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Search of human proteins with 27502386
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27502386 nuclear factor of activated T-cells, cytosolic
component 1 isoform C [Homo sapiens]
(930 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27502386 nuclear factor of activated T-cells, cytosolic compo... 1929 0.0
gi|27502391 nuclear factor of activated T-cells, cytosolic compo... 1682 0.0
gi|19923350 nuclear factor of activated T-cells, cytosolic compo... 1625 0.0
gi|27502393 nuclear factor of activated T-cells, cytosolic compo... 1352 0.0
gi|27502388 nuclear factor of activated T-cells, cytosolic compo... 726 0.0
gi|27886541 nuclear factor of activated T-cells, cytoplasmic, ca... 612 e-175
gi|27886539 nuclear factor of activated T-cells, cytoplasmic, ca... 600 e-171
gi|209862843 nuclear factor of activated T-cells, cytoplasmic, c... 595 e-170
gi|27886561 nuclear factor of activated T-cells, cytoplasmic, ca... 559 e-159
gi|27886559 nuclear factor of activated T-cells, cytoplasmic, ca... 559 e-159
gi|27886555 nuclear factor of activated T-cells, cytoplasmic, ca... 559 e-159
gi|4758804 nuclear factor of activated T-cells, cytoplasmic, cal... 559 e-159
gi|27886563 nuclear factor of activated T-cells, cytoplasmic, ca... 439 e-123
gi|209862845 nuclear factor of activated T-cells, cytoplasmic, c... 436 e-122
gi|27886520 nuclear factor of activated T-cells 5 isoform a [Hom... 218 2e-56
gi|5729945 nuclear factor of activated T-cells 5 isoform c [Homo... 218 2e-56
gi|164419746 nuclear factor of activated T-cells 5 isoform d [Ho... 218 2e-56
gi|164419744 nuclear factor of activated T-cells 5 isoform b [Ho... 218 2e-56
gi|27886524 nuclear factor of activated T-cells 5 isoform a [Hom... 218 2e-56
gi|157168329 formin 1 [Homo sapiens] 71 5e-12
gi|33286436 gametogenetin [Homo sapiens] 66 2e-10
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 65 3e-10
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 65 4e-10
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 63 1e-09
gi|223468681 v-rel reticuloendotheliosis viral oncogene homolog ... 62 3e-09
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 62 3e-09
gi|223468676 v-rel reticuloendotheliosis viral oncogene homolog ... 61 6e-09
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 60 7e-09
gi|50345997 E1A binding protein p300 [Homo sapiens] 60 9e-09
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 60 9e-09
>gi|27502386 nuclear factor of activated T-cells, cytosolic
component 1 isoform C [Homo sapiens]
Length = 930
Score = 1929 bits (4997), Expect = 0.0
Identities = 930/930 (100%), Positives = 930/930 (100%)
Query: 1 MTGLEDQEFDFEFLFEFNQRDEGAAAAAPEHYGYASSNVSPALPLPTAHSTLPAPCHNLQ 60
MTGLEDQEFDFEFLFEFNQRDEGAAAAAPEHYGYASSNVSPALPLPTAHSTLPAPCHNLQ
Sbjct: 1 MTGLEDQEFDFEFLFEFNQRDEGAAAAAPEHYGYASSNVSPALPLPTAHSTLPAPCHNLQ 60
Query: 61 TSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNN 120
TSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNN
Sbjct: 61 TSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNN 120
Query: 121 QFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNY 180
QFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNY
Sbjct: 121 QFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNY 180
Query: 181 SYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLG 240
SYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLG
Sbjct: 181 SYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLG 240
Query: 241 ARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIV 300
ARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIV
Sbjct: 241 ARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIV 300
Query: 301 AAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSS 360
AAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSS
Sbjct: 301 AAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSS 360
Query: 361 FQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQ 420
FQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQ
Sbjct: 361 FQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQ 420
Query: 421 PKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQ 480
PKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQ
Sbjct: 421 PKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQ 480
Query: 481 VHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLRNSDIELRKGETDI 540
VHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLRNSDIELRKGETDI
Sbjct: 481 VHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLRNSDIELRKGETDI 540
Query: 541 GRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKK 600
GRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKK
Sbjct: 541 GRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKK 600
Query: 601 MVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVH 660
MVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVH
Sbjct: 601 MVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVH 660
Query: 661 VSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQ 720
VSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQ
Sbjct: 661 VSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQ 720
Query: 721 LAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQP 780
LAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQP
Sbjct: 721 LAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQP 780
Query: 781 AGEAPAVQDVPRPVATHPGSPGQPPPALLPQQVSAPPSSSCPPGLEHSLCPSSPSPPLPP 840
AGEAPAVQDVPRPVATHPGSPGQPPPALLPQQVSAPPSSSCPPGLEHSLCPSSPSPPLPP
Sbjct: 781 AGEAPAVQDVPRPVATHPGSPGQPPPALLPQQVSAPPSSSCPPGLEHSLCPSSPSPPLPP 840
Query: 841 ATQEPTCLQPCSPACPPATGRPQHLPSTVRRDESPTAGPRLLPEVHEDGSPNLAPIPVTV 900
ATQEPTCLQPCSPACPPATGRPQHLPSTVRRDESPTAGPRLLPEVHEDGSPNLAPIPVTV
Sbjct: 841 ATQEPTCLQPCSPACPPATGRPQHLPSTVRRDESPTAGPRLLPEVHEDGSPNLAPIPVTV 900
Query: 901 KREPEELDQLYLDDVNEIIRNDLSSTSTHS 930
KREPEELDQLYLDDVNEIIRNDLSSTSTHS
Sbjct: 901 KREPEELDQLYLDDVNEIIRNDLSSTSTHS 930
>gi|27502391 nuclear factor of activated T-cells, cytosolic
component 1 isoform E [Homo sapiens]
Length = 812
Score = 1682 bits (4355), Expect = 0.0
Identities = 812/812 (100%), Positives = 812/812 (100%)
Query: 1 MTGLEDQEFDFEFLFEFNQRDEGAAAAAPEHYGYASSNVSPALPLPTAHSTLPAPCHNLQ 60
MTGLEDQEFDFEFLFEFNQRDEGAAAAAPEHYGYASSNVSPALPLPTAHSTLPAPCHNLQ
Sbjct: 1 MTGLEDQEFDFEFLFEFNQRDEGAAAAAPEHYGYASSNVSPALPLPTAHSTLPAPCHNLQ 60
Query: 61 TSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNN 120
TSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNN
Sbjct: 61 TSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNN 120
Query: 121 QFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNY 180
QFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNY
Sbjct: 121 QFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNY 180
Query: 181 SYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLG 240
SYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLG
Sbjct: 181 SYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLG 240
Query: 241 ARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIV 300
ARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIV
Sbjct: 241 ARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIV 300
Query: 301 AAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSS 360
AAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSS
Sbjct: 301 AAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSS 360
Query: 361 FQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQ 420
FQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQ
Sbjct: 361 FQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQ 420
Query: 421 PKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQ 480
PKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQ
Sbjct: 421 PKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQ 480
Query: 481 VHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLRNSDIELRKGETDI 540
VHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLRNSDIELRKGETDI
Sbjct: 481 VHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLRNSDIELRKGETDI 540
Query: 541 GRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKK 600
GRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKK
Sbjct: 541 GRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKK 600
Query: 601 MVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVH 660
MVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVH
Sbjct: 601 MVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVH 660
Query: 661 VSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQ 720
VSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQ
Sbjct: 661 VSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQ 720
Query: 721 LAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQP 780
LAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQP
Sbjct: 721 LAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQP 780
Query: 781 AGEAPAVQDVPRPVATHPGSPGQPPPALLPQQ 812
AGEAPAVQDVPRPVATHPGSPGQPPPALLPQQ
Sbjct: 781 AGEAPAVQDVPRPVATHPGSPGQPPPALLPQQ 812
>gi|19923350 nuclear factor of activated T-cells, cytosolic
component 1 isoform B [Homo sapiens]
Length = 825
Score = 1625 bits (4207), Expect = 0.0
Identities = 784/787 (99%), Positives = 785/787 (99%)
Query: 26 AAAPEHYGYASSNVSPALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPA 85
+A EHYGYASSNVSPALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPA
Sbjct: 39 SAEEEHYGYASSNVSPALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPA 98
Query: 86 GYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLS 145
GYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLS
Sbjct: 99 GYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLS 158
Query: 146 LPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPE 205
LPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPE
Sbjct: 159 LPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPE 218
Query: 206 EGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYS 265
EGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYS
Sbjct: 219 EGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYS 278
Query: 266 PHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKT 325
PHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKT
Sbjct: 279 PHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKT 338
Query: 326 TLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAK 385
TLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAK
Sbjct: 339 TLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAK 398
Query: 386 PKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGH 445
PKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGH
Sbjct: 399 PKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGH 458
Query: 446 PIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLE 505
PIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLE
Sbjct: 459 PIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLE 518
Query: 506 IPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSL 565
IPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSL
Sbjct: 519 IPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSL 578
Query: 566 QVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHH 625
QVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHH
Sbjct: 579 QVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHH 638
Query: 626 VWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANV 685
VWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANV
Sbjct: 639 VWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANV 698
Query: 686 PIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLM 745
PIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLM
Sbjct: 699 PIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLM 758
Query: 746 PAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPP 805
PAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPP
Sbjct: 759 PAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPP 818
Query: 806 PALLPQQ 812
PALLPQQ
Sbjct: 819 PALLPQQ 825
>gi|27502393 nuclear factor of activated T-cells, cytosolic
component 1 isoform A [Homo sapiens]
Length = 716
Score = 1352 bits (3499), Expect = 0.0
Identities = 656/659 (99%), Positives = 657/659 (99%)
Query: 26 AAAPEHYGYASSNVSPALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPA 85
+A EHYGYASSNVSPALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPA
Sbjct: 39 SAEEEHYGYASSNVSPALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPA 98
Query: 86 GYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLS 145
GYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLS
Sbjct: 99 GYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLS 158
Query: 146 LPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPE 205
LPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPE
Sbjct: 159 LPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPE 218
Query: 206 EGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYS 265
EGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYS
Sbjct: 219 EGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYS 278
Query: 266 PHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKT 325
PHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKT
Sbjct: 279 PHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKT 338
Query: 326 TLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAK 385
TLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAK
Sbjct: 339 TLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAK 398
Query: 386 PKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGH 445
PKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGH
Sbjct: 399 PKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGH 458
Query: 446 PIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLE 505
PIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLE
Sbjct: 459 PIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLE 518
Query: 506 IPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSL 565
IPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSL
Sbjct: 519 IPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSL 578
Query: 566 QVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHH 625
QVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHH
Sbjct: 579 QVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHH 638
Query: 626 VWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPAN 684
VWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPAN
Sbjct: 639 VWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPAN 697
>gi|27502388 nuclear factor of activated T-cells, cytosolic
component 1 isoform D [Homo sapiens]
Length = 353
Score = 726 bits (1874), Expect = 0.0
Identities = 353/353 (100%), Positives = 353/353 (100%)
Query: 460 MLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVID 519
MLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVID
Sbjct: 1 MLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVID 60
Query: 520 CAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSA 579
CAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSA
Sbjct: 61 CAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSA 120
Query: 580 QELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCK 639
QELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCK
Sbjct: 121 QELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCK 180
Query: 640 PNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYEPA 699
PNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYEPA
Sbjct: 181 PNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYEPA 240
Query: 700 PTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLS 759
PTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLS
Sbjct: 241 PTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLS 300
Query: 760 PAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPPPALLPQQ 812
PAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPPPALLPQQ
Sbjct: 301 PAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPPPALLPQQ 353
>gi|27886541 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 2 isoform C [Homo sapiens]
Length = 925
Score = 612 bits (1578), Expect = e-175
Identities = 418/974 (42%), Positives = 530/974 (54%), Gaps = 130/974 (13%)
Query: 3 GLEDQEFDFEFLFEFNQRDEGAAAAAPEHYGYASSNVSPALPLPTAHSTLPAPCHNLQTS 62
G E DF LF++ + P + AS PA P + L+
Sbjct: 22 GSPQDELDFSILFDYEYLNPNEEE--PNAHKVASPPSGPAYPDDVLD-------YGLKPY 72
Query: 63 TPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQF 122
+P + P +G GP FLS+ +P GA L SPRIEIT H Q
Sbjct: 73 SPLASLSGEPPGRFGEPDRVGPQK-FLSAA--KPAGASGL-SPRIEITPS----HELIQA 124
Query: 123 FHDVEVEDVLPSSKRSPSTA-------TLSLPSLEAYRDPSCLSPASSLSSRSCNSEASS 175
+ + D ++ P TL +P E YR+P CLSPASS SS S
Sbjct: 125 VGPLRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGYREPLCLSPASSGSSAS------- 177
Query: 176 YESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTE 235
+ S SP+ SPCVSP P++ P+ SPR SP SPR S+ E
Sbjct: 178 --------FISDTFSPYTSPCVSPNNGGPDDLCPQFQNIPAHY-SPRTSPIMSPRTSLAE 228
Query: 236 ESWLGARS------SRPASPCNKRKYS----LNGRQPPYSPHHSPTPSPHGSPRVSVTDD 285
+S LG S SR +SP KR++S L P SP S +PSP S V+ D
Sbjct: 229 DSCLGRHSPVPRPASRSSSPGAKRRHSCAEALVALPPGASPQRSRSPSPQPSSHVAPQDH 288
Query: 286 -SWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDL 344
S G S+ I+ A+N+L TDS G+P K KT+ + P +
Sbjct: 289 GSPAGYPPVAGSAVIMDALNSLATDSPC----GIPPKMWKTSPDPSP------------V 332
Query: 345 GSPPPPADFAPEDYSSFQHI-------RKGGFCDQYLAVPQHPYQWAKPKPLSP-----T 392
+ P A Y + + + R+ + L VP W PKPL P +
Sbjct: 333 SAAPSKAGLPRHIYPAVEFLGPCEQGERRNSAPESILLVPP---TW--PKPLVPAIPICS 387
Query: 393 SYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHG 452
++ +LP L+W L S SG YELRIEVQPK HHRAHYETEGSRGAVKA GGHP+VQLHG
Sbjct: 388 IPVTASLPPLEWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVVQLHG 447
Query: 453 YLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPEN 512
Y+EN+PL LQ+FIGTAD+R+L+PHAFYQVHRITGKTV+TTS+E I+ NTKVLEIPL P+N
Sbjct: 448 YMENKPLGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPLEPKN 507
Query: 513 SMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPI 572
+MRA IDCAGILKLRN+DIELRKGETDIGRKNTRVRLVFRVH+P+ SGR +SLQ ASNPI
Sbjct: 508 NMRATIDCAGILKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIVSLQTASNPI 567
Query: 573 ECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAK 632
ECSQRSA ELP+VE+Q TDS V GG++M+L+G NF +SKV+F EK DG +WEMEA
Sbjct: 568 ECSQRSAHELPMVERQDTDSCLVYGGQQMILTGQNFTSESKVVFTEKTTDGQQIWEMEAT 627
Query: 633 TDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEP 692
D+D +PN L VEIP +RN+ I +PV V+FYV NGKRKRSQ Q FTY P VP IKTEP
Sbjct: 628 VDKDKSQPNMLFVEIPEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHP--VPAIKTEP 685
Query: 693 TDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVS 752
TD+Y+P C P GL +PYY Q + P SCLVA PC Q T + ++P
Sbjct: 686 TDEYDPTLICSPTHGGLG--SQPYYPQHPMVAESP-SCLVATMAPCQQFRTGL-SSPDAR 741
Query: 753 PKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAP--AVQDVPRPVATHPGSPGQPPPALLP 810
+ + + Y + S LG QPA A ++ D R V H GS GQ L P
Sbjct: 742 YQQQNPAAVLYQRS-KSLSPSLLGYQQPALMAAPLSLADAHRSVLVHAGSQGQSSALLHP 800
Query: 811 QQVSAPPSSSCPPGLEHSLCPSSPSPPLPPATQEPTC--------LQPCSPACPPATGRP 862
+P + P + +S P Q+ C + C P T RP
Sbjct: 801 ----SPTNQQASPVIHYS-----------PTNQQLRCGSHQEFQHIMYCENFA-PGTTRP 844
Query: 863 QHLPSTVRRDESPTAGPRLLPEVH-------EDGSP-----NLAPIPVTVKREPEELDQL 910
P + + SP + P ++ + + ++G P + P VT+K+E + LDQ
Sbjct: 845 GPPPVSQGQRLSPGSYPTVIQQQNATSQRAAKNGPPVSDQKEVLPAGVTIKQE-QNLDQT 903
Query: 911 YLDDVNEIIRNDLS 924
YLDDVNEIIR + S
Sbjct: 904 YLDDVNEIIRKEFS 917
>gi|27886539 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 2 isoform B [Homo sapiens]
Length = 921
Score = 600 bits (1547), Expect = e-171
Identities = 415/974 (42%), Positives = 527/974 (54%), Gaps = 132/974 (13%)
Query: 3 GLEDQEFDFEFLFEFNQRDEGAAAAAPEHYGYASSNVSPALPLPTAHSTLPAPCHNLQTS 62
G E DF LF++ + P + AS PA P + L+
Sbjct: 22 GSPQDELDFSILFDYEYLNPNEEE--PNAHKVASPPSGPAYPDDVLD-------YGLKPY 72
Query: 63 TPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQF 122
+P + P +G GP FLS+ +P GA L SPRIEIT H Q
Sbjct: 73 SPLASLSGEPPGRFGEPDRVGPQK-FLSAA--KPAGASGL-SPRIEITPS----HELIQA 124
Query: 123 FHDVEVEDVLPSSKRSPSTA-------TLSLPSLEAYRDPSCLSPASSLSSRSCNSEASS 175
+ + D ++ P TL +P E YR+P CLSPASS SS S
Sbjct: 125 VGPLRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGYREPLCLSPASSGSSAS------- 177
Query: 176 YESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTE 235
+ S SP+ SPCVSP P++ P+ SPR SP SPR S+ E
Sbjct: 178 --------FISDTFSPYTSPCVSPNNGGPDDLCPQFQNIPAHY-SPRTSPIMSPRTSLAE 228
Query: 236 ESWLGARS------SRPASPCNKRKYS----LNGRQPPYSPHHSPTPSPHGSPRVSVTDD 285
+S LG S SR +SP KR++S L P SP S +PSP S V+ D
Sbjct: 229 DSCLGRHSPVPRPASRSSSPGAKRRHSCAEALVALPPGASPQRSRSPSPQPSSHVAPQDH 288
Query: 286 -SWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDL 344
S G S+ I+ A+N+L TDS G+P K KT+ + P +
Sbjct: 289 GSPAGYPPVAGSAVIMDALNSLATDSPC----GIPPKMWKTSPDPSP------------V 332
Query: 345 GSPPPPADFAPEDYSSFQHI-------RKGGFCDQYLAVPQHPYQWAKPKPLSP-----T 392
+ P A Y + + + R+ + L VP W PKPL P +
Sbjct: 333 SAAPSKAGLPRHIYPAVEFLGPCEQGERRNSAPESILLVPP---TW--PKPLVPAIPICS 387
Query: 393 SYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHG 452
++ +LP L+W L S SG YELRIEVQPK HHRAHYETEGSRGAVKA GGHP+VQLHG
Sbjct: 388 IPVTASLPPLEWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVVQLHG 447
Query: 453 YLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPEN 512
Y+EN+PL LQ+FIGTAD+R+L+PHAFYQVHRITGKTV+TTS+E I+ NTKVLEIPL P+N
Sbjct: 448 YMENKPLGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPLEPKN 507
Query: 513 SMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPI 572
+MRA IDCAGILKLRN+DIELRKGETDIGRKNTRVRLVFRVH+P+ SGR +SLQ ASNPI
Sbjct: 508 NMRATIDCAGILKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIVSLQTASNPI 567
Query: 573 ECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAK 632
ECSQRSA ELP+VE+Q TDS V GG++M+L+G NF +SKV+F EK DG +WEMEA
Sbjct: 568 ECSQRSAHELPMVERQDTDSCLVYGGQQMILTGQNFTSESKVVFTEKTTDGQQIWEMEAT 627
Query: 633 TDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEP 692
D+D +PN L VEIP +RN+ I +PV V+FYV NGKRKRSQ Q FTY P VP IKTEP
Sbjct: 628 VDKDKSQPNMLFVEIPEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHP--VPAIKTEP 685
Query: 693 TDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVS 752
TD+Y+P C P GL +PYY Q + P SCLVA PC Q T + ++P
Sbjct: 686 TDEYDPTLICSPTHGGLG--SQPYYPQHPMVAESP-SCLVATMAPCQQFRTGL-SSPDAR 741
Query: 753 PKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAP--AVQDVPRPVATHPGSPGQPPPALLP 810
+ + + Y + S LG QPA A ++ D R V H GS GQ L P
Sbjct: 742 YQQQNPAAVLYQRS-KSLSPSLLGYQQPALMAAPLSLADAHRSVLVHAGSQGQSSALLHP 800
Query: 811 QQVSAPPSSSCPPGLEHSLCPSSPSPPLPPATQEPTC--------LQPCSPACPPATGRP 862
+P + P + +S P Q+ C + C P T RP
Sbjct: 801 ----SPTNQQASPVIHYS-----------PTNQQLRCGSHQEFQHIMYCENFA-PGTTRP 844
Query: 863 QHLPSTVRRDESPTAGPRLLPEVH-------EDGSP-----NLAPIPVTVKREPEELDQL 910
P + + SP + P ++ + + ++G P + P VT+K+E + LDQ
Sbjct: 845 GPPPVSQGQRLSPGSYPTVIQQQNATSQRAAKNGPPVSDQKEVLPAGVTIKQE-QNLDQT 903
Query: 911 YLDDVNEIIRNDLS 924
YLDD E+I LS
Sbjct: 904 YLDD--ELIDTHLS 915
>gi|209862843 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 2 isoform D [Homo sapiens]
Length = 901
Score = 595 bits (1533), Expect = e-170
Identities = 407/941 (43%), Positives = 515/941 (54%), Gaps = 133/941 (14%)
Query: 46 PTAHSTLPAPC----------HNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTR 95
P AH P + L+ +P + P +G GP FLS+ +
Sbjct: 26 PNAHKVASPPSGPAYPDDVLDYGLKPYSPLASLSGEPPGRFGEPDRVGPQK-FLSAA--K 82
Query: 96 PDGAPALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTA-------TLSLPS 148
P GA L SPRIEIT H Q + + D ++ P TL +P
Sbjct: 83 PAGASGL-SPRIEITPS----HELIQAVGPLRMRDAGLLVEQPPLAGVAASPRFTLPVPG 137
Query: 149 LEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPEEGF 208
E YR+P CLSPASS SS S + S SP+ SPCVSP P++
Sbjct: 138 FEGYREPLCLSPASSGSSAS---------------FISDTFSPYTSPCVSPNNGGPDDLC 182
Query: 209 PRGLGACTLLGSPRHSPSTSPRASVTEESWLGARS------SRPASPCNKRKYS----LN 258
P+ SPR SP SPR S+ E+S LG S SR +SP KR++S L
Sbjct: 183 PQFQNIPAHY-SPRTSPIMSPRTSLAEDSCLGRHSPVPRPASRSSSPGAKRRHSCAEALV 241
Query: 259 GRQPPYSPHHSPTPSPHGSPRVSVTDD-SWLGNTTQYTSSAIVAAINALTTDSSLDLGDG 317
P SP S +PSP S V+ D S G S+ I+ A+N+L TDS G
Sbjct: 242 ALPPGASPQRSRSPSPQPSSHVAPQDHGSPAGYPPVAGSAVIMDALNSLATDSPC----G 297
Query: 318 VPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHI-------RKGGFC 370
+P K KT+ + P + + P A Y + + + R+
Sbjct: 298 IPPKMWKTSPDPSP------------VSAAPSKAGLPRHIYPAVEFLGPCEQGERRNSAP 345
Query: 371 DQYLAVPQHPYQWAKPKPLSP-----TSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHH 425
+ L VP W PKPL P + ++ +LP L+W L S SG YELRIEVQPK HH
Sbjct: 346 ESILLVPP---TW--PKPLVPAIPICSIPVTASLPPLEWPLSSQSGSYELRIEVQPKPHH 400
Query: 426 RAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRIT 485
RAHYETEGSRGAVKA GGHP+VQLHGY+EN+PL LQ+FIGTAD+R+L+PHAFYQVHRIT
Sbjct: 401 RAHYETEGSRGAVKAPTGGHPVVQLHGYMENKPLGLQIFIGTADERILKPHAFYQVHRIT 460
Query: 486 GKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNT 545
GKTV+TTS+E I+ NTKVLEIPL P+N+MRA IDCAGILKLRN+DIELRKGETDIGRKNT
