BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|27544941 myosin IF [Homo sapiens] (1098 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|27544941 myosin IF [Homo sapiens] 2223 0.0 gi|55956916 myosin IE [Homo sapiens] 1605 0.0 gi|124494247 myosin IC isoform b [Homo sapiens] 612 e-175 gi|124494238 myosin IC isoform a [Homo sapiens] 612 e-175 gi|124494240 myosin IC isoform c [Homo sapiens] 612 e-175 gi|194328685 myosin IB isoform 1 [Homo sapiens] 611 e-174 gi|44889481 myosin IB isoform 2 [Homo sapiens] 611 e-174 gi|240120050 myosin IB isoform 1 [Homo sapiens] 611 e-174 gi|254028267 myosin 1H [Homo sapiens] 596 e-170 gi|4885503 myosin IA [Homo sapiens] 571 e-162 gi|51100974 myosin ID [Homo sapiens] 539 e-153 gi|239582755 myosin IG [Homo sapiens] 507 e-143 gi|189083802 myosin VIIA isoform 2 [Homo sapiens] 481 e-135 gi|189083800 myosin VIIA isoform 3 [Homo sapiens] 481 e-135 gi|189083798 myosin VIIA isoform 1 [Homo sapiens] 481 e-135 gi|153945715 myosin VC [Homo sapiens] 473 e-133 gi|122937512 myosin VIIB [Homo sapiens] 473 e-133 gi|118402590 myosin XV [Homo sapiens] 463 e-130 gi|154354979 myosin X [Homo sapiens] 458 e-128 gi|122937345 myosin VB [Homo sapiens] 457 e-128 gi|215982794 myosin VA isoform 2 [Homo sapiens] 455 e-128 gi|215982791 myosin VA isoform 1 [Homo sapiens] 455 e-128 gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 433 e-121 gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 431 e-120 gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 428 e-119 gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 420 e-117 gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 420 e-117 gi|156104908 myosin heavy chain 6 [Homo sapiens] 419 e-117 gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 419 e-117 gi|92859701 myosin VI [Homo sapiens] 419 e-116 >gi|27544941 myosin IF [Homo sapiens] Length = 1098 Score = 2223 bits (5761), Expect = 0.0 Identities = 1098/1098 (100%), Positives = 1098/1098 (100%) Query: 1 MGSKERFHWQSHNVKQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPF 60 MGSKERFHWQSHNVKQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPF Sbjct: 1 MGSKERFHWQSHNVKQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPF 60 Query: 61 KQMPYFTDREIDLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAA 120 KQMPYFTDREIDLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAA Sbjct: 61 KQMPYFTDREIDLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAA 120 Query: 121 KYIMGYISKVSGGGEKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGG 180 KYIMGYISKVSGGGEKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGG Sbjct: 121 KYIMGYISKVSGGGEKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGG 180 Query: 181 EPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSD 240 EPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSD Sbjct: 181 EPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSD 240 Query: 241 TYQVDGTDDRSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESV 300 TYQVDGTDDRSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESV Sbjct: 241 TYQVDGTDDRSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESV 300 Query: 301 DLLAFPAYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYAR 360 DLLAFPAYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYAR Sbjct: 301 DLLAFPAYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYAR 360 Query: 361 LFDFLVEAINRAMQKPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLK 420 LFDFLVEAINRAMQKPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLK Sbjct: 361 LFDFLVEAINRAMQKPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLK 420 Query: 421 AEQEEYVQEGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLL 480 AEQEEYVQEGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLL Sbjct: 421 AEQEEYVQEGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLL 480 Query: 481 QKLQAAVGTHEHFNSWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQAFL 540 QKLQAAVGTHEHFNSWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQAFL Sbjct: 481 QKLQAAVGTHEHFNSWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQAFL 540 Query: 541 RMLFPEKLDGDKKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPRDWEENR 600 RMLFPEKLDGDKKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPRDWEENR Sbjct: 541 RMLFPEKLDGDKKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPRDWEENR 600 Query: 601 VKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWPRWRGDERQGVQHLLRAV 660 VKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWPRWRGDERQGVQHLLRAV Sbjct: 601 VKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWPRWRGDERQGVQHLLRAV 660 Query: 661 NMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQKAWRRHVAVRKYEEMREEA 720 NMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQKAWRRHVAVRKYEEMREEA Sbjct: 661 NMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQKAWRRHVAVRKYEEMREEA 720 Query: 721 SNILLNKKERRRNSINRNFVGDYLGLEERPELRQFLGKRERVDFADSVTKYDRRFKPIKR 780 SNILLNKKERRRNSINRNFVGDYLGLEERPELRQFLGKRERVDFADSVTKYDRRFKPIKR Sbjct: 721 SNILLNKKERRRNSINRNFVGDYLGLEERPELRQFLGKRERVDFADSVTKYDRRFKPIKR 780 Query: 781 DLILTPKCVYVIGREKVKKGPEKGQVCEVLKKKVDIQALRGVSLSTRQDDFFILQEDAAD 840 DLILTPKCVYVIGREKVKKGPEKGQVCEVLKKKVDIQALRGVSLSTRQDDFFILQEDAAD Sbjct: 781 DLILTPKCVYVIGREKVKKGPEKGQVCEVLKKKVDIQALRGVSLSTRQDDFFILQEDAAD 840 Query: 841 SFLESVFKTEFVSLLCKRFEEATRRPLPLTFSDTLQFRVKKEGWGGGGTRSVTFSRGFGD 900 SFLESVFKTEFVSLLCKRFEEATRRPLPLTFSDTLQFRVKKEGWGGGGTRSVTFSRGFGD Sbjct: 841 SFLESVFKTEFVSLLCKRFEEATRRPLPLTFSDTLQFRVKKEGWGGGGTRSVTFSRGFGD 900 Query: 901 LAVLKVGGRTLTVSVGDGLPKSSKPTRKGMAKGKPRRSSQAPTRAAPAPPRGMDRNGVPP 960 LAVLKVGGRTLTVSVGDGLPKSSKPTRKGMAKGKPRRSSQAPTRAAPAPPRGMDRNGVPP Sbjct: 901 LAVLKVGGRTLTVSVGDGLPKSSKPTRKGMAKGKPRRSSQAPTRAAPAPPRGMDRNGVPP 960 Query: 961 SARGGPLPLEIMSGGGTHRPPRGPPSTSLGASRRPRARPPSEHNTEFLNVPDQGMAGMQR 1020 SARGGPLPLEIMSGGGTHRPPRGPPSTSLGASRRPRARPPSEHNTEFLNVPDQGMAGMQR Sbjct: 961 SARGGPLPLEIMSGGGTHRPPRGPPSTSLGASRRPRARPPSEHNTEFLNVPDQGMAGMQR 1020 Query: 1021 KRSVGQRPVPGVGRPKPQPRTHGPRCRALYQYVGQDVDELSFNVNEVIEILMEDPSGWWK 1080 KRSVGQRPVPGVGRPKPQPRTHGPRCRALYQYVGQDVDELSFNVNEVIEILMEDPSGWWK Sbjct: 1021 KRSVGQRPVPGVGRPKPQPRTHGPRCRALYQYVGQDVDELSFNVNEVIEILMEDPSGWWK 1080 Query: 1081 GRLHGQEGLFPGNYVEKI 1098 GRLHGQEGLFPGNYVEKI Sbjct: 1081 GRLHGQEGLFPGNYVEKI 1098 >gi|55956916 myosin IE [Homo sapiens] Length = 1108 Score = 1605 bits (4157), Expect = 0.0 Identities = 796/1116 (71%), Positives = 933/1116 (83%), Gaps = 26/1116 (2%) Query: 1 MGSKE--RFHWQSHNVKQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVN 58 MGSK ++HWQSHNVK SGVDDMVLL +ITE++I NL+KR+MDDYIFTYIGSVLISVN Sbjct: 1 MGSKGVYQYHWQSHNVKHSGVDDMVLLSKITENSIVENLKKRYMDDYIFTYIGSVLISVN 60 Query: 59 PFKQMPYFTDREIDLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTV 118 PFKQMPYF ++EI++YQGAAQYENPPHIYAL DNMYRNM+ID ENQCVIISGESGAGKTV Sbjct: 61 PFKQMPYFGEKEIEMYQGAAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTV 120 Query: 119 AAKYIMGYISKVSGGGEKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSR 178 AAKYIM YIS+VSGGG KVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFS Sbjct: 121 AAKYIMSYISRVSGGGTKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSP 180 Query: 179 GGEPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQ 238 GGEPDGGKISNFLLEKSRVVM+N ER+FHI+YQL+EGAS EQ+ +LG+ + DYYYYL+ Sbjct: 181 GGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGASAEQKHSLGITSMDYYYYLSL 240 Query: 239 SDTYQVDGTDDRSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVE 298 S +Y+VD DDR +F ETL AM VIGI Q LVLQ+VAGILHLGNISF E GNYA VE Sbjct: 241 SGSYKVDDIDDRREFQETLHAMNVIGIFAEEQTLVLQIVAGILHLGNISFKEVGNYAAVE 300 Query: 299 SVDLLAFPAYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLY 358 S + LAFPAYLLGI+ RL+EKLTSR+MDS+WGG+SESI+VTLNVEQA YTRDALAK L+ Sbjct: 301 SEEFLAFPAYLLGINQDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALH 360 Query: 359 ARLFDFLVEAINRAMQKPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELT 418 AR+FDFLV++IN+AM+K EEY+IGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELT Sbjct: 361 ARVFDFLVDSINKAMEKDHEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELT 420 Query: 419 LKAEQEEYVQEGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQT 478 LKAEQEEYVQEGIRWTPI+YFNNK+VCDLIENK++PPGIMS+LDDVCATMHA G GADQT Sbjct: 421 LKAEQEEYVQEGIRWTPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQT 480 Query: 479 LLQKLQAAVGTHEHFNSWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQA 538 LLQKLQ +G+HEHFNSW+ GF+IHHYAGKVSYD+ GFCERNRDVLF DLIELMQ+SE Sbjct: 481 LLQKLQMQIGSHEHFNSWNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSELP 540 Query: 539 FLRMLFPEKLDGDKKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPRDWEE 598 F++ LFPE L DKKGRP+TAGSKIKKQANDLV+TLM+CTPHYIRCIKPNETK+PRDWEE Sbjct: 541 FIKSLFPENLQADKKGRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPRDWEE 600 Query: 599 NRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWPRWRGDERQGVQHLLR 658 +RVKHQVEYLGLKENIRVRRAG+AYRR F KFLQRYAILT TWP W+G+E+QGV HLL+ Sbjct: 601 SRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWPSWQGEEKQGVLHLLQ 660 Query: 659 AVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQKAWRRHVAVRKYEEMRE 718 +VNM+ DQ+Q+G +KVF+K PESLFLLEE+RERK+DG+AR IQK+WR+ VA +KY +MRE Sbjct: 661 SVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKSWRKFVARKKYVQMRE 720 Query: 719 EASNILLNKKERRRNSINRNFVGDYLGLEERPELRQFLGKRERVDFADSVTKYDRRFKPI 778 EAS++LLNKKERRRNSINRNF+GDY+G+EE PEL+QF+GKRE++DFAD+VTKYDRRFK + Sbjct: 721 EASDLLLNKKERRRNSINRNFIGDYIGMEEHPELQQFVGKREKIDFADTVTKYDRRFKGV 780 Query: 779 KRDLILTPKCVYVIGREKVKKGPEKGQVCEVLKKKVDIQALRGVSLSTRQDDFFILQEDA 838 KRDL+LTPKC+Y+IGREKVK+GP+KG V EVLK+K++I+ + VSLST QDD FIL E Sbjct: 781 KRDLLLTPKCLYLIGREKVKQGPDKGLVKEVLKRKIEIERILSVSLSTMQDDIFILHEQE 840 Query: 839 ADSFLESVFKTEFVSLLCKRFEEATRRPLPLTFSDTLQFRVKKEGWG---GGGTRSVTFS 895 DS LESVFKTEF+SLL KR+EE T++ LPL FS+TL+ ++KKE WG GG+R V F Sbjct: 841 YDSLLESVFKTEFLSLLAKRYEEKTQKQLPLKFSNTLELKLKKENWGPWSAGGSRQVQFH 900 Query: 896 RGFGDLAVLKVGGRTLTVSVGDGLPKSSKPTRKGMAK----GKPRRSSQAPTRAAPAPPR 951 +GFGDLAVLK + L VS+G GLPK+S+PTR+ + +++ P RAAP PP Sbjct: 901 QGFGDLAVLKPSNKVLQVSIGPGLPKNSRPTRRNTTQNTGYSSGTQNANYPVRAAPPPP- 959 Query: 952 GMDRNGVPPSARGGPLPLEIMSGGGTHRPPRGPPSTSLGASRRPRARPPSE-------HN 1004 G +NGV R +P G+ R + TS+ PR + S + Sbjct: 960 GYHQNGV---IRNQYVPYP--HAPGSQRSNQKSLYTSMARPPLPRQQSTSSDRVSQTPES 1014 Query: 1005 TEFLNVPDQGMAGMQRKRSVGQRPVPGVGRPKPQ--PRTHGPRCRALYQYVGQDVDELSF 1062 +FL VPDQG AG++R+ + RP P GRPKPQ P+ P+C+ALY Y QD DELSF Sbjct: 1015 LDFLKVPDQGAAGVRRQTT--SRPPPAGGRPKPQPKPKPQVPQCKALYAYDAQDTDELSF 1072 Query: 1063 NVNEVIEILMEDPSGWWKGRLHGQEGLFPGNYVEKI 1098 N N++I+I+ EDPSGWW GRL G++GLFP NYV KI Sbjct: 1073 NANDIIDIIKEDPSGWWTGRLRGKQGLFPNNYVTKI 1108 >gi|124494247 myosin IC isoform b [Homo sapiens] Length = 1044 Score = 612 bits (1579), Expect = e-175 Identities = 334/726 (46%), Positives = 460/726 (63%), Gaps = 34/726 (4%) Query: 18 GVDDMVLLPQIT-EDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLYQG 76 GV D VLL T E A NLR+RF ++ I+TYIG VL+SVNP++ + ++ + ++ Y+G Sbjct: 28 GVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRG 87 Query: 77 AAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGGEK 136 + YE PPH++A+ D +YR + + +Q V+ISGESGAGKT A K ++ + ++ E+ Sbjct: 88 VSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPER 147 Query: 137 VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSR 196 V+D +LQSNP+LEAFGNAKT+RN+NSSRFGKY ++QF G P GG I ++LLEKSR Sbjct: 148 GGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSR 207 Query: 197 VVMQNENERNFHIYYQLLEGASQEQRQNLGL-MTPDYYYYLNQSDTYQVDGTDDRSDFGE 255 VV QN ERNFHI+YQLLEG +E + LGL P Y YL + +V +D+SD+ Sbjct: 208 VVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWKV 267 Query: 256 TLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFC--EDGNYARVESVDLLAFPAYLLGID 313 A+ VI + +L +VA +LHLGNI F E+ N A+V + + L + LL ++ Sbjct: 268 VRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESN-AQVTTENQLKYLTRLLSVE 326 Query: 314 SGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDFLVEAINRAM 373 L+E LT RK+ + + E + LN+EQAAY RDALAK +Y+R F +LV INR++ Sbjct: 327 GSTLREALTHRKIIA----KGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSL 382 Query: 374 QKPQEEYS-------IGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEY 426 E +G+LDIYGFE+FQ N FEQFCIN+ NEKLQQ+FIELTLK+EQEEY Sbjct: 383 ASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEY 442 Query: 427 VQEGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQKLQAA 486 EGI W P+QYFNNK++CDL+E K GI+S+LD+ C G D T L+KL+ Sbjct: 443 EAEGIAWEPVQYFNNKIICDLVEEKFK--GIISILDEECL---RPGEATDLTFLEKLEDT 497 Query: 487 VGTHEHF-----------NSWSAG-FVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQT 534 V H HF S G F + HYAG+V+Y V+GF ++N D+LF +L E M + Sbjct: 498 VKHHPHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCS 557 Query: 535 SEQAFLRMLFPEKLDGDKKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPR 594 S+ + F DKK RP T ++ K LV L P Y+RCIKPN+ K+P Sbjct: 558 SKNPIMSQCFDRSELSDKK-RPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPG 616 Query: 595 DWEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWPRWRGDERQGVQ 654 ++E ++HQV+YLGL EN+RVRRAGFAYRR++ FLQRY L PETWP W G + GV Sbjct: 617 RFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVA 676 Query: 655 HLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQKAWRRHVAVRKYE 714 L+R + +P++Y+MG TK+F++ P++LF E+ E + A IQ AWR +K+ Sbjct: 677 VLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFL 736 Query: 715 EMREEA 720 ++ A Sbjct: 737 RVKRSA 742 Score = 68.2 bits (165), Expect = 4e-11 Identities = 46/148 (31%), Positives = 73/148 (49%), Gaps = 22/148 (14%) Query: 696 FARTIQKAWRRHVAVRKYEEMREEASNILLNKKERRRNSINRNFVGDYLGLEE-RPELRQ 754 + R+I W++ + + + AS I KK+ S+ R F+ LG +E P + Q Sbjct: 840 YCRSISPEWKQQL------QQKAVASEIFKGKKDNYPQSVPRLFISTRLGTDEISPRVLQ 893 Query: 755 FLGKRERVDFADSVTKYDRR-FKPIKRDLILTPKCVYVIGREKVKKGPEKGQVCEVLKKK 813 LG E + +A V KYDR+ +KP R L+LTP V ++ KVK+ + Sbjct: 894 ALGS-EPIQYAVPVVKYDRKGYKPRSRQLLLTPNAVVIVEDAKVKQ-------------R 939 Query: 814 VDIQALRGVSLSTRQDDFFILQEDAADS 841 +D L G+S+S+ D F+L AD+ Sbjct: 940 IDYANLTGISVSSLSDSLFVLHVQRADN 967 >gi|124494238 myosin IC isoform a [Homo sapiens] Length = 1063 Score = 612 bits (1579), Expect = e-175 Identities = 334/726 (46%), Positives = 460/726 (63%), Gaps = 34/726 (4%) Query: 18 GVDDMVLLPQIT-EDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLYQG 76 GV D VLL T E A NLR+RF ++ I+TYIG VL+SVNP++ + ++ + ++ Y+G Sbjct: 47 GVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRG 106 Query: 77 AAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGGEK 136 + YE PPH++A+ D +YR + + +Q V+ISGESGAGKT A K ++ + ++ E+ Sbjct: 107 VSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPER 166 Query: 137 VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSR 196 V+D +LQSNP+LEAFGNAKT+RN+NSSRFGKY ++QF G P GG I ++LLEKSR Sbjct: 167 GGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSR 226 Query: 197 VVMQNENERNFHIYYQLLEGASQEQRQNLGL-MTPDYYYYLNQSDTYQVDGTDDRSDFGE 255 VV QN ERNFHI+YQLLEG +E + LGL P Y YL + +V +D+SD+ Sbjct: 227 VVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWKV 286 Query: 256 TLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFC--EDGNYARVESVDLLAFPAYLLGID 313 A+ VI + +L +VA +LHLGNI F E+ N A+V + + L + LL ++ Sbjct: 287 VRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESN-AQVTTENQLKYLTRLLSVE 345 Query: 314 SGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDFLVEAINRAM 373 L+E LT RK+ + + E + LN+EQAAY RDALAK +Y+R F +LV INR++ Sbjct: 346 GSTLREALTHRKIIA----KGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSL 401 Query: 374 QKPQEEYS-------IGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEY 426 E +G+LDIYGFE+FQ N FEQFCIN+ NEKLQQ+FIELTLK+EQEEY Sbjct: 402 ASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEY 461 Query: 427 VQEGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQKLQAA 486 EGI W P+QYFNNK++CDL+E K GI+S+LD+ C G D T L+KL+ Sbjct: 462 EAEGIAWEPVQYFNNKIICDLVEEKFK--GIISILDEECL---RPGEATDLTFLEKLEDT 516 Query: 487 VGTHEHF-----------NSWSAG-FVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQT 534 V H HF S G F + HYAG+V+Y V+GF ++N D+LF +L E M + Sbjct: 517 VKHHPHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCS 576 Query: 535 SEQAFLRMLFPEKLDGDKKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPR 594 S+ + F DKK RP T ++ K LV L P Y+RCIKPN+ K+P Sbjct: 577 SKNPIMSQCFDRSELSDKK-RPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPG 635 Query: 595 DWEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWPRWRGDERQGVQ 654 ++E ++HQV+YLGL EN+RVRRAGFAYRR++ FLQRY L PETWP W G + GV Sbjct: 636 RFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVA 695 Query: 655 HLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQKAWRRHVAVRKYE 714 L+R + +P++Y+MG TK+F++ P++LF E+ E + A IQ AWR +K+ Sbjct: 696 VLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFL 755 Query: 715 EMREEA 720 ++ A Sbjct: 756 RVKRSA 761 Score = 68.2 bits (165), Expect = 4e-11 Identities = 46/148 (31%), Positives = 73/148 (49%), Gaps = 22/148 (14%) Query: 696 FARTIQKAWRRHVAVRKYEEMREEASNILLNKKERRRNSINRNFVGDYLGLEE-RPELRQ 754 + R+I W++ + + + AS I KK+ S+ R F+ LG +E P + Q Sbjct: 859 YCRSISPEWKQQL------QQKAVASEIFKGKKDNYPQSVPRLFISTRLGTDEISPRVLQ 912 Query: 755 FLGKRERVDFADSVTKYDRR-FKPIKRDLILTPKCVYVIGREKVKKGPEKGQVCEVLKKK 813 LG E + +A V KYDR+ +KP R L+LTP V ++ KVK+ + Sbjct: 913 ALGS-EPIQYAVPVVKYDRKGYKPRSRQLLLTPNAVVIVEDAKVKQ-------------R 958 Query: 814 VDIQALRGVSLSTRQDDFFILQEDAADS 841 +D L G+S+S+ D F+L AD+ Sbjct: 959 IDYANLTGISVSSLSDSLFVLHVQRADN 986 >gi|124494240 myosin IC isoform c [Homo sapiens] Length = 1028 Score = 612 bits (1579), Expect = e-175 Identities = 334/726 (46%), Positives = 460/726 (63%), Gaps = 34/726 (4%) Query: 18 GVDDMVLLPQIT-EDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLYQG 76 GV D VLL T E A NLR+RF ++ I+TYIG VL+SVNP++ + ++ + ++ Y+G Sbjct: 12 GVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRG 71 Query: 77 AAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGGEK 136 + YE PPH++A+ D +YR + + +Q V+ISGESGAGKT A K ++ + ++ E+ Sbjct: 72 VSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPER 131 Query: 137 VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSR 196 V+D +LQSNP+LEAFGNAKT+RN+NSSRFGKY ++QF G P GG I ++LLEKSR Sbjct: 132 GGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSR 191 Query: 197 VVMQNENERNFHIYYQLLEGASQEQRQNLGL-MTPDYYYYLNQSDTYQVDGTDDRSDFGE 255 VV QN ERNFHI+YQLLEG +E + LGL P Y YL + +V +D+SD+ Sbjct: 192 VVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWKV 251 Query: 256 TLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFC--EDGNYARVESVDLLAFPAYLLGID 313 A+ VI + +L +VA +LHLGNI F E+ N A+V + + L + LL ++ Sbjct: 252 VRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESN-AQVTTENQLKYLTRLLSVE 310 Query: 314 SGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDFLVEAINRAM 373 L+E LT RK+ + + E + LN+EQAAY RDALAK +Y+R F +LV INR++ Sbjct: 311 GSTLREALTHRKIIA----KGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSL 366 Query: 374 QKPQEEYS-------IGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEY 426 E +G+LDIYGFE+FQ N FEQFCIN+ NEKLQQ+FIELTLK+EQEEY Sbjct: 367 ASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEY 426 Query: 427 VQEGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQKLQAA 486 EGI W P+QYFNNK++CDL+E K GI+S+LD+ C G D T L+KL+ Sbjct: 427 EAEGIAWEPVQYFNNKIICDLVEEKFK--GIISILDEECL---RPGEATDLTFLEKLEDT 481 Query: 487 VGTHEHF-----------NSWSAG-FVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQT 534 V H HF S G F + HYAG+V+Y V+GF ++N D+LF +L E M + Sbjct: 482 VKHHPHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCS 541 Query: 535 SEQAFLRMLFPEKLDGDKKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPR 594 S+ + F DKK RP T ++ K LV L P Y+RCIKPN+ K+P Sbjct: 542 SKNPIMSQCFDRSELSDKK-RPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPG 600 Query: 595 DWEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWPRWRGDERQGVQ 654 ++E ++HQV+YLGL EN+RVRRAGFAYRR++ FLQRY L PETWP W G + GV Sbjct: 601 RFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVA 660 Query: 655 HLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQKAWRRHVAVRKYE 714 L+R + +P++Y+MG TK+F++ P++LF E+ E + A IQ AWR +K+ Sbjct: 661 VLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFL 720 Query: 715 EMREEA 720 ++ A Sbjct: 721 RVKRSA 726 Score = 68.2 bits (165), Expect = 4e-11 Identities = 46/148 (31%), Positives = 73/148 (49%), Gaps = 22/148 (14%) Query: 696 FARTIQKAWRRHVAVRKYEEMREEASNILLNKKERRRNSINRNFVGDYLGLEE-RPELRQ 754 + R+I W++ + + + AS I KK+ S+ R F+ LG +E P + Q Sbjct: 824 YCRSISPEWKQQL------QQKAVASEIFKGKKDNYPQSVPRLFISTRLGTDEISPRVLQ 877 Query: 755 FLGKRERVDFADSVTKYDRR-FKPIKRDLILTPKCVYVIGREKVKKGPEKGQVCEVLKKK 813 LG E + +A V KYDR+ +KP R L+LTP V ++ KVK+ + Sbjct: 878 ALGS-EPIQYAVPVVKYDRKGYKPRSRQLLLTPNAVVIVEDAKVKQ-------------R 923 Query: 814 VDIQALRGVSLSTRQDDFFILQEDAADS 841 +D L G+S+S+ D F+L AD+ Sbjct: 924 IDYANLTGISVSSLSDSLFVLHVQRADN 951 >gi|194328685 myosin IB isoform 1 [Homo sapiens] Length = 1136 Score = 611 bits (1575), Expect = e-174 Identities = 325/710 (45%), Positives = 451/710 (63%), Gaps = 31/710 (4%) Query: 18 GVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLYQGA 77 GV DMVLL + E+ NL+KRF I+TYIGSV+ISVNP++ +P ++ +++ Y+ Sbjct: 16 GVGDMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYRNR 75 Query: 78 AQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGGEKV 137 YE PHI+AL+D YR++ ++QC++I+GESGAGKT A+K +M Y++ V G G +V Sbjct: 76 NFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEV 135 Query: 138 QHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSRV 197 VK+ +LQSNP+LEAFGNAKTVRN+NSSRFGKY +I+F G+P GG ISN+LLEKSRV Sbjct: 136 NQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRV 195 Query: 198 VMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSDTYQVDGTDDRSDFGETL 257 V Q ERNFH++YQLL GAS+E L L Y D+ +V+G DD ++F Sbjct: 196 VKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDSAKVNGVDDAANFRTVR 255 Query: 258 SAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDG-----NYARVESVDLLAFPAYLLGI 312 +AMQ++G + VL +VA +L LGNI F + + ++++ + L L GI Sbjct: 256 NAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELTGI 315 Query: 313 DSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDFLVEAINRA 372 D L+ + R +++ + E ++ TLNV QA Y RDALAK LY+RLF +LV IN + Sbjct: 316 DQSVLERAFSFRTVEA----KQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINES 371 Query: 373 M--QKPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEG 430 + Q + +GVLDIYGFEIF+ N FEQF IN+ NEKLQQIFIELTLK EQEEY++E Sbjct: 372 IKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIRED 431 Query: 431 IRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQKLQAAVGTH 490 I WT I YFNN ++CDLIEN + GI+++LD+ C G D+T L+KL TH Sbjct: 432 IEWTHIDYFNNAIICDLIENNTN--GILAMLDEECL---RPGTVTDETFLEKLNQVCATH 486 Query: 491 EHFNSWSAG--------------FVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSE 536 +HF S + F I HYAGKV Y V GF ++N D+L+ DL + M + Sbjct: 487 QHFESRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKAS 546 Query: 537 QAFLRMLFPEKLDGD-KKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPRD 595 A ++ LFPE RP TAGS+ K L+ L P+YIRCIKPN+ K Sbjct: 547 HALIKSLFPEGNPAKINLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHI 606 Query: 596 WEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWPRWRGDERQGVQH 655 + E V HQ+ YLGL EN+RVRRAG+A+R+ + L+RY +L +TWP W+G R GV+ Sbjct: 607 FNEALVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEV 666 Query: 656 LLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQKAWR 705 L + + ++Y G +K+F++NP +LF LE++R+++ + A IQK +R Sbjct: 667 LFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYR 716 Score = 39.7 bits (91), Expect = 0.016 Identities = 47/180 (26%), Positives = 82/180 (45%), Gaps = 23/180 (12%) Query: 713 YEEMREEASNILLNKKERRRNSINRNFVGDYLGLEERPELRQFLGK-RERVDFADSVTKY 771 YEE + EAS + +KK +S+ + F G YL + + P+ ++ E++ A+ V K Sbjct: 938 