYANVTIY 105
C V + +V +Y
Sbjct: 1618 CHVANVAGTAEKSFHVDVY 1636
Score = 31.2 bits (69), Expect = 2.6
Identities = 31/156 (19%), Positives = 55/156 (35%), Gaps = 7/156 (4%)
Query: 27 LENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYT 86
L E + + C + P + W +T P R+ SG + K +DSG+Y
Sbjct: 1092 LAGEEVTLPCEVKSLPPPIITWA-KETQLISPFSPRHTFLPSGSM-KITETRTSDSGMYL 1149
Query: 87 CIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCPTIDLYNWTAPLE 146
C+ + N T + ++ P +L + + + W+
Sbjct: 1150 CVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKG-- 1207
Query: 147 WFKNCQALQGSRYRAH-KSFLVIDNVMTEDAGDYTC 181
+ + G + ++ L ID DAG YTC
Sbjct: 1208 --GSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTC 1241
Score = 31.2 bits (69), Expect = 2.6
Identities = 65/287 (22%), Positives = 106/287 (36%), Gaps = 47/287 (16%)
Query: 28 ENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTC 87
+ E L + C G P + W + N +I + V +L+ + DSG Y C
Sbjct: 4273 KGEQLRLSCKATGIPLPKLTWTF---NNNIIPAHFDSVNGHSELV-IERVSKEDSGTYVC 4328
Query: 88 IVRSPTFNRTGYANVT--IYKKQSDCNVPDYLMYSTVSGSEKNSKIYCPTIDLYNWTAPL 145
N G+ +Y K+ DY + + N+ + C + T +
Sbjct: 4329 TAE----NSVGFVKAIGFVYVKEPPVFKGDYPS-NWIEPLGGNAILNCEVKG--DPTPTI 4381
Query: 146 EWFKNCQALQGSRY--RAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSVTATRSFTVK 203
+W + ++ S + L I + EDAGDYTC NE G V + S T++
Sbjct: 4382 QWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTC-VATNEAGV---VERSMSLTLQ 4437
Query: 204 DEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQLNGTKITDFGE 263
+L PV + G L C A + + W G I+
Sbjct: 4438 SPPIITLEPVETV--------INAGGKIILNCQAT----GEPQPTITWSRQGHSIS---- 4481
Query: 264 PRIQQEEGQNQSFSNGLACLDMVLRIADVKEEDLLLQYDCLALNLHG 310
++ N +N L IAD ++ED +++C+A NL G
Sbjct: 4482 ----WDDRVNVLSNNS-------LYIADAQKED-TSEFECVARNLMG 4516
Score = 30.8 bits (68), Expect = 3.4
Identities = 16/61 (26%), Positives = 27/61 (44%), Gaps = 2/61 (3%)
Query: 31 ALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCIVR 90
+L + C G PS + W + + + R+ A G+ L+ + A D G Y C+
Sbjct: 1658 SLTLECKAAGNPSPILTWL--KDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVAT 1715
Query: 91 S 91
S
Sbjct: 1716 S 1716
>gi|13186236 fibroblast growth factor receptor 1 isoform 4 precursor
[Homo sapiens]
Length = 731
Score = 48.1 bits (113), Expect = 2e-05
Identities = 55/201 (27%), Positives = 80/201 (39%), Gaps = 23/201 (11%)
Query: 127 KNSKIYCPTIDLYNWTAPLEWFKNCQALQ------GSRYRAHKSFLVIDNVMTEDAGDYT 180
K K CP+ N T L W KN + + G + R +++D+V+ D G+YT
Sbjct: 81 KTVKFKCPSSGTPNPT--LRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYT 138
Query: 181 CKFIHNENGANYSVTATRSFTVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCSACFG 240
C + NE G S+ T V + G PA K V +G N C
Sbjct: 139 C-IVENEYG---SINHTYQLDVVERSPHRPILQAGLPAN---KTVALGSNVEFMCKVYSD 191
