Search of human proteins with 27436993

Search of human proteins with 27436993

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|27436993 potassium voltage-gated channel, subfamily G,
member 3 isoform 2 [Homo sapiens]
         (425 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|27436993 potassium voltage-gated channel, subfamily G, member...   857   0.0  
gi|19071574 potassium voltage-gated channel, subfamily G, member...   849   0.0  
gi|6912444 potassium voltage-gated channel, subfamily G, member ...   333   1e-91
gi|27436996 potassium voltage-gated channel, subfamily G, member...   333   2e-91
gi|27436988 potassium voltage-gated channel, subfamily G, member...   330   2e-90
gi|27436974 potassium voltage-gated channel, Shab-related subfam...   306   2e-83
gi|4826784 potassium voltage-gated channel, Shab-related subfami...   300   2e-81
gi|7657289 potassium channel, subfamily V, member 1 [Homo sapiens]    270   2e-72
gi|45383011 potassium voltage-gated channel, delayed-rectifier, ...   260   2e-69
gi|25952108 potassium voltage-gated channel delayed-rectifier pr...   259   2e-69
gi|13492973 potassium voltage-gated channel delayed-rectifier pr...   253   2e-67
gi|20070166 potassium voltage-gated channel, subfamily F, member...   243   2e-64
gi|19424136 potassium channel, subfamily V, member 2 [Homo sapiens]   239   3e-63
gi|119395748 potassium voltage-gated channel subfamily A member ...   219   4e-57
gi|25952092 potassium voltage-gated channel, shaker-related subf...   217   2e-56
gi|4826786 Shaw-related voltage-gated potassium channel protein ...   214   9e-56
gi|163792201 Shaw-related voltage-gated potassium channel protei...   214   9e-56
gi|27436981 potassium voltage-gated channel, Shal-related subfam...   211   1e-54
gi|24497460 Shaw-related voltage-gated potassium channel protein...   210   2e-54
gi|88758576 Shaw-related voltage-gated potassium channel protein...   210   2e-54
gi|24497462 Shaw-related voltage-gated potassium channel protein...   210   2e-54
gi|24497464 Shaw-related voltage-gated potassium channel protein...   210   2e-54
gi|88758565 potassium voltage-gated channel, shaker-related subf...   209   3e-54
gi|5031819 potassium voltage-gated channel, shaker-related subfa...   208   9e-54
gi|9789987 potassium voltage-gated channel, Shal-related subfami...   207   1e-53
gi|4826782 potassium voltage-gated channel, shaker-related subfa...   207   2e-53
gi|21217561 Shaw-related voltage-gated potassium channel protein...   207   2e-53
gi|21217563 Shaw-related voltage-gated potassium channel protein...   207   2e-53
gi|24497458 Shaw-related voltage-gated potassium channel protein...   207   2e-53
gi|4504817 potassium voltage-gated channel, shaker-related subfa...   204   1e-52

>gi|27436993 potassium voltage-gated channel, subfamily G, member 3
           isoform 2 [Homo sapiens]
          Length = 425

 Score =  857 bits (2215), Expect = 0.0
 Identities = 425/425 (100%), Positives = 425/425 (100%)

Query: 1   MTFGRSGAASVVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNE 60
           MTFGRSGAASVVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNE
Sbjct: 1   MTFGRSGAASVVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNE 60

Query: 61  YFFDRHSEAFGFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRM 120
           YFFDRHSEAFGFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRM
Sbjct: 61  YFFDRHSEAFGFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRM 120

Query: 121 SDTYTFYSADEPGVLGRDEARPGGAEAAPSRRWLERMRRTFEEPTSSLAAQILASVSVVF 180
           SDTYTFYSADEPGVLGRDEARPGGAEAAPSRRWLERMRRTFEEPTSSLAAQILASVSVVF
Sbjct: 121 SDTYTFYSADEPGVLGRDEARPGGAEAAPSRRWLERMRRTFEEPTSSLAAQILASVSVVF 180

Query: 181 VIVSMVVLCASTLPDWRNAAADNRSLDDRSRIIEAICIGWFTAECIVRFIVSKNKCEFVK 240
           VIVSMVVLCASTLPDWRNAAADNRSLDDRSRIIEAICIGWFTAECIVRFIVSKNKCEFVK
Sbjct: 181 VIVSMVVLCASTLPDWRNAAADNRSLDDRSRIIEAICIGWFTAECIVRFIVSKNKCEFVK 240

Query: 241 RPLNIIDLLAITPYYISVLMTVFTGENSQLQRAGVTLRVLRMMRIFWVIKLARHFIGLQT 300
           RPLNIIDLLAITPYYISVLMTVFTGENSQLQRAGVTLRVLRMMRIFWVIKLARHFIGLQT
Sbjct: 241 RPLNIIDLLAITPYYISVLMTVFTGENSQLQRAGVTLRVLRMMRIFWVIKLARHFIGLQT 300

Query: 301 LGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKDFTSIPAACWWVIISM 360
           LGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKDFTSIPAACWWVIISM
Sbjct: 301 LGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKDFTSIPAACWWVIISM 360

Query: 361 TTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYHELKFRSARYSRSLS 420
           TTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYHELKFRSARYSRSLS
Sbjct: 361 TTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYHELKFRSARYSRSLS 420

Query: 421 TEFLN 425
           TEFLN
Sbjct: 421 TEFLN 425


>gi|19071574 potassium voltage-gated channel, subfamily G, member 3
           isoform 1 [Homo sapiens]
          Length = 436

 Score =  849 bits (2193), Expect = 0.0
 Identities = 425/436 (97%), Positives = 425/436 (97%), Gaps = 11/436 (2%)

Query: 1   MTFGRSGAASVVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNE 60
           MTFGRSGAASVVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNE
Sbjct: 1   MTFGRSGAASVVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNE 60

Query: 61  YFFDRHSEAFGFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRM 120
           YFFDRHSEAFGFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRM
Sbjct: 61  YFFDRHSEAFGFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRM 120

Query: 121 SDTYTFYSADEPGVLGRDEARPGGAEAAPSRRWLERMRRTFEEPTSSLAAQILASVSVVF 180
           SDTYTFYSADEPGVLGRDEARPGGAEAAPSRRWLERMRRTFEEPTSSLAAQILASVSVVF
Sbjct: 121 SDTYTFYSADEPGVLGRDEARPGGAEAAPSRRWLERMRRTFEEPTSSLAAQILASVSVVF 180

Query: 181 VIVSMVVLCASTLPDWRNAAADNRSLDDRSR-----------IIEAICIGWFTAECIVRF 229
           VIVSMVVLCASTLPDWRNAAADNRSLDDRSR           IIEAICIGWFTAECIVRF
Sbjct: 181 VIVSMVVLCASTLPDWRNAAADNRSLDDRSRYSAGPGREPSGIIEAICIGWFTAECIVRF 240

Query: 230 IVSKNKCEFVKRPLNIIDLLAITPYYISVLMTVFTGENSQLQRAGVTLRVLRMMRIFWVI 289
           IVSKNKCEFVKRPLNIIDLLAITPYYISVLMTVFTGENSQLQRAGVTLRVLRMMRIFWVI
Sbjct: 241 IVSKNKCEFVKRPLNIIDLLAITPYYISVLMTVFTGENSQLQRAGVTLRVLRMMRIFWVI 300

Query: 290 KLARHFIGLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKDFTSI 349
           KLARHFIGLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKDFTSI
Sbjct: 301 KLARHFIGLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKDFTSI 360

Query: 350 PAACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYHELK 409
           PAACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYHELK
Sbjct: 361 PAACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYHELK 420

Query: 410 FRSARYSRSLSTEFLN 425
           FRSARYSRSLSTEFLN
Sbjct: 421 FRSARYSRSLSTEFLN 436


>gi|6912444 potassium voltage-gated channel, subfamily G, member 2
           [Homo sapiens]
          Length = 466

 Score =  333 bits (855), Expect = 1e-91
 Identities = 180/425 (42%), Positives = 265/425 (62%), Gaps = 29/425 (6%)

Query: 4   GRSGAASVVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFF 63
           G + A  V++NVGG R  L+   L   PL R+ RL  CR   D+L VCDDYD  R+E+FF
Sbjct: 12  GGTRARHVIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVCDDYDVSRDEFFF 71

Query: 64  DRHSEAFGFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRMSDT 123
           DR   AF  I+  +R  GKLR     C L+F +E+ YWG++ A LE CC RRL  R    
Sbjct: 72  DRSPCAFRAIVALLRA-GKLRLLRGPCALAFRDELAYWGIDEARLERCCLRRLRRR---- 126

Query: 124 YTFYSADEPGVLGRDEARPGGAEAAPSR---------RWLERMRRTFEEPTSSLAAQILA 174
                 +E     R      GA+ +P+R         R   R+R   + P S LA ++ A
Sbjct: 127 ------EEEAAEARAGPTERGAQGSPARALGPRGRLQRGRRRLRDVVDNPHSGLAGKLFA 180

Query: 175 SVSVVFVIVSMVVLCASTLPDWRNAAADNRSLDDRSR---IIEAICIGWFTAECIVRFIV 231
            VSV FV V+ V LC ST+PD R A  +      + R   ++E +C+ WF+ E ++R + 
Sbjct: 181 CVSVSFVAVTAVGLCLSTMPDIR-AEEERGECSPKCRSLFVLETVCVAWFSFEFLLRSLQ 239

Query: 232 SKNKCEFVKRPLNIIDLLAITPYYISVLMTVFTGENSQ--LQRAGVTLRVLRMMRIFWVI 289
           +++KC F++ PLNIID+LA+ P+Y+S+L+ +  G      L+RAG+ LR+LR +R+ +V+
Sbjct: 240 AESKCAFLRAPLNIIDILALLPFYVSLLLGLAAGPGGTKLLERAGLVLRLLRALRVLYVM 299

Query: 290 KLARHFIGLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKDFTSI 349
           +LARH +GL++LGLT++RC RE  +LL+F+CVAMA+F+ L  L E  L    + +DF+S+
Sbjct: 300 RLARHSLGLRSLGLTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELG---ARRDFSSV 356

Query: 350 PAACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYHELK 409
           PA+ WW +ISMTTVGYGDM P ++PG+++    ++SGI+L+A P+T I+H+F + Y ELK
Sbjct: 357 PASYWWAVISMTTVGYGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELK 416

