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Search of human proteins with 27886541
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27886541 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 2 isoform C [Homo sapiens]
(925 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27886541 nuclear factor of activated T-cells, cytoplasmic, ca... 1901 0.0
gi|27886539 nuclear factor of activated T-cells, cytoplasmic, ca... 1865 0.0
gi|209862843 nuclear factor of activated T-cells, cytoplasmic, c... 1773 0.0
gi|27502386 nuclear factor of activated T-cells, cytosolic compo... 612 e-175
gi|27502391 nuclear factor of activated T-cells, cytosolic compo... 585 e-167
gi|19923350 nuclear factor of activated T-cells, cytosolic compo... 580 e-165
gi|27502393 nuclear factor of activated T-cells, cytosolic compo... 525 e-149
gi|27886561 nuclear factor of activated T-cells, cytoplasmic, ca... 453 e-127
gi|27886559 nuclear factor of activated T-cells, cytoplasmic, ca... 453 e-127
gi|27886555 nuclear factor of activated T-cells, cytoplasmic, ca... 453 e-127
gi|4758804 nuclear factor of activated T-cells, cytoplasmic, cal... 453 e-127
gi|27886563 nuclear factor of activated T-cells, cytoplasmic, ca... 433 e-121
gi|209862845 nuclear factor of activated T-cells, cytoplasmic, c... 430 e-120
gi|27502388 nuclear factor of activated T-cells, cytosolic compo... 387 e-107
gi|27886520 nuclear factor of activated T-cells 5 isoform a [Hom... 221 2e-57
gi|5729945 nuclear factor of activated T-cells 5 isoform c [Homo... 221 2e-57
gi|164419746 nuclear factor of activated T-cells 5 isoform d [Ho... 221 2e-57
gi|164419744 nuclear factor of activated T-cells 5 isoform b [Ho... 221 2e-57
gi|27886524 nuclear factor of activated T-cells 5 isoform a [Hom... 221 2e-57
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 62 3e-09
gi|163965366 nascent polypeptide-associated complex alpha subuni... 59 2e-08
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 55 4e-07
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 54 7e-07
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 54 9e-07
gi|237757310 synaptojanin 1 isoform a [Homo sapiens] 53 1e-06
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 52 3e-06
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 52 3e-06
gi|237757308 synaptojanin 1 isoform b [Homo sapiens] 51 4e-06
gi|237757326 synaptojanin 1 isoform d [Homo sapiens] 51 6e-06
gi|41281612 zinc finger protein 828 [Homo sapiens] 51 6e-06
>gi|27886541 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 2 isoform C [Homo sapiens]
Length = 925
Score = 1901 bits (4925), Expect = 0.0
Identities = 925/925 (100%), Positives = 925/925 (100%)
Query: 1 MNAPERQPQPDGGDAPGHEPGGSPQDELDFSILFDYEYLNPNEEEPNAHKVASPPSGPAY 60
MNAPERQPQPDGGDAPGHEPGGSPQDELDFSILFDYEYLNPNEEEPNAHKVASPPSGPAY
Sbjct: 1 MNAPERQPQPDGGDAPGHEPGGSPQDELDFSILFDYEYLNPNEEEPNAHKVASPPSGPAY 60
Query: 61 PDDVLDYGLKPYSPLASLSGEPPGRFGEPDRVGPQKFLSAAKPAGASGLSPRIEITPSHE 120
PDDVLDYGLKPYSPLASLSGEPPGRFGEPDRVGPQKFLSAAKPAGASGLSPRIEITPSHE
Sbjct: 61 PDDVLDYGLKPYSPLASLSGEPPGRFGEPDRVGPQKFLSAAKPAGASGLSPRIEITPSHE 120
Query: 121 LIQAVGPLRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGYREPLCLSPASSGSSASFIS 180
LIQAVGPLRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGYREPLCLSPASSGSSASFIS
Sbjct: 121 LIQAVGPLRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGYREPLCLSPASSGSSASFIS 180
Query: 181 DTFSPYTSPCVSPNNGGPDDLCPQFQNIPAHYSPRTSPIMSPRTSLAEDSCLGRHSPVPR 240
DTFSPYTSPCVSPNNGGPDDLCPQFQNIPAHYSPRTSPIMSPRTSLAEDSCLGRHSPVPR
Sbjct: 181 DTFSPYTSPCVSPNNGGPDDLCPQFQNIPAHYSPRTSPIMSPRTSLAEDSCLGRHSPVPR 240
Query: 241 PASRSSSPGAKRRHSCAEALVALPPGASPQRSRSPSPQPSSHVAPQDHGSPAGYPPVAGS 300
PASRSSSPGAKRRHSCAEALVALPPGASPQRSRSPSPQPSSHVAPQDHGSPAGYPPVAGS
Sbjct: 241 PASRSSSPGAKRRHSCAEALVALPPGASPQRSRSPSPQPSSHVAPQDHGSPAGYPPVAGS 300
Query: 301 AVIMDALNSLATDSPCGIPPKMWKTSPDPSPVSAAPSKAGLPRHIYPAVEFLGPCEQGER 360
AVIMDALNSLATDSPCGIPPKMWKTSPDPSPVSAAPSKAGLPRHIYPAVEFLGPCEQGER
Sbjct: 301 AVIMDALNSLATDSPCGIPPKMWKTSPDPSPVSAAPSKAGLPRHIYPAVEFLGPCEQGER 360
Query: 361 RNSAPESILLVPPTWPKPLVPAIPICSIPVTASLPPLEWPLSSQSGSYELRIEVQPKPHH 420
RNSAPESILLVPPTWPKPLVPAIPICSIPVTASLPPLEWPLSSQSGSYELRIEVQPKPHH
Sbjct: 361 RNSAPESILLVPPTWPKPLVPAIPICSIPVTASLPPLEWPLSSQSGSYELRIEVQPKPHH 420
Query: 421 RAHYETEGSRGAVKAPTGGHPVVQLHGYMENKPLGLQIFIGTADERILKPHAFYQVHRIT 480
RAHYETEGSRGAVKAPTGGHPVVQLHGYMENKPLGLQIFIGTADERILKPHAFYQVHRIT
Sbjct: 421 RAHYETEGSRGAVKAPTGGHPVVQLHGYMENKPLGLQIFIGTADERILKPHAFYQVHRIT 480
Query: 481 GKTVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDCAGILKLRNADIELRKGETDIGRKNT 540
GKTVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDCAGILKLRNADIELRKGETDIGRKNT
Sbjct: 481 GKTVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDCAGILKLRNADIELRKGETDIGRKNT 540
Query: 541 RVRLVFRVHIPESSGRIVSLQTASNPIECSQRSAHELPMVERQDTDSCLVYGGQQMILTG 600
RVRLVFRVHIPESSGRIVSLQTASNPIECSQRSAHELPMVERQDTDSCLVYGGQQMILTG
Sbjct: 541 RVRLVFRVHIPESSGRIVSLQTASNPIECSQRSAHELPMVERQDTDSCLVYGGQQMILTG 600
Query: 601 QNFTSESKVVFTEKTTDGQQIWEMEATVDKDKSQPNMLFVEIPEYRNKHIRTPVKVNFYV 660
QNFTSESKVVFTEKTTDGQQIWEMEATVDKDKSQPNMLFVEIPEYRNKHIRTPVKVNFYV
Sbjct: 601 QNFTSESKVVFTEKTTDGQQIWEMEATVDKDKSQPNMLFVEIPEYRNKHIRTPVKVNFYV 660
Query: 661 INGKRKRSQPQHFTYHPVPAIKTEPTDEYDPTLICSPTHGGLGSQPYYPQHPMVAESPSC 720
INGKRKRSQPQHFTYHPVPAIKTEPTDEYDPTLICSPTHGGLGSQPYYPQHPMVAESPSC
Sbjct: 661 INGKRKRSQPQHFTYHPVPAIKTEPTDEYDPTLICSPTHGGLGSQPYYPQHPMVAESPSC 720
Query: 721 LVATMAPCQQFRTGLSSPDARYQQQNPAAVLYQRSKSLSPSLLGYQQPALMAAPLSLADA 780
LVATMAPCQQFRTGLSSPDARYQQQNPAAVLYQRSKSLSPSLLGYQQPALMAAPLSLADA
Sbjct: 721 LVATMAPCQQFRTGLSSPDARYQQQNPAAVLYQRSKSLSPSLLGYQQPALMAAPLSLADA 780
Query: 781 HRSVLVHAGSQGQSSALLHPSPTNQQASPVIHYSPTNQQLRCGSHQEFQHIMYCENFAPG 840
HRSVLVHAGSQGQSSALLHPSPTNQQASPVIHYSPTNQQLRCGSHQEFQHIMYCENFAPG
Sbjct: 781 HRSVLVHAGSQGQSSALLHPSPTNQQASPVIHYSPTNQQLRCGSHQEFQHIMYCENFAPG 840
Query: 841 TTRPGPPPVSQGQRLSPGSYPTVIQQQNATSQRAAKNGPPVSDQKEVLPAGVTIKQEQNL 900
TTRPGPPPVSQGQRLSPGSYPTVIQQQNATSQRAAKNGPPVSDQKEVLPAGVTIKQEQNL
Sbjct: 841 TTRPGPPPVSQGQRLSPGSYPTVIQQQNATSQRAAKNGPPVSDQKEVLPAGVTIKQEQNL 900
Query: 901 DQTYLDDVNEIIRKEFSGPPARNQT 925
DQTYLDDVNEIIRKEFSGPPARNQT
Sbjct: 901 DQTYLDDVNEIIRKEFSGPPARNQT 925
>gi|27886539 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 2 isoform B [Homo sapiens]
Length = 921
Score = 1865 bits (4832), Expect = 0.0
Identities = 907/907 (100%), Positives = 907/907 (100%)
Query: 1 MNAPERQPQPDGGDAPGHEPGGSPQDELDFSILFDYEYLNPNEEEPNAHKVASPPSGPAY 60
MNAPERQPQPDGGDAPGHEPGGSPQDELDFSILFDYEYLNPNEEEPNAHKVASPPSGPAY
Sbjct: 1 MNAPERQPQPDGGDAPGHEPGGSPQDELDFSILFDYEYLNPNEEEPNAHKVASPPSGPAY 60
Query: 61 PDDVLDYGLKPYSPLASLSGEPPGRFGEPDRVGPQKFLSAAKPAGASGLSPRIEITPSHE 120
PDDVLDYGLKPYSPLASLSGEPPGRFGEPDRVGPQKFLSAAKPAGASGLSPRIEITPSHE
Sbjct: 61 PDDVLDYGLKPYSPLASLSGEPPGRFGEPDRVGPQKFLSAAKPAGASGLSPRIEITPSHE 120
Query: 121 LIQAVGPLRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGYREPLCLSPASSGSSASFIS 180
LIQAVGPLRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGYREPLCLSPASSGSSASFIS
Sbjct: 121 LIQAVGPLRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGYREPLCLSPASSGSSASFIS 180
Query: 181 DTFSPYTSPCVSPNNGGPDDLCPQFQNIPAHYSPRTSPIMSPRTSLAEDSCLGRHSPVPR 240
DTFSPYTSPCVSPNNGGPDDLCPQFQNIPAHYSPRTSPIMSPRTSLAEDSCLGRHSPVPR
Sbjct: 181 DTFSPYTSPCVSPNNGGPDDLCPQFQNIPAHYSPRTSPIMSPRTSLAEDSCLGRHSPVPR 240
Query: 241 PASRSSSPGAKRRHSCAEALVALPPGASPQRSRSPSPQPSSHVAPQDHGSPAGYPPVAGS 300
PASRSSSPGAKRRHSCAEALVALPPGASPQRSRSPSPQPSSHVAPQDHGSPAGYPPVAGS
Sbjct: 241 PASRSSSPGAKRRHSCAEALVALPPGASPQRSRSPSPQPSSHVAPQDHGSPAGYPPVAGS 300
Query: 301 AVIMDALNSLATDSPCGIPPKMWKTSPDPSPVSAAPSKAGLPRHIYPAVEFLGPCEQGER 360
AVIMDALNSLATDSPCGIPPKMWKTSPDPSPVSAAPSKAGLPRHIYPAVEFLGPCEQGER
Sbjct: 301 AVIMDALNSLATDSPCGIPPKMWKTSPDPSPVSAAPSKAGLPRHIYPAVEFLGPCEQGER 360
Query: 361 RNSAPESILLVPPTWPKPLVPAIPICSIPVTASLPPLEWPLSSQSGSYELRIEVQPKPHH 420
RNSAPESILLVPPTWPKPLVPAIPICSIPVTASLPPLEWPLSSQSGSYELRIEVQPKPHH
Sbjct: 361 RNSAPESILLVPPTWPKPLVPAIPICSIPVTASLPPLEWPLSSQSGSYELRIEVQPKPHH 420
Query: 421 RAHYETEGSRGAVKAPTGGHPVVQLHGYMENKPLGLQIFIGTADERILKPHAFYQVHRIT 480
RAHYETEGSRGAVKAPTGGHPVVQLHGYMENKPLGLQIFIGTADERILKPHAFYQVHRIT
Sbjct: 421 RAHYETEGSRGAVKAPTGGHPVVQLHGYMENKPLGLQIFIGTADERILKPHAFYQVHRIT 480
Query: 481 GKTVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDCAGILKLRNADIELRKGETDIGRKNT 540
GKTVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDCAGILKLRNADIELRKGETDIGRKNT
Sbjct: 481 GKTVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDCAGILKLRNADIELRKGETDIGRKNT 540
Query: 541 RVRLVFRVHIPESSGRIVSLQTASNPIECSQRSAHELPMVERQDTDSCLVYGGQQMILTG 600
RVRLVFRVHIPESSGRIVSLQTASNPIECSQRSAHELPMVERQDTDSCLVYGGQQMILTG
Sbjct: 541 RVRLVFRVHIPESSGRIVSLQTASNPIECSQRSAHELPMVERQDTDSCLVYGGQQMILTG 600
Query: 601 QNFTSESKVVFTEKTTDGQQIWEMEATVDKDKSQPNMLFVEIPEYRNKHIRTPVKVNFYV 660
QNFTSESKVVFTEKTTDGQQIWEMEATVDKDKSQPNMLFVEIPEYRNKHIRTPVKVNFYV
Sbjct: 601 QNFTSESKVVFTEKTTDGQQIWEMEATVDKDKSQPNMLFVEIPEYRNKHIRTPVKVNFYV 660
Query: 661 INGKRKRSQPQHFTYHPVPAIKTEPTDEYDPTLICSPTHGGLGSQPYYPQHPMVAESPSC 720
INGKRKRSQPQHFTYHPVPAIKTEPTDEYDPTLICSPTHGGLGSQPYYPQHPMVAESPSC
Sbjct: 661 INGKRKRSQPQHFTYHPVPAIKTEPTDEYDPTLICSPTHGGLGSQPYYPQHPMVAESPSC 720
Query: 721 LVATMAPCQQFRTGLSSPDARYQQQNPAAVLYQRSKSLSPSLLGYQQPALMAAPLSLADA 780
LVATMAPCQQFRTGLSSPDARYQQQNPAAVLYQRSKSLSPSLLGYQQPALMAAPLSLADA
Sbjct: 721 LVATMAPCQQFRTGLSSPDARYQQQNPAAVLYQRSKSLSPSLLGYQQPALMAAPLSLADA 780
Query: 781 HRSVLVHAGSQGQSSALLHPSPTNQQASPVIHYSPTNQQLRCGSHQEFQHIMYCENFAPG 840
HRSVLVHAGSQGQSSALLHPSPTNQQASPVIHYSPTNQQLRCGSHQEFQHIMYCENFAPG
Sbjct: 781 HRSVLVHAGSQGQSSALLHPSPTNQQASPVIHYSPTNQQLRCGSHQEFQHIMYCENFAPG 840
Query: 841 TTRPGPPPVSQGQRLSPGSYPTVIQQQNATSQRAAKNGPPVSDQKEVLPAGVTIKQEQNL 900
TTRPGPPPVSQGQRLSPGSYPTVIQQQNATSQRAAKNGPPVSDQKEVLPAGVTIKQEQNL
Sbjct: 841 TTRPGPPPVSQGQRLSPGSYPTVIQQQNATSQRAAKNGPPVSDQKEVLPAGVTIKQEQNL 900
Query: 901 DQTYLDD 907
DQTYLDD
Sbjct: 901 DQTYLDD 907
>gi|209862843 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 2 isoform D [Homo sapiens]
Length = 901
Score = 1773 bits (4592), Expect = 0.0
Identities = 864/866 (99%), Positives = 866/866 (100%)
Query: 42 NEEEPNAHKVASPPSGPAYPDDVLDYGLKPYSPLASLSGEPPGRFGEPDRVGPQKFLSAA 101
++EEPNAHKVASPPSGPAYPDDVLDYGLKPYSPLASLSGEPPGRFGEPDRVGPQKFLSAA
Sbjct: 22 DQEEPNAHKVASPPSGPAYPDDVLDYGLKPYSPLASLSGEPPGRFGEPDRVGPQKFLSAA 81
Query: 102 KPAGASGLSPRIEITPSHELIQAVGPLRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGY 161
KPAGASGLSPRIEITPSHELIQAVGPLRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGY
Sbjct: 82 KPAGASGLSPRIEITPSHELIQAVGPLRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGY 141
Query: 162 REPLCLSPASSGSSASFISDTFSPYTSPCVSPNNGGPDDLCPQFQNIPAHYSPRTSPIMS 221
REPLCLSPASSGSSASFISDTFSPYTSPCVSPNNGGPDDLCPQFQNIPAHYSPRTSPIMS
Sbjct: 142 REPLCLSPASSGSSASFISDTFSPYTSPCVSPNNGGPDDLCPQFQNIPAHYSPRTSPIMS 201
Query: 222 PRTSLAEDSCLGRHSPVPRPASRSSSPGAKRRHSCAEALVALPPGASPQRSRSPSPQPSS 281
PRTSLAEDSCLGRHSPVPRPASRSSSPGAKRRHSCAEALVALPPGASPQRSRSPSPQPSS
Sbjct: 202 PRTSLAEDSCLGRHSPVPRPASRSSSPGAKRRHSCAEALVALPPGASPQRSRSPSPQPSS 261
Query: 282 HVAPQDHGSPAGYPPVAGSAVIMDALNSLATDSPCGIPPKMWKTSPDPSPVSAAPSKAGL 341
HVAPQDHGSPAGYPPVAGSAVIMDALNSLATDSPCGIPPKMWKTSPDPSPVSAAPSKAGL
Sbjct: 262 HVAPQDHGSPAGYPPVAGSAVIMDALNSLATDSPCGIPPKMWKTSPDPSPVSAAPSKAGL 321
Query: 342 PRHIYPAVEFLGPCEQGERRNSAPESILLVPPTWPKPLVPAIPICSIPVTASLPPLEWPL 401
PRHIYPAVEFLGPCEQGERRNSAPESILLVPPTWPKPLVPAIPICSIPVTASLPPLEWPL
Sbjct: 322 PRHIYPAVEFLGPCEQGERRNSAPESILLVPPTWPKPLVPAIPICSIPVTASLPPLEWPL 381
Query: 402 SSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVVQLHGYMENKPLGLQIFIG 461
SSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVVQLHGYMENKPLGLQIFIG
Sbjct: 382 SSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVVQLHGYMENKPLGLQIFIG 441
Query: 462 TADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDCAGILKL 521
TADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDCAGILKL
Sbjct: 442 TADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDCAGILKL 501
Query: 522 RNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIVSLQTASNPIECSQRSAHELPMVE 581
RNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIVSLQTASNPIECSQRSAHELPMVE
Sbjct: 502 RNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIVSLQTASNPIECSQRSAHELPMVE 561
Query: 582 RQDTDSCLVYGGQQMILTGQNFTSESKVVFTEKTTDGQQIWEMEATVDKDKSQPNMLFVE 641
RQDTDSCLVYGGQQMILTGQNFTSESKVVFTEKTTDGQQIWEMEATVDKDKSQPNMLFVE
Sbjct: 562 RQDTDSCLVYGGQQMILTGQNFTSESKVVFTEKTTDGQQIWEMEATVDKDKSQPNMLFVE 621
Query: 642 IPEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHPVPAIKTEPTDEYDPTLICSPTHGG 701
IPEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHPVPAIKTEPTDEYDPTLICSPTHGG
Sbjct: 622 IPEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHPVPAIKTEPTDEYDPTLICSPTHGG 681
