Guide to the Human Genome
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Search of human proteins with 27436887

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|27436887 pre-B-cell leukemia homeobox 2 [Homo sapiens]
         (430 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|27436887 pre-B-cell leukemia homeobox 2 [Homo sapiens]             869   0.0  
gi|4505623 pre-B-cell leukemia homeobox 1 [Homo sapiens]              634   0.0  
gi|5453852 pre-B-cell leukemia homeobox 3 isoform 1 [Homo sapiens]    631   0.0  
gi|198041755 pre-B-cell leukemia homeobox 3 isoform 2 [Homo sapi...   560   e-160
gi|15149472 pre-B-cell leukemia homeobox 4 [Homo sapiens]             472   e-133
gi|57863279 Meis1, myeloid ecotropic viral integration site 1 ho...    68   2e-11
gi|24762241 Meis homeobox 2 isoform c [Homo sapiens]                   66   5e-11
gi|27502381 Meis homeobox 2 isoform g [Homo sapiens]                   64   2e-10
gi|24762244 Meis homeobox 2 isoform a [Homo sapiens]                   64   2e-10
gi|4505151 Meis homeobox 1 [Homo sapiens]                              63   5e-10
gi|27502383 Meis homeobox 2 isoform h [Homo sapiens]                   63   5e-10
gi|24762250 Meis homeobox 2 isoform d [Homo sapiens]                   63   5e-10
gi|24762246 Meis homeobox 2 isoform b [Homo sapiens]                   63   5e-10
gi|24762225 Meis homeobox 2 isoform f [Homo sapiens]                   63   5e-10
gi|4885597 sine oculis homeobox homolog 3 [Homo sapiens]               61   2e-09
gi|116812644 PBX/knotted 1 homeobox 2 [Homo sapiens]                   61   2e-09
gi|28866955 PBX/knotted 1 homeobox 1 [Homo sapiens]                    59   8e-09
gi|34328941 TGFB-induced factor homeobox 2-like, X-linked [Homo ...    57   4e-08
gi|219275578 SIX homeobox 2 [Homo sapiens]                             55   2e-07
gi|5174681 SIX homeobox 1 [Homo sapiens]                               53   5e-07
gi|28178843 TG-interacting factor isoform a [Homo sapiens]             53   5e-07
gi|4507473 TG-interacting factor isoform c [Homo sapiens]              53   5e-07
gi|28178855 TG-interacting factor isoform d [Homo sapiens]             53   5e-07
gi|28178853 TG-interacting factor isoform d [Homo sapiens]             53   5e-07
gi|28178851 TG-interacting factor isoform d [Homo sapiens]             53   5e-07
gi|28178857 TG-interacting factor isoform d [Homo sapiens]             53   5e-07
gi|28178849 TG-interacting factor isoform c [Homo sapiens]             53   5e-07
gi|28178845 TG-interacting factor isoform b [Homo sapiens]             53   5e-07
gi|21245108 TGFB-induced factor homeobox 2-like, Y-linked [Homo ...    52   1e-06
gi|7705555 iroquois homeobox 4 [Homo sapiens]                          52   1e-06

>gi|27436887 pre-B-cell leukemia homeobox 2 [Homo sapiens]
          Length = 430

 Score =  869 bits (2245), Expect = 0.0
 Identities = 430/430 (100%), Positives = 430/430 (100%)

Query: 1   MDERLLGPPPPGGGRGGLGLVSGEPGGPGEPPGGGDPGGGSGGVPGGRGKQDIGDILQQI 60
           MDERLLGPPPPGGGRGGLGLVSGEPGGPGEPPGGGDPGGGSGGVPGGRGKQDIGDILQQI
Sbjct: 1   MDERLLGPPPPGGGRGGLGLVSGEPGGPGEPPGGGDPGGGSGGVPGGRGKQDIGDILQQI 60

Query: 61  MTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRSSQEEEPVDPQLMRLDN 120
           MTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRSSQEEEPVDPQLMRLDN
Sbjct: 61  MTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRSSQEEEPVDPQLMRLDN 120

Query: 121 MLLAEGVAGPEKGGGSAAAAAAAAASGGGVSPDNSIEHSDYRSKLAQIRHIYHSELEKYE 180
           MLLAEGVAGPEKGGGSAAAAAAAAASGGGVSPDNSIEHSDYRSKLAQIRHIYHSELEKYE
Sbjct: 121 MLLAEGVAGPEKGGGSAAAAAAAAASGGGVSPDNSIEHSDYRSKLAQIRHIYHSELEKYE 180