Query: 410 FRSAR 414
            +  R
Sbjct: 417 EQQQR 421


>gi|27436996 potassium voltage-gated channel, subfamily G, member 4
           [Homo sapiens]
          Length = 519

 Score =  333 bits (853), Expect = 2e-91
 Identities = 183/416 (43%), Positives = 261/416 (62%), Gaps = 28/416 (6%)

Query: 11  VVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRHSEAF 70
           +++NVGG RY L    L  FPL R+S+L  CRS  +++++CDDYD +  E+FFDR   AF
Sbjct: 61  ILINVGGRRYLLPWSTLDRFPLSRLSKLRLCRSYEEIVQLCDDYDEDSQEFFFDRSPSAF 120

Query: 71  GFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRMSDTYTFYSAD 130
           G I+ ++   GKL     MC LSF  E+ YWG+E AHLE CC R+L  ++ +        
Sbjct: 121 GVIVSFLAA-GKLVLLQEMCALSFQEELAYWGIEEAHLERCCLRKLLRKLEELEELAKLH 179

Query: 131 EPGVLG--RDEARPGGAEAAPSRRW---LERMRRTFEEPTSSLAAQILASVSVVFVIVSM 185
              VL   R+  RP    A+ S RW   + R+R   E P S L  ++ A +S++FV  + 
Sbjct: 180 REDVLRQQRETRRP----ASHSSRWGLCMNRLREMVENPQSGLPGKVFACLSILFVATTA 235

Query: 186 VVLCASTLPDWRNAAADNRSLDDRSR---IIEAICIGWFTAECIVRFIVSKNKCEFVKRP 242
           V LC ST+PD R A  D      +     I+E IC+ WF+ E  +RF+ +++KC+F + P
Sbjct: 236 VSLCVSTMPDLR-AEEDQGECSRKCYYIFIVETICVAWFSLEFCLRFVQAQDKCQFFQGP 294

Query: 243 LNIIDLLAITPYYISVLMTVFTGEN-------SQLQRAGVTLRVLRMMRIFWVIKLARHF 295
           LNIID+LAI+PYY+S+ ++    E+       S L++ G+ LRVLR +RI +V++LARH 
Sbjct: 295 LNIIDILAISPYYVSLAVSEEPPEDGERPSGSSYLEKVGLVLRVLRALRILYVMRLARHS 354

Query: 296 IGLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEH--GLDLETSNKDFTSIPAAC 353
           +GLQTLGLT++RC RE  +LL+F+ VA+ +FS L  + E   G  LE     FTSIPA+ 
Sbjct: 355 LGLQTLGLTVRRCTREFGLLLLFLAVAITLFSPLVYVAEKESGRVLE-----FTSIPASY 409

Query: 354 WWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYHELK 409
           WW IISMTTVGYGDM P +VPG+++    ++SGI+++A P T I+H+F   Y ELK
Sbjct: 410 WWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFSHSYLELK 465


>gi|27436988 potassium voltage-gated channel, subfamily G, member 1
           [Homo sapiens]
          Length = 513

 Score =  330 bits (845), Expect = 2e-90
 Identities = 176/417 (42%), Positives = 256/417 (61%), Gaps = 18/417 (4%)

Query: 11  VVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRHSEAF 70
           +++NVGG +YSL    L +FPL R+ +L  C +  D+L VCDDYD   NE+FFDR+  AF
Sbjct: 65  IIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILNVCDDYDVTCNEFFFDRNPGAF 124

Query: 71  GFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRMSDTYTFYSAD 130
           G IL ++R  GKLR    MC LSF  E++YWG+   HL+ CC+RR   ++ +       +
Sbjct: 125 GTILTFLRA-GKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEFAEMVERE 183

Query: 131 EPGVL----GRDEARPGGAEAAPSRRWLERMRRTFEEPTSSLAAQILASVSVVFVIVSMV 186
           E        GRD   P   E    R  + R+R   E P S L  ++ A +SV+FV V+ V
Sbjct: 184 EEDDALDSEGRDSEGPAEGEGRLGR-CMRRLRDMVERPHSGLPGKVFACLSVLFVTVTAV 242

Query: 187 VLCASTLPDWRNAAADNR--SLDDRSRIIEAICIGWFTAECIVRFIVSKNKCEFVKRPLN 244
            L  STLP  R          +     I+E++C+GWF+ E ++R I + +K  F++ PL 
Sbjct: 243 NLSVSTLPSLREEEEQGHCSQMCHNVFIVESVCVGWFSLEFLLRLIQAPSKFAFLRSPLT 302

Query: 245 IIDLLAITPYYISVLMTVFTGE-------NSQLQRAGVTLRVLRMMRIFWVIKLARHFIG 297
           +IDL+AI PYYI++L+             NS L + G+ LRVLR +RI +V++LARH +G
Sbjct: 303 LIDLVAILPYYITLLVDGAAAGRRKPGAGNSYLDKVGLVLRVLRALRILYVMRLARHSLG 362

Query: 298 LQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKDFTSIPAACWWVI 357
           LQTLGLT +RC RE  +LL+F+CVA+A+F+ L  ++E+ +     + +FTSIPA  WW +
Sbjct: 363 LQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEM---ADSPEFTSIPACYWWAV 419

Query: 358 ISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYHELKFRSAR 414
           I+MTTVGYGDM P + PG+++    ++SGI+L+A P+T I+H+F + Y ELK    R
Sbjct: 420 ITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLELKQEQER 476


>gi|27436974 potassium voltage-gated channel, Shab-related
           subfamily, member 2 [Homo sapiens]
          Length = 911

 Score =  306 bits (784), Expect = 2e-83
 Identities = 165/413 (39%), Positives = 244/413 (59%), Gaps = 9/413 (2%)

Query: 11  VVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRHSEAF 70
           V +NVGG  + +    L   P  R+ +L  C +   +LEVCDDY+   NEYFFDRH  AF
Sbjct: 37  VKINVGGLNHEVLWRTLDRLPRTRLGKLRDCNTHESLLEVCDDYNLNENEYFFDRHPGAF 96

Query: 71  GFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRMSDTYTFYSAD 130
             IL + R  GKL     MC LSF  E+ YWG++  +LE CCQ R   +  +        
Sbjct: 97  TSILNFYRT-GKLHMMEEMCALSFGQELDYWGIDEIYLESCCQARYHQK-KEQMNEELRR 154

Query: 131 EPGVLGRDEARPGGAEAAPSRRWLERMRRTFEEPTSSLAAQILASVSVVFVIVSMVVLCA 190
           E   +   E         P +R  +++    E+P SS+AA+ILA VS++F+++S + L  
Sbjct: 155 EAETMREREGEEFDNTCCPDKR--KKLWDLLEKPNSSVAAKILAIVSILFIVLSTIALSL 212

Query: 191 STLPDWRNAAADNRSLDDRSRI-IEAICIGWFTAECIVRFIVSKNKCEFVKRPLNIIDLL 249
           +TLP+ +      +  D+R    +EA+CI WFT E ++RF+ S NK +F K PLN+IDLL
Sbjct: 213 NTLPELQETDEFGQLNDNRQLAHVEAVCIAWFTMEYLLRFLSSPNKWKFFKGPLNVIDLL 272

Query: 250 AITPYYISVLMTVFTGENSQLQRAGVTLRVLRMMRIFWVIKLARHFIGLQTLGLTLKRCY 309
           AI PYY+++ +T       Q Q     +++ R+MRI  ++KLARH  GLQ+LG TL+R Y
Sbjct: 273 AILPYYVTIFLTESNKSVLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSY 332

Query: 310 REMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKDFTSIPAACWWVIISMTTVGYGDMY 369
            E+ +L++F+ + + IFS+L    E   D       FTSIPA+ WW  I+MTTVGYGD+Y
Sbjct: 333 NELGLLILFLAMGIMIFSSLVFFAEKDEDA----TKFTSIPASFWWATITMTTVGYGDIY 388

Query: 370 PITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYHELKFRSARYSRSLSTE 422
           P T+ G+I+GG+C ++G++++ALPI  I ++F + Y E K +     R  + E
Sbjct: 389 PKTLLGKIVGGLCCIAGVLVIALPIPIIVNNFSEFYKEQKRQEKAIKRREALE 441


>gi|4826784 potassium voltage-gated channel, Shab-related subfamily,
           member 1 [Homo sapiens]
          Length = 858

 Score =  300 bits (767), Expect = 2e-81
 Identities = 167/425 (39%), Positives = 247/425 (58%), Gaps = 11/425 (2%)

Query: 1   MTFGRSGAAS--VVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRER 58
           M   RS A S  V LNVGG  + +    L   P  R+ +L  C +   +LEVCDDY  + 
Sbjct: 21  MEIVRSKACSRRVRLNVGGLAHEVLWRTLDRLPRTRLGKLRDCNTHDSLLEVCDDYSLDD 80

Query: 59  NEYFFDRHSEAFGFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDD 118
           NEYFFDRH  AF  IL + R  G+L     MC LSF  E+ YWG++  +LE CCQ R   
Sbjct: 81  NEYFFDRHPGAFTSILNFYRT-GRLHMMEEMCALSFSQELDYWGIDEIYLESCCQARYHQ 139

Query: 119 RMSDTYTFYSADEPGVLGRDEARPGGAEAAPSRRWLERMRRTFEEPTSSLAAQILASVSV 178
           +          +   +  R+         A  R+ L  +    E+P SS+AA+ILA +S+
Sbjct: 140 KKEQMNEELKREAETLREREGEEFDNTCCAEKRKKLWDL---LEKPNSSVAAKILAIISI 196

Query: 179 VFVIVSMVVLCASTLPDWRNAAADNRSLDDRSRI-IEAICIGWFTAECIVRFIVSKNKCE 237
           +F+++S + L  +TLP+ ++     +S D+     +EA+CI WFT E ++RF+ S  K +
Sbjct: 197 MFIVLSTIALSLNTLPELQSLDEFGQSTDNPQLAHVEAVCIAWFTMEYLLRFLSSPKKWK 256

Query: 238 FVKRPLNIIDLLAITPYYISVLMTVFTGENSQLQRAGVTLRVLRMMRIFWVIKLARHFIG 297
           F K PLN IDLLAI PYY+++ +T       Q Q     +++ R+MRI  ++KLARH  G
Sbjct: 257 FFKGPLNAIDLLAILPYYVTIFLTESNKSVLQFQNVRRVVQIFRIMRILRILKLARHSTG 316