Sbjct: 461 GKTVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDCAGILKLRNADIELRKGETDIGRKNT 520
Query: 546 RVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSG 605
RVRLVFRVH+P+ SGR +SLQ ASNPIECSQRSA ELP+VE+Q TDS V GG++M+L+G
Sbjct: 521 RVRLVFRVHIPESSGRIVSLQTASNPIECSQRSAHELPMVERQDTDSCLVYGGQQMILTG 580
Query: 606 HNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYV 665
NF +SKV+F EK DG +WEMEA D+D +PN L VEIP +RN+ I +PV V+FYV
Sbjct: 581 QNFTSESKVVFTEKTTDGQQIWEMEATVDKDKSQPNMLFVEIPEYRNKHIRTPVKVNFYV 640
Query: 666 CNGKRKRSQYQRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPP 725
NGKRKRSQ Q FTY P VP IKTEPTD+Y+P C P GL +PYY Q +
Sbjct: 641 INGKRKRSQPQHFTYHP--VPAIKTEPTDEYDPTLICSPTHGGLG--SQPYYPQHPMVAE 696
Query: 726 DPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAP 785
P SCLVA PC Q T + ++P + + + Y + S LG QPA A
Sbjct: 697 SP-SCLVATMAPCQQFRTGL-SSPDARYQQQNPAAVLYQRS-KSLSPSLLGYQQPALMAA 753
Query: 786 --AVQDVPRPVATHPGSPGQPPPALLPQQVSAPPSSSCPPGLEHSLCPSSPSPPLPPATQ 843
++ D R V H GS GQ L P +P + P + +S P Q
Sbjct: 754 PLSLADAHRSVLVHAGSQGQSSALLHP----SPTNQQASPVIHYS-----------PTNQ 798
Query: 844 EPTC--------LQPCSPACPPATGRPQHLPSTVRRDESPTAGPRLLPEVH-------ED 888
+ C + C P T RP P + + SP + P ++ + + ++
Sbjct: 799 QLRCGSHQEFQHIMYCENFA-PGTTRPGPPPVSQGQRLSPGSYPTVIQQQNATSQRAAKN 857
Query: 889 GSP-----NLAPIPVTVKREPEELDQLYLDDVNEIIRNDLS 924
G P + P VT+K+E + LDQ YLDD E+I LS
Sbjct: 858 GPPVSDQKEVLPAGVTIKQE-QNLDQTYLDD--ELIDTHLS 895
>gi|27886561 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 3 isoform 1 [Homo sapiens]
Length = 1075
Score = 559 bits (1440), Expect = e-159
Identities = 332/663 (50%), Positives = 420/663 (63%), Gaps = 59/663 (8%)
Query: 98 GAPALESPRIEITSCLGLYHNN-NQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPS 156
G E P I+ITS H + D+++ D PS L LP +YR+ S
Sbjct: 102 GPKPFECPSIQITSISPNCHQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRESS 161
Query: 157 CL-SPASSLSSRSCNSEASSYESNYSYPY----------------ASPQTSPWQSP--CV 197
SPASS+SSRS S+ASS ES S+ Y SP TSP SP C
Sbjct: 162 LSPSPASSISSRSWFSDASSCES-LSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCP 220
Query: 198 SPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGAR-----SSRPASPCNK 252
+T + G L SPR SP SPR+SVT+E+WL R SSRP SPC K
Sbjct: 221 GEETWHQQYGLGHSL-------SPRQSPCHSPRSSVTDENWLSPRPASGPSSRPTSPCGK 273
Query: 253 RKYSLNGRQPPY----SPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTT 308
R++S + Y SPHHSP PSP SPR SVT+D+WL N + + S + A+
Sbjct: 274 RRHS--SAEVCYAGSLSPHHSPVPSPGHSPRGSVTEDTWL-NASVHGGSGLGPAVFPFQY 330
Query: 309 DSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGG 368
D +P+K+RKT+ +Q + K+E +D GS P + + +D Q+ K
Sbjct: 331 CVETD----IPLKTRKTSEDQAAILPGKLELCSDDQGSLSPARETSIDDGLGSQYPLKKD 386
Query: 369 FC-DQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRA 427
C DQ+L+VP P+ W+KPKP + + +LP LDW LP+H G EL+IEVQPK+HHRA
Sbjct: 387 SCGDQFLSVPS-PFTWSKPKPGHTPIFRTSSLPPLDWPLPAHFGQCELKIEVQPKTHHRA 445
Query: 428 HYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGK 487
HYETEGSRGAVKAS GGHP+V+L GY E +P+ LQ+FIGTADDR LRPHAFYQVHRITGK
Sbjct: 446 HYETEGSRGAVKASTGGHPVVKLLGYNE-KPINLQMFIGTADDRYLRPHAFYQVHRITGK 504
Query: 488 TVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRV 547
TV+T S E I+++TKVLEIPLLPEN+M A IDCAGILKLRNSDIELRKGETDIGRKNTRV
Sbjct: 505 TVATASQEIIIASTKVLEIPLLPENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTRV 564
Query: 548 RLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHN 607
RLVFRVH+PQPSG+ LSLQ+AS P+ECSQRSAQELP +EK S +S V GG +MV++G N
Sbjct: 565 RLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMVVTGSN 624
Query: 608 FLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCN 667
FL +SK+IF+EK DG WE+E K R+ C+ +V+E+PP+ N +T+ V V FY+CN
Sbjct: 625 FLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCN 684
Query: 668 GKRKRSQYQRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDP 727
GKRK+SQ QRFTY P ++K E ++ + + S P+P P +Q+ P
Sbjct: 685 GKRKKSQSQRFTYTPV---LMKQEHREEIDLS------SVPSLPVPHPAQTQR---PSSD 732
Query: 728 SSC 730
S C
Sbjct: 733 SGC 735
Score = 40.0 bits (92), Expect = 0.010
Identities = 58/197 (29%), Positives = 69/197 (35%), Gaps = 48/197 (24%)
Query: 740 QRSTLMPAAPGVSPK-LHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHP 798
QRS P A ++ + L P Y G H G A A + P+A+ P
Sbjct: 891 QRSLSSPVADQITGQPSSQLQPITY-------GPSHSGSATTASPAAS-----HPLASSP 938
Query: 799 GSPGQPPPALLPQQVSAPPS---SSCPPGL-----EHSLCPSSPSPPLPPATQEPTCLQP 850
S G P P L P +P S SS P +HS S A C
Sbjct: 939 LS-GPPSPQLQPMPYQSPSSGTASSPSPATRMHSGQHSTQAQSTGQGGLSAPSSLICHSL 997
Query: 851 CSPACPPATGRPQHLPSTVRRDESPTAGPRLLPEVHEDGSPNLAPIPVTVKREPEELDQL 910
C PA P G +TV P ED PN A I L +
Sbjct: 998 CDPASFPPDG------ATVSIKPEP-----------EDREPNFATIG---------LQDI 1031
Query: 911 YLDDVNEIIRNDLSSTS 927
LDDVNEII D+S S
Sbjct: 1032 TLDDVNEIIGRDMSQIS 1048
>gi|27886559 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 3 isoform 4 [Homo sapiens]
Length = 1045
Score = 559 bits (1440), Expect = e-159
Identities = 332/663 (50%), Positives = 420/663 (63%), Gaps = 59/663 (8%)
Query: 98 GAPALESPRIEITSCLGLYHNN-NQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPS 156
G E P I+ITS H + D+++ D PS L LP +YR+ S
Sbjct: 102 GPKPFECPSIQITSISPNCHQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRESS 161
Query: 157 CL-SPASSLSSRSCNSEASSYESNYSYPY----------------ASPQTSPWQSP--CV 197
SPASS+SSRS S+ASS ES S+ Y SP TSP SP C
Sbjct: 162 LSPSPASSISSRSWFSDASSCES-LSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCP 220
Query: 198 SPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGAR-----SSRPASPCNK 252
+T + G L SPR SP SPR+SVT+E+WL R SSRP SPC K
Sbjct: 221 GEETWHQQYGLGHSL-------SPRQSPCHSPRSSVTDENWLSPRPASGPSSRPTSPCGK 273
Query: 253 RKYSLNGRQPPY----SPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTT 308
R++S + Y SPHHSP PSP SPR SVT+D+WL N + + S + A+
Sbjct: 274 RRHS--SAEVCYAGSLSPHHSPVPSPGHSPRGSVTEDTWL-NASVHGGSGLGPAVFPFQY 330
Query: 309 DSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGG 368
D +P+K+RKT+ +Q + K+E +D GS P + + +D Q+ K
Sbjct: 331 CVETD----IPLKTRKTSEDQAAILPGKLELCSDDQGSLSPARETSIDDGLGSQYPLKKD 386
Query: 369 FC-DQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRA 427
C DQ+L+VP P+ W+KPKP + + +LP LDW LP+H G EL+IEVQPK+HHRA
Sbjct: 387 SCGDQFLSVPS-PFTWSKPKPGHTPIFRTSSLPPLDWPLPAHFGQCELKIEVQPKTHHRA 445
Query: 428 HYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGK 487
HYETEGSRGAVKAS GGHP+V+L GY E +P+ LQ+FIGTADDR LRPHAFYQVHRITGK
Sbjct: 446 HYETEGSRGAVKASTGGHPVVKLLGYNE-KPINLQMFIGTADDRYLRPHAFYQVHRITGK 504
Query: 488 TVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRV 547
TV+T S E I+++TKVLEIPLLPEN+M A IDCAGILKLRNSDIELRKGETDIGRKNTRV
Sbjct: 505 TVATASQEIIIASTKVLEIPLLPENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTRV 564
Query: 548 RLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHN 607
RLVFRVH+PQPSG+ LSLQ+AS P+ECSQRSAQELP +EK S +S V GG +MV++G N
Sbjct: 565 RLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMVVTGSN 624
Query: 608 FLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCN 667
FL +SK+IF+EK DG WE+E K R+ C+ +V+E+PP+ N +T+ V V FY+CN
Sbjct: 625 FLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCN 684
Query: 668 GKRKRSQYQRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDP 727
GKRK+SQ QRFTY P ++K E ++ + + S P+P P +Q+ P
Sbjct: 685 GKRKKSQSQRFTYTPV---LMKQEHREEIDLS------SVPSLPVPHPAQTQR---PSSD 732
Query: 728 SSC 730
S C
Sbjct: 733 SGC 735
>gi|27886555 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 3 isoform 3 [Homo sapiens]
Length = 1065
Score = 559 bits (1440), Expect = e-159
Identities = 332/663 (50%), Positives = 420/663 (63%), Gaps = 59/663 (8%)
Query: 98 GAPALESPRIEITSCLGLYHNN-NQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPS 156
G E P I+ITS H + D+++ D PS L LP +YR+ S
Sbjct: 102 GPKPFECPSIQITSISPNCHQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRESS 161
Query: 157 CL-SPASSLSSRSCNSEASSYESNYSYPY----------------ASPQTSPWQSP--CV 197
SPASS+SSRS S+ASS ES S+ Y SP TSP SP C
Sbjct: 162 LSPSPASSISSRSWFSDASSCES-LSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCP 220
Query: 198 SPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGAR-----SSRPASPCNK 252
+T + G L SPR SP SPR+SVT+E+WL R SSRP SPC K
Sbjct: 221 GEETWHQQYGLGHSL-------SPRQSPCHSPRSSVTDENWLSPRPASGPSSRPTSPCGK 273
Query: 253 RKYSLNGRQPPY----SPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTT 308
R++S + Y SPHHSP PSP SPR SVT+D+WL N + + S + A+
Sbjct: 274 RRHS--SAEVCYAGSLSPHHSPVPSPGHSPRGSVTEDTWL-NASVHGGSGLGPAVFPFQY 330
Query: 309 DSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGG 368
D +P+K+RKT+ +Q + K+E +D GS P + + +D Q+ K
Sbjct: 331 CVETD----IPLKTRKTSEDQAAILPGKLELCSDDQGSLSPARETSIDDGLGSQYPLKKD 386
Query: 369 FC-DQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRA 427
C DQ+L+VP P+ W+KPKP + + +LP LDW LP+H G EL+IEVQPK+HHRA
Sbjct: 387 SCGDQFLSVPS-PFTWSKPKPGHTPIFRTSSLPPLDWPLPAHFGQCELKIEVQPKTHHRA 445
Query: 428 HYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGK 487
HYETEGSRGAVKAS GGHP+V+L GY E +P+ LQ+FIGTADDR LRPHAFYQVHRITGK
Sbjct: 446 HYETEGSRGAVKASTGGHPVVKLLGYNE-KPINLQMFIGTADDRYLRPHAFYQVHRITGK 504
Query: 488 TVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRV 547
TV+T S E I+++TKVLEIPLLPEN+M A IDCAGILKLRNSDIELRKGETDIGRKNTRV
Sbjct: 505 TVATASQEIIIASTKVLEIPLLPENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTRV 564
Query: 548 RLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHN 607
RLVFRVH+PQPSG+ LSLQ+AS P+ECSQRSAQELP +EK S +S V GG +MV++G N
Sbjct: 565 RLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMVVTGSN 624
Query: 608 FLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCN 667
FL +SK+IF+EK DG WE+E K R+ C+ +V+E+PP+ N +T+ V V FY+CN
Sbjct: 625 FLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCN 684
Query: 668 GKRKRSQYQRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDP 727
GKRK+SQ QRFTY P ++K E ++ + + S P+P P +Q+ P
Sbjct: 685 GKRKKSQSQRFTYTPV---LMKQEHREEIDLS------SVPSLPVPHPAQTQR---PSSD 732
Query: 728 SSC 730
S C
Sbjct: 733 SGC 735
>gi|4758804 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 3 isoform 2 [Homo sapiens]
Length = 1068
Score = 559 bits (1440), Expect = e-159
Identities = 332/663 (50%), Positives = 420/663 (63%), Gaps = 59/663 (8%)
Query: 98 GAPALESPRIEITSCLGLYHNN-NQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPS 156
G E P I+ITS H + D+++ D PS L LP +YR+ S
Sbjct: 102 GPKPFECPSIQITSISPNCHQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRESS 161
Query: 157 CL-SPASSLSSRSCNSEASSYESNYSYPY----------------ASPQTSPWQSP--CV 197
SPASS+SSRS S+ASS ES S+ Y SP TSP SP C
Sbjct: 162 LSPSPASSISSRSWFSDASSCES-LSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCP 220
Query: 198 SPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGAR-----SSRPASPCNK 252
+T + G L SPR SP SPR+SVT+E+WL R SSRP SPC K
Sbjct: 221 GEETWHQQYGLGHSL-------SPRQSPCHSPRSSVTDENWLSPRPASGPSSRPTSPCGK 273
Query: 253 RKYSLNGRQPPY----SPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTT 308
R++S + Y SPHHSP PSP SPR SVT+D+WL N + + S + A+
Sbjct: 274 RRHS--SAEVCYAGSLSPHHSPVPSPGHSPRGSVTEDTWL-NASVHGGSGLGPAVFPFQY 330
Query: 309 DSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGG 368
D +P+K+RKT+ +Q + K+E +D GS P + + +D Q+ K
Sbjct: 331 CVETD----IPLKTRKTSEDQAAILPGKLELCSDDQGSLSPARETSIDDGLGSQYPLKKD 386
Query: 369 FC-DQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRA 427
C DQ+L+VP P+ W+KPKP + + +LP LDW LP+H G EL+IEVQPK+HHRA
Sbjct: 387 SCGDQFLSVPS-PFTWSKPKPGHTPIFRTSSLPPLDWPLPAHFGQCELKIEVQPKTHHRA 445
Query: 428 HYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGK 487
HYETEGSRGAVKAS GGHP+V+L GY E +P+ LQ+FIGTADDR LRPHAFYQVHRITGK
Sbjct: 446 HYETEGSRGAVKASTGGHPVVKLLGYNE-KPINLQMFIGTADDRYLRPHAFYQVHRITGK 504
Query: 488 TVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRV 547
TV+T S E I+++TKVLEIPLLPEN+M A IDCAGILKLRNSDIELRKGETDIGRKNTRV
Sbjct: 505 TVATASQEIIIASTKVLEIPLLPENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTRV 564
Query: 548 RLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHN 607
RLVFRVH+PQPSG+ LSLQ+AS P+ECSQRSAQELP +EK S +S V GG +MV++G N
Sbjct: 565 RLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMVVTGSN 624
Query: 608 FLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCN 667
FL +SK+IF+EK DG WE+E K R+ C+ +V+E+PP+ N +T+ V V FY+CN
Sbjct: 625 FLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCN 684
Query: 668 GKRKRSQYQRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDP 727
GKRK+SQ QRFTY P ++K E ++ + + S P+P P +Q+ P
Sbjct: 685 GKRKKSQSQRFTYTPV---LMKQEHREEIDLS------SVPSLPVPHPAQTQR---PSSD 732