Query: 181 QACNEFTTHVMNLLREQSRTRPVAPKEMERMVSIIHRKFSAIQMQLKQSTCEAVMILRSR 240
           QACNEFTTHVMNLLREQSRTRPVAPKEMERMVSIIHRKFSAIQMQLKQSTCEAVMILRSR
Sbjct: 181 QACNEFTTHVMNLLREQSRTRPVAPKEMERMVSIIHRKFSAIQMQLKQSTCEAVMILRSR 240

Query: 241 FLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRI 300
           FLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRI
Sbjct: 241 FLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRI 300

Query: 301 RYKKNIGKFQEEANIYAVKTAVSVTQGGHSRTSSPTPPSSAGSGGSFNLSGSGDMFLGMP 360
           RYKKNIGKFQEEANIYAVKTAVSVTQGGHSRTSSPTPPSSAGSGGSFNLSGSGDMFLGMP
Sbjct: 301 RYKKNIGKFQEEANIYAVKTAVSVTQGGHSRTSSPTPPSSAGSGGSFNLSGSGDMFLGMP 360

Query: 361 GLNGDSYSASQVESLRHSMGPGGYGDNLGGGQMYSPREMRANGSWQEAVTPSSVTSPTEG 420
           GLNGDSYSASQVESLRHSMGPGGYGDNLGGGQMYSPREMRANGSWQEAVTPSSVTSPTEG
Sbjct: 361 GLNGDSYSASQVESLRHSMGPGGYGDNLGGGQMYSPREMRANGSWQEAVTPSSVTSPTEG 420

Query: 421 PGSVHSDTSN 430
           PGSVHSDTSN
Sbjct: 421 PGSVHSDTSN 430


>gi|4505623 pre-B-cell leukemia homeobox 1 [Homo sapiens]
          Length = 430

 Score =  634 bits (1634), Expect = 0.0
 Identities = 330/419 (78%), Positives = 359/419 (85%), Gaps = 14/419 (3%)

Query: 23  GEPGGPGEPPGGGDPGGGSGGVPGGRGKQDIGDILQQIMTITDQSLDEAQAKKHALNCHR 82
           G  G PG      D  GG+ G  GGR KQDIGDILQQIMTITDQSLDEAQA+KHALNCHR
Sbjct: 15  GMAGHPGLSQHLQDGAGGTEG-EGGR-KQDIGDILQQIMTITDQSLDEAQARKHALNCHR 72

Query: 83  MKPALFSVLCEIKEKTGLSIRSSQEEEPVDPQLMRLDNMLLAEGVAGPEKGGGSAAAAAA 142
           MKPALF+VLCEIKEKT LSIR +QEEEP DPQLMRLDNMLLAEGVAGPEKGGGSAAAAAA
Sbjct: 73  MKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDNMLLAEGVAGPEKGGGSAAAAAA 132

Query: 143 AAASGGGVSPDNSIEHSDYRSKLAQIRHIYHSELEKYEQACNEFTTHVMNLLREQSRTRP 202
           AAASGG  S DNS+EHSDYR+KL+QIR IYH+ELEKYEQACNEFTTHVMNLLREQSRTRP
Sbjct: 133 AAASGGAGS-DNSVEHSDYRAKLSQIRQIYHTELEKYEQACNEFTTHVMNLLREQSRTRP 191

Query: 203 VAPKEMERMVSIIHRKFSAIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEVLNEY 262
           ++PKE+ERMVSIIHRKFS+IQMQLKQSTCEAVMILRSRFLDARRKRRNF+KQATE+LNEY
Sbjct: 192 ISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFNKQATEILNEY 251

Query: 263 FYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQEEANIYAVKTAV 322
           FYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQEEANIYA KTAV
Sbjct: 252 FYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQEEANIYAAKTAV 311

Query: 323 SVTQ-GGH-SRTSSPTPPSSAGSGGSFNLSGSGDMFLGMPGLNGDSYSA--------SQV 372
           + T    H S+ +SP+ P+SAGS  SFN+S SGD+F+ +  LNGDSY          SQV
Sbjct: 312 TATNVSAHGSQANSPSTPNSAGSSSSFNMSNSGDLFMSVQSLNGDSYQGAQVGANVQSQV 371