YEE-KLEASELFKDKKALYPSSVGQPFQGAYLEINKNPKYKKLKDAIEEKIIIAEVVNKI 996 Query: 772 DR-RFKPIKRDLILTPKCVYVIGREKVKKGPEKGQVCEVLKKKVDIQALRGVSLSTRQDD 830 +R K R +LT + + + + GQ+ K +V + + VS+S++ D Sbjct: 997 NRANGKSTSRIFLLTNNNLLLADQ-------KSGQI----KSEVPLVDVTKVSMSSQNDG 1045 Query: 831 FFILQ----EDAA---DSFLESVFKTEFVSLLCKRFEEATRRPLPLTFSD--TLQFRVKK 881 FF + +AA D S E + L + T++ L + SD +QFR K Sbjct: 1046 FFAVHLKEGSEAASKGDFLFSSDHLIEMATKLYRTTLSQTKQKLNIEISDEFLVQFRQDK 1105 >gi|44889481 myosin IB isoform 2 [Homo sapiens] Length = 1078 Score = 611 bits (1575), Expect = e-174 Identities = 325/710 (45%), Positives = 451/710 (63%), Gaps = 31/710 (4%) Query: 18 GVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLYQGA 77 GV DMVLL + E+ NL+KRF I+TYIGSV+ISVNP++ +P ++ +++ Y+ Sbjct: 16 GVGDMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYRNR 75 Query: 78 AQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGGEKV 137 YE PHI+AL+D YR++ ++QC++I+GESGAGKT A+K +M Y++ V G G +V Sbjct: 76 NFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEV 135 Query: 138 QHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSRV 197 VK+ +LQSNP+LEAFGNAKTVRN+NSSRFGKY +I+F G+P GG ISN+LLEKSRV Sbjct: 136 NQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRV 195 Query: 198 VMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSDTYQVDGTDDRSDFGETL 257 V Q ERNFH++YQLL GAS+E L L Y D+ +V+G DD ++F Sbjct: 196 VKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDSAKVNGVDDAANFRTVR 255 Query: 258 SAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDG-----NYARVESVDLLAFPAYLLGI 312 +AMQ++G + VL +VA +L LGNI F + + ++++ + L L GI Sbjct: 256 NAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELTGI 315 Query: 313 DSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDFLVEAINRA 372 D L+ + R +++ + E ++ TLNV QA Y RDALAK LY+RLF +LV IN + Sbjct: 316 DQSVLERAFSFRTVEA----KQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINES 371 Query: 373 M--QKPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEG 430 + Q + +GVLDIYGFEIF+ N FEQF IN+ NEKLQQIFIELTLK EQEEY++E Sbjct: 372 IKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIRED 431 Query: 431 IRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQKLQAAVGTH 490 I WT I YFNN ++CDLIEN + GI+++LD+ C G D+T L+KL TH Sbjct: 432 IEWTHIDYFNNAIICDLIENNTN--GILAMLDEECL---RPGTVTDETFLEKLNQVCATH 486 Query: 491 EHFNSWSAG--------------FVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSE 536 +HF S + F I HYAGKV Y V GF ++N D+L+ DL + M + Sbjct: 487 QHFESRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKAS 546 Query: 537 QAFLRMLFPEKLDGD-KKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPRD 595 A ++ LFPE RP TAGS+ K L+ L P+YIRCIKPN+ K Sbjct: 547 HALIKSLFPEGNPAKINLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHI 606 Query: 596 WEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWPRWRGDERQGVQH 655 + E V HQ+ YLGL EN+RVRRAG+A+R+ + L+RY +L +TWP W+G R GV+ Sbjct: 607 FNEALVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEV 666 Query: 656 LLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQKAWR 705 L + + ++Y G +K+F++NP +LF LE++R+++ + A IQK +R Sbjct: 667 LFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYR 716 Score = 39.7 bits (91), Expect = 0.016 Identities = 47/180 (26%), Positives = 82/180 (45%), Gaps = 23/180 (12%) Query: 713 YEEMREEASNILLNKKERRRNSINRNFVGDYLGLEERPELRQFLGK-RERVDFADSVTKY 771 YEE + EAS + +KK +S+ + F G YL + + P+ ++ E++ A+ V K Sbjct: 880 YEE-KLEASELFKDKKALYPSSVGQPFQGAYLEINKNPKYKKLKDAIEEKIIIAEVVNKI 938 Query: 772 DR-RFKPIKRDLILTPKCVYVIGREKVKKGPEKGQVCEVLKKKVDIQALRGVSLSTRQDD 830 +R K R +LT + + + + GQ+ K +V + + VS+S++ D Sbjct: 939 NRANGKSTSRIFLLTNNNLLLADQ-------KSGQI----KSEVPLVDVTKVSMSSQNDG 987 Query: 831 FFILQ----EDAA---DSFLESVFKTEFVSLLCKRFEEATRRPLPLTFSD--TLQFRVKK 881 FF + +AA D S E + L + T++ L + SD +QFR K Sbjct: 988 FFAVHLKEGSEAASKGDFLFSSDHLIEMATKLYRTTLSQTKQKLNIEISDEFLVQFRQDK 1047 >gi|240120050 myosin IB isoform 1 [Homo sapiens] Length = 1136 Score = 611 bits (1575), Expect = e-174 Identities = 325/710 (45%), Positives = 451/710 (63%), Gaps = 31/710 (4%) Query: 18 GVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLYQGA 77 GV DMVLL + E+ NL+KRF I+TYIGSV+ISVNP++ +P ++ +++ Y+ Sbjct: 16 GVGDMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYRNR 75 Query: 78 AQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGGEKV 137 YE PHI+AL+D YR++ ++QC++I+GESGAGKT A+K +M Y++ V G G +V Sbjct: 76 NFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEV 135 Query: 138 QHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSRV 197 VK+ +LQSNP+LEAFGNAKTVRN+NSSRFGKY +I+F G+P GG ISN+LLEKSRV Sbjct: 136 NQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRV 195 Query: 198 VMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSDTYQVDGTDDRSDFGETL 257 V Q ERNFH++YQLL GAS+E L L Y D+ +V+G DD ++F Sbjct: 196 VKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDSAKVNGVDDAANFRTVR 255 Query: 258 SAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDG-----NYARVESVDLLAFPAYLLGI 312 +AMQ++G + VL +VA +L LGNI F + + ++++ + L L GI Sbjct: 256 NAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELTGI 315 Query: 313 DSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDFLVEAINRA 372 D L+ + R +++ + E ++ TLNV QA Y RDALAK LY+RLF +LV IN + Sbjct: 316 DQSVLERAFSFRTVEA----KQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINES 371 Query: 373 M--QKPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEG 430 + Q + +GVLDIYGFEIF+ N FEQF IN+ NEKLQQIFIELTLK EQEEY++E Sbjct: 372 IKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIRED 431 Query: 431 IRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQKLQAAVGTH 490 I WT I YFNN ++CDLIEN + GI+++LD+ C G D+T L+KL TH Sbjct: 432 IEWTHIDYFNNAIICDLIENNTN--GILAMLDEECL---RPGTVTDETFLEKLNQVCATH 486 Query: 491 EHFNSWSAG--------------FVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSE 536 +HF S + F I HYAGKV Y V GF ++N D+L+ DL + M + Sbjct: 487 QHFESRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKAS 546 Query: 537 QAFLRMLFPEKLDGD-KKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPRD 595 A ++ LFPE RP TAGS+ K L+ L P+YIRCIKPN+ K Sbjct: 547 HALIKSLFPEGNPAKINLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHI 606 Query: 596 WEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWPRWRGDERQGVQH 655 + E V HQ+ YLGL EN+RVRRAG+A+R+ + L+RY +L +TWP W+G R GV+ Sbjct: 607 FNEALVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEV 666 Query: 656 LLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQKAWR 705 L + + ++Y G +K+F++NP +LF LE++R+++ + A IQK +R Sbjct: 667 LFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYR 716 Score = 39.7 bits (91), Expect = 0.016 Identities = 47/180 (26%), Positives = 82/180 (45%), Gaps = 23/180 (12%) Query: 713 YEEMREEASNILLNKKERRRNSINRNFVGDYLGLEERPELRQFLGK-RERVDFADSVTKY 771 YEE + EAS + +KK +S+ + F G YL + + P+ ++ E++ A+ V K Sbjct: 938 YEE-KLEASELFKDKKALYPSSVGQPFQGAYLEINKNPKYKKLKDAIEEKIIIAEVVNKI 996 Query: 772 DR-RFKPIKRDLILTPKCVYVIGREKVKKGPEKGQVCEVLKKKVDIQALRGVSLSTRQDD 830 +R K R +LT + + + + GQ+ K +V + + VS+S++ D Sbjct: 997 NRANGKSTSRIFLLTNNNLLLADQ-------KSGQI----KSEVPLVDVTKVSMSSQNDG 1045 Query: 831 FFILQ----EDAA---DSFLESVFKTEFVSLLCKRFEEATRRPLPLTFSD--TLQFRVKK 881 FF + +AA D S E + L + T++ L + SD +QFR K Sbjct: 1046 FFAVHLKEGSEAASKGDFLFSSDHLIEMATKLYRTTLSQTKQKLNIEISDEFLVQFRQDK 1105 >gi|254028267 myosin 1H [Homo sapiens] Length = 1022 Score = 596 bits (1537), Expect = e-170 Identities = 317/721 (43%), Positives = 452/721 (62%), Gaps = 29/721 (4%) Query: 18 GVDDMVLLPQIT-EDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLYQG 76 GV D VLL T E A NLRKRF ++ I+TYIG++L+SVNP++++ +T +++LYQG Sbjct: 12 GVQDFVLLDAYTSESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGIYTVSQMELYQG 71 Query: 77 AAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGGEK 136 +E PPH+YA+ DN YR M + N ++ISGESGAGKT A+K I+ Y + + Sbjct: 72 VNFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEASKKILEYFAVTCPMTQS 131 Query: 137 VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSR 196 +Q +D +L SNP+LEAFGNA+T+RN+NSSRFGKY +IQF G P GG I ++L+EKSR Sbjct: 132 LQIARDRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGGHIISYLIEKSR 191 Query: 197 VVMQNENERNFHIYYQLLEGASQEQRQNLGL-MTPDYYYYLNQSDTYQVDGTDDRSDFGE 255 VV QNE ERNFHI+YQLL G +E+ LGL P Y YL+Q + D++D+ Sbjct: 192 VVYQNEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGHCAKESSISDKNDWKT 251 Query: 256 TLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDG-NYARVESVDLLAFPAYLLGIDS 314 +A VI + + + ++A +LHLGNI F ED A + + + A LLG+ Sbjct: 252 VSNAFSVIDFTEADLENLFGIIASVLHLGNIGFEEDDQGCATIPDTHEIKWIAKLLGVHP 311 Query: 315 GRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDFLVEAINRAMQ 374 L E LT RK+++ ++E + L +E + Y RDA+AK +Y R F +LV IN ++ Sbjct: 312 SVLLEALTHRKIEA----KTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVNKINSSLV 367 Query: 375 KPQ--EEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIR 432 + IG+LDIYGFE+F KNGFEQFCIN+ NEKLQQ+ IE TLKAEQ EY EGI Sbjct: 368 NKDFTRKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAEYEMEGIE 427 Query: 433 WTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQKLQAAVGTHEH 492 W PI+YFNNK++CDL+E + GI+S+LD+ C G D + L+KL+ VG H H Sbjct: 428 WEPIKYFNNKIICDLVEER--HKGIISILDEECI---RPGPATDLSFLEKLEEKVGKHAH 482 Query: 493 FNS-------------WSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQAF 539 F + W F + HYAG+V+Y GF E+N D+L+ L E++ S+ Sbjct: 483 FETRKLAGPKGRKRIGWME-FRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCKSKNII 541 Query: 540 LRMLFPEKLDGDKKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPRDWEEN 599 LR F + + + RP T G++ K + L+ TL+ P YIRCIKPN+ K P +++ Sbjct: 542 LRECF-LLAELENRRRPPTVGTQFKNSLSSLLETLISKEPSYIRCIKPNDRKEPSKFDDF 600 Query: 600 RVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWPRWRGDERQGVQHLLRA 659 ++HQ++YLGL E++RVRRAGFAYRR++ FLQRY L P+TWP W G +GV+ L++ Sbjct: 601 LIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHGPPAEGVERLIKY 660 Query: 660 VNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQKAWRRHVAVRKYEEMREE 719 + +P++Y++G TK+F++ P +LF E+ E IQ ++R + R+Y + R+ Sbjct: 661 IGYKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVARIQATYKRCLGRREYVKKRQA 720 Query: 720 A 720 A Sbjct: 721 A 721 Score = 55.1 bits (131), Expect = 4e-07 Identities = 43/145 (29%), Positives = 68/145 (46%), Gaps = 17/145 (11%) Query: 700 IQKAWRRHVAVRK-YEEMREEASNILLNKKERRRNSINRNFVGDYLGLEE-RPELRQFLG 757 +QK R A RK + + S I +K+ S+N+ FV + + P++ Q + Sbjct: 816 VQKYCRGITAERKAMMQQKVVTSEIFRGRKDGYTESLNQPFVNSRIDEGDINPKVLQLIS 875 Query: 758 KRERVDFADSVTKYDRR-FKPIKRDLILTPKCVYVIGREKVKKGPEKGQVCEVLKKKVDI 816 E++ + V KYDR+ FK +R LILT K YV+ K+K+ K++ Sbjct: 876 -HEKIQYGVPVIKYDRKGFKARQRQLILTQKAAYVVELAKIKQ-------------KIEY 921 Query: 817 QALRGVSLSTRQDDFFILQEDAADS 841 AL+GVS S D ++ DS Sbjct: 922 SALKGVSTSNLSDGILVIHVSPEDS 946 >gi|4885503 myosin IA [Homo sapiens] Length = 1043 Score = 571 bits (1472), Expect = e-162 Identities = 318/735 (43%), Positives = 462/735 (62%), Gaps = 41/735 (5%) Query: 18 GVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLYQGA 77 GV+D+VLL + E+++ NL+ R+ + I+TYIG+V+ISVNP++Q+P + I YQ Sbjct: 9 GVEDLVLLEPLVEESLLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPEFIAKYQDY 68 Query: 78 AQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGGEKV 137 YE PHIYAL + Y+++ +QC++I+GESG+GKT A+K +M Y++ V G GE+V Sbjct: 69 TFYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVCGKGEQV 128 Query: 138 QHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSRV 197 VK+ +LQSNP+LEAFGNAKT+RNNNSSRFGKY +I+F G P GG I+N+LLEKSR+ Sbjct: 129 NSVKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITNYLLEKSRL 188 Query: 198 VMQNENERNFHIYYQLLEGASQEQRQNLGL-MTPDYYYYLNQSDTYQVDGTDDRSDFGET 256 V Q + ERNFHI+YQLL GA ++ + L L Y YLN + +VDG DD S F Sbjct: 189 VKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYLNH-EVSRVDGMDDASSFRAV 247 Query: 257 LSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESVDL-----LAFPAYLLG 311 SAM VIG + VL++ + +L LGN+ ++ + + + + + ++G Sbjct: 248 QSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASGIRDGRGVREIGEMVG 307 Query: 312 IDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDFLVEAINR 371 ++S ++ L SR M++ E + LNV QA Y RDALAK +Y+RLFD++V IN Sbjct: 308 LNSEEVERALCSRTMET----AKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVNRINE 363 Query: 372 AMQK--PQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQE 429 +++ +++ +GVLDIYGFEI + N FEQF IN+ NEKLQQ+FIE+TLK EQEEY +E Sbjct: 364 SIKVGIGEKKKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEEQEEYKRE 423 Query: 430 GIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQKLQAAVGT 489 GI WT + YF+N ++C LIE+ + GI+++LD+ C G +D T L KL Sbjct: 424 GIPWTKVDYFDNGIICKLIEH--NQRGILAMLDEECL---RPGVVSDSTFLAKLNQLFSK 478 Query: 490 HEHFNS--------------WSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTS 535 H H+ S + F I HYAGKV+Y+V+ F ++N D+LF DL++ M + Sbjct: 479 HGHYESKVTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLLQAMWKA 538 Query: 536 EQAFLRMLFPEKLDGDKK----GRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETK 591 + LR LFPE G+ K RP TAG++ K L+ L +P+YIRCIKPNE + Sbjct: 539 QHPLLRSLFPE---GNPKQASLKRPPTAGAQFKSSVAILMKNLYSKSPNYIRCIKPNEHQ 595 Query: 592 RPRDWEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWPRWRGDERQ 651 + + + V Q YLGL EN+RVRRAG+A+R+ + FL+RY +L+ TWP W G +R+ Sbjct: 596 QRGQFSSDLVATQARYLGLLENVRVRRAGYAHRQGYGPFLERYRLLSRSTWPHWNGGDRE 655 Query: 652 GVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQKAWRRHVAVR 711 GV+ +L ++M + G TK+F+++P++LF LEE R + A IQK +R Sbjct: 656 GVEKVLGELSMSSGELAFGKTKIFIRSPKTLFYLEEQRRLRLQQLATLIQKIYRGWRCRT 715 Query: 712 KYEEMREEASNILLN 726 Y+ MR+ S IL++ Sbjct: 716 HYQLMRK--SQILIS 728 Score = 50.4 bits (119), Expect = 9e-06 Identities = 50/191 (26%), Positives = 88/191 (46%), Gaps = 22/191 (11%) Query: 702 KAWRRHVAVRKYEEMREE--ASNILLNKKERRRNSINRNFVGDYLGLEERPELRQFLGKR 759 K +R ++ ++ E +RE+ AS + KK S+ F GDY+GL+ P+L++ G Sbjct: 830 KRFRDQLSPKQVEILREKLCASELFKGKKASYPQSVPIPFCGDYIGLQGNPKLQKLKGGE 889 Query: 760 E-RVDFADSVTKYDR-RFKPIKRDLILTPKCVYVIGREKVKKGPEKGQVCEVLKKKVDIQ 817 E V A++V K +R K R L+LT V + +K + K + + Sbjct: 890 EGPVLMAEAVKKVNRGNGKTSSRILLLTKGHVILTDTKKSQ-----------AKIVIGLD 938 Query: 818 ALRGVSLSTRQDDFFILQ-------EDAADSFLESVFKTEFVSLLCKRFEEATRRPLPLT 870 + GVS+++ +D F L D L S E ++ + + +AT+R L +T Sbjct: 939 NVAGVSVTSLKDGLFSLHLSEMSSVGSKGDFLLVSEHVIELLTKMYRAVLDATQRQLTVT 998 Query: 871 FSDTLQFRVKK 881 ++ R K+ Sbjct: 999 VTEKFSVRFKE 1009 >gi|51100974 myosin ID [Homo sapiens] Length = 1006 Score = 539 bits (1388), Expect = e-153 Identities = 302/742 (40%), Positives = 446/742 (60%), Gaps = 33/742 (4%) Query: 18 GVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLYQGA 77 G D VL+ ++ ANLR RF I+T+IG V++SVNP+K + + I+ Y+G Sbjct: 10 GKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGR 69 Query: 78 AQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGGEK- 136 YE PPH++A+ D Y+ M ++ C++ISGESGAGKT A+KYIM YI+ ++ ++ Sbjct: 70 ELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRA 129 Query: 137 -VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKS 195 V+ VK+++L+SN +LEAFGNAKT RN+NSSRFGKY +I F G+P GG I+N+LLEKS Sbjct: 130 EVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEKS 189 Query: 196 RVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSDTYQVDGTDDRSDFGE 255 RV++Q ER+FH +YQLL+G S++ ++L L Y +D ++F Sbjct: 190 RVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSINDAAEFRV 249 Query: 256 TLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESVDLLAFPAYLLGIDSG 315 AM+VIG P Q V +++A ILHLGN+ F DG+ +E+ +++ A LL + Sbjct: 250 VADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPLIENGKVVSIIAELLSTKTD 309 Query: 316 RLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDFLVEAINRAMQK 375 +++ L R + + GR + I+ ++A+Y RDA AK +Y RLF ++V IN ++ Sbjct: 310 MVEKALLYRTVAT---GR-DIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEV 365 Query: 376 PQEEYS-------IGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQ 428 + + IGVLDIYGFEIF N FEQFCIN+ NEKLQQ+FI+L LK EQEEY + Sbjct: 366 KNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQR 425 Query: 429 EGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQKLQAAVG 488 EGI W I YFNN+++ DL+E + GI+++LDD C + G D+ L+ L + +G Sbjct: 426 EGIPWKHIDYFNNQIIVDLVEQQ--HKGIIAILDDACMNV---GKVTDEMFLEALNSKLG 480 Query: 489 THEHFNS-----------WSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQ 537 H HF+S + F I HYAG V Y V GF ++N+D LF D LM S Sbjct: 481 KHAHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSN 540 Query: 538 AFLRMLFPE-KLD-GDKKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPRD 595 L+ ++PE KL + RP TA + K LV L P+Y+RCIKPN+ K P+ Sbjct: 541 PVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQI 600 Query: 596 WEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWPRW-RGDERQGVQ 654 +++ R +HQVEYLGL EN+RVRRAGFA+R+ + KFL RY +++ TWP +++ V+ Sbjct: 601 FDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAVK 660 Query: 655 HLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQKAWRRHVAVRKYE 714 L+ + D G TK+F++ P +LF LEE+R + +QK WR +A +Y+ Sbjct: 661 KLIERCGFQ-DDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGTLARMRYK 719 Query: 715 EMREEASNILLNKKERRRNSIN 736 + + I ++ + ++ I+ Sbjct: 720 RTKAALTIIRYYRRYKVKSYIH 741 >gi|239582755 myosin IG [Homo sapiens] Length = 1018 Score = 507 bits (1306), Expect = e-143 Identities = 306/735 (41%), Positives = 422/735 (57%), Gaps = 45/735 (6%) Query: 18 GVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLYQGA 77 G D VLL Q+T + NL+ RF I+TYIG VL+SVNP++++P + I YQG Sbjct: 10 GKPDFVLLDQVTMEDFMRNLQLRFEKGRIYTYIGEVLVSVNPYQELPLYGPEAIARYQGR 69 Query: 78 AQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGGEK- 136 YE PPH+YA+ + Y+ M + C++ISGESGAGKT A+K+IM YI+ V+ ++ Sbjct: 70 ELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKHIMQYIAAVTNPSQRA 129 Query: 137 -VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKS 195 V+ VKD++L+S +LEAFGNA+T RN+NSSRFGKY +I F G+P GG I ++LLEKS Sbjct: 130 EVERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKGDPIGGHIHSYLLEKS 189 Query: 196 RVVMQNENERNFHIYYQLLEGASQEQRQNLGL-MTPDYYYYLNQS-----DTYQVDGTDD 249 RV+ Q+ ERNFH +YQLL G+ +Q L L P Y + +Q + +D+ Sbjct: 190 RVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQGAGLNMTVHSALDSDE 249 Query: 250 RSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISF--CEDGNYAR----VESVDLL 303 +S T AM+VIG P + V +++A ILHLGNI F E+G + V L+ Sbjct: 250 QSHQAVT-EAMRVIGFSPEEVESVHRILAAILHLGNIEFVETEEGGLQKEGLAVAEEALV 308 Query: 304 AFPAYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFD 363 A L + L +R + S GGR E I +A+Y RDA AK +Y RLF+ Sbjct: 309 DHVAELTATPRDLVLRSLLARTVAS--GGR-ELIEKGHTAAEASYARDACAKAVYQRLFE 365 Query: 364 FLVEAINRAMQ-------KPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIE 416 ++V IN M+ + ++ IGVLDIYGFE+F N FEQFCIN+ NEKLQQ+FI+ Sbjct: 366 WVVNRINSVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINYCNEKLQQLFIQ 425 Query: 417 LTLKAEQEEYVQEGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGAD 476 L LK EQEEY +EGI W ++YFNN + DL+E GI++VLD+ C+ + G D Sbjct: 426 LILKQEQEEYEREGITWQSVEYFNNATIVDLVER--PHRGILAVLDEACS---SAGTITD 480 Query: 477 QTLLQKLQAAVGTHEHFNS-----------WSAGFVIHHYAGKVSYDVSGFCERNRDVLF 525 + LQ L H H+ S + F I HYAG V+Y V GF ++NRD LF Sbjct: 481 RIFLQTLDMHHRHHLHYTSRQLCPTDKTMEFGRDFRIKHYAGDVTYSVEGFIDKNRDFLF 540 Query: 526 SDLIELMQTSEQAFLRMLFPEKLDG--DKKGRPSTAGSKIKKQANDLVATLMRCTPHYIR 583 D L+ S LR ++P+ + RP TAG+ K LV L P Y+R Sbjct: 541 QDFKRLLYNSTDPTLRAMWPDGQQDITEVTKRPLTAGTLFKNSMVALVENLASKEPFYVR 600 Query: 584 CIKPNETKRPRDWEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWP 643 CIKPNE K +EN +HQV YLGL EN+RVRRAGFA R+ +++FL RY + TWP Sbjct: 601 CIKPNEDKVAGKLDENHCRHQVAYLGLLENVRVRRAGFASRQPYSRFLLRYKMTCEYTWP 660 Query: 644 -RWRGDERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQK 702 G ++ V LL ++ D G +K+F+++P +L LE+ R R +QK Sbjct: 661 NHLLGSDKAAVSALLEQHGLQGD-VAFGHSKLFIRSPRTLVTLEQSRARLIPIIVLLLQK 719 Query: 703 AWRRHVAVRKYEEMR 717 AWR +A + +R Sbjct: 720 AWRGTLARWRCRRLR 734 >gi|189083802 myosin VIIA isoform 2 [Homo sapiens] Length = 2175 Score = 481 bits (1237), Expect = e-135 Identities = 283/749 (37%), Positives = 422/749 (56%), Gaps = 60/749 (8%) Query: 12 HNVKQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREI 71 H GV+DM+ L + E I NL R+ D I+TY GS+L++VNP++ + ++ I Sbjct: 60 HPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHI 119 Query: 72 DLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVS 131 Y E PPHI+A+ DN Y NM + +QC IISGESGAGKT + K I+ +++ +S Sbjct: 120 RQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAIS 179 Query: 132 GGGEKVQH--VKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISN 189 G QH ++ +L++ P+LEAFGNAKT+RN+NSSRFGKY +I F++ G +G KI Sbjct: 180 G-----QHSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQ 234 Query: 190 FLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSDTYQVDGTDD 249 +LLEKSRV Q +ERN+H++Y +LEG S++Q++ LGL Y YL + +G D Sbjct: 235 YLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVD 294 Query: 250 RSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESVDLLAFP--- 306 ++ SAM+V+ + + +L+A ILHLGN+ + E + +++ ++L P Sbjct: 295 SQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQY-EARTFENLDACEVLFSPSLA 353 Query: 307 --AYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDF 364 A LL ++ L LTSR + + R E+++ L+ EQA RDA KG+Y RLF + Sbjct: 354 TAASLLEVNPPDLMSCLTSRTLIT----RGETVSTPLSREQALDVRDAFVKGIYGRLFVW 409 Query: 365 LVEAINRAMQKPQEE------YSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELT 418 +V+ IN A+ KP + SIG+LDI+GFE F N FEQ CINF NE LQQ F+ Sbjct: 410 IVDKINAAIYKPPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHV 469 Query: 419 LKAEQEEYVQEGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQT 478 K EQEEY E I W I++ +N+ D+I NK P I+S++D+ G D T Sbjct: 470 FKLEQEEYDLESIDWLHIEFTDNQDALDMIANK--PMNIISLIDEESKFPK----GTDTT 523 Query: 479 LLQKLQAAVGTHEHF----NSWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQT 534 +L KL + + ++ N+ F I+H+AG V Y+ GF E+NRD L D+I+L+ + Sbjct: 524 MLHKLNSQHKLNANYIPPKNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHS 583 Query: 535 SEQAFLRMLFPE--KLDGDKKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKR 592 S F++ +F + + + R T S+ K+ L+ TL C P ++RCIKPNE K+ Sbjct: 584 SRNKFIKQIFQADVAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKK 643 Query: 593 PRDWEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWPRWR-GDERQ 651 P ++ + Q+ Y G+ E IR+RRAG+ R F +F++RY +L P P ++ GD R Sbjct: 644 PMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRG 703 Query: 652 GVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRER-------------------- 691 Q + AV D +Q+G TK+F+K+ + LLE R++ Sbjct: 704 TCQRMAEAVLGTHDDWQIGKTKIFLKDHHDM-LLEVERDKAITDRVILLQKVIRGFKDRS 762 Query: 692 ---KFDGFARTIQKAWRRHVAVRKYEEMR 717 K A IQ+ WR H + Y MR Sbjct: 763 NFLKLKNAATLIQRHWRGHNCRKNYGLMR 791 >gi|189083800 myosin VIIA isoform 3 [Homo sapiens] Length = 1204 Score = 481 bits (1237), Expect = e-135 Identities = 283/749 (37%), Positives = 422/749 (56%), Gaps = 60/749 (8%) Query: 12 HNVKQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREI 71 H GV+DM+ L + E I NL R+ D I+TY GS+L++VNP++ + ++ I Sbjct: 60 HPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHI 119 Query: 72 DLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVS 131 Y E PPHI+A+ DN Y NM + +QC IISGESGAGKT + K I+ +++ +S Sbjct: 120 RQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAIS 179 Query: 132 GGGEKVQH--VKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISN 189 G QH ++ +L++ P+LEAFGNAKT+RN+NSSRFGKY +I F++ G +G KI Sbjct: 180 G-----QHSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQ 234 Query: 190 FLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSDTYQVDGTDD 249 +LLEKSRV Q +ERN+H++Y +LEG S++Q++ LGL Y YL + +G D Sbjct: 235 YLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVD 294 Query: 250 RSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESVDLLAFP--- 306 ++ SAM+V+ + + +L+A ILHLGN+ + E + +++ ++L P