Guide to the Human Genome
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Search of human proteins with 27735047

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|27735047 DCN1, defective in cullin neddylation 1, domain
containing 3 [Homo sapiens]
         (304 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|27735047 DCN1, defective in cullin neddylation 1, domain cont...   630   0.0  
gi|62122952 DCN1, defective in cullin neddylation 1, domain cont...   171   6e-43
gi|36030883 RP42 homolog [Homo sapiens]                               167   1e-41
gi|14150015 DCN1, defective in cullin neddylation 1, domain cont...   114   1e-25
gi|94536778 DCN1, defective in cullin neddylation 1, domain cont...   111   7e-25
gi|94536780 DCN1, defective in cullin neddylation 1, domain cont...    94   2e-19
gi|20986488 YY1-associated protein isoform 2 [Homo sapiens]            33   0.24 
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]         33   0.41 
gi|239755027 PREDICTED: hypothetical protein [Homo sapiens]            32   0.70 
gi|239749540 PREDICTED: hypothetical protein [Homo sapiens]            32   0.70 
gi|239743690 PREDICTED: hypothetical protein XP_002342947 [Homo ...    32   0.70 
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        32   0.70 
gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]             32   0.91 
gi|239752490 PREDICTED: similar to Mucin-12 [Homo sapiens]             32   0.91 
gi|116089333 kelch domain containing 7A [Homo sapiens]                 32   0.91 
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    30   2.0  
gi|58761548 tau tubulin kinase 1 [Homo sapiens]                        30   2.0  
gi|33457336 chromosome 14 open reading frame 4 [Homo sapiens]          30   2.0  
gi|60097902 filaggrin [Homo sapiens]                                   30   2.6  
gi|119220552 sidekick 1 [Homo sapiens]                                 30   3.5  
gi|239750483 PREDICTED: similar to zinc finger protein 165 [Homo...    29   4.5  
gi|169205887 PREDICTED: similar to zinc finger protein 165 [Homo...    29   4.5  
gi|83715968 sarcoma antigen NY-SAR-79 [Homo sapiens]                   29   4.5  
gi|149944593 hypothetical protein LOC23349 [Homo sapiens]              29   4.5  
gi|31543559 radial spoke 3 homolog [Homo sapiens]                      29   5.9  
gi|9966761 choroideremia isoform a [Homo sapiens]                      29   5.9  
gi|190885493 hypothetical protein LOC84984 [Homo sapiens]              29   5.9  
gi|239743649 PREDICTED: IQ motif and ankyrin repeat domain-conta...    28   7.7  
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    28   7.7  
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1...    28   7.7  

>gi|27735047 DCN1, defective in cullin neddylation 1, domain
           containing 3 [Homo sapiens]
          Length = 304

 Score =  630 bits (1626), Expect = 0.0
 Identities = 304/304 (100%), Positives = 304/304 (100%)

Query: 1   MGQCVTKCKNPSSTLGSKNGDREPSNKSHSRRGAGHREEQVPPCGKPGGDILVNGTKKAE 60
           MGQCVTKCKNPSSTLGSKNGDREPSNKSHSRRGAGHREEQVPPCGKPGGDILVNGTKKAE
Sbjct: 1   MGQCVTKCKNPSSTLGSKNGDREPSNKSHSRRGAGHREEQVPPCGKPGGDILVNGTKKAE 60

Query: 61  AATEACQLPTSSGDAGRESKSNAEESSLQRLEELFRRYKDEREDAILEEGMERFCNDLCV 120
           AATEACQLPTSSGDAGRESKSNAEESSLQRLEELFRRYKDEREDAILEEGMERFCNDLCV
Sbjct: 61  AATEACQLPTSSGDAGRESKSNAEESSLQRLEELFRRYKDEREDAILEEGMERFCNDLCV 120

Query: 121 DPTEFRVLLLAWKFQAATMCKFTRKEFFDGCKAISADSIDGICARFPSLLTEAKQEDKFK 180
           DPTEFRVLLLAWKFQAATMCKFTRKEFFDGCKAISADSIDGICARFPSLLTEAKQEDKFK
Sbjct: 121 DPTEFRVLLLAWKFQAATMCKFTRKEFFDGCKAISADSIDGICARFPSLLTEAKQEDKFK 180

Query: 181 DLYRFTFQFGLDSEEGQRSLHREIAIALWKLVFTQNNPPVLDQWLNFLTENPSGIKGISR 240
           DLYRFTFQFGLDSEEGQRSLHREIAIALWKLVFTQNNPPVLDQWLNFLTENPSGIKGISR
Sbjct: 181 DLYRFTFQFGLDSEEGQRSLHREIAIALWKLVFTQNNPPVLDQWLNFLTENPSGIKGISR 240

