Search of human proteins with 27597061

Search of human proteins with 27597061

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|27597061 ubiquitin protein ligase E3 component n-recognin 2
[Homo sapiens]
         (1755 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|27597061 ubiquitin protein ligase E3 component n-recognin 2 [...  3588   0.0  
gi|28372497 ubiquitin protein ligase E3 component n-recognin 1 [...  1651   0.0  
gi|160948610 E3 ubiquitin-protein ligase UBR3 [Homo sapiens]          153   2e-36
gi|187761324 shootin1 isoform a [Homo sapiens]                         38   0.076
gi|154354972 phosphatase and actin regulator 2 isoform 4 [Homo s...    37   0.13 
gi|154354974 phosphatase and actin regulator 2 isoform 3 [Homo s...    37   0.13 
gi|154354970 phosphatase and actin regulator 2 isoform 2 [Homo s...    37   0.13 
gi|154354968 phosphatase and actin regulator 2 isoform 1 [Homo s...    37   0.13 
gi|50511340 shootin1 isoform b [Homo sapiens]                          37   0.17 
gi|78042577 MAP7 domain containing 1 [Homo sapiens]                    37   0.22 
gi|27436951 lamin B2 [Homo sapiens]                                    36   0.38 
gi|239749462 PREDICTED: similar to ubiquitin protein ligase E3 c...    34   1.1  
gi|113420453 PREDICTED: similar to ubiquitin protein ligase E3 c...    34   1.1  
gi|34850061 superiorcervical ganglia, neural specific 10 [Homo s...    34   1.4  
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     34   1.4  
gi|42794779 myosin 18A isoform b [Homo sapiens]                        34   1.4  
gi|28416946 myosin 18A isoform a [Homo sapiens]                        34   1.4  
gi|109148542 alanyl-tRNA synthetase [Homo sapiens]                     33   2.4  
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]         33   3.2  
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]         33   3.2  
gi|4505257 moesin [Homo sapiens]                                       32   4.2  
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        32   4.2  
gi|32140182 keratin associated protein 10-10 [Homo sapiens]            32   4.2  
gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens]           32   4.2  
gi|30795240 aryl hydrocarbon receptor nuclear translocator isofo...    32   5.4  
gi|4502231 aryl hydrocarbon receptor nuclear translocator isofor...    32   5.4  
gi|4758128 doublecortin-like kinase 1 [Homo sapiens]                   32   5.4  
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]                32   7.1  
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]                32   7.1  
gi|31563524 myosin regulatory light chain 9 isoform b [Homo sapi...    32   7.1  

>gi|27597061 ubiquitin protein ligase E3 component n-recognin 2 [Homo
            sapiens]
          Length = 1755

 Score = 3588 bits (9305), Expect = 0.0
 Identities = 1755/1755 (100%), Positives = 1755/1755 (100%)

Query: 1    MASELEPEVQAIDRSLLECSAEEIAGKWLQATDLTREVYQHLAHYVPKIYCRGPNPFPQK 60
            MASELEPEVQAIDRSLLECSAEEIAGKWLQATDLTREVYQHLAHYVPKIYCRGPNPFPQK
Sbjct: 1    MASELEPEVQAIDRSLLECSAEEIAGKWLQATDLTREVYQHLAHYVPKIYCRGPNPFPQK 60

Query: 61   EDMLAQHVLLGPMEWYLCGEDPAFGFPKLEQANKPSHLCGRVFKVGEPTYSCRDCAVDPT 120
            EDMLAQHVLLGPMEWYLCGEDPAFGFPKLEQANKPSHLCGRVFKVGEPTYSCRDCAVDPT
Sbjct: 61   EDMLAQHVLLGPMEWYLCGEDPAFGFPKLEQANKPSHLCGRVFKVGEPTYSCRDCAVDPT 120

Query: 121  CVLCMECFLGSIHRDHRYRMTTSGGGGFCDCGDTEAWKEGPYCQKHELNTSEIEEEEDPL 180
            CVLCMECFLGSIHRDHRYRMTTSGGGGFCDCGDTEAWKEGPYCQKHELNTSEIEEEEDPL
Sbjct: 121  CVLCMECFLGSIHRDHRYRMTTSGGGGFCDCGDTEAWKEGPYCQKHELNTSEIEEEEDPL 180

Query: 181  VHLSEDVIARTYNIFAITFRYAVEILTWEKESELPADLEMVEKSDTYYCMLFNDEVHTYE 240
            VHLSEDVIARTYNIFAITFRYAVEILTWEKESELPADLEMVEKSDTYYCMLFNDEVHTYE
Sbjct: 181  VHLSEDVIARTYNIFAITFRYAVEILTWEKESELPADLEMVEKSDTYYCMLFNDEVHTYE 240

Query: 241  QVIYTLQKAVNCTQKEAIGFATTVDRDGRRSVRYGDFQYCEQAKSVIVRNTSRQTKPLKV 300
            QVIYTLQKAVNCTQKEAIGFATTVDRDGRRSVRYGDFQYCEQAKSVIVRNTSRQTKPLKV
Sbjct: 241  QVIYTLQKAVNCTQKEAIGFATTVDRDGRRSVRYGDFQYCEQAKSVIVRNTSRQTKPLKV 300

Query: 301  QVMHSSIVAHQNFGLKLLSWLGSIIGYSDGLRRILCQVGLQEGPDGENSSLVDRLMLSDS 360
            QVMHSSIVAHQNFGLKLLSWLGSIIGYSDGLRRILCQVGLQEGPDGENSSLVDRLMLSDS
Sbjct: 301  QVMHSSIVAHQNFGLKLLSWLGSIIGYSDGLRRILCQVGLQEGPDGENSSLVDRLMLSDS 360

Query: 361  KLWKGARSVYHQLFMSSLLMDLKYKKLFAVRFAKNYQQLQRDFMEDDHERAVSVTALSVQ 420
            KLWKGARSVYHQLFMSSLLMDLKYKKLFAVRFAKNYQQLQRDFMEDDHERAVSVTALSVQ
Sbjct: 361  KLWKGARSVYHQLFMSSLLMDLKYKKLFAVRFAKNYQQLQRDFMEDDHERAVSVTALSVQ 420

Query: 421  FFTAPTLARMLITEENLMSIIIKTFMDHLRHRDAQGRFQFERYTALQAFKFRRVQSLILD 480
            FFTAPTLARMLITEENLMSIIIKTFMDHLRHRDAQGRFQFERYTALQAFKFRRVQSLILD
Sbjct: 421  FFTAPTLARMLITEENLMSIIIKTFMDHLRHRDAQGRFQFERYTALQAFKFRRVQSLILD 480

Query: 481  LKYVLISKPTEWSDELRQKFLEGFDAFLELLKCMQGMDPITRQVGQHIEMEPEWEAAFTL 540
            LKYVLISKPTEWSDELRQKFLEGFDAFLELLKCMQGMDPITRQVGQHIEMEPEWEAAFTL
Sbjct: 481  LKYVLISKPTEWSDELRQKFLEGFDAFLELLKCMQGMDPITRQVGQHIEMEPEWEAAFTL 540

Query: 541  QMKLTHVISMMQDWCASDEKVLIEAYKKCLAVLMQCHGGYTDGEQPITLSICGHSVETIR 600
            QMKLTHVISMMQDWCASDEKVLIEAYKKCLAVLMQCHGGYTDGEQPITLSICGHSVETIR
Sbjct: 541  QMKLTHVISMMQDWCASDEKVLIEAYKKCLAVLMQCHGGYTDGEQPITLSICGHSVETIR 600

Query: 601  YCVSQEKVSIHLPVSRLLAGLHVLLSKSEVAYKFPELLPLSELSPPMLIEHPLRCLVLCA 660
            YCVSQEKVSIHLPVSRLLAGLHVLLSKSEVAYKFPELLPLSELSPPMLIEHPLRCLVLCA
Sbjct: 601  YCVSQEKVSIHLPVSRLLAGLHVLLSKSEVAYKFPELLPLSELSPPMLIEHPLRCLVLCA 660

Query: 661  QVHAGMWRRNGFSLVNQIYYYHNVKCRREMFDKDVVMLQTGVSMMDPNHFLMIMLSRFEL 720
            QVHAGMWRRNGFSLVNQIYYYHNVKCRREMFDKDVVMLQTGVSMMDPNHFLMIMLSRFEL
Sbjct: 661  QVHAGMWRRNGFSLVNQIYYYHNVKCRREMFDKDVVMLQTGVSMMDPNHFLMIMLSRFEL 720

Query: 721  YQIFSTPDYGKRFSSEITHKDVVQQNNTLIEEMLYLIIMLVGERFSPGVGQVNATDEIKR 780
            YQIFSTPDYGKRFSSEITHKDVVQQNNTLIEEMLYLIIMLVGERFSPGVGQVNATDEIKR
Sbjct: 721  YQIFSTPDYGKRFSSEITHKDVVQQNNTLIEEMLYLIIMLVGERFSPGVGQVNATDEIKR 780

Query: 781  EIIHQLSIKPMAHSELVKSLPEDENKETGMESVIEAVAHFKKPGLTGRGMYELKPECAKE 840
            EIIHQLSIKPMAHSELVKSLPEDENKETGMESVIEAVAHFKKPGLTGRGMYELKPECAKE
Sbjct: 781  EIIHQLSIKPMAHSELVKSLPEDENKETGMESVIEAVAHFKKPGLTGRGMYELKPECAKE 840