Query: 728 SSC 730
S C
Sbjct: 733 SGC 735
>gi|27886563 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 4 isoform 2 [Homo sapiens]
Length = 902
Score = 439 bits (1129), Expect = e-123
Identities = 358/947 (37%), Positives = 438/947 (46%), Gaps = 160/947 (16%)
Query: 25 AAAAPEHYGYASSNVS-PALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGG 83
A P YG A + P P P HS P P + P + GG
Sbjct: 47 ALGEPPPYGAAPIGIPRPPPPRPGMHSPPPRPAPS---------PGTWESQPARSVRLGG 97
Query: 84 PAGYFLSSGHTRPDGAPALESPRIEITSCL------GLYHNNNQFFHDVEVEDVLP---- 133
P G +G G LE P I ITS +N + D D P
Sbjct: 98 PGGGAGGAG-----GGRVLECPSIRITSISPTPEPPAALEDNPDAWGDGSPRDYPPPEGF 152
Query: 134 -----------SSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSY 182
+ SPS + SL S + D S A + SE + S +
Sbjct: 153 GGYREAGGQGGGAFFSPSPGSSSLSSWSFFSDASD-EAALYAACDEVESELNEAASRFGL 211
Query: 183 PYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWL--- 239
SP SP SP+ PE+ + +L G SP E+SWL
Sbjct: 212 G------SPLPSPRASPRPWTPEDPW-------SLYGP-------SPGGRGPEDSWLLLS 251
Query: 240 ----GARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPS-------PHGSPRVSVTDDSWL 288
S RPASPC KR+YS +G SP S S P P + + D
Sbjct: 252 APGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPPPPLPLARDPGS 311
Query: 289 GNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPP 348
Y + + +P K+R+T+ EQ ++ EP + G P
Sbjct: 312 PGPFDYVGAPPA---------------ESIPQKTRRTSSEQAVALPRSEEPASCN-GKLP 355
Query: 349 PPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPK-----PLSPTSYMSPTLPALD 403
A+ E + RK YLAVP P W+K + P+ TS LP LD
Sbjct: 356 LGAE---ESVAPPGGSRKEVAGMDYLAVPS-PLAWSKARIGGHSPIFRTS----ALPPLD 407
Query: 404 WQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQL 463
W LPS ELRIEVQP++HHRAHYETEGSRGAVKA+ GGHP+V+L GY E +PL LQ+
Sbjct: 408 WPLPSQYEQLELRIEVQPRAHHRAHYETEGSRGAVKAAPGGHPVVKLLGYSE-KPLTLQM 466
Query: 464 FIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGI 523
FIGTAD+R LRPHAFYQVHRITGK V+T S+EA++S TKVLE+ LLPEN+M A IDCAGI
Sbjct: 467 FIGTADERNLRPHAFYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAANIDCAGI 526
Query: 524 LKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELP 583
LKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQ G+ +S+Q AS PIECSQRSAQELP
Sbjct: 527 LKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQELP 586
Query: 584 LVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSL 643
VE S + V GG+++VL+G NFL DSKV+F+E+ PDG WE EA +R +L
Sbjct: 587 QVEAYSPSACSVRGGEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNEVTL 646
Query: 644 VVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYE----PA 699
+ +P + N+R++ PV V FYV NG+RKRS Q F +LP I K EP D P+
Sbjct: 647 TLTVPEYSNKRVSRPVQVYFYVSNGRRKRSPTQSFRFLPV---ICKEEPLPDSSLRGFPS 703
Query: 700 PTCGP--VSQGLSPLPRPYYSQQLAMPPDPSSCLVAGF-----PPCPQRSTLMPAAPGVS 752
+ P SP PY S P + L GF P PQ P
Sbjct: 704 ASATPFGTDMDFSPPRPPYPSYPHEDPACETPYLSEGFGYGMPPLYPQTG----PPPSYR 759
Query: 753 PKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHP----------GSPG 802
P L T G A P PAV +PRP + P G P
Sbjct: 760 PGLRMFPETRGTTGCAQP--------------PAVSFLPRPFPSDPYGGRGSSFSLGLPF 805
Query: 803 QPPPALLPQQVSAPPSSSCPPGLEHSLCPSSPSPPLPPATQEPTCLQPCSPACPPATGRP 862
PP P PP + PP LE S PLP P P G P
Sbjct: 806 SPPAPFRP-----PPLPASPP-LEGPFPSQSDVHPLPAEGYNKV-----GPGYGPGEGAP 854
Query: 863 QHLP-----STVRRDESPTAGPRLLPEVHEDGSPNLAPIPVTVKREP 904
+ S+ RD P G L EV E +L+ P EP
Sbjct: 855 EQEKSRGGYSSGFRDSVPIQG-ITLEEVSEIIGRDLSGFPAPPGEEP 900
Score = 30.4 bits (67), Expect = 8.0
Identities = 52/211 (24%), Positives = 74/211 (35%), Gaps = 55/211 (26%)
Query: 633 TDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTY-LPANVPIIKTE 691
TD D P PP+ + P + Y+ G F Y +P P +T
Sbjct: 711 TDMDFSPPR------PPYPSYPHEDPACETPYLSEG---------FGYGMPPLYP--QTG 753
Query: 692 PTDDYEPAPTCGPVSQG---------LSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRS 742
P Y P P ++G +S LPRP+ S S + PP P R
Sbjct: 754 PPPSYRPGLRMFPETRGTTGCAQPPAVSFLPRPFPSDPYGGRGSSFSLGLPFSPPAPFRP 813
Query: 743 TLMPAAP---GVSPKLHDLSPA---AYTKGVASPGHCH-LGLPQP----AGEAPAVQD-- 789
+PA+P G P D+ P Y K PG+ G P+ G + +D
Sbjct: 814 PPLPASPPLEGPFPSQSDVHPLPAEGYNK--VGPGYGPGEGAPEQEKSRGGYSSGFRDSV 871
Query: 790 -------------VPRPVATHPGSPGQPPPA 807
+ R ++ P PG+ PPA
Sbjct: 872 PIQGITLEEVSEIIGRDLSGFPAPPGEEPPA 902
>gi|209862845 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 4 isoform 1 [Homo sapiens]
Length = 964
Score = 436 bits (1121), Expect = e-122
Identities = 345/901 (38%), Positives = 422/901 (46%), Gaps = 154/901 (17%)
Query: 25 AAAAPEHYGYASSNVS-PALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGG 83
A P YG A + P P P HS P P + P + GG
Sbjct: 110 ALGEPPPYGAAPIGIPRPPPPRPGMHSPPPRPAPS---------PGTWESQPARSVRLGG 160
Query: 84 PAGYFLSSGHTRPDGAPALESPRIEITSCL------GLYHNNNQFFHDVEVEDVLP---- 133
P G +G G LE P I ITS +N + D D P
Sbjct: 161 PGGGAGGAG-----GGRVLECPSIRITSISPTPEPPAALEDNPDAWGDGSPRDYPPPEGF 215
Query: 134 -----------SSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSY 182
+ SPS + SL S + D S A + SE + S +
Sbjct: 216 GGYREAGGQGGGAFFSPSPGSSSLSSWSFFSDASD-EAALYAACDEVESELNEAASRFGL 274
Query: 183 PYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWL--- 239
SP SP SP+ PE+ + +L G SP E+SWL
Sbjct: 275 G------SPLPSPRASPRPWTPEDPW-------SLYGP-------SPGGRGPEDSWLLLS 314
Query: 240 ----GARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPS-------PHGSPRVSVTDDSWL 288
S RPASPC KR+YS +G SP S S P P + + D
Sbjct: 315 APGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPPPPLPLARDPGS 374
Query: 289 GNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPP 348
Y + + +P K+R+T+ EQ ++ EP + G P
Sbjct: 375 PGPFDYVGAPPA---------------ESIPQKTRRTSSEQAVALPRSEEPASCN-GKLP 418
Query: 349 PPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPK-----PLSPTSYMSPTLPALD 403
A+ E + RK YLAVP P W+K + P+ TS LP LD
Sbjct: 419 LGAE---ESVAPPGGSRKEVAGMDYLAVPS-PLAWSKARIGGHSPIFRTS----ALPPLD 470
Query: 404 WQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQL 463
W LPS ELRIEVQP++HHRAHYETEGSRGAVKA+ GGHP+V+L GY E +PL LQ+
Sbjct: 471 WPLPSQYEQLELRIEVQPRAHHRAHYETEGSRGAVKAAPGGHPVVKLLGYSE-KPLTLQM 529
Query: 464 FIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGI 523
FIGTAD+R LRPHAFYQVHRITGK V+T S+EA++S TKVLE+ LLPEN+M A IDCAGI
Sbjct: 530 FIGTADERNLRPHAFYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAANIDCAGI 589
Query: 524 LKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELP 583
LKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQ G+ +S+Q AS PIECSQRSAQELP
Sbjct: 590 LKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQELP 649
Query: 584 LVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSL 643
VE S + V GG+++VL+G NFL DSKV+F+E+ PDG WE EA +R +L
Sbjct: 650 QVEAYSPSACSVRGGEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNEVTL 709
Query: 644 VVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYE----PA 699
+ +P + N+R++ PV V FYV NG+RKRS Q F +LP I K EP D P+
Sbjct: 710 TLTVPEYSNKRVSRPVQVYFYVSNGRRKRSPTQSFRFLPV---ICKEEPLPDSSLRGFPS 766
Query: 700 PTCGP--VSQGLSPLPRPYYSQQLAMPPDPSSCLVAGF-----PPCPQRSTLMPAAPGVS 752
+ P SP PY S P + L GF P PQ P
Sbjct: 767 ASATPFGTDMDFSPPRPPYPSYPHEDPACETPYLSEGFGYGMPPLYPQTG----PPPSYR 822
Query: 753 PKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHP----------GSPG 802
P L T G A P PAV +PRP + P G P
Sbjct: 823 PGLRMFPETRGTTGCAQP--------------PAVSFLPRPFPSDPYGGRGSSFSLGLPF 868
Query: 803 QPPPALLPQQVSAPPSSSCPPGLEHSLCPSSPSPPLPPATQEPTCLQPCSPACPPATGRP 862
PP P PP + PP LE S PLP P P G P
Sbjct: 869 SPPAPFRP-----PPLPASPP-LEGPFPSQSDVHPLPAEGYNKV-----GPGYGPGEGAP 917
Query: 863 Q 863
+
Sbjct: 918 E 918
>gi|27886520 nuclear factor of activated T-cells 5 isoform a [Homo
sapiens]
Length = 1455
Score = 218 bits (556), Expect = 2e-56
Identities = 125/284 (44%), Positives = 175/284 (61%), Gaps = 8/284 (2%)
Query: 400 PALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVK-ASAGGHPIVQLHGYLENEP 458
P L Q P S EL+I VQP++ HRA Y TEGSRG+VK + G P V+L G+ NEP
Sbjct: 191 PMLCGQYPVKSEGKELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGH--NEP 248
Query: 459 LMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVI 518
++LQ+F+G R+ +PH FYQ R+TG+ +T E + T V+E+ L P N+M +
Sbjct: 249 VVLQVFVGNDSGRV-KPHGFYQACRVTGRN-TTPCKEVDIEGTTVIEVGLDPSNNMTLAV 306
Query: 519 DCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRS 578
DC GILKLRN+D+E R G +K+TR RLVFRV++ + G TL+LQ S+PI C+Q +
Sbjct: 307 DCVGILKLRNADVEARIGIAGSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPA 366
Query: 579 AQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLC 638
+P + K+S S V G +++ L G NFL+ +KVIF E D + W+ EA+ D +L
Sbjct: 367 G--VPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVSD-ENSWKSEAEIDMELF 423
Query: 639 KPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLP 682
N L+V++PP+ +Q IT PV V YV + Q FTY P
Sbjct: 424 HQNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTP 467
>gi|5729945 nuclear factor of activated T-cells 5 isoform c [Homo
sapiens]
Length = 1531
Score = 218 bits (556), Expect = 2e-56
Identities = 125/284 (44%), Positives = 175/284 (61%), Gaps = 8/284 (2%)
Query: 400 PALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVK-ASAGGHPIVQLHGYLENEP 458
P L Q P S EL+I VQP++ HRA Y TEGSRG+VK + G P V+L G+ NEP
Sbjct: 267 PMLCGQYPVKSEGKELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGH--NEP 324
Query: 459 LMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVI 518
++LQ+F+G R+ +PH FYQ R+TG+ +T E + T V+E+ L P N+M +
Sbjct: 325 VVLQVFVGNDSGRV-KPHGFYQACRVTGRN-TTPCKEVDIEGTTVIEVGLDPSNNMTLAV 382
Query: 519 DCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRS 578
DC GILKLRN+D+E R G +K+TR RLVFRV++ + G TL+LQ S+PI C+Q +
Sbjct: 383 DCVGILKLRNADVEARIGIAGSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPA 442
Query: 579 AQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLC 638
+P + K+S S V G +++ L G NFL+ +KVIF E D + W+ EA+ D +L
Sbjct: 443 G--VPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVSD-ENSWKSEAEIDMELF 499
Query: 639 KPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLP 682
N L+V++PP+ +Q IT PV V YV + Q FTY P
Sbjct: 500 HQNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTP 543
Score = 31.6 bits (70), Expect = 3.6
Identities = 47/205 (22%), Positives = 68/205 (33%), Gaps = 39/205 (19%)
Query: 34 YASSNVSPALP----LPTAHSTLPAPCHNLQTSTPGIIPPA----DHPSGYGAALDGGPA 85
Y+ +V LP LP + T A G PPA D S ++ GG
Sbjct: 22 YSRESVYDLLPKELQLPPSRETSVASMSQTSGGEAGSPPPAVVAADASSAPSSSSMGGAC 81
Query: 86 GYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHDVEV----------------- 128
F +S +S +++ SC +N+ + ++
Sbjct: 82 SSFTTSSSPTIYSTSVTDSKAMQVESCSSAVGVSNRGVSEKQLTSNTVQQHPSTPKRHTV 141
Query: 129 -------EDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYS 181
ED+L +S+ S L S + SC S N SSY N
Sbjct: 142 LYISPPPEDLLDNSRMSCQDEGCGLES-----EQSCSMWMEDSPSNFSNMSTSSYNDNTE 196
Query: 182 YPYASPQTSPWQSPCVSPKTTDPEE 206
P S + +P Q P V K D EE
Sbjct: 197 VPRKSRKRNPKQRPGV--KRRDCEE 219
>gi|164419746 nuclear factor of activated T-cells 5 isoform d [Homo
sapiens]
Length = 1548
Score = 218 bits (556), Expect = 2e-56
Identities = 125/284 (44%), Positives = 175/284 (61%), Gaps = 8/284 (2%)
Query: 400 PALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVK-ASAGGHPIVQLHGYLENEP 458
P L Q P S EL+I VQP++ HRA Y TEGSRG+VK + G P V+L G+ NEP
Sbjct: 285 PMLCGQYPVKSEGKELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGH--NEP 342
Query: 459 LMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVI 518
++LQ+F+G R+ +PH FYQ R+TG+ +T E + T V+E+ L P N+M +
Sbjct: 343 VVLQVFVGNDSGRV-KPHGFYQACRVTGRN-TTPCKEVDIEGTTVIEVGLDPSNNMTLAV 400
Query: 519 DCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRS 578
DC GILKLRN+D+E R G +K+TR RLVFRV++ + G TL+LQ S+PI C+Q +
Sbjct: 401 DCVGILKLRNADVEARIGIAGSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPA 460
Query: 579 AQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLC 638
+P + K+S S V G +++ L G NFL+ +KVIF E D + W+ EA+ D +L
Sbjct: 461 G--VPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVSD-ENSWKSEAEIDMELF 517
Query: 639 KPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLP 682
N L+V++PP+ +Q IT PV V YV + Q FTY P
Sbjct: 518 HQNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTP 561
Score = 31.2 bits (69), Expect = 4.7
Identities = 44/192 (22%), Positives = 63/192 (32%), Gaps = 35/192 (18%)
Query: 43 LPLPTAHSTLPAPCHNLQTSTPGIIPPA----DHPSGYGAALDGGPAGYFLSSGHTRPDG 98
L LP + T A G PPA D S ++ GG F +S
Sbjct: 53 LQLPPSRETSVASMSQTSGGEAGSPPPAVVAADASSAPSSSSMGGACSSFTTSSSPTIYS 112