Query: 241 DTWNMFLNFTQVIGPDLSNYSEDEAWPSLFDTFVEWEMERRKREGEGRGALSSGPEGLCP 300
           DTWNMFLNFTQVIGPDLSNYSEDEAWPSLFDTFVEWEMERRKREGEGRGALSSGPEGLCP
Sbjct: 241 DTWNMFLNFTQVIGPDLSNYSEDEAWPSLFDTFVEWEMERRKREGEGRGALSSGPEGLCP 300

Query: 301 EEQT 304
           EEQT
Sbjct: 301 EEQT 304


>gi|62122952 DCN1, defective in cullin neddylation 1, domain
           containing 2 [Homo sapiens]
          Length = 259

 Score =  171 bits (434), Expect = 6e-43
 Identities = 92/201 (45%), Positives = 126/201 (62%), Gaps = 8/201 (3%)

Query: 77  RESKSNAEESSLQRLEELFRRYKDER-EDAILEEGMERFCNDLCVDPTEFRVLLLAWKFQ 135
           RES  NA +   ++LE L+ RYKD + E+ I  +G+++FC+DL +DP    VL++AWKF+
Sbjct: 53  RESMRNAVDK--KKLERLYGRYKDPQDENKIGVDGIQQFCDDLSLDPASISVLVIAWKFR 110

Query: 136 AATMCKFTRKEFFDGCKAISADSIDGICARFPSLLTEAKQEDKFKDLYRFTFQFGLDSEE 195
           AAT C+F+RKEF DG   +  DS++ + A  P L  E K   KFKD Y+FTF F      
Sbjct: 111 AATQCEFSRKEFLDGMTELGCDSMEKLKALLPRLEQELKDTAKFKDFYQFTFTFA--KNP 168

Query: 196 GQRSLHREIAIALWKLVFTQNNPPVLDQWLNFLTENPSGIKGISRDTWNMFLNFTQVIGP 255
           GQ+ L  E+A+A WKLV +      LD W  FL E+    + I RDTWN+ L+F  +I  
Sbjct: 169 GQKGLDLEMAVAYWKLVLS-GRFKFLDLWNTFLMEHHK--RSIPRDTWNLLLDFGNMIAD 225

Query: 256 DLSNYSEDEAWPSLFDTFVEW 276
           D+SNY E+ AWP L D FVE+
Sbjct: 226 DMSNYDEEGAWPVLIDDFVEY 246


>gi|36030883 RP42 homolog [Homo sapiens]
          Length = 259

 Score =  167 bits (422), Expect = 1e-41
 Identities = 83/189 (43%), Positives = 122/189 (64%), Gaps = 6/189 (3%)

Query: 89  QRLEELFRRYKDER-EDAILEEGMERFCNDLCVDPTEFRVLLLAWKFQAATMCKFTRKEF 147
           ++LE+L+ RYKD + E+ I  +G+++FC+DL +DP    VL++AWKF+AAT C+F+++EF
Sbjct: 63  KKLEQLYNRYKDPQDENKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQEF 122

Query: 148 FDGCKAISADSIDGICARFPSLLTEAKQEDKFKDLYRFTFQFGLDSEEGQRSLHREIAIA 207
            DG   +  DSI+ + A+ P +  E K+  +FKD Y+FTF F      GQ+ L  E+AIA
Sbjct: 123 MDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFA--KNPGQKGLDLEMAIA 180

Query: 208 LWKLVFTQNNPPVLDQWLNFLTENPSGIKGISRDTWNMFLNFTQVIGPDLSNYSEDEAWP 267
            W LV        LD W  FL E+    + I +DTWN+ L+F+ +I  D+SNY E+ AWP
Sbjct: 181 YWNLVL-NGRFKFLDLWNKFLLEHHK--RSIPKDTWNLLLDFSTMIADDMSNYDEEGAWP 237

Query: 268 SLFDTFVEW 276
            L D FVE+
Sbjct: 238 VLIDDFVEF 246


>gi|14150015 DCN1, defective in cullin neddylation 1, domain
           containing 5 [Homo sapiens]
          Length = 237

 Score =  114 bits (284), Expect = 1e-25
 Identities = 60/179 (33%), Positives = 102/179 (56%), Gaps = 5/179 (2%)