Query: 373 ESLRHSMG-PGGYGDNLGGGQMYSPREMRANGSWQEAVTPSSVTSPTEGPGSVHSDTSN 430
           ++LRH +   GGY D L   QMYSP+ + ANG WQ+A TPSSVTSPTEGPGSVHSDTSN
Sbjct: 372 DTLRHVISQTGGYSDGLAASQMYSPQGISANGGWQDATTPSSVTSPTEGPGSVHSDTSN 430


>gi|5453852 pre-B-cell leukemia homeobox 3 isoform 1 [Homo sapiens]
          Length = 434

 Score =  631 bits (1627), Expect = 0.0
 Identities = 327/419 (78%), Positives = 351/419 (83%), Gaps = 21/419 (5%)

Query: 26  GGPGEPPGGGDPGGGSGGVPGGRGKQDIGDILQQIMTITDQSLDEAQAKKHALNCHRMKP 85
           GG   PP    P  G  G  G   KQDIGDIL QIMTITDQSLDEAQAKKHALNCHRMKP
Sbjct: 23  GGMALPP----PPHGHEGADGDGRKQDIGDILHQIMTITDQSLDEAQAKKHALNCHRMKP 78

Query: 86  ALFSVLCEIKEKTGLSIRSSQEEEPVDPQLMRLDNMLLAEGVAGPEKGGGSAAAAAAAAA 145
           ALFSVLCEIKEKTGLSIR +QEE+P DPQLMRLDNMLLAEGV+GPEKGGGSAAAAAAAAA
Sbjct: 79  ALFSVLCEIKEKTGLSIRGAQEEDPPDPQLMRLDNMLLAEGVSGPEKGGGSAAAAAAAAA 138

Query: 146 SGGGVSPDNSIEHSDYRSKLAQIRHIYHSELEKYEQACNEFTTHVMNLLREQSRTRPVAP 205
           SGG  S DNSIEHSDYR+KL QIR IYH+ELEKYEQACNEFTTHVMNLLREQSRTRP++P
Sbjct: 139 SGG--SSDNSIEHSDYRAKLTQIRQIYHTELEKYEQACNEFTTHVMNLLREQSRTRPISP 196

Query: 206 KEMERMVSIIHRKFSAIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEVLNEYFYS 265
           KE+ERMV IIHRKFS+IQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATE+LNEYFYS
Sbjct: 197 KEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEILNEYFYS 256

Query: 266 HLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQEEANIYAVKTAVSVT 325
           HLSNPYPSEEAKEELAKKC ITVSQVSNWFGNKRIRYKKNIGKFQEEAN+YA KTAV+  
Sbjct: 257 HLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRYKKNIGKFQEEANLYAAKTAVTAA 316

Query: 326 QG-----GHSRTSSPTPPSSAGSGGSFNLSGSGDMFLGMPGLNGDSYSA--------SQV 372
                   +++T+SPT P+S GS GSFNL  SGDMF+ M  LNGDSY          SQV
Sbjct: 317 HAVAAAVQNNQTNSPTTPNS-GSSGSFNLPNSGDMFMNMQSLNGDSYQGSQVGANVQSQV 375

Query: 373 ESLRHSMG-PGGYGDNLGGGQMYSPREMRANGSWQEAVTPSSVTSPTEGPGSVHSDTSN 430
           ++LRH +   GGY D LGG  +YSP  + ANG WQ+A TPSSVTSPTEGPGSVHSDTSN
Sbjct: 376 DTLRHVINQTGGYSDGLGGNSLYSPHNLNANGGWQDATTPSSVTSPTEGPGSVHSDTSN 434


>gi|198041755 pre-B-cell leukemia homeobox 3 isoform 2 [Homo
           sapiens]
          Length = 359

 Score =  560 bits (1444), Expect = e-160
 Identities = 287/362 (79%), Positives = 311/362 (85%), Gaps = 17/362 (4%)

Query: 83  MKPALFSVLCEIKEKTGLSIRSSQEEEPVDPQLMRLDNMLLAEGVAGPEKGGGSAAAAAA 142
           MKPALFSVLCEIKEKTGLSIR +QEE+P DPQLMRLDNMLLAEGV+GPEKGGGSAAAAAA
Sbjct: 1   MKPALFSVLCEIKEKTGLSIRGAQEEDPPDPQLMRLDNMLLAEGVSGPEKGGGSAAAAAA 60