Query: 702 LGSQPYYPQHPMVAESPSCLVATMAPCQQFRTGLSSPDARYQQQNPAAVLYQRSKSLSPS 761
LGSQPYYPQHPMVAESPSCLVATMAPCQQFRTGLSSPDARYQQQNPAAVLYQRSKSLSPS
Sbjct: 682 LGSQPYYPQHPMVAESPSCLVATMAPCQQFRTGLSSPDARYQQQNPAAVLYQRSKSLSPS 741
Query: 762 LLGYQQPALMAAPLSLADAHRSVLVHAGSQGQSSALLHPSPTNQQASPVIHYSPTNQQLR 821
LLGYQQPALMAAPLSLADAHRSVLVHAGSQGQSSALLHPSPTNQQASPVIHYSPTNQQLR
Sbjct: 742 LLGYQQPALMAAPLSLADAHRSVLVHAGSQGQSSALLHPSPTNQQASPVIHYSPTNQQLR 801
Query: 822 CGSHQEFQHIMYCENFAPGTTRPGPPPVSQGQRLSPGSYPTVIQQQNATSQRAAKNGPPV 881
CGSHQEFQHIMYCENFAPGTTRPGPPPVSQGQRLSPGSYPTVIQQQNATSQRAAKNGPPV
Sbjct: 802 CGSHQEFQHIMYCENFAPGTTRPGPPPVSQGQRLSPGSYPTVIQQQNATSQRAAKNGPPV 861
Query: 882 SDQKEVLPAGVTIKQEQNLDQTYLDD 907
SDQKEVLPAGVTIKQEQNLDQTYLDD
Sbjct: 862 SDQKEVLPAGVTIKQEQNLDQTYLDD 887
>gi|27502386 nuclear factor of activated T-cells, cytosolic
component 1 isoform C [Homo sapiens]
Length = 930
Score = 612 bits (1578), Expect = e-175
Identities = 418/974 (42%), Positives = 530/974 (54%), Gaps = 130/974 (13%)
Query: 22 GSPQDELDFSILFDYEYLNPNEEE--PNAHKVASPPSGPAYPDDVLD-------YGLKPY 72
G E DF LF++ + P + AS PA P + L+
Sbjct: 3 GLEDQEFDFEFLFEFNQRDEGAAAAAPEHYGYASSNVSPALPLPTAHSTLPAPCHNLQTS 62
Query: 73 SPLASLSGEPPGRFGEPDRVGPQK-FLSAA--KPAGASGL-SPRIEITPS----HELIQA 124
+P + P +G GP FLS+ +P GA L SPRIEIT H Q
Sbjct: 63 TPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQF 122
Query: 125 VGPLRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGYREPLCLSPASSGSSAS------- 177
+ + D ++ P TL +P E YR+P CLSPASS SS S
Sbjct: 123 FHDVEVEDVLPSSKRSPSTA-------TLSLPSLEAYRDPSCLSPASSLSSRSCNSEASS 175
Query: 178 --------FISDTFSPYTSPCVSPNNGGPDDLCPQFQNIPAHY-SPRTSPIMSPRTSLAE 228
+ S SP+ SPCVSP P++ P+ SPR SP SPR S+ E
Sbjct: 176 YESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTE 235
Query: 229 DSCLGRHSPVPRPASRSSSPGAKRRHSCAEALVALPPGASPQRSRSPSPQPSSHVAPQDH 288
+S LG S SR +SP KR++S L P SP S +PSP S V+ D
Sbjct: 236 ESWLGARS------SRPASPCNKRKYS----LNGRQPPYSPHHSPTPSPHGSPRVSVTDD 285
Query: 289 GSPAGYPPVAGSAVIMDALNSLATDSPC----GIPPKMWKTSPDPSP------------V 332
S G S+ I+ A+N+L TDS G+P K KT+ + P +
Sbjct: 286 -SWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDL 344
Query: 333 SAAPSKAGLPRHIYPAVEFLGPCEQGERRNSAPESILLVPP---TW--PKPLVPAIPICS 387
+ P A Y + + + R+ + L VP W PKPL P +
Sbjct: 345 GSPPPPADFAPEDYSSFQHI-------RKGGFCDQYLAVPQHPYQWAKPKPLSP-----T 392
Query: 388 IPVTASLPPLEWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVVQLHG 447
++ +LP L+W L S SG YELRIEVQPK HHRAHYETEGSRGAVKA GGHP+VQLHG
Sbjct: 393 SYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHG 452
Query: 448 YMENKPLGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPLEPKN 507
Y+EN+PL LQ+FIGTAD+R+L+PHAFYQVHRITGKTV+TTS+E I+ NTKVLEIPL P+N
Sbjct: 453 YLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPEN 512
Query: 508 NMRATIDCAGILKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIVSLQTASNPI 567
+MRA IDCAGILKLRN+DIELRKGETDIGRKNTRVRLVFRVH+P+ SGR +SLQ ASNPI
Sbjct: 513 SMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPI 572
Query: 568 ECSQRSAHELPMVERQDTDSCLVYGGQQMILTGQNFTSESKVVFTEKTTDGQQIWEMEAT 627
ECSQRSA ELP+VE+Q TDS V GG++M+L+G NF +SKV+F EK DG +WEMEA
Sbjct: 573 ECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAK 632
Query: 628 VDKDKSQPNMLFVEIPEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHP--VPAIKTEP 685
D+D +PN L VEIP +RN+ I +PV V+FYV NGKRKRSQ Q FTY P VP IKTEP
Sbjct: 633 TDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEP 692
Query: 686 TDEYDPTLICSPTHGGLG--SQPYYPQHPMVAESP-SCLVATMAPCQQFRTGL-SSPDAR 741
TD+Y+P C P GL +PYY Q + P SCLVA PC Q T + ++P
Sbjct: 693 TDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVS 752
Query: 742 YQQQNPAAVLYQRS-KSLSPSLLGYQQPALMAAPLSLADAHRSVLVHAGSQGQSSALLHP 800
+ + + Y + S LG QPA A ++ D R V H GS GQ L P
Sbjct: 753 PKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAP--AVQDVPRPVATHPGSPGQPPPALLP 810
Query: 801 ----SPTNQQASPVIHYS-----------PTNQQLRCGSHQEFQHIMYCENFA-PGTTRP 844
+P + P + +S P Q+ C + C P T RP
Sbjct: 811 QQVSAPPSSSCPPGLEHSLCPSSPSPPLPPATQEPTC--------LQPCSPACPPATGRP 862
Query: 845 GPPPVSQGQRLSPGSYPTVIQQQNATSQRAAKNGPPVSDQKEVLPAGVTIKQE-QNLDQT 903
P + + SP + P ++ + + ++G P + P VT+K+E + LDQ
Sbjct: 863 QHLPSTVRRDESPTAGPRLLPEVH-------EDGSP-----NLAPIPVTVKREPEELDQL 910
Query: 904 YLDDVNEIIRKEFS 917
YLDDVNEIIR + S
Sbjct: 911 YLDDVNEIIRNDLS 924
>gi|27502391 nuclear factor of activated T-cells, cytosolic
component 1 isoform E [Homo sapiens]
Length = 812
Score = 585 bits (1507), Expect = e-167
Identities = 382/840 (45%), Positives = 474/840 (56%), Gaps = 93/840 (11%)
Query: 22 GSPQDELDFSILFDYEYLNPNEEE--PNAHKVASPPSGPAYPDDVLD-------YGLKPY 72
G E DF LF++ + P + AS PA P + L+
Sbjct: 3 GLEDQEFDFEFLFEFNQRDEGAAAAAPEHYGYASSNVSPALPLPTAHSTLPAPCHNLQTS 62
Query: 73 SPLASLSGEPPGRFGEPDRVGPQK-FLSAA--KPAGASGL-SPRIEITPS----HELIQA 124
+P + P +G GP FLS+ +P GA L SPRIEIT H Q
Sbjct: 63 TPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQF 122
Query: 125 VGPLRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGYREPLCLSPASSGSSAS------- 177
+ + D ++ P TL +P E YR+P CLSPASS SS S
Sbjct: 123 FHDVEVEDVLPSSKRSPSTA-------TLSLPSLEAYRDPSCLSPASSLSSRSCNSEASS 175
Query: 178 --------FISDTFSPYTSPCVSPNNGGPDDLCPQFQNIPAHY-SPRTSPIMSPRTSLAE 228
+ S SP+ SPCVSP P++ P+ SPR SP SPR S+ E
Sbjct: 176 YESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTE 235
Query: 229 DSCLGRHSPVPRPASRSSSPGAKRRHSCAEALVALPPGASPQRSRSPSPQPSSHVAPQDH 288
+S LG S SR +SP KR++S L P SP S +PSP S V+ D
Sbjct: 236 ESWLGARS------SRPASPCNKRKYS----LNGRQPPYSPHHSPTPSPHGSPRVSVTDD 285
Query: 289 GSPAGYPPVAGSAVIMDALNSLATDSPC----GIPPKMWKTSPDPSP------------V 332
S G S+ I+ A+N+L TDS G+P K KT+ + P +
Sbjct: 286 -SWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDL 344
Query: 333 SAAPSKAGLPRHIYPAVEFLGPCEQGERRNSAPESILLVPP---TW--PKPLVPAIPICS 387
+ P A Y + + + R+ + L VP W PKPL P +
Sbjct: 345 GSPPPPADFAPEDYSSFQHI-------RKGGFCDQYLAVPQHPYQWAKPKPLSP-----T 392
Query: 388 IPVTASLPPLEWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVVQLHG 447
++ +LP L+W L S SG YELRIEVQPK HHRAHYETEGSRGAVKA GGHP+VQLHG
Sbjct: 393 SYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHG 452
Query: 448 YMENKPLGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPLEPKN 507
Y+EN+PL LQ+FIGTAD+R+L+PHAFYQVHRITGKTV+TTS+E I+ NTKVLEIPL P+N
Sbjct: 453 YLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPEN 512
Query: 508 NMRATIDCAGILKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIVSLQTASNPI 567
+MRA IDCAGILKLRN+DIELRKGETDIGRKNTRVRLVFRVH+P+ SGR +SLQ ASNPI
Sbjct: 513 SMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPI 572
Query: 568 ECSQRSAHELPMVERQDTDSCLVYGGQQMILTGQNFTSESKVVFTEKTTDGQQIWEMEAT 627
ECSQRSA ELP+VE+Q TDS V GG++M+L+G NF +SKV+F EK DG +WEMEA
Sbjct: 573 ECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAK 632
Query: 628 VDKDKSQPNMLFVEIPEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHP--VPAIKTEP 685
D+D +PN L VEIP +RN+ I +PV V+FYV NGKRKRSQ Q FTY P VP IKTEP
Sbjct: 633 TDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEP 692
Query: 686 TDEYDPTLICSPTHGGLG--SQPYYPQHPMVAESP-SCLVATMAPCQQFRTGL-SSPDAR 741
TD+Y+P C P GL +PYY Q + P SCLVA PC Q T + ++P
Sbjct: 693 TDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVS 752
Query: 742 YQQQNPAAVLYQRS-KSLSPSLLGYQQPALMAAPLSLADAHRSVLVHAGSQGQSSALLHP 800
+ + + Y + S LG QPA A ++ D R V H GS GQ L P
Sbjct: 753 PKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAP--AVQDVPRPVATHPGSPGQPPPALLP 810
>gi|19923350 nuclear factor of activated T-cells, cytosolic
component 1 isoform B [Homo sapiens]
Length = 825
Score = 580 bits (1495), Expect = e-165
Identities = 378/837 (45%), Positives = 472/837 (56%), Gaps = 94/837 (11%)
Query: 16 PGHEPGGSPQDELDFSILFDYEYLNPNEEEPNAHKVASPPSGPAYPDDVLDYGLKPYSPL 75
P GG+ + + + ++P P AH P + L+ +P
Sbjct: 29 PAPRAGGTMKSAEEEHYGYASSNVSPALPLPTAHSTLPAPC----------HNLQTSTPG 78
Query: 76 ASLSGEPPGRFGEPDRVGPQK-FLSAA--KPAGASGL-SPRIEITPS----HELIQAVGP 127
+ P +G GP FLS+ +P GA L SPRIEIT H Q
Sbjct: 79 IIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHD 138
Query: 128 LRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGYREPLCLSPASSGSSAS---------- 177
+ + D ++ P TL +P E YR+P CLSPASS SS S
Sbjct: 139 VEVEDVLPSSKRSPSTA-------TLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYES 191
Query: 178 -----FISDTFSPYTSPCVSPNNGGPDDLCPQFQNIPAHY-SPRTSPIMSPRTSLAEDSC 231
+ S SP+ SPCVSP P++ P+ SPR SP SPR S+ E+S
Sbjct: 192 NYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESW 251
Query: 232 LGRHSPVPRPASRSSSPGAKRRHSCAEALVALPPGASPQRSRSPSPQPSSHVAPQDHGSP 291
LG S SR +SP KR++S L P SP S +PSP S V+ D S
Sbjct: 252 LGARS------SRPASPCNKRKYS----LNGRQPPYSPHHSPTPSPHGSPRVSVTDD-SW 300
Query: 292 AGYPPVAGSAVIMDALNSLATDSPC----GIPPKMWKTSPDPSP------------VSAA 335
G S+ I+ A+N+L TDS G+P K KT+ + P + +
Sbjct: 301 LGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSP 360
Query: 336 PSKAGLPRHIYPAVEFLGPCEQGERRNSAPESILLVPP---TW--PKPLVPAIPICSIPV 390
P A Y + + + R+ + L VP W PKPL P + +
Sbjct: 361 PPPADFAPEDYSSFQHI-------RKGGFCDQYLAVPQHPYQWAKPKPLSP-----TSYM 408
Query: 391 TASLPPLEWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVVQLHGYME 450
+ +LP L+W L S SG YELRIEVQPK HHRAHYETEGSRGAVKA GGHP+VQLHGY+E
Sbjct: 409 SPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLE 468
Query: 451 NKPLGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPLEPKNNMR 510
N+PL LQ+FIGTAD+R+L+PHAFYQVHRITGKTV+TTS+E I+ NTKVLEIPL P+N+MR
Sbjct: 469 NEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMR 528
Query: 511 ATIDCAGILKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIVSLQTASNPIECS 570
A IDCAGILKLRN+DIELRKGETDIGRKNTRVRLVFRVH+P+ SGR +SLQ ASNPIECS
Sbjct: 529 AVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECS 588
Query: 571 QRSAHELPMVERQDTDSCLVYGGQQMILTGQNFTSESKVVFTEKTTDGQQIWEMEATVDK 630
QRSA ELP+VE+Q TDS V GG++M+L+G NF +SKV+F EK DG +WEMEA D+
Sbjct: 589 QRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDR 648
Query: 631 DKSQPNMLFVEIPEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHP--VPAIKTEPTDE 688
D +PN L VEIP +RN+ I +PV V+FYV NGKRKRSQ Q FTY P VP IKTEPTD+
Sbjct: 649 DLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDD 708
Query: 689 YDPTLICSPTHGGLG--SQPYYPQHPMVAESP-SCLVATMAPCQQFRTGL-SSPDARYQQ 744
Y+P C P GL +PYY Q + P SCLVA PC Q T + ++P +
Sbjct: 709 YEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKL 768
Query: 745 QNPAAVLYQRS-KSLSPSLLGYQQPALMAAPLSLADAHRSVLVHAGSQGQSSALLHP 800
+ + Y + S LG QPA A ++ D R V H GS GQ L P
Sbjct: 769 HDLSPAAYTKGVASPGHCHLGLPQPAGEAP--AVQDVPRPVATHPGSPGQPPPALLP 823
>gi|27502393 nuclear factor of activated T-cells, cytosolic
component 1 isoform A [Homo sapiens]
Length = 716
Score = 525 bits (1352), Expect = e-149
Identities = 330/707 (46%), Positives = 411/707 (58%), Gaps = 85/707 (12%)
Query: 16 PGHEPGGSPQDELDFSILFDYEYLNPNEEEPNAHKVASPPSGPAYPDDVLDYGLKPYSPL 75
P GG+ + + + ++P P AH P + L+ +P
Sbjct: 29 PAPRAGGTMKSAEEEHYGYASSNVSPALPLPTAHSTLPAPC----------HNLQTSTPG 78
Query: 76 ASLSGEPPGRFGEPDRVGPQK-FLSAA--KPAGASGL-SPRIEITPS----HELIQAVGP 127
+ P +G GP FLS+ +P GA L SPRIEIT H Q
Sbjct: 79 IIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHD 138
Query: 128 LRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGYREPLCLSPASSGSSAS---------- 177
+ + D ++ P TL +P E YR+P CLSPASS SS S
Sbjct: 139 VEVEDVLPSSKRSPSTA-------TLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYES 191
Query: 178 -----FISDTFSPYTSPCVSPNNGGPDDLCPQFQNIPAHY-SPRTSPIMSPRTSLAEDSC 231
+ S SP+ SPCVSP P++ P+ SPR SP SPR S+ E+S
Sbjct: 192 NYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESW 251
Query: 232 LGRHSPVPRPASRSSSPGAKRRHSCAEALVALPPGASPQRSRSPSPQPSSHVAPQDHGSP 291
LG S SR +SP KR++S L P SP S +PSP S V+ D S
Sbjct: 252 LGARS------SRPASPCNKRKYS----LNGRQPPYSPHHSPTPSPHGSPRVSVTDD-SW 300
Query: 292 AGYPPVAGSAVIMDALNSLATDSPC----GIPPKMWKTSPDPSP------------VSAA 335
G S+ I+ A+N+L TDS G+P K KT+ + P + +
Sbjct: 301 LGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSP 360
Query: 336 PSKAGLPRHIYPAVEFLGPCEQGERRNSAPESILLVPP---TW--PKPLVPAIPICSIPV 390
P A Y + + + R+ + L VP W PKPL P + +
Sbjct: 361 PPPADFAPEDYSSFQHI-------RKGGFCDQYLAVPQHPYQWAKPKPLSP-----TSYM 408
Query: 391 TASLPPLEWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVVQLHGYME 450
+ +LP L+W L S SG YELRIEVQPK HHRAHYETEGSRGAVKA GGHP+VQLHGY+E
Sbjct: 409 SPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLE 468
Query: 451 NKPLGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPLEPKNNMR 510
N+PL LQ+FIGTAD+R+L+PHAFYQVHRITGKTV+TTS+E I+ NTKVLEIPL P+N+MR
Sbjct: 469 NEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMR 528