Query: 241 KGTQFLAAVLWQLNGTKITDFGEPRIQ--QEEGQNQSFSNGLACLDMVLRIADVKEEDLL 298
++NG+KI P +Q + G N + VL + +V ED
Sbjct: 192 PQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKE-----MEVLHLRNVSFED-A 245
Query: 299 LQYDCLALNLHGLRRHTVRLS 319
+Y CLA N GL H+ L+
Sbjct: 246 GEYTCLAGNSIGLSHHSAWLT 266
>gi|13186234 fibroblast growth factor receptor 1 isoform 3 precursor
[Homo sapiens]
Length = 733
Score = 48.1 bits (113), Expect = 2e-05
Identities = 55/201 (27%), Positives = 80/201 (39%), Gaps = 23/201 (11%)
Query: 127 KNSKIYCPTIDLYNWTAPLEWFKNCQALQ------GSRYRAHKSFLVIDNVMTEDAGDYT 180
K K CP+ N T L W KN + + G + R +++D+V+ D G+YT
Sbjct: 83 KTVKFKCPSSGTPNPT--LRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYT 140
Query: 181 CKFIHNENGANYSVTATRSFTVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCSACFG 240
C + NE G S+ T V + G PA K V +G N C
Sbjct: 141 C-IVENEYG---SINHTYQLDVVERSPHRPILQAGLPAN---KTVALGSNVEFMCKVYSD 193
Query: 241 KGTQFLAAVLWQLNGTKITDFGEPRIQ--QEEGQNQSFSNGLACLDMVLRIADVKEEDLL 298
++NG+KI P +Q + G N + VL + +V ED
Sbjct: 194 PQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKE-----MEVLHLRNVSFED-A 247
Query: 299 LQYDCLALNLHGLRRHTVRLS 319
+Y CLA N GL H+ L+
Sbjct: 248 GEYTCLAGNSIGLSHHSAWLT 268
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 47.4 bits (111), Expect = 4e-05
Identities = 52/206 (25%), Positives = 82/206 (39%), Gaps = 15/206 (7%)
Query: 36 CPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPA-AVADSGIYTCIVRSPTF 94
C G PS T+ W + S+P Q R+ LL +PA AD+G Y C+ SP
Sbjct: 1977 CRAAGVPSATITW--RKEGGSLPPQARSERTDIATLL--IPAITTADAGFYLCVATSPAG 2032
Query: 95 NRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCPTIDLYNWTAPLEWFKNCQAL 154
V + SD + P + S+ + + + + A + W++ +L
Sbjct: 2033 TAQARIQVVVL-SASDASPPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSL 2091
Query: 155 QGSRYRAHKSFLVIDNVMTEDAGDYTCKFIHNENGAN-YSVTATRSFTVKDEQGFSLFPV 213
+ H S L + V D+G+Y C+ ENG+ + T S G S PV
Sbjct: 2092 P-PHTQVHGSRLRLPQVSPADSGEYVCRV---ENGSGPKEASITVSVLHGTHSGPSYTPV 2147
Query: 214 IGAPAQNEIK----EVEIGKNANLTC 235
G+ I+ V G+ +L C
Sbjct: 2148 PGSTRPIRIEPSSSHVAEGQTLDLNC 2173
Score = 45.4 bits (106), Expect = 1e-04
Identities = 50/211 (23%), Positives = 83/211 (39%), Gaps = 16/211 (7%)
Query: 28 ENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTC 87
E + L + C G+ V W+ + S+P + + G LL+ ADSG Y C
Sbjct: 2165 EGQTLDLNCVVPGQAHAQVTWH--KRGGSLPARHQTH----GSLLRLHQVTPADSGEYVC 2218
Query: 88 IVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCPTIDLYNWTAPLEW 147
V + VTI +P + S+ S + + + A + W
Sbjct: 2219 HVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVTW 2278
Query: 148 FKNCQALQGSRYRAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSVTATRSFTVKDEQG 207
+K +L +R++ S L I DAG Y C+ NG S+T T + T