Query: 103 EDAILEEGMERFCNDLCVDPTEFRVLLLAWKFQAATMCKFTRKEFFDGCKAISADSIDGI 162
           ++ +  EGME+FC D+ V+P    +L+LAWK +A +M  FT++E+  G  ++  D  + +
Sbjct: 62  DEVVGPEGMEKFCEDIGVEPENIIMLVLAWKLEAESMGFFTKEEWLKGMTSLQCDCTEKL 121

Query: 163 CARFPSLLTEAKQEDKFKDLYRFTFQFGLDSEEGQRSLHREIAIALWKLVFTQNNPPVLD 222
             +F  L ++      FK++YR+ F F  D +  QRSL  + A ++  L+  +   P+  
Sbjct: 122 QNKFDFLRSQLNDISSFKNIYRYAFDFARDKD--QRSLDIDTAKSMLALLLGR-TWPLFS 178

Query: 223 QWLNFLTENPSGIKGISRDTWNMFLNFTQVIGPDLSNYSEDEAWPSLFDTFVEWEMERR 281
            +  +L +  S  + +++D W   L F++ +  DLSNY ED AWP L D FVEW+  R+
Sbjct: 179 VFYQYLEQ--SKYRVMNKDQWYNVLEFSRTVHADLSNYDEDGAWPVLLDEFVEWQKVRQ 235


>gi|94536778 DCN1, defective in cullin neddylation 1, domain
           containing 4 isoform 1 [Homo sapiens]
          Length = 292

 Score =  111 bits (278), Expect = 7e-25
 Identities = 72/204 (35%), Positives = 103/204 (50%), Gaps = 10/204 (4%)

Query: 80  KSNAEESSLQRLEELFRRYKDEREDAILEEGMERFCNDLCVDPTEFRVLLLAWKFQAATM 139
           K+  E  S +R  E F  Y    +D +  EGME+FC D+ V+P    +L+LAWK  A  M
Sbjct: 95  KTEEEAFSSKRCLEWFYEYAGT-DDVVGPEGMEKFCEDIGVEPENVVMLVLAWKLDAQNM 153

Query: 140 CKFTRKEFFDGCKAISADSIDGICARFPSLLTEAKQEDKFKDLYRFTFQFGLDSEEGQRS 199
             FT +E+  G  ++  D+ + +      L +       FK +YR+ F F    E+ QRS
Sbjct: 154 GYFTLQEWLKGMTSLQCDTTEKLRNTLDYLRSFLNDSTNFKLIYRYAFDFA--REKDQRS 211

Query: 200 LHREIAIALWKLVFTQNNP--PVLDQWLNFLTENPSGIKGISRDTWNMFLNFTQVIGPDL 257
           L    A  +  L+  +  P  PV  Q+L       S  K I++D W   L F++ I  DL
Sbjct: 212 LDINTAKCMLGLLLGKIWPLFPVFHQFL-----EQSKYKVINKDQWCNVLEFSRTINLDL 266

Query: 258 SNYSEDEAWPSLFDTFVEWEMERR 281
           SNY ED AWP L D FVEW  +++
Sbjct: 267 SNYDEDGAWPVLLDEFVEWYKDKQ 290


>gi|94536780 DCN1, defective in cullin neddylation 1, domain
           containing 4 isoform 2 [Homo sapiens]
          Length = 257

 Score = 93.6 bits (231), Expect = 2e-19
 Identities = 60/202 (29%), Positives = 87/202 (43%), Gaps = 41/202 (20%)

Query: 80  KSNAEESSLQRLEELFRRYKDEREDAILEEGMERFCNDLCVDPTEFRVLLLAWKFQAATM 139
           K+  E  S +R  E F  Y    +D +  EGME+FC D+ V+P    +L+LAWK  A  M
Sbjct: 95  KTEEEAFSSKRCLEWFYEYAGT-DDVVGPEGMEKFCEDIGVEPENVVMLVLAWKLDAQNM 153

Query: 140 CKFTRKEFFDGCKAISADSIDGICARFPSLLTEAKQEDKFKDLYRFTFQFGLDSEEGQRS 199
             FT +E+  G  ++  D+ + +      L +       FK +YR+ F F   S+     
Sbjct: 154 GYFTLQEWLKGMTSLQCDTTEKLRNTLDYLRSFLNDSTNFKLIYRYAFDFARQSK----- 208

Query: 200 LHREIAIALWKLVFTQNNPPVLDQWLNFLTENPSGIKGISRDTWNMFLNFTQVIGPDLSN 259
                                               K I++D W   L F++ I  DLSN
Sbjct: 209 -----------------------------------YKVINKDQWCNVLEFSRTINLDLSN 233