Query: 511 ATIDCAGILKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIVSLQTASNPIECS 570
A IDCAGILKLRN+DIELRKGETDIGRKNTRVRLVFRVH+P+ SGR +SLQ ASNPIECS
Sbjct: 529 AVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECS 588
Query: 571 QRSAHELPMVERQDTDSCLVYGGQQMILTGQNFTSESKVVFTEKTTDGQQIWEMEATVDK 630
QRSA ELP+VE+Q TDS V GG++M+L+G NF +SKV+F EK DG +WEMEA D+
Sbjct: 589 QRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDR 648
Query: 631 DKSQPNMLFVEIPEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHP 677
D +PN L VEIP +RN+ I +PV V+FYV NGKRKRSQ Q FTY P
Sbjct: 649 DLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLP 695
>gi|27886561 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 3 isoform 1 [Homo sapiens]
Length = 1075
Score = 453 bits (1166), Expect = e-127
Identities = 346/891 (38%), Positives = 452/891 (50%), Gaps = 116/891 (13%)
Query: 26 DELDFSILFDYEYL--------NPNEEEPN------AHKVASPPSGPAYPDDVLDYGLKP 71
DELDF ++F + P + EP+ V PPS P + +GL
Sbjct: 10 DELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPLCLPHHGLPS 69
Query: 72 YSPLASLSGEPPGR--FGEPDRVGPQKF--LSAAKPAGASGLSPRIEITP----SHELIQ 123
+S + S S + + + K+ L KP P I+IT H+ +
Sbjct: 70 HSSVLSPSFQLQSHKNYEGTCEIPESKYSPLGGPKPFEC----PSIQITSISPNCHQELD 125
Query: 124 AVGPLRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGYREP-LCLSPASSGSSASFISDT 182
A + L + P + R L +P YRE L SPASS SS S+ SD
Sbjct: 126 A------HEDDLQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDA 179
Query: 183 FS--------------------------PYTSPCVSPNNGGPDDLCPQFQNIPAHYSPRT 216
S P TSP SP ++ Q + SPR
Sbjct: 180 SSCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSLSPRQ 239
Query: 217 SPIMSPRTSLAEDSCLGRHSPVPRPASRSSSPGAKRRHSCAEALVA--LPPGASPQRSRS 274
SP SPR+S+ +++ L P P+SR +SP KRRHS AE A L P SP S
Sbjct: 240 SPCHSPRSSVTDENWLSPR-PASGPSSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPG 298
Query: 275 PSPQPSSHVAPQDHGSPAGYPPVAGSAVIMDALNSLATDSPCGIPPKMWKTSPDPSPVSA 334
SP+ S +D A V G + + A+ IP K KTS D + +
Sbjct: 299 HSPRGS---VTEDTWLNAS---VHGGSGLGPAVFPFQYCVETDIPLKTRKTSEDQAAI-- 350
Query: 335 APSKAGL----PRHIYPAVEFLGPCEQGE----RRNSAPESILLVPP--TWPKPLVPAIP 384
P K L + PA E G +++S + L VP TW KP P
Sbjct: 351 LPGKLELCSDDQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPSPFTWSKPKPGHTP 410
Query: 385 ICSIPVTASLPPLEWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVVQ 444
I T+SLPPL+WPL + G EL+IEVQPK HHRAHYETEGSRGAVKA TGGHPVV+
Sbjct: 411 IFR---TSSLPPLDWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVK 467
Query: 445 LHGYMENKPLGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPLE 504
L GY E KP+ LQ+FIGTAD+R L+PHAFYQVHRITGKTV T S E I+ +TKVLEIPL
Sbjct: 468 LLGYNE-KPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLL 526
Query: 505 PKNNMRATIDCAGILKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIVSLQTAS 564
P+NNM A+IDCAGILKLRN+DIELRKGETDIGRKNTRVRLVFRVHIP+ SG+++SLQ AS
Sbjct: 527 PENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIAS 586
Query: 565 NPIECSQRSAHELPMVERQDTDSCLVYGGQQMILTGQNFTSESKVVFTEKTTDGQQIWEM 624
P+ECSQRSA ELP +E+ +SC V GG +M++TG NF ESK++F EK DG+ WE+
Sbjct: 587 IPVECSQRSAQELPHIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEV 646
Query: 625 EATVDKDKSQPNMLFVEIPEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHPVPAIKTE 684
E + ++K Q + +E+P Y N + V+V+FY+ NGKRK+SQ Q FTY PV +K E
Sbjct: 647 EGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPV-LMKQE 705
Query: 685 PTDEYDPTLICSPTHGGLGSQPYYP-QHPMVAESPSCLVATMAPCQQFRTGLSSPDARYQ 743
+E D L S P P HP + PS +G S
Sbjct: 706 HREEID-----------LSSVPSLPVPHPAQTQRPSS-----------DSGCSHDSVLSG 743
Query: 744 QQNPAAVLYQRSKSLSPSLLGYQQPALMAAPLSLADAHR---SVLVHAGSQGQSSALLHP 800
Q++ + Q S+ S P L S++ S +VH Q + +
Sbjct: 744 QRSLICSIPQTYASMVTS---SHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTPPVGS 800
Query: 801 SPTNQQASPVIHYSPTNQQLRCGSHQEFQHIMYCENFA-PGTTRPGPPPVS 850
S Q + V++ PT + S QEF +++ ++ G G P+S
Sbjct: 801 SYQPMQTN-VVYNGPTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLS 850
>gi|27886559 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 3 isoform 4 [Homo sapiens]
Length = 1045
Score = 453 bits (1166), Expect = e-127
Identities = 346/891 (38%), Positives = 452/891 (50%), Gaps = 116/891 (13%)
Query: 26 DELDFSILFDYEYL--------NPNEEEPN------AHKVASPPSGPAYPDDVLDYGLKP 71
DELDF ++F + P + EP+ V PPS P + +GL
Sbjct: 10 DELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPLCLPHHGLPS 69
Query: 72 YSPLASLSGEPPGR--FGEPDRVGPQKF--LSAAKPAGASGLSPRIEITP----SHELIQ 123
+S + S S + + + K+ L KP P I+IT H+ +
Sbjct: 70 HSSVLSPSFQLQSHKNYEGTCEIPESKYSPLGGPKPFEC----PSIQITSISPNCHQELD 125
Query: 124 AVGPLRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGYREP-LCLSPASSGSSASFISDT 182
A + L + P + R L +P YRE L SPASS SS S+ SD
Sbjct: 126 A------HEDDLQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDA 179
Query: 183 FS--------------------------PYTSPCVSPNNGGPDDLCPQFQNIPAHYSPRT 216
S P TSP SP ++ Q + SPR
Sbjct: 180 SSCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSLSPRQ 239
Query: 217 SPIMSPRTSLAEDSCLGRHSPVPRPASRSSSPGAKRRHSCAEALVA--LPPGASPQRSRS 274
SP SPR+S+ +++ L P P+SR +SP KRRHS AE A L P SP S
Sbjct: 240 SPCHSPRSSVTDENWLSPR-PASGPSSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPG 298
Query: 275 PSPQPSSHVAPQDHGSPAGYPPVAGSAVIMDALNSLATDSPCGIPPKMWKTSPDPSPVSA 334
SP+ S +D A V G + + A+ IP K KTS D + +
Sbjct: 299 HSPRGS---VTEDTWLNAS---VHGGSGLGPAVFPFQYCVETDIPLKTRKTSEDQAAI-- 350
Query: 335 APSKAGL----PRHIYPAVEFLGPCEQGE----RRNSAPESILLVPP--TWPKPLVPAIP 384
P K L + PA E G +++S + L VP TW KP P
Sbjct: 351 LPGKLELCSDDQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPSPFTWSKPKPGHTP 410
Query: 385 ICSIPVTASLPPLEWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVVQ 444
I T+SLPPL+WPL + G EL+IEVQPK HHRAHYETEGSRGAVKA TGGHPVV+
Sbjct: 411 IFR---TSSLPPLDWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVK 467
Query: 445 LHGYMENKPLGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPLE 504
L GY E KP+ LQ+FIGTAD+R L+PHAFYQVHRITGKTV T S E I+ +TKVLEIPL
Sbjct: 468 LLGYNE-KPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLL 526
Query: 505 PKNNMRATIDCAGILKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIVSLQTAS 564
P+NNM A+IDCAGILKLRN+DIELRKGETDIGRKNTRVRLVFRVHIP+ SG+++SLQ AS
Sbjct: 527 PENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIAS 586
Query: 565 NPIECSQRSAHELPMVERQDTDSCLVYGGQQMILTGQNFTSESKVVFTEKTTDGQQIWEM 624
P+ECSQRSA ELP +E+ +SC V GG +M++TG NF ESK++F EK DG+ WE+
Sbjct: 587 IPVECSQRSAQELPHIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEV 646
Query: 625 EATVDKDKSQPNMLFVEIPEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHPVPAIKTE 684
E + ++K Q + +E+P Y N + V+V+FY+ NGKRK+SQ Q FTY PV +K E
Sbjct: 647 EGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPV-LMKQE 705
Query: 685 PTDEYDPTLICSPTHGGLGSQPYYP-QHPMVAESPSCLVATMAPCQQFRTGLSSPDARYQ 743
+E D L S P P HP + PS +G S
Sbjct: 706 HREEID-----------LSSVPSLPVPHPAQTQRPSS-----------DSGCSHDSVLSG 743
Query: 744 QQNPAAVLYQRSKSLSPSLLGYQQPALMAAPLSLADAHR---SVLVHAGSQGQSSALLHP 800
Q++ + Q S+ S P L S++ S +VH Q + +
Sbjct: 744 QRSLICSIPQTYASMVTS---SHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTPPVGS 800
Query: 801 SPTNQQASPVIHYSPTNQQLRCGSHQEFQHIMYCENFA-PGTTRPGPPPVS 850
S Q + V++ PT + S QEF +++ ++ G G P+S
Sbjct: 801 SYQPMQTN-VVYNGPTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLS 850
>gi|27886555 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 3 isoform 3 [Homo sapiens]
Length = 1065
Score = 453 bits (1166), Expect = e-127
Identities = 346/891 (38%), Positives = 452/891 (50%), Gaps = 116/891 (13%)
Query: 26 DELDFSILFDYEYL--------NPNEEEPN------AHKVASPPSGPAYPDDVLDYGLKP 71
DELDF ++F + P + EP+ V PPS P + +GL
Sbjct: 10 DELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPLCLPHHGLPS 69
Query: 72 YSPLASLSGEPPGR--FGEPDRVGPQKF--LSAAKPAGASGLSPRIEITP----SHELIQ 123
+S + S S + + + K+ L KP P I+IT H+ +
Sbjct: 70 HSSVLSPSFQLQSHKNYEGTCEIPESKYSPLGGPKPFEC----PSIQITSISPNCHQELD 125
Query: 124 AVGPLRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGYREP-LCLSPASSGSSASFISDT 182
A + L + P + R L +P YRE L SPASS SS S+ SD
Sbjct: 126 A------HEDDLQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDA 179
Query: 183 FS--------------------------PYTSPCVSPNNGGPDDLCPQFQNIPAHYSPRT 216
S P TSP SP ++ Q + SPR
Sbjct: 180 SSCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSLSPRQ 239
Query: 217 SPIMSPRTSLAEDSCLGRHSPVPRPASRSSSPGAKRRHSCAEALVA--LPPGASPQRSRS 274
SP SPR+S+ +++ L P P+SR +SP KRRHS AE A L P SP S
Sbjct: 240 SPCHSPRSSVTDENWLSPR-PASGPSSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPG 298
Query: 275 PSPQPSSHVAPQDHGSPAGYPPVAGSAVIMDALNSLATDSPCGIPPKMWKTSPDPSPVSA 334
SP+ S +D A V G + + A+ IP K KTS D + +
Sbjct: 299 HSPRGS---VTEDTWLNAS---VHGGSGLGPAVFPFQYCVETDIPLKTRKTSEDQAAI-- 350
Query: 335 APSKAGL----PRHIYPAVEFLGPCEQGE----RRNSAPESILLVPP--TWPKPLVPAIP 384
P K L + PA E G +++S + L VP TW KP P
Sbjct: 351 LPGKLELCSDDQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPSPFTWSKPKPGHTP 410
Query: 385 ICSIPVTASLPPLEWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVVQ 444
I T+SLPPL+WPL + G EL+IEVQPK HHRAHYETEGSRGAVKA TGGHPVV+
Sbjct: 411 IFR---TSSLPPLDWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVK 467
Query: 445 LHGYMENKPLGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPLE 504
L GY E KP+ LQ+FIGTAD+R L+PHAFYQVHRITGKTV T S E I+ +TKVLEIPL
Sbjct: 468 LLGYNE-KPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLL 526
Query: 505 PKNNMRATIDCAGILKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIVSLQTAS 564
P+NNM A+IDCAGILKLRN+DIELRKGETDIGRKNTRVRLVFRVHIP+ SG+++SLQ AS
Sbjct: 527 PENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIAS 586
Query: 565 NPIECSQRSAHELPMVERQDTDSCLVYGGQQMILTGQNFTSESKVVFTEKTTDGQQIWEM 624
P+ECSQRSA ELP +E+ +SC V GG +M++TG NF ESK++F EK DG+ WE+
Sbjct: 587 IPVECSQRSAQELPHIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEV 646
Query: 625 EATVDKDKSQPNMLFVEIPEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHPVPAIKTE 684
E + ++K Q + +E+P Y N + V+V+FY+ NGKRK+SQ Q FTY PV +K E
Sbjct: 647 EGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPV-LMKQE 705
Query: 685 PTDEYDPTLICSPTHGGLGSQPYYP-QHPMVAESPSCLVATMAPCQQFRTGLSSPDARYQ 743
+E D L S P P HP + PS +G S
Sbjct: 706 HREEID-----------LSSVPSLPVPHPAQTQRPSS-----------DSGCSHDSVLSG 743
Query: 744 QQNPAAVLYQRSKSLSPSLLGYQQPALMAAPLSLADAHR---SVLVHAGSQGQSSALLHP 800
Q++ + Q S+ S P L S++ S +VH Q + +
Sbjct: 744 QRSLICSIPQTYASMVTS---SHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTPPVGS 800
Query: 801 SPTNQQASPVIHYSPTNQQLRCGSHQEFQHIMYCENFA-PGTTRPGPPPVS 850
S Q + V++ PT + S QEF +++ ++ G G P+S
Sbjct: 801 SYQPMQTN-VVYNGPTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLS 850
>gi|4758804 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 3 isoform 2 [Homo sapiens]
Length = 1068
Score = 453 bits (1166), Expect = e-127
Identities = 346/891 (38%), Positives = 452/891 (50%), Gaps = 116/891 (13%)
Query: 26 DELDFSILFDYEYL--------NPNEEEPN------AHKVASPPSGPAYPDDVLDYGLKP 71
DELDF ++F + P + EP+ V PPS P + +GL
Sbjct: 10 DELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPLCLPHHGLPS 69
Query: 72 YSPLASLSGEPPGR--FGEPDRVGPQKF--LSAAKPAGASGLSPRIEITP----SHELIQ 123
+S + S S + + + K+ L KP P I+IT H+ +
Sbjct: 70 HSSVLSPSFQLQSHKNYEGTCEIPESKYSPLGGPKPFEC----PSIQITSISPNCHQELD 125
Query: 124 AVGPLRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGYREP-LCLSPASSGSSASFISDT 182
A + L + P + R L +P YRE L SPASS SS S+ SD
Sbjct: 126 A------HEDDLQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDA 179
Query: 183 FS--------------------------PYTSPCVSPNNGGPDDLCPQFQNIPAHYSPRT 216
S P TSP SP ++ Q + SPR
Sbjct: 180 SSCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSLSPRQ 239
Query: 217 SPIMSPRTSLAEDSCLGRHSPVPRPASRSSSPGAKRRHSCAEALVA--LPPGASPQRSRS 274
SP SPR+S+ +++ L P P+SR +SP KRRHS AE A L P SP S
Sbjct: 240 SPCHSPRSSVTDENWLSPR-PASGPSSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPG 298
Query: 275 PSPQPSSHVAPQDHGSPAGYPPVAGSAVIMDALNSLATDSPCGIPPKMWKTSPDPSPVSA 334
SP+ S +D A V G + + A+ IP K KTS D + +
Sbjct: 299 HSPRGS---VTEDTWLNAS---VHGGSGLGPAVFPFQYCVETDIPLKTRKTSEDQAAI-- 350
Query: 335 APSKAGL----PRHIYPAVEFLGPCEQGE----RRNSAPESILLVPP--TWPKPLVPAIP 384
P K L + PA E G +++S + L VP TW KP P
Sbjct: 351 LPGKLELCSDDQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPSPFTWSKPKPGHTP 410
Query: 385 ICSIPVTASLPPLEWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVVQ 444
I T+SLPPL+WPL + G EL+IEVQPK HHRAHYETEGSRGAVKA TGGHPVV+
Sbjct: 411 IFR---TSSLPPLDWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVK 467
Query: 445 LHGYMENKPLGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPLE 504