Query: 143 AAASGGGVSPDNSIEHSDYRSKLAQIRHIYHSELEKYEQACNEFTTHVMNLLREQSRTRP 202
           AAASGG  S DNSIEHSDYR+KL QIR IYH+ELEKYEQACNEFTTHVMNLLREQSRTRP
Sbjct: 61  AAASGG--SSDNSIEHSDYRAKLTQIRQIYHTELEKYEQACNEFTTHVMNLLREQSRTRP 118

Query: 203 VAPKEMERMVSIIHRKFSAIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEVLNEY 262
           ++PKE+ERMV IIHRKFS+IQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATE+LNEY
Sbjct: 119 ISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEILNEY 178

Query: 263 FYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQEEANIYAVKTAV 322
           FYSHLSNPYPSEEAKEELAKKC ITVSQVSNWFGNKRIRYKKNIGKFQEEAN+YA KTAV
Sbjct: 179 FYSHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRYKKNIGKFQEEANLYAAKTAV 238

Query: 323 SVTQG-----GHSRTSSPTPPSSAGSGGSFNLSGSGDMFLGMPGLNGDSYSA-------- 369
           +          +++T+SPT P+S GS GSFNL  SGDMF+ M  LNGDSY          
Sbjct: 239 TAAHAVAAAVQNNQTNSPTTPNS-GSSGSFNLPNSGDMFMNMQSLNGDSYQGSQVGANVQ 297

Query: 370 SQVESLRHSMG-PGGYGDNLGGGQMYSPREMRANGSWQEAVTPSSVTSPTEGPGSVHSDT 428
           SQV++LRH +   GGY D LGG  +YSP  + ANG WQ+A TPSSVTSPTEGPGSVHSDT
Sbjct: 298 SQVDTLRHVINQTGGYSDGLGGNSLYSPHNLNANGGWQDATTPSSVTSPTEGPGSVHSDT 357

Query: 429 SN 430
           SN
Sbjct: 358 SN 359


>gi|15149472 pre-B-cell leukemia homeobox 4 [Homo sapiens]
          Length = 374

 Score =  472 bits (1214), Expect = e-133
 Identities = 258/390 (66%), Positives = 287/390 (73%), Gaps = 30/390 (7%)

Query: 45  PGGRGKQDIGDILQQIMTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRS 104
           P    + D  D+LQQIM ITDQSLDEAQA+KHALNCHRMKPALFSVLCEIKEKT +SIR 
Sbjct: 11  PPAPRRLDTSDVLQQIMAITDQSLDEAQARKHALNCHRMKPALFSVLCEIKEKTVVSIRG 70

Query: 105 SQEEEPVDPQLMRLDNMLLAEGVAGPEKGGGSAAAAAAAAASGGGVSPDNSIEHSDYRSK 164
            Q+E+P D QL+RLDNMLLAEGV  PEK G   A A A  A+ GG   DNSIEHSDYR+K
Sbjct: 71  IQDEDPPDAQLLRLDNMLLAEGVCRPEKRGRGGAVARAGTATPGGCPNDNSIEHSDYRAK 130

Query: 165 LAQIRHIYHSELEKYEQACNEFTTHVMNLLREQSRTRPVAPKEMERMVSIIHRKFSAIQM 224
           L+QIR IYHSELEKYEQAC EFTTHV NLL+EQSR RPV+PKE+ERMV  IH KFSAIQM
Sbjct: 131 LSQIRQIYHSELEKYEQACREFTTHVTNLLQEQSRMRPVSPKEIERMVGAIHGKFSAIQM 190

Query: 225 QLKQSTCEAVMILRSRFLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKC 284
           QLKQSTCEAVM LRSR LDARRKRRNFSKQATEVLNEYFYSHL+NPYPSEEAKEELA+K 
Sbjct: 191 QLKQSTCEAVMTLRSRLLDARRKRRNFSKQATEVLNEYFYSHLNNPYPSEEAKEELARKG 250

Query: 285 GITVSQVSNWFGNKRIRYKKNIGKFQEEANIYAVKTAVSVTQ----GGHSRTSSPTPPSS 340
           G+T+SQVSNWFGNKRIRYKKN+GKFQEEA IY  KTAV  T+    G H+   S TP  S
Sbjct: 251 GLTISQVSNWFGNKRIRYKKNMGKFQEEATIYTGKTAVDTTEVGVPGNHASCLS-TP--S 307

Query: 341 AGSGGSFNLSGSGDMFLGMPGLNGDSYSASQVESLRHSMGPGGYGDNLGGGQMYSPREMR 400
           +GS G F L  +GD FL +  L               S+ P       GGG + S    +
Sbjct: 308 SGSSGPFPLPSAGDAFLTLRTL--------------ASLQPPP-----GGGCLQS----Q 344

Query: 401 ANGSWQEAVTPSSVTSPTEGPGSVHSDTSN 430
           A GSWQ A    +  SP   PGS++S TSN
Sbjct: 345 AQGSWQGATPQPATASPAGDPGSINSSTSN 374


>gi|57863279 Meis1, myeloid ecotropic viral integration site 1
           homolog 3 isoform 2 [Homo sapiens]
          Length = 358

 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 40/109 (36%), Positives = 58/109 (53%), Gaps = 5/109 (4%)

Query: 246 RKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKN 305
           +KR  F K AT ++  + + HLS+PYPSEE K++LA+  G+T+ QV+NWF N R R  + 
Sbjct: 247 KKRGIFPKVATNIMRAWLFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQP 306

Query: 306 IGKFQEEANIYAVKTAVSVTQGGHSRTS---SPTPPSSAGSGGSFNLSG 351
           +          A  +      GG++ T    +  PP S G   S NL G
Sbjct: 307 MIDQSNRTGQGAAFSPEGQPIGGYTETQPHVAVRPPGSVGM--SLNLEG 353


>gi|24762241 Meis homeobox 2 isoform c [Homo sapiens]
          Length = 477

 Score = 66.2 bits (160), Expect = 5e-11
 Identities = 43/128 (33%), Positives = 68/128 (53%), Gaps = 15/128 (11%)

Query: 245 RRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKK 304
           ++KR  F K AT ++  + + HL++PYPSEE K++LA+  G+T+ QV+NWF N R   ++
Sbjct: 277 QKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINAR---RR 333

Query: 305 NIGKFQEEANIYAVKTAVSVTQG-GHSRTSSPTPPSSAGSGGSFNLSGSGDMFL---GMP 360
            +    +++N        SV+QG  +S    P         GSF L G   M +   G+ 
Sbjct: 334 IVQPMIDQSNRAGFLLDPSVSQGAAYSPEGQPM--------GSFVLDGQQHMGIRPAGLQ 385

Query: 361 GLNGDSYS 368
            + GD  S
Sbjct: 386 SMPGDYVS 393


>gi|27502381 Meis homeobox 2 isoform g [Homo sapiens]
          Length = 388

 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 39/112 (34%), Positives = 61/112 (54%), Gaps = 12/112 (10%)

Query: 245 RRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKK 304
           ++KR  F K AT ++  + + HL++PYPSEE K++LA+  G+T+ QV+NWF N R   ++
Sbjct: 264 QKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINAR---RR 320

Query: 305 NIGKFQEEANIYAVKTAVSVTQG-GHSRTSSPTPPSSAGSGGSFNLSGSGDM 355
            +    +++N        SV+QG  +S    P         GSF L G   M
Sbjct: 321 IVQPMIDQSNRAGFLLDPSVSQGAAYSPEGQPM--------GSFVLDGQQHM 364


>gi|24762244 Meis homeobox 2 isoform a [Homo sapiens]
          Length = 401

 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 39/112 (34%), Positives = 61/112 (54%), Gaps = 12/112 (10%)

Query: 245 RRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKK 304
           ++KR  F K AT ++  + + HL++PYPSEE K++LA+  G+T+ QV+NWF N R   ++
Sbjct: 277 QKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINAR---RR 333

Query: 305 NIGKFQEEANIYAVKTAVSVTQG-GHSRTSSPTPPSSAGSGGSFNLSGSGDM 355
            +    +++N        SV+QG  +S    P         GSF L G   M
Sbjct: 334 IVQPMIDQSNRAGFLLDPSVSQGAAYSPEGQPM--------GSFVLDGQQHM 377


>gi|4505151 Meis homeobox 1 [Homo sapiens]
          Length = 390

 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 39/116 (33%), Positives = 63/116 (54%), Gaps = 17/116 (14%)