Query: 99 APALESPRIEITSCLGLYHNNNQFFHDVEV------------------------EDVLPS 134
+S +++ SC +N+ + ++ ED+L +
Sbjct: 113 TSVTDSKAMQVESCSSAVGVSNRGVSEKQLTSNTVQQHPSTPKRHTVLYISPPPEDLLDN 172
Query: 135 SKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQS 194
S+ S L S + SC S N SSY N P S + +P Q
Sbjct: 173 SRMSCQDEGCGLES-----EQSCSMWMEDSPSNFSNMSTSSYNDNTEVPRKSRKRNPKQR 227
Query: 195 PCVSPKTTDPEE 206
P V K D EE
Sbjct: 228 PGV--KRRDCEE 237
>gi|164419744 nuclear factor of activated T-cells 5 isoform b [Homo
sapiens]
Length = 1549
Score = 218 bits (556), Expect = 2e-56
Identities = 125/284 (44%), Positives = 175/284 (61%), Gaps = 8/284 (2%)
Query: 400 PALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVK-ASAGGHPIVQLHGYLENEP 458
P L Q P S EL+I VQP++ HRA Y TEGSRG+VK + G P V+L G+ NEP
Sbjct: 285 PMLCGQYPVKSEGKELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGH--NEP 342
Query: 459 LMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVI 518
++LQ+F+G R+ +PH FYQ R+TG+ +T E + T V+E+ L P N+M +
Sbjct: 343 VVLQVFVGNDSGRV-KPHGFYQACRVTGRN-TTPCKEVDIEGTTVIEVGLDPSNNMTLAV 400
Query: 519 DCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRS 578
DC GILKLRN+D+E R G +K+TR RLVFRV++ + G TL+LQ S+PI C+Q +
Sbjct: 401 DCVGILKLRNADVEARIGIAGSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPA 460
Query: 579 AQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLC 638
+P + K+S S V G +++ L G NFL+ +KVIF E D + W+ EA+ D +L
Sbjct: 461 G--VPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVSD-ENSWKSEAEIDMELF 517
Query: 639 KPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLP 682
N L+V++PP+ +Q IT PV V YV + Q FTY P
Sbjct: 518 HQNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTP 561
Score = 31.2 bits (69), Expect = 4.7
Identities = 44/192 (22%), Positives = 63/192 (32%), Gaps = 35/192 (18%)
Query: 43 LPLPTAHSTLPAPCHNLQTSTPGIIPPA----DHPSGYGAALDGGPAGYFLSSGHTRPDG 98
L LP + T A G PPA D S ++ GG F +S
Sbjct: 53 LQLPPSRETSVASMSQTSGGEAGSPPPAVVAADASSAPSSSSMGGACSSFTTSSSPTIYS 112
Query: 99 APALESPRIEITSCLGLYHNNNQFFHDVEV------------------------EDVLPS 134
+S +++ SC +N+ + ++ ED+L +
Sbjct: 113 TSVTDSKAMQVESCSSAVGVSNRGVSEKQLTSNTVQQHPSTPKRHTVLYISPPPEDLLDN 172
Query: 135 SKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQS 194
S+ S L S + SC S N SSY N P S + +P Q
Sbjct: 173 SRMSCQDEGCGLES-----EQSCSMWMEDSPSNFSNMSTSSYNDNTEVPRKSRKRNPKQR 227
Query: 195 PCVSPKTTDPEE 206
P V K D EE
Sbjct: 228 PGV--KRRDCEE 237
>gi|27886524 nuclear factor of activated T-cells 5 isoform a [Homo
sapiens]
Length = 1455
Score = 218 bits (556), Expect = 2e-56
Identities = 125/284 (44%), Positives = 175/284 (61%), Gaps = 8/284 (2%)
Query: 400 PALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVK-ASAGGHPIVQLHGYLENEP 458
P L Q P S EL+I VQP++ HRA Y TEGSRG+VK + G P V+L G+ NEP
Sbjct: 191 PMLCGQYPVKSEGKELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGH--NEP 248
Query: 459 LMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVI 518
++LQ+F+G R+ +PH FYQ R+TG+ +T E + T V+E+ L P N+M +
Sbjct: 249 VVLQVFVGNDSGRV-KPHGFYQACRVTGRN-TTPCKEVDIEGTTVIEVGLDPSNNMTLAV 306
Query: 519 DCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRS 578
DC GILKLRN+D+E R G +K+TR RLVFRV++ + G TL+LQ S+PI C+Q +
Sbjct: 307 DCVGILKLRNADVEARIGIAGSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPA 366
Query: 579 AQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLC 638
+P + K+S S V G +++ L G NFL+ +KVIF E D + W+ EA+ D +L
Sbjct: 367 G--VPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVSD-ENSWKSEAEIDMELF 423
Query: 639 KPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLP 682
N L+V++PP+ +Q IT PV V YV + Q FTY P
Sbjct: 424 HQNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTP 467
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 70.9 bits (172), Expect = 5e-12
Identities = 80/308 (25%), Positives = 122/308 (39%), Gaps = 51/308 (16%)
Query: 625 HVWEMEAKTDRDLCKPNSLVVEIPP--FRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLP 682
H W + +D+C S + PP FRN + + C + K ++ +
Sbjct: 552 HRWRGGCEERKDVCI--STDDDCPPKTFRNVCVQTDRETFLKPCESESKTTRSNQLVPKK 609
Query: 683 ANVPII-KTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQR 741
N+ + + P +D++ + L P+ +QQ A+PP P+S + PP P
Sbjct: 610 LNISSLSQLSPPNDHKD------IHAALQPMEGMASNQQKALPPPPAS--IPPPPPLPSG 661
Query: 742 -STLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQP--AGEAPAVQDVPRPVATHP 798
+L PA P + P + + P LP P AG P P P + P
Sbjct: 662 LGSLSPAPP--------MPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAP 713
Query: 799 GSPGQPPPALLPQQVSAPPSSSCPPGLEHSLCPSSPSPPLPPATQEPTCLQPCSPACPPA 858
+PG PPPA P ++ PP PPGL L SS P PA + P+CP
Sbjct: 714 PNPGGPPPAPPPPGLAPPP----PPGLFFGLGSSSSQCPRKPAIE---------PSCPM- 759
Query: 859 TGRPQHLPSTVRRDESPTAGPRLLPEVHEDGSPNLAPIPVTVKREPEELDQLYLDDVNEI 918
+P + D S A P L + E P++ R+P E + L+ D +
Sbjct: 760 --KPLYWTRIQISDRSQNATPTLWDSLEE---PDI--------RDPSEFEYLFSKDTTQQ 806
Query: 919 IRNDLSST 926
+ LS T
Sbjct: 807 KKKPLSET 814
>gi|33286436 gametogenetin [Homo sapiens]
Length = 652
Score = 65.9 bits (159), Expect = 2e-10
Identities = 65/206 (31%), Positives = 84/206 (40%), Gaps = 26/206 (12%)
Query: 707 QGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSPAAYTKG 766
+G S P SQ A+PP P + FP + + A G P+ H A G
Sbjct: 320 EGCSGPPSAPASQARALPPPPYTT----FPGSKPKFDWVSAPDG--PERHFRFNGA-GGG 372
Query: 767 VASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPPPALL-------PQQVSAPPSS 819
+ +P L P G P P + + PG P +P PALL P + P
Sbjct: 373 IGAPRRRAAALSGPWGSPPPP---PEQIHSAPG-PRRPAPALLAPPTFIFPAPTNGEPMR 428
Query: 820 SCPPGLEHSLCPSSPSPPLPPATQEPTCLQPCS-PACPPATGRPQHLPSTVRRDESPTAG 878
PPGL+ P P P PP T +P LQP P PP T H S + +PTA
Sbjct: 429 PGPPGLQE--LPPLPPP-TPPPTLQPPALQPTPLPVAPPLTPGLGHKESAL----APTAA 481
Query: 879 PRLLPEVHEDGSPNLAPIPVTVKREP 904
P L P + D +P +P P EP
Sbjct: 482 PALPPALAADQAPAPSPAPAPTVAEP 507
Score = 39.7 bits (91), Expect = 0.013
Identities = 48/194 (24%), Positives = 71/194 (36%), Gaps = 17/194 (8%)
Query: 710 SPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPA-------APGVSPKLHDLSPAA 762
S LP MPP + V+ PP P TL+P A P++ L A+
Sbjct: 71 STLPLTLERPSPVMPPPEEAAAVSAPPPAP-AGTLLPGPSKWQKPAGTPVPRIRRLLEAS 129
Query: 763 YTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPPPALLPQQVSAPPSSSCP 822
+ +G P P P +V+D T P +P Q PP L + P S
Sbjct: 130 H-RGQGDPPSLRPLKPPPPPRQLSVKD------TVPRAPSQFPPPLETWKPPPPLPSERQ 182
Query: 823 PGLEHSLCPSSPSPPLPPATQEPTCLQPCSPACPPATGRPQHL-PSTVRRDESPTAGPRL 881
P + + P+ +P PP + A G P H + + +G L
Sbjct: 183 PA-DRRITPALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEMAQPADSESGLSL 241
Query: 882 LPEVHEDGSPNLAP 895
L ++ P+LAP
Sbjct: 242 LCKITFKSRPSLAP 255
Score = 39.7 bits (91), Expect = 0.013
Identities = 47/171 (27%), Positives = 61/171 (35%), Gaps = 31/171 (18%)
Query: 736 PPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVA 795
PP P++ P +P L L+P + + G P G P +Q++P
Sbjct: 391 PPPPEQIHSAPGPRRPAPAL--LAPPTFIFPAPTNGE-----PMRPGP-PGLQELP---- 438
Query: 796 THPGSPGQPPPALLPQQVSAPPSSSCPP---GLEHSLCPSSPS--PPLPPA--------- 841
P P PPP L P + P PP GL H +P+ P LPPA
Sbjct: 439 --PLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHKESALAPTAAPALPPALAADQAPAP 496
Query: 842 --TQEPTCLQPCSPACPPATGRPQHLPSTVRRDESPTA-GPRLLPEVHEDG 889
PT +P P PA T R S A G +H DG
Sbjct: 497 SPAPAPTVAEPSPPVSAPAPAAAPIKTRTRRNKGSRAARGATRKDGLHGDG 547
Score = 39.3 bits (90), Expect = 0.017
Identities = 42/149 (28%), Positives = 53/149 (35%), Gaps = 35/149 (23%)
Query: 710 SPLPRPYYSQQLAMPPDPSSCLVAG----FPPCPQRSTLMPAAPGVSPKLHDLSPAAYTK 765
SP P P P P+ L+A FP + P PG+ +L L P
Sbjct: 389 SPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQ-ELPPLPPPT--- 444
Query: 766 GVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQP--------------PPALLPQ 811
P P + PA+Q P PVA P +PG PPAL
Sbjct: 445 ------------PPPTLQPPALQPTPLPVAP-PLTPGLGHKESALAPTAAPALPPALAAD 491
Query: 812 QVSAPPSSSCPPGLEHSLCPSSPSPPLPP 840
Q AP + P E S S+P+P P
Sbjct: 492 QAPAPSPAPAPTVAEPSPPVSAPAPAAAP 520
>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
sapiens]
Length = 1636
Score = 65.1 bits (157), Expect = 3e-10
Identities = 72/228 (31%), Positives = 82/228 (35%), Gaps = 40/228 (17%)
Query: 692 PTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDP-----SSCLVAGFPPCPQRSTLMP 746
P P P C PV PLP PY A P P SS + AGFP
Sbjct: 899 PNPTPAPPPPCFPVPPP-QPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFP---------- 947
Query: 747 AAP--GVSPKLHDLSPAAYTKGVASPG------HCHLGLPQPAGEAPAVQDVPRPVATHP 798
AP G P+ H + G P H HL PQ G P P P A P
Sbjct: 948 -APRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQS--PYPYAPQP 1004
Query: 799 GSPGQPPPALLPQQVSAPPSSSCP--PGLEHSLCPSSPSPPLPPATQEPTCLQPCSPACP 856
G GQPPP L Q P P G P P PP PP P +P+
Sbjct: 1005 GVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPHPPLAYGP------APSTR 1058
Query: 857 PATGRPQHLPSTVRRDESPTAGPRLLPEVHEDGSPNLAPIPVTVKREP 904
P PQ P T+R P++ + P H SP +P P V P
Sbjct: 1059 PM--GPQAAPLTIR---GPSSAGQSTPSPHLVPSPAPSPGPGPVPPRP 1101
Score = 53.9 bits (128), Expect = 7e-07
Identities = 67/234 (28%), Positives = 84/234 (35%), Gaps = 39/234 (16%)
Query: 698 PAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHD 757
PAP GP Q P P+P+ SQ P P L P P APG+ P
Sbjct: 947 PAPRIGPQPQ---PHPQPHPSQAFG-PQPPQQPL-----PLQHPHLFPPQAPGLLPPQSP 997
Query: 758 LSPAAYTKGVAS-----------PGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPPP 806
P A GV PG LP +G P P P HP P P
Sbjct: 998 Y-PYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGP-PQPPHPPLAYGPAP 1055
Query: 807 ALLPQQVSAPP----------SSSCPPGLEHSLCPS---SPSPPLPPATQEPTCLQPCSP 853
+ P A P S+ P L S PS P PP PPA + P CL+ +
Sbjct: 1056 STRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPSPGPGPVPPRPPAAEPPPCLRRGAA 1115
Query: 854 ACPPATGRPQHLPSTVRRDESPTAGPRLLPEVHEDGSPNLAPIPV-TVKREPEE 906
A + P+ S +SP G LL D + P + ++R+P E
Sbjct: 1116 AADLLSSSPE---SQHGGTQSPGGGQPLLQPTKVDAAEGRRPQALRLIERDPYE 1166
Score = 43.5 bits (101), Expect = 0.001
Identities = 60/224 (26%), Positives = 78/224 (34%), Gaps = 33/224 (14%)
Query: 698 PAPTCGPVSQGLSPLPRPYYSQQLAMPPDPS------SCLVAGFPPCPQRSTLMPAAPG- 750
P P PV+ G + P P Y+ +L + P S S G P P + L A P
Sbjct: 808 PGPHAMPVAPGPALYPAPAYTPELGLVPRSSPQHGVVSSPYVGVGPAPPVAGLPSAPPPQ 867
Query: 751 -VSPKL-HDLSPAAYT-KGVASPGHCHL--------GLPQPAGEAPAVQDVPRPVATHPG 799
P+L + PA T + +P H P P P Q +P P T+P
Sbjct: 868 FSGPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTPY-TYPA 926
Query: 800 SPGQPPPAL------LPQQVSAP-----PSSSCPPGLEHSLCPSSPSPPLPPATQEPTCL 848
QP PA +P AP P P + P P PLP Q P
Sbjct: 927 GAKQPIPAQHHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQQPLP--LQHPHLF 984
Query: 849 QPCSPA-CPPATGRPQHLPSTVRRDESPTAGPRLLPEVHEDGSP 891
P +P PP + P V P +L P +D P
Sbjct: 985 PPQAPGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLP 1028
Score = 41.6 bits (96), Expect = 0.003
Identities = 56/212 (26%), Positives = 70/212 (33%), Gaps = 27/212 (12%)
Query: 711 PLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDL---------SPA 761
P PRP + L + S + AG PP RS +P P+L D P
Sbjct: 716 PPPRPTAPKPLLPRREESEAVEAGDPPEELRS--LPPDMVAGPRLPDTFLGSATPLHFPP 773
Query: 762 AYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHP-GSPGQPPPALLPQQVSAP---- 816
+ PG +L P P G + +P A P P P PAL P P
Sbjct: 774 SPFPSSTGPGPHYLSGPLPPGTYSGPTQLIQPRAPGPHAMPVAPGPALYPAPAYTPELGL 833
Query: 817 -PSSSCPPGLEHS-LCPSSPSPPL-------PPATQEPTCLQPCSPACPPATGRPQHLPS 867
P SS G+ S P+PP+ PP P PA +PS
Sbjct: 834 VPRSSPQHGVVSSPYVGVGPAPPVAGLPSAPPPQFSGPELAMAVRPATTTVDSIQAPIPS 893
Query: 868 TVRRDESPTAGPRLLPEVHEDGSPNLAPIPVT 899
+PT P P P P P T
Sbjct: 894 HTAPRPNPTPAPP--PPCFPVPPPQPLPTPYT 923
Score = 37.0 bits (84), Expect = 0.085
Identities = 28/64 (43%), Positives = 34/64 (53%), Gaps = 8/64 (12%)
Query: 793 PVATHPGSPGQPP---PALLPQQVSAPPSSSCPPGLEHSLCPSSPSP-PLPPATQEPTCL 848
PVA+ PG P +PP PA LP+ S P SS PP L L P +P P PP + P+
Sbjct: 1516 PVASLPG-PAEPPGLPPASLPE--STPIPSSSPPPLSSPL-PEAPQPKEEPPVPEAPSSG 1571
Query: 849 QPCS 852
P S
Sbjct: 1572 PPSS 1575
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 64.7 bits (156), Expect = 4e-10
Identities = 65/202 (32%), Positives = 79/202 (39%), Gaps = 11/202 (5%)
Query: 676 QRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQGLSPLPRP-YYSQQLAMPPDPSSCLVAG 734
Q T LP P P+ P+P P SQ + L P + +P P S L
Sbjct: 333 QLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATP 392
Query: 735 FPPCPQRSTLMP-AAPGVSPKLHDLSPAAYTKGVASPGHCHLGL---PQPAGEAPAVQDV 790
P P L P AP P LSP A T +P + L P +P VQ
Sbjct: 393 PPQAPPALALPPLQAPPSPPASPPLSPLA-TPSPQAPNALAVHLLQAPFSPPPSPPVQAP 451
Query: 791 PRPVATHPGSPGQPPPALLPQQVSAPPSSSCP-PGLEHSLCPSSPSPPL--PPATQEPTC 847
P A+ P SP PP+ P ++APP P P + PS+ PP PP P