L GY E KP+ LQ+FIGTAD+R L+PHAFYQVHRITGKTV T S E I+ +TKVLEIPL
Sbjct: 468 LLGYNE-KPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLL 526
Query: 505 PKNNMRATIDCAGILKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIVSLQTAS 564
P+NNM A+IDCAGILKLRN+DIELRKGETDIGRKNTRVRLVFRVHIP+ SG+++SLQ AS
Sbjct: 527 PENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIAS 586
Query: 565 NPIECSQRSAHELPMVERQDTDSCLVYGGQQMILTGQNFTSESKVVFTEKTTDGQQIWEM 624
P+ECSQRSA ELP +E+ +SC V GG +M++TG NF ESK++F EK DG+ WE+
Sbjct: 587 IPVECSQRSAQELPHIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEV 646
Query: 625 EATVDKDKSQPNMLFVEIPEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHPVPAIKTE 684
E + ++K Q + +E+P Y N + V+V+FY+ NGKRK+SQ Q FTY PV +K E
Sbjct: 647 EGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPV-LMKQE 705
Query: 685 PTDEYDPTLICSPTHGGLGSQPYYP-QHPMVAESPSCLVATMAPCQQFRTGLSSPDARYQ 743
+E D L S P P HP + PS +G S
Sbjct: 706 HREEID-----------LSSVPSLPVPHPAQTQRPSS-----------DSGCSHDSVLSG 743
Query: 744 QQNPAAVLYQRSKSLSPSLLGYQQPALMAAPLSLADAHR---SVLVHAGSQGQSSALLHP 800
Q++ + Q S+ S P L S++ S +VH Q + +
Sbjct: 744 QRSLICSIPQTYASMVTS---SHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTPPVGS 800
Query: 801 SPTNQQASPVIHYSPTNQQLRCGSHQEFQHIMYCENFA-PGTTRPGPPPVS 850
S Q + V++ PT + S QEF +++ ++ G G P+S
Sbjct: 801 SYQPMQTN-VVYNGPTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLS 850
>gi|27886563 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 4 isoform 2 [Homo sapiens]
Length = 902
Score = 433 bits (1114), Expect = e-121
Identities = 363/969 (37%), Positives = 461/969 (47%), Gaps = 156/969 (16%)
Query: 26 DELDFSILFDYEYLNP------------NEEEPNAHKVA--SPPSGPAYPDDVLDYGLKP 71
+EL+F ++F E P +E+ P ++A PP A P + +P
Sbjct: 9 EELEFKLVFGEEKEAPPLGAGGLGEELDSEDAPPCCRLALGEPPPYGAAPIGIP----RP 64
Query: 72 YSPLASLSGEPPGRFGEPD--RVGPQKFLSAAKPAGASGLSP--RIEITPSHELIQAVGP 127
P + PP P P + + P G +G + R+ PS I ++ P
Sbjct: 65 PPPRPGMHSPPPRPAPSPGTWESQPARSVRLGGPGGGAGGAGGGRVLECPSIR-ITSISP 123
Query: 128 LRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGYREP--------LCLSPASSG-SSASF 178
A L E P A SPR P GF GYRE SP SS SS SF
Sbjct: 124 TPEPPAAL--EDNPDAWGDGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWSF 181
Query: 179 ISDTF--------------------------SPYTSPCVSPNNGGPDDLCPQFQNIPAHY 212
SD SP SP SP P+D + P
Sbjct: 182 FSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWTPEDPWSLYGPSPGGR 241
Query: 213 SPRTSPIMSPRTSLAEDSCLGRHSPVPRPAS-RSSSPGAKRRHSCAEALVALPPGASPQR 271
P EDS L +P P PAS R +SP KRR+S + P ASP
Sbjct: 242 GP-------------EDSWLLLSAPGPTPASPRPASPCGKRRYSSS----GTPSSASPAL 284
Query: 272 SRSPSPQPSSHVAPQDHGSPAGYPPVAGSAVIMDALNSLATDSPCGIPPKMWKTSPDPS- 330
SR S P P P GS D + + +S IP K +TS + +
Sbjct: 285 SRRGSLGEEGSEPPPPPPLPLARDP--GSPGPFDYVGAPPAES---IPQKTRRTSSEQAV 339
Query: 331 --PVSAAPSKAG--LPRHIYPAVEFLGPCEQGERRNSAPESILLVPP--TWPKPLVPA-I 383
P S P+ LP A E + P G R+ A L VP W K +
Sbjct: 340 ALPRSEEPASCNGKLP---LGAEESVAP-PGGSRKEVAGMDYLAVPSPLAWSKARIGGHS 395
Query: 384 PICSIPVTASLPPLEWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVV 443
PI T++LPPL+WPL SQ ELRIEVQP+ HHRAHYETEGSRGAVKA GGHPVV
Sbjct: 396 PIFR---TSALPPLDWPLPSQYEQLELRIEVQPRAHHRAHYETEGSRGAVKAAPGGHPVV 452
Query: 444 QLHGYMENKPLGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPL 503
+L GY E KPL LQ+FIGTADER L+PHAFYQVHRITGK V T SYE +V TKVLE+ L
Sbjct: 453 KLLGYSE-KPLTLQMFIGTADERNLRPHAFYQVHRITGKMVATASYEAVVSGTKVLEMTL 511
Query: 504 EPKNNMRATIDCAGILKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIVSLQTA 563
P+NNM A IDCAGILKLRN+DIELRKGETDIGRKNTRVRLVFRVH+P+ G++VS+Q A
Sbjct: 512 LPENNMAANIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQGGGKVVSVQAA 571
Query: 564 SNPIECSQRSAHELPMVERQDTDSCLVYGGQQMILTGQNFTSESKVVFTEKTTDGQQIWE 623
S PIECSQRSA ELP VE +C V GG++++LTG NF +SKVVF E+ DG+ WE
Sbjct: 572 SVPIECSQRSAQELPQVEAYSPSACSVRGGEELVLTGSNFLPDSKVVFIERGPDGKLQWE 631
Query: 624 MEATVDKDKSQPNMLFVEIPEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHPVPAIKT 683
EATV++ +S L + +PEY NK + PV+V FYV NG+RKRS Q F + PV K
Sbjct: 632 EEATVNRLQSNEVTLTLTVPEYSNKRVSRPVQVYFYVSNGRRKRSPTQSFRFLPV-ICKE 690
Query: 684 EPTDEYD----PTLICSPTHGGLGSQPYYPQHPMVA-ESPSCLVATMAPCQQFRTGLSSP 738
EP + P+ +P + P P +P E P+C ++ + F G+
Sbjct: 691 EPLPDSSLRGFPSASATPFGTDMDFSPPRPPYPSYPHEDPACETPYLS--EGFGYGM--- 745
Query: 739 DARYQQQNPAAVLYQRSKSLSPSLLG----YQQPALMAAPLSL-ADAHRSVLVHAGSQGQ 793
Y Q P Y+ + P G Q PA+ P +D + G +G
Sbjct: 746 PPLYPQTGPPP-SYRPGLRMFPETRGTTGCAQPPAVSFLPRPFPSDPY-------GGRGS 797
Query: 794 SSALLHP-SPTNQQASPVIHYSPTNQQLRCGSHQEFQHIMYCENFAPGTTRPGPPPVSQG 852
S +L P SP P + SP E P + P P
Sbjct: 798 SFSLGLPFSPPAPFRPPPLPASPP-----------------LEGPFPSQSDVHPLPAEGY 840
Query: 853 QRLSPGSYPTVIQQQNATSQRAAKNGPPVSDQKEVLPAGVTIKQEQNLDQTYLDDVNEII 912
++ PG P + A Q ++ G + V G+T L++V+EII
Sbjct: 841 NKVGPGYGP----GEGAPEQEKSRGGYSSGFRDSVPIQGIT-----------LEEVSEII 885
Query: 913 RKEFSGPPA 921
++ SG PA
Sbjct: 886 GRDLSGFPA 894
>gi|209862845 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 4 isoform 1 [Homo sapiens]
Length = 964
Score = 430 bits (1106), Expect = e-120
Identities = 324/781 (41%), Positives = 397/781 (50%), Gaps = 106/781 (13%)
Query: 8 PQPDGGDAPGHEPGGSPQDE-LDFSILFDYEYLNP------------NEEEPNAHKVA-- 52
P D G G S +DE L+F ++F E P +E+ P ++A
Sbjct: 53 PGRDLGAPAGSMGAASCEDEELEFKLVFGEEKEAPPLGAGGLGEELDSEDAPPCCRLALG 112
Query: 53 SPPSGPAYPDDVLDYGLKPYSPLASLSGEPPGRFGEPD--RVGPQKFLSAAKPAGASGLS 110
PP A P + +P P + PP P P + + P G +G +
Sbjct: 113 EPPPYGAAPIGIP----RPPPPRPGMHSPPPRPAPSPGTWESQPARSVRLGGPGGGAGGA 168
Query: 111 P--RIEITPSHELIQAVGPLRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGYREP---- 164
R+ PS I ++ P A L E P A SPR P GF GYRE
Sbjct: 169 GGGRVLECPSIR-ITSISPTPEPPAAL--EDNPDAWGDGSPRDYPPPEGFGGYREAGGQG 225
Query: 165 ----LCLSPASSG-SSASFISDTF--------------------------SPYTSPCVSP 193
SP SS SS SF SD SP SP SP
Sbjct: 226 GGAFFSPSPGSSSLSSWSFFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASP 285
Query: 194 NNGGPDDLCPQFQNIPAHYSPRTSPIMSPRTSLAEDSCLGRHSPVPRPAS-RSSSPGAKR 252
P+D + P P EDS L +P P PAS R +SP KR
Sbjct: 286 RPWTPEDPWSLYGPSPGGRGP-------------EDSWLLLSAPGPTPASPRPASPCGKR 332
Query: 253 RHSCAEALVALPPGASPQRSRSPSPQPSSHVAPQDHGSPAGYPPVAGSAVIMDALNSLAT 312
R+S + P ASP SR S P P P GS D + +
Sbjct: 333 RYSSS----GTPSSASPALSRRGSLGEEGSEPPPPPPLPLARDP--GSPGPFDYVGAPPA 386
Query: 313 DSPCGIPPKMWKTSPDPS---PVSAAPSKAG--LPRHIYPAVEFLGPCEQGERRNSAPES 367
+S IP K +TS + + P S P+ LP A E + P G R+ A
Sbjct: 387 ES---IPQKTRRTSSEQAVALPRSEEPASCNGKLP---LGAEESVAP-PGGSRKEVAGMD 439
Query: 368 ILLVPP--TWPKPLVPA-IPICSIPVTASLPPLEWPLSSQSGSYELRIEVQPKPHHRAHY 424
L VP W K + PI T++LPPL+WPL SQ ELRIEVQP+ HHRAHY
Sbjct: 440 YLAVPSPLAWSKARIGGHSPIFR---TSALPPLDWPLPSQYEQLELRIEVQPRAHHRAHY 496
Query: 425 ETEGSRGAVKAPTGGHPVVQLHGYMENKPLGLQIFIGTADERILKPHAFYQVHRITGKTV 484
ETEGSRGAVKA GGHPVV+L GY E KPL LQ+FIGTADER L+PHAFYQVHRITGK V
Sbjct: 497 ETEGSRGAVKAAPGGHPVVKLLGYSE-KPLTLQMFIGTADERNLRPHAFYQVHRITGKMV 555
Query: 485 TTTSYEKIVGNTKVLEIPLEPKNNMRATIDCAGILKLRNADIELRKGETDIGRKNTRVRL 544
T SYE +V TKVLE+ L P+NNM A IDCAGILKLRN+DIELRKGETDIGRKNTRVRL
Sbjct: 556 ATASYEAVVSGTKVLEMTLLPENNMAANIDCAGILKLRNSDIELRKGETDIGRKNTRVRL 615
Query: 545 VFRVHIPESSGRIVSLQTASNPIECSQRSAHELPMVERQDTDSCLVYGGQQMILTGQNFT 604
VFRVH+P+ G++VS+Q AS PIECSQRSA ELP VE +C V GG++++LTG NF
Sbjct: 616 VFRVHVPQGGGKVVSVQAASVPIECSQRSAQELPQVEAYSPSACSVRGGEELVLTGSNFL 675
Query: 605 SESKVVFTEKTTDGQQIWEMEATVDKDKSQPNMLFVEIPEYRNKHIRTPVKVNFYVINGK 664
+SKVVF E+ DG+ WE EATV++ +S L + +PEY NK + PV+V FYV NG+
Sbjct: 676 PDSKVVFIERGPDGKLQWEEEATVNRLQSNEVTLTLTVPEYSNKRVSRPVQVYFYVSNGR 735
Query: 665 RKRSQPQHFTYHPVPAIKTEPTDEYD----PTLICSPTHGGLGSQPYYPQHPMVA-ESPS 719
RKRS Q F + PV K EP + P+ +P + P P +P E P+
Sbjct: 736 RKRSPTQSFRFLPV-ICKEEPLPDSSLRGFPSASATPFGTDMDFSPPRPPYPSYPHEDPA 794
Query: 720 C 720
C
Sbjct: 795 C 795
>gi|27502388 nuclear factor of activated T-cells, cytosolic
component 1 isoform D [Homo sapiens]
Length = 353
Score = 387 bits (993), Expect = e-107
Identities = 208/352 (59%), Positives = 249/352 (70%), Gaps = 9/352 (2%)
Query: 456 LQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDC 515
LQ+FIGTAD+R+L+PHAFYQVHRITGKTV+TTS+E I+ NTKVLEIPL P+N+MRA IDC
Sbjct: 2 LQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDC 61
Query: 516 AGILKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIVSLQTASNPIECSQRSAH 575
AGILKLRN+DIELRKGETDIGRKNTRVRLVFRVH+P+ SGR +SLQ ASNPIECSQRSA
Sbjct: 62 AGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQ 121
Query: 576 ELPMVERQDTDSCLVYGGQQMILTGQNFTSESKVVFTEKTTDGQQIWEMEATVDKDKSQP 635
ELP+VE+Q TDS V GG++M+L+G NF +SKV+F EK DG +WEMEA D+D +P
Sbjct: 122 ELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKP 181
Query: 636 NMLFVEIPEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHP--VPAIKTEPTDEYDPTL 693
N L VEIP +RN+ I +PV V+FYV NGKRKRSQ Q FTY P VP IKTEPTD+Y+P
Sbjct: 182 NSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYEPAP 241
Query: 694 ICSPTHGGLG--SQPYYPQHPMVAESP-SCLVATMAPCQQFRTGL-SSPDARYQQQNPAA 749
C P GL +PYY Q + P SCLVA PC Q T + ++P + + +
Sbjct: 242 TCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSP 301
Query: 750 VLYQRS-KSLSPSLLGYQQPALMAAPLSLADAHRSVLVHAGSQGQSSALLHP 800
Y + S LG QPA A ++ D R V H GS GQ L P
Sbjct: 302 AAYTKGVASPGHCHLGLPQPAGEAP--AVQDVPRPVATHPGSPGQPPPALLP 351
>gi|27886520 nuclear factor of activated T-cells 5 isoform a [Homo
sapiens]
Length = 1455
Score = 221 bits (563), Expect = 2e-57
Identities = 123/284 (43%), Positives = 173/284 (60%), Gaps = 10/284 (3%)
Query: 398 EWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTG-GHPVVQLHGYMENKPLGL 456
++P+ S+ EL+I VQP+ HRA Y TEGSRG+VK T G P V+L G+ N+P+ L
Sbjct: 196 QYPVKSEGK--ELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGH--NEPVVL 251
Query: 457 QIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDCA 516
Q+F+G R+ KPH FYQ R+TG+ T I G T V+E+ L+P NNM +DC
Sbjct: 252 QVFVGNDSGRV-KPHGFYQACRVTGRNTTPCKEVDIEGTT-VIEVGLDPSNNMTLAVDCV 309
Query: 517 GILKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIVSLQTASNPIECSQRSAHE 576
GILKLRNAD+E R G +K+TR RLVFRV+I G ++LQT S+PI C+Q +
Sbjct: 310 GILKLRNADVEARIGIAGSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPAG-- 367
Query: 577 LPMVERQDTDSCLVYGGQQMILTGQNFTSESKVVFTEKTTDGQQIWEMEATVDKDKSQPN 636
+P + ++ SC V G +++ L G+NF +KV+F E +D + W+ EA +D + N
Sbjct: 368 VPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVSD-ENSWKSEAEIDMELFHQN 426
Query: 637 MLFVEIPEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHPVPA 680
L V++P Y ++HI PV V YV+ + Q FTY P PA
Sbjct: 427 HLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTPDPA 470
>gi|5729945 nuclear factor of activated T-cells 5 isoform c [Homo
sapiens]
Length = 1531
Score = 221 bits (563), Expect = 2e-57
Identities = 123/284 (43%), Positives = 173/284 (60%), Gaps = 10/284 (3%)
Query: 398 EWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTG-GHPVVQLHGYMENKPLGL 456
++P+ S+ EL+I VQP+ HRA Y TEGSRG+VK T G P V+L G+ N+P+ L
Sbjct: 272 QYPVKSEGK--ELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGH--NEPVVL 327
Query: 457 QIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDCA 516
Q+F+G R+ KPH FYQ R+TG+ T I G T V+E+ L+P NNM +DC
Sbjct: 328 QVFVGNDSGRV-KPHGFYQACRVTGRNTTPCKEVDIEGTT-VIEVGLDPSNNMTLAVDCV 385
Query: 517 GILKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIVSLQTASNPIECSQRSAHE 576
GILKLRNAD+E R G +K+TR RLVFRV+I G ++LQT S+PI C+Q +
Sbjct: 386 GILKLRNADVEARIGIAGSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPAG-- 443
Query: 577 LPMVERQDTDSCLVYGGQQMILTGQNFTSESKVVFTEKTTDGQQIWEMEATVDKDKSQPN 636
+P + ++ SC V G +++ L G+NF +KV+F E +D + W+ EA +D + N
Sbjct: 444 VPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVSD-ENSWKSEAEIDMELFHQN 502
Query: 637 MLFVEIPEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHPVPA 680
L V++P Y ++HI PV V YV+ + Q FTY P PA
Sbjct: 503 HLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTPDPA 546
>gi|164419746 nuclear factor of activated T-cells 5 isoform d [Homo
sapiens]
Length = 1548
Score = 221 bits (563), Expect = 2e-57
Identities = 123/284 (43%), Positives = 173/284 (60%), Gaps = 10/284 (3%)
Query: 398 EWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTG-GHPVVQLHGYMENKPLGL 456
++P+ S+ EL+I VQP+ HRA Y TEGSRG+VK T G P V+L G+ N+P+ L
Sbjct: 290 QYPVKSEGK--ELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGH--NEPVVL 345
Query: 457 QIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDCA 516
Q+F+G R+ KPH FYQ R+TG+ T I G T V+E+ L+P NNM +DC
Sbjct: 346 QVFVGNDSGRV-KPHGFYQACRVTGRNTTPCKEVDIEGTT-VIEVGLDPSNNMTLAVDCV 403
Query: 517 GILKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIVSLQTASNPIECSQRSAHE 576
GILKLRNAD+E R G +K+TR RLVFRV+I G ++LQT S+PI C+Q +
Sbjct: 404 GILKLRNADVEARIGIAGSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPAG-- 461
Query: 577 LPMVERQDTDSCLVYGGQQMILTGQNFTSESKVVFTEKTTDGQQIWEMEATVDKDKSQPN 636
+P + ++ SC V G +++ L G+NF +KV+F E +D + W+ EA +D + N
Sbjct: 462 VPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVSD-ENSWKSEAEIDMELFHQN 520
Query: 637 MLFVEIPEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHPVPA 680
L V++P Y ++HI PV V YV+ + Q FTY P PA
Sbjct: 521 HLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTPDPA 564
>gi|164419744 nuclear factor of activated T-cells 5 isoform b [Homo
sapiens]
Length = 1549
Score = 221 bits (563), Expect = 2e-57
Identities = 123/284 (43%), Positives = 173/284 (60%), Gaps = 10/284 (3%)
Query: 398 EWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTG-GHPVVQLHGYMENKPLGL 456
++P+ S+ EL+I VQP+ HRA Y TEGSRG+VK T G P V+L G+ N+P+ L
Sbjct: 290 QYPVKSEGK--ELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGH--NEPVVL 345
Query: 457 QIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDCA 516
Q+F+G R+ KPH FYQ R+TG+ T I G T V+E+ L+P NNM +DC
Sbjct: 346 QVFVGNDSGRV-KPHGFYQACRVTGRNTTPCKEVDIEGTT-VIEVGLDPSNNMTLAVDCV 403
Query: 517 GILKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIVSLQTASNPIECSQRSAHE 576
GILKLRNAD+E R G +K+TR RLVFRV+I G ++LQT S+PI C+Q +
Sbjct: 404 GILKLRNADVEARIGIAGSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPAG-- 461
Query: 577 LPMVERQDTDSCLVYGGQQMILTGQNFTSESKVVFTEKTTDGQQIWEMEATVDKDKSQPN 636
+P + ++ SC V G +++ L G+NF +KV+F E +D + W+ EA +D + N
Sbjct: 462 VPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVSD-ENSWKSEAEIDMELFHQN 520
Query: 637 MLFVEIPEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHPVPA 680
L V++P Y ++HI PV V YV+ + Q FTY P PA
Sbjct: 521 HLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTPDPA 564
>gi|27886524 nuclear factor of activated T-cells 5 isoform a [Homo
sapiens]
Length = 1455
Score = 221 bits (563), Expect = 2e-57
Identities = 123/284 (43%), Positives = 173/284 (60%), Gaps = 10/284 (3%)
Query: 398 EWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTG-GHPVVQLHGYMENKPLGL 456
++P+ S+ EL+I VQP+ HRA Y TEGSRG+VK T G P V+L G+ N+P+ L
Sbjct: 196 QYPVKSEGK--ELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGH--NEPVVL 251
Query: 457 QIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDCA 516
Q+F+G R+ KPH FYQ R+TG+ T I G T V+E+ L+P NNM +DC
Sbjct: 252 QVFVGNDSGRV-KPHGFYQACRVTGRNTTPCKEVDIEGTT-VIEVGLDPSNNMTLAVDCV 309
Query: 517 GILKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIVSLQTASNPIECSQRSAHE 576
GILKLRNAD+E R G +K+TR RLVFRV+I G ++LQT S+PI C+Q +
Sbjct: 310 GILKLRNADVEARIGIAGSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPAG-- 367
Query: 577 LPMVERQDTDSCLVYGGQQMILTGQNFTSESKVVFTEKTTDGQQIWEMEATVDKDKSQPN 636
+P + ++ SC V G +++ L G+NF +KV+F E +D + W+ EA +D + N
Sbjct: 368 VPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVSD-ENSWKSEAEIDMELFHQN 426
Query: 637 MLFVEIPEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHPVPA 680
L V++P Y ++HI PV V YV+ + Q FTY P PA
Sbjct: 427 HLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTPDPA 470
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 61.6 bits (148), Expect = 3e-09
Identities = 95/348 (27%), Positives = 123/348 (35%), Gaps = 57/348 (16%)
Query: 53 SPPSGPAYPDDVLDYGLKPYSPLASLSGEPPGRFG---EPDRVGPQKFLSAAKPAGASG- 108
SPP P D +P + + G+P G +P GP + AKP G +G
Sbjct: 373 SPPEPGDTPTD------EPDALYVACQGQPKGGHVTSMQPKEPGPLQ--CEAKPLGKAGV 424
Query: 109 -LSPRIEITPSHELI----QAVGPLRMRDAGLLVEQPPLAGVAASPRFTLP---VPGFEG 160
L P++E + E+ PL PP A + P LP +P
Sbjct: 425 QLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALH 484
Query: 161 YREPLCLSPASSGSSASFIS-----DTFSPYTSPCVSPNNGGPDDLCPQFQNIPAHYSPR 215
PL SP S S +S FSP +SP P P + P P
Sbjct: 485 LSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPS--PALET-PLSPPPE 541
Query: 216 TSPIMSPRTSLAEDSCLGRHSPVPRPASRSSSPGAKRRHSCAEALVALPPGASPQRSRSP 275
SP+ P E+S L SP P S P A R E PP P+ S
Sbjct: 542 ASPLSPP----FEESPL---SPPPEELPTSPPPEASRLSPPPEESPMSPP---PEESPMS 591
Query: 276 SPQPSSHVAPQDHGSPAGYPPVAGSAVIMDALNSLATDSPCGIPPKMWKTSPDP--SPVS 333
P +S + P SP PP +SP PP+ + SP P SP+S
Sbjct: 592 PPPEASRLFPPFEESPLSPPP---------------EESPLSPPPEASRLSPPPEDSPMS 636
Query: 334 AAPSKAGLPRHIYPAVEFLGPCEQGERRNSAPESILLVPPTWPKPLVP 381
P ++ P P V L P R + PE L PP P P
Sbjct: 637 PPPEES--PMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSP 682
Score = 56.6 bits (135), Expect = 1e-07
Identities = 100/391 (25%), Positives = 134/391 (34%), Gaps = 49/391 (12%)
Query: 19 EPGGSPQDELDFSILFDY------EYLNPNEEEPNAHKVASPPSGPA--YPDDVLDYGLK 70
EPG +P DE D + + +EP + + P G A + L+ L
Sbjct: 376 EPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLN 435
Query: 71 PYSPLASLSGEPPGRFGEPDRVGPQKFLSAAKPAGASGLSPRIEITPSHELIQAVGPLRM 130
PL E P P P + P AS LSP E P+ L +A+ R
Sbjct: 436 EEMPLLPPPEESP--LSPPPEESP-----TSPPPEASRLSPPPEELPASPLPEALHLSRP 488
Query: 131 RDAGLLVEQPPLAGVAASPRFTLPVPGFEGYREPLCLSPASSGSSASFISDTFSPYTSPC 190
+ L PP + P + P E PL S S A + P SP
Sbjct: 489 LEESPL-SPPPEESPLSPPPESSPFSPLE--ESPLSPPEESPPSPALETPLSPPPEASPL 545
Query: 191 VSPNNGGPDDLCPQFQNIPAHYSPRTSPIMSPRTSLAEDSCLGRHSPVPRPASRSSSPGA 250
P P L P + +P P S + P E+S + SP P + S P A
Sbjct: 546 SPPFEESP--LSPPPEELPTSPPPEASRLSPP----PEESPM---SPPPEESPMSPPPEA 596
Query: 251 KRRHSCAEALVALPPGASPQRSRSPSPQPSSHVAPQDHGSPAGYPPVAGSAVIMDALNSL 310
R E PP P+ S P +S ++P SP PP
Sbjct: 597 SRLFPPFEESPLSPP---PEESPLSPPPEASRLSPPPEDSPMSPPP-------------- 639
Query: 311 ATDSPCGIPPKMWKTSPDPSPVSAAPSKAGLPRHIYPAVEFLGPCEQGERRNSAPESILL 370
+SP PP++ + SP P +P P P P + R + PE
Sbjct: 640 -EESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPT 698
Query: 371 VPPTWPKPLVPAIPICSIPVTASLPPLEWPL 401
PP P P P S+ SLP E PL
Sbjct: 699 SPPPEDSPASPP-PEDSL---MSLPLEESPL 725
Score = 47.4 bits (111), Expect = 6e-05
Identities = 101/400 (25%), Positives = 129/400 (32%), Gaps = 91/400 (22%)
Query: 40 NPNEEEPNAHKVASPPSGPAYPDDVL---DYGLKPYSPLAS-LSGEPPGRFGEPDRVGPQ 95
+P+ PN V SP SG L D P +P AS + + PG P P
Sbjct: 2296 SPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPA 2355
Query: 96 KFLSAAKPAGASGLSPRIEITPSHELIQAVGPLRMRDAGLLVEQPPLAGVAASPRFTLPV 155
+ L+ + P+ P P A PL R + PP A P +LP
Sbjct: 2356 QALAPSPPSHPDIFRPGSYTDP-----YAQPPLTPRP-----QPPPPESCCALPPRSLP- 2404
Query: 156 PGFEGYREPLCLSPASSGSSASFISDTFSPYTSPCVSPNNGGPDDLCPQFQN-------- 207
+P PAS S +S + SP T +S P + P+FQ+
Sbjct: 2405 ------SDPFSRVPASPQSQSS----SQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPP 2454
Query: 208 ---------IPAHYSPRTSP--IMSPRTSLAEDSCLGRHSPVPRPASRSSSPGAKRRHSC 256
P H PR P + SLA S P PA + AK
Sbjct: 2455 SRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAK----- 2509
Query: 257 AEALVALPPGASPQRSRSP-------SPQPSSHVAPQDHGSPAGYPPVAGSAVIMDALNS 309
+P G P RSP +P P PQ G P+ PPV
Sbjct: 2510 ------VPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPV------------ 2551
Query: 310 LATDSPCGIPPKMWKTSPDPSPVSAAPSKAG---LPRHIYPAVEFLGPCEQGERRNSAPE 366
P PP + P P P + +P+ LGP S E
Sbjct: 2552 ---PQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSS-----GSTGE 2603
Query: 367 SILLVPPTWPKPLVPAIPICSIPVTASLPPLEWPLSSQSG 406
S L P P L P P SLP L S +SG
Sbjct: 2604 SYGLSPLRPPSVLPPPAP------DGSLPYLSHGASQRSG 2637
Score = 47.0 bits (110), Expect = 8e-05
Identities = 124/488 (25%), Positives = 165/488 (33%), Gaps = 113/488 (23%)
Query: 20 PGGSPQDELDFSILFDYEYLNPNEEEPNAHKVASPPSGPAYPDDVLDYGLKPYSPLASLS 79
P P +E S + +P EE P + SPPS PA L+ L P + LS
Sbjct: 493 PLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPS-PA-----LETPLSPPPEASPLS 546
Query: 80 GEPPGRFGEPDRVGPQKFLSAAKPAGASGLSPRIE------------ITPSHELIQAVGP 127
PP F E P + L + P AS LSP E ++P E + P
Sbjct: 547 --PP--FEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPP 602
Query: 128 LRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGYREPLCLSPASSGSSASFISD------ 181
E+ PL+ + R + P P P SP S S +S
Sbjct: 603 FEESPLSPPPEESPLSPPPEASRLS-PPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSR 661
Query: 182 -TFSPYTSPCVSPNNGGPDDLCPQFQNI--PAHYSPRTSPIM-SPRTSLAEDSCLG---R 234
+ P SP P P P+ + P SP + P SP + EDS +
Sbjct: 662 LSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLE 721
Query: 235 HSPV----------------------------PRPASRSSSPGAKRRHSCAE----ALVA 262
SP+ PRP SP A+ H + L A
Sbjct: 722 ESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCA 781
Query: 263 LP--PGASPQRSRSP--SPQPSS-HVAPQD---HGSPAGYPPVAGSAVIMDALNSLATDS 314
+P P SPQ + P SPQP H++PQ H SP P L S ++
Sbjct: 782 VPEEPHLSPQ-AEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHL-SPQSEE 839
Query: 315 PCGIP--------PKMWKTSPDPSPVSA------APSKAGLPRHIYPAVEFLGPC----- 355
PC P P++ K P P P+ LP P L P
Sbjct: 840 PCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPA 899
Query: 356 --EQGERRNSA-PESI-------------LLVPPTWPKPLVPAIPICSIPVTASLPPLEW 399
E GE S PE + L+ P P PL P I + P + L LE+
Sbjct: 900 LSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEY 959
Query: 400 PLSSQSGS 407
P ++ S
Sbjct: 960 PFGAKGDS 967
Score = 42.7 bits (99), Expect = 0.002
Identities = 109/433 (25%), Positives = 152/433 (35%), Gaps = 98/433 (22%)
Query: 41 PNEEEPNAHKVASPPSGPAYPDDVLDYGLKPYSPLASLSGEPPGRFGEPDRVGPQKFLSA 100
P E+ P + P+ P D ++ L+ SPL L EP P GP
Sbjct: 692 PPEDSPTSPPPEDSPASPPPEDSLMSLPLEE-SPLLPLPEEPQLC---PRSEGPHLSPRP 747
Query: 101 AKPAGASGLSPRIEITPSHELIQAVGPLRMRDAGLLVEQPPLAGVAASPRFTLPVPG--F 158
+P LSPR E H QA P E+P L V P + G
Sbjct: 748 EEPH----LSPRPE--EPHLSPQAEEPHLSPQP----EEPCLCAVPEEPHLSPQAEGPHL 797
Query: 159 EGYREPLCLSPASSGSSASFISDTFSPYTSPCVSPNNGGPDDLCPQFQNIPAHYSPRTS- 217
E L LSP T P+ SP P++ C Q +H SP++
Sbjct: 798 SPQPEELHLSP-----------QTEEPHLSPV-------PEEPCLSPQPEESHLSPQSEE 839
Query: 218 PIMSPRTSLAEDSCLGRHSPV-PRPASRSSSPGAKRRHSCAEALVALPPGASPQRSR--- 273
P +SPR + S P+ PRP PG + E L PP P S
Sbjct: 840 PCLSPRPEESHLSPELEKPPLSPRPEKPPEEPG---QCPAPEELPLFPPPGEPSLSPLLG 896
Query: 274 ---------------------SPSPQPS--SHVAPQDHGSP-------AGYPPVA----- 298
SPS +PS + P D P A PP
Sbjct: 897 EPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGE 956
Query: 299 -----GSAVIMDALNSLAT---DSPCGIPPKMWKTSPDPSPVSAAPSKAGLPRHIYPA-- 348
G+ D + LA ++P PP+ T P+P P P G P + PA
Sbjct: 957 LEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSP--VGPASP 1014
Query: 349 --VEFLGP-CEQGERRNSAPESILLVPPTWPKPLVPAIPICSIPVTASLPPLEWPLSSQS 405
+E L P C + + P++ PP+ P PA+P+ S+P S +S ++
Sbjct: 1015 ILMEPLPPQCSPLLQHSLVPQN---SPPSQCSP--PALPL-SVPSPLSPIGKVVGVSDEA 1068
Query: 406 GSYELRIEVQPKP 418
+E+ E +P
Sbjct: 1069 ELHEMETEKVSEP 1081
Score = 33.1 bits (74), Expect = 1.2
Identities = 80/359 (22%), Positives = 113/359 (31%), Gaps = 56/359 (15%)
Query: 41 PNEEEPNAHKVASPPSGPAYPDDVLDYGLKPYSPLASL----------SGEPPGRFGEPD 90
P + P + PP PA +GL P PL P G +P
Sbjct: 2151 PGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPP 2210
Query: 91 RVGPQKFLSAAKPAGASGLSPRIEITPSHELIQAVGPLRMRDAGL----LVEQPPLAGVA 146
+G A +P P TP H+ L+ R L + E P + G
Sbjct: 2211 MLGASSRPGAGQPGEFHTTPPG---TPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGK 2267
Query: 147 ASPRFTLPVPGFEGYREPLCLSPASSGSSASFISDTFSPYTSPCVSPNNGGPDDLCPQFQ 206
AS P P E + SS S+ SP + GG + P
Sbjct: 2268 ASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVF 2327
Query: 207 NIPAHYSPRTSPIMSPRTSLAEDSC--LGRHSPVPRPASRSSSPGAKRRHSCAEALVALP 264
P ++PR S E LG P P A+AL P
Sbjct: 2328 KAP----------LTPRASQVEPQSPGLGLRPQEPPP---------------AQALAPSP 2362
Query: 265 PGASPQRSRSPSPQPSSHVAP--QDHGSPAGYPPVAGSAVIMDALNSLATDSPCGIPPKM 322
P S +P S+ P Q +P PP S + SL +D +P
Sbjct: 2363 P------SHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPP-RSLPSDPFSRVPASP 2415
Query: 323 WKTSPDPSPVSAAP--SKAGLPRHIYPAVEFLGPCEQGERRNSAPESIL-LVPPTWPKP 378
S SP++ P ++A P + P + P + R + + L P P+P
Sbjct: 2416 QSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQP 2474
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 59.3 bits (142), Expect = 2e-08
Identities = 89/373 (23%), Positives = 128/373 (34%), Gaps = 49/373 (13%)
Query: 41 PNEEEPNAHKVASPPSGPAYPDDVLDYGLKPYSPLASLSGEPPGRFGEPDRVGPQKFLSA 100
P+ N SP P++ L + SP + S PP G P SA
Sbjct: 817 PDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTP-------SA 869
Query: 101 AKPAGASGLSPRIEITPSHELIQAVGPLRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEG 160
P G++ + TP+ ++ P + P L+ ++SP+ P +G
Sbjct: 870 VTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKG 929
Query: 161 YREPLCLSPASSGSSASFISDTFSPYTSPCVSPNN--GGPDDLCPQFQNIPAHYSPRTSP 218
+ SP+ G+ T P +P + GGP P++ P +P
Sbjct: 930 ----IPASPSPKGAP-----------TPPAATPPSPKGGPATPSPKWAPTPPAATP---- 970
Query: 219 IMSPRTSLAEDSCLGRHS-PVPRPASRSSSPGAKRRHSCAEALVALPPGASPQRSRSPSP 277