Query: 260 YSEDEAWPSLFDTFVEWEMERR 281
           Y ED AWP L D FVEW  +++
Sbjct: 234 YDEDGAWPVLLDEFVEWYKDKQ 255


>gi|20986488 YY1-associated protein isoform 2 [Homo sapiens]
          Length = 796

 Score = 33.5 bits (75), Expect = 0.24
 Identities = 23/87 (26%), Positives = 42/87 (48%), Gaps = 4/87 (4%)

Query: 23  EPSNKSHSRRGAGHREEQVPPCGKPGGDILVNGTKKAEAATEACQLPTSSGDAGRESKSN 82
           E +++S +    G R  + PP  K  G  +  G +++ AAT +  LP +    G   +  
Sbjct: 3   EEASRSAAATNPGSRLTRWPPPDKREGSAVDPGKRRSLAATPSSSLPCTLIALGLRHEKE 62

Query: 83  AEESSLQRLEELFRRYKDEREDAILEE 109
           A E     +E+LF  ++DE   + +E+
Sbjct: 63  ANE----LMEDLFETFQDEMGFSNMED 85


>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
          Length = 953

 Score = 32.7 bits (73), Expect = 0.41
 Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 10/103 (9%)

Query: 7   KCKNPSSTLGS---KNGDREPSNKSHSRRGAGHREEQVPPCGKPGGDILVNGTKKAEAAT 63
           K  N S   GS   K+G R  S K   +RG   +    P       D     + ++++++
Sbjct: 847 KRPNTSPDRGSRDRKSGGRLGSPKPERQRGQNSKAPAAP------ADRKRQLSPQSKSSS 900

Query: 64  EACQLPTSSGDAGRESKSNAEESSLQRLEELFRRYKDEREDAI 106
           +   +P  + D G  S  + + S+L R EEL ++ K   EDAI
Sbjct: 901 KVTSVPGKASDPGAASTKSGKASTLSRREELLKQLK-AVEDAI 942


>gi|239755027 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 239

 Score = 32.0 bits (71), Expect = 0.70
 Identities = 21/75 (28%), Positives = 28/75 (37%), Gaps = 2/75 (2%)

Query: 14  TLGSKNGDREPSNKSHSRRGAGHREEQVPPCGKPGGDILVNGTKKAEAATEACQLP--TS 71
           TLG  +G  E       R G G       P G PG  +  +    AE   +  +LP    
Sbjct: 101 TLGRADGSWERPGLGTPRTGPGAERRPCLPQGVPGAKLSASDASVAETIIQRTKLPLLLQ 160

Query: 72  SGDAGRESKSNAEES 86
           + D GR +  N   S
Sbjct: 161 TADRGRRTSGNGPTS 175


>gi|239749540 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 239

 Score = 32.0 bits (71), Expect = 0.70
 Identities = 21/75 (28%), Positives = 28/75 (37%), Gaps = 2/75 (2%)

Query: 14  TLGSKNGDREPSNKSHSRRGAGHREEQVPPCGKPGGDILVNGTKKAEAATEACQLP--TS 71
           TLG  +G  E       R G G       P G PG  +  +    AE   +  +LP    
Sbjct: 101 TLGRADGSWERPGLGTPRTGPGAERRPCLPQGVPGAKLSASDASVAETIIQRTKLPLLLQ 160

Query: 72  SGDAGRESKSNAEES 86
           + D GR +  N   S
Sbjct: 161 TADRGRRTSGNGPTS 175


>gi|239743690 PREDICTED: hypothetical protein XP_002342947 [Homo
           sapiens]
          Length = 239

 Score = 32.0 bits (71), Expect = 0.70
 Identities = 21/75 (28%), Positives = 28/75 (37%), Gaps = 2/75 (2%)

Query: 14  TLGSKNGDREPSNKSHSRRGAGHREEQVPPCGKPGGDILVNGTKKAEAATEACQLP--TS 71
           TLG  +G  E       R G G       P G PG  +  +    AE   +  +LP    
Sbjct: 101 TLGRADGSWERPGLGTPRTGPGAERRPCLPQGVPGAKLSASDASVAETIIQRTKLPLLLQ 160

Query: 72  SGDAGRESKSNAEES 86
           + D GR +  N   S
Sbjct: 161 TADRGRRTSGNGPTS 175


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 32.0 bits (71), Expect = 0.70
 Identities = 23/78 (29%), Positives = 33/78 (42%), Gaps = 2/78 (2%)

Query: 10   NPSSTLGSKNGDREPSNKSHSRRGAGHREEQVPPCGKPGGDILVNGTKKAEAATEACQLP 69
            +P+ST  S  G  E S  SHSR G+ H          PG       +  +  +T+   LP
Sbjct: 3621 SPASTTSS--GVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLP 3678