Query: 246 RKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKN 305
           +KR  F K AT ++  + + HL++PYPSEE K++LA+  G+T+ QV+NWF N R   ++ 
Sbjct: 274 KKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINAR---RRI 330

Query: 306 IGKFQEEANIYAVKTAVSVTQGGHSRTSSPTPPSSAGSGGSFNLSGSGDMFLGMPG 361
           +    +++N        +V+QG      +P  P     GG F + G   M +  PG
Sbjct: 331 VQPMIDQSN-------RAVSQG------TPYNPDGQPMGG-FVMDGQQHMGIRAPG 372


>gi|27502383 Meis homeobox 2 isoform h [Homo sapiens]
          Length = 306

 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 27/57 (47%), Positives = 41/57 (71%)

Query: 245 RRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIR 301
           ++KR  F K AT ++  + + HL++PYPSEE K++LA+  G+T+ QV+NWF N R R
Sbjct: 189 QKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRR 245


>gi|24762250 Meis homeobox 2 isoform d [Homo sapiens]
          Length = 470

 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 27/57 (47%), Positives = 41/57 (71%)

Query: 245 RRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIR 301
           ++KR  F K AT ++  + + HL++PYPSEE K++LA+  G+T+ QV+NWF N R R
Sbjct: 277 QKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRR 333


>gi|24762246 Meis homeobox 2 isoform b [Homo sapiens]
          Length = 394

 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 27/57 (47%), Positives = 41/57 (71%)

Query: 245 RRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIR 301
           ++KR  F K AT ++  + + HL++PYPSEE K++LA+  G+T+ QV+NWF N R R
Sbjct: 277 QKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRR 333


>gi|24762225 Meis homeobox 2 isoform f [Homo sapiens]
          Length = 381

 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 27/57 (47%), Positives = 41/57 (71%)

Query: 245 RRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIR 301
           ++KR  F K AT ++  + + HL++PYPSEE K++LA+  G+T+ QV+NWF N R R
Sbjct: 264 QKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRR 320


>gi|4885597 sine oculis homeobox homolog 3 [Homo sapiens]
          Length = 332

 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 84/345 (24%), Positives = 118/345 (34%), Gaps = 76/345 (22%)

Query: 5   LLGPPPPGGGRGGLGLVSGEPGGPGEPPGGGDPGGGSGGVPGGRGKQDIGDILQQIMTIT 64
           LL     G G GG G   G  GG     GGG  G G GG  G R   +   + Q      
Sbjct: 28  LLASSGGGNGAGGGGGAGGGSGGGNGAGGGGAGGAGGGGGGGSRAPPEELSMFQ------ 81

Query: 65  DQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRSSQEEEPVDPQLMRLDNML-- 122
                        L      P   + +CE  E+TG               + RL   L  
Sbjct: 82  -------------LPTLNFSPEQVASVCETLEETG--------------DIERLGRFLWS 114

Query: 123 --LAEGVAGPEKGGGSAAAAAAAAASGGGVSPDNSIEHSDYRSKLAQIRH--IYHSELEK 178
             +A G         S   A A  A   G   D  + H     K  +  H  +    LE 
Sbjct: 115 LPVAPGACEAINKHESILRARAVVAFHTGNFRD--LYHILENHKFTKESHGKLQAMWLEA 172

Query: 179 YEQACNEFTTHVMNLLREQSRTRPVAPKEMERMVSIIHRKFSAIQMQLKQSTCEAVMILR 238
           + Q              E+ R RP+ P +  R    + +KF                 L 
Sbjct: 173 HYQEA------------EKLRGRPLGPVDKYR----VRKKFP----------------LP 200

Query: 239 SRFLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNK 298
               D  +K   F ++   +L E++   L +PYP+   K ELA+  G+T +QV NWF N+
Sbjct: 201 RTIWDGEQKTHCFKERTRSLLREWY---LQDPYPNPSKKRELAQATGLTPTQVGNWFKNR 257

Query: 299 RIRYKKNIGKFQEEANIYAVKTAVSVTQGGHSRTSSPTPPSSAGS 343
           R R +    K + +          S+ + G     S   PS+A S
Sbjct: 258 RQRDRAAAAKNRLQHQAIGPSGMRSLAEPGCPTHGSAESPSTAAS 302