SP+ A S G + P P S P PP + +P P
Sbjct: 971 -PSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFP 1029
Query: 278 Q----PSSHVAPQDHGSPAGYP-----PVAGSAVIMDALNSLATDSPCGIPPKMWKTSPD 328
+ P + P GSPA P P +A + AT S G P T P
Sbjct: 1030 KGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPS 1089
Query: 329 PSPVSAAPSKAGLPRHIYPAVEFLGPCEQG----ERRNSAPESILLVPPTWPKPLVPAIP 384
P A PS G P + PA P +G AP + PP+ PK + P
Sbjct: 1090 PKGGPATPSPKGAP--MPPAA--TPPSPKGGLATPPHKGAPTTPAATPPS-PKGGLATPP 1144
Query: 385 ICSIPVT-ASLPP 396
P T A+ PP
Sbjct: 1145 PKGAPTTPAATPP 1157
Score = 53.9 bits (128), Expect = 7e-07
Identities = 94/372 (25%), Positives = 126/372 (33%), Gaps = 47/372 (12%)
Query: 46 PNAHKVASPPSGPAYPDDVLDYGLKPYSPLASLSGEPPGRFGEPDRVGPQKFLSAAKPAG 105
P A SP GPA P P P A+ PP G P P+ A P
Sbjct: 942 PPAATPPSPKGGPATPSPKW----APTPPAAT----PPSPKGGPATPSPK---GAPTPPA 990
Query: 106 ASGLSPRI-EITPSHE---LIQAVGPLRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGY 161
A+ SP+ TPS + AV P + + P G + P T P P
Sbjct: 991 ATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPK--GASTPPAATPPSP----- 1043
Query: 162 REPLCLSPASSGSSASFISDTFSPYTSPCVSPNNGGPDDLC---PQFQNIPAHYSPRTSP 218
+ +P G+ + + SP P G P P + PA SP+ +P
Sbjct: 1044 KGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAP 1103
Query: 219 IMSPRTSLAEDSCLGRHSPVPRPASRSSSPGAKRRHSCAEALVALPPGASPQRSRSPSPQ 278
+ T + L P + +++P + + L PP +P + P
Sbjct: 1104 MPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKG-----GLATPPPKGAPTTPAATPPS 1158
Query: 279 PSSHVA-PQDHGSP---AGYPPVAGSAVIMDALNSLATDSPCGIPPKMWKTSPDPSPVSA 334
P +A P G+P A PP LAT SP G P T P P A
Sbjct: 1159 PKGGLATPPPKGAPTTPAATPP--------SPKGGLATPSPKGAPTTPAATPPSPKGGLA 1210
Query: 335 APSKAGLPRHIYPAVEFLGPCEQGERRNSAPESILLVPPTWPKPLVPAIPICSIPVTASL 394
PS G P PA P +G +P+ P P P P P A
Sbjct: 1211 TPSPKGAP--TTPAA--TPPSPKGGLATPSPKGAPTTPAATP-PSPKGGPATPPPKGAPT 1265
Query: 395 PPLEWPLSSQSG 406
PP P S + G
Sbjct: 1266 PPAATPPSLKGG 1277
Score = 46.6 bits (109), Expect = 1e-04
Identities = 86/349 (24%), Positives = 123/349 (35%), Gaps = 50/349 (14%)
Query: 103 PAGASGLSPRI-EITPSHELIQAVGPLRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGY 161
P L+P I + PS L A P + + LA VA+SP+ P
Sbjct: 720 PLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPK-ECPT------ 772
Query: 162 REPLCLSPASSGSSASFISDTFSPY--------TSPCVSPNNGGPDDLCPQFQNIPAHYS 213
+ + ASS + ++++D+ SP P + GPD N+ + S
Sbjct: 773 EDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDT---PIGNLSSPVS 829
Query: 214 PRTSPIMSPRTSLA----EDSCLGRHSPVPRPASRSSSPGAKRRHSCAEALVALPPGASP 269
P + + P SL+ +DS HSP P + +P A S V LPP +P
Sbjct: 830 PVEASFL-PENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKG--VTLPPKETP 886
Query: 270 QRSRSPSPQPSSHVAPQDHGSPAGYPPVAGSAVIMDALNSLATDSPCGIPPKMWKTSPDP 329
S P P PA P A+ M + + PK + +P P
Sbjct: 887 TPSVVNLPFPKE--------GPATPAPKQAPALSMTSSS-----------PKKARATPAP 927
Query: 330 SPVSAAPSKAGLPRHIYPAVEFLGPCEQGERRNSAPESILLVPPTWPKPLVPAIPICSIP 389
+ A+PS G P PA P +G +P+ PP P P P
Sbjct: 928 KGIPASPSPKGAPTP--PAAT--PPSPKGGPATPSPKWAP-TPPAATPPSPKGGPATPSP 982
Query: 390 VTASLPPLEWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTG 438
A PP P S + G + P P +GS A P G
Sbjct: 983 KGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKG 1031
Score = 40.0 bits (92), Expect = 0.010
Identities = 48/199 (24%), Positives = 74/199 (37%), Gaps = 23/199 (11%)
Query: 198 PDDLCPQFQNIPAHYSPRTSPIMSPRTSLAEDSCLGRHSPVPRPASRSSSPGAKRRHSCA 257
P P Q P + + SP SP T + +P+ P +SSS A +
Sbjct: 46 PPPCSPAPQQCPLSAANQASPFPSPSTIAS--------TPLEVPFPQSSSGTALPLGTAP 97
Query: 258 EALVALPPGASPQRSRSPSPQPSSHVAPQDHGSPAGYPPVAGSAVIMDALNSLATDSPCG 317
EA LP P S + S +AP G+P+ P+A + AL +
Sbjct: 98 EAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLA-----LVALAPHSVQKSSA 152
Query: 318 IPPKMWKTSPDPSPVSAAPSKAGLPRHIYPAVEFLGPCEQGERRNSAPESILLVPPTWPK 377
PP + SP S A +++G + + P E N P ++ P P
Sbjct: 153 FPPNLL-----TSPPSVAVAESG---SVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPS 204
Query: 378 P--LVPAIPICSIPVTASL 394
P +V +P + AS+
Sbjct: 205 PPCIVSTVPYHCVTPMASI 223
Score = 40.0 bits (92), Expect = 0.010
Identities = 98/401 (24%), Positives = 122/401 (30%), Gaps = 67/401 (16%)
Query: 46 PNAHKVASPPSGPAYPDDV---LDYGLKPYSPLASLSGEPPGRFGEPDRVGPQ--KFLSA 100
P A SP GPA P P SP + P P V P K A
Sbjct: 965 PPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPA 1024
Query: 101 AKPAGASGLSPRIEITPSHELIQAVGPLRMRDAGLLVEQPPLAGVAASPRFTLP------ 154
A P +P PS + A PL G +P TLP
Sbjct: 1025 ATPFPKGASTPPAATPPSPKGSPAATPLPK-------------GAPTTPAATLPSPKGGP 1071
Query: 155 -VPGFEGYREPLCLSPASSGSSASFISDTFSPYTSPCVSPNNGGPDDLCPQFQNIPAHYS 213
P +G P +P S + S +P P +P + P + P +
Sbjct: 1072 ATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMP-PAATPPSPKGGLATPPHKGAPT--T 1128
Query: 214 PRTSPIMSPRTSLAEDSCLGRHSPV----PRPASRSSSPGAKRRHSCAEALVALPPGASP 269
P +P SP+ LA G + P P ++P K + A P G
Sbjct: 1129 PAATP-PSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLA 1187
Query: 270 QRSRSPSPQPSSHVAPQDHG-----SPAGYPPVAGSAVIMDALNSLATDSPCGIP----- 319
S +P + P G SP G P +A LAT SP G P
Sbjct: 1188 TPSPKGAPTTPAATPPSPKGGLATPSPKG-APTTPAATPPSPKGGLATPSPKGAPTTPAA 1246
Query: 320 -------------PKMWKTSPDPSPVS-----AAPSKAGLPRHIYPAVEFLGPCEQGERR 361
PK T P +P S A P G P PAV P +G
Sbjct: 1247 TPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPN---PAV-VTPPSPKGGPA 1302
Query: 362 NSAPESILLVPPTWPKPLVPAIPICSIPVTASLPPLEWPLS 402
S P+ PP P P P A PP P S
Sbjct: 1303 TSPPKG-APTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPS 1342
Score = 39.3 bits (90), Expect = 0.017
Identities = 97/406 (23%), Positives = 138/406 (33%), Gaps = 54/406 (13%)
Query: 8 PQPDGGDAPGHEPGGSPQDELDFSILFDYEYLNPNEEEPNAHKVASPPS---GPAYPDDV 64
P P GG A P G+P P+ + A+PPS GPA P
Sbjct: 1203 PSPKGGLATP-SPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPK 1261
Query: 65 LDYGLKPYSPLASLSGEPPGRFGEPDRVGPQK-FLSAAKPAGASGLSP-RIEITPSHELI 122
P P A+ G P + P ++ P G SP + TP
Sbjct: 1262 G----APTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPP---- 1313
Query: 123 QAVGPLRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGYREPLCLSPASSGSSASFISDT 182
A P G PP G P T P P +G +P+S G + S
Sbjct: 1314 AATPPSPKGSPGT----PPPKGAPTPPAVTPPSP--KGTPTLPATTPSSKGGPTT-PSSK 1366
Query: 183 FSPYTSPCVSPNN-GGPDDLCPQFQNIPAHYSPR---TSPIMSPRTSLAEDSCLGRHSPV 238
P T P +P++ GGP P + PA SP+ TSP + P + + +PV
Sbjct: 1367 EGP-TPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPA-----TPV 1420
Query: 239 PRPASRSSSPGAKRRHSCAEALVALPPGASPQRSRSPSPQPSSHVAPQDHGSPAGYPPVA 298
R + + S G + + P S +P P++ + D PA PP
Sbjct: 1421 TREGAATPSKGDLTPPAVTPVSLKKAPATS-----APKGGPATPSSKGDPTLPAVTPP-- 1473
Query: 299 GSAVIMDALNSLATDSPCGIPPKMWKTSPDPSPVSAAPSKAGLPRHIYPAVEFLGPCEQG 358
S A +AT S SP +P + AP A + P+ P
Sbjct: 1474 -SPKEPPAPKQVATSS-----------SPKKAPATPAPMGAPTLPAVIPSSPKEVPATPS 1521
Query: 359 ERRNSAPESILLVPPTWPKPLVP----AIPICSIPVTASLPPLEWP 400
RR+ + L+ P L P P ++P P + P
Sbjct: 1522 SRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTP 1567
Score = 35.0 bits (79), Expect = 0.32
Identities = 82/381 (21%), Positives = 134/381 (35%), Gaps = 56/381 (14%)
Query: 41 PNEEEPNAHKVASPPSGPAYPD---DVLDYGLKPYSPLAS----LSGEPPGRFGEPDRVG 93
P+ + A SP GPA P D + P SP + ++ E + D
Sbjct: 1376 PSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTP 1435
Query: 94 PQKFLSAAKPAGASGLSPRIEITPSHE---LIQAVGPLRMRDAGLLVEQPPLAGVAASPR 150
P + K A A+ TPS + + AV P ++ P ++SP+
Sbjct: 1436 PAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEP----PAPKQVATSSSPK 1491
Query: 151 FTLPVPGFEGYREPLCLSPASSGSSASFISDTFSPYTSPCVSPNNGGPDDLCPQFQNIPA 210
P G + P+S + S P + P L P+ IP
Sbjct: 1492 KAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPP 1551
Query: 211 HY---SPRTSP-IMSPRTSLAEDSCLGRHSP-VPRPASRSSSPGAKRRHSCAEALVALPP 265
SP+ +P I +P+ + A S SP P++ +P K L+ P
Sbjct: 1552 AMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKE-------LLIPPA 1604
Query: 266 GASPQRSRSPSPQ----PSSH---VAPQDHGSPAGYPPVAGSAV---------IMDALNS 309
SP +P+P PS P G+P PPV S++ + + +
Sbjct: 1605 VTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTS-PPVTPSSLKDSPTSPASVTCKMGA 1663
Query: 310 LATDSPCGIPPKMWKTS---------PDPSPVSAAPSKAGLPRHIYPAVEFLGPCEQGER 360
+ G+P K T+ P+ +P+ AP++ G P+ + C
Sbjct: 1664 TVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKG-PQTKKSSATSPPICPDPSA 1722
Query: 361 RNSAPESILLVPPTWPKPLVP 381
+N + + V P PL+P
Sbjct: 1723 KNGSKGPLSTVAPA---PLLP 1740
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 54.7 bits (130), Expect = 4e-07
Identities = 111/444 (25%), Positives = 153/444 (34%), Gaps = 59/444 (13%)
Query: 8 PQPDGGDAPGHEPGGSPQDELDFSILFDYEYLNPNEEEPNAHKVASPP---------SGP 58
P P GG G GGS + D + L+ K PP G
Sbjct: 453 PPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGL 512
Query: 59 AYPDDVLDYGLKPYSPLASLSGEPP---GRFGEPDRVGPQKFLSAAKPAGASGLSPRIEI 115
A PD L KP PP G G P ++ P + G S R
Sbjct: 513 AVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPR 572
Query: 116 TPSHELIQAVGPLRMRDAGLLVEQPP--LAGVAASPRFTLPVPGFEGYREPLCLSPASSG 173
+P L + G L PP LAG ASP P + R SP +S
Sbjct: 573 SPERTLSPSSGYSSQSGTPTL---PPKGLAGPPASPGKAQPP---KPERVTSLRSPGASV 626
Query: 174 SSASFISDTFSPYTSPCVSPNNG-------GPDDLCPQFQNIPAHYSPRTSPIMSPRTSL 226
SS+ ++ S + P S +G G + P +PA +SP P PR+
Sbjct: 627 SSS--LTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSP---PPSKPRSPN 681
Query: 227 AEDSCLGRHSPVPRPASRS-SSPGAKRRHSCAEALVALPPGASPQRSRSPSPQPSSHVAP 285
L + VP P S + +SP + + P S +S PSP PS H P
Sbjct: 682 PAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPP 741
Query: 286 QDHGSPAGYPPVAGSAVIMDALNSLAT-DSPCGIPPKMWKTSPDPSPVSAAPSKAGLPR- 343
PP V+++A ++ T + P P W P P+P S A P
Sbjct: 742 ---------PPTKKPEVVVEAPSASETAEEPLQDP--NWPPPPPPAPEEQDLSMADFPPP 790
Query: 344 ----HIYPAVEFLGPCEQGE------RRNSAPESILLVPP--TWPKPLVPA-IPICSIPV 390
+ E GP E +S+ ++ + PP P P PA P S P
Sbjct: 791 EEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPG 850
Query: 391 TASLPPLEWPLSSQSGSYELRIEV 414
+ P + P+ G R +V
Sbjct: 851 HVAKLPQKEPVGCSKGGGPPREDV 874
Score = 33.9 bits (76), Expect = 0.72
Identities = 74/305 (24%), Positives = 108/305 (35%), Gaps = 56/305 (18%)
Query: 53 SPPSGPAYPDDVLD-YGLKPYSPLASLSGEPPGRFGEPDRVGPQKFLSAAKPAGAS--GL 109
S SGP + D + + P+ + + PP + P+ P A P S
Sbjct: 643 SDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDA 702
Query: 110 SPRIEITPSHELIQAVGPLRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGYREPLCLSP 169
SP+ TP L PL+ + PP + P + P P ++P +
Sbjct: 703 SPQSPPTPQTTLT----PLQESPVISKDQSPP---PSPPPSYHPPPPPT---KKPEVVVE 752
Query: 170 ASSGSSASFISDTFSPYTSPCVSPNNGGPDDLCPQFQNIP-AHYSPRTSPIMSPRTSLAE 228
A S S + P PN P P+ Q++ A + P E
Sbjct: 753 APSASETA---------EEPLQDPNWPPPPPPAPEEQDLSMADFPP------------PE 791
Query: 229 DSCLGRHSPVPRPASRS----SSPGAKRRHSCAEALVALPPGASPQRSRSPSPQPSS--- 281
++ SP P S S SSP A S A AL PPG+ P+P P+S
Sbjct: 792 EAFFSVASPEPAGPSGSPELVSSPAASS--SSATALQIQPPGSPDPPPAPPAPAPASSAP 849
Query: 282 -HVAPQDHGSPAGY-----PP--VAGSAVIMDALNSLATDSPCGIPPKMWKTSPDPSPVS 333
HVA P G PP G+ ++ +L + G P +P P+
Sbjct: 850 GHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAP----GGAPTPALGP 905
Query: 334 AAPSK 338
+AP K
Sbjct: 906 SAPQK 910
>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
sapiens]
Length = 1636
Score = 53.9 bits (128), Expect = 7e-07
Identities = 101/457 (22%), Positives = 144/457 (31%), Gaps = 91/457 (19%)
Query: 39 LNPNEEEPNAHKVASPP-----------SGPAYPDDVLDYGLK---PYSPLASLSGEPPG 84
L P EE A + PP +GP PD L P SP S +G P
Sbjct: 726 LLPRREESEAVEAGDPPEELRSLPPDMVAGPRLPDTFLGSATPLHFPPSPFPSSTGPGPH 785
Query: 85 RFGEP----DRVGPQKFLSAAKPAGASGLSPRIEITPSHELIQAVGPLRMRDAGLLVEQP 140
P GP + + P + + + P L A P + GL+
Sbjct: 786 YLSGPLPPGTYSGPTQLIQPRAPGPHA-----MPVAPGPALYPA--PAYTPELGLVPRSS 838
Query: 141 PLAGVAASPRFTL-PVPGFEGYREPLCLSPASSGSSASFISDTFSPYTSPCVSPNNGGPD 199
P GV +SP + P P G P P SG P + V P D
Sbjct: 839 PQHGVVSSPYVGVGPAPPVAGL--PSAPPPQFSG-----------PELAMAVRPATTTVD 885
Query: 200 DLCPQFQNIPAHYSPRTSPIMSPRTSLAEDSCLGRHSPVPRPASRSSSPGAKRRHSCAEA 259
+ IP+H +PR +P +P C P P P + GAK+
Sbjct: 886 SIQAP---IPSHTAPRPNPTPAP-----PPPCFPVPPPQPLPTPYTYPAGAKQPIPAQHH 937
Query: 260 LVALPPGASPQRSRSPSPQPSSHVAPQDHGSPAGYPPVAGSAVIMDALNSLATDSPCGIP 319
+ P P P PQP PQ H S A P + + + +P +P
Sbjct: 938 FSSGIPAGFPAPRIGPQPQPH----PQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLP 993
Query: 320 PKMWKTSPDPSPVSAAPSKAGLPRHIYPAVEFLGPCEQGERRNSAPESILLVPPTWPKPL 379
P+ P P + P G P + GP + +S ++ P P+P
Sbjct: 994 PQ------SPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSG--ALPFPSPGPPQPP 1045
Query: 380 VPAIPICSIPVTASLPPLEWPLS----SQSGSYELRIEVQPKPHHRA------------- 422
P + P T + P PL+ S +G + P P
Sbjct: 1046 HPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPSPGPGPVPPRPPAAE 1105
Query: 423 ---------------HYETEGSRGAVKAPTGGHPVVQ 444
E G ++P GG P++Q
Sbjct: 1106 PPPCLRRGAAAADLLSSSPESQHGGTQSPGGGQPLLQ 1142
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 53.5 bits (127), Expect = 9e-07
Identities = 83/307 (27%), Positives = 105/307 (34%), Gaps = 55/307 (17%)
Query: 140 PPLAGVAASPRFTLPVPGFEGYREPLCLSPASSGSSASFISDTFSPYTSPCVSPNNGGPD 199
PPL G+ + P L P + L L P + S SP SP +P+ P+
Sbjct: 601 PPLQGLPSPPLSPLATPPPQA-PPXLALPPLQAPPSPPA-----SPPLSPLATPSPQAPN 654
Query: 200 DLC----------PQFQNIPAHYSPRTSPIMSPRT---SLAEDSCLGRHSPVPR--PASR 244
L P + A +SP SP +SP S A S VP PAS
Sbjct: 655 ALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP 714
Query: 245 SSSPGAKRRHSCAEALVA----LPPGASPQRSRSPSPQPSSHVAPQDHGSPAGYPPVAGS 300
SP A L A +PP SPS P V P P PP +
Sbjct: 715 PMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPA 774
Query: 301 AVIMDALNSLATDSPCGIPPKMWKTSPDPSPVSAAPSKAGLPRHIYPAVEFLGPCEQGER 360
++ M SP PP P P A P LP P F G
Sbjct: 775 SLPM---------SPLAKPP------PQAPPALATPPLQALPS---PPASFPGQAPFSPS 816
Query: 361 RNSAPESILLVPPTWPKPLVPAIPICSIPVTASL---------PPLEWPLSSQSGSYELR 411
S P S L PP P++ A P+ +P + PP P +S SG L
Sbjct: 817 A-SLPMSPLATPPPQAPPVL-AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGP-RLT 873
Query: 412 IEVQPKP 418
+ + P P
Sbjct: 874 LALAPGP 880
Score = 52.0 bits (123), Expect = 3e-06
Identities = 61/227 (26%), Positives = 89/227 (39%), Gaps = 29/227 (12%)
Query: 209 PAHYSPRTSPIMSPRTSLAEDSCLGRHSPVPRPASRSSSPGAKRRHSCAEALVALPPGAS 268
PA + P PR S++ S P P R S+ G +R + + P +S
Sbjct: 192 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS 251
Query: 269 PQRS----RSPSPQPSSHVAPQDHG-----SPAGYPPVAGSAVIMDALNS--LATDSPCG 317
P RS R P+ P+ G P PP +A + L+S LAT SP G
Sbjct: 252 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSG 311
Query: 318 IPPKMWKTSPDPSPVSAAPSKAGLPRHIYPAVEFLGPCEQGERRNSAPESILLVP----- 372
K P P P +AA LP + P+ P SAP S+ +P
Sbjct: 312 T-----KARPVPPPDNAATP---LPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPAT 363
Query: 373 -PTWPKPLVPAIPICSIPVTASLPPLEWPLSSQSGSYELRIEVQPKP 418
P+ P + P+ + P ++PP++ P S S S ++ P P
Sbjct: 364 PPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPS----LQAPPSP 406
Score = 48.5 bits (114), Expect = 3e-05
Identities = 99/397 (24%), Positives = 139/397 (35%), Gaps = 52/397 (13%)
Query: 41 PNEEEPNAHKVASP--PSGPAYPDDVLDYGLKPYSPLASLSGEPPGRFGEPDRVGPQKFL 98
P + + V+SP SG P + GL+ +S E G+ + L
Sbjct: 104 PPAKNTSPGPVSSPGRASGTTRPGPLGQKGLR-------ISAEETVARGKATEAPKRSAL 156
Query: 99 SAAKPAGASGLSPRIEITPSHELIQAVGPLRMRDAGLLVEQPPLAGVAA------SPRFT 152
SA SG +P TPS + + R R AG V P A A PR +
Sbjct: 157 SAGARRDTSGPTPG---TPSPAMAR-----RSRAAGTEVGLPRPAPSARPRPPTEGPRKS 208
Query: 153 LPVPGFEGYREPLCLS---PASSGSSASFISDTFSPYTSPCVSPNNGGPDDL-CPQFQNI 208
+ EP + P++ G S + S +P SP GP P+
Sbjct: 209 VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH 268
Query: 209 PAHYSP------RTSPIMSPRTSLAEDSCLGRHSPV--PRPASRSSSPGAKRRHSCAEAL 260
P+ P R + PR A SP+ P P+ + P ++
Sbjct: 269 PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLP 328
Query: 261 VALPPGAS-----PQRSRSPSPQPSSHVAPQDHGSPAGYPPVAGSAVIMDALNSLATDSP 315
LPP P SPS PS P +P P + + M A SL T P
Sbjct: 329 ATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPP 388
Query: 316 CGIPPKMWKTSPD----PSPVSAAPSKA----GLPRHIYPAVEFLGPC-EQGERRNSAPE 366
+P + TSP PSP++ + +A G P + FL Q + ++P
Sbjct: 389 IQVPHSL--TSPSLQAPPSPLALSSLQATTSLGSPT-LQATHSFLTMSPRQTQASLTSPS 445
Query: 367 SILLVPPTWPKPLVPAIPICSIPVTASLPPLEWPLSS 403
PP P P S P+ SL P PLSS
Sbjct: 446 RPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSS 482
Score = 46.6 bits (109), Expect = 1e-04
Identities = 88/354 (24%), Positives = 118/354 (33%), Gaps = 78/354 (22%)
Query: 70 KPYSPLASLSGEP---PGRFGEPDRVGPQK--FLSAAKPAGASGLSPRIEITPSHELIQA 124
+P S S S P P R G R P+ S KP G L P P + A
Sbjct: 236 RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA 295
Query: 125 VGPLRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGYREPLCLSPASSGSSASFISDTFS 184
+GPL PLA + S PVP + PL PA+ S +
Sbjct: 296 LGPL---------SSSPLATPSPSGTKARPVPPPDNAATPL---PATLPPSPPLATPL-- 341
Query: 185 PYTSPCVSPNNGGPDDLCPQFQNIPAHYSPRTSPIMSPRTSLAEDSCLGRHSPVPRPASR 244
P P+ P P Q +P+ P T P +P + P+ P S
Sbjct: 342 ----PLAPPSPSAP----PSLQTLPS--PPATPPSQAPPSMTTP--------PMQAPPSL 383
Query: 245 SSSPGAKRRHSCAEALVALPPGASPQRSRSPSPQP-SSHVAPQDHGSPAGYPPVAGSAVI 303
+ P + HS SP PSP SS A GSP
Sbjct: 384 QTIPPIQVPHSLT----------SPSLQAPPSPLALSSLQATTSLGSPT----------- 422
Query: 304 MDALNSLATDSP------CGIPPKMWKTSPDPSPVSAA---PSKAGLPRHIYPAVEFLGP 354
+ A +S T SP P + T PD P+ A P+ L + PAV L
Sbjct: 423 LQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSS 482
Query: 355 ----------CEQGERRNSAPESILLVPPTWPKPLVPAIPICSIPVTASLPPLE 398
AP S L++PP + + + + P + + PPLE
Sbjct: 483 PLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLE 536
Score = 46.6 bits (109), Expect = 1e-04
Identities = 102/422 (24%), Positives = 137/422 (32%), Gaps = 107/422 (25%)
Query: 41 PNEEEPNA---HKVASPPSGPAYPDDVLDYGLKPYSPLASLSGEPPGRFGEPDRVGPQKF 97
P+ + PNA H + +P S P P + P SP S S PP + P P
Sbjct: 648 PSPQAPNALAVHLLQAPFSPPPSPPVQAPFS-PPASPPVSPSATPPSQ-APPSLAAPPLQ 705
Query: 98 LSAAKPAGASGLSPRIEITPSHELIQAVGPLRMRDAGLLVEQPPLAGVAASPRFTLP--V 155
+ + PA +SP P A PL+ V P A SP T P V
Sbjct: 706 VPPSPPASPP-MSPSATPPPQAPPPLAAPPLQ-------VPPSPPASPPMSPSATPPPRV 757
Query: 156 PGFEGYREPLCLSPASSGSSASFISDTFSPYTSPCVSPNNGGPDDLCPQFQNIP------ 209
P PL +P + S SP P P P P Q +P
Sbjct: 758 P-------PLLAAPPLQVPPSPPASLPMSPLAKP---PPQAPPALATPPLQALPSPPASF 807
Query: 210 ---AHYSPRTSPIMSPRTS------------LAEDSCLGRHSPVPRPASRSSSPGAKRRH 254
A +SP S MSP + L + SP + R +PG
Sbjct: 808 PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSV 867
Query: 255 SCAEALVALPPGASPQRSRSPSPQPSSHVAPQDHGSPAGYPPVAGSAVIMDALNSLATDS 314
S +AL PG P SRSPS S P +AG +S AT +
Sbjct: 868 SGPRLTLALAPGPPPPPSRSPS-------------STLSGPDLAGH-------SSSATST 907
Query: 315 PCGIPPKMWKTSPDPSPVSAAPSKAGLPRHIYPAVEFLGPCEQGERRNSAPESILLVPPT 374
P + + + + P+ ++ P A L C P
Sbjct: 908 PEEL--RGYDSGPEGGAAASPPPDAE-----------LAACH---------------PAA 939
Query: 375 WPKPLVPAIPICSIPVTASLPPLEWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVK 434
W + P + P PL WP ++ GS + + YETEG A
Sbjct: 940 WSRGPAPPLAFRGAPGA----PLPWPPATGPGSADGLCTI---------YETEGPESATP 986
Query: 435 AP 436
AP
Sbjct: 987 AP 988
Score = 45.1 bits (105), Expect = 3e-04
Identities = 95/383 (24%), Positives = 136/383 (35%), Gaps = 54/383 (14%)
Query: 53 SPPSGPAYPDDVLDYGLK------PYSPLASLSGEPPGRFGEPDRVGPQKFLSAA-KPAG 105
+PPS P + + L P SPLA S + G P FL+ + +
Sbjct: 379 APPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQ 438
Query: 106 ASGLSP-RIEITPSHELIQAVGPLRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGYREP 164
AS SP R TP PL Q PL+ A+ P T P P
Sbjct: 439 ASLTSPSRPASTPPDS-----PPL----------QAPLSLPASPPLQTSLSPAVSPLSSP 483
Query: 165 LCLSPASSGSSASFISDTFSPYTS----PCVSPNNGGPDDL--------CPQFQNIPAHY 212
L + P + SS + S +P +S P + ++ P L P +N+P+
Sbjct: 484 LTIHPLQALSSLASHSPQ-APLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLA 542
Query: 213 SPRTSPIMSPRTS--LAEDSC------LGRHSPVPRPASRSSSPGAKRRHSCAEALVALP 264
P +P T+ L C SP+ P + S A AL + P
Sbjct: 543 PPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPP 602
Query: 265 PGASPQRSRSPSPQPSSHVAPQDHGSPAGYPPVAGSAVIMDALNSLATDSPCGIPPKMWK 324
P SP P P P PP ++ + L + + +P + + +
Sbjct: 603 LQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 662
Query: 325 T--SPDPSPVSAAPSKAGLPRHIYPAVEFLGPCEQGERRNSAPESILLVPPTWP--KPLV 380
SP PSP AP + P+ P Q +AP L VPP+ P P+
Sbjct: 663 APFSPPPSPPVQAPFSPPASPPVSPSAT---PPSQAPPSLAAPP--LQVPPSPPASPPMS 717
Query: 381 P-AIPICSIPVTASLPPLEWPLS 402
P A P P + PPL+ P S
Sbjct: 718 PSATPPPQAPPPLAAPPLQVPPS 740
Score = 42.4 bits (98), Expect = 0.002
Identities = 88/369 (23%), Positives = 132/369 (35%), Gaps = 61/369 (16%)
Query: 78 LSGEPPGRFGEPDRVGPQKFLSAAKPAGASGLSPRIEITPSHELIQAVGPLRMRDAGLLV 137
L+ PPG P V P +A + GA+G R P E +G + ++
Sbjct: 25 LTPRPPGSPRPPPPVTP----AALRVLGAAGAVGR---KPLAERAGGIGGATIPESAPRA 77
Query: 138 EQPPLAGVAASPRFTLPVPGFEGYREPLCLSPASSGSSASFISDTFSPYTSPCVSPNNGG 197
AG ++ + P G R P PA + S P +SP +
Sbjct: 78 GPTRSAGTSSRNPASRPPASGRGERAP----PAKNTSPG--------PVSSPGRASGTTR 125
Query: 198 PDDLCPQFQNIPAHYS-PRTSPIMSPRTSLAEDSCLGRHSPVPRPASRSSSPGAKRRHSC 256
P L + I A + R +P+ S G P + SP RR
Sbjct: 126 PGPLGQKGLRISAEETVARGKATEAPKRSALS---AGARRDTSGPTPGTPSPAMARRSRA 182
Query: 257 AEALVALPPGASPQRSRSPSPQPSSHV-APQDHGSPAGYP-----PVAGSAVIMDALNSL 310
A V LP A R R P+ P V + +H + P P AG + A SL
Sbjct: 183 AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 242
Query: 311 ATDSPCGIPPKMWKTSPDPSPVSAAPSKAGLPR-HIYPA------VEFLGPCE-QGERRN 362
++ + +P SP + PS G PR +P+ ++ L P + R++
Sbjct: 243 SSSA-----------TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKD 291
Query: 363 SAPE--SILLVPPTWPKPL------VPAIPICSIPVTASLPP-----LEWPLSSQSGSYE 409
+AP + P P P VP + P+ A+LPP PL+ S S
Sbjct: 292 AAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAP 351
Query: 410 LRIEVQPKP 418
++ P P
Sbjct: 352 PSLQTLPSP 360
>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
Length = 1612
Score = 53.1 bits (126), Expect = 1e-06
Identities = 87/375 (23%), Positives = 135/375 (36%), Gaps = 52/375 (13%)
Query: 164 PLCLSPASSGSSASFISDTFSPYTSPCVSPN-NGGPDDLCPQFQNIPAHYSPRTSPIMSP 222
P L P+SS + S + SP TSPC SP + GP P P +P +P
Sbjct: 1066 PQHLQPSSSSGLGT--SPSSSPRTSPCQSPTISEGPVPSLP--------IRPSRAPSRTP 1115
Query: 223 RTSLAEDSCLGRHSPVPRPASRSSSPGAKRRHSCAEALVALPPGASPQRSRSPSPQPSSH 282
A+ S + P P + P +R + A PQR PS S
Sbjct: 1116 GPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPA 1175
Query: 283 VAPQDHGSPAGYPPVAGSA-VIMDALNSLATDSPCGI-----PPKMWKTSPDPSPVSAA- 335
++ G G PP G A M+A S T I P+ P P+ S A
Sbjct: 1176 PTRKEFGG-IGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTAR 1234
Query: 336 ---PSKAGL----PRHIYPAVEFLGPCEQGERRNSAPESILLVPPTWPKPLVPAIPICSI 388
P +AG+ H + L P Q + ++ S L P P+ P P S+
Sbjct: 1235 PTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFP--PQSSL 1292
Query: 389 PVTAS-----LPPLEWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVV 443
P A L P+ P+ L QP P R+ + ++ + P V
Sbjct: 1293 PPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSH-------SLPSEASSQPQV 1345
Query: 444 QLHGYMENK---PLGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLE 500
+ +G + K PL + F + + A V TS ++++
Sbjct: 1346 KTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQ---------TSPVPTPDPKRLIQ 1396
Query: 501 IPLEPKNNMRATIDC 515
+P ++N+ +++ C
Sbjct: 1397 LPSATQSNVLSSVSC 1411
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 51.6 bits (122), Expect = 3e-06
Identities = 98/401 (24%), Positives = 131/401 (32%), Gaps = 109/401 (27%)
Query: 41 PNEEEPNA---HKVASPPSGPAYPDDVLDYGLKPYSPLASLSGEPPGRFGEPDRVGPQKF 97
P+ + PNA H + +P S P P + P SP S S PP + P P
Sbjct: 423 PSPQAPNALAVHLLQAPFSPPPSPPVQAPFS-PPASPPVSPSATPPSQ-APPSLAAPPLQ 480
Query: 98 LSAAKPAGASGLSPRIEITPSHELIQAVGPLRMRDAGLLVEQPPLA--GVAASPRFTLPV 155
+ + PA +SP P A PL+ L + PP A +A P LP
Sbjct: 481 VPPSPPASPP-MSPSATPPPQAPPPLAAPPLQ------LAKPPPQAPPALATPPLQALPS 533
Query: 156 PGFEGYREPLCLSPASSGSSASFISDTFSPYTSPCVSPNNGGPDDLCPQFQNIPAHYSPR 215
P PAS A F P SP +P P L +P SP
Sbjct: 534 P------------PASFPGQAPFSPSASLPM-SPLATPPPQAPPVLAAPLLQVPP--SPP 578
Query: 216 TSPIMSPRTSLAEDSCLGRHSPVPRPASRSSSPGAKRRHSCAEALVALPPGASPQRSRSP 275
SP + R P P P + S P +AL PG P SRSP
Sbjct: 579 ASPTLQAP----------RRPPTPGPDTSVSGP---------RLTLALAPGPPPPPSRSP 619
Query: 276 SPQPSSHVAPQDHGSPAGYPPVAGSAVIMDALNSLATDSPCGIPPKMWKTSPDPSPVSAA 335
S S P +AG +S AT +P + + + + P+ ++
Sbjct: 620 S-------------STLSGPDLAGH-------SSSATSTPEEL--RGYDSGPEGGAAASP 657
Query: 336 PSKAGLPRHIYPAVEFLGPCEQGERRNSAPESILLVPPTWPKPLVPAIPICSIPVTASLP 395
P A L C P W + P + P
Sbjct: 658 PPDAE-----------LAACH---------------PAAWSRGPAPPLAFRGAPGA---- 687
Query: 396 PLEWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAP 436
PL WP ++ GS + + YETEG A AP
Sbjct: 688 PLPWPPATGPGSADGLCTI---------YETEGPESATPAP 719
Score = 44.7 bits (104), Expect = 4e-04
Identities = 86/344 (25%), Positives = 113/344 (32%), Gaps = 72/344 (20%)
Query: 70 KPYSPLASLSGEP---PGRFGEPDRVGPQK--FLSAAKPAGASGLSPRIEITPSHELIQA 124
+P S S S P P R G R P+ S KP G L P P + A
Sbjct: 236 RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA 295
Query: 125 VGPLRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGYREPLCLSPASSGSSASFISDTFS 184
+GPL + L P A + + TLP +P SS + +
Sbjct: 296 LGPL---SSSPLATPSPSAALQSQAPPTLPA------------TPHSSSLTCQLATPL-- 338
Query: 185 PYTSPCVSPNNGGPDDLCPQFQNIPAHYSPRTSPIMSPRTSLAEDSCLGRHSPVPRPASR 244
P P+ P P Q +P SP +P TSL
Sbjct: 339 ----PLAPPSPSAP----PSLQTLP---SPPATPPSQATTSLG----------------- 370