Query: 70   TSSGDAGRESKSNAEESS 87
             S+  +G   +S    SS
Sbjct: 3679 ASTTTSGSSQESTTSHSS 3696



 Score = 31.6 bits (70), Expect = 0.91
 Identities = 23/78 (29%), Positives = 33/78 (42%), Gaps = 2/78 (2%)

Query: 10   NPSSTLGSKNGDREPSNKSHSRRGAGHREEQVPPCGKPGGDILVNGTKKAEAATEACQLP 69
            +P+ST  S  G  E S  SHSR G+ H          PG       +  +  +T+   LP
Sbjct: 2064 SPASTTSS--GVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLP 2121

Query: 70   TSSGDAGRESKSNAEESS 87
             S+  +G   +S    SS
Sbjct: 2122 ASTTTSGPSQESTTSHSS 2139



 Score = 30.8 bits (68), Expect = 1.6
 Identities = 22/86 (25%), Positives = 37/86 (43%), Gaps = 4/86 (4%)

Query: 6    TKCKNPSSTLG----SKNGDREPSNKSHSRRGAGHREEQVPPCGKPGGDILVNGTKKAEA 61
            T  ++P +TL     + +G  E S+ SHS+ G+ H          PG       +  +  
Sbjct: 2528 TSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPG 2587

Query: 62   ATEACQLPTSSGDAGRESKSNAEESS 87
            +T+   LP S+  +G   +S    SS
Sbjct: 2588 STDTTLLPASTTTSGPSQESTTSHSS 2613



 Score = 28.5 bits (62), Expect = 7.7
 Identities = 22/78 (28%), Positives = 32/78 (41%), Gaps = 2/78 (2%)

Query: 10   NPSSTLGSKNGDREPSNKSHSRRGAGHREEQVPPCGKPGGDILVNGTKKAEAATEACQLP 69
            +P+ST  S  G  E S  S SR G+ H          PG       +  +  +T+   LP
Sbjct: 981  SPASTTSS--GVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLP 1038

Query: 70   TSSGDAGRESKSNAEESS 87
             S+  +G   +S    SS
Sbjct: 1039 ASTTTSGPSQESTTSHSS 1056


>gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]
          Length = 587

 Score = 31.6 bits (70), Expect = 0.91
 Identities = 23/78 (29%), Positives = 33/78 (42%), Gaps = 2/78 (2%)

Query: 10  NPSSTLGSKNGDREPSNKSHSRRGAGHREEQVPPCGKPGGDILVNGTKKAEAATEACQLP 69
           +P+ST  S  G  E S  SHSR G+ H          PG       +  +  +T+   LP
Sbjct: 140 SPASTTSS--GVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLP 197

Query: 70  TSSGDAGRESKSNAEESS 87
            S+  +G   +S    SS
Sbjct: 198 ASTTTSGPSQESTTSHSS 215


>gi|239752490 PREDICTED: similar to Mucin-12 [Homo sapiens]
          Length = 456

 Score = 31.6 bits (70), Expect = 0.91
 Identities = 23/78 (29%), Positives = 33/78 (42%), Gaps = 2/78 (2%)

Query: 10  NPSSTLGSKNGDREPSNKSHSRRGAGHREEQVPPCGKPGGDILVNGTKKAEAATEACQLP 69
           +P+ST  S  G  E S  SHSR G+ H          PG       +  +  +T+   LP
Sbjct: 34  SPASTTSS--GVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLP 91

Query: 70  TSSGDAGRESKSNAEESS 87
            S+  +G   +S    SS
Sbjct: 92  ASTTTSGPSQESTTSHSS 109


>gi|116089333 kelch domain containing 7A [Homo sapiens]
          Length = 777

 Score = 31.6 bits (70), Expect = 0.91
 Identities = 17/43 (39%), Positives = 21/43 (48%), Gaps = 6/43 (13%)

Query: 8   CKNPSS----TLGSKNGDREPSNKS--HSRRGAGHREEQVPPC 44
           C+NP        G+ + DR+P  K     R G G   EQVPPC
Sbjct: 97  CENPRGPYVLVTGATSTDRKPQRKGSGEERGGQGSDSEQVPPC 139


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 30.4 bits (67), Expect = 2.0
 Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 2/74 (2%)

Query: 12  SSTLGSKNGDREPSNKSHSRRGAGHREEQVPPCGKPGGDILVNGTKKAEAATEACQLPTS 71
           SS+    + D E   K   +   G      PP   P    L  GT+  + A E  Q   S
Sbjct: 264 SSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSL--GTQPPKKAVEKQQPVES 321