Query: 841  FNLYFYHFSRAEQSKAEEAQRKLKRQNREDTALPPPVLPPFCPLFASLVNILQSDVMLCI 900
            FNLYFYHFSRAEQSKAEEAQRKLKRQNREDTALPPPVLPPFCPLFASLVNILQSDVMLCI
Sbjct: 841  FNLYFYHFSRAEQSKAEEAQRKLKRQNREDTALPPPVLPPFCPLFASLVNILQSDVMLCI 900

Query: 901  MGTILQWAVEHNGYAWSESMLQRVLHLIGMALQEEKQHLENVTEEHVVTFTFTQKISKPG 960
            MGTILQWAVEHNGYAWSESMLQRVLHLIGMALQEEKQHLENVTEEHVVTFTFTQKISKPG
Sbjct: 901  MGTILQWAVEHNGYAWSESMLQRVLHLIGMALQEEKQHLENVTEEHVVTFTFTQKISKPG 960

Query: 961  EAPKNSPSILAMLETLQNAPYLEVHKDMIRWILKTFNAVKKMRESSPTSPVAETEGTIME 1020
            EAPKNSPSILAMLETLQNAPYLEVHKDMIRWILKTFNAVKKMRESSPTSPVAETEGTIME
Sbjct: 961  EAPKNSPSILAMLETLQNAPYLEVHKDMIRWILKTFNAVKKMRESSPTSPVAETEGTIME 1020

Query: 1021 ESSRDKDKAERKRKAEIARLRREKIMAQMSEMQRHFIDENKELFQQTLELDASTSAVLDH 1080
            ESSRDKDKAERKRKAEIARLRREKIMAQMSEMQRHFIDENKELFQQTLELDASTSAVLDH
Sbjct: 1021 ESSRDKDKAERKRKAEIARLRREKIMAQMSEMQRHFIDENKELFQQTLELDASTSAVLDH 1080

Query: 1081 SPVASDMTLTALGPAQTQVPEQRQFVTCILCQEEQEVKVESRAMVLAAFVQRSTVLSKNR 1140
            SPVASDMTLTALGPAQTQVPEQRQFVTCILCQEEQEVKVESRAMVLAAFVQRSTVLSKNR
Sbjct: 1081 SPVASDMTLTALGPAQTQVPEQRQFVTCILCQEEQEVKVESRAMVLAAFVQRSTVLSKNR 1140

Query: 1141 SKFIQDPEKYDPLFMHPDLSCGTHTSSCGHIMHAHCWQRYFDSVQAKEQRRQQRLRLHTS 1200
            SKFIQDPEKYDPLFMHPDLSCGTHTSSCGHIMHAHCWQRYFDSVQAKEQRRQQRLRLHTS
Sbjct: 1141 SKFIQDPEKYDPLFMHPDLSCGTHTSSCGHIMHAHCWQRYFDSVQAKEQRRQQRLRLHTS 1200

Query: 1201 YDVENGEFLCPLCECLSNTVIPLLLPPRNIFNNRLNFSDQPNLTQWIRTISQQIKALQFL 1260
            YDVENGEFLCPLCECLSNTVIPLLLPPRNIFNNRLNFSDQPNLTQWIRTISQQIKALQFL
Sbjct: 1201 YDVENGEFLCPLCECLSNTVIPLLLPPRNIFNNRLNFSDQPNLTQWIRTISQQIKALQFL 1260

Query: 1261 RKEESTPNNASTKNSENVDELQLPEGFRPDFRPKIPYSESIKEMLTTFGTATYKVGLKVH 1320
            RKEESTPNNASTKNSENVDELQLPEGFRPDFRPKIPYSESIKEMLTTFGTATYKVGLKVH
Sbjct: 1261 RKEESTPNNASTKNSENVDELQLPEGFRPDFRPKIPYSESIKEMLTTFGTATYKVGLKVH 1320

Query: 1321 PNEEDPRVPIMCWGSCAYTIQSIERILSDEDKPLFGPLPCRLDDCLRSLTRFAAAHWTVA 1380
            PNEEDPRVPIMCWGSCAYTIQSIERILSDEDKPLFGPLPCRLDDCLRSLTRFAAAHWTVA
Sbjct: 1321 PNEEDPRVPIMCWGSCAYTIQSIERILSDEDKPLFGPLPCRLDDCLRSLTRFAAAHWTVA 1380

Query: 1381 SVSVVQGHFCKLFASLVPNDSHEELPCILDIDMFHLLVGLVLAFPALQCQDFSGISLGTG 1440
            SVSVVQGHFCKLFASLVPNDSHEELPCILDIDMFHLLVGLVLAFPALQCQDFSGISLGTG
Sbjct: 1381 SVSVVQGHFCKLFASLVPNDSHEELPCILDIDMFHLLVGLVLAFPALQCQDFSGISLGTG 1440

Query: 1441 DLHIFHLVTMAHIIQILLTSCTEENGMDQENPPCEEESAVLALYKTLHQYTGSALKEIPS 1500
            DLHIFHLVTMAHIIQILLTSCTEENGMDQENPPCEEESAVLALYKTLHQYTGSALKEIPS
Sbjct: 1441 DLHIFHLVTMAHIIQILLTSCTEENGMDQENPPCEEESAVLALYKTLHQYTGSALKEIPS 1500

Query: 1501 GWHLWRSVRAGIMPFLKCSALFFHYLNGVPSPPDIQVPGTSHFEHLCSYLSLPNNLICLF 1560
            GWHLWRSVRAGIMPFLKCSALFFHYLNGVPSPPDIQVPGTSHFEHLCSYLSLPNNLICLF
Sbjct: 1501 GWHLWRSVRAGIMPFLKCSALFFHYLNGVPSPPDIQVPGTSHFEHLCSYLSLPNNLICLF 1560

Query: 1561 QENSEIMNSLIESWCRNSEVKRYLEGERDAIRYPRESNKLINLPEDYSSLINQASNFSCP 1620
            QENSEIMNSLIESWCRNSEVKRYLEGERDAIRYPRESNKLINLPEDYSSLINQASNFSCP
Sbjct: 1561 QENSEIMNSLIESWCRNSEVKRYLEGERDAIRYPRESNKLINLPEDYSSLINQASNFSCP 1620

Query: 1621 KSGGDKSRAPTLCLVCGSLLCSQSYCCQTELEGEDVGACTAHTYSCGSGVGIFLRVRECQ 1680
            KSGGDKSRAPTLCLVCGSLLCSQSYCCQTELEGEDVGACTAHTYSCGSGVGIFLRVRECQ
Sbjct: 1621 KSGGDKSRAPTLCLVCGSLLCSQSYCCQTELEGEDVGACTAHTYSCGSGVGIFLRVRECQ 1680

Query: 1681 VLFLAGKTKGCFYSPPYLDDYGETDQGLRRGNPLHLCKERFKKIQKLWHQHSVTEEIGHA 1740
            VLFLAGKTKGCFYSPPYLDDYGETDQGLRRGNPLHLCKERFKKIQKLWHQHSVTEEIGHA
Sbjct: 1681 VLFLAGKTKGCFYSPPYLDDYGETDQGLRRGNPLHLCKERFKKIQKLWHQHSVTEEIGHA 1740

Query: 1741 QEANQTLVGIDWQHL 1755
            QEANQTLVGIDWQHL
Sbjct: 1741 QEANQTLVGIDWQHL 1755


>gi|28372497 ubiquitin protein ligase E3 component n-recognin 1 [Homo
            sapiens]
          Length = 1749

 Score = 1651 bits (4276), Expect = 0.0
 Identities = 833/1752 (47%), Positives = 1168/1752 (66%), Gaps = 43/1752 (2%)

Query: 22   EEIAGKWLQATDLTREVYQHLAHYVPKIYCRGPNPFPQKEDMLAQHVLLGPMEWYLCGED 81
            + +A  W Q  D       HLA  VP+IY    +P  +K++   Q  +  P+EWYL GED
Sbjct: 23   QRLASWWDQQVDFYTAFLHHLAQLVPEIYFAEMDPDLEKQEESVQMSIFTPLEWYLFGED 82

Query: 82   PAFGFPKLEQANKPSHLCGRVFKVGEPTYSCRDCAVDPTCVLCMECFLGSIHRDHRYRMT 141
            P     KL+ +     LCGRVFK GE TYSCRDCA+DPTCVLCM+CF  S+H++HRY+M 
Sbjct: 83   PDICLEKLKHSGA-FQLCGRVFKSGETTYSCRDCAIDPTCVLCMDCFQDSVHKNHRYKMH 141

Query: 142  TSGGGGFCDCGDTEAWKEGPYCQKHELNTSEIEEEEDPLVHLSEDVIARTYNIFAITFRY 201
            TS GGGFCDCGDTEAWK GP+C  HE   +   +E      L+E+VI +   IF    +Y
Sbjct: 142  TSTGGGFCDCGDTEAWKTGPFCVNHEPGRAGTIKENSRCP-LNEEVIVQARKIFPSVIKY 200

Query: 202  AVEILTWEKESELPADLEMVEKSDTYYCMLFNDEVHTYEQVIYTLQKAVNCTQKEAIGFA 261
             VE+  WE+E ELP +L++ EK++ YYC+LFNDE H+Y+ VIY+LQ+A++C   EA    
Sbjct: 201  VVEMTIWEEEKELPPELQIREKNERYYCVLFNDEHHSYDHVIYSLQRALDCELAEAQLHT 260

Query: 262  TTVDRDGRRSVRYGDFQYCEQAKSVIVRNTSRQTK-PLKVQVMHSSIVAHQNFGLKLLSW 320
            T +D++GRR+V+ G +  C++AK  I  ++   ++ PL V+V+HS I+AHQ F L+L SW
Sbjct: 261  TAIDKEGRRAVKAGAYAACQEAKEDIKSHSENVSQHPLHVEVLHSEIMAHQKFALRLGSW 320