>gi|116812644 PBX/knotted 1 homeobox 2 [Homo sapiens]
          Length = 472

 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 28/81 (34%), Positives = 47/81 (58%)

Query: 221 AIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEEL 280
           AIQ+Q  Q   +   +L +    ++ KR    K AT ++  + + HL +PYP+E+ K ++
Sbjct: 265 AIQIQNTQVNLDLTSLLDNEDKKSKNKRGVLPKHATNIMRSWLFQHLMHPYPTEDEKRQI 324

Query: 281 AKKCGITVSQVSNWFGNKRIR 301
           A +  +T+ QV+NWF N R R
Sbjct: 325 AAQTNLTLLQVNNWFINARRR 345


>gi|28866955 PBX/knotted 1 homeobox 1 [Homo sapiens]
          Length = 436

 Score = 58.9 bits (141), Expect = 8e-09
 Identities = 29/82 (35%), Positives = 48/82 (58%), Gaps = 4/82 (4%)

Query: 220 SAIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEE 279
           S +Q+QL Q     + IL      ++ KR    K AT V+  + + H+ +PYP+E+ K++
Sbjct: 239 SQLQLQLNQD----LSILHQDDGSSKNKRGVLPKHATNVMRSWLFQHIGHPYPTEDEKKQ 294

Query: 280 LAKKCGITVSQVSNWFGNKRIR 301
           +A +  +T+ QV+NWF N R R
Sbjct: 295 IAAQTNLTLLQVNNWFINARRR 316


>gi|34328941 TGFB-induced factor homeobox 2-like, X-linked [Homo
           sapiens]
          Length = 241

 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 28/105 (26%), Positives = 56/105 (53%), Gaps = 1/105 (0%)

Query: 245 RRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKK 304
           ++++ N   ++ ++L ++ Y H    YPSEE K+ L++K  +++ Q+SNWF N R R   
Sbjct: 51  KKRKGNLPAESVKILRDWMYKHRFKAYPSEEEKQMLSEKTNLSLLQISNWFINARRRILP 110

Query: 305 NIGKFQEEANIYAVKTAVSVTQGGHSRTSSPTPPSSAGSGGSFNL 349
           ++ + +    I   KT        H +++  + P+ +G  G  N+
Sbjct: 111 DMLQQRRNDPIIGHKTGKD-AHATHLQSTEASVPAKSGPSGPDNV 154


>gi|219275578 SIX homeobox 2 [Homo sapiens]
          Length = 291

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 43/141 (30%), Positives = 62/141 (43%), Gaps = 9/141 (6%)

Query: 251 FSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQ 310
           F +++  VL E+ Y+H  NPYPS   K ELA+  G+T +QVSNWF N+R R +    K +
Sbjct: 131 FKEKSRSVLREW-YAH--NPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAK-E 186

Query: 311 EEANIYAVKTAVSVTQGGHSRTSSPTPPSSAGSGGSFNLSGSGDMFLGMPGLNGDSYSAS 370
            E N  +   + +   G        +      SG   + S S  + L  P          
Sbjct: 187 RENNENSNSNSHNPLNGSGKSVLGSSEDEKTPSGTPDHSSSSPALLLSPP-----PPGLP 241

Query: 371 QVESLRHSMGPGGYGDNLGGG 391
            + SL H  GP      + GG
Sbjct: 242 SLHSLGHPPGPSAVPVPVPGG 262


>gi|5174681 SIX homeobox 1 [Homo sapiens]
          Length = 284

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 38/110 (34%), Positives = 55/110 (50%), Gaps = 11/110 (10%)

Query: 251 FSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQ 310
           F +++  VL E+ Y+H  NPYPS   K ELA+  G+T +QVSNWF N+R R +    K +
Sbjct: 131 FKEKSRGVLREW-YAH--NPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKER 187

Query: 311 EEA----NIYAVKTAVSVTQGGHSRTSSP----TPPSSAGSGGSFNLSGS 352
           E      +    +  +S  +GG    SS     +PP S        L G+
Sbjct: 188 ENTENNNSSSNKQNQLSPLEGGKPLMSSSEEEFSPPQSPDQNSVLLLQGN 237


>gi|28178843 TG-interacting factor isoform a [Homo sapiens]
          Length = 401

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 23/57 (40%), Positives = 36/57 (63%)