Sbjct: 452 FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ 511
Query: 848 LQPCSPACPPATGRP--QHLPS 867
L P PPA P Q LPS
Sbjct: 512 LAKPPPQAPPALATPPLQALPS 533
Score = 60.8 bits (146), Expect = 6e-09
Identities = 65/213 (30%), Positives = 77/213 (36%), Gaps = 18/213 (8%)
Query: 700 PTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAG---FPPCPQRSTLMPAAPGVSPKLH 756
P PV SP P S P L A PP P PA+P +SP
Sbjct: 443 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP------PASPPMSPSAT 496
Query: 757 DLSPAAYTKGVASPGHCHLGLPQ--PAGEAPAVQDVPRPVATHPGSPGQPPPALLPQQVS 814
P A A P PQ PA P +Q +P P A+ PG P A LP
Sbjct: 497 P-PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 555
Query: 815 APPSSSCPPGLEHSLCPSSPSPPLPPATQEPTCLQPCSPACPPATGRPQHLPSTVRRDES 874
A P PP L L PSPP P Q P +P +P + P+ T+
Sbjct: 556 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR--RPPTPGPDTSVSGPR---LTLALAPG 610
Query: 875 PTAGPRLLPEVHEDGSPNLAPIPVTVKREPEEL 907
P P P G P+LA + PEEL
Sbjct: 611 PPPPPSRSPSSTLSG-PDLAGHSSSATSTPEEL 642
Score = 58.2 bits (139), Expect = 4e-08
Identities = 61/228 (26%), Positives = 81/228 (35%), Gaps = 18/228 (7%)
Query: 697 EPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTL--MPAAPGVSPK 754
+ AP GP+S P P + Q PP + + C + L P +P P
Sbjct: 291 DAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPS 350
Query: 755 LHDLS------PAAYTKGVASPG----HCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQP 804
L L P+ T + SP H L P + A P +A P
Sbjct: 351 LQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPS 410
Query: 805 PPALLPQQVSAPPSSSCPPGLEHSLCPSSPSPPLPPATQ---EPTCLQPCSP-ACPPATG 860
PPA P A PS P L L + SPP P Q P P SP A PP+
Sbjct: 411 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQA 470
Query: 861 RPQHLPSTVRRDESPTAGPRLLPEV--HEDGSPNLAPIPVTVKREPEE 906
P ++ SP A P + P P LA P+ + + P +
Sbjct: 471 PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ 518
Score = 50.8 bits (120), Expect = 6e-06
Identities = 113/489 (23%), Positives = 157/489 (32%), Gaps = 99/489 (20%)
Query: 20 RDEGAAAAAPEHYGYASSNVSPAL-PLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGA 78
+ +G A P + +PAL PL ++ P+P LQ+ P +P H S
Sbjct: 273 KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTC 332
Query: 79 ALDGGPAGYFLSSGHTRPDGAPALE-------SPRIEITSCLGLYHNNNQFFHDVEVEDV 131
L L P P+L+ +P + T+ LG Q H
Sbjct: 333 QL-----ATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLG--SPTLQATH-----SF 380
Query: 132 LPSSKRSP-------STATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPY 184
LPS SP + L+LP L+A P P S L++ S + + P+
Sbjct: 381 LPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF 440
Query: 185 ASPQTSPWQ-------SPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEES 237
+ P + P Q SP VSP T P + P L A L P SP SP S +
Sbjct: 441 SPPPSPPVQAPFSPPASPPVSPSATPPSQA-PPSLAAPPLQVPP--SPPASPPMSPSATP 497
Query: 238 WLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHG--SPRVSVTDDSWLGNTTQYT 295
A A P K PP +P TP SP S + +
Sbjct: 498 PPQAPPPLAAPPLQLAK------PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP 551
Query: 296 SSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQP--------------PSVALKVEPVG 341
S + + L P TL+ P P + L + P
Sbjct: 552 MSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP-- 609
Query: 342 EDLGSPPPP-------------------ADFAPEDYSSFQHIRKGGFC-----DQYLAVP 377
G PPPP A PE+ + +GG D LA
Sbjct: 610 ---GPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA- 665
Query: 378 QHPYQWAKPKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGA 437
HP W++ P P ++ L W + G + + YETEG A
Sbjct: 666 CHPAAWSR-GPAPPLAFRGAPGAPLPWPPATGPGSADGLCTI---------YETEGPESA 715
Query: 438 VKASAGGHP 446
A P
Sbjct: 716 TPAPGALDP 724
Score = 44.3 bits (103), Expect = 5e-04
Identities = 70/253 (27%), Positives = 99/253 (39%), Gaps = 51/253 (20%)
Query: 40 SPALPLPTAHSTLPAPCHNLQTSTPG---IIPPADHPSGYGAALDGGPAGYFLSSGHTRP 96
SPA P+A T AP H Q G + PP P AA GP SS P
Sbjct: 251 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS---SSPLATP 307
Query: 97 DGAPALES---PRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYR 153
+ AL+S P + T H+++ ++ LP + SPS PSL+
Sbjct: 308 SPSAALQSQAPPTLPATP-----HSSSL---TCQLATPLPLAPPSPSAP----PSLQTLP 355
Query: 154 DPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPR-GL 212
P PA+ S + + + + ++ +S+ SP +SP T P + P L
Sbjct: 356 SP----PATPPSQATTSLGSPTLQATHSF---------LPSPPLSPLATPPPQAPPALAL 402
Query: 213 GACTLLGSPRHSPSTSPRASVTEES-------WLGARSSRPASPCNKRKYSLNGRQPPYS 265
SP SP SP A+ + ++ L A S P SP Q P+S
Sbjct: 403 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP---------PVQAPFS 453
Query: 266 PHHSPTPSPHGSP 278
P SP SP +P
Sbjct: 454 PPASPPVSPSATP 466
Score = 38.1 bits (87), Expect = 0.038
Identities = 51/203 (25%), Positives = 70/203 (34%), Gaps = 41/203 (20%)
Query: 690 TEPTDDYEPAPTCG-----PVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTL 744
TEP+ P+ G P S+ LS P S + P + P P+ L
Sbjct: 218 TEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGL 277
Query: 745 MPAAPG-VSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQ 803
P V+P D +PA LG P+++ P +
Sbjct: 278 QALRPPQVTPPRKDAAPA-------------LG----------------PLSSSPLATPS 308
Query: 804 PPPALLPQQVSAPPSSSCPPGLEHSLCP-SSPSPPLPPATQEPTCLQ--PCSPACPPATG 860
P AL Q APP+ P C ++P P PP+ P LQ P PA PP+
Sbjct: 309 PSAAL---QSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQA 365
Query: 861 RPQHLPSTVRRDESPTAGPRLLP 883
T++ S P L P
Sbjct: 366 TTSLGSPTLQATHSFLPSPPLSP 388
Score = 35.4 bits (80), Expect = 0.25
Identities = 31/109 (28%), Positives = 42/109 (38%), Gaps = 17/109 (15%)
Query: 780 PAGEAPAVQDVPRPVATHPGSPGQPPPALLPQ---------QVSAPPSSSCPPGLEHSLC 830
PA AP + PRP PGSP +PPP + P V P + G+ +
Sbjct: 17 PAARAPGLL-TPRP----PGSP-RPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70
Query: 831 PSSPSPPLPPATQEPTCLQPCSPACPPATGRPQHLPSTVRRDESPTAGP 879
P S P + + P S PPA+GR + P P + P
Sbjct: 71 PESAPRAGPTRSAGTSSRNPASR--PPASGRGERAPPAKNTSPGPVSSP 117
Score = 33.5 bits (75), Expect = 0.94
Identities = 35/134 (26%), Positives = 48/134 (35%), Gaps = 16/134 (11%)
Query: 778 PQPAGEAPAVQDVPRPVATHPGSPGQPPPALLPQQVSAPPSSSCPPGLEHSLCPSSPSPP 837
P P +PA+ R T G P +P P+ P+ + P S EHS SP+
Sbjct: 167 PTPGTPSPAMARRSRAAGTEVGLP-RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAAR 225
Query: 838 LPPAT----QEPTCLQPCSPACP---PA--------TGRPQHLPSTVRRDESPTAGPRLL 882
P+ Q P S A P PA T R PS + P +
Sbjct: 226 RRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQV 285
Query: 883 PEVHEDGSPNLAPI 896
+D +P L P+
Sbjct: 286 TPPRKDAAPALGPL 299
Score = 31.6 bits (70), Expect = 3.6
Identities = 59/240 (24%), Positives = 81/240 (33%), Gaps = 52/240 (21%)
Query: 201 TTDPEEGFP------RGLGACTLLGSPRHSPSTSPR----------ASVTEESWLGARSS 244
T+ P G P R A T +G PR +PS PR +S +E S ++
Sbjct: 164 TSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHS-----TT 218
Query: 245 RPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAIN 304
P+ +R + G Q P S S + +P SP S + S +
Sbjct: 219 EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQ 278
Query: 305 AL----TTDSSLDLGDGVPVKSRKTTLEQPPSVALKVE------------PVGEDLGSPP 348
AL T D + S PS AL+ + + L +P
Sbjct: 279 ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPL 338
Query: 349 PPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLPS 408
P A +P S Q +P P A P + TS SPTL A LPS
Sbjct: 339 PLAPPSPSAPPSLQ------------TLPSPP---ATPPSQATTSLGSPTLQATHSFLPS 383
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 62.8 bits (151), Expect = 1e-09
Identities = 62/196 (31%), Positives = 77/196 (39%), Gaps = 11/196 (5%)
Query: 682 PANVPIIKTEPTDDYEPAPTCGPVSQGLSPLPRP-YYSQQLAMPPDPSSCLVAGFPPCPQ 740
P+ P P+ P+P P SQ + L P + +P P S L P P
Sbjct: 300 PSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPP 359
Query: 741 RSTLMP-AAPGVSPKLHDLSPAAYTKGVASPGHCHLGL---PQPAGEAPAVQDVPRPVAT 796
L P AP P LSP A T +P + L P +P VQ P A+
Sbjct: 360 ALALPPLQAPPSPPASPPLSPLA-TPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 418
Query: 797 HPGSPGQPPPALLPQQVSAPPSSSCP-PGLEHSLCPSSPSPPL--PPATQEPTCLQPCSP 853
P SP PP+ P ++APP P P + PS+ PP PP P L P
Sbjct: 419 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 478
Query: 854 ACPPATGRP--QHLPS 867
PPA P Q LPS
Sbjct: 479 QAPPALATPPLQALPS 494
Score = 60.8 bits (146), Expect = 6e-09
Identities = 65/213 (30%), Positives = 77/213 (36%), Gaps = 18/213 (8%)
Query: 700 PTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAG---FPPCPQRSTLMPAAPGVSPKLH 756
P PV SP P S P L A PP P PA+P +SP
Sbjct: 404 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP------PASPPMSPSAT 457
Query: 757 DLSPAAYTKGVASPGHCHLGLPQ--PAGEAPAVQDVPRPVATHPGSPGQPPPALLPQQVS 814
P A A P PQ PA P +Q +P P A+ PG P A LP
Sbjct: 458 P-PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 516
Query: 815 APPSSSCPPGLEHSLCPSSPSPPLPPATQEPTCLQPCSPACPPATGRPQHLPSTVRRDES 874
A P PP L L PSPP P Q P +P +P + P+ T+
Sbjct: 517 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR--RPPTPGPDTSVSGPR---LTLALAPG 571
Query: 875 PTAGPRLLPEVHEDGSPNLAPIPVTVKREPEEL 907
P P P G P+LA + PEEL
Sbjct: 572 PPPPPSRSPSSTLSG-PDLAGHSSSATSTPEEL 603
Score = 57.8 bits (138), Expect = 5e-08
Identities = 64/220 (29%), Positives = 80/220 (36%), Gaps = 32/220 (14%)
Query: 697 EPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLH 756
+ AP GP+S SPL P S PP PS+ PP Q PA P
Sbjct: 282 DAAPALGPLSS--SPLATPSPSA----PPSPSA------PPSLQTLPSPPATP------- 322
Query: 757 DLSPAAYTKGVASPG----HCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPPPALLPQQ 812
P+ T + SP H L P + A P +A P PPA P
Sbjct: 323 ---PSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLS 379
Query: 813 VSAPPSSSCPPGLEHSLCPSSPSPPLPPATQ---EPTCLQPCSP-ACPPATGRPQHLPST 868
A PS P L L + SPP P Q P P SP A PP+ P
Sbjct: 380 PLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPP 439
Query: 869 VRRDESPTAGPRLLPEV--HEDGSPNLAPIPVTVKREPEE 906
++ SP A P + P P LA P+ + + P +
Sbjct: 440 LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ 479
Score = 48.9 bits (115), Expect = 2e-05
Identities = 114/476 (23%), Positives = 151/476 (31%), Gaps = 101/476 (21%)
Query: 40 SPALPLPTAHSTLPAPCHNLQTSTPG---IIPPADHPSGYGAA-----LDGGPAGYFLSS 91
SPA P+A T AP H Q G + PP P AA L P S
Sbjct: 242 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS 301
Query: 92 GHTRPDGAPALE-------SPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSP----- 139
P P+L+ +P + T+ LG Q H LPS SP
Sbjct: 302 APPSPSAPPSLQTLPSPPATPPSQATTSLG--SPTLQATH-----SFLPSPPLSPLATPP 354
Query: 140 --STATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQ---- 193
+ L+LP L+A P P S L++ S + + P++ P + P Q
Sbjct: 355 PQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS 414
Query: 194 ---SPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPC 250
SP VSP T P + P L A L P SP SP S + A A P
Sbjct: 415 PPASPPVSPSATPPSQA-PPSLAAPPLQVPP--SPPASPPMSPSATPPPQAPPPLAAPPL 471
Query: 251 NKRKYSLNGRQPPYSPHHSPTPSPHG--SPRVSVTDDSWLGNTTQYTSSAIVAAINALTT 308
K PP +P TP SP S + + S +
Sbjct: 472 QLAK------PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP 525
Query: 309 DSSLDLGDGVPVKSRKTTLEQP--------------PSVALKVEPVGEDLGSPPPP---- 350
+ L P TL+ P P + L + P G PPPP
Sbjct: 526 VLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP-----GPPPPPSRSP 580
Query: 351 ---------------ADFAPEDYSSFQHIRKGGFC-----DQYLAVPQHPYQWAKPKPLS 390
A PE+ + +GG D LA HP W++ P
Sbjct: 581 SSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA-CHPAAWSR-GPAP 638
Query: 391 PTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHP 446
P ++ L W + G + + YETEG A A P
Sbjct: 639 PLAFRGAPGAPLPWPPATGPGSADGLCTI---------YETEGPESATPAPGALDP 685
Score = 43.5 bits (101), Expect = 0.001
Identities = 44/130 (33%), Positives = 51/130 (39%), Gaps = 35/130 (26%)
Query: 784 APAVQDVPRPVATHPGSPGQ--PP-----PALLP--------QQVSAPPSSSCPPGLEHS 828
APA P+P P Q PP PAL P SAPPS S PP L+
Sbjct: 256 APAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQ-- 313
Query: 829 LCPSSPSPPLPPATQEPTCL-----------QPCSPACPPATGRPQHLPS----TVRRDE 873
+ PSPP P +Q T L P P P AT PQ P+ ++
Sbjct: 314 ---TLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPP 370
Query: 874 SPTAGPRLLP 883
SP A P L P
Sbjct: 371 SPPASPPLSP 380
Score = 33.5 bits (75), Expect = 0.94
Identities = 35/134 (26%), Positives = 48/134 (35%), Gaps = 16/134 (11%)
Query: 778 PQPAGEAPAVQDVPRPVATHPGSPGQPPPALLPQQVSAPPSSSCPPGLEHSLCPSSPSPP 837
P P +PA+ R T G P +P P+ P+ + P S EHS SP+
Sbjct: 158 PTPGTPSPAMARRSRAAGTEVGLP-RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAAR 216
Query: 838 LPPAT----QEPTCLQPCSPACP---PA--------TGRPQHLPSTVRRDESPTAGPRLL 882
P+ Q P S A P PA T R PS + P +