Sbjct: 2279 YKRGGSLP-ARHQVRGSRLYIFQASPADAGQYVCR---ASNGMEASITVTVTGTQGANLA 2334
Query: 208 F---SLFPVIGAPAQNEIKEVEIGKNANLTC 235
+ S P+ P+ +++ E G+ +L C
Sbjct: 2335 YPAGSTQPIRIEPSSSQVAE---GQTLDLNC 2362
Score = 45.4 bits (106), Expect = 1e-04
Identities = 59/240 (24%), Positives = 90/240 (37%), Gaps = 20/240 (8%)
Query: 21 SKQSWGLENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVA 80
S S E + L + C G+ V W+ + S+P + + G L+ L A
Sbjct: 2443 SSSSQVAEGQTLDLNCLVAGQAHAQVTWH--KRGGSLPARHQ----VHGSRLRLLQVTPA 2496
Query: 81 DSGIYTCIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCPTIDLYN 140
DSG Y C V + + VTI ++ S + + Y S S T+DL
Sbjct: 2497 DSGEYVCRVVGSSGTQEASVLVTIQQRLSGSH-SQGVAYPVRIESSSASLANGHTLDLNC 2555
Query: 141 WTA-----PLEWFKNCQALQGSRYRAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSVT 195
A + W+K +L SR++ S L I V D+G+Y C H NGA T
Sbjct: 2556 LVASQAPHTITWYKRGGSLP-SRHQIVGSRLRIPQVTPADSGEYVC---HVSNGAGSRET 2611
Query: 196 ATRSFTVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQLNG 255
+ G S P + P + E + + L + + Q A + W G
Sbjct: 2612 SL--IVTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVARQPQ--AIITWYKRG 2667
Score = 44.7 bits (104), Expect = 2e-04
Identities = 59/225 (26%), Positives = 88/225 (39%), Gaps = 39/225 (17%)
Query: 34 VRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCIVRSPT 93
+RC G P+ T+ W S+ +P Q R G L A DSG Y C SP
Sbjct: 3231 LRCSATGSPAPTIHW--SKLRSPLPWQHR----LEGDTLIIPRVAQQDSGQYICNATSP- 3283
Query: 94 FNRTGYANVTIYKKQSD----CNVPDYLMYSTVSGSEKNSKIYCPTIDLYNWTAPL--EW 147
G+A TI VP+ +++V E ++ C L + T PL +W
Sbjct: 3284 ---AGHAEATIILHVESPPYATTVPE---HASVQAGE-TVQLQC----LAHGTPPLTFQW 3332
Query: 148 FKNCQALQGSRYRAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSVTATRSFTVKDEQG 207
+ +L G R A L + ED+G Y C+ + N+ G S A V+ G
Sbjct: 3333 SRVGSSLPG-RATARNELLHFERAAPEDSGRYRCR-VTNKVG---SAEAFAQLLVQGPPG 3387
Query: 208 FSLFPVIGAPAQN--------EIKEVEIGKNANLTCSACFGKGTQ 244
P PA + +++ IG + C+ +GTQ
Sbjct: 3388 --SLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQ 3430
Score = 44.3 bits (103), Expect = 3e-04
Identities = 47/176 (26%), Positives = 74/176 (42%), Gaps = 16/176 (9%)
Query: 28 ENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTC 87
E + L + C G+ V W+ + S+P + + G LL+ A+ ADSG Y C
Sbjct: 2354 EGQTLDLNCVVPGQSHAQVTWH--KRGGSLPVRHQTH----GSLLRLYQASPADSGEYVC 2407
Query: 88 IVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIY-CPTIDLYNWTA--- 143
V + VTI S VP + TV +S++ T+DL A
Sbjct: 2408 RVLGSSVPLEASVLVTIEPAGS---VPALGVTPTVRIESSSSQVAEGQTLDLNCLVAGQA 2464
Query: 144 --PLEWFKNCQALQGSRYRAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSVTAT 197
+ W K +L +R++ H S L + V D+G+Y C+ + + SV T
Sbjct: 2465 HAQVTWHKRGGSLP-ARHQVHGSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVT 2519
Score = 44.3 bits (103), Expect = 3e-04