Query: 72  SGDAGRESKSNAEE 85
           S D+  ES S++EE
Sbjct: 322 SEDSSDESDSSSEE 335



 Score = 29.6 bits (65), Expect = 3.5
 Identities = 21/75 (28%), Positives = 29/75 (38%), Gaps = 8/75 (10%)

Query: 11  PSSTLGSKNGDREPSNKSHSRRGAGHREEQVPPCGKPGGDILVNGTKKAEAATEACQLPT 70
           PS    +K G  E SN S S   +   EE++   G P          +A  A     L  
Sbjct: 503 PSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSP--------RPQAPKANGTSALTA 554

Query: 71  SSGDAGRESKSNAEE 85
            +G A + S+   EE
Sbjct: 555 QNGKAAKNSEEEEEE 569


>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
          Length = 1321

 Score = 30.4 bits (67), Expect = 2.0
 Identities = 23/77 (29%), Positives = 32/77 (41%), Gaps = 11/77 (14%)

Query: 11   PSSTLGSKNGDREPSNKSHSRRGAGHREEQ----------VPPC-GKPGGDILVNGTKKA 59
            P+ST  ++N    P ++S SRR +     Q          VPP   +P G     G+KK 
Sbjct: 1236 PASTSAARNASASPRSQSLSRRESPSPSHQARPGVPPPRGVPPARAQPDGTPSPGGSKKG 1295

Query: 60   EAATEACQLPTSSGDAG 76
                   Q  T+ G AG
Sbjct: 1296 PRGKLQAQRATTKGRAG 1312


>gi|33457336 chromosome 14 open reading frame 4 [Homo sapiens]
          Length = 796

 Score = 30.4 bits (67), Expect = 2.0
 Identities = 28/101 (27%), Positives = 37/101 (36%), Gaps = 5/101 (4%)

Query: 35  GHREEQVP-PCGKPGGDILVNGTKKAEAATEACQLPTSSGDA----GRESKSNAEESSLQ 89
           G R    P P G PGG   + GT    A + +    TSS  A    G   K     SS  
Sbjct: 280 GSRGPPTPAPPGAPGGPACLGGTPGVSATSSSASSSTSSSVAEVGVGAGGKRPGSVSSTD 339

Query: 90  RLEELFRRYKDEREDAILEEGMERFCNDLCVDPTEFRVLLL 130
           +  EL  + ++    A L E +     +    P   R  LL
Sbjct: 340 QERELKEKQRNAEALAELSESLRNRAEEWASKPKMVRDTLL 380


>gi|60097902 filaggrin [Homo sapiens]
          Length = 4061

 Score = 30.0 bits (66), Expect = 2.6
 Identities = 19/72 (26%), Positives = 28/72 (38%)

Query: 16   GSKNGDREPSNKSHSRRGAGHREEQVPPCGKPGGDILVNGTKKAEAATEACQLPTSSGDA 75
            GS  G R+  +  HS   +GH           G      G   + +A+   +    SGD+
Sbjct: 3115 GSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDS 3174

Query: 76   GRESKSNAEESS 87
             R S S   E+S
Sbjct: 3175 SRHSVSRHHEAS 3186



 Score = 29.6 bits (65), Expect = 3.5
 Identities = 19/72 (26%), Positives = 27/72 (37%)

Query: 16   GSKNGDREPSNKSHSRRGAGHREEQVPPCGKPGGDILVNGTKKAEAATEACQLPTSSGDA 75
            GS  G R+  +  HS   +GH           G      G   + +A+   +    SGD 
Sbjct: 2791 GSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDG 2850

Query: 76   GRESKSNAEESS 87
             R S S   E+S
Sbjct: 2851 SRHSGSRHHEAS 2862



 Score = 29.3 bits (64), Expect = 4.5
 Identities = 20/74 (27%), Positives = 29/74 (39%)

Query: 16  GSKNGDREPSNKSHSRRGAGHREEQVPPCGKPGGDILVNGTKKAEAATEACQLPTSSGDA 75
           GS  G R+ S+   S   +GH           G     +G   + +A+   +    SGD 
Sbjct: 521 GSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDG 580

Query: 76  GRESKSNAEESSLQ 89
            R S S   E+S Q
Sbjct: 581 TRHSGSRHHEASSQ 594



 Score = 29.3 bits (64), Expect = 4.5
 Identities = 20/74 (27%), Positives = 29/74 (39%)