Query: 298 LQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKDFTSIPAACWWVI 357
           LQ+LG TL+R Y E+ +L++F+ + + IFS+L    E   D    +  F SIPA+ WW  
Sbjct: 317 LQSLGFTLRRSYNELGLLILFLAMGIMIFSSLVFFAEKDED----DTKFKSIPASFWWAT 372

Query: 358 ISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYHELKFRSARYSR 417
           I+MTTVGYGD+YP T+ G+I+GG+C ++G++++ALPI  I ++F + Y E K +     R
Sbjct: 373 ITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLVIALPIPIIVNNFSEFYKEQKRQEKAIKR 432

Query: 418 SLSTE 422
             + E
Sbjct: 433 REALE 437


>gi|7657289 potassium channel, subfamily V, member 1 [Homo sapiens]
          Length = 500

 Score =  270 bits (690), Expect = 2e-72
 Identities = 153/416 (36%), Positives = 243/416 (58%), Gaps = 30/416 (7%)

Query: 13  LNVGGARYSLSRELLKDFPLRRVSRLH----------GCRSERDVLEVCDDYDRERNEYF 62
           +NVGG+R+ LS++ L  FP  R+ +L              +    LE+CDD +   NEYF
Sbjct: 43  VNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVDNEYF 102

Query: 63  FDRHSEAFGFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDR--M 120
           FDR S+AF ++L Y R  G+L    ++C LSF  E+ YWG++   ++ CC+ R   R  +
Sbjct: 103 FDRSSQAFRYVLHYYRT-GRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKEL 161

Query: 121 SDTYTFYSADEPGVLGRDEARPGGAEAAPSRRWLERMRRTFEEPTSSLAAQILASVSVVF 180
           S+T  F    E      +  +       P+ R  +++    E+P SS AA+I   +S++F
Sbjct: 162 SETLDFKKDTEDQESQHESEQDFSQGPCPTVR--QKLWNILEKPGSSTAARIFGVISIIF 219

Query: 181 VIVSMVVLCASTLP-DWRNAAADNRSLDDRSRIIEAICIGWFTAECIVRFIVSKNKCEFV 239
           V+VS++ +   +    W     D + L+    I+E +CI WFT E ++RF+  +++C F+
Sbjct: 220 VVVSIINMALMSAELSW----LDLQLLE----ILEYVCISWFTGEFVLRFLCVRDRCRFL 271

Query: 240 KRPLNIIDLLAITPYYISVLMTVFTGENS--QLQRAGVTLRVLRMMRIFWVIKLARHFIG 297
           ++  NIIDLLAI P+YI++L+   +G  +  +L+  G  ++VLR++R   ++KL RH  G
Sbjct: 272 RKVPNIIDLLAILPFYITLLVESLSGSQTTQELENVGRIVQVLRLLRALRMLKLGRHSTG 331

Query: 298 LQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKDFTSIPAACWWVI 357
           L++LG+T+ +CY E+ +LL+F+ V ++IFS +    E  +   T    FTS+P A WW  
Sbjct: 332 LRSLGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQSIPDTT----FTSVPCAWWWAT 387

Query: 358 ISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYHELKFRSA 413
            SMTTVGYGD+ P T  G+I+  +C++SGI++LALPI  I   F  CY  LK + A
Sbjct: 388 TSMTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEA 443


>gi|45383011 potassium voltage-gated channel, delayed-rectifier,
           subfamily S, member 2 [Homo sapiens]
          Length = 477

 Score =  260 bits (664), Expect = 2e-69
 Identities = 143/412 (34%), Positives = 229/412 (55%), Gaps = 26/412 (6%)

Query: 13  LNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRHSEAFGF 72
           +NVGG +  L    L  FP  R+ RL  C S   +LE+CDDYD  + E++FDR+ E F +
Sbjct: 21  INVGGFKRRLRSHTLLRFPETRLGRLLLCHSREAILELCDDYDDVQREFYFDRNPELFPY 80

Query: 73  ILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCC------------QRRLDDRM 120
           +L +    GKL     +C  SF  E+ YWG+    ++ CC            Q + D++ 
Sbjct: 81  VLHFYHT-GKLHVMAELCVFSFSQEIEYWGINEFFIDSCCSYSYHGRKVEPEQEKWDEQS 139

Query: 121 SDTYTFYSADEPGVLGRDEARPGGAEAAPSRR--WLERMRRTFEEPTSSLAAQILASVSV 178
               T  S DE      D ++  G      RR  WL       + P  S+ +++ + +S+
Sbjct: 140 DQESTTSSFDEILAFYNDASKFDGQPLGNFRRQLWL-----ALDNPGYSVLSRVFSILSI 194

Query: 179 VFVIVSMVVLCASTLPDWRNAAAD-NRSLDDRSRIIEAICIGWFTAECIVRFIVSKNKCE 237
           + V+ S++ +C ++LPD++   +  N   D R  I+E   I WFT E + RF V+ +  +
Sbjct: 195 LVVMGSIITMCLNSLPDFQIPDSQGNPGEDPRFEIVEHFGIAWFTFELVARFAVAPDFLK 254

Query: 238 FVKRPLNIIDLLAITPYYISVLMTVFTGENSQLQRAGVTLRVLRMMRIFWVIKLARHFIG 297
           F K  LN+IDL++I P+YI++++ +       L   G   +VLR+MRIF ++KLARH  G
Sbjct: 255 FFKNALNLIDLMSIVPFYITLVVNLVVESTPTLANLGRVAQVLRLMRIFRILKLARHSTG 314

Query: 298 LQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKDFTSIPAACWWVI 357
           L++LG TLK  Y+E+ +LL+++ V ++IFS ++  +E     +  N+   +IPA  WW  
Sbjct: 315 LRSLGATLKYSYKEVGLLLLYLSVGISIFSVVAYTIE-----KEENEGLATIPACWWWAT 369

Query: 358 ISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYHELK 409
           +SMTTVGYGD+ P T  G++    C+++GI+++ LPIT I++ F   Y   K
Sbjct: 370 VSMTTVGYGDVVPGTTAGKLTASACILAGILVVVLPITLIFNKFSHFYRRQK 421


>gi|25952108 potassium voltage-gated channel delayed-rectifier
           protein S3 [Homo sapiens]
          Length = 491

 Score =  259 bits (663), Expect = 2e-69
 Identities = 140/413 (33%), Positives = 229/413 (55%), Gaps = 26/413 (6%)

Query: 11  VVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRHSEAF 70
           V LNVGG + S+ +  L  FP  R+ +L  C SE  +LE+CDDY     EY+FDR+   F
Sbjct: 17  VNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYYFDRNPSLF 76

Query: 71  GFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRMSDTY------ 124
            ++L +    GKL     +C  SF  E+ YWG+    ++ CC  R  +R  + +      
Sbjct: 77  RYVLNFYYT-GKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEENHEKDWDQ 135

Query: 125 ------TFYSADEPGVLGRDEARPGGAEAAPSRR--WLERMRRTFEEPTSSLAAQILASV 176
                 T  S +E  +  ++  +         R+  W+       E P   L+A+++A  
Sbjct: 136 KSHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIR-----MENPAYCLSAKLIAIS 190

Query: 177 SVVFVIVSMVVLCASTLPDWRNAAADNRSLDDRSRIIEAICIGWFTAECIVRFIVSKNKC 236
           S+  V+ S+V +C  ++ +++N   D    D     +E  CI WFT E  VR   +  + 
Sbjct: 191 SLSVVLASIVAMCVHSMSEFQNE--DGEVDDPVLEGVEIACIAWFTGELAVRLAAAPCQK 248

Query: 237 EFVKRPLNIIDLLAITPYYISVLMTVFTGENSQLQRAGVTLRVLRMMRIFWVIKLARHFI 296
           +F K PLNIID ++I P+Y ++ +     E+  ++  G  +++LR+MRIF ++KLARH +
Sbjct: 249 KFWKNPLNIIDFVSIIPFYATLAVDTKEEESEDIENMGKVVQILRLMRIFRILKLARHSV 308

Query: 297 GLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKDFTSIPAACWWV 356
           GL++LG TL+  Y E+ +LL+F+ V ++IFS    +L + ++ +      TSIP   WW 
Sbjct: 309 GLRSLGATLRHSYHEVGLLLLFLSVGISIFS----VLIYSVEKDDHTSSLTSIPICWWWA 364

Query: 357 IISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYHELK 409
            ISMTTVGYGD +P+T+ G+++   C++ GI+++ALPIT I++ F + Y + K
Sbjct: 365 TISMTTVGYGDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKYYQKQK 417


>gi|13492973 potassium voltage-gated channel delayed-rectifier
           protein S1 [Homo sapiens]
          Length = 526

 Score =  253 bits (646), Expect = 2e-67
 Identities = 158/438 (36%), Positives = 232/438 (52%), Gaps = 36/438 (8%)

Query: 13  LNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRHSEAFGF 72
           +NVGG R  LS   L  FP  R+ RL    SE     +CDDYD    E++FDRH   F  
Sbjct: 54  VNVGGVRRQLSARALARFPGTRLGRLQAAASEEQARRLCDDYDEAAREFYFDRHPGFFLS 113

Query: 73  ILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCC-----QRRLD-----DRMSD 122
           +L + R  G L     +C  +F  E  YWGL    L  CC     +RRL      D  SD
Sbjct: 114 LLHFYRT-GHLHVLDELCVFAFGQEADYWGLGENALAACCRARYLERRLTQPHAWDEDSD 172

Query: 123 TYTFYSA--DEPGVLGRDEARPGGAEAAPSRRWLERMRRTFEEPTSSLAAQILASVSVVF 180
           T +      DE   + R+ AR G A     RR   R+  T E P  SL +++ + VS+  
Sbjct: 173 TPSSVDPCPDEISDVQRELARYGAARCGRLRR---RLWLTMENPGYSLPSKLFSCVSISV 229

Query: 181 VIVSMVVLCASTLPDW--RNAAADNRSL-----------DDRSRIIEAICIGWFTAECIV 227
           V+ S+  +C  +LP++  R AAA   ++           D   R +E  CI WF+ E   
Sbjct: 230 VLASIAAMCIHSLPEYQAREAAAAVAAVAAGRSPEGVRDDPVLRRLEYFCIAWFSFEVSS 289