Identities = 56/239 (23%), Positives = 93/239 (38%), Gaps = 20/239 (8%)
Query: 32 LIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCIVRS 91
L + C + +T+ WY + S+P++ + G L+ ADSG Y C V +
Sbjct: 2551 LDLNCLVASQAPHTITWY--KRGGSLPSRHQ----IVGSRLRIPQVTPADSGEYVCHVSN 2604
Query: 92 PTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCPTIDLYNWTAP-----LE 146
+R VTI S +VP + S + + T+DL A +
Sbjct: 2605 GAGSRETSLIVTIQGSGSS-HVPSVSPPIRIESSSP-TVVEGQTLDLNCVVARQPQAIIT 2662
Query: 147 WFKNCQALQGSRYRAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSVTATRSFTVKDEQ 206
W+K +L SR++ H S L + + D+G+Y C+ +N + S+ +V
Sbjct: 2663 WYKRGGSLP-SRHQTHGSHLRLHQMSVADSGEYVCRANNNIDALEASIV----ISVSPSA 2717
Query: 207 GFSLFPVIGAPAQNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQLNGTKITDFGEPR 265
G P P + E + + L + C G Q A V W G + + R
Sbjct: 2718 GSPSAPGSSMPIRIESSSSHVAEGETLDLN-CVVPG-QAHAQVTWHKRGGSLPSHHQTR 2774
Score = 40.4 bits (93), Expect = 0.004
Identities = 57/242 (23%), Positives = 91/242 (37%), Gaps = 37/242 (15%)
Query: 28 ENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTC 87
E + L + C G V WY + S+P + G L+ + ADSG Y C
Sbjct: 2064 EGQTLDLNCVVAGSAHAQVTWY--RRGGSLPPHTQ----VHGSRLRLPQVSPADSGEYVC 2117
Query: 88 IVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCP--------TIDLY 139
V + + + A++T+ + P Y + V GS + +I T+DL
Sbjct: 2118 RVENGSGPKE--ASITVSVLHGTHSGPSY---TPVPGSTRPIRIEPSSSHVAEGQTLDL- 2171
Query: 140 NWTAP------LEWFKNCQALQGSRYRAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYS 193
N P + W K +L +R++ H S L + V D+G+Y C + S
Sbjct: 2172 NCVVPGQAHAQVTWHKRGGSLP-ARHQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLEAS 2230
Query: 194 VTATRSFTVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQL 253
V T +V P+ ++ V G+ +L+C Q A V W
Sbjct: 2231 VLVTIEASVIPG------PIPPVRIESSSSTVAEGQTLDLSCVV----AGQAHAQVTWYK 2280
Query: 254 NG 255
G
Sbjct: 2281 RG 2282
Score = 39.7 bits (91), Expect = 0.007
Identities = 54/218 (24%), Positives = 92/218 (42%), Gaps = 24/218 (11%)
Query: 28 ENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTC 87
E + L ++C G+ V W+ N +P + + G LL+ + ADSG Y+C
Sbjct: 2840 EGQTLDLKCVVPGQAHAQVTWHKRGGN--LPARHQ----VHGPLLRLNQVSPADSGEYSC 2893
Query: 88 IVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIY-CPTIDLYNWTAP-- 144
V + VTI + S +P + + +S + T+DL N P
Sbjct: 2894 QVTGSSGTLEASVLVTI-EPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDL-NCVVPGQ 2951
Query: 145 ----LEWFKNCQALQGSRYRAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSVTATRSF 200
+ W+K +L +R++ H S L + V D+G+Y C+ +G A+ +
Sbjct: 2952 AHAQVTWYKRGGSLP-ARHQTHGSQLRLHLVSPADSGEYVCR---AASGPGPEQEASFTV 3007
Query: 201 TVKDEQGFSL---FPVIGAPAQNEIKEVEIGKNANLTC 235
TV +G S PVI + V+ G++A+ C
Sbjct: 3008 TVPPSEGSSYRLRSPVISIDPPS--STVQQGQDASFKC 3043