Sbjct: 217 RRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQV 276
Query: 883 PEVHEDGSPNLAPI 896
+D +P L P+
Sbjct: 277 TPPRKDAAPALGPL 290
Score = 32.3 bits (72), Expect = 2.1
Identities = 30/109 (27%), Positives = 39/109 (35%), Gaps = 26/109 (23%)
Query: 780 PAGEAPAVQDVPRPVATHPGSPGQPPPALLPQQ---------VSAPPSSSCPPGLEHSLC 830
PA AP + PRP PGSP +PPP + P V P + G+ +
Sbjct: 17 PAARAPGLL-TPRP----PGSP-RPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70
Query: 831 PSSPSPPLPPATQEPTCLQPCSPACPPATGRPQHLPSTVRRDESPTAGP 879
P S P T P PA+GR + P P + P
Sbjct: 71 PESAPRAGPTRTSRP-----------PASGRGERAPPAKNTSPGPVSSP 108
>gi|223468681 v-rel reticuloendotheliosis viral oncogene homolog A
isoform 2 [Homo sapiens]
Length = 548
Score = 61.6 bits (148), Expect = 3e-09
Identities = 118/497 (23%), Positives = 179/497 (36%), Gaps = 78/497 (15%)
Query: 410 SGPYELRIEVQPKSHHRAHYETEG-SRGAVKASAGG-----HPIVQLHGYLENEPLMLQL 463
SGPY IE + R Y+ EG S G++ HP ++++GY + + L
Sbjct: 17 SGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTGPGTVRISL 76
Query: 464 FIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLE------IPLLPENSMRAV 517
D RPH H + GK +EA L + + I + + +
Sbjct: 77 ---VTKDPPHRPHP----HELVGKDCRDGFYEAELCPDRCIHSFQNLGIQCVKKRDLEQA 129
Query: 518 IDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQ-VASNPIECSQ 576
I I N E ++G+ D+ VRL F+V V PSGR L L V S+PI ++
Sbjct: 130 IS-QRIQTNNNPFQEEQRGDYDLNA----VRLCFQVTVRDPSGRPLRLPPVLSHPIFDNR 184
Query: 577 R-SAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAK-TD 634
+ EL + + G + +L +D +V F WE +
Sbjct: 185 APNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPG------WEARGSFSQ 238
Query: 635 RDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCN-GKRKRSQYQRFTYLPANVPIIKTE-- 691
D+ + ++V PP+ + + +PV VS + R+ S+ F YLP + E
Sbjct: 239 ADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEEK 298
Query: 692 -------------------PTDDYEPAPTCGPVSQGLS------PLPRPYYSQQLAMPPD 726
PTD P S+ + P P P+ S + D
Sbjct: 299 RKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYD 358
Query: 727 PSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPA 786
+V Q S L PA P V P+ +PA V++ +P A P
Sbjct: 359 EFPTMVFPSGQISQASALAPAPPQVLPQAP--APAPAPAMVSALAQAPAPVPVLAPGPPQ 416
Query: 787 VQDVPRPVATHPGSPGQPPPALLPQQ-----VSAPPSSSCPPGLEHSLCPSSPSP----- 836
P P T G G ALL Q + A +S P + L S
Sbjct: 417 AVAPPAPKPTQAGE-GTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLL 475
Query: 837 ----PLPPATQEPTCLQ 849
P+ P T EP ++
Sbjct: 476 NQGIPVAPHTTEPMLME 492
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 61.6 bits (148), Expect = 3e-09
Identities = 65/232 (28%), Positives = 88/232 (37%), Gaps = 18/232 (7%)
Query: 682 PANVPIIKTEPTDDYEPAPTCGP-VSQGLSPLPR---PYYSQQLAMPPDPSSCLVAGFPP 737
P+ P P P+P P +S +P P+ P + L +PP P + PP
Sbjct: 692 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPAS-----PP 746
Query: 738 CPQRSTLMPAAPGV--SPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVA 795
+T P P + +P L + P+ SP PA P +Q +P P A
Sbjct: 747 MSPSATPPPRVPPLLAAPPLQ-VPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPA 805
Query: 796 THPGSPGQPPPALLPQQVSAPPSSSCPPGLEHSLCPSSPSPPLPPATQEPTCLQPCSPAC 855
+ PG P A LP A P PP L L PSPP P Q P +P +P
Sbjct: 806 SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR--RPPTPGP 863
Query: 856 PPATGRPQHLPSTVRRDESPTAGPRLLPEVHEDGSPNLAPIPVTVKREPEEL 907
+ P+ T+ P P P G P+LA + PEEL
Sbjct: 864 DTSVSGPR---LTLALAPGPPPPPSRSPSSTLSG-PDLAGHSSSATSTPEEL 911
Score = 58.2 bits (139), Expect = 4e-08
Identities = 64/230 (27%), Positives = 87/230 (37%), Gaps = 26/230 (11%)
Query: 686 PIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFP-----PCPQ 740
P T P + P+ P+ +PL P+ L PP P+ C + P P P+
Sbjct: 527 PASLTTPPLENLPSLAPPPLQTASAPLTTPH----LETPPCPAPCPLQAPPSPLTTPPPE 582
Query: 741 RSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGS 800
+ + P +P P +G+ SP L P P +AP +P P+ P
Sbjct: 583 TPSSIATPPPQAPPALASPPL---QGLPSPPLSPLATPPP--QAPPXLALP-PLQAPPSP 636
Query: 801 PGQPPPALLPQQVSAPPSSSCPPGLEHSLCPSSPSPPLPPATQ---EPTCLQPCSP-ACP 856
P PP + L A PS P L L + SPP P Q P P SP A P
Sbjct: 637 PASPPLSPL-----ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP 691
Query: 857 PATGRPQHLPSTVRRDESPTAGPRLLPEV--HEDGSPNLAPIPVTVKREP 904
P+ P ++ SP A P + P P LA P+ V P
Sbjct: 692 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSP 741
Score = 56.2 bits (134), Expect = 1e-07
Identities = 73/237 (30%), Positives = 86/237 (36%), Gaps = 40/237 (16%)
Query: 699 APTCGPVSQGLSPL--PRPYYSQQLAM-------PPDPSSCLVAGFPPCPQRSTLMPAAP 749
AP P S LSPL P P LA+ P PS + A F P PA+P
Sbjct: 632 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP--------PASP 683
Query: 750 GVSPKLHDLSPAAYTKGV----------ASPGHCHLGLPQPAGE----APAVQDVPRPVA 795
VSP S A + ASP P P AP +Q P P A
Sbjct: 684 PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPA 743
Query: 796 THPGSPGQPPPALLPQQVSAPPSSSCPPGLEHSLCPS---SPSPPLPPATQEPTC-LQPC 851
+ P SP PP +P ++APP PP SL S P P PPA P P
Sbjct: 744 SPPMSPSATPPPRVPPLLAAPP-LQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPS 802
Query: 852 SPACPPAT---GRPQHLPSTVRRDESPTAGPRL-LPEVHEDGSPNLAPIPVTVKREP 904
PA P LP + P A P L P + SP +P +R P
Sbjct: 803 PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPP 859
Score = 55.8 bits (133), Expect = 2e-07
Identities = 54/205 (26%), Positives = 80/205 (39%), Gaps = 39/205 (19%)
Query: 697 EPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSC--LVAGFPPCPQRSTLMPAAPGVSPK 754
+ AP GP+S P P ++ +PP ++ L A PP P +T +P AP
Sbjct: 291 DAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAP----- 345
Query: 755 LHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPPPALLPQQVS 814
P P+ P++Q +P P AT P Q PP++ +
Sbjct: 346 -----------------------PSPSA-PPSLQTLPSPPAT---PPSQAPPSMTTPPMQ 378
Query: 815 APPSSSCPPGLE--HSLCPSSPSPPLPPATQEPTCLQ-PCSPACPPATGRPQHLPSTVRR 871
APPS P ++ HSL +SPS PP+ + LQ S P L + R+
Sbjct: 379 APPSLQTIPPIQVPHSL--TSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQ 436
Query: 872 DESPTAGPRLLPEVHEDGSPNLAPI 896
++ P D P AP+
Sbjct: 437 TQASLTSPSRPASTPPDSPPLQAPL 461
Score = 48.5 bits (114), Expect = 3e-05
Identities = 69/253 (27%), Positives = 84/253 (33%), Gaps = 54/253 (21%)
Query: 700 PTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMP--------AAPGV 751
P P+ LSP P S P S L + P P S +MP A P +
Sbjct: 464 PASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSL 523
Query: 752 SP-----------KLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGS 800
L L+P A HL P P +Q P P+ T P
Sbjct: 524 QTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCP-LQAPPSPLTTPPPE 582
Query: 801 --------PGQPPPALLPQQVSAPPSSSCP-PGLEHSLCPSSPSPP---LPP--ATQEPT 846
P Q PPAL ++PP P P L P +PP LPP A P
Sbjct: 583 TPSSIATPPPQAPPAL-----ASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPP 637
Query: 847 CLQPCSPACPPATGRPQHL------------PS-TVRRDESPTAGPRLLPEV--HEDGSP 891
P SP P+ P L PS V+ SP A P + P P
Sbjct: 638 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 697
Query: 892 NLAPIPVTVKREP 904
+LA P+ V P
Sbjct: 698 SLAAPPLQVPPSP 710
Score = 45.8 bits (107), Expect = 2e-04
Identities = 71/262 (27%), Positives = 91/262 (34%), Gaps = 66/262 (25%)
Query: 44 PLPTAH---STLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAP 100
PL T H PAPC +P PP + PS S P P
Sbjct: 552 PLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPS---------------SIATPPPQAPP 596
Query: 101 ALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSP-------STATLSLPSLEAYR 153
AL SP ++ LPS SP + L+LP L+A
Sbjct: 597 ALASPPLQ----------------------GLPSPPLSPLATPPPQAPPXLALPPLQAPP 634
Query: 154 DPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQ-------SPCVSPKTTDPEE 206
P P S L++ S + + P++ P + P Q SP VSP T P +
Sbjct: 635 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ 694
Query: 207 GFPRGLGACTLL--GSPRHSPSTSPRASVTEES-------WLGARSSRPASPCNKRKYSL 257
P L A L SP SP SP A+ ++ L S PASP +
Sbjct: 695 A-PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATP 753
Query: 258 NGRQPPY--SPHHSPTPSPHGS 277
R PP +P PSP S
Sbjct: 754 PPRVPPLLAAPPLQVPPSPPAS 775
Score = 37.0 bits (84), Expect = 0.085
Identities = 102/389 (26%), Positives = 136/389 (34%), Gaps = 80/389 (20%)
Query: 40 SPALPLPTAHSTLPAPCHNLQTSTPG---IIPPADHPSGYGAALDGGPAGYFLSS---GH 93
SPA P+A T AP H Q G + PP P AA GP LSS
Sbjct: 251 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP----LSSSPLAT 306
Query: 94 TRPDGAPALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYR 153
P G A P P + +P AT LP
Sbjct: 307 PSPSGTKARPVPP--------------------------PDNAATPLPAT--LPPSPPLA 338
Query: 154 DPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSP---------CVSPKTTDP 204
P L+P S + S + S + S S T P Q+P V T P
Sbjct: 339 TPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSP 398
Query: 205 EEGFP------RGLGACTLLGSP----RHSPST-SPR---ASVTEESWLGARSSRPASPC 250
P L A T LGSP HS T SPR AS+T S S+ P SP
Sbjct: 399 SLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPS--RPASTPPDSPP 456
Query: 251 NKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAI--NALTT 308
+ SL PP SP SP SP +++ L + ++ A ++++ L T
Sbjct: 457 LQAPLSLPA-SPPLQTSLSPAVSPLSSP-LTIHPLQALSSLASHSPQAPLSSLIMPPLET 514
Query: 309 DSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGG 368
SSL +L+ PP+ +L P+ PPP A ++ H+
Sbjct: 515 QSSL----------APPSLQTPPA-SLTTPPLENLPSLAPPPLQTASAPLTT-PHLETPP 562
Query: 369 FCDQYLAVPQHPYQWAKPKPLSPTSYMSP 397
C + P P P +P+S +P
Sbjct: 563 -CPAPCPLQAPPSPLTTPPPETPSSIATP 590
Score = 35.4 bits (80), Expect = 0.25
Identities = 31/109 (28%), Positives = 42/109 (38%), Gaps = 17/109 (15%)
Query: 780 PAGEAPAVQDVPRPVATHPGSPGQPPPALLPQ---------QVSAPPSSSCPPGLEHSLC 830
PA AP + PRP PGSP +PPP + P V P + G+ +
Sbjct: 17 PAARAPGLL-TPRP----PGSP-RPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70
Query: 831 PSSPSPPLPPATQEPTCLQPCSPACPPATGRPQHLPSTVRRDESPTAGP 879
P S P + + P S PPA+GR + P P + P
Sbjct: 71 PESAPRAGPTRSAGTSSRNPASR--PPASGRGERAPPAKNTSPGPVSSP 117
Score = 35.0 bits (79), Expect = 0.32
Identities = 48/163 (29%), Positives = 65/163 (39%), Gaps = 25/163 (15%)
Query: 132 LPSSKRSP---STATLSLPSLEAYRDPS---CLSPASSLSSRSCNSEASSYESNYSYP-- 183
LPS P ++A L+ P LE P+ +P S L++ + +S P
Sbjct: 538 LPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPA 597
Query: 184 YASPQTSPWQSPCVSPKTTDPEEGFPR-GLGACTLLGSPRHSPSTSPRASVTEES----- 237
ASP SP +SP T P + P L SP SP SP A+ + ++
Sbjct: 598 LASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALA 657
Query: 238 --WLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSP 278
L A S P SP Q P+SP SP SP +P
Sbjct: 658 VHLLQAPFSPPPSP---------PVQAPFSPPASPPVSPSATP 691
Score = 34.3 bits (77), Expect = 0.55
Identities = 40/158 (25%), Positives = 50/158 (31%), Gaps = 39/158 (24%)
Query: 778 PQPAGEAPAVQDVPRPVATHPGSPGQPPPALLPQQVSAPPSSSCPPGLEHSLCPSSP--- 834
P P +PA+ R T G P +P P+ P+ + P S EHS SP
Sbjct: 167 PTPGTPSPAMARRSRAAGTEVGLP-RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAAR 225
Query: 835 ---------------------SPPLPPATQEP----TCLQPCSPACPPATGRPQHLPSTV 869
+P PA P T P P+ P G P V
Sbjct: 226 RRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQV 285
Query: 870 ---RRDESPTAGPRLLPEVHEDGSPNLAPIPVTVKREP 904
R+D +P GP SP P P K P
Sbjct: 286 TPPRKDAAPALGPL-------SSSPLATPSPSGTKARP 316
Score = 30.8 bits (68), Expect = 6.1
Identities = 56/232 (24%), Positives = 76/232 (32%), Gaps = 45/232 (19%)
Query: 201 TTDPEEGFP------RGLGACTLLGSPRHSPSTSPR----------ASVTEESWLGARSS 244
T+ P G P R A T +G PR +PS PR +S +E S ++
Sbjct: 164 TSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHS-----TT 218
Query: 245 RPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAIN 304
P+ +R + G Q P S S + +P SP S + S +
Sbjct: 219 EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQ 278
Query: 305 ALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHI 364
AL P K L S L P PP D A +
Sbjct: 279 ALRPPQVTP-----PRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPA---- 329
Query: 365 RKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSP----TLPALDWQLPSHSGP 412
+P P A P PL+P S +P TLP+ PS + P
Sbjct: 330 ----------TLPPSP-PLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPP 370
>gi|223468676 v-rel reticuloendotheliosis viral oncogene homolog A
isoform 1 [Homo sapiens]
Length = 551
Score = 60.8 bits (146), Expect = 6e-09
Identities = 118/501 (23%), Positives = 182/501 (36%), Gaps = 83/501 (16%)
Query: 410 SGPYELRIEVQPKSHHRAHYETEG-SRGAVKASAGG-----HPIVQLHGYLENEPLMLQL 463
SGPY IE + R Y+ EG S G++ HP ++++GY + + L
Sbjct: 17 SGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTGPGTVRISL 76
Query: 464 FIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLE------IPLLPENSMRAV 517