Query: 228 RFIVSKNKCEFVKRPLNIIDLLAITPYYISVLMTVFTGENS--QLQRAGVTLRVLRMMRI 285
           R +++ +   F   PLN+ID++++ P+Y+++L  V  G+    +    G  ++V R+MRI
Sbjct: 290 RLLLAPSTRNFFCHPLNLIDIVSVLPFYLTLLAGVALGDQGGKEFGHLGKVVQVFRLMRI 349

Query: 286 FWVIKLARHFIGLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKD 345
           F V+KLARH  GL++LG TLK  YRE+ +LL+++ V +++FS ++   E   D+      
Sbjct: 350 FRVLKLARHSTGLRSLGATLKHSYREVGILLLYLAVGVSVFSGVAYTAEKEEDV-----G 404

Query: 346 FTSIPAACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCY 405
           F +IPA  WW  +SMTTVGYGD+ P+TV G++    C++ GI+++ALPIT I++ F   Y
Sbjct: 405 FNTIPACWWWGTVSMTTVGYGDVVPVTVAGKLAASGCILGGILVVALPITIIFNKFSHFY 464

Query: 406 HELKFRSARYSRSLSTEF 423
              K   A    S   EF
Sbjct: 465 RRQKALEAAVRNSNHQEF 482


>gi|20070166 potassium voltage-gated channel, subfamily F, member 1
           [Homo sapiens]
          Length = 494

 Score =  243 bits (620), Expect = 2e-64
 Identities = 148/430 (34%), Positives = 237/430 (55%), Gaps = 20/430 (4%)

Query: 5   RSGAAS----VVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSER--DVLEVCDDYDRER 58
           +S AAS    +V+NVGG R  L  +LL  +P  R++ L  C +     +  +CDDYD  +
Sbjct: 15  QSSAASDDIEIVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCDDYDPGK 74

Query: 59  NEYFFDRHSEAFGFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDD 118
            E++FDR  +AF  ++  V   G++     +C + F NEM +W ++   L+ CC+  L +
Sbjct: 75  REFYFDRDPDAFKCVI-EVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCKSHLSE 133

Query: 119 RMSDTYTFYSADEPGVLGRDEARPGGAEAAPSRRWLERMRRTFEEPTSSLAAQILASVSV 178
           +  +        +   L  D+     AE    RR  + + +  E+P SS  A+++A +S 
Sbjct: 134 KREELEEIARRVQ---LILDDLGVDAAEGR-WRRCQKCVWKFLEKPESSCPARVVAVLSF 189

Query: 179 VFVIVSMVVLCASTLPDWRNAAAD-NRSLDDRSRIIEAICIGWFTAECIVRFIVSKNKCE 237
           + ++VS VV+C  T+P+ +   A+ NR        +E  CIGWFT E ++R   S NK  
Sbjct: 190 LLILVSSVVMCMGTIPELQVLDAEGNRVEHPTLENVETACIGWFTLEYLLRLFSSPNKLH 249

Query: 238 FVKRPLNIIDLLAITPYYISVLMTVFTGENSQLQRAGVTLRVLRMMRIFWVIKLARHFIG 297
           F    +NI+D+LAI P+Y+S+ +T       +L      ++ LR+MRI  + KLARH  G
Sbjct: 250 FALSFMNIVDVLAILPFYVSLTLTHLGARMMELTNVQQAVQALRIMRIARIFKLARHSSG 309

Query: 298 LQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKD--FTSIPAACWW 355
           LQTL   LKR ++E+ +LL+++ V + +FSAL      G  +E S+ +  F SIP + WW
Sbjct: 310 LQTLTYALKRSFKELGLLLMYLAVGIFVFSAL------GYTMEQSHPETLFKSIPQSFWW 363

Query: 356 VIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYHELKFRSARY 415
            II+MTTVGYGD+YP T  G++   +  + G++ +ALPI  I ++FV+ Y++ +      
Sbjct: 364 AIITMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRYYNKQRVLETAA 423

Query: 416 SRSLSTEFLN 425
              L    LN
Sbjct: 424 KHELELMELN 433


>gi|19424136 potassium channel, subfamily V, member 2 [Homo sapiens]
          Length = 545

 Score =  239 bits (610), Expect = 3e-63
 Identities = 148/417 (35%), Positives = 225/417 (53%), Gaps = 33/417 (7%)

Query: 13  LNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRHSEAFGF 72
           +NVGG  Y L    L  FP  R+ RL    S    L +CDDY+ + +EYFFDR    F  
Sbjct: 101 VNVGGHSYQLDYCELAGFPKTRLGRLATSTSRSRQLSLCDDYEEQTDEYFFDRDPAVFQL 160

Query: 73  ILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCC-----QRR--LDDRMSDTYT 125
           +  +    G L     +C   F  E+ YWG+   +   CC     +RR  L +R+   + 
Sbjct: 161 VYNFYLS-GVLLVLDGLCPRRFLEELGYWGVRLKYTPRCCRICFEERRDELSERLKIQHE 219

Query: 126 FYS---ADEPGVLGRDEARPGGAEAAPSRRWLERMRRTFEEPTSSLAAQILASVSVVFVI 182
             +    +E   L RD    G     P RR   R+    E+P SS+AA+ +   S  FV+
Sbjct: 220 LRAQAQVEEAEELFRDMRFYG-----PQRR---RLWNLMEKPFSSVAAKAIGVASSTFVL 271

Query: 183 VSMVVLCASTLPDWRNAAADNRSLDDRSRI---IEAICIGWFTAECIVRFIVSKNKCEFV 239
           VS+V L  +T+ + +  +       D   I   +E +C+G+FT E ++R   + +   F 
Sbjct: 272 VSVVALALNTVEEMQQHSGQGEGGPDLRPILEHVEMLCMGFFTLEYLLRLASTPDLRRFA 331

Query: 240 KRPLNIIDLLAITPYYISVLMTVFTGENSQ-------LQRAGVTLRVLRMMRIFWVIKLA 292
           +  LN++DL+AI P Y+ +L+  FTGE  Q       + + G  LRV+R+MRIF ++KLA
Sbjct: 332 RSALNLVDLVAILPLYLQLLLECFTGEGHQRGQTVGSVGKVGQVLRVMRLMRIFRILKLA 391

Query: 293 RHFIGLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKDFTSIPAA 352
           RH  GL+  G TL++CY+++  LL+FI + +  FSA    +EH  D+ ++N  FT+IP +
Sbjct: 392 RHSTGLRAFGFTLRQCYQQVGCLLLFIAMGIFTFSAAVYSVEH--DVPSTN--FTTIPHS 447

Query: 353 CWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYHELK 409
            WW  +S++TVGYGDMYP T  GR    +C+  GI+L  +PI+ +Y+ F   Y +LK
Sbjct: 448 WWWAAVSISTVGYGDMYPETHLGRFFAFLCIAFGIILNGMPISILYNKFSDYYSKLK 504


>gi|119395748 potassium voltage-gated channel subfamily A member 1
           [Homo sapiens]
          Length = 495

 Score =  219 bits (558), Expect = 4e-57
 Identities = 137/414 (33%), Positives = 220/414 (53%), Gaps = 54/414 (13%)

Query: 11  VVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRHSEAF 70
           VV+N+ G R+    + L  FP    + L G   +R        +D  RNEYFFDR+  +F
Sbjct: 39  VVINISGLRFETQLKTLAQFP----NTLLGNPKKR-----MRYFDPLRNEYFFDRNRPSF 89

Query: 71  GFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRMSDTYTFYSAD 130
             IL Y +  G+LR    +    F  E+ ++ L    +E                 +  D
Sbjct: 90  DAILYYYQSGGRLRRPVNVPLDMFSEEIKFYELGEEAMEK----------------FRED 133

Query: 131 EPGVLGRDEARPGGAEAAPSRRWLERMRRTFEEPTSSLAAQILASVSVVFVIVSMVVLCA 190
           E  +  ++E RP      P + +  ++   FE P SS  A+++A VSV+ +++S+V+ C 
Sbjct: 134 EGFI--KEEERP-----LPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILISIVIFCL 186

Query: 191 STLPDWRNAA--------ADNRSLDDRSRI-------IEAICIGWFTAECIVRFIVSKNK 235
            TLP+ ++           DN ++   S I       +E +CI WF+ E +VRF    +K
Sbjct: 187 ETLPELKDDKDFTGTVHRIDNTTVIYNSNIFTDPFFIVETLCIIWFSFELVVRFFACPSK 246

Query: 236 CEFVKRPLNIIDLLAITPYYISVLMTVFTGENSQLQRAGVTL---RVLRMMRIFWVIKLA 292
            +F K  +N ID++AI PY+I++   +   E +Q      +L   RV+R++R+F + KL+
Sbjct: 247 TDFFKNIMNFIDIVAIIPYFITLGTEIAEQEGNQKGEQATSLAILRVIRLVRVFRIFKLS 306

Query: 293 RHFIGLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKDFTSIPAA 352
           RH  GLQ LG TLK   RE+ +L+ F+ + + +FS+     E     E +   F+SIP A
Sbjct: 307 RHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE----AEEAESHFSSIPDA 362

Query: 353 CWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYH 406
            WW ++SMTTVGYGDMYP+T+ G+I+G +C ++G++ +ALP+  I  +F   YH
Sbjct: 363 FWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYH 416


>gi|25952092 potassium voltage-gated channel, shaker-related
           subfamily, member 7 [Homo sapiens]
          Length = 456

 Score =  217 bits (552), Expect = 2e-56
 Identities = 144/426 (33%), Positives = 216/426 (50%), Gaps = 68/426 (15%)

Query: 11  VVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRHSEAF 70
           +VLNV G R+      L  FP      L G  + R        YD  R EYFFDRH  +F
Sbjct: 15  LVLNVAGLRFETRARTLGRFP----DTLLGDPARRGRF-----YDDARREYFFDRHRPSF 65

Query: 71  GFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRMSDTYTFYSAD 130
             +L Y +  G+LR    +    F  E+ ++GL  A L                      
Sbjct: 66  DAVLYYYQSGGRLRRPAHVPLDVFLEEVAFYGLGAAALAR-------------------- 105