Score = 37.7 bits (86), Expect = 0.028
Identities = 46/184 (25%), Positives = 73/184 (39%), Gaps = 14/184 (7%)
Query: 21 SKQSWGLENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVA 80
S S E E L + C G+ V W+ + S+P+ + R G L+ + A
Sbjct: 2733 SSSSHVAEGETLDLNCVVPGQAHAQVTWH--KRGGSLPSHHQTR----GSRLRLHHVSPA 2786
Query: 81 DSGIYTCIVRSPTFNRTGYANVTIYKKQSDC-NVPDYLMYSTVSGSEKNSKIY-CPTIDL 138
DSG Y C V + VTI S +VP + +S++ T+DL
Sbjct: 2787 DSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDL 2846
Query: 139 Y-----NWTAPLEWFKNCQALQGSRYRAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYS 193
A + W K L +R++ H L ++ V D+G+Y+C+ + S
Sbjct: 2847 KCVVPGQAHAQVTWHKRGGNLP-ARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEAS 2905
Query: 194 VTAT 197
V T
Sbjct: 2906 VLVT 2909
Score = 37.0 bits (84), Expect = 0.048
Identities = 40/158 (25%), Positives = 63/158 (39%), Gaps = 23/158 (14%)
Query: 34 VRCPRQGKPSYTVDWYYSQTNKSIP--TQERNRVFASGQLLKFLPAAVADSGIYTCIVRS 91
+RC G P + W + + +P TQ+R++ G L F +D+G+Y C R+
Sbjct: 1696 LRCQVSGSPPHYFYWS-REDGRPVPSGTQQRHQ----GSELHFPSVQPSDAGVYICTCRN 1750
Query: 92 PTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCPTIDL-YNWTA------- 143
+ T A + + + S TV+ E+ S+ P D+ + TA
Sbjct: 1751 LHQSNTSRAELLVTEAPS--------KPITVTVEEQRSQSVRPGADVTFICTAKSKSPAY 1802
Query: 144 PLEWFKNCQALQGSRYRAHKSFLVIDNVMTEDAGDYTC 181
L W + +R L I NV DAG Y C
Sbjct: 1803 TLVWTRLHNGKLPTRAMDFNGILTIRNVQLSDAGTYVC 1840
Score = 37.0 bits (84), Expect = 0.048
Identities = 66/298 (22%), Positives = 108/298 (36%), Gaps = 50/298 (16%)
Query: 30 EALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCIV 89
E + ++C G P T W S+ S+P R A +LL F AA DSG Y C V
Sbjct: 3314 ETVQLQCLAHGTPPLTFQW--SRVGSSLP----GRATARNELLHFERAAPEDSGRYRCRV 3367
Query: 90 RSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCPTIDLYNWTAPLEWFK 149
+ + +A + + P L +++ + P ++ + A +E+
Sbjct: 3368 TNKVGSAEAFAQLLVQ------GPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHC 3421
Query: 150 NCQALQGSRYRAHK-------SFLVIDNVMTEDAGDYTCK--FIHNENGANYSVTATRSF 200
+ +G++ R K V D V+ D +C+ +I +G A+
Sbjct: 3422 AVPSDRGTQLRWFKEGGQLPPGHSVQDGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQL 3481
Query: 201 TVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQLNGTKITD 260
++ P + + ++ V +G C A Q V W +K+
Sbjct: 3482 VIQ------ALPSVLINIRTSVQTVVVGHAVEFECLALGDPKPQ----VTW----SKVGG 3527
Query: 261 FGEPRIQQEEGQNQSFSNGLACLDMVLRIADVKEEDLLLQYDCLALNLHGLRRHTVRL 318
P I Q G V+RIA V+ D QY C A N G + V L
Sbjct: 3528 HLRPGIVQSGG--------------VVRIAHVELAD-AGQYRCTATNAAGTTQSHVLL 3570
>gi|110431348 deleted in colorectal carcinoma [Homo sapiens]
Length = 1447
Score = 46.2 bits (108), Expect = 8e-05
Identities = 49/185 (26%), Positives = 85/185 (45%), Gaps = 24/185 (12%)
Query: 30 EALIVRCPRQGKPSYTVDWYYSQTNKS-IPTQERNRVFASG--QLLKFLPAAVADSGIYT 86