Query: 321  LGSIIGYSDGLRRILCQVGLQEGPDGENSSLVDRLMLSDSKLWKGARSVYHQLFMSSLLM 380
            +  I+ YS   R+I CQ  L+E PD EN  L+ RLML D+KL+KGAR + H+L  SS  M
Sbjct: 321  MNKIMSYSSDFRQIFCQACLREEPDSENPCLISRLMLWDAKLYKGARKILHELIFSSFFM 380

Query: 381  DLKYKKLFAVRFAKNYQQLQRDFMEDDHERAVSVTALSVQFFTAPTLARMLITEENLMSI 440
            +++YKKLFA+ F K Y+QLQ++++ DDH+R++S+TALSVQ FT PTLAR LI E+N++S+
Sbjct: 381  EMEYKKLFAMEFVKYYKQLQKEYISDDHDRSISITALSVQMFTVPTLARHLIEEQNVISV 440

Query: 441  IIKTFMDHL-RHRDAQGRFQFERYTALQAFKFRRVQSLILDLKYVLISKPTEWSDELRQK 499
            I +T ++ L  + D   +F F+ Y+     K  RV ++I DLKY+LISKPT W++ LR +
Sbjct: 441  ITETLLEVLPEYLDRNNKFNFQGYSQ---DKLGRVYAVICDLKYILISKPTIWTERLRMQ 497

Query: 500  FLEGFDAFLELLKCMQGMDPITRQVGQHIEMEPEWEAAFTLQMKLTHVISMMQDWCASDE 559
            FLEGF +FL++L CMQGM+ I RQVGQHIE++P+WEAA  +QM+L +++ M Q+WCA DE
Sbjct: 498  FLEGFRSFLKILTCMQGMEEIRRQVGQHIEVDPDWEAAIAIQMQLKNILLMFQEWCACDE 557

Query: 560  KVLIEAYKKCLAVLMQCHGGYTDGEQPITLSICGHSVETIRYCVSQEKVSIHLPVSRLLA 619
            ++L+ AYK+C   +M+C   +    + +  S CGHS+ET  Y VS++ VSIHLP+SR LA
Sbjct: 558  ELLLVAYKECHKAVMRCSTSFISSSKTVVQS-CGHSLETKSYRVSEDLVSIHLPLSRTLA 616

Query: 620  GLHVLLSKSEVAYKFPELLPLSELSPPMLIEHPLRCLVLCAQVHAGMWRRNGFSLVNQIY 679
            GLHV LS+     +  E +   +    +L+E+PLRCLVL AQV A MWRRNG SL++Q++
Sbjct: 617  GLHVRLSRLGAVSRLHEFVSFEDFQVEVLVEYPLRCLVLVAQVVAEMWRRNGLSLISQVF 676

Query: 680  YYHNVKCRREMFDKDVVMLQTGVSMMDPNHFLMIMLSRFELYQIFSTPDYGKRFSSEITH 739
            YY +VKCR EM+DKD++MLQ G S+MDPN FL+++L R+EL + F+     K  S++   
Sbjct: 677  YYQDVKCREEMYDKDIIMLQIGASLMDPNKFLLLVLQRYELAEAFN-----KTISTK--D 729

Query: 740  KDVVQQNNTLIEEMLYLIIMLVGERFSPGVGQVNATDEIKREIIHQLSIKPMAHSELVKS 799
            +D+++Q NTLIEEML ++I +VGER+ PGVG V   +   REIIH L I+PM HS + K+
Sbjct: 730  QDLIKQYNTLIEEMLQVLIYIVGERYVPGVGNVTKEEVTMREIIHLLCIEPMPHSAIAKN 789

Query: 800  LPEDENKETGMESVIEAVAHFKKPGLTGRGMYELKPECAKEFNLYFYHFSRAEQSKAEEA 859
            LPE+EN ETG+E+VI  VA FKKPG++G G+YELK E  K+FN+YFYH+S+ + SKAE  
Sbjct: 790  LPENENNETGLENVINKVATFKKPGVSGHGVYELKDESLKDFNMYFYHYSKTQHSKAEHM 849

Query: 860  QRKLKRQNREDTALPPPVLPPFCPLFASLVNILQSDVMLCIMGTILQWAVEHNGYAWSES 919
            Q+K ++Q  +D ALPPP  P FCP F+ ++N+L  D+M+ I+ T+ + A++ +   W+E 
Sbjct: 850  QKKRRKQENKDEALPPPPPPEFCPAFSKVINLLNCDIMMYILRTVFERAIDTDSNLWTEG 909

Query: 920  MLQRVLHLIGMALQEEKQHLENVTEEHVVTFTFTQKISKPGEAPKNSPSILAMLETLQNA 979
            MLQ   H++ + L EEKQ L+   EE V TF F  K S+ G +  N   I  +LE L+  
Sbjct: 910  MLQMAFHILALGLLEEKQQLQKAPEEEV-TFDFYHKASRLGSSAMN---IQMLLEKLKGI 965

Query: 980  PYLEVHKDMIRWILKTFNAVKKMRESSPTSPVAETEGTIM---EESSRDKDKAERKRKAE 1036
            P LE  KDMI WIL+ F+ VK++RE S    VA T G+     +E + DK+KAERKRKAE
Sbjct: 966  PQLEGQKDMITWILQMFDTVKRLREKSCLI-VATTSGSESIKNDEITHDKEKAERKRKAE 1024

Query: 1037 IARLRREKIMAQMSEMQRHFIDENKELFQQTLELDASTSAVLDH--SPVASDMTLTALGP 1094
             ARL R+KIMAQMS +Q++FI+ +K ++  T E+     ++++   +P  SD +  ALGP
Sbjct: 1025 AARLHRQKIMAQMSALQKNFIETHKLMYDNTSEMPGKEDSIMEEESTPAVSDYSRIALGP 1084

Query: 1095 AQTQVPEQRQFVTCILCQEEQEVKVESRAMVLAAFVQRSTVLSKNRSKFIQ-DPEKYDPL 1153
             +     +++ +TCILCQEEQEVK+E+ AMVL+A VQ+ST L+++R K I+   E  DPL
Sbjct: 1085 KRGPSVTEKEVLTCILCQEEQEVKIENNAMVLSACVQKSTALTQHRGKPIELSGEALDPL 1144

Query: 1154 FMHPDLSCGTHTSSCGHIMHAHCWQRYFDSVQAKEQRRQQRLRLHTS-YDVENGEFLCPL 1212
            FM PDL+ GT+T SCGH+MHA CWQ+YF++VQ   Q+R     +H   +D+E+GE+LCPL
Sbjct: 1145 FMDPDLAYGTYTGSCGHVMHAVCWQKYFEAVQLSSQQR-----IHVDLFDLESGEYLCPL 1199

Query: 1213 CECLSNTVIPLL-LPPRNIFNNRLNFSDQP-NLTQWIRTISQQIKALQFLRKEESTPNNA 1270
            C+ L NTVIP++ L P+ I +   +   Q   L +WI+T+  +I        +   P   
Sbjct: 1200 CKSLCNTVIPIIPLQPQKINSENADALAQLLTLARWIQTVLARISGYNIRHAKGENPIPI 1259

Query: 1271 STKNSENVDELQLPEGFRPDFRPKIPYSESIKEMLTTFGTATYKVGLKVHPNEEDPRVPI 1330
                      L+            I YS SIKEM+  F T  Y++GLKV P+E DPRVP+
Sbjct: 1260 FFNQGMGDSTLEFHSILSFGVESSIKYSNSIKEMVILFATTIYRIGLKVPPDERDPRVPM 1319

Query: 1331 MCWGSCAYTIQSIERILSDEDKPLFGPLPCRLDDCLRSLTRFAAAHWTVASVSVVQGHFC 1390
            + W +CA+TIQ+IE +L DE KPLFG L  R  + L++L +FA A        ++Q H  
Sbjct: 1320 LTWSTCAFTIQAIENLLGDEGKPLFGALQNRQHNGLKALMQFAVAQRITCPQVLIQKHLV 1379

Query: 1391 KLFASLVPNDSHEELPCILDIDMFHLLVGLVLAFPALQCQDF-----SGISLGTGDLHIF 1445
            +L + ++PN   E+ PC+L ID+FH+LVG VLAFP+L   D      S +S     L++F
Sbjct: 1380 RLLSVVLPNIKSEDTPCLLSIDLFHVLVGAVLAFPSLYWDDPVDLQPSSVSSSYNHLYLF 1439

Query: 1446 HLVTMAHIIQILLTSCTEENGMDQENPPCEEESAVLALYKTLHQYT-GSALKEIPSGWHL 1504
            HL+TMAH++QILLT  T    + Q     EE  +  + +  + QYT GS   +IP GW+L
Sbjct: 1440 HLITMAHMLQILLTVDTGLP-LAQVQEDSEEAHSASSFFAEISQYTSGSIGCDIP-GWYL 1497

Query: 1505 WRSVRAGIMPFLKCSALFFHYLNGVPSPPDIQVPGTS-HFEHLCSYLSLPNNLICLFQEN 1563
            W S++ GI P+L+C+ALFFHYL GV  P ++        +  LCSYLSLP NL  LFQE 
Sbjct: 1498 WVSLKNGITPYLRCAALFFHYLLGVTPPEELHTNSAEGEYSALCSYLSLPTNLFLLFQEY 1557