Query: 131 EPGVLGRDEARPGGAEAA-PSRRWLERMRRTFEEPTSSLAAQILASVSVVFVIVSMVVLC 189
               L  DE  P   E   P R +  ++   FE P SS AA++LA VSV+ ++VS+VV C
Sbjct: 106 ----LREDEGCPVPPERPLPRRAFARQLWLLFEFPESSQAARVLAVVSVLVILVSIVVFC 161

Query: 190 ASTLPDWRN----------AAAD-----------------NRSLDDRSRIIEAICIGWFT 222
             TLPD+R+          AAA                      +D   ++E +CI WF+
Sbjct: 162 LETLPDFRDDRDGTGLAAAAAAGPFPAPLNGSSQMPGNPPRLPFNDPFFVVETLCICWFS 221

Query: 223 AECIVRFIVSKNKCEFVKRPLNIIDLLAITPYYISVLMTVFTGENSQLQRAG--VTLRVL 280
            E +VR +V  +K  F K  +N+ID +AI PY+++ L T    +    Q+A     LRV+
Sbjct: 222 FELLVRLLVCPSKAIFFKNVMNLIDFVAILPYFVA-LGTELARQRGVGQQAMSLAILRVI 280

Query: 281 RMMRIFWVIKLARHFIGLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLE 340
           R++R+F + KL+RH  GLQ LG TL+   RE+ +L+ F+ + + +FS+     E    ++
Sbjct: 281 RLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAE----VD 336

Query: 341 TSNKDFTSIPAACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHS 400
             +  FTSIP + WW +++MTTVGYGDM P+TV G+I+G +C ++G++ ++LP+  I  +
Sbjct: 337 RVDSHFTSIPESFWWAVVTMTTVGYGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIVSN 396

Query: 401 FVQCYH 406
           F   YH
Sbjct: 397 FSYFYH 402


>gi|4826786 Shaw-related voltage-gated potassium channel protein 1
           isoform B [Homo sapiens]
          Length = 511

 Score =  214 bits (546), Expect = 9e-56
 Identities = 141/443 (31%), Positives = 220/443 (49%), Gaps = 57/443 (12%)

Query: 11  VVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRHSEAF 70
           +V+NVGG R+   R  L+  P  R++ L    +E D     D YD   +E+FFDRH   F
Sbjct: 10  IVINVGGTRHQTYRSTLRTLPGTRLAWL----AEPDAHSHFD-YDPRADEFFFDRHPGVF 64

Query: 71  GFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCC-----QRRLDDRMSDTY- 124
             IL Y R  GKL     +C   +  E+ +WG++   +E CC     Q R  +   D++ 
Sbjct: 65  AHILNYYRT-GKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFG 123

Query: 125 --------TFYSADEPGVLGRDEAR------------PGGAEAAPSRRWLERMRRTFEEP 164
                       AD PG  G  E              P G      RRW  R+   FE+P
Sbjct: 124 GAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDP 183

Query: 165 TSSLAAQILASVSVVFVIVSMVVLCAST------------LPDWRNAAADNRSLDDRSRI 212
            SS  A+ +A  S+ F++VS+   C  T            + + RN        +  +  
Sbjct: 184 YSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEA 243

Query: 213 ----IEAICIGWFTAECIVRFIVSKNKCEFVKRPLNIIDLLAITPYYISVLMTVFTGENS 268
               IE +C+ WFT E ++R I   NK EF+K  LNIID +AI P+Y+ V ++   G +S
Sbjct: 244 FLTYIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILPFYLEVGLS---GLSS 300

Query: 269 QLQRAGVT-LRVLRMMRIFWVIKLARHFIGLQTLGLTLKRCYREMVMLLVFICVAMAIFS 327
           +  +  +  LRV+R +RI  + KL RHF+GL+ LG TL+    E ++L++F+ + + IF+
Sbjct: 301 KAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFA 360

Query: 328 ALSQLLEH-----GLDLETSNKDFTSIPAACWWVIISMTTVGYGDMYPITVPGRILGGVC 382
            +    E           + +  F +IP   WW +++MTT+GYGDMYP T  G ++G +C
Sbjct: 361 TMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALC 420

Query: 383 VVSGIVLLALPITFIYHSFVQCY 405
            ++G++ +A+P+  I ++F   Y
Sbjct: 421 ALAGVLTIAMPVPVIVNNFGMYY 443


>gi|163792201 Shaw-related voltage-gated potassium channel protein 1
           isoform A [Homo sapiens]
          Length = 585

 Score =  214 bits (546), Expect = 9e-56
 Identities = 141/443 (31%), Positives = 220/443 (49%), Gaps = 57/443 (12%)

Query: 11  VVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRHSEAF 70
           +V+NVGG R+   R  L+  P  R++ L    +E D     D YD   +E+FFDRH   F
Sbjct: 10  IVINVGGTRHQTYRSTLRTLPGTRLAWL----AEPDAHSHFD-YDPRADEFFFDRHPGVF 64

Query: 71  GFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCC-----QRRLDDRMSDTY- 124
             IL Y R  GKL     +C   +  E+ +WG++   +E CC     Q R  +   D++ 
Sbjct: 65  AHILNYYRT-GKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFG 123

Query: 125 --------TFYSADEPGVLGRDEAR------------PGGAEAAPSRRWLERMRRTFEEP 164
                       AD PG  G  E              P G      RRW  R+   FE+P
Sbjct: 124 GAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDP 183

Query: 165 TSSLAAQILASVSVVFVIVSMVVLCAST------------LPDWRNAAADNRSLDDRSRI 212
            SS  A+ +A  S+ F++VS+   C  T            + + RN        +  +  
Sbjct: 184 YSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEA 243

Query: 213 ----IEAICIGWFTAECIVRFIVSKNKCEFVKRPLNIIDLLAITPYYISVLMTVFTGENS 268
               IE +C+ WFT E ++R I   NK EF+K  LNIID +AI P+Y+ V ++   G +S
Sbjct: 244 FLTYIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILPFYLEVGLS---GLSS 300

Query: 269 QLQRAGVT-LRVLRMMRIFWVIKLARHFIGLQTLGLTLKRCYREMVMLLVFICVAMAIFS 327
           +  +  +  LRV+R +RI  + KL RHF+GL+ LG TL+    E ++L++F+ + + IF+
Sbjct: 301 KAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFA 360

Query: 328 ALSQLLEH-----GLDLETSNKDFTSIPAACWWVIISMTTVGYGDMYPITVPGRILGGVC 382
            +    E           + +  F +IP   WW +++MTT+GYGDMYP T  G ++G +C
Sbjct: 361 TMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALC 420

Query: 383 VVSGIVLLALPITFIYHSFVQCY 405
            ++G++ +A+P+  I ++F   Y
Sbjct: 421 ALAGVLTIAMPVPVIVNNFGMYY 443


>gi|27436981 potassium voltage-gated channel, Shal-related
           subfamily, member 1 [Homo sapiens]
          Length = 647

 Score =  211 bits (536), Expect = 1e-54
 Identities = 137/408 (33%), Positives = 216/408 (52%), Gaps = 35/408 (8%)

Query: 7   GAASVVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRH 66
           G   +V+NV G R+   +  L  +P      L G  SE++       YD +  EYFFDR 
Sbjct: 38  GDEVLVVNVSGRRFETWKNTLDRYP----DTLLGS-SEKEFF-----YDADSGEYFFDRD 87

Query: 67  SEAFGFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRMSDTYTF 126
            + F  +L + R  G+L    + C  +F  E+ ++GL    +  CC     DR  +    
Sbjct: 88  PDMFRHVLNFYRT-GRLHCPRQECIQAFDEELAFYGLVPELVGDCCLEEYRDRKKENAER 146

Query: 127 YSADEPGVLGRDEARPGGAEAAPSRRWL-ERMRRTFEEPTSSLAAQILASVSVVFVIVSM 185
            + DE      +  + G   A P+   L +R+ R FE P +S AA +   V+  F+ VS+
Sbjct: 147 LAEDE------EAEQAGDGPALPAGSSLRQRLWRAFENPHTSTAALVFYYVTGFFIAVSV 200

Query: 186 VVLCASTLPDWRNAAADNRSLDDRSRIIEAI------CIGWFTAECIVRFIVSKNKCEFV 239
           +     T+P   +A   +R      R  +A       C+  FT E ++R   + ++C F+
Sbjct: 201 IANVVETIPCRGSARRSSREQPCGERFPQAFFCMDTACVLIFTGEYLLRLFAAPSRCRFL 260

Query: 240 KRPLNIIDLLAITPYYISVLMTVFTGENSQLQRAGVTLRVLRMMRIFWVIKLARHFIGLQ 299
           +  +++ID++AI PYYI +L+     +N  +  A VTLRV R+ RIF   K +RH  GL+
Sbjct: 261 RSVMSLIDVVAILPYYIGLLVP----KNDDVSGAFVTLRVFRVFRIF---KFSRHSQGLR 313

Query: 300 TLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKDFTSIPAACWWVIIS 359
            LG TLK C  E+  LL  + +A+ IF+ +    E G    T+  +FTSIPAA W+ I++
Sbjct: 314 ILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKG----TNKTNFTSIPAAFWYTIVT 369

Query: 360 MTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYHE 407
           MTT+GYGDM P T+ G+I G +C +SG++++ALP+  I  +F + YH+
Sbjct: 370 MTTLGYGDMVPSTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQ 417


>gi|24497460 Shaw-related voltage-gated potassium channel protein 3
           [Homo sapiens]
          Length = 757

 Score =  210 bits (535), Expect = 2e-54
 Identities = 143/475 (30%), Positives = 230/475 (48%), Gaps = 84/475 (17%)

Query: 4   GRSGAASVVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFF 63
           G   +  +V+NVGG R+   R  L+  P  R++ L    +         DYD   +E+FF
Sbjct: 83  GGGDSGKIVINVGGVRHETYRSTLRTLPGTRLAGLTEPEAAARF-----DYDPGADEFFF 137

Query: 64  DRHSEAFGFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCC---QRRLDDRM 120
           DRH   F ++L Y R  GKL     +C   F  E+ +WG++   +E CC    R+  D  
Sbjct: 138 DRHPGVFAYVLNYYRT-GKLHCPADVCGPLFEEELGFWGIDETDVEACCWMTYRQHRDAE 196