Query: 16   GSKNGDREPSNKSHSRRGAGHREEQVPPCGKPGGDILVNGTKKAEAATEACQLPTSSGDA 75
            GS+ G R+ S    S   +GH           G     +G   + +A+   +    SGD 
Sbjct: 3763 GSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDG 3822

Query: 76   GRESKSNAEESSLQ 89
             R S S   E+S Q
Sbjct: 3823 SRHSGSRHHEASTQ 3836


>gi|119220552 sidekick 1 [Homo sapiens]
          Length = 2213

 Score = 29.6 bits (65), Expect = 3.5
 Identities = 36/127 (28%), Positives = 49/127 (38%), Gaps = 38/127 (29%)

Query: 10   NPSSTLGSKNGDREPSNKSHSRRGAGHREEQVPPCGKPGGDILVNGTKKAEAATEACQLP 69
            N  ST   KNG R P   S    G  + +E +  C K  G +L          TE+  L 
Sbjct: 2072 NVKSTFSKKNGTRSPPRPSPG--GLHYSDEDI--CNKYNGAVL----------TESVSLK 2117

Query: 70   TSSGDAGRESKSNAEESSLQRLEELFRRYKDEREDAILEEGMERFCNDLCVDPTEFRVLL 129
              S DA   S+S A +S              + EDA+ +     F N    DPT +    
Sbjct: 2118 EKSADA---SESEATDS--------------DYEDALPKHS---FVNHYMSDPTYYN--- 2154

Query: 130  LAWKFQA 136
             +WK +A
Sbjct: 2155 -SWKRRA 2160


>gi|239750483 PREDICTED: similar to zinc finger protein 165 [Homo
           sapiens]
          Length = 188

 Score = 29.3 bits (64), Expect = 4.5
 Identities = 15/46 (32%), Positives = 20/46 (43%), Gaps = 1/46 (2%)

Query: 1   MGQCVTKCKNPSSTLGSKNGDREPSNKSHSRRGAGHREEQVPPCGK 46
           M  C  + KN +   G K     P++ SHS    G +    P CGK
Sbjct: 78  MQSCTVETKNKNHQSG-KTSAPPPNSGSHSSSTTGEKSHTCPKCGK 122


>gi|169205887 PREDICTED: similar to zinc finger protein 165 [Homo
           sapiens]
          Length = 188

 Score = 29.3 bits (64), Expect = 4.5
 Identities = 15/46 (32%), Positives = 20/46 (43%), Gaps = 1/46 (2%)

Query: 1   MGQCVTKCKNPSSTLGSKNGDREPSNKSHSRRGAGHREEQVPPCGK 46
           M  C  + KN +   G K     P++ SHS    G +    P CGK
Sbjct: 78  MQSCTVETKNKNHQSG-KTAAPPPNSGSHSSSTTGEKSHTCPKCGK 122


>gi|83715968 sarcoma antigen NY-SAR-79 [Homo sapiens]
          Length = 1079

 Score = 29.3 bits (64), Expect = 4.5
 Identities = 17/48 (35%), Positives = 27/48 (56%), Gaps = 7/48 (14%)

Query: 79  SKSNAEESSLQRLEELFRRYKDEREDAILEEGMERFCNDLCVDPTEFR 126
           +  N+E S+ +    + ++Y  E+E  I EE ME FC+D     TE+R
Sbjct: 401 NNENSEMSTEKSENTIIQKYNTEQE--IREENMENFCSD-----TEYR 441


>gi|149944593 hypothetical protein LOC23349 [Homo sapiens]
          Length = 400

 Score = 29.3 bits (64), Expect = 4.5
 Identities = 28/110 (25%), Positives = 38/110 (34%), Gaps = 17/110 (15%)

Query: 53  VNGTKKAEAATEACQLPTSSGDAGRE---SKSNAEESSLQRLEEL--------FRRYKDE 101
           V   K+AEA T   Q  +S+G A  E        E     R             R+  D+
Sbjct: 55  VQEEKEAEAGTSVVQEESSAGRAAWERLRDGRGVEPEEFDRTSRFTPPAFIRPTRKLDDD 114

Query: 102 REDAILEEGMERFCNDLCVDPTEFRVLLLAWKFQAATMCKFTRKEFFDGC 151
           +   I  E  E   ND   D  E       W  ++   C+   + F DGC
Sbjct: 115 KPPEICLEPREPVVNDEMCDVCE------VWTAESLFPCRVCTRVFHDGC 158


>gi|31543559 radial spoke 3 homolog [Homo sapiens]
          Length = 560

 Score = 28.9 bits (63), Expect = 5.9
 Identities = 12/26 (46%), Positives = 19/26 (73%)