Query: 1564 SEIMNSLIESWCRNSEVKRYLEGERDAIRYPRESNKLINLPEDYSSLINQASNFSCPKSG 1623
             + +  L++ WC +  +   L+ +   +RYPR+ N LI LP+DYS L+NQAS+F CP+S 
Sbjct: 1558 WDTVRPLLQRWCADPALLNCLKQKNTVVRYPRKRNSLIELPDDYSCLLNQASHFRCPRSA 1617

Query: 1624 GDKSRAPTLCLVCGSLLCSQSYCCQTELEGEDVGACTAHTYSCGSGVGIFLRVRECQVLF 1683
             D+ + P LCL CG++LCSQ+ CCQ  + GE+VGAC  H   CG+GV IFL++REC+V+ 
Sbjct: 1618 DDERKHPVLCLFCGAILCSQNICCQEIVNGEEVGACIFHALHCGAGVCIFLKIRECRVVL 1677

Query: 1684 LAGKTKGCFYSPPYLDDYGETDQGLRRGNPLHLCKERFKKIQKLWHQHSVTEEIGHAQEA 1743
            + GK +GC Y  PYLD+YGETD GL+RGNPLHL +ER++K+  +W QH + EEI  +QE 
Sbjct: 1678 VEGKARGCAYPAPYLDEYGETDPGLKRGNPLHLSRERYRKLHLVWQQHCIIEEIARSQET 1737

Query: 1744 NQTLVGIDWQHL 1755
            NQ L G +WQ L
Sbjct: 1738 NQMLFGFNWQLL 1749


>gi|160948610 E3 ubiquitin-protein ligase UBR3 [Homo sapiens]
          Length = 1888

 Score =  153 bits (386), Expect = 2e-36
 Identities = 193/800 (24%), Positives = 322/800 (40%), Gaps = 162/800 (20%)

Query: 1008 TSPVAETEGTIMEESSRDKDKAERKRKAEIARLRREKIMAQMSEMQRHFIDENKELFQQT 1067
            T PV   + T  E+ + DK+  ER++KA   R R++K++A+ +  Q+ F++         
Sbjct: 1161 TPPVPPKKVTAAEKKTLDKE--ERRQKA---RERQQKLLAEFASRQKSFMET-------A 1208

Query: 1068 LELDASTSAVLDHSPVASDMTLTALGPAQTQVPEQRQFVTCILCQEEQEVKVESRAMVLA 1127
            +++D+  + +         M +T    A+ QV E      C++C +      E R   L 
Sbjct: 1209 MDVDSPENDI--------PMEITT---AEPQVSEA--VYDCVICGQSGPSS-EDRPTGLV 1254

Query: 1128 AFVQRSTVLSKNRSKF------IQDPEKYDP----LFMHP-----------DLSC----- 1161
              +Q S+VL + R         I + E+  P      +H            D SC     
Sbjct: 1255 VLLQASSVLGQCRDNVEPKKLPISEEEQIYPWDTCAAVHDVRLSLLQRYFKDSSCLLAVS 1314

Query: 1162 -----GTHTSSCGHIMHAHCWQRYFDSVQAKEQRRQQRLRLHTSYDVENGEFLCPLCECL 1216
                 G +  +CGH +H  C + Y +S+     R  Q L+    + V+ GEF CPLC   
Sbjct: 1315 IGWEGGVYVQTCGHTLHIDCHKSYMESL-----RNDQVLQ---GFSVDKGEFTCPLCRQF 1366

Query: 1217 SNTVIPLLLPPRNIFNNRLNFSDQPNLTQWIRTISQQIKALQFLRKEESTPNNASTKNSE 1276
            +N+V+P   P  N+ NN            W R  +   K++Q L KE             
Sbjct: 1367 ANSVLPCY-PGSNVENN-----------PWQRPSN---KSIQDLIKE------------- 1398

Query: 1277 NVDELQLPEGFRPDFRPKIPYSESIKEMLTTFGTATYKVGLKVHPNEEDPRVPIMCWGSC 1336
             V+ELQ   G  P    +   S+ ++ ++      T K           P    +   S 
Sbjct: 1399 -VEELQGRPGAFPS---ETNLSKEMESVMKDIKNTTQKKYRDYSKTPGSPDNDFLFMYSV 1454

Query: 1337 AYTIQSIERILSDEDKPLFGPLPCRLDDCLRSLTRFAAAHWTVASVSVVQGHFCKL--FA 1394
            A T   +E I    +    G        CL  L    A H  + S+      + KL    
Sbjct: 1455 ARTNLELELIHRGGNLCSGGASTAGKRSCLNQLFHVLALHMRLYSIDSEYNPWRKLTQLE 1514

Query: 1395 SLVPNDSHEE----LPCILDIDMFHLLVGLVLAFPA-LQCQDFSGISLGTGDLHIFHLVT 1449
             + P   +EE    +P IL  D+  LL+  +L  P  L+   F+ I      + +   + 
Sbjct: 1515 EMNPQLGYEEQQPEVP-ILYHDVTSLLLIQILMMPQPLRKDHFTCI------VKVLFTLL 1567

Query: 1450 MAHIIQILLTSCTEEN--------GMDQENPPCEEESAVLALYKTLHQYTGSALKEI--- 1498
                +  L   C+EE+         + +     E+   VL  +     + G    E    
Sbjct: 1568 YTQALAALSVKCSEEDRSAWKHAGALKKSTCDAEKSYEVLLSFVISELFKGKLYHEEGTQ 1627

Query: 1499 ------PSGWH---LWRSVRAGIMPFLKCSALFFHYLNGVPSPPDIQVPGTSHFEHLCSY 1549
                  P  W    + + ++   +PFL+ ++L  H+L G   P          F  L S 
Sbjct: 1628 ECAMVNPIAWSPESMEKCLQDFCLPFLRITSLLQHHLFGEDLP---SCQEEEEFSVLASC 1684

Query: 1550 LSLPNNLICLFQENSEIMNS-----------LIESWCRNSEVKRYLE--GERDAIRYPRE 1596
            L L   L   +Q     +++           +I  WC   E+K + E   E+      +E
Sbjct: 1685 LGL---LPTFYQTEHPFISASCLDWPVPAFDIITQWC--FEIKSFTERHAEQGKALLIQE 1739

Query: 1597 SN----KLINLPEDYSSLINQASNFSCPKSGGDKSRAPTLCLVCGSLLCSQSYCCQTELE 1652
            S      L+ LPE+Y+++       +C        + P +CLVCG+ +C +  CC+ +  
Sbjct: 1740 SKWKLPHLLQLPENYNTIFQYYHRKTCSVCT-KVPKDPAVCLVCGTFVCLKGLCCKQQSY 1798

Query: 1653 GEDVGACTAHTYSCGSGVGIFLRVRECQVLFLAGKTKGCFYSPPYLDDYGETDQGLRRGN 1712
             E    C  H+ +CG+G GIFL +    ++ + G  + C +   YLD +GE D+ LRRG 
Sbjct: 1799 CE----CVLHSQNCGAGTGIFLLINASVIIIIRGH-RFCLWGSVYLDAHGEEDRDLRRGK 1853

Query: 1713 PLHLCKERFKKIQKLWHQHS 1732
            PL++CKER+K +++ W  H+
Sbjct: 1854 PLYICKERYKVLEQQWISHT 1873



 Score =  124 bits (312), Expect = 6e-28
 Identities = 134/607 (22%), Positives = 255/607 (42%), Gaps = 86/607 (14%)

Query: 374 FMSSLLMDLKYKKLFAVRFAKNYQQLQRDFMEDDHERAVS--VTALSVQFFTAPTLARML 431
           F+ ++L D +YK  F   F ++Y  + +   +      +S  +  +SVQ F+   LAR +
Sbjct: 401 FLLNMLPDQEYKVAFTKTFVQHYAFIMKTLKKSHESDTMSNRIVHISVQLFSNEELARQV 460

Query: 432 ITEENLMSIIIKTFMDHLRHRDAQGRFQFERYTALQAFKFRRVQSLILDLKYVLISKPTE 491
             E  L+ I++   +  +     +   Q E  +            ++++    L+   T 
Sbjct: 461 TEECQLLDIMVTVLLYMMESCLIKSELQDEENSL----------HVVVNCGEALLKNNTY 510

Query: 492 WS-----------DELRQKFLEGFD---AFLELLKCMQGMDPITRQVGQHIEMEPE-WEA 536
           W              + ++FLE       ++  +   QGM+   R++ +H+E E + + A
Sbjct: 511 WPLVSDFINILSHQSVAKRFLEDHGLLVTWMNFVSFFQGMNLNKRELNEHVEFESQTYYA 570

Query: 537 AFTLQMKL-THVISMMQDWCASDE--KVLIEAYKKCLAVLMQCHGGYTDGEQPITLSICG 593
           AF  +++     +  +   C   E  +      + CL  L          ++P       
Sbjct: 571 AFAAELEACAQPMWGLLSHCKVRETQEYTRNVVRYCLEALQDWFDAINFVDEP------- 623

Query: 594 HSVETIRYCVSQEKVSIHLPVSRLLAGLHVLLSKSEVAYKFP--ELLPLSELSPPMLIEH 651
                     +  +V+ HLP+ R  A   + LSK+    +     +LP  E+   ++I H
Sbjct: 624 ----------APNQVTFHLPLHRYYA---MFLSKAVKCQELDLDSVLPDQEMLMKLMI-H 669

Query: 652 PLRCLVLCAQVHAGMWRRNGFSLVNQIYYYHNVKCRREMFDKDVVMLQTGVSMMDPNHFL 711
           PL+     A++H+ MW RNG  +  Q   Y        M D D+ +LQ   S +DP++F+
Sbjct: 670 PLQIQASLAEIHSNMWVRNGLQIKGQAMTYVQSHFCNSMIDPDIYLLQVCASRLDPDYFI 729