D RPH H + GK +EA L + + I + + +
Sbjct: 77 ---VTKDPPHRPHP----HELVGKDCRDGFYEAELCPDRCIHSFQNLGIQCVKKRDLEQA 129
Query: 518 IDCAGILKLRNSD----IELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQ-VASNPI 572
I ++ N+ IE ++G+ D+ VRL F+V V PSGR L L V S+PI
Sbjct: 130 ISQR--IQTNNNPFQVPIEEQRGDYDLNA----VRLCFQVTVRDPSGRPLRLPPVLSHPI 183
Query: 573 ECSQR-SAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEA 631
++ + EL + + G + +L +D +V F WE
Sbjct: 184 FDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPG------WEARG 237
Query: 632 K-TDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCN-GKRKRSQYQRFTYLPANVPIIK 689
+ D+ + ++V PP+ + + +PV VS + R+ S+ F YLP +
Sbjct: 238 SFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHR 297
Query: 690 TE---------------------PTDDYEPAPTCGPVSQGLS------PLPRPYYSQQLA 722
E PTD P S+ + P P P+ S
Sbjct: 298 IEEKRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLST 357
Query: 723 MPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAG 782
+ D +V Q S L PA P V P+ +PA V++ +P A
Sbjct: 358 INYDEFPTMVFPSGQISQASALAPAPPQVLPQAP--APAPAPAMVSALAQAPAPVPVLAP 415
Query: 783 EAPAVQDVPRPVATHPGSPGQPPPALLPQQ-----VSAPPSSSCPPGLEHSLCPSSPSP- 836
P P P T G G ALL Q + A +S P + L S
Sbjct: 416 GPPQAVAPPAPKPTQAGE-GTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEF 474
Query: 837 --------PLPPATQEPTCLQ 849
P+ P T EP ++
Sbjct: 475 QQLLNQGIPVAPHTTEPMLME 495
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 60.5 bits (145), Expect = 7e-09
Identities = 59/221 (26%), Positives = 80/221 (36%), Gaps = 36/221 (16%)
Query: 681 LPANVPIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQ 740
+PA+V + P D PA PV++G P+ SQ P P P
Sbjct: 718 VPASVIVSAPPPAQDPAPAT---PVAKGAGLGPQAPDSQASPAPA----------PQIPA 764
Query: 741 RSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGS 800
+ L P SP L +P + + SP H +P +V P HP
Sbjct: 765 AAPLKGPGPSSSPSLPHQAPLGDSPHLPSP-HPTRPPSRPPSRPQSVSRPPSEPPLHPCP 823
Query: 801 PGQPPPAL-----LPQQVSAPPSSSCPPGLEHSLCPSSPSPPLPPATQEPTCLQPCSPAC 855
P Q PP L + Q+ PP +S P P P PPL P +Q P P +P
Sbjct: 824 PPQAPPTLPGIFVIQNQLGVPPPASNPA----PTAPGPPQPPLRPQSQPPEGPLPPAPHL 879
Query: 856 PPATGR-------------PQHLPSTVRRDESPTAGPRLLP 883
PP++ P PS + P+ GP P
Sbjct: 880 PPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSP 920
Score = 43.1 bits (100), Expect = 0.001
Identities = 57/202 (28%), Positives = 77/202 (38%), Gaps = 23/202 (11%)
Query: 687 IIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMP 746
I+ P +PA PVS LP +Q P P++ V P + M
Sbjct: 541 ILSAAPIQVGQPALFQMPVSLAAGSLP----TQSQPAPAGPAATTVLQGVTLPPSAVAML 596
Query: 747 AAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPPP 806
P + +PAA T G A+P + QPA +AP P P+ QPP
Sbjct: 597 NTP--DGLVQPATPAAAT-GEAAP----VLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQ 649
Query: 807 ALLPQQVSAPPSSSCP---PGLEHS---LCPSSPSPPLPPATQEPTCLQ---PCSPACPP 857
A P Q +APP ++ P PGL S + P P A LQ P + P
Sbjct: 650 APTP-QAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQP 708
Query: 858 ATGRPQHL--PSTVRRDESPTA 877
+ HL P++V P A
Sbjct: 709 LSAEGPHLSVPASVIVSAPPPA 730
Score = 37.7 bits (86), Expect = 0.050
Identities = 47/191 (24%), Positives = 65/191 (34%), Gaps = 30/191 (15%)
Query: 682 PANVPIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSS-CLVAGFPPCPQ 740
P +V +EP P P P G+ + QL +PP S+ A PP P
Sbjct: 807 PQSVSRPPSEPPLHPCPPPQAPPTLPGIFVI-----QNQLGVPPPASNPAPTAPGPPQPP 861
Query: 741 RSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGS 800
G P L P++ + VAS LP P P+ + P + P
Sbjct: 862 LRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPT---PSDFQLQFPPSQGPHK 918
Query: 801 PGQPPPAL--LPQQVSAPPSSSCPPGLEHSLCPSSPSPPLPPATQEPTCLQPCSPACPPA 858
PPP L +P+ P++P PP P Q T P P
Sbjct: 919 SPTPPPTLHLVPE-------------------PAAPPPPPPRTFQMVTTPFPALPQPKAL 959
Query: 859 TGRPQHLPSTV 869
R +PS +
Sbjct: 960 LERFHQVPSGI 970
Score = 35.0 bits (79), Expect = 0.32
Identities = 38/140 (27%), Positives = 48/140 (34%), Gaps = 23/140 (16%)
Query: 698 PAPTCGPVSQGLSPLPRPY-------YSQQLAMPPDPSSCLVA-----------GFPPCP 739
PAP V + S L R Y + L PP + A G PP
Sbjct: 1414 PAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAK 1473
Query: 740 QRSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPG 799
+R + P S T+ + S L L Q G PA P A G
Sbjct: 1474 RRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPS---YPHAASAG 1530
Query: 800 SPGQPPPALLPQQVSAPPSS 819
+P PPP P+ + PPSS
Sbjct: 1531 TPASPPPLHRPE--AYPPSS 1548
Score = 34.3 bits (77), Expect = 0.55
Identities = 48/179 (26%), Positives = 62/179 (34%), Gaps = 44/179 (24%)
Query: 687 IIKTEPTDDYEPAPTCG------PVSQG--LSPLPRPYYSQQLAMPPDPSSCLVAGFPPC 738
+ + T PAPT P SQG SP P P L + P+P A PP
Sbjct: 888 VASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPP----TLHLVPEP-----AAPPPP 938
Query: 739 PQRSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHP 798
P R+ M P PA LPQP VP +
Sbjct: 939 PPRTFQMVTTP---------FPA---------------LPQPKALLERFHQVPSGIILQN 974
Query: 799 ---GSPGQPPPALLPQQVSAPPSSSCPPGLEHSLCPSSPSPPLPPATQEPTCLQPCSPA 854
G+P P + +++P +S G S P++PS PA T L P PA
Sbjct: 975 KAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPA 1033
>gi|50345997 E1A binding protein p300 [Homo sapiens]
Length = 2414
Score = 60.1 bits (144), Expect = 9e-09
Identities = 67/219 (30%), Positives = 85/219 (38%), Gaps = 29/219 (13%)
Query: 703 GPVSQGLSPLPRPYYSQQLAMPPDPSSCLV-AGFPPCPQRSTLMPAAPG-----VSPKLH 756
G ++Q + P Y ++ P + L FP T +P AP VS
Sbjct: 737 GQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQM 796
Query: 757 DLSPAAYTKGVASPG----HCHLG-LPQPA----GEAPAVQDVPRPVATHPGSPGQPPPA 807
S + PG H H LPQPA +P P P T P Q PPA
Sbjct: 797 SSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPA 856
Query: 808 L-LPQQVSAPPSSSCPPGLE-HSLCPSSPSPPLPPATQEPTCLQPCSPACPPATGRPQHL 865
+P V PP+ PPG + +L P P PP TQ P +QP PA P A +PQ
Sbjct: 857 TTIPAPVPTPPAM--PPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSA-DQPQQQ 913
Query: 866 PSTVRRDESPTAGPRLLPEVHEDGSPNLAPIPVTVKREP 904
P R + TA V +P L P P T +P
Sbjct: 914 P----RSQQSTAA-----SVPTPTAPLLPPQPATPLSQP 943
Score = 43.9 bits (102), Expect = 7e-04
Identities = 60/259 (23%), Positives = 93/259 (35%), Gaps = 39/259 (15%)
Query: 686 PIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLM 745
P+ PT + P P+ G + +P P + AMPP P S + P R T
Sbjct: 834 PVPSRTPTPHHTP-PSIGAQQPPATTIPAPVPTPP-AMPPGPQSQALHP----PPRQTPT 887
Query: 746 PAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVAT----HPGSP 801
P + ++ PAA + QP + VP P A P +P
Sbjct: 888 PPTTQLPQQVQPSLPAAPSADQPQQ--------QPRSQQSTAASVPTPTAPLLPPQPATP 939
Query: 802 GQPPPALLPQQVSAPPSSSCPPGLEHSLCPSSPSPPLPPATQEPTCLQPCSPACPPATGR 861
P + QVS PPS+S ++ PS + + QP PA +
Sbjct: 940 LSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVD-QP-----EPADTQ 993
Query: 862 PQHLPSTVRRD------ESPTAGPRLLPEVHED------GSPNLAPIPVTVKR---EPEE 906
P+ + + D E+ L E+ E+ + +P P K+ +PEE
Sbjct: 994 PEDISESKVEDCKMESTETEERSTELKTEIKEEEDQPSTSATQSSPAPGQSKKKIFKPEE 1053
Query: 907 LDQLYLDDVNEIIRNDLSS 925
L Q + + + R D S
Sbjct: 1054 LRQALMPTLEALYRQDPES 1072
Score = 35.8 bits (81), Expect = 0.19
Identities = 25/80 (31%), Positives = 30/80 (37%), Gaps = 14/80 (17%)
Query: 780 PAGEAPAVQDVPRPVA-THPGSPGQPPPALLPQQVSAPPSSSCPPGLEHSLCPSSPSPPL 838
P G+ P P+P + P P PP L Q + P S G +PP
Sbjct: 1858 PTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAG--------QVTPPT 1909
Query: 839 PPATQEPTCLQPCSPACPPA 858
PP T QP P PPA
Sbjct: 1910 PPQT-----AQPPLPGPPPA 1924
Score = 31.6 bits (70), Expect = 3.6
Identities = 53/225 (23%), Positives = 73/225 (32%), Gaps = 48/225 (21%)
Query: 681 LPANVPIIKT-----EPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGF 735
LP+ P T +PT P PT P + +P Q A P
Sbjct: 1847 LPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVT 1906
Query: 736 PPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVA 795
PP P + T P PG P +++ H VQ RP+
Sbjct: 1907 PPTPPQ-TAQPPLPGPPPAAVEMAMQIQRAAETQRQMAH------------VQIFQRPI- 1952
Query: 796 THPGSPGQP--PPALLPQQVSAPPSSSCPPGLEHSLCPSSPSPPLPPATQEPTCLQPCSP 853
H P P P + P ++ PS PG+ PT +Q P
Sbjct: 1953 QHQMPPMTPMAPMGMNPPPMTRGPSGHLEPGM------------------GPTGMQQQPP 1994
Query: 854 ACPPATGRPQHLPSTVRRDESPTAGPRLLPEVHEDGSP-NLAPIP 897
+PQ L S + R P ++ V + G P N+AP P
Sbjct: 1995 WSQGGLPQPQQLQSGMPR-------PAMM-SVAQHGQPLNMAPQP 2031
Score = 30.8 bits (68), Expect = 6.1
Identities = 25/87 (28%), Positives = 31/87 (35%), Gaps = 16/87 (18%)
Query: 776 GLPQPAGEAPAVQDVPRPVATHPGSPGQPPPALLPQQVSAPPSSSCPPGLEHSLCPSSPS 835
GLP P P P P +P P P PQ P +S PP L +
Sbjct: 1846 GLPSPTPATPTT-----PTGQQPTTPQTPQPTSQPQPT---PPNSMPPYLPRTQAAG--- 1894
Query: 836 PPLPPATQEPTCLQPCSPACPPATGRP 862
P +Q Q +P PP T +P
Sbjct: 1895 ----PVSQGKAAGQ-VTPPTPPQTAQP 1916
Score = 30.4 bits (67), Expect = 8.0
Identities = 22/80 (27%), Positives = 29/80 (36%)
Query: 720 QLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQ 779
Q MPP + PP R PG+ P P G+ P G+P+
Sbjct: 1953 QHQMPPMTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPR 2012
Query: 780 PAGEAPAVQDVPRPVATHPG 799
PA + A P +A PG
Sbjct: 2013 PAMMSVAQHGQPLNMAPQPG 2032
>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
Length = 464
Score = 60.1 bits (144), Expect = 9e-09
Identities = 64/218 (29%), Positives = 83/218 (38%), Gaps = 16/218 (7%)
Query: 681 LPANVPIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQ 740
LPA P +K P P P+ + L P P L +PP P + PP P
Sbjct: 223 LPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPP----PGGLPLPPMPPTGPAPSGPPGPP 278
Query: 741 RSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGS 800
+ L P APGV P + P A +PG + P P PA P HP +
Sbjct: 279 Q--LPPPAPGVHPPAPVVHPPASGVHPPAPG---VHPPAPGVHPPAPGVHPPTSGVHPPA 333
Query: 801 PGQPPPALLPQQVSAPPSSSCPPGLEHSLCPSSPSPPLPPATQEPTCLQPCSPAC-PPAT 859
PG PPA P P P H P PP + + P +PA P A
Sbjct: 334 PGVHPPA--PGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAP 391
Query: 860 GRPQHLPSTVRRDESPTAGPRLLPEVHEDGSPNLAPIP 897
G H P+ ++P P+ P VH +P + P P
Sbjct: 392 G--VHPPAPGMHPQAPGVHPQ-PPGVH-PSAPGVHPQP 425
Score = 55.8 bits (133), Expect = 2e-07
Identities = 44/146 (30%), Positives = 61/146 (41%), Gaps = 21/146 (14%)
Query: 696 YEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKL 755
+ PAP P + G+ P + + P PS+ + PQ + PAAP V P+
Sbjct: 337 HPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVH------PQAPGVHPAAPAVHPQA 390
Query: 756 HDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDV-PRPVATHPGSPGQPPPALLPQQVS 814
+ P A +PG H PQP G P+ V P+P HP +PG PP +P +
Sbjct: 391 PGVHPPAPGMHPQAPG-VH---PQPPGVHPSAPGVHPQPPGVHPSNPGVHPPTPMPPMLR 446
Query: 815 APPSSSCPPGLEHSLCPSSPSPPLPP 840
P S P + PP PP
Sbjct: 447 PPLPSEGPGNI----------PPPPP 462
Score = 54.7 bits (130), Expect = 4e-07
Identities = 52/168 (30%), Positives = 68/168 (40%), Gaps = 19/168 (11%)
Query: 686 PIIKTEPTDDYEPAPTCGPVSQGLSP-LPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTL 744
P++ + + PAP P + G+ P P + PP P PP P +
Sbjct: 292 PVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPGV-----HPPAPG---V 343
Query: 745 MPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDV-PRPVATHPGSPGQ 803
P APGV P + P A GV P + PQ G PA V P+ HP +PG
Sbjct: 344 HPPAPGVHPPAPGVHPPA--PGVHPPPSAGVH-PQAPGVHPAAPAVHPQAPGVHPPAPGM 400
Query: 804 PP--PALLPQ----QVSAPPSSSCPPGLEHSLCPSSPSPPLPPATQEP 845
P P + PQ SAP PPG+ S P P+PP + P
Sbjct: 401 HPQAPGVHPQPPGVHPSAPGVHPQPPGVHPSNPGVHPPTPMPPMLRPP 448
Score = 33.9 bits (76), Expect = 0.72
Identities = 39/121 (32%), Positives = 46/121 (38%), Gaps = 18/121 (14%)
Query: 791 PRPVATHPGSPG--QPPPALLPQQVSAPP-SSSCPPGLEHSLCPSSPSPPLPPATQ---E 844
P P + G PG +PPP L+ PP S PP L P P PP PA
Sbjct: 218 PAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGL-PLPPMPPTGPAPSGPPG 276
Query: 845 PTCLQPCSPAC--------PPATGRPQHLPSTVRRDESPTAGPRLLPEVHEDGSPNLAPI 896
P L P +P PPA+G H P+ +P P P VH S P
Sbjct: 277 PPQLPPPAPGVHPPAPVVHPPASG--VHPPAPGVHPPAPGVHPP-APGVHPPTSGVHPPA 333
Query: 897 P 897
P
Sbjct: 334 P 334
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.131 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,881,259
Number of Sequences: 37866
Number of extensions: 3253900
Number of successful extensions: 23022
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 282
Number of HSP's successfully gapped in prelim test: 1340
Number of HSP's that attempted gapping in prelim test: 12995
Number of HSP's gapped (non-prelim): 7295
length of query: 930
length of database: 18,247,518
effective HSP length: 112
effective length of query: 818
effective length of database: 14,006,526
effective search space: 11457338268
effective search space used: 11457338268
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.