Query: 245 RRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIR 301
           RR+R N  K++ ++L ++ Y H  N YPSE+ K  L+++  ++  QV NWF N R R
Sbjct: 165 RRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRR 221


>gi|4507473 TG-interacting factor isoform c [Homo sapiens]
          Length = 272

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 23/57 (40%), Positives = 36/57 (63%)

Query: 245 RRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIR 301
           RR+R N  K++ ++L ++ Y H  N YPSE+ K  L+++  ++  QV NWF N R R
Sbjct: 36  RRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRR 92


>gi|28178855 TG-interacting factor isoform d [Homo sapiens]
          Length = 252

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 23/57 (40%), Positives = 36/57 (63%)

Query: 245 RRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIR 301
           RR+R N  K++ ++L ++ Y H  N YPSE+ K  L+++  ++  QV NWF N R R
Sbjct: 16  RRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRR 72


>gi|28178853 TG-interacting factor isoform d [Homo sapiens]
          Length = 252

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 23/57 (40%), Positives = 36/57 (63%)

Query: 245 RRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIR 301
           RR+R N  K++ ++L ++ Y H  N YPSE+ K  L+++  ++  QV NWF N R R
Sbjct: 16  RRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRR 72


>gi|28178851 TG-interacting factor isoform d [Homo sapiens]
          Length = 252

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 23/57 (40%), Positives = 36/57 (63%)

Query: 245 RRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIR 301
           RR+R N  K++ ++L ++ Y H  N YPSE+ K  L+++  ++  QV NWF N R R
Sbjct: 16  RRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRR 72


>gi|28178857 TG-interacting factor isoform d [Homo sapiens]
          Length = 252

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 23/57 (40%), Positives = 36/57 (63%)

Query: 245 RRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIR 301
           RR+R N  K++ ++L ++ Y H  N YPSE+ K  L+++  ++  QV NWF N R R
Sbjct: 16  RRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRR 72


>gi|28178849 TG-interacting factor isoform c [Homo sapiens]
          Length = 272

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 23/57 (40%), Positives = 36/57 (63%)

Query: 245 RRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIR 301
           RR+R N  K++ ++L ++ Y H  N YPSE+ K  L+++  ++  QV NWF N R R
Sbjct: 36  RRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRR 92


>gi|28178845 TG-interacting factor isoform b [Homo sapiens]
          Length = 286

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 23/57 (40%), Positives = 36/57 (63%)

Query: 245 RRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIR 301
           RR+R N  K++ ++L ++ Y H  N YPSE+ K  L+++  ++  QV NWF N R R
Sbjct: 50  RRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRR 106


>gi|21245108 TGFB-induced factor homeobox 2-like, Y-linked [Homo
           sapiens]
          Length = 185

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 25/98 (25%), Positives = 53/98 (54%), Gaps = 1/98 (1%)

Query: 245 RRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKK 304
           ++++ N   ++ ++L ++ Y H    YPSEE K+ L++K  +++ ++SNWF N R R   
Sbjct: 51  KKRKGNLPAESVKILRDWMYKHRFKAYPSEEEKQMLSEKTNLSLLRISNWFINARRRILP 110

Query: 305 NIGKFQEEANIYAVKTAVSVTQGGHSRTSSPTPPSSAG 342
           ++ + +    I   KT        H +++  + P+ +G
Sbjct: 111 DMLQQRRNDPIIGHKTGKD-AHATHLQSTEASVPAKSG 147


>gi|7705555 iroquois homeobox 4 [Homo sapiens]
          Length = 519

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 24/63 (38%), Positives = 37/63 (58%)

Query: 242 LDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIR 301
           +D+  +R+N +++ T  L  +   H  NPYP++  K  LA    +T++QVS WF N R R
Sbjct: 140 MDSGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRR 199

Query: 302 YKK 304
            KK
Sbjct: 200 LKK 202


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.130    0.378 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,594,254
Number of Sequences: 37866
Number of extensions: 1225046
Number of successful extensions: 17904
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 475
Number of HSP's successfully gapped in prelim test: 383
Number of HSP's that attempted gapping in prelim test: 8207
Number of HSP's gapped (non-prelim): 6847
length of query: 430
length of database: 18,247,518
effective HSP length: 105
effective length of query: 325
effective length of database: 14,271,588
effective search space: 4638266100
effective search space used: 4638266100
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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