Query: 121 SDTYTFYSADEPGVLGR------------DEAR--------------------------- 141
               +F + D  G                DEA                            
Sbjct: 197 EALDSFEAPDPAGAANAANAAGAHDGGLDDEAGAGGGGLDGAGGELKRLCFQDAGGGAGG 256

Query: 142 -PGGAEAAPS---RRWLERMRRTFEEPTSSLAAQILASVSVVFVIVSMVVLCASTLPDWR 197
            PGGA  A     RRW  R+   FE+P SS AA+ +A  S+ F+++S+   C  T   + 
Sbjct: 257 PPGGAGGAGGTWWRRWQPRVWALFEDPYSSRAARYVAFASLFFILISITTFCLETHEGFI 316

Query: 198 NAAADNRSLDDRSRI---------------------IEAICIGWFTAECIVRFIVSKNKC 236
           + +  N+++   S I                     +E +C+ WFT E ++R     +K 
Sbjct: 317 HIS--NKTVTQASPIPGAPPENITNVEVETEPFLTYVEGVCVVWFTFEFLMRITFCPDKV 374

Query: 237 EFVKRPLNIIDLLAITPYYISVLMTVFTGENSQLQRAGVT-LRVLRMMRIFWVIKLARHF 295
           EF+K  LNIID +AI P+Y+ V ++   G +S+  +  +  LRV+R +RI  + KL RHF
Sbjct: 375 EFLKSSLNIIDCVAILPFYLEVGLS---GLSSKAAKDVLGFLRVVRFVRILRIFKLTRHF 431

Query: 296 IGLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEH-GLD----LETSNKDFTSIP 350
           +GL+ LG TL+    E ++L++F+ + + IF+ +    E  G D    L +++  F +IP
Sbjct: 432 VGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPDDILGSNHTYFKNIP 491

Query: 351 AACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCY 405
              WW +++MTT+GYGDMYP T  G ++G +C ++G++ +A+P+  I ++F   Y
Sbjct: 492 IGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 546


>gi|88758576 Shaw-related voltage-gated potassium channel protein 4
           isoform c [Homo sapiens]
          Length = 626

 Score =  210 bits (535), Expect = 2e-54
 Identities = 145/446 (32%), Positives = 221/446 (49%), Gaps = 55/446 (12%)

Query: 11  VVLNVGGARYSLSRELLKDFPLRRVSRLH----GCRSERDVLEVCDDYDRERN--EYFFD 64
           +++NVGG R+   R  L+  P  R++ L     G R E D   V           E+FFD
Sbjct: 38  IIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPETDGGGVGSSGSSGGGGCEFFFD 97

Query: 65  RHSEAFGFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCC---QRRLDDRMS 121
           RH   F ++L Y R  GKL     +C   F  E+ +WG++   +E CC    R+  D   
Sbjct: 98  RHPGVFAYVLNYYRT-GKLHCPADVCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDAEE 156

Query: 122 DTYTFYSADEPGV-------------------LGRDEARPG-GAEAAPSRRWLERMRRTF 161
               F S D  G                    LG  E   G GA +   R W  RM   F
Sbjct: 157 ALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGGCRGWQPRMWALF 216

Query: 162 EEPTSSLAAQILASVSVVFVIVSMVVLCASTLPDW---RNAAADNR-----SLDDRSRI- 212
           E+P SS AA+++A  S+ F++VS+   C  T   +   RN     R     S+  R  + 
Sbjct: 217 EDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEILRVGNITSVHFRREVE 276

Query: 213 -------IEAICIGWFTAECIVRFIVSKNKCEFVKRPLNIIDLLAITPYYISVLMTVFTG 265
                  IE +C+ WFT E +VR +   +  +FVK  LNIID +AI P+Y+ V ++   G
Sbjct: 277 TEPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVAILPFYLEVGLS---G 333

Query: 266 ENSQLQRAGVT-LRVLRMMRIFWVIKLARHFIGLQTLGLTLKRCYREMVMLLVFICVAMA 324
            +S+  R  +  LRV+R +RI  + KL RHF+GL+ LG TL+    E ++L++F+ + + 
Sbjct: 334 LSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVL 393

Query: 325 IFSALSQLLEH-----GLDLETSNKDFTSIPAACWWVIISMTTVGYGDMYPITVPGRILG 379
           IF+ +    E             + DF +IP   WW +++MTT+GYGDMYP T  G ++G
Sbjct: 394 IFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVG 453

Query: 380 GVCVVSGIVLLALPITFIYHSFVQCY 405
            +C ++G++ +A+P+  I ++F   Y
Sbjct: 454 ALCALAGVLTIAMPVPVIVNNFGMYY 479


>gi|24497462 Shaw-related voltage-gated potassium channel protein 4
           isoform a [Homo sapiens]
          Length = 635

 Score =  210 bits (535), Expect = 2e-54
 Identities = 145/446 (32%), Positives = 221/446 (49%), Gaps = 55/446 (12%)

Query: 11  VVLNVGGARYSLSRELLKDFPLRRVSRLH----GCRSERDVLEVCDDYDRERN--EYFFD 64
           +++NVGG R+   R  L+  P  R++ L     G R E D   V           E+FFD
Sbjct: 38  IIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPETDGGGVGSSGSSGGGGCEFFFD 97

Query: 65  RHSEAFGFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCC---QRRLDDRMS 121
           RH   F ++L Y R  GKL     +C   F  E+ +WG++   +E CC    R+  D   
Sbjct: 98  RHPGVFAYVLNYYRT-GKLHCPADVCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDAEE 156

Query: 122 DTYTFYSADEPGV-------------------LGRDEARPG-GAEAAPSRRWLERMRRTF 161
               F S D  G                    LG  E   G GA +   R W  RM   F
Sbjct: 157 ALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGGCRGWQPRMWALF 216

Query: 162 EEPTSSLAAQILASVSVVFVIVSMVVLCASTLPDW---RNAAADNR-----SLDDRSRI- 212
           E+P SS AA+++A  S+ F++VS+   C  T   +   RN     R     S+  R  + 
Sbjct: 217 EDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEILRVGNITSVHFRREVE 276

Query: 213 -------IEAICIGWFTAECIVRFIVSKNKCEFVKRPLNIIDLLAITPYYISVLMTVFTG 265
                  IE +C+ WFT E +VR +   +  +FVK  LNIID +AI P+Y+ V ++   G
Sbjct: 277 TEPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVAILPFYLEVGLS---G 333

Query: 266 ENSQLQRAGVT-LRVLRMMRIFWVIKLARHFIGLQTLGLTLKRCYREMVMLLVFICVAMA 324
            +S+  R  +  LRV+R +RI  + KL RHF+GL+ LG TL+    E ++L++F+ + + 
Sbjct: 334 LSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVL 393

Query: 325 IFSALSQLLEH-----GLDLETSNKDFTSIPAACWWVIISMTTVGYGDMYPITVPGRILG 379
           IF+ +    E             + DF +IP   WW +++MTT+GYGDMYP T  G ++G
Sbjct: 394 IFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVG 453

Query: 380 GVCVVSGIVLLALPITFIYHSFVQCY 405
            +C ++G++ +A+P+  I ++F   Y
Sbjct: 454 ALCALAGVLTIAMPVPVIVNNFGMYY 479


>gi|24497464 Shaw-related voltage-gated potassium channel protein 4
           isoform b [Homo sapiens]
          Length = 582

 Score =  210 bits (535), Expect = 2e-54
 Identities = 145/446 (32%), Positives = 221/446 (49%), Gaps = 55/446 (12%)

Query: 11  VVLNVGGARYSLSRELLKDFPLRRVSRLH----GCRSERDVLEVCDDYDRERN--EYFFD 64
           +++NVGG R+   R  L+  P  R++ L     G R E D   V           E+FFD
Sbjct: 38  IIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPETDGGGVGSSGSSGGGGCEFFFD 97

Query: 65  RHSEAFGFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCC---QRRLDDRMS 121
           RH   F ++L Y R  GKL     +C   F  E+ +WG++   +E CC    R+  D   
Sbjct: 98  RHPGVFAYVLNYYRT-GKLHCPADVCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDAEE 156

Query: 122 DTYTFYSADEPGV-------------------LGRDEARPG-GAEAAPSRRWLERMRRTF 161
               F S D  G                    LG  E   G GA +   R W  RM   F
Sbjct: 157 ALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGGCRGWQPRMWALF 216

Query: 162 EEPTSSLAAQILASVSVVFVIVSMVVLCASTLPDW---RNAAADNR-----SLDDRSRI- 212
           E+P SS AA+++A  S+ F++VS+   C  T   +   RN     R     S+  R  + 
Sbjct: 217 EDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEILRVGNITSVHFRREVE 276

Query: 213 -------IEAICIGWFTAECIVRFIVSKNKCEFVKRPLNIIDLLAITPYYISVLMTVFTG 265
                  IE +C+ WFT E +VR +   +  +FVK  LNIID +AI P+Y+ V ++   G
Sbjct: 277 TEPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVAILPFYLEVGLS---G 333

Query: 266 ENSQLQRAGVT-LRVLRMMRIFWVIKLARHFIGLQTLGLTLKRCYREMVMLLVFICVAMA 324
            +S+  R  +  LRV+R +RI  + KL RHF+GL+ LG TL+    E ++L++F+ + + 
Sbjct: 334 LSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVL 393

Query: 325 IFSALSQLLEH-----GLDLETSNKDFTSIPAACWWVIISMTTVGYGDMYPITVPGRILG 379
           IF+ +    E             + DF +IP   WW +++MTT+GYGDMYP T  G ++G
Sbjct: 394 IFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVG 453

Query: 380 GVCVVSGIVLLALPITFIYHSFVQCY 405
            +C ++G++ +A+P+  I ++F   Y
Sbjct: 454 ALCALAGVLTIAMPVPVIVNNFGMYY 479


>gi|88758565 potassium voltage-gated channel, shaker-related
           subfamily, member 3 [Homo sapiens]
          Length = 575

 Score =  209 bits (533), Expect = 3e-54
 Identities = 135/419 (32%), Positives = 221/419 (52%), Gaps = 59/419 (14%)

Query: 11  VVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRHSEAF 70
           VV+N+ G R+    + L  FP      L G    R        +D  RNEYFFDR+  +F
Sbjct: 106 VVINISGLRFETQLKTLCQFP----ETLLGDPKRR-----MRYFDPLRNEYFFDRNRPSF 156