+ ++++C G+P T+ W +Q + + IP R V SG Q+ + P D GIY
Sbjct: 155 DTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPG---DIGIYR 211
Query: 87 CIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMY-----STVSGSEKNSKIYCPTIDLYNW 141
C R+P +RTG N + SD + L + + V+ K++ + C + +
Sbjct: 212 CSARNPASSRTG--NEAEVRILSDPGLHRQLYFLQRPSNVVAIEGKDAVLEC---CVSGY 266
Query: 142 TAP-LEWFKNCQALQ--GSRYR-AHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSVTAT 197
P W + + +Q +Y S L+I NV +D+G YTC + N +++A+
Sbjct: 267 PPPSFTWLRGEEVIQLRSKKYSLLGGSNLLISNVTDDDSGMYTCVVTYK----NENISAS 322
Query: 198 RSFTV 202
TV
Sbjct: 323 AELTV 327
Score = 31.6 bits (70), Expect = 2.0
Identities = 23/100 (23%), Positives = 36/100 (36%), Gaps = 3/100 (3%)
Query: 7 AILTILMYSTAAKFSKQSWGLENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVF 66
A LT+L+ + E+ + C GKP TV+W N +
Sbjct: 323 AELTVLVPPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNW---MKNGDVVIPSDYFQI 379
Query: 67 ASGQLLKFLPAAVADSGIYTCIVRSPTFNRTGYANVTIYK 106
G L+ L +D G Y C+ + N A + + K
Sbjct: 380 VGGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPK 419
>gi|62865621 toll-like receptor 10 precursor [Homo sapiens]
Length = 811
Score = 46.2 bits (108), Expect = 8e-05
Identities = 51/244 (20%), Positives = 94/244 (38%), Gaps = 34/244 (13%)
Query: 301 YDC-LALNLHGLRRHTVRLSRKNPIDHHSIYCIIAVCSVFLMLINVLVIILKMFWIEATL 359
Y C LNL G R V L H + C A +LI +V+I+ + +
Sbjct: 551 YTCEYPLNLRGTRLKDVHL--------HELSCNTA------LLIVTIVVIMLVLGLAVAF 596
Query: 360 LWRDIAKPYKTRNDGKLYDAYVVYPRNYKSSTDGASRVEHFV-----------HQILPDV 408
P+ R G+ + + + R F+ ++++P++
Sbjct: 597 CCLHFDLPWYLRMLGQCTQTWHRVRKTTQEQLKRNVRFHAFISYSEHDSLWVKNELIPNL 656
Query: 409 LENKCGYTLCIYGRDMLPGEDVVTAVETNIRKSRRHIFILTPQITHNKEFAYEQEVALHC 468
+ +C+Y PG+ + + + I KS + IF+L+P N+ YE A H
Sbjct: 657 EKEDGSILICLYESYFDPGKSISENIVSFIEKSYKSIFVLSPNFVQNEWCHYEFYFAHHN 716
Query: 469 ALIQNDAKVILIEMEALSELDMLQAEALQDSLQHLMKVQGTIKWREDHIANKRSLNSKFW 528
+N +ILI +E + L+ L++ + ++W +D R FW
Sbjct: 717 LFHENSDHIILILLE---PIPFYCIPTRYHKLKALLEKKAYLEWPKD-----RRKCGLFW 768
Query: 529 KHVR 532
++R
Sbjct: 769 ANLR 772
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.135 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,546,840
Number of Sequences: 37866
Number of extensions: 901118
Number of successful extensions: 3233
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 141
Number of HSP's that attempted gapping in prelim test: 2309
Number of HSP's gapped (non-prelim): 853
length of query: 556
length of database: 18,247,518
effective HSP length: 107
effective length of query: 449
effective length of database: 14,195,856
effective search space: 6373939344
effective search space used: 6373939344
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.