Query: 712 MIMLSRFELYQIFSTPDYGKRFSSEITHKDVVQQNNTLIEEMLYLIIMLVGERFSPGVGQ 771
             +  RF++  + +     +    +  H+       +++E  L  +++L+  R   G+  
Sbjct: 730 SSVFERFKVVDLLTMASQHQNTVLDAEHE------RSMLEGALTFLVILLSLRLHLGM-- 781

Query: 772 VNATDEIKR-EIIHQLSIKPMAHSELVKSLPEDENKETGM-------ESVIEAVAHFKKP 823
             + DEI R E++ QL +    HS L+  +PE+ N ++G+       ESV+ AVA FK P
Sbjct: 782 --SDDEILRAEMVAQLCMNDRTHSSLLDLIPENPNPKSGIIPGSYSFESVLSAVADFKAP 839

Query: 824 -----GLTGRGMYELKPEC-AKEFNLYFYHFSRAEQSKAEEAQRKLKRQNREDTALPPPV 877
                G   +GMY  K E   +EF+          +   + A  +     ++    P   
Sbjct: 840 VFEPGGSMQQGMYTPKAEVWDQEFDPVMVILRTVYRRDVQSAMDRYTAFLKQSGKFPGNP 899

Query: 878 LPPF------CPLFASLVNILQSDVMLCIMGTIL-QWAVEHNGYAWSESMLQRVLHLIGM 930
            PP+       P +  L+ +L    +  ++ T+L +  ++H     SE +L  VL+LI +
Sbjct: 900 WPPYKKRTSLHPSYKGLMRLLHCKTLHIVLFTLLYKILMDHQNL--SEHVLCMVLYLIEL 957

Query: 931 ALQEEKQ 937
            L+   +
Sbjct: 958 GLENSAE 964



 Score = 77.8 bits (190), Expect = 9e-14
 Identities = 41/122 (33%), Positives = 61/122 (50%), Gaps = 4/122 (3%)

Query: 73  MEWYLCGEDPAFGFPKL---EQANKPSHLCGRVFKVGEPTYSCRDCAVDPTCVLCMECFL 129
           +EW  C      G+ +     +A  P+ LCG V+      Y CR C + P   LC ECF 
Sbjct: 91  LEWCKCLLAGGGGYDEFCAAVRAYDPAALCGLVWTANFVAYRCRTCGISPCMSLCAECFH 150

Query: 130 GSIHRDHRYRMTTSGGGGFCDCGDTEAWKEGPYCQKHEL-NTSEIEEEEDPLVHLSEDVI 188
              H  H + M  S  GG CDCGD+   +E  +C++H++ ++S I      L+ +SE V+
Sbjct: 151 QGDHTGHDFNMFRSQAGGACDCGDSNVMRESGFCKRHQIKSSSNIPCVPKDLLMMSEFVL 210

Query: 189 AR 190
            R
Sbjct: 211 PR 212


>gi|187761324 shootin1 isoform a [Homo sapiens]
          Length = 631

 Score = 38.1 bits (87), Expect = 0.076
 Identities = 78/367 (21%), Positives = 135/367 (36%), Gaps = 59/367 (16%)

Query: 674  LVNQIYYYHNVKCRREMFDKDVVMLQTGVSMMDPNHFLMIMLSRFELYQIFSTPDYGKRF 733
            LV  I   + VK  + + + +V  L+    +   N   M+ +  +E  Q+    +   R 
Sbjct: 172  LVEVIEEVNKVKQEKTVLNSEV--LEQRKVLEKCNRVSMLAVEEYEEMQVNLELEKDLRK 229

Query: 734  SSEITHKDVVQQNNTLIEEMLYLIIMLVGERFSPGVGQVNATDEIKREIIHQLSIKPMAH 793
             +E   +++  + N L  +   L+   +     P    + A DE   ++  QL  + + H
Sbjct: 230  KAESFAQEMFIEQNKLKRQSHLLLQSSI-----PDQQLLKALDE-NAKLTQQLEEERIQH 283

Query: 794  SELVKSLPEDENKETGMESVIEAVAHFKKPGLTGRGMYELKPECAKEFNLYFYHFSRAEQ 853
             + VK L E    ET  + +     H  K  L      EL  E  KE  L + +     +
Sbjct: 284  QQKVKELEEQLENETLHKEI-----HNLKQQL------ELLEEDKKELELKYQNSEEKAR 332

Query: 854  SKAEEAQRKLKRQNREDTALPPPVLPPFCPLFASLVNILQSDVMLCIMGTILQWAVEHNG 913
            +         KR N+ + ++PPP  PP  PL     N ++S +                 
Sbjct: 333  NLKHSVDELQKRVNQSENSVPPPPPPP-PPLPPPPPNPIRSLM----------------- 374

Query: 914  YAWSESMLQRVLHLIGMALQEEKQHLENVTEEHVVTFTFTQKISKPGEAPKNSPSILAML 973
                 SM+++  H  G   ++EK      TEE  VT    Q + +  +  K    +  + 
Sbjct: 375  -----SMIRKRSHPSGSGAKKEKATQPETTEE--VTDLKRQAVEEMMDRIKKGVHLRPVN 427

Query: 974  ETLQNAPYLEVHK------DMIRWILKTFNAVKKMRESSPTSPVAETEGTIMEESSRDKD 1027
            +T +     E  K      D ++ IL T N     R      P         E S  + +
Sbjct: 428  QTARPKTKPESSKGCESAVDELKGILGTLNKSTSSRSLKSLDP---------ENSETELE 478

Query: 1028 KAERKRK 1034
            +  R+RK
Sbjct: 479  RILRRRK 485


>gi|154354972 phosphatase and actin regulator 2 isoform 4 [Homo
            sapiens]
          Length = 554

 Score = 37.4 bits (85), Expect = 0.13
 Identities = 82/384 (21%), Positives = 138/384 (35%), Gaps = 57/384 (14%)

Query: 787  SIKPMAHSELVKSLPEDENKETGMESVI-EAVAHFKKPGLTGRGMYELKPECAKEFNLYF 845
            S +P A  E V S         G      + +        T  G  +LK E A+      
Sbjct: 164  SSRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAE------ 217

Query: 846  YHFSRAEQSKAEEAQRKLKRQNR---EDTALPPPVLP------PFCPLFASLVNILQSDV 896
               +R E  K E+     + QN    +    PPPV P      P  PL    +    + V
Sbjct: 218  ---TRVESFKLEQTVPGAEEQNTGKFKSMVPPPPVAPAPSPLAPPLPLEDQCITASDTPV 274

Query: 897  MLCIMGTILQW-AVEHNGYAWSESMLQRVLHLIGMALQEEKQHLENVTEEHVVTFTFTQK 955
            +L  +G  L   A++ +   W+E    R     G  L   +++ +  T +  +  T  Q 
Sbjct: 275  VLVSVGADLPVSALDPSQLLWAEEPTNRTTLYSGTGLSVNRENAKCFTTKEELGKTVPQL 334

Query: 956  ISKPGEAPKNSPSILAMLETLQNAPYLEVHKDMIRWILKTFNAVKKMRESSPTSPVAETE 1015
            ++ PG   ++S S  A  +        E H++             +  +S    P+  T+
Sbjct: 335  LT-PGLMGESSESFSASED--------EGHREY------------QANDSDSDGPILYTD 373

Query: 1016 GTIMEESSRDKDKAERKRKAEIARLRREKIMAQMSEMQRHFIDENKELFQQTLELDASTS 1075
                E+   D+D +     A   R RR+ +  ++         E+K + Q+T E +    
Sbjct: 374  D---EDEDEDEDGSGESALASKIR-RRDTLAIKLGNRPSKKELEDKNILQRTSEEERQEI 429

Query: 1076 AVLDHSPVASDMTLTALGPAQTQVPEQRQFVTCILCQEEQEVKVE-----SRAMVL---A 1127
                   + + +         T+  EQR  +     +EEQE K+E     SR + L    
Sbjct: 430  ----RQQIGTKLVRRLSQRPTTEELEQRNILKQKNEEEEQEAKMELKRRLSRKLSLRPTV 485

Query: 1128 AFVQRSTVLSKNRSKFIQDPEKYD 1151
            A +Q   +L  N    + D   YD
Sbjct: 486  AELQARRILRFNEYVEVTDSPDYD 509


>gi|154354974 phosphatase and actin regulator 2 isoform 3 [Homo
            sapiens]
          Length = 634

 Score = 37.4 bits (85), Expect = 0.13
 Identities = 82/384 (21%), Positives = 138/384 (35%), Gaps = 57/384 (14%)

Query: 787  SIKPMAHSELVKSLPEDENKETGMESVI-EAVAHFKKPGLTGRGMYELKPECAKEFNLYF 845
            S +P A  E V S         G      + +        T  G  +LK E A+      
Sbjct: 244  SSRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAE------ 297

Query: 846  YHFSRAEQSKAEEAQRKLKRQNR---EDTALPPPVLP------PFCPLFASLVNILQSDV 896
               +R E  K E+     + QN    +    PPPV P      P  PL    +    + V
Sbjct: 298  ---TRVESFKLEQTVPGAEEQNTGKFKSMVPPPPVAPAPSPLAPPLPLEDQCITASDTPV 354