Query: 71  GFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRMSDTYTFYSAD 130
             IL Y +  G++R  P    +  ++E I +             +L +   + +     +
Sbjct: 157 DAILYYYQSGGRIR-RPVNVPIDIFSEEIRF------------YQLGEEAMEKFR----E 199

Query: 131 EPGVLGRDEARPGGAEAAPSRRWLERMRRTFEEPTSSLAAQILASVSVVFVIVSMVVLCA 190
           + G L R+E RP      P R +  ++   FE P SS  A+ +A VSV+ +++S+V+ C 
Sbjct: 200 DEGFL-REEERP-----LPRRDFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCL 253

Query: 191 STLPDWR------------------NAAADNR----SLDDRSRIIEAICIGWFTAECIVR 228
            TLP++R                  N+ + +R    S  D   ++E +CI WF+ E +VR
Sbjct: 254 ETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFVVETLCIIWFSFELLVR 313

Query: 229 FIVSKNKCEFVKRPLNIIDLLAITPYYISVLMTVFTGE-NSQLQRAGVTLRVLRMMRIFW 287
           F    +K  F +  +N+ID++AI PY+I++   +   + N Q   +   LRV+R++R+F 
Sbjct: 314 FFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMSLAILRVIRLVRVFR 373

Query: 288 VIKLARHFIGLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKDFT 347
           + KL+RH  GLQ LG TLK   RE+ +L+ F+ + + +FS+     E     +     F+
Sbjct: 374 IFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE----ADDPTSGFS 429

Query: 348 SIPAACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYH 406
           SIP A WW +++MTTVGYGDM+P+T+ G+I+G +C ++G++ +ALP+  I  +F   YH
Sbjct: 430 SIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYH 488


>gi|5031819 potassium voltage-gated channel, shaker-related
           subfamily, member 10 [Homo sapiens]
          Length = 511

 Score =  208 bits (529), Expect = 9e-54
 Identities = 131/418 (31%), Positives = 212/418 (50%), Gaps = 54/418 (12%)

Query: 7   GAASVVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRH 66
           G   V++N+ G R+      L  FP      L G R +R        +D  RNEYFFDR+
Sbjct: 84  GNQRVIINIAGLRFETQLRTLSQFP----ETLLGDREKR-----MQFFDSMRNEYFFDRN 134

Query: 67  SEAFGFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRMSDTYTF 126
             +F  IL Y +  GK+R    +    F +E+ ++ L    +         D+  +   F
Sbjct: 135 RPSFDGILYYYQSGGKIRRPANVPIDIFADEISFYELGSEAM---------DQFREDEGF 185

Query: 127 YSADEPGVLGRDEARPGGAEAAPSRRWLERMRRTFEEPTSSLAAQILASVSVVFVIVSMV 186
               E  +   D  R         + WL      FE P SS AA+ +A VSV+ V++S+ 
Sbjct: 186 IKDPETLLPTNDIHR---------QFWL-----LFEYPESSSAARAVAVVSVLVVVISIT 231

Query: 187 VLCASTLPDWRN----------------AAADNRSLDDRSRIIEAICIGWFTAECIVRFI 230
           + C  TLP++R                          D   ++E+ CI WFT E ++RF+
Sbjct: 232 IFCLETLPEFREDRELKVVRDPNLNMSKTVLSQTMFTDPFFMVESTCIVWFTFELVLRFV 291

Query: 231 VSKNKCEFVKRPLNIIDLLAITPYYISVLMTVF--TGENSQLQRAGVTLRVLRMMRIFWV 288
           V  +K +F +  +NIID+++I PY+ +++  +   T  ++Q   +   LR++R++R+F +
Sbjct: 292 VCPSKTDFFRNIMNIIDIISIIPYFATLITELVQETEPSAQQNMSLAILRIIRLVRVFRI 351

Query: 289 IKLARHFIGLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKDFTS 348
            KL+RH  GLQ LG TLK   RE+ +L+ F+ + + +FS+     E    ++     F+S
Sbjct: 352 FKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE----VDEPESHFSS 407

Query: 349 IPAACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYH 406
           IP   WW +++MTTVGYGDM P T  G+I+G +C ++G++ +ALP+  I  +F   YH
Sbjct: 408 IPDGFWWAVVTMTTVGYGDMCPTTPGGKIVGTLCAIAGVLTIALPVPVIVSNFNYFYH 465


>gi|9789987 potassium voltage-gated channel, Shal-related subfamily,
           member 2 [Homo sapiens]
          Length = 630

 Score =  207 bits (527), Expect = 1e-53
 Identities = 138/409 (33%), Positives = 213/409 (52%), Gaps = 36/409 (8%)

Query: 5   RSGAASVVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFD 64
           R+  A +VLNV G R+   ++ L+ +P      L G  SERD       Y  E  +YFFD
Sbjct: 37  RTQDALIVLNVSGTRFQTWQDTLERYP----DTLLGS-SERDFF-----YHPETQQYFFD 86

Query: 65  RHSEAFGFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRMSDTY 124
           R  + F  IL + R  GKL +    C  ++  E+ ++GL    +  CC     DR  +  
Sbjct: 87  RDPDIFRHILNFYRT-GKLHYPRHECISAYDEELAFFGLIPEIIGDCCYEEYKDRRRENA 145

Query: 125 TFYSADEPGVLGRDEARPGGAEAAPSRRWLERMRRTFEEPTSSLAAQILASVSVVFVIVS 184
                D        +    G  A P+    +R+ R FE P +S  A +   V+  F+ VS
Sbjct: 146 ERLQDDA-------DTDTAGESALPTMTARQRVWRAFENPHTSTMALVFYYVTGFFIAVS 198

Query: 185 MVVLCASTLPDWRNAAADNRSLDDRSRI------IEAICIGWFTAECIVRFIVSKNKCEF 238
           ++     T+P   ++    + L    R       ++  C+  FT E ++R   + ++  F
Sbjct: 199 VIANVVETVP-CGSSPGHIKELPCGERYAVAFFCLDTACVMIFTVEYLLRLAAAPSRYRF 257

Query: 239 VKRPLNIIDLLAITPYYISVLMTVFTGENSQLQRAGVTLRVLRMMRIFWVIKLARHFIGL 298
           V+  ++IID++AI PYYI ++MT    +N  +  A VTLRV R+ RIF   K +RH  GL
Sbjct: 258 VRSVMSIIDVVAILPYYIGLVMT----DNEDVSGAFVTLRVFRVFRIF---KFSRHSQGL 310

Query: 299 QTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKDFTSIPAACWWVII 358
           + LG TLK C  E+  LL  + +A+ IF+ +    E G    +S   FTSIPAA W+ I+
Sbjct: 311 RILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKG----SSASKFTSIPAAFWYTIV 366

Query: 359 SMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYHE 407
           +MTT+GYGDM P T+ G+I G +C +SG++++ALP+  I  +F + YH+
Sbjct: 367 TMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQ 415


>gi|4826782 potassium voltage-gated channel, shaker-related
           subfamily, member 2 [Homo sapiens]
          Length = 499

 Score =  207 bits (526), Expect = 2e-53
 Identities = 137/420 (32%), Positives = 210/420 (50%), Gaps = 60/420 (14%)

Query: 11  VVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRHSEAF 70
           VV+N+ G R+    + L  FP      L G   +R        +D  RNEYFFDR+  +F
Sbjct: 35  VVINISGLRFETQLKTLAQFP----ETLLGDPKKR-----MRYFDPLRNEYFFDRNRPSF 85

Query: 71  GFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRMSDTYTFYSAD 130
             IL Y +  G+LR  P    L  ++E I               R  +   +    +  D
Sbjct: 86  DAILYYYQSGGRLR-RPVNVPLDIFSEEI---------------RFYELGEEAMEMFRED 129

Query: 131 EPGVLGRDEARPGGAEAAPSRRWLERMRRTFEEPTSSLAAQILASVSVVFVIVSMVVLCA 190
           E  +  ++E RP      P   +  ++   FE P SS  A+I+A VSV+ +++S+V  C 
Sbjct: 130 EGYI--KEEERP-----LPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCL 182

Query: 191 STLPDWRNAAAD--------------------NRSLDDRSRIIEAICIGWFTAECIVRFI 230
            TLP +R+   D                    + S  D   I+E +CI WF+ E +VRF 
Sbjct: 183 ETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFF 242

Query: 231 VSKNKCEFVKRPLNIIDLLAITPYYISVLMTVFT----GENSQLQRAGVTLRVLRMMRIF 286
              +K  F    +NIID++AI PY+I++   +       +  Q   +   LRV+R++R+F
Sbjct: 243 ACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVIRLVRVF 302

Query: 287 WVIKLARHFIGLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKDF 346
            + KL+RH  GLQ LG TLK   RE+ +L+ F+ + + +FS+     E     +     F
Sbjct: 303 RIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE----ADERESQF 358

Query: 347 TSIPAACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYH 406
            SIP A WW ++SMTTVGYGDM P T+ G+I+G +C ++G++ +ALP+  I  +F   YH
Sbjct: 359 PSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYH 418


>gi|21217561 Shaw-related voltage-gated potassium channel protein 2
           isoform KV3.2a [Homo sapiens]
          Length = 613

 Score =  207 bits (526), Expect = 2e-53
 Identities = 142/475 (29%), Positives = 221/475 (46%), Gaps = 84/475 (17%)

Query: 11  VVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVC------------------- 51
           V+LNVGG R+   R  LK  P  R++ L       D L                      
Sbjct: 10  VILNVGGTRHETYRSTLKTLPGTRLALLASSEPPGDCLTTAGDKLQPSPPPLSPPPRAPP 69

Query: 52  -----------------------DDYDRERNEYFFDRHSEAFGFILLYVRGHGKLRFAPR 88
                                   D+     E+FFDRH   F ++L Y R  GKL     
Sbjct: 70  LSPGPGGCFEGGAGNCSSRGGRASDHPGGGREFFFDRHPGVFAYVLNYYRT-GKLHCPAD 128

Query: 89  MCELSFYNEMIYWGLEGAHLEYCC---QRRLDDRMSDTYTFYSAD----EPGV------- 134
           +C   F  E+ +WG++   +E CC    R+  D       F + D    +PG        
Sbjct: 129 VCGPLFEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDIFETPDLIGGDPGDDEDLAAK 188