Query: 78  ESKSNAEESSLQRLEELFRRYKDERE 103
           E   N+E + +QRLEE  RR+++E+E
Sbjct: 350 EELRNSERAEVQRLEEQERRHREEKE 375


>gi|9966761 choroideremia isoform a [Homo sapiens]
          Length = 653

 Score = 28.9 bits (63), Expect = 5.9
 Identities = 22/82 (26%), Positives = 37/82 (45%), Gaps = 6/82 (7%)

Query: 8   CKNPSSTLGSKNGDREPSNKSHSRRGAGHREEQVPPCGKPGGDILVNGTKKAEAATEACQ 67
           C  P   LG+ N  ++              E+  PP   P  DI+++G      A+E+  
Sbjct: 575 CSGPDCGLGNDNAVKQAETLFQE---ICPNEDFCPPPPNPE-DIILDGDSLQPEASESSA 630

Query: 68  LPTSSGDAGRESKS--NAEESS 87
           +P ++ +  +ES +  N EESS
Sbjct: 631 IPEANSETFKESTNLGNLEESS 652


>gi|190885493 hypothetical protein LOC84984 [Homo sapiens]
          Length = 167

 Score = 28.9 bits (63), Expect = 5.9
 Identities = 16/45 (35%), Positives = 24/45 (53%)

Query: 80  KSNAEESSLQRLEELFRRYKDEREDAILEEGMERFCNDLCVDPTE 124
           KS  E+ SL++LE+LF   +       L E ME+   +  +DP E
Sbjct: 63  KSYLEQVSLRQLEKLFSFLRGYLSGQSLAETMEQIQRETTIDPEE 107


>gi|239743649 PREDICTED: IQ motif and ankyrin repeat
           domain-containing protein LOC642574 [Homo sapiens]
          Length = 580

 Score = 28.5 bits (62), Expect = 7.7
 Identities = 24/104 (23%), Positives = 41/104 (39%), Gaps = 13/104 (12%)

Query: 15  LGSKNGDREPSNKSHSRRGAGHREEQVPPCGKPGGDILVNGTKKAEAATEACQLPTSSGD 74
           L ++ G ++P      RRGAG     + P   PG         +A ++   C      G 
Sbjct: 29  LRARRGSQDPR-----RRGAGEVPADLGPLRVPGS--------RAASSCGLCGREPRLGR 75

Query: 75  AGRESKSNAEESSLQRLEELFRRYKDEREDAILEEGMERFCNDL 118
           AG      AE+ + + ++  FR+ +  RE A   E    +   +
Sbjct: 76  AGGFESRPAEDRAARAIQGAFRQLRARRELARRREERREYLEQM 119


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
           sapiens]
          Length = 2036

 Score = 28.5 bits (62), Expect = 7.7
 Identities = 22/78 (28%), Positives = 32/78 (41%), Gaps = 2/78 (2%)

Query: 10  NPSSTLGSKNGDREPSNKSHSRRGAGHREEQVPPCGKPGGDILVNGTKKAEAATEACQLP 69
           +P+ST  S  G  E S  S SR G+ H          PG       +  +  +T+   LP
Sbjct: 468 SPASTTSS--GVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLP 525

Query: 70  TSSGDAGRESKSNAEESS 87
            S+  +G   +S    SS
Sbjct: 526 ASTTTSGPSQESTTSHSS 543


>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
           [Homo sapiens]
          Length = 651

 Score = 28.5 bits (62), Expect = 7.7
 Identities = 22/104 (21%), Positives = 46/104 (44%), Gaps = 10/104 (9%)

Query: 5   VTKCKNPSSTLGSKNGDREPS-----NKSHSRRGAGHREEQVPPCGKPGGDILVNGTKKA 59
           +T   +  S L SK   ++       +K+ +++   + EE      +P GD     +KK 
Sbjct: 403 ITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGD-----SKKG 457

Query: 60  EAATEACQLPTSSGDAGRESKSNAEESSLQRLEELFRRYKDERE 103
           +   +  +  +   D  +++K NAE + ++   EL +  K  +E
Sbjct: 458 KKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHSKE 501


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.133    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,335,259
Number of Sequences: 37866
Number of extensions: 629525
Number of successful extensions: 2360
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 2302
Number of HSP's gapped (non-prelim): 68
length of query: 304
length of database: 18,247,518
effective HSP length: 102
effective length of query: 202
effective length of database: 14,385,186
effective search space: 2905807572
effective search space used: 2905807572
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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