Sbjct: 295 SQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQY-EARTFENLDACEVLFSPSLA 353 Query: 307 --AYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDF 364 A LL ++ L LTSR + + R E+++ L+ EQA RDA KG+Y RLF + Sbjct: 354 TAASLLEVNPPDLMSCLTSRTLIT----RGETVSTPLSREQALDVRDAFVKGIYGRLFVW 409 Query: 365 LVEAINRAMQKPQEE------YSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELT 418 +V+ IN A+ KP + SIG+LDI+GFE F N FEQ CINF NE LQQ F+ Sbjct: 410 IVDKINAAIYKPPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHV 469 Query: 419 LKAEQEEYVQEGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQT 478 K EQEEY E I W I++ +N+ D+I NK P I+S++D+ G D T Sbjct: 470 FKLEQEEYDLESIDWLHIEFTDNQDALDMIANK--PMNIISLIDEESKFPK----GTDTT 523 Query: 479 LLQKLQAAVGTHEHF----NSWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQT 534 +L KL + + ++ N+ F I+H+AG V Y+ GF E+NRD L D+I+L+ + Sbjct: 524 MLHKLNSQHKLNANYIPPKNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHS 583 Query: 535 SEQAFLRMLFPE--KLDGDKKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKR 592 S F++ +F + + + R T S+ K+ L+ TL C P ++RCIKPNE K+ Sbjct: 584 SRNKFIKQIFQADVAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKK 643 Query: 593 PRDWEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWPRWR-GDERQ 651 P ++ + Q+ Y G+ E IR+RRAG+ R F +F++RY +L P P ++ GD R Sbjct: 644 PMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRG 703 Query: 652 GVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRER-------------------- 691 Q + AV D +Q+G TK+F+K+ + LLE R++ Sbjct: 704 TCQRMAEAVLGTHDDWQIGKTKIFLKDHHDM-LLEVERDKAITDRVILLQKVIRGFKDRS 762 Query: 692 ---KFDGFARTIQKAWRRHVAVRKYEEMR 717 K A IQ+ WR H + Y MR Sbjct: 763 NFLKLKNAATLIQRHWRGHNCRKNYGLMR 791 >gi|189083798 myosin VIIA isoform 1 [Homo sapiens] Length = 2215 Score = 481 bits (1237), Expect = e-135 Identities = 283/749 (37%), Positives = 422/749 (56%), Gaps = 60/749 (8%) Query: 12 HNVKQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREI 71 H GV+DM+ L + E I NL R+ D I+TY GS+L++VNP++ + ++ I Sbjct: 60 HPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHI 119 Query: 72 DLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVS 131 Y E PPHI+A+ DN Y NM + +QC IISGESGAGKT + K I+ +++ +S Sbjct: 120 RQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAIS 179 Query: 132 GGGEKVQH--VKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISN 189 G QH ++ +L++ P+LEAFGNAKT+RN+NSSRFGKY +I F++ G +G KI Sbjct: 180 G-----QHSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQ 234 Query: 190 FLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSDTYQVDGTDD 249 +LLEKSRV Q +ERN+H++Y +LEG S++Q++ LGL Y YL + +G D Sbjct: 235 YLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVD 294 Query: 250 RSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESVDLLAFP--- 306 ++ SAM+V+ + + +L+A ILHLGN+ + E + +++ ++L P Sbjct: 295 SQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQY-EARTFENLDACEVLFSPSLA 353 Query: 307 --AYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDF 364 A LL ++ L LTSR + + R E+++ L+ EQA RDA KG+Y RLF + Sbjct: 354 TAASLLEVNPPDLMSCLTSRTLIT----RGETVSTPLSREQALDVRDAFVKGIYGRLFVW 409 Query: 365 LVEAINRAMQKPQEE------YSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELT 418 +V+ IN A+ KP + SIG+LDI+GFE F N FEQ CINF NE LQQ F+ Sbjct: 410 IVDKINAAIYKPPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHV 469 Query: 419 LKAEQEEYVQEGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQT 478 K EQEEY E I W I++ +N+ D+I NK P I+S++D+ G D T Sbjct: 470 FKLEQEEYDLESIDWLHIEFTDNQDALDMIANK--PMNIISLIDEESKFPK----GTDTT 523 Query: 479 LLQKLQAAVGTHEHF----NSWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQT 534 +L KL + + ++ N+ F I+H+AG V Y+ GF E+NRD L D+I+L+ + Sbjct: 524 MLHKLNSQHKLNANYIPPKNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHS 583 Query: 535 SEQAFLRMLFPE--KLDGDKKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKR 592 S F++ +F + + + R T S+ K+ L+ TL C P ++RCIKPNE K+ Sbjct: 584 SRNKFIKQIFQADVAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKK 643 Query: 593 PRDWEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWPRWR-GDERQ 651 P ++ + Q+ Y G+ E IR+RRAG+ R F +F++RY +L P P ++ GD R Sbjct: 644 PMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRG 703 Query: 652 GVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRER-------------------- 691 Q + AV D +Q+G TK+F+K+ + LLE R++ Sbjct: 704 TCQRMAEAVLGTHDDWQIGKTKIFLKDHHDM-LLEVERDKAITDRVILLQKVIRGFKDRS 762 Query: 692 ---KFDGFARTIQKAWRRHVAVRKYEEMR 717 K A IQ+ WR H + Y MR Sbjct: 763 NFLKLKNAATLIQRHWRGHNCRKNYGLMR 791 >gi|153945715 myosin VC [Homo sapiens] Length = 1742 Score = 473 bits (1216), Expect = e-133 Identities = 282/747 (37%), Positives = 422/747 (56%), Gaps = 43/747 (5%) Query: 18 GVDDMVLLPQITEDAIAANLRKRFMDD-YIFTYIGSVLISVNPFKQMPYFTDREIDLYQG 76 G +D+ L + E A+ NLR RF + I+TY G +L+++NP+KQ+P + D I Y G Sbjct: 68 GENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSG 127 Query: 77 AAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGGEK 136 + PHI+A+ + Y+ M + NQ +I+SGESGAGKTV+A+Y M Y + VS G Sbjct: 128 QNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSN 187 Query: 137 VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSR 196 HV+D +L SNP+ EA GNAKT RN+NSSRFGKY EI F + G +S +LLEKSR Sbjct: 188 A-HVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLLEKSR 246 Query: 197 VVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSDTYQVDGTDDRSDFGET 256 VV Q+ENERN+HI+YQL A Q + ++L L + + + Y ++G +DR++ ET Sbjct: 247 VVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGGNTVIEGVNDRAEMVET 306 Query: 257 LSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESVDLLAFPAY--LLGIDS 314 ++G Q V +++A ILHLGN+ GN S D + LLG++S Sbjct: 307 QKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKVFCELLGLES 366 Query: 315 GRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDFLVEAINRAMQ 374 GR+ + L +RK+ + SE++ + QA RDALAK +YA LFDF+VE IN+A+Q Sbjct: 367 GRVAQWLCNRKIVT----SSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQALQ 422 Query: 375 KPQEEYS-IGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRW 433 ++++ IGVLDIYGFE F N FEQFCIN+ NEKLQQ F K EQEEY++E I W Sbjct: 423 FSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEDIPW 482 Query: 434 TPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQKL-QAAVGTHEH 492 T I +++N+ V DLIE K+ GI+ +LD+ C H G D+ LQKL V + Sbjct: 483 TLIDFYDNQPVIDLIEAKM---GILELLDEECLLPH----GTDENWLQKLYNNFVNRNPL 535 Query: 493 FNS---WSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQAFLRMLFPEK-- 547 F + FVI H+A KV Y GF E+NRD ++ L+E+++ S+ F E Sbjct: 536 FEKPRMSNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENPT 595 Query: 548 -----------------LDGDKKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNET 590 + + K +T GSK + L+ TL TPHY+RCIKPN+ Sbjct: 596 PPSPFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDE 655 Query: 591 KRPRDWEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWPRWRGDER 650 K P +++ R+ Q+ G+ E IR+ + R + +F RY IL + + D++ Sbjct: 656 KLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTKQELSF-SDKK 714 Query: 651 QGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQKAWRRHVAV 710 + + +L + + +QYQ G TK+F + + + LE++R K +QK R + Sbjct: 715 EVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAY-LEKLRLDKLRQSCVMVQKHMRGWLQR 773 Query: 711 RKYEEMREEASNILLNKKERRRNSINR 737 +K+ +RE + +++ + R + ++ + Sbjct: 774 KKF--LRERRAALIIQQYFRGQQTVRK 798 >gi|122937512 myosin VIIB [Homo sapiens] Length = 2116 Score = 473 bits (1216), Expect = e-133 Identities = 291/796 (36%), Positives = 431/796 (54%), Gaps = 66/796 (8%) Query: 12 HNVKQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREI 71 H GVDDM+ L + E + NL R+ I+TY GS+L++VNPF+ +P +T ++ Sbjct: 60 HPNSVQGVDDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQV 119 Query: 72 DLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVS 131 LY E PPH++A+ +N Y +M + +QC IISGESGAGKT K I+ +++ +S Sbjct: 120 QLYYSRHMGELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATIS 179 Query: 132 GGGEKVQH--VKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISN 189 G QH ++ +L++NP+LEAFGNAKT+RN+NSSRFGKY +I F+ G +G +I Sbjct: 180 G-----QHSWIEQQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQ 234 Query: 190 FLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSDTYQVDGTDD 249 FLLEKSRV Q ERN+HI+Y +L G S E +Q L L TP Y+YL + +G +D Sbjct: 235 FLLEKSRVCRQAPEERNYHIFYCMLMGVSAEDKQLLSLGTPSEYHYLTMGNCTSCEGLND 294 Query: 250 RSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESVDLLAFPAY- 308 D+ SAM+++ S V++L+A ILHLGN+ F + +++ D++ PA+ Sbjct: 295 AKDYAHIRSAMKILQFSDSESWDVIKLLAAILHLGNVGFMA-SVFENLDASDVMETPAFP 353 Query: 309 ----LLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDF 364 LL + L++ L + R E + +LN+ QAA RDA KG+Y LF + Sbjct: 354 TVMKLLEVQHQELRDCLIKHTILI----RGEFVTRSLNIAQAADRRDAFVKGIYGHLFLW 409 Query: 365 LVEAINRAMQKPQEE------YSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELT 418 +V+ IN A+ P + +IG+LDI+GFE F+ N FEQ CINF NE LQQ F++ Sbjct: 410 IVKKINAAIFTPPAQDPKNVRRAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHV 469 Query: 419 LKAEQEEYVQEGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQT 478 EQEEY E I W I Y +N+ DL+ L P I+S+LD+ G D T Sbjct: 470 FTMEQEEYRSENISWDYIHYTDNRPTLDLL--ALKPMSIISLLDEESRFPQ----GTDLT 523 Query: 479 LLQKLQAAVGTHEHF----NSWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQT 534 +LQKL + ++ F N A F I H+AG+V Y GF E+NRDVL +D++ L+ + Sbjct: 524 MLQKLNSVHANNKAFLQPKNIHDARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYS 583 Query: 535 SEQAFLRMLFPEKL---------------------DGDKKGRPSTAGSKIKKQANDLVAT 573 S+ FLR +F +L D RPST GS+ K+ + L+ Sbjct: 584 SKNKFLREIFNLELAETKLGHGTIRQAKAGNHLFKSADSNKRPSTLGSQFKQSLDQLMKI 643 Query: 574 LMRCTPHYIRCIKPNETKRPRDWEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQR 633 L C P++IRCIKPNE K+P ++ Q+ Y G+ E + +R++GF R F +F QR Sbjct: 644 LTNCQPYFIRCIKPNEYKKPLLFDRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQR 703 Query: 634 YAILTPETW-PRWRGDERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERK 692 + +L P + +G RQ + ++ G TK+F+++ + LLE R + Sbjct: 704 FGVLLPNAMRMQLQGKLRQMTLGITDVWLRTDKDWKAGKTKIFLRDHQDT-LLEVQRSQV 762 Query: 693 FDGFARTIQKAWRRHVAVRKYEEMREEASNILLNKKERRRNSINRNFVGDYLGLE----- 747 D A +IQK R + +++ R A + + R RNF +G E Sbjct: 763 LDRAALSIQKVLRGYRYRKEFLRQRRAAVTL---QAWWRGYCNRRNFKLILVGFERLQAI 819 Query: 748 --ERPELRQFLGKRER 761 +P RQ+ R+R Sbjct: 820 ARSQPLARQYQAMRQR 835 >gi|118402590 myosin XV [Homo sapiens] Length = 3530 Score = 463 bits (1191), Expect = e-130 Identities = 284/737 (38%), Positives = 411/737 (55%), Gaps = 42/737 (5%) Query: 16 QSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLYQ 75 + GV+DM L + E + +NL+ RF + I+TYIGS+L+SVNP++ + ++ Y Sbjct: 1221 EDGVEDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYN 1280 Query: 76 GAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGGE 135 G A ENPPH++A+ + + ML +NQC+IISGESG+GKT A K I+ Y++ ++ E Sbjct: 1281 GRALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMNQKRE 1340 Query: 136 KVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKS 195 +Q +K IL++ PLLE+FGNAKTVRN+NSSRFGK+ EI F GG G S +LLEKS Sbjct: 1341 VMQQIK--ILEATPLLESFGNAKTVRNDNSSRFGKFVEI-FLEGGVISGAITSQYLLEKS 1397 Query: 196 RVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSDTYQVDGTDDRSDFGE 255 R+V Q +NERN+HI+Y+LL G + RQ L + YYYLNQ ++ G D DF Sbjct: 1398 RIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIAGKSDADDFRR 1457 Query: 256 TLSAMQVIGIPPSIQQLVLQLVAGILHLGNISF----CEDGNYARVESVDLLAFPAYLLG 311 L+AM+V+G Q + +++A ILHLGN+ F + A V S + A LL Sbjct: 1458 LLAAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAREIQAVAELLQ 1517 Query: 312 IDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDFLVEAINR 371 I LQ+ +T + ++ E I L VE A RDA+AK LYA LF +L+ +N Sbjct: 1518 ISPEGLQKAITFKVTET----MREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVNA 1573 Query: 372 AMQKPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGI 431 + Q+ SI +LDIYGFE N FEQ CIN+ NE LQ +F ++ + EQEEY++E I Sbjct: 1574 LVSPRQDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIREQI 1633 Query: 432 RWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQKLQAAVGTHE 491 W I + +N+ +LI L P GI+ +LDD C AT D T LQK G + Sbjct: 1634 DWQEITFADNQPCINLI--SLKPYGILRILDDQCCFPQAT----DHTFLQKCHYHHGANP 1687 Query: 492 HFNSWS---AGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQAFLRMLF---- 544 ++ F I HYAGKV+Y V F ++N D + D+++L S + LF Sbjct: 1688 LYSKPKMPLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVAHLFSSHA 1747 Query: 545 ----PEKLDGD----KKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPRDW 596 P++L + + T +K ++ DLV + RC P ++RC+KPN K P + Sbjct: 1748 PQAAPQRLGKSSSVTRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPNHKKEPGLF 1807 Query: 597 EENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILT--PETWPRWRGDERQGVQ 654 E + V Q+ Y G+ E +R+R+ GF R F F+ RY L P GD V Sbjct: 1808 EPDVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLVALKHDLPA-NGD--MCVS 1864 Query: 655 HLLRAVNMEPDQYQMGSTKVFVKNPESLF-LLEEVRERKFDGFARTIQKAWRRHVAVRKY 713 L R + P+ Y++G +K+F+K E L+ LLE +RE + A T+Q+ R R++ Sbjct: 1865 VLSRLCKVMPNMYRVGVSKLFLK--EHLYQLLESMREHVLNLAALTLQRCLRGFFIKRRF 1922 Query: 714 EEMREEASNILLNKKER 730 +R + ILL + R Sbjct: 1923 RSLRHKI--ILLQSRAR 1937 >gi|154354979 myosin X [Homo sapiens] Length = 2058 Score = 458 bits (1179), Expect = e-128 Identities = 290/753 (38%), Positives = 425/753 (56%), Gaps = 48/753 (6%) Query: 12 HNVKQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMP-YFTDRE 70 H + GVDDM L ++ +I NL +R+ + I+TYIGS+L SVNP++ + + Sbjct: 58 HPTNEEGVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPAT 117 Query: 71 IDLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKV 130 ++ Y E PPHI+A+ + YR + +NQC++ISGESGAGKT + K I+ ++S + Sbjct: 118 MEQYSRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVI 177 Query: 131 SGGG------EKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDG 184 S EK V+ IL+S+P++EAFGNAKTV NNNSSRFGK+ ++ + G G Sbjct: 178 SQQSLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQG 237 Query: 185 GKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSDTYQV 244 G+I ++LLEK+RVV QN ERN+HI+Y LL G E+R+ L TP+ Y+YLNQS + Sbjct: 238 GRIVDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPENYHYLNQSGCVED 297 Query: 245 DGTDDRSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESVDLLA 304 D+ F E ++AM V+ + V +L+AGILHLGNI F G A+V L Sbjct: 298 KTISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEFITAGG-AQVSFKTALG 356 Query: 305 FPAYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDF 364 A LLG+D +L + LT R M R E I LNV+QA +RD+LA LYA F++ Sbjct: 357 RSAELLGLDPTQLTDALTQRSMFL----RGEEILTPLNVQQAVDSRDSLAMALYACCFEW 412 Query: 365 LVEAINRAMQKPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQE 424 +++ IN ++ ++ SIG+LDI+GFE F+ N FEQF IN+ NEKLQ+ F + EQ Sbjct: 413 VIKKINSRIKGNEDFKSIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLEQL 472 Query: 425 EYVQEGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQKLQ 484 EY +EG+ W I + +N DLIE KL G+++++++ AT D TLL+KL Sbjct: 473 EYSREGLVWEDIDWIDNGECLDLIEKKL---GLLALINEESHFPQAT----DSTLLEKLH 525 Query: 485 AA-VGTHEHFNSWSA--GFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQAFLR 541 + H + A F + HYAG+V YDV G E+NRD DL+ L++ S F+ Sbjct: 526 SQHANNHFYVKPRVAVNNFGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIY 585 Query: 542 MLF--------PEKLDGDKKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRP 593 LF + L K R T S+ K + L+ATL P ++RCIKPN K P Sbjct: 586 DLFEHVSSRNNQDTLKCGSKHRRPTVSSQFKDSLHSLMATLSSSNPFFVRCIKPNMQKMP 645 Query: 594 RDWEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAIL-----TPETWPRWRGD 648 +++ V +Q+ Y G+ E +R+R+AG+A RR F F +RY +L PE D Sbjct: 646 DQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLALPE-------D 698 Query: 649 ERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESL-FLLEEVRERKFDGFARTIQKAWRRH 707 R LL+ + ++Q+G TKVF++ ESL LE+ RE + A I+ Sbjct: 699 VRGKCTSLLQLYDASNSEWQLGKTKVFLR--ESLEQKLEKRREEEVSHAAMVIRAHVLGF 756 Query: 708 VAVRKYEEMREEASNILLNKKERRRNSINRNFV 740 +A ++Y R+ +++ +K R + R F+ Sbjct: 757 LARKQY---RKVLYCVVIIQKNYRAFLLRRRFL 786 >gi|122937345 myosin VB [Homo sapiens] Length = 1848 Score = 457 bits (1176), Expect = e-128 Identities = 270/772 (34%), Positives = 426/772 (55%), Gaps = 68/772 (8%) Query: 18 GVDDMVLLPQITEDAIAANLRKRFMD-DYIFTYIGSVLISVNPFKQMPYFTDREIDLYQG 76 G +D+ L + E A+ NL+ RF++ ++I+TY G VL+++NP++Q+P + I Y G Sbjct: 70 GENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSG 129 Query: 77 AAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGGEK 136 + PHI+A+ + Y+ M D +NQ +I+SGESGAGKTV+AKY M Y + V GG Sbjct: 130 QNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATV-GGSAS 188 Query: 137 VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSR 196 ++++ +L S+P++EA GNAKT RN+NSSRFGKY +I F + G + +LLEKSR Sbjct: 189 ETNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYLLEKSR 248 Query: 197 VVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSDTYQVDGTDDRSDFGET 256 VV Q ++ERN+HI+YQL A + + L L + + ++Y +Q ++G DD DF +T Sbjct: 249 VVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVDDAEDFEKT 308 Query: 257 LSAMQVIGIPPSIQQLVLQLVAGILHLGNISFC--EDGNYARVESVDL-LAFPAYLLGID 313 A ++G+ S Q + +++A ILHLG+++ DG+ + D+ L+ LLG++ Sbjct: 309 RQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQDVYLSNFCRLLGVE 368 Query: 314 SGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDFLVEAINRAM 373 +++ L RK+ + SE+ T++++Q R+ALAK +YA+LF ++VE IN+A+ Sbjct: 369 HSQMEHWLCHRKLVT----TSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHINKAL 424 Query: 374 QKPQEEYS-IGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIR 432 +++S IGVLDIYGFE F+ N FEQFCIN+ NEKLQQ F K EQEEY++E I Sbjct: 425 HTSLKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQIP 484 Query: 433 WTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQKLQAAVGTHEH 492 WT I +++N+ DLIE KL GI+ +LD+ C G DQ QKL + +H Sbjct: 485 WTLIDFYDNQPCIDLIEAKL---GILDLLDEECKVPK----GTDQNWAQKLYDRHSSSQH 537 Query: 493 FNS---WSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQAFLRMLFPEKLD 549 F + F+I H+A KV Y GF E+NRD ++ + I +++ S+ + LF + D Sbjct: 538 FQKPRMSNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKD 597 Query: 550 G-------------------------DKKGRPSTAGSKIKKQANDLVATLMRCTPHYIRC 584 K T G + + + L+ TL TPHY+RC Sbjct: 598 PVPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATTPHYVRC 657 Query: 585 IKPNETKRPRDWEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWPR 644 IKPN+ K P ++ R Q+ G+ E IR+ AG+ R + F RY +L + Sbjct: 658 IKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVKKR-EL 716 Query: 645 WRGDERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFL-------------------- 684 D++ + +L + +PD++Q G TK+F + + +L Sbjct: 717 ANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVR 776 Query: 685 --LEEVRERKFDGFARTIQKAWRRHVAVRKYEEMREEASNILLNKKERRRNS 734 L++V+ + G T+Q+ R H+A R E +R + ++L K R + + Sbjct: 777 GWLQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRA 828 >gi|215982794 myosin VA isoform 2 [Homo sapiens] Length = 1828 Score = 455 bits (1171), Expect = e-128 Identities = 278/742 (37%), Positives = 413/742 (55%), Gaps = 57/742 (7%) Query: 18 GVDDMVLLPQITEDAIAANLRKRFMDD-YIFTYIGSVLISVNPFKQMPYFTDREIDLYQG 76 G +D+ L + E A+ NLR RF+D I+TY G VL+++NP++Q+P + + I+ Y G Sbjct: 70 GENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSG 129 Query: 77 AAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGGEK 136 + PHI+A+ + Y+ M D NQ +I+SGESGAGKTV+AKY M Y + VSG + Sbjct: 130 QNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASE 189 Query: 137 VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSR 196 +V++ +L SNP++E+ GNAKT RN+NSSRFGKY EI F + G + +LLEKSR Sbjct: 190 A-NVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSR 248 Query: 197 VVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSDTYQVDGTDDRSDFGET 256 VV Q E ERN+HI+YQL A + + L L D + Y Q + ++G DD + T Sbjct: 249 VVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEMAHT 308 Query: 257 LSAMQVIGIPPSIQQLVLQLVAGILHLGNISF-CEDGNYARV-ESVDLLAFPAYLLGIDS 314 A ++GI S Q + +++AGILHLGN+ F D + + + L L+G+D Sbjct: 309 RQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIFCDLMGVDY 368 Query: 315 GRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDFLVEAINRAMQ 374 + L RK+ + +E+ ++ QA RDALAK +YA+LF+++V+ +N+A+ Sbjct: 369 EEMCHWLCHRKLAT----ATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALH 424 Query: 375 KPQEEYS-IGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRW 433 +++S IGVLDIYGFE F+ N FEQFCIN+ NEKLQQ F K EQEEY++E I W Sbjct: 425 SAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPW 484 Query: 434 TPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQKLQAAVGTH--- 490 T I +++N+ +LIE+KL GI+ +LD+ C G D T QKL TH Sbjct: 485 TLIDFYDNQPCINLIESKL---GILDLLDEECKMPK----GTDDTWAQKL---YNTHLNK 534 Query: 491 ----EHFNSWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQAFLRMLFPE 546 E + F+I H+A KV Y GF E+N+D +F + I+++++S+ L LF + Sbjct: 535 CALFEKPRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQD 594 Query: 547 KLDG--------------------DKKGRP--------STAGSKIKKQANDLVATLMRCT 578 KGRP T G + + + L+ TL T Sbjct: 595 DEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATT 654 Query: 579 PHYIRCIKPNETKRPRDWEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILT 638 PHY+RCIKPN+ K P ++E R Q+ G+ E IR+ AGF R + +F RY +L Sbjct: 655 PHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLM 714 Query: 639 PETWPRWRGDERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFAR 698 + D +Q +++L + ++ D+YQ G TK+F + + + LE++R K Sbjct: 715 KQ--KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAY-LEKLRADKLRAACI 771 Query: 699 TIQKAWRRHVAVRKYEEMREEA 720 IQK R + +KY MR+ A Sbjct: 772 RIQKTIRGWLLRKKYLRMRKAA 793 >gi|215982791 myosin VA isoform 1 [Homo sapiens] Length = 1855 Score = 455 bits (1171), Expect = e-128 Identities = 278/742 (37%), Positives = 413/742 (55%), Gaps = 57/742 (7%) Query: 18 GVDDMVLLPQITEDAIAANLRKRFMDD-YIFTYIGSVLISVNPFKQMPYFTDREIDLYQG 76 G +D+ L + E A+ NLR RF+D I+TY G VL+++NP++Q+P + + I+ Y G Sbjct: 70 GENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSG 129 Query: 77 AAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGGEK 136 + PHI+A+ + Y+ M D NQ +I+SGESGAGKTV+AKY M Y + VSG + Sbjct: 130 QNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASE 189 Query: 137 VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSR 196 +V++ +L SNP++E+ GNAKT RN+NSSRFGKY EI F + G + +LLEKSR Sbjct: 190 A-NVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSR 248 Query: 197 VVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSDTYQVDGTDDRSDFGET 256 VV Q E ERN+HI+YQL A + + L L D + Y Q + ++G DD + T Sbjct: 249 VVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEMAHT 308 Query: 257 LSAMQVIGIPPSIQQLVLQLVAGILHLGNISF-CEDGNYARV-ESVDLLAFPAYLLGIDS 314 A ++GI S Q + +++AGILHLGN+ F D + + + L L+G+D Sbjct: 309 RQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIFCDLMGVDY 368 Query: 315 GRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDFLVEAINRAMQ 374 + L RK+ + +E+ ++ QA RDALAK +YA+LF+++V+ +N+A+ Sbjct: 369 EEMCHWLCHRKLAT----ATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALH 424 Query: 375 KPQEEYS-IGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRW 433 +++S IGVLDIYGFE F+ N FEQFCIN+ NEKLQQ F K EQEEY++E I W Sbjct: 425 SAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPW 484 Query: 434 TPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQKLQAAVGTH--- 490 T I +++N+ +LIE+KL GI+ +LD+ C G D T QKL TH Sbjct: 485 TLIDFYDNQPCINLIESKL---GILDLLDEECKMPK----GTDDTWAQKL---YNTHLNK 534 Query: 491 ----EHFNSWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQAFLRMLFPE 546 E + F+I H+A KV Y GF E+N+D +F + I+++++S+ L LF + Sbjct: 535 CALFEKPRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQD 594 Query: 547 KLDG--------------------DKKGRP--------STAGSKIKKQANDLVATLMRCT 578 KGRP T G + + + L+ TL T Sbjct: 595 DEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATT 654 Query: 579 PHYIRCIKPNETKRPRDWEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILT 638 PHY+RCIKPN+ K P ++E R Q+ G+ E IR+ AGF R + +F RY +L Sbjct: 655 PHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLM 714 Query: 639 PETWPRWRGDERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFAR 698 + D +Q +++L + ++ D+YQ G TK+F + + + LE++R K Sbjct: 715 KQ--KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAY-LEKLRADKLRAACI 771 Query: 699 TIQKAWRRHVAVRKYEEMREEA 720 IQK R + +KY MR+ A Sbjct: 772 RIQKTIRGWLLRKKYLRMRKAA 793 >gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] Length = 1960 Score = 433 bits (1114), Expect = e-121 Identities = 265/737 (35%), Positives = 410/737 (55%), Gaps = 42/737 (5%) Query: 15 KQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLY 74 K S V+DM L + E ++ NL++R+ I+TY G + +NP+K +P +++ +++Y Sbjct: 79 KFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMY 138 Query: 75 QGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGG 134 +G ++E PPHIYA+TD YR+M+ D E+Q ++ +GESGAGKT K ++ Y++ V+ Sbjct: 139 KGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSH 198 Query: 135 EKVQHVKDI---ILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFL 191 + + ++ +LQ+NP+LEAFGNAKTV+N+NSSRFGK+ I F G G I +L Sbjct: 199 KSKKDQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYL 258 Query: 192 LEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSDTYQVDGTDDRS 251 LEKSR + Q + ER FHI+Y LL GA + + +L L + Y +L+ + G D+ Sbjct: 259 LEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLSNGHV-TIPGQQDKD 317 Query: 252 DFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESVDLLAFP--AYL 309 F ET+ AM+++GIP Q +L++++G+L LGNI F ++ N + D A ++L Sbjct: 318 MFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHL 377 Query: 310 LGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDFLVEAI 369 LGI+ + + ++ GR + + EQA + +ALAK Y R+F +LV I Sbjct: 378 LGINVTDFTRGILTPRIKV---GR-DYVQKAQTKEQADFAIEALAKATYERMFRWLVLRI 433 Query: 370 NRAMQKPQEEYS--IGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYV 427 N+A+ K + + + IG+LDI GFEIF N FEQ CIN+ NEKLQQ+F EQEEY Sbjct: 434 NKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQ 493 Query: 428 QEGIRWTPIQYFNNKVVC-DLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQKLQAA 486 +EGI W I + + C DLIE PPGI+++LD+ C AT D++ ++K+ Sbjct: 494 REGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKAT----DKSFVEKVMQE 549 Query: 487 VGTHEHFN-----SWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQAFLR 541 GTH F A F I HYAGKV Y + +N D L ++ L+ S F+ Sbjct: 550 QGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVS 609 Query: 542 MLFPE----------------KLDG---DKKGRPSTAGSKIKKQANDLVATLMRCTPHYI 582 L+ + L G +KG T G K+Q L+ATL P+++ Sbjct: 610 ELWKDVDRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFV 669 Query: 583 RCIKPNETKRPRDWEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETW 642 RCI PN K+ + + V Q+ G+ E IR+ R GF R F +F QRY ILTP + Sbjct: 670 RCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSI 729 Query: 643 PRWRGDERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQK 702 P+ D +Q +++A+ ++ + Y++G +KVF + L LEE R+ K Q Sbjct: 730 PKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFR-AGVLAHLEEERDLKITDVIIGFQA 788 Query: 703 AWRRHVAVRKYEEMREE 719 R ++A + + + +++ Sbjct: 789 CCRGYLARKAFAKRQQQ 805 >gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo sapiens] Length = 1935 Score = 431 bits (1108), Expect = e-120 Identities = 284/800 (35%), Positives = 423/800 (52%), Gaps = 46/800 (5%) Query: 4 KERFHWQSHNVKQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQM 63 KE Q + K ++DM +L + E A+ NL+ R+ I+TY G ++VNP+K + Sbjct: 72 KEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWL 131 Query: 64 PYFTDREIDLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYI 123 P +T + Y+G + E PPHI++++DN Y+ ML D ENQ ++I+GESGAGKTV K + Sbjct: 132 PVYTPEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRV 191 Query: 124 MGYISKVSGGGEKVQH--------VKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQ 175 + Y + ++ G++ + ++D I+Q+NP LEAFGNAKTVRN+NSSRFGK+ I Sbjct: 192 IQYFAVIAAIGDRSKKDQSPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIH 251 Query: 176 FSRGGEPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDY-YY 234 F G+ I +LLEKSRV+ Q + ER++HI+YQ+L E L + Y Y Sbjct: 252 FGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLDMLLITNNPYDYA 311 Query: 235 YLNQSDTYQVDGTDDRSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISF--CEDG 292 +++Q +T V DD + T +A V+G + + +L I+H GN+ F + Sbjct: 312 FISQGET-TVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQRE 370 Query: 293 NYARVESVDLLAFPAYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDA 352 A + + AYL+G++S L + L ++ +E + NV+Q Y A Sbjct: 371 EQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKV----GNEYVTKGQNVQQVIYATGA 426 Query: 353 LAKGLYARLFDFLVEAINRAMQ-KPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQ 411 LAK +Y R+F+++V IN ++ K +Y IGVLDI GFEIF N FEQ CINF NEKLQ Sbjct: 427 LAKAVYERMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQ 486 Query: 412 QIFIELTLKAEQEEYVQEGIRWTPIQYFNNKVVC-DLIENKLSPPGIMSVLDDVCATMHA 470 Q F EQEEY +EGI WT I + + C DLIE P GIMS+L++ C A Sbjct: 487 QFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIE---KPMGIMSILEEECMFPKA 543 Query: 471 TGGGADQTLLQKL-QAAVGTHEHF-------NSWSAGFVIHHYAGKVSYDVSGFCERNRD 522 T D T KL +G +F A F + HYAG V Y++ G+ ++N+D Sbjct: 544 T----DMTFKAKLFDNHLGKSANFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKD 599 Query: 523 VLFSDLIELMQTSEQAFLRMLFPEKLDGD----------KKGRP-STAGSKIKKQANDLV 571 L ++ L Q S L LF D KKG T + ++ N L+ Sbjct: 600 PLNETVVGLYQKSSLKLLSTLFANYAGADAPIEKGKGKAKKGSSFQTVSALHRENLNKLM 659 Query: 572 ATLMRCTPHYIRCIKPNETKRPRDWEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFL 631 L PH++RCI PNETK P + V HQ+ G+ E IR+ R GF R + F Sbjct: 660 TNLRSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFR 719 Query: 632 QRYAILTPETWPRWRG-DERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRE 690 QRY IL P P + D R+G + LL +++++ +QY+ G TKVF K L LLEE+R+ Sbjct: 720 QRYRILNPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFK-AGLLGLLEEMRD 778 Query: 691 RKFDGFARTIQKAWRRHVAVRKYEEMREEASNILLNKKERRRNSINRNFVGDYLGLEERP 750 + IQ R +A +Y+++ E ++L+ + R +N+ L + +P Sbjct: 779 ERLSRIITRIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKP 838 Query: 751 ELRQFLGKRERVDFADSVTK 770 L+ ++E + T+ Sbjct: 839 LLKSAEREKEMASMKEEFTR 858 >gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] Length = 1976 Score = 428 bits (1100), Expect = e-119 Identities = 265/742 (35%), Positives = 412/742 (55%), Gaps = 45/742 (6%) Query: 15 KQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLY 74 K S V+DM L + E ++ NL+ R+ I+TY G + +NP+K +P +++ I++Y Sbjct: 83 KFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMY 142 Query: 75 QGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGG- 133 +G ++E PPHIYA++++ YR ML D E+Q ++ +GESGAGKT K ++ Y++ V+ Sbjct: 143 RGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSH 202 Query: 134 -GEKVQHV----KDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKIS 188 G K ++ + +LQ+NP+LE+FGNAKTV+N+NSSRFGK+ I F G G I Sbjct: 203 KGRKDHNIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIE 262 Query: 189 NFLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSDTYQVDGTD 248 +LLEKSR V Q ++ER FHI+YQLL GA + + +L L + Y +L+ + + G Sbjct: 263 TYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFNNYRFLS-NGYIPIPGQQ 321 Query: 249 DRSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGN--YARVESVDLLAFP 306 D+ +F ET+ AM ++G +L++V+ +L GNISF ++ N A + + Sbjct: 322 DKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQKL 381 Query: 307 AYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDFLV 366 +LLG++ + + ++ GR + + EQA + +ALAK Y RLF +LV Sbjct: 382 CHLLGMNVMEFTRAILTPRIKV---GR-DYVQKAQTKEQADFAVEALAKATYERLFRWLV 437 Query: 367 EAINRAMQKPQEEYS--IGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQE 424 IN+A+ + + + + IG+LDI GFEIF+ N FEQ CIN+ NEKLQQ+F EQE Sbjct: 438 HRINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQE 497 Query: 425 EYVQEGIRWTPIQYFNNKVVC-DLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQKL 483 EY +EGI W I + + C DLIE +PPG++++LD+ C AT D+T ++KL Sbjct: 498 EYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKAT----DKTFVEKL 553 Query: 484 QAAVGTHEHFN-----SWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQA 538 G+H F A F I HYAGKV Y + +N D L ++ L+ S Sbjct: 554 VQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDR 613 Query: 539 FLRMLFP--EKLDG-----------------DKKGRPSTAGSKIKKQANDLVATLMRCTP 579 F+ L+ +++ G KKG T G K+ L+ATL P Sbjct: 614 FVAELWKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNP 673 Query: 580 HYIRCIKPNETKRPRDWEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTP 639 +++RCI PN KR + + V Q+ G+ E IR+ R GF R F +F QRY ILTP Sbjct: 674 NFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTP 733 Query: 640 ETWPRWRGDERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFART 699 P+ D +Q + ++RA+ ++P+ Y++G +K+F + L LEE R+ K Sbjct: 734 NAIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFR-AGVLAHLEEERDLKITDIIIF 792 Query: 700 IQKAWRRHVAVRKYEEMREEAS 721 Q R ++A + + + +++ S Sbjct: 793 FQAVCRGYLARKAFAKKQQQLS 814 >gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo sapiens] Length = 1972 Score = 420 bits (1080), Expect = e-117 Identities = 258/740 (34%), Positives = 403/740 (54%), Gaps = 45/740 (6%) Query: 15 KQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLY 74 K S V+DM L + E ++ NLR+R+ I+TY G + VNP+K +P ++++ +D+Y Sbjct: 83 KFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMY 142 Query: 75 QGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGG- 133 +G ++E PPHIYA+ D YR+ML D E+Q ++ +GESGAGKT K ++ Y++ V+ Sbjct: 143 KGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSH 202 Query: 134 -GEK----VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKIS 188 G+K ++ +LQ+NP+LEAFGNAKTV+N+NSSRFGK+ I F G G I Sbjct: 203 KGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIE 262 Query: 189 NFLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSDTYQVDGTD 248 +LLEKSR + Q +ER FHI+Y ++ GA ++ R +L L + Y +L+ + + Sbjct: 263 TYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLS-NGFVPIPAAQ 321 Query: 249 DRSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESVDLLAFP-- 306 D F ET+ AM ++G Q +L++V+ +L LGNI F ++ N + D A Sbjct: 322 DDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKV 381 Query: 307 AYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDFLV 366 +L+GI+ + + ++ GR + + EQA + +ALAK Y RLF +++ Sbjct: 382 CHLMGINVTDFTRSILTPRIKV---GR-DVVQKAQTKEQADFAVEALAKATYERLFRWIL 437 Query: 367 EAINRAMQKPQEEYS--IGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQE 424 +N+A+ K + + +G+LDI GFEIF+ N FEQ CIN+ NEKLQQ+F EQE Sbjct: 438 TRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQE 497 Query: 425 EYVQEGIRWTPIQYFNNKVVC-DLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQKL 483 EY +EGI W I + + C +LIE +PPG++++LD+ C AT D++ ++KL Sbjct: 498 EYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKAT----DKSFVEKL 553 Query: 484 QAAVGTHEHFN-----SWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQA 538 G+H F F I HYAGKV Y+ S + +N D L ++ L+ S Sbjct: 554 CTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDK 613 Query: 539 FLRMLFPE-------------------KLDGDKKGRPSTAGSKIKKQANDLVATLMRCTP 579 F+ L+ + KKG T G K+Q L+ TL TP Sbjct: 614 FVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTP 673 Query: 580 HYIRCIKPNETKRPRDWEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTP 639 +++RCI PN KR + V Q+ G+ E IR+ R GF R F +F QRY IL Sbjct: 674 NFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAA 733 Query: 640 ETWPRWRGDERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFART 699 P+ D +Q +++A+ ++P+ Y++G +K+F + L LEE R+ K Sbjct: 734 NAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRT-GVLAHLEEERDLKITDVIMA 792 Query: 700 IQKAWRRHVAVRKYEEMREE 719 Q R ++A + + + +++ Sbjct: 793 FQAMCRGYLARKAFAKRQQQ 812 >gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo sapiens] Length = 1938 Score = 420 bits (1080), Expect = e-117 Identities = 258/740 (34%), Positives = 403/740 (54%), Gaps = 45/740 (6%) Query: 15 KQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLY 74 K S V+DM L + E ++ NLR+R+ I+TY G + VNP+K +P ++++ +D+Y Sbjct: 83 KFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMY 142 Query: 75 QGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGG- 133 +G ++E PPHIYA+ D YR+ML D E+Q ++ +GESGAGKT K ++ Y++ V+ Sbjct: 143 KGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSH 202 Query: 134 -GEK----VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKIS 188 G+K ++ +LQ+NP+LEAFGNAKTV+N+NSSRFGK+ I F G G I Sbjct: 203 KGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIE 262 Query: 189 NFLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSDTYQVDGTD 248 +LLEKSR + Q +ER FHI+Y ++ GA ++ R +L L + Y +L+ + + Sbjct: 263 TYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLS-NGFVPIPAAQ 321 Query: 249 DRSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESVDLLAFP-- 306 D F ET+ AM ++G Q +L++V+ +L LGNI F ++ N + D A Sbjct: 322 DDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKV 381 Query: 307 AYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDFLV 366 +L+GI+ + + ++ GR + + EQA + +ALAK Y RLF +++ Sbjct: 382 CHLMGINVTDFTRSILTPRIKV---GR-DVVQKAQTKEQADFAVEALAKATYERLFRWIL 437 Query: 367 EAINRAMQKPQEEYS--IGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQE 424 +N+A+ K + + +G+LDI GFEIF+ N FEQ CIN+ NEKLQQ+F EQE Sbjct: 438 TRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQE 497 Query: 425 EYVQEGIRWTPIQYFNNKVVC-DLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQKL 483 EY +EGI W I + + C +LIE +PPG++++LD+ C AT D++ ++KL Sbjct: 498 EYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKAT----DKSFVEKL 553 Query: 484 QAAVGTHEHFN-----SWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQA 538 G+H F F I HYAGKV Y+ S + +N D L ++ L+ S Sbjct: 554 CTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDK 613 Query: 539 FLRMLFPE-------------------KLDGDKKGRPSTAGSKIKKQANDLVATLMRCTP 579 F+ L+ + KKG T G K+Q L+ TL TP Sbjct: 614 FVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTP 673 Query: 580 HYIRCIKPNETKRPRDWEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTP 639 +++RCI PN KR + V Q+ G+ E IR+ R GF R F +F QRY IL Sbjct: 674 NFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAA 733 Query: 640 ETWPRWRGDERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFART 699 P+ D +Q +++A+ ++P+ Y++G +K+F + L LEE R+ K Sbjct: 734 NAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRT-GVLAHLEEERDLKITDVIMA 792 Query: 700 IQKAWRRHVAVRKYEEMREE 719 Q R ++A + + + +++ Sbjct: 793 FQAMCRGYLARKAFAKRQQQ 812 >gi|156104908 myosin heavy chain 6 [Homo sapiens] Length = 1939 Score = 419 bits (1078), Expect = e-117 Identities = 269/750 (35%), Positives = 397/750 (52%), Gaps = 46/750 (6%) Query: 10 QSHNVKQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDR 69 Q + K ++DM +L + E A+ NL++R+ I+TY G ++VNP+K +P + Sbjct: 78 QQNPPKFDKIEDMAMLTFLHEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAE 137 Query: 70 EIDLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISK 129 + Y+G + E PPHI++++DN Y+ ML D ENQ ++I+GESGAGKTV K ++ Y + Sbjct: 138 VVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAS 197 Query: 130 VSGGGEKVQH---------VKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGG 180 ++ G++ + ++D I+Q+NP LEAFGNAKTVRN+NSSRFGK+ I F G Sbjct: 198 IAAIGDRGKKDNANANKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATG 257 Query: 181 EPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSD 240 + I +LLEKSRV+ Q + ERN+HI+YQ+L E L + Y Y Sbjct: 258 KLASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLDMLLVTNNPYDYAFVSQG 317 Query: 241 TYQVDGTDDRSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCED--GNYARVE 298 V DD + T SA V+G + V +L I+H GN+ F + A + Sbjct: 318 EVSVASIDDSEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPD 377 Query: 299 SVDLLAFPAYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLY 358 + AYL+G++S L + L ++ +E + +V+Q Y+ ALAK +Y Sbjct: 378 GTEDADKSAYLMGLNSADLLKGLCHPRVKV----GNEYVTKGQSVQQVYYSIGALAKAVY 433 Query: 359 ARLFDFLVEAINRAMQ-KPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIEL 417 ++F+++V IN ++ K +Y IGVLDI GFEIF N FEQ CINF NEKLQQ F Sbjct: 434 EKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHH 493 Query: 418 TLKAEQEEYVQEGIRWTPIQYFNNKVVC-DLIENKLSPPGIMSVLDDVCATMHATGGGAD 476 EQEEY +EGI WT I + + C DLIE P GIMS+L++ C AT D Sbjct: 494 MFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIE---KPMGIMSILEEECMFPKAT----D 546 Query: 477 QTLLQKL-QAAVGTHEHF-------NSWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDL 528 T KL +G +F A F + HYAG V Y++ G+ E+N+D L + Sbjct: 547 MTFKAKLYDNHLGKSNNFQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNETV 606 Query: 529 IELMQTSEQAFLRMLFP-----------EKLDGDKKGRP-STAGSKIKKQANDLVATLMR 576 + L Q S + LF + G KKG T + ++ N L+ L Sbjct: 607 VALYQKSSLKLMATLFSSYATADTGDSGKSKGGKKKGSSFQTVSALHRENLNKLMTNLRT 666 Query: 577 CTPHYIRCIKPNETKRPRDWEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAI 636 PH++RCI PNE K P + V HQ+ G+ E IR+ R GF R + F QRY I Sbjct: 667 THPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRI 726 Query: 637 LTPETWPRWRG-DERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDG 695 L P P + D R+G + LL +++++ +QY+ G TKVF K L LLEE+R+ + Sbjct: 727 LNPVAIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFK-AGLLGLLEEMRDERLSR 785 Query: 696 FARTIQKAWRRHVAVRKYEEMREEASNILL 725 +Q R + +++++ E +L+ Sbjct: 786 IITRMQAQARGQLMRIEFKKIVERRDALLV 815 >gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] Length = 1995 Score = 419 bits (1077), Expect = e-117 Identities = 265/740 (35%), Positives = 407/740 (55%), Gaps = 44/740 (5%) Query: 15 KQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLY 74 K S +DM L + E ++ NLR+R+ I+TY G + +NP+KQ+P +T+ +++Y Sbjct: 103 KFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMY 162 Query: 75 QGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGG- 133 +G ++E PPH+YA+T+ YR+ML D E+Q ++ +GESGAGKT K ++ Y++ V+ Sbjct: 163 RGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSP 222 Query: 134 -GEKVQHV----KDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKIS 188 G K V + +LQ+NP+LEAFGNAKTV+N+NSSRFGK+ I F G G I Sbjct: 223 KGRKEPGVPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIE 282 Query: 189 NFLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSDTYQVDGTD 248 +LLEKSR + Q ++E +FHI+YQLL GA ++ + +L L +Y +L + Sbjct: 283 TYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPG--Q 340 Query: 249 DRSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESVDLLAFP-- 306 +R F ETL +++V+G +L++V+ +L GNI+ + N + D A Sbjct: 341 ERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKL 400 Query: 307 AYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDFLV 366 LLG+ L + ++ GR + + EQA + +ALAK Y RLF +LV Sbjct: 401 CRLLGLGVTDFSRALLTPRIKV---GR-DYVQKAQTKEQADFALEALAKATYERLFRWLV 456 Query: 367 EAINRAMQK-PQEEYS-IGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQE 424 +NRA+ + P++ S +G+LDI GFEIFQ N FEQ CIN+ NEKLQQ+F EQE Sbjct: 457 LRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQE 516 Query: 425 EYVQEGIRWTPIQYFNNKVVC-DLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQKL 483 EY +EGI WT + + + C DLIE +PPG++++LD+ C AT D++ ++K+ Sbjct: 517 EYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKAT----DKSFVEKV 572 Query: 484 QAAVGTHEHFN-----SWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQA 538 G H F A F + HYAGKV Y + + +N D L ++ L+ S Sbjct: 573 AQEQGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDR 632 Query: 539 FLRMLFPEKL------------DGDKKGRP-----STAGSKIKKQANDLVATLMRCTPHY 581 ++ + DG GRP T G K+ + L+ATL P + Sbjct: 633 LTAEIWKDVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSF 692 Query: 582 IRCIKPNETKRPRDWEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPET 641 +RCI PN KR E V Q+ G+ E IR+ R GF R F +F QRY ILTP Sbjct: 693 VRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNA 752 Query: 642 WPRWRGDERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQ 701 P+ D +Q + +++A+ ++P+ Y++G +K+F + L LEE R+ K + Q Sbjct: 753 IPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFR-AGVLAQLEEERDLKVTDIIVSFQ 811 Query: 702 KAWRRHVAVRKYEEMREEAS 721 A R ++A R +++ +++ S Sbjct: 812 AAARGYLARRAFQKRQQQQS 831 >gi|92859701 myosin VI [Homo sapiens] Length = 1285 Score = 419 bits (1076), Expect = e-116 Identities = 266/736 (36%), Positives = 398/736 (54%), Gaps = 63/736 (8%) Query: 19 VDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMP-YFTDREIDLYQGA 77 V+D L + E + N++ R+ D I+TY+ ++LI+VNP+ +P ++ I YQG Sbjct: 59 VEDNCSLMYLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSEAIKSYQGK 118 Query: 78 AQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGGEKV 137 + PPH++A+ D +R+M + +Q +I+SGESGAGKT K+++ Y+++ G G Sbjct: 119 SLGTRPPHVFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLTESYGTG--- 175 Query: 138 QHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSRV 197 Q + D I+++NPLLEAFGNAKTVRNNNSSRFGK+ EI F+ GG +S++LLEKSR+ Sbjct: 176 QDIDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYLLEKSRI 235 Query: 198 VMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLN-------------------- 237 +Q + ERN+HI+Y+L GAS++ R+ L L +PD + YLN Sbjct: 236 CVQGKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKETDKQILQNR 295 Query: 238 QSDTYQVDGT------DDRSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCED 291 +S Y G+ DD DF +AM+ IG+ + + ++VAG+LHLGNI F E Sbjct: 296 KSPEYLKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFEEA 355 Query: 292 GNYA-----RVESVDLLAFPAYLLGIDSGRLQEKLTSRKMDSRWGG-RSESINVTLNVEQ 345 G+ + + +S L + A LLG+D L+ LT+R M + GG + I V L VEQ Sbjct: 356 GSTSGGCNLKNKSAQSLEYCAELLGLDQDDLRVSLTTRVMLTTAGGTKGTVIKVPLKVEQ 415 Query: 346 AAYTRDALAKGLYARLFDFLVEAINRAMQKPQEEYSIGVLDIYGFEIFQKNGFEQFCINF 405 A RDALAK +Y+ LFD +V +N+ Y IGVLDI GFE F+ N FEQFCIN+ Sbjct: 416 ANNARDALAKTVYSHLFDHVVNRVNQCFPFETSSYFIGVLDIAGFEYFEHNSFEQFCINY 475 Query: 406 VNEKLQQIFIELTLKAEQEEYVQEGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDD-- 463 NEKLQQ F E LK EQE Y +EG+ + Y +N+ DLIE KL GI+ +LD+ Sbjct: 476 CNEKLQQFFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDLIEAKL--VGILDILDEEN 533 Query: 464 ---VCATMHATGGGADQ-------TLLQKLQAAVGTHEHFNSWSAGFVIHHYAGKVSYDV 513 + H T + T+ +K + AV H + GF+I H+AG V Y+ Sbjct: 534 RLPQPSDQHFTSAVHQKHKDHFRLTIPRKSKLAV--HRNIRD-DEGFIIRHFAGAVCYET 590 Query: 514 SGFCERNRDVLFSDLIELMQTSEQAFLRMLFPEKLDGDKKGRPS-------TAGSKIKKQ 566 + F E+N D L L L+ S F+R LF + +K + + G+K K Q Sbjct: 591 TQFVEKNNDALHMSLESLICESRDKFIRELFESSTNNNKDTKQKAGKLSFISVGNKFKTQ 650 Query: 567 ANDLVATLMRCTPHYIRCIKPNETKRPRDWEENRVKHQVEYLGLKENIRVRRAGFAYRRQ 626 N L+ L +IRCIKPN +E ++ Q++ G+ + + + G+ R Sbjct: 651 LNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVLDLMQGGYPSRAS 710 Query: 627 FAKFLQRYAILTPETWPRWRGDERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLE 686 F + Y P+ R D R + L +A+ + + Y+ G TKVF + P + Sbjct: 711 FHELYNMYKKYMPDKLARL--DPRLFCKALFKALGLNENDYKFGLTKVFFR-PGKFAEFD 767 Query: 687 EVRERKFDGFARTIQK 702 ++ + D A +++ Sbjct: 768 QIMKSDPDHLAELVKR 783 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.137 0.408 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 43,635,378 Number of Sequences: 37866 Number of extensions: 2190507 Number of successful extensions: 9627 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 257 Number of HSP's successfully gapped in prelim test: 361 Number of HSP's that attempted gapping in prelim test: 8018 Number of HSP's gapped (non-prelim): 1393 length of query: 1098 length of database: 18,247,518 effective HSP length: 113 effective length of query: 985 effective length of database: 13,968,660 effective search space: 13759130100 effective search space used: 13759130100 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.