Query: 135 -LGRDEARPGGAEAAPSRRWLE---RMRRTFEEPTSSLAAQILASVSVVFVIVSMVVLCA 190
            LG ++A   G     S RW     RM   FE+P SS AA+ +A  S+ F++VS+   C 
Sbjct: 189 RLGIEDAAGLGGPDGKSGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCL 248

Query: 191 ST------LPDWRNAAADNRSL--------DDRSRIIEAICIGWFTAECIVRFIVSKNKC 236
            T      + +      +  S+        D     +E +C+ WFT E +VR + S NK 
Sbjct: 249 ETHEAFNIVKNKTEPVINGTSVVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVFSPNKL 308

Query: 237 EFVKRPLNIIDLLAITPYYISVLMTVFTGENSQLQRAGVT-LRVLRMMRIFWVIKLARHF 295
           EF+K  LNIID +AI P+Y+ V ++   G +S+  +  +  LRV+R +RI  + KL RHF
Sbjct: 309 EFIKNLLNIIDFVAILPFYLEVGLS---GLSSKAAKDVLGFLRVVRFVRILRIFKLTRHF 365

Query: 296 IGLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEH-----GLDLETSNKDFTSIP 350
           +GL+ LG TL+    E ++L++F+ + + IF+ +    E           + +  F +IP
Sbjct: 366 VGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIP 425

Query: 351 AACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCY 405
              WW +++MTT+GYGDMYP T  G ++G +C ++G++ +A+P+  I ++F   Y
Sbjct: 426 IGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 480


>gi|21217563 Shaw-related voltage-gated potassium channel protein 2
           isoform KV3.2b [Homo sapiens]
          Length = 638

 Score =  207 bits (526), Expect = 2e-53
 Identities = 142/475 (29%), Positives = 221/475 (46%), Gaps = 84/475 (17%)

Query: 11  VVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVC------------------- 51
           V+LNVGG R+   R  LK  P  R++ L       D L                      
Sbjct: 10  VILNVGGTRHETYRSTLKTLPGTRLALLASSEPPGDCLTTAGDKLQPSPPPLSPPPRAPP 69

Query: 52  -----------------------DDYDRERNEYFFDRHSEAFGFILLYVRGHGKLRFAPR 88
                                   D+     E+FFDRH   F ++L Y R  GKL     
Sbjct: 70  LSPGPGGCFEGGAGNCSSRGGRASDHPGGGREFFFDRHPGVFAYVLNYYRT-GKLHCPAD 128

Query: 89  MCELSFYNEMIYWGLEGAHLEYCC---QRRLDDRMSDTYTFYSAD----EPGV------- 134
           +C   F  E+ +WG++   +E CC    R+  D       F + D    +PG        
Sbjct: 129 VCGPLFEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDIFETPDLIGGDPGDDEDLAAK 188

Query: 135 -LGRDEARPGGAEAAPSRRWLE---RMRRTFEEPTSSLAAQILASVSVVFVIVSMVVLCA 190
            LG ++A   G     S RW     RM   FE+P SS AA+ +A  S+ F++VS+   C 
Sbjct: 189 RLGIEDAAGLGGPDGKSGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCL 248

Query: 191 ST------LPDWRNAAADNRSL--------DDRSRIIEAICIGWFTAECIVRFIVSKNKC 236
            T      + +      +  S+        D     +E +C+ WFT E +VR + S NK 
Sbjct: 249 ETHEAFNIVKNKTEPVINGTSVVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVFSPNKL 308

Query: 237 EFVKRPLNIIDLLAITPYYISVLMTVFTGENSQLQRAGVT-LRVLRMMRIFWVIKLARHF 295
           EF+K  LNIID +AI P+Y+ V ++   G +S+  +  +  LRV+R +RI  + KL RHF
Sbjct: 309 EFIKNLLNIIDFVAILPFYLEVGLS---GLSSKAAKDVLGFLRVVRFVRILRIFKLTRHF 365

Query: 296 IGLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEH-----GLDLETSNKDFTSIP 350
           +GL+ LG TL+    E ++L++F+ + + IF+ +    E           + +  F +IP
Sbjct: 366 VGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIP 425

Query: 351 AACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCY 405
              WW +++MTT+GYGDMYP T  G ++G +C ++G++ +A+P+  I ++F   Y
Sbjct: 426 IGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 480


>gi|24497458 Shaw-related voltage-gated potassium channel protein 2
           isoform KV3.2c [Homo sapiens]
          Length = 558

 Score =  207 bits (526), Expect = 2e-53
 Identities = 142/475 (29%), Positives = 221/475 (46%), Gaps = 84/475 (17%)

Query: 11  VVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVC------------------- 51
           V+LNVGG R+   R  LK  P  R++ L       D L                      
Sbjct: 10  VILNVGGTRHETYRSTLKTLPGTRLALLASSEPPGDCLTTAGDKLQPSPPPLSPPPRAPP 69

Query: 52  -----------------------DDYDRERNEYFFDRHSEAFGFILLYVRGHGKLRFAPR 88
                                   D+     E+FFDRH   F ++L Y R  GKL     
Sbjct: 70  LSPGPGGCFEGGAGNCSSRGGRASDHPGGGREFFFDRHPGVFAYVLNYYRT-GKLHCPAD 128

Query: 89  MCELSFYNEMIYWGLEGAHLEYCC---QRRLDDRMSDTYTFYSAD----EPGV------- 134
           +C   F  E+ +WG++   +E CC    R+  D       F + D    +PG        
Sbjct: 129 VCGPLFEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDIFETPDLIGGDPGDDEDLAAK 188

Query: 135 -LGRDEARPGGAEAAPSRRWLE---RMRRTFEEPTSSLAAQILASVSVVFVIVSMVVLCA 190
            LG ++A   G     S RW     RM   FE+P SS AA+ +A  S+ F++VS+   C 
Sbjct: 189 RLGIEDAAGLGGPDGKSGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCL 248

Query: 191 ST------LPDWRNAAADNRSL--------DDRSRIIEAICIGWFTAECIVRFIVSKNKC 236
            T      + +      +  S+        D     +E +C+ WFT E +VR + S NK 
Sbjct: 249 ETHEAFNIVKNKTEPVINGTSVVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVFSPNKL 308

Query: 237 EFVKRPLNIIDLLAITPYYISVLMTVFTGENSQLQRAGVT-LRVLRMMRIFWVIKLARHF 295
           EF+K  LNIID +AI P+Y+ V ++   G +S+  +  +  LRV+R +RI  + KL RHF
Sbjct: 309 EFIKNLLNIIDFVAILPFYLEVGLS---GLSSKAAKDVLGFLRVVRFVRILRIFKLTRHF 365

Query: 296 IGLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEH-----GLDLETSNKDFTSIP 350
           +GL+ LG TL+    E ++L++F+ + + IF+ +    E           + +  F +IP
Sbjct: 366 VGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIP 425

Query: 351 AACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCY 405
              WW +++MTT+GYGDMYP T  G ++G +C ++G++ +A+P+  I ++F   Y
Sbjct: 426 IGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 480


>gi|4504817 potassium voltage-gated channel, shaker-related
           subfamily, member 4 [Homo sapiens]
          Length = 653

 Score =  204 bits (519), Expect = 1e-52
 Identities = 139/427 (32%), Positives = 219/427 (51%), Gaps = 67/427 (15%)

Query: 11  VVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRHSEAF 70
           VV+NV G R+    + L  FP      L G   +R        +D  RNEYFFDR+  +F
Sbjct: 178 VVINVSGLRFETQMKTLAQFP----ETLLGDPEKRTQY-----FDPLRNEYFFDRNRPSF 228

Query: 71  GFILLYVRGHGKLRFAPRMCELSFYNEMIYWGL-EGAHLEYCCQRRLDDRMSDTYTFYSA 129
             IL Y +  G+L+    +    F  E+ ++ L E A L++                   
Sbjct: 229 DAILYYYQSGGRLKRPVNVPFDIFTEEVKFYQLGEEALLKF------------------R 270

Query: 130 DEPGVLGRDEARPGGAEAAPSRRWLERMRRTFEEPTSSLAAQILASVSVVFVIVSMVVLC 189
           ++ G +  +E R     A P   + +++   FE P SS  A+ +A VSV+ +++S+V+ C
Sbjct: 271 EDEGFVREEEDR-----ALPENEFKKQIWLLFEYPESSSPARGIAIVSVLVILISIVIFC 325

Query: 190 ASTLPDWRN---------AAADNRSLDDRSR----------------IIEAICIGWFTAE 224
             TLP++R+         A      L+D S                 I+E +CI WF+ E
Sbjct: 326 LETLPEFRDDRDLVMALSAGGHGGLLNDTSAPHLENSGHTIFNDPFFIVETVCIVWFSFE 385

Query: 225 CIVRFIVSKNKCEFVKRPLNIIDLLAITPYYISV---LMTVFTGENSQLQRAG--VTLRV 279
            +VR     ++  F K  +NIID+++I PY+I++   L     G N Q Q+A     LR+
Sbjct: 386 FVVRCFACPSQALFFKNIMNIIDIVSILPYFITLGTDLAQQQGGGNGQQQQAMSFAILRI 445

Query: 280 LRMMRIFWVIKLARHFIGLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDL 339
           +R++R+F + KL+RH  GLQ LG TL+   RE+ +L+ F+ + + +FS+     E     
Sbjct: 446 IRLVRVFRIFKLSRHSKGLQILGHTLRASMRELGLLIFFLFIGVILFSSAVYFAE----A 501

Query: 340 ETSNKDFTSIPAACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYH 399
           +     F SIP A WW +++MTTVGYGDM PITV G+I+G +C ++G++ +ALP+  I  
Sbjct: 502 DEPTTHFQSIPDAFWWAVVTMTTVGYGDMKPITVGGKIVGSLCAIAGVLTIALPVPVIVS 561

Query: 400 SFVQCYH 406
           +F   YH
Sbjct: 562 NFNYFYH 568


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.141    0.437 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,678,196
Number of Sequences: 37866
Number of extensions: 604235
Number of successful extensions: 2140
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 80
Number of HSP's successfully gapped in prelim test: 47
Number of HSP's that attempted gapping in prelim test: 1785
Number of HSP's gapped (non-prelim): 209
length of query: 425
length of database: 18,247,518
effective HSP length: 105
effective length of query: 320
effective length of database: 14,271,588
effective search space: 4566908160
effective search space used: 4566908160
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.