Query: 897  MLCIMGTILQW-AVEHNGYAWSESMLQRVLHLIGMALQEEKQHLENVTEEHVVTFTFTQK 955
            +L  +G  L   A++ +   W+E    R     G  L   +++ +  T +  +  T  Q 
Sbjct: 355  VLVSVGADLPVSALDPSQLLWAEEPTNRTTLYSGTGLSVNRENAKCFTTKEELGKTVPQL 414

Query: 956  ISKPGEAPKNSPSILAMLETLQNAPYLEVHKDMIRWILKTFNAVKKMRESSPTSPVAETE 1015
            ++ PG   ++S S  A  +        E H++             +  +S    P+  T+
Sbjct: 415  LT-PGLMGESSESFSASED--------EGHREY------------QANDSDSDGPILYTD 453

Query: 1016 GTIMEESSRDKDKAERKRKAEIARLRREKIMAQMSEMQRHFIDENKELFQQTLELDASTS 1075
                E+   D+D +     A   R RR+ +  ++         E+K + Q+T E +    
Sbjct: 454  D---EDEDEDEDGSGESALASKIR-RRDTLAIKLGNRPSKKELEDKNILQRTSEEERQEI 509

Query: 1076 AVLDHSPVASDMTLTALGPAQTQVPEQRQFVTCILCQEEQEVKVE-----SRAMVL---A 1127
                   + + +         T+  EQR  +     +EEQE K+E     SR + L    
Sbjct: 510  ----RQQIGTKLVRRLSQRPTTEELEQRNILKQKNEEEEQEAKMELKRRLSRKLSLRPTV 565

Query: 1128 AFVQRSTVLSKNRSKFIQDPEKYD 1151
            A +Q   +L  N    + D   YD
Sbjct: 566  AELQARRILRFNEYVEVTDSPDYD 589


>gi|154354970 phosphatase and actin regulator 2 isoform 2 [Homo
            sapiens]
          Length = 565

 Score = 37.4 bits (85), Expect = 0.13
 Identities = 82/384 (21%), Positives = 138/384 (35%), Gaps = 57/384 (14%)

Query: 787  SIKPMAHSELVKSLPEDENKETGMESVI-EAVAHFKKPGLTGRGMYELKPECAKEFNLYF 845
            S +P A  E V S         G      + +        T  G  +LK E A+      
Sbjct: 175  SSRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAE------ 228

Query: 846  YHFSRAEQSKAEEAQRKLKRQNR---EDTALPPPVLP------PFCPLFASLVNILQSDV 896
               +R E  K E+     + QN    +    PPPV P      P  PL    +    + V
Sbjct: 229  ---TRVESFKLEQTVPGAEEQNTGKFKSMVPPPPVAPAPSPLAPPLPLEDQCITASDTPV 285

Query: 897  MLCIMGTILQW-AVEHNGYAWSESMLQRVLHLIGMALQEEKQHLENVTEEHVVTFTFTQK 955
            +L  +G  L   A++ +   W+E    R     G  L   +++ +  T +  +  T  Q 
Sbjct: 286  VLVSVGADLPVSALDPSQLLWAEEPTNRTTLYSGTGLSVNRENAKCFTTKEELGKTVPQL 345

Query: 956  ISKPGEAPKNSPSILAMLETLQNAPYLEVHKDMIRWILKTFNAVKKMRESSPTSPVAETE 1015
            ++ PG   ++S S  A  +        E H++             +  +S    P+  T+
Sbjct: 346  LT-PGLMGESSESFSASED--------EGHREY------------QANDSDSDGPILYTD 384

Query: 1016 GTIMEESSRDKDKAERKRKAEIARLRREKIMAQMSEMQRHFIDENKELFQQTLELDASTS 1075
                E+   D+D +     A   R RR+ +  ++         E+K + Q+T E +    
Sbjct: 385  D---EDEDEDEDGSGESALASKIR-RRDTLAIKLGNRPSKKELEDKNILQRTSEEERQEI 440

Query: 1076 AVLDHSPVASDMTLTALGPAQTQVPEQRQFVTCILCQEEQEVKVE-----SRAMVL---A 1127
                   + + +         T+  EQR  +     +EEQE K+E     SR + L    
Sbjct: 441  ----RQQIGTKLVRRLSQRPTTEELEQRNILKQKNEEEEQEAKMELKRRLSRKLSLRPTV 496

Query: 1128 AFVQRSTVLSKNRSKFIQDPEKYD 1151
            A +Q   +L  N    + D   YD
Sbjct: 497  AELQARRILRFNEYVEVTDSPDYD 520


>gi|154354968 phosphatase and actin regulator 2 isoform 1 [Homo
            sapiens]
          Length = 645

 Score = 37.4 bits (85), Expect = 0.13
 Identities = 82/384 (21%), Positives = 138/384 (35%), Gaps = 57/384 (14%)

Query: 787  SIKPMAHSELVKSLPEDENKETGMESVI-EAVAHFKKPGLTGRGMYELKPECAKEFNLYF 845
            S +P A  E V S         G      + +        T  G  +LK E A+      
Sbjct: 255  SSRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAE------ 308

Query: 846  YHFSRAEQSKAEEAQRKLKRQNR---EDTALPPPVLP------PFCPLFASLVNILQSDV 896
               +R E  K E+     + QN    +    PPPV P      P  PL    +    + V
Sbjct: 309  ---TRVESFKLEQTVPGAEEQNTGKFKSMVPPPPVAPAPSPLAPPLPLEDQCITASDTPV 365

Query: 897  MLCIMGTILQW-AVEHNGYAWSESMLQRVLHLIGMALQEEKQHLENVTEEHVVTFTFTQK 955
            +L  +G  L   A++ +   W+E    R     G  L   +++ +  T +  +  T  Q 
Sbjct: 366  VLVSVGADLPVSALDPSQLLWAEEPTNRTTLYSGTGLSVNRENAKCFTTKEELGKTVPQL 425

Query: 956  ISKPGEAPKNSPSILAMLETLQNAPYLEVHKDMIRWILKTFNAVKKMRESSPTSPVAETE 1015
            ++ PG   ++S S  A  +        E H++             +  +S    P+  T+
Sbjct: 426  LT-PGLMGESSESFSASED--------EGHREY------------QANDSDSDGPILYTD 464

Query: 1016 GTIMEESSRDKDKAERKRKAEIARLRREKIMAQMSEMQRHFIDENKELFQQTLELDASTS 1075
                E+   D+D +     A   R RR+ +  ++         E+K + Q+T E +    
Sbjct: 465  D---EDEDEDEDGSGESALASKIR-RRDTLAIKLGNRPSKKELEDKNILQRTSEEERQEI 520

Query: 1076 AVLDHSPVASDMTLTALGPAQTQVPEQRQFVTCILCQEEQEVKVE-----SRAMVL---A 1127
                   + + +         T+  EQR  +     +EEQE K+E     SR + L    
Sbjct: 521  ----RQQIGTKLVRRLSQRPTTEELEQRNILKQKNEEEEQEAKMELKRRLSRKLSLRPTV 576

Query: 1128 AFVQRSTVLSKNRSKFIQDPEKYD 1151
            A +Q   +L  N    + D   YD
Sbjct: 577  AELQARRILRFNEYVEVTDSPDYD 600


>gi|50511340 shootin1 isoform b [Homo sapiens]
          Length = 456

 Score = 37.0 bits (84), Expect = 0.17
 Identities = 46/207 (22%), Positives = 82/207 (39%), Gaps = 19/207 (9%)

Query: 674 LVNQIYYYHNVKCRREMFDKDVVMLQTGVSMMDPNHFLMIMLSRFELYQIFSTPDYGKRF 733
           LV  I   + VK  + + + +V  L+    +   N   M+ +  +E  Q+    +   R 
Sbjct: 172 LVEVIEEVNKVKQEKTVLNSEV--LEQRKVLEKCNRVSMLAVEEYEEMQVNLELEKDLRK 229

Query: 734 SSEITHKDVVQQNNTLIEEMLYLIIMLVGERFSPGVGQVNATDEIKREIIHQLSIKPMAH 793
            +E   +++  + N L  +   L+   +     P    + A DE   ++  QL  + + H
Sbjct: 230 KAESFAQEMFIEQNKLKRQSHLLLQSSI-----PDQQLLKALDE-NAKLTQQLEEERIQH 283

Query: 794 SELVKSLPEDENKETGMESVIEAVAHFKKPGLTGRGMYELKPECAKEFNLYFYHFSRAEQ 853
            + VK L E    ET  + +     H  K  L      EL  E  KE  L + +     +
Sbjct: 284 QQKVKELEEQLENETLHKEI-----HNLKQQL------ELLEEDKKELELKYQNSEEKAR 332

Query: 854 SKAEEAQRKLKRQNREDTALPPPVLPP 880
           +         KR N+ + ++PPP  PP
Sbjct: 333 NLKHSVDELQKRVNQSENSVPPPPPPP 359


>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
          Length = 841

 Score = 36.6 bits (83), Expect = 0.22
 Identities = 16/46 (34%), Positives = 29/46 (63%)

Query: 1024 RDKDKAERKRKAEIARLRREKIMAQMSEMQRHFIDENKELFQQTLE 1069
            R+K   ER+R+ E  RL+ E+  A + E QR  +++NKE ++  ++
Sbjct: 171  REKQLQERRRRLEEQRLKAEQRRAALEERQRQKLEKNKERYEAAIQ 216


>gi|27436951 lamin B2 [Homo sapiens]
          Length = 600

 Score = 35.8 bits (81), Expect = 0.38
 Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 5/90 (5%)