Query: 245 SSSPGAKRRHSCAEA-----LVALPPGASPQRSRSPSPQPSSHVAPQDHGSPAGYPPVAG 299
SP + HS + L PP A P + P P S A A P A
Sbjct: 371 --SPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAP 428
Query: 300 SAVIMDALNSLATDSPCGIPPKMWKTSPDPSP---VSAAPSKAGLPRHIYPAVEFLGPCE 356
+A+ + L A SP PP SP SP SA P P P ++
Sbjct: 429 NALAVHLLQ--APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV----- 481
Query: 357 QGERRNSAPESILLVPPTWPKPLVPAIPICSIPVTASLPPLEWP 400
S P S + P P P P P+ + P+ + PP + P
Sbjct: 482 ----PPSPPASPPMSPSATPPPQAPP-PLAAPPLQLAKPPPQAP 520
Score = 42.7 bits (99), Expect = 0.002
Identities = 92/397 (23%), Positives = 137/397 (34%), Gaps = 55/397 (13%)
Query: 78 LSGEPPGRFGEPDRVGPQKFLSAAKPAGASGLSPRIEITPSHELIQAVGPLRMRDAGLLV 137
L+ PPG P V P +A + GA+G R P E +G + ++
Sbjct: 25 LTPRPPGSPRPPPPVTP----AALRVLGAAGAVGR---KPLAERAGGIGGATIPESAPRA 77
Query: 138 EQPPLAGVAASPRFTLPVPGFEGYREPLCLSPASSGSSASFISDTFSPYTSPCVSPNNGG 197
AG ++ + P G R P PA + S P +SP +
Sbjct: 78 GPTRSAGTSSRNPASRPPASGRGERAP----PAKNTSPG--------PVSSPGRASGTTR 125
Query: 198 PDDLCPQFQNIPAHYS-PRTSPIMSPRTSLAEDSCLGRHSPVPRPASRSSSPGAKRRHSC 256
P L + I A + R +P+ S G P + SP RR
Sbjct: 126 PGPLGQKGLRISAEETVARGKATEAPKRSALS---AGARRDTSGPTPGTPSPAMARRSRA 182
Query: 257 AEALVALPPGASPQRSRSPSPQPSSHV-APQDHGSPAGYP-----PVAGSAVIMDALNSL 310
A V LP A R R P+ P V + +H + P P AG + A SL
Sbjct: 183 AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 242
Query: 311 ATD-SPCGIPPKMWKTSPDPSPVSAAPS-------KAGLPRHIYP----AVEFLGPCEQG 358
++ +P P + ++ A PS +A P + P A LGP
Sbjct: 243 SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 302
Query: 359 ERRNSAPESILLVPPTWPKPLVPAIPICSIPVTASLPPLEWPLSSQSGSYELRIEVQPKP 418
+P + L + P +PA P S PL PL+ S S ++ P P
Sbjct: 303 PLATPSPSAAL---QSQAPPTLPATPHSSSLTCQLATPL--PLAPPSPSAPPSLQTLPSP 357
Query: 419 HHRAHYETEGSRGAVKAPTGGHPVVQ-LHGYMENKPL 454
+ S G+ P +Q H ++ + PL
Sbjct: 358 PATPPSQATTSLGS--------PTLQATHSFLPSPPL 386
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 51.6 bits (122), Expect = 3e-06
Identities = 98/401 (24%), Positives = 131/401 (32%), Gaps = 109/401 (27%)
Query: 41 PNEEEPNA---HKVASPPSGPAYPDDVLDYGLKPYSPLASLSGEPPGRFGEPDRVGPQKF 97
P+ + PNA H + +P S P P + P SP S S PP + P P
Sbjct: 384 PSPQAPNALAVHLLQAPFSPPPSPPVQAPFS-PPASPPVSPSATPPSQ-APPSLAAPPLQ 441
Query: 98 LSAAKPAGASGLSPRIEITPSHELIQAVGPLRMRDAGLLVEQPPLA--GVAASPRFTLPV 155
+ + PA +SP P A PL+ L + PP A +A P LP
Sbjct: 442 VPPSPPASPP-MSPSATPPPQAPPPLAAPPLQ------LAKPPPQAPPALATPPLQALPS 494
Query: 156 PGFEGYREPLCLSPASSGSSASFISDTFSPYTSPCVSPNNGGPDDLCPQFQNIPAHYSPR 215
P PAS A F P SP +P P L +P SP
Sbjct: 495 P------------PASFPGQAPFSPSASLPM-SPLATPPPQAPPVLAAPLLQVPP--SPP 539
Query: 216 TSPIMSPRTSLAEDSCLGRHSPVPRPASRSSSPGAKRRHSCAEALVALPPGASPQRSRSP 275
SP + R P P P + S P +AL PG P SRSP
Sbjct: 540 ASPTLQAP----------RRPPTPGPDTSVSGP---------RLTLALAPGPPPPPSRSP 580
Query: 276 SPQPSSHVAPQDHGSPAGYPPVAGSAVIMDALNSLATDSPCGIPPKMWKTSPDPSPVSAA 335
S S P +AG +S AT +P + + + + P+ ++
Sbjct: 581 S-------------STLSGPDLAGH-------SSSATSTPEEL--RGYDSGPEGGAAASP 618
Query: 336 PSKAGLPRHIYPAVEFLGPCEQGERRNSAPESILLVPPTWPKPLVPAIPICSIPVTASLP 395
P A L C P W + P + P
Sbjct: 619 PPDAE-----------LAACH---------------PAAWSRGPAPPLAFRGAPGA---- 648
Query: 396 PLEWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAP 436
PL WP ++ GS + + YETEG A AP
Sbjct: 649 PLPWPPATGPGSADGLCTI---------YETEGPESATPAP 680
Score = 43.5 bits (101), Expect = 0.001
Identities = 82/335 (24%), Positives = 115/335 (34%), Gaps = 55/335 (16%)
Query: 83 PGRFGEPDRVGPQKFLSAAKPAGASGLSPRIEITPSHEL-IQAVGPLRMRDAGLLVEQPP 141
P P GP+K +S+A + SP PS +Q + + + P
Sbjct: 185 PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 244
Query: 142 LAGVAA--SPRF----TLPVP-GFEGYREPLCLSPASSGSSA-SFISDTFSPYTSPCVSP 193
+G +A +PR + P P G + R P P + A +S + SP P
Sbjct: 245 RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPP 304
Query: 194 NNGGPDDLCPQFQNIPAHYSPRTSPIMSPRTSLAEDSCLGRHSPVPRPASRSSSPGAKRR 253
+ P P Q +P SP +P TSL SP +
Sbjct: 305 SPSAP----PSLQTLP---SPPATPPSQATTSLG-------------------SPTLQAT 338
Query: 254 HSCAEA-----LVALPPGASPQRSRSPSPQPSSHVAPQDHGSPAGYPPVAGSAVIMDALN 308
HS + L PP A P + P P S A A P A +A+ + L
Sbjct: 339 HSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 398
Query: 309 SLATDSPCGIPPKMWKTSPDPSP---VSAAPSKAGLPRHIYPAVEFLGPCEQGERRNSAP 365
A SP PP SP SP SA P P P ++ S P
Sbjct: 399 --APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV---------PPSPP 447
Query: 366 ESILLVPPTWPKPLVPAIPICSIPVTASLPPLEWP 400
S + P P P P P+ + P+ + PP + P
Sbjct: 448 ASPPMSPSATPPPQAPP-PLAAPPLQLAKPPPQAP 481
Score = 42.0 bits (97), Expect = 0.003
Identities = 88/363 (24%), Positives = 130/363 (35%), Gaps = 64/363 (17%)
Query: 78 LSGEPPGRFGEPDRVGPQKFLSAAKPAGASGLSPRIEITPSHELIQAVGPLRMRDAGLLV 137
L+ PPG P V P +A + GA+G R P E +G +
Sbjct: 25 LTPRPPGSPRPPPPVTP----AALRVLGAAGAVGR---KPLAERAGGIG------GATIP 71
Query: 138 EQPPLAGVAASPRFTLPVPGFEGYREPLCLSPASSGSSASFISDTFSPYTSPCVSPNNGG 197
E P AG + R P G R P PA + S P +SP +
Sbjct: 72 ESAPRAGPTRTSR---PPASGRGERAP----PAKNTSPG--------PVSSPGRASGTTR 116
Query: 198 PDDLCPQFQNIPAHYS-PRTSPIMSPRTSLAEDSCLGRHSPVPRPASRSSSPGAKRRHSC 256
P L + I A + R +P+ S G P + SP RR
Sbjct: 117 PGPLGQKGLRISAEETVARGKATEAPKRSALS---AGARRDTSGPTPGTPSPAMARRSRA 173
Query: 257 AEALVALPPGASPQRSRSPSPQPSSHV-APQDHGSPAGYP-----PVAGSAVIMDALNSL 310
A V LP A R R P+ P V + +H + P P AG + A SL
Sbjct: 174 AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 233
Query: 311 ATDSPCGIPPKMWKTSPDPSPVSAAPSKAGLPR-HIYPA------VEFLGPCE-QGERRN 362
++ + +P SP + PS G PR +P+ ++ L P + R++
Sbjct: 234 SSSA-----------TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKD 282
Query: 363 SAP-----ESILLVPPTWPKPLVPAIP--ICSIPVTASLPPLEWPLSSQSGSYELRIEVQ 415
+AP S L P+ P P+ P + ++P + PP + S S + +
Sbjct: 283 AAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFL 342
Query: 416 PKP 418
P P
Sbjct: 343 PSP 345
>gi|237757308 synaptojanin 1 isoform b [Homo sapiens]
Length = 1350
Score = 51.2 bits (121), Expect = 4e-06
Identities = 73/281 (25%), Positives = 101/281 (35%), Gaps = 33/281 (11%)
Query: 164 PLCLSPASSGSSASFISDTFSPYTSPCVSPN-NGGPDDLCPQFQNIPAHYSPRTSPIMSP 222
P L P+SS + S + SP TSPC SP + GP P P +P +P
Sbjct: 1066 PQHLQPSSSSGLGT--SPSSSPRTSPCQSPTISEGPVPSLP--------IRPSRAPSRTP 1115
Query: 223 RTSLAEDSCLGRHSPVPRPASRSSSPGAKRRHSCAEALVALPPGASPQRSRSPSPQPSSH 282
A+ S + P P + P +R + A PQR PS S
Sbjct: 1116 GPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPA 1175
Query: 283 VAPQDHGSPAGYPPVAGSA-VIMDALNSLATDSPCGI-----PPKMWKTSPDPSPVSAA- 335
++ G G PP G A M+A S T I P+ P P+ S A
Sbjct: 1176 PTRKEFGG-IGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTAR 1234
Query: 336 ---PSKAGL----PRHIYPAVEFLGPCEQGERRNSAPESILLVPPTWPKPLVPAIPICSI 388
P +AG+ H + L P Q + ++ S L P P+ P P S+
Sbjct: 1235 PTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFP--PQSSL 1292
Query: 389 PVTAS-----LPPLEWPLSSQSGSYELRIEVQPKPHHRAHY 424
P A L P+ P+ L QP P R+ +
Sbjct: 1293 PPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSH 1333
>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
Length = 1526
Score = 50.8 bits (120), Expect = 6e-06
Identities = 75/343 (21%), Positives = 115/343 (33%), Gaps = 48/343 (13%)
Query: 196 GGPDDLCPQFQNI-PAHYSPR------TSPIMSPRTSLAEDSCLGRHSPVP--------R 240
G DD + + + P H P TSP SPRTS + + PVP
Sbjct: 1008 GDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTIS-EGPVPSLPIRPSRA 1066
Query: 241 PASRSSSPGAKRRHSCAEALVALPPGASPQRSRSPSPQPSSHVAPQDHGSPAGYPPVAGS 300
P+ P A+ A+ LP Q P P VAP +P PP
Sbjct: 1067 PSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSG 1126
Query: 301 AVIMDALNSLATDSPCGIPPKMWKTSPDPSPVSAAPSKAGLPRHIYPAVEFLGPCEQGER 360
LA P G P +SA S H + L P Q +
Sbjct: 1127 RSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQS------HARASAGRLTPESQSKT 1180
Query: 361 RNSAPESILLVPPTWPKPLVPAIPICSIPVTAS-----LPPLEWPLSSQSGSYELRIEVQ 415
++ S L P P+ P P S+P A L P+ P+ L Q
Sbjct: 1181 SETSKGSTFLPEPLKPQAAFP--PQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQ 1238
Query: 416 PKPHHRAHYETEGSRGAVKAPTGGHPVVQLHGYMENK---PLGLQIFIGTADERILKPHA 472
P P R+ + ++ + P V+ +G + K PL + F + + A
Sbjct: 1239 PPPRSRSSH-------SLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKA 1291
Query: 473 FYQVHRITGKTVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDC 515
V TS +++++P ++N+ +++ C
Sbjct: 1292 QLSVQ---------TSPVPTPDPKRLIQLPSATQSNVLSSVSC 1325
Score = 49.7 bits (117), Expect = 1e-05
Identities = 76/275 (27%), Positives = 103/275 (37%), Gaps = 41/275 (14%)
Query: 164 PLCLSPASSGSSASFISDTFSPYTSPCVSPN-NGGPDDLCPQFQNIPAHYSPRTSPIMSP 222
P L P+SS + S + SP TSPC SP + GP P P +P +P
Sbjct: 1022 PQHLQPSSSSGLGT--SPSSSPRTSPCQSPTISEGPVPSLP--------IRPSRAPSRTP 1071
Query: 223 RTSLAEDSCLGRHSPVPRPASRSSSPGAKRRHSCAEALVALPPGASPQRSRSPS--PQPS 280
A+ S + P P + P +R + A PQR PS QPS
Sbjct: 1072 GPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPS 1131
Query: 281 SHVAPQDHGSPAGY----PPVAGSAVIMDALNSLATDSPCGIPPK-MWKTS--------- 326
G PAGY P + A ++ A S A S + P+ KTS
Sbjct: 1132 PQAGLAGPG-PAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFL 1190
Query: 327 PDP-SPVSAAPSKAGLP----RHIYPAVEFLGPCEQGERRNSAPESILLVPPTWPKPLVP 381
P+P P +A P ++ LP R P V P Q S P+ L P P+P
Sbjct: 1191 PEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQ-----SGPQPNLETP---PQPPPR 1242
Query: 382 AIPICSIPVTASLPPLEWPLSSQSGSYELRIEVQP 416
+ S+P AS P G E +++ P
Sbjct: 1243 SRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDP 1277
>gi|41281612 zinc finger protein 828 [Homo sapiens]
Length = 812
Score = 50.8 bits (120), Expect = 6e-06
Identities = 75/331 (22%), Positives = 112/331 (33%), Gaps = 28/331 (8%)
Query: 99 SAAKPAGASGLSPRIEITPSHELIQAVGPLRMRDAGLLVEQPPLAGVAASPRFTLPVPGF 158
++A+P LS + +L + P + L +P G SP P+P
Sbjct: 120 NSAEPKSIPALSMETQ-----KLGSVLSPESPKPTPLTPLEPQKPGSVVSPELQTPLPSP 174
Query: 159 EGYREPLCLSPASSGSSASFISDTFSPYTSP-CVSPNNGGPDDLCPQFQNIPAHYSPRTS 217
E + SP S S +P SP P P+ + N
Sbjct: 175 EPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFP 234
Query: 218 PIMSPRTSLAEDSCLGRHSPVPRPASRSSSPGAKRRHSCAEALVALPPGASPQRSRSPSP 277
+ P ++ + +S + SP P S ++SP +++ A P P S SP P
Sbjct: 235 ETLGPPSASSPESPVLAASPEPWGPSPAASPESRK-----SARTTSPEPRKPSPSESPEP 289
Query: 278 -QPSSHVAPQDHG-----SPAGYPPVAGSAVIMDALNSLATDSPC-------GIPPKMWK 324
+P V+P+ SP + P + N A+ P + P WK
Sbjct: 290 WKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWK 349
Query: 325 TSPDPSPVSAAP----SKAGLPRHIYPAVEFLGPCEQGERRNSAPESILLVPPTWPKPLV 380
P SP P S A + P E S P + PT
Sbjct: 350 PIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHW 409
Query: 381 PAIPICSIPVTASLPPLEWPLSSQSGSYELR 411
A+P S + PPL + S +GS ELR
Sbjct: 410 KAVPPVSPELRKPGPPLSPEIRSPAGSPELR 440
Score = 41.2 bits (95), Expect = 0.005
Identities = 81/361 (22%), Positives = 117/361 (32%), Gaps = 40/361 (11%)
Query: 4 PERQPQPDGGDAPGHEPGGSPQDELDFSILFDYEYLNPNEEEPNAHKVASPPSGPAYPDD 63
PE Q P P P S + + S+L +P +P P P P
Sbjct: 112 PEHQKIPCNSAEPKSIPALSMETQKLGSVL------SPESPKPTP----LTPLEPQKPGS 161
Query: 64 VLDYGLK-------PYSPLASLSGEPPGRFG--EPDRVGPQKFLSAAKPAGASGLSPRIE 114
V+ L+ P P + S EPP E ++ P KPA S S +
Sbjct: 162 VVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKAT 221
Query: 115 ITPSHELIQAVGPLRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGYREPLCLSPASSGS 174
++ Q+ P + + P+ + P P E + SP
Sbjct: 222 LSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSPEPRKP 281
Query: 175 SASFISDTFSPYTS---------PCVSPNN---GGPDDLCPQFQNIPAHYSPRTSPIMSP 222
S S + + P+ + P VSP + G P P N A P +P
Sbjct: 282 SPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAP 341
Query: 223 RTSLAEDSCLGRHSPVPRPASRSSSPGAKRRHSCAEALVALPPGASPQRSRSPSPQPSSH 282
S + SP P + S S + + S + + PP ASP+ +S P+
Sbjct: 342 SVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPP-ASPESWKSGPPELRKT 400
Query: 283 VAPQDHGSPAGYPPVAGSAVIMDALNSLATDSPCGIP--------PKMWKTSPDPSPVSA 334
PPV+ S SP G P P +WK SPD S
Sbjct: 401 APTLSPEHWKAVPPVSPELRKPGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTSP 460
Query: 335 A 335
A
Sbjct: 461 A 461
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.132 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,281,568
Number of Sequences: 37866
Number of extensions: 2834038
Number of successful extensions: 11629
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 47
Number of HSP's successfully gapped in prelim test: 634
Number of HSP's that attempted gapping in prelim test: 9500
Number of HSP's gapped (non-prelim): 2256
length of query: 925
length of database: 18,247,518
effective HSP length: 112
effective length of query: 813
effective length of database: 14,006,526
effective search space: 11387305638
effective search space used: 11387305638
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.