Query: 1017 TIMEESSRDKDKAERKRKAEIARLRREKI---MAQMSEMQRHFIDENKELFQQTLELDAS 1073
            ++ EE  R+  +   +R  E+   R+++    MAQ  E  R   DE   L++  LEL+ +
Sbjct: 204  SVFEEEVRETRRRHERRLVEVDSSRQQEYDFKMAQALEELRSQHDEQVRLYK--LELEQT 261

Query: 1074 TSAVLDHSPVASDMTLTALGPAQTQVPEQR 1103
              A LD + ++SD    A   A+ ++ E R
Sbjct: 262  YQAKLDSAKLSSDQNDKAASAAREELKEAR 291


>gi|239749462 PREDICTED: similar to ubiquitin protein ligase E3
           component n-recognin 5 isoform 2 [Homo sapiens]
          Length = 2277

 Score = 34.3 bits (77), Expect = 1.1
 Identities = 12/47 (25%), Positives = 23/47 (48%), Gaps = 1/47 (2%)

Query: 105 VGEPTYSCRDCAVDPTCVLCMECFLGSIHRDHRYRMTTSGGGGFCDC 151
           + +  + CR C +  +   C EC  G  H+ H +++  +    +CDC
Sbjct: 668 INQDIFECRTCGLLESLCCCTEC-AGVCHKGHDWKLKRTSPTAYCDC 713


>gi|113420453 PREDICTED: similar to ubiquitin protein ligase E3
            component n-recognin 5 isoform 1 [Homo sapiens]
          Length = 2796

 Score = 34.3 bits (77), Expect = 1.1
 Identities = 12/47 (25%), Positives = 23/47 (48%), Gaps = 1/47 (2%)

Query: 105  VGEPTYSCRDCAVDPTCVLCMECFLGSIHRDHRYRMTTSGGGGFCDC 151
            + +  + CR C +  +   C EC  G  H+ H +++  +    +CDC
Sbjct: 1187 INQDIFECRTCGLLESLCCCTEC-AGVCHKGHDWKLKRTSPTAYCDC 1232


>gi|34850061 superiorcervical ganglia, neural specific 10 [Homo
            sapiens]
          Length = 179

 Score = 33.9 bits (76), Expect = 1.4
 Identities = 18/63 (28%), Positives = 31/63 (49%)

Query: 1007 PTSPVAETEGTIMEESSRDKDKAERKRKAEIARLRREKIMAQMSEMQRHFIDENKELFQQ 1066
            P SP++E   T+     +D    E ++K E A  RR+   AQ+ +      +  +E+ Q+
Sbjct: 60   PPSPISEAPRTLASPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQK 119

Query: 1067 TLE 1069
             LE
Sbjct: 120  ALE 122


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 33.9 bits (76), Expect = 1.4
 Identities = 38/187 (20%), Positives = 86/187 (45%), Gaps = 14/187 (7%)

Query: 930  MALQEEKQHLENVTEEHVVTFTFTQKISKPGEAPKNSPSILAMLETLQNAPYLEVHKDMI 989
            M  +E +Q LE + +E+        K  +     K++ ++  ++    N    +  +++ 
Sbjct: 1955 MLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREF-NTQLAQKEQELE 2013

Query: 990  RWILKTFNAVKKMRESSPTSPVAETEGTIMEESSRDKD-KAERKRKAEIARLRREKIMAQ 1048
              I +T N  +++      S   ET   + + + +D D K   KR  EI   R E++ A+
Sbjct: 2014 MTIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAK 2073

Query: 1049 MSEMQRHFIDENKELFQQTLELDASTSAVLDHSPVASDMTLTALGPAQTQVPEQRQFVTC 1108
            + ++Q   ++E ++ +QQ LE         + +P   ++T+  L   QTQ+ ++   ++ 
Sbjct: 2074 VRDLQTQ-LEELQKKYQQKLE--------QEENPGNDNVTIMEL---QTQLAQKTTLISD 2121

Query: 1109 ILCQEEQ 1115
               +E++
Sbjct: 2122 SKLKEQE 2128


>gi|42794779 myosin 18A isoform b [Homo sapiens]
          Length = 2039

 Score = 33.9 bits (76), Expect = 1.4
 Identities = 33/132 (25%), Positives = 62/132 (46%), Gaps = 17/132 (12%)

Query: 1019 MEESSRDKDKAERKRKAEIARLRREKIMAQMSEMQRHFIDENKELFQQTLELDASTSAV- 1077
            +EE   D ++  +K KA +A+  R+  +AQ++++Q    + NKE  +   +L A  S V 
Sbjct: 1748 LEEDQEDMNELMKKHKAAVAQASRD--LAQINDLQAQLEEANKEKQELQEKLQALQSQVE 1805

Query: 1078 -LDHSPVASDMTLTALGPAQTQVPEQRQFVTCILCQEEQEVKVESRAMVLAAFVQRST-- 1134
             L+ S V   +          Q  + R+  T +  +  Q  ++ES A  L   +++ T  
Sbjct: 1806 FLEQSMVDKSL-------VSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEE 1858

Query: 1135 ----VLSKNRSK 1142
                + ++NR K
Sbjct: 1859 RDQRIAAENREK 1870


>gi|28416946 myosin 18A isoform a [Homo sapiens]
          Length = 2054

 Score = 33.9 bits (76), Expect = 1.4
 Identities = 33/132 (25%), Positives = 62/132 (46%), Gaps = 17/132 (12%)

Query: 1019 MEESSRDKDKAERKRKAEIARLRREKIMAQMSEMQRHFIDENKELFQQTLELDASTSAV- 1077
            +EE   D ++  +K KA +A+  R+  +AQ++++Q    + NKE  +   +L A  S V 
Sbjct: 1748 LEEDQEDMNELMKKHKAAVAQASRD--LAQINDLQAQLEEANKEKQELQEKLQALQSQVE 1805

Query: 1078 -LDHSPVASDMTLTALGPAQTQVPEQRQFVTCILCQEEQEVKVESRAMVLAAFVQRST-- 1134
             L+ S V   +          Q  + R+  T +  +  Q  ++ES A  L   +++ T  
Sbjct: 1806 FLEQSMVDKSL-------VSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEE 1858

Query: 1135 ----VLSKNRSK 1142
                + ++NR K
Sbjct: 1859 RDQRIAAENREK 1870


>gi|109148542 alanyl-tRNA synthetase [Homo sapiens]
          Length = 968

 Score = 33.1 bits (74), Expect = 2.4
 Identities = 45/221 (20%), Positives = 86/221 (38%), Gaps = 35/221 (15%)

Query: 921  LQRVLHLIGMALQEEKQHLENVTEEHVVTFTFTQKISKPGEAPKNSPSILAMLETLQNAP 980
            L+   H     +  E+   + +     VT    QK  +  E+ K   S++      Q AP
Sbjct: 728  LRNSSHAGAFVIVTEEAIAKGIRRIVAVTGAEAQKALRKAESLKKCLSVMEAKVKAQTAP 787

Query: 981  YLEVHKDMIRWILKTFNAVKKMRESSPTSPVAETEGTIMEESSRDKDKAERKRKAEIARL 1040
              +V ++           +  + E+  T+ + + +    ++  R+  K+ +K   ++ R 
Sbjct: 788  NKDVQRE-----------IADLGEALATAVIPQWQ----KDELRETLKSLKKVMDDLDRA 832

Query: 1041 RREKIMAQMSEMQRHFIDENKELFQQTLELDASTSA---------VLDHSPVASDMTLTA 1091
             +  +  ++ E  + FID N       LE+++  SA            HSP  S M  T 
Sbjct: 833  SKADVQKRVLEKTKQFIDSNPNQPLVILEMESGASAKALNEALKLFKMHSPQTSAMLFT- 891

Query: 1092 LGPAQTQVPEQRQFVTCILCQEEQEVKVESRAMVLAAFVQR 1132
                   V  +   +TC LCQ  Q     +R +  + +VQ+
Sbjct: 892  -------VDNEAGKITC-LCQVPQ--NAANRGLKASEWVQQ 922


>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
          Length = 2039

 Score = 32.7 bits (73), Expect = 3.2
 Identities = 30/143 (20%), Positives = 61/143 (42%), Gaps = 9/143 (6%)

Query: 939  LENVTEEHVVTFTFTQKISKPGEAPKNSPSILAMLETLQNAPYLE-------VHKDMIRW 991
            ++ + E+  +    T+K  K GE  KN+ +I    +  ++   ++         K+    
Sbjct: 841  VDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLA 900

Query: 992  ILKTFNAVKKMRESSPTSPVAETEGTIMEESSRDKDKAERKRKAEIARLRREKIMAQMSE 1051
              K  + ++K  + S  S  +++E    +E  R+ DK E+ R  E   +   K + +  E
Sbjct: 901  ESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQE--E 958

Query: 1052 MQRHFIDENKELFQQTLELDAST 1074
             +   +D NK   ++ L L   T
Sbjct: 959  KKSSIVDGNKAQHEKPLSLKEKT 981


>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
          Length = 2062

 Score = 32.7 bits (73), Expect = 3.2
 Identities = 30/143 (20%), Positives = 61/143 (42%), Gaps = 9/143 (6%)

Query: 939  LENVTEEHVVTFTFTQKISKPGEAPKNSPSILAMLETLQNAPYLE-------VHKDMIRW 991
            ++ + E+  +    T+K  K GE  KN+ +I    +  ++   ++         K+    
Sbjct: 864  VDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLA 923

Query: 992  ILKTFNAVKKMRESSPTSPVAETEGTIMEESSRDKDKAERKRKAEIARLRREKIMAQMSE 1051
              K  + ++K  + S  S  +++E    +E  R+ DK E+ R  E   +   K + +  E
Sbjct: 924  ESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQE--E 981

Query: 1052 MQRHFIDENKELFQQTLELDAST 1074
             +   +D NK   ++ L L   T
Sbjct: 982  KKSSIVDGNKAQHEKPLSLKEKT 1004


>gi|4505257 moesin [Homo sapiens]
          Length = 577

 Score = 32.3 bits (72), Expect = 4.2
 Identities = 35/170 (20%), Positives = 67/170 (39%), Gaps = 9/170 (5%)

Query: 979  APYLEVHKDMIRWILKTFNAVKKMRESSPTSPVAETEGTIMEES-SRDKDKA---ERKRK 1034
            AP L ++K ++   +       + R+   T  V + +    EE   +  ++A     K+K
Sbjct: 271  APRLRINKRILALCMGNHELYMRRRKPD-TIEVQQMKAQAREEKHQKQMERAMLENEKKK 329

Query: 1035 AEIARLRREKIMAQMSEMQRHF--IDENKELFQQTLELDASTSAVLDHSPVASDMTLTAL 1092
             E+A   +EKI  +  E+      I+E  +  QQ LE     +  L+     +      L
Sbjct: 330  REMAEKEKEKIEREKEELMERLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKL 389

Query: 1093 GPAQTQVPEQRQFVTCILCQEEQEVKVESRAMVLAAFVQRSTVLSKNRSK 1142
               + +  E ++    +    +Q+   E  A+ +A    R + L   R K
Sbjct: 390  AKERQEAEEAKE--ALLQASRDQKKTQEQLALEMAELTARISQLEMARQK 437


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 32.3 bits (72), Expect = 4.2
 Identities = 34/151 (22%), Positives = 61/151 (40%), Gaps = 21/151 (13%)

Query: 932  LQEEKQHLENVTEEHVVTFTFT--QKISKPGEAPKNSPSILAMLETLQNAPYLEVHKDMI 989
            + EE+ + E   +E V TF     +K   PG   +      A+ ET Q A   E   + +
Sbjct: 76   MMEEQGYEEQQIQEKVATFRLMLLEKDVNPGGKEETPGQRPAVTETHQLAELNEKKNERL 135

Query: 990  RWIL---------KTFNAVKKMRESSPTSPVAETEGTIMEESS----------RDKDKAE 1030
            R             +F+  ++ RE+   +P      +++ ESS          + K K +
Sbjct: 136  RAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKD 195

Query: 1031 RKRKAEIARLRREKIMAQMSEMQRHFIDENK 1061
            R R++E +  RRE+  +   +  R   +  K
Sbjct: 196  RGRRSESSSPRRERKKSSKKKKHRSESESKK 226


>gi|32140182 keratin associated protein 10-10 [Homo sapiens]
          Length = 251

 Score = 32.3 bits (72), Expect = 4.2
 Identities = 21/52 (40%), Positives = 28/52 (53%), Gaps = 7/52 (13%)

Query: 1619 CPKSGGDK---SRAPTLCLVCGSLLCSQSYCCQTELEGEDVGAC-TAHTYSC 1666
            CP+S  +    + AP+L LVC  + C  S CCQT  E     AC + +T SC
Sbjct: 22   CPESCCEPCCCAPAPSLTLVCTPVSCVSSPCCQTACE---PSACQSGYTSSC 70


>gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens]
          Length = 1219

 Score = 32.3 bits (72), Expect = 4.2
 Identities = 35/158 (22%), Positives = 76/158 (48%), Gaps = 12/158 (7%)

Query: 1000 KKMRESSPTSPVAETEGTIMEESSRDKDKAERKRKAEIARLRREKIMAQMSEMQRHFIDE 1059
            +K  E   TS   E     +E+ S +K+ +ERK+K+   R + E+ + ++ +  +  +D+
Sbjct: 715  RKQLELKVTSLEEELTDLRVEKESLEKNLSERKKKSAQERSQAEEEIDEIRKSYQEELDK 774

Query: 1060 NKELFQQTLELDASTSAVLDHSPVASDMTLT-------ALGPAQTQVPEQRQFVTCILCQ 1112
             ++L ++T  +    +A    S V +++           L  A+ +  +Q Q V      
Sbjct: 775  LRQLLKKT-RVSTDQAAAEQLSLVQAELQTQWEAKCEHLLASAKDEHLQQYQEVCAQRDA 833

Query: 1113 EEQE-VKVESRAMVLAAFVQRSTVLSKNRSKFIQDPEK 1149
             +Q+ V+++ + + L A +   T L+K   + I++ EK
Sbjct: 834  YQQKLVQLQEKCLALQAQI---TALTKQNEQHIKELEK 868


>gi|30795240 aryl hydrocarbon receptor nuclear translocator isoform 2
            [Homo sapiens]
          Length = 328

 Score = 32.0 bits (71), Expect = 5.4
 Identities = 14/33 (42%), Positives = 23/33 (69%)

Query: 1020 EESSRDKDKAERKRKAEIARLRREKIMAQMSEM 1052
            E+SS DK++  R+  +EI R RR K+ A ++E+
Sbjct: 80   EQSSADKERLARENHSEIERRRRNKMTAYITEL 112


>gi|4502231 aryl hydrocarbon receptor nuclear translocator isoform 1
            [Homo sapiens]
          Length = 789

 Score = 32.0 bits (71), Expect = 5.4
 Identities = 14/33 (42%), Positives = 23/33 (69%)

Query: 1020 EESSRDKDKAERKRKAEIARLRREKIMAQMSEM 1052
            E+SS DK++  R+  +EI R RR K+ A ++E+
Sbjct: 80   EQSSADKERLARENHSEIERRRRNKMTAYITEL 112


>gi|4758128 doublecortin-like kinase 1 [Homo sapiens]
          Length = 729

 Score = 32.0 bits (71), Expect = 5.4
 Identities = 31/152 (20%), Positives = 60/152 (39%), Gaps = 16/152 (10%)

Query: 266 RDGRRSVRYGDFQYCEQAKSVIVRNTSRQTKPLKVQVMHSSIVAHQNFGLKLLSWLGSII 325
           +DG +S++ GDF         +       T       +   I+A   +GLK+  W   +I
Sbjct: 523 QDGSKSLKLGDFGLATIVDGPLYTVCGTPT------YVAPEIIAETGYGLKVDIWAAGVI 576

Query: 326 GYSDGLRRILCQVGLQEGPDGENSSLVDRLMLSD----SKLWKGARSVYHQLFMSSLLMD 381
            Y      +LC      G   +   L D++++      S  W        +L    LL+D
Sbjct: 577 TYI-----LLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVD 631

Query: 382 LKYKKLFAVRFAKNYQQLQRDFMEDDHERAVS 413
           +  ++  AV+  ++         E++H+ +V+
Sbjct: 632 VD-QRFSAVQVLEHPWVNDDGLPENEHQLSVA 662


>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
          Length = 1220

 Score = 31.6 bits (70), Expect = 7.1
 Identities = 28/137 (20%), Positives = 56/137 (40%), Gaps = 21/137 (15%)

Query: 1011 VAETEGTIMEESSRDKDKAERKRKAEIAR-LRREKIMAQMSEMQRHFIDENKELFQQTLE 1069
            +A+ E    E   R++ + ERKR+ E+ + L +++ + +  E +R    E +E  ++ LE
Sbjct: 383  LAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELE 442

Query: 1070 LDASTS--------------------AVLDHSPVASDMTLTALGPAQTQVPEQRQFVTCI 1109
                                       VL       +  L AL   + Q+  + Q + C 
Sbjct: 443  RQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCR 502

Query: 1110 LCQEEQEVKVESRAMVL 1126
            L  + QE++  +++  L
Sbjct: 503  LTTQRQEIESTNKSREL 519


>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
          Length = 1721

 Score = 31.6 bits (70), Expect = 7.1
 Identities = 28/137 (20%), Positives = 56/137 (40%), Gaps = 21/137 (15%)

Query: 1011 VAETEGTIMEESSRDKDKAERKRKAEIAR-LRREKIMAQMSEMQRHFIDENKELFQQTLE 1069
            +A+ E    E   R++ + ERKR+ E+ + L +++ + +  E +R    E +E  ++ LE
Sbjct: 383  LAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELE 442

Query: 1070 LDASTS--------------------AVLDHSPVASDMTLTALGPAQTQVPEQRQFVTCI 1109
                                       VL       +  L AL   + Q+  + Q + C 
Sbjct: 443  RQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCR 502

Query: 1110 LCQEEQEVKVESRAMVL 1126
            L  + QE++  +++  L
Sbjct: 503  LTTQRQEIESTNKSREL 519


>gi|31563524 myosin regulatory light chain 9 isoform b [Homo
           sapiens]
          Length = 118

 Score = 31.6 bits (70), Expect = 7.1
 Identities = 20/60 (33%), Positives = 27/60 (45%)

Query: 113 RDCAVDPTCVLCMECFLGSIHRDHRYRMTTSGGGGFCDCGDTEAWKEGPYCQKHELNTSE 172
           RD  +D   +  M   LG IH DH   + T+ G  F D    E ++E P  +K   N  E
Sbjct: 45  RDGFIDKEDLHDMLASLGFIHEDHLRELLTTMGDRFTDEEVDEMYREAPIDKKGNFNYVE 104


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.135    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 70,008,404
Number of Sequences: 37866
Number of extensions: 3264302
Number of successful extensions: 9823
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 32
Number of HSP's that attempted gapping in prelim test: 9743
Number of HSP's gapped (non-prelim): 102
length of query: 1755
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1639
effective length of database: 13,855,062
effective search space: 22708446618
effective search space used: 